somatic-hypermutations

Here are 4 public repositories matching this topic...

Rashedul / CRIS

Construction of IHGV sequences from RNA-seq

bioinformatics gene rna-seq genomics sequencing immunoglobulin vdj-recombination cll vdj ihgv-transcripts ighv somatic-hypermutations ighv-status ighv3

Updated Oct 22, 2025
Shell

platforma-open / mixcr-shm-trees

Star

Build somatic hypermutation (SHM) lineage trees from antibody repertoire sequencing data. Reconstruct clonal relationships between antibody sequences and visualize how B-cell receptor (BCR) clones diversify during somatic hypermutation and affinity maturation.

bcr-seq somatic-hypermutations antibody-discovery

Updated Aug 14, 2026
Vue

enricvercher / Analisis_single_cell_BCR

Star

Single-cell transcriptomic and B-lymphocyte repertoire analysis with R (Seurat)

annotations clonality bcr somatic-hypermutations

Updated Mar 21, 2025
Shell

platforma-open / repertoire-score

Star

Rank clonotypes as antibody leads on all the evidence at once - maturation, abundance, convergence, and generation-probability signals into a single tunable score between 0 and 1

bcr immune-repertoire somatic-hypermutations antibody-discovery

Updated Sep 3, 2026
TypeScript

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