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The Primate Genome-phenome Archive (PGA)

This repository contains core data files for the Primate Genome-phenome Archive (PGA), a curated resource integrating genetic and phenotypic information from non-human primates.

The PGA dataset is part of the project Valenzuela et al., 2025, and provides a foundation for evolutionary, biomedical, and comparative analyses linking genotype to phenotype across primates.

Repository Structure

├── genetic.information
│   ├── ALL_RER_CONVERGE_UNIQUE_MAR23.txt
│   └── CAAS_FINAL_MAR23.tab
├── LICENSE
├── phenotype.tables
│   ├── caas.discovery.groups.csv
│   ├── caas.results.csv
│   ├── human.equivalent.measurements.csv
│   ├── metadata.qualitative.traits.csv
│   ├── metadata.quantitative.traits.csv
│   ├── nhp.phenomic.dataset.csv
│   ├── trait.data.sources.csv
│   └── traits.redundancy.csv
└── README.md

genetic.information/

This folder contains gene-level evolutionary signals, including:

  • CAAS_FINAL_MAR23.tab: Final list of convergent amino acid substitutions (CAAS) detected across primates.
  • ALL_RER_CONVERGE_UNIQUE_MAR23.txt: Genes showing significant rate shifts (RERconverge) associated with phenotype convergence.

phenotype.tables/

This folder includes phenotype tables describing ~230 traits measured across ~220 primate species. The data include:

  • Trait metadata (quantitative and qualitative)
  • Cross-species harmonization (e.g., human equivalent units)
  • Trait grouping and redundancy curation
  • Results of gene-trait association analyses

For a detailed explanation of each file, please refer to the official PGA documentation:

📄 Download the PDF documentation

License

This repository is distributed under the GNU General Public License v3.0.
See the LICENSE file for details.


Part of the project "Valenzuela et al., 2025".

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The Primate Genome-phenome Archive (PGA). Complete dataset.

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