PopPK FitCheckR

PopPK FitCheckR is an R package containing a Shiny application for interactive goodness-of-fit diagnostics and correlation plots from NONMEM output table files.

Install

Install the runtime dependencies, then install the package from GitHub:

install.packages(c(
  "bslib", "dplyr", "ggplot2", "ggpmisc", "gridExtra",
  "plotly", "rlang", "scales", "shiny", "stringdist"
))
install.packages("remotes")
remotes::install_github("MSDLLCpapers/PopPK_FitCheckR")

Run

PopPKFitCheckR::run_app()

Input files

The GOF tab accepts a NONMEM output table containing DV, PRED, IPRED, CWRES, TIME, and ID (e.g. an sdtab). The correlation tab accepts a parameter or covariate table (e.g. a patab or cotab). Both tabs read whitespace-delimited NONMEM tables, with or without the TABLE NO. banner, as well as .csv files.