Issues

• Research hold: resolve native nataxazole regulation and transport mechanisms

  CultureBotAI/NaturalProductMech#810 · Filter by author realmarcin opened on Oct 11, 2026

• Research hold: resolve nataxazole core reactions, constructs and final-product completion

  CultureBotAI/NaturalProductMech#808 · Filter by author realmarcin opened on Oct 11, 2026

• Research hold: resolve m9-20 product stereochemistry and MxcF/PPTase assignments

  CultureBotAI/NaturalProductMech#805 · Filter by author realmarcin opened on Oct 11, 2026

• Audit rabelomycin S/R identity before expanding protein graphs

  CultureBotAI/NaturalProductMech#803 · Filter by author realmarcin opened on Oct 11, 2026
  1

• Reconcile four unparsable cyclopiazonic-acid ChEBI source SMILES without changing valid owners

  CultureBotAI/NaturalProductMech#777 · Filter by author realmarcin opened on Oct 10, 2026

• Reconcile unparsable CHEBI:64534 source SMILES without changing the valid terrequinone owner

  CultureBotAI/NaturalProductMech#773 · Filter by author realmarcin opened on Oct 10, 2026

• Resolve hopene BGC0000663 exact-identity mismatch with PubChem CID 92155

  CultureBotAI/NaturalProductMech#770 · Filter by author realmarcin opened on Oct 10, 2026

• Reconcile petrobactin structure identities before protein graph curation

  CultureBotAI/NaturalProductMech#754 · Filter by author realmarcin opened on Oct 9, 2026

• Audit conflicting gene assignments in MIBiG BGC0000944 v5

  CultureBotAI/NaturalProductMech#752 · Filter by author realmarcin opened on Oct 9, 2026

• Curation hold: reconcile KIOM G15050 PUL protein genetic-code mismatch

  CultureBotAI/NaturalProductMech#750 · Filter by author realmarcin opened on Oct 9, 2026

• Review BGC0000673 product stereochemistry before PbcR/PbcA graph curation

  CultureBotAI/NaturalProductMech#735 · Filter by author realmarcin opened on Oct 9, 2026

• Resolve BGC0000657 2-methylisoborneol label versus brominated C15 structure

  CultureBotAI/NaturalProductMech#724 · Filter by author realmarcin opened on Oct 9, 2026
  1

• Resolve alnumycin A stereochemical identity before enzyme-product grounding

  CultureBotAI/NaturalProductMech#723 · Filter by author realmarcin opened on Oct 8, 2026

• Resolve conflicting curacin A stereochemistry and shared structure xrefs before protein curation

  CultureBotAI/NaturalProductMech#720 · Filter by author realmarcin opened on Oct 8, 2026
  2

• Clarify curator-authored versus source-backed biosynthesis page wording

  CultureBotAI/NaturalProductMech#716 · Filter by author realmarcin opened on Oct 8, 2026

• Hold BtcB grounding: betaestacin I literal model has different formula/connectivity

  CultureBotAI/NaturalProductMech#715 · Filter by author realmarcin opened on Oct 8, 2026

• Hold TiaM exact-product grounding: three alkene configurations conflict with tiacumicin B

  CultureBotAI/NaturalProductMech#713 · Filter by author realmarcin opened on Oct 8, 2026

• Reconcile FD-891 owner structure and GfsF taxon before protein/reaction adoption

  CultureBotAI/NaturalProductMech#705 · Filter by author realmarcin opened on Oct 8, 2026
  1

• Curation hold: StrB reaction SMARTS disagrees with listed product stereochemistry

  CultureBotAI/NaturalProductMech#702 · Filter by author realmarcin opened on Oct 8, 2026
  1

• Curation hold: resolve KtzA/KtzD model chemistry before Kutzneride 1 reactions

  CultureBotAI/NaturalProductMech#700 · Filter by author realmarcin opened on Oct 8, 2026
  1

• Intake hold: reconcile SorR/MITE0000468 reaction label and modeled chemistry

  CultureBotAI/NaturalProductMech#697 · Filter by author realmarcin opened on Oct 8, 2026
  1

• Intake hold: reconcile SCO6281/MITE0000339 reaction label and modeled chemistry

  CultureBotAI/NaturalProductMech#695 · Filter by author realmarcin opened on Oct 8, 2026

• Hold NotB ingestion: pinned C/D structure-label conflict and sequence-model mismatch

  CultureBotAI/NaturalProductMech#691 · Filter by author realmarcin opened on Oct 8, 2026

• Resolve JuiI source-product connectivity mismatch before Julichrome graph adoption

  CultureBotAI/NaturalProductMech#675 · Filter by author realmarcin opened on Oct 7, 2026

• Resolve tirandamycin chemical-form and stereochemistry conflict before Tam protein graphs

  CultureBotAI/NaturalProductMech#674 · Filter by author realmarcin opened on Oct 7, 2026