diff --git a/.gitignore b/.gitignore index b3901eb..7536acb 100644 --- a/.gitignore +++ b/.gitignore @@ -59,3 +59,18 @@ dist/ # Solver gurobi.env gurobi.log + +# Built ecModels of the literature datasets +literature/**/models/ + +# Regenerated by literature/xia2022/scripts and comparison +literature/xia2022/comparison/respiratory_limit/ +# Outputs of the Xia run that the comparison does not read +literature/xia2022/results/modelSimulation/ +literature/xia2022/results/enzymeUsage/*.pdf +literature/xia2022/results/enzymeUsage/systemMedians.tsv +literature/xia2022/results/modelGeneration/average* +literature/xia2022/results/modelGeneration/modifiedRibosomeSubunits_* +literature/xia2022/results/modelGeneration/ribosomeSummary.tsv +literature/xia2022/results/randomSampling/altExchangeFlux.tsv +literature/xia2022/derived_kcats/respiratory_limit/ diff --git a/README.md b/README.md index 8ddf2ca..80041c2 100644 --- a/README.md +++ b/README.md @@ -33,6 +33,7 @@ unavailable solver is an error, not a silent switch. | `tests/` | Test suite | | `results/` | Output tables and figures | | `legacy_matlab/` | The GECKO 2 MATLAB implementation and its results | +| `literature/` | The analysis run on published datasets, and their comparison with `results/` | ## Experimental data @@ -71,6 +72,33 @@ Each condition gets `models/ecModel_P_.yml` and, in `results/`, the enzymes whose measured abundance the model could not run on, the enzymes whose caps had to be released, and the full flux distribution. +### From proteomics to enzyme caps + +Each measured abundance (the filtered mean + 1.96 SD of the replicates) caps its +enzyme's usage. Enzyme complexes are handled as one unit throughout +(`overflow.complexes`): + +1. **Complex levelling.** Absolute proteomics recovers the subunits of one complex + unevenly: subunits present 1:1 can come out tenfold apart while their replicates + agree within a few percent. Each complex therefore gets one abundance, the median + per copy over its measured subunits, written back to every subunit by its copies in + the model; unmeasured subunits of a complex are filled. Enzyme sets that share at + least two subunits and half the larger set (isozyme variants) are one complex. + Proteins in several complexes, or that also work alone, keep their own measurement: + cytochrome c, thioredoxin and LPD1, the E3 subunit of pyruvate dehydrogenase, + 2-oxoglutarate dehydrogenase and the glycine cleavage system. `--no-complex-fix` + turns levelling off. +2. **Minimum usage.** On a model limited only by the protein pool, a complex the model + cannot run at the dilution rate for less than its measured abundance is raised to + what it needs. +3. **Reaching the dilution rate.** One LP finds the least relaxation that lets the + model grow at the dilution rate (`relax_to_growth`): it minimises the summed fold + increases of the measured caps, one fold per complex, with the protein pool allowed + to grow at 1000 times the price of a cap. The result does not depend on the order in + which limiting enzymes are found. +4. **Measured rates.** With `--fit-rates`, the same LP under the measured exchange + rates raises the caps further by the least that reproduces them. + Options change what the models are asked to account for: - `--fit-rates` holds CO2, oxygen and the byproducts within a tolerance of their @@ -159,6 +187,26 @@ Writes `results/COMPARISON.md`: predicted exchange rates, median capacity usage per system and the sampled ATP and redox budget, this pipeline beside the MATLAB one, read from `legacy_matlab/results/`. +## Respiratory-chain kcats + +With the ecModel's kcats (complex III 290/s and complex IV 1376/s, from BRENDA; ATP +synthase 85/s), the measured respiratory chain cannot carry the measured respiration +in several conditions, so the build raises its abundances to what the fluxes need and +its capacity usage reads 100% by construction. `overflow.respiratory_kcats` derives +these three kcats from the data instead. In every condition the apparent turnover of a +complex is its sampled flux over the complex abundance the build uses (the filtered +mean + 1.96 SD of its measured subunits, levelled to the median per copy). The +highest apparent turnover across the conditions becomes the complex's kcat, which +`overflow.build --respiratory-kcats` applies to every isozyme variant before building. +No other kcat changes. + +Two assumptions follow: the condition that sets a kcat runs that complex at full +capacity, so its saturation is built in and the derived kcat is a lower bound; and a +dataset's kcats come from its own abundances, so a difference in absolute protein +quantification between datasets cancels for the respiratory chain. The turnovers and +kcats are in `results/modelGeneration/respiratoryTurnover.tsv` and +`respiratoryKcats.tsv`. + ## Running the whole analysis The analysis is run with `--fit-rates`, implemented in `overflow.build` @@ -171,13 +219,18 @@ measured physiology. `--uptake-flex 1.08` gives CN4 the glucose it needs, and `- proton leak (see the build options). ```bash -python -m overflow.build --fit-rates --rate-tolerance 0.08 --uptake-flex 1.08 --block r_2129 +python -m overflow.run_sampling --procs 12 +python -m overflow.respiratory_kcats +python -m overflow.build --fit-rates --rate-tolerance 0.08 --uptake-flex 1.08 --block r_2129 \ + --respiratory-kcats results/modelGeneration/respiratoryKcats.tsv python -m overflow.build_ribosome python -m overflow.analyze_usage -python -m overflow.run_sampling --procs 12 python -m overflow.compare ``` +Sampling uses the conventional GEM and no kcats, so it comes first: the kcats of the +respiratory chain are derived from its fluxes (above). + The tables and figures under `results/` are from a full run of this recipe. The models it builds (`models/ecModel_P_.yml`, about 67 MB) are not committed and rebuild in a few minutes. @@ -185,6 +238,13 @@ rebuild in a few minutes. Each step reads the models the previous one wrote, so `--models-dir` and `--results-dir` keep a run self-contained. +## Published datasets + +[`literature/xia2022/`](literature/xia2022/README.md) runs the analysis on nine +conditions of the glucose-limited chemostat series of Xia et al. (2022) and +compares them with `results/`, including each proteome's respiratory limit: +the highest glucose uptake it can respire completely. + ## Tests ```bash diff --git a/literature/xia2022/README.md b/literature/xia2022/README.md new file mode 100644 index 0000000..fcc789e --- /dev/null +++ b/literature/xia2022/README.md @@ -0,0 +1,75 @@ +# Glucose-limited chemostat series (Xia et al. 2022) + +The analysis of this repository run on nine conditions of the glucose-limited chemostat series of Xia et al. (2022), *Nat Commun* 13:2819, [doi:10.1038/s41467-022-30513-2](https://doi.org/10.1038/s41467-022-30513-2), and compared with the results of this study in `results/`. + +| Condition | D [1/h] | Ptot [g/gDW] | Ethanol [mmol/gDW/h] | +|---|---|---|---| +| mu003 | 0.027 | 0.299 | – | +| mu004 | 0.044 | 0.312 | – | +| mu010 | 0.10225 | 0.371 | – | +| mu015 | 0.152 | 0.419 | – | +| mu021 | 0.21425 | 0.320 | – | +| mu025 | 0.254 | 0.378 | – | +| mu028 | 0.28425 | 0.391 | – | +| mu033 | 0.33375 | 0.419 | 2.19 | +| mu038 | 0.3785 | 0.391 | 5.83 | + +How the data were converted is in [`data/README.md`](data/README.md). + +## Running + +`scripts/run_step.py [args]` points `overflow.config` at this folder's `data/`, condition names, `models/` and `results/`, then runs the step's `main`. For `build_ribosome` it supplies the core ribosome of `data/ribosome_core.tsv`. From the repository root, the recipe of this study: + +```bash +X=literature/xia2022 +O="--models-dir $X/models --results-dir $X/results" +python $X/scripts/run_step.py run_sampling --procs 12 --rate-tolerance 0.16 --results-dir $X/results +python $X/scripts/run_step.py respiratory_kcats --results-dir $X/results +python $X/scripts/run_step.py build --fit-rates --rate-tolerance 0.16 --uptake-flex 1.14 --block r_2129 --respiratory-kcats $X/results/modelGeneration/respiratoryKcats.tsv $O +python $X/scripts/run_step.py build_ribosome $O +python $X/scripts/run_step.py analyze_usage $O +``` + +The kcats of complex III, complex IV and ATP synthase are derived from this series, as they are from this study's data (see the repository README). `results/` keeps the outputs of this run that the comparison reads, and the sampled fluxes the kcats are derived from; the flux distributions of the built models, the ribosome tables and the pipeline's own usage figures are regenerated by the recipe and not committed, nor are the models (`models/`). + +### Departures from the recipe of this study + +- `--rate-tolerance 0.16` instead of 0.08, in the build and in sampling (0.05 in this study). Holding growth, glucose, CO2 and O2 together needs at least 15.4% at mu015, 12.7% at mu025 and 11.6% at mu010, even with protein unlimited. The measured O2 uptake of the series exceeds what complete oxidation of its measured glucose consumes by 7–46%, so the band has to absorb the difference. As in this study, the protein objective puts predicted glucose at the top of its band: 1.16× measured here, 1.08× there. +- `--uptake-flex 1.14` instead of 1.08: at 1.08× measured glucose mu015 and mu025 cannot reach their dilution rate. +- GAM is the model's (55.3), as in this study. Fitted on this series alone, with glucose fixed and O2 free, it would be about 35 (95% interval 22–48); this study's conditions without ethanol all grow at D = 0.1, so its data cannot fit one. One GAM keeps the ATP budgets of the two datasets comparable. At 55.3 the build's maintenance fit finds 0 for every condition but mu003 and mu004, and no non-negative value at mu010 and mu015; the rate band absorbs the difference. +- The core ribosome is fixed rather than re-selected; see [`data/README.md`](data/README.md#core-ribosome). +- `overflow.compare` is not run: it compares against the MATLAB results of this study's conditions only. +- `--block r_2129` applies to the ecModels. Sampling uses the conventional GEM, where the proton leak stays open, as in this study. + +The series attributes all of Ptot to measured proteins, while in this study the measured proteins add up to 72–83% of it. For the respiratory chain this difference in calibration cancels, because each dataset's kcats are derived from its own abundances. + +## Comparison with this study + +`comparison/` puts both datasets side by side. It needs the ecModels of both runs, so run this study's recipe first. + +```bash +for c in CN4 CN22 CN38 CN75 hGR; do for v in lifted measured; do python $X/comparison/respiratory_limit.py ThisStudy $c $v; done; done +for c in mu003 mu004 mu010 mu015 mu021 mu025 mu028 mu033 mu038; do for v in lifted measured; do python $X/comparison/respiratory_limit.py Xia $c $v; done; done +python $X/comparison/figures.py +``` + +`respiratory_limit.py` finds a condition's respiratory limit: the highest glucose uptake its measured proteome can respire completely at the condition's growth rate. Above it, the model has to secrete overflow carbon. The ecModel is held at the dilution rate with maintenance ATP free, so surplus glucose can be respired until a measured enzyme cap stops it. Caps the pipeline raised (minimum usage, relaxation to the dilution rate, the rate fit) show that the measurement understates what the condition needs, carry no capacity information and are lifted, for the whole complex. Unlisted exits are closed except glycine export, which levelled models need at some growth rates. As a conservative bound, the `measured` variant puts the caps the rate fit raised back to their measured abundance instead of lifting them (`lifted`). The limit is the largest uptake with no more than 0.05 mmol C/gDW/h of forced ethanol, acetate, glycerol and formate. Each run writes its curve and limit to `comparison/respiratory_limit/` (not committed); `figures.py` collects them into Table 5 and figure 5. A condition is predicted to overflow when its measured glucose uptake exceeds its limit; the onset of overflow itself is the measured physiology. As the respiratory-chain kcats are the highest apparent turnover within each dataset, the prediction is a consistency check rather than an independent test: the conditions that set the kcats run their respiratory chain at capacity. + +| Output (`comparison/`, figures as PDF) | Contents | +|---|---| +| `figures/fig1_capacity_usage` | Capacity usage of glycolysis, TCA cycle, ETC and ribosome, both datasets (`figS1`: the supplementary systems). | +| `figures/fig2_usage_vs_uptake` | Capacity usage per system (enzyme mass used over the measured capacity of its enzymes) against measured glucose uptake. | +| `figures/fig3_proteome_reserve` | Enzyme mass used in the simulation against the measured capacity, per system. | +| `figures/fig4_atp_budget` | Sampled ATP supply and demand, and the respiratory share of ATP. | +| `figures/fig5_respiratory_limit` | Least overflow the proteome allows against glucose uptake, with the respiratory limits (raised caps lifted) and the measured byproduct carbon. | +| `figures/fig6_apparent_turnover` | Apparent turnover of complex III, complex IV and ATP synthase relative to the highest in each dataset: sampled flux over measured complex, which needs no kcat. | +| `tables/tables.md` | Tables 1–7 (also as `table.tsv`): conditions and fit, capacity usage per system, enzyme mass used and measured capacity, ATP and redox budget, respiratory limit, the derived respiratory-chain kcats, and physiology with marker proteins. | + +### CN22 and μ0.28: what triggers overflow + +Both are the last condition of their series before ethanol, but they reach that point from opposite directions (Tables 3, 5 and 7). + +- **Ethanol: glucose uptake outgrows the respiratory capacity.** In this study glucose uptake rises with C/N while the TCA and ETC enzymes shrink with Ptot (TCA capacity 9.4, 7.2, 4.7 and 3.3 mg/gDW from CN4 to CN75). CN22 takes up 94% of a limit set by succinate dehydrogenase; CN38 is past its limit. In the Xia series the respiratory proteome grows with growth rate and peaks at μ0.28 (SDH1, CIT1, TCA capacity), which leaves it 27% below its limit. From μ0.33 the limit stops rising (5.06 at μ0.33 and μ0.38, set by complex IV) while glucose uptake keeps rising, and the surplus leaves as ethanol. +- **Formate follows nitrogen limitation, not respiratory saturation.** It is secreted at CN22, CN38 and CN75 and rises with C/N (0.05, 0.34 and 0.48 mmol/gDW/h), while hGR secretes the most ethanol of this study and no formate. A C1 imbalance would explain it: C1 units come from serine, made from glycolytic carbon that is in excess, while their main sink, the nitrogen-rich purines, shrinks with nitrogen (ribosome capacity 43 to 22 mg/gDW from CN4 to CN75). The glycine cleavage system, which releases ammonium from glycine and leaves a C1 unit, is 1.6–2.7 times higher in the conditions that secrete formate than at CN4 and hGR, and FDH1, which would oxidise formate to CO2, is not detected in this study. In the carbon-limited series the glycine cleavage system stays level and FDH1 is detected. + +Limits of this reading: Xia et al. do not report formate, so a C1 overflow at μ0.28 cannot be excluded; the glycine cleavage system does not scale with the amount of formate; and the model secretes formate only where the measured rate imposes it, so it cannot test the mechanism. The proteomics of the two datasets are calibrated differently, and Xia et al. do not detect several membrane proteins (GAP1, the hexose transporters), so protein levels are compared within each dataset. diff --git a/literature/xia2022/comparison/figures.py b/literature/xia2022/comparison/figures.py new file mode 100644 index 0000000..231f3ef --- /dev/null +++ b/literature/xia2022/comparison/figures.py @@ -0,0 +1,409 @@ +"""Figures and tables: this study next to the Xia et al. (2022) chemostat series.""" +from pathlib import Path + +import matplotlib +matplotlib.use("Agg") +import matplotlib.pyplot as plt +import numpy as np +import pandas as pd + +from overflow.plots import FONTS, LEGACY_COLOURS, capacity_usage_figure, _POINTS_PER_SIZE + +HERE = Path(__file__).resolve().parent +FIG, TAB, OUT = HERE / "figures", HERE / "tables", HERE / "respiratory_limit" +REPO = HERE.parents[2] +XIA = HERE.parent +SETS = { + "ThisStudy": dict(root=REPO, conds=["CN4", "CN22", "CN38", "CN75", "hGR"], + label="This study", colour=LEGACY_COLOURS[1], marker="o"), + "Xia": dict(root=XIA, conds=["mu003", "mu004", "mu010", "mu015", "mu021", "mu025", "mu028", "mu033", "mu038"], + label="Xia et al. 2022", colour=LEGACY_COLOURS[2], marker="^"), +} +DISPLAY = {c: f"μ{int(c[2:]) / 100:.2f}" for c in SETS["Xia"]["conds"]} +ORDER = [c for s in SETS.values() for c in s["conds"]] +#: bar positions, with a gap between the datasets +POSITIONS = np.concatenate([np.arange(len(ORDER))[:len(SETS["ThisStudy"]["conds"])], + np.arange(len(ORDER))[len(SETS["ThisStudy"]["conds"]):] + 0.6]) +SYSTEMS = ("Glycolysis", "TCA cycle", "ETC", "Ribosome") +SUPPLEMENT = ("PP shunt", "THF cycle", "Nitrogen metabolism", "Amino acid metabolism") +#: measured exchange (fermentationData.txt) -> modelled rate in the build summary +EXCHANGES = {"Glucose": "glucose", "CO2": "CO2", "Oxygen": "O2", "Ethanol": "ethanol"} +TEXT, SMALL, LINE = 7.0, 5.6, 0.15 * _POINTS_PER_SIZE +STYLE = {"font.family": FONTS, "pdf.fonttype": 42, "font.size": SMALL, "axes.linewidth": LINE, + "xtick.major.width": LINE, "ytick.major.width": LINE, "xtick.major.size": 2.75, + "ytick.major.size": 2.75, "axes.spines.top": False, "axes.spines.right": False, + "legend.frameon": False, "axes.labelsize": TEXT, "axes.titlesize": SMALL} + + +def name(c): + return DISPLAY.get(c, c) + + +def save(fig, stem): + fig.savefig(FIG / f"{stem}.pdf", facecolor="white") + plt.close(fig) + + +def read(dataset, *parts): + return pd.read_csv(SETS[dataset]["root"].joinpath(*parts), sep="\t") + + +def fermentation(): + rows = [] + for ds, s in SETS.items(): + f = read(ds, "data", "fermentationData.txt") + f.insert(0, "dataset", ds) + rows.append(f[f["Condition"].isin(s["conds"])]) + return pd.concat(rows).rename(columns={"Condition": "condition"}).set_index("condition") + + +FERM = fermentation() + + +def overflowing(c): + return pd.notna(FERM.loc[c, "Ethanol"]) and FERM.loc[c, "Ethanol"] > 0 + + +# ---------------------------------------------------------------- tables + +def table_conditions(): + rows = [] + for ds, s in SETS.items(): + summary = read(ds, "results", "modelGeneration", "summary.tsv").set_index("condition") + for c in s["conds"]: + gen = lambda kind: s["root"] / "results" / "modelGeneration" / f"{kind}_{c}.tsv" + relaxed = pd.read_csv(gen("relaxedEnzymes"), sep="\t") if gen("relaxedEnzymes").exists() else pd.DataFrame(columns=["added_mg_gDW"]) + row = dict(dataset=SETS[ds]["label"], condition=name(c), D=FERM.loc[c, "D"], Ptot=FERM.loc[c, "Ptot"]) + for ex, column in EXCHANGES.items(): + measured = FERM.loc[c, ex] + row[f"{ex} meas"] = 0.0 if pd.isna(measured) else measured + row[f"{ex} model"] = summary.loc[c, column] + row["caps raised to minimum"] = len(pd.read_csv(gen("minimumUsage"), sep="\t")) + row["caps relaxed for growth"] = len(pd.read_csv(gen("modifiedEnzymes"), sep="\t")) + row["caps relaxed for rates"] = len(relaxed) + row["mg/gDW added for rates"] = relaxed["added_mg_gDW"].sum() + rows.append(row) + return pd.DataFrame(rows) + + +def table_usage(r): + """Capacity usage per system: enzyme mass used over the measured capacity of its enzymes (%).""" + r = r.assign(usage=100 * r["used"] / r["cap"].where(r["cap"] > 0)) + wide = r.pivot(index="system", columns="condition", values="usage").reindex(list(SYSTEMS) + list(SUPPLEMENT))[ORDER] + return wide.rename(columns=DISPLAY).reset_index() + + +def selected_fluxes(): + k = read("ThisStudy", "results", "randomSampling", "selectedFluxes.tsv").set_index("Row") + x = read("Xia", "results", "randomSampling", "selectedFluxes.tsv").set_index("Row") + return k.join(x) + + +def table_atp(): + f = selected_fluxes() + rows = { + "glucose uptake": f.loc["rGlu"], + "ATP from ETC": f.loc["ETC_rATP"], + "ATP from glycolysis": f.loc["glycolysis_rATP"], + "ETC share of ATP supply (%)": 100 * f.loc["ETC_rATP"] / (f.loc["ETC_rATP"] + f.loc["glycolysis_rATP"]), + "ATP per glucose via ETC": f.loc["ETC_YATP_glu"], + "ATP for growth (GAEC)": f.loc["GAEC_rATP"], + "ATP not tied to growth (NGAM)": f.loc["NGAM_rATP"], + "ATP for other metabolism": f.loc["Metabolism_rATP"], + "pyruvate dehydrogenase": f.loc["rPDH"], + "isocitrate dehydrogenase (mito)": f.loc["rIDH"], + "external NADH dehydrogenase": f.loc["rNDE"], + "NADPH turnover (total)": f.loc["rNADP[tot]"], + } + return pd.DataFrame(rows).T[ORDER].rename(columns=DISPLAY).reset_index().rename(columns={"index": "flux (mmol/gDW/h)"}) + + +def system_mass(usage, conditions): + """Per system and condition: enzyme mass used and the measured cap of its enzymes, in mg/gDW.""" + annotation = read("ThisStudy", "data", "selectedAnnotation.txt") + system = dict(zip(annotation.iloc[:, 0], annotation.iloc[:, 3])) + usage = usage.assign(system=usage["protID"].map(system)) + rows = [] + for c in conditions: + measured = usage[usage[f"UB_{c}"] < 1000] # unmeasured enzymes draw on the pool, cap 1000 + for sysname, g in measured.groupby("system"): + rows.append(dict(condition=c, system=sysname, used=g[f"absUse_{c}"].sum(), cap=g[f"UB_{c}"].sum())) + return pd.DataFrame(rows) + + +def reserve(): + return pd.concat(system_mass(read(ds, "results", "enzymeUsage", "enzymeUsages.tsv"), s["conds"]).assign(dataset=ds) + for ds, s in SETS.items()) + + +def table_reserve(r): + """Enzyme mass used and measured capacity per system (mg/gDW), the numbers of figure 3.""" + r = r[r["system"].isin(SYSTEMS)].rename(columns={"used": "used", "cap": "measured capacity"}) + long = r.melt(id_vars=["system", "condition"], value_vars=["used", "measured capacity"], var_name="mg/gDW") + wide = long.pivot(index=["system", "mg/gDW"], columns="condition", values="value")[ORDER] + wide = wide.reindex(pd.MultiIndex.from_product([list(SYSTEMS), ["used", "measured capacity"]])) + return wide.rename(columns=DISPLAY).rename_axis(["system", "mg/gDW"]).reset_index() + + +#: proteins that tell nitrogen from carbon limitation, the C1 and TCA enzymes, and storage +MARKERS = {"GAP1": "P19145", "GLN1": "P32288", "GDH1": "P07262", "GCV1": "P48015", "GCV2": "P49095", + "SHM2": "P37291", "MTD1": "Q02046", "FDH1": "Q08911", "CIT1": "P00890", "SDH1": "Q00711", + "TPS1": "Q00764", "GSY2": "P27472"} +#: carbon per gram of biomass, CH1.8O0.5N0.2 at 24.6 g/C-mol +BIOMASS_C = 1000 / 24.6 +#: carbon atoms of the measured byproducts +CARBONS = {"CO2": 1, "Ethanol": 2, "Acetate": 2, "Glycerol": 3, "Formate": 1} + + +def table_physiology(): + """Yields and carbon balance from the measured rates, and marker proteins in ppm of the measured protein mass.""" + uniprot = read("ThisStudy", "data", "uniprot.tsv") + mass = dict(zip(uniprot["Entry"], uniprot["Mass"])) + rows = {} + for ds, s in SETS.items(): + prot = read(ds, "data", "abs_proteomics.txt").set_index("Protein.IDs") + prefix = {"hGR": "CN_hGR_"} if ds == "ThisStudy" else {} + for c in s["conds"]: + f = FERM.loc[c].fillna(0.0) + mean = prot[[k for k in prot if k.startswith(prefix.get(c, f"{c}_")) and k.endswith("_abs")]].mean(axis=1) + mg = mean * mean.index.map(mass).to_numpy(dtype=float) + row = { + "biomass yield (g/g glucose)": f["D"] / (f["Glucose"] * 0.18016), + "glucose per biomass (mmol/g)": f["Glucose"] / f["D"], + "O2 per glucose": f["Oxygen"] / f["Glucose"], + "RQ": f["CO2"] / f["Oxygen"], + # this study reads an empty rate as undetected; the Xia series does not report formate + "formate (mmol/gDW/h)": f["Formate"] if ds == "ThisStudy" else np.nan, + "carbon recovery": (sum(n * f[k] for k, n in CARBONS.items()) + BIOMASS_C * f["D"]) / (6 * f["Glucose"]), + } + row.update({f"{g} (ppm)": 1e6 * mg.get(u, np.nan) / mg.sum() for g, u in MARKERS.items()}) + rows[c] = row + return pd.DataFrame(rows)[ORDER].rename(columns=DISPLAY).reset_index().rename(columns={"index": "quantity"}) + + +def table_kcats(): + """The respiratory-chain kcats each dataset's build uses, against the ecModel's.""" + rows = [] + for ds, s in SETS.items(): + k = read(ds, "results", "modelGeneration", "respiratoryKcats.tsv") + k.insert(0, "dataset", s["label"]) + k["condition"] = k["condition"].map(name) + rows.append(k) + return pd.concat(rows).rename(columns={"condition": "set by", "kcat_per_s": "derived kcat (1/s)", + "ecmodel_kcat_per_s": "ecModel kcat (1/s)"}) + + +def limit_table(): + files = sorted(OUT.glob("limit_*.tsv")) + if not files: + return None + t = pd.concat(pd.read_csv(f, sep="\t") for f in files) + t["condition"] = pd.Categorical(t["condition"], ORDER, ordered=True) + return t.sort_values(["variant", "condition"]) + + +# ---------------------------------------------------------------- figures + +def figure_usage(systems, stem): + k = read("ThisStudy", "results", "enzymeUsage", "capUsage.tsv") + x = read("Xia", "results", "enzymeUsage", "capUsage.tsv") + both = k.drop(columns=["GOterm"]).merge(x[["protID", *SETS["Xia"]["conds"]]], on="protID", how="outer") + both["GOterm"] = both["protID"].map(dict(zip(pd.concat([k, x])["protID"], pd.concat([k, x])["GOterm"]))) + fig = capacity_usage_figure(both, systems=systems, conditions=ORDER, width=18 / 2.54, height=5 / 2.54) + for axis in fig.axes: + axis.axvline(5.5, color="#878787", linewidth=LINE, linestyle=(0, (2, 2))) + axis.set_xticklabels([name(c) for c in ORDER]) + fig.text(0.985, 0.97, "CN: this study μ: Xia et al. 2022", ha="right", va="top", fontsize=SMALL, color="#4D4D4D") + save(fig, stem) + + +def figure_trend(usage): + with plt.rc_context(STYLE): + fig, axes = plt.subplots(2, 4, figsize=(16 / 2.54, 8 / 2.54), sharex=True) + for axis, system in zip(axes.flat, list(SYSTEMS) + list(SUPPLEMENT)): + row = usage.set_index("system").loc[system] + for ds, s in SETS.items(): + xs = [FERM.loc[c, "Glucose"] for c in s["conds"]] + ys = [row[name(c)] for c in s["conds"]] + order = np.argsort(xs) + axis.plot(np.array(xs)[order], np.array(ys)[order], color=s["colour"], linewidth=0.6) + for c, xv, yv in zip(s["conds"], xs, ys): + axis.plot(xv, yv, s["marker"], markersize=3.5, color=s["colour"], + markerfacecolor=s["colour"] if overflowing(c) else "white", markeredgewidth=0.6) + axis.set_title(system, color="#1A1A1A") + axis.set_ylim(-5, 105) + axis.set_yticks([0, 50, 100]) + for axis in axes[1]: + axis.set_xlabel("Glucose uptake (mmol/gDW/h)", fontsize=SMALL) + for axis in axes[:, 0]: + axis.set_ylabel("Capacity usage (%)", fontsize=SMALL) + handles = [plt.Line2D([], [], color=s["colour"], marker=s["marker"], markersize=3.5, linewidth=0.6, label=s["label"]) for s in SETS.values()] + handles.append(plt.Line2D([], [], color="#4D4D4D", marker="o", markersize=3.5, linestyle="none", markerfacecolor="#4D4D4D", label="ethanol secreted")) + handles.append(plt.Line2D([], [], color="#4D4D4D", marker="o", markersize=3.5, linestyle="none", markerfacecolor="white", label="no ethanol")) + fig.legend(handles=handles, loc="lower center", ncol=4, fontsize=SMALL, bbox_to_anchor=(0.5, 0.045)) + fig.text(0.5, 0.005, "capacity usage: enzyme mass used over the measured capacity of the system's enzymes", + ha="center", va="bottom", fontsize=SMALL - 0.8, color="#4D4D4D") + fig.subplots_adjust(left=0.08, right=0.99, top=0.93, bottom=0.26, hspace=0.45, wspace=0.3) + save(fig, "fig2_usage_vs_uptake") + + +def figure_reserve(r): + with plt.rc_context(STYLE): + fig, axes = plt.subplots(1, 4, figsize=(16 / 2.54, 5.5 / 2.54)) + for index, (axis, system) in enumerate(zip(axes, SYSTEMS)): + sub = r[r["system"] == system].set_index("condition").loc[ORDER] + xs = POSITIONS + colour = LEGACY_COLOURS[index] + axis.bar(xs, sub["cap"], width=0.75, color="white", edgecolor=colour, linewidth=0.35 * _POINTS_PER_SIZE) + axis.bar(xs, sub["used"], width=0.75, color=colour, edgecolor=colour, linewidth=0.35 * _POINTS_PER_SIZE) + axis.set_xticks(xs) + axis.set_xticklabels([name(c) for c in ORDER], rotation=90) + axis.set_title(system, color="#1A1A1A") + axes[0].set_ylabel("Enzyme (mg/gDW)", fontsize=TEXT) + fig.text(0.99, 0.01, "filled: used in the simulation outline: measured capacity", ha="right", fontsize=SMALL, color="#4D4D4D") + fig.subplots_adjust(left=0.07, right=0.99, top=0.9, bottom=0.3, wspace=0.35) + save(fig, "fig3_proteome_reserve") + + +def figure_atp(): + f = selected_fluxes()[ORDER] + with plt.rc_context(STYLE): + fig, axes = plt.subplots(1, 3, figsize=(16 / 2.54, 5.5 / 2.54), gridspec_kw=dict(width_ratios=[1, 1, 0.9])) + xs = POSITIONS + labels = [name(c) for c in ORDER] + supply = [("ETC", f.loc["ETC_rATP"], LEGACY_COLOURS[2]), ("glycolysis", f.loc["glycolysis_rATP"], LEGACY_COLOURS[0])] + demand = [("growth (GAEC)", f.loc["GAEC_rATP"], LEGACY_COLOURS[1]), ("other metabolism", f.loc["Metabolism_rATP"], LEGACY_COLOURS[3]), + ("not tied to growth", f.loc["NGAM_rATP"], "#E6E0D4")] + for axis, parts, title in ((axes[0], supply, "ATP supply"), (axes[1], demand, "ATP demand")): + bottom = np.zeros(len(ORDER)) + for label, values, colour in parts: + axis.bar(xs, values.to_numpy(), bottom=bottom, width=0.75, color=colour, label=label, edgecolor="white", linewidth=0.2) + bottom += values.to_numpy() + axis.set_xticks(xs) + axis.set_xticklabels(labels, rotation=90) + axis.set_title(title, color="#1A1A1A") + axis.legend(fontsize=SMALL - 0.6, loc="upper left", handlelength=1) + axes[0].set_ylabel("ATP (mmol/gDW/h)", fontsize=TEXT) + axis = axes[2] + share = 100 * f.loc["ETC_rATP"] / (f.loc["ETC_rATP"] + f.loc["glycolysis_rATP"]) + for ds, s in SETS.items(): + xv = [FERM.loc[c, "Glucose"] for c in s["conds"]] + axis.plot(xv, share[s["conds"]], color=s["colour"], linewidth=0.6) + for c, x in zip(s["conds"], xv): + axis.plot(x, share[c], s["marker"], markersize=3.5, color=s["colour"], + markerfacecolor=s["colour"] if overflowing(c) else "white", markeredgewidth=0.6) + axis.set_xlabel("Glucose uptake (mmol/gDW/h)", fontsize=SMALL) + axis.set_ylabel("ATP from ETC (%)", fontsize=SMALL) + axis.set_title("Respiratory share", color="#1A1A1A") + axis.set_ylim(60, 100) + handles = [plt.Line2D([], [], color=s["colour"], marker=s["marker"], markersize=3.5, linewidth=0.6, label=s["label"]) for s in SETS.values()] + axis.legend(handles=handles, fontsize=SMALL - 0.6, loc="lower left") + fig.subplots_adjust(left=0.07, right=0.99, top=0.9, bottom=0.27, wspace=0.4) + save(fig, "fig4_atp_budget") + + +def figure_limit(limits, variant): + curves = pd.concat(pd.read_csv(f, sep="\t") for f in OUT.glob(f"curve_*_{variant}.tsv") if f.stat().st_size > 1) + with plt.rc_context(STYLE): + fig, axes = plt.subplots(1, 2, figsize=(14 / 2.54, 5.5 / 2.54), sharey=True) + xia = SETS["Xia"]["conds"] + blues = matplotlib.colors.LinearSegmentedColormap.from_list("xia", ["#6FA8DC", "#1D71B8", "#0B3B66"]) + palette = dict(zip(SETS["ThisStudy"]["conds"], ["#CBBBA0", "#A08F6E", "#6E5F45", "#1D1D1B", "#878787"])) + palette.update({c: matplotlib.colors.to_hex(blues(i / (len(xia) - 1))) for i, c in enumerate(xia)}) + limit = limits[limits["variant"] == variant].set_index("condition")["respiratory_limit"] + axes[0].axvspan(1.7, 2.3, color="#E6E0D4", linewidth=0, zorder=0) + axes[0].text(2.35, 13.5, "reported onset of overflow", ha="left", va="center", fontsize=SMALL - 0.6, color="#6E5F45") + for axis, (ds, s) in zip(axes, SETS.items()): + for c in s["conds"]: + cur = curves[(curves["dataset"] == ds) & (curves["condition"] == c)].sort_values("glucose") + axis.plot(cur["glucose"], cur["forced_overflow_C"], color=palette[c], linewidth=0.8, label=name(c)) + if np.isfinite(limit.get(c, np.nan)): + axis.plot(limit[c], -0.6, marker="^", markersize=3, color=palette[c], clip_on=False) + measured_c = sum(w * (0 if pd.isna(FERM.loc[c, ex]) else FERM.loc[c, ex]) + for ex, w in (("Ethanol", 2), ("Acetate", 2), ("Glycerol", 3), ("Formate", 1))) + axis.plot(FERM.loc[c, "Glucose"], measured_c, "o", markersize=3.5, color=palette[c], + markerfacecolor=palette[c] if overflowing(c) else "white", markeredgewidth=0.7) + axis.set_title(s["label"], color="#1A1A1A") + axis.set_xlabel("Glucose uptake (mmol/gDW/h)", fontsize=SMALL) + axis.set_xlim(0.2, 7.2) + axis.set_ylim(-1, 14) + axis.legend(fontsize=SMALL - 0.6, loc="upper left", handlelength=1.2) + axes[0].set_ylabel("Forced overflow (mmol C/gDW/h)", fontsize=SMALL) + fig.text(0.99, 0.01, "lines: least overflow the proteome allows at the condition's growth rate ▲: respiratory limit points: measured byproduct C", + ha="right", fontsize=SMALL - 0.6, color="#4D4D4D") + fig.subplots_adjust(left=0.09, right=0.99, top=0.9, bottom=0.25, wspace=0.12) + save(fig, "fig5_respiratory_limit") + + +def figure_turnover(): + """Apparent turnover of each complex relative to the highest in its dataset; needs no kcat.""" + complexes = ("complex III", "complex IV", "ATP synthase") + with plt.rc_context(STYLE): + fig, axes = plt.subplots(1, 3, figsize=(16 / 2.54, 5.5 / 2.54), sharey=True) + for axis, cx in zip(axes, complexes): + for ds, s in SETS.items(): + t = read(ds, "results", "modelGeneration", "respiratoryTurnover.tsv") + d = t[t["complex"] == cx].set_index("condition").loc[s["conds"]] + xs = [FERM.loc[c, "Glucose"] for c in s["conds"]] + axis.plot(xs, d["relative_to_highest"], color=s["colour"], linewidth=0.6) + for i, (c, x) in enumerate(zip(s["conds"], xs)): + y = d.loc[c, "relative_to_highest"] + axis.plot(x, y, s["marker"], markersize=3.5, color=s["colour"], + markerfacecolor=s["colour"] if overflowing(c) else "white", markeredgewidth=0.6) + # the Xia series is dense and its uptake rises with growth rate: label its ends and mu028 + if ds == "Xia" and 0 < i < len(xs) - 1 and c != "mu028": + continue + above = ds == "Xia" and c != "mu028" + axis.annotate(name(c), (x, y), xytext=(-2, 5) if above else (3, -8), textcoords="offset points", + ha="right" if above else "left", fontsize=SMALL - 1.4, color=s["colour"]) + axis.set_title(cx[0].upper() + cx[1:], color="#1A1A1A") + axis.set_ylim(0, 1.15) + axis.set_xlim(0, 7.2) + axis.set_xlabel("Glucose uptake (mmol/gDW/h)", fontsize=SMALL) + axes[0].set_ylabel("Apparent turnover / highest in dataset", fontsize=SMALL) + handles = [plt.Line2D([], [], color=s["colour"], marker=s["marker"], markersize=3.5, linewidth=0.6, label=s["label"]) + for s in SETS.values()] + handles += [plt.Line2D([], [], color="#4D4D4D", marker="o", markersize=3.5, linestyle="none", label="ethanol secreted"), + plt.Line2D([], [], color="#4D4D4D", marker="o", markersize=3.5, linestyle="none", markerfacecolor="white", + label="no ethanol")] + fig.legend(handles=handles, loc="lower center", ncol=4, fontsize=SMALL, bbox_to_anchor=(0.5, 0.0)) + fig.subplots_adjust(left=0.08, right=0.99, top=0.9, bottom=0.32, wspace=0.12) + save(fig, "fig6_apparent_turnover") + + +def markdown(tables): + lines = [] + for title, t in tables: + lines += [f"## {title}", "", t.to_markdown(index=False, floatfmt=".3g"), ""] + (TAB / "tables.md").write_text("\n".join(lines)) + + +if __name__ == "__main__": + FIG.mkdir(exist_ok=True) + TAB.mkdir(exist_ok=True) + r = reserve() + usage = table_usage(r) + tables = [ + ("Table 1. Conditions, measured and modelled exchange rates (mmol/gDW/h), and the caps the pipeline changed", table_conditions()), + ("Table 2. Capacity usage per system: enzyme mass used over the measured capacity of its enzymes (%)", usage), + ("Table 3. Enzyme mass used and measured capacity per system (mg/gDW)", table_reserve(r)), + ("Table 4. Sampled ATP and redox budget (mean over samples, mmol/gDW/h)", table_atp()), + ] + limits = limit_table() + if limits is not None: + tables.append(("Table 5. Respiratory limit: the highest glucose uptake the measured proteome can respire completely at the condition's growth rate (mmol/gDW/h)", + limits.replace({"dataset": {k: v["label"] for k, v in SETS.items()}}))) + tables.append(("Table 6. Respiratory-chain kcats derived from each dataset: the highest apparent turnover across its conditions", table_kcats())) + tables.append(("Table 7. Physiology from the measured rates and marker proteins (ppm of the measured protein mass; empty: not detected)", table_physiology())) + for i, (title, t) in enumerate(tables, 1): + t.to_csv(TAB / f"table{i}.tsv", sep="\t", index=False) + markdown(tables) + figure_usage(SYSTEMS, "fig1_capacity_usage") + figure_usage(SUPPLEMENT, "figS1_capacity_usage_supplement") + figure_trend(usage) + figure_reserve(r) + figure_atp() + if limits is not None: + figure_limit(limits, "lifted") + figure_turnover() + print(open(TAB / "tables.md").read()) diff --git a/literature/xia2022/comparison/figures/fig1_capacity_usage.pdf b/literature/xia2022/comparison/figures/fig1_capacity_usage.pdf new file mode 100644 index 0000000..2c5be53 Binary files /dev/null and b/literature/xia2022/comparison/figures/fig1_capacity_usage.pdf differ diff --git a/literature/xia2022/comparison/figures/fig2_usage_vs_uptake.pdf b/literature/xia2022/comparison/figures/fig2_usage_vs_uptake.pdf new file mode 100644 index 0000000..75e6014 Binary files /dev/null and b/literature/xia2022/comparison/figures/fig2_usage_vs_uptake.pdf differ diff --git a/literature/xia2022/comparison/figures/fig3_proteome_reserve.pdf b/literature/xia2022/comparison/figures/fig3_proteome_reserve.pdf new file mode 100644 index 0000000..556b335 Binary files /dev/null and b/literature/xia2022/comparison/figures/fig3_proteome_reserve.pdf differ diff --git a/literature/xia2022/comparison/figures/fig4_atp_budget.pdf b/literature/xia2022/comparison/figures/fig4_atp_budget.pdf new file mode 100644 index 0000000..c7ea55e Binary files /dev/null and b/literature/xia2022/comparison/figures/fig4_atp_budget.pdf differ diff --git a/literature/xia2022/comparison/figures/fig5_respiratory_limit.pdf b/literature/xia2022/comparison/figures/fig5_respiratory_limit.pdf new file mode 100644 index 0000000..06b3c14 Binary files /dev/null and b/literature/xia2022/comparison/figures/fig5_respiratory_limit.pdf differ diff --git a/literature/xia2022/comparison/figures/fig6_apparent_turnover.pdf b/literature/xia2022/comparison/figures/fig6_apparent_turnover.pdf new file mode 100644 index 0000000..45b7e90 Binary files /dev/null and b/literature/xia2022/comparison/figures/fig6_apparent_turnover.pdf differ diff --git a/literature/xia2022/comparison/figures/figS1_capacity_usage_supplement.pdf b/literature/xia2022/comparison/figures/figS1_capacity_usage_supplement.pdf new file mode 100644 index 0000000..39d38f3 Binary files /dev/null and b/literature/xia2022/comparison/figures/figS1_capacity_usage_supplement.pdf differ diff --git a/literature/xia2022/comparison/respiratory_limit.py b/literature/xia2022/comparison/respiratory_limit.py new file mode 100644 index 0000000..5dfabcf --- /dev/null +++ b/literature/xia2022/comparison/respiratory_limit.py @@ -0,0 +1,162 @@ +"""Respiratory limit: the highest glucose uptake a condition's measured proteome can respire completely. + +Each built ecModel is held at its dilution rate. Caps the pipeline raised +because the measurement could not support growth (raised to minimum, +flexibilized) are lifted, since they carry no capacity information. Two +variants for the caps the rate fit raised: lifted as well ("lifted"), or put +back to the measured abundance ("measured"). Maintenance ATP is free, so +surplus glucose can be respired without overflow until a measured enzyme cap +stops it; the respiratory limit is the largest uptake with no forced overflow. +""" +import sys +from pathlib import Path + +import numpy as np +import pandas as pd +import cobra + +cobra.Configuration().solver = "gurobi" +cobra.Configuration().processes = 1 + +import overflow.config as config +from geckopy import load_ec_model +from overflow import build_adapter +from overflow.complexes import complex_families +from overflow.config import BIO_RXN, C_SOURCE, CO2_RXN, NGAM_RXN, O2_RXN + +HERE = Path(__file__).resolve().parent +OUT = HERE / "respiratory_limit" +REPO = HERE.parents[2] +XIA = HERE.parent +DATASETS = { + "ThisStudy": (REPO, ("CN4", "CN22", "CN38", "CN75", "hGR")), + "Xia": (XIA, ("mu003", "mu004", "mu010", "mu015", "mu021", "mu025", "mu028", "mu033", "mu038")), +} +OVERFLOW = {"r_1761": 2, "r_1634": 2, "r_1808": 3, "r_1793": 1} # ethanol, acetate, glycerol, formate (C) +# glycine export (r_1810) stays open: every build secretes a little of it +OPEN = {CO2_RXN, "r_2100", "r_1832", "r_2111", "r_1810", *OVERFLOW} +THRESHOLD = 0.05 # mmol C/gDW/h of forced overflow tolerated at the limit + +uniprot = pd.read_csv(REPO / "data" / "uniprot.tsv", sep="\t") +GENE = dict(zip(uniprot["Entry"], uniprot["Gene Names (ordered locus)"])) +annotation = pd.read_csv(REPO / "data" / "selectedAnnotation.txt", sep="\t") +NAME = dict(zip(annotation.iloc[:, 0], annotation.iloc[:, 2])) +SYSTEM = dict(zip(annotation.iloc[:, 0], annotation.iloc[:, 3])) + + +def label(protein): + return f"{NAME.get(protein, GENE.get(protein, protein))} ({SYSTEM.get(protein, 'other')})" + + +def conditions(root, names): + config.CONDITION_ORDER = names + return config.load_conditions(root / "data" / "fermentationData.txt") + + +def prepare(model, cond, generation, variant): + for r in model.reactions: + if (len(r.metabolites) == 1 and r.id.startswith("r_") and r.id not in OPEN + and r.id not in (C_SOURCE, O2_RXN) and r.upper_bound > 0): + r.upper_bound = 0.001 + for rid in OVERFLOW: + model.reactions.get_by_id(rid).bounds = (0.0, 100.0) + model.reactions.get_by_id(CO2_RXN).bounds = (0.0, 1000.0) + model.reactions.get_by_id(O2_RXN).bounds = (-1000.0, 0.0) + model.reactions.get_by_id(NGAM_RXN).bounds = (0.0, 1000.0) + model.reactions.get_by_id(BIO_RXN).bounds = (0.99 * cond.d_rate, cond.d_rate) + + read = lambda kind: pd.read_csv(generation / f"{kind}_{cond.name}.tsv", sep="\t") + raised = set(read("minimumUsage")["protein"]) | set(read("modifiedEnzymes")["protein"]) + if variant == "lifted": + raised |= set(read("relaxedEnzymes")["protein"]) + # a complex is lifted as a whole when any of its subunits was raised + families = complex_families(model) + no_information = {m for p in raised for m in families.members(p)} + for p in no_information: + rid = f"usage_prot_{p}" + if rid in model.reactions: + model.reactions.get_by_id(rid).upper_bound = 1000.0 + restored = 0 + if variant == "measured": + relaxed_path = generation / f"relaxedEnzymes_{cond.name}.tsv" + if relaxed_path.exists(): + for p, measured in pd.read_csv(relaxed_path, sep="\t")[["protein", "measured_mg_gDW"]].itertuples(index=False): + rid = f"usage_prot_{p}" + if p not in no_information and rid in model.reactions: + model.reactions.get_by_id(rid).upper_bound = float(measured) + restored += 1 + return len(no_information), restored + + +def overflow_expression(model): + return sum(w * model.reactions.get_by_id(r).flux_expression for r, w in OVERFLOW.items()) + + +def limiting(model, uptake): + """Measured caps that bind when overflow is minimised just past the limit.""" + glc = model.reactions.get_by_id(C_SOURCE) + with model: + glc.bounds = (-uptake, -uptake) + model.objective = model.problem.Objective(overflow_expression(model), direction="min") + sol = model.optimize() + if sol.status != "optimal": + return [] + hits = [] + for r in model.reactions: + if r.id.startswith("usage_prot_") and r.upper_bound < 1000: + if sol.fluxes[r.id] >= r.upper_bound - 1e-9 and abs(sol.reduced_costs[r.id]) > 1e-6: + hits.append((abs(sol.reduced_costs[r.id]), r.id.removeprefix("usage_prot_"))) + return [p for _, p in sorted(hits, reverse=True)[:3]] + + +def run(dataset, root, cond, variant): + model = load_ec_model(str(root / "models" / f"ecModel_P_{cond.name}.yml"), adapter=build_adapter(cond)) + lifted, restored = prepare(model, cond, root / "results" / "modelGeneration", variant) + glc = model.reactions.get_by_id(C_SOURCE) + + window = [] + for direction in ("max", "min"): # uptake is negative flux + with model: + glc.bounds = (-50.0, 0.0) + model.objective = {glc: 1.0} + model.objective.direction = direction + window.append(-model.slim_optimize(error_value=float("nan"))) + umin, umax = window + row = dict(dataset=dataset, variant=variant, condition=cond.name, D=cond.d_rate, + glucose_measured=cond.glucose, ethanol_measured=cond.byproducts.get("Ethanol", 0.0), + caps_lifted=lifted, caps_restored=restored, uptake_min=umin, uptake_max=umax) + curve = [] + if not np.isfinite(umin): + row.update(respiratory_limit=float("nan"), limiting="infeasible") + return row, curve + + with model: + glc.bounds = (-50.0, 0.0) + model.add_cons_vars(model.problem.Constraint(overflow_expression(model), ub=THRESHOLD, name="no_overflow")) + model.objective = {glc: 1.0} + model.objective.direction = "min" + limit = -model.slim_optimize(error_value=float("nan")) + hits = limiting(model, min(limit * 1.02, umax)) if np.isfinite(limit) and limit < umax - 1e-6 else [] + row.update(respiratory_limit=limit, limiting="; ".join(label(p) for p in hits) or "none (window end)") + + for u in np.linspace(umin, min(umax, 3.0 * max(limit, cond.glucose)), 30): + with model: + glc.bounds = (-u, -u) + model.objective = model.problem.Objective(overflow_expression(model), direction="min") + sol = model.optimize() + if sol.status == "optimal": + curve.append(dict(dataset=dataset, variant=variant, condition=cond.name, glucose=u, + forced_overflow_C=sol.objective_value, + ethanol=sol.fluxes["r_1761"], CO2=sol.fluxes[CO2_RXN], O2=-sol.fluxes[O2_RXN])) + return row, curve + + +if __name__ == "__main__": + dataset, name, variant = sys.argv[1:4] + root, names = DATASETS[dataset] + cond = conditions(root, names)[name] + row, curve = run(dataset, root, cond, variant) + OUT.mkdir(exist_ok=True) + pd.DataFrame([row]).to_csv(OUT / f"limit_{dataset}_{name}_{variant}.tsv", sep="\t", index=False) + pd.DataFrame(curve).to_csv(OUT / f"curve_{dataset}_{name}_{variant}.tsv", sep="\t", index=False) + print(pd.DataFrame([row]).T.to_string()) diff --git a/literature/xia2022/comparison/tables/table1.tsv b/literature/xia2022/comparison/tables/table1.tsv new file mode 100644 index 0000000..09c7eaf --- /dev/null +++ b/literature/xia2022/comparison/tables/table1.tsv @@ -0,0 +1,15 @@ +dataset condition D Ptot Glucose meas Glucose model CO2 meas CO2 model Oxygen meas Oxygen model Ethanol meas Ethanol model caps raised to minimum caps relaxed for growth caps relaxed for rates mg/gDW added for rates +This study CN4 0.1 0.5 1.115503298 1.2047 3.087765343 3.1013 2.928264928 2.7301 0.0 0.0 9 12 0 0.0 +This study CN22 0.1 0.55 1.477902724 1.5961 4.069756802 4.3953 4.18530233 3.8505 0.0 0.0 11 5 3 0.2987830290682203 +This study CN38 0.1 0.33 2.013614504 2.1747 6.303284138 5.799 5.168723262 4.9542 0.790476913 0.7467 18 8 15 5.420346938292289 +This study CN75 0.1 0.27 3.227279363 3.4855 7.880181174 8.5106 6.66106775 6.1282 2.282585358 2.1 18 9 19 8.011230685024943 +This study hGR 0.29 0.41 5.415584674 5.8488 11.03323855 11.9159 7.659524146 7.5735 3.680414594 3.386 24 16 8 1.191255958260105 +Xia et al. 2022 μ0.03 0.027 0.299 0.325917121149714 0.3781 0.9570207835601432 0.9722 0.840845047999322 0.8265 0.0 0.0 7 0 0 0.0 +Xia et al. 2022 μ0.04 0.044 0.312 0.494144704652056 0.5732 1.5648471138116322 1.6231 1.54277114377377 1.4596 0.0 0.0 8 0 0 0.0 +Xia et al. 2022 μ0.10 0.10225 0.371 1.1441811165618 1.3273 2.68608596738391 3.1159 2.42077135288014 2.8081 0.0 0.0 11 3 5 0.7521405454151459 +Xia et al. 2022 μ0.15 0.152 0.419 1.60320845720337 1.8597 3.8796884681049018 4.5004 4.05760576525164 4.0802 0.0 0.0 14 11 7 0.9657422019345068 +Xia et al. 2022 μ0.21 0.21425 0.32 2.37362494155752 2.7534 5.923104157760982 6.8708 5.62833319678978 6.3749 0.0 0.0 16 13 5 0.860358878417707 +Xia et al. 2022 μ0.25 0.254 0.378 2.71217025984321 3.1461 6.813127576101639 7.9032 5.90540962542369 6.8503 0.0 0.01 19 14 7 0.5015222049609429 +Xia et al. 2022 μ0.28 0.28425 0.391 3.14269663461493 3.6455 8.540704142263435 9.803 7.98407343919044 8.6654 0.0 0.0 26 15 0 0.0 +Xia et al. 2022 μ0.33 0.33375 0.419 4.88134659826695 5.6624 12.239522291088242 13.0553 9.64295113005445 9.1107 2.193290332967266 1.8424 29 15 7 0.21975134839196891 +Xia et al. 2022 μ0.38 0.3784999999999999 0.391 6.70691099812471 7.78 14.385452880294718 16.6871 9.5922636191899 9.6094 5.831389975022448 4.8984 28 17 9 1.2024934282463449 diff --git a/literature/xia2022/comparison/tables/table2.tsv b/literature/xia2022/comparison/tables/table2.tsv new file mode 100644 index 0000000..6f04872 --- /dev/null +++ b/literature/xia2022/comparison/tables/table2.tsv @@ -0,0 +1,9 @@ +system CN4 CN22 CN38 CN75 hGR μ0.03 μ0.04 μ0.10 μ0.15 μ0.21 μ0.25 μ0.28 μ0.33 μ0.38 +Glycolysis 2.3358211917995395 2.7431827486958795 6.133648434142673 9.37473833908617 13.803186956647055 1.1797112457059358 1.8044688839013356 4.312286633979418 6.428405885988231 20.127818379259672 27.780737560835828 28.961927603812555 41.713018939459246 51.46075777043214 +TCA cycle 9.195709534101464 18.646624031421368 33.29480006780679 50.51767906033358 25.81524521351393 3.958277839005868 6.845097170743651 10.151188539367515 11.628004770113915 21.66527092770251 17.94983076206099 19.648198518590032 21.601394003630645 26.245836997796804 +ETC 19.651221658994768 30.504018776163914 45.19980133053849 86.3742052376914 68.20476293557294 13.39311987196794 22.90411015486909 34.03586480624735 37.33411959680475 71.39980789548893 61.07196668547512 67.31187736251526 67.01922684912297 83.18327871938291 +Ribosome 26.775181139918892 29.491256823620965 46.1327191653573 52.75523614250961 70.29997494483561 14.563449117189547 21.478095051982276 35.45214664824225 41.00210034698537 65.16505904544391 63.09504685745619 64.7473465826136 64.8850701448007 70.7815564935459 +PP shunt 11.012247254301405 1.6491614834638297 1.319309338409253 1.44496544854789 4.3328613193013705 3.0122965664041295 2.9764815674087184 5.891618776541861 17.08531841821738 9.875021661204569 12.294564344620088 8.714064842967899 7.1992346123325435 10.001099451525494 +THF cycle 19.20042857341681 86.99206302669313 68.53608305709902 97.83555472090823 55.63410150033473 5.952372322039658 9.170966490204256 14.677343174648067 17.092923464109163 25.839892740460787 31.108893508690095 36.501347319852044 35.62800930514156 39.14874610764992 +Nitrogen metabolism 0.0 2.4850665247796475 0.0 0.0 0.0 +Amino acid metabolism 10.43711170483253 12.349402344947624 21.396235789494508 30.71677271573961 24.60975214135818 5.607577834866893 7.518437195785973 12.115373583455666 14.201716114114102 23.67175912245717 23.942383906271854 23.98265952773618 26.572943396513583 29.114676936213364 diff --git a/literature/xia2022/comparison/tables/table3.tsv b/literature/xia2022/comparison/tables/table3.tsv new file mode 100644 index 0000000..0c32769 --- /dev/null +++ b/literature/xia2022/comparison/tables/table3.tsv @@ -0,0 +1,9 @@ +system mg/gDW CN4 CN22 CN38 CN75 hGR μ0.03 μ0.04 μ0.10 μ0.15 μ0.21 μ0.25 μ0.28 μ0.33 μ0.38 +Glycolysis used 1.5912107063641987 2.0207394162798473 2.848943872298771 3.7089251607673024 5.214238876347631 0.5064070770737548 0.7765569168143593 1.6925407418547498 2.5332677958041905 5.12115989814149 7.472271900240009 8.398653115078739 14.393741086263992 20.238054963538058 +Glycolysis measured capacity 68.12211105672495 73.66404652553736 46.447785569845436 39.56297260376486 37.77561582498645 42.92635837091832 43.035206854629244 39.249263453827 39.40740271745853 25.443194099060886 26.897312873269854 28.99894382020739 34.506591592314486 39.327160812167946 +TCA cycle used 0.8647411634842228 1.3368169401697625 1.5567320484204916 1.6635872718230003 2.164025381912357 0.2580209555523366 0.4839699078247313 0.9034371533338329 1.279935401898789 2.1167406389078574 2.200121111062944 2.910256927166148 2.8285913814299866 2.887447025951213 +TCA cycle measured capacity 9.403745956496426 7.169217000981499 4.675601130657389 3.293079378876784 8.382741918637748 6.518515527377413 7.070314646419444 8.899816507497583 11.007351881970806 9.770201563467484 12.257057686098914 14.81182574785482 13.094485388093805 11.001542934956117 +ETC used 0.4554569935159403 0.6450358155300767 0.8268759977039383 1.0314511807896587 1.2618394210853685 0.44409741824619936 0.7854133610528719 1.5058866681185936 2.187176789535958 3.4030730238289713 3.669487263463204 4.644080148155331 4.854591684254951 5.139079180526123 +ETC measured capacity 2.3177032014570367 2.114592900900366 1.8293797170857768 1.1941657557962233 1.8500752246251742 3.315862341945463 3.4291371973946956 4.424411357522447 5.858385876395886 4.766221540554003 6.0084642146229195 6.899347232798373 7.243580555150017 6.1780195006050445 +Ribosome used 11.598488801409431 11.598488801409431 11.598488801409431 11.598488801409431 33.635617524087344 3.0930795824995054 5.0405741344436406 11.71360693742869 17.412892464441676 24.544159279648873 29.09785977610648 32.56325449353648 38.23390039478558 43.36039340652086 +Ribosome measured capacity 43.31805914140891 39.328567347186244 25.14156765794796 21.985474143415864 47.84584567843902 21.238647229856273 23.468441322399453 33.040614024452765 42.46829386076056 37.6646006911965 46.11750244332828 50.29280150034842 58.92557457279608 61.259451691309735 diff --git a/literature/xia2022/comparison/tables/table4.tsv b/literature/xia2022/comparison/tables/table4.tsv new file mode 100644 index 0000000..9d459a1 --- /dev/null +++ b/literature/xia2022/comparison/tables/table4.tsv @@ -0,0 +1,13 @@ +flux (mmol/gDW/h) CN4 CN22 CN38 CN75 hGR μ0.03 μ0.04 μ0.10 μ0.15 μ0.21 μ0.25 μ0.28 μ0.33 μ0.38 +glucose uptake 1.1710002739394922 1.542789959749022 2.114276052770183 3.3697276245632835 5.657428314487561 0.3730299360838871 0.5695554500263653 1.3101497120401149 1.8564468044982183 2.705567238071132 3.128006167774593 3.593461172180393 5.565805480213094 7.674218123681864 +ATP from ETC 8.183851697320797 12.18869430495205 14.551048196767 18.964735912058128 21.986648448262272 2.789755094146721 5.022169681862444 7.8419754984552625 13.163065654703033 18.07693299815211 19.503244035170667 25.90639154011047 31.53082595432204 30.270244771483306 +ATP from glycolysis 1.2249609731065 1.9375423713543949 2.302117917092304 4.531740352838078 7.642297360152796 0.4223651728031219 0.5944638062383629 1.4536809948275446 2.025394280672023 2.7777173651650555 3.467492680450629 3.9636394614778654 7.418725954677164 10.936766014043652 +ETC share of ATP supply (%) 86.98070611016992 86.2840867263382 86.3401458127257 80.71310650266095 74.20665112566283 86.85089169453202 89.4160121450372 84.36171779929693 86.66491343237026 86.68058530460432 84.9047389146533 86.73038048983913 80.95298766976808 73.4589677689386 +ATP per glucose via ETC 6.988770096345573 7.900423662942998 6.8822839750286215 5.627972947669905 3.886332663192354 7.478635959981935 8.81770103618526 5.985556785143309 7.090462071312027 6.681383757085858 6.235040146690685 7.20931444610304 5.665096645295415 3.9444076625959297 +ATP for growth (GAEC) 5.53401553085298 5.658308741357577 5.135770805491181 5.004800621382446 15.437196374826287 1.209487861919706 1.982426767367212 4.729874282258439 7.183773767055699 9.685185071107153 11.7875505587985 13.274042899136267 15.784796512706087 17.6760797718252 +ATP not tied to growth (NGAM) 0.8189617699735287 4.489432893052654 8.566448185382107 14.673368533551171 4.823761963054999 1.402644910835488 2.5532822293319803 2.15732013678463 3.1869246918126346 6.362718403456992 5.198535744544199 9.563804267398806 14.51548224843692 13.94432242255514 +ATP for other metabolism 3.0558353696007887 3.978495041896214 3.150947122986014 3.8183071099625874 9.367987470533782 0.5999874941946493 1.0809244914016145 2.4084620742397376 4.817761476506719 4.806746888753024 5.984650412278598 7.032183835053262 8.649273147856189 9.586608591146614 +pyruvate dehydrogenase 1.045588865028507 1.5781012632176867 1.7666692904934282 2.597970997252705 3.731839463537647 0.3373382673341216 0.6230043196500415 1.033248283606257 1.6675365633096388 2.4771614139187745 2.422516669873273 3.436177962702028 3.9562532535285646 4.3372378907576365 +isocitrate dehydrogenase (mito) 0.7953203955814766 1.106565689035396 1.403593430867607 1.563562929037139 1.067245799855897 0.2935851269145126 0.6028683332763447 0.6410873738221198 1.4014670330075096 1.6483403291905931 1.773424407220941 2.3331633169581925 3.11572311831835 2.117527554380613 +external NADH dehydrogenase 1.8012114342249017 2.5902246323924696 3.054302242846611 4.343613334006659 5.892381716231975 0.5128320889858105 0.8484656326356158 1.8001047749673145 2.7574209674541192 3.7157945884653576 4.294989162640974 5.127009468168347 6.490125298075176 12.81145094033337 +NADPH turnover (total) 1.6435015870862373 1.8748530646551704 1.680062100912789 2.006716435285049 5.178473384570827 0.3260993229375902 0.6608498040485213 1.408422835685016 2.3585253211176056 3.3465988266032185 3.107963886395941 4.239632991589242 5.181305305966212 6.382527177185226 diff --git a/literature/xia2022/comparison/tables/table5.tsv b/literature/xia2022/comparison/tables/table5.tsv new file mode 100644 index 0000000..8d81581 --- /dev/null +++ b/literature/xia2022/comparison/tables/table5.tsv @@ -0,0 +1,29 @@ +dataset variant condition D glucose_measured ethanol_measured caps_lifted caps_restored uptake_min uptake_max respiratory_limit limiting +This study lifted CN4 0.1 1.115503298 0.0 20 0 1.1831510518937036 17.69883075336434 1.9526235248614248 SDH3 (TCA cycle); RPE1 (PP shunt); YJR073C (other) +This study lifted CN22 0.1 1.477902724 0.0 17 0 1.3674449588210194 16.80565581108385 1.5663525930958473 SDH3 (TCA cycle); RKI1 (PP shunt); YPR021C (other) +This study lifted CN38 0.1 2.013614504 0.790476913 34 0 1.2437591660603915 12.25192831924222 2.128420318673033 IDP2 (TCA cycle); KGD2 (TCA cycle); SOL3 (PP shunt) +This study lifted CN75 0.1 3.227279363 2.282585358 38 0 1.249496443050924 10.889507306682116 2.1919431934663285 COX9 (ETC); YGL001C (other); SOL3 (PP shunt) +This study lifted hGR 0.29 5.415584674 3.680414594 36 0 3.4597741252385665 16.009544736783052 3.936196275440714 COX3 (ETC); GLY1 (Amino acid metabolism); YIL160C (other) +Xia et al. 2022 lifted mu003 0.027 0.325917121149714 0.0 7 0 0.3175703760857291 7.424460214453545 1.1407216324672682 YJR048W (other); YEL039C (other); YBR041W (other) +Xia et al. 2022 lifted mu004 0.044 0.494144704652056 0.0 8 0 0.5186057848557114 8.309360736271959 1.4403619860986252 YJR048W (other); YEL039C (other); YBR041W (other) +Xia et al. 2022 lifted mu010 0.10225 1.1441811165618 0.0 17 0 1.232180622191682 6.931315824704769 2.0922488481325208 YBR041W (other); COX1 (ETC); GLY1 (Amino acid metabolism) +Xia et al. 2022 lifted mu015 0.152 1.60320845720337 0.0 22 0 1.7878256609784702 6.972108594284817 3.226142773450094 COB (ETC); GLY1 (Amino acid metabolism); YHR190W (other) +Xia et al. 2022 lifted mu021 0.21425 2.37362494155752 0.0 25 0 2.5613981847119267 4.356624843423074 3.2973899654635965 COX2 (ETC); YBR041W (other); YLR231C (other) +Xia et al. 2022 lifted mu025 0.254 2.71217025984321 0.0 30 0 2.989463952186916 3.910934411428705 3.877168531556478 RPE1 (PP shunt); TDH1 (Glycolysis); TYR1 (Amino acid metabolism) +Xia et al. 2022 lifted mu028 0.28425 3.14269663461493 0.0 36 0 3.399905042616924 4.357896278917606 4.318651135891623 RPE1 (PP shunt); TDH1 (Glycolysis); TYR1 (Amino acid metabolism) +Xia et al. 2022 lifted mu033 0.33375 4.88134659826695 2.193290332967266 41 0 3.974876661035077 15.717893402685188 5.062808981978785 COX1 (ETC); GLY1 (Amino acid metabolism); YIL160C (other) +Xia et al. 2022 lifted mu038 0.3784999999999999 6.70691099812471 5.831389975022448 41 0 4.514825268021467 15.596508248227344 5.0585833249602485 COX2 (ETC); GLY1 (Amino acid metabolism); TRP4 (Amino acid metabolism) +This study measured CN4 0.1 1.115503298 0.0 20 0 1.1831510518937036 17.69883075336434 1.9526235248614248 SDH3 (TCA cycle); RPE1 (PP shunt); YJR073C (other) +This study measured CN22 0.1 1.477902724 0.0 16 1 1.3674449588210194 16.80565581108385 1.558167897665972 SDH3 (TCA cycle); RKI1 (PP shunt); YPR021C (other) +This study measured CN38 0.1 2.013614504 0.790476913 22 12 1.5286852495796253 12.25192831924223 none (window end) +This study measured CN75 0.1 3.227279363 2.282585358 22 16 1.7465878518895068 10.889507306682102 none (window end) +This study measured hGR 0.29 5.415584674 3.680414594 35 1 3.833094012253931 16.009544736783056 none (window end) +Xia et al. 2022 measured mu003 0.027 0.325917121149714 0.0 7 0 0.3175703760857291 7.424460214453545 1.1407216324672682 YJR048W (other); YEL039C (other); YBR041W (other) +Xia et al. 2022 measured mu004 0.044 0.494144704652056 0.0 8 0 0.5186057848557114 8.309360736271959 1.4403619860986252 YJR048W (other); YEL039C (other); YBR041W (other) +Xia et al. 2022 measured mu010 0.10225 1.1441811165618 0.0 13 4 1.2370295580369035 6.931315824704767 2.0922488481325185 COX3 (ETC); YBR041W (other); GLY1 (Amino acid metabolism) +Xia et al. 2022 measured mu015 0.152 1.60320845720337 0.0 22 0 1.7878256609784702 6.972108594284817 3.226142773450094 COB (ETC); GLY1 (Amino acid metabolism); YHR190W (other) +Xia et al. 2022 measured mu021 0.21425 2.37362494155752 0.0 25 0 2.5613981847119267 4.356624843423074 3.2973899654635965 COX2 (ETC); YBR041W (other); YLR231C (other) +Xia et al. 2022 measured mu025 0.254 2.71217025984321 0.0 29 1 2.993731919443582 3.910934411428737 3.877168531556509 RPE1 (PP shunt); TDH1 (Glycolysis); TYR1 (Amino acid metabolism) +Xia et al. 2022 measured mu028 0.28425 3.14269663461493 0.0 36 0 3.399905042616924 4.357896278917606 4.318651135891623 RPE1 (PP shunt); TDH1 (Glycolysis); TYR1 (Amino acid metabolism) +Xia et al. 2022 measured mu033 0.33375 4.88134659826695 2.193290332967266 40 1 4.361734273737014 14.871493953423752 none (window end) +Xia et al. 2022 measured mu038 0.3784999999999999 6.70691099812471 5.831389975022448 40 1 4.51482526802152 15.59650824822737 5.058583324960227 COX2 (ETC); GLY1 (Amino acid metabolism); TRP4 (Amino acid metabolism) diff --git a/literature/xia2022/comparison/tables/table6.tsv b/literature/xia2022/comparison/tables/table6.tsv new file mode 100644 index 0000000..065b65a --- /dev/null +++ b/literature/xia2022/comparison/tables/table6.tsv @@ -0,0 +1,7 @@ +dataset complex reaction set by derived kcat (1/s) ecModel kcat (1/s) +This study ATP synthase r_0226 CN75 1607.695903 84.649052 +This study complex III r_0439 CN75 1452.134199 290.494288 +This study complex IV r_0438 CN75 3242.055529 1376.34631 +Xia et al. 2022 ATP synthase r_0226 μ0.38 447.037089 84.649052 +Xia et al. 2022 complex III r_0439 μ0.38 426.978118 290.494288 +Xia et al. 2022 complex IV r_0438 μ0.38 1090.333553 1376.34631 diff --git a/literature/xia2022/comparison/tables/table7.tsv b/literature/xia2022/comparison/tables/table7.tsv new file mode 100644 index 0000000..a12e236 --- /dev/null +++ b/literature/xia2022/comparison/tables/table7.tsv @@ -0,0 +1,19 @@ +quantity CN4 CN22 CN38 CN75 hGR μ0.03 μ0.04 μ0.10 μ0.15 μ0.21 μ0.25 μ0.28 μ0.33 μ0.38 +biomass yield (g/g glucose) 0.4975889967854671 0.37557422281515457 0.27565463293002773 0.17199074035125603 0.29723111743037434 0.45983096730621226 0.49424257947994543 0.49603254021952364 0.5262537694287371 0.5010145755956054 0.5198264743772986 0.5020415245344849 0.379510027600933 0.3132455913819707 +glucose per biomass (mmol/g) 11.155032979999998 14.77902724 20.13614504 32.272793629999995 18.674429910344827 12.071004487026444 11.23056146936491 11.190035369797556 10.547424060548487 11.078762854410828 10.677835668674055 11.056100737431592 14.625757597803597 17.719712016181536 +O2 per glucose 2.625061649974611 2.8319200323769076 2.5668881763279154 2.0639885800924387 1.4143485158256432 2.579935184236822 3.122103969241332 2.1157239162925725 2.53092836868495 2.3711973607323964 2.1773742278868142 2.5405167496126198 1.9754694603079481 1.4302058908895543 +RQ 1.0544692570248206 0.9723925492378945 1.2195050534705916 1.1830207212649952 1.440460052046685 1.1381654513364212 1.0143092967009109 1.1095992044800551 0.956152147980866 1.0523726919968652 1.153709566017247 1.0697176331496063 1.2692714217892267 1.4996932373205167 +formate (mmol/gDW/h) 0.0 0.048607541 0.343516274 0.479663775 0.0 +carbon recovery 1.0686963762203217 0.9228623847061922 1.0766398305606781 0.9419081631889964 0.9704016950549382 1.0506667829754293 1.131067130882839 0.9967230323619507 1.0456687870219197 1.027433715065323 1.0531744683023037 1.0657292408109578 1.0309032395034232 1.0296446879871008 +GAP1 (ppm) 1895.5319370339257 1618.3830654077017 1422.974013577254 +GLN1 (ppm) 358.5488265357396 2803.3827583426264 2519.340186300723 2460.6814785167553 940.0212550965645 303.3462422214787 402.7009101319362 647.3625006223817 815.3122249985436 1002.0178120889864 1055.8196452111063 1137.8129710764385 1281.6223107877906 1283.397549023595 +GDH1 (ppm) 2898.9187519479337 9719.422981662105 9763.904128923503 9001.627077583838 6001.27469678653 1280.8537545833622 2102.4628850978456 4489.6506220879555 5694.691265637316 7091.24442282249 7123.558608863212 6457.969210218877 6260.989429097291 6467.978445553832 +GCV1 (ppm) 293.41075092939303 705.2178676685772 537.0291555721404 542.844347523042 274.84877422656626 374.79228563937176 381.6122764464345 464.02789261202423 484.7238971121356 458.3849696886522 449.1375423876882 426.0093941046633 447.75508112263253 463.6271927467788 +GCV2 (ppm) 200.43209512416016 534.9864490982625 429.56514882091824 439.4206580872987 307.6348723509111 259.47821098342484 388.2629187992393 626.0498014881598 681.3206381670714 676.3971456347762 651.8403715589496 578.5972656355417 565.1314889651838 604.1424884495362 +SHM2 (ppm) 3178.7613353137863 3115.044936150883 3331.279050792347 3851.519579695673 5452.936083468783 2564.4512450203165 2945.293218436364 3597.93335168061 3984.8812400541333 4319.467055932743 4562.909488994017 4960.5699388437415 5895.362720317361 6584.211282423897 +MTD1 (ppm) 203.84049064043032 225.77165845486027 236.59283809575297 251.93226395687145 243.98686013057917 237.21275778118235 265.3522600138226 297.20976750936603 316.80485987352324 312.714731893815 304.51459082600536 289.4486371789658 328.1952930691836 358.77538643582466 +FDH1 (ppm) 1546.094903738397 1714.2104582833942 755.051581818378 504.7630641603071 353.27154514037653 220.85033380530038 83.072876048251 163.81951979459558 108.18021438315485 +CIT1 (ppm) 3682.5196961924285 2419.541601651783 2139.173470995523 1633.2965672553846 5431.753661670089 2852.1297559921877 2841.952895738573 2958.4787285846073 3279.0836579592883 4013.6040790404995 4955.069894419456 6094.297464360867 5042.545800163649 3764.0494739041246 +SDH1 (ppm) 1674.7714527097244 1058.5685215346136 1145.3534029887041 869.0033604795168 2538.792480773764 1658.8827772689967 2059.553091725453 2570.9977668595743 2883.9895933756457 3502.5506141463834 3817.4057084277374 4147.603113123243 3786.6839268140516 3025.132370970289 +TPS1 (ppm) 1514.1334067391 1515.348362968769 2060.6929085587426 2163.3874853265006 979.1287261483814 1097.3196496052797 1164.9836222266688 1227.7789514529609 1033.6706397154219 801.9883294899911 569.1124579303535 501.8646404943031 522.4685915354274 443.82896376249425 +GSY2 (ppm) 174.866488316802 165.3605410879714 173.7351646895035 169.19041810789497 58.40054053434133 216.640895622035 213.23124842856961 155.63199316086215 121.22756807991051 81.4785529211565 47.19913529944502 37.40346967862057 35.11736376666467 49.84757681453397 diff --git a/literature/xia2022/comparison/tables/tables.md b/literature/xia2022/comparison/tables/tables.md new file mode 100644 index 0000000..b022d31 --- /dev/null +++ b/literature/xia2022/comparison/tables/tables.md @@ -0,0 +1,128 @@ +## Table 1. Conditions, measured and modelled exchange rates (mmol/gDW/h), and the caps the pipeline changed + +| dataset | condition | D | Ptot | Glucose meas | Glucose model | CO2 meas | CO2 model | Oxygen meas | Oxygen model | Ethanol meas | Ethanol model | caps raised to minimum | caps relaxed for growth | caps relaxed for rates | mg/gDW added for rates | +|:----------------|:------------|------:|-------:|---------------:|----------------:|-----------:|------------:|--------------:|---------------:|---------------:|----------------:|-------------------------:|--------------------------:|-------------------------:|-------------------------:| +| This study | CN4 | 0.1 | 0.5 | 1.12 | 1.2 | 3.09 | 3.1 | 2.93 | 2.73 | 0 | 0 | 9 | 12 | 0 | 0 | +| This study | CN22 | 0.1 | 0.55 | 1.48 | 1.6 | 4.07 | 4.4 | 4.19 | 3.85 | 0 | 0 | 11 | 5 | 3 | 0.299 | +| This study | CN38 | 0.1 | 0.33 | 2.01 | 2.17 | 6.3 | 5.8 | 5.17 | 4.95 | 0.79 | 0.747 | 18 | 8 | 15 | 5.42 | +| This study | CN75 | 0.1 | 0.27 | 3.23 | 3.49 | 7.88 | 8.51 | 6.66 | 6.13 | 2.28 | 2.1 | 18 | 9 | 19 | 8.01 | +| This study | hGR | 0.29 | 0.41 | 5.42 | 5.85 | 11 | 11.9 | 7.66 | 7.57 | 3.68 | 3.39 | 24 | 16 | 8 | 1.19 | +| Xia et al. 2022 | μ0.03 | 0.027 | 0.299 | 0.326 | 0.378 | 0.957 | 0.972 | 0.841 | 0.827 | 0 | 0 | 7 | 0 | 0 | 0 | +| Xia et al. 2022 | μ0.04 | 0.044 | 0.312 | 0.494 | 0.573 | 1.56 | 1.62 | 1.54 | 1.46 | 0 | 0 | 8 | 0 | 0 | 0 | +| Xia et al. 2022 | μ0.10 | 0.102 | 0.371 | 1.14 | 1.33 | 2.69 | 3.12 | 2.42 | 2.81 | 0 | 0 | 11 | 3 | 5 | 0.752 | +| Xia et al. 2022 | μ0.15 | 0.152 | 0.419 | 1.6 | 1.86 | 3.88 | 4.5 | 4.06 | 4.08 | 0 | 0 | 14 | 11 | 7 | 0.966 | +| Xia et al. 2022 | μ0.21 | 0.214 | 0.32 | 2.37 | 2.75 | 5.92 | 6.87 | 5.63 | 6.37 | 0 | 0 | 16 | 13 | 5 | 0.86 | +| Xia et al. 2022 | μ0.25 | 0.254 | 0.378 | 2.71 | 3.15 | 6.81 | 7.9 | 5.91 | 6.85 | 0 | 0.01 | 19 | 14 | 7 | 0.502 | +| Xia et al. 2022 | μ0.28 | 0.284 | 0.391 | 3.14 | 3.65 | 8.54 | 9.8 | 7.98 | 8.67 | 0 | 0 | 26 | 15 | 0 | 0 | +| Xia et al. 2022 | μ0.33 | 0.334 | 0.419 | 4.88 | 5.66 | 12.2 | 13.1 | 9.64 | 9.11 | 2.19 | 1.84 | 29 | 15 | 7 | 0.22 | +| Xia et al. 2022 | μ0.38 | 0.378 | 0.391 | 6.71 | 7.78 | 14.4 | 16.7 | 9.59 | 9.61 | 5.83 | 4.9 | 28 | 17 | 9 | 1.2 | + +## Table 2. Capacity usage per system: enzyme mass used over the measured capacity of its enzymes (%) + +| system | CN4 | CN22 | CN38 | CN75 | hGR | μ0.03 | μ0.04 | μ0.10 | μ0.15 | μ0.21 | μ0.25 | μ0.28 | μ0.33 | μ0.38 | +|:----------------------|------:|-------:|-------:|-------:|-------:|--------:|--------:|--------:|--------:|--------:|--------:|--------:|--------:|--------:| +| Glycolysis | 2.34 | 2.74 | 6.13 | 9.37 | 13.8 | 1.18 | 1.8 | 4.31 | 6.43 | 20.1 | 27.8 | 29 | 41.7 | 51.5 | +| TCA cycle | 9.2 | 18.6 | 33.3 | 50.5 | 25.8 | 3.96 | 6.85 | 10.2 | 11.6 | 21.7 | 17.9 | 19.6 | 21.6 | 26.2 | +| ETC | 19.7 | 30.5 | 45.2 | 86.4 | 68.2 | 13.4 | 22.9 | 34 | 37.3 | 71.4 | 61.1 | 67.3 | 67 | 83.2 | +| Ribosome | 26.8 | 29.5 | 46.1 | 52.8 | 70.3 | 14.6 | 21.5 | 35.5 | 41 | 65.2 | 63.1 | 64.7 | 64.9 | 70.8 | +| PP shunt | 11 | 1.65 | 1.32 | 1.44 | 4.33 | 3.01 | 2.98 | 5.89 | 17.1 | 9.88 | 12.3 | 8.71 | 7.2 | 10 | +| THF cycle | 19.2 | 87 | 68.5 | 97.8 | 55.6 | 5.95 | 9.17 | 14.7 | 17.1 | 25.8 | 31.1 | 36.5 | 35.6 | 39.1 | +| Nitrogen metabolism | 0 | 2.49 | nan | nan | nan | 0 | 0 | nan | 0 | nan | nan | nan | nan | nan | +| Amino acid metabolism | 10.4 | 12.3 | 21.4 | 30.7 | 24.6 | 5.61 | 7.52 | 12.1 | 14.2 | 23.7 | 23.9 | 24 | 26.6 | 29.1 | + +## Table 3. Enzyme mass used and measured capacity per system (mg/gDW) + +| system | mg/gDW | CN4 | CN22 | CN38 | CN75 | hGR | μ0.03 | μ0.04 | μ0.10 | μ0.15 | μ0.21 | μ0.25 | μ0.28 | μ0.33 | μ0.38 | +|:-----------|:------------------|-------:|-------:|-------:|-------:|------:|--------:|--------:|--------:|--------:|--------:|--------:|--------:|--------:|--------:| +| Glycolysis | used | 1.59 | 2.02 | 2.85 | 3.71 | 5.21 | 0.506 | 0.777 | 1.69 | 2.53 | 5.12 | 7.47 | 8.4 | 14.4 | 20.2 | +| Glycolysis | measured capacity | 68.1 | 73.7 | 46.4 | 39.6 | 37.8 | 42.9 | 43 | 39.2 | 39.4 | 25.4 | 26.9 | 29 | 34.5 | 39.3 | +| TCA cycle | used | 0.865 | 1.34 | 1.56 | 1.66 | 2.16 | 0.258 | 0.484 | 0.903 | 1.28 | 2.12 | 2.2 | 2.91 | 2.83 | 2.89 | +| TCA cycle | measured capacity | 9.4 | 7.17 | 4.68 | 3.29 | 8.38 | 6.52 | 7.07 | 8.9 | 11 | 9.77 | 12.3 | 14.8 | 13.1 | 11 | +| ETC | used | 0.455 | 0.645 | 0.827 | 1.03 | 1.26 | 0.444 | 0.785 | 1.51 | 2.19 | 3.4 | 3.67 | 4.64 | 4.85 | 5.14 | +| ETC | measured capacity | 2.32 | 2.11 | 1.83 | 1.19 | 1.85 | 3.32 | 3.43 | 4.42 | 5.86 | 4.77 | 6.01 | 6.9 | 7.24 | 6.18 | +| Ribosome | used | 11.6 | 11.6 | 11.6 | 11.6 | 33.6 | 3.09 | 5.04 | 11.7 | 17.4 | 24.5 | 29.1 | 32.6 | 38.2 | 43.4 | +| Ribosome | measured capacity | 43.3 | 39.3 | 25.1 | 22 | 47.8 | 21.2 | 23.5 | 33 | 42.5 | 37.7 | 46.1 | 50.3 | 58.9 | 61.3 | + +## Table 4. Sampled ATP and redox budget (mean over samples, mmol/gDW/h) + +| flux (mmol/gDW/h) | CN4 | CN22 | CN38 | CN75 | hGR | μ0.03 | μ0.04 | μ0.10 | μ0.15 | μ0.21 | μ0.25 | μ0.28 | μ0.33 | μ0.38 | +|:--------------------------------|-------:|-------:|-------:|-------:|------:|--------:|--------:|--------:|--------:|--------:|--------:|--------:|--------:|--------:| +| glucose uptake | 1.17 | 1.54 | 2.11 | 3.37 | 5.66 | 0.373 | 0.57 | 1.31 | 1.86 | 2.71 | 3.13 | 3.59 | 5.57 | 7.67 | +| ATP from ETC | 8.18 | 12.2 | 14.6 | 19 | 22 | 2.79 | 5.02 | 7.84 | 13.2 | 18.1 | 19.5 | 25.9 | 31.5 | 30.3 | +| ATP from glycolysis | 1.22 | 1.94 | 2.3 | 4.53 | 7.64 | 0.422 | 0.594 | 1.45 | 2.03 | 2.78 | 3.47 | 3.96 | 7.42 | 10.9 | +| ETC share of ATP supply (%) | 87 | 86.3 | 86.3 | 80.7 | 74.2 | 86.9 | 89.4 | 84.4 | 86.7 | 86.7 | 84.9 | 86.7 | 81 | 73.5 | +| ATP per glucose via ETC | 6.99 | 7.9 | 6.88 | 5.63 | 3.89 | 7.48 | 8.82 | 5.99 | 7.09 | 6.68 | 6.24 | 7.21 | 5.67 | 3.94 | +| ATP for growth (GAEC) | 5.53 | 5.66 | 5.14 | 5 | 15.4 | 1.21 | 1.98 | 4.73 | 7.18 | 9.69 | 11.8 | 13.3 | 15.8 | 17.7 | +| ATP not tied to growth (NGAM) | 0.819 | 4.49 | 8.57 | 14.7 | 4.82 | 1.4 | 2.55 | 2.16 | 3.19 | 6.36 | 5.2 | 9.56 | 14.5 | 13.9 | +| ATP for other metabolism | 3.06 | 3.98 | 3.15 | 3.82 | 9.37 | 0.6 | 1.08 | 2.41 | 4.82 | 4.81 | 5.98 | 7.03 | 8.65 | 9.59 | +| pyruvate dehydrogenase | 1.05 | 1.58 | 1.77 | 2.6 | 3.73 | 0.337 | 0.623 | 1.03 | 1.67 | 2.48 | 2.42 | 3.44 | 3.96 | 4.34 | +| isocitrate dehydrogenase (mito) | 0.795 | 1.11 | 1.4 | 1.56 | 1.07 | 0.294 | 0.603 | 0.641 | 1.4 | 1.65 | 1.77 | 2.33 | 3.12 | 2.12 | +| external NADH dehydrogenase | 1.8 | 2.59 | 3.05 | 4.34 | 5.89 | 0.513 | 0.848 | 1.8 | 2.76 | 3.72 | 4.29 | 5.13 | 6.49 | 12.8 | +| NADPH turnover (total) | 1.64 | 1.87 | 1.68 | 2.01 | 5.18 | 0.326 | 0.661 | 1.41 | 2.36 | 3.35 | 3.11 | 4.24 | 5.18 | 6.38 | + +## Table 5. Respiratory limit: the highest glucose uptake the measured proteome can respire completely at the condition's growth rate (mmol/gDW/h) + +| dataset | variant | condition | D | glucose_measured | ethanol_measured | caps_lifted | caps_restored | uptake_min | uptake_max | respiratory_limit | limiting | +|:----------------|:----------|:------------|------:|-------------------:|-------------------:|--------------:|----------------:|-------------:|-------------:|--------------------:|:-----------------------------------------------------------------------| +| This study | lifted | CN4 | 0.1 | 1.12 | 0 | 20 | 0 | 1.18 | 17.7 | 1.95 | SDH3 (TCA cycle); RPE1 (PP shunt); YJR073C (other) | +| This study | lifted | CN22 | 0.1 | 1.48 | 0 | 17 | 0 | 1.37 | 16.8 | 1.57 | SDH3 (TCA cycle); RKI1 (PP shunt); YPR021C (other) | +| This study | lifted | CN38 | 0.1 | 2.01 | 0.79 | 34 | 0 | 1.24 | 12.3 | 2.13 | IDP2 (TCA cycle); KGD2 (TCA cycle); SOL3 (PP shunt) | +| This study | lifted | CN75 | 0.1 | 3.23 | 2.28 | 38 | 0 | 1.25 | 10.9 | 2.19 | COX9 (ETC); YGL001C (other); SOL3 (PP shunt) | +| This study | lifted | hGR | 0.29 | 5.42 | 3.68 | 36 | 0 | 3.46 | 16 | 3.94 | COX3 (ETC); GLY1 (Amino acid metabolism); YIL160C (other) | +| Xia et al. 2022 | lifted | mu003 | 0.027 | 0.326 | 0 | 7 | 0 | 0.318 | 7.42 | 1.14 | YJR048W (other); YEL039C (other); YBR041W (other) | +| Xia et al. 2022 | lifted | mu004 | 0.044 | 0.494 | 0 | 8 | 0 | 0.519 | 8.31 | 1.44 | YJR048W (other); YEL039C (other); YBR041W (other) | +| Xia et al. 2022 | lifted | mu010 | 0.102 | 1.14 | 0 | 17 | 0 | 1.23 | 6.93 | 2.09 | YBR041W (other); COX1 (ETC); GLY1 (Amino acid metabolism) | +| Xia et al. 2022 | lifted | mu015 | 0.152 | 1.6 | 0 | 22 | 0 | 1.79 | 6.97 | 3.23 | COB (ETC); GLY1 (Amino acid metabolism); YHR190W (other) | +| Xia et al. 2022 | lifted | mu021 | 0.214 | 2.37 | 0 | 25 | 0 | 2.56 | 4.36 | 3.3 | COX2 (ETC); YBR041W (other); YLR231C (other) | +| Xia et al. 2022 | lifted | mu025 | 0.254 | 2.71 | 0 | 30 | 0 | 2.99 | 3.91 | 3.88 | RPE1 (PP shunt); TDH1 (Glycolysis); TYR1 (Amino acid metabolism) | +| Xia et al. 2022 | lifted | mu028 | 0.284 | 3.14 | 0 | 36 | 0 | 3.4 | 4.36 | 4.32 | RPE1 (PP shunt); TDH1 (Glycolysis); TYR1 (Amino acid metabolism) | +| Xia et al. 2022 | lifted | mu033 | 0.334 | 4.88 | 2.19 | 41 | 0 | 3.97 | 15.7 | 5.06 | COX1 (ETC); GLY1 (Amino acid metabolism); YIL160C (other) | +| Xia et al. 2022 | lifted | mu038 | 0.378 | 6.71 | 5.83 | 41 | 0 | 4.51 | 15.6 | 5.06 | COX2 (ETC); GLY1 (Amino acid metabolism); TRP4 (Amino acid metabolism) | +| This study | measured | CN4 | 0.1 | 1.12 | 0 | 20 | 0 | 1.18 | 17.7 | 1.95 | SDH3 (TCA cycle); RPE1 (PP shunt); YJR073C (other) | +| This study | measured | CN22 | 0.1 | 1.48 | 0 | 16 | 1 | 1.37 | 16.8 | 1.56 | SDH3 (TCA cycle); RKI1 (PP shunt); YPR021C (other) | +| This study | measured | CN38 | 0.1 | 2.01 | 0.79 | 22 | 12 | 1.53 | 12.3 | nan | none (window end) | +| This study | measured | CN75 | 0.1 | 3.23 | 2.28 | 22 | 16 | 1.75 | 10.9 | nan | none (window end) | +| This study | measured | hGR | 0.29 | 5.42 | 3.68 | 35 | 1 | 3.83 | 16 | nan | none (window end) | +| Xia et al. 2022 | measured | mu003 | 0.027 | 0.326 | 0 | 7 | 0 | 0.318 | 7.42 | 1.14 | YJR048W (other); YEL039C (other); YBR041W (other) | +| Xia et al. 2022 | measured | mu004 | 0.044 | 0.494 | 0 | 8 | 0 | 0.519 | 8.31 | 1.44 | YJR048W (other); YEL039C (other); YBR041W (other) | +| Xia et al. 2022 | measured | mu010 | 0.102 | 1.14 | 0 | 13 | 4 | 1.24 | 6.93 | 2.09 | COX3 (ETC); YBR041W (other); GLY1 (Amino acid metabolism) | +| Xia et al. 2022 | measured | mu015 | 0.152 | 1.6 | 0 | 22 | 0 | 1.79 | 6.97 | 3.23 | COB (ETC); GLY1 (Amino acid metabolism); YHR190W (other) | +| Xia et al. 2022 | measured | mu021 | 0.214 | 2.37 | 0 | 25 | 0 | 2.56 | 4.36 | 3.3 | COX2 (ETC); YBR041W (other); YLR231C (other) | +| Xia et al. 2022 | measured | mu025 | 0.254 | 2.71 | 0 | 29 | 1 | 2.99 | 3.91 | 3.88 | RPE1 (PP shunt); TDH1 (Glycolysis); TYR1 (Amino acid metabolism) | +| Xia et al. 2022 | measured | mu028 | 0.284 | 3.14 | 0 | 36 | 0 | 3.4 | 4.36 | 4.32 | RPE1 (PP shunt); TDH1 (Glycolysis); TYR1 (Amino acid metabolism) | +| Xia et al. 2022 | measured | mu033 | 0.334 | 4.88 | 2.19 | 40 | 1 | 4.36 | 14.9 | nan | none (window end) | +| Xia et al. 2022 | measured | mu038 | 0.378 | 6.71 | 5.83 | 40 | 1 | 4.51 | 15.6 | 5.06 | COX2 (ETC); GLY1 (Amino acid metabolism); TRP4 (Amino acid metabolism) | + +## Table 6. Respiratory-chain kcats derived from each dataset: the highest apparent turnover across its conditions + +| dataset | complex | reaction | set by | derived kcat (1/s) | ecModel kcat (1/s) | +|:----------------|:-------------|:-----------|:---------|---------------------:|---------------------:| +| This study | ATP synthase | r_0226 | CN75 | 1.61e+03 | 84.6 | +| This study | complex III | r_0439 | CN75 | 1.45e+03 | 290 | +| This study | complex IV | r_0438 | CN75 | 3.24e+03 | 1.38e+03 | +| Xia et al. 2022 | ATP synthase | r_0226 | μ0.38 | 447 | 84.6 | +| Xia et al. 2022 | complex III | r_0439 | μ0.38 | 427 | 290 | +| Xia et al. 2022 | complex IV | r_0438 | μ0.38 | 1.09e+03 | 1.38e+03 | + +## Table 7. Physiology from the measured rates and marker proteins (ppm of the measured protein mass; empty: not detected) + +| quantity | CN4 | CN22 | CN38 | CN75 | hGR | μ0.03 | μ0.04 | μ0.10 | μ0.15 | μ0.21 | μ0.25 | μ0.28 | μ0.33 | μ0.38 | +|:-----------------------------|-----------:|-----------:|-----------:|-----------:|-----------:|-----------:|-----------:|-----------:|-----------:|-----------:|-----------:|-----------:|-----------:|-----------:| +| biomass yield (g/g glucose) | 0.498 | 0.376 | 0.276 | 0.172 | 0.297 | 0.46 | 0.494 | 0.496 | 0.526 | 0.501 | 0.52 | 0.502 | 0.38 | 0.313 | +| glucose per biomass (mmol/g) | 11.2 | 14.8 | 20.1 | 32.3 | 18.7 | 12.1 | 11.2 | 11.2 | 10.5 | 11.1 | 10.7 | 11.1 | 14.6 | 17.7 | +| O2 per glucose | 2.63 | 2.83 | 2.57 | 2.06 | 1.41 | 2.58 | 3.12 | 2.12 | 2.53 | 2.37 | 2.18 | 2.54 | 1.98 | 1.43 | +| RQ | 1.05 | 0.972 | 1.22 | 1.18 | 1.44 | 1.14 | 1.01 | 1.11 | 0.956 | 1.05 | 1.15 | 1.07 | 1.27 | 1.5 | +| formate (mmol/gDW/h) | 0 | 0.0486 | 0.344 | 0.48 | 0 | nan | nan | nan | nan | nan | nan | nan | nan | nan | +| carbon recovery | 1.07 | 0.923 | 1.08 | 0.942 | 0.97 | 1.05 | 1.13 | 0.997 | 1.05 | 1.03 | 1.05 | 1.07 | 1.03 | 1.03 | +| GAP1 (ppm) | nan | 1.9e+03 | 1.62e+03 | 1.42e+03 | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | +| GLN1 (ppm) | 359 | 2.8e+03 | 2.52e+03 | 2.46e+03 | 940 | 303 | 403 | 647 | 815 | 1e+03 | 1.06e+03 | 1.14e+03 | 1.28e+03 | 1.28e+03 | +| GDH1 (ppm) | 2.9e+03 | 9.72e+03 | 9.76e+03 | 9e+03 | 6e+03 | 1.28e+03 | 2.1e+03 | 4.49e+03 | 5.69e+03 | 7.09e+03 | 7.12e+03 | 6.46e+03 | 6.26e+03 | 6.47e+03 | +| GCV1 (ppm) | 293 | 705 | 537 | 543 | 275 | 375 | 382 | 464 | 485 | 458 | 449 | 426 | 448 | 464 | +| GCV2 (ppm) | 200 | 535 | 430 | 439 | 308 | 259 | 388 | 626 | 681 | 676 | 652 | 579 | 565 | 604 | +| SHM2 (ppm) | 3.18e+03 | 3.12e+03 | 3.33e+03 | 3.85e+03 | 5.45e+03 | 2.56e+03 | 2.95e+03 | 3.6e+03 | 3.98e+03 | 4.32e+03 | 4.56e+03 | 4.96e+03 | 5.9e+03 | 6.58e+03 | +| MTD1 (ppm) | 204 | 226 | 237 | 252 | 244 | 237 | 265 | 297 | 317 | 313 | 305 | 289 | 328 | 359 | +| FDH1 (ppm) | nan | nan | nan | nan | nan | 1.55e+03 | 1.71e+03 | 755 | 505 | 353 | 221 | 83.1 | 164 | 108 | +| CIT1 (ppm) | 3.68e+03 | 2.42e+03 | 2.14e+03 | 1.63e+03 | 5.43e+03 | 2.85e+03 | 2.84e+03 | 2.96e+03 | 3.28e+03 | 4.01e+03 | 4.96e+03 | 6.09e+03 | 5.04e+03 | 3.76e+03 | +| SDH1 (ppm) | 1.67e+03 | 1.06e+03 | 1.15e+03 | 869 | 2.54e+03 | 1.66e+03 | 2.06e+03 | 2.57e+03 | 2.88e+03 | 3.5e+03 | 3.82e+03 | 4.15e+03 | 3.79e+03 | 3.03e+03 | +| TPS1 (ppm) | 1.51e+03 | 1.52e+03 | 2.06e+03 | 2.16e+03 | 979 | 1.1e+03 | 1.16e+03 | 1.23e+03 | 1.03e+03 | 802 | 569 | 502 | 522 | 444 | +| GSY2 (ppm) | 175 | 165 | 174 | 169 | 58.4 | 217 | 213 | 156 | 121 | 81.5 | 47.2 | 37.4 | 35.1 | 49.8 | diff --git a/literature/xia2022/data/README.md b/literature/xia2022/data/README.md new file mode 100644 index 0000000..c04ddde --- /dev/null +++ b/literature/xia2022/data/README.md @@ -0,0 +1,37 @@ +# Data: glucose-limited chemostat series + +Nine conditions from the chemostat series of Xia et al. (2022), *Nat Commun* 13:2819, [doi:10.1038/s41467-022-30513-2](https://doi.org/10.1038/s41467-022-30513-2), in the formats of the pipeline's `data/`. + +| Condition | D [1/h] | Proteomics samples | Ptot [g/gDW] | +|---|---|---|---| +| mu003 | 0.027 | S1–S3 (μ = 0.027) | 0.299 | +| mu004 | 0.044 | S4–S6 (μ = 0.044) | 0.312 | +| mu010 | 0.10225 | S7–S9 (μ = 0.102) | 0.371 | +| mu015 | 0.152 | S10–S12 (μ = 0.152) | 0.419 | +| mu021 | 0.21425 | S13–S15 (μ = 0.214) | 0.320 | +| mu025 | 0.254 | S16–S18 (μ = 0.254) | 0.378 | +| mu028 | 0.28425 | S19–S21 (μ = 0.284) | 0.391 | +| mu033 | 0.33375 | S22–S24 (μ = 0.334) | 0.419 | +| mu038 | 0.3785 | S25–S27 (μ = 0.379) | 0.391 | + +The source spreadsheets of the paper are not committed: + +- the extracellular fluxes (sheet `Fig.1B`): D, glucose, CO2, O2 and ethanol rates. Glycerol, acetate and formate are not in it and are `NA`, which the pipeline reads as undetected; ethanol is `NA` where it is 0. With `--fit-rates`, and in sampling, an undetected byproduct may still be secreted at up to 0.01 mmol/gDW/h, as in this study. +- the proteomics, in copies per cell. +- Ptot, the total protein content, is from Supplementary Table 6 of the paper (Supplementary Information, p. 28). Its standard deviation is up to 4.8 percentage points (mu021) and 6.5 (mu038); mu021's 0.320 breaks an otherwise rising series. + +`../scripts/prepare_data.py` writes the first two files from the spreadsheets; Ptot is written into its condition table. + +- `fermentationData.txt`: the rates and Ptot per condition. +- `abs_proteomics.txt`: copies per cell converted per sample to mmol/gDW by scaling the sample's total protein mass to its condition's Ptot, with the molecular masses in `data/uniprot.tsv` of the repository. Protein groups (`A:B`, mostly ribosomal paralogs) are assigned to their first member with a known mass, isoform suffixes stripped. +- `ribosome_core.tsv`: the core ribosome used (see below). + +Scaling to Ptot follows the paper, which derived copies per cell from each protein's share of the total protein content. Each sample's measured protein mass therefore equals Ptot, whereas the measured mass in this study is 72–83% of Ptot. Converting with the paper's 13 pg/cell dry weight instead would give 0.70–1.22× Ptot, from 1.20–1.22× at mu003 to 0.88–0.92× at mu033; the replicates of mu021 (0.80–1.13×) and mu038 (0.70–1.04×) spread the most. + +Unlike the data of this study, this series quantifies ribosomal paralog groups (4–7.5% of the measured mass, rising with growth rate). They are not model enzymes, so they lower f. + +## Core ribosome + +The 48 subunits of this study, except at seven positions where the measured paralog takes the place of this study's member (`this_study_uniprot` gives the one it replaces). At five of them this series has the other paralog 5–295× more abundant, where this study had its own member more abundant: RPL26 (295×), RPL9 (22×), RPS1 (8.6×), RPL21 (8.1×) and RPL8 (5.2×). At the other two this study's member lacks a measurement in some samples, so the pipeline gives it no average: RPS19B is missing in 8 of 27 samples (RPS19A is 5.3× more abundant), and RPL33B is in one sample of 27, where it is 7× more abundant than RPL33A. RPL33A averages 6.6e-6 mmol/gDW, below the core threshold of 1e-5, and is the only swapped subunit the model raises (1.08–4.6×, at every condition but mu003). RPS10B is not in this series; neither RPS10 paralog was detected. + +Re-selected by abundance on this series the core has 77 subunits, among them paralog groups, both paralogs of RPL6 and RPL16, and TEF4, so the two datasets would no longer model the same ribosome. diff --git a/literature/xia2022/data/abs_proteomics.txt b/literature/xia2022/data/abs_proteomics.txt new file mode 100644 index 0000000..71517de --- /dev/null +++ b/literature/xia2022/data/abs_proteomics.txt @@ -0,0 +1,2822 @@ +Protein.IDs Gene mu003_1_abs mu003_2_abs mu003_3_abs mu004_1_abs mu004_2_abs mu004_3_abs mu010_1_abs mu010_2_abs mu010_3_abs mu015_1_abs mu015_2_abs mu015_3_abs mu021_1_abs mu021_2_abs mu021_3_abs mu025_1_abs mu025_2_abs mu025_3_abs mu028_1_abs mu028_2_abs mu028_3_abs mu033_1_abs mu033_2_abs mu033_3_abs mu038_1_abs mu038_2_abs mu038_3_abs +P19097 YPL231W 8.811884E-06 8.524844E-06 8.874665E-06 1.254674E-05 1.279387E-05 1.254004E-05 1.622710E-05 1.656939E-05 1.625451E-05 1.662841E-05 1.812697E-05 1.848234E-05 1.223066E-05 1.168652E-05 1.250159E-05 1.134062E-05 1.198950E-05 1.179787E-05 1.153546E-05 1.202748E-05 1.184368E-05 1.094630E-05 1.137549E-05 1.050200E-05 9.168070E-06 1.039037E-05 9.155874E-06 +Q00955 YNR016C 8.654543E-06 8.460946E-06 8.799646E-06 9.107797E-06 8.677971E-06 9.133279E-06 7.890096E-06 8.152210E-06 8.168456E-06 7.399056E-06 8.111102E-06 7.894963E-06 5.435806E-06 5.344868E-06 5.867837E-06 5.952608E-06 6.262254E-06 6.204456E-06 6.902897E-06 7.343778E-06 7.121995E-06 7.047916E-06 7.163322E-06 6.798176E-06 6.008155E-06 6.643354E-06 5.938739E-06 +P07259 YJL130C 4.205949E-06 4.155552E-06 4.244178E-06 4.514953E-06 4.549555E-06 4.489893E-06 5.941489E-06 6.027181E-06 5.935987E-06 6.263817E-06 6.807758E-06 6.870772E-06 4.917056E-06 4.906188E-06 5.334495E-06 5.505420E-06 5.567334E-06 5.793191E-06 5.770129E-06 6.750295E-06 5.886549E-06 7.376307E-06 7.478462E-06 7.349241E-06 6.578154E-06 7.656738E-06 7.264803E-06 +P07149 YKL182W 7.587105E-06 7.274130E-06 7.539525E-06 1.051100E-05 1.072588E-05 1.052443E-05 1.355615E-05 1.393970E-05 1.369616E-05 1.375847E-05 1.522884E-05 1.539165E-05 1.009664E-05 9.565705E-06 1.035773E-05 9.513055E-06 9.812070E-06 9.713586E-06 9.565665E-06 9.796232E-06 9.701143E-06 9.129864E-06 9.446535E-06 8.484387E-06 7.548972E-06 8.608943E-06 7.323922E-06 +P06105 YJL080C 1.695700E-06 1.665768E-06 1.678264E-06 1.855995E-06 1.836747E-06 1.805882E-06 2.599408E-06 2.661758E-06 2.595928E-06 3.119426E-06 3.232025E-06 3.270571E-06 2.535429E-06 2.523271E-06 2.663821E-06 3.196148E-06 3.220116E-06 3.326860E-06 3.493627E-06 3.625454E-06 3.402493E-06 4.247295E-06 4.280745E-06 4.418352E-06 4.135166E-06 4.312928E-06 4.356877E-06 +P47169 YJR137C 2.239209E-06 2.199954E-06 2.256832E-06 3.088498E-06 3.273389E-06 3.191124E-06 5.043211E-06 5.167189E-06 5.000427E-06 5.744546E-06 6.324699E-06 6.360877E-06 4.905424E-06 4.985187E-06 5.250564E-06 6.173155E-06 6.229937E-06 6.581840E-06 6.950683E-06 7.241370E-06 6.951519E-06 8.070727E-06 8.027019E-06 7.942129E-06 7.293770E-06 8.175272E-06 8.293315E-06 +Q05022 YMR229C 4.658665E-07 4.701047E-07 5.070392E-07 5.490592E-07 5.465821E-07 5.355030E-07 8.059444E-07 8.251588E-07 8.277751E-07 9.635011E-07 1.092848E-06 1.055295E-06 8.278847E-07 8.383902E-07 9.462921E-07 1.083673E-06 1.086857E-06 1.157593E-06 1.129688E-06 1.175102E-06 1.163898E-06 1.358472E-06 1.351668E-06 1.358277E-06 1.266563E-06 1.453228E-06 1.486559E-06 +Q12680 YDL171C 9.374971E-07 9.297021E-07 9.559635E-07 1.121570E-06 1.186707E-06 1.149102E-06 1.972397E-06 1.914585E-06 1.846452E-06 2.175594E-06 2.340994E-06 2.499250E-06 1.888507E-06 1.837319E-06 1.925199E-06 1.979296E-06 2.042548E-06 2.051392E-06 2.104724E-06 2.120486E-06 2.134737E-06 2.078317E-06 2.090778E-06 1.991731E-06 1.775537E-06 1.957157E-06 1.827752E-06 +P38249 YBR079C 1.914165E-06 1.873202E-06 1.899185E-06 2.078951E-06 2.168283E-06 2.065604E-06 2.993438E-06 3.036314E-06 2.949219E-06 3.657314E-06 3.828765E-06 3.853271E-06 3.109390E-06 3.205162E-06 3.274414E-06 3.979822E-06 4.039599E-06 4.003428E-06 4.289476E-06 4.313667E-06 4.234939E-06 4.716568E-06 4.709282E-06 4.661018E-06 4.427982E-06 4.549593E-06 4.565607E-06 +P22147 YGL173C 4.601117E-07 4.160721E-07 4.468122E-07 4.868524E-07 4.680052E-07 4.650242E-07 6.833976E-07 7.209351E-07 6.354316E-07 7.215643E-07 7.246578E-07 7.692635E-07 6.073329E-07 5.792992E-07 6.600292E-07 6.367887E-07 6.811900E-07 7.342725E-07 7.421334E-07 7.272313E-07 6.932244E-07 7.766425E-07 7.855606E-07 7.731730E-07 7.416955E-07 7.846119E-07 7.178276E-07 +P10964 YOR341W 5.695833E-07 5.476535E-07 5.621138E-07 6.431233E-07 6.654697E-07 6.509397E-07 9.340756E-07 9.517632E-07 8.825270E-07 1.038989E-06 1.129612E-06 1.151139E-06 9.032919E-07 9.167833E-07 9.557725E-07 1.092262E-06 1.127907E-06 1.121544E-06 1.191507E-06 1.257221E-06 1.189641E-06 1.299337E-06 1.356642E-06 1.308612E-06 1.254912E-06 1.448578E-06 1.438881E-06 +Q03690 YMR012W 1.444727E-06 1.460646E-06 1.444017E-06 1.604577E-06 1.576869E-06 1.574397E-06 2.727006E-06 2.795425E-06 2.499212E-06 3.280007E-06 3.740318E-06 3.646781E-06 3.026438E-06 3.172899E-06 3.288138E-06 4.125108E-06 4.274247E-06 4.408345E-06 5.505274E-06 5.881435E-06 5.368626E-06 5.744901E-06 5.842845E-06 5.546282E-06 5.115538E-06 5.441323E-06 5.183525E-06 +P05694 YER091C 1.504578E-05 1.444733E-05 1.478868E-05 2.105019E-05 2.202918E-05 2.184018E-05 3.995297E-05 3.951555E-05 3.804541E-05 5.103594E-05 5.287676E-05 5.230614E-05 4.296570E-05 4.474046E-05 4.561626E-05 6.216054E-05 6.110276E-05 6.380073E-05 7.445884E-05 7.869188E-05 7.376499E-05 8.961862E-05 8.724508E-05 8.800260E-05 8.129388E-05 8.524317E-05 8.561071E-05 +P31539 YLL026W 4.044622E-05 4.014961E-05 3.843642E-05 3.449308E-05 3.270521E-05 3.335619E-05 2.284939E-05 2.290675E-05 2.494801E-05 1.924601E-05 1.782025E-05 1.783501E-05 8.739897E-06 6.677623E-06 7.007627E-06 5.074218E-06 5.056988E-06 4.681999E-06 4.594772E-06 5.138248E-06 4.557345E-06 5.632685E-06 5.596889E-06 5.492288E-06 5.003689E-06 4.834276E-06 4.650737E-06 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1.680772E-07 1.633042E-07 NA 1.421751E-07 1.474881E-07 +P53951 YNL051W NA NA 2.672548E-08 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P53952 YNL050C NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 7.473637E-08 NA NA NA NA 7.723534E-08 NA NA NA NA +P54837 YML012W 1.050091E-07 1.364558E-07 1.235715E-07 1.270266E-07 NA 1.395477E-07 NA 2.076589E-07 1.862560E-07 2.651204E-07 2.327985E-07 2.302957E-07 1.990846E-07 NA 1.635209E-07 1.998261E-07 1.910358E-07 NA 1.669458E-07 NA 1.964453E-07 1.825503E-07 NA NA NA NA 1.690169E-07 +P54999 YPR182W 4.413733E-07 2.697381E-07 NA NA 3.391351E-07 NA 1.389358E-07 3.422216E-07 NA NA 4.587287E-07 NA 1.551152E-06 1.223129E-07 4.371242E-07 1.577322E-07 4.493593E-07 8.834959E-07 5.898040E-07 1.305269E-07 2.170585E-07 2.775158E-06 5.819236E-07 9.105838E-07 5.542221E-07 2.338265E-06 NA +P57743 YLR438C-A 1.247170E-06 NA 1.186408E-06 1.120965E-06 NA NA 1.476734E-06 NA NA NA NA NA 1.285264E-06 NA NA 1.476033E-06 NA 1.632198E-06 NA NA 1.675848E-06 NA NA NA NA NA 1.424522E-06 +P80967 YPR133W-A NA NA 1.377162E-06 NA 1.939637E-06 NA NA NA NA NA NA NA 2.863659E-06 NA 2.898374E-06 3.563048E-06 NA 3.564285E-06 4.254043E-06 NA NA NA 4.455776E-06 3.856709E-06 3.778120E-06 4.007672E-06 NA +Q02260 YGR074W 4.587944E-07 NA NA NA NA NA NA NA NA NA NA NA NA NA NA 4.753476E-07 NA NA NA NA 5.794918E-07 5.891065E-07 6.148678E-07 NA NA 5.705853E-07 NA +Q02771 YER058W 7.600439E-07 7.262527E-07 NA NA 1.046256E-06 8.843737E-07 1.481419E-06 1.556734E-06 NA 2.037083E-06 2.177022E-06 1.776492E-06 1.533264E-06 1.707335E-06 NA 2.181976E-06 2.284747E-06 2.121459E-06 2.832282E-06 2.652490E-06 2.435472E-06 2.779851E-06 2.944212E-06 2.582309E-06 2.535140E-06 2.316382E-06 2.039765E-06 +Q03322 YDR468C 1.459900E-07 1.521146E-07 NA 1.473964E-07 1.558800E-07 1.412293E-07 NA 1.696964E-07 NA NA NA 1.881862E-07 1.179410E-07 1.431747E-07 1.399845E-07 NA NA 1.905694E-07 1.631889E-07 1.882775E-07 NA 1.800992E-07 NA 1.700934E-07 NA NA 1.416147E-07 +Q03654 YMR213W NA NA NA NA NA NA NA 1.581773E-08 NA NA 2.278741E-08 NA NA NA NA NA NA NA NA NA NA 2.670542E-08 2.100085E-08 NA NA NA NA +Q03944 YDR200C NA NA NA NA NA 2.454546E-08 NA NA NA NA NA NA NA NA 2.145375E-08 NA NA NA 2.911539E-08 NA NA NA NA NA NA NA NA +Q04201 YML101C 9.006586E-07 8.969601E-07 8.904040E-07 1.058475E-06 1.139527E-06 NA 1.477062E-06 2.122666E-06 1.797802E-06 1.994394E-06 NA NA 1.505430E-06 1.723975E-06 NA NA NA NA 1.709011E-06 1.537496E-06 NA NA 1.633852E-06 2.316552E-06 1.704262E-06 NA NA +Q04598 YDR115W 2.450114E-07 2.423171E-07 NA 2.681213E-07 2.670668E-07 NA 5.048762E-07 4.880231E-07 NA 6.469005E-07 7.236420E-07 5.916191E-07 4.826314E-07 5.831177E-07 5.181141E-07 6.251667E-07 7.818862E-07 6.931834E-07 8.246866E-07 9.154742E-07 6.998720E-07 9.704556E-07 1.006699E-06 8.785013E-07 9.019340E-07 9.971518E-07 8.960221E-07 +Q06406 YDR378C 3.936863E-07 3.650289E-07 NA 4.264854E-07 4.056664E-07 4.160444E-07 3.836175E-07 NA 5.472789E-07 5.192227E-07 NA NA 3.678276E-07 NA NA NA NA 5.181628E-07 4.443679E-07 4.597651E-07 NA NA 5.746247E-07 4.570960E-07 5.416527E-07 NA NA +Q06538 YLR241W NA NA NA NA NA NA 7.038226E-10 NA 1.015202E-09 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +Q07951 YLR021W 4.868328E-08 4.419239E-08 5.898172E-08 4.238188E-08 5.228923E-08 NA 6.284163E-08 6.454192E-08 7.649068E-08 NA NA NA 5.578673E-08 NA 8.805995E-08 NA NA NA NA NA 3.893064E-08 NA NA 1.017125E-07 NA NA 8.111472E-08 +Q08561 YOR189W NA NA NA NA NA NA NA NA NA NA 1.104681E-07 NA NA 1.282193E-07 NA NA 1.396044E-07 NA NA 1.474905E-07 NA NA NA NA NA 1.560762E-07 1.081203E-07 +Q08963 YPL213W NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 6.366482E-08 NA NA 7.171313E-08 NA NA NA NA NA +Q12163 YDR162C NA 1.449848E-07 NA 1.150469E-07 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +Q12284 YPR037C NA NA 7.071962E-08 1.046864E-07 NA 9.397060E-08 NA 1.358540E-07 NA 1.649829E-07 NA NA NA 1.273355E-07 NA 1.221346E-07 1.430550E-07 NA 1.639551E-07 1.580541E-07 NA 1.163513E-07 NA NA 9.936705E-08 1.119660E-07 NA +Q12328 YDL217C NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 4.554022E-08 NA NA NA NA NA NA 3.757427E-08 NA NA +Q12383 YOL125W NA NA NA NA NA NA NA NA NA 4.318030E-08 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +Q12415 YOR110W NA NA 2.579360E-08 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.897616E-08 NA NA +Q3E7A3 YJL133C-A 9.079882E-08 8.424341E-08 7.537267E-08 NA 8.163840E-08 NA 1.461371E-07 1.189806E-07 NA 1.658266E-07 NA 1.796512E-07 1.875699E-07 2.150203E-07 2.085656E-07 2.265006E-07 NA 2.106632E-07 2.727595E-07 3.300304E-07 2.176966E-07 2.701032E-07 2.765683E-07 NA 2.509335E-07 2.206108E-07 NA +Q96VH5 YCL057C-A NA 1.226645E-07 NA 1.913602E-07 1.258100E-07 8.971872E-08 2.956482E-07 1.630755E-07 NA 3.897728E-07 NA NA 2.981693E-07 1.075108E-07 NA NA NA NA 4.467188E-07 2.076570E-07 NA NA 1.577656E-07 NA NA NA NA +P04039 YLR395C NA NA 2.570308E-06 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P04710 YMR056C NA NA 4.252916E-08 NA NA NA NA NA 5.769500E-08 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P17898 YNL130C NA NA 1.811512E-07 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P32607 YOL067C NA NA NA NA NA NA NA 4.126596E-08 2.598308E-08 NA NA NA 2.325723E-08 NA NA NA NA NA NA NA NA NA NA NA 3.105046E-08 NA NA +P32656 YER163C NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.390109E-07 NA NA NA NA 2.934181E-07 NA +P33296 YER100W NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 9.540362E-08 NA NA NA NA NA NA NA +P33331 YER009W 1.872796E-05 1.448126E-05 2.143111E-05 2.004555E-05 2.034578E-05 1.714209E-05 2.441476E-05 NA NA 2.883625E-05 2.987127E-05 2.984638E-05 2.394983E-05 NA NA 2.844178E-05 2.797466E-05 2.644322E-05 NA 2.645629E-05 2.744274E-05 NA 2.685991E-05 2.805004E-05 NA 2.551539E-05 2.418180E-05 +P34164 YGL208W NA NA NA NA 1.171671E-08 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P38210 YBL006C 2.304822E-07 NA NA NA NA NA NA NA NA NA 6.130626E-07 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P38374 YBR162W-A NA 4.115504E-07 6.975542E-07 NA 5.738836E-07 NA NA NA NA NA NA NA NA NA NA NA 8.161977E-07 NA NA NA NA NA 9.637973E-07 NA NA NA NA +P38744 YHL018W 2.180982E-07 1.783163E-07 1.750277E-07 NA NA 2.076804E-07 NA NA NA 1.828806E-07 NA 1.852004E-07 1.386135E-07 NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P40006 YEL001C NA NA 5.809661E-07 NA 1.130785E-06 NA 1.411436E-06 1.407523E-06 NA 1.760985E-06 NA 2.042539E-06 1.559571E-06 1.167735E-06 NA 1.398379E-06 NA 1.219773E-06 1.550989E-06 NA 1.383331E-06 NA NA 1.252890E-06 1.197567E-06 NA 8.619409E-07 +P40159 YNL208W 1.254709E-05 1.048135E-05 1.023165E-05 9.452359E-06 1.009775E-05 9.541383E-06 1.027382E-05 1.020824E-05 1.011841E-05 1.233241E-05 NA NA 6.849209E-06 6.799530E-06 NA NA NA 6.602900E-06 6.807002E-06 5.541192E-06 6.893505E-06 NA 5.341122E-06 4.934298E-06 4.842322E-06 NA NA +P40554 YIL008W NA NA NA NA NA NA NA 1.648176E-07 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P47131 YJR085C NA NA 8.967690E-07 NA NA NA NA NA NA NA NA NA 9.536378E-07 NA NA NA NA NA NA NA NA NA NA 5.647060E-07 NA NA NA +P53039 YGR172C 3.531179E-07 NA 2.893584E-07 3.424425E-07 2.767618E-07 NA NA 4.246948E-07 2.774794E-07 4.626320E-07 NA NA 3.920987E-07 3.376649E-07 NA NA NA NA NA 3.759475E-07 3.096874E-07 NA NA NA NA NA NA +P53082 YGL220W NA NA NA 7.783963E-07 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P53130 YGL121C NA NA NA NA 3.372555E-06 NA NA 2.840330E-06 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P53253 YGR089W NA NA NA NA NA NA NA NA NA NA 5.721364E-09 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA +P53262 YGR106C NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 8.044707E-08 NA NA NA +P53438 YMR016C 2.190112E-08 NA NA NA NA NA NA NA NA NA NA NA 2.766756E-08 2.052274E-08 NA NA NA 3.655315E-08 NA NA NA NA NA NA 3.078036E-08 NA NA +Q02889 YPL098C NA 1.597427E-06 1.255874E-06 1.981667E-06 1.462457E-06 1.065642E-06 2.656030E-06 1.956099E-06 1.782123E-06 3.026601E-06 1.960769E-06 2.585355E-06 2.648210E-06 1.295550E-06 2.363607E-06 2.849543E-06 2.048460E-06 3.001194E-06 NA 2.134981E-06 2.859425E-06 NA NA 2.524753E-06 1.836568E-06 1.020416E-06 2.281043E-06 +Q12245 YPL144W NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.552430E-08 NA NA NA NA NA +Q12522 YPR016C NA NA NA NA 1.149350E-06 NA 1.618730E-06 NA 1.650713E-06 NA NA NA NA NA NA 2.301535E-06 NA 2.397043E-06 NA 1.607948E-06 NA NA NA 2.660426E-06 NA NA NA +Q6WNK7 YBR111W-A NA 1.302346E-07 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.261583E-07 NA NA NA NA NA NA 2.276456E-07 NA NA diff --git a/literature/xia2022/data/fermentationData.txt b/literature/xia2022/data/fermentationData.txt new file mode 100644 index 0000000..b48a1b3 --- /dev/null +++ b/literature/xia2022/data/fermentationData.txt @@ -0,0 +1,10 @@ +Condition Ptot D Glucose CO2 Oxygen Glycerol Acetate Ethanol Formate +mu003 0.299 0.027 0.325917121149714 0.9570207835601432 0.840845047999322 NA NA NA NA +mu004 0.312 0.044 0.494144704652056 1.5648471138116322 1.54277114377377 NA NA NA NA +mu010 0.371 0.10225 1.1441811165618 2.68608596738391 2.42077135288014 NA NA NA NA +mu015 0.419 0.152 1.60320845720337 3.8796884681049018 4.05760576525164 NA NA NA NA +mu021 0.32 0.21425 2.37362494155752 5.923104157760982 5.62833319678978 NA NA NA NA +mu025 0.378 0.254 2.71217025984321 6.813127576101639 5.90540962542369 NA NA NA NA +mu028 0.391 0.28425 3.14269663461493 8.540704142263435 7.98407343919044 NA NA NA NA +mu033 0.419 0.33375000000000005 4.88134659826695 12.239522291088242 9.64295113005445 NA NA 2.193290332967266 NA +mu038 0.391 0.37849999999999995 6.70691099812471 14.385452880294718 9.5922636191899 NA NA 5.831389975022448 NA diff --git a/literature/xia2022/data/ribosome_core.tsv b/literature/xia2022/data/ribosome_core.tsv new file mode 100644 index 0000000..14586c0 --- /dev/null +++ b/literature/xia2022/data/ribosome_core.tsv @@ -0,0 +1,49 @@ +uniprot gene gene_name this_study_uniprot this_study_gene_name +P14126 YOR063W RPL3 P14126 RPL3 +P26783 YJR123W RPS5 P26783 RPS5 +P05755 YBR189W RPS9B P05755 RPS9B +P26786 YOR096W RPS7A P26786 RPS7A +P05317 YLR340W RPP0 P05317 RPP0 +P04147 YER165W PAB1 P04147 PAB1 +P05750 YNL178W RPS3 P05750 RPS3 +P25443 YGL123W RPS2 P25443 RPS2 +P48589 YOR369C RPS12 P48589 RPS12 +Q3E7X9 YOR167C RPS28A Q3E7X9 RPS28A +P41805 YLR075W RPL10 P41805 RPL10 +P05738 YGL147C RPL9A P51401 RPL9B +P26785 YNL069C RPL16B P26785 RPL16B +Q12672 YPL079W RPL21B Q02753 RPL21A +P04449 YGL031C RPL24A P04449 RPL24A +P38061 YBL092W RPL32 P38061 RPL32 +P05748 YLR029C RPL15A P05748 RPL15A +P05756 YDR064W RPS13 P05756 RPS13 +P05744 YPL143W RPL33A P41056 RPL33B +P41057 YLR388W RPS29A P41057 RPS29A +P05739 YLR448W RPL6B P05739 RPL6B +P87262 YER056C-A RPL34A P87262 RPL34A +P38754 YHL001W RPL14B P38754 RPL14B +P14120 YGL030W RPL30 P14120 RPL30 +P49167 YLR325C RPL38 P49167 RPL38 +P41058 YDL061C RPS29B P41058 RPS29B +P46784 YMR230W RPS10B P46784 RPS10B +P38701 YHL015W RPS20 P38701 RPS20 +P40212 YMR142C RPL13B P40212 RPL13B +P02406 YGL103W RPL28 P02406 RPL28 +P04456 YOL127W RPL25 P04456 RPL25 +P26321 YPL131W RPL5 P26321 RPL5 +P49166 YLR185W RPL37A P49166 RPL37A +P05740 YKL180W RPL17A P05740 RPL17A +P05743 YLR344W RPL26A P53221 RPL26B +P0C2H8 YDL075W RPL31A P0C2H8 RPL31A +P04650 YJL189W RPL39 P04650 RPL39 +O14455 YPL249C-A RPL36B O14455 RPL36B +P39938 YGL189C RPS26A P39938 RPS26A +P38011 YMR116C ASC1 P38011 ASC1 +P16521 YLR249W YEF3 P16521 YEF3 +P05749 YLR061W RPL22A P05749 RPL22A +P33442 YLR441C RPS1A P23248 RPS1B +P07280 YOL121C RPS19A P07281 RPS19B +Q01855 YOL040C RPS15 Q01855 RPS15 +P05759 YLR167W RPS31 P05759 RPS31 +P46654 YLR048W RPS0B P46654 RPS0B +P29453 YLL045C RPL8B P17076 RPL8A diff --git a/literature/xia2022/results/enzymeUsage/capUsage.tsv b/literature/xia2022/results/enzymeUsage/capUsage.tsv new file mode 100644 index 0000000..0185691 --- /dev/null +++ b/literature/xia2022/results/enzymeUsage/capUsage.tsv @@ -0,0 +1,218 @@ +protID geneID protName mu003 mu004 mu010 mu015 mu021 mu025 mu028 mu033 mu038 GOterm +P00401 Q0045 COX1 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +P00163 Q0105 COB 13.608 24.867 31.127 39.163 73.326 64.768 70.125 68.971 85.851 ETC +P00410 Q0250 COX2 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +P00420 Q0275 COX3 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +P31373 YAL012W CYS3 1.358 2.249 4.161 4.85 8.184 7.563 7.653 8.806 8.874 Amino acid metabolism +P00549 YAL038W CDC19 1.593 2.331 5.362 7.114 17.44 18.059 20.552 31.696 37.651 Glycolysis +P39726 YAL044C GCV3 2.659 4.675 6.226 6.867 16.066 14.99 20.144 17.692 18.54 THF cycle +P07256 YBL045C COR1 13.608 24.867 31.127 39.163 73.326 64.768 70.125 68.971 85.851 ETC +P07702 YBR115C LYS2 5.364 7.077 11.386 14.986 32.466 37.447 35.352 33.03 28.353 Amino acid metabolism +P20049 YBR166C TYR1 8.115 15.846 27.173 34.242 0.001 72.59 89.063 99.01 99.01 Amino acid metabolism +P12709 YBR196C PGI1 0.457 0.741 1.837 1.95 5.097 4.973 5.93 10.013 15.261 Glycolysis +P32473 YBR221C PDB1 68.229 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 Glycolysis +P33734 YBR248C HIS7 7.124 8.882 12.927 16.734 31.739 33.656 38.216 43.085 44.845 Amino acid metabolism +P32449 YBR249C ARO4 0.354 0.455 0.789 1.042 2.131 2.35 2.525 2.712 3.262 Amino acid metabolism +P04173 YCL018W LEU2 0.149 0.245 0.479 0.603 0.951 0.898 0.903 1.209 1.507 Amino acid metabolism +P00815 YCL030C HIS4 4.517 4.867 7.416 10.09 20.573 23.961 19.646 19.215 20.15 Amino acid metabolism +P25379 YCL064C CHA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 Amino acid metabolism +P08679 YCR005C CIT2 0.0 0.0 0.0 0.0 100.0 0.0 44.83 29.739 31.189 TCA cycle +P25613 YCR010C ADY2 0.0 0.0 0.001 0.0 0.001 0.001 0.001 0.001 0.001 Nitrogen metabolism +P00560 YCR012W PGK1 0.239 0.359 0.994 1.472 3.754 4.319 4.399 7.34 11.626 Glycolysis +P16120 YCR053W THR4 0.009 0.014 0.022 0.029 0.054 0.056 0.062 0.071 0.082 Amino acid metabolism +P21954 YDL066W IDP1 0.0 0.0 0.0 19.978 0.0 0.0 0.0 0.0 0.0 TCA cycle +P07255 YDL067C COX9 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +P32419 YDL078C MDH3 0.0 0.0 0.0 0.0 0.001 0.0 0.001 0.001 0.001 TCA cycle +Q12122 YDL131W LYS21 0.0 0.0 0.0 0.0 100.0 100.0 100.0 100.0 100.0 Amino acid metabolism +P48570 YDL182W LYS20 33.187 44.857 72.213 90.268 100.0 100.0 100.0 100.0 100.0 Amino acid metabolism +P00912 YDR007W TRP1 0.0 3.514 7.002 0.0 0.0 0.0 0.0 17.152 0.0 Amino acid metabolism +P48015 YDR019C GCV1 2.659 4.675 6.226 6.867 16.066 14.99 20.144 17.692 18.54 THF cycle +P00942 YDR050C TPI1 0.014 0.022 0.052 0.063 0.147 0.137 0.142 0.216 0.334 Glycolysis +P08566 YDR127W ARO1 7.01 9.906 17.465 22.242 43.282 48.432 45.543 50.74 54.63 Amino acid metabolism +P19262 YDR148C KGD2 3.687 7.507 11.719 14.143 28.098 27.009 23.182 26.488 32.854 TCA cycle +P13663 YDR158W HOM2 57.231 85.509 99.01 99.01 100.0 99.01 100.0 99.01 99.01 Amino acid metabolism +P49367 YDR234W LYS4 87.051 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 Amino acid metabolism +P32264 YDR300C PRO1 20.617 33.842 0.0 74.117 100.0 100.0 100.0 100.0 100.0 Amino acid metabolism +P07285 YDR354W TRP4 15.57 26.046 29.455 45.749 0.008 100.0 100.0 100.0 100.0 Amino acid metabolism +Q12359 YDR384C ATO3 0.01 0.016 0.038 0.057 0.079 0.094 0.106 0.124 0.141 Nitrogen metabolism +Q04409 YDR516C EMI2 17.393 36.385 100.0 100.0 100.0 100.0 100.0 100.0 100.0 Glycolysis +P00128 YDR529C QCR7 13.608 24.867 31.127 39.163 73.326 64.768 70.125 68.971 85.851 ETC +P08067 YEL024W RIP1 13.608 24.867 31.127 39.163 73.326 64.768 70.125 68.971 85.851 ETC +P32626 YEL038W UTR4 0.0 0.0 0.004 0.001 0.076 0.071 0.057 0.086 0.098 Amino acid metabolism +P37303 YEL046C GLY1 0.0 0.0 0.0 0.0 0.431 0.0 0.0 0.0 0.0 Amino acid metabolism +P32263 YER023W PRO3 0.021 0.033 0.056 0.07 0.115 0.116 0.125 0.136 0.163 Amino acid metabolism +P10869 YER052C HOM3 0.365 0.484 0.925 1.347 2.768 3.249 2.636 2.399 2.573 Amino acid metabolism +P00498 YER055C HIS1 2.085 2.416 3.219 4.046 8.102 10.085 11.007 9.462 9.276 Amino acid metabolism +P28240 YER065C ICL1 0.0 0.0 0.0 0.0 0.921 0.0 0.0 0.0 0.0 TCA cycle +Q01217 YER069W ARG5,6 15.102 11.588 30.838 22.93 63.27 81.533 97.741 92.352 100.0 Amino acid metabolism +P00899 YER090W TRP2 0.141 0.173 0.232 0.315 0.615 0.688 0.803 0.82 0.864 Amino acid metabolism +P05694 YER091C MET6 10.963 12.103 15.561 17.721 28.57 24.53 22.072 23.115 26.782 Amino acid metabolism +P16387 YER178W PDA1 68.229 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 Glycolysis +P09624 YFL018C LPD1 20.995 31.634 48.342 68.548 99.669 100.0 89.343 100.0 100.0 THF cycle +P43567 YFL030W AGX1 0.0 0.0 0.0 0.0 0.08 0.0 0.0 0.0 0.0 Amino acid metabolism +P38635 YFR025C HIS2 0.143 0.218 0.384 0.478 0.872 0.853 1.035 0.0 1.296 Amino acid metabolism +P39692 YFR030W MET10 0.692 0.741 1.022 1.156 2.037 1.946 1.961 2.116 2.171 Amino acid metabolism +P00127 YFR033C QCR6 13.608 24.867 31.127 39.163 73.326 64.768 70.125 68.971 85.851 ETC +P19955 YFR049W YMR31 3.687 7.507 11.719 14.143 28.098 27.009 23.182 26.488 32.854 Ribosome +P04806 YFR053C HXK1 0.0 0.0 0.235 1.888 10.817 9.354 12.339 21.53 34.758 Glycolysis +P07264 YGL009C LEU1 3.951 5.919 9.945 11.368 17.963 17.176 17.167 20.699 25.443 Amino acid metabolism +P00931 YGL026C TRP5 0.151 0.188 0.281 0.378 2.189 0.984 1.017 0.917 1.014 Amino acid metabolism +P53128 YGL125W MET13 3.054 3.661 4.981 5.016 7.298 6.234 6.769 6.191 7.348 THF cycle +P28777 YGL148W ARO2 4.072 4.935 6.964 8.658 15.666 15.491 17.436 16.648 17.785 Amino acid metabolism +P50113 YGL154C LYS5 5.364 7.077 11.386 14.986 32.466 37.447 35.352 33.03 28.353 Amino acid metabolism +P04037 YGL187C COX4 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +P32799 YGL191W COX13 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +P53090 YGL202W ARO8 4.537 4.61 6.195 7.928 13.136 17.101 19.3 19.556 22.211 Amino acid metabolism +P32582 YGR155W CYS4 0.293 0.426 0.767 0.93 1.55 1.474 1.555 1.639 1.773 Amino acid metabolism +P22289 YGR183C QCR9 13.608 24.867 31.127 39.163 73.326 64.768 70.125 68.971 85.851 ETC +P00359 YGR192C TDH3 0.0 0.0 0.0 0.0 42.315 86.733 93.274 100.0 100.0 Glycolysis +P07245 YGR204W ADE3 2.977 3.853 5.697 6.78 9.037 11.329 12.271 12.611 12.678 THF cycle +P42941 YGR208W SER2 0.976 1.648 2.691 3.625 5.785 5.836 6.585 7.054 7.092 Amino acid metabolism +P16861 YGR240C PFK1 2.805 4.342 9.358 10.249 21.355 20.033 21.105 33.736 48.245 Glycolysis +P53312 YGR244C LSC2 5.408 7.243 10.895 15.587 21.475 18.332 26.13 34.209 41.767 TCA cycle +P53315 YGR248W SOL4 0.0 0.0 100.0 100.0 0.013 0.027 0.013 0.006 0.021 PP shunt +P00924 YGR254W ENO1 0.582 0.945 2.944 4.75 16.654 40.558 43.345 68.731 100.0 Glycolysis +P51601 YGR267C FOL2 1.332 1.865 2.745 3.549 6.337 7.058 7.384 8.231 10.006 THF cycle +P37299 YHR001W-A QCR10 13.608 24.867 31.127 39.163 73.326 64.768 70.125 68.971 85.851 ETC +P04076 YHR018C ARG4 0.018 0.018 0.026 0.037 0.086 0.138 0.137 0.122 0.126 Amino acid metabolism +P17423 YHR025W THR1 1.908 3.113 4.125 0.001 0.001 0.002 12.347 0.002 0.002 Amino acid metabolism +P00427 YHR051W COX6 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +P38840 YHR137W ARO9 1.972 3.065 2.782 3.602 5.332 6.42 9.481 76.308 0.001 Amino acid metabolism +P38858 YHR163W SOL3 61.807 65.313 100.0 100.0 100.0 100.0 100.0 100.0 100.0 PP shunt +P38720 YHR183W GND1 2.712 2.202 4.259 12.59 8.494 11.107 6.566 4.592 8.313 PP shunt +P38891 YHR208W BAT1 0.055 0.082 0.311 0.185 0.449 0.455 0.508 0.697 0.736 Amino acid metabolism +P40545 YIL020C HIS6 6.121 10.5 21.77 0.0 53.901 0.001 53.193 53.367 59.158 Amino acid metabolism +P40510 YIL074C SER33 0.069 0.099 0.187 0.222 0.369 0.375 0.366 0.419 0.432 Amino acid metabolism +P40495 YIL094C LYS12 2.998 4.818 8.437 10.42 16.325 16.629 17.004 17.034 21.367 Amino acid metabolism +P07172 YIL116W HIS5 0.013 0.02 0.034 0.045 0.102 0.125 0.135 0.136 0.147 Amino acid metabolism +P20967 YIL125W KGD1 3.687 7.507 11.719 14.143 28.098 27.009 23.182 26.488 32.854 TCA cycle +P38998 YIR034C LYS1 0.001 0.001 0.002 0.003 0.004 0.005 0.006 0.007 0.008 Amino acid metabolism +P47052 YJL045W YJL045W 11.793 16.033 21.802 18.384 32.831 27.303 35.978 36.264 43.55 ETC +P00360 YJL052W TDH1 9.739 11.221 35.739 52.662 100.0 100.0 100.0 100.0 100.0 Glycolysis +P05150 YJL088W ARG3 0.01 0.01 0.017 0.022 0.042 0.043 0.043 0.057 0.069 Amino acid metabolism +P46969 YJL121C RPE1 3.581 2.933 5.045 20.231 8.697 15.594 7.289 0.778 6.821 PP shunt +P07259 YJL130C URA2 0.053 0.082 0.143 0.177 0.329 0.364 0.336 0.376 0.39 Amino acid metabolism +P08525 YJL166W QCR8 13.608 24.867 31.127 39.163 73.326 64.768 70.125 68.971 85.851 ETC +P39533 YJL200C ACO2 0.0 18.775 100.0 100.0 100.0 100.0 100.0 100.0 100.0 TCA cycle +P00358 YJR009C TDH2 0.0 0.0 0.0 0.0 100.0 100.0 100.0 100.0 100.0 Glycolysis +P08536 YJR010W MET3 0.557 0.724 1.367 1.5 2.261 2.238 2.366 2.443 2.872 Amino acid metabolism +P39522 YJR016C ILV3 3.944 5.168 8.049 10.196 18.382 18.316 20.437 19.935 21.159 Amino acid metabolism +P47095 YJR024C MDE1 0.05 0.086 1.104 0.207 0.0 0.0 0.0 0.0 0.0 Amino acid metabolism +P47169 YJR137C MET5 0.692 0.741 1.022 1.156 2.037 1.946 1.961 2.116 2.171 Amino acid metabolism +P31116 YJR139C HOM6 1.134 1.675 2.885 3.634 6.026 6.106 6.761 7.412 8.494 Amino acid metabolism +P47176 YJR148W BAT2 0.201 0.349 1.016 0.831 1.593 1.518 1.546 12.896 16.894 Amino acid metabolism +Q02196 YKL001C MET14 4.454 6.394 10.592 11.299 16.887 15.087 16.376 18.067 20.256 Amino acid metabolism +P14540 YKL060C FBA1 1.235 1.737 3.824 4.452 10.112 9.606 11.765 21.873 33.158 Glycolysis +P17505 YKL085W MDH1 4.476 7.412 12.074 15.104 26.778 22.967 21.01 22.864 25.994 TCA cycle +P33421 YKL141W SDH3 11.793 16.033 21.802 18.384 32.831 27.303 35.978 36.264 43.55 ETC +P00950 YKL152C GPM1 0.268 0.356 1.052 1.41 3.831 4.939 5.129 9.16 11.793 Glycolysis +P00937 YKL211C TRP3 3.852 4.705 6.04 7.353 44.849 18.782 21.114 22.564 26.585 Amino acid metabolism +Q02046 YKR080W MTD1 30.558 39.783 75.119 91.459 100.0 100.0 100.0 100.0 100.0 THF cycle +P21801 YLL041C SDH2 11.793 16.033 21.802 18.384 32.831 27.303 35.978 36.264 43.55 ETC +Q07938 YLR017W MEU1 0.486 0.783 7.005 1.143 100.0 100.0 100.0 100.0 100.0 Nitrogen metabolism +P23542 YLR027C AAT2 0.434 0.59 0.863 1.088 1.967 2.028 1.914 1.968 2.365 Amino acid metabolism +Q01519 YLR038C COX12 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +P37291 YLR058C SHM2 0.036 0.048 0.079 0.09 0.121 0.144 0.139 0.135 0.137 THF cycle +Q06236 YLR164W SHH4 11.793 16.033 21.802 18.384 32.831 27.303 35.978 36.264 43.55 ETC +P41939 YLR174W IDP2 2.75 4.931 9.569 10.756 24.133 23.738 30.958 53.31 80.92 TCA cycle +P06106 YLR303W MET17 0.021 0.031 0.055 0.068 0.111 0.109 0.114 0.148 0.181 Amino acid metabolism +P19414 YLR304C ACO1 7.768 14.707 19.034 20.66 39.888 30.7 29.383 29.342 33.496 TCA cycle +P15019 YLR354C TAL1 0.33 0.358 0.742 2.427 1.704 2.6 1.609 1.128 2.565 PP shunt +P06168 YLR355C ILV5 1.091 1.509 2.271 2.844 4.882 4.895 5.233 7.25 8.765 Amino acid metabolism +P04039 YLR395C COX8 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +P07991 YLR438W CAR2 0.0 0.0 3.424 0.0 3.62 5.221 8.616 25.203 16.869 Amino acid metabolism +Q03677 YMR009W ADI1 0.0 0.0 0.004 0.001 0.076 0.071 0.057 0.086 0.098 Amino acid metabolism +Q04728 YMR062C ARG7 3.718 3.977 11.57 9.153 28.809 45.545 56.791 46.282 41.284 Amino acid metabolism +P07342 YMR108W ILV2 0.327 0.415 0.659 0.858 1.588 1.647 1.885 1.973 2.427 Amino acid metabolism +Q12676 YMR113W FOL3 0.034 0.06 0.0 0.0 0.0 0.0 0.0 0.0 0.0 THF cycle +P54114 YMR169C ALD3 0.0 0.0 0.011 0.003 0.615 1.168 0.665 0.888 0.567 Amino acid metabolism +P49095 YMR189W GCV2 2.659 4.675 6.226 6.867 16.066 14.99 20.144 17.692 18.54 THF cycle +P16862 YMR205C PFK2 2.805 4.342 9.358 10.249 21.355 20.033 21.105 33.736 48.245 Glycolysis +P10174 YMR256C COX7 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +Q03266 YMR289W ABZ2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 THF cycle +P42222 YMR323W ERR3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.009 Glycolysis +P28834 YNL037C IDH1 0.0 8.87 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TCA cycle +P00424 YNL052W COX5A 14.125 22.142 42.606 37.697 74.185 60.796 68.589 69.456 85.843 ETC +P06208 YNL104C LEU4 0.001 0.002 0.0 0.008 0.007 0.007 0.008 0.0 0.0 Amino acid metabolism +P30952 YNL117W MLS1 0.0 0.0 0.004 0.0 0.0 0.0 0.0 0.0 0.0 TCA cycle +P11412 YNL241C ZWF1 0.443 0.479 0.851 2.856 2.066 2.958 1.838 0.862 1.733 PP shunt +P53848 YNL256W FOL1 3.068 4.651 0.0 0.0 0.0 0.0 18.68 16.823 22.431 THF cycle +P08465 YNL277W MET2 18.817 21.326 29.411 40.734 84.452 88.264 89.858 99.01 99.01 Amino acid metabolism +P32452 YNL316C PHA2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 Amino acid metabolism +P00890 YNR001C CIT1 2.764 5.135 7.848 9.475 15.394 11.944 12.291 13.443 16.832 TCA cycle +P37254 YNR033W ABZ1 0.0 0.0 0.001 0.001 0.002 0.002 0.003 0.003 0.003 THF cycle +P38999 YNR050C LYS9 0.583 0.736 1.233 1.446 2.45 2.357 2.551 3.211 3.665 Amino acid metabolism +P22768 YOL058W ARG1 12.629 15.061 22.284 29.452 68.684 99.01 99.01 99.01 99.01 Amino acid metabolism +P32179 YOL064C MET22 4.43 5.62 10.566 13.057 25.691 27.853 31.977 29.301 29.123 Amino acid metabolism +P22133 YOL126C MDH2 0.002 0.004 0.019 0.02 0.033 0.071 0.08 0.0 0.32 TCA cycle +P18544 YOL140W ARG8 32.822 33.159 84.023 68.386 100.0 100.0 100.0 100.0 100.0 Amino acid metabolism +P07143 YOR065W CYT1 13.608 24.867 31.127 39.163 73.326 64.768 70.125 68.971 85.851 ETC +P06785 YOR074C CDC21 0.192 0.231 0.35 0.361 0.545 0.632 0.761 0.708 0.807 THF cycle +Q12189 YOR095C RKI1 64.539 63.361 100.0 100.0 100.0 100.0 100.0 100.0 100.0 PP shunt +Q12166 YOR108W LEU9 0.0 0.0 43.541 0.0 34.958 35.108 52.347 97.29 91.343 Amino acid metabolism +Q12375 YOR130C ORT1 0.001 0.001 0.005 0.004 0.007 0.009 0.01 0.011 0.012 Amino acid metabolism +P28241 YOR136W IDH2 0.0 8.87 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TCA cycle +P53598 YOR142W LSC1 5.408 7.243 10.895 15.587 21.475 18.332 26.13 34.209 41.767 TCA cycle +P33330 YOR184W SER1 62.684 97.376 100.0 100.0 100.0 100.0 100.0 100.0 100.0 Amino acid metabolism +P06633 YOR202W HIS3 0.038 0.042 0.065 0.074 0.147 0.186 0.224 0.224 0.261 Amino acid metabolism +P07807 YOR236W DFR1 0.042 0.059 0.0 0.0 0.0 0.0 0.0 0.0 0.0 Amino acid metabolism +P54885 YOR323C PRO2 1.217 1.757 0.0 3.417 4.348 4.493 4.633 5.459 6.697 Amino acid metabolism +P07262 YOR375C GDH1 17.644 16.05 16.434 17.167 24.941 25.795 29.696 36.38 42.551 Nitrogen metabolism +P46151 YPL023C MET12 3.644 5.082 7.916 11.611 18.611 19.445 23.047 24.847 29.799 THF cycle +P08417 YPL262W FUM1 0.986 1.647 1.879 2.137 3.758 3.01 3.257 3.222 3.619 TCA cycle +P43635 YPR001W CIT3 0.0 0.0 0.0 0.0 0.009 0.0 0.0 0.0 0.0 TCA cycle +P32288 YPR035W GLN1 0.899 0.96 1.255 1.223 1.849 1.89 1.776 1.787 2.245 Nitrogen metabolism +P32178 YPR060C ARO7 1.391 1.822 3.245 4.127 6.98 6.615 7.27 7.442 8.192 Amino acid metabolism +P23254 YPR074C TKL1 2.326 1.458 1.728 6.58 2.774 5.095 2.24 2.758 3.165 PP shunt +Q06489 YPR118W MRI1 0.026 0.041 0.436 0.077 8.302 8.851 7.91 11.387 9.72 Amino acid metabolism +P49089 YPR145W ASN1 5.124 5.943 8.723 11.15 22.276 25.988 25.874 28.473 25.623 Amino acid metabolism +P18408 YPR167C MET16 0.001 99.01 99.01 99.01 99.01 99.01 99.01 99.01 99.01 Amino acid metabolism +P07257 YPR191W QCR2 13.608 24.867 31.127 39.163 73.326 64.768 70.125 68.971 85.851 ETC +P14126 YOR063W YOR063W 10.631 15.329 26.177 30.57 47.352 47.645 49.036 48.117 53.95 Ribosome +P26783 YJR123W YJR123W 12.907 18.758 29.861 34.611 60.986 54.396 58.287 55.099 62.594 Ribosome +P05755 YBR189W YBR189W 10.397 15.541 23.234 30.124 48.851 46.658 46.859 47.798 52.09 Ribosome +P26786 YOR096W YOR096W 14.342 20.335 33.181 37.867 66.61 61.927 64.538 64.755 74.085 Ribosome +P05317 YLR340W YLR340W 8.296 12.979 21.114 26.102 44.291 44.49 43.733 50.204 52.941 Ribosome +P04147 YER165W YER165W 43.411 64.626 99.01 99.01 99.01 99.01 99.01 99.01 99.01 Ribosome +P05750 YNL178W YNL178W 12.895 18.719 34.173 41.268 67.966 63.383 63.841 63.021 71.865 Ribosome +P25443 YGL123W YGL123W 12.038 18.608 29.716 36.342 60.742 54.716 54.896 55.098 63.072 Ribosome +P48589 YOR369C YOR369C 14.027 20.878 35.124 41.118 65.85 62.714 68.599 64.035 71.791 Ribosome +Q3E7X9 YOR167C YOR167C 39.372 60.217 80.649 99.01 99.01 99.01 99.01 99.01 99.01 Ribosome +P41805 YLR075W YLR075W 15.401 21.463 36.781 42.373 68.484 68.11 70.097 70.088 80.245 Ribosome +P05738 YGL147C YGL147C 30.828 38.639 52.983 60.504 92.764 89.39 83.003 78.758 79.981 Ribosome +P26785 YNL069C YNL069C 24.719 33.621 55.408 61.738 99.01 96.951 99.01 99.01 99.01 Ribosome +Q12672 YPL079W YPL079W 9.247 14.572 25.282 28.517 50.267 45.206 53.059 54.398 59.293 Ribosome +P04449 YGL031C YGL031C 10.202 13.574 23.135 28.299 46.192 45.901 47.997 49.454 54.882 Ribosome +P38061 YBL092W YBL092W 9.458 15.186 25.355 31.065 57.062 53.678 56.139 59.219 66.408 Ribosome +P05748 YLR029C YLR029C 12.333 17.521 30.328 33.63 56.271 56.04 58.985 58.451 68.027 Ribosome +P05756 YDR064W YDR064W 17.816 25.357 44.326 48.901 82.768 85.102 82.516 77.652 89.66 Ribosome +P05744 YPL143W YPL143W 68.387 99.01 99.01 99.01 99.01 99.01 99.01 99.01 99.01 Ribosome +P41057 YLR388W YLR388W 32.715 54.145 74.714 88.525 99.01 99.01 99.01 99.01 99.01 Ribosome +P05739 YLR448W YLR448W 11.862 17.691 31.134 34.795 54.901 53.885 55.77 58.643 65.359 Ribosome +P87262 YER056C-A YER056C-A 22.642 30.906 45.833 58.345 98.9 95.952 99.01 99.01 99.01 Ribosome +P38754 YHL001W YHL001W 6.375 10.235 20.775 25.866 41.294 37.926 40.895 38.267 42.4 Ribosome +P14120 YGL030W YGL030W 23.507 35.393 56.846 68.861 99.11 95.726 99.01 97.95 99.01 Ribosome +P49167 YLR325C YLR325C 11.244 17.356 27.002 31.711 50.217 48.3 49.624 49.252 53.574 Ribosome +P41058 YDL061C YDL061C 45.512 67.335 99.01 99.01 99.01 99.01 99.01 99.01 99.01 Ribosome +P46784 YMR230W YMR230W 0.004 0.006 0.014 0.021 0.03 0.036 0.04 0.047 0.053 Ribosome +P38701 YHL015W YHL015W 13.097 20.891 33.64 33.557 69.688 65.337 66.03 65.736 72.732 Ribosome +P40212 YMR142C YMR142C 10.786 16.075 25.072 29.425 48.7 49.854 52.697 53.344 60.955 Ribosome +P02406 YGL103W YGL103W 20.85 31.311 50.526 63.492 99.01 99.01 99.01 99.01 99.01 Ribosome +P04456 YOL127W YOL127W 11.264 16.48 26.329 31.974 49.224 47.791 51.378 47.329 57.413 Ribosome +P26321 YPL131W YPL131W 20.405 32.692 50.93 55.733 94.601 85.127 93.232 94.102 99.708 Ribosome +P49166 YLR185W YLR185W 35.852 58.529 89.858 99.01 99.01 99.01 99.01 99.01 99.01 Ribosome +P05740 YKL180W YKL180W 12.832 17.253 30.132 34.921 54.47 53.104 56.574 56.025 62.11 Ribosome +P05743 YLR344W YLR344W 4.23 6.78 14.259 18.792 32.419 32.699 37.296 40.406 43.015 Ribosome +P0C2H8 YDL075W YDL075W 13.345 19.396 35.464 38.662 61.218 58.882 64.765 65.336 73.837 Ribosome +P04650 YJL189W YJL189W 23.187 33.327 58.238 67.844 99.01 99.01 99.01 99.01 99.01 Ribosome +O14455 YPL249C-A YPL249C-A 9.891 14.925 22.898 26.237 43.367 42.299 43.812 43.938 49.436 Ribosome +P39938 YGL189C YGL189C 14.483 21.454 35.913 41.201 69.207 68.376 69.325 68.717 76.745 Ribosome +P38011 YMR116C YMR116C 12.02 16.676 28.841 31.488 56.2 50.924 51.532 52.891 60.518 Ribosome +P16521 YLR249W YLR249W 36.146 43.529 55.56 56.173 91.252 87.754 82.265 79.284 82.057 Ribosome +P05749 YLR061W YLR061W 28.158 46.232 65.814 74.582 99.01 99.01 99.01 99.01 99.01 Ribosome +P33442 YLR441C YLR441C 9.106 14.619 27.953 34.934 53.414 53.548 57.146 61.207 68.792 Ribosome +P07280 YOL121C YOL121C 11.663 16.645 27.786 32.565 51.233 52.826 51.818 52.039 60.774 Ribosome +Q01855 YOL040C YOL040C 18.361 25.078 42.251 50.599 82.488 78.954 78.247 78.774 89.452 Ribosome +P05759 YLR167W YLR167W 16.664 29.379 52.287 64.244 99.01 99.01 99.01 99.01 99.01 Ribosome +P46654 YLR048W YLR048W 41.904 64.729 99.01 99.01 99.01 99.01 99.01 99.01 99.01 Ribosome +P29453 YLL045C YLL045C 13.551 20.289 33.333 39.752 64.384 61.757 65.326 61.458 68.011 Ribosome diff --git a/literature/xia2022/results/enzymeUsage/enzymeUsages.tsv b/literature/xia2022/results/enzymeUsage/enzymeUsages.tsv new file mode 100644 index 0000000..1e48b4d --- /dev/null +++ b/literature/xia2022/results/enzymeUsage/enzymeUsages.tsv @@ -0,0 +1,1193 @@ +protID geneID protName capUse_mu003 capUse_mu004 capUse_mu010 capUse_mu015 capUse_mu021 capUse_mu025 capUse_mu028 capUse_mu033 capUse_mu038 absUse_mu003 absUse_mu004 absUse_mu010 absUse_mu015 absUse_mu021 absUse_mu025 absUse_mu028 absUse_mu033 absUse_mu038 UB_mu003 UB_mu004 UB_mu010 UB_mu015 UB_mu021 UB_mu025 UB_mu028 UB_mu033 UB_mu038 +P00401 Q0045 COX1 0.14125460670699755 0.22141946229568232 0.4260599361783745 0.376972581858826 0.7418501467795651 0.6079565893741123 0.685892024844011 0.6945609055734133 0.85842555544607 0.04862676696822848 0.08599940218629702 0.1648881463448846 0.23948649934308222 0.3726219340772127 0.4017931533085068 0.5085069038184111 0.5342376763626427 0.5627071797210487 0.34424906983100595 0.38840037499257357 0.38700692635848405 0.6352889065888843 0.5022873361888468 0.6608911891589997 0.7413804001206433 0.7691732605099456 0.6555107500599106 +P00856 Q0080 ATP8 0.16386432284501418 0.22431543814973962 0.31541513525434567 0.362919191725086 0.6034961681008579 0.5400857592618913 0.6547169428109808 0.7086700094404587 0.8113876061706357 0.007380401226097959 0.01308412941585167 0.025480181968232072 0.03671055013814416 0.054625609496606664 0.061633688731440185 0.07374288678166972 0.07850758845912441 0.082608002685939 0.04503970783852978 0.05832915257093221 0.08078300347789355 0.1011535101344342 0.09051525491621264 0.11411833708719134 0.11263323424174707 0.11078158721731611 0.10181077706598152 +P00854 Q0085 ATP6 0.16386432284501418 0.22431543814973964 0.3154151352543457 0.362919191725086 0.6034961681008579 0.5400857592618914 0.6547169428109809 0.7086700094404588 0.8113876061706358 0.03688806171044736 0.06539592612021089 0.12735276796523276 0.18348339032460614 0.2730248386708618 0.30805199388460636 0.36857510519749354 0.3923896112284544 0.41288393510102017 0.22511344184015425 0.2915355566234209 0.4037623871870877 0.5055764327382173 0.45240525640791335 0.5703760719512505 0.562953363655204 0.5536986270073311 0.5088615255656126 +P00163 Q0105 COB 0.13608151261417945 0.24866623746394367 0.3112731877806925 0.39162525147638194 0.7332575974400886 0.647676956717898 0.701245720233063 0.6897134137972912 0.8585061909343257 0.046097836710579536 0.0815268348352587 0.15631281534063182 0.22703153488116648 0.3532430005699279 0.3808971134097004 0.4820610063124144 0.502189529824181 0.5334424907088705 0.3387516483688485 0.32785647004885415 0.5021724371928944 0.5797162824033533 0.4817447535533922 0.5880973677678698 0.6874352204990266 0.7281133290700011 0.6213612625534088 +P61829 Q0130 OLI1 0.16386432284501418 0.22431543814973962 0.3154151352543457 0.3629191917250861 0.6034961681008579 0.5400857592618913 0.6547169428109808 0.7086700094404588 0.8113876061706358 0.09835886828116466 0.1743726556811974 0.339575286656669 0.4892428006215399 0.7279974305808504 0.8213943505105538 0.9827740613860794 1.0462734092311 1.100919774716937 0.600245780005415 0.7773546801749623 1.0765979456973138 1.3480764086792767 1.2063000049723356 1.5208591162135308 1.5010670980448566 1.4763901326333833 1.3568358283321034 +P00410 Q0250 COX2 0.14125460670699755 0.22141946229568232 0.42605993617837457 0.376972581858826 0.7418501467795651 0.6079565893741123 0.685892024844011 0.6945609055734133 0.85842555544607 0.02362530786729792 0.041782797412428095 0.08011088262584304 0.11635448189961956 0.1810383140716306 0.19521114681730864 0.2470580074386978 0.2595592996471243 0.27339120383501475 0.16725336198276042 0.188704267363054 0.1880272605408826 0.3086550255880244 0.24403623138383596 0.3210938909606644 0.3601995627444202 0.3737027200412874 0.3184798053838815 +P00420 Q0275 COX3 0.14125460670699755 0.2214194622956823 0.4260599361783745 0.37697258185882604 0.741850146779565 0.6079565893741123 0.685892024844011 0.6945609055734132 0.85842555544607 0.025108143902095592 0.04440528334936524 0.0851390204263869 0.12365743936963802 0.19240113470839446 0.20746352145389751 0.2625645362074724 0.2758504686276716 0.29055052852700836 0.17775097384382701 0.20054823947710015 0.19982874050552019 0.328027674479379 0.2593530991988399 0.34124726186039034 0.38280739051775114 0.3971580698166936 0.33846910391201884 +P31373 YAL012W CYS3 0.013584090196430261 0.022485999717354155 0.041606109782003985 0.04849996355284051 0.08184174569089342 0.07563206923966348 0.07653078779060063 0.08806156291957958 0.08873899932893219 0.0066546205386526685 0.010844566803730162 0.025201294447303613 0.037463048958341516 0.05280564631134828 0.062602726548811 0.07005836622637007 0.08225850388056878 0.09328792125481729 0.48988341820650044 0.48228083874610145 0.6057113866051472 0.7724345796162441 0.6452165195838925 0.8277272746622203 0.9154272188868611 0.9341022479431768 1.0512618122841733 +P31381 YAL022C FUN26 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P31382 YAL023C PMT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.030356415853226435 0.03581207858871802 0.04909914392143961 0.07704985162229838 0.052242346058642 0.05529527808380296 0.057741468413235054 0.06296267232403949 0.06633079503643496 +P39524 YAL026C DRS2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P39730 YAL035W FUN12 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.16670290720647196 0.18378012973163274 0.2783929272728924 0.3636213281928623 0.29099120201114553 0.3783182281273945 0.39014216854508765 0.4261110922751074 0.42378160324212966 +P00549 YAL038W CDC19 0.015925550348898483 0.02331007384389469 0.05361878117056902 0.07114137738055103 0.17440490084197294 0.18059190822993806 0.2055216614671681 0.31695562802905963 0.3765073167067795 0.03533696856662835 0.05268563508163826 0.1218484616065993 0.16051123639138762 0.2506748069344381 0.28022359108514994 0.33426988750106923 0.5671206576566681 0.82837145918136 2.2188852373991894 2.2602088450885596 2.2724959230047004 2.256228966903148 1.4373151541284543 1.5516951663656833 1.6264460160296463 1.7892746097717893 2.2001470420998173 +P06182 YAL039C CYC3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.009446682812752625 0.00937086379527131 1000.0 1000.0 0.016498324264950945 0.019615861742239102 0.023946812284136497 0.035178340173373235 0.0289646324355325 +P39726 YAL044C GCV3 0.026588943816182785 0.04675169665893909 0.062257198257902054 0.06867419132564019 0.16065716474193295 0.14990134725449059 0.2014412338795622 0.17691620463694674 0.18539561714546812 0.0013159262791631312 0.002568434165832345 0.0046291685489760655 0.0064096950369006535 0.010848201426193074 0.011431172738662315 0.015085477812470464 0.014516812056254888 0.014594012839605349 0.049491483688126836 0.05493777444205869 0.07435555531746892 0.09333484549540709 0.06752391929497058 0.07625797197976733 0.0748877353555617 0.08205473368618282 0.07871821925625327 +Q01574 YAL054C ACS1 0.0 0.0 0.0 0.0 0.04290602891329283 0.0 0.3069286007678082 1.0 0.00016449191860083177 0.0 0.0 0.0 0.0 0.06224712837021058 0.0 0.30176871143050776 0.0797046946182504 0.1644919186008318 2.575063464429911 2.3808954778027998 2.176942860122917 1.909562967114577 1.4507781294792732 1.194649230313243 0.983188633042367 0.0797046946182504 1000.0 +P39714 YAL060W BDH1 0.0 0.0 0.0 0.0 0.0 0.008151670265012864 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.003186165247863903 0.0 0.0 0.0 0.26318047306282316 0.22214686334044248 0.21992042146829452 0.26685738967487493 0.2797089372344611 0.3908604180837625 0.45839956276178245 0.3639484808494708 0.30133853881186856 +P39713 YAL061W BDH2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P39708 YAL062W GDH3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.027337350690644375 0.021503604443052157 0.014165581712251983 1000.0 0.012564824962859263 0.023922094921215352 0.01586397500431191 1000.0 1000.0 +P27616 YAR015W ADE1 0.0029288160884519783 0.0037177257876375544 0.0069209101308387025 0.007995403331446677 0.013005783671841692 0.012670345195014792 0.01344945751462505 0.018679743482449714 0.02190875095526057 0.0004909124612505071 0.0008000054924077844 0.0018591036726976463 0.0027636553374097168 0.0038954812897369026 0.004618213524357634 0.0051682173003896915 0.006068223479344561 0.006881865429009305 0.16761464237584758 0.21518679378345207 0.2686212705484666 0.3456555251615636 0.2995191514811103 0.3644899529789206 0.3842695733095353 0.324855824976712 0.3141149143126702 +P80235 YAR035W YAT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.08568270279120675 0.084665484248101 0.1172609298115251 0.125562625218522 0.1032173422963843 0.10592510771096392 0.11217010642684357 0.032505812404677994 0.023749278849832155 +P35842 YAR071W PHO11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32784 YBL011W SCT1 0.00015741627986827679 0.00029027217680827245 0.0007554181298705151 0.0011280197249780289 0.0016162377464380392 0.0019160998254154715 0.002144296753442312 0.0025177099083953385 0.002855290487873054 0.15741627986827678 0.29027217680827244 0.755418129870515 1.1280197249780288 1.616237746438039 1.9160998254154715 2.144296753442312 2.5177099083953385 2.855290487873054 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32785 YBL013W FMT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32316 YBL015W ACH1 0.0 0.26376276354291617 0.20557295752019336 0.308225587614048 1.0 0.8791692230107985 1.0 1.0 1.0 0.0 0.18830912086723203 0.18409418171971248 0.2974004956004727 0.9156993300773765 1.0109655249085692 1.3671458930747233 1.110038594444829 0.8862238855210716 0.5642143290199332 0.713933681683589 0.8955175035686733 0.9648793207034772 0.9156993300773765 1.1499100496789705 1.3671458930747233 1.110038594444829 0.8862238855210716 +P18239 YBL030C PET9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.729703452407504 0.9592128748409624 1.6695163539672475 1.8338854324866436 1.7552513900752331 2.096341308581434 2.2525943055668787 2.0199890176509756 1.6823809460340828 +P38066 YBL033C RIB1 6.654860918784939e-10 0.00012507370397587172 0.0001677108702279737 0.00015964092353537148 5.280755377221011e-09 0.00026039401332686473 0.00028226890017501706 0.0002904129584980377 9.32912910281518e-09 6.654860918784938e-07 1.0844958534316197e-06 2.5202204775768884e-06 3.7464402209455946e-06 5.280755377221011e-06 6.260498790264349e-06 7.006089689498587e-06 8.226147524609159e-06 9.32912910281518e-06 1000.0 0.008670854216013563 0.015027174291988873 0.02346791873899113 1000.0 0.024042406775326798 0.024820622056324855 0.028325690310629658 1000.0 +P28274 YBL039C URA7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04258734133847046 0.05055578697140595 0.07360716492685493 0.0901420481554678 0.07575312751980283 0.09401422486801755 0.10351422503028056 0.1298956419625446 0.14134837938439634 +P38196 YBL042C FUI1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P07256 YBL045C COR1 0.13608151261417945 0.2486662374639437 0.31127318778069246 0.39162525147638194 0.7332575974400884 0.6476769567178982 0.7012457202330631 0.6897134137972913 0.8585061909343258 0.05303743224983941 0.09379993265771885 0.17984423879717004 0.26120899610617626 0.40642041031304604 0.4382375896175195 0.5546307546513641 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0.0019160833689097624 0.00445271646525804 0.006619197092591769 0.009330019586113791 0.011061026720527263 0.01237833403664398 0.014533927826682742 0.016482671707533748 0.008200912557130693 0.010807995038341305 0.016003101520773298 0.02050734251231546 0.019439646769213673 1000.0 0.019110232790127177 0.018653289694240092 0.016485272456138254 +P07251 YBL099W ATP1 0.16386432284501418 0.22431543814973964 0.3154151352543457 0.362919191725086 0.6034961681008577 0.5400857592618913 0.6547169428109809 0.7086700094404585 0.8113876061706357 0.22288760995833864 0.39513980941475507 0.7694997448269385 1.108656091976822 1.6496896537498058 1.8613331651523082 2.227030114307849 2.370923777608569 2.4947560055397697 1.3601960822744177 1.7615364001428349 2.4396411548432075 3.05482905631686 2.733554479626962 3.4463659395428254 3.401515935644269 3.3455963227237016 3.0746784724921223 +P35172 YBR001C NTH2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P35196 YBR002C RER2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P18900 YBR003W COQ1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.005768349895378213 0.011690528604857852 1000.0 1000.0 1000.0 0.02029774271485361 0.023521018125790133 0.019874170515995028 +P38211 YBR004C GPI18 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38067 YBR006W UGA2 0.0 0.0 0.010550003187666177 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.00039356167691587986 0.0 0.0 0.0 0.0 0.0 0.0 0.04461006965074061 0.041359165445481745 0.037304413080745405 0.03687943799411503 0.02350571204706619 0.02444080888954762 0.020538760744552575 0.020521258115476494 0.01814196549318013 +P00817 YBR011C IPP1 0.0 0.0 0.0 0.0 0.09250461453000462 0.0 0.1262460053665826 0.1365760306768642 0.18578346715455665 0.0 0.0 0.0 0.0 0.06725792185178674 0.0 0.11186220243956925 0.135161304724586 0.16687247104201028 0.5568518221072318 0.6196248357398175 0.7939437259271583 0.9242602455943275 0.727076397145259 0.8183169293804706 0.8860652827370905 0.9896414770200388 0.8982094779358706 +P08431 YBR018C GAL7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P04397 YBR019C GAL10 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P04385 YBR020W GAL1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P05316 YBR021W FUR4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38218 YBR022W POA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P29465 YBR023C CHS3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38071 YBR026C ETR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3467960292494605 0.3377775895682281 0.27618395095248616 0.2675611529087118 0.15395180111582873 0.1351054568019305 0.10066233336165309 0.06240022686143516 0.05872514825775631 +P38221 YBR029C CDS1 0.016197558426942548 0.023474469289009873 0.03378816219099241 0.04038984708970234 0.06471971039119215 0.06599504433704124 0.06842689844208702 0.0766116649798933 0.09455960417578492 0.002647631270940283 0.00431359271385382 0.010097890694111489 0.01502948876183931 0.021156095640414332 0.025081205566703377 0.028068238906824635 0.0329561116452253 0.03737494609053992 0.16345866464270875 0.1837567725492022 0.29885883218600995 0.3721105635398946 0.32688798377709544 0.38004680228127324 0.4101930607096 0.43017093616063057 0.39525277645050677 +P38074 YBR034C HMT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04398915873526187 0.04289540055310864 0.0641078435351584 0.07654108454930118 0.064776224906372 0.10056927132619496 0.10772568181572736 0.09642612236249941 0.08720721033094098 +P38075 YBR035C PDX3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06310434076160634 0.08634359461713037 0.13610134998956086 0.17047607040541582 0.12418577239332321 0.1392801013520479 0.12850581407210887 0.12956788055750693 0.11635114198023216 +P35206 YBR036C CSG2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P14180 YBR038W CHS2 8.408305507645091e-06 1.3702423790236441e-05 3.1842564376174454e-05 4.73356458208168e-05 6.67214612967763e-05 7.910035551636492e-05 8.852077187215247e-05 0.00010393599863616846 0.0001178719864682839 0.00840830550764509 0.01370242379023644 0.031842564376174456 0.0473356458208168 0.06672146129677631 0.07910035551636492 0.08852077187215247 0.10393599863616845 0.1178719864682839 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38077 YBR039W ATP3 0.1638643228450142 0.22431543814973964 0.3154151352543457 0.36291919172508597 0.6034961681008578 0.5400857592618914 0.6547169428109809 0.7086700094404588 0.8113876061706358 0.04354588844343714 0.07719906038542095 0.15033832545357953 0.21659981240044485 0.32230235517312533 0.3636514671270529 0.43509823150758103 0.46321095347979774 0.4874042425738047 0.26574355959487056 0.3441540226664535 0.4766363710871043 0.5968265590223204 0.5340586605336346 0.6733217102854877 0.6645592973957838 0.6536341982999013 0.6007045693908505 +P38225 YBR041W FAT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6827626755670478e-08 2.1033737033082295e-08 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6827626755670478e-05 2.1033737033082294e-05 0.0018815272236147689 0.002054683993909825 0.003230143859815206 1000.0 0.0024384322567712496 0.0023308957137308742 1000.0 1000.0 1000.0 +P38226 YBR042C CST26 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38230 YBR046C ZTA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03965052081592967 0.050367792834387984 0.053559936483036315 0.053526225846546704 0.032928872597554074 0.026902623444781535 0.01837107385575983 0.011803867355490655 1000.0 +Q3E790 YBR058C-A TSC3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.004200540184374305 0.0033836409296565464 0.005102738159995503 0.005109606459924166 0.00520802639272467 0.003907044304837411 0.003938590319015495 0.005241684247644768 0.0033788255229185893 +P38084 YBR068C BAP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38085 YBR069C TAT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38242 YBR070C ALG14 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P09440 YBR084W MIS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.05359859098570196 0.05941703041950538 0.1076367447253071 0.13960648312767823 0.112686970439701 0.14759956003945196 0.1728658601385105 0.1955106762627724 0.216022709493479 +P18238 YBR085W AAC3 6.759755812114858e-05 0.00011831687418795858 0.00023051961307467587 0.00033938958796121986 0.0004816313318763556 0.0005513833050472729 0.0006135490806213671 0.0006911810043100472 0.0007141705003343234 0.06759755812114858 0.11831687418795858 0.23051961307467586 0.3393895879612199 0.4816313318763556 0.551383305047273 0.6135490806213671 0.6911810043100473 0.7141705003343234 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P24031 YBR092C PHO3 0.0 1.1218299913709094e-11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1218299913709094e-08 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P00635 YBR093C PHO5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P22219 YBR097W VPS15 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P16661 YBR110W ALG1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.003101245566786229 1000.0 1000.0 1000.0 1000.0 1000.0 0.0045144213270682096 1000.0 +Q01976 YBR111C YSA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.041422911896241234 0.05096368435865062 0.06675247944673574 0.07668515140600117 0.043207713105250775 0.05391288566559208 0.04799002132503905 0.05138258652987299 1000.0 +P07702 YBR115C LYS2 0.05364256251618565 0.07076884913288067 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1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25578 YCL004W PGS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q3E7B6 YCL005W-A VMA9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.013972109782213048 0.014132652522140136 0.017998248448735914 0.01979012140548737 0.016611128231728122 0.019767409903811522 0.019725173755084025 0.023756539619922315 0.024750861681413352 +P25605 YCL009C ILV6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.21213024570309225 0.2769084293158824 0.47358684506691046 0.46482414473245454 0.36961367680766377 0.3480039120443109 0.37044627472497965 0.3888135318700201 0.36911231415921164 +P04173 YCL018W LEU2 0.0014908509902060495 0.002445223290649162 0.0047913258458380575 0.006030821016167038 0.009509898220138346 0.008983663724855236 0.009032919485584491 0.01209372286266712 0.015069023401472854 0.0006497562823179246 0.0010588620897032846 0.0024606511061854735 0.003657887218974983 0.005155936425430198 0.0061125220632871425 0.00684048974995815 0.008031709600874345 0.00910862047619757 0.4358291248330071 0.4330328824171211 0.5135637160480112 0.6065322133038195 0.5421652583528062 0.6804041480733007 0.7572844815980915 0.6641221807445199 0.6044599064931633 +P25376 YCL025C AGP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P00815 YCL030C HIS4 0.04517351682695564 0.048668355861611896 0.07416144887241817 0.10090084181343967 0.20573024450320573 0.23960564002275003 0.19645836109269454 0.19214637128561074 0.20150193233819774 0.016485708098513928 0.026865598382763436 0.06243198715085367 0.09280843077681915 0.13081714667061514 0.1550877724823162 0.17355787137046605 0.20378166955107493 0.23110520426990813 0.36494187870439804 0.5520136833706806 0.8418388273165618 0.9197983793675085 0.635867356238799 0.6472626122974023 0.8834333667711735 1.0605543481649686 1.1469130920393593 +P25373 YCL035C GRX1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0592818602249814 0.06165955636802447 0.06196803260941631 0.06557222432043107 0.0432149130706567 0.046723836942586375 0.04343716653182985 0.04035361848263234 0.03836172249695555 +P25568 YCL038C ATG22 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P17709 YCL040W GLK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1868671273524054 1.3195779227459719 1.281324087441563 1.27083497100095 0.7716321294726949 0.6735173043221439 0.5225857517093278 0.508389737754593 0.42083612012473576 +P25576 YCL047C POF1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.0014070268062690173 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P16550 YCL050C APA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.11277923220373247 0.09822683856014111 0.10690374033815575 0.11282372257986382 0.09005980336905514 0.10786579555243002 0.09933735955702551 0.10204823416493318 0.10780931578711486 +P25580 YCL052C PBN1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25379 YCL064C CHA1 0.0 0.0 0.0 0.0 0.0 0.0 7.7780656402556e-09 1.1516734305515726e-13 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7780656402556e-06 1.1516734305515727e-10 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25594 YCL069W VBA3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P08679 YCR005C CIT2 0.0 0.0 0.0 0.0 0.9999999999998319 0.0 0.44830067307982413 0.297391366983894 0.3118863783104714 0.0 0.0 0.0 0.0 0.04703085404500077 0.0 0.05466156000295424 0.01879159249213343 0.016999174083234085 0.02593140525564229 0.02023557385133255 0.029851790872075963 0.04008447295306662 0.047030854045008674 0.08546987404566161 0.12193057759077072 0.06318809010064888 0.05450438129206154 +P25613 YCR010C ADY2 0.0 0.0 7.536246695645854e-06 0.0 7.536246695645854e-06 7.536246695775406e-06 7.536246695645854e-06 7.536246695645854e-06 7.536246695645854e-06 0.0 0.0 0.007536246695645853 0.0 0.007536246695645853 0.007536246695775406 0.007536246695645853 0.007536246695645853 0.007536246695645853 0.05729773011394134 0.035788777307877134 1000.0 0.021290529420761976 1000.0 1000.0 1000.0 1000.0 1000.0 +P25371 YCR011C ADP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.005485315697476895 0.004157589322636247 0.004721430093955038 1000.0 1000.0 0.0028021034365364418 1000.0 1000.0 1000.0 +P00560 YCR012W PGK1 0.0023921833681783498 0.0035862718428604085 0.009944052798915335 0.014715417585295256 0.03754397930997877 0.043186546481642434 0.043990446385377656 0.0733959373773161 0.11626134207586385 0.013496425017972562 0.020256709106156595 0.0468679569963732 0.0623679731378027 0.09651350166206635 0.1084080636678422 0.12866286572721566 0.2129846896145471 0.30722086972309814 5.641885650367223 5.648403131091104 4.713164536041623 4.238274094248296 2.570678533173337 2.5102276634674614 2.924791092140019 2.9018593838461224 2.642502350631973 +P25345 YCR024C SLM5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32903 YCR024C-A PMP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.034934841281219896 0.04882773083128789 0.06423243764286164 0.14481581591224216 0.08707458669609906 0.08236970363525002 0.1277136134331476 0.13644250844092926 0.1526067213456798 +P25621 YCR028C FEN2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25358 YCR034W ELO2 1.93294674641148e-06 2.733511377161552e-06 4.01071813984357e-06 4.631499888554696e-06 2.9690330166633058e-06 3.923231952293009e-06 3.252226479952938e-06 0.0 3.2060588740775342e-06 0.00193294674641148 0.002733511377161552 0.00401071813984357 0.004631499888554696 0.002969033016663306 0.0039232319522930085 0.003252226479952938 0.0 0.0032060588740775342 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25332 YCR036W RBK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.02368564745761145 0.02282574289946288 0.02616980724767605 0.0306593871339471 0.02385613760364033 0.025717242807000884 0.024253051891760004 0.030451556581304277 0.03032159820682194 +P25360 YCR037C PHO87 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25628 YCR048W ARE1 0.0 0.0 0.0 4.02793782310674e-06 0.0 0.00011477394722213277 0.00013457080811932795 0.0 0.00017659373042803862 0.0 0.0 0.0 0.00402793782310674 0.0 0.11477394722213277 0.13457080811932795 0.0 0.1765937304280386 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P16120 YCR053W THR4 9.350656893150771e-05 0.00013600178145461476 0.00021662899689393493 0.0002857646548910483 0.0005369754795966943 0.0005639205788477375 0.000615100487686012 0.0007058899949217719 0.0008194895736397583 2.48462033610704e-05 4.049010918100362e-05 9.409349235812772e-05 0.00013987492262528524 0.00020013054210927408 0.00023373835754488453 0.00026551741701078983 0.00030712673880501317 0.0003483069619320424 0.26571612716610216 0.29771749125591856 0.43435317389295497 0.4894759384382736 0.3726995919061071 0.41448807919456243 0.4316651056637229 0.4350915029459364 0.4250291561185325 +P25641 YCR068W ATG15 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P17261 YCR075C ERS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25372 YCR083W TRX3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04476115451944243 0.044122378316410124 0.04137063581074875 0.04087393005701076 0.0241507797963581 0.024069254700027454 0.01979850442445328 0.01636588160441579 0.01380866188451455 +P25346 YCR098C GIT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25377 YCR105W ADH7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25612 YCR107W AAD3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12165 YDL004W ATP16 0.16386432284501418 0.22431543814973962 0.3154151352543457 0.362919191725086 0.6034961681008578 0.5400857592618913 0.6547169428109809 0.7086700094404587 0.8113876061706357 0.021575820829300457 0.038250065726175786 0.07448861166254035 0.1073194028428742 0.15969218028722867 0.1801795572327571 0.21557951443215712 0.22950861483584634 0.2414957412769979 0.13166881267807914 0.17051909597342257 0.23616054950081558 0.29571156689935935 0.2646117551827446 0.33361286451803446 0.32927132373660856 0.32385822989328755 0.29763301711834517 +Q99190 YDL015C TSC13 0.20736501076848346 0.24639150608707436 0.26285260891636236 0.20770077361882194 0.21733446945977522 0.19124814451533173 0.1667547659070003 1.0 5.9066883116934246e-06 0.0034667967318536877 0.004902632897891128 0.007193340719504785 0.008306731009031164 0.005325047872137753 0.007036431673952601 0.005832963661766976 0.026540376474659583 0.005906688311693425 0.016718330247740096 0.01989773501428473 0.027366442163766578 0.039993741305344874 0.024501625928800612 0.036792156555477136 0.0349792920762459 0.026540376474659583 1000.0 +Q00055 YDL022W GPD1 0.0006278534052469211 0.0011057952483168982 0.002677495389789931 0.004242981452726324 0.010627804557201966 0.019429936266812747 0.021653494411692467 0.021580718625909115 0.024893344142562415 0.0001971363520733813 0.00032123604500783483 0.0007494372554221974 0.0011144793224384815 0.0015705066845013754 0.0018616165697100595 0.0020833248422837203 0.002446120197404367 0.002774101856831618 0.313984682452828 0.2905022837607412 0.2799023513840658 0.2626641984782596 0.14777338781951127 0.09581176922797162 0.09621194633411065 0.11334748577221307 0.1114395012957895 +P52290 YDL024C DIA3 4.6498587834649885e-10 7.56916858887946e-10 1.7609187429973894e-09 2.617698278098809e-09 1.3619293532711154e-15 4.3743115962966934e-09 4.895267997036752e-09 5.747742107338667e-09 6.5184131464499925e-09 4.6498587834649885e-07 7.56916858887946e-07 1.7609187429973893e-06 2.6176982780988088e-06 1.3619293532711155e-12 4.3743115962966935e-06 4.895267997036752e-06 5.747742107338667e-06 6.518413146449992e-06 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P12945 YDL040C NAT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.05252546800533536 0.05467535857104325 0.07812280905504831 0.06617087496175256 0.11338050769207873 0.08302380896716412 0.08918101941369615 0.09754792865880937 0.1408888632784373 +P06700 YDL042C SIR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 0.0006502064727468163 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38913 YDL045C FAD1 2.995449362530829e-08 4.8814730352354255e-08 1.1343877678473233e-07 1.6863270485358743e-07 2.3769445404527046e-07 2.817941252158632e-07 3.153542523331067e-07 3.702708239795053e-07 4.1991762359922914e-07 2.995449362530829e-05 4.8814730352354255e-05 0.00011343877678473233 0.00016863270485358744 0.00023769445404527045 0.0002817941252158632 0.0003153542523331067 0.0003702708239795053 0.0004199176235992291 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P33333 YDL052C SLC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.010418289257178415 0.01037911902986619 0.012306544444653813 1000.0 0.017691542777032592 0.019117723416474813 0.024120187828861318 0.025780882632662636 0.022085136022445766 +P41940 YDL055C PSA1 0.0033696289450882246 0.006221085762905492 0.011975837371735343 0.013549675834434201 0.025497824217524008 0.024430580535248384 0.022226138809497982 0.021666689734172663 0.025564371870705625 0.0010634347105666156 0.001733004713515966 0.004027266635386535 0.005986743555782428 0.008438551360699903 0.010004163573478532 0.011195604314020759 0.01314523461672622 0.014907779183313478 0.31559400987362196 0.2785694940663516 0.33628267572265547 0.4418366630268848 0.3309518211714826 0.40949348538994185 0.5037134164408483 0.6067024902282872 0.5831467034946552 +P21954 YDL066W IDP1 0.0 0.0 0.0 0.19978012051193114 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06995961258615371 0.0 0.0 0.0 0.0 0.0 0.19615250383494115 0.214582054350617 0.2797018356170228 0.35018305328320004 0.3086152832928133 0.3696534811510602 0.4054850156503406 0.4292563495917576 0.4030681451418546 +P07255 YDL067C COX9 0.14125460670699755 0.2214194622956823 0.4260599361783745 0.376972581858826 0.741850146779565 0.6079565893741123 0.685892024844011 0.6945609055734133 0.8584255554460701 0.005758498221024097 0.010184255202952245 0.01952644924996482 0.02836056489890611 0.044126781982033944 0.04758130763779606 0.06021860558671378 0.06326570530482468 0.06663713208608561 0.040766799435921194 0.04599530274963927 0.04583028722463561 0.0752324340382054 0.05948206949016872 0.07826431766580691 0.08779604282526685 0.09108733992535038 0.0776271531798217 +P32419 YDL078C MDH3 0.0 0.0 0.0 0.0 1.3002891643378547e-05 0.0 1.4563962014076074e-05 6.259195040730466e-06 6.379397335614681e-06 0.0 0.0 0.0 0.0 2.7414598187891925e-06 0.0 3.1862587533930255e-06 1.1185042842819674e-06 9.913952949839558e-07 0.23710898192324414 0.22760716127914424 0.23046972266403726 0.2633489961566483 0.21083462771030814 0.23893846166142566 0.21877692006567342 0.1786977841405362 0.1554057919310384 +Q07471 YDL080C THI3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q07500 YDL085W NDE2 0.42199538439622997 0.5725892162441016 1.0 9.4455250707491e-05 0.0001461202874726265 0.0001586271856555826 0.0001937221186164545 0.00022337247494377423 0.00025367119460571996 0.020351623265720063 0.030595267119546007 0.04284020094131339 0.094455250707491 0.1461202874726265 0.1586271856555826 0.1937221186164545 0.2233724749437742 0.25367119460571996 0.04822712289812874 0.05343318779252538 0.04284020094131339 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P22007 YDL090C RAM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P52867 YDL093W PMT5 6.295783819464033e-06 1.0259795853941386e-05 2.384236650148879e-05 3.5442931131797524e-05 4.99582104933396e-05 5.922700333866165e-05 6.628061298824635e-05 7.78228833239304e-05 8.825756206174577e-05 0.006295783819464033 0.010259795853941387 0.02384236650148879 0.03544293113179752 0.0499582104933396 0.05922700333866165 0.06628061298824635 0.0778228833239304 0.08825756206174577 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P33775 YDL095W PMT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03238495267868954 0.03820518456555131 0.052380144617467664 0.08219863012658572 0.05573338806244558 0.05899032918632945 0.06159998371355541 0.06717008930160422 0.07076328341201346 +Q12154 YDL100C GET3 0.0 0.0 6.577622129411511e-05 8.870075256979774e-05 0.0 0.00016863739241994898 0.0 0.0 0.0 0.0 0.0 8.515672584577231e-06 1.2658994615426827e-05 0.0 2.115384970047121e-05 0.0 0.0 0.0 0.10972795427737987 0.10695984893622472 0.12946430209938364 0.14271575210667564 0.12018131999880008 0.12543985291110807 0.12304506887070402 0.1393994384501686 0.13627672321020642 +P43123 YDL103C QRI1 0.0015513039502478125 0.0025903228784348274 0.00549538382255337 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0.0205200273565418 +P37303 YEL046C GLY1 0.0 0.0 0.0 0.0 0.004305658632221861 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.00021002222850967896 0.0 0.0 0.0 0.0 0.04327547264148604 0.04074424677526728 0.03823181272616685 0.05351768091022003 0.048778188530311004 0.07067907199862056 0.09515739591518182 0.09526521322832925 0.10644822828560146 +P32614 YEL047C FRD1 0.0 0.0 0.0 0.0 2.7920765493763003e-05 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.964885047611406e-06 0.0 0.0 0.0 0.0 0.07952136387956242 0.07152747066678196 0.06656430989591547 0.08132354293366358 0.07037360949327574 0.07448908365312684 0.08586086051789293 0.06621634231334081 0.05851703619086759 +P32610 YEL051W VMA8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04866982137954036 0.049229048768805524 0.0626942924725446 0.06893602246889373 0.057862460040218444 0.0688569102412449 0.0687097867326003 0.0827524660140809 0.08621604294561286 +P38628 YEL058W PCM1 0.004248368261938139 0.006994617233739058 0.012386892144920317 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0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P0CX08 YEL070W DSF1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P39976 YEL071W DLD3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8353737464914768 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3991588728966602 0.0 0.05372350161815822 0.08026857720692224 0.1695757362275296 0.2809177408982488 0.28215211090820513 0.35949774774635085 0.4718936154318848 0.4778207054903332 0.6291045230938312 +P29952 YER003C PMI40 0.010269207288506535 0.01567685179072398 0.028336961547476388 0.036688938549728274 0.06367759869903018 0.06492729993894568 0.07562069299199027 0.07565761038957004 0.08938420535157597 0.0017995002957446808 0.002932519000472813 0.006814774268144207 0.010130520183451536 0.014279368087529552 0.01692863241182033 0.018944739224645388 0.022243823100177303 0.025226328219976352 0.1752326392085503 0.187060453184101 0.2404906488201489 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6.5472400764098556e-09 0.0 0.0 1.7687062029403113e-06 2.629274746669216e-06 3.706066542591313e-06 4.393656484565664e-06 4.916916754873188e-06 5.77316083355823e-06 6.547240076409855e-06 0.016184908729837716 0.019791409461784915 0.023045825216466188 1000.0 0.013921224130544066 1000.0 1000.0 1000.0 1000.0 +P39518 YER015W FAA2 0.0 0.0 0.09990778361713476 0.0 0.9999999745431881 0.0 0.0 1.0 0.9999999972125007 0.0 0.0 0.015526741305818806 0.0 0.14943152013069588 0.0 0.0 0.05023813842633466 0.039388344049768 0.13282962256048603 0.14482391691058838 0.15541072720940513 0.18841272509973786 0.14943152393474607 0.15035158090377165 0.14476890418208108 0.05023813842633466 0.03938834415956299 +P40015 YER019W ISC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32263 YER023W PRO3 0.00021229141973287384 0.000330260304766133 0.0005581314237375098 0.0006992955956851238 0.001146470903332148 0.0011631867036729325 0.001250661514370634 0.001362958284407571 0.0016263966837053313 1.0159445388316726e-05 1.6556133225405035e-05 3.8474195961310565e-05 5.719391477867194e-05 8.061708053506885e-05 9.55740418012018e-05 0.00010695638339366776 0.00012558203327224843 0.00014242037331399556 0.04785612815204849 0.05013055758284035 0.06893393621106172 0.08178789503548511 0.07031759838017712 0.08216569317669532 0.0855198486278608 0.09213930808369124 0.08756804212704551 +P40017 YER024W YAT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06643975002090821 0.07664859778762277 0.10658648919570152 0.1076279083710945 0.0860791611417163 0.08787325851219975 0.10276914680821454 0.043259724564247246 0.031487750344951444 +P08456 YER026C CHO1 1.9370688286328996e-05 3.1570325245758546e-05 7.40569306746954e-05 0.00011075101633335299 0.0001558646842038246 0.00018478240274339222 0.00020678896842438017 0.00024279971226616974 0.00027535487967863555 0.019370688286328996 0.03157032524575855 0.0740569306746954 0.11075101633335299 0.1558646842038246 0.18478240274339222 0.20678896842438016 0.24279971226616975 0.27535487967863553 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40025 YER037W PHM8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40029 YER042W MXR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1356985658965891 0.1207670934873764 0.13212295160363574 0.14722697942704643 0.10317460118479091 0.12164515595948872 0.1257954838112112 0.10854703108147805 0.09882987782305827 +P39954 YER043C SAH1 0.00011989237870271145 0.00015301211974073244 0.00018422161730307547 0.00019887505562146473 0.00031832907838689003 0.00027866725697899225 0.0002777986312107229 0.000346782413223502 0.0004331901481211742 8.931993271020083e-05 0.000145575388061791 0.00034060937589345175 0.0005097604686698817 0.0007172674279292408 0.0008503427150246389 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1000.0 1000.0 +P00498 YER055C HIS1 0.020845386225328822 0.024156744302843952 0.03219115684985327 0.04046145399775949 0.08101705816264387 0.10085450488664964 0.11006579535048772 0.09462279381564326 0.0927559338936074 0.0018724830899690332 0.0030514539243939797 0.0070911628129382825 0.010541386284270112 0.01485850007503205 0.017615211290819794 0.019713085863840654 0.02314597152878388 0.02624943887234366 0.08982721978515397 0.1263189230361119 0.2202829443506192 0.2605291022130305 0.18339964955532229 0.17465963776846188 0.1791027430553456 0.2446130640982758 0.28299471279597277 +P17064 YER056C FCY2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40039 YER060W FCY21 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12119 YER060W-A FCY22 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P39525 YER061C CEM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.015331213339363907 0.0152881961483598 0.015358664497664432 0.017590054605823587 0.01293022557201637 0.013662464388305953 0.015634954401448256 0.017077736946376328 0.017332016920473845 +P40106 YER062C GPP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.011100996892489544 0.014575801869214516 0.020545885256892802 0.018797963221191472 0.010549398539968658 0.00800298524297581 0.008179458344353551 0.013711275939582128 0.019942789221140494 +P28240 YER065C ICL1 0.0 0.0 0.0 0.0 0.009214840926591104 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.003677402944994127 0.0 0.0 0.0 0.0 0.1962645414295927 0.3363850858313468 0.4200204280314927 0.5204882466210984 0.39907394759059917 0.3223000974536607 0.29064141753968964 0.162126747261529 0.09751027463811479 +Q01217 YER069W ARG5,6 0.15101971520710833 0.11587612808405234 0.3083768732663361 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0.28685815782260426 +P38707 YHR019C DED81 0.06369126857370118 0.08652432264515125 0.13180023062112714 0.1646655983026767 0.29492937364453686 0.2992890518431758 0.31822770804352307 0.33181203703623613 0.3708695376693404 0.008844545091682638 0.014413332742001335 0.033494619837946285 0.04979151310873188 0.07018310318122241 0.08320423901064407 0.09311340527077 0.1093284046055215 0.12398741915562508 0.13886589621696824 0.16658128375199763 0.2541317240500883 0.30237957182294156 0.23796579606143428 0.2780062902342388 0.29259993054418487 0.3294889648430147 0.3343154574916037 +P38708 YHR020W YHR020W 0.14262557572106213 0.19631168965095266 0.30043271382148956 0.3553399291912427 0.6065950697711281 0.5987631648352111 0.585919347505367 0.5675893588842164 0.5903506557767134 0.018637017144096407 0.030371435345934887 0.07057907418458732 0.10491950392232052 0.14788818233787612 0.1753260131333514 0.19620637493368165 0.23037423969785836 0.26126336996446253 0.13067093366582078 0.15471027425792166 0.23492473002298891 0.295265168091631 0.24380050169823372 0.29281362553690793 0.33486925422254366 0.4058818864235488 0.44255624586496506 +P17423 YHR025W THR1 0.01907864341961154 0.031130424927526355 0.04124617874607604 9.421369670929539e-06 1.3479927525723316e-05 1.5743604581684884e-05 0.12346665326321526 2.068672845568374e-05 2.3460450134518614e-05 0.0016735327704940624 0.002727238588953287 0.006337730584556218 0.009421369670929538 0.013479927525723316 0.015743604581684886 0.017884104546963316 0.02068672845568374 0.023460450134518612 0.08771759782321763 0.08760685391550148 0.1536561877300975 1000.0 1000.0 1000.0 0.14484967458246942 1000.0 1000.0 +P23968 YHR026W VMA16 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03767018167747119 0.03810302068849523 0.04852504736280118 0.05335611302689329 0.044785234879385356 0.053294880585434336 0.053181007775907244 0.06404996650182133 0.06673075653898294 +P07275 YHR037W PUT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.13000458887076957 0.13517794925253457 0.15853589386265204 0.20085831858633652 0.16123570278024743 0.21372629025735673 0.21832528703704573 0.22130003669737264 0.19563575739985464 +P48836 YHR039C-A VMA10 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06358218529815338 0.06431275916261814 0.08190373434987937 0.09005792152295465 0.07559143534540971 0.08995456942148522 0.08976236747943558 0.10810770368264135 0.11263251565056959 +P16603 YHR042W NCP1 0.060191368828090015 0.07313156881034223 0.0731166661432254 0.07968866031067488 0.17929537689541847 0.26312161595415995 0.2836614680853368 0.36912989796581724 0.4073904667293477 0.003216899009683166 0.005242353941705899 0.012061896726809816 0.01793064354498868 0.025273949865222523 0.029963049081770502 0.03353148307673047 0.039370738704868236 0.04464966172222507 0.0534445232317413 0.07168387096004056 0.16496781599946359 0.2250087211290053 0.14096264110571358 0.11387528528629343 0.1182095097478761 0.10665822227305496 0.10959918154365733 +P38773 YHR043C DOG2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38774 YHR044C DOG1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38710 YHR046C INM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P00427 YHR051W COX6 0.14125460670699755 0.2214194622956823 0.4260599361783745 0.376972581858826 0.7418501467795651 0.6079565893741125 0.685892024844011 0.6945609055734133 0.8584255554460701 0.01434207613801521 0.025364836095016205 0.04863244045567858 0.0706346282459902 0.10990186028040108 0.11850567816381723 0.14998004568214712 0.15756913132217 0.1659659837192154 0.1015335108168527 0.11455558527707084 0.11414459874330472 0.18737338375564527 0.14814563393630703 0.19492457230510174 0.2186642215533215 0.22686150351650528 0.19333765481035015 +P38787 YHR063C PAN5 0.00017362328665817251 0.00024203115324184817 0.00024356653923026885 0.00028738592361225837 0.0003999776640483218 0.00044018710996573284 0.000470248238662491 0.0007747100814229408 0.0007460188905341912 2.4407970785442998e-06 3.9775952391011595e-06 9.243388936238184e-06 1.374078355332788e-05 1.9368176817896924e-05 2.2961572516999387e-05 2.5696169243485467e-05 3.0170963887640993e-05 3.421635904561234e-05 0.0140580052683239 0.016434228345499687 0.03795015918627248 0.04781300134890034 0.04842314598736451 0.05216320968323419 0.054643839425262054 0.03894484480210298 0.04586527161679715 +P38790 YHR067W HTD2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38791 YHR068W DYS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04911312439027564 0.04858155718050452 0.07882312420432531 0.10083587848266488 0.08153426277387756 0.10022145258864307 0.1050693014255653 0.1505857147867584 0.17810839132289563 +P38604 YHR072W ERG7 2.45840489921109e-05 4.006289465381035e-05 0.9900990099009901 0.99009900990099 0.9900990099009903 0.9900990099014232 0.9900990099009902 0.00030087738727968517 0.9900990099009901 0.024584048992110898 0.04006289465381035 0.09217891490441289 0.13702880259629105 0.19314750629115363 0.2289823411807444 0.2562528759078666 0.30087738727968516 0.34121974857036935 1000.0 1000.0 0.09310070405345702 0.13839909062225397 0.19507898135406512 0.23127216459245067 0.25881540466694525 1000.0 0.34463194605607306 +P38795 YHR074W QNS1 0.01764642402679416 0.023617249374273543 0.048000491387581515 0.06829665792207223 0.12219231453664402 0.15399808652604052 0.1701614581377016 0.1857271956727099 0.22668571628488884 0.0005739422084778067 0.0009353132286306889 0.0021739700956175507 0.0032317208267289123 0.004555238073206619 0.0054003755920397295 0.006043530559197515 0.007095965960015606 0.008047410084976812 0.032524561781261646 0.03960297043099071 0.04529058000810365 0.047318872182828715 0.03727925189468899 0.03506780969727533 0.03551644788038219 0.038206391553556755 0.03550029625538106 +P38714 YHR091C MSR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32467 YHR092C HXT4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32465 YHR094C HXT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38695 YHR096C HXT5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38812 YHR100C GEP4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0033663831447411424 0.0036604409363646603 0.003229698682716587 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38715 YHR104W GRE3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.20174083066182996 0.18824010967967933 0.16884857411127793 0.15754482203749373 0.08982557820296797 0.07182407852764738 0.07835810060348461 0.07935130584350318 0.07110084376670733 +P38816 YHR106W TRR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.01128605949920913 0.007447814903739045 0.009968880839366498 0.005256925838482485 1000.0 1000.0 1000.0 1000.0 1000.0 +P38818 YHR109W CTM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 0.008404878546264264 1000.0 1000.0 0.00851198164799457 1000.0 1000.0 +P38824 YHR116W COX23 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.004675093849824012 0.0038649483699119496 0.005590987456143619 0.010274750331965399 0.006892669018749786 0.008601863805629582 0.007451645281678703 0.008555043072937996 0.0076743211126070665 +P22140 YHR123W EPT1 1.1663101223497488e-05 1.9009560834307252e-05 4.293907826571514e-05 6.233216274982115e-05 9.437213907317718e-05 0.00011188108902957567 0.00012520551006557352 0.00014700910812449287 0.00016672044172320974 0.011663101223497488 0.019009560834307253 0.04293907826571514 0.062332162749821146 0.09437213907317718 0.11188108902957568 0.1252055100655735 0.14700910812449286 0.16672044172320974 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P18562 YHR128W FUR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.02863736727598239 0.028190600772451516 0.0292023524670244 0.03667398630299714 0.04069343609646376 0.0523218384792815 0.051176742300779315 0.060810018232663604 0.057320223319243226 +P38840 YHR137W ARO9 0.019722493812214394 0.030650237262409664 0.027817422269249752 0.036015887967310235 0.053315120269482784 0.06420164114030773 0.09480797416676563 0.7630751476512605 1.0593071259234113e-05 0.0007558491853858802 0.001231754228036246 0.0028624288594705344 0.004255150969579804 0.005079121260332055 0.00704511549210845 0.007950122759587565 0.00933457685492471 0.010593071259234112 0.03832421967437876 0.04018742881142082 0.10290057906029462 0.11814649616419244 0.09526605650816303 0.10973419630678745 0.0838550009053398 0.012232840872431065 1000.0 +P06773 YHR144C DCD1 4.5830573605406697e-10 1.1203028378985995e-09 2.603431026707541e-09 3.870137076376981e-09 5.455110977722158e-09 6.467202746051007e-09 7.237410947106294e-09 8.49775163974222e-09 9.63715054874136e-09 4.58305736054067e-07 1.1203028378985996e-06 2.603431026707541e-06 3.87013707637698e-06 5.455110977722158e-06 6.467202746051007e-06 7.237410947106294e-06 8.49775163974222e-06 9.63715054874136e-06 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38857 YHR162W MPC2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38858 YHR163W SOL3 0.6180713719147513 0.6531253866706772 1.0 1.0 1.0 1.0 1.0 1.0 1.0 0.04734205868137459 0.04894590724543452 0.09864694281320766 0.3889504592903252 0.10594542231183385 0.11265499416494615 0.12089846874486067 0.08324480563151042 0.08569238693619037 0.07659642693805974 0.07494105763510049 0.09864694281320766 0.3889504592903252 0.10594542231183385 0.11265499416494615 0.12089846874486067 0.08324480563151042 0.08569238693619037 +P00925 YHR174W ENO2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.243258081116102 4.739073601333302 5.287512896741267 5.427550558590363 3.3050631776647044 3.863772640568372 4.320544291920813 5.422548751293538 6.148872832685657 +P38720 YHR183W GND1 0.027123043444719466 0.022015885149723975 0.04259313152366681 0.12589934179630421 0.08493803222861088 0.11107432150144095 0.06566248475307984 0.04591867285882107 0.08312668462958409 0.022126554876528513 0.022876155638615253 0.05203308403714371 0.18663446374645187 0.11103918863630616 0.17770942723396627 0.11806544501040958 0.06466145937468068 0.136596832602257 0.8157843688015878 1.0390749898557707 1.221630863375979 1.4824101626235073 1.3072964574625883 1.599914587204216 1.7980654471786772 1.4081735239492899 1.6432368644429654 +P29704 YHR190W ERG9 0.1929511867782571 0.33406299632837155 0.4199557073313025 0.5694185971549011 0.9910829723434492 0.9900990099014233 0.9900990099009901 0.9900990099009903 0.9900990099009901 0.0087562446104779 0.014269435661519541 0.032831903609144314 0.04880635059745659 0.068794477733586 0.08155798060368023 0.09127108656136207 0.10716525994671801 0.12153423487590335 0.045380620646509585 0.0427148047474651 0.07817944377463423 0.08571260377043782 0.06941343929148448 0.082373560409681 0.09218379742697569 0.10823691254618517 0.12274957722466238 +P38698 YHR201C PPX1 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 0.014844318630602185 0.015447383520548988 0.022819209815183997 0.03662211556062466 0.024323190040446047 0.0281620234530516 0.02984592032827612 0.024891648860254845 0.02489912267726547 0.014844318630602185 0.015447383520548988 0.022819209815183997 0.03662211556062466 0.024323190040446047 0.0281620234530516 0.02984592032827612 0.024891648860254845 0.02489912267726547 +P38891 YHR208W BAT1 0.0005468992115024934 0.0008232090634800974 0.0031056144444371247 0.0018471352627054726 0.004486620506878273 0.004552128533029985 0.005080488711402913 0.0069739066002272926 0.0073553909834212635 9.568953454873114e-05 0.00015593850074608037 0.0007799552182945232 0.0005386966389410049 0.001076459920259488 0.001331445135436013 0.0015014735424174685 0.0025458196000566788 0.0028871691943705346 0.17496740265147534 0.18942758002062557 0.25114360853505296 0.2916389772950269 0.23992667055508862 0.29248847561643376 0.2955372263789275 0.36504928241707535 0.39252423166601075 +P38693 YHR215W PHO12 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38697 YHR216W IMD2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04165347378689999 0.047850781143156565 0.04597122648792904 0.012572586842144665 1000.0 1000.0 1000.0 0.021938584036295953 0.0330131615952147 0.04165347378689999 0.047850781143156565 0.04597122648792904 +P40559 YIL002C INP51 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40556 YIL006W YIA6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P39002 YIL009W FAA3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.026887631570380915 0.021566081845321803 0.0390026884208477 0.05568254938085614 0.04863644908333996 0.05263737477290129 0.04577186594652669 0.045375491433140555 0.04745416131286716 +P40553 YIL010W DOT5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.020241615659471905 0.020102773225183442 0.030113630139252296 0.037191230458453725 0.03374213941600313 0.04270398007807013 0.03422455229672102 0.033103417502937216 0.0324943950642499 +P40550 YIL013C PDR11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40545 YIL020C HIS6 0.061212798189365585 0.10499627169743266 0.21770464493371663 3.259017762084174e-06 0.5390055920661498 5.445990207693291e-06 0.5319309548308168 0.5336743033921281 0.5915768411132186 0.000578904470896531 0.0009433998784980503 0.0021923326721914917 0.003259017762084174 0.004593714181095621 0.005445990207693291 0.0060945776241607 0.007155902487471007 0.008115383045716181 0.009457245674436482 0.008985079786610348 0.01007021541896352 1000.0 0.008522572397601125 1000.0 0.011457459974479414 0.01340874470062888 0.013718223029902252 +P40544 YIL023C YKE4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38626 YIL043C CBR1 0.00038104533146273475 0.0006764482915636937 0.0013373989198178947 0.0017605333390065016 0.002920408730142702 0.003119943170639122 0.0035488061777790274 0.004060996419934369 0.004825240341835886 2.3993837102296205e-05 3.9101067870408624e-05 8.99658908584447e-05 0.00013373902601939949 0.00018851043634642324 0.00022348495137452276 0.0002501007772764098 0.0002936539469340432 0.0003330277720285702 0.06296845839887358 0.05780348381104146 0.06726930127227469 0.07596506300464077 0.06454933324939482 0.07163109683460732 0.07047462294289963 0.07231081157633452 0.06901786199977374 +P40527 YIL048W NEO1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P41277 YIL053W GPP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.09138052631057454 0.088537160160358 0.10679519063851511 0.09850006042997775 0.06285938814604855 0.049629522113348805 0.05676637269008158 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0.08436593826086351 0.10419942099871485 0.16324518880772773 0.16629075291988007 0.17004422153508397 0.1703436685274769 0.21367231858856828 0.0058229621370994855 0.00948927163082879 0.022051773278460085 0.032781120179226735 0.046206282884206105 0.05477897714160257 0.06130285138779736 0.07197828197247975 0.08162930255156128 0.19424320187374988 0.19697104147213465 0.2613824220181722 0.31459983045041146 0.2830483594749518 0.3294168567989792 0.3605112295753561 0.4225474453772813 0.3820303120721064 +P08019 YIL099W SGA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40433 YIL107C PFK26 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.010836173302597795 0.008167072162484442 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P00425 YIL111W COX5B 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.10068456841871848 0.11359776265769733 0.11319021246618678 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6.375555760706568e-07 1.4815922193783063e-06 2.202464717346109e-06 3.1044609585169935e-06 3.680434461921729e-06 4.1187539204068375e-06 4.83600394351305e-06 5.484426944178333e-06 0.011848820989582391 0.01166955207028328 0.014449138824694967 0.030707892300889827 0.018164142555109106 1000.0 0.015535351767064588 0.017710006795140204 1000.0 +P32191 YIL155C GUT2 0.0 0.0 0.0 0.0 1.5930490692812775e-06 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2937384996264543e-06 0.0 0.0 0.0 0.0 1.2145410381265762 1.082903339250649 0.9672891201763257 1.0722377086026795 0.8121146577174421 0.9689137572337856 0.8094147077236274 0.714985533711485 0.6229616890985922 +P27796 YIL160C POT1 0.0 0.0 0.0 0.0 0.5489801737668183 0.0 0.6057968141930302 0.7066826613268252 9.79801604321803e-06 0.0 0.0 0.0 0.0 0.027094003191487304 0.0 0.03148997634094937 0.011054241408291875 0.009798016043218031 0.16710259040072115 0.12438590728338565 0.10867396014323266 0.09207417682766628 0.049353336397528265 0.045320422878560904 0.05198108607239299 0.01564244039543448 1000.0 +P00724 YIL162W SUC2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.48101559537350025 0.26353151261069163 0.15481610410265054 0.16749670833425323 0.12333851189974065 0.12066261254171834 0.14596870845522203 0.10316608980295865 0.10779333179861449 +P40445 YIL166C SOA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P0CW40 YIL172C IMA3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32375 YIR027C DAL1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q04895 YIR028W DAL4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25335 YIR029W DAL2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 0.03060759860392964 1000.0 1000.0 +P21826 YIR031C DAL7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32459 YIR032C DAL3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38998 YIR034C LYS1 5.44889205117464e-06 8.87967593524756e-06 2.063515600861507e-05 3.067524413994612e-05 4.323796748015432e-05 5.1259947444383654e-05 5.736472464986635e-05 6.735436007701986e-05 7.638539412480002e-05 0.00544889205117464 0.00887967593524756 0.02063515600861507 0.03067524413994612 0.04323796748015432 0.051259947444383655 0.057364724649866354 0.06735436007701985 0.07638539412480003 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40580 YIR036C IRC24 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06918156876326627 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0.010699747006986083 0.010542365426304214 0.0735951440135289 0.02364898977427489 0.0822991046665767 0.08368470869562225 0.08772150631087972 0.14314171694911126 0.14241517851503158 0.0007258983332262064 0.0011829454319241847 0.011298836720239402 0.004086351283038533 0.01186167791248424 0.014971824255985469 0.0171671105145952 0.030218942966024925 0.03353251012861005 0.06784256980583303 0.11220872964359803 0.1535269326759161 0.17279179034884698 0.14412888160254195 0.17890752670766819 0.195700133713573 0.2111120615995416 0.23545601303354596 +P32861 YKL035W UGP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.20200585847729177 0.19139430913290614 0.21721563313843453 0.24282122401676193 0.17062642757763408 0.18762977640605577 0.16185964311044676 0.18114323131816504 0.160850386037751 +P35731 YKL055C OAR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P14540 YKL060C FBA1 0.012345246064413366 0.01737464962873662 0.0382402277618238 0.04452284618277148 0.10111680309265327 0.09605859843222177 0.11765186394164745 0.2187340091366516 0.33157512580573956 0.04775540563697068 0.0724812614249055 0.16777942040053387 0.21578533962400517 0.34436706404139444 0.3847300630201662 0.46243326585030176 0.782685059815459 1.10491317984442 3.868323513990644 4.1716675140905215 4.3875110118468585 4.846620513391735 3.405636387909249 4.005160072074432 3.9305222234273973 3.5782504188751245 3.3323162500788954 +P36010 YKL067W YNK1 0.004634891690165836 0.005537428522738906 0.013483705660004374 0.017511921070485256 0.03192281638685289 0.030070350131650766 0.026521539783231886 0.03520151541410491 0.048931781356594706 0.0009807761539088699 0.001594373765260539 0.0037043375850004208 0.0055051070062224206 0.007767028612611636 0.009208052590914322 0.010304680901446529 0.012099163591407803 0.01372144844748419 0.2116071355000267 0.2879267441039464 0.27472696886200193 0.314363397600094 0.24330649647223526 0.30621700614062086 0.38854006915396416 0.3437114410864193 0.2804199656556117 +P36088 YKL069W YKL069W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P31412 YKL080W VMA5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0736682447400325 0.07451470973640979 0.09489614612828913 0.1043438342425822 0.08758252540649493 0.10422408736899264 0.10400139638031357 0.12525685828239436 0.13049944241021055 +P17505 YKL085W MDH1 0.044760725277050516 0.07412381645704405 0.1207383355848965 0.15104428837829237 0.26777612071735474 0.2296665892142959 0.21009761656840462 0.2286406376950665 0.2599432644324745 0.013708994044873099 0.026137951918613532 0.04877485579484212 0.06823328292386391 0.11065240848021442 0.12047245654624078 0.15307544233614886 0.1530218866293518 0.15697270155637827 0.3062728309253269 0.3526255550233426 0.40397157670395706 0.45174354923618676 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0.2717576543477291 0.23636686511333954 0.22820154246944416 +Q01802 YKL106W AAT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32332 YKL120W OAC1 0.3509423722103054 0.4918949310899827 0.0 0.9526526804258505 1.0 0.9999999999999835 1.0 0.0 0.0 0.006168507651262514 0.010052382839094466 0.0 0.03472641344414452 0.03120620726022993 0.03390403874791402 0.03730068234807734 0.0 0.0 0.017576981691928555 0.02043603664876062 0.03473983251590265 0.036452333738903955 0.03120620726022993 0.03390403874791458 0.03730068234807734 0.04604623020824484 0.043980619846926895 +P33401 YKL127W PGM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.015468416544123778 0.01656682891731463 0.02821117372682851 0.03143891136501766 0.024881344316767667 0.030814075023262184 0.0330165026126172 0.036714340001624164 0.036421921593241674 +P36001 YKL132C RMA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P34163 YKL140W TGL1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0045363952655498065 0.0027990192567643084 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P33421 YKL141W SDH3 0.11792986428045373 0.1603256336861015 0.2180249379341801 0.18383926940952833 0.32831421565353547 0.2730289150548842 0.3597841641740048 0.362638529595587 0.43549865776927743 0.005411279515744659 0.010539773675161991 0.019068108605586245 0.026409378098587687 0.04465534164981579 0.04705579774325042 0.061969702896886206 0.05978595447309273 0.06021257613831651 0.045885574012668066 0.065739791154031 0.08745838336779047 0.14365471633678553 0.13601403631251785 0.17234730517019153 0.17224132985162569 0.16486376817092704 0.1382612209340413 +P36062 YKL146W AVT3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q00711 YKL148C SDH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.14602582822800733 0.2092097060429782 0.27832675392135925 0.4571654465115149 0.4328498167569248 0.5484764770163758 0.5481392221383823 0.5246609377775981 0.44000123640460337 +P36060 YKL150W MCR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4965425833692456 0.5355698079189501 0.5206225385564746 0.5360637414894652 0.36685272780734707 0.39572612696072595 0.4722958123723258 0.4472328148320336 0.40447031542608647 +P00950 YKL152C GPM1 0.0026827165206074317 0.0035564432717173212 0.01052042915872005 0.014101384904280772 0.03831208871525833 0.04939154917000798 0.051290244292248884 0.09160242777728365 0.11793408881506957 0.007444797110224582 0.011133171505354127 0.025752549330571542 0.03407804969583849 0.05301455949163552 0.05939287595936908 0.07068096445907118 0.11859406540915648 0.17225487282473312 2.775096456534625 3.1304229126585184 2.447861103577326 2.416645593830531 1.383755395996505 1.2024906478421253 1.3780586432058128 1.2946607233762253 1.4606029058726442 +P36051 YKL165C MCD4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P36029 YKL174C TPO5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32895 YKL181W PRS1 0.0195019903966386 0.02842685823546038 0.04600933357827864 0.05634704601522595 0.09353768763901653 0.08402984796286662 0.08914330577819997 0.1336354582888493 0.13068265811074709 0.001453449320295473 0.002368584077518169 0.005504304815046812 0.008182438453663869 0.014481259748217522 0.013851639062354785 0.015321557612489971 0.01798969165582207 0.020383016281076742 0.07452825535930897 0.08332204909522986 0.11963452601811726 0.14521503845033565 0.1548173801783944 0.16484189128220156 0.17187558256603117 0.13461765227712136 0.15597338297024188 +P07149 YKL182W FAS1 0.0633494107576241 0.07543381306964513 0.14324318593242083 0.18524296975032334 0.46176081190315915 0.5207047091132967 0.6504099152511758 0.7564916931659279 0.895339487256773 0.12241997543440852 0.2047131554835178 0.5050402352147728 0.76742742106064 1.2540554915093045 1.3301879025940868 1.6513649089433342 1.883886009831293 2.061263233152143 1.932456418620678 2.7138115806835064 3.525753996096124 4.1428153634926295 2.715811864460049 2.5545916511092277 2.538960231418995 2.4902930552313203 2.302214146130915 +P08432 YKL184W SPE1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P34230 YKL188C PXA2 0.0 0.0 0.0 0.0 0.00044203406170293384 0.0 0.000528253072933492 0.000189979016776019 0.0001680709001791058 0.0 0.0 0.0 0.0 0.44203406170293386 0.0 0.528253072933492 0.189979016776019 0.1680709001791058 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32463 YKL192C ACP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0694270342333302 0.07723298457941527 0.09590368398127035 0.10855438478785806 0.10116778537142539 0.1207262431402853 0.14214960377800326 0.15777338907047783 0.12627443630921106 +P07236 YKL194C MST1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 0.012259719173346778 +P00937 YKL211C TRP3 0.03851784237348251 0.04704697868041449 0.06039906056686654 0.07352719314181037 0.4484851278073131 0.18781587324759433 0.21114076932917655 0.2256445067333911 0.2658470739043894 0.001998263996969652 0.0032564302172839663 0.00756749976630368 0.0112494862051615 0.04505502313357695 0.020565111968336817 0.021233990362954598 0.024931730109538072 0.02808865282915643 0.05187891828399377 0.06921656413697842 0.12529167995793344 0.1529976288291714 0.1004604619864549 0.10949613370125642 0.1005679311978351 0.11049119019323615 0.10565718259234397 +P32368 YKL212W SAC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.02690452094896879 0.03073166452916774 0.04326755216010724 0.06348022324828206 0.041859778655565276 0.05377955263247022 0.04940063648005167 0.05238601790765618 0.053431007307316425 +P28273 YKL215C OXP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03416020350053437 0.033834191269707256 0.03829282961576942 0.03944018879433377 0.029006550678840178 0.03420272826693192 0.030332656546833262 0.031520101090556744 0.02591109881737706 +P28272 YKL216W URA1 0.056466858757771146 0.0899417466255128 0.1534447817093444 0.18847127302201624 0.28570562615419115 0.2983284029206938 0.2641073482735671 0.25750634102967496 0.26930687648850593 0.0032938635584205725 0.00536777765075945 0.012473983290685288 0.01854323188444174 0.026137417310800274 0.030986716438475007 0.03467706357337212 0.04071581343047643 0.046175087291192136 0.058332686302782176 0.05968060274734347 0.08129297817578149 0.09838757698779704 0.09148373331890318 0.10386780519423881 0.13129912439033314 0.15811577015023623 0.17145899834890735 +P36035 YKL217W JEN1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.00411307443182667 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.210288953180471e-05 0.0 0.06932122077365463 0.0692231952273567 0.059813866107943384 0.07554970012072877 0.0712461712784805 0.08661291722019829 0.053129217168391134 0.012667626223497524 1000.0 +P36007 YKL218C SRY1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.007890263247777031 0.006853411783511593 0.010636018233642306 0.009917482139308712 0.013728495336058223 0.02242053455779415 0.024601813483473515 0.025615500385786756 +P36033 YKL220C FRE2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q02207 YKR009C FOX2 0.0 0.0 0.0 0.0 0.012646314477321115 0.0 0.014885155087983593 0.02983113870268376 0.044377020728631165 0.0 0.0 0.0 0.0 0.004561047738405082 0.0 0.005301072874216056 0.0018608886408825202 0.0016494136580310608 0.620553709584641 0.6233610849512524 0.551036101359946 0.5065099355083169 0.36066221084289013 0.356199133504258 0.35613151780296043 0.06238074447741766 0.03716819270309627 +P36126 YKR031C SPO14 1.2462265937184817e-08 2.0312110640774196e-08 4.588129710876895e-08 6.66032107363647e-08 1.0083859101055132e-07 1.1954726775579743e-07 1.337846884235595e-07 1.5708228587991223e-07 1.7814425529751911e-07 1.2462265937184817e-05 2.0312110640774196e-05 4.5881297108768947e-05 6.66032107363647e-05 0.00010083859101055133 0.00011954726775579745 0.0001337846884235595 0.00015708228587991223 0.0001781442552975191 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P19145 YKR039W GAP1 1.317501556482191e-05 2.1474034488330477e-05 5.0168611796069214e-05 7.595796073636198e-05 3.541693207789587e-05 0.00011063258566353504 0.0001309522667266165 0.00015330285444066765 0.0001765151861850089 0.01317501556482191 0.021474034488330476 0.05016861179606921 0.07595796073636199 0.03541693207789587 0.11063258566353504 0.1309522667266165 0.15330285444066766 0.1765151861850089 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P36136 YKR043C SHB17 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.05749158485901376 0.06116800697308685 0.08271392815754994 0.11506874588389801 0.08620204953363927 0.09223971905985244 0.09571483576990714 0.1056518711641059 0.11076079643230041 +P23500 YKR052C MRS4 0.0 0.0 8.600102882327233e-11 1.278450501822728e-10 1.802026447470523e-10 2.1363580754142956e-10 2.390786546994148e-10 2.8071240459429967e-10 3.1835099667098846e-10 0.0 0.0 8.600102882327232e-08 1.278450501822728e-07 1.802026447470523e-07 2.1363580754142956e-07 2.390786546994148e-07 2.8071240459429967e-07 3.183509966709885e-07 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P23501 YKR053C YSR3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P36143 YKR058W GLG1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P33550 YKR061W KTR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P00431 YKR066C CCP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04841299320215129 0.04745142839265188 0.04997074501408018 0.057680324832370206 0.0445932328806382 0.05075757601069582 0.041466143702493075 0.04162699636941708 0.03349512647378078 +P36148 YKR067W GPT2 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 0.04287716337506211 0.04340867442519825 0.04149073803311035 0.05958095348763036 0.0580777803758247 0.06885300450622554 0.07705301783817357 0.09047122147224633 0.10260181970710754 0.04287716337506211 0.04340867442519825 0.04149073803311035 0.05958095348763036 0.0580777803758247 0.06885300450622554 0.07705301783817357 0.09047122147224633 0.10260181970710754 +P36150 YKR069W MET1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.019452071204712238 0.022425398109346788 0.035686732966246394 0.04390867661244154 0.03976950722673985 0.0493985544334925 0.0538042320839907 0.0548104564517134 0.06651879199663185 +P36024 YKR072C SIS2 0.0018621170606163732 0.006592930348391865 1.1626354253316921e-07 0.0192471344364092 0.020017808570965603 0.016040768027623338 0.014442418127329618 3.794910251439702e-07 4.3037409143664223e-07 3.0700397539656014e-05 5.003027747193051e-05 0.00011626354253316921 0.00017283186763117743 0.00024361333973835027 0.0002888111472289796 0.0003232069629859513 0.0003794910251439702 0.00043037409143664224 0.016486824694841674 0.007588473535767567 1000.0 0.008979615547561035 0.01216983062230368 0.01800482038837706 0.022379006073390276 1000.0 1000.0 +P36156 YKR076W ECM4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.08715067429192332 0.09197273528507506 0.0736833950586263 0.06129536860216115 0.032144172302424175 0.025891950636777475 0.023150133190694474 0.01341152318681812 0.009940930254171709 +Q02046 YKR080W MTD1 0.3055789506942076 0.3978257003779249 0.7511924788825572 0.9145874843943799 1.0 1.0 1.0 1.0 1.0 0.022396475664564815 0.036497960342236256 0.08457790715081484 0.12627677902976384 0.10509997876364317 0.19746541230964113 0.22704106851206177 0.266193736155802 0.3041390685644672 0.0732919450560485 0.09174359602098121 0.11259152551238188 0.13806965564741092 0.10509997876364317 0.19746541230964113 0.22704106851206177 0.266193736155802 0.3041390685644672 +P36165 YKR089C TGL4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32901 YKR093W PTR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P10963 YKR097W PCK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.028148580128779917 0.029550877730517386 0.03995104081325481 0.061887117158221726 0.05153467997754453 0.09176642912882552 0.11583801467357334 0.047475000954417 0.02490033410038403 +P54861 YLL001W DNM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.07712964526264295 0.07664852226615151 0.11798848325658416 0.1424543307752272 0.1328570714815894 0.16113138000542737 0.19320890430778132 0.20397629219154578 0.17421360701917865 +Q07804 YLL012W YEH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P14772 YLL015W BPT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P04802 YLL018C DPS1 0.008865921327325488 0.015758061782649102 0.029909095084508782 0.04007259988421053 0.07722895395850354 0.087667294110627 0.09104037939865306 0.1019885803424994 0.11727817895643027 0.00477084449293759 0.007774709544046443 0.018067364792698836 0.026858087515796804 0.03785753454118069 0.04488127782244992 0.05022639063398185 0.0589729388710341 0.06688017187321768 0.538110402382374 0.49337981099979095 0.6040759421724099 0.6702357120177638 0.49019872212075016 0.5119500753133137 0.5516935558237024 0.5782308045958714 0.5702695289808701 +Q3E731 YLL018C-A COX19 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.002997858713609866 0.002478360760357559 0.0035851666301232755 0.006588584272807238 0.0044198573422575575 0.005515861967982244 0.004778295464432498 0.0054858386259947125 0.004921084187290765 +Q07824 YLL028W TPO1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q07830 YLL031C GPI13 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P21801 YLL041C SDH2 0.11792986428045371 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1000.0 1000.0 1000.0 1000.0 +Q12358 YLL057C JLP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12198 YLL058W YLL058W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12372 YLL061W MMP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12525 YLL062C MHT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.005777910453996572 1000.0 0.005596078317949342 1000.0 1000.0 1000.0 0.015043330111594795 0.013157031730727463 1000.0 +Q07923 YLR011W LOT6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q07938 YLR017W MEU1 0.0048598691413428066 0.007832279776613221 0.07005404290382881 0.011432324682356032 0.9999999999952945 1.0 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TRX1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.09505496609651841 0.08429407130256145 0.12558882392499407 0.17913361837525757 0.11739510185437141 0.156971025397243 0.14792347501775596 0.1600202236290251 0.15025316421596907 +P06169 YLR044C PDC1 0.003843650465441142 0.004702334330479305 0.011990188679554013 0.002311289009528714 0.047034200034212964 0.04708663030917451 0.07943024498579548 0.1288873001431675 0.13486037431186296 0.010454696299869202 0.012472215730575699 0.03196943682284013 0.006216146983421192 0.08100313873133601 0.0876152566775903 0.1775700247921217 0.403517379362656 0.691859723420248 2.7199914232235733 2.6523455913659837 2.6662997286569197 2.6894719603623707 1.7222178472773817 1.8607247131999392 2.2355467344193203 3.130776879602805 5.130192815721621 +Q12209 YLR047C FRE8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32353 YLR056W ERG3 0.0 0.0 0.0 0.0 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0.06064766236859925 0.112498926563984 0.07470974984658932 0.15154880838677975 0.14917389776927872 0.14313322239682758 0.3803444712025472 0.46890183883771985 0.013523439325317735 0.02203819741903631 0.08067104999832368 0.07613195472030702 0.12835569326926316 0.13914116040439128 0.18280699880000495 0.5012410462013899 0.5729200937792038 0.3051862464374828 0.36338082224990653 0.7170828421410924 1.01903640256644 0.8469594359440715 0.9327446858001615 1.2771807672518152 1.3178607398093631 1.2218337535193229 +P0CZ17 YLR155C ASP3-1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P0CX77 YLR157C ASP3-2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P0CX78 YLR158C ASP3-3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P0CX79 YLR160C ASP3-4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q06236 YLR164W SHH4 0.1179298642804537 0.1603256336861015 0.21802493793418012 0.18383926940952833 0.32831421565353547 0.27302891505488414 0.3597841641740047 0.362638529595587 0.4354986577692773 0.0045687402545475115 0.008898724991644834 0.01609919338133419 0.02229742308921904 0.03770247986312161 0.039729183593993196 0.052320985335090796 0.05047724776792929 0.05083744420015919 0.038741164355810744 0.05550406873218713 0.07384106393459633 0.1212875962836228 0.11483657443242852 0.1455127329133138 0.14542325801139613 0.1391943868298311 0.11673387114568867 +P32469 YLR172C DPH5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.026323557832579177 0.022290611098740833 0.032918538531278504 0.03636348052194734 0.03452610506525682 0.051108392534035825 0.04251146273004815 0.045527274512090765 0.04587319822936173 +P41939 YLR174W IDP2 0.02750257061441907 0.04930681968777561 0.09569463066581563 0.10755972487087388 0.24132705103275168 0.23737758036316473 0.30957852993651214 0.5331023091096291 0.8091984892302695 0.013369169937418737 0.022910977971886227 0.04756580487670447 0.059119563957354265 0.10963608070362585 0.11748613640599889 0.15145524154172668 0.14997619892271422 0.15375778168073784 0.486106194393681 0.4646614427165423 0.4970582418862513 0.5496440608074041 0.45430497838697165 0.4949335831389657 0.48923044363828094 0.28132723561674267 0.190012442839576 +P10659 YLR180W SAM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.12275163192991179 0.1383822847388138 0.23717373070634462 0.32761074655893274 0.33555689684743734 0.474930347483564 0.5497612362045478 0.6676908809644044 0.6882181747184569 +Q06321 YLR189C ATG26 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q05779 YLR201C COQ9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.005804575062668627 0.006664012682502435 0.008721052545762383 1000.0 1000.0 1000.0 0.013951619948748857 0.01995772129932691 1000.0 +Q05788 YLR209C PNP1 4.117816647243059e-05 6.320899231782114e-05 0.0009862426556457144 0.00016482177493631566 0.017972331286306376 0.01622903347153094 0.015601779974513074 0.01802639203034241 0.021628010891384525 1.0956919486987556e-06 1.7855720645424973e-06 2.7070898504363004e-05 6.16833985935975e-06 0.00052428582998744 0.0006105367830240887 0.0005513110356963578 0.0006712775317298048 0.0006466056709076194 0.02660856571727976 0.028248703215587777 0.027448517207602528 0.03742430186632253 0.02917183205869948 0.0376200335093951 0.03533641908788449 0.037238596087331065 0.02989667769980611 +Q05789 YLR211C ATG38 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32791 YLR214W FRE1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q05979 YLR231C BNA5 0.016022581112475058 0.033553554620589066 0.07799572802497272 0.10485630369783101 0.9802914069300998 0.21447554527985346 0.2227764985392846 8.394591888749167e-06 9.367544229511045e-06 0.000663780511441009 0.0010817163890151965 0.0025137613812952378 0.003736838434776613 0.029226928922449533 0.007694117379909115 0.007149551294007875 0.008394591888749168 0.009367544229511044 0.04142781408197675 0.03223850352807139 0.03222947518985117 0.03563770896926925 0.02981453138916842 0.035874101030351144 0.03209293323526726 1000.0 1000.0 +Q05998 YLR237W THI7 0.0 7.237588288259444e-10 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.237588288259444e-07 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P22543 YLR240W VPS34 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q01662 YLR244C MAP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03528710519476022 0.03332662884384658 0.05370388982083013 0.06729382493796346 0.05601015072155643 0.06936255005890841 0.07677303273426675 0.10305931255457527 0.12694684183866004 +Q06549 YLR245C CDD1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P27472 YLR258W GSY2 0.1911673909750376 0.35381600160192667 1.0 1.0 1.0 1.0 1.0 1.0 1.0 0.017444560588230486 0.028428172810449674 0.06476771033190444 0.05237430419738356 0.03503381385844018 0.021743788913513928 0.01620189441585112 0.01999996912882455 0.03963421303256199 0.09125280467163134 0.08034733500389789 0.06476771033190444 0.05237430419738356 0.03503381385844018 0.021743788913513928 0.01620189441585112 0.01999996912882455 0.03963421303256199 +Q06147 YLR260W LCB5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q05871 YLR284C ECI1 0.0 0.0 0.0 0.0 0.0 0.0 7.564707688481214e-07 8.882044647423391e-07 1.0072970484046467e-06 0.0 0.0 0.0 0.0 0.0 0.0 0.0007564707688481214 0.0008882044647423391 0.0010072970484046467 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q05874 YLR285W NNT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0156660205960451 1000.0 0.018724682611120466 0.021842467422883278 1000.0 1000.0 0.019654832538088366 0.030787829441016375 0.031174442037956974 +P29029 YLR286C CTS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.010210750391386693 0.0072679533676796556 0.016179021561209376 0.02038233069104012 0.016742998167873197 0.018406156170897144 0.025508726359172975 0.02172317200552515 0.01267302065221869 +Q12349 YLR295C ATP14 0.16386432284501418 0.22431543814973962 0.31541513525434567 0.362919191725086 0.6034961681008578 0.5400857592618913 0.6547169428109809 0.7086700094404587 0.8113876061706357 0.01790970603268842 0.03175070085660467 0.06183167482775382 0.08908393204254562 0.13255764530540345 0.1495638533833368 0.17894872972370832 0.19051102881321016 0.2004613297744669 0.10929594509494138 0.14154487590555312 0.19603268174779803 0.24546492462715327 0.219649522750988 0.2769261192662039 0.27332228329910724 0.2688289701487877 0.24705988636004586 +Q05902 YLR299W ECM38 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0067992127477479 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P23776 YLR300W EXG1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03909201189887076 0.037533637998880605 0.040378159727462046 0.04218755073833768 1000.0 0.030808111768682724 0.02674565092537937 0.03836655986248629 0.04160944620833444 +P06106 YLR303W MET17 0.00021200065931424567 0.0003058130907738191 0.0005492927281764362 0.0006770904053764084 0.0011133258611263168 0.001087833536553886 0.0011445185143030044 0.001475500672656384 0.0018073064493182049 0.000450390869717283 0.0007339703062059401 0.001705646904762644 0.0025355337850750865 0.0035739349569233097 0.004237010404007128 0.004741614989523595 0.005567331584005327 0.006313812747703417 2.1244786274446192 2.4000617643565434 3.105169279092986 3.7447492461003513 3.2101427638693956 3.89490695187558 4.142890595711482 3.77318132561899 3.493493176038443 +P19414 YLR304C ACO1 0.07768276013161562 0.14707134638911817 0.19033518259429746 0.20660063773662118 0.39888199483908526 0.30699879883647857 0.2938344633968036 0.2934180266265955 0.3349550318509556 0.08741824084181568 0.16667406583254574 0.3110229734539072 0.43510366556011576 0.7178163471175192 0.7682175794002206 0.9903345416227348 0.9806633874307114 1.0053903760060392 1.1253235684945477 1.1332871420892763 1.6340803061978182 2.1060131775333386 1.7995706910939828 2.502347182828582 3.3703825282242503 3.3422056535016713 3.001568211858976 +P37297 YLR305C STT4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q06702 YLR307W CDA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q06703 YLR308W CDA2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q06178 YLR328W NMA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.02223292855755912 0.020947646481136506 0.024655380580556444 0.03131212866139115 0.02232211663939469 0.02610580489608447 1000.0 0.02795493589335928 0.029527667278961042 +P38631 YLR342W FKS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.09287974522182663 0.12113855292523384 0.24860725386976126 0.2430260879802682 0.1962246131500867 0.21350425108678056 0.24104319956049083 0.26263646253659984 0.2988351478022243 +Q06137 YLR345W YLR345W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04770911063662912 0.03663894838230386 0.03283259235532187 1000.0 1000.0 1000.0 0.029001135674329822 1000.0 1000.0 +Q06143 YLR348C DIC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.754206856362487e-08 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.754206856362487e-05 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q06144 YLR350W ORM2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.010899303297068936 0.008779663358034604 0.013240271110417395 0.013258092552606236 0.013513466540470994 0.01013775824164671 0.010219611898854801 0.013600799872138084 0.008767168636824463 +P49954 YLR351C NIT3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04793821635210371 0.04517785057284208 0.054538283700410244 0.06995252201274725 0.049469410054849734 0.05546354837203353 0.056623545844611205 0.07456927381189862 0.06443493190947108 +P15019 YLR354C TAL1 0.003299332532103734 0.0035765997934947297 0.007420997852266207 0.024268123978278065 0.017035049885276116 0.026001379314608573 0.016087269008118965 0.011284600029650888 0.02564991914664408 0.0024616821633257806 0.0025365373147818978 0.005763424512401501 0.020804154875220308 0.011340230665640768 0.019570646410511424 0.012939507142133242 0.006910908855235195 0.014947140217440258 0.7461152034154473 0.7092035623877904 0.7766374047179491 0.8572625924377884 0.6656998800715257 0.7526772396845841 0.8043321172538918 0.6124194776134212 0.5827363482896544 +P06168 YLR355C ILV5 0.010907827603451834 0.01509068604791269 0.022711490498370287 0.028435224000181773 0.04881698853686952 0.04895375768911916 0.05232992247661949 0.07249850224206862 0.08764747497283089 0.017143652711445204 0.027937804418651433 0.06492364776834327 0.09651241526443231 0.13603805901582008 0.16127732550767016 0.18048456604549246 0.21191459601647453 0.2403286130104449 1.5716835042405706 1.8513276553464397 2.858625583072234 3.394114822651489 2.7866950234563523 3.294483061583583 3.448974458659503 2.9230203309428795 2.7419912905071406 +Q05911 YLR359W ADE13 0.0006928928087203499 0.0011187145882695052 0.0018946152706020977 0.0022876022041621448 0.0035986878772664285 0.003442981077161252 0.0034927539131181648 0.004255713471889543 0.0049349271895007705 0.0002916062390461214 0.00047521016733419245 0.0011043236274982135 0.00164163512351863 0.0023139495079858878 0.00274325869324921 0.0030699656832923303 0.0036045771215413285 0.0040878874621823585 0.4208533201328304 0.42478231026671065 0.5828748689158754 0.7176226358462939 0.6429981112292431 0.7967684491345025 0.8789527575252534 0.8469971358153704 0.8283582118251879 +Q05919 YLR360W VPS38 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40319 YLR372W ELO3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3227409554176445e-07 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.00023227409554176445 0.0 0.0006476244011881525 1000.0 1000.0 1000.0 1000.0 1000.0 0.0009218728305956767 1000.0 1000.0 +P09201 YLR377C FBP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.01984054920411963 0.026073920932747508 0.038034225500976786 0.029062727337390928 1000.0 0.02712118706000268 1000.0 1000.0 +P11325 YLR382C NAM2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.011075552230339798 0.014237920693940174 0.018809170271629046 0.016364654387027555 0.038033581260783884 0.024460112318059363 0.030660441685924487 1000.0 +Q06708 YLR386W VAC14 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.005486407811549889 0.004566602956036769 0.005521856254102796 1000.0 1000.0 1000.0 0.005528088568804924 0.005422318783779382 1000.0 +P04039 YLR395C COX8 0.14125460670699755 0.2214194622956823 0.42605993617837445 0.37697258185882593 0.7418501467795648 0.6079565893741123 0.685892024844011 0.6945609055734132 0.8584255554460701 0.007366213364162234 0.013027597456943221 0.024978038700191964 0.03627855113522285 0.0564465384337177 0.06086553312219582 0.07703103833991952 0.08092885784145819 0.08524155328030512 0.052148482346079286 0.058836731522481256 0.05862564531234086 0.09623657762146999 0.0760888687274067 0.10011493285212439 0.11230782039992127 0.11651801475155764 0.09929987841055177 +Q06685 YLR410W VIP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.045946893025958925 0.045010707136731824 0.05467340260188508 0.06995514072938812 0.0490373603265656 0.05724222303946567 0.053974370472716915 0.06280795040649757 0.06062273671597157 +P20051 YLR420W URA4 0.013329452653563108 0.023533639950248115 0.03891249339619104 0.052034566220017044 0.09263214929399859 0.09865598956553315 0.10175294354707497 0.1328954091751428 0.1481501310839632 0.000520582877413198 0.0008483572817103963 0.001971466637611088 0.0029306887913631884 0.0041309215365102825 0.00489733521714638 0.005480580848322277 0.00643498279024646 0.007297800707440578 0.039055082826228465 0.03604870659633985 0.050664104649846615 0.05632196065537276 0.0445949011006907 0.04964052602090905 0.053861644265718385 0.04842140770841676 0.049259495445904085 +P50095 YLR432W IMD3 0.0 0.0 0.0 0.0 0.0 0.0 0.019342968589105287 0.01483272343950707 0.03554008202743637 0.0 0.0 0.0 0.0 0.0 0.0 0.012617523649348976 0.010591837708135267 0.023114870471957462 0.31121107765619643 0.2844319935701439 0.36448303689970246 0.43870731749593017 0.4925704534867753 0.6239660423404436 0.6523054406682776 0.7140858353715291 0.6503887766526018 +P07991 YLR438W CAR2 0.0 0.0 0.034240370761652386 0.0 0.036199619019097504 0.0522124693459627 0.08615857633971886 0.25202541962504665 0.16868772835895648 0.0 0.0 0.006593293133268552 0.0 0.004096237431833074 0.005212084540820237 0.006426754086206381 0.006028440815893748 0.005024224110534299 0.24067787854611722 0.20623593810895688 0.19255904613780445 0.1729231124332348 0.11315692106240287 0.09982451713372677 0.07459215738275454 0.023919971345996053 0.02978417078356214 +Q06204 YLR446W YLR446W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32366 YLR447C VMA6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06633626301682848 0.067098481864751 0.08545141439251291 0.0939588021531736 0.078865696631511 0.0938509733304575 0.09365044611484888 0.1127904149882268 0.11751122027981371 +P12684 YLR450W HMG2 0.0 0.0 0.0 0.0 0.0 0.0 1.7862342016042518e-05 4.563666502536484e-05 5.489832064770896e-05 0.0 0.0 0.0 0.0 0.0 0.0 0.017862342016042518 0.04563666502536484 0.05489832064770896 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P50107 YML004C GLO1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03330756902949891 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.000852633685714288 0.0 0.12572872034714874 0.11936768708848809 0.08391473016146818 0.06451159316918206 0.027317675868176624 0.02029805995433057 0.026389024052367576 0.02559879662665118 0.028258701869894626 +P25087 YML008C ERG6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.42191242782886873 0.7201292376689786 1.1901210510195694 1.3258413317279667 0.8881213715086641 0.787441113226347 0.603552286925153 0.39226556921171307 0.3626681000594638 +P49435 YML022W APT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.026143834764294435 0.02790592985987526 0.04280275198595604 0.05767332699634337 0.04030150947174338 0.05029690190995202 0.04999838084405055 0.03227580124675984 0.04572412981839696 +P15274 YML035C AMD1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.043909999479551945 0.03668544501210456 0.04480063408954531 0.055803175794044806 0.041747313529585446 0.057511786531813096 0.058417371382709096 0.060212009497802775 0.058368696721309475 +P32796 YML042W CAT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.20479072218825298 0.20685176802268268 0.180129569161476 0.19499480881874645 0.1409253823654357 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YML070W DAK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.13947537616432623 0.14142371114274868 0.1487784371806749 0.15208018886615543 0.12044369190716163 0.11591161087141037 0.10432082972084501 0.11290338041677848 0.10745237315730097 +P12683 YML075C HMG1 0.0956085198633791 0.10590305296727287 0.20439565075582686 0.2664994971327939 0.6332368623657465 0.9505197387321751 1.0 1.0 1.0 0.009317228158443828 0.015183631073019566 0.03493580843905066 0.05193391572357654 0.07320290423537025 0.08678430653811983 0.07926768720519918 0.06842189855833126 0.07445528132113399 0.09745186068937987 0.14337293069078708 0.17092246488544582 0.19487434791555505 0.11560114166741219 0.09130195092410676 0.07926768720519918 0.06842189855833126 0.07445528132113399 +P81450 YML081C-A ATP18 0.16386432284501415 0.22431543814973964 0.31541513525434567 0.3629191917250861 0.6034961681008579 0.5400857592618913 0.6547169428109809 0.7086700094404588 0.8113876061706358 0.00847820738580267 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0.08380660529925263 0.09840089540413564 0.11159472332723695 +P13298 YML106W URA5 0.00014214864256233652 0.00021232274229676293 0.00033111681704418893 0.0004542104397794613 0.0007914242012777717 0.0008381189293163187 0.0007112191642322155 0.0013871718068302044 0.0014239457077008918 5.614741601655367e-06 9.149949276771704e-06 2.1263234398861475e-05 3.160891568339317e-05 4.4554014376098586e-05 5.2820161734091213e-05 5.911075186187175e-05 6.940444479823979e-05 7.871035911950214e-05 0.03949908701515128 0.04309453230395284 0.06421671538363395 0.069590905261316 0.056295996892899096 0.06302227510501208 0.08311186598252558 0.05003305607604176 0.055276236090902785 +P49017 YML110C COQ5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.006720464852415426 0.007715511045216536 0.010097126228378673 1000.0 1000.0 1000.0 0.01615301214775199 0.023106801631188795 1000.0 +P32340 YML120C NDI1 0.08069241448146607 0.13457532368360142 0.1736033780277172 0.20635380579571636 0.39035373712351196 0.3177036423113776 0.3649645877931928 0.39155373842663843 0.469121468108676 0.02542729331534319 0.04867356385698347 0.08735868982525169 0.13091785621615712 0.1996734517541906 0.21579160929356817 0.27637743440563467 0.27433447162900654 0.28062599744315503 0.3151137994660389 0.36168268093056466 0.5032084675869853 0.6344339311374834 0.5115192523211629 0.6792229630218509 0.7572719207547992 0.7006304491724471 0.5981947459674679 +P25297 YML123C PHO84 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12746 YML125C PGA3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0020529958121435024 1000.0 1000.0 0.00350627295065041 1000.0 1000.0 0.0032007102570470233 1000.0 1000.0 +P54839 YML126C ERG13 0.06719275498514286 0.08681947170088293 0.13048907634038123 0.1484567773297821 0.3021777628503016 0.3343472216706601 0.3913471149500829 0.4436655461630768 0.5588418681974385 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9.697135867587528e-08 1.4701741031199484e-06 3.349919663365321e-07 2.847306489498508e-05 3.315720633578206e-05 2.9940757500693635e-05 3.645593229926894e-05 3.511604582114888e-05 0.023196331874926174 0.026467394829513574 0.03358560499418656 0.044031902175472926 0.03767853740103184 0.04679230758155045 0.052244264349382785 0.042376683031014675 0.03578760394965617 +P23585 YMR011W HXT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P20048 YMR013C SEC59 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P54781 YMR015C ERG5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.024010952091216526 0.03501548906829081 0.07443133702952606 0.08364564740152738 0.05407617482101692 0.040819663493493044 0.03862381964941953 0.04310303805790575 0.05367108400771385 +P50264 YMR020W FMS1 2.1121423756605732e-09 3.442009797365802e-09 5.218400294551373e-08 1.189057930005095e-08 1.0106547919695456e-06 1.176918944102968e-06 1.0627507138721744e-06 1.294007610696762e-06 1.246448182345733e-06 2.112142375660573e-06 3.4420097973658023e-06 5.218400294551373e-05 1.1890579300050949e-05 0.0010106547919695457 0.001176918944102968 0.0010627507138721744 0.001294007610696762 0.001246448182345733 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q04212 YMR041C ARA2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.012974092715929352 0.009474171896976375 0.01062752172373385 1000.0 0.00765657324770841 1000.0 1000.0 1000.0 1000.0 +P37296 YMR054W STV1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1694808080860948 0.17142818136896412 0.21831761550494472 0.24005292115538143 0.2014919349917328 0.2397774320762896 0.23926511026316635 0.2881653232670233 0.3002263869936956 +P04710 YMR056C AAC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38993 YMR058W FET3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q04728 YMR062C ARG7 0.037180086672570806 0.039773328804046826 0.11570284727513112 0.0915304186626054 0.28809071320121105 0.4554460700591103 0.5679083679118277 0.46282309280930795 0.4128404743846575 0.003336200642034177 0.005436771416648288 0.024327375039127803 0.018781573984784996 0.03373795645846826 0.04062851536643859 0.04652048530710805 0.051930453369586446 0.05567894089485818 0.08973084628378292 0.1366938996590879 0.21025735850112193 0.20519488776749337 0.11710879564140855 0.0892059851590455 0.08191547780526931 0.1122036782010417 0.13486793168196057 +P07246 YMR083W ADH3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.30228429184514854 0.2949972436824783 0.3243770552884558 0.40203939420345486 0.37220094520282543 0.45890640570045427 0.5003072966424263 0.5350774287860459 0.4628997583541894 +Q04299 YMR087W YMR087W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q04301 YMR088C VBA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q03161 YMR099C YMR099C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1390987900753113 0.12691128183541112 0.14764934636117752 0.16753043278999893 0.1485000615905846 0.1425452657610345 0.14574565065947612 0.12026104081972717 0.10847107424117175 +Q03175 YMR101C SRT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P37012 YMR105C PGM2 0.007954794470005966 0.013185652059525781 0.039464167783406015 0.06571435796498004 0.16734255597649356 0.4271035084906289 0.597154957500759 0.685922058982168 0.9947501826423804 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0.0 0.0 0.0 0.0 0.0 0.0 0.10818142206766156 0.09561844373384029 0.09283121230845504 0.08747289540375644 0.0599212971381008 0.04401031706794266 0.04034157171244727 0.027686222091506715 0.026462560689536615 +Q12676 YMR113W FOL3 0.00034102350473768094 0.0006045108711866187 9.406441913387406e-09 1.3983170374863038e-08 1.9709830610614767e-08 2.3366613652732452e-08 2.6149448546422455e-08 3.0703178372440504e-08 3.481993412425101e-08 2.483852632378974e-06 4.047759845357209e-06 9.406441913387405e-06 1.3983170374863038e-05 1.9709830610614767e-05 2.3366613652732452e-05 2.6149448546422454e-05 3.07031783724405e-05 3.481993412425101e-05 0.007283523270015013 0.006695925645492031 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38009 YMR120C ADE17 0.051962546415096615 0.059007399510893406 0.09692261921862266 0.10720124224368376 0.18724036777116926 0.1752452074999319 0.16089062137415608 0.1798478477590345 0.20680756208640774 0.021169133714616904 0.03449784753492057 0.08016829341921909 0.11917438239338589 0.16798099623541046 0.19914666531530892 0.22286393549560732 0.2616740139723006 0.29675989299929384 0.4073921540624626 0.5846359578776539 0.8271370921001234 1.1116884459462277 0.8971409223074368 1.1363886531127325 1.3851891029579058 1.4549743977081073 1.4349566814936026 +P40215 YMR145C NDE1 0.0 0.0 0.10097963306755224 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.024332399026947546 0.0 0.0 0.0 0.0 0.0 0.0 0.14568910460843493 0.17959253296463504 0.24096343280104737 0.3082073944513161 0.2734199091101006 0.30729736881757946 0.3273521663339674 0.3266889883656075 0.32895000201850527 +Q12674 YMR162C DNF3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32567 YMR165C PAH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P54114 YMR169C ALD3 2.555992102093801e-06 4.284017437945042e-06 0.00010908476855619254 3.168788282707072e-05 0.006147026881548796 0.011678278940457407 0.006646052740589756 0.008876981908643814 0.005674790730117936 3.2884844808226894e-07 5.35901174651499e-07 9.370111067272221e-06 1.8512949669872469e-06 0.00015735315181210273 0.0001832395262491907 0.00016546418791767614 0.00020146955976449722 0.0001940648296737881 0.12865784984737824 0.12509313568727212 0.08589751980310084 0.05842280398126502 0.025598253406768294 0.015690627633014365 0.02489661072159852 0.022695727200741457 0.034197706823588005 +P47771 YMR170C ALD2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.02945514233116735 0.023328965240923663 0.014917058314203424 0.01616546731828657 0.007362879273149884 0.00612546197533957 0.005473212269007063 1000.0 1000.0 +P49095 YMR189W GCV2 0.02658894381618278 0.046751696658939086 0.06225719825790205 0.06867419132564018 0.16065716474193295 0.14990134725449056 0.20144123387956217 0.1769162046369467 0.1853956171454681 0.0080141051762092 0.0156419868415728 0.028192037971524482 0.0390355987159217 0.06606648759800049 0.06961683345461823 0.09187186830814968 0.08840864452990092 0.08887880399647058 0.3014074282759434 0.33457581134827113 0.4528317810695277 0.5684173044109423 0.4112265251545084 0.46441766354793546 0.45607280365984104 0.49972044511878416 0.4794007828498613 +P32352 YMR202W ERG2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P16862 YMR205C PFK2 0.028049154885702057 0.043422643028869536 0.09357551717095408 0.10248871059759251 0.21354619351153828 0.20033057222108253 0.21104568009195643 0.3373617500083368 0.4824536985225728 0.019140665866792948 0.029050943825797017 0.06724704318550766 0.08648811646776161 0.13802447744767896 0.15420222039697712 0.18534615106437474 0.3137050771328945 0.4428561270736031 0.6823972395884849 0.6690275349310842 0.7186392896194561 0.8438794474383137 0.6463448267469176 0.7697388306104438 0.8782276471312565 0.929877430162555 0.9179246183204106 +P32874 YMR207C HFA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P07277 YMR208W ERG12 0.11482061164503708 0.14643945091115537 0.2869976691619566 0.37845238327644887 0.6588751928319828 0.8125783995250747 0.8918843171032704 0.9900990099009894 0.9900990099009901 0.0028499229161444324 0.004644318826309443 0.01068604947430115 0.01588537427964572 0.02239106210140853 0.026545296493630122 0.02970669499335065 0.03487989253836684 0.039556672137144096 0.024820656111420526 0.03171494291608035 0.03723392425278154 0.04197456531286236 0.03398376861810062 0.032667981956134906 0.033307789388913475 0.03522869146375053 0.03995223885851554 +Q03649 YMR210W MGL2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38625 YMR217W GUA1 9.09888516081574e-05 0.0001387058550810572 0.00021012877198029695 0.00024453848178502245 0.00039272593176848894 0.0003518821857541686 0.00038116638513875385 0.0003748203022089683 0.0004135670938127486 1.2705337678660636e-05 2.070499473559513e-05 4.811558435715023e-05 7.152634545023754e-05 0.00010081920732048292 0.00011952428779184437 0.00013375897167256618 0.00015705209075011063 0.00017811001153233516 0.13963620217316347 0.14927268011502112 0.22898141888756607 0.29249525444063834 0.2567164507484462 0.3396713236155304 0.35092016738011844 0.4190063607134909 0.4306677542700685 +P24521 YMR220W ERG8 0.814489919310798 1.0000000000000002 0.9900990099009901 0.9900990099009902 0.9900990099009903 0.9900990099014233 0.99009900990099 0.9900990099009895 0.9900990099009901 0.024872523918580025 0.04053300194138965 0.09326182811437655 0.13863861000865757 0.1954165933839138 0.23167241409351602 0.25926332167737465 0.304412079542036 0.3452283808439268 0.030537546664330194 0.040533001941389646 0.09419444639552033 0.14002499610874414 0.1973707593177529 0.2339891382343488 0.2618559548941484 0.3074562003374565 0.3486806646523661 +Q05016 YMR226C YMR226C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.145943656408976 0.14428413116509506 0.17121327210312556 0.20230111933862022 0.15570317457341523 0.1826831133632733 0.190277209020055 0.2263377585085974 0.21291543921844175 +Q04013 YMR241W YHM2 0.18571284010784248 0.24206603477082994 0.3447320249529288 0.3190554440339976 0.6899281422365839 0.5584054373782139 0.7433651280855653 0.9720775404887744 0.9999999999999725 0.013429403901743006 0.023283160132114573 0.04951447535414664 0.06290178806143483 0.1121029851337153 0.11565026714336842 0.15432177907481076 0.1756267161634465 0.1785827143159623 0.07231273774039867 0.0961851593684233 0.14363178286353742 0.19715002278642266 0.16248501586020817 0.2071080605632378 0.20759889486912747 0.18067150906000656 0.1785827143159672 +P20107 YMR243C ZRC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P47912 YMR246W FAA4 0.003392264845696596 0.005776254555506127 0.01430412619085741 0.017973110684042188 0.0385066076849207 0.040277006689475335 0.04684654617284622 1.0 0.5367912018154045 0.0005030661250785048 0.0008198114630908966 0.001959067722850836 0.002832075963404633 0.004560378607144317 0.004732547991479267 0.005296168372354258 0.0815712382012496 0.042200830112333915 0.1482980097254762 0.14192786263365484 0.1369582242711889 0.15757294400457636 0.11843106628502552 0.11749999268728963 0.11305355047549032 0.0815712382012496 0.07861684388569064 +Q04792 YMR250W GAD1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.020170373839459795 0.0 0.0 0.0 0.0 0.0 0.0 0.028186380025094333 0.02478916088099388 0.020170373839459795 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P10174 YMR256C COX7 0.14125460670699755 0.22141946229568232 0.42605993617837457 0.37697258185882604 0.7418501467795651 0.6079565893741123 0.6858920248440111 0.6945609055734133 0.85842555544607 0.00573286078818599 0.01013891383984848 0.019439515467579514 0.028234300715096534 0.04393032496042788 0.047369470708775285 0.059950506093221306 0.06298403980655533 0.06634045664523129 0.04058530140597526 0.04579052687929045 0.045626246020562124 0.07489749141933646 0.05921724913196173 0.07791587678577819 0.08740516571373685 0.09068180961690778 0.07728154902233579 +P38426 YMR261C TPS3 0.057115667610749425 0.07916943591517869 0.14159629944202365 0.23070939053790676 0.49933969748002116 0.8589802476900724 0.99009900990099 0.99009900990099 0.9900990099009901 0.007613702004021786 0.012407514376924392 0.02883337147819362 0.042862322393011534 0.06041613534672843 0.07162519663042718 0.0801553627645627 0.09411381643860263 0.10673282253786094 0.13330321298019554 0.1567210152945598 0.20363082645390315 0.1857849058205935 0.1209920534089836 0.08338398563068028 0.08095691639220834 0.09505495460298867 0.10780015076323955 +P28239 YMR267W PPA2 9.921071782592627e-06 1.615765028249719e-05 4.087705060042932e-05 5.5808988722671476e-05 1.0 9.477793895862802e-05 1.0 1.0 1.0 0.009921071782592626 0.01615765028249719 0.040877050600429315 0.055808988722671475 0.014510613234673396 0.09477793895862802 0.018418532539825172 0.020220466728691353 0.01643054118284522 1000.0 1000.0 1000.0 1000.0 0.014510613234673396 1000.0 0.018418532539825172 0.020220466728691353 0.01643054118284522 +P30402 YMR271C URA10 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q03529 YMR272C SCS7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 0.004305395991151868 1000.0 1000.0 +Q03262 YMR278W PRM15 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03918214915333618 0.03629168864735148 1000.0 1000.0 1000.0 1000.0 0.03240413512196635 1000.0 1000.0 +P23797 YMR281W GPI12 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q03266 YMR289W ABZ2 1.0671221481119617e-08 1.7390138709967902e-08 4.041231097953816e-08 6.007502463440311e-08 8.467811860471537e-08 1.0038852800749282e-07 1.1234424837062549e-07 1.3190815441930153e-07 1.4959471594818222e-07 1.0671221481119616e-05 1.73901387099679e-05 4.041231097953816e-05 6.007502463440311e-05 8.467811860471537e-05 0.00010038852800749282 0.00011234424837062549 0.00013190815441930154 0.00014959471594818221 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q03557 YMR293C HER2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P25045 YMR296C LCB1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.027278735071445074 0.021973708248370895 0.033137700461304966 0.033182303899415656 0.0338214529504357 0.0253727429868484 0.025577606010543576 0.034040030482643084 0.02194243650738038 +Q03579 YMR298W LIP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.00767123775084894 0.006486463346616994 1000.0 0.007329237055502963 0.004444670326828796 0.0051609291777212785 0.004860815328104653 1000.0 1000.0 +P04046 YMR300C ADE4 0.007590533170653425 0.00984937995799094 0.0141950008022948 0.016857881860277542 0.027372218034646515 0.024840148233892693 0.024906343800395414 0.028652367088860636 0.03194211773180469 0.0007834801320126443 0.0012767824373532215 0.0029671030470051984 0.004410754651784371 0.006217132790426088 0.0073706031681164234 0.008248401380069336 0.009684798454163437 0.010983359445395547 0.10321806313181542 0.12963074252378193 0.20902450717195656 0.26164346673810146 0.2271329558516859 0.2967213842170127 0.33117672534249626 0.3380104137339724 0.34385194925443036 +P40416 YMR301C ATM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P00331 YMR303C ADH2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.300111368985714 3.1291855127019623 3.7102521226262146 4.443950126775116 3.0592116491514494 2.561801648374545 1.3412921011504484 0.4970237197901858 0.5604485828174862 +Q04952 YMR306W FKS3 0.0002212300459514496 0.00036052303784680676 0.0008378063777235451 0.001245443221652605 0.0017555013831517805 0.002081201173024748 0.0023290607615444278 0.0027346491791220852 0.003101317496023098 0.2212300459514496 0.3605230378468068 0.8378063777235452 1.245443221652605 1.7555013831517805 2.081201173024748 2.3290607615444276 2.7346491791220853 3.101317496023098 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40308 YMR313C TGL3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q04894 YMR318C ADH6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.10730160469614437 0.15125256358645062 0.2689137840093254 0.36106995653005947 0.3038592172551782 0.3931529869612912 0.42507075151909834 0.3279756846523498 0.3332408450288022 +P40988 YMR319C FET4 6.507534645838445e-09 1.0604871274699688e-08 2.545494164073707e-08 3.7840108844909874e-08 5.3337127105407513e-08 6.323281346452046e-08 7.076349302082653e-08 8.308642320387283e-08 9.42268499855157e-08 6.507534645838445e-06 1.0604871274699688e-05 2.545494164073707e-05 3.7840108844909875e-05 5.333712710540751e-05 6.323281346452046e-05 7.076349302082653e-05 8.308642320387284e-05 9.422684998551569e-05 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q04902 YMR322C SNO4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P42222 YMR323W ERR3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.97670777975741e-05 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.08976707779757409 0.08704345473645306 0.07228897137309419 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38921 YNL003C PET8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P53982 YNL009W IDP3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.004889689036622031 0.004281415880927767 0.0071780818904232865 0.005083410467896381 1000.0 1000.0 1000.0 1000.0 1000.0 +P53966 YNL029C KTR5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P53615 YNL036W NCE103 2.2485424097243217e-05 2.0750327044478477e-05 4.238311928742282e-05 6.011635780870127e-05 0.0001342047534061505 0.00013879541829914612 0.00018123046978491117 0.00025681492717207855 0.00039084635654306957 7.779798955390351e-07 1.2678190890265753e-06 3.984173582364998e-06 5.085446695560223e-06 8.21710915019366e-06 7.706771467804773e-06 8.919790376769533e-06 1.0725734110362885e-05 1.3184646595033364e-05 0.034599298290950084 0.061098752145399726 0.09400378380237108 0.08459339322822636 0.061228152816061705 0.055526122996325054 0.049217939937780675 0.041764449708860264 0.03373357938308035 +P28834 YNL037C IDH1 0.0 0.0886986998487804 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.02613774059583721 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.23048569195749005 0.2946800870858154 0.4665440913874601 0.596477031122668 0.6155791823284131 0.8351815980707896 1.278452373463489 1.2873009484909197 1.1619109411973958 +P53961 YNL038W GPI15 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q10740 YNL045W LAP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04634926735745751 0.04391475070963868 0.0470645247438199 0.048620264090145505 0.03309622792805642 0.035309191483747795 0.035867974232671754 0.03787618565320239 0.03553897232976852 +P53954 YNL048W ALG11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 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1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P50944 YNL101W AVT4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P06208 YNL104C LEU4 1.348795649863451e-05 2.1980373553330314e-05 0.0 7.593219954786836e-05 6.823497510410092e-05 7.413400867976356e-05 8.156105322772508e-05 0.0 0.0 0.01348795649863451 0.021980373553330313 0.0 0.07593219954786835 0.06823497510410093 0.07413400867976357 0.08156105322772508 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P50942 YNL106C INP52 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P30952 YNL117W MLS1 0.0 0.0 4.460706742708785e-05 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7648613832698874e-05 0.0 0.0 0.0 0.0 0.0 0.0 0.19663725149670583 0.3113277759837373 0.3956461352575191 0.4740985629047614 0.43016530570281464 0.5567331051815028 0.6253540253016772 0.37661277523791137 0.1676384109528446 +P53915 YNL129W NRK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P17898 YNL130C CPT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P53909 YNL141W AAH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.005361174159883734 0.008930442941933545 0.015486278215839134 0.024234598017614437 0.02576142421806239 0.032958487634999103 0.04433894130520559 0.055240462355930754 0.06443813210756594 +P41948 YNL142W MEP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P39006 YNL169C PSD1 5.1042391765983253e-08 8.31904188888467e-08 1.9538341109518753e-07 2.9251129114176075e-07 4.115473924599781e-07 4.879021595558248e-07 5.460086175344234e-07 0.01701272514913937 7.270510527239294e-07 5.104239176598325e-05 8.31904188888467e-05 0.00019538341109518752 0.00029251129114176073 0.0004115473924599781 0.00048790215955582484 0.0005460086175344234 0.00064109191240849 0.0007270510527239294 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 0.0376830817396072 1000.0 +P53871 YNL191W DUG3 1.5058258868544613e-11 2.4539384822813445e-11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5058258868544614e-08 2.4539384822813445e-08 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P08004 YNL192W CHS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32573 YNL202W SPS19 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06822983296714771 0.06376772004264229 0.07444140151014693 0.07184094666874705 0.053788880137643075 0.0599890339332752 0.05794680584568592 0.012550324001442686 1000.0 +P53868 YNL219C ALG9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.008134533964422512 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P80210 YNL220W ADE12 0.05070332680538755 0.06235450456175496 0.0995668454170675 0.11599849460159838 0.18223405055376196 0.16888607648713327 0.17299956614999268 0.18818326312776065 0.22710672888862743 0.009083381318580332 0.014802547333976583 0.034399101474979786 0.051136072608296626 0.07207831287057394 0.0854510687007326 0.0956278199928649 0.11228068574353516 0.1273355492252501 0.17914763963013106 0.23739339183292466 0.34548750973165987 0.4408339330947835 0.39552604275406633 0.5059687007841808 0.5527633514985492 0.5966560674809108 0.5606859376134783 +P23202 YNL229C URE2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.014866248926068325 1000.0 0.023249664670614182 0.017566713584095804 0.020612528295485974 0.021369498795689876 0.018006856254693587 0.018288190349398176 +P11412 YNL241C ZWF1 0.004425441079174316 0.004789322261044358 0.008510234520772757 0.02855633720631084 0.020658133330115097 0.02958441328342753 0.018379963000852734 0.008622632970661192 0.017329390486388527 0.001367350926192954 0.0014136738762425126 0.0032154795921861454 0.011533418025864602 0.006861869743067216 0.010981879071438464 0.007296070106133713 0.0039958731423998944 0.008441251094712839 0.3089750607295555 0.2951720095640938 0.3778367780978813 0.40388296098827975 0.33216310657962944 0.37120489651860855 0.3969578233533557 0.46341681896886855 0.48710605842387067 +P53852 YNL247W YNL247W 0.003109232854597833 0.004457118555492874 0.006270777637776219 0.007447812440069339 0.012997365966585036 0.012010747488060943 0.012344816429000486 0.01255569777917803 0.014152527605462614 0.0001736399474452522 0.0002829688032441147 0.0006575809120843348 0.0009775285930251237 0.0013778651385238994 0.0016335017278182986 0.0018280427800486272 0.0021463826836982565 0.0024341748188158496 0.05584655622961113 0.06348693662083296 0.10486433263443386 0.13125043103475667 0.10601110579376288 0.1360033361322474 0.14808181154919264 0.17094889678355824 0.17199576546851625 +P53848 YNL256W FOL1 0.030683395177408014 0.046507438268645215 1.706074951567936e-06 2.536170099143218e-06 3.5748318667188157e-06 4.238073718305259e-06 0.18680194502198594 0.16822876337896972 0.22430677618045708 0.0004505038991902741 0.0007341545023839475 0.001706074951567936 0.002536170099143218 0.0035748318667188157 0.004238073718305258 0.004742804938695478 0.0055687287538758205 0.006315397253459194 0.014682335399505503 0.015785743737231513 1000.0 1000.0 1000.0 1000.0 0.02538948370230977 0.033102120244034125 0.02815517819389635 +P39104 YNL267W PIK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32487 YNL268W LYP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38971 YNL270C ALP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P53839 YNL274C GOR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3052805856593245 0.2835335023783461 0.20548818784636844 0.1965542128173621 0.12187382296536325 0.11869499101610954 0.09956311483745457 0.07313944877596627 0.05860369327051172 +P53838 YNL275W BOR1 5.7195083760571576e-08 9.32068031653759e-08 2.1659990053772013e-07 3.219871382076622e-07 4.5385358132231337e-07 5.380574546364882e-07 6.021371318126841e-07 7.069947853737319e-07 8.017903408657902e-07 5.7195083760571575e-05 9.32068031653759e-05 0.00021659990053772012 0.0003219871382076622 0.00045385358132231336 0.0005380574546364882 0.0006021371318126841 0.0007069947853737319 0.0008017903408657902 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P08465 YNL277W MET2 0.18816733814122968 0.21325596974984792 0.29410636251514655 0.4073437595629009 0.8445241526748619 0.8826394343898294 0.8985826166969527 0.9900990099009938 0.9900990099009949 0.0031572664218135443 0.0051451749096220545 0.011956684875201086 0.017774240596876333 0.02505349373605786 0.029701691523728084 0.03323899927409243 0.03902732104741758 0.04426019780209004 0.01677903536820958 0.024126756759294536 0.04065428837699937 0.04363449833121031 0.02966581080802238 0.03365099084232615 0.03699047662002824 0.03941759425789161 0.04470279978011073 +P32462 YNL280C ERG24 4.218134103782234e-06 6.87399631727475e-06 1.5816069384368662e-05 2.3511418546934343e-05 3.314027252421502e-05 3.928881783502589e-05 4.396789948661899e-05 5.162457855289038e-05 5.8546525789570037e-05 0.004218134103782234 0.00687399631727475 0.01581606938436866 0.023511418546934344 0.03314027252421502 0.03928881783502589 0.04396789948661899 0.051624578552890384 0.058546525789570036 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P48567 YNL292W PUS4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 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0.004656907022590451 0.005631050348590732 1000.0 1000.0 1000.0 0.005637405906624295 0.005529544535840528 1000.0 +P42884 YNL331C AAD14 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P53824 YNL333W SNZ2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P53823 YNL334C SNO2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P0CH64 YNL335W DDI3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P00890 YNR001C CIT1 0.027641221530855072 0.05135025093474778 0.07848168587189816 0.09475017659895266 0.1539429834756185 0.11944326008931613 0.12291272678728064 0.13443469211383813 0.16831668662296903 0.027649460180598145 0.05271723500721556 0.09837325982487052 0.13761866355908295 0.22316865346297293 0.24297905296558608 0.30873551579691966 0.30862750011191153 0.3165958382443936 1.000298056644634 1.0266207866092971 1.2534549778331776 1.4524370138282587 1.4496838272484072 2.034263404932966 2.5118270814318024 2.2957429757087437 1.8809533659224842 +P40345 YNR008W LRO1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P27515 YNR012W URK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P27514 YNR013C PHO91 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q00955 YNR016C ACC1 0.12170395380336928 0.18780259797735915 0.49363413270755013 0.7216848098616734 0.9999999999999775 0.882125059131189 0.9999999999999999 0.9999999610974148 0.9970366582804915 0.2733502484969521 0.4454596642172555 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1000.0 1000.0 1000.0 +P28241 YOR136W IDH2 0.0 0.08869869984878041 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.02641358136349239 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.23291808851334295 0.2977899496669519 0.4714676952407252 0.6027718629789367 0.6220756059034892 0.8439955631607952 1.2919443309191736 1.3008862880704064 1.1741729959374252 +P53598 YOR142W LSC1 0.054077456405784464 0.07243273967375773 0.10895108014652813 0.15586605148639807 0.21475051948120777 0.1833247943063487 0.26130216914469034 0.3420858677672307 0.4176706412745061 0.01097144960587021 0.01694972423100929 0.03423085094883581 0.05984979912013668 0.06873671107555598 0.07133861227563222 0.09336181509610701 0.09471607610343019 0.10066590919516848 0.20288398040660496 0.234006394171366 0.31418551245934223 0.3839822626504373 0.3200770421492319 0.3891378280038888 0.3572944511012075 0.27687807368844275 0.2410174411301457 +P35202 YOR143C THI80 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 0.00816674048892505 +Q04174 YOR149C SMP3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q99312 YOR155C ISN1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03327192648607901 0.03472215019478907 0.050376799205188144 0.05270852963570001 1000.0 0.03485048626960245 0.04153796744378641 0.03572076953278485 0.032758939968069486 +Q12412 YOR161C PNS1 4.4956466693489305e-06 7.32740522549557e-06 1.655125172036255e-05 2.4026489566513126e-05 3.6376584972863354e-05 4.3125566315552556e-05 4.826158356376118e-05 5.666597542447156e-05 6.426388523794029e-05 0.00449564666934893 0.0073274052254955705 0.01655125172036255 0.024026489566513126 0.036376584972863356 0.04312556631555255 0.04826158356376118 0.05666597542447156 0.06426388523794029 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q99321 YOR163W DDP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P13188 YOR168W GLN4 0.40593764613278216 0.7107902565645143 0.9900990099009899 0.9900990099009901 0.99009900990099 0.9900990099009901 0.9900990099009901 0.9900990099009901 0.99009900990099 0.058578616548698746 0.09546144919047203 0.22183939044831283 0.329775915385267 0.464832170205878 0.5510729112359067 0.6167026575543563 0.7240967878936373 0.8211854208771285 0.1443044691882006 0.134303260784509 0.224057784352796 0.3330736745391197 0.46948049190793684 0.5565836403482658 0.6228696841298998 0.7313377557725736 0.8293972750858999 +Q12246 YOR171C LCB4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 0.0075862078573850815 0.011004537701318946 0.011905229511590563 0.012813786032792249 0.012724250729183772 0.015551910597351929 0.01654259936890319 +Q08548 YOR175C ALE1 9.899651164394242e-05 0.00016130271604810318 0.0005132596086133657 0.0007771059414974974 0.0010504397380722333 0.0012453287909934762 0.0013936405859837362 0.0016363326141498808 0.0018557360133501886 0.09899651164394242 0.16130271604810317 0.5132596086133657 0.7771059414974975 1.0504397380722332 1.2453287909934763 1.3936405859837362 1.6363326141498808 1.8557360133501886 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P16622 YOR176W HEM15 0.0 0.0 1.1553321381302392e-05 1.635990383011105e-05 2.7262397963729632e-05 3.739440707352962e-05 2.5614889541973412e-05 3.534672327417131e-05 4.650175633506608e-05 0.0 0.0 8.278759964573813e-07 1.2306811878877453e-06 1.7346937138483516e-06 2.056533037654522e-06 2.301454787217708e-06 2.7022358319574676e-06 3.0645580895757336e-06 0.04456650938676048 0.055784334076474845 0.07165696938000835 0.07522545368650811 0.06362953530926437 0.05499573863039749 0.08984831980034376 0.07644940129236974 0.06590198588402153 +Q08558 YOR180C DCI1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P33330 YOR184W SER1 0.6268361399060791 0.9737620133916133 1.0 0.9999999999999396 1.0 1.0000000000000062 0.9999999999999989 1.0000000000000036 1.0 0.09735837711553112 0.15866201015845763 0.3690300222653129 0.5500270627652666 0.7650894003277434 0.9072488516606113 1.0178318251799063 1.1946192936098763 1.3569997877038276 0.15531710907753124 0.16293715299679623 0.3690300222653129 0.5500270627652998 0.7650894003277434 0.9072488516606056 1.0178318251799074 1.194619293609872 1.3569997877038276 +P32603 YOR190W SPR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q08579 YOR192C THI72 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P06633 YOR202W HIS3 0.00037873377415610827 0.000416079651538339 0.0006467753308557326 0.0007357485603878487 0.001474560972719602 0.0018563641339341087 0.0022419304469538095 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0.024731834923520362 1000.0 1000.0 +Q02979 YPL110C GDE1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.01415046871874987 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P00812 YPL111W CAR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.012849724016139466 0.013688720372292245 0.015215629878418896 0.012572840808020283 0.007340967235467369 0.006880354031846402 0.008731861737183473 0.009019123107632145 0.008660939858825774 +P15496 YPL117C IDI1 0.0608479626901876 0.0906218083295642 0.13186206063921752 0.14941928867272902 0.2667964519730218 0.272513655015185 0.31968101926492987 0.32513927835345263 0.39421737679583746 0.002253147802231003 0.003671796418450523 0.008448386007621123 0.012558969908639715 0.01770236383503986 0.02098669971576239 0.02348609997717657 0.02757602767768753 0.031273487568553485 0.03702914120071842 0.040517801246001475 0.06406987701137488 0.084051865192234 0.06635157141006472 0.07701155274069833 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0.00019564947751396432 0.00017308745125316655 0.0 0.0 0.0 0.0 0.45522781769902965 0.0 0.5440202790207826 0.19564947751396433 0.17308745125316655 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12036 YPL148C PPT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P26637 YPL160W CDC60 0.03504674048770883 0.053148452645807656 0.08273713709945828 0.10483417118299973 0.17535613287596585 0.17306537182179288 0.1730281091192642 0.17352159737098016 0.1679645019839517 0.009000873351386147 0.014668089905962611 0.03408664074737902 0.0506715833115072 0.07142359687164748 0.084674882638966 0.09475919444931528 0.11126079559352321 0.12617890975924653 0.25682483523803945 0.2759833857010629 0.41198719151236146 0.4833498728487518 0.4073059533205339 0.4892653091004049 0.5476520256255012 0.6411927810672087 0.7512236708879261 +P21592 YPL172C COX10 0.0 0.0 1.6848515053310995e-10 2.5046203306633457e-10 3.530361222661986e-10 4.1853523946611176e-10 4.68380479599379e-10 5.49945417999271e-10 6.236834178658397e-10 0.0 0.0 1.6848515053310994e-07 2.504620330663346e-07 3.530361222661986e-07 4.185352394661118e-07 4.6838047959937905e-07 5.499454179992709e-07 6.236834178658397e-07 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32363 YPL175W SPT14 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q06892 YPL188W POS5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.060886450970838044 0.06488257182992248 0.06805716136715068 0.08611611134541902 0.05706600173550914 0.054252086241081694 0.051668248238617036 0.048548757883540884 0.05209959137399513 +Q08929 YPL189W GUP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q08959 YPL206C PGC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12211 YPL212C PUS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.038533689414877344 0.04291062451111862 0.06853546949256828 0.07140305046278775 0.05395363119082382 0.06293520534474814 0.060325908496058546 0.07515197157728701 0.08022368073601514 +P41835 YPL214C THI6 0.0 0.0 0.0 1.8455677882658884e-09 2.601400648920833e-09 3.0840409093390506e-09 3.45133318299065e-09 4.052356903511449e-09 4.595706630648938e-09 0.0 0.0 0.0 1.8455677882658883e-06 2.601400648920833e-06 3.0840409093390504e-06 3.45133318299065e-06 4.052356903511449e-06 4.595706630648938e-06 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40350 YPL227C ALG5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P19097 YPL231W FAS2 0.0633494107576241 0.07543381306964514 0.1432431859324208 0.18524296975032337 0.4617608119031591 0.5207047091132968 0.6504099152511758 0.7564916931659279 0.895339487256773 0.11078025220154944 0.1852489752016807 0.4570208777651573 0.6944602214614317 1.1348195678945654 1.2037132894523113 1.4943527021662253 1.7047656360615704 1.865277786669071 1.7487179576996623 2.4557816669117263 3.190524385437576 3.748915396883608 2.4575917631844444 2.311700409819806 2.297555229595685 2.2535153412288023 2.0833190239202874 +P32842 YPL234C VMA11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.02840267681178424 0.02872903007036171 0.036587061069217726 0.040229602480048726 0.03376730601168739 0.04018343425978247 0.040097576096571594 0.04829258626710613 0.05031385639735584 +Q12520 YPL244C HUT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12184 YPL252C YAH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q08975 YPL258C THI21 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P08417 YPL262W FUM1 0.009857903852464524 0.016469892844466105 0.018786893021591047 0.021372609970599112 0.03757598294825575 0.03009588439767235 0.03256648348705989 0.03222139856911885 0.036191587468776376 0.0034001846633188457 0.006582566136700309 0.012014669821024167 0.016688843390818803 0.028019227440849784 0.029657299104518583 0.03882220478909558 0.0377321203060504 0.038199249649046405 0.34491964155937505 0.39967267540007434 0.6395240451529783 0.7808519134432594 0.7456685159622795 0.9854270674568484 1.1920907826760405 1.1710267704584698 1.055473172653786 +P53388 YPL265W DIP5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P32383 YPL268W PLC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P21306 YPL271W ATP15 0.16386432284501418 0.22431543814973962 0.31541513525434567 0.362919191725086 0.6034961681008578 0.5400857592618913 0.6547169428109809 0.7086700094404588 0.8113876061706358 0.008547929486014865 0.015153947896098903 0.029510969943625707 0.04251790442829029 0.06326700186115058 0.0713837106004983 0.08540849975417364 0.09092694417380211 0.09567601547772016 0.05216467707921785 0.06755641975022258 0.09356231405898939 0.11715529351365335 0.10483414014084882 0.13217106612485935 0.13045103031468575 0.12830646557993172 0.1179165355128673 +Q08985 YPL273W SAM4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q08986 YPL274W SAM3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q08992 YPL280W HSP32 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P0CX11 YPL281C ERR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P43635 YPR001W CIT3 0.0 0.0 0.0 0.0 8.616111972928582e-05 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.532911408044645e-06 0.0 0.0 0.0 0.0 0.10419445724373293 0.09020807518421785 0.08363572751307867 0.07919297459909531 0.05260970867471128 0.07045052295900622 1000.0 1000.0 1000.0 +Q12428 YPR002W PDH1 0.0 0.0 0.0 0.0 0.030190298961598337 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.015257774239794327 0.0 0.0 0.0 0.0 0.30471470228089903 0.28968655916078784 0.37758374120958776 0.4976069047684469 0.5053866561308987 0.7210995654670044 0.8471017230055674 0.3409235815853671 0.2747101742703806 +P53394 YPR003C YPR003C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12031 YPR006C ICL2 0.0 0.0 0.0 0.0 0.00023888396699867705 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8590522521894927e-05 0.0 0.0 0.0 0.0 0.1760277424608742 0.1731876068641715 0.19693561628850653 0.24284364529062746 0.24526770573187695 0.3214102192377023 0.33974119735837843 0.05754328308719099 0.03676081404570139 +Q12251 YPR011C YPR011C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12233 YPR020W ATP20 0.16386432284501415 0.22431543814973962 0.31541513525434567 0.362919191725086 0.6034961681008578 0.5400857592618914 0.6547169428109808 0.7086700094404587 0.8113876061706357 0.016379622851668107 0.029038137441123227 0.05654919807824229 0.08147320823341818 0.12123282382439964 0.13678613742681872 0.1636605702689719 0.17423506535217217 0.18333528043713807 0.09995844468939252 0.1294522467140184 0.1792849859048201 0.22449407496513643 0.2008841650244561 0.2532674396261764 0.24997149083435483 0.2458620557256856 0.2259527740414887 +Q12482 YPR021C AGC1 3.571414556063735e-05 5.8200829802520125e-05 0.0002741499538059439 0.00020105741204506952 0.00037933032380313257 0.000462670106979423 0.0005259164794751871 0.0007323048309756084 0.0008114781962776321 0.03571414556063735 0.05820082980252012 0.2741499538059439 0.20105741204506952 0.3793303238031326 0.46267010697942296 0.525916479475187 0.7323048309756085 0.8114781962776321 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P48016 YPR026W ATH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P07263 YPR033C HTS1 9.393933009076622e-07 1.5308631570347088e-06 3.5575172228817946e-06 5.288436360665358e-06 7.454259804424691e-06 8.837255497427638e-06 9.889723917888999e-06 1.1611944969553046e-05 1.3168902384946299e-05 0.0009393933009076622 0.0015308631570347087 0.0035575172228817947 0.0052884363606653575 0.0074542598044246905 0.008837255497427638 0.009889723917888999 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0.7674541005253432 0.0404282844433285 0.06588313020394274 0.1531034105307533 0.22759626797725674 0.320805923777153 0.3803253425409422 0.42561999455615285 0.4997385160355884 0.5667446541407346 0.2791464887478622 0.30708698530722 0.4263188383870926 0.5524087331422445 0.46354354118574215 0.556228496551181 0.6139523763657929 0.727244132798626 0.7384736803839896 +P38011 YMR116C YMR116C 0.12020046163497301 0.1667626487120874 0.28841476653757103 0.31488180627019463 0.5619960513375415 0.5092354022774942 0.515318144431575 0.5289053235621795 0.6051821380836763 0.1041915172195519 0.16979358361704755 0.39457713465552524 0.5865596524952552 0.8267789838625554 0.9801720508802291 1.0969051396169494 1.2879229211861276 1.4606107136148292 0.8668146178669649 1.0181751425056398 1.3680892257786832 1.862793088756416 1.4711473183749866 1.92479165135913 2.128597937933852 2.435072713036733 2.413505987205584 +P16521 YLR249W YLR249W 0.36146420369481486 0.4352917278006302 0.5556003569150045 0.5617348863928209 0.9125163555714103 0.877542724220817 0.8226505843810894 0.7928364243384436 0.8205693390400388 0.34709051756991655 0.5656289915954195 1.3144446452416283 1.9539910618750855 2.7542275329390598 3.2652219060281036 3.6540918377499545 4.2904244532948015 4.865694848156051 0.9602348282956559 1.2994250877528406 2.3658095767615057 3.4784933412675048 3.018277443601967 3.7208694413452537 4.441851628293759 5.411487567406866 5.929657149812948 +P05749 YLR061W YLR061W 0.28157638477080543 0.4623242722732994 0.6581441927714389 0.7458242563432125 0.9900990099009901 0.9900990099009901 0.9900990099009901 0.9900990099009901 0.9900990099009901 0.04099107729600127 0.06680027411200207 0.1552347279080048 0.23076458329600716 0.32527178928401007 0.385619764192012 0.4315449526440134 0.5066952610200157 0.5746341761680177 0.14557711339808116 0.14448792355966464 0.2358673518857818 0.30940879347025985 0.32852450717685017 0.3894759618339321 0.4358604021704535 0.5117622136302159 0.5803805179296979 +P33442 YLR441C YLR441C 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0.9680728895034111 1.1318270959063135 1.0990959980887431 +Q01855 YOL040C YOL040C 0.18361140684449745 0.250779196159159 0.42251454154002904 0.5059887124841232 0.8248830349385222 0.7895381157889202 0.7824693680093618 0.7877420039540696 0.894518099963596 0.04790325121526417 0.07806455753598605 0.18141138654669486 0.2696775623970427 0.38012116936556845 0.45064540032137407 0.5043147836273645 0.5921374108553488 0.6715326142584253 0.26089474525857737 0.31128801244917365 0.42936128514172794 0.5329714986586871 0.4608182654573548 0.5707709245564179 0.6445169667285053 0.7516895225633724 0.7507199846327922 +P05759 YLR167W YLR167W 0.1666386891232629 0.2937903454862199 0.5228676043939684 0.6424438773228156 0.9900990099009901 0.9900990099009901 0.9900990099009901 0.99009900990099 0.9900990099009901 0.05153745612560855 0.08398696553802874 0.19517425514235087 0.29013679004046294 0.4089592583300604 0.4848338465149841 0.5425748853223789 0.6370602215526612 0.7224787830941789 0.3092766535596437 0.2858738104515695 0.3732766258651046 0.45161421920544637 0.413048850913361 0.489682184980134 0.5480006341756026 0.6434308237681878 0.7297035709251207 +P46654 YLR048W YLR048W 0.4190404623779174 0.647293414112473 0.9900990099009902 0.9900990099009901 0.9900990099009901 0.9900990099009901 0.9900990099009901 0.9900990099009902 0.9900990099009901 0.08370645609806379 0.13641052104869653 0.31699944948248227 0.47123634544095166 0.6642262303337099 0.7874607351447482 0.8812429683657271 1.0347048045455107 1.1734405049302643 0.1997574545022623 0.21073985626091044 0.32016944397730707 0.47594870889536117 0.670868492637047 0.7953353424961958 0.8900553980493844 1.0450518525909658 1.185174909979567 +P29453 YLL045C YLL045C 0.1355069640643184 0.20288683265382992 0.33333239154456695 0.39751942688397307 0.643839991682261 0.6175692831238268 0.6532609185754995 0.6145813548117735 0.6801098875302033 0.08415549294860059 0.13714228480512686 0.3186999686664596 0.4737642565995292 0.6677894208976917 0.791685007738687 0.8859703285422117 1.0402553989479795 1.1797353363350116 0.6210418300616356 0.6759545851806071 0.9561026073394642 1.191801518514994 1.0371977968514416 1.2819371516247333 1.3562273562517075 1.6926244032681015 1.7346245922393244 diff --git a/literature/xia2022/results/modelGeneration/minimumUsage_mu003.tsv b/literature/xia2022/results/modelGeneration/minimumUsage_mu003.tsv new file mode 100644 index 0000000..42bd02d --- /dev/null +++ b/literature/xia2022/results/modelGeneration/minimumUsage_mu003.tsv @@ -0,0 +1,8 @@ +protein measured_mg_gDW required_mg_gDW fold_change +P21147 0.05213013285796384 0.07417992635810328 1.4229759697758169 +P53045 0.0006047608104348805 0.002058642995266972 3.4040615062120376 +P38972 0.3098256816609233 0.3143379515043612 1.0145638987034529 +P05374 0.014419332901717022 0.15667400101963735 10.865551276715511 +P32476 0.07851684747277426 0.1620777380333681 2.064241538601873 +Q12452 0.01394831829316533 0.030402854056062523 2.1796788270138565 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a/literature/xia2022/results/modelGeneration/minimumUsage_mu010.tsv b/literature/xia2022/results/modelGeneration/minimumUsage_mu010.tsv new file mode 100644 index 0000000..7ee6dea --- /dev/null +++ b/literature/xia2022/results/modelGeneration/minimumUsage_mu010.tsv @@ -0,0 +1,12 @@ +protein measured_mg_gDW required_mg_gDW fold_change +P13663 0.6514635592672777 0.966864958141017 1.4841428110399322 +P21147 0.16307749755435774 0.2809221285228171 1.7226296253974516 +P53045 0.006499327337356519 0.007796157269112884 1.1995329461715998 +P38972 0.5120568880938641 1.1904234141868002 2.3247874247296254 +P05374 0.025698938900190395 0.5933302446021447 23.087733190328294 +P38604 0.006992891449076351 0.09310070405345702 13.313620657697202 +Q12452 0.02870559905610853 0.11513673434194048 4.010950411342817 +P24521 0.04872422386570917 0.09419444639552033 1.9332159431648106 +Q12362 0.002520842809939425 0.019424733753999154 7.705650537752461 +P13188 0.17771523170978407 0.224057784352796 1.2607686026524227 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4.745465016978075 +P24521 0.057791532068223274 0.14002499610874414 2.42293275671328 +Q12362 0.003010155459883546 0.02887588782990583 9.59282276770614 +P13188 0.2185476679895188 0.3330736745391197 1.5240321601376838 +P33330 0.2606100410123289 0.32833347987557654 1.2598650405033467 +P18408 0.024748735382605882 0.04414052934199457 1.7835468624800035 diff --git a/literature/xia2022/results/modelGeneration/minimumUsage_mu021.tsv b/literature/xia2022/results/modelGeneration/minimumUsage_mu021.tsv new file mode 100644 index 0000000..3b6ff20 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/minimumUsage_mu021.tsv @@ -0,0 +1,17 @@ +protein measured_mg_gDW required_mg_gDW fold_change +P13663 0.5242537506363875 2.0259248633908316 3.864397461976338 +P49367 0.254885243301397 0.5841610590033117 2.291859079156467 +P21147 0.14507299725515674 0.5886314526749492 4.05748460300751 +P53045 0.004496135891850007 0.01633571339762773 3.633278395174604 +P38972 0.47790460842377536 2.494359085473325 5.219366043989863 +P05374 0.035561627263871506 1.2432372117947141 34.96007656145052 +P32476 0.37895227982366597 1.286116865690708 3.393875519865361 +P38604 0.005914026427748481 0.19507898135406512 32.985814949821474 +P36148 0.040753336048651154 0.0580777803758247 1.4251049363539638 +Q12452 0.025302058623649218 0.24125227709301467 9.534887286504112 +P24521 0.04111299272847264 0.1973707593177529 4.800690638632701 +Q00955 1.5264387278546077 2.1907756906621003 1.4352201963201043 +P18544 0.17180895020255033 0.24538937487982673 1.4282688683594795 +P13188 0.19692752390721358 0.46948049190793684 2.3840267860633952 +P06780 0.12497255447601098 0.19784657877010323 1.5831202266740954 +P18408 0.022981376713526035 0.06221781849685736 2.707314677986116 diff --git a/literature/xia2022/results/modelGeneration/minimumUsage_mu025.tsv b/literature/xia2022/results/modelGeneration/minimumUsage_mu025.tsv new file mode 100644 index 0000000..ff887d6 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/minimumUsage_mu025.tsv @@ -0,0 +1,20 @@ +protein measured_mg_gDW required_mg_gDW fold_change +P13663 0.5186291607581551 2.4017965708344104 4.631048063944877 +P49367 0.30037636422026925 0.6925409987717208 2.3055775395958684 +P53199 0.10656787497008013 0.11258556480436378 1.0564681414166621 +P21147 0.15811347490321606 0.6978407887021569 4.413544064661896 +P53045 0.0016159152496471158 0.019366493362881886 11.98484472939478 +P38972 0.610695778098701 2.95713982595248 4.842247043460885 +P05374 0.05058065230353151 1.4738961577402914 29.139524514146782 +P32476 0.15206187667968296 1.5247313133509444 10.027045217670027 +P38604 0.004493172392073085 0.23127216459245067 51.47190991390941 +P29704 0.05834452240898612 0.082373560409681 1.411847368160031 +P36148 0.04043749917198467 0.06885300450622554 1.7027018464566002 +Q12452 0.01995669503731559 0.28601203445332896 14.331633264853503 +P24521 0.04326641502728813 0.2339891382343488 5.408100904287352 +Q00955 1.6179006729342105 2.5972323240521518 1.605310120393135 +P22768 0.6625454863796315 0.8162094427722406 1.2319296705684013 +P18544 0.1508869223769125 0.29091669180618895 1.9280444403225674 +P13188 0.235459123896664 0.5565836403482658 2.3638227779720005 +P06780 0.11270140793630938 0.23455323690831373 2.0811917189256954 +P18408 0.029417111118860133 0.07376114771633056 2.5074232278723056 diff --git a/literature/xia2022/results/modelGeneration/minimumUsage_mu028.tsv b/literature/xia2022/results/modelGeneration/minimumUsage_mu028.tsv new file mode 100644 index 0000000..32d0897 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/minimumUsage_mu028.tsv @@ -0,0 +1,27 @@ +protein measured_mg_gDW required_mg_gDW fold_change +Q00764 0.03664188610034028 0.038251095566034524 1.0439172116109847 +P31688 0.0672015897818024 0.0701528962208444 1.0439172116109847 +P38427 0.08028089236111102 0.08380660529925263 1.0439172116109847 +P38426 0.07755108881409735 0.08095691639220834 1.0439172116109847 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a/literature/xia2022/results/modelGeneration/modifiedEnzymes_mu003.tsv b/literature/xia2022/results/modelGeneration/modifiedEnzymes_mu003.tsv new file mode 100644 index 0000000..93113f3 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/modifiedEnzymes_mu003.tsv @@ -0,0 +1 @@ +protein previous_mg_gDW modified_mg_gDW flex_mass_mg_gDW fold_change diff --git a/literature/xia2022/results/modelGeneration/modifiedEnzymes_mu004.tsv b/literature/xia2022/results/modelGeneration/modifiedEnzymes_mu004.tsv new file mode 100644 index 0000000..93113f3 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/modifiedEnzymes_mu004.tsv @@ -0,0 +1 @@ +protein previous_mg_gDW modified_mg_gDW flex_mass_mg_gDW fold_change diff --git a/literature/xia2022/results/modelGeneration/modifiedEnzymes_mu010.tsv b/literature/xia2022/results/modelGeneration/modifiedEnzymes_mu010.tsv new file mode 100644 index 0000000..c6b6528 --- /dev/null +++ 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a/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu003.tsv b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu003.tsv new file mode 100644 index 0000000..0cf96f0 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu003.tsv @@ -0,0 +1 @@ +protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change diff --git a/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu004.tsv b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu004.tsv new file mode 100644 index 0000000..0cf96f0 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu004.tsv @@ -0,0 +1 @@ +protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change diff --git a/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu010.tsv b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu010.tsv new file mode 100644 index 0000000..2c4b9c7 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu010.tsv @@ -0,0 +1,6 @@ +protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change +P32473 0.20809670595319302 0.33316228565359207 0.12506557970039905 1.6009974022776214 +P16387 0.24077060078865592 0.38547310640746035 0.14470250561880443 1.6009974022776214 +P16451 0.1178369548041237 0.18865665853370756 0.07081970372958385 1.6009974022776217 +P12695 0.6730385922181652 1.0775330377738699 0.4044944455557047 1.6009974022776214 +P33330 0.3619717114546589 0.3690300222653129 0.0070583108106540005 1.0194996199628106 diff --git a/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu015.tsv b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu015.tsv new file mode 100644 index 0000000..fbb9819 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu015.tsv @@ -0,0 +1,8 @@ +protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change +P32473 0.45214651693742036 0.5792730757802731 0.12712655884285273 1.281162309297293 +P16387 0.5231394126536894 0.6702264979998301 0.1470870853461408 1.281162309297293 +P16451 0.25603273457476483 0.32801948948350657 0.07198675490874173 1.281162309297293 +P12695 1.4623588289973064 1.8735190143794742 0.4111601853821678 1.281162309297293 +P38858 0.22424654530886826 0.3889504592903252 0.16470391398145692 1.734476929196837 +Q12189 0.07811292097030514 0.1115438284145193 0.03343090744421416 1.4279817862261612 +P33330 0.539780266736367 0.5500270627652998 0.010246796028932748 1.0189832727507568 diff --git a/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu021.tsv b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu021.tsv new file mode 100644 index 0000000..112c8a2 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu021.tsv @@ -0,0 +1,6 @@ +protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change +P32473 0.4770052046585751 0.6193900013511184 0.14238479669254334 1.298497365022375 +P16387 0.5519012383155827 0.7166423037053699 0.16474106538978717 1.2984973650223748 +P16451 0.2701092287127663 0.35073612175175306 0.08062689303898674 1.2984973650223748 +P12695 1.5427582572900365 2.0032675319576234 0.46050927466758695 1.2984973650223748 +Q12189 0.08505245268844289 0.09714930131724593 0.012096848628803045 1.1422280986195097 diff --git a/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu025.tsv b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu025.tsv new file mode 100644 index 0000000..5a6f3cb --- /dev/null +++ b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu025.tsv @@ -0,0 +1,8 @@ +protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change +P32473 0.6670875336960653 0.7466775954256141 0.07959006172954874 1.1193097722701728 +P16387 0.7718289702420922 0.8639157089131981 0.09208673867110595 1.1193097722701728 +P16451 0.37774535256804465 0.4228140645590542 0.045068711991009536 1.1193097722701728 +P12695 2.1575336933304237 2.4149485469469014 0.25741485361647776 1.1193097722701728 +P38152 0.1781722158652424 0.1972976087278044 0.019125392862562013 1.1073421732433704 +P09624 0.6733529618763209 0.6739909308127159 0.0006379689363950058 1.0009474509989786 +Q12189 0.12038340867713954 0.1279818858309837 0.007598477153844152 1.0631189732650184 diff --git a/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu028.tsv b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu028.tsv new file mode 100644 index 0000000..0cf96f0 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu028.tsv @@ -0,0 +1 @@ +protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change diff --git a/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu033.tsv b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu033.tsv new file mode 100644 index 0000000..0ab2f37 --- /dev/null +++ b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu033.tsv @@ -0,0 +1,8 @@ +protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change +P32473 0.8555770615704378 0.8788196489186719 0.023242587348234145 1.027165977668419 +P16387 0.9899138104648423 1.0168057869335898 0.026891976468747525 1.027165977668419 +P16451 0.4844795359634268 0.4976408962182153 0.013161360254788479 1.027165977668419 +P12695 2.767157598270893 2.842330139790516 0.07517254151962316 1.027165977668419 +P09624 0.7814889160669622 0.8091253176948288 0.027636401627866514 1.035363779395559 +Q12189 0.06745410205346074 0.09212604794012445 0.024671945886663715 1.3657590144348815 +Q99297 0.2396549173630842 0.2686294526491298 0.0289745352860456 1.12090106727144 diff --git a/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu038.tsv b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu038.tsv new file mode 100644 index 0000000..d12ec8e --- /dev/null +++ b/literature/xia2022/results/modelGeneration/relaxedEnzymes_mu038.tsv @@ -0,0 +1,10 @@ +protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change +P32473 0.7405773775919637 0.8750790030609921 0.13450162546902833 1.181617248296686 +P16387 0.8568576773791474 1.012477810926638 0.1556201335474905 1.1816172482966862 +P16451 0.4193597518640667 0.4955227160439996 0.0761629641799329 1.1816172482966862 +P12695 2.3952188640373233 2.8302319231920965 0.4350130591547732 1.1816172482966862 +P09624 0.6780395117986583 0.8077552676031177 0.12971575580445938 1.1913100247806474 +P00359 13.214386076683002 13.385528343827934 0.17114226714493164 1.012951208338533 +Q04013 0.16739268679725083 0.1785827143159672 0.011190027518716367 1.0668489629554123 +Q12189 0.07152482166150763 0.13246268161298877 0.06093785995148114 1.8519819908097157 +Q99297 0.27494172029105823 0.3031514557665901 0.02820973547553185 1.1026026004553566 diff --git a/literature/xia2022/results/modelGeneration/respiratoryKcats.tsv b/literature/xia2022/results/modelGeneration/respiratoryKcats.tsv new file mode 100644 index 0000000..cd847eb --- /dev/null +++ b/literature/xia2022/results/modelGeneration/respiratoryKcats.tsv @@ -0,0 +1,4 @@ +complex reaction condition kcat_per_s ecmodel_kcat_per_s +ATP synthase r_0226 mu038 447.037089 84.649052 +complex III r_0439 mu038 426.978118 290.494288 +complex IV r_0438 mu038 1090.333553 1376.34631 diff --git a/literature/xia2022/results/modelGeneration/respiratoryTurnover.tsv b/literature/xia2022/results/modelGeneration/respiratoryTurnover.tsv new file mode 100644 index 0000000..7731f6a --- /dev/null +++ b/literature/xia2022/results/modelGeneration/respiratoryTurnover.tsv @@ -0,0 +1,28 @@ +condition complex reaction flux_mmol_gDW_h abundance_nmol_gDW apparent_turnover_per_s ecmodel_kcat_per_s relative_to_highest +mu003 complex III r_0439 1.923188 7.759567 68.846474 290.494288 0.161241 +mu003 complex IV r_0438 3.846873 5.854775 182.513545 1376.34631 0.167392 +mu003 ATP synthase r_0226 2.500026 7.736123 89.767414 84.649052 0.200805 +mu004 complex III r_0439 3.493436 7.509998 129.214252 290.494288 0.302625 +mu004 complex IV r_0438 6.988096 6.605673 293.859184 1376.34631 0.269513 +mu004 ATP synthase r_0226 4.548627 10.018748 126.114301 84.649052 0.282111 +mu010 complex III r_0439 5.517784 11.502942 133.245725 290.494288 0.312067 +mu010 complex IV r_0438 11.036144 6.581974 465.756213 1376.34631 0.427169 +mu010 ATP synthase r_0226 7.161085 13.875473 143.36018 84.649052 0.32069 +mu015 complex III r_0439 9.233089 13.279189 193.140318 290.494288 0.452342 +mu015 complex IV r_0438 18.467975 10.804601 474.797092 1376.34631 0.43546 +mu015 ATP synthase r_0226 12.075794 17.374358 193.065391 84.649052 0.431878 +mu021 complex III r_0439 12.845536 11.035018 323.352843 290.494288 0.757305 +mu021 complex IV r_0438 25.693048 8.542592 835.455758 1376.34631 0.766239 +mu021 ATP synthase r_0226 16.607718 15.547107 296.727563 84.649052 0.663765 +mu025 complex III r_0439 13.456705 13.471169 277.479524 290.494288 0.649868 +mu025 complex IV r_0438 26.915485 11.240028 665.169457 1376.34631 0.610061 +mu025 ATP synthase r_0226 17.590032 19.601226 249.27624 84.649052 0.557619 +mu028 complex III r_0439 18.215073 15.746638 321.322085 290.494288 0.752549 +mu028 complex IV r_0438 36.43385 12.608939 802.645955 1376.34631 0.736147 +mu028 ATP synthase r_0226 23.577733 19.346141 338.536259 84.649052 0.757289 +mu033 complex III r_0439 22.03541 16.678425 366.997905 290.494288 0.859524 +mu033 complex IV r_0438 44.07635 13.081623 935.925963 1376.34631 0.858385 +mu033 ATP synthase r_0226 28.686084 19.028098 418.7679 84.649052 0.936763 +mu038 complex III r_0439 21.878037 14.233124 426.978118 290.494288 1.0 +mu038 complex IV r_0438 43.760184 11.148521 1090.333553 1376.34631 1.0 +mu038 ATP synthase r_0226 28.14282 17.487251 447.037089 84.649052 1.0 diff --git a/literature/xia2022/results/modelGeneration/summary.tsv b/literature/xia2022/results/modelGeneration/summary.tsv new file mode 100644 index 0000000..173025a --- /dev/null +++ b/literature/xia2022/results/modelGeneration/summary.tsv @@ -0,0 +1,10 @@ +condition f Ptot_measured Ptot_rescaled GAM pool_mg_gDW proteins_kept model_enzymes_measured raised_to_minimum flexibilized pool_increases rates_relaxed rates_added_mg NGAM NGAM_error growth glucose CO2 O2 pool_used_mg_gDW ethanol +mu003 0.4883 0.299 0.3201 55.3 156.3 2013 624 7 0 0 0 0.0 0.4 0.1617 0.027 0.3781 0.9722 0.8265 8.0 0.0 +mu004 0.5058 0.312 0.3374 55.3 170.7 1933 622 8 0 0 0 0.0 0.85 0.1729 0.044 0.5732 1.6231 1.4596 13.5 0.0 +mu010 0.5113 0.371 0.3926 55.3 200.7 1978 608 11 3 0 5 0.75 0.0 inf 0.10225 1.3273 3.1159 2.8081 29.9 0.0 +mu015 0.5094 0.419 0.4394 55.3 223.9 1862 586 14 11 0 7 0.97 0.0 inf 0.152 1.8597 4.5004 4.0802 43.9 0.0 +mu021 0.5043 0.32 0.3381 55.3 170.5 1726 573 16 13 0 5 0.86 0.0 0.2623 0.21425 2.7534 6.8708 6.3749 79.6 0.0 +mu025 0.498 0.378 0.39 55.3 194.2 1825 572 19 14 0 7 0.5 0.0 0.2771 0.254 3.1461 7.9032 6.8503 76.8 0.01 +mu028 0.4928 0.391 0.4209 55.3 207.4 1957 607 26 15 0 0 0.0 0.0 0.2339 0.28425 3.6455 9.803 8.6654 100.3 0.0 +mu033 0.4696 0.419 0.4245 55.3 199.3 1795 581 29 15 0 7 0.22 0.0 0.1819 0.33375 5.6624 13.0553 9.1107 111.9 1.8424 +mu038 0.4595 0.391 0.4117 55.3 189.2 1754 547 28 17 0 9 1.2 0.0 0.2263 0.3785 7.78 16.6871 9.6094 131.8 4.8984 diff --git a/literature/xia2022/results/randomSampling/allFluxes.tsv b/literature/xia2022/results/randomSampling/allFluxes.tsv new file mode 100644 index 0000000..8fa45bc --- /dev/null +++ b/literature/xia2022/results/randomSampling/allFluxes.tsv @@ -0,0 +1,4106 @@ +rxnID rxnName mu003_AVERAGE mu003_STDEV mu003_STDEV_percent mu004_AVERAGE mu004_STDEV mu004_STDEV_percent mu010_AVERAGE mu010_STDEV mu010_STDEV_percent mu015_AVERAGE mu015_STDEV mu015_STDEV_percent mu021_AVERAGE mu021_STDEV mu021_STDEV_percent mu025_AVERAGE mu025_STDEV mu025_STDEV_percent mu028_AVERAGE mu028_STDEV mu028_STDEV_percent mu033_AVERAGE mu033_STDEV mu033_STDEV_percent mu038_AVERAGE mu038_STDEV mu038_STDEV_percent +r_0001 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.0001242189593371 0.0027776203043727 2236.067923282684 0.0003075899831383 0.0056025866556568 1821.4463938305528 0.0001694041022585 0.0039944568907062 2357.945786111681 0.0004659807071063 0.0074388486002479 1596.385534165424 0.0004999756238599 0.0118587282303546 2371.8612797163423 0.0006607672585017 0.0124717736164252 1887.468462754206 0.0006084786369285 0.0159933395673695 2628.4143101718046 0.0015914884641912 0.0313577230785814 1970.339325991716 0.000759868020398 0.021924879598084 2885.353641622961 +r_0002 (R)-lactate:ferricytochrome-c 2-oxidoreductase 8.477756042147613e-05 0.0022669247687344 2673.967919652752 0.0001243304128205 0.0031183450875516 2508.111263212808 5.7138485132495286e-05 0.0023344805559505 4085.6535670086864 0.0002770654709279 0.0059983063134208 2164.941843287754 0.0001738076518225 0.0070942443583996 4081.6640027109097 0.0002366737530409 0.0074812841675239 3161.011337928177 0.0007032442249352 0.0170304537730961 2421.698347350698 0.0006608620823951 0.0208899228705028 3161.010962346548 0.000507881682421 0.0179509140130186 3534.4676987456 +r_0003 (R,R)-butanediol dehydrogenase -0.0015070825174226 0.0062839093278426 -416.9585444192699 -6.305953347999993e-05 0.0011576634324264 -1835.8261923926084 -0.0001913371173377 0.0034233427901481 -1789.1681644311898 -0.0001223367881366 0.0025356126323256 -2072.6493403551744 -0.0005083854191213 0.0096208375828497 -1892.4298811474628 -0.0011805449827427 0.0121992120048953 -1033.3542713936592 -0.0007819630571066 0.01382761712777 -1768.321022598487 -0.0017768140642608 0.022494416390013 -1265.997204911319 -0.000999675184675 0.0203790433044207 -2038.5664880784127 +r_0004 (S)-lactate:ferricytochrome-c 2-oxidoreductase 3.965565824164086e-05 0.0014015466002823 3534.291605354517 0.000180460278779 0.0040315519061851 2234.0383897567463 6.0990514868384096e-05 0.0021556313825066 3534.371511961218 0.0001557337229665 0.0041615617558219 2672.2290307762423 0.00031413045599 0.008390540409649 2671.0369050987824 0.0001398485677077 0.0049581434151183 3545.3658885363025 0.0005404078602079 0.0135007151584561 2498.2455202003243 0.0005129291413063 0.0162136959012718 3161.0011199555684 0.0007873600551773 0.019670234398197 2498.251501184668 +r_0005 1,3-beta-glucan synthase 0.0221827319060365 0.0001638983425807 0.7388555353553803 0.0352109724168642 0.0002172308991906 0.6169409257400288 0.0719847351085531 0.0002028209930086 0.2817555592901437 0.0951762712119291 0.0002576745890369 0.2707340661236697 0.1686062664451045 0.0007099091654679 0.4210455402611636 0.1759469226855546 0.0005124671632756 0.2912623622247373 0.1909851492000209 0.0009023419208287 0.4724670607156489 0.2091293690278902 0.0012276677048788 0.5870374450922505 0.2543210653456536 0.0012804131730304 0.5034632783132714 +r_0006 1,6-beta-glucan synthase 0.0074116507393444 5.476143076826326e-05 0.7388560618158218 0.0117646207357408 7.25807858873319e-05 0.6169411451304305 0.0240513978730173 6.776616100127479e-05 0.2817556025602147 0.0318001082419399 8.609375244011282e-05 0.2707341490321314 0.0563343934969221 0.000237193456595 0.4210455493906953 0.0587870391295457 0.0001712245508083 0.291262416586398 0.0638115817279814 0.0003014887311711 0.472467102376976 0.0698738927418542 0.0004101859384688 0.5870374790542258 0.0849732532553114 0.0004278091393548 0.5034632934076553 +r_0007 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase 0.0012210915771837 9.021931166536272e-06 0.7388414870032893 0.0020758457702125 1.2806641836838752e-05 0.6169360951862737 0.0057321391952357 1.615044921403674e-05 0.2817525650364555 0.0096234216258816 2.605370946226468e-05 0.2707322870713116 0.0103630930236677 4.3633162871352114e-05 0.421043821296408 0.0145089306513367 4.2258876478896095e-05 0.2912611376704218 0.0168020079876638 7.938376625226801e-05 0.4724659475852663 0.0211453987638836 0.0001241312340728 0.5870366194506329 0.0223740152239199 0.0001126447669531 0.5034624577920431 +r_0012 1-pyrroline-5-carboxylate dehydrogenase 0.0001680507053807 0.0024222486204127 1441.379621064055 0.0004968622000998 0.0055607508183232 1119.1736495966668 0.0002805427351237 0.0039228650640689 1398.3128318537651 0.0005099235750886 0.0063807384834838 1251.3127055117031 0.0010119699383173 0.0127639652374202 1261.2988542568055 0.0005062499639358 0.0081084589376008 1601.6710153540278 0.0014673055883586 0.0188477755315544 1284.5160327262074 0.0021254445713791 0.0277662492310807 1306.3737161145286 0.0020585012177548 0.0268991036437994 1306.732462035534 +r_0013 2,3-diketo-5-methylthio-1-phosphopentane degradation reaction 7.834208178750116e-05 0.0007219675433728 921.5577718896268 0.0001164219440995 0.0011873339059774 1019.8540448376192 0.0001103089926396 0.0010053042359157 911.3529294931504 0.0001522751418464 0.0013893804234945 912.41446676538 0.0003528110043817 0.0031487233307096 892.4674376942667 0.0003211544693242 0.0027870201415974 867.8129709548583 0.0004018975437401 0.004078772553986 1014.8786967016676 0.0006911232925013 0.006750131082242 976.689854832082 0.0007068345100315 0.0066813847647657 945.254464792284 +r_0014 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase 2.271524373492777e-05 1.6789948919537965e-07 0.7391489660188474 3.700710460573424e-05 2.2842819800148698e-07 0.6172549850497953 8.593981847370838e-05 2.4215496332014535e-07 0.2817727191199827 0.000127752127615 3.458947445841955e-07 0.2707545862770719 0.0001801328257654 7.585244344111533e-07 0.4210917311644894 0.0002135013600163 6.215664813219208e-07 0.291129986841446 0.000239022656492 1.1292799168216475e-06 0.4724572696978624 0.0002807095357251 1.6477928317304745e-06 0.5870099237895661 0.0003182893608867 1.6024667769665324e-06 0.5034622497284283 +r_0015 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH) 2.271524373492777e-05 1.6789948919537965e-07 0.7391489660188474 3.700710460573424e-05 2.2842819800148698e-07 0.6172549850497953 8.593981847370838e-05 2.4215496332014535e-07 0.2817727191199827 0.000127752127615 3.458947445841955e-07 0.2707545862770719 0.0001801328257654 7.585244344111523e-07 0.4210917311644888 0.0002135013600163 6.215664813219211e-07 0.2911299868414461 0.000239022656492 1.1292799168216456e-06 0.4724572696978615 0.0002807095357251 1.6477928317304747e-06 0.5870099237895662 0.0003182893608867 1.6024667769665324e-06 0.5034622497284283 +r_0016 2-aceto-2-hydroxybutanoate synthase 0.0042211911330579 0.0030707206928651 72.7453601618999 0.0066940572265752 0.0011505808435696 17.188093926085486 0.0184809547492617 0.0028310934783083 15.318978465771313 0.0309042586543443 0.0033751935751223 10.921451353591523 0.0336361144822849 0.0079457980821438 23.622817927821654 0.0470225431466737 0.0089587810545294 19.05209811086793 0.0544810842792153 0.0121277819668934 22.260537078775084 0.0687090247361664 0.017115599801579 24.910264506446893 0.0726517220583299 0.0169596819908387 23.34381279664963 +r_0017 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 3.370515101503023e-10 4.8449982631679216e-08 14374.65229278272 7.861186484005374e-10 7.72279260524707e-08 9823.952937587876 2.963720311913668e-09 1.566510730528506e-07 5285.622682516264 8.256305050977742e-09 2.5739099070660414e-07 3117.5082451213807 9.341492679709922e-09 3.275050967611879e-07 3505.918250865212 1.9119281676306145e-08 5.106867850585378e-07 2671.0563383320723 1.8421831546011652e-08 5.315487249059342e-07 2885.428213683862 2.537681000881e-08 6.778734258068012e-07 2671.2318276862443 1.6442451818481158e-08 5.802016834648602e-07 3528.6810621072887 +r_0018 2-aminoadipate transaminase 0.004813227326796 3.556267182060622e-05 0.7388529443149939 0.0081824453907497 5.0480787401053e-05 0.616940107637278 0.022594599529601 6.366143382880476e-05 0.2817550881811481 0.0379330186829625 0.000102697486902 0.2707337577333328 0.0408486101048924 0.0001719910494753 0.4210450466582642 0.0571904195277281 0.0001665740336442 0.2912621292513366 0.0662291318641015 0.0003129107419644 0.472466923779927 0.0833496440291107 0.0004892934691728 0.5870372631728625 0.0881925296371844 0.0004440169180408 0.5034631843166931 +r_0019 2-dehydropantoate 2-reductase 4.3147969881399005e-06 3.1292272186927546e-08 0.7252316220888431 7.030547087741129e-06 4.3498890745523966e-08 0.618712743157231 1.6327724306128466e-05 4.5985109812123784e-08 0.2816382059737723 2.4272181125290883e-05 6.59584295239346e-08 0.2717449626115714 3.422433658109372e-05 1.4398309804550876e-07 0.4207038395159081 4.0564295146042406e-05 1.1848497563001853e-07 0.292091789598317 4.541351676309623e-05 2.1456103222008586e-07 0.4724607286842883 5.333376783807367e-05 3.129632509573028e-07 0.5868013148958248 6.047408065625624e-05 3.04371757106293e-07 0.5033094406782102 +r_0020 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.0052036040195815 0.0018701166319442 35.93887284479828 0.0085591365412619 0.0016032650909514 18.73162185487317 0.0234086327463921 0.0029191679314326 12.47047601224208 0.0390438620665965 0.003828058293807 9.80450726743578 0.0427175648851997 0.0072635454484343 17.00365053100416 0.0591844219041012 0.0072112578109409 12.18438497654951 0.0690375188209769 0.0111956780611244 16.21680247541383 0.0871159029810305 0.0171509635680712 19.68752315154885 0.0918926165263695 0.0156337565318725 17.013071477169557 +r_0021 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase -3.573787597845846e-10 2.9275360457156436e-10 -81.91690092271459 -3.4303333333472275e-10 5.726070188001368e-11 -16.692459978558475 -3.1193333333335736e-10 2.2970351292890388e-10 -73.63865556600328 -3.4893333332778447e-10 6.334822929933154e-11 -18.154823070406646 -3.4286666666670365e-10 9.871371621230294e-11 -28.79070082022913 -2.9193333326997896e-10 2.3654341273915874e-10 -81.02651728379513 -2.766333333443469e-10 1.9179914449250677e-10 -69.33334539759154 -2.6873333333604863e-10 3.2636606690790473e-10 -121.44606806174912 -3.3896666667221235e-10 1.4937073598176647e-10 -44.066496994588256 +r_0022 2-hexaprenyl-6-methoxyphenol monooxygenase -3.573787597845846e-10 2.9275360457156436e-10 -81.91690092271459 -3.4303333333472275e-10 5.726070188001368e-11 -16.692459978558475 -3.1193333333335736e-10 2.2970351292890388e-10 -73.63865556600328 -3.4893333332778447e-10 6.334822929933154e-11 -18.154823070406646 -3.4286666666670365e-10 9.871371621230294e-11 -28.79070082022913 -2.9193333326997896e-10 2.3654341273915874e-10 -81.02651728379513 -2.766333333443469e-10 1.9179914449250677e-10 -69.33334539759154 -2.6873333333604863e-10 3.2636606690790473e-10 -121.44606806174912 -3.3896666667221235e-10 1.4937073598176647e-10 -44.066496994588256 +r_0023 2-isopropylmalate hydratase -0.0055361483530767 0.0026470011078929 -47.81304508254027 -0.0090725803215414 0.0009238723326683 -10.18312651886627 -0.0250415470551878 0.0022349161119548 -8.924832427602787 -0.0419875972847876 0.0027958413873794 -6.658731549738829 -0.0455458636443973 0.0070584338713037 -15.497420196953527 -0.0634715065116324 0.0064950819547184 -10.233067263856563 -0.0737759722154493 0.0104911606566913 -14.220294686261616 -0.0928061717651591 0.0144157128083743 -15.533140236462405 -0.0981188119187107 0.0139315685319901 -14.19867226228965 +r_0024 2-isopropylmalate synthase 3.925002216285578e-05 0.0004534169527184 1155.2017750134717 5.401274105156175e-05 0.0006952883191828 1287.2672366676386 0.000140253296125 0.0019192454237918 1368.413774803881 0.0001906716631787 0.0027576777455031 1446.2965810072012 0.0001616917505863 0.0026902784688173 1663.831617297482 0.0003279810288576 0.0044152293540474 1346.1843721345251 0.000262006777959 0.0043593594914768 1663.834624979562 0.0003846558607874 0.005923491048471 1539.945611733139 0.0003296390419459 0.0056442107244587 1712.239755078332 +r_0025 2-isopropylmalate synthase 0.0055438237767022 0.0030042672217435 54.191246741443344 0.009035421986526 0.0012763961399187 14.126580272866162 0.0250563962037132 0.0038223441649336 15.254963777940384 0.0419038317913852 0.0044666764507553 10.6593508512357 0.0456172951515272 0.0092721682679002 20.325993106563608 0.0634764533835312 0.0098885084879098 15.578230919995583 0.0738959932175145 0.0142085440963519 19.22775982525704 0.0931034697267721 0.0209024458216121 22.450769969104144 0.0982908174937584 0.0191169548041249 19.44938020821616 +r_0026 2-keto-4-methylthiobutyrate transamination 5.904294085418942e-05 0.0006525095187937 1105.1440008808968 9.949341908318408e-05 0.0011525094639577 1158.3775837417045 9.72830146080166e-05 0.0009676448496644 994.6698851422008 0.0001196229831995 0.0012877144783024 1076.4774827211725 0.0002969587919572 0.0029970862508445 1009.2599821985268 0.0002571915725434 0.0025821465631496 1003.9779055021082 0.0003283933532828 0.0038419617869091 1169.9267809480891 0.0005665201383597 0.0063930021506331 1128.4686488185464 0.0005775086431666 0.0063153521077689 1093.551097891874 +r_0027 2-methylcitrate dehydratase 0.0048132272607936 3.5562686012007606e-05 0.7388532492883723 0.0081824452387841 5.0480819421499503e-05 0.6169405104262032 0.0225945993771964 6.366146575899787e-05 0.2817552313994466 0.0379330185749148 0.0001026975097591 0.270733818760794 0.0408486101048924 0.0001719910494753 0.4210450466582642 0.0571904194436072 0.0001665740527099 0.2912621630170617 0.0662291317364671 0.0003129107706179 0.4724669679546817 0.0833496439463349 0.0004892934872609 0.587037285457352 0.0881925294363884 0.0004440169619329 0.5034632352315446 +r_0028 2-methylcitrate synthase 1.40758437259623e-05 0.0004448215083064 3160.1765191950544 0.0001412729342032 0.001538134785996 1088.7682022539052 9.688439548988284e-05 0.0015171922548135 1565.9820625829648 0.0001382676929956 0.0021501463748862 1555.0605700451931 0.0002789801104243 0.0040299106045713 1444.5153808428015 0.000140783099587 0.0025941983339369 1842.691588369252 0.0003923802770424 0.0058898748220155 1501.0629143773308 0.00048450121511 0.0077971879661726 1609.3226854758857 0.000519284440575 0.0079842360214296 1537.5457836919152 +r_0029 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.0055361487682767 0.0026470011035353 47.8130414179471 0.0090725800262849 0.0009238723850119 10.183127427206877 0.0250415469659708 0.002234916130427 8.924832533166116 0.0419875969097195 0.0027958414606283 6.65873178367375 0.0455458633159582 0.0070584339329372 15.497420444029922 0.0634715067005713 0.0064950819453265 10.233067218598206 0.0737759720860828 0.0104911607046666 14.220294776225236 0.0928061713037636 0.0144157128867219 15.533140398107689 0.0981188115948707 0.0139315685872326 14.198672365453872 +r_0030 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0032 3',5'-bisphosphate nucleotidase 0.0019950416288424 0.0021375339373532 107.14232256865056 0.0032582029998773 0.0027790128799933 85.29280956705166 0.0083576874199219 0.0021729531683135 25.999454862764203 0.0140750605691567 0.0034103991676344 24.230085198409927 0.0153016846012292 0.0062395015170469 40.77656597722403 0.0213345184712777 0.0063621349734084 29.82085103994087 0.0249362705103711 0.0107971410010716 43.29894078018241 0.0315063994623848 0.0158319406868077 50.249920514432 0.0331954753035035 0.0148228670557672 44.65327554506434 +r_0033 3',5'-cyclic-nucleotide phosphodiesterase 8.858605837695744e-05 0.0019790605639627 2234.054206973842 0.0001773820592405 0.0037780137637164 2129.873663600516 0.0001497681075375 0.0031898794251032 2129.8789692609976 0.0002414662373018 0.0049234847955439 2038.995120211691 0.0003212528820033 0.0080257094175405 2498.252892703244 0.0003608862236308 0.0076864423668144 2129.8796860356847 0.0005435004708994 0.0128001759502525 2355.136128781926 0.0008250617180921 0.0194313243500104 2355.135855162714 0.0007041409699226 0.0175912140603283 2498.251743860484 +r_0034 3',5'-cyclic-nucleotide phosphodiesterase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0035 3',5'-cyclic-nucleotide phosphodiesterase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0036 3',5'-cyclic-nucleotide phosphodiesterase 4.429305766028359e-05 0.0014001089753928 3161.0122428921068 8.062876411681367e-05 0.0025486850797622 3161.012211559808 5.449955313032671e-05 0.0019262718158499 3534.472679516499 0.0001006361219772 0.0031811201365266 3161.0122429470475 0.0001342927357804 0.0049623762382455 3695.1933471362886 0.0001313299679502 0.0046418220931276 3534.4728743760647 0.0003020073127656 0.0095464881311463 3161.0122429564112 0.0003650884556442 0.0129043294169266 3534.5761328323206 0.000264199718947 0.010783747611429 4081.665057936285 +r_0037 3',5'-cyclic-nucleotide phosphodiesterase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0038 3,4-dihydroxy-2-butanone-4-phosphate synthase 4.543121265431256e-05 3.3557979130544466e-07 0.7386547082924712 7.401504379065325e-05 4.566688662576915e-07 0.6169946579364997 0.0001718799276096 4.842374291644184e-07 0.2817300634802316 0.0002555047405979 6.916769263603523e-07 0.2707100168637339 0.0003602664763946 1.5168500154262989e-06 0.4210355708380148 0.0004270003661968 1.2436171809886648e-06 0.2912449916764805 0.0004780455503919 2.2585061251396865e-06 0.4724458000472563 0.0005614189923658 3.295601791357086e-06 0.5870128791812803 0.0006365790537736 3.204861628702823e-06 0.5034506884422627 +r_0039 3-dehydroquinate dehydratase 0.0052205259442072 0.0018452916334718 35.34685304110687 0.0085911211558188 0.0015329995362894 17.843998571142254 0.0234777578226843 0.0026533896684269 11.301716665052377 0.0391133977095598 0.0034503658296924 8.821442349021886 0.0428365307734951 0.0069640715401313 16.257319195513272 0.0593364683675767 0.006629716167228 11.173088573722188 0.0691322083053571 0.0108932693696886 15.757155219999646 0.0873769259750843 0.0165973939258096 18.99516804990648 0.0920948624104587 0.0151617995402076 16.463241426685546 +r_0040 3-dehydroquinate synthase 0.0052205259442072 0.0018452916334718 35.34685304110687 0.0085911211558188 0.0015329995362894 17.843998571142254 0.0234777578226843 0.0026533896684269 11.301716665052377 0.0391133977095598 0.0034503658296924 8.821442349021886 0.0428365307734951 0.0069640715401313 16.257319195513272 0.0593364683675767 0.006629716167228 11.173088573722188 0.0691322083053571 0.0108932693696886 15.757155219999646 0.0873769259750843 0.0165973939258096 18.99516804990648 0.0920948624104587 0.0151617995402076 16.463241426685546 +r_0041 3-dehydrosphinganine reductase -1.9469628306220788e-10 1.6315599867639483e-09 -838.002637288481 -2.8606795849931005e-10 2.3729727480216114e-09 -829.5136444046508 -2.5970333427871677e-10 1.7655281247457551e-09 -679.8249740032096 -3.565839694955152e-10 2.3723664502917163e-09 -665.3037301839655 -3.44460646691842e-10 2.127516978098891e-09 -617.637166547559 -2.1608373516611096e-10 2.0191449460763e-09 -934.427084261624 -2.5356730974661477e-10 1.7687947082483112e-09 -697.5641734006784 -2.1988151777847176e-10 1.77847019372856e-09 -808.8311431069661 -1.8896275510597438e-10 1.549206181520817e-09 -819.8473718548339 +r_0042 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 1.6921924625699864e-05 0.0002876585498577 1699.9162696948235 3.1984614556897414e-05 0.0005658152392545 1769.0231603324803 6.912507629218237e-05 0.0013250713833154 1916.918511184781 6.953564296331383e-05 0.0016375174486469 2354.932490537049 0.0001189658882953 0.0024300403150377 2042.636212663148 0.0001520464634754 0.0031397185736318 2064.973102211261 9.468948438015534e-05 0.0025285287682268 2670.3374559263443 0.0002610229940537 0.0051774065922724 1983.505940172784 0.0002022458840892 0.0047584729215579 2352.815704006542 +r_0043 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase -4.1733333333333107e-11 1.878499630898041e-10 -450.1197198637502 -7.513204228042823e-11 4.130214031910956e-10 -549.7273741734649 -3.5466666666666553e-11 1.7861705383724655e-10 -503.619512699005 -5.359999999441368e-11 2.333908044112512e-10 -435.43060529025325 -3.1666666666666596e-11 1.9721533887882944e-10 -622.785280669989 -4.553333333333293e-11 1.6785945120567195e-10 -368.65179620572496 -6.646666667769803e-11 2.1294789772405887e-10 -320.38299551963337 -1.4293333333333222e-10 3.3332175748387165e-10 -233.20085644860603 -2.127333333388507e-10 1.845601595465033e-10 -86.75657765984799 +r_0044 3-hexaprenyl-4-hydroxy-5-methoxybenzoate decarboxylase -3.573787597845846e-10 2.9275360457156436e-10 -81.91690092271459 -3.4303333333472275e-10 5.726070188001368e-11 -16.692459978558475 -3.1193333333335736e-10 2.2970351292890388e-10 -73.63865556600328 -3.4893333332778447e-10 6.334822929933154e-11 -18.154823070406646 -3.4286666666670365e-10 9.871371621230294e-11 -28.79070082022913 -2.9193333326997896e-10 2.3654341273915874e-10 -81.02651728379513 -2.766333333443469e-10 1.9179914449250677e-10 -69.33334539759154 -2.6873333333604863e-10 3.2636606690790473e-10 -121.44606806174912 -3.3896666667221235e-10 1.4937073598176647e-10 -44.066496994588256 +r_0045 3-hydroxy-L-kynurenine hydrolase 0.0001378827306078 1.0101320085441578e-06 0.7326022657738075 0.0002246330887973 1.371259074026349e-06 0.610443938320989 0.000521658306396 1.4691516407787671e-06 0.2816310260500815 0.0007754600284313 2.099279363171996e-06 0.2707140647105455 0.0010934112804882 4.602982065647615e-06 0.4209744446382621 0.0012959484111734 3.7746786456193073e-06 0.2912676625917184 0.0014508701543442 6.85346155801346e-06 0.4723690495315799 0.0017039072121787 1.0001094368091705e-05 0.5869506447656476 0.0019320197466961 9.725921543180264e-06 0.5034069429058463 +r_0057 3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA) 0.0002090015703217 0.0015207981593946 727.6491545272543 0.0003197672980343 0.0019236525924125 601.5788994801907 0.0003104013245283 0.0023440650718287 755.1723805915781 0.0004377289124604 0.0032684849624291 746.6915868218442 0.0008817518618033 0.0062527347672168 709.1263470007252 0.0007309436712479 0.0039635473219108 542.2507202427232 0.0015390036007872 0.0102683117637413 667.2051812281993 0.0029030280405835 0.0184364688049741 635.077186552704 0.0023280656738822 0.0165320779539908 710.1207727710853 +r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.0001378813695019 1.0104321004530094e-06 0.7328271427116259 0.0002246299569344 1.3719673516600782e-06 0.6107677579533831 0.0005216581405101 1.4691864205957885e-06 0.2816377827745733 0.0007754596616438 2.099357009344359e-06 0.2707242056787257 0.0010934110914475 4.603022832963794e-06 0.4209782458736368 0.0012959484026904 3.774680951223164e-06 0.2912678424069011 0.0014508700434777 6.853486452185516e-06 0.4723708014370139 0.001703907356015 1.00010642601968e-05 0.5869488282265916 0.0019320191408856 9.72605397363874e-06 0.5034139552665151 +r_0059 3-isopropylmalate 3-methyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0060 3-isopropylmalate dehydratase -0.0055361483530767 0.0026470011078929 -47.81304508254027 -0.0090725803215414 0.0009238723326683 -10.18312651886627 -0.0250415470551878 0.0022349161119548 -8.924832427602787 -0.0419875972847876 0.0027958413873794 -6.658731549738828 -0.0455458636443973 0.0070584338713037 -15.497420196953527 -0.0634715065116324 0.0064950819547184 -10.233067263856563 -0.0737759722154493 0.0104911606566913 -14.220294686261616 -0.0928061717651591 0.0144157128083743 -15.533140236462405 -0.0981188119187107 0.0139315685319901 -14.19867226228965 +r_0061 3-isopropylmalate dehydrogenase 0.0055361483530767 0.0026470011078929 47.81304508254027 0.0090725803215414 0.0009238723326683 10.18312651886627 0.0250415470551878 0.0022349161119548 8.924832427602787 0.0419875972847876 0.0027958413873794 6.658731549738828 0.0455458636443973 0.0070584338713037 15.497420196953524 0.0634715065116324 0.0064950819547184 10.233067263856563 0.0737759722154493 0.0104911606566913 14.220294686261616 0.0928061717651591 0.0144157128083743 15.533140236462405 0.0981188119187107 0.0139315685319901 14.19867226228965 +r_0062 3-methyl-2-oxobutanoate decarboxylase 0.0005197728424562 0.0046089917465449 886.7319278869878 0.0001274478092286 0.0014689602116885 1152.597459759134 0.0004381272778541 0.0041273484778737 942.0432569478368 0.0003752698627054 0.0039986730760403 1065.546017261467 0.0008674590481829 0.0101324767178381 1168.063984007324 0.0013337659179991 0.0119852727488101 898.6039144552677 0.0015181017562803 0.0160803679566593 1059.2417728347118 0.0024347903722247 0.025554136787296 1049.541557203811 0.0022309524735128 0.0241837206595642 1084.008778613075 +r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 4.314660801926394e-06 3.1327426273983755e-08 0.7260692720038804 7.0306792795838905e-06 4.347528477292475e-08 0.6183653533901183 1.6328078115727947e-05 4.592085079595225e-08 0.2812385540446379 2.4272224584312e-05 6.595025279106725e-08 0.271710788444555 3.4224436524497786e-05 1.4396255134532574e-07 0.420642575787267 4.056428904453467e-05 1.1848666676652649e-07 0.2920960025613723 4.541402555270658e-05 2.1444967940420573e-07 0.4722102407665223 5.333385524258549e-05 3.129446100616228e-07 0.586765401897566 6.047406169599492e-05 3.043762665126233e-07 0.5033170552405306 +r_0064 3-methyl-2-oxopentanoate decarboxylase 0.0002663101381103 0.0024994286434246 938.5405531911188 6.946238621770931e-05 0.000916029095865 1318.7411860484865 0.0001605879502921 0.0020164479075418 1255.6657606458134 0.0002141199759697 0.0025654105328255 1198.1182611323443 0.0004120416969474 0.0055820450978795 1354.7282081481546 0.0005100420724175 0.0059079462897801 1158.3252851626028 0.0006139172041352 0.0082883763259923 1350.0804783060944 0.0010847138107705 0.0136099857954329 1254.707523799713 0.001143512283259 0.0137036668871313 1198.3838816383832 +r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 0.0052205259442072 0.0018452916334718 35.34685304110687 0.0085911211558188 0.0015329995362894 17.843998571142254 0.0234777578226843 0.0026533896684269 11.301716665052377 0.0391133977095598 0.0034503658296924 8.821442349021886 0.0428365307734951 0.0069640715401313 16.257319195513272 0.0593364683675767 0.006629716167228 11.173088573722188 0.0691322083053571 0.0108932693696886 15.757155219999646 0.0873769259750843 0.0165973939258096 18.99516804990648 0.0920948624104587 0.0151617995402077 16.46324142668555 +r_0066 4-amino-4-deoxychorismate synthase 1.2263986445948096e-05 0.0003131299707283 2553.247853856052 1.4113380092395228e-05 0.0003726720410535 2640.558382285616 2.5881997313567696e-05 0.0005896799040749 2278.3400250406103 4.212907014615767e-05 0.0009092194723594 2158.1759796859933 8.5686706790924e-05 0.0018772907323086 2190.8774448401405 7.677248028215486e-05 0.0014893336127046 1939.931609909006 0.0001491545662451 0.0031564667503202 2116.238764781004 0.0001988853762248 0.0045241214466507 2274.738109219151 0.0002381959299543 0.0048707162828595 2044.8360657517435 +r_0067 4-aminobenzoate synthase 1.2263986445948096e-05 0.0003131299707283 2553.247853856052 1.4113380092395228e-05 0.0003726720410535 2640.558382285616 2.588199731356769e-05 0.0005896799040749 2278.340025040611 4.212907014615767e-05 0.0009092194723594 2158.1759796859933 8.5686706790924e-05 0.0018772907323086 2190.8774448401405 7.677248028215486e-05 0.0014893336127046 1939.931609909006 0.0001491545662451 0.0031564667503202 2116.238764781005 0.0001988853762248 0.0045241214466507 2274.73810921915 0.0002381959299543 0.0048707162828595 2044.8360657517435 +r_0068 4-aminobutyrate transaminase 0.0002875024000065 0.005482092579086 1906.798892447733 0.0011233451122207 0.0125745238293711 1119.3820752478275 0.0008272919692358 0.0105225748519331 1271.9300130101851 0.0008772119933012 0.0123420446654301 1406.9625996541931 0.0011750274602619 0.0240228887099442 2044.4533870373352 0.0017979628312052 0.0232385359589288 1292.4925674548483 0.0021183091316912 0.0388316363544851 1833.14303722432 0.0029415860452364 0.0556225022877505 1890.901759539694 0.0034973171054996 0.0567931074336336 1623.905002618297 +r_0069 4-hydroxy-L-threonine synthase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0070 4-hydroxybenzoate formation 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0072 4-methyl-2-oxopentanoate decarboxylase 0.0002389146386893 0.0026474713880686 1108.124392289973 6.732741942938928e-05 0.0009230547204637 1370.9937619572866 0.0001748878432347 0.0022349665891392 1277.9427933933152 0.000240123104472 0.0027956105048829 1164.2405303022076 0.0005896128550789 0.0070593143742644 1197.279590065818 0.0005301530912791 0.0064958862043049 1225.2849811045392 0.000886994509111 0.0104920449728952 1182.8759778243357 0.0010750829947123 0.0144144317467499 1340.773858171451 0.0010578485872729 0.0139311092428789 1316.928472608026 +r_0073 4PP-IP5 depyrophosphorylation to IP6 -8e-13 2.8275782995003623e-11 -3534.472874375453 -1.6e-12 3.997198458808937e-11 -2498.2490367555856 -2.600000000000001e-12 5.092895788988829e-11 -1958.8060726880112 -4e-13 1.9997999499869665e-11 -4999.499874967415 -8e-13 6.633430521238259e-11 -8291.788151547826 -2e-13 2.4496530693205028e-11 -12248.265346602517 -3.000000000000001e-12 5.469550547955593e-11 -1823.183515985197 -1.8000000000000002e-12 4.6874294020157176e-11 -2604.1274455642874 -1.4e-12 3.739411269080566e-11 -2671.008049343261 +r_0074 4PP-IP5 pyrophosphorylation to 4,5-PP2-IP4 8e-13 2.8275782995003623e-11 3534.472874375453 1.6e-12 3.997198458808937e-11 2498.2490367555856 2.600000000000001e-12 5.092895788988829e-11 1958.8060726880112 4e-13 1.9997999499869665e-11 4999.499874967415 8e-13 6.633430521238259e-11 8291.788151547826 2e-13 2.4496530693205028e-11 12248.265346602517 3.000000000000001e-12 5.469550547955593e-11 1823.183515985197 1.8000000000000002e-12 4.6874294020157176e-11 2604.1274455642874 1.4e-12 3.739411269080566e-11 2671.008049343261 +r_0075 5'-methylthioadenosine phosphorylase 7.834207523224862e-05 0.000721967570452 921.5578835661316 0.0001164219440995 0.0011873339059774 1019.8540448376192 0.0001103091047917 0.0010053042362319 911.3520032004404 0.0001522751418464 0.0013893804234945 912.41446676538 0.000352811005793 0.0031487233305669 892.4674340840234 0.0003211544665833 0.0027870201590746 867.8129838032918 0.0004018975814094 0.0040787725506923 1014.8786007589928 0.0006911232925013 0.006750131082242 976.689854832082 0.0007068346038293 0.0066813847757115 945.2543409043672 +r_0076 5'-nucleotidase (CMP) 0.0001632215374921 0.0032194684484863 1972.453205595604 0.0002155064050915 0.0048449810797101 2248.184260533777 0.0001971167571028 0.0043592778759561 2211.5206946518188 0.0003397187038533 0.0069174591231549 2036.2314599377664 0.0004208760865596 0.0108704106462128 2582.805484405449 0.0004283945232976 0.0098305544122701 2294.743251290467 0.0009705003284644 0.0205524231964438 2117.714192736355 0.0011614084832891 0.0273547782154412 2355.310694646506 0.0010562146202998 0.025987880556036 2460.4734735312054 +r_0077 5'-nucleotidase (IMP) 0.0001648311274454 0.0032963193716878 1999.8160679804464 0.0003370719635874 0.0059856365631277 1775.7740808293945 0.00028063980976 0.0047288841626191 1685.0368330360177 0.0003938394214726 0.0070740592358591 1796.1785565819948 0.0008561128743774 0.0141247658401563 1649.8719109238025 0.0007294292070885 0.0130925520226003 1794.9037268273753 0.0010012684047988 0.0194631980959423 1943.8542155788457 0.0015372765250697 0.0297801418765614 1937.2013681930216 0.0017858320624769 0.0321539147157062 1800.5004720941415 +r_0078 5'-nucleotidase (UMP) 7.084977118306405e-05 0.0021071265145725 2974.076668685538 0.0002095519016414 0.0050511180823022 2410.4377210302 0.0001806295054146 0.0041665788792495 2306.6989358597075 0.0003914219553185 0.0073874488344308 1887.3363473999968 0.0007560362759511 0.0148662561849201 1966.341650235948 0.0004789673960899 0.0109503716613952 2286.245734216809 0.0009633580509735 0.0202666694539713 2103.7525386838274 0.0016061899445499 0.0324745302024732 2021.8362288136457 0.0015211837729328 0.0317812903993867 2089.247266825166 +r_0079 5'-phosphoribosylformyl glycinamidine synthetase 0.0023449246804801 0.0002829338294029 12.065796047016931 0.0038719214958873 0.0010230903188197 26.423322887782422 0.00886208077158 0.0008362145130136 9.435871039398544 0.0131844677905472 0.0013270928310142 10.065577557599688 0.0186309699037152 0.0024674059688484 13.243572297094316 0.0219398447660159 0.0011162616427227 5.08782835351583 0.0247854152299604 0.0039229085691191 15.827487789581795 0.0292495167731632 0.0061419597153137 20.99849978017101 0.0330699098225629 0.0059229816578712 17.91048626878961 +r_0080 5,10-methylenetetrahydrofolate reductase (NADPH) 0.0048207378741064 0.0023546125524186 48.84340559286489 0.0077573977167123 0.0029759163424293 38.36230203871261 0.0183829130773067 0.0038917311181013 21.170372191476247 0.0283767005075633 0.005616147068104 19.79140269182159 0.0374600828006425 0.0112898363591977 30.13831127731534 0.045802864556384 0.0088504869665649 19.32299879556634 0.0531996774842294 0.0174298030103502 32.76298623336037 0.0647366791203844 0.0258851639459521 39.98531326856615 0.0712448880090433 0.0254228752692324 35.68378866144824 +r_0081 5-aminolevulinate synthase 0.000111666174091 0.0011517148311508 1031.3909655504117 6.404717001076253e-05 0.0008480368071255 1324.0816213785174 0.0001153580141604 0.00134283872971 1164.0619331761263 0.0001114448779403 0.0016247479957375 1457.8938267644355 0.0003625825174417 0.0041041292660776 1131.9159277272877 0.0003087038247535 0.0037290410872725 1207.9672450605694 0.0003248540937801 0.0046597558536248 1434.4150013325 0.0007477574367461 0.008950356051309 1196.9598176457628 0.0007413068399591 0.0086513870396265 1167.045354674423 +r_0082 5-diphosphoinositol-1,2,3,4,6-pentakisphosphate diphosphohydrolase 7.382181020678226e-05 0.0023335162940197 3161.0120200024708 0.0001075054170453 0.0037997495351182 3534.472624309664 0.0001135407049946 0.0035890350286473 3161.011752406771 0.0001677274635513 0.00530188542972 3161.012107059065 0.0002009214116643 0.0082009411332767 4081.6660928986016 0.0002186795600244 0.007729179362534 3534.4772788406062 0.0004026622125018 0.0142319862123123 3534.4727591608766 0.0004583735513637 0.0187092780727636 4081.666146988915 0.0004403326917253 0.0179729102786911 4081.666116651181 +r_0083 5-diphosphoinositol-1,2,3,4,6-pentakisphosphate synthase 0.0001624070208467 0.0029486965440133 1815.621349766516 0.0002687636552014 0.0050214189336988 1868.3400216207308 0.0002497809583515 0.004535108530267 1815.6342101486173 0.0003373187787692 0.0064877037194344 1923.315311144407 0.0004685172411149 0.0105754690234925 2257.220886541004 0.0005196297787774 0.0100346918569861 1931.1233241087973 0.0010055073808718 0.0187925555429146 1868.9624661551663 0.0011458916578615 0.0247302995279762 2158.1708321473043 0.0010260900952638 0.0231659810848251 2257.6946402420026 +r_0084 5-formethyltetrahydrofolate cyclo-ligase -5.045831270379695e-10 1.6419258706100587e-09 -325.4024525648683 -2.0111658807764328e-10 2.211033333157341e-09 -1099.3788997174847 -2.014716887566354e-10 1.2950670711545987e-09 -642.8035021431497 7.096333101787122e-11 6.098549620335563e-10 859.3944975327781 1.186783542243182e-12 5.024603990471035e-10 42337.99856184265 -4.283539002912498e-10 9.739024690860855e-10 -227.3593093056704 -1.1292123500679931e-10 6.826379656916403e-10 -604.525770242007 -1.1662202023159652e-10 7.08228933655082e-10 -607.2857700875268 2.693715371527337e-10 6.382345591867916e-10 236.93466872296628 +r_0085 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0086 5-methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase 7.834208178750116e-05 0.0007219675433728 921.5577718896268 0.0001164219440995 0.0011873339059774 1019.8540448376192 0.0001103089926396 0.0010053042359157 911.3529294931504 0.0001522751418464 0.0013893804234945 912.41446676538 0.0003528110043817 0.0031487233307096 892.4674376942667 0.0003211544693242 0.0027870201415974 867.8129709548583 0.0004018975437401 0.004078772553986 1014.8786967016676 0.0006911232925013 0.006750131082242 976.689854832082 0.0007068345100315 0.0066813847647657 945.254464792284 +r_0087 5-methylthioribose-1-phosphate isomerase 7.834207523224862e-05 0.000721967570452 921.5578835661316 0.0001164219440995 0.0011873339059774 1019.8540448376192 0.0001103091047917 0.0010053042362319 911.3520032004404 0.0001522751418464 0.0013893804234945 912.41446676538 0.000352811005793 0.0031487233305669 892.4674340840234 0.0003211544665833 0.0027870201590746 867.8129838032918 0.0004018975814094 0.0040787725506923 1014.8786007589928 0.0006911232925013 0.006750131082242 976.689854832082 0.0007068346038293 0.0066813847757115 945.2543409043672 +r_0088 5PP-IP5 pyrophosphorylation to 4,5-PP2-IP4 -8e-13 2.8275782995003623e-11 -3534.472874375453 -1.6e-12 3.997198458808937e-11 -2498.2490367555856 -2.600000000000001e-12 5.092895788988829e-11 -1958.8060726880112 -4e-13 1.9997999499869665e-11 -4999.499874967415 -8e-13 6.633430521238259e-11 -8291.788151547826 -2e-13 2.4496530693205028e-11 -12248.265346602517 -3.000000000000001e-12 5.469550547955593e-11 -1823.183515985197 -1.8000000000000002e-12 4.6874294020157176e-11 -2604.1274455642874 -1.4e-12 3.739411269080566e-11 -2671.008049343261 +r_0089 5PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 8.858521143995052e-05 0.0018062654261654 2039.0146355182817 0.000161258239756 0.0032880436468555 2038.9926442389008 0.0001362402559568 0.0027779454535734 2039.0048697895188 0.000169591315618 0.0037466267759096 2209.209099096 0.0002675958302506 0.0066852571357479 2498.266557250018 0.000300950218953 0.0064098734018296 2129.878298188119 0.00060284517137 0.0122921233292578 2039.0182940874947 0.0006875181082978 0.0161920053102537 2355.1387395951792 0.0005857574049384 0.014633971985621 2498.2991016831497 +r_0090 6-phosphofructo-2-kinase 7.382183548526486e-05 0.0023335172576131 3161.012242887013 0.0001611478003615 0.0046496147485423 2885.310713588262 0.0001111116296385 0.0035155281259252 3163.9605479304428 0.0001341822281825 0.0047426274873301 3534.467679934891 0.0004662136283517 0.0124537696954644 2671.25818254064 0.0002180945049973 0.0077085711748503 3534.509581039118 0.0004024794814691 0.0142255274617098 3534.472716418716 0.0006086989154063 0.021514518382877 3534.509071453529 0.0008744987248871 0.02523507218577 2885.661404369298 +r_0091 6-phosphogluconolactonase 0.1518164689461646 0.1222602222465491 80.53159390099083 0.3113446561747209 0.2398666904557582 77.04217358436031 0.6569314824571103 0.313077605260402 47.65757367715167 1.101905159452342 0.5437055418259025 49.34231745462827 1.585118138396738 0.9339281380816592 58.918519412457 1.4342438461206886 0.7857949735030078 54.78810145348776 1.980301841238367 1.1104391932515116 56.07423929662696 2.41341223802261 1.6243106426608889 67.30348910436209 3.0034807398142847 1.2410592511387946 41.320699503321386 +r_0092 6PP-IP5 depyrophosphorylation to IP6 -3.4540000000000963e-10 4.993482850095245e-10 -144.57101476824286 -2.8580000000000505e-10 4.896593849429114e-10 -171.32938591424164 -2.4960000000000243e-10 4.789005211333851e-10 -191.8671959668992 -3.488000000000097e-10 5.003884868055671e-10 -143.46000195113334 -2.702000000000039e-10 4.758542292020631e-10 -176.11185388677137 -3.816000000000122e-10 5.150092104976431e-10 -134.96048493124383 -3.8500000000001237e-10 5.422488421023395e-10 -140.8438550915122 -4.926000000000204e-10 5.215358472127987e-10 -105.8741062145304 -7.700000000000047e-11 6.362011870392036e-10 -826.2353078431166 +r_0093 6PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 3.4540000000000963e-10 4.993482850095245e-10 144.57101476824286 2.8580000000000505e-10 4.896593849429114e-10 171.32938591424164 2.4960000000000243e-10 4.789005211333851e-10 191.8671959668992 3.488000000000097e-10 5.003884868055671e-10 143.46000195113334 2.702000000000039e-10 4.758542292020631e-10 176.11185388677137 3.816000000000122e-10 5.150092104976431e-10 134.96048493124383 3.8500000000001237e-10 5.422488421023395e-10 140.8438550915122 4.926000000000204e-10 5.215358472127987e-10 105.8741062145304 7.700000000000047e-11 6.362011870392036e-10 826.2353078431166 +r_0094 8-amino-7-oxononanoate synthase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0095 acetaldehyde condensation 6.788207824874526e-05 0.0016072733986043 2367.7433574067286 1.3037701081597216e-05 0.0005321529631798 4081.647215635002 4.061370215497746e-05 0.00150784750222 3712.657113764818 1.1057426738133638e-05 0.0007818730934251 7071.02214594577 0.000149708394834 0.0052914035965172 3534.4735359587453 0.0002859659195328 0.0063928612229878 2235.5325534703 0.0003220436500992 0.0084122300919915 2612.1397175193565 0.0004335966557518 0.0137060442020763 3161.012434081468 0.0003332247535068 0.0117777395350745 3534.473177975472 +r_0096 acetohydroxy acid isomeroreductase 0.0107042011860401 0.0054521806847415 50.93496086239531 0.017038841981713 0.001809182664447 10.6179907436714 0.0472308611598065 0.0052947606338007 11.210383431049037 0.0787232911788867 0.0052837183930985 6.711760031846299 0.0856945528232948 0.0134012568786366 15.63839991821946 0.1198004584666212 0.0147937029547767 12.348619649814289 0.1389759458806026 0.0208945916223406 15.034682073897674 0.1755822184838486 0.0323130094026046 18.40334954281096 0.1851432176234126 0.0301630519585001 16.29174017049483 +r_0097 acetolactate synthase 0.0107042011860401 0.0054521806847415 50.93496086239531 0.017038841981713 0.001809182664447 10.6179907436714 0.0472308611598065 0.0052947606338007 11.210383431049031 0.0787232911788867 0.0052837183930985 6.711760031846299 0.0856945528232948 0.0134012568786366 15.63839991821946 0.1198004584666212 0.0147937029547767 12.348619649814289 0.1389759458806026 0.0208945916223406 15.034682073897674 0.1755822184838486 0.0323130094026046 18.40334954281096 0.1851432176234126 0.0301630519585001 16.29174017049483 +r_0099 acetyl-CoA ACP transacylase -2.802000000000047e-10 5.408756504908305e-10 -193.0319951787372 9.687999999999692e-10 2.1595343752168477e-10 22.29081725038106 9.63999999999971e-10 2.5281768798220313e-10 26.22590124296792 9.619999999999712e-10 2.5013698987303337e-10 26.00176609906869 9.6539999999997e-10 2.379373086183908e-10 24.64649975330413 -1.2939999999999988e-10 5.233645212320348e-10 -404.4548077527321 9.657999999999703e-10 2.3117319959209077e-10 23.935928721484565 7.672000000000393e-10 5.822988703362372e-10 75.89922710325958 9.649999999999703e-10 2.3871823826314824e-10 24.73764127079332 +r_0100 acetyl-CoA C-acyltransferase (palmitoyl-CoA) 0.0001025024239969 0.0012895752229371 1258.0924164049393 0.0003573695226564 0.0026794028694519 749.7569601166206 0.0001665343971771 0.0019514240551907 1171.784381046173 0.0003293663836064 0.0031923104322111 969.2277630935588 0.0004237154405185 0.0055561900637527 1311.3022402375566 0.0007414198762234 0.0060338977601897 813.830051458104 0.0006563466998531 0.0086081859745324 1311.5303202496368 0.0014369306208613 0.0130282706767201 906.673606058336 0.0009537961458257 0.0125450413920101 1315.2749093098205 +r_0101 acetyl-CoA C-acyltransferase (tetracosanoyl-CoA) 1.381266232907092e-05 0.0002438143307489 1765.150880694785 2.767369243194784e-05 0.0004623747455663 1670.809729143942 1.7541270215761327e-05 0.0003355518289557 1912.927768789616 2.316955401511373e-05 0.0004727535056088 2040.408310408104 8.784776950264994e-05 0.0013020270640894 1482.1401516064416 3.232701663934004e-05 0.0007166373909397 2216.837386929269 8.24977939226892e-05 0.0015569141018982 1887.219073224246 0.0001942155135057 0.0029075155511991 1497.0562849052542 0.0001976033366663 0.0029069834573947 1471.1206331007252 +r_0102 acetyl-CoA C-acyltransferase (myristoyl-CoA) 0.0001559164264157 0.0012768663523271 818.9428026798172 0.0003322785952227 0.0026546755805372 798.9306620120234 0.0002868750321416 0.0022804643321424 794.9330114641144 0.0004029261164038 0.0032301075260934 801.6624871383468 0.000716445893011 0.0059338468524374 828.2337731742747 0.0005799308198707 0.0035762477925967 616.6680007442345 0.0009804443320349 0.0083419646772849 850.835116764948 0.0012734640400243 0.0083562510647379 656.1827269640066 0.0015135328112166 0.0122616029038455 810.1312910414581 +r_0103 acetyl-CoA C-acetyltransferase -2.731389882307754e-05 0.0004676529810069 -1712.142905837652 -8.666866933130543e-05 0.0011166506202615 -1288.4132511519038 -4.823662481517195e-05 0.0007684677918265 -1593.1209838397497 -6.887845863366371e-05 0.0010897307814621 -1582.106805348224 -0.0001474522368334 0.0023270696837099 -1578.1854068025614 -0.0001267515040575 0.0019518835506491 -1539.9293011641475 -0.00022684873779 0.0035174237627761 -1550.5591069377233 -0.0003658476614357 0.0054871424245156 -1499.843514915845 -0.0003497131130438 0.0052771460407827 -1508.9928984507596 +r_0104 acetyl-CoA C-acetyltransferase 0.0053001906425731 0.0018711292447856 35.3030555119294 0.0083367862376668 0.0011828775915692 14.188652051852454 0.0192965990029422 0.0020484506360708 10.615604520561078 0.0286193723832947 0.0026701614973804 9.329909341195169 0.0407809096081129 0.0061833091913512 15.162264036702927 0.0480584479079542 0.0057014975449106 11.863673907718889 0.054291012339274 0.0101436805442741 18.683903849286303 0.0639823804577732 0.0129443223471626 20.23107339012736 0.0724009683014875 0.0141460310987399 19.538455673457204 +r_0105 acetyl-CoA C-acyltransferase (lauroyl-CoA) 0.0002090015703217 0.0015207981593946 727.6491545272543 0.0003197672980343 0.0019236525924125 601.5788994801907 0.0003104013245283 0.0023440650718287 755.1723805915781 0.0004377289124604 0.0032684849624291 746.6915868218442 0.0008817518618033 0.0062527347672168 709.1263470007252 0.0007309436712479 0.0039635473219108 542.2507202427232 0.0015390036007872 0.0102683117637413 667.2051812281993 0.0029030280405835 0.0184364688049741 635.077186552704 0.0023280656738822 0.0165320779539908 710.1207727710853 +r_0106 acetyl-CoA C-acyltransferase (octanoyl-CoA) 7.324981212949178e-05 0.0004543895307149 620.3285953986 0.0001257654615904 0.0007499685345547 596.3231280434618 0.000101396559069 0.0006318598172779 623.1570608305915 0.0001680019892753 0.0009835494748556 585.4391838442133 0.0003563107362173 0.0020442921917206 573.7385893624482 0.0002598844908445 0.0016370128575299 629.9001730384804 0.0004830437403873 0.0029073391154787 601.8790582293072 0.0007391095702217 0.0044526170831537 602.4299051922709 0.0007283251562383 0.0043061248748595 591.2365978267305 +r_0107 acetyl-CoA C-acyltransferase (decanoyl-CoA) 6.836678222914591e-05 0.0004409538380122 644.9825831122599 0.0001194252007976 0.0007190288659199 602.0746551964049 9.469091772734848e-05 0.0006095527072082 643.7287987464235 0.0001528445142784 0.0009341997118306 611.2091861725415 0.0003087015584464 0.0018988785402391 615.1178989167296 0.0002681626928161 0.0016730504551704 623.8938152061072 0.0004613745539486 0.0028427908333229 616.1568315792962 0.0006697757169914 0.0042299666507877 631.5497178351599 0.0006490065439105 0.0040739857434687 627.7264507875656 +r_0108 acetyl-Coa carboxylase -7.600000000000002e-12 9.769415965024004e-11 -1285.4494690821057 -9.000000000000004e-12 9.444990289476612e-11 -1049.443365497401 -7.000000000000001e-12 9.875702805430514e-11 -1410.8146864900732 -3.8e-12 8.115957969010801e-11 -2135.7784128975795 -5.999999999999998e-12 8.925017153274383e-11 -1487.5028588790644 -1.6e-12 6.927048202471001e-11 -4329.405126544376 -1.0400000000000007e-11 1.1087965935992347e-10 -1066.1505707684942 -1.0200000000000007e-11 1.1357173815673423e-10 -1113.4484133013152 -1.4e-12 7.070388820963914e-11 -5050.2777292599385 +r_0109 acetyl-CoA carboxylase, reaction 0.028255259107659 0.0050248690814705 17.783836496861 0.0461233358720121 0.0079607274679016 17.259652445763933 0.1035883306251288 0.0068653122036853 6.627495744216478 0.1541673981963822 0.0103945491696801 6.742378279251596 0.2188072129896074 0.0205442718800607 9.389211442968552 0.2580792134408745 0.0184819324523517 7.161340971998081 0.2915761455478089 0.0311093014757382 10.669357542020636 0.3458858031374142 0.0479920877637714 13.875125063952115 0.3889955234093772 0.0450263700298055 11.57503552615952 +r_0111 acetyl-CoA hydrolase 7.788769900988683e-06 0.0005507259939513 7070.76985136583 4.677742493845427e-05 0.0023644777843925 5054.741229350621 3.84404594802043e-05 0.0019532267918667 5081.174414350029 2.6570268414917274e-05 0.0018787517295461 7070.879752540797 0.0002609193711608 0.0092320151700895 3538.26361339748 0.0001024656806177 0.0051346345005438 5011.07733788478 0.0002152527364904 0.0089890946954756 4176.065234773554 0.0004513977719723 0.0184289526096051 4082.64146477338 0.0005801344758152 0.0205091460568744 3535.240002424381 +r_0112 acetyl-CoA synthetase 0.0349033044039854 0.0066147410522129 18.951618378739084 0.0568839682710498 0.0110040315906506 19.34469750460609 0.1286917364368095 0.0089568454423678 6.959922750569032 0.193043949295274 0.0147183231175833 7.624337966206141 0.2700664130935754 0.0275539896006244 10.202671737294931 0.3210657496084357 0.0243963148430491 7.598541692099617 0.3637787723525035 0.0423375954547033 11.63828092027262 0.4325310684365711 0.0643487533470748 14.877255772555284 0.484517951914918 0.0607319532515334 12.534510436921458 +r_0113 acetyl-CoA synthetase 0.0002229130243767 0.0038743719257398 1738.064402729297 0.0004901813428751 0.0077904110318309 1589.2916254494824 0.0002901849964798 0.0054809077212743 1888.763301949414 0.0004029554578299 0.0079727493403037 1978.5683964274035 0.0010139963520198 0.0174096119445016 1716.9304317339784 0.0008555615090751 0.0145956569833268 1705.9740098761558 0.0012640669917765 0.0248395135996378 1965.0472452198208 0.00278719888956 0.0442603268682795 1587.9859537137522 0.0020932291604686 0.0373839416241199 1785.9459599611732 +r_0114 acetyl-CoA synthetase nuclear 5.791478400000231e-10 1.216295606922934e-09 210.01470141421672 9.60550319954133e-10 1.6271388989684935e-09 169.39652875720145 7.980927992625757e-10 5.36181717842161e-10 67.18287877519809 9.25599999999984e-10 3.0932794370272143e-10 33.41918147177255 4.18925284342546e-10 8.56756078739542e-10 204.51285963417564 9.3759519999998e-10 3.4202499142007594e-10 36.4789614345384 9.540817999999742e-10 2.696010238318228e-10 28.257642461247045 8.976251999999934e-10 4.43158510939519e-10 49.370105801343605 9.124193999999887e-10 3.7189834898805926e-10 40.75958369452293 +r_0115 acetylglutamate kinase 0.00312440564599 0.0019966514679592 63.90500127669979 0.0054746023696121 0.0043834382708851 80.06861457585043 0.0143499339320211 0.0048554362609746 33.83594854147704 0.0239043309399121 0.0078884097520724 32.99991860011232 0.026335567712415 0.013354293090009 50.70820282227532 0.0359540102750602 0.0108149342641162 30.07991092336671 0.0424240185469133 0.0203082133598037 47.86961267553304 0.0537932526431609 0.026649939197222 49.541416233008114 0.0568555534385222 0.026923313794912 47.35388570972949 +r_0116 acid phosphatase (secreted) 6.992992000000396e-10 4.779900883745159e-10 68.35272918580326 4.89298200000034e-10 5.191213448423111e-10 106.09508574572216 6.259998000000318e-10 5.489846331414393e-10 87.69725375973144 6.606998000000354e-10 5.039602858101918e-10 76.27674260082486 2.5800000000000304e-10 5.584786295606229e-10 216.46458510101408 2.386000000000016e-10 5.597612942507845e-10 234.60238652589305 6.114000000000293e-10 5.696094547900408e-10 93.16477834314904 5.104000000000217e-10 6.330655530029114e-10 124.03321963222656 5.116000000000221e-10 5.881620753885782e-10 114.96522192895875 +r_0117 aconitase 1.40758437259623e-05 0.0004448215083064 3160.1765191950544 0.0001412729342032 0.001538134785996 1088.768202253905 9.688439548988284e-05 0.0015171922548135 1565.9820625829648 0.0001382676929956 0.0021501463748862 1555.0605700451931 0.0002789801104243 0.0040299106045713 1444.5153808428015 0.000140783099587 0.0025941983339369 1842.6915883692525 0.0003923802770424 0.0058898748220155 1501.0629143773308 0.00048450121511 0.0077971879661726 1609.3226854758857 0.000519284440575 0.0079842360214296 1537.5457836919152 +r_0118 acteylornithine transaminase 0.00312440564599 0.0019966514679592 63.90500127669979 0.0054746023696121 0.0043834382708851 80.06861457585043 0.0143499339320211 0.0048554362609746 33.83594854147704 0.0239043309399121 0.0078884097520724 32.99991860011232 0.026335567712415 0.013354293090009 50.70820282227532 0.0359540102750602 0.0108149342641162 30.07991092336671 0.0424240185469133 0.0203082133598037 47.86961267553304 0.0537932526431609 0.026649939197222 49.541416233008114 0.0568555534385222 0.026923313794912 47.35388570972949 +r_0119 acyl carrier protein synthase 5.670629908253708e-05 0.0010281356848227 1813.0890244244545 0.0001949844769379 0.0023584902281762 1209.5784573285223 6.035675948030135e-05 0.0012811191233825 2122.5777102905563 0.0001566707941741 0.0023093454106142 1474.011428094997 0.0002719355356448 0.004730757659667 1739.6614416167015 0.0001892708227335 0.0036235187074871 1914.462385250448 0.0005297792297927 0.0081481753936131 1538.0322472817918 0.0007991506328638 0.0126607997106198 1584.2820101698462 0.0007247570069044 0.0116590330991631 1608.6816668335168 +r_0120 acyl-CoA oxidase (decanoyl-CoA) 5.436226415948966e-05 0.0003889328185172 715.4463202197744 0.0001096659250968 0.0006982903669149 636.7432420767697 8.799231390692818e-05 0.0005879773924287 668.2144909277956 0.0001399663299479 0.0008975779054292 641.2813036984991 0.0002823237490685 0.0018204702766728 644.8165564105212 0.0002077849885509 0.001456652219011 701.0382362892027 0.0004173434354081 0.0027038368444134 647.8685454268696 0.0006033807778061 0.0040259581880588 667.2334181239054 0.0005969886489198 0.0039124349472361 655.3616981352957 +r_0121 acyl-CoA oxidase (dodecanoyl-CoA) 6.365415500478824e-05 0.0004271518626353 671.0510297453293 0.0001017920952741 0.0006667581340349 655.0195594651876 8.511906110304275e-05 0.0005817174147847 683.4161552611251 0.0001379121541949 0.0008925485320258 647.1862739263532 0.0002853373000337 0.0018352798643808 643.1966182353003 0.0002369492824737 0.0015824579053252 667.8466753748428 0.0004156200271722 0.0027138602673453 652.96667386544 0.000593711002888 0.0040144460529005 676.1616398167494 0.0005771996870246 0.0038660839916162 669.8000845331995 +r_0122 acyl-CoA oxidase (hexacosanoyl-CoA) 1.3812669458690668e-05 0.0002438143303445 1765.1499666569475 2.767369243194784e-05 0.0004623747455663 1670.809729143942 1.7541250426333123e-05 0.0003355518299853 1912.929932758109 2.316955401511373e-05 0.0004727535056088 2040.408310408104 8.784776950264994e-05 0.0013020270640894 1482.1401516064416 3.2327083047663246e-05 0.00071663738794 2216.832823683547 8.249779330855514e-05 0.0015569141019306 1887.2190873125348 0.0001942154103862 0.0029075155580871 1497.057083320273 0.0001976033366663 0.0029069834573947 1471.1206331007252 +r_0123 acyl-CoA oxidase (hexadecanoyl-CoA) 0.0001559164308351 0.0012768663517871 818.9427791205857 0.0003322785952227 0.0026546755805372 798.9306620120234 0.0002868750321416 0.0022804643321424 794.9330114641144 0.0004029261164038 0.0032301075260934 801.6624871383468 0.0007164459010611 0.0059338468514651 828.2337637323795 0.0005799308112957 0.0035762477939876 616.668010102311 0.0009804443317306 0.0083419646773206 850.835117032691 0.0012734640400243 0.0083562510647379 656.1827269640066 0.0015135328000041 0.0122616029052298 810.1312971345174 +r_0124 acyl-CoA oxidase (octadecanoyl-CoA) 0.0001025024243621 0.001289575222908 1258.0924118939963 0.0003573695115738 0.0026794028709301 749.7569837814256 0.0001665343803856 0.0019514240566238 1171.784500056045 0.0003293663836564 0.003192310432206 969.2277629448696 0.0004237154405185 0.0055561900637527 1311.3022402375566 0.0007414198809147 0.0060338977596133 813.830046230815 0.0006563466980532 0.0086081859746696 1311.5303238672009 0.0014369306361332 0.0130282706750348 906.6735963048228 0.0009537961407361 0.0125450413923975 1315.2749163689932 +r_0125 acyl-CoA oxidase (tetradecanoyl-CoA) 0.0001695077078489 0.0014554572117321 858.6377753565248 0.0002563718762805 0.0017680517499128 689.6434100198464 0.0002488591424649 0.0022427574290194 901.2156060671476 0.0003411330434379 0.0030961645355812 907.6120285441422 0.000677938627824 0.0058715450822313 866.0879969440925 0.0005620719774095 0.0035471281427323 631.0807663957834 0.0011434100237126 0.0095917314911016 838.8706843724331 0.0024816933605087 0.0178549546874578 719.4665937212196 0.0018883620034904 0.0158612350704819 839.9467390873289 +r_0126 acyl-CoA:sterol acyltransferase (oleoyl-CoA:episterol), ER membrane 7.415767077801203e-05 0.0017636932814064 2378.301884219129 0.0001034006784694 0.0028099253797364 2717.5115495666664 0.0001002778583525 0.0025543237634148 2547.246027566457 0.0001391189462706 0.0037162589674149 2671.2817103899542 0.0004803452480591 0.0097669295378184 2033.3144914585484 0.0001310795849578 0.0046029470509269 3511.566696223824 0.0007453336972544 0.0146503610792965 1965.6109918636364 0.000732688444646 0.0183044270617905 2498.255185480983 0.0008330121449318 0.0186748364813758 2241.8444430846766 +r_0127 acyl-CoA:sterol acyltransferase (oleoyl-CoA:ergosterol), ER membrane 0.0002725433011002 0.0013778676542098 505.55917120233056 0.0005051344721764 0.0032180744463108 637.0728238849571 0.0010043321423107 0.0030393608392113 302.6250690551855 0.0014937855638444 0.0044716338201987 299.34911197631504 0.0019871390715305 0.0056904378394907 286.36334119825005 0.0024803510143907 0.0073008084828634 294.3457776945692 0.0030164578605015 0.0132823799184438 440.3303653721715 0.0035711036366269 0.0182568303458322 511.2377629868181 0.00454283010722 0.0239799796377725 527.8643284427617 +r_0128 acyl-CoA:sterol acyltransferase (oleoyl-CoA:fecosterol), ER membrane 0.0001038469476735 0.0021233181549142 2044.661111840441 9.675748787365056e-05 0.002787403071106 2880.8138081736643 0.0001255976903768 0.0028447376874913 2264.9601907139013 0.000188660345386 0.0042735919825546 2265.2306576718183 0.0004222018628428 0.0090623760972143 2146.4557347506084 0.0004785424369088 0.0087469959939627 1827.841236080048 0.0004636516303708 0.0116076645151715 2503.5314781244983 0.001092418078011 0.0222789923957112 2039.419966051384 0.0009425561955266 0.0201346791853456 2136.178116583753 +r_0129 acyl-CoA:sterol acyltransferase (oleoyl-CoA:lanosterol), ER membrane 3.905073421176902e-05 0.0012514750584958 3204.7414312601013 2.6982761487692364e-05 0.0013627110953662 5050.302564427507 0.0001050110661788 0.0026276965581214 2502.3044272734824 9.977060161753292e-05 0.0031540345334483 3161.286473483629 0.0002257660440586 0.0065753554787498 2912.464319498059 0.0001969804492059 0.0054011399090714 2741.967505325126 0.0002362875366101 0.0083568459089561 3536.7273402766104 0.0009667592508648 0.0206425997820803 2135.2368507063948 0.0006718996140615 0.0169050217975301 2516.004094025472 +r_0130 acyl-CoA:sterol acyltransferase (oleoyl-CoA:zymosterol), ER membrane 0.000192345794868 0.0028905529286807 1502.7897701968411 0.0002958408314679 0.0048329986991038 1633.6482949711258 0.0002695103570956 0.0042033984323118 1559.6426340008509 0.0003651980683647 0.0059438914717508 1627.58020554889 0.0003077528809633 0.0075948139502844 2467.8287093561 0.0004453349519556 0.0084281845395542 1892.5495298636413 0.0014216156576181 0.0201919200639659 1420.3501456783324 0.0009851669032263 0.0210279550796064 2134.456101878854 0.0015825266791759 0.0256855551141168 1623.0724860507476 +r_0131 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:episterol), ER membrane 6.12542884670779e-05 0.0016345407543816 2668.451132625893 0.000181431272598 0.0037164928632125 2048.430135550658 3.562393734349769e-05 0.0011020081614684 3093.4485170533894 8.054447527686717e-05 0.0027884615161249 3462.0146279924697 0.0002794329113225 0.0074636176861472 2670.9873403319107 0.0002827460934592 0.0066850500057007 2364.329750381912 0.00031391389891 0.0095628179139617 3046.318734902932 0.0005966647738017 0.0160383993704462 2688.0084219241744 0.0002663397850331 0.0107843948385498 4049.111490124138 +r_0132 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane 4.945816498058475e-05 0.0013844844601046 2799.3041404753167 0.000118319009792 0.0030039828016644 2538.884332232732 3.592583852785965e-05 0.0007801897030758 2171.667343187668 0.0001079115079472 0.0028258418211972 2618.665863309947 0.0004347585001935 0.0088509573782415 2035.8330830339423 0.0002829382746482 0.0060127435813725 2125.1078839891607 0.0002417725890724 0.007414212138439 3066.605758280816 0.0007020400723653 0.0171435066417961 2441.9555687233456 0.0003319844879172 0.0107936696969356 3251.257239352577 +r_0133 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:fecosterol), ER membrane 4.3564807042056615e-05 0.0013735412962469 3152.8690002482163 0.0001130142760364 0.0029683935421234 2626.5651086110543 1.84243965607458e-05 0.0007745075002791 4203.706198602171 0.0001698243289541 0.0039356603990826 2317.4891508888168 0.0002407849377678 0.0069474143476611 2885.319327723136 0.0001563461684382 0.0045908405198505 2936.3306857530533 0.0004109278705395 0.0108903247477675 2650.1791502893907 0.0006232507790964 0.0166400822716372 2669.8855147459203 0.0012696440987731 0.0232118761901975 1828.2191216126864 +r_0134 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:lanosterol), ER membrane 3.562117035113186e-05 0.0012524496556142 3516.0261251058832 9.05970816526504e-05 0.002626589517923 2899.198815248114 4.85869586147664e-05 0.0013301470670279 2737.662749328167 7.172826889310283e-05 0.0025738171128522 3588.288345126514 0.0002575267098863 0.0068509701521838 2660.294986569096 0.0003416660914448 0.0072279926838916 2115.51361544997 0.0005299797903891 0.0121783012768547 2297.8803150044632 0.0012562014686489 0.0237343962371072 1889.378163411473 0.0005306306942419 0.0152409601085457 2872.234922316067 +r_0135 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:zymosterol), ER membrane 0.000123955192501 0.002337244006872 1885.5555460910305 0.000418008038709 0.005702956686037 1364.3174671114016 0.0002230588993051 0.0037467717892054 1679.72306905317 0.000464523196741 0.0066959507275041 1441.4674605016298 0.0006756253315183 0.01156654360541 1711.9760118254767 0.0006170789227343 0.0099917905074231 1619.2078742778235 0.0010022572579476 0.0169713905461421 1693.316801805399 0.0019392390112724 0.0292588057659831 1508.777700732476 0.0007322060245748 0.017463484772515 2385.0506805998057 +r_0137 acylation of GPI inositol at 2 position, GPI-anchor assembly, step 3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0138 adenine deaminase 2.70428922936744e-05 0.0009329738977979 3449.978233342378 5.985279006765343e-05 0.0018906704049192 3158.8676196751144 5.3816264336636375e-05 0.0017008045164705 3160.3912635621045 9.532075456193976e-05 0.0027500617881764 2885.060867189636 0.0002154566305124 0.0057545201184303 2670.8484694776184 0.0001032919859602 0.0036506784811383 3534.32887091927 0.0005060543446611 0.0107778355023993 2129.7782769983337 0.000282485806254 0.0097161365768906 3439.5131938597538 0.0004670381427723 0.0124735365317801 2670.7746947038863 +r_0139 adenine phosphoribosyltransferase 3.0861171515916e-05 0.00113334119813 3672.385533211524 7.312433941122691e-05 0.0023703703808364 3241.561428003124 7.890936966718861e-05 0.0021596320792133 2736.851261544637 0.000127078076895 0.0032521047707849 2559.139113720578 0.0002883122422377 0.0069008057335107 2393.518110763884 0.0001570706157548 0.0046103568136625 2935.2127968090053 0.0003248880552572 0.0092234257133103 2838.955007442916 0.0005818577925006 0.0153527884242428 2638.580873560226 0.0006879591198977 0.0162272269465335 2358.748721718482 +r_0140 adenosine deaminase 1.3201571629443227e-05 0.0006598952496403 4998.61128783016 3.790147933734693e-05 0.0014657848090828 3867.35513945636 3.2232813472891416e-05 0.00131562663872 4081.637613876127 3.539511136851357e-05 0.0016103994343338 4549.779255014415 6.17318969142138e-05 0.0030862654016294 4999.466330863428 8.39763181229875e-05 0.0032110351758994 3823.73893934804 0.0001055169832047 0.0046499721675949 4406.847150447897 0.0002064988324425 0.0084285714857826 4081.6557585764 0.0001425001163371 0.006702297518431 4703.36283977023 +r_0142 adenosine kinase 0.0037146411737751 0.0027929402539295 75.18734982122409 0.0058554259020562 0.0035560176149587 60.73029826421278 0.0129289503795516 0.0046730508410035 36.14408520272808 0.0190870573420779 0.006240311901651 32.69394432998376 0.0278068175220465 0.014291523007477 51.3957521249819 0.0320379159397365 0.0120309554766656 37.55224122347996 0.0373637453360377 0.0215653373386461 57.717279530449225 0.0453773925001341 0.0344286297181085 75.87176746219326 0.0507936749955093 0.0353530309438848 69.60124650758259 +r_0143 adenosine monophosphate deaminase 9.841447975625643e-05 0.002318385869789 2355.73654967334 9.811797171178868e-05 0.0031032989028088 3162.8241479802014 8.514234717249627e-05 0.0026913502303536 3161.0007472556927 0.0001716603693274 0.0045908057383472 2674.3538746501845 0.0001997592796128 0.0070607673424731 3534.637968336692 0.0001171354852776 0.0047935192367547 4092.2861465862 0.0004451624815956 0.0128511792085197 2886.85137221246 0.0004583297964613 0.0161995215643784 3534.468343418333 0.000330223934888 0.013478623751725 4081.661662802988 +r_0144 adenosylhomocysteinase 0.0036311420792481 0.0024962460757562 68.74548065806275 0.0057598335571367 0.0033506165701537 58.17210752561057 0.0128442148563562 0.0042158477611894 32.822930855156066 0.0190194026393929 0.0059697644742569 31.387760107104263 0.0274650369071511 0.0121481646714913 44.23137938084581 0.0316282353353437 0.0090907521425084 28.742520871373944 0.0369553792282168 0.0185223688951672 50.12090061580191 0.04443048672252 0.0281336417779664 63.320579748919606 0.0497744668615826 0.0278030119987538 55.85798051051156 +r_0145 adenosylmethionine decarboxylase 7.834207523224862e-05 0.000721967570452 921.5578835661316 0.0001164219440995 0.0011873339059774 1019.8540448376192 0.0001103091047917 0.0010053042362319 911.3520032004404 0.0001522751418464 0.0013893804234945 912.41446676538 0.000352811005793 0.0031487233305669 892.4674340840236 0.0003211544665833 0.0027870201590746 867.8129838032918 0.0004018975814094 0.0040787725506923 1014.8786007589928 0.0006911232925013 0.006750131082242 976.689854832082 0.0007068346038293 0.0066813847757115 945.2543409043672 +r_0146 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0147 adenylate cyclase 8.858605837695744e-05 0.0019790605639627 2234.054206973842 0.0001773820592405 0.0037780137637164 2129.873663600516 0.0001497681075375 0.0031898794251032 2129.8789692609976 0.0002414662373018 0.0049234847955439 2038.995120211691 0.0003212528820033 0.0080257094175405 2498.252892703244 0.0003608862236308 0.0076864423668144 2129.8796860356847 0.0005435004708994 0.0128001759502525 2355.136128781926 0.0008250617180921 0.0194313243500104 2355.135855162714 0.0007041409699226 0.0175912140603283 2498.251743860483 +r_0148 adenylate kinase 0.1292415554287214 0.015962648989722 12.351018940286322 0.2169764974308249 0.0287834804343736 13.26571346445034 0.5365961454983302 0.0245770788532277 4.580181773464536 0.8686514355867037 0.0367241952803146 4.2277251583093785 1.0317811188265515 0.0723777144139839 7.0148322249102 1.349027410013718 0.0584693797946663 4.334187679260855 1.573786267150697 0.10912597520823 6.933976835736411 1.9593936967280725 0.1649929814387859 8.420614076400385 2.1023707688667463 0.1596198106219896 7.592372049009722 +r_0149 adenylate kinase 0.0001823114365899 0.0034976709389875 1918.5142766743825 0.0003020478118604 0.0061856267079001 2047.8965465105728 0.0001540102907522 0.0040711384144421 2643.4197316009845 0.0002855540884299 0.0067866959645592 2376.6761673331066 0.0004950637124498 0.0122935168844344 2483.219144380217 0.0004290454869466 0.0105641055415463 2462.234393077124 0.0008865750641619 0.0209107508837343 2358.599032277074 0.001413825399688 0.0316814171317052 2240.8295351530937 0.0008863300086586 0.0247930612759302 2797.2720131017286 +r_0150 adenylate kinase (GTP) 4.060199003836773e-05 0.0016708865542638 4115.2824102585455 0.0001881344471164 0.0047478612608827 2523.653341349594 0.000136177688968 0.0036753409289267 2698.9303143411216 0.0001174096095995 0.0041919625975503 3570.374360198352 0.0005189419664626 0.0123481955655496 2379.4945029633536 0.0004265351212103 0.0100895452730284 2365.466469536525 0.000377510336646 0.0134317312243892 3557.9770725539 0.0013733988400954 0.0309701222432521 2254.998427193918 0.0012069155830618 0.0280179052458689 2321.446971029158 +r_0151 adenylosuccinate lyase (AICAR) 0.0023449126491611 0.000282934669138 12.065893765351223 0.003871920472657 0.0010230903499749 26.42333067530268 0.0088619803964999 0.0008362143729859 9.435976334547592 0.0131843147790409 0.0013270928867875 10.06569479740596 0.0186307545079881 0.0024674059468486 13.243725291913142 0.0219395877179189 0.0011162617675378 5.087888532318074 0.0247851287848297 0.0039229086243852 15.827670933008504 0.0292491798032496 0.006141959758171 20.9987418433139 0.0330695281272022 0.0059229817086725 17.910693148961094 +r_0152 adenylosuccinate lyase 0.0026389715881982 0.0028160098551576 106.70860829844074 0.0043036906039915 0.0040519809781574 94.15130758701306 0.0106164374223831 0.0036437940208302 34.32219186021731 0.0169481849350323 0.0060090872521011 35.45563890844881 0.0207412197343953 0.0101472131670063 48.92293364106786 0.0265254943139194 0.0076354412369176 28.78529292067097 0.0311677832808982 0.0189238327460355 60.716004649690056 0.0376592971581449 0.022444449931161 59.59869574014807 0.0408964203509039 0.0212487227527895 51.9574147821959 +r_0153 adenylosuccinate synthase 0.0026389715881982 0.0028160098551576 106.70860829844074 0.0043036906039915 0.0040519809781574 94.15130758701306 0.0106164374223831 0.0036437940208302 34.32219186021731 0.0169481849350323 0.0060090872521011 35.45563890844881 0.0207412197343953 0.0101472131670063 48.92293364106786 0.0265254943139194 0.0076354412369176 28.78529292067097 0.0311677832808982 0.0189238327460355 60.716004649690056 0.0376592971581449 0.022444449931161 59.59869574014805 0.0408964203509039 0.0212487227527895 51.9574147821959 +r_0154 adenylyl-sulfate kinase 0.0019412402170335 0.0018793221244158 96.81038482128996 0.0030703003945363 0.0014835364225149 48.3189340415984 0.0083017687843415 0.0017495495907788 21.07441963547376 0.0139271403436655 0.0025017075816251 17.96282309141102 0.0150532852365792 0.0040550478811824 26.937959504871145 0.0211551691152078 0.0051983963285166 24.572700412872805 0.0244487714992052 0.0070626301289907 28.88746426060856 0.0307595850772754 0.009506262161093 30.90504028975376 0.032504105616499 0.0091574312025812 28.17315237227433 +r_0155 ADP-ribose 2,3-cyclic phosphodiesterase 6.138000000000297e-10 4.885665762819576e-10 79.59703100064097 5.080000000000216e-10 5.524464131550265e-10 108.7492939281502 6.446000000000321e-10 4.795172857838047e-10 74.3898985081882 6.138000000000298e-10 4.8733670025134e-10 79.39666019083033 6.668000000000334e-10 4.739437567232171e-10 71.07734803887121 9.725999999999679e-10 1.8070907878197086e-10 18.57999987476628 6.212000000000303e-10 4.867832696286165e-10 78.36176265753268 7.752000000000367e-10 4.208329598261147e-10 54.28701752142607 8.987999999999934e-10 3.05576889582777e-10 33.99831882318416 +r_0156 alanine glyoxylate aminotransferase 0.0009735903387985 0.0060123002852383 617.5390249514788 0.0003424527490943 0.0053129415057787 1551.437831884524 0.1488170900612411 0.0775226286795158 52.09255781551282 0.0057510240157322 0.0472815930589646 822.1421598940178 0.5980398516392577 0.3004569016132229 50.24028094275913 0.0056607271962838 0.0285348191700775 504.08398392365285 0.5160668113799642 0.2656868438781284 51.48303243289004 0.395419195496977 0.2341194128140238 59.20790277259407 1.431440545428611 0.6948359919415935 48.54103051367329 +r_0157 alanyl-tRNA synthetase 0.0050811704452069 3.754253583517431e-05 0.7388560616105274 0.0086379456421763 5.329104076058128e-05 0.6169411451303681 0.0238523943674857 6.720545748692881e-05 0.2817556026096044 0.0400446713560848 0.0001084146003424 0.2707341493163619 0.0431225678778404 0.0001815656534421 0.4210455508041203 0.0603740915766817 0.0001758470384709 0.291262417170411 0.0699159700854666 0.0003303299580227 0.4724671024644331 0.0879895455061526 0.0005165316097705 0.5870374790541812 0.0931020242987085 0.0004687345181419 0.5034632938141387 +r_0158 alcohol acetyltransferase (2-methylbutanol) 3.1487820865762914e-05 0.0008447314832724 2682.724494888517 1.0333232992849792e-05 0.0003266328302939 3160.993568227872 2.9281539198500488e-05 0.0007821123460562 2671.0083126240866 2.611274292325729e-05 0.000825457489615 3161.129001426418 4.934912123993791e-05 0.0017442311907748 3534.4726450027897 0.0001014208307995 0.0025337801465102 2498.2837613678444 0.0001297263399937 0.0034650053329373 2671.0114022374305 0.0001407287234184 0.0044484520674196 3161.0121653640304 0.0001504662905913 0.0044073109023128 2929.101850647225 +r_0159 alcohol acetyltransferase (ethanol) 9.951163466198126e-05 0.0020971116684716 2107.403496681625 4.430310178966537e-05 0.0018235436654214 4116.063191419414 3.0180289372292603e-05 0.0013779629797605 4565.7712646905375 4.4937816612427066e-05 0.0020394990642436 4538.49167135474 9.951931186986334e-05 0.0042396882953498 4260.166409604905 0.0001586574004132 0.0041957988329924 2644.565473821309 0.0001538176740193 0.0064744164922378 4209.149913046982 0.0002112245721822 0.0088160402547928 4173.775883985146 0.0003970257108604 0.0117917696567521 2970.0267096544644 +r_0160 alcohol acetyltransferase (isoamyl alcohol) 6.548960573314632e-05 0.0015226376466237 2325.0065862788924 9.20985167761292e-05 0.0025584753471249 2777.976710899736 8.149464518896445e-05 0.0022210849548347 2725.4366832135697 7.263915089343163e-05 0.0022182758053787 3053.8294818907216 0.000146841672934 0.0050924491934546 3467.986363614028 0.0002151998117771 0.0057727320849056 2682.49866820646 0.0003601162766041 0.0091955534311018 2553.495642522357 0.0004266729457035 0.0133015267688162 3117.4994577830344 0.0003218034395101 0.0111603148778031 3468.0533231069 +r_0161 alcohol acetyltransferase (isobutyl alcohol) 6.56943750293821e-05 0.0015104864663563 2299.2630125194432 4.268071489797325e-05 0.0016538135816047 3874.849766594021 5.9428276439182615e-05 0.0017169139601861 2889.0522543477127 0.0001282553905544 0.003308582236478 2579.6827892965 0.0002109676042536 0.0060385009413804 2862.2882469289675 0.0001329767124521 0.0043735320225032 3288.945817545625 0.0004035305517002 0.0096004933378469 2379.1242812709734 0.000351419722403 0.0118557627256019 3373.675969160713 0.0003325136159888 0.0113129186952276 3402.242239490134 +r_0162 alcohol acetyltransferase (phenylethanol alcohol) 1.779951269305774e-05 0.0004538551748345 2549.817979070566 8.213347859834758e-06 0.0002596221673242 3160.9785894229244 1.7869397047198672e-05 0.0005156500296449 2885.659926201935 2.48434261889528e-05 0.0007168450579602 2885.4516784766565 2.6326196656315315e-05 0.0010231113752172 3886.286304755092 7.194890475863155e-05 0.0017974781558502 2498.270351550553 4.645175490053061e-05 0.0016928001920424 3644.2114957063295 0.0001368689856359 0.0036638344083925 2676.891621113661 8.844872593456675e-05 0.0028456035164653 3217.23516805716 +r_0163 alcohol dehydrogenase (ethanol to acetaldehyde) 1.4000000000000003e-11 1.1750217594696317e-10 839.3012567640224 0.0091270039251583 0.1628867263854156 1784.668087371174 7.000000000000001e-12 8.338099590491929e-11 1191.1570843559898 1.5579999999999924e-10 6.428133491149385e-10 412.5887991751872 0.0345664185138893 0.607645548325364 1757.907166694758 4.799999999999999e-12 6.912246800510025e-11 1440.0514167729225 5.599999999999999e-12 7.463078420323867e-11 1332.6925750578337 3.559999999999991e-11 1.8530922238675435e-10 520.5315235583 0.008650116042243 0.0997666752722271 1153.3564958552492 +r_0164 alcohol dehydrogenase (glycerol, NADP) 5.240076056798884e-11 8.870739172646713e-10 1692.8645837376969 -1.9820190129595142e-10 1.049149195428114e-09 -529.3335677247331 -7.451195445453276e-11 1.117337479563223e-09 -1499.5412316623942 -8.211444385817626e-11 9.424828321995035e-10 -1147.767418150344 -2.6864209906538704e-10 9.047052506822815e-10 -336.769722180468 5.036666666848177e-11 8.219512608436052e-10 1631.93499830705 -1.80933333333339e-10 9.644712154281903e-10 -533.0533615115108 -2.466666666666727e-11 8.691940006426627e-10 -3523.759462064764 -1.6266006650760236e-10 9.245612494131523e-10 -568.4008799848489 +r_0165 mitochondrial alcohol dehydrogenase 0.0003103370079013 0.0043017459959308 1386.1530808140517 0.0090232603757737 0.1624683915421206 1800.5508516447828 0.0018367647043478 0.0202968965978302 1105.035204007614 0.0008269276645308 0.0064192452981216 776.2765201190203 0.0356328732009909 0.609621143559516 1710.8391459787274 0.0040113501205198 0.0451296307090293 1125.0484089676072 0.0015494975127681 0.0225736466789679 1456.8365868907113 0.010657302798719 0.1679831163036246 1576.2254247276817 5.656130774635528 0.2334561019627707 4.127487699005939 +r_0166 aldehyde dehydrogenase (2-methylbutanol, NAD) 0.000131559626595 0.0016614943153269 1262.921124305771 2.070267497921177e-05 0.0004895748059939 2364.7900886505045 4.450086383380358e-05 0.0009983483306556 2243.4358451649905 6.176309099040122e-05 0.0013233478847781 2142.6192626657926 0.0001386181605317 0.0031018344692177 2237.6826076177063 0.0002569325928383 0.0038027859954054 1480.07146675952 0.0002079246856946 0.0044882027329909 2158.5713682802543 0.0003792886481604 0.0077668523051543 2047.741830087104 0.0003840010899415 0.0075511722307221 1966.445520212471 +r_0167 aldehyde dehydrogenase (2-methylbutanol, NAD) 1.7105954506717697e-05 0.0006981997678232 4081.618289988178 1.417158934886823e-05 0.0004100214547386 2893.263731011131 4.056671111780028e-05 0.00101345887099 2498.2524909329463 5.690693913398834e-05 0.0013402386195045 2355.1409369407943 4.712171930996499e-05 0.0018077239174542 3836.285992799038 1.3907428218745937e-05 0.0007204791116281 5180.534461842506 6.650158293808138e-05 0.0027149520188143 4082.5374357512105 0.0002047514548417 0.0059077112424437 2885.308554710331 0.0002623238453939 0.0065535040106596 2498.249444619547 +r_0168 aldehyde dehydrogenase (2-methylbutanol, NADP) 1.060344239819984e-05 0.0005301191941836 4999.500862792115 4.82515832609416e-06 0.0002412316980119 4999.45663352484 9.426230787412744e-06 0.0004712651412252 4999.507776263871 6.138367903980747e-06 0.0004340465651408 7071.041878402492 2.777042735904185e-05 0.0013883882536563 4999.520661695105 2.863410116829509e-05 0.0014315633679808 4999.505168913526 6.279381310981436e-05 0.0025630338221783 4081.666163028005 6.348217039825752e-05 0.003173792178425 4999.501684511035 6.089472909525107e-05 0.0030444401256213 4999.513374727778 +r_0169 aldehyde dehydrogenase (2-phenylethanol, NAD) 0.0001095168594956 0.0012525115363874 1143.6700633628573 1.5787693493232214e-05 0.00037275954016 2361.076621609232 4.511252787123439e-05 0.0008534160137012 1891.749485059081 4.8504446836580136e-05 0.0010354947000885 2134.844880464892 7.657977610313076e-05 0.0018887855665075 2466.428687338978 0.000170553027451 0.002657717089802 1558.2937046162083 0.0001070925601432 0.0027301176780304 2549.306575899627 0.0003191541703704 0.0058406129234572 1830.0287026418869 0.0001765195118127 0.0042155891485501 2388.171769374162 +r_0170 aldehyde dehydrogenase (2-phenylethanol, NAD) 2.026820198746517e-05 0.0005427500115088 2677.839957606876 1.89355404315836e-06 0.0001338969502703 7071.197717020623 1.372180151670588e-05 0.0004849945798535 3534.481819046317 9.584328672517323e-06 0.0004791732627242 4999.54956780945 6.008283080013696e-05 0.0017336031956606 2885.3553878434386 2.0837003386372587e-05 0.0010417131932245 4999.342630552214 6.0417557335762815e-05 0.0021354631604139 3534.5076076915225 9.119857637319492e-05 0.0032234021437558 3534.4873483171027 -3.423630176494415e-11 5.498808923848804e-10 -1606.134027443129 +r_0171 aldehyde dehydrogenase (2-phenylethanol, NADP) 1.9024835436754867e-12 1.0596209828096347e-10 5569.672265140907 1.8511069685523009e-06 0.0001308930290164 7071.067811865148 3.2662604473513024e-06 0.0002309594911443 7071.0678118658025 4.5743835390547584e-06 0.0003234577620213 7071.067811865154 9.590872780321329e-06 0.0006781771180462 7071.06781186555 7.0064893709957134e-06 0.0004954336146542 7071.067811865234 1.4466171524916922e-05 0.0010229127983076 7071.067811865482 2.178880852072293e-05 0.0015407013788491 7071.067595934799 2.100986804209363e-05 0.0014856220164399 7071.067811865672 +r_0172 aldehyde dehydrogenase (3-aminopropanal, NAD) 6.851207203319095e-05 0.0006796917189338 992.0758470193852 0.0001082615334275 0.0011640808051362 1075.2487686825543 9.915198577949708e-05 0.0009605998832043 968.8155770683616 0.0001429420954476 0.0013500434072052 944.4687395811692 0.0003189565105946 0.0030179632197609 946.1989705536832 0.0002784900017764 0.0026016288690635 934.1911208545092 0.0003697077275596 0.0039439112865126 1066.764633930037 0.0006302500066852 0.0065214491956122 1034.7400438614563 0.000648357227037 0.0064686996364464 997.7061050138168 +r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.000200242294739 0.0026629245423585 1329.8511914423905 0.0006603955642768 0.005762094142413 872.5216300812491 0.0018283740141172 0.0147249861090537 805.3596252932648 0.0027797954535866 0.0215090232932445 773.7628056586774 0.0034428659469084 0.0278113895243314 807.7976300327555 0.0051036000814249 0.0389797620797109 763.7699164866366 0.004372219994026 0.0365049131275075 834.9285529407498 0.0059944359272363 0.0478372357478919 798.0273094677407 0.0076407214611374 0.0577580449580891 755.9239693772394 +r_0174 aldehyde dehydrogenase (acetylaldehyde, NAD) 9.85252942585854e-05 0.0023592544397232 2394.567260597285 0.0002202473649196 0.005006263944509 2273.018769752515 7.317459637738303e-05 0.0022458035419664 3069.102739404548 5.086326401714325e-05 0.0019447532633664 3823.492850775252 0.0001479613427216 0.005400968605454 3650.256550871887 7.641554910828638e-05 0.0035264531024699 4614.837089598961 0.0003022222638956 0.0095646713100058 3164.780511771909 0.0005822604323137 0.0164690675202799 2828.4710082114307 0.0004546487258283 0.0150886392754828 3318.746631916863 +r_0175 aldehyde dehydrogenase (acetylaldehyde, NADP) 4.8017852841795785e-05 0.0011790886630582 2455.521422298888 6.166464847260394e-05 0.0018023908754265 2922.89167305846 0.0001158568934974 0.0031425148298311 2712.4107465389907 0.0002240626808417 0.005219611060579 2329.531647559498 0.0002754008666102 0.0065549900926644 2380.1632047665885 0.000299289072259 0.0077831687820875 2600.5522765467226 0.000393068723155 0.0094885484564117 2413.966794470321 0.0003367715764849 0.0089779573825895 2665.889288014594 0.0005329682015683 0.0133822681175731 2510.8942856617587 +r_0176 aldehyde dehydrogenase (indole-3-acetaldehyde, NAD) -6.440000000000002e-11 3.4853541482478517e-10 -541.2040602869333 5.999999999999866e-13 6.022226950513421e-10 100370.44917522592 1.2879999999999986e-10 3.9829924486207907e-10 309.2385441475773 1.1799999999999947e-11 5.303932723976391e-10 4494.858240657978 -3.519999999999998e-11 3.8831832074170325e-10 -1103.1770475616577 8.600000000000011e-12 1.8690378970294988e-10 2173.2998802668567 4.9199999999999866e-11 3.091900381576634e-10 628.4350369058216 3.759999999999989e-11 2.6419727485348107e-10 702.6523267379838 4.999999999999999e-12 1.6787089124450028e-10 3357.417824890007 +r_0177 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 2.2680000000000068e-10 4.3931806253784237e-10 193.7028494434925 5.270000000000249e-10 7.857445379357136e-10 149.0976352819121 5.828000000000274e-10 5.462635268514348e-10 93.73087282968584 7.632398202757175e-10 5.004407936137255e-10 65.56796177549325 1.0660000000000058e-10 4.846477243146212e-10 454.6413924152144 2.6199999999999955e-11 3.1864379293083323e-10 1216.1976829421135 2.592000000000032e-10 6.293604522972096e-10 242.808816472686 2.7760000000000445e-10 5.167123361481543e-10 186.13556777670968 9.380000000000088e-11 3.6363168948969615e-10 387.667046364278 +r_0178 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) -1.5940000000000066e-10 5.261625313549771e-10 -330.08941741215506 6.180000000000044e-11 5.481248472470939e-10 886.9334097849352 -2.578e-10 7.314685018740117e-10 -283.7348727207184 -1.183958477032334e-10 6.765222468759732e-10 -571.4070721227645 -1.6400000000000032e-11 3.700789533144512e-10 -2256.578983624698 -5.48062726227487e-11 3.713310824482987e-10 -677.5339111351436 -1.2740000000000038e-10 5.359353368990391e-10 -420.6713790416306 -1.0500000000000008e-10 4.72884472090996e-10 -450.3661638961864 -6.399999999999998e-12 2.1626001405423188e-10 -3379.062719597374 +r_0179 aldehyde dehydrogenase (isoamyl alcohol, NAD) 6.397796854233051e-05 0.0013215354972329 2065.610283262646 2.1869691805827305e-05 0.0004949479349717 2263.1683124126803 5.722048243703325e-05 0.0012234132107136 2138.0686750761693 9.591407089276075e-05 0.0016992804708883 1771.669636239557 0.0001553095032325 0.0034799993667976 2240.686689716958 7.234555111415222e-05 0.0022945612581594 3171.668779658468 0.0003354580647954 0.0061442223341387 1831.59177821074 0.0002776226755612 0.006961008185334 2507.3629779205044 0.0003050896031058 0.0072085186028697 2362.754590613892 +r_0180 aldehyde dehydrogenase (isoamyl alcohol, NAD) 5.247841301084752e-05 0.0012131569100951 2311.725603905658 1.796080373536082e-05 0.0004797354206987 2671.013100345149 2.7376846541264165e-05 0.0008653885547307 3161.0235073142703 4.604295817903487e-05 0.0012204309432414 2650.6353881432515 0.0001454947566655 0.0034266002401439 2355.136582702792 0.0001370794271951 0.003332456012611 2431.04022302916 0.0001939714839014 0.0048459707723054 2498.2903026958857 0.0002209870716657 0.0063761856843064 2885.3206824477115 0.0002125744326901 0.0061334265023139 2885.307713019049 +r_0181 aldehyde dehydrogenase (isoamyl alcohol, NADP) 1.1403825692432256e-05 0.0005701340971382 4999.498523698287 4.973685347113453e-06 0.0002486579957444 4999.471787830819 5.073208278450181e-06 0.000358721885362 7070.9079082333465 0.0 0.0 2.9634365781747323e-05 0.0014816402563738 4999.736681681872 4.621680149565097e-05 0.0018864155482814 4081.666163027304 4.497997045848273e-05 0.0022487735768356 4999.499897207052 0.0001023955003257 0.0041794425011971 4081.666174686926 6.558149188842251e-05 0.0032787466049638 4999.499874967957 +r_0182 aldehyde dehydrogenase (isobutyl alcohol, NAD) 0.0001210759559405 0.0017690212472071 1461.0838572080545 2.367924554987317e-05 0.0005957522116858 2515.925646495421 8.137284685578783e-05 0.0016709671706552 2053.4702117730244 6.138510756116283e-05 0.0015125783188712 2464.080261428435 0.0002040608989466 0.0045902561354375 2249.4540400104424 0.0003871278295573 0.0056540470742307 1460.5116559808534 0.0004249334461681 0.0079075571294084 1860.8930882507584 0.0006215823679385 0.0122277653258806 1967.199514753574 0.000501766662491 0.0107648143784987 2145.382541967903 +r_0183 aldehyde dehydrogenase (isobutyl alcohol, NAD) 3.793154013768106e-05 0.0012242994000625 3227.655390787289 2.3187514060440483e-05 0.0006193436251041 2671.022100470984 5.493920905301429e-05 0.0014068497851739 2560.739059450904 4.964069493098872e-05 0.0014335391890013 2887.8306216186406 4.514391578995459e-05 0.0021861985810782 4842.731390981235 0.0001444784471434 0.0039354931525847 2723.930960219901 0.000109639758281 0.0040957631976393 3735.655077913124 0.0001295473135519 0.0054230937172707 4186.187709016362 0.000192645577228 0.0068090063605889 3534.4732324314364 +r_0184 aldehyde dehydrogenase (isobutyl alcohol, NADP) 2.279063217883175e-05 0.0009244289325084 4056.179421679352 6.364044344790317e-06 0.0003181703890606 4999.4998749672295 1.3432987801826312e-05 0.0006715822083568 4999.499874968321 1.6192251700562255e-05 0.0008095316035246 4999.499874971461 5.9427468460580825e-05 0.002425630871699 4081.6661630270096 4.079228812565162e-05 0.0020394103938383 4999.499874967539 5.955092964009243e-05 0.0029772486528986 4999.49987496796 0.0001353026825936 0.0055226262042411 4081.682711959653 0.0001302392488156 0.0053159313498871 4081.6661630269728 +r_0185 aldehyde dehydrogenase (phenylacetaldehyde, NAD) 5.199999999999999e-12 7.465972686102689e-11 1435.7639780966715 7.652463039852828e-10 4.290980121620777e-10 56.073189759611054 6.199999999999999e-12 7.850345571063667e-11 1266.1847695263982 7.560000000000048e-11 2.643834709733992e-10 349.7135859436475 6.599999999999999e-12 8.097994535877668e-11 1226.968869072374 1.2e-12 3.462368784447926e-11 2885.307320373272 8.400000000000003e-12 9.127489370710819e-11 1086.6058774655737 9.800000000000008e-12 9.851853216647464e-11 1005.2911445558628 9.800000000000008e-12 9.851853216647527e-11 1005.2911445558696 +r_0186 aldehyde dehydrogenase (tryptophol, NAD) 1.8309047537788004e-05 0.0003597425872803 1964.8350715016795 8.44681825571076e-06 0.0002437202570391 2885.349840152643 1.655295485563075e-05 0.0004135391663973 2498.280035220897 2.3640854099116e-05 0.0005906115902239 2498.2667197546425 1.8312621432081744e-05 0.0007474639223069 4081.687185415634 3.773412674987239e-05 0.0010078479548345 2670.918984067871 3.6733869364049854e-05 0.0012983504717861 3534.4778382012564 4.185155796806913e-05 0.0017082389965406 4081.661662019712 4.017194523378885e-05 0.0016396858689617 4081.6690837829615 +r_0187 aldehyde dehydrogenase (tryptophol, NAD) 5.48925591425648e-06 0.0001947375065712 3547.6120919310374 1.193461694841847e-06 8.44179239294684e-05 7073.36685327426 1.6582807578981435e-05 0.0004142866666378 2498.290260347512 1.7536173698405705e-05 0.0005061652069575 2886.4062118840634 3.5849314633662564e-05 0.0010346962973847 2886.2373185041074 3.234243073390174e-05 0.0009331796061768 2885.3106739398013 4.571020333752961e-05 0.0014449686587275 3161.151238067708 6.972007154494036e-05 0.0022038641154828 3161.018149647633 3.9990192557578445e-05 0.0016323179147905 4081.795586356193 +r_0188 alkaline phosphatase (dihydroneopterin) 3.188174335825956e-09 7.892642609035243e-08 2475.5994427106843 -3.518272014862038e-09 1.5413261851034938e-07 -4380.918185383496 -3.564844707824066e-09 4.739339231047334e-07 -13294.658307683094 6.062876344745391e-08 6.958229758347933e-07 1147.6779935283575 9.476800011853545e-08 1.0307834503419898e-06 1087.691466584385 1.0816322740571337e-07 1.2055107966246647e-06 1114.5292402406512 8.172357643900085e-08 1.109440627948078e-06 1357.552711580328 1.813989101428157e-07 1.7880304128544723e-06 985.689721865888 2.422769976713804e-07 2.195840380851676e-06 906.3346508157034 +r_0189 allantoate amidinohydrolase 1.0814500227433907e-09 5.078649484130021e-10 46.96148113480686 -3.1926946733673945e-10 6.522446541505016e-10 -204.29283751789745 -3.8488277872467655e-10 8.006173323714551e-10 -208.0158886361013 -5.635206566592266e-10 7.332465826255599e-10 -130.11884727927026 -5.47711897727823e-10 6.81953576488075e-10 -124.5095422095361 1.0461306812646735e-09 8.30898604695496e-10 79.42589005142435 -8.213892584206426e-10 7.96133088183387e-10 -96.92518863884128 -5.34867311504088e-10 1.0040675728010715e-09 -187.72274005258544 -7.134539783443518e-10 9.84913942238888e-10 -138.04870000507802 +r_0190 allantoinase, reaction 2.598750189528791e-11 5.155614295942667e-10 1983.8822202750816 -1.3278195640909874e-10 3.852401851883904e-10 -290.12992096717755 -3.7041856318000177e-10 6.109429714930924e-10 -164.93314110616254 -3.0931762492897795e-10 5.131800347903975e-10 -165.9071431536526 -5.430916588864523e-10 5.42184706033957e-10 -99.8330018814218 4.4628878187440565e-10 7.753767343181814e-10 173.73879107191803 -8.062832296192415e-10 6.648132015682945e-10 -82.45405301090605 -6.93254196704578e-10 7.937470785429286e-10 -114.4958201935234 -6.187190154972993e-10 7.160351600726377e-10 -115.72864937682904 +r_0191 allophanate hydrolase 2.2084051764287674e-05 0.0005200658492139 2354.938553689483 4.358923884859727e-05 0.0009771525644626 2241.728899778792 2.260331663815958e-05 0.0006522041041817 2885.4354191571724 1.666780635642271e-05 0.0006803470166458 4081.802980532741 7.813600462810236e-05 0.0020870214686943 2671.0112433158097 7.271419336148146e-05 0.0018165866170908 2498.255888035717 6.700754795913863e-05 0.0023683842515471 3534.50368455714 0.0002543097905169 0.0056814606987191 2234.0707713888664 0.0001712404585444 0.0045738471238515 2671.008453685352 +r_0192 alpha 1,2-mannosyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0193 alpha,alpha-trehalase 2.766772607232632e-05 0.0008745849454739 3161.0293639156384 4.031423003732902e-05 0.0014249071370418 3534.501677751252 4.83615626846423e-05 0.0014064844729676 2908.269284305562 9.413906439620345e-05 0.0023907858294607 2539.6320271451423 0.0001484585058831 0.0042855639443307 2886.708254832938 0.0001026008320326 0.0032432465706684 3161.0334014007176 0.0002230637824844 0.0064397359624566 2886.9482489410952 0.0004583729397855 0.0114513146286932 2498.2527620525966 0.0003852906984875 0.0102911582771466 2671.011347417366 +r_0194 alpha,alpha-trehalase 2.7684900658205464e-05 0.0008750674804925 3160.811343685416 8.03225890466223e-05 0.0020067644408778 2498.381171096292 5.1092807616114445e-05 0.0014741913455775 2885.320682812909 3.774540219730208e-05 0.0015403583971631 4080.916634856361 7.5344910282442e-05 0.0030753327424196 4081.6728441129335 0.000100187745806 0.003170288930848 3164.34800018786 0.0002224971391913 0.0064249382540155 2887.649826584791 0.0001145930965253 0.0057290689412858 4999.488725760622 0.0001651239886338 0.0067398127615135 4081.667852911884 +r_0195 alpha,alpha-trehalose-phosphate synthase (UDP-forming) 0.0041534285144864 0.0012366509657535 29.77422053708967 0.0066255725932835 0.0024597878838437 37.125664977806174 0.0133980384893657 0.0020362559115186 15.198164366633671 0.017714913178313 0.002842720903976 16.047049598053707 0.0313724157964781 0.0052731264461366 16.808161922706045 0.0327075269804946 0.0045331090469501 13.859528571675703 0.0357284868531553 0.009090939908975 25.444514194902656 0.0392078864159326 0.0128001720191976 32.64693200599586 0.0475341270901428 0.0122965353135069 25.86885689556896 +r_0198 alpha-glucosidase 8.635349260861517e-10 1.472155415443017e-09 170.48012430896696 8.616000000000064e-10 3.459326146445017e-10 40.150024912314194 8.222000000000202e-10 3.8238253527148734e-10 46.507240971962766 8.710000000000031e-10 3.3523346535698165e-10 38.48834275051441 8.246000000000195e-10 3.8401084993341187e-10 46.56934876708741 8.120000000000239e-10 3.9075124735241624e-10 48.12207479709419 8.248000000000192e-10 3.8070191329877815e-10 46.156876006155336 8.164000000000221e-10 3.871963638837847e-10 47.42728612001153 8.332000000000163e-10 3.7283449560389216e-10 44.74729904031263 +r_0199 amidase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0200 Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing) 4.699999999999986e-11 2.1260301034557987e-10 452.34683052251165 1.0400000000000007e-11 1.0721072160827055e-10 1030.8723231564468 5.799999999999999e-12 7.594414725770827e-11 1309.3818492708324 4.4e-12 6.619302307087238e-11 1504.3868879743725 4e-12 7.200720108018439e-11 1800.18002700461 5.38e-11 2.2741130838336047e-10 422.6975992255772 2.2000000000000003e-12 4.6857220572966754e-11 2129.87366240758 3.8e-12 6.15330582975774e-11 1619.2910078309844 1.2e-12 4.8979993956325663e-11 4081.666163027139 +r_0201 Aminobutyraldehyde dehydrogenase 0.0001458101253784 0.0039410676013795 2702.876491704277 0.0001209437065622 0.0049365170678335 4081.665105322495 0.0001021855111817 0.0041709016967708 4081.695779115224 0.000201278422821 0.0071139348881619 3534.375313784112 0.00130578510829 0.0255778176848113 1958.8075803916408 0.0002462427868652 0.010050844760993 4081.6808845220216 0.0006023576891763 0.0212904371332265 3534.517366639416 0.0008395153351485 0.0297052479126571 3538.3806190269524 0.0007968358203101 0.0286280799143992 3592.7200038844 +r_0202 anthranilate phosphoribosyltransferase 0.0007737518153022 0.0008148460998492 105.31104208537975 0.0012740322982829 0.0011740986210346 92.15611116115667 0.0032656281549016 0.0010881926658049 33.32261403281786 0.0053687698439837 0.0016457218085825 30.65361072288676 0.0061360165776296 0.0031701864750798 51.66522017944892 0.0082570269353028 0.0029871037225422 36.17650452090633 0.0095591523757171 0.0044449359943102 46.49926917789934 0.0121484645565081 0.0073750348900048 60.70754749046805 0.0129384841067491 0.0075400232207679 58.27593989032178 +r_0203 anthranilate synthase 0.0007252675670267 0.0004087910185758 56.36416643469623 0.0012117083338259 0.0004538381933754 37.45440884626554 0.0032109317258547 0.0006727177982146 20.950859614915977 0.005283421668826 0.0009984920605912 18.89858737724165 0.0059694768283756 0.001697751604338 28.4405426664496 0.0080988000650059 0.0016786651687551 20.727331892146367 0.0093459848326087 0.0025162293332819 26.923105251601186 0.0117463606585514 0.0043472978409189 37.009742568683535 0.012515512800913 0.0041920427758162 33.494774385196976 +r_0204 Ap4A hydrolase 0.0001033505278586 0.0027605009716391 2671.008101104486 2.687699101510706e-05 0.0019004446045694 7070.897942039909 0.0001135407156069 0.0035890359336539 3161.012254034002 0.0002348184465057 0.0062720196770555 2671.0080789598223 0.0004018429799588 0.0115944033095246 2885.306920307812 0.0002736041070391 0.0086486593332071 3161.012247513017 0.0007046860346582 0.0188222207190201 2671.008050861712 0.000458373648655 0.0187092821500606 4081.666170155499 0.0008806655109422 0.0254099064841104 2885.307323654003 +r_0205 arabinose reductase 7.200000000000001e-12 1.3839071644470215e-10 1922.0932839541963 -2.400000000000001e-12 7.480213280257701e-11 -3116.755533440708 -1.8000000000000002e-12 4.2392445363355096e-11 -2355.135853519728 -2.2000000000000003e-12 5.094780795899906e-11 -2315.809452681775 -4.2e-12 6.769990144255447e-11 -1611.902415298916 -9.999999999999998e-13 1.0677677770026508e-10 -10677.67777002651 -6.8e-12 8.218948243056736e-11 -1208.6688592730495 -1.2e-12 7.745811740540989e-11 -6454.843117117491 -1e-12 4.68981864039265e-11 -4689.81864039265 +r_0206 arginase 2.208282633923123e-05 0.0005200658445895 2355.0692135166246 4.359005952368612e-05 0.0009771526265983 2241.6868370352577 2.260445840162649e-05 0.0006522041229672 2885.2897573531754 1.6669196358186722e-05 0.0006803469993334 4081.462505535434 7.81373166757073e-05 0.0020870215051547 2670.966439526615 7.271291532131944e-05 0.0018165866084106 2498.2997867477843 6.700936797202042e-05 0.002368384278119 3534.407725063157 0.0002543110120296 0.00568146073783 2234.06005602628 0.0001712422417551 0.0045738470677756 2670.9806067095924 +r_0207 argininosuccinate lyase 0.002861161069285 0.0005202972763565 18.18482999583735 0.0048700000146793 0.0009773263829395 20.06830349063039 0.0133500158986377 0.000653011937969 4.8914693654836015 0.0223914390832313 0.000682725606117 3.049047466664655 0.0241726675444535 0.0020886653479376 8.64060759573447 0.0338064504624761 0.0018183514787152 5.37871161816743 0.0391322266095457 0.0023743961354684 6.067623391737382 0.0494180536425618 0.0056859661097121 11.505847945446144 0.0521915577735127 0.0045791989390874 8.773830738984788 +r_0208 argininosuccinate synthase 0.002861161069285 0.0005202972763565 18.18482999583735 0.0048700000146793 0.0009773263829395 20.06830349063039 0.0133500158986377 0.000653011937969 4.8914693654836015 0.0223914390832313 0.000682725606117 3.049047466664655 0.0241726675444535 0.0020886653479376 8.64060759573447 0.0338064504624761 0.0018183514787152 5.378711618167431 0.0391322266095457 0.0023743961354684 6.067623391737382 0.0494180536425618 0.0056859661097121 11.505847945446144 0.0521915577735127 0.0045791989390874 8.773830738984788 +r_0209 arginyl-tRNA synthetase 0.0028390800626344 2.0976715136749457e-05 0.7388560616104769 0.004826411455156 2.977611810014252e-05 0.6169411451303534 0.0133274130488367 3.755073294801978e-05 0.2817556026095948 0.0223747715782747 6.057614749392403e-05 0.2707341493163739 0.024094531768182 0.000101448953997 0.4210455508040757 0.0337337394097261 9.825370480673366e-05 0.2912624171704045 0.0390652191005762 0.0001845703087558 0.4724671024643627 0.0491637442712402 0.0002886096049785 0.5870374790541955 0.0520203177255484 0.0002619032050736 0.5034632938142043 +r_0210 arginyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0211 asparagine synthase (glutamine-hydrolysing) 0.0028088274294993 0.0005539032873453 19.72008965477984 0.0047863932278112 0.0012342772918853 25.787210392861287 0.013166860795607 0.0011828931629174 8.983866247846187 0.0220742471498445 0.0012589933969531 5.703448857878919 0.0239081894369556 0.004449783374608 18.61196301100867 0.0333658386361259 0.0035530010808103 10.64861914474232 0.0385720946994651 0.0037782892573539 9.795395574942138 0.0488488549990206 0.0107049912021896 21.9145181650712 0.0515932802811099 0.009527704896833 18.466949271146635 +r_0212 Asparaginyl-tRNA synthetase 0.002797754962275 2.067138212777855e-05 0.7388560616105264 0.0047561591457841 2.934270269822458e-05 0.6169411451303924 0.0131334218018061 3.700415174093632e-05 0.2817556026095767 0.0220490887301028 5.969441280546017e-05 0.2707341493163908 0.0237438164232596 9.997228264121684e-05 0.4210455508040538 0.0332427176224363 9.68235428802442e-05 0.2912624171704168 0.0384965933259338 0.0001818837390345 0.4724671024644113 0.0484481263171116 0.0002844086593809 0.5870374790541752 0.0512631200406382 0.0002580909926684 0.5034632938141026 +r_0213 asparaginyl-tRNA synthetase, miotchondrial 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0214 aspartate carbamoyltransferase 0.0024701106957942 0.0004401585674912 17.819386323079108 0.0040302650511452 0.0007797818850133 19.348153908431325 0.0092811312718676 0.0008659586475509 9.33031353813272 0.0137847495071843 0.0012153660941694 8.816744138412211 0.0195994106820898 0.0032437220889671 16.55010011056755 0.0230521584841813 0.0017647724722386 7.655562811828072 0.0258180671812165 0.0031838440253061 12.331844994277908 0.0307712975186701 0.0074638682578432 24.255942581929187 0.0347037674799232 0.0067703518754673 19.50898235871385 +r_0215 aspartate kinase 0.0053870960704487 0.0018843036506109 34.97809628730028 0.0090785145339951 0.0028154390275674 31.012111254818315 0.0247814731772187 0.0043479302684385 17.545083931634682 0.0417544932174312 0.0065918868249742 15.787251423811773 0.0452739826779653 0.0118604805618436 26.1971221887137 0.0626066082037092 0.0087029872614842 13.901068131923829 0.073593581294156 0.0198944569359328 27.03286969608671 0.0928222026026762 0.0280974450174684 30.27017699390203 0.0976629712441072 0.0264096710825582 27.04164203293353 +r_0216 aspartate transaminase -0.0220195676993326 0.003571277195509 -16.218652628758452 -0.0368876819052366 0.0054527395419974 -14.782006513733586 -0.0965158380061365 0.0059945070823205 -6.2109050764698175 -0.1577824226861368 0.0093770381779503 -5.943018251534453 -0.1820473659706025 0.016673346836829 -9.158795980339264 -0.2429745138091161 0.0122955366734024 -5.060422379551275 -0.2815151641627402 0.0286200247370087 -10.166423830889574 -0.3493681876463336 0.0384553893860253 -11.00712392994232 -0.3744422324545149 0.0359460835764304 -9.599900988945452 +r_0217 aspartate transaminase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0218 aspartate transaminase 7.392085921526076e-06 0.000926882430664 12538.848174977064 6.475791856084143e-06 0.0017400434930222 26869.97253297257 4.301694958897684e-06 0.001495253119552 34759.62693401287 -9.228390696620264e-06 0.0023974489839807 -25979.05813479195 7.865111692807987e-05 0.004087554278768 5197.070859789346 7.016389128225416e-05 0.0033611465984387 4790.4221630432985 0.000194982529027 0.0066589009901241 3415.126997967858 0.0001805463636086 0.0089051257847062 4932.320766099301 0.0003015735507947 0.0076999572044007 2553.260119830772 +r_0219 aspartate-semialdehyde dehydrogenase 0.0053870960704487 0.0018843036506109 34.97809628730028 0.0090785145339951 0.0028154390275674 31.012111254818315 0.0247814731772187 0.0043479302684385 17.545083931634682 0.0417544932174312 0.0065918868249742 15.787251423811773 0.0452739826779653 0.0118604805618436 26.1971221887137 0.0626066082037092 0.0087029872614842 13.901068131923829 0.073593581294156 0.0198944569359328 27.03286969608671 0.0928222026026762 0.0280974450174684 30.27017699390203 0.0976629712441072 0.0264096710825582 27.04164203293353 +r_0220 Aspartyl-tRNA synthetase 0.0035121691232482 2.594987446113596e-05 0.7388560616106096 0.0059706570169017 3.6835439771885305e-05 0.6169411451304471 0.0164870759437027 4.645326017788493e-05 0.2817556026096173 0.0276793821038095 7.493753967478123e-05 0.2707341493163879 0.0298068630149234 0.0001255004705586 0.4210455508040909 0.0417313338661628 0.000121547691736 0.2912624171703838 0.0483268006858093 0.000228328234914 0.4724671024644375 0.0608194840594075 0.000357033165996 0.5870374790541312 0.0643532939073801 0.0003239952131839 0.5034632938141185 +r_0221 Aspartyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0222 ATP adenylyltransferase 0.0001033505278586 0.0027605009716391 2671.008101104486 2.687699101510706e-05 0.0019004446045694 7070.897942039909 0.0001135407156069 0.0035890359336539 3161.012254034002 0.0002348184465057 0.0062720196770555 2671.0080789598223 0.0004018429799588 0.0115944033095246 2885.306920307812 0.0002736041070391 0.0086486593332071 3161.012247513017 0.0007046860346582 0.0188222207190201 2671.008050861712 0.000458373648655 0.0187092821500606 4081.666170155499 0.0008806655109422 0.0254099064841104 2885.307323654003 +r_0223 ATP adenylyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0224 ATP adenylyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0225 ATP phosphoribosyltransferase 0.0012210915771837 9.021931166536272e-06 0.7388414870032893 0.0020758457702125 1.2806641836838752e-05 0.6169360951862737 0.0057321391952357 1.615044921403674e-05 0.2817525650364555 0.0096234216258816 2.605370946226468e-05 0.2707322870713116 0.0103630930236677 4.3633162871352114e-05 0.421043821296408 0.0145089306513367 4.2258876478896095e-05 0.2912611376704218 0.0168020079876638 7.938376625226801e-05 0.4724659475852663 0.0211453987638836 0.0001241312340728 0.5870366194506329 0.0223740152239199 0.0001126447669531 0.5034624577920431 +r_0226 ATP synthase 2.500026305398612 0.0843889977598596 3.3755243925885194 4.548626780863886 0.1897625854430656 4.171865369157094 7.161085057096416 0.2220652743537105 3.1010003733114533 12.075793751541342 0.3748217554132926 3.1039098805861167 16.60771825588897 0.6799830227582562 4.0943795666640685 17.5900315947039 0.535769028547432 3.045867346302802 23.577732999189017 0.7954963261515509 3.3739305054430506 28.68608407957638 1.1172299423886634 3.894675687658941 28.14281969998371 0.9615538629476788 3.4166933988787034 +r_0227 ATPase, plasma membrane 0.0927756486901816 0.0109876868070428 11.843287502882935 0.2350269981817205 0.0367139194930757 15.621149815600708 0.4441225812517514 0.0532156491160186 11.982198465574823 1.474107091088468 0.0893935381639648 6.064249924878756 0.8582307270919968 0.167654099396232 19.5348516551378 1.0300540166895258 0.1888286868023268 18.331920825783524 1.2831195484298643 0.157962506186619 12.310817521244658 1.5674136530964426 0.1587625141665665 10.12894801910966 1.8122401905569543 0.4174254074196651 23.03366902437905 +r_0228 beta-1,4 mannosyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0229 biotin synthase -9.987999999999587e-10 4.897999395632864e-11 -4.903884056500868 -9.851999999999635e-10 1.7025497746458775e-10 -17.281260400385108 -9.979999999999591e-10 6.322024485773655e-11 -6.334693873520955 -9.86799999999963e-10 1.6072002421987203e-10 -16.28699069921748 -9.991999999999587e-10 3.4635241012353085e-11 -3.4662971389466093 -9.985999999999587e-10 5.09760699931052e-11 -5.104753654426927 -9.989999999999588e-10 3.7406949300510186e-11 -3.7444393694205935 -9.979999999999591e-10 5.6538830266161824e-11 -5.665213453523461 -9.987999999999587e-10 4.8979993956328746e-11 -4.903884056500877 +r_0230 biotin-[acetyl-CoA-carboxylase] ligase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0231 C-14 sterol reductase 0.0008494317939844 0.0001315502968727 15.486858133211443 0.0013737377811944 0.0001083457883188 7.886933722143284 0.0031840523609845 0.0001496341577181 4.699487971732499 0.0047307602081652 0.0002091516005982 4.421099176349295 0.0066938694774203 0.0004941875601284 7.3826889185015965 0.007921328546793 0.0004747121300081 5.992834752452945 0.0088775755234665 0.0006709423369801 7.557720406958422 0.0104560440838555 0.0010716366378225 10.248968244856204 0.0118256946200524 0.0009501315402669 8.034467071860737 +r_0233 C-22 sterol desaturase (NADP) 1.401020655969415e-06 4.00209692703016e-05 2856.5581170971163 2.420143304001588e-06 6.771713496248679e-05 2798.0630258761885 4.365646951675046e-06 0.0001277948058417 2927.2821933689684 6.849899676746246e-06 0.000200442189891 2926.206212501419 9.637281979221144e-06 0.0002860038190799 2967.681341031362 1.2625686015347656e-05 0.0003432654561259 2718.7865729326254 1.485764334343636e-05 0.0004105738412859 2763.3846889141355 2.448287862427815e-05 0.000619255010474 2529.33905353763 1.5456845302785002e-05 0.0005083674141516 3288.946768846947 +r_0234 C-3 sterol dehydrogenase 0.0008458125968607 0.0001003940630805 11.869539831063978 0.0013727847746864 0.0001010490570846 7.360881250139418 0.0031826697003636 0.0001408046931674 4.424106376836887 0.0047276145470325 0.0001843037371922 3.898451012845341 0.0066812781854429 0.0004140209234887 6.196732301774508 0.0079125417222542 0.0004139214410336 5.231207057897237 0.0088600529571935 0.0005437240826171 6.136803981241947 0.0104271310982037 0.0008792509059088 8.432337693158264 0.011808833839431 0.0008393746052033 7.108022829490808 +r_0235 C-3 sterol dehydrogenase (4-methylzymosterol) 0.0008458125943196 0.0001003940633159 11.86953989455217 0.0013727847793273 0.0001010490566346 7.360881192470453 0.0031826697081211 0.0001408046923259 4.42410633961432 0.0047276145476992 0.000184303737123 3.898451010833495 0.0066812781887402 0.0004140209231346 6.196732293416569 0.0079125417238871 0.0004139214408584 5.231207054604208 0.0088600529631083 0.0005437240820206 6.136803970411711 0.0104271311170102 0.0008792509040145 8.43233765978241 0.0118088338444952 0.0008393746046963 7.108022822148572 +r_0236 C-3 sterol keto reductase (4-methylzymosterol) 0.0008458125943196 0.0001003940633159 11.86953989455217 0.0013727847793273 0.0001010490566346 7.360881192470453 0.0031826697081211 0.0001408046923259 4.42410633961432 0.0047276145476992 0.000184303737123 3.898451010833495 0.0066812781887402 0.0004140209231346 6.196732293416569 0.0079125417238871 0.0004139214408584 5.231207054604208 0.0088600529631083 0.0005437240820206 6.136803970411711 0.0104271311170102 0.0008792509040145 8.43233765978241 0.0118088338444952 0.0008393746046963 7.108022822148572 +r_0237 C-3 sterol keto reductase (zymosterol) 0.0008458125968607 0.0001003940630805 11.869539831063978 0.0013727847746864 0.0001010490570846 7.360881250139418 0.0031826697003636 0.0001408046931674 4.424106376836887 0.0047276145470325 0.0001843037371922 3.898451012845341 0.0066812781854429 0.0004140209234887 6.196732301774508 0.0079125417222542 0.0004139214410336 5.231207057897237 0.0088600529571935 0.0005437240826171 6.136803981241947 0.0104271310982037 0.0008792509059088 8.432337693158264 0.011808833839431 0.0008393746052033 7.108022829490808 +r_0238 C-4 methyl sterol oxidase 0.0008458125968607 0.0001003940630805 11.869539831063978 0.0013727847746864 0.0001010490570846 7.360881250139418 0.0031826697003636 0.0001408046931674 4.424106376836887 0.0047276145470325 0.0001843037371922 3.898451012845341 0.0066812781854429 0.0004140209234887 6.196732301774508 0.0079125417222542 0.0004139214410336 5.231207057897237 0.0088600529571935 0.0005437240826171 6.136803981241947 0.0104271310982037 0.0008792509059088 8.432337693158264 0.011808833839431 0.0008393746052033 7.108022829490808 +r_0239 C-4 methyl sterol oxidase 0.0008458125968607 0.0001003940630805 11.869539831063978 0.0013727847746864 0.0001010490570846 7.360881250139418 0.0031826697003636 0.0001408046931674 4.424106376836887 0.0047276145470325 0.0001843037371922 3.898451012845341 0.0066812781854429 0.0004140209234887 6.196732301774508 0.0079125417222542 0.0004139214410336 5.231207057897237 0.0088600529571935 0.0005437240826171 6.136803981241947 0.0104271310982037 0.0008792509059088 8.432337693158264 0.011808833839431 0.0008393746052033 7.108022829490808 +r_0240 C-4 methyl sterol oxidase 0.0008458125968607 0.0001003940630805 11.86953983106398 0.0013727847746864 0.0001010490570846 7.360881250139418 0.0031826697003636 0.0001408046931674 4.424106376836887 0.0047276145470325 0.0001843037371922 3.898451012845341 0.0066812781854429 0.0004140209234887 6.196732301774508 0.0079125417222542 0.0004139214410336 5.231207057897237 0.0088600529571935 0.0005437240826171 6.136803981241947 0.0104271310982037 0.0008792509059088 8.432337693158264 0.011808833839431 0.0008393746052033 7.108022829490808 +r_0241 C-4 sterol methyl oxidase (4,4-dimethylzymosterol) 0.0008458125943196 0.0001003940633159 11.86953989455217 0.0013727847793273 0.0001010490566346 7.360881192470453 0.0031826697081211 0.0001408046923259 4.42410633961432 0.0047276145476992 0.000184303737123 3.898451010833495 0.0066812781887402 0.0004140209231346 6.196732293416569 0.0079125417238871 0.0004139214408584 5.231207054604205 0.0088600529631083 0.0005437240820206 6.136803970411711 0.0104271311170102 0.0008792509040145 8.43233765978241 0.0118088338444952 0.0008393746046963 7.108022822148572 +r_0242 C-5 sterol desaturase 1.401020655969415e-06 4.00209692703016e-05 2856.5581170971163 2.420143304001588e-06 6.771713496248679e-05 2798.0630258761885 4.365646951675046e-06 0.0001277948058417 2927.2821933689684 6.849899676746246e-06 0.000200442189891 2926.206212501419 9.637281979221146e-06 0.0002860038190799 2967.6813410313616 1.2625686015347656e-05 0.0003432654561259 2718.7865729326254 1.485764334343636e-05 0.0004105738412859 2763.3846889141355 2.448287862427815e-05 0.000619255010474 2529.33905353763 1.5456845302785002e-05 0.0005083674141516 3288.946768846947 +r_0243 C-8 sterol isomerase 1.6411918209835046e-06 4.798193229042523e-05 2923.6029376305 2.679301447964754e-06 7.017198052258797e-05 2619.040144806844 5.570628939280229e-06 0.0001467064390379 2633.570475381675 8.205702305328827e-06 0.0002156927677147 2628.571689405444 1.0569012282171175e-05 0.0002934872157307 2776.865121311744 1.9895901301131583e-05 0.0004210501788121 2116.265920500079 2.0479758932281028e-05 0.0004559719954707 2226.451966443769 2.8634547091228224e-05 0.0006846138919969 2390.8668428236624 2.33949746240946e-05 0.0006543714469431 2797.059870581158 +r_0244 C-s24 sterol reductase 0.0008398668803714 4.839332147879687e-05 5.762022840737752 0.0013685772518619 6.842335384850992e-05 4.9995974838409785 0.0031749275688206 8.756256768669548e-05 2.757939064393211 0.0047196905617361 0.0001303944125048 2.762774609887368 0.0066561144929401 0.0002330114516317 3.500712793911908 0.0078839868969702 0.0001928268149889 2.4458033417468217 0.0088298845839995 0.0003035071160198 3.437271610206653 0.010376551751775 0.000482226161875 4.647267930722303 0.0117597368091258 0.0004446597166924 3.781204663928735 +r_0249 CAAX farnesyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0250 carbamoyl-phosphate synthase (glutamine-hydrolysing) 0.0053371780383484 0.0007414033853027 13.891299484028403 0.0090086822602656 0.0022670926356255 25.1656409908576 0.022652162471954 0.0013805089115295 6.094380230756399 0.0364068165041666 0.0033221941139473 9.125198061651934 0.0438339566724865 0.0046013910606668 10.497320821496968 0.0569130617384452 0.0030557691501881 5.369187769639784 0.0650433147299585 0.0054894753829655 8.439722676736665 0.080330641276592 0.0109851672064859 13.67494026178902 0.0870763105835264 0.0103560629469992 11.893088806358412 +r_0252 carnitine O-acetyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0253 carnitine O-acetyltransferase 5.796483430817733e-05 0.0010550828374742 1820.2119441328048 0.0001566160572167 0.0023321676033414 1489.0986561572197 0.0001239357665348 0.0019093886344443 1540.6276072113735 0.0002160273622852 0.0030707022543615 1421.4413497800886 0.0003562419667273 0.0055967068123597 1571.0408472571978 0.0002891124770911 0.0043961849959788 1520.5794783437889 0.0006392191695451 0.0092307551334507 1444.067320449606 0.0007962591426857 0.0124551430321347 1564.2072240608095 0.0007126960586896 0.0117362012769891 1646.733012466381 +r_0254 carnitine O-acetyltransferase 5.796567490818072e-05 0.0010550828305337 1820.1855360177904 0.0001566168074167 0.0023321676051072 1489.0915244498954 0.0001239359277348 0.0019093886303418 1540.6256000498722 0.0002160278372852 0.003070702239063 1421.4382172462442 0.0003562421677273 0.0055967068099239 1571.0399601561453 0.0002891132796911 0.0043961849984899 1520.5752579703144 0.0006392194327451 0.0092307551294024 1444.066725218378 0.0007962593098857 0.0124551430158856 1564.2068935650188 0.0007126963612896 0.0117362012673241 1646.7323119325235 +r_0255 catalase 5.271675220836196e-05 0.0007349584939128 1394.1649724701003 9.480790898275116e-05 0.0014455144485802 1524.6770697613415 6.37395827894481e-05 0.0008554706312631 1342.1340301035057 0.0001222554499907 0.0017840094614017 1459.2473885923705 0.0002640894061495 0.0036316311728308 1375.15215993709 0.0002059013204444 0.0026917047787287 1307.2790271174845 0.0002505043521861 0.003711278145052 1481.5224217320972 0.0005538985074661 0.0082153181924962 1483.181139100239 0.0005076009881694 0.0072396256887249 1426.2434190352133 +r_0256 catalase 0.0004881662589254 0.0019451412976744 398.4587754909584 0.001031715104984 0.0037642506306314 364.8536899815595 0.0008036680883062 0.0031535719285669 392.39730610842713 0.0012843388433245 0.0047864364245369 372.6770742327595 0.0024099456667058 0.0094312711008375 391.3478727397663 0.0019907257428154 0.0073995283862245 371.7000401953719 0.0036690464018228 0.0141308096835283 385.1357583405893 0.0058412741192619 0.0218537670161023 374.12671567729205 0.0052769658422763 0.0205550001188705 389.52308453835866 +r_0259 ceramide-1 hydroxylase (24C) 9.209922978508735e-11 2.215975378486758e-09 2406.0737355325496 2.9529289312469795e-10 2.156155105867725e-09 730.1750756856894 5.171837928465634e-11 1.854200118622001e-09 3585.186048496496 1.7985729248561396e-10 2.031845151892954e-09 1129.698509197492 1.038497366323578e-10 2.0112532742631528e-09 1936.6955945042616 2.0986099510505367e-10 2.212388417724886e-09 1054.216109390596 9.03077771418134e-11 2.1756839295061856e-09 2409.1877780245154 1.244925942285408e-10 1.881785211707989e-09 1511.5639796640824 7.047615127324461e-11 2.571957164944361e-09 3649.400709997018 +r_0260 ceramide-1 hydroxylase (24C) -1.173070893081098e-11 2.246129553211056e-09 -19147.43232023722 2.122507445761476e-10 2.2508082228482797e-09 1060.447739461651 -1.1058270319412108e-11 2.034226398638034e-09 -18395.52063641522 1.6178687816711314e-10 2.140498320396096e-09 1323.0358015717009 5.717388903983102e-11 2.2349293463291127e-09 3909.003539661464 1.0654871597860962e-10 1.9132324314136648e-09 1795.6410021851032 -3.2259226177211665e-11 1.9109764731240475e-09 -5923.813741304142 4.700409860782949e-11 1.606300032593993e-09 3417.361634771209 7.552619713316881e-11 2.1257677464094727e-09 2814.6098004395617 +r_0261 ceramide-1 hydroxylase (26C) 3.6040852761434126e-11 2.456892497732999e-09 6816.965497448 3.494510168667789e-11 2.091665994347129e-09 5985.577072006444 3.753694282754457e-11 1.7214231007545591e-09 4585.943795858038 -3.1962234994039294e-11 2.728496177383385e-09 -8536.625107387605 -2.223341607187883e-11 2.026274163509426e-09 -9113.64298207098 8.399167716848916e-11 2.107568714852215e-09 2509.258995536409 1.0805151402767211e-10 1.6270358866279566e-09 1505.7964724226547 6.326267768273855e-11 1.926209004116418e-09 3044.779441326101 -9.51676209913896e-13 1.9377533423717914e-09 -203614.77172442 +r_0262 ceramide-1 hydroxylase (26C) 2.771786189088405e-11 2.2712021778903527e-09 8194.002072855821 -1.1963968081160727e-10 2.216271243672409e-09 -1852.4549953976395 -6.921330152064813e-11 1.848640094506194e-09 -2670.9318207493634 -2.2346102283930923e-10 2.370808475614298e-09 -1060.9494423191404 -6.940720687276921e-11 2.022930665643883e-09 -2914.583019241978 -1.5120134503035903e-11 1.986302911966784e-09 -13136.807159803797 -3.8244336046288585e-11 1.93030057662886e-09 -5047.2848431530965 7.803235777582793e-12 1.5156394122817606e-09 19423.216925418343 -1.6239711429201986e-10 1.8082329073323727e-09 -1113.4636937457135 +r_0263 ceramide-1 synthase (24C) 0.0001328276657675 0.0024187135761176 1820.9411135410107 -1.4320187943800742e-10 4.126017153286949e-09 -2881.259079475361 -9.473191356582943e-10 4.569638592919586e-09 -482.3758352293953 -5.097581949110053e-10 4.688473869275895e-09 -919.7446781791152 -5.172791649378104e-10 3.522787469170407e-09 -681.0224938392661 -4.5727907786463535e-10 4.0566512430902295e-09 -887.1281104820383 -1.2213183737846535e-09 5.275409036172054e-09 -431.9438034674347 -5.238670169806875e-10 3.567592457982129e-09 -681.011085321611 -6.770016560945804e-10 4.18496382506827e-09 -618.1615343764552 +r_0264 ceramide-1 synthase (26C) 1.3464754987290268e-05 0.0002342690530104 1739.868666244499 0.0001686943059973 0.0036069974998567 2138.185683583816 0.000182255663525 0.0031069366754866 1704.7133764708856 0.0005124673758881 0.0065647780620733 1281.0138500419982 0.0004335054807057 0.0087857053236831 2026.6653398201104 3.52150638911313e-05 0.0007333545871401 2082.5025034948594 0.0008784150556381 0.015975470042111 1818.6698804365365 0.0008738497441357 0.0191451213549842 2190.893970441009 0.001069344812275 0.0208449083966375 1949.315894869328 +r_0265 ceramide-2 synthase (24C) -7.78926257442882e-10 4.642400573967593e-09 -596.0000102202252 -7.690586569747032e-10 5.035724198822415e-09 -654.790652592323 -1.2097262226385372e-09 5.554871425907942e-09 -459.1841791932224 -8.081200070182322e-10 4.524335321356383e-09 -559.859337977547 -9.719860824250423e-10 4.957247551370761e-09 -510.0121947222485 -8.497432071734743e-10 5.121349832667821e-09 -602.6938243734971 -1.577219250738791e-09 5.8455674988452684e-09 -370.6249144567011 -1.091374585470749e-09 5.217067391568849e-09 -478.0272017529656 -1.1333811630555283e-09 5.404293190869081e-09 -476.8292757133379 +r_0266 ceramide-2 synthase (26C) -8.322233089336161e-10 4.566761810666084e-09 -548.7423581679998 -1.298693370138517e-09 5.157683639710297e-09 -397.1440648195644 -9.229614888653567e-10 5.254543433425538e-09 -569.3134000515247 -1.502883476940332e-09 5.4847838512825085e-09 -364.9507054564728 -1.373085636605851e-09 4.992506356317999e-09 -363.5975953152524 -5.505873217558438e-10 4.504584377982218e-09 -818.1416825249313 -1.324265137208371e-09 4.7886490618061286e-09 -361.6080290311714 -1.357694541423978e-09 5.127418810945401e-09 -377.65628825226463 -1.36226968013768e-09 5.2420800973949235e-09 -384.8048718859488 +r_0267 ceramide-3 synthase (24C) -2.7321534030211147e-10 3.2680131986788862e-09 -1196.1309328624216 9.640096293447506e-12 2.7969695039584835e-09 29013.916654127395 -1.3963328443698956e-10 2.530413929344713e-09 -1812.1853536193075 -1.5480485216552226e-10 2.675578602957445e-09 -1728.3557753710663 5.746982671647413e-12 2.5955258868979107e-09 45163.28019750032 -4.5913509636698984e-10 3.315248239923586e-09 -722.0637816965499 -1.5943438420785594e-10 2.2875331584427273e-09 -1434.7803140509836 -9.710666746741091e-11 2.0636027413359004e-09 -2125.088621776097 -7.313023804701182e-11 2.219357720355942e-09 -3034.8017176277017 +r_0268 ceramide-3 synthase (26C) -1.0583081255637378e-10 2.948196833608184e-09 -2785.7641478824926 -1.9739966760025559e-10 2.8099570008622803e-09 -1423.4861866903375 -2.693444969278272e-10 2.879345142829237e-09 -1069.0194808772274 -5.740244201504317e-10 3.259835789605428e-09 -567.8914825176148 -2.205737123289924e-10 2.716230860577012e-09 -1231.4390649261377 -1.5782783165661332e-10 2.824746361400682e-09 -1789.764410846431 -1.7111559959908292e-10 2.229761724070512e-09 -1303.0733196124463 -4.0257505218353694e-10 2.557159080534605e-09 -635.200583509774 -1.387419522036386e-10 2.1429987773640886e-09 -1544.5932130309805 +r_0269 ceramide-4 synthase (24C) -5.0092377449900886e-11 2.507954917909601e-09 -5006.65978654715 -3.914582595285968e-11 2.419032442585609e-09 -6179.541199357153 -1.2421453836787436e-10 2.344860605266574e-09 -1887.7505291063628 -1.1770746957917303e-10 2.627795940810894e-09 -2232.4801902596096 -2.2451308328460486e-10 2.763043474658098e-09 -1230.6826106679564 -1.7479540043973114e-10 2.6074519982260433e-09 -1491.7165964702167 -6.870249566429463e-11 1.9784528470029203e-09 -2879.739415392361 -2.525719071352145e-11 1.8117482825894991e-09 -7173.19793455722 1.9173494431514733e-11 2.1273812567772282e-09 11095.427932430166 +r_0270 ceramide-4 synthase (26C) -2.1332625305965968e-10 3.385818067857096e-09 -1587.1548950471674 -6.681434206492569e-11 2.8883563723149997e-09 -4322.958638892664 -9.621599975137154e-12 2.3522807856613964e-09 -24447.917100480645 -1.0567656038074768e-10 3.077303280027755e-09 -2912.001742808789 -2.0349674515420528e-10 2.97484996359464e-09 -1461.8661155196191 -2.5737557840836975e-11 2.8042489207733124e-09 -10895.551699640668 4.836563511144752e-11 2.176535728296446e-09 4500.16984844946 -1.8380404393780701e-10 2.2848709854161123e-09 -1243.1015860506498 8.699515907182005e-11 1.9565282911767555e-09 2249.0082345404035 +r_0271 chitin deacetylase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0272 chitin synthase 0.0007085721152914 5.235247215655345e-06 0.73884465711746 0.0011247273276555 6.938851760166812e-06 0.6169363533320047 0.0022993745103672 6.478485578502098e-06 0.2817499084769463 0.0030401707744782 8.230594227139367e-06 0.2707280227885172 0.0053857103470881 2.2676278161628328e-05 0.4210452605177442 0.0056201898509361 1.6369253792784638e-05 0.291258022005395 0.006100548845254 2.882280044957436e-05 0.4724624157709529 0.0066801211360368 3.921452493044668e-05 0.5870331410443833 0.0081236580654794 4.089939732682069e-05 0.5034603499698964 +r_0273 choline kinase 0.0004587585740576 0.0031935047376968 696.1188124400688 0.0008975483505137 0.0061292380298193 682.8866685913163 0.0008158535616323 0.0051038976437142 625.5899200222439 0.0009962545635309 0.0068715049185989 689.7338461612566 0.0023162225930047 0.0153237042434951 661.5816756893156 0.0020217915490471 0.0128015342685259 633.1777514135441 0.0034225681500185 0.0226557092467575 661.9505661745527 0.0054218017929106 0.0359116885448399 662.3570893313924 0.0051793965212195 0.0343054183777787 662.3439282401395 +r_0274 choline phosphate cytididyltransferase 0.0004587592491787 0.0031935047598895 696.1177928524874 0.0008975491323137 0.0061292380440593 682.8860753571378 0.000814507083641 0.0051032237778334 626.5413622949228 0.0009962552395309 0.0068715049332203 689.7333796162092 0.0023122502188938 0.0153217285201273 662.632806559184 0.0020156500326128 0.0127988183022561 634.9722469264941 0.0034225687369787 0.0226557092729779 661.9504534181384 0.0054218022941505 0.0359116885864846 662.3570288652716 0.0051706899899171 0.0343012058308998 663.3777290417171 +r_0278 chorismate mutase 0.0044829944369184 0.0017771768713631 39.64262941590356 0.0073652990850466 0.0014213055393386 19.297322796085865 0.0202409437106811 0.0025080296224106 12.390872966496998 0.033787846482262 0.0031894605039825 9.43966791626373 0.0367813669651378 0.006511544052356 17.703376980327626 0.0511608958960878 0.0062634026858131 12.242558649744298 0.0596370684828776 0.0101584756230202 17.033827921868504 0.0754316795870143 0.0154354103189383 20.462768963181887 0.0793411530495421 0.0137999625564904 17.3931963754969 +r_0279 chorismate synthase 0.0052205259442072 0.0018452916334718 35.34685304110687 0.0085911211558188 0.0015329995362894 17.843998571142254 0.0234777578226843 0.0026533896684269 11.301716665052377 0.0391133977095598 0.0034503658296924 8.821442349021886 0.0428365307734951 0.0069640715401313 16.257319195513272 0.0593364683675767 0.006629716167228 11.173088573722188 0.0691322083053571 0.0108932693696886 15.757155219999644 0.0873769259750843 0.0165973939258096 18.99516804990648 0.0920948624104587 0.0151617995402077 16.46324142668555 +r_0280 cis-aconitate(3-) to isocitrate 0.00710147640254 0.0426344256538738 600.3600270871024 0.0149187871087403 0.1526813710940087 1023.4167830209112 0.0015874205939363 0.0396720970104392 2499.1547395806265 0.0104992110265327 0.2377638691298257 2264.5879631237767 0.0181147789635777 0.4273010781977019 2358.853392894548 0.0036474712402428 0.0807059465858491 2212.6547755994266 0.0064944929487623 0.1480643546477708 2279.844720995312 0.0081086516627366 0.1812949217318262 2235.820815499665 0.0051752920616753 0.135217837626004 2612.757618595743 +r_0281 cis-prenyltransferase step 01 1.7799999999999986e-11 1.3223712539020804e-10 742.9051988213942 4e-13 1.9997999499871765e-11 4999.499874967941 2.3544999999733353e-10 4.5933973930758894e-10 195.0901419888685 2.6200000001064517e-11 2.3403955840895604e-10 893.2807572497973 1.263e-10 3.339095822551573e-10 264.37813321865195 2.3999999995692896e-12 6.815547692508196e-11 2839.8115390547227 2.0083333321044343e-10 4.020101782707662e-10 200.17104324485783 7.835000001560079e-11 3.74568869269893e-10 478.0713072052457 2.962000000000058e-10 4.566259535465685e-10 154.1613617645373 +r_0282 cis-prenyltransferase step 02 1.7799999999999986e-11 1.3223712539020804e-10 742.9051988213942 4e-13 1.9997999499871765e-11 4999.499874967941 2.3544999999733353e-10 4.5933973930758894e-10 195.0901419888685 2.6200000001064517e-11 2.3403955840895604e-10 893.2807572497973 1.263e-10 3.339095822551573e-10 264.37813321865195 2.3999999995692896e-12 6.815547692508196e-11 2839.8115390547227 2.0083333321044343e-10 4.020101782707662e-10 200.17104324485783 7.835000001540255e-11 3.7456886927060714e-10 478.071307207367 2.962000000000058e-10 4.566259535465685e-10 154.1613617645373 +r_0283 cis-prenyltransferase step 03 1.7799999999999986e-11 1.3223712539020804e-10 742.9051988213942 4e-13 1.9997999499871765e-11 4999.499874967941 2.3544999999733353e-10 4.5933973930758894e-10 195.0901419888685 2.6200000001064517e-11 2.3403955840895604e-10 893.2807572497973 1.263e-10 3.339095822551573e-10 264.37813321865195 2.3999999995692896e-12 6.815547692508196e-11 2839.8115390547227 2.0083333321044343e-10 4.020101782707662e-10 200.17104324485783 7.835000001540255e-11 3.7456886927060714e-10 478.071307207367 2.962000000000058e-10 4.566259535465685e-10 154.1613617645373 +r_0284 cis-prenyltransferase step 04 1.7799999999999986e-11 1.3223712539020804e-10 742.9051988213942 4e-13 1.9997999499871765e-11 4999.499874967941 2.3544999999733353e-10 4.5933973930758894e-10 195.0901419888685 2.6200000001064517e-11 2.3403955840895604e-10 893.2807572497973 1.263e-10 3.339095822551573e-10 264.37813321865195 2.3999999995692896e-12 6.815547692508196e-11 2839.8115390547227 2.0083333321044343e-10 4.020101782707662e-10 200.17104324485783 7.835000001540255e-11 3.7456886927060714e-10 478.071307207367 2.962000000000058e-10 4.566259535465685e-10 154.1613617645373 +r_0285 cis-prenyltransferase step 05 1.7799999999999986e-11 1.3223712539020804e-10 742.9051988213942 4e-13 1.9997999499871765e-11 4999.499874967941 2.3544999999733353e-10 4.5933973930758894e-10 195.0901419888685 2.6200000001064517e-11 2.3403955840895604e-10 893.2807572497973 1.263e-10 3.339095822551573e-10 264.37813321865195 2.3999999995692896e-12 6.815547692508196e-11 2839.8115390547227 2.0083333321044343e-10 4.020101782707662e-10 200.17104324485783 7.835000001540255e-11 3.7456886927060714e-10 478.071307207367 2.962000000000058e-10 4.566259535465685e-10 154.1613617645373 +r_0286 cis-prenyltransferase step 06 1.7799999999999986e-11 1.3223712539020804e-10 742.9051988213942 4e-13 1.9997999499871765e-11 4999.499874967941 2.3544999999733353e-10 4.5933973930758894e-10 195.0901419888685 2.6200000001064517e-11 2.3403955840895604e-10 893.2807572497973 1.263e-10 3.339095822551573e-10 264.37813321865195 2.3999999995692896e-12 6.815547692508196e-11 2839.8115390547227 2.0083333321044343e-10 4.020101782707662e-10 200.17104324485783 7.835000001540255e-11 3.7456886927060714e-10 478.071307207367 2.962000000000058e-10 4.566259535465685e-10 154.1613617645373 +r_0287 cis-prenyltransferase step 07 1.7799999999999986e-11 1.3223712539020804e-10 742.9051988213942 4e-13 1.9997999499871765e-11 4999.499874967941 2.3544999999733353e-10 4.5933973930758894e-10 195.0901419888685 2.6200000001064517e-11 2.3403955840895604e-10 893.2807572497973 1.263e-10 3.339095822551573e-10 264.37813321865195 2.3999999995692896e-12 6.815547692508196e-11 2839.8115390547227 2.0083333321044343e-10 4.020101782707662e-10 200.17104324485783 7.835000001609644e-11 3.7456886926813935e-10 478.0713071999834 2.962000000000058e-10 4.566259535465685e-10 154.1613617645373 +r_0288 cis-prenyltransferase step 08 1.7799999999999986e-11 1.3223712539020804e-10 742.9051988213942 4e-13 1.9997999499871765e-11 4999.499874967941 2.3544999999733353e-10 4.5933973930758894e-10 195.0901419888685 2.6200000001064517e-11 2.3403955840895604e-10 893.2807572497973 1.263e-10 3.339095822551573e-10 264.37813321865195 2.3999999995692896e-12 6.815547692508196e-11 2839.8115390547227 2.0083333321044343e-10 4.020101782707662e-10 200.17104324485783 7.835000001609644e-11 3.7456886926813935e-10 478.0713071999834 2.962000000000058e-10 4.566259535465685e-10 154.1613617645373 +r_0289 cis-prenyltransferase step 09 -1.423999999999999e-11 1.0578970031216588e-10 -742.9051988213902 -3.2000000000000005e-13 1.5998399599894867e-11 -4999.499874967145 -1.7275999999999584e-10 3.8046147319604844e-10 -220.22544176664604 1.4280000000000011e-11 2.11898706490535e-10 1483.8844992334373 -1.0104000000000024e-10 2.6712766580413425e-10 -264.3781332186596 -1.56e-12 5.519217005270527e-11 -3537.9596187631582 -1.5866666656835268e-10 3.234666966549606e-10 -203.8655652449931 -4.984000000000035e-11 3.093979958305546e-10 -620.7824956471758 -2.369599999999986e-10 3.653007628372402e-10 -154.16136176453514 +r_0290 cis-prenyltransferase step 10 -1.423999999999999e-11 1.0578970031216588e-10 -742.9051988213902 -3.2000000000000005e-13 1.5998399599894867e-11 -4999.499874967145 -1.7275999999999584e-10 3.8046147319604844e-10 -220.22544176664604 1.4280000000000011e-11 2.11898706490535e-10 1483.8844992334373 -1.0104000000000024e-10 2.6712766580413425e-10 -264.3781332186596 -1.56e-12 5.519217005270528e-11 -3537.9596187631582 -1.5866666656835268e-10 3.234666966549606e-10 -203.8655652449931 -4.984000000000035e-11 3.093979958305546e-10 -620.7824956471758 -2.369599999999986e-10 3.653007628372402e-10 -154.16136176453514 +r_0291 cis-prenyltransferase step 11 -1.423999999999999e-11 1.0578970031216588e-10 -742.9051988213902 -3.2000000000000005e-13 1.5998399599894867e-11 -4999.499874967145 -1.7275999999999584e-10 3.8046147319604844e-10 -220.22544176664604 1.4280000000000011e-11 2.11898706490535e-10 1483.8844992334373 -1.0104000000000024e-10 2.6712766580413425e-10 -264.3781332186596 -1.56e-12 5.519217005270528e-11 -3537.9596187631582 -1.5866666656835268e-10 3.234666966549606e-10 -203.8655652449931 -4.984000000000035e-11 3.093979958305546e-10 -620.7824956471758 -2.369599999999986e-10 3.653007628372402e-10 -154.16136176453514 +r_0292 cis-prenyltransferase step 12 -1.423999999999999e-11 1.0578970031216588e-10 -742.9051988213902 -3.2000000000000005e-13 1.5998399599894867e-11 -4999.499874967145 -1.7275999999999584e-10 3.8046147319604844e-10 -220.22544176664604 1.4280000000000011e-11 2.11898706490535e-10 1483.8844992334373 -1.0104000000000024e-10 2.6712766580413425e-10 -264.3781332186596 -1.56e-12 5.519217005270528e-11 -3537.9596187631582 -1.5866666656835268e-10 3.234666966549606e-10 -203.8655652449931 -4.984000000000035e-11 3.093979958305546e-10 -620.7824956471758 -2.369599999999986e-10 3.653007628372402e-10 -154.16136176453514 +r_0293 cis-prenyltransferase step 13 -1.423999999999999e-11 1.0578970031216588e-10 -742.9051988213902 -3.2000000000000005e-13 1.5998399599894867e-11 -4999.499874967145 -1.7275999999999584e-10 3.8046147319604844e-10 -220.22544176664604 1.4280000000000011e-11 2.11898706490535e-10 1483.8844992334373 -1.0104000000000024e-10 2.6712766580413425e-10 -264.3781332186596 -1.56e-12 5.519217005270528e-11 -3537.9596187631582 -1.5866666656835268e-10 3.234666966549606e-10 -203.8655652449931 -4.984000000000035e-11 3.093979958305546e-10 -620.7824956471758 -2.369599999999986e-10 3.653007628372402e-10 -154.16136176453514 +r_0294 cis-prenyltransferase step 14 -1.423999999999999e-11 1.0578970031216588e-10 -742.9051988213902 -3.2e-13 1.5998399599894864e-11 -4999.499874967146 -1.7275999999999584e-10 3.8046147319604844e-10 -220.22544176664604 1.4280000000000011e-11 2.11898706490535e-10 1483.8844992334373 -1.0104000000000024e-10 2.671276658041341e-10 -264.37813321865946 -1.56e-12 5.519217005270527e-11 -3537.9596187631582 -1.5866666656835268e-10 3.234666966549606e-10 -203.8655652449931 -4.984000000000035e-11 3.093979958305546e-10 -620.7824956471758 -2.369599999999986e-10 3.653007628372402e-10 -154.16136176453514 +r_0295 cis-prenyltransferase step 15 -1.423999999999999e-11 1.0578970031216588e-10 -742.9051988213902 -3.2e-13 1.5998399599894864e-11 -4999.499874967146 -1.7275999999999584e-10 3.8046147319604844e-10 -220.22544176664604 1.4280000000000011e-11 2.11898706490535e-10 1483.8844992334373 -1.0104000000000024e-10 2.671276658041341e-10 -264.37813321865946 -1.56e-12 5.519217005270527e-11 -3537.9596187631582 -1.5866666656835268e-10 3.234666966549606e-10 -203.8655652449931 -4.984000000000035e-11 3.093979958305546e-10 -620.7824956471758 -2.369599999999986e-10 3.653007628372402e-10 -154.16136176453514 +r_0296 cis-prenyltransferase step 16 -1.423999999999999e-11 1.0578970031216588e-10 -742.9051988213902 -3.2e-13 1.5998399599894864e-11 -4999.499874967146 -1.7275999999999584e-10 3.8046147319604844e-10 -220.22544176664604 1.4280000000000011e-11 2.11898706490535e-10 1483.8844992334373 -1.0104000000000024e-10 2.671276658041341e-10 -264.37813321865946 -1.56e-12 5.519217005270527e-11 -3537.9596187631582 -1.5866666656835268e-10 3.234666966549606e-10 -203.8655652449931 -4.984000000000035e-11 3.093979958305546e-10 -620.7824956471758 -2.369599999999986e-10 3.653007628372402e-10 -154.16136176453514 +r_0297 cis-prenyltransferase step 17 -1.423999999999999e-11 1.0578970031216588e-10 -742.9051988213902 -3.2e-13 1.5998399599894864e-11 -4999.499874967146 -1.7275999999999584e-10 3.8046147319604844e-10 -220.22544176664604 1.4280000000000011e-11 2.11898706490535e-10 1483.8844992334373 -1.0104000000000024e-10 2.671276658041341e-10 -264.37813321865946 -1.56e-12 5.519217005270527e-11 -3537.9596187631582 -1.5866666656835268e-10 3.234666966549606e-10 -203.8655652449931 -4.984000000000035e-11 3.093979958305546e-10 -620.7824956471758 -2.369599999999986e-10 3.653007628372402e-10 -154.16136176453514 +r_0298 cis-prenyltransferase step 18 -1.423999999999999e-11 1.0578970031216588e-10 -742.9051988213902 -3.2e-13 1.5998399599894864e-11 -4999.499874967146 -1.7275999999999584e-10 3.8046147319604844e-10 -220.22544176664604 1.4280000000000011e-11 2.11898706490535e-10 1483.8844992334373 -1.0104000000000024e-10 2.6712766580413404e-10 -264.3781332186594 -1.5599999999999998e-12 5.519217005270527e-11 -3537.959618763159 -1.5866666656835268e-10 3.234666966549606e-10 -203.8655652449931 -4.984000000000035e-11 3.093979958305546e-10 -620.7824956471758 -2.369599999999986e-10 3.653007628372402e-10 -154.16136176453514 +r_0299 cis-prenyltransferase step 19 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0300 citrate synthase 0.27810572681335 0.0414582048219466 14.907353867535154 0.5282407569634029 0.0831469200761643 15.7403454731769 0.809198457269482 0.1154247492708229 14.264084197627655 1.326137716985741 0.1981124219049483 14.939053415602272 2.01757123219557 0.3610283694423278 17.89420684044191 1.862742676962717 0.2623546489066345 14.084320510357085 2.799454976161001 0.4103798298302313 14.659275942097874 3.192955480396556 0.5697228521935331 17.84311919447042 3.490909215194361 0.5432000945862961 15.560418822179331 +r_0301 citrate synthase, peroxisomal 0.0009613967498141 0.0038968081336701 405.3277831887238 0.0020279312713704 0.0076956928280048 379.4848936277925 0.0015672965740259 0.0064087798590582 408.9066463404373 0.0024434283434746 0.0096800143193628 396.1652628452906 0.0047706864384975 0.0195733694622375 410.2841323690535 0.0038624217416961 0.0147001006650586 380.5928416973768 0.0070753489676679 0.028600967202625 404.2340149344189 0.01151615461556 0.045022473835883 390.9505849726153 0.0105620748556738 0.042493973445776 402.3260015331989 +r_0302 citrate to cis-aconitate(3-) 0.00710147640254 0.0426344256538738 600.3600270871024 0.0149187871087403 0.1526813710940087 1023.4167830209112 0.0015874205933363 0.0396720970104642 2499.15474052681 0.0104992110265327 0.2377638691298257 2264.5879631237767 0.0181147789635777 0.4273010781977019 2358.853392894548 0.0036474712402428 0.0807059465858491 2212.654775599426 0.0064944929483623 0.1480643546477929 2279.8447211360703 0.0081086516627366 0.1812949217318262 2235.820815499665 0.0051752920616753 0.135217837626004 2612.757618595743 +r_0303 citrate to cis-aconitate(3-), cytoplasmic 6.490000000000322e-10 5.497812764094426e-10 84.71206108003315 -0.0388416247107048 0.2972959939891788 -765.4056600450173 0.0242027165782208 0.0962431406091974 397.6542893362778 -0.0407602460159973 0.4893678432067578 -1200.6008084806308 0.6125502683380195 0.7124893044045103 116.31523831303625 0.1397911827509559 0.3847509491992426 275.2326302902045 0.2205003122071088 0.4116626700236293 186.69482410390785 0.1943366772364246 0.4375951850888692 225.17375068449024 1.5106220465372169 0.7494174602591107 49.60985853324414 +r_0304 coproporphyrinogen oxidase (O2 required) 1.3958217504192468e-05 0.0001439643151369 1031.3946970215925 8.005753318949784e-06 0.0001060046104505 1324.1053805592123 1.4419801075164914e-05 0.0001678547888321 1164.057589679841 1.3930017012026926e-05 0.0002030935219423 1457.956022357854 4.532236219298812e-05 0.0005130161546369 1131.9272205020063 3.858790289326032e-05 0.0004661301034462 1207.9695150462333 4.060617428819309e-05 0.0005824694784026 1434.435744349492 9.34694012777442e-05 0.0011187944996471 1196.9633744872604 9.266277582557682e-05 0.0010814233914153 1167.0526614171088 +r_0306 CTP synthase (glutamine) 1.3224793862078316e-06 3.794997627432621e-05 2869.608151938503 6.824361287338576e-06 0.0004378689801789 6416.2631745677645 2.8752027399996844e-05 0.0008765516756017 3048.6604071677807 4.256207737282515e-05 0.0012969326155991 3047.1553449766643 7.784431565727016e-05 0.0024013222361882 3084.775318419716 5.699090212782093e-05 0.0018557126842435 3256.156009044152 0.0001130531980077 0.0035289875673384 3121.528297762127 1.0385337326061138e-05 0.0003676075429827 3539.678408522166 0.0001160069807563 0.0043820392437043 3777.3927182079688 +r_0307 CTP synthase (NH3) 0.0011771518469111 0.0009878072955338 83.91502745596264 0.001916065437408 0.0016378743148458 85.48112621150563 0.0042889416559239 0.0011933325795198 27.82347430330777 0.0063823831563353 0.0019478465440408 30.51911012436484 0.0090139640901565 0.0029385672002332 32.60016537499029 0.0106484449162453 0.0029066000940137 27.29600534984636 0.0119479384943243 0.0044332818644356 37.10499402504952 0.0144280919867544 0.0098107360278478 67.99745965616579 0.0159940481332311 0.0066587870528224 41.632906174562414 +r_0308 cystathionine b-lyase 5.422724544592778e-05 0.0017152338990134 3163.0481779197494 8.062925569584329e-05 0.0028498128618871 3534.465049060401 8.293062000711159e-05 0.0026252245063208 3165.567200746527 0.0001257952019746 0.0039764137498644 3161.021793714164 0.0002511512908926 0.0079389406522458 3161.0192502013915 0.0001993715181236 0.0063128839421934 3166.392071247088 0.0003758318696632 0.0118805723762598 3161.140215944554 0.0005729672223174 0.0181115620470583 3161.0118941537826 0.0006604990576206 0.0190574305468376 2885.3077573630603 +r_0309 cystathionine beta-synthase 0.000610540099587 0.0017295343621313 283.2794051203285 0.0010284542766221 0.0028758622913088 279.6295719391915 0.0026853625776423 0.0026692043069918 99.3982834651446 0.0044977906019413 0.0040786516503814 90.68122576940286 0.0049562326004547 0.0079910524040542 161.23239259031095 0.0067873044673682 0.0064450936428561 94.95807465014478 0.0080125842462112 0.0120411642459315 150.27816090202336 0.0101883515958014 0.018339295789716 180.00258056733685 0.0108056693449631 0.0191609235629836 177.32287516196394 +r_0310 cystathionine g-lyase 0.0005746394432961 0.0006440204058256 112.07382530714688 0.0009705176764932 0.0008152610664493 84.0027014649628 0.0026506498596626 0.0012417544713856 46.8471709629594 0.0044334417147562 0.001895573842476 42.75625945790281 0.0047983467155608 0.002804918835383 58.45594329994464 0.0067000891408495 0.0033242613934808 49.61518158338076 0.007805021974372 0.0048391343406367 62.00026542559658 0.0097850219974199 0.0060439948700023 61.76782097777593 0.0103486888606859 0.0061268036269369 59.20367023703119 +r_0311 cystathionine gamma-synthase 1.7662044318427717e-05 0.0006025183912718 3411.37401995546 1.815467834373761e-05 0.0006416164862685 3534.1660927301086 3.097327643481682e-05 0.0009279271312391 2995.8959401404472 5.620430322247445e-05 0.0016216300281867 2885.241761236374 7.122082210019377e-05 0.0023517783566148 3302.0938080528103 9.47803379337813e-05 0.0028022210754628 2956.542608468657 0.0001341104277244 0.0040023947777514 2984.402365769505 0.0001581278507463 0.0052453297554123 3317.1447854722346 0.0001554874561596 0.0051374976164806 3304.123524411942 +r_0312 cysteine synthase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0313 cysteinyl-tRNA synthetase 0.0005488240314841 4.055019624196061e-06 0.7388560616105272 0.0009329960886377 5.756036753263908e-06 0.616941145130449 0.0025763290915898 7.258951557215214e-06 0.2817556026095952 0.0043252786361127 1.171000632104276e-05 0.2707341493163721 0.0046577263655843 1.961114963092021e-05 0.4210455508040567 0.0065210865672823 1.8993474361639493e-05 0.2912624171703807 0.0075517176566321 3.567938159858568e-05 0.472467102464446 0.0095038687668295 5.579127162141952e-05 0.5870374790542429 0.0100560744548838 5.062864367895945e-05 0.503463293814127 +r_0314 cytidine deaminase 2.057482641154385e-05 0.0006486834943175 3152.8017847753254 4.247056821879203e-05 0.0012235875298722 2881.0246276168828 2.1848824359357488e-05 0.0007473110741456 3420.3720156942823 5.520825557600051e-05 0.0015134945417875 2741.427936812898 7.709400691985656e-05 0.002404165874551 3118.4860803127426 7.363967125289964e-05 0.0022852004215472 3103.219205989163 0.0001303728839145 0.0038131506294591 2924.8034675351805 0.0002105619800692 0.0065786717701946 3124.3398110296466 0.0001424299525085 0.0049618803877634 3483.7337936106323 +r_0315 cytidine kinase (GTP) 2.9528757531233e-05 0.0014762895837865 4999.497802184949 2.687683679857162e-05 0.0019004465072928 7070.945593545028 2.2708204321261696e-05 0.0016057101012794 7071.057132315906 3.35455388329275e-05 0.0023720258702303 7071.062062959183 6.697390920628434e-05 0.0047357644383176 7071.05870695287 5.472085643351925e-05 0.0038693480554534 7071.066331270585 0.0001006694844144 0.0071184054308925 7071.06574777286 0.0001527912837573 0.0108039736416473 7071.066736246565 0.000146777608801 0.0103787418454097 7071.066172961145 +r_0317 cytochrome P450 lanosterol 14-alpha-demethylase (NADP) 0.0008494317939844 0.0001315502968727 15.486858133211443 0.0013737377811944 0.0001083457883188 7.886933722143284 0.0031840523609845 0.0001496341577181 4.699487971732499 0.0047307602081652 0.0002091516005982 4.421099176349295 0.0066938694774203 0.0004941875601284 7.3826889185015965 0.007921328546793 0.0004747121300081 5.992834752452945 0.0088775755234665 0.0006709423369801 7.557720406958422 0.0104560440838555 0.0010716366378225 10.248968244856204 0.0118256946200524 0.0009501315402669 8.034467071860737 +r_0318 cytosine deaminase 2.618971971965192e-05 0.0007039346509592 2687.828119180116 3.4049817118507696e-05 0.0010828708660976 3180.254573258872 3.7031690955753074e-05 0.0010755600164999 2904.4312823442697 4.667946894831633e-05 0.0014845153822036 3180.231942756972 4.7770898661208896e-05 0.0020422000548413 4274.987726993912 5.975682750704693e-05 0.0021261039484898 3557.9264114031453 9.3477115244267e-05 0.0034200910668782 3658.7469114136734 0.0001990764434834 0.0063236045971769 3176.4705489639728 0.0001168674747748 0.0047962153659577 4103.977924738428 +r_0319 D-arabinono-1,4-lactone oxidase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0320 D-arabinose 1-dehydrogenase (NAD) -4.6e-12 8.820655349358355e-11 -1917.5337715996425 -3.2300000000000793e-10 4.676694804545175e-10 -144.7893128342124 -5.620000000000005e-11 2.4052677735779976e-10 -427.9835896046256 -2.1399999999999967e-10 4.1065524171195006e-10 -191.8949727625937 -4.992000000000212e-10 5.008488094285224e-10 -100.33029035026064 -1.3119999999999982e-10 3.3824464798187467e-10 -257.8084207178927 -2.5540000000000286e-10 4.3978349435191207e-10 -172.19400718555485 -1.2000000000000012e-11 1.1772328467363794e-10 -981.0273722803156 -3.6620000000001115e-10 4.842979133692255e-10 -132.24956673107891 +r_0321 D-arabinose 1-dehydrogenase (NADP) 4.6e-12 8.820655349358355e-11 1917.5337715996425 3.2300000000000793e-10 4.676694804545175e-10 144.7893128342124 5.620000000000005e-11 2.4052677735779976e-10 427.9835896046256 2.1399999999999967e-10 4.1065524171195006e-10 191.8949727625937 4.992000000000212e-10 5.008488094285224e-10 100.33029035026064 1.3119999999999982e-10 3.3824464798187467e-10 257.8084207178927 2.5540000000000286e-10 4.3978349435191207e-10 172.19400718555485 1.2000000000000012e-11 1.1772328467363794e-10 981.0273722803156 3.6620000000001115e-10 4.842979133692255e-10 132.24956673107891 +r_0322 D-fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase -2.1359999999999955e-10 4.3268057790533694e-10 -202.56581362609447 -3.0423333333333975e-10 4.852436433275624e-10 -159.4971984203633 -3.640370724023177e-10 7.476053254932635e-10 -205.36516255329164 -2.1226666666666627e-10 4.3802982219952573e-10 -206.358270508571 -2.0853333333333255e-10 4.226564390505305e-10 -202.6805174475057 -1.4849999999999923e-10 3.7205568815301585e-10 -250.5425509447931 -2.334000000000012e-10 4.342374378499402e-10 -186.0486023350206 -2.1866666666666666e-10 4.159026802658776e-10 -190.1993964630538 -1.6429999999999875e-10 3.7694021646060277e-10 -229.42192115678972 +r_0323 D-sorbitol dehydrogenase (D-fructose producing) -8.920000000000079e-11 6.63725444964449e-10 -744.0868217090173 9.957999999999599e-10 8.356887429749358e-11 8.392134394205357 9.775999999999663e-10 2.0274728430305567e-10 20.739288492539146 9.961999999999598e-10 8.358802181818645e-11 8.390686791627164 9.735999999999676e-10 2.1473765960467435e-10 22.056045563340334 -1.5399999999999997e-11 5.919737549801369e-10 -3843.985421948941 9.765999999999664e-10 1.9198909334227647e-10 19.65892825540477 9.155999999999875e-10 3.0609700925655687e-10 33.43130288953265 9.80199999999965e-10 1.903029244142255e-10 19.41470357215184 +r_0326 dCMP deaminase -7.237377134478078e-06 0.0025849781736308 -35717.057790401945 -3.7553320047197055e-05 0.00448617647401 -11946.151414500164 0.0001391165612023 0.004119112169369 2960.9071226100496 0.0002238814146736 0.0059202492247061 2644.368329249253 0.000317903688141 0.0102184208966956 3214.313415628418 0.0003232224184845 0.0101925397076718 3153.413601525458 0.0003976872323421 0.0139797480111552 3515.26196323199 -0.000669911075301 0.0351964062890579 -5253.892283127259 0.0001547329309651 0.0253999747510396 16415.364585031934 +r_0327 dCTP deaminase 2.754580117975423e-05 0.0010854819536349 3940.6439716582577 0.0001128275009556 0.0030136320700994 2671.008437282495 0.0001034235497131 0.0025554010663284 2470.8116027895617 0.0001298143796472 0.0034999889476731 2696.1488836467765 0.0002871377015626 0.0075205002304778 2619.1267080394687 0.0002781869184654 0.0065759923003169 2363.875460640744 0.0003202713440801 0.0095776379634221 2990.476088621232 0.0006544858213366 0.0171445853367953 2619.550306190048 0.0007171903248287 0.0176134482865776 2455.895970262045 +r_0328 deoxyadenosine deaminase 9.505999999999756e-10 2.3102015942945523e-10 24.302562532028315 8.34200000000016e-10 3.8566839126585536e-10 46.23212554133876 9.34599999999981e-10 2.667153302933255e-10 28.53791250731124 9.43599999999978e-10 2.3922894076015225e-10 25.352791517608924 9.615999999999715e-10 1.9832626316584622e-10 20.62461139411939 9.445999999999775e-10 2.398798625764344e-10 25.394861589714168 8.384000000000145e-10 3.968840427488816e-10 47.3382684576425 8.006000000000275e-10 4.148180984611757e-10 51.813402255953214 9.45799999999977e-10 2.3931948262301616e-10 25.30339211493149 +r_0329 deoxycytidine deaminase 7.381856224065729e-05 0.0023323701143987 3159.5984039826376 8.07066246782188e-05 0.0032898026776454 4076.2486236563886 9.082631738351876e-05 0.0032080282995721 3532.047089420196 0.0001340804928437 0.0047390198527108 3534.4588554233446 0.0001340634767524 0.0066895289626481 4989.822078834839 0.0002187131804191 0.0077303429448098 3534.465975024433 0.0002014920783817 0.0100564001779285 4990.965530105516 0.0012224870538356 0.0305256186069229 2497.0095602359124 0.0004405368056635 0.017962540805307 4077.421131306297 +r_0330 deoxyguanylate kinase (dGMP:ATP) -2.203687041602052e-05 0.0013689447194266 -6212.065023676916 3.470529849606888e-05 0.0039630628082538 11419.186637172152 -0.0001063417210931 0.0029767700508029 -2799.2494575070727 -0.0002529347798682 0.0027659903782424 -1093.5587346601487 -0.0001108536857273 0.0095611994278371 -8625.06227474877 -0.0004139045848581 0.004020347152875 -971.3222080525734 -0.0002313888391001 0.0111149237821746 -4803.569534901395 -0.0003985451759386 0.0112255925216095 -2816.642428345009 -0.0004996967026728 0.0107837700576819 -2158.063081065145 +r_0331 deoxyhypusine synthase, cytosolic/mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0332 deoxyribokinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0334 dephospho-CoA kinase 2.134971474948976e-05 0.0005251029880226 2459.5316339542314 4.633000944433224e-05 0.0009124221567688 1969.397735317048 2.6868404333342928e-05 0.0007129715476356 2653.56862577376 7.11128435787169e-05 0.0014544608006586 2045.2856719878969 0.0001057767290311 0.00250309285894 2366.392761305746 6.0742929545794445e-05 0.0017280435903137 2844.847298665401 0.000181062438238 0.0040083986064883 2213.8211798622424 0.0001937305576143 0.0051606827339713 2663.8454963023505 0.0002332445022886 0.0054467037244984 2335.19061373543 +r_0335 dethiobiotin synthase -9.987999999999587e-10 4.897999395632864e-11 -4.903884056500868 -9.851999999999635e-10 1.7025497746458775e-10 -17.281260400385108 -9.979999999999591e-10 6.322024485773655e-11 -6.334693873520955 -9.86799999999963e-10 1.6072002421987203e-10 -16.28699069921748 -9.991999999999587e-10 3.4635241012353085e-11 -3.4662971389466093 -9.985999999999587e-10 5.09760699931052e-11 -5.104753654426927 -9.989999999999588e-10 3.7406949300510186e-11 -3.7444393694205935 -9.979999999999591e-10 5.6538830266161824e-11 -5.665213453523461 -9.987999999999587e-10 4.8979993956328746e-11 -4.903884056500877 +r_0340 dihydroceramidase -0.0001328280584659 0.0024187135884035 -1820.9357392835584 1.064516572061449e-09 7.0964368946007884e-09 666.6347035686305 3.2490808280398004e-10 7.316037531595267e-09 2251.725309034278 7.509426145451157e-10 6.816703777039912e-09 907.7529554197876 8.933050516852115e-10 7.237428934239277e-09 810.1856046359454 6.310490681781407e-10 7.111829170619135e-09 1126.9851314654843 3.5641573372245146e-11 6.678582858912372e-09 18738.18192356549 6.184820495498717e-11 7.018636237912011e-09 11348.164822277608 1.8020518165723501e-09 8.797410083124626e-09 488.18851945434176 +r_0341 dihydroceramidase -1.3464358588934916e-05 0.0002342692073347 -1739.921035134244 -0.0001686979584536 0.003606997679358 -2138.139496423626 -0.0001822576054666 0.0031069367451357 -1704.695251087389 -0.0005124702202662 0.0065647781529055 -1281.0067577185737 -0.0004335081319213 0.008785705389768 -2026.65296054056 -3.521507588410814e-05 0.0007333545264615 -2082.501621961517 -0.0008784166055381 0.0159754702565727 -1818.6666959449656 -0.0008738509767827 0.0191451213800986 -2190.890882858073 -0.0010693482699639 0.0208449085320952 -1949.3096045124275 +r_0342 dihydroceramidase 1.2458043406329858e-10 3.556012885064048e-09 2854.3911504251614 1.5626047507354758e-10 3.055461729218982e-09 1955.364418149157 3.6402247834791557e-10 3.148762178164188e-09 864.991138034819 6.236742313422041e-11 3.888018145715928e-09 6234.052892242407 2.06028664591446e-11 2.995660639543091e-09 14540.01871770355 -6.696464124100868e-11 3.22714098106818e-09 -4819.171612453742 2.169057576051128e-10 3.356918352359368e-09 1547.6391172938786 2.3414636204775016e-10 2.934222686763399e-09 1253.1574956372856 1.3335469654452334e-10 3.500097184323553e-09 2624.652355723348 +r_0343 dihydroceramidase -1.2243354308332919e-10 3.906830580191095e-09 -3190.9805775465275 6.628675767797379e-10 3.1336186762270982e-09 472.7367555749916 5.134354413658908e-10 3.6122861282828682e-09 703.5521581200383 5.84458754403211e-10 2.886830151217517e-09 493.9322286591892 5.452795424672342e-10 3.0475281773523072e-09 558.8928136865563 -1.0750246790947604e-10 4.3423708059121825e-09 -4039.321971258126 3.7001723961909205e-10 2.8126092438745754e-09 760.129243375246 9.032149926204126e-10 4.425846682745904e-09 490.010320788145 5.479430199942691e-10 3.167078997461165e-09 577.9942223726638 +r_0344 dihydrofolate reductase 9.880636727978071e-05 0.0002851034061389 288.5476047628441 0.000163065566006 0.0004716821240635 289.259183049108 0.0003481621649388 0.0005740248624763 164.87284383042692 0.0005041894368397 0.0007419616649077 147.159303764561 0.000782001274961 0.0019852784669862 253.87151281629824 0.0008619977611988 0.0012155098134355 141.01078542768408 0.0009635590973896 0.0020748058748603 215.32730898199583 0.0013385764794971 0.0046918072842502 350.50722585628773 0.0014306568467008 0.0043014609831135 300.6633626388314 +r_0345 dihydrofolate reductase -7.606122577364835e-10 1.4027448842127395e-09 -184.42312360139803 -7.068016061030368e-10 2.9588538919150436e-09 -418.6258019741547 -7.633134859147992e-10 3.128098960955254e-09 -409.8052790468333 -2.5241754988789256e-10 6.477624606815007e-10 -256.6233849307208 -7.627736628179281e-10 9.86283591030824e-10 -129.30226082887802 -5.926768579839745e-10 8.189925577120966e-10 -138.1853444553156 -3.764203892729903e-10 8.959958473660816e-10 -238.030636198158 -2.2943385455223968e-10 7.685893785655733e-10 -334.99388312398065 -3.3794999391776376e-10 1.122491197275935e-09 -332.14712752712177 +r_0346 dihydrofolate synthase 1.436987612887239e-06 2.082713003827638e-09 0.1449360443436939 2.3423895575549425e-06 3.114112384134228e-09 0.132945964265006 5.444509710427241e-06 2.69462077219658e-09 0.0494924412943168 8.098203956458648e-06 2.181868448551232e-08 0.2694262160205415 1.1419221627312472e-05 4.784198087382981e-08 0.4189600870816049 1.353479041096314e-05 3.9179048395204727e-08 0.2894691916578908 1.5152735033287692e-05 7.134676317053633e-08 0.4708507276989994 1.7795814718847523e-05 1.0420894465519273e-07 0.5855811959248214 2.017776524370257e-05 1.0162029527803736e-07 0.5036251242428981 +r_0347 dihydroneopterin aldolase 1.4387585958703104e-06 1.076338428472802e-08 0.7481021705533031 2.3440709011700384e-06 1.1588955762907178e-08 0.4943944211381393 5.447877068414605e-06 1.6166419553629508e-08 0.2967471429808551 8.098340451280882e-06 2.170236760743649e-08 0.2679853698173916 1.1419215491986495e-05 4.783953822534133e-08 0.4189389214952027 1.3534791396601183e-05 3.917880482567012e-08 0.2894673709970039 1.5152735222525703e-05 7.13467172700775e-08 0.4708504189000487 1.7795814718847523e-05 1.0420894465519297e-07 0.5855811959248227 2.017821210077644e-05 1.0152161063331637e-07 0.5031249058453989 +r_0348 dihydroneopterin monophosphate dephosphorylase 1.43380759784012e-06 7.895899200150095e-08 5.506944733759561 2.3458527769333342e-06 1.5414835985259413e-07 6.571101194769257 5.448073555202645e-06 4.735694502679962e-07 8.692420274240982 8.037755359663406e-06 6.96556864883725e-07 8.6660620249693 1.1324512920301832e-05 1.0323713787825083e-06 9.11625414751165 1.342666012061384e-05 1.206555098353531e-06 8.98626380287319 1.507116648288732e-05 1.1129104338045136e-06 7.384368257547794 1.76144637795849e-05 1.7913246813252788e-06 10.169623689603412 1.993618772933048e-05 2.199786318220265e-06 11.034137258769384 +r_0349 dihydroorotase -0.0024701106957942 0.0004401585674912 -17.819386323079108 -0.0040302650511452 0.0007797818850133 -19.348153908431325 -0.0092811312718676 0.0008659586475509 -9.33031353813272 -0.0137847495071843 0.0012153660941694 -8.816744138412211 -0.0195994106820898 0.0032437220889671 -16.55010011056755 -0.0230521584841813 0.0017647724722386 -7.655562811828072 -0.0258180671812165 0.0031838440253061 -12.331844994277908 -0.0307712975186701 0.0074638682578432 -24.255942581929187 -0.0347037674799232 0.0067703518754673 -19.50898235871385 +r_0350 dihydropteroate synthase 1.438421544360158e-06 4.8966254669939016e-08 3.404165827599606 2.3432847825216403e-06 7.671263243971004e-08 3.2737221276689445 5.4449133481026925e-06 1.5698961371477926e-07 2.883234381856289 8.0900841462443e-06 2.570324156525747e-07 3.177129075621521 1.1409873999306786e-05 3.263907473133794e-07 2.8605990507275494 1.3515672114924878e-05 5.075995029426791e-07 3.755636409543813 1.5134313390979692e-05 5.296575012435404e-07 3.499712788815548 1.777043790883871e-05 6.733860006709469e-07 3.789360758161263 2.016176964895796e-05 5.794027666182329e-07 2.873769399742045 +r_0351 dihydropteroate synthase 3.370515101503024e-10 4.8449982631679216e-08 14374.652292782715 7.861186484005374e-10 7.72279260524707e-08 9823.952937587876 2.963720311913668e-09 1.566510730528506e-07 5285.622682516264 8.256305050977742e-09 2.5739099070660414e-07 3117.5082451213807 9.341492679704777e-09 3.275050967611863e-07 3505.9182508671265 1.9119281676306145e-08 5.106867850585379e-07 2671.0563383320728 1.8421831546011652e-08 5.315487249059342e-07 2885.428213683862 2.537681000881e-08 6.778734258068012e-07 2671.2318276862443 1.6442451818481155e-08 5.802016834648602e-07 3528.6810621072896 +r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.0107042011860401 0.0054521806847415 50.93496086239531 0.017038841981713 0.001809182664447 10.6179907436714 0.0472308611598065 0.0052947606338007 11.210383431049031 0.0787232911788867 0.0052837183930985 6.711760031846299 0.0856945528232948 0.0134012568786366 15.63839991821946 0.1198004584666212 0.0147937029547767 12.348619649814289 0.1389759458806026 0.0208945916223406 15.034682073897674 0.1755822184838486 0.0323130094026046 18.40334954281096 0.1851432176234126 0.0301630519585001 16.29174017049483 +r_0353 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate) 0.0042211911330579 0.0030707206928651 72.7453601618999 0.0066940572265752 0.0011505808435696 17.188093926085486 0.0184809547492617 0.0028310934783083 15.318978465771313 0.0309042586543443 0.0033751935751223 10.921451353591523 0.0336361144822849 0.0079457980821438 23.622817927821654 0.0470225431466737 0.0089587810545294 19.052098110867927 0.0544810842792153 0.0121277819668934 22.260537078775084 0.0687090247361664 0.017115599801579 24.910264506446893 0.0726517220583299 0.0169596819908387 23.34381279664963 +r_0354 dihydroxyacetone kinase 4.0212171295213664e-10 5.122437856178866e-10 127.38525901953908 5.41464019532448e-10 5.842357713311767e-10 107.89927866964496 7.00304846640729e-10 5.376591490397465e-10 76.77501471235385 5.810394687331151e-10 5.230025806240193e-10 90.01154117195549 4.730168397788256e-10 5.736996133693388e-10 121.28524084630696 3.4006803730709304e-10 5.30195669697595e-10 155.90870400407854 6.651758515332106e-10 5.120580613459302e-10 76.98085553852441 7.438458603646032e-10 4.6398220240966647e-10 62.37612214205792 5.324000000000234e-10 5.17787466797098e-10 97.25534688149418 +r_0355 dimethylallyltranstransferase 0.0017387017218494 0.0004704778943728 27.05914927560996 0.002770078975102 0.0003279418182545 11.838717278538402 0.0064071542065942 0.0004960230598835 7.741706284718634 0.0095232241388507 0.000753042965135 7.9074371678695075 0.0135128835626083 0.0015599666154681 11.544291107375356 0.0159587963525963 0.0015250087834939 9.555913552627542 0.0179375591865093 0.0023267857602088 12.971585130483074 0.0211470142755956 0.0032761696180095 15.492350718230416 0.023903403965598 0.0031857967281831 13.327795207611985 +r_0356 diphosphoglyceromutase -3.699999999999991e-11 1.8983731888522776e-10 -513.0738348249413 -2.359999999999996e-11 1.5181452344852974e-10 -643.2818790191949 -2.259999999999997e-11 1.4863935794986667e-10 -657.6962741144553 -7.280000000000041e-11 2.5983391374597743e-10 -356.9147166840329 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0357 diphosphoinositol-1,3,4,6-tetrakisphosphate diphosphohydrolase 0.0001328791992942 0.002554062177309 1922.09329291094 0.0002150117985067 0.0042445062008116 1974.0805994321213 0.0002043654394801 0.0039281308231668 1922.1111128963048 0.000236683168803 0.0050264502717071 2123.704147247783 0.0004685181215895 0.0105754693272717 2257.2167094397582 0.0004651135313084 0.0092674252367096 1992.5081970068447 0.0009048542120762 0.0173978802039903 1922.727437392344 0.0011443907589276 0.0246841512793217 2156.968770217355 0.0010260909383219 0.0231659814358222 2257.692819479374 +r_0358 diphosphoinositol-1,3,4,6-tetrakisphosphate synthase 4.4293642454316727e-05 0.0018078960067606 4081.615118073162 5.375327295066204e-05 0.0026873670556318 4999.448234712047 6.812493392329628e-05 0.002780610959424 4081.634725040393 6.709150438501498e-05 0.0033542139301186 4999.461497941592 0.0002009220211388 0.0082009415236709 4081.6539059220177 0.0001641629307554 0.0067005614001922 4081.653129215497 0.0003020086557062 0.0123269680826186 4081.66052519037 0.0004568721580297 0.0186481803702838 4081.706456069403 0.0004403334563833 0.0179729107442514 4081.659134390816 +r_0359 diphthine synthase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0360 dolichol kinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0361 dolichyl-phosphate D-mannosyltransferase 0.0210693032639376 0.0001556719111275 0.7388564736925628 0.0334436119823008 0.0002063273361276 0.616940945962407 0.0683715719418947 0.0001926406858326 0.2817555313725706 0.0903990446793599 0.0002447409761445 0.2707340293391953 0.1601433339189001 0.0006742763447699 0.4210455273220242 0.1671155370820592 0.0004867447182323 0.2912623965019507 0.1813989425947403 0.0008570502740961 0.4724670727606674 0.1986324404306186 0.0011660469787323 0.5870375333477377 0.2415558085197562 0.0012161449605629 0.5034633478761753 +r_0362 dolichyl-phosphate-mannose--protein mannosyltransferase 0.0210693030818091 0.0001556719995988 0.7388568999858718 0.0334436118568529 0.0002063273643775 0.6169410327470856 0.0683715718389072 0.0001926407183005 0.2817555792844486 0.0903990444922377 0.0002447410512149 0.2707341129428822 0.1601433335723594 0.00067427633542 0.4210455223947361 0.1671155367230353 0.0004867447520389 0.2912624173572014 0.1813989423912062 0.0008570503485677 0.472467114344791 0.1986324405658122 0.0011660469974193 0.5870375423560323 0.2415558084763655 0.0012161450588206 0.5034633886436598 +r_0363 dTMP kinase 8.243244055250765e-05 0.001880662801042 2281.4595666909704 0.0001005957416262 0.0027851796587226 2768.6854470144845 0.0001348175862846 0.0029041309302761 2154.1187691521586 0.0001687209013197 0.0040344001307972 2391.167957995024 0.000239182528786 0.006577221229268 2749.8752783706286 0.0001527473180744 0.0046766314381345 3061.6782651826043 0.0003020045572559 0.0095464008118347 3161.012170999563 0.0006212921912522 0.0160007124408986 2575.392491035248 0.000474708340416 0.0139884348347687 2946.743009088361 +r_0364 dUTP diphosphatase 0.0001458922317201 0.0025057377443038 1717.5265021040066 0.0003040420699815 0.0048668411440272 1600.7130672156904 0.0002351882417705 0.0038709127194146 1645.878505776016 0.0003189110556535 0.0055288261152007 1733.6577133927178 0.0009208597705316 0.0133523429400033 1449.9865633499448 0.0007326313140841 0.0106728760657716 1456.7867712717368 0.0008917776064689 0.0160303928129837 1797.577411307428 0.0013179443523855 0.0235134036806049 1784.0968503749657 0.0016070441227639 0.0257959239857816 1605.1783283594862 +r_0365 endopolygalacturonase 1.2e-12 3.4623687844479196e-11 2885.3073203732665 4.799999999999999e-12 6.912246800510246e-11 1440.0514167729682 5.520000000000002e-11 2.2839306617875598e-10 413.7555546716592 4.5960000000001804e-10 4.984150113155646e-10 108.44538975534051 9.23399999999985e-10 2.659823101596455e-10 28.80466863327375 5.818000000000274e-10 4.933127116609755e-10 84.79077202835205 5.599999999999999e-12 7.463078420323923e-11 1332.6925750578437 3.0820000000000675e-10 4.617958543363034e-10 149.8364225620679 1.759999999999999e-11 1.31505508400778e-10 747.1903886407845 +r_0366 enolase 0.5174133436086963 0.0478226771499337 9.242644732815506 0.7480235620969493 0.0811106485364768 10.843328024199897 1.7847048572697033 0.1317954077848877 7.384717268406635 2.494025929324456 0.1803404974255787 7.230899057830835 3.5084571397356528 0.368629251477503 10.50687629335776 4.284283298521858 0.2809299758818203 6.55722220747506 4.870796731727067 0.4395132043287982 9.02343555964729 8.457052228625821 0.7337789112446935 8.676532808452627 12.143681831980366 0.6298801505972949 5.1868960280110965 +r_0368 ethanolamine kinase -4.756000000000192e-10 5.167765973903231e-10 -108.65782115018968 -3.722000000000116e-10 5.088407843213442e-10 -136.71165618520374 -3.0920000000000675e-10 4.968347098842593e-10 -160.68392945803632 -2.5440000000000276e-10 4.566424689720627e-10 -179.49782585379631 -3.6500000000001104e-10 5.12471975336316e-10 -140.403280914055 -4.2420000000001555e-10 5.19141851185524e-10 -122.38138877546088 -3.030000000000064e-10 4.712063317501224e-10 -155.51364084162137 -1.875999999999981e-10 4.015451253564545e-10 -214.04324379342145 -1.7559999999999844e-10 3.9597474565916485e-10 -225.49814673073368 +r_0369 ethyl acetate-hydrolyzing esterase 0.0001329120815797 0.0026915500908972 2025.060520387919 0.0002184794246924 0.0046730836516307 2138.91246656707 0.0001969866484079 0.0048119046646702 2442.756757150277 0.000465681646892 0.0092944945342106 1995.890238802061 0.0007604220189866 0.0139909624997412 1839.8944468211723 0.0003681110025772 0.0102612601653213 2787.545086530657 0.0006268108110104 0.0149564320421671 2386.1158390130254 0.0008423627266011 0.0205036915489803 2434.0691843892323 0.0014038509323061 0.027095782233257 1930.1039454913 +r_0370 exo-1,3-beta-glucan glucohydrase 9.20999999999986e-10 2.6976574043220496e-10 29.29052556267199 8.229999999943633e-10 3.8170687710075855e-10 46.37993646456534 8.592000000165552e-10 3.4842451109621765e-10 40.552201011348245 7.37000000000039e-10 4.4076054039670865e-10 59.80468662098851 1.1100000000000043e-10 3.1606799869009783e-10 284.7459447658528 9.185999999999867e-10 2.7347577186937803e-10 29.770930967709774 9.201999999999859e-10 2.710104229173804e-10 29.45125221879857 7.108000000000371e-10 4.538772531336729e-10 63.85442503287132 7.728000000000374e-10 4.1906477191073774e-10 54.22680795946137 +r_0373 farnesyltranstransferase 4.3094446046207056e-10 5.88810522895971e-10 136.632577261727 6.07706453430112e-10 5.831596948639239e-10 95.96075400752493 6.381850832511995e-10 1.3304256554819211e-09 208.4701899806462 5.275968332173418e-10 9.98454191424852e-10 189.24567559213187 6.024764476802216e-10 5.244591808068477e-10 87.05056983160557 4.670961656243421e-10 7.885824568777831e-10 168.8265746784128 6.196723599909081e-10 5.149481902451002e-10 83.10007408635354 5.72073674753057e-10 5.192929043357421e-10 90.773780939999 5.784982316154701e-10 8.157884115018643e-10 141.0183068708362 +r_0399 fatty-acid--CoA ligase (decanoate) 1.976748381458809e-05 0.0011061375210047 5595.74264170362 8.939928050043853e-05 0.0026578236837418 2972.9810674805185 6.594027536881573e-05 0.0020960174434342 3178.660434326127 0.0001237525281911 0.0034245802980838 2767.2810795388564 9.311377232654064e-05 0.0044102668459439 4736.428066170094 3.526545595878027e-05 0.0036717494914145 10411.74540804546 0.0002151781470503 0.0085693460016438 3982.442510594742 0.0005843195537589 0.0163818098353749 2803.5703631670003 0.0002925647358901 0.0109929793231943 3757.451932730771 +r_0400 fatty-acid--CoA ligase (dodecanoate) -0.000128386162386 0.0020088244864276 -1564.673675958452 -0.0001336378007241 0.001985477410577 -1485.715418705454 -0.0001786676097385 0.0031566876231398 -1766.7934483253457 -0.0002034986645432 0.0045971312611504 -2259.04738562765 -0.000493245695438 0.0086578210205351 -1755.2755352169406 -0.0003702248229446 0.0066773683951325 -1803.5982412044727 -0.0009195105514402 0.013398981692582 -1457.186290205707 -0.0021653027415977 0.022509618138881 -1039.559859526708 -0.0014206005187487 0.0220373900935767 -1551.2728457249036 +r_0402 fatty-acid--CoA ligase (hexadecanoate) 7.999247346408172e-05 0.0020277533115626 2534.9301299866943 -2.6583908337974577e-06 0.0046066586009046 -173287.48438107385 0.0001424780664046 0.0029977038392052 2103.975660851529 0.0001436351490617 0.0053766673107497 3743.2810463683177 0.0003680203242743 0.0095773579119108 2602.3991829245515 -4.9192124288490686e-05 0.0080122395945639 -16287.64707857618 0.0006955884943315 0.0154324773498157 2218.6217103326985 5.10318709133541e-05 0.0185946035432289 36437.2365943634 0.0008010322602263 0.0196556370626009 2453.788447552403 +r_0410 fatty-acid--CoA ligase (octanoate) 1.95419238070471e-05 0.0013970754530635 7149.119333685006 6.823979969216898e-05 0.0022181425779053 3250.511560572325 6.358439024518267e-05 0.0021152092705382 3326.617212781322 0.0001132041288713 0.0034931398832763 3085.7000695130514 0.0001403399136065 0.0052540741286185 3743.820267233056 2.392149208715724e-05 0.0041986246148682 17551.683647369147 0.000470869331637 0.0115794633876825 2459.167036304073 0.0004927495664224 0.0147278685982032 2988.9155875131605 0.0004009632487729 0.0136750018422263 3410.5374704728683 +r_0412 fatty-acid--CoA ligase (tetradecanoate) 4.064743538876436e-05 0.0022893005401416 5632.090975103663 -9.780689474262142e-05 0.0032272161317073 -3299.5793805741487 7.534040833462826e-05 0.0041985324169696 5572.74974980448 1.5061786214195573e-05 0.0051378936768632 34112.11395379386 8.624978150464518e-05 0.0094829432852849 10994.744705265412 0.0001928574614033 0.005571173530995 2888.7518742883667 0.0004884727637962 0.0155858486728422 3190.7303391316327 0.0018667822018948 0.0238355557854765 1276.8257465323074 0.000646814186119 0.0225546961470812 3487.044135876188 +r_0436 ferrochelatase 1.3958300027697393e-05 0.0001439643071457 1031.3885420150002 8.005870425168122e-06 0.0001060046016239 1324.0859018993854 1.4420959896678798e-05 0.0001678546895839 1163.9633615696166 1.3929740261216104e-05 0.0002030935407581 1457.9851235533924 4.5321988490550056e-05 0.0005130161875274 1131.9366263782815 3.858686306299114e-05 0.0004661301890677 1208.0022890349371 4.060589021861432e-05 0.0005824694980955 1434.4458278333525 9.34688550121009e-05 0.0011187945451572 1196.970418662359 9.266253276387528e-05 0.0010814234121756 1167.055745099601 +r_0437 ferrocytochrome-c:hydrogen-peroxide oxidoreductase -8.46600000000021e-10 9.243588739583619e-10 -109.18484218737764 4.0260000000001875e-10 9.88488068583668e-10 245.5260975120769 -6.432000000000283e-10 8.75241092153435e-10 -136.07604044673448 -2.4330001812711473e-10 1.096674785848935e-09 -450.7499811512408 -7.63200000000033e-10 9.366435929658812e-10 -122.72583765275688 -2.2740000000000086e-10 1.0624099881856422e-09 -467.19876349412414 -9.166000000000014e-10 7.534971742470805e-10 -82.20567033025088 -8.61200000000011e-10 7.175217958400205e-10 -83.31651136089309 -1.2400000000000018e-11 1.061918911383941e-09 -8563.862188580157 +r_0438 ferrocytochrome-c:oxygen oxidoreductase 3.84687277460682 0.0145015064091235 0.3769687031203074 6.988095881871845 0.1262927592329409 1.807255672615526 11.036143562905734 0.0296009012328816 0.2682177978580771 18.46797462408609 0.1554934738193384 0.8419627868480094 25.693048227600684 0.08352964542427 0.3251060157764329 26.915484867499995 0.0517442906509028 0.1922472914964397 36.43385020825973 0.1860837352714662 0.5107440860842101 44.07634969606108 0.1730261406772625 0.3925600506176334 43.7601842548103 0.1855453509502933 0.4240049581827285 +r_0439 ubiquinol:ferricytochrome c reductase 1.923187733306828 0.0081322067623248 0.4228503864436532 3.4934355596771747 0.0631769062688684 1.8084463042079568 5.517784246736572 0.0155817988885321 0.2823923189412092 9.233088530919328 0.0782224641062164 0.8471971631623458 12.845536198320833 0.0444707573765147 0.3461961936811011 13.456705142974643 0.0297744643592959 0.2212611782969797 18.215072971504 0.0960128457065632 0.5271065663956852 22.035409567118805 0.0953578723566806 0.4327483547161906 21.87803701665273 0.0984361949556272 0.4499315678125116 +r_0440 FMN adenylyltransferase 2.248478153732176e-07 2.7253661630731892e-08 12.120936814749312 3.674931838226294e-07 3.40835949744863e-08 9.274619632383915 8.508393698167751e-07 9.013504031584725e-08 10.593661214249815 1.2670602818591749e-06 1.19709627334146e-07 9.447824152335864 1.7827286615404405e-06 1.9719210293434403e-07 11.061251618849946 2.113066830254492e-06 2.2015117402755363e-07 10.418561820926367 2.37332776469988e-06 2.3363238560586025e-07 9.844084288770976 2.779852298403749e-06 3.224534540754948e-07 11.599661401458429 3.1468828968640457e-06 3.716616122945422e-07 11.810468469129026 +r_0441 FMN reductase 0.0023824949268174 0.0622395105482292 2612.3669707606928 0.0049293545442616 0.1210801666532099 2456.308743183466 0.0089346695156631 0.2012687423846872 2252.671372252194 0.0132949765116795 0.3236778832370725 2434.587853184426 0.01910590883081 0.4532295215641846 2372.195563046499 0.0193132679452099 0.476521443818862 2467.3268406502284 0.0316276011508073 0.6683619090028949 2113.223528449085 0.0582134270929131 0.9526864737877024 1636.5407799598208 0.0419591161417463 0.8980649545450983 2140.3333461821617 +r_0442 FMN reductase 0.0001771722936052 0.0062621066654619 3534.4728783690443 8.062903599374006e-05 0.0057013338111716 7071.067811866493 0.0002725026241572 0.0096313553721513 3534.408302282102 0.0004025458709073 0.0142278746636661 3534.472886678708 0.0008330398652954 0.0284743159853685 3418.1216495888984 0.0006564292152216 0.0232013118539652 3534.472768115552 0.000960689114685 0.0371796532270001 3870.102477344121 0.001607964970148 0.0584831444142605 3637.090701601222 0.0015147044176025 0.0556218005456206 3672.1224219875344 +r_0443 formaldehyde dehydrogenase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0445 formate dehydrogenase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0446 formate-tetrahydrofolate ligase 0.0008918369247141 0.0019400398958613 217.5330312190494 -0.0012141990393059 0.0030872236879996 -254.2600997085628 -0.0054186240889413 0.0026588134939624 -49.06805584444861 -0.0030349558816292 0.003507239537194 -115.56146692027993 -0.0007695728972705 0.0047299167171838 -614.6158127396675 0.009743714717989 0.0042463279253317 43.580174997242985 0.0020778461820307 0.0060419950214615 290.7816311771681 0.0057893395861327 0.0098315245414248 169.82117554434487 0.0062556515934891 0.0095298215256262 152.33939076058755 +r_0447 formate-tetrahydrofolate ligase -6.612003873198163e-10 6.38197682896409e-10 -96.5210691244981 -2.2480393659937348e-10 8.637246568454387e-10 -384.2124252408868 -2.8891337527430837e-10 2.389951334584833e-09 -827.220730890599 -3.4989483335762157e-10 8.03728989917183e-10 -229.70587539247984 -4.037252663412423e-10 8.690696583760181e-10 -215.2626379448472 -3.058000000000061e-10 7.32662076774644e-10 -239.58864511923787 8.603012622367846e-11 9.307779192745571e-10 1081.9209039104894 2.0843324136044558e-10 9.242586925528735e-10 443.43152105692417 -2.1031198125100358e-10 8.945568974338024e-10 -425.347567985756 +r_0448 fructose-2,6-bisphosphate 2-phosphatase 7.382205029116925e-05 0.0023335172634738 3161.0030529766414 0.0001611484171615 0.0046496147618256 2885.299678225137 0.0001111116416385 0.0035155281442366 3163.9602227045325 0.0001341823265825 0.0047426274986951 3534.4650964715183 0.0004662136405517 0.0124537697165244 2671.2581171556985 0.0002180946909973 0.0077085711907851 3534.506573972299 0.0004024794972691 0.0142255274754057 3534.4725810699933 0.0006086989292063 0.0215145183895911 3534.5089924246176 0.0008744987410871 0.0252350722026565 2885.6613528436965 +r_0449 fructose-bisphosphatase 0.0002133068134156 0.0030197644439906 1415.690570608319 0.0016434032738639 0.0131371091912114 799.3843872736027 0.0001128178855294 0.00356640766836 3161.207685841063 0.000100368388787 0.0040967317859571 4081.695278229504 0.0004562818165463 0.0105080421661933 2302.9719320683203 0.0002186797210296 0.0077291803055834 3534.4751077930523 0.0010603563593827 0.0178595157919966 1684.2937408696064 0.0 0.0 0.0007335891187109 0.0231888495555241 3161.013292600384 +r_0450 fructose-bisphosphate aldolase 0.2455457374838328 0.041809931631399 17.027349796349814 0.3434986302512774 0.0785401909997344 22.86477560107894 0.8358909394486779 0.1108389622060707 13.259978900976716 1.1446569135688391 0.18049750154642 15.768698848256683 1.5896736149261304 0.3181726033723263 20.01496410237087 2.0244373041352084 0.2666919130244016 13.17363162986794 2.2505710380783017 0.3825369986792887 16.997330553312644 4.003053278075916 0.6003963958762158 14.99846127865675 5.762579489110149 0.4585363599603209 7.957137265123046 +r_0451 fumarase 0.2571003798455956 0.0417257161023163 16.229348290879685 0.4211696918668864 0.0807120879988374 19.16379301679358 0.5628460689212539 0.1065779771930842 18.93554616048944 0.9120038095865364 0.2087882594275834 22.893353869019386 1.220183058145886 0.3154952056737242 25.85638307035101 1.6198894033092894 0.2608474307287636 16.102792585461426 1.997038931620395 0.3739625575638821 18.7258521425243 2.451697320167922 0.5540459332043363 22.5984638742595 1.6869131370411925 0.5504492051023463 32.63056010505804 +r_0452 fumarase, cytoplasmic 0.0090595202505709 0.0096700362999765 106.73894458558284 0.087864871878422 0.0385648789679486 43.89112297495925 0.1858583763754603 0.0730895924859467 39.32542288989728 0.3107145153725835 0.1844622538029771 59.36711826345963 0.6925447095795877 0.2530908324301855 36.54505318275053 0.0891770729175101 0.0420846645934029 47.19224708387969 0.6250780603346665 0.2568991250901377 41.09872692581691 0.5172279404048512 0.2496271668656007 48.26250621151854 1.5667503419560618 0.6964450062599232 44.4515624225378 +r_0453 dihydoorotic acid dehydrogenase 0.0024701106957942 0.0004401585674912 17.819386323079108 0.0040302650511452 0.0007797818850133 19.348153908431325 0.0092811312718676 0.0008659586475509 9.33031353813272 0.0137847495071843 0.0012153660941694 8.816744138412211 0.0195994106820898 0.0032437220889671 16.55010011056755 0.0230521584841813 0.0017647724722386 7.655562811828072 0.0258180671812165 0.0031838440253061 12.331844994277908 0.0307712975186701 0.0074638682578432 24.255942581929187 0.0347037674799232 0.0067703518754673 19.50898235871385 +r_0454 fumarate reductase 0.0045209839288432 0.0902638336242627 1996.5528532050544 0.0083466374459156 0.1627458475679437 1949.8372682712 0.0192083193855628 0.3213761912978695 1673.109369159174 0.0319620824313094 0.5349958837700067 1673.845516542233 0.0400907733102539 0.7031665585905517 1753.936131760032 0.035777243552553 0.6838230306678101 1911.3351470561056 0.0944832931673657 1.1091340695120335 1173.8943810387052 0.054369172276978 1.0109630902708864 1859.441753353612 0.073295682947909 1.2366336027725136 1687.1847741037964 +r_0455 soluble fumarate reductase 2.313042252072005e-09 2.7163752429587292e-08 1174.3733779724175 2.587823360944779e-09 3.3966967682476245e-08 1312.5690182376036 8.567846836785495e-09 9.006079417987538e-08 1051.1485078515318 1.0471271573265376e-08 1.1966933397983437e-07 1142.8347850834746 1.8610790480764912e-08 1.9688856414809282e-07 1057.926928743763 2.194228710895445e-08 2.19920349603938e-07 1002.2672135859092 1.690698035910032e-08 2.3328300741598414e-07 1379.8029125314365 2.7248295710112237e-08 3.2172088576295617e-07 1180.7009479993312 3.6019279065996995e-08 3.709694122391304e-07 1029.9190374116451 +r_0457 g-glutamyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0458 galactokinase 2.067999999999992e-10 4.4863572617766215e-10 216.9418405114429 8.598000000000058e-10 5.282042786195167e-10 61.43338899971076 4.989646707716947e-10 5.213113365851143e-10 104.4786068277857 4.954000000000202e-10 5.499448407482071e-10 111.01026256523711 2.242000000000004e-10 4.690185024827151e-10 209.19647746775848 1.4519999999999938e-10 4.66648167362123e-10 321.3830353733644 2.2742579678083408e-10 5.83252155719288e-10 256.45822240709 3.2860000000000805e-10 5.02665469785733e-10 152.97184107903857 1.6699999999999875e-10 4.0092785963277287e-10 240.0765626543568 +r_0459 galactose-1-phosphate uridylyltransferase 0.0002879011678446 0.0066011108607819 2292.8392094417136 0.0001369405979843 0.0056173488878736 4102.033268845362 0.0004688467564063 0.0119277179318126 2544.054697794405 0.0005943213612192 0.0149685054535967 2518.5878264394 0.000974212571549 0.0273708675253124 2809.5374997873937 0.0009852327623812 0.0268587644742918 2726.1339147285685 0.0021245696815736 0.0466979690929958 2197.996587168053 0.0014178971142659 0.0449835157248385 3172.5514688085605 0.0022363255901102 0.0570859031798081 2552.665114250777 +r_0460 gamma-glutamylcysteine synthetase 6.643968385163965e-05 0.0015055469846774 2266.035744600102 0.0001597708076996 0.0031760484579648 1987.8778255511684 6.03942404550051e-05 0.0017691610238824 2929.353876385727 0.0001612263977387 0.0034947161852531 2167.583121789103 0.000178774995452 0.0052330619018165 2927.1777569256287 0.0001278951590164 0.004077057629814 3187.812315310656 0.0002672900079628 0.0078216547187569 2926.280252063776 0.0006114442105296 0.0152684200214992 2497.107627901856 0.0003917238987938 0.0114686018552466 2927.725852458861 +r_0461 geranylgeranyltranstransferase 4.3094446046207056e-10 5.88810522895971e-10 136.632577261727 6.07706453430112e-10 5.831596948639239e-10 95.96075400752493 6.381850832511995e-10 1.3304256554819211e-09 208.4701899806462 5.275968332173418e-10 9.98454191424852e-10 189.24567559213187 6.024764476802216e-10 5.244591808068477e-10 87.05056983160557 4.670961656243421e-10 7.885824568777831e-10 168.8265746784128 6.196723599909081e-10 5.149481902451002e-10 83.10007408635354 5.72073674753057e-10 5.192929043357421e-10 90.773780939999 5.784982316154701e-10 8.157884115018643e-10 141.0183068708362 +r_0462 geranyltranstransferase 0.0017387017218494 0.0004704778943728 27.05914927560997 0.002770078975102 0.0003279418182545 11.838717278538402 0.0064071542065942 0.0004960230598835 7.741706284718634 0.0095232241388507 0.000753042965135 7.907437167869514 0.0135128835626083 0.0015599666154681 11.544291107375356 0.0159587963525961 0.001525008783494 9.555913552627764 0.0179375591865093 0.0023267857602088 12.971585130483074 0.0211470142755956 0.0032761696180095 15.49235071823042 0.023903403965598 0.0031857967281831 13.327795207611985 +r_0463 glucan 1,4-alpha-glucosidase 1.7720597633853158e-05 0.0008857728532493 4998.549549803104 4.838019608520915e-05 0.0019746049261272 4081.432251017529 1.489528609887425e-09 1.8372858698987363e-09 123.34679963197172 4.025631183632973e-05 0.0020125254527347 4999.279270582693 0.0001205552811887 0.0049205661801153 4081.5849223665823 0.0001313322920635 0.0046418187104993 3534.40775118267 0.0001208054796493 0.0060395587406063 4999.407939223542 0.0003667009457368 0.0129608714078374 3534.452680997053 0.000176135813114 0.008805772662336 4999.422040668577 +r_0464 glucan 1,4-alpha-glucosidase, vacuole 2.6574604824376407e-05 0.0010847380111855 4081.859423138324 4.8314423235642576e-05 0.0019720378062524 4081.67514829736 5.449929645899987e-05 0.001926270013999 3534.486019371215 2.0126835135177125e-05 0.0014232140739031 7071.226371878588 0.0003113220324675 0.0078050481220213 2507.0657737131824 0.0001969944907889 0.0056839077012955 2885.3130250146405 0.0001812047481371 0.0073961812136836 4081.670756267487 0.0006263443910679 0.0167599866024175 2675.8420513418896 0.000598767558827 0.0160337695734572 2677.795304219005 +r_0465 glucosamine-6-phosphate deaminase 4.41132518911288e-05 0.001800516275588 4081.576846866159 0.0001075068569883 0.0037997500464473 3534.42575933477 2.2709702106762875e-05 0.001605707636062 7070.579915638228 1.2403722590235611e-09 1.026135878824701e-09 82.728057755217 0.0002009228749309 0.0082009418904374 4081.636744077879 0.0001563925159109 0.006399115344486 4091.7017717969975 1.4917151856880191e-09 1.1401767437831582e-08 764.3394360547976 0.0007639570946151 0.0241487405607486 3161.0074349678416 0.0008806666789058 0.0254099040745658 2885.303223477861 +r_0466 glucose 6-phosphate dehydrogenase 0.1518164689461646 0.1222602222465491 80.53159390099083 0.3113446561747209 0.2398666904557582 77.04217358436031 0.6569314824571103 0.313077605260402 47.65757367715167 1.101905159452342 0.5437055418259025 49.34231745462827 1.585118138396738 0.9339281380816592 58.918519412457 1.4342438461206886 0.7857949735030078 54.78810145348776 1.980301841238367 1.1104391932515116 56.07423929662696 2.41341223802261 1.6243106426608889 67.30348910436209 3.0034807398142847 1.2410592511387946 41.320699503321386 +r_0467 glucose-6-phosphate isomerase 0.1724051068707802 0.1221769798259404 70.86621854972869 0.1808185488055756 0.2388064458170432 132.06966176562935 0.4948977723204432 0.3136774143405617 63.3822643552854 0.5450692864590794 0.5425476499266997 99.53737321198908 0.7497621810725983 0.9273183099240424 123.68165977609526 1.306885600133761 0.7876413882756653 60.26857960597695 1.1927079077163587 1.108101816114067 92.90638629500792 2.691350727864572 1.649876757857201 61.3029264738855 4.110668005737161 1.2290295610084232 29.89853618178593 +r_0468 glutamate 5-kinase 0.0025526198050993 0.0014977873896534 58.676477658809 0.0043319255482589 0.0032874286757719 75.88839279782097 0.0116128485719212 0.0036210428848362 31.18134936841926 0.0197229267612999 0.0059104598861518 29.96745846944594 0.0211741671918101 0.0077917522509977 36.79838824551985 0.0295889612452953 0.0083536839611205 28.2324340211464 0.0344283097613279 0.0115421625138316 33.5252081610947 0.0432109657581973 0.0182398801894941 42.21123011126858 0.0455727351679797 0.0179691381703215 39.42958021739928 +r_0469 glutamate decarboxylase 0.0002875022910065 0.0054820925726818 1906.7996131399468 0.0011233447828206 0.0125745238322796 1119.3824037447669 0.0008272915854357 0.01052257487099 1271.930605391946 0.0008772117283012 0.0123420446584464 1406.9630238924094 0.0011750274268619 0.0240228886990899 2044.4534442269144 0.0017979627620052 0.0232385359589551 1292.4926172017713 0.0021183090082912 0.0388316363612151 1833.1431443299728 0.0029415858578364 0.0556225022942368 1890.9018802241387 0.0034973170160316 0.0567931074352687 1623.905044207621 +r_0470 glutamate dehydrogenase (NAD) 0.0002566929146036 0.006338223464914 2469.1852031442554 0.000161258163833 0.0080621016992088 4999.499874968444 0.0002021859870547 0.0080787178584402 3995.6863361910414 0.0005413771295823 0.0159360570339262 2943.614748967964 0.0011173009962403 0.0322835823767888 2889.425721933708 0.000492486637477 0.0201016604393301 4081.6661630272174 0.002446647770638 0.0584948222980311 2390.8150163673663 0.0049726818469029 0.1059392837399588 2130.425532973507 0.0036838499317854 0.0805646748799317 2186.969512107238 +r_0471 glutamate dehydrogenase (NADP) 0.0886308726552194 0.0107363056655469 12.113505535832877 0.1503098099974743 0.013098582926678 8.714389916997508 0.550935732420853 0.0787821713639691 14.299702620084991 0.663623085183061 0.052434401317905 7.901232264010365 1.3356800363910126 0.3049522397362748 22.831234384564976 0.9966203982181424 0.0409653640216578 4.110428011999337 1.674108496246279 0.2729575957172455 16.304653869762728 1.8400214710548044 0.2616641860272036 14.220713733150236 2.970893613769144 0.7014527259045658 23.61083287040492 +r_0472 glutamate synthase (NADH2) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0473 glutamate-5-semialdehyde dehydrogenase 0.0025526198050993 0.0014977873896534 58.676477658809 0.0043319255482589 0.0032874286757719 75.88839279782096 0.0116128485719212 0.0036210428848362 31.18134936841926 0.0197229267612999 0.0059104598861518 29.96745846944594 0.0211741671918101 0.0077917522509977 36.79838824551985 0.0295889612452953 0.0083536839611205 28.2324340211464 0.0344283097613279 0.0115421625138316 33.5252081610947 0.0432109657581973 0.0182398801894941 42.21123011126858 0.0455727351679797 0.0179691381703215 39.42958021739928 +r_0475 glutaminase 7.270448491675599e-05 0.0022981893496551 3161.000799725741 0.0001343820705517 0.0042478249438905 3161.005725279013 0.0001528536567003 0.0040838072630546 2671.710544066278 0.0002134468106677 0.0057752882803494 2705.727137492624 0.0003929004331268 0.0113369118148684 2885.441414417358 0.000263090401408 0.0083163145894006 3161.010262971309 0.000692920079703 0.0185090166484014 2671.1618252329963 0.0004528477579354 0.0184844160999705 4081.816852586506 0.0004340659448404 0.017718041270553 4081.877761008112 +r_0476 glutamine synthetase 0.018935450118356 0.0032335848604696 17.076884046896986 0.031783121908455 0.0067311961488172 21.17852414940573 0.0793972788511042 0.0054019850086717 6.803740741294432 0.1263211880025036 0.0077809017529295 6.159617302502969 0.154840828734866 0.0169290473555931 10.933193456734063 0.1990479241647595 0.0123767786139156 6.21798929370947 0.22781969232637 0.0223732693346825 9.820603788118138 0.2798676973033905 0.037499910941709 13.399156566846388 0.3047376416899132 0.0374645256055373 12.294026231147225 +r_0477 glutamine-fructose-6-phosphate transaminase 0.0007618759537685 0.0018389530263351 241.37171113472468 0.0012570429883699 0.0038563728892186 306.78130540462433 0.0023515179117963 0.0018554440279766 78.90409929130584 0.0030737149618071 0.0011856352691613 38.57336428047604 0.005638721290486 0.0084707227040906 150.2241779245761 0.0057921961280078 0.0064558751566912 111.45815877114636 0.0061140695657116 0.0009565050382691 15.64432703928236 0.0075232994066898 0.0244686285550315 325.2380004080853 0.0090804289308618 0.0256902995462409 282.9194495309215 +r_0478 glutaminyl-tRNA synthetase 0.0020626521482291 1.5240030427131136e-05 0.73885606161053 0.003506490744062 2.1632984150308203e-05 0.6169411451304118 0.009682649502322 2.7281407453844148e-05 0.2817556026096122 0.0162557482155842 4.400986164647058e-05 0.2707341493163552 0.0175051906306947 7.37048263103103e-05 0.4210455508040657 0.0245082803324369 7.138340970314987e-05 0.2912624171703843 0.0283817139077332 0.0001340942613296 0.4724671024644454 0.0357185075795214 0.0002096810264506 0.5870374790541951 0.0377938690494765 0.0001902782579762 0.5034632938141206 +r_0479 glutamyl-tRNA synthetase 0.004332309092276 3.20095283359865e-05 0.7388560616105448 0.0073648878438005 4.543702340111679e-05 0.6169411451304517 0.0203370357489726 5.730073762745872e-05 0.281755602609655 0.0341428998857538 9.243648955763534e-05 0.2707341493163695 0.0367671769554017 0.0001548065627269 0.4210455508040596 0.0514761763448252 0.0001499307554888 0.2912624171703545 0.0596117757046059 0.0002816460293991 0.4724671024644492 0.0750216730834393 0.0004404053384132 0.5870374790541621 0.0793806763083713 0.000399652567594 0.5034632938140882 +r_0480 glutamyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0481 glutathione oxidoreductase 1.385109402225802e-05 0.0005652573416735 4080.9580872469696 4.201680225822418e-05 0.0013281105724955 3160.9034983988013 1.4209454135383047e-05 0.000710018112858 4996.800764429195 5.243682086413459e-05 0.0016573632850491 3160.686055593409 4.1890383260985306e-05 0.0020939377672454 4998.612101970426 3.4240397421190105e-05 0.0017109734702427 4996.943958319436 0.0001573104391389 0.0049725791762476 3160.997581257001 0.0001433396429579 0.0058497417355784 4081.035514573431 0.0001377045512713 0.0056196184307463 4080.924253311691 +r_0482 glutathione oxidoreductase 9.909999999999615e-10 9.654462270284212e-11 9.742141544182228 9.91399999999961e-10 9.448717143142752e-11 9.530680999740891 9.923999999999611e-10 8.685475663284618e-11 8.751990793314146 9.91300018127075e-10 9.368036687556928e-11 9.4502537236472 9.939999999999606e-10 7.723466215766086e-11 7.770086736183495 9.951999999999601e-10 6.912246800510071e-11 6.945585611445286 9.92199999999961e-10 8.798129427115725e-11 8.867294322834178 9.9419999999996e-10 7.594414725770619e-11 7.63871929769757 9.975999999999592e-10 4.8935865618058276e-11 4.905359424424647 +r_0483 glutathione peridoxase 1.3850374734568576e-05 0.0005652573429635 4081.170031830981 4.201596851345579e-05 0.0013281105735632 3160.966224396088 1.4208520319212307e-05 0.0007100181215404 4997.129226612062 5.243628987934501e-05 0.0016573632828703 3160.718057444411 4.188976458876484e-05 0.0020939377696215 4998.6859324179095 3.423961646269094e-05 0.0017109734658588 4997.057918926093 0.0001573096223491 0.0049725791704509 3161.013990240819 0.0001433388040721 0.0058497417397979 4081.059401649313 0.0001377036864922 0.0056196184356002 4080.949885039353 +r_0484 glutathione peroxidase, mitochondria 9.909999999999615e-10 9.654462270284212e-11 9.742141544182228 9.91399999999961e-10 9.448717143142752e-11 9.530680999740891 9.923999999999611e-10 8.685475663284618e-11 8.751990793314146 9.91300018127075e-10 9.368036687556928e-11 9.4502537236472 9.939999999999606e-10 7.723466215766086e-11 7.770086736183495 9.951999999999601e-10 6.912246800510071e-11 6.945585611445286 9.92199999999961e-10 8.798129427115725e-11 8.867294322834178 9.9419999999996e-10 7.594414725770619e-11 7.63871929769757 9.975999999999592e-10 4.8935865618058276e-11 4.905359424424647 +r_0485 glutathione synthetase 6.643968385163965e-05 0.0015055469846774 2266.035744600102 0.0001597708076996 0.0031760484579648 1987.8778255511684 6.03942404550051e-05 0.0017691610238824 2929.353876385727 0.0001612263977387 0.0034947161852531 2167.583121789103 0.000178774995452 0.0052330619018165 2927.1777569256287 0.0001278951590164 0.004077057629814 3187.812315310656 0.0002672900079628 0.0078216547187569 2926.280252063776 0.0006114442105296 0.0152684200214992 2497.107627901856 0.0003917238987938 0.0114686018552466 2927.725852458861 +r_0486 glyceraldehyde-3-phosphate dehydrogenase 0.5342630423283801 0.0476553050745317 8.919820631209001 0.7785240397424105 0.0804937257450293 10.339272987853048 1.8622753879515697 0.1317762888232619 7.0760903395824135 2.611024748943813 0.1812734430724443 6.942616807664168 3.651245631897685 0.3697394575997529 10.126392329501696 4.455223654005887 0.2806911794933977 6.300271350934672 5.076996678381364 0.4404610475515437 8.675622133595141 8.706819517746576 0.7378059268658352 8.473885617612845 12.41596839905295 0.6310225229247624 5.082346399761252 +r_0487 glycerol dehydrogenase (NADP-dependent) 6.962772464308922e-10 5.204055336217296e-10 74.74113742612172 4.697359804675947e-10 5.69325346812582e-10 121.2011364864688 4.2169515335932254e-10 5.891344019177682e-10 139.70623025296482 4.999605312669332e-10 5.804410127550675e-10 116.09736698298792 6.23383160221225e-10 6.434579957079412e-10 103.22030442394244 6.83331962692951e-10 5.391446802294085e-10 78.89937975456132 5.421241484668482e-10 6.136923435527275e-10 113.20144016610904 5.111541396354587e-10 5.450066270117437e-10 106.62275520265332 5.634000000000262e-10 5.230058766681517e-10 92.83029404830096 +r_0488 glycerol kinase 0.0004564554800239 0.003741069726354 819.5913709170684 0.0006663095654142 0.0052259263557703 784.3090699923166 0.0005942687690992 0.0052837612718108 889.1197967242734 0.0009733842699416 0.0078102713795265 802.3831513112908 0.0019071408505147 0.0160956697760095 843.9685916048088 0.0016785858186848 0.0137830814722805 821.1127080222254 0.0028006065617665 0.0223585514152245 798.3467481816309 0.004322908480763 0.0367062594666507 849.1102606033287 0.0046463319644132 0.0370403281797322 797.1950446810041 +r_0489 glycerol-3-phosphatase 0.0001620278083394 0.0030203130175448 1864.070771862336 8.862746892567873e-05 0.0033029396139077 3726.767393839887 0.0001778316136995 0.0042665533186259 2399.209696108092 0.0002172698540435 0.0058205297555316 2678.9403348905944 0.0004847344433567 0.0125257821294242 2584.0503601693617 0.000467830826436 0.0109489663370096 2340.3687226894435 0.0005373453224949 0.0159204375453019 2962.794478489747 0.0010775033255174 0.0285676487518978 2651.2817246460418 0.0011620129077067 0.0287510174404949 2474.2425191502025 +r_0490 glycerol-3-phosphate dehydrogenase (fad) 0.0043529355333984 0.0902394433367801 2073.0709803627165 0.0078497777963683 0.1626748012820892 2072.349122510819 0.0189277846676617 0.3213687987261192 1697.8679986526852 0.0314521690311627 0.5349878167064711 1700.9568280534356 0.0390788218140191 0.703107020859507 1799.202197562861 0.0352710134897654 0.6838011243301308 1938.705630130385 0.0930160043607437 1.109097067040823 1192.3722962119664 0.052243754237669 1.010691696849014 1934.5694267129825 0.0712372173441431 1.2364597443575225 1735.693490643034 +r_0491 glycerol-3-phosphate dehydrogenase (NAD) 0.0040762991358515 0.0670854262860111 1645.7434562637018 0.0070210012867053 0.121044086815785 1724.0288368126112 0.0176151960209352 0.2482340822930386 1409.2042007254354 0.026705334803855 0.3928796667847563 1471.16547937097 0.0342741315380393 0.5164971628075399 1506.9591544115517 0.0350394986953684 0.5069678850421823 1446.8468554579902 0.0750411011994465 0.7593072967788478 1011.8552161977713 0.03897199973309 0.5088178800110205 1305.5985925684915 0.0651740269451623 0.9211630205325202 1413.3897561793908 +r_0492 glycerol-3-phosphate dehydrogenase (NAD) 0.0018075336918454 0.0559706127904063 3096.5183688089537 0.0032067234648962 0.0996816196537441 3108.519357685492 0.0071656608253023 0.1901296902170857 2653.3448184670883 0.0134472407475249 0.3355750957086763 2495.4940720492573 0.0168997763286943 0.4498447293501456 2661.838361649495 0.0147713044547307 0.4234969033715418 2867.024403087901 0.0339932122088944 0.7578332841864707 2229.3664968448634 0.0317846712280613 0.7924103836677212 2493.058298391756 0.0272271989298852 0.7029945833930727 2581.9570540598247 +r_0497 glycerophosphodiester phosphodiesterase (glycerophosphocholine) 0.0001126349313041 0.0011590505962448 1029.032985437829 0.0001637662340709 0.0018838331673498 1150.3184267728773 0.0002033559302432 0.0018476498351152 908.5792742336145 0.0002215158386296 0.0024116984549001 1088.7250635526177 0.0004627435947353 0.004999408731164 1080.384210185145 0.0003748727688285 0.0040201469095357 1072.4030241243158 0.0007260218759572 0.0076373937344315 1051.9509104820552 0.0009774791393881 0.0109651376184308 1121.777148645277 0.0009218730457079 0.0102412014211354 1110.9123396997409 +r_0499 glycinamide ribotide transformylase 0.0023449246804801 0.0002829338294029 12.065796047016931 0.0038719214958873 0.0010230903188197 26.423322887782422 0.00886208077158 0.0008362145130136 9.435871039398544 0.0131844677905472 0.0013270928310142 10.065577557599688 0.0186309699037152 0.0024674059688484 13.243572297094316 0.0219398447660159 0.0011162616427227 5.087828353515831 0.0247854152299604 0.0039229085691191 15.827487789581795 0.0292495167731632 0.0061419597153137 20.99849978017101 0.0330699098225629 0.0059229816578712 17.91048626878961 +r_0500 glycine C-acetyltransferase 3.934000000000132e-10 5.421210372636451e-10 137.80402574062714 7.318000000000387e-10 4.612063553990291e-10 63.0235522545784 9.275999999999835e-10 2.6452265393891315e-10 28.51688809173328 5.664000000000262e-10 4.988394613115928e-10 88.07193879088447 5.690000000000264e-10 4.976831700063206e-10 87.46628646859364 4.772000000000195e-10 5.520336114963043e-10 115.68181297072128 3.9260000000001315e-10 4.900135331320071e-10 124.81241292205569 1.8959999999999803e-10 3.9910361654507327e-10 210.4976880512012 6.622000000000332e-10 4.742743375193925e-10 71.62101140431422 +r_0501 glycine cleavage system 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0502 glycine hydroxymethyltransferase 0.0099536530047277 0.0030891297211039 31.035135739980657 0.0189597818801048 0.0044383515593336 23.409296517229063 0.0476246401644825 0.0051313941744421 10.774662352764777 0.0679380021098463 0.0073414812394106 10.806148269624485 0.0866655340334488 0.0134103405212013 15.473672055174276 0.0953328906732061 0.0100857381090583 10.57949469258362 0.118519109847104 0.0202282682745577 17.067516201103214 0.1401187658695218 0.0311358313367734 22.221028813347573 0.1550683501137963 0.0300650474385669 19.388255189730103 +r_0503 glycine hydroxymethyltransferase 4.314561390055937e-06 3.116430246675805e-08 0.7223052275622857 7.030197281913983e-06 4.309647880535063e-08 0.6130194797836104 1.6327603715617497e-05 4.5747896773372726e-08 0.2801874516933214 2.427232206159556e-05 6.579710648065181e-08 0.2710787468692915 3.422407747610143e-05 1.4387395899918422e-07 0.4203881290873391 4.056400216767678e-05 1.1842347139034885e-07 0.2919422765555268 4.54135631021913e-05 2.143804144113621e-07 0.4720625288285687 5.333341737548827e-05 3.128689255311628e-07 0.5866283109676665 6.047393405798335e-05 3.0423285281545295e-07 0.5030809679485211 +r_0504 glycine-cleavage complex (lipoamide) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0505 glycine-cleavage complex (lipoamide) 0.2570514953227088 0.041250172374932 16.047435290405744 0.4206959234545128 0.0803620165321932 19.10216193023849 0.5625845839429333 0.1057386380974022 18.79515385159008 0.9116500452284146 0.2081965466764561 22.83733190890068 1.2191777160071438 0.3125867279353267 25.63914381236075 1.619236585900537 0.2591089894004335 16.00192286023047 1.9952435740722632 0.3695809127440172 18.52309750782497 2.4501116041961133 0.549000537487808 22.40716449600001 1.6857335347189208 0.5460796092784829 32.3941831868188 +r_0506 glycine-cleavage complex (lipoylprotein) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0507 glycine-cleavage complex (lipoylprotein) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0508 glycine-cleavage complex (lipoylprotein) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0509 glycine-cleavage system (lipoamide) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0510 glycogen (starch) synthase 0.011242158788089 0.0074559173987552 66.32104686739265 0.0174609638956292 0.0089846005117103 51.45535243881542 0.0353228290597891 0.0095074550515282 26.915893501722177 0.0469717401819713 0.0156701227970745 33.36074570873372 0.083449656312343 0.0298022660148071 35.7128684907467 0.0865967048509502 0.024293710408852 28.05385083724176 0.0955370774217712 0.0485651481304945 50.833822261583386 0.1049489828950653 0.0620210612899151 59.096391007360005 0.1273153649754537 0.066594308083291 52.30657595501563 +r_0511 glycogen phosphorylase 0.0004870438886566 0.0073270304193913 1504.3881239534965 0.0003628297946967 0.008545128218481 2355.134099618916 0.0005108639601418 0.009313994332862 1823.1848514573528 0.0009559770930386 0.0154800538653864 1619.2912966337517 0.0016070983414332 0.0283671026535165 1765.1130563807374 0.0013132987234927 0.0231812054887197 1765.1129232097935 0.0030188564589655 0.0476415916070888 1578.1337156856512 0.002978882240815 0.058350538861409 1958.806496675844 0.0037428249243343 0.0640861146433915 1712.239175995919 +r_0512 glycyl-tRNA synthetase 0.0041461750625913 3.0634265774943576e-05 0.7388560616106141 0.0070484616093508 4.3484859766808535e-05 0.6169411451304422 0.0194632720504069 5.483885945317616e-05 0.2817556026096326 0.0326759788038326 8.846503324536435e-05 0.2707341493164025 0.0351875060083185 0.0001481554284869 0.4210455508041466 0.0492645455650838 0.0001434891062208 0.2912624171703811 0.057050605715989 0.0002695453437647 0.4724671024644133 0.0717984297674016 0.000421483692107 0.5870374790541465 0.0759701520715963 0.0003824818299352 0.5034632938141692 +r_0514 GMP synthase 0.00110453676586 0.0004357992982182 39.45539086505149 0.0018131622809654 0.000955482546332 52.697023116059285 0.0041476078561209 0.0006645057085973 16.021420820116138 0.0061611325799764 0.0009939107710672 16.1319490883447 0.0087102040272095 0.0020258181782704 23.25798766529534 0.0102880692738896 0.0013502626833852 13.124548906490713 0.0115833928022394 0.0034019474989074 29.369180144264533 0.0136892395058592 0.0054430313472479 39.76138590400339 0.0154437358826827 0.0046238007659548 29.939651915049577 +r_0518 GPI-anchor assembly, step 2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0519 GPI-anchor assembly, step 5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0520 GPI-anchor assembly, step 6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0521 GPI-anchor assembly, step 7 2.4170206322881084e-11 5.39303585559778e-10 2231.274232232094 3.722983009871203e-11 4.5798014384239685e-10 1230.142986492546 5.0895566683240187e-11 3.5787819565977206e-10 703.1618252471894 2.957981694381128e-11 4.930091141703685e-10 1666.707793043041 6.000000000000003e-13 3.1620246172249005e-11 5270.041028708167 -2.543452158537961e-12 1.0301282187805895e-10 -4050.118321756572 2.240788476693714e-11 3.763576524610084e-10 1679.576882760146 1.3764958235643927e-11 4.3270944567132444e-10 3143.5579989689822 -7.766949842028122e-12 2.986629252964699e-10 -3845.305188921916 +r_0522 GPI-anchor assembly, step 8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0523 GPI-anchor assembly, step 9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0524 GTP cyclohydrolase I 1.4369957721759477e-06 2.1435157551801863e-09 0.1491664621903794 2.3423345049184554e-06 2.3253499579600802e-09 0.0992748880690306 5.444508710494739e-06 2.4191601629719702e-09 0.0444330295276934 8.098384123110852e-06 2.168578873457409e-08 0.2677792063812834 1.1419280920420373e-05 4.782435801770063e-08 0.4188035862414014 1.3534823348019532e-05 3.917077379741452e-08 0.2894073516160529 1.515289005932632e-05 7.131036662460012e-08 0.4706057151170968 1.7795862689727744e-05 1.041969499418364e-07 0.585512215724061 2.017846472700183e-05 1.0145823451235229e-07 0.5028045289123799 +r_0525 GTP cyclohydrolase II 2.271524373492777e-05 1.6789948919537965e-07 0.7391489660188474 3.700710460573424e-05 2.2842819800148698e-07 0.6172549850497953 8.593981847370837e-05 2.421549633201476e-07 0.2817727191199853 0.000127752127615 3.45894744584255e-07 0.2707545862771189 0.0001801328257654 7.585244344111522e-07 0.4210917311644888 0.0002135013600163 6.215664813219225e-07 0.2911299868414467 0.000239022656492 1.1292799168216456e-06 0.4724572696978615 0.0002807095357251 1.6477928317304747e-06 0.5870099237895662 0.0003182893608867 1.6024667769665333e-06 0.5034622497284286 +r_0526 guanine deaminase 1.421290634975943e-05 0.0004357814430515 3066.0966330711963 3.68475470323911e-05 0.0009555088281529 2593.140941819005 2.2615450678302463e-05 0.000664487074063 2938.1995676989754 2.9213131686195903e-05 0.0009938752868273 3402.1524891732083 6.410087625039799e-05 0.0020257402196724 3160.2379533148955 4.0412494805320176e-05 0.0013501351359265 3340.8853930711607 0.0001106962547268 0.0034019115907591 3073.1948421872053 0.0002156608438244 0.0054431414667427 2523.935903345839 0.0001663763933066 0.0046237659446823 2779.0997585576115 +r_0527 guanine phosphoribosyltransferase 2.603709407749639e-05 0.0010628414633772 4082.027972145576 9.308342385425924e-05 0.0026929845758825 2893.087151691924 1.362363861726161e-05 0.0009634244327925 7071.711602595373 9.920185390377022e-05 0.0031371370462293 3162.377438301165 7.819530882050294e-05 0.0039109305834159 5001.490041293252 0.0001265385125266 0.0044757284472062 3537.04841145666 0.000532521863854 0.0125448600951809 2355.7455471195804 0.0003666978929147 0.0129608734108155 3534.482652134688 0.000428219533199 0.0135394060622818 3161.790860200635 +r_0528 guanylate kinase 0.0003937042005755 0.0049933953915434 1268.3114338743917 0.0004486978699354 0.0070421304861317 1569.4593083636162 0.0006040118038459 0.0064897107952533 1074.4344322298757 0.0009345269452492 0.0112701395868513 1205.9726735696397 0.0012207288123392 0.0183245375800944 1501.1145305057537 0.001703439330233 0.0170059172204984 998.328318401117 0.0029332622215525 0.0322029744633937 1097.855289812769 0.0032187336817948 0.0436201100120964 1355.1947543473825 0.0024730736813745 0.0401865953174508 1624.965548746388 +r_0529 guanylate kinase (GMP:dATP) 6.294184395561664e-06 0.00191253589161 30385.76202118668 8.221479949990296e-05 0.0038035775431019 4626.390341201876 6.509995234579614e-05 0.0027877935220708 4282.328053425834 0.000377269372516 0.0047533603586578 1259.9380455820394 0.0004745117542507 0.0115129453293004 2426.271894461217 -1.193074456541429e-05 0.0066382797576396 -55640.11299750035 0.0001970787689901 0.0123458263513882 6264.412150861846 0.0005596786956833 0.0322200202003488 5756.878088955837 0.001094594652083 0.0231030055380547 2110.6448395385405 +r_0530 heme O monooxygenase 1.3958301013697196e-05 0.0001439642894916 1031.3883426814464 8.005891317926721e-06 0.0001060046000509 1324.082426820108 1.442112067883581e-05 0.0001678546714673 1163.9502588293217 1.3929719867077416e-05 0.0002030935302796 1457.987182927427 4.5321993977749794e-05 0.000513016162131 1131.9364332975897 3.8587116727232353e-05 0.0004661301435597 1207.9942299259296 4.060587165422495e-05 0.0005824694663705 1434.4464055113838 9.34688555710928e-05 0.0011187945380192 1196.9704038670634 9.266253253933534e-05 0.0010814233637298 1167.055695645665 +r_0531 Heme O synthase 1.3958301013697196e-05 0.0001439642894916 1031.388342681446 8.005891317926721e-06 0.0001060046000509 1324.082426820108 1.442112067883581e-05 0.0001678546714673 1163.9502588293217 1.3929719867077416e-05 0.0002030935302796 1457.987182927427 4.5321993977749794e-05 0.000513016162131 1131.9364332975897 3.8587116727232353e-05 0.0004661301435597 1207.9942299259296 4.060587165422494e-05 0.0005824694663705 1434.4464055113838 9.34688555710928e-05 0.0011187945380192 1196.9704038670634 9.266253253933534e-05 0.0010814233637298 1167.0556956456646 +r_0532 hexaprenyldihydroxybenzoate methyltransferase -3.573787597845846e-10 2.9275360457156436e-10 -81.91690092271459 -3.4303333333472275e-10 5.726070188001363e-11 -16.692459978558457 -3.1193333333335736e-10 2.2970351292890388e-10 -73.63865556600328 -3.4893333332778447e-10 6.334822929933154e-11 -18.154823070406646 -3.4286666666670365e-10 9.871371621230294e-11 -28.79070082022913 -2.9193333326997896e-10 2.3654341273915874e-10 -81.02651728379513 -2.766333333439456e-10 1.9179914449239078e-10 -69.33334539765018 -2.6873333333604863e-10 3.2636606690790473e-10 -121.44606806174912 -3.3896666667221235e-10 1.493707359817665e-10 -44.06649699458826 +r_0533 hexokinase (D-fructose:ATP) 1.2187999999999034e-09 6.376581228027504e-10 52.318520085559626 1.451399999999879e-09 8.393920155631331e-10 57.83326550662831 1.2889999999998923e-09 7.665484455034903e-10 59.468459697715616 1.3021999999998955e-09 7.476543033992674e-10 57.41470614339791 1.1461999999999231e-09 5.265747963995532e-10 45.94091750127281 1.1161999999999261e-09 4.971388029493031e-10 44.53850590837986 1.2333999999999035e-09 7.39076238785488e-10 59.92186142253493 1.2737999999998994e-09 8.100399946660927e-10 63.59240027211155 1.2843999999998983e-09 7.367667236249484e-10 57.36271594713538 +r_0534 hexokinase (D-glucose:ATP) 0.3731849381494696 0.0134413811391194 3.6018016176568737 0.5698934215486541 0.0112161621791014 1.96811574848892 1.3104031232429891 0.0438957974512198 3.3497934088089187 1.8567709580533864 0.01115156797571 0.6005893148717296 2.706446723849022 0.1214499684548324 4.487432447297915 3.12874007306991 0.0498471380933736 1.5932016380147482 3.5946543058996934 0.1357301968763699 3.775890122552368 5.567944459578667 0.2448022439623341 4.396635881329511 7.676093857957565 0.2758752151366377 3.593953125659695 +r_0535 hexokinase (D-mannose:ATP) 8.593638406801562e-11 1.3389797153810355e-09 1558.1057195998385 1.7260818273328223e-10 4.5251461577684947e-10 262.1628990069865 2.600000000000001e-12 5.09289578898884e-11 1958.8060726880149 2.239999999999997e-11 1.4799533953508704e-10 660.6934800673538 3.200000000000001e-12 6.317086442041264e-11 1974.0895131378943 6.438250228634859e-11 2.7002958251915104e-10 419.4145504288781 2.800000000000001e-12 5.2846178137199376e-11 1887.363504899977 3.8e-12 6.153305829757655e-11 1619.2910078309617 5.599999999999999e-12 7.463078420323796e-11 1332.692575057821 +r_0536 histidinol dehydrogenase 0.0012210916495135 9.021915664957767e-06 0.7388401737537227 0.0020758457726323 1.2806641325380631e-05 0.6169360698285827 0.0057321391948142 1.615044930246556e-05 0.2817525665998569 0.0096234216341494 2.6053707717273056e-05 0.2707322687059599 0.0103630930381961 4.3633159732137694e-05 0.4210437904138785 0.0145089307625603 4.225885128841649e-05 0.2912609618171428 0.016802007996193 7.938376433836461e-05 0.4724659359545068 0.021145398788512 0.0001241312286921 0.5870365933205264 0.0223740152409561 0.0001126447632292 0.5034624407649516 +r_0537 histidinol-phosphatase 0.0012210916495135 9.021915664957767e-06 0.7388401737537229 0.0020758457726323 1.2806641325380631e-05 0.6169360698285827 0.0057321391948142 1.615044930246556e-05 0.2817525665998569 0.0096234216341494 2.6053707717273056e-05 0.2707322687059599 0.0103630930381961 4.3633159732137694e-05 0.4210437904138785 0.0145089307625603 4.225885128841649e-05 0.2912609618171428 0.016802007996193 7.938376433836462e-05 0.4724659359545069 0.021145398788512 0.0001241312286921 0.5870365933205264 0.0223740152409561 0.0001126447632292 0.5034624407649517 +r_0538 histidinol-phosphate transaminase 0.0012210916495135 9.021915664957767e-06 0.7388401737537229 0.0020758457726323 1.2806641325380631e-05 0.6169360698285827 0.0057321391948142 1.615044930246556e-05 0.2817525665998569 0.0096234216341494 2.6053707717273056e-05 0.2707322687059599 0.0103630930381961 4.3633159732137694e-05 0.4210437904138785 0.0145089307625603 4.225885128841649e-05 0.2912609618171428 0.016802007996193 7.938376433836461e-05 0.4724659359545068 0.021145398788512 0.0001241312286921 0.5870365933205266 0.0223740152409561 0.0001126447632292 0.5034624407649516 +r_0539 histidyl-tRNA synthetase 0.0012210925692029 9.02211646543091e-06 0.7388560616104828 0.00207584676613 1.2806752810114945e-05 0.6169411451303828 0.0057321402290894 1.6150626244897837e-05 0.2817556026095935 0.0096234226260208 2.605389138168181e-05 0.270734149316424 0.0103630940485858 4.363334641721744e-05 0.4210455508041226 0.0145089316313312 4.225906497502032e-05 0.2912624171704289 0.0168020089978473 7.938396506794401e-05 0.4724671024644417 0.0211453997349048 0.0001241314215397 0.5870374790541842 0.0223740162379566 0.0001126449591101 0.5034632938141423 +r_0540 histidyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0541 hnRNP arginine N-methyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0542 homoacontinate hydratase 0.0048132272607936 3.5562686012007606e-05 0.7388532492883723 0.0081824452387841 5.0480819421499503e-05 0.6169405104262032 0.0225945993771964 6.366146575899787e-05 0.2817552313994466 0.0379330185749148 0.0001026975097591 0.270733818760794 0.0408486101048924 0.0001719910494753 0.4210450466582642 0.0571904194436072 0.0001665740527099 0.2912621630170618 0.0662291317364671 0.0003129107706179 0.4724669679546817 0.0833496439463349 0.0004892934872609 0.587037285457352 0.0881925294363884 0.0004440169619329 0.5034632352315446 +r_0543 homocitrate synthase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0544 homocysteine S-methyltransferase 3.2873103554112505e-05 0.0009487096138295 2885.97519326982 5.038871801960935e-05 0.0015927855387091 3160.9963525750354 6.706604550444013e-05 0.0016763052942418 2499.484324196252 7.507789807282032e-05 0.0021663798650765 2885.509478402449 0.0001748059726424 0.0046693614267024 2671.1681277918 6.0602944338350586e-05 0.0024739575552991 4082.239868556399 0.0002264587486512 0.0065340308154899 2885.3073040484355 0.0004573704001218 0.0114263700754697 2498.2749369934468 0.0004953742782214 0.0116667369329412 2355.1357924415056 +r_0545 homoisocitrate dehydrogenase 0.0048132272678945 3.5562684486273145e-05 0.7388532164995626 0.0081824452783838 5.048081107739071e-05 0.6169404054647253 0.0225945994042616 6.366146008867058e-05 0.2817552059660024 0.037933018595403 0.000102697505425 0.2707338071890211 0.0408486101048924 0.0001719910494753 0.4210450466582642 0.057190419443427 0.0001665740527508 0.2912621630893741 0.0662291317367562 0.000312910770553 0.4724669678545902 0.0833496440291107 0.0004892934691728 0.5870372631728625 0.0881925295362536 0.0004440169401032 0.5034632099090739 +r_0546 homoserine dehydrogenase (NADH) 0.0053676200278084 0.0018670892619959 34.78430388744051 0.0090624857094658 0.0027654101708707 30.51491896955248 0.0247074980544202 0.0043985284990536 17.802403502635183 0.0416195923159559 0.006910697578326 16.604433618338557 0.0449449073451765 0.0118207252605798 26.30047753752562 0.0624033952459456 0.0087552145761316 14.03002920213786 0.073063692922969 0.0200546614976038 27.44819033271077 0.0921423522343997 0.0282705013174038 30.68133234268529 0.0966926120146911 0.0263376848079777 27.23856999951157 +r_0547 homoserine dehydrogenase (NADP) 1.947604264033611e-05 0.0005208682992165 2674.405210726907 1.602882452938337e-05 0.0007434522122011 4638.220418710809 7.397512279857889e-05 0.0017677802345912 2389.695572935477 0.0001349009014753 0.0026211230000906 1942.9988765275173 0.0003290753327888 0.0054965580347711 1670.303874857311 0.0002032129577635 0.0049369530727224 2429.447967814885 0.0005298883711869 0.0083900601312403 1583.3637021410134 0.0006798503682764 0.010735600295433 1579.112227687628 0.0009703592294159 0.0138236688852835 1424.5929204593974 +r_0548 homoserine kinase 0.0035554237539221 0.0014893490373532 41.88949448600348 0.0059933645760891 0.0023569370866125 39.325775308509 0.0164856545207451 0.003992407429455 24.217463883105538 0.027747923354797 0.0057008529597923 20.545151746668537 0.0301881080222792 0.0109578585356316 36.29859323262191 0.0415594698069871 0.0073532288012708 17.69326903211514 0.0490119747808532 0.017977275919901 36.6793543828475 0.0620192780309862 0.0264247527108737 42.60732073932135 0.0652199077805943 0.0250444428629812 38.39999735545941 +r_0549 homoserine O-trans-acetylase 0.0018178837389305 0.0010175569635374 55.97480970571159 0.0030479540206958 0.0011954998600289 39.223028034917256 0.0082781571692716 0.0015074896883661 18.210450194904755 0.0139562523861842 0.0028616109261356 20.50415001786945 0.0150337842779042 0.0038017524811811 25.28806061670575 0.021030103023137 0.0045546924826628 21.65796562029133 0.0244258085937977 0.0066777959672236 27.339098894434706 0.0307435062644323 0.0087692928591753 28.52404922115419 0.0323861889885847 0.0075192250824334 23.21738159770445 +r_0550 hydrogen peroxide reductase (thioredoxin) 1.385055976527001e-05 0.0005652569350347 4081.112565949131 3.6272209641711286e-05 0.0012027201359528 3315.8171168314075 3.486070348443148e-05 0.0011027101259994 3163.189539453601 4.513978384179024e-05 0.0014987068135763 3320.146190396272 0.0001409768701567 0.00378340496953 2683.706174867048 4.095959847311832e-05 0.001732650668284 4230.145638320077 9.443882259657456e-05 0.003854332374859 4081.300749929941 0.0002740150449255 0.0079478065352644 2900.5000573692014 0.0002294770573978 0.0072534338882513 3160.8536254130013 +r_0551 hydrogen peroxide reductase (thioredoxin) 9.919999999999612e-10 9.131082922362471e-11 9.204720687865755 9.91399999999961e-10 9.44871714314276e-11 9.530680999740898 9.92199999999961e-10 8.798129427115606e-11 8.867294322834057 9.911999999999614e-10 9.340398739332864e-11 9.423323990449182 9.937999999999603e-10 7.850345571063571e-11 7.899321363517692 9.951999999999601e-10 6.912246800509983e-11 6.945585611445197 9.91399999999961e-10 9.234579334820406e-11 9.314685631249512 9.9419999999996e-10 7.594414725770619e-11 7.63871929769757 9.97199999999959e-10 5.284617813720442e-11 5.299456291336399 +r_0552 hydrogen peroxide reductase (thioredoxin) 3.3800481661590666e-05 0.0006715450740156 1986.791433149108 7.0695908405003e-05 0.0012983497706094 1836.527459512104 5.700040373303183e-05 0.0010860673141039 1905.3677570261648 3.904822450060782e-05 0.001060505117616 2715.885629062554 8.100853527509963e-05 0.0021618013421443 2668.609344438842 0.0001362210735211 0.0025687141016721 1885.6950949470977 0.0001696565850694 0.0038609790526018 2275.7613864628006 0.0001893768806827 0.0050067003382005 2643.7759034523324 0.0002345934934585 0.0055228399777603 2354.2170314861787 +r_0553 hydroxyacylglutathione hydrolase 4e-13 1.9997999499870408e-11 4999.499874967602 2.0000000000000004e-12 4.468108413921743e-11 2234.0542069608714 6.000000000000003e-13 2.448999697816333e-11 4081.6661630272206 3.999825807060149e-13 2.8284887502209288e-11 7071.529828194828 8e-13 2.8275782995007477e-11 3534.4728743759347 2e-13 1.4142135623728843e-11 7071.067811864423 1e-12 3.1610122428868876e-11 3161.012242886888 1.6e-12 3.997198458808681e-11 2498.249036755425 2e-13 1.4142135623730082e-11 7071.06781186504 +r_0554 hydroxyacylglutathione hydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0555 hydroxybenzoate octaprenyltransferase 7.822465069860881e-10 6.938087219668316e-10 88.69438415775129 7.90449561435883e-10 1.5829857838973847e-09 200.2639840829095 8.207892748286725e-10 1.3643281506059452e-09 166.22148856546983 7.812999999712787e-10 4.162123667379482e-10 53.27177355090854 8.167396187146554e-10 5.457842718724277e-10 66.82475777670194 8.241174790425943e-10 4.025537799413841e-10 48.84664992290234 7.93944218459268e-10 7.750497096279875e-10 97.6201717460772 8.072836757657396e-10 4.140462956313487e-10 51.28882300742795 7.420672707783386e-10 6.287802349374792e-10 84.73358948683517 +r_0556 hydroxyethylthiazole kinase 7.19409952798757e-05 0.0014097114871494 1959.53848242606 7.98504164374737e-05 0.0019591278226931 2453.497314227807 7.662629027843902e-05 0.0018046556712518 2355.1390321705485 0.0001006357653787 0.0025141496766502 2498.266562774324 0.0002985345383105 0.0060901042783816 2039.99989845276 0.0002362102688146 0.0048611648284648 2057.982005972884 0.0003774760929213 0.0084329394062282 2234.032714751154 0.0005156452240407 0.0121441683541173 2355.140276283824 0.0004952607052135 0.0116640890099667 2355.141218994412 +r_0557 hydroxymethylbilane synthase 1.395825128638109e-05 0.0001439643589443 1031.3925146542088 8.00589842634533e-06 0.0001060046086754 1324.0813588962028 1.44197537700597e-05 0.0001678548455166 1164.0618015623809 1.3930564342544362e-05 0.0002030935084563 1457.8986425987962 4.532279065521537e-05 0.0005130161656274 1131.9165439969725 3.85879621442002e-05 0.0004661301422831 1207.9677608816532 4.0606739097514856e-05 0.0005824694860823 1434.4158113350682 9.346966994326816e-05 0.001118794512622 1196.9599478644732 9.26633394698876e-05 0.0010814233868257 1167.045557620077 +r_0558 hydroxymethylglutaryl CoA reductase 0.0053001906480806 0.0018711292439558 35.303055459588755 0.0083367862376668 0.0011828775915692 14.188652051852454 0.0192965990028716 0.002048450636081 10.61560452065254 0.0286193723832947 0.0026701614973804 9.329909341195169 0.0407809096081129 0.0061833091913512 15.162264036702927 0.0480584479286974 0.0057014975418115 11.863673896149596 0.0542910123576858 0.0101436805416246 18.683903838069867 0.0639823804599395 0.0129443223468359 20.23107338893176 0.0724009683014875 0.0141460310987399 19.538455673457204 +r_0560 hydroxymethylglutaryl CoA synthase 0.0053001906425731 0.0018711292447856 35.3030555119294 0.0083367862376668 0.0011828775915692 14.188652051852454 0.0192965990029422 0.0020484506360708 10.615604520561078 0.0286193723832947 0.0026701614973804 9.329909341195169 0.0407809096081129 0.0061833091913512 15.162264036702927 0.0480584479079542 0.0057014975449106 11.863673907718889 0.054291012339274 0.0101436805442741 18.683903849286303 0.0639823804577732 0.0129443223471626 20.23107339012736 0.0724009683014875 0.0141460310987399 19.538455673457204 +r_0561 hydroxymethylpyrimidine kinase (ATP) 7.195529956557966e-05 0.0014097117446915 1959.149295746732 7.985143966777673e-05 0.0019591277809915 2453.465822460491 7.672665080299656e-05 0.0018046557438041 2352.0585414810057 0.0001007887852572 0.002514149644466 2494.4736044275382 0.0002987499246133 0.0060901042843144 2038.5291451359687 0.0002364688851371 0.0048611647970297 2055.7312621536385 0.0003777625599592 0.0084329393640065 2232.338579269292 0.0005159827098879 0.0121441683209483 2353.5998567831866 0.0004956424166813 0.0116640889597066 2353.327432669213 +r_0562 hypoxanthine phosphoribosyltransferase (Hypoxanthine) 8.649548428596529e-06 0.0006116474216384 7071.437621139363 3.2250910364853066e-05 0.0016124194784678 4999.609190024715 9.534315823862492e-05 0.00252331496013 2646.5611237827 3.867658342054142e-05 0.0019350294833557 5003.103460084928 0.0003110457884199 0.0077731940447314 2499.051372538516 0.0001313296857246 0.0046418208693117 3534.4795380421792 8.626716023895267e-09 6.413183007833497e-07 7434.095419473097 9.971601375867324e-05 0.0065071615861013 6525.69365824184 9.713931936240498e-05 0.0062599912751048 6444.343357760462 +r_0563 Imidazole-glycerol-3-phosphate synthase 0.0012210917698947 9.021889892286491e-06 0.7388379902899314 0.0020758457702125 1.2806641836838498e-05 0.6169360951862611 0.0057321391952142 1.615044921867307e-05 0.2817525651183941 0.0096234216341494 2.6053707717273737e-05 0.270732268705967 0.0103630930381961 4.3633159732137694e-05 0.4210437904138785 0.0145089309295489 4.225881347571661e-05 0.2912606978481933 0.0168020079955813 7.938376447571934e-05 0.4724659367891984 0.0211453988103915 0.0001241312239128 0.5870365701112609 0.0223740152605143 0.000112644758955 0.5034624212216414 +r_0564 imidazoleglycerol-phosphate dehydratase 0.0012210916495135 9.021915664957767e-06 0.7388401737537227 0.0020758457726323 1.2806641325380631e-05 0.6169360698285827 0.0057321391948142 1.615044930246556e-05 0.2817525665998569 0.0096234216341494 2.6053707717273056e-05 0.2707322687059599 0.0103630930381961 4.3633159732137694e-05 0.4210437904138785 0.0145089307625603 4.225885128841649e-05 0.2912609618171428 0.016802007996193 7.938376433836461e-05 0.4724659359545068 0.021145398788512 0.0001241312286921 0.5870365933205264 0.0223740152409561 0.0001126447632292 0.5034624407649517 +r_0565 IMP dehydrogenase 0.0010943152122939 0.000126398113757 11.550430107982407 0.0017883538026752 0.0003804796202337 21.275410920623315 0.0041329038447245 0.0002796791412018 6.767133998505 0.0061379089782245 0.0002995890390917 4.880962558334579 0.008663837620395 0.0007243349433372 8.360439969836175 0.0102628136581714 0.0004795849507885 4.673035745969321 0.0114904673597026 0.0008895799775665 7.741895518422208 0.0135482014955652 0.0021915261396051 16.17577167214756 0.0153421206868119 0.0020478212620623 13.347706642815224 +r_0566 indole-3-glycerol-phosphate synthase 0.0007737518153022 0.0008148460998492 105.31104208537975 0.0012740322982829 0.0011740986210346 92.15611116115667 0.0032656281543926 0.0010881926658517 33.32261403944658 0.0053687698439837 0.0016457218085825 30.65361072288676 0.0061360165776296 0.0031701864750798 51.66522017944892 0.0082570269352965 0.0029871037225427 36.17650452093957 0.0095591523757171 0.0044449359943102 46.49926917789934 0.0121484645565081 0.0073750348900048 60.70754749046805 0.0129384841067491 0.0075400232207679 58.27593989032178 +r_0567 indole-3-pyruvate decarboxylase 2.379824811165685e-05 0.0004088231958652 1717.870970783864 2.898216659024926e-05 0.0004538778422244 1566.0590481084068 4.3643425637720784e-05 0.0006727799216066 1541.5378416701974 6.633694551556356e-05 0.0009985907792754 1505.3312622620042 9.305067404207188e-05 0.0016978645408706 1824.6665683506376 0.0001063543194217 0.0016788380485817 1578.533018413802 0.0001402622258414 0.0025163977315726 1794.066589544067 0.0002829397345753 0.0043477341188031 1536.6290370382667 0.0002569192087942 0.0041924152824018 1631.80297108886 +r_0568 inorganic diphosphatase 0.0004986120420769 0.0097720873787681 1959.8578762885256 0.0010068400917737 0.0178616746238729 1774.032914442915 0.0018582136011801 0.0241631251882748 1300.3416384924242 0.0022587102531015 0.0325205977199893 1439.7861644862787 0.0048755675350764 0.0677003423680727 1388.5633186498535 0.0029605111134971 0.0484346765806639 1636.0241432585017 0.0072933001070908 0.1033435416042735 1416.9654352190869 0.0092927620904015 0.1442957065914177 1552.7752156752176 0.0090077060862715 0.1387438394360072 1540.2793797575555 +r_0569 inorganic diphosphatase 0.2050441730236714 0.0210449207191055 10.263603402509744 0.3377498701609093 0.0374244097208295 11.08051046859024 0.7789069748748716 0.0375178085789315 4.816725204567414 1.1941141269269997 0.0539982087589936 4.522030812746156 1.5973835177128206 0.1087858266607444 6.810250979458401 1.9446546354888656 0.0836005228862624 4.298990749339209 2.22899725503226 0.1659605467477757 7.44552494953045 2.6897096627808006 0.2401492942098732 8.928446721702706 2.977561208999253 0.2336784799618854 7.847982411096223 +r_0570 inosine monophosphate cyclohydrolase 0.003566004419056 0.0002834971530417 7.949994439904984 0.00594776624287 0.0010232461697519 17.20387331930809 0.0145941195917143 0.0008366004472539 5.732448894888416 0.0228077364131908 0.001327619928126 5.820919288414068 0.0289938475461872 0.0024684595570266 8.513735726499933 0.0364485186474681 0.001118813452061 3.0695718058731445 0.0415871367804107 0.0039246505214889 9.437174148852613 0.0503945786134427 0.0061443996659881 12.1925807002366 0.0554435433877119 0.0059251960065963 10.686899942815634 +r_0571 inositol-1,3,4,5,6-pentakisphosphate 2-kinase 8.85854118559832e-05 0.0018062654408613 2039.010039031992 0.0001612583657858 0.003288043652938 2038.9910544572888 0.0001362403529252 0.0027779454774322 2039.0034360502248 0.0001695914617661 0.0037466267787462 2209.2071969479657 0.000267595920282 0.006685257147129 2498.2657209728804 0.0003009503487558 0.0064098734128093 2129.877383199316 0.0006028453642561 0.012292123340204 2039.0176435000053 0.0006875183469514 0.0161920052859611 2355.137918538416 0.0005857573303905 0.0146339719985448 2498.2994218419567 +r_0572 inositol-1,3,4,5-triphosphate 6-kinase, nucleus -1.2963397093551434e-10 1.0329030530514794e-09 -796.7842422765025 -5.780000000000001e-11 5.937420870488953e-10 -1027.2354447212722 -9.553745767944604e-11 6.312301520530195e-10 -660.714831004785 -6.693333333333326e-11 5.703278640854564e-10 -852.0834622790696 -1.2631591061856306e-10 7.307928510640936e-10 -578.5437855654411 -2.28023520589346e-10 9.021486790178623e-10 -395.6384309329947 -5.4165878735623956e-11 5.57605401596384e-10 -1029.4403314639787 -4.671994397898344e-11 4.987097652425088e-10 -1067.4451267896404 -5.0349999994343596e-11 4.55103066622809e-10 -903.8789804844804 +r_0573 inositol-1,4,5,6- tetrakisphosphate 3-kinase, nucleus 2.250000000105364e-12 5.683942750503174e-10 25261.967778831127 -9.157020128489626e-11 7.589341213747242e-10 -828.8003201101449 -5.6294146205035885e-11 1.028763745343839e-09 -1827.479080323647 -7.931856163940156e-11 6.14863629961712e-10 -775.1825263259415 -5.985268054177029e-11 6.718044370514034e-10 -1122.4299913895434 2.9609694095204656e-11 6.024633643230095e-10 2034.682838620004 -1.3749054083690418e-10 6.982536498889811e-10 -507.85577366902095 -1.6167977439840522e-10 7.841510915841462e-10 -485.0025889149688 -5.5454158342123545e-11 5.291265075839093e-10 -954.1692154436316 +r_0574 inositol-1,4,5-triphosphate 6-kinase, nucleus 2.250000000105364e-12 5.683942750503174e-10 25261.967778831127 -9.157020128489626e-11 7.589341213747242e-10 -828.8003201101449 -5.6294146205035885e-11 1.028763745343839e-09 -1827.479080323647 -7.931856163940156e-11 6.14863629961712e-10 -775.1825263259415 -5.985268054177029e-11 6.718044370514034e-10 -1122.4299913895434 2.9609694095204656e-11 6.024633643230095e-10 2034.682838620004 -1.3749054083690418e-10 6.982536498889811e-10 -507.85577366902095 -1.6167977439840522e-10 7.841510915841462e-10 -485.0025889149688 -5.5454158342123545e-11 5.291265075839093e-10 -954.1692154436316 +r_0575 inositol-1,4,5-trisphosphate 3-kinase, nucleus -1.2963397093551434e-10 1.0329030530514794e-09 -796.7842422765025 -5.780000000000001e-11 5.937420870488953e-10 -1027.2354447212722 -9.553745767944604e-11 6.312301520530195e-10 -660.714831004785 -6.693333333333326e-11 5.703278640854564e-10 -852.0834622790696 -1.2631591061856306e-10 7.307928510640936e-10 -578.5437855654411 -2.28023520589346e-10 9.021486790178623e-10 -395.6384309329947 -5.4165878735623956e-11 5.57605401596384e-10 -1029.4403314639787 -4.671994397898344e-11 4.987097652425088e-10 -1067.4451267896404 -5.0349999994343596e-11 4.55103066622809e-10 -903.8789804844804 +r_0596 IPS phospholipase C 8.020556543408265e-11 2.983151728606315e-09 3719.3824548971393 -3.235608810169873e-10 4.4451116684161245e-09 -1373.8099780309194 -2.6312449940687932e-11 3.41979891486412e-09 -12996.885210510009 -3.607141469471623e-10 3.751639507883215e-09 -1040.0588775445942 -2.390725486682472e-10 3.763687847514653e-09 -1574.2869135248957 5.1121514817001485e-11 3.396901667969753e-09 6644.7594131933765 -6.21785955254921e-11 3.849529251841197e-09 -6191.084277969836 3.762475517298639e-11 3.2352158563871444e-09 8598.636300788336 -8.843074206905605e-10 5.16492212352692e-09 -584.0640938525206 +r_0597 IPS phospholipase C -3.0811926996284224e-10 4.678135358951216e-09 -1518.28717480584 6.38871877503134e-10 3.6701294751415305e-09 574.4703444273185 1.8998423610955828e-10 3.884469576354766e-09 2044.627310086247 3.50983655846473e-10 3.141524990273829e-09 895.0630429492115 2.9097249792729663e-10 3.613821702119938e-09 1241.9805060143176 -1.3781847049889053e-11 3.609736949790776e-09 -26191.96785977853 5.668281513514623e-11 3.482780785616203e-09 6144.332770544951 -3.3352030269153717e-11 3.40951672770965e-09 -10222.81612302028 4.2798490177254524e-10 3.298889239236469e-09 770.7957046086826 +r_0598 IPS phospholipase C 1.4577574967946054e-10 2.727248951942834e-09 1870.8522905487737 -4.7170410553068636e-11 2.8365842421222957e-09 -6013.482199674778 6.808364349938313e-11 2.551558626511111e-09 3747.682255774442 -1.3666538511194964e-11 2.91000647560527e-09 -21292.9299780009 1.7013398208091827e-10 2.673102888443508e-09 1571.175173677026 -1.1386790924228076e-11 2.786387925904407e-09 -24470.352924244104 -5.085236569915738e-11 2.7012495292289e-09 -5311.944669810434 6.441198577409198e-11 2.71689829915564e-09 4218.001147619393 1.1136128340658551e-10 2.4242939435789023e-09 2176.963006728008 +r_0599 IPS phospholipase C 2.6522864617157072e-11 3.035590795157992e-09 11445.184518999256 8.078083487665473e-11 3.0714302567281673e-09 3802.176916613913 1.8439682575213608e-11 3.357979591242204e-09 18210.61494711389 3.212119026239895e-11 3.026071646295277e-09 9420.795498470665 7.505783467846666e-11 2.956765036258645e-09 3939.315660949798 -3.6484176613108835e-11 2.989938409361881e-09 -8195.164827394217 1.1359811208829764e-10 2.830199812456524e-09 2491.414479015869 1.706768937632962e-10 2.7174953269230356e-09 1592.1870072769211 1.6210690885761687e-10 2.409889096494069e-09 1486.6048051108935 +r_0600 IPS phospholipase C 6.572942602873139e-11 3.4967786162471073e-09 5319.95915302624 -6.802181518972475e-11 3.843754867791535e-09 -5650.767855974777 7.558111335670453e-11 3.379031743681309e-09 4470.735602602192 -3.9267470754214627e-11 3.267372034159553e-09 -8320.811020936108 -2.1367437297382998e-10 3.632711347544244e-09 -1700.11559972574 5.204354080665716e-12 2.978286990776138e-09 57226.83246784718 1.3816709214089424e-10 3.435446048965076e-09 2486.4430420680933 -5.71288042221563e-12 3.195780940668334e-09 -55939.9235496148 2.2052578665690335e-11 3.6901876776196675e-09 16733.588092175836 +r_0601 IPS phospholipase C 6.713794538737391e-11 3.420658450561158e-09 5094.970408797249 2.8963063778504076e-10 3.687222427355426e-09 1273.0774808748042 -2.2955293217796784e-10 4.124918490931517e-09 -1796.9356574080043 2.864328487592219e-10 3.063429623752728e-09 1069.5105805856351 1.2530204292542103e-10 3.337704367022762e-09 2663.7270144185454 2.5788151865856228e-11 3.253761669483074e-09 12617.273569693403 2.1124178068500595e-10 2.910524385789953e-09 1377.816630948588 1.8472566601263726e-10 3.4326547800776147e-09 1858.2446360446645 2.593939500081344e-10 2.7633344971822444e-09 1065.3041434064244 +r_0602 IPS phospholipase C 9.233622882463959e-11 2.975220774629898e-09 3222.1597226807808 -9.271402578650004e-11 3.1688321709638247e-09 -3417.856299607728 -7.516592090786029e-11 2.8383329450664357e-09 -3776.09016264926 -6.637552748911226e-11 2.888729009573485e-09 -4352.099514459347 1.3236917343762395e-10 2.7451595016565982e-09 2073.8661656372683 1.253181432697775e-10 3.2848639791001562e-09 2621.219795787028 -7.332711720047842e-11 2.9464349853371103e-09 -4018.206494169781 5.059713827815223e-11 2.7015891800908592e-09 5339.411026052833 -3.073443770598666e-11 2.718412044815706e-09 -8844.8406664235 +r_0603 IPS phospholipase C 6.220664735712691e-11 3.2248023210474223e-09 5184.015628641594 1.9782092165585863e-11 3.51982559766155e-09 17792.989579660607 2.1267651437899173e-11 3.019611334036651e-09 14198.141919213856 9.644212132590879e-12 3.2343404456940323e-09 33536.5958486558 5.883561419322095e-11 3.283379076419863e-09 5580.5979447023 -3.0303672822220076e-11 3.512440821253447e-09 -11590.808948669615 -1.6631310047493972e-11 3.027436580226958e-09 -18203.23577385978 1.5694884334654848e-10 2.5283987419471487e-09 1610.9699746970143 4.648134247501495e-11 2.9525953370422563e-09 6352.216136247271 +r_0604 IPS phospholipase C -3.112529480768705e-10 3.9195987501142154e-09 -1259.2969076540878 -1.7636643473095736e-10 3.3966232559213038e-09 -1925.88984468772 -2.1992160913829275e-10 3.5213146202145947e-09 -1601.1680862158005 -9.562931363331143e-11 3.2667657481562717e-09 -3416.0715203735704 -3.3634993998956685e-10 3.584781043804246e-09 -1065.7891135391435 -2.1164465947698518e-10 3.435614986302997e-09 -1623.2939658355028 -3.9301633362791774e-10 3.566673966673294e-09 -907.512910150444 -1.803486279881452e-10 2.8546805658985703e-09 -1582.867914074853 -1.7565325480446684e-10 3.052512281914936e-09 -1737.8057043764563 +r_0605 IPS phospholipase C 7.945781417347003e-11 3.920502010188265e-09 4934.0672795618775 -3.212318750494555e-10 4.8258667975372494e-09 -1502.3001054282922 1.7759658520352632e-10 3.766657836136093e-09 2120.9066783685566 -1.0352890966934856e-10 3.422741077387225e-09 -3306.0727562173715 -6.35742660936205e-11 4.179901957016574e-09 -6574.833205091479 9.616898281618831e-11 3.4113988479420876e-09 3547.296381893144 7.631591362964151e-11 3.8768913391137835e-09 5080.056248724484 -4.455717436660023e-10 3.806691880530946e-09 -854.338708556981 6.131414803357797e-11 4.5547612346262305e-09 7428.564826721343 +r_0606 IPS phospholipase C 5.720855810523805e-11 4.2583795420681694e-09 7443.6057875023935 -7.43926204193672e-11 4.010670499298734e-09 -5391.220898914062 -5.899542001175205e-10 5.1452567793053e-09 -872.14512216039 3.9666176558438116e-11 3.9900152496038065e-09 10058.986259302112 -2.5590631216529187e-10 4.3538113271359155e-09 -1701.3301822440994 7.634453142863927e-11 3.543204283399602e-09 4641.071491428963 3.01559096666865e-12 4.280417072207134e-09 141942.89343344694 1.3182995273717558e-10 3.925826370255147e-09 2977.947187830613 -8.548404002708916e-11 3.898312056477504e-09 -4560.28055674739 +r_0607 IPS phospholipase C -1.6067756089864203e-11 4.0867869670698716e-09 -25434.70876837545 9.376713036255332e-10 4.321556682409766e-09 460.8818320130245 2.3359119398052545e-10 4.145702903503796e-09 1774.7684888538329 4.444910216862403e-10 4.047005670649355e-09 910.4808586001266 5.513050232143223e-10 4.2480402596230774e-09 770.5426362443338 5.5584979917817605e-11 3.8304518339154295e-09 6891.1634754186325 1.8261956584018303e-10 3.979245600450088e-09 2178.9809772806434 5.113583828737667e-10 4.070238755290197e-09 795.965978384082 5.859192607707977e-10 3.5912175682743342e-09 612.9202108068541 +r_0608 IPS phospholipase C -2.505565332028938e-10 4.110396013760739e-09 -1640.5064203343893 -3.4205348587362886e-10 4.44906145208184e-09 -1300.6917443681714 -2.7829007718583744e-10 3.819673857268862e-09 -1372.5512227725417 -2.0927048282287247e-10 4.0015063853251904e-09 -1912.1217342018 8.058986463250362e-11 3.470404324579442e-09 4306.254068554117 -4.046785208010178e-11 3.3258626072286486e-09 -8218.530107912473 -3.9422329913134286e-11 3.449246124643639e-09 -8749.473032780994 -1.0369463761070206e-10 3.6681746204996494e-09 -3537.477641101344 8.33001159845256e-11 3.1699431685226887e-09 3805.448685223391 +r_0609 IPS phospholipase C -5.48879454946988e-11 3.917895643552214e-09 -7137.9892401522175 -2.527993913449117e-10 4.0634310088891325e-09 -1607.3737311119992 3.096852411926385e-11 3.483467742503305e-09 11248.413805863056 9.2577370731836e-11 3.427442650602807e-09 3702.246697555173 1.9935982882559966e-10 3.56558431968211e-09 1788.516944806012 -9.013566446474214e-11 3.869274337949174e-09 -4292.722931512528 -2.0466982984297693e-11 3.410330682435928e-09 -16662.595972510167 1.4043702754132388e-10 3.439340383194318e-09 2449.026758404072 3.275678485258082e-11 3.369608421851996e-09 10286.749560485372 +r_0610 IPS phospholipase C 8.329210996235276e-11 3.729768406952279e-09 4477.9372363578 -1.3560873091868627e-10 4.198126178458175e-09 -3095.7639305506486 1.8399964703541958e-10 3.720452817898164e-09 2021.9891058714825 -6.938344179856319e-11 4.56621515233052e-09 -6581.130935515334 -5.855684825407977e-10 5.1845365944556814e-09 -885.3851853432811 -1.6857899426961192e-10 4.543992399567719e-09 -2695.4677356186003 1.3131021155944002e-10 3.5479401423696763e-09 2701.9529557026376 2.2379471621410892e-10 3.762964834962921e-09 1681.4359599816537 1.0495704956590123e-10 4.135253498849657e-09 3939.948308334623 +r_0611 IPS phospholipase C 8.440405180486446e-11 3.793602373738393e-09 4494.573770592085 1.1787542719075688e-10 4.6609233870782865e-09 3954.1094341363855 1.8097743248264368e-10 4.12070690835013e-09 2276.9175426031743 2.6677059693294404e-10 3.921414884922611e-09 1469.957682745788 1.6798171684026656e-10 4.074011415014527e-09 2425.2707328193906 1.386054492478775e-10 3.7553455985882555e-09 2709.378035976289 1.0373130565876028e-10 3.7006565268430432e-09 3567.540679587037 2.4618034216436557e-10 3.819997955985839e-09 1551.7071437959762 2.2000510678027358e-10 3.687589610104664e-09 1676.1381879137848 +r_0612 IPS phospholipase C 6.240312039575337e-12 4.236643860245776e-09 67891.53865027055 -3.7434093885316376e-11 3.572867063864036e-09 -9544.419786972598 -1.2721326665993178e-10 4.100296081912421e-09 -3223.1670403318767 -7.038466891830673e-11 3.685154811012859e-09 -5235.735093518877 1.1244808937990348e-10 3.678960393867572e-09 3271.6966683518144 1.298443342380304e-10 3.299426098466484e-09 2541.062817895452 -5.235834534012887e-11 3.558703024946093e-09 -6796.82102600482 -1.0311712292335174e-10 3.754222113681289e-09 -3640.7359003526985 -3.891769071327097e-11 3.653508667246937e-09 -9387.783808048733 +r_0613 IPS phospholipase C -2.888479916119817e-10 4.314352755148749e-09 -1493.6412509124698 -2.846212908727224e-11 3.904069889597473e-09 -13716.717669386522 -1.2938735700336867e-11 3.7183952534282604e-09 -28738.47445026217 1.168571231462249e-10 3.757435978942542e-09 3215.4103042916868 1.7784257758932463e-10 3.843332398456258e-09 2161.086760298374 1.923739480612021e-11 3.81393480417437e-09 19825.630458865453 -1.6053959932012252e-10 4.139456465953332e-09 -2578.464430884175 2.52183144975893e-10 3.557452678129791e-09 1410.6623495673584 -4.064021276713827e-11 3.3410998257751103e-09 -8221.167160022174 +r_0614 IPS phospholipase C -2.533436651964986e-10 4.926356452143325e-09 -1944.5350837260287 -3.1397391759789184e-10 4.613564605498616e-09 -1469.4101474400925 -8.895942133827513e-11 4.4221706650650216e-09 -4970.997561067054 -6.392196919897426e-10 4.6746590857845804e-09 -731.3071146530937 -4.261447056707488e-10 4.330061370335351e-09 -1016.101177068448 -4.5883441838105823e-10 4.471888120828815e-09 -974.6191527234008 -6.92345454797482e-10 4.881227330415745e-09 -705.0277136351755 -3.0564736721853637e-10 3.9112291950521825e-09 -1279.6541421721693 -4.978968597738165e-10 4.743604292859442e-09 -952.7283010008044 +r_0615 IPS phospholipase C 6.325588596831018e-10 5.870320866779726e-09 928.0276099082114 1.2917768995189726e-10 5.707392452820931e-09 4418.249354781176 4.678189232817983e-10 6.0482124783857e-09 1292.853319390515 2.789599925992953e-11 5.592524162077123e-09 20047.764233025187 -2.1907587928404903e-11 6.092608595630911e-09 -27810.49477259597 3.384002395027367e-10 5.468337991002339e-09 1615.9379789558675 5.44456038363336e-10 5.8939775025699906e-09 1082.5442436615451 -9.93324439723208e-10 6.473147697178444e-09 -651.6649986969213 -3.6399951449536647e-10 6.8762754886903995e-09 -1889.0891923917468 +r_0616 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0617 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0618 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0619 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0620 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0621 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0622 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0623 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0624 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0625 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0626 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0627 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0628 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0629 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0630 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0631 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0632 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0633 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0634 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0635 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0636 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0637 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0638 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0639 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0640 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0641 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0642 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0643 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0644 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0645 IPS phospholipase C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0646 IPS phospholipase C 0.0001630318810186 0.0020747083768584 1272.5783226541323 0.0002927873509762 0.003791706786434 1295.0377718815037 0.0002315136778375 0.0031173735561142 1346.5180913853908 0.0002938883448406 0.0042418622163347 1443.3584355430685 0.000780452906911 0.0098291854875659 1259.420703097747 0.0005039135401758 0.0070888197951199 1406.75318878044 0.0008195063196659 0.0123137277956074 1502.5787477303525 0.0017466366232343 0.0221509429077513 1268.2055679522794 0.0016924988820525 0.0213409267098703 1260.912307604601 +r_0647 IPS phospholipase C 0.0001874376926947 0.0022491547798998 1199.947965408708 0.0002383711334472 0.0034192907397435 1434.4399383829611 0.0001545152790783 0.0025493819478158 1649.9222361845732 0.0004230356422087 0.00503755744464 1190.8115870186602 0.0007327893733117 0.0094788577936519 1293.5310116212054 0.0006523181230012 0.0081295785933932 1246.2598089394282 0.0009740566518443 0.0134178146255621 1377.5189153686033 0.0017295329274589 0.0217146045153593 1255.5184218008862 0.0015585641101214 0.0204599088833889 1312.7409229123243 +r_0648 IPS phospholipase C 0.0001202081333907 0.0018075982334733 1503.723735229746 0.0001759364562383 0.0029510674090309 1677.3484428001084 0.0001622550934567 0.0026274325996926 1619.3221079941995 0.0002149551830777 0.003611180495016 1679.9690257808772 0.0004722194605249 0.0076036483580981 1610.1937750819775 0.0005134517686218 0.0072446041351047 1410.9609855954964 0.0007363768198014 0.0116920924463573 1587.7865967467485 0.0011713145567044 0.0181504755833058 1549.5816627066724 0.000886545150895 0.015498402997947 1748.179772039829 +r_0649 IPS phospholipase C 6.695821585821268e-05 0.0013575085262339 2027.3965021836048 0.0002278331974365 0.0033508210365026 1470.7343241477918 0.0001972529715154 0.0028572982613491 1448.545103983237 0.0002946688058258 0.0042622820097452 1446.4652944174804 0.0005031680931695 0.0079326995215415 1576.550586022406 0.0005144213373993 0.0072576080898461 1410.8295209013277 0.00079360165938 0.012208636301465 1538.3834140420774 0.0013320709921132 0.0194364449273845 1459.1147951168996 0.0015672414435809 0.0206047927347832 1314.7171942890643 +r_0650 IPS phospholipase C 0.0001152038689364 0.0017748811193325 1540.6436743121287 0.0001827472261931 0.0030133179275912 1648.8994062248833 0.0001533919382045 0.0025377442784509 1654.418288310702 0.0002378706034712 0.003810702911662 1602.0066607862905 0.0006811391347235 0.0092159691544343 1353.0229999448022 0.0003971435930939 0.006210350980353 1563.7545432802374 0.0007919162821742 0.0121773209934838 1537.7030713461388 0.0010252879822997 0.0170460396962813 1662.5611526282487 0.0011875375235318 0.0179121726354397 1508.3458232265357 +r_0651 IPS phospholipase C 0.0001380623986727 0.0019476825871037 1410.7263134837938 0.0003661871844822 0.0042504911903303 1160.7427486409854 0.0002926298808747 0.003440549946541 1175.7343222286486 0.0003056298809264 0.0043619088540761 1427.1866483912906 0.0008690325217096 0.0102435666323119 1178.7322541347569 0.000506436443417 0.0070475384005803 1391.593849966548 0.0012421481492471 0.0151260081720289 1217.7297998790957 0.0016362136754639 0.0213833765767209 1306.8816681695505 0.0014047533730844 0.0194691245358192 1385.946096222577 +r_0652 IPS phospholipase C 0.0001425043755035 0.0019332762878117 1356.6434581258131 0.0001847471091717 0.0029831548934277 1614.7234491528138 0.0002030285591516 0.0028968150098536 1426.8017376261507 0.0003436219564938 0.004630295631608 1347.4970222664365 0.0005799468787098 0.0085187937452228 1468.8920758007305 0.0004294487569577 0.0065924041374883 1535.0851599128432 0.0010237187302529 0.01382165051992 1350.1414120365466 0.0012034583306048 0.0185162484345218 1538.5865853133237 0.0009369689624292 0.0160431988107286 1712.2444236715928 +r_0653 IPS phospholipase C 0.0001113798268811 0.0017379859254081 1560.4135632778732 0.0002189247326579 0.0032511698739392 1485.0628498966514 0.0002086497213229 0.0029493343253651 1413.5337956191474 0.000225086706816 0.0037339059700481 1658.8744945739973 0.0005334470210859 0.0080312370169893 1505.536013799387 0.0004723268452726 0.0069189308949783 1464.8608192033305 0.0009096021931077 0.012913166539399 1419.649890605432 0.0013297217136472 0.0192736674118076 1449.451205767122 0.0013300735275623 0.0190329122794935 1430.9669266462042 +r_0654 IPS phospholipase C 0.0001055046914975 0.00168855171051 1600.4517775869272 0.0003006809335163 0.0038337301487169 1275.0160457078237 0.0002040194397233 0.0029095728783288 1426.125315447177 0.0003046980293153 0.0043307138416567 1421.3133742241232 0.0007131553984439 0.0093162971962504 1306.3488289618929 0.0006736987668506 0.0081876022326101 1215.3209469100257 0.0010716990373946 0.0139921626080429 1305.6055963303295 0.0014575619229983 0.0202239882635294 1387.521719964159 0.001607017461336 0.0207473064646146 1291.0442458643563 +r_0655 IPS phospholipase C 0.0001595685589846 0.0020768142081138 1301.5184327842846 0.00028009281641 0.0037213104703721 1328.5990401567983 0.0002187428703392 0.003015374226757 1378.5017185154825 0.0003842467722463 0.004820466927946 1254.5237269697504 0.0006259284694508 0.0087778027572488 1402.3651560298272 0.0006131383991704 0.0078702230121772 1283.59649678211 0.0013172456777205 0.0155736750356035 1182.2908436149585 0.0018592220460315 0.0227001282969892 1220.9476724655729 0.0018384672958292 0.0220954901114685 1201.842978746173 +r_0656 isoamyl acetate-hydrolyzing esterase 3.5434461736278816e-05 0.0012524214311753 3534.472854410737 8.019545802322602e-05 0.0025351366716926 3161.197322370151 6.812440256925614e-05 0.0021534207219265 3161.0122668412973 4.0254646721232486e-05 0.002012527344525 4999.490763046473 0.0001205528845162 0.0049205663938703 4081.666244335308 0.0001969949012847 0.005683908359529 2885.307346769117 0.0002416065936148 0.008539519521095 3534.472877304157 0.0003666988295092 0.0129608708125673 3534.4729160749102 0.0002641996924484 0.0107837494903318 4081.6661784858575 +r_0657 isobutyl acetate-hydrolyzing esterase 2.631499763346532e-05 0.0010741636691275 4081.9447681100014 3.2251630643309296e-05 0.0016124202436904 4999.499905983658 3.675569605779532e-05 0.0015189756650865 4132.6265803757415 0.0001003554935584 0.0031722991950057 3161.0618238422803 0.0001607371690587 0.0056812123601161 3534.473322745408 9.849751904273508e-05 0.0040203400808424 4081.666340345264 0.0002411782821323 0.0085244213228692 3534.489609720721 0.0002750241115369 0.0112255662477988 4081.666216487002 0.0002641995796707 0.0107837449116271 4081.66618776067 +r_0658 isocitrate dehydrogenase (NAD+) 0.2935851269145126 0.2039165042927898 69.45736878291083 0.6028683332763447 0.4031518493110943 66.87228820265408 0.6410873738221198 0.5434178918467653 84.76502798783017 1.4014670330075096 0.910327574917364 64.95533276753761 1.6483403291905931 1.660256418927592 100.72291440826726 1.773424407220941 1.3121059005914182 73.9871344529178 2.3331633169581925 1.933843431368775 82.885043550658 3.11572311831835 2.7854431865609186 89.3995737356889 2.117527554380613 2.285374285437627 107.92654294910038 +r_0659 isocitrate dehydrogenase (NADP) -0.0309868933781746 0.2440244305184473 -787.5085364005021 -0.1731054581630066 0.4805335487209161 -277.5958388720572 -0.0540341907894345 0.6361575086303206 -1177.3240226902974 -0.4553963285256144 1.0841102584117344 -238.05862948470323 -0.3818115097489777 1.922264749242371 -503.4590891474606 -0.1004479485195198 1.5700095587556109 -1563.0080871691612 -0.2742447657618962 2.258860478993748 -823.6658492709125 -0.5729266866509723 3.2901613581722446 -574.2726660901056 -0.3518126242883961 2.553647015835287 -725.854287065592 +r_0661 isocitrate dehydrogenase (NADP+), peroxisomal 4.1468842661388153e-05 0.0004613084255072 1112.421750647813 7.524246414415254e-05 0.0008107644139629 1077.535701661243 6.658079450419674e-05 0.0007164160386695 1076.0100476487669 0.0001016876279765 0.0010901555562186 1072.0631190939985 0.0002184397901925 0.0022468108588711 1028.5721556914298 0.0001820772748804 0.0018554821016152 1019.062979074714 0.0004249476064617 0.0038478219311734 905.481492933178 0.0004706324047729 0.0049384599676355 1049.324253398613 0.0004876144501209 0.0049513175021185 1015.4164834308284 +r_0662 isocitrate lyase 0.0011075829498617 0.0062701713161234 566.1130226775488 0.074076742161075 0.0356879039523695 48.17693504226809 0.152741403543355 0.0707298907957665 46.30695355348766 0.2577757721973067 0.1835838524282011 71.2184278853338 0.6299721378376844 0.2444210004858551 38.79870010200856 0.0060352800292019 0.0293323670473164 486.0150134772667 0.5307772880555047 0.2430147882248706 45.78469985314405 0.4008888129125222 0.2319187556223196 57.851141800987726 1.4401119892600245 0.685521847710529 47.60198184745148 +r_0663 isoleucine transaminase -0.0019803927311196 0.0180885818912492 -913.3835732179576 -0.0020651390785364 0.0402114807130783 -1947.156059899665 -0.0147858060706485 0.0303813224416693 -205.4762675535132 -0.0258061805014966 0.0457589590876979 -177.31782928916613 -0.0234457503458871 0.0901956950117455 -384.69954546610495 -0.0356872512998289 0.0842512764808687 -236.0822798400073 -0.0373444376753061 0.1448960775918607 -387.9990879811064 -0.0456922324263932 0.1988423619175515 -435.1776031908083 -0.0483831199428346 0.1988274846142603 -410.9439094650732 +r_0664 isoleucine transaminase -0.0018989840477181 0.0180879120654034 -952.5046872899476 -0.0045297682238293 0.0402104943319793 -887.6943001288124 -0.0034250444320576 0.0303800671254192 -886.9977522355242 -0.0047671658835435 0.0457572172411046 -959.8410955041428 -0.0094775121295583 0.0901924391749884 -951.6467817930568 -0.0104072216328711 0.0842474106715028 -809.5091432030971 -0.0160350790073878 0.1448895922217034 -903.5789106804416 -0.0214861161658402 0.1988326577489664 -925.4006457671552 -0.0226985092267782 0.1988184971628946 -875.9099338926688 +r_0665 isoleucyl-tRNA synthetase 0.0038793772326378 2.8663013836082616e-05 0.7388560616105142 0.0065949076147663 4.068669855882671e-05 0.6169411451303319 0.0182108505610926 5.131009173875037e-05 0.2817556026096555 0.0305733468346405 8.277249047030917e-05 0.2707341493163757 0.0329232624337538 0.0001386219316568 0.4210455508040888 0.0460944734740529 0.0001342558776225 0.291262417170441 0.0533795166826447 0.00025220065578 0.4724671024644833 0.0671783486162485 0.000394362084187 0.5870374790541494 0.0710816291780967 0.0003578699115567 0.5034632938141061 +r_0666 isoleucyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0667 isopentenyl-diphosphate D-isomerase 0.0017387017218494 0.0004704778943728 27.05914927560996 0.002770078975102 0.0003279418182545 11.838717278538402 0.0064071542065942 0.0004960230598835 7.741706284718634 0.0095232241388507 0.000753042965135 7.9074371678695075 0.0135128835626083 0.0015599666154681 11.544291107375356 0.0159587963525963 0.0015250087834939 9.555913552627542 0.0179375591865093 0.0023267857602088 12.971585130483074 0.0211470142755956 0.0032761696180095 15.492350718230416 0.023903403965598 0.0031857967281831 13.327795207611985 +r_0668 itaconate-CoA ligase (ADP-forming) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0669 ketol-acid reductoisomerase (2-aceto-2-hydroxybutanoate) 0.0042211911330579 0.0030707206928651 72.7453601618999 0.0066940572265752 0.0011505808435696 17.188093926085486 0.0184809547492617 0.0028310934783083 15.318978465771313 0.0309042586543443 0.0033751935751223 10.921451353591523 0.0336361144822849 0.0079457980821438 23.622817927821654 0.0470225431466737 0.0089587810545294 19.052098110867927 0.0544810842792153 0.0121277819668934 22.260537078775084 0.0687090247361664 0.017115599801579 24.910264506446893 0.0726517220583299 0.0169596819908387 23.34381279664963 +r_0670 kynureninase 4.8484248275275696e-05 0.0007012901042174 1446.4287457562643 6.232396445698709e-05 0.0010845933038927 1740.2508222037827 5.469642904683071e-05 0.0008582503781231 1569.115924164527 8.534817515757606e-05 0.0013126025517411 1537.9386253047935 0.0001665397492539 0.0026833751732325 1611.252079610336 0.0001582268702969 0.0024779434650418 1566.0699477849244 0.0002131675431084 0.003668299800263 1720.85287786834 0.0004021038979561 0.0059034632198926 1468.1437434203096 0.0004229713058368 0.0062855008932482 1486.0348223415103 +r_0671 kynurenine 3-monooxygenase 0.0001378827306078 1.0101320085441572e-06 0.732602265773807 0.0002246330887973 1.3712590740263496e-06 0.6104439383209892 0.000521658306396 1.4691516407787686e-06 0.2816310260500817 0.0007754600284313 2.099279363171992e-06 0.270714064710545 0.0010934112804882 4.6029820656476095e-06 0.4209744446382616 0.0012959484111734 3.774678645619304e-06 0.2912676625917181 0.0014508701543442 6.853461558013463e-06 0.47236904953158 0.0017039072121787 1.0001094368091705e-05 0.5869506447656477 0.0019320197466961 9.725921543180266e-06 0.5034069429058465 +r_0672 L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase 2.6199999999999952e-11 4.502822568369249e-10 1718.63456807987 -1.6199999999999887e-10 8.140568393592225e-10 -502.5042218266842 3.5840000000001047e-10 7.411202951332462e-10 206.7857966331541 -6.460000000000022e-11 7.94577315698171e-10 -1229.9958447340064 4.239999999999988e-11 4.897450459596443e-10 1155.0590706595422 2.8599999999999945e-11 3.6139751193433765e-10 1263.627664106078 -2.439999999999996e-11 6.766802932285323e-10 -2773.2798902808745 -1.7999999999999832e-10 6.726741396097037e-10 -373.70785533872777 2.7599999999999942e-11 5.212413821980229e-10 1888.555732601536 +r_0673 L-4-hydroxyglutamate semialdehyde dehydrogenase -8.194000000000216e-10 5.564580569223683e-10 -67.9104292070239 -6.36000000000031e-10 5.656571343125625e-10 -88.93980099253692 -8.644000000002203e-10 5.682228571976572e-10 -65.73610101775942 -5.562000000000253e-10 6.700233923298931e-10 -120.46447183205008 -8.294000000000207e-10 5.996395196371785e-10 -72.29798886389719 -3.1340000000000447e-10 5.73451139367483e-10 -182.97738971521213 -4.896000000000195e-10 8.226950865546157e-10 -168.03412715575635 -3.4900000000001363e-10 1.2422188299668694e-09 -355.9366274976565 2.403999999999991e-10 1.6304415070469215e-09 678.2202608348284 +r_0674 L-alanine transaminase -3.716583016995875e-05 0.0010257666244375 -2759.972317978052 -0.0002180534477219 0.0052668577076036 -2415.397583770168 -6.811886994056263e-05 0.003405476630663 -4999.3146299028285 -0.0001195181111674 0.0052051055944263 -4355.076852857129 -0.0003013819132449 0.0123014156225489 -4081.670160661359 -0.0003283213967679 0.0116044568534747 -3534.480837286527 -0.0004608955016583 0.0155033196604109 -3363.738549113393 -0.001145933009446 0.036223112751906 -3161.0148632872924 -0.0007600097160249 0.027270860742281 -3588.225277554968 +r_0675 L-allo-threonine aldolase -4.4040000000001675e-10 4.96484782675042e-10 -112.73496427679908 -7.422000000000394e-10 4.42920303981572e-10 -59.67667798188473 -9.333999999999815e-10 2.509522572265152e-10 -26.885821429882164 -5.708000000000263e-10 4.950114819612311e-10 -86.72240398759777 -5.730000000000267e-10 4.95499852695032e-10 -86.47466888220056 -5.310000000000235e-10 4.990879859940025e-10 -93.99020451864035 -3.9480000000001326e-10 4.892656090174405e-10 -123.9274592242716 -1.933999999999982e-10 3.9500334875680975e-10 -204.24164878842475 -6.634000000000333e-10 4.730171128382314e-10 -71.30194646340179 +r_0676 L-allo-threonine dehydrogenase 4.4040000000001675e-10 4.96484782675042e-10 112.73496427679908 7.422000000000394e-10 4.42920303981572e-10 59.67667798188473 9.333999999999815e-10 2.509522572265152e-10 26.885821429882164 5.708000000000263e-10 4.950114819612311e-10 86.72240398759777 5.730000000000267e-10 4.95499852695032e-10 86.47466888220056 5.310000000000235e-10 4.990879859940025e-10 93.99020451864035 3.9480000000001326e-10 4.892656090174405e-10 123.9274592242716 1.933999999999982e-10 3.9500334875680975e-10 204.24164878842475 6.634000000000333e-10 4.730171128382314e-10 71.30194646340179 +r_0678 L-aminoadipate-semialdehyde dehydrogenase (NADPH) 0.004813227326796 3.556267182060622e-05 0.7388529443149939 0.0081824453907497 5.0480787401053e-05 0.616940107637278 0.022594599529601 6.366143382880475e-05 0.2817550881811481 0.0379330186829625 0.000102697486902 0.2707337577333328 0.0408486101048924 0.0001719910494753 0.4210450466582642 0.0571904195277281 0.0001665740336442 0.2912621292513366 0.0662291318641015 0.0003129107419644 0.472466923779927 0.0833496440291107 0.0004892934691728 0.5870372631728625 0.0881925296371844 0.0004440169180408 0.5034631843166931 +r_0679 L-asparaginase 1.1072596624255234e-05 0.0005536063474755 4999.78791120067 3.02345132014208e-05 0.001234079940952 4081.6927751761455 3.343867594243418e-05 0.0011825334770294 3536.424346063337 2.5159092142594984e-05 0.001257830023773 4999.504817757179 0.000164372940299 0.0044494587734074 2706.9289904485777 0.0001231213306572 0.0035524421991108 2885.3182305197547 7.550149940759324e-05 0.0037747256950209 4999.537392818033 0.0004007287085735 0.0107035397741631 2671.0189575044683 0.0003301605334111 0.0095261641168641 2885.312795700218 +r_0680 L-asparaginase 3.139999999999994e-11 2.771811788004033e-10 882.7426076445983 2.600000000000001e-12 5.40972984865277e-10 20806.65326404911 3.5480000000001355e-10 7.015806461702126e-10 197.7397537120027 1.819999999999998e-11 6.59360077000591e-10 3622.857565937317 8.70000000000034e-11 9.37020064523834e-10 1077.0345569239057 4.5199999999999874e-11 3.730747873542049e-10 825.3866976862962 -8.319999999999733e-11 8.282602024681706e-10 -995.5050510435065 1.4663451827445318e-10 7.615906247208811e-10 519.3801798396647 -1.4100000000000238e-10 9.585941688514894e-10 -679.8540204620376 +r_0681 L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase -1.001799999999986e-09 6.208654079355583e-10 -61.97498581908234 -2.9099999999999036e-10 1.3689023992804224e-09 -470.41319562902686 -1.4605999999995572e-09 6.597989898005472e-10 -45.17314732306911 -2.3640000000000117e-10 1.2102925272843603e-09 -511.9680741473581 -8.528000000000204e-10 9.642189085579815e-10 -113.06506901477005 -1.405800000000042e-09 8.861621841871472e-10 -63.03614910991043 3.3900000000001475e-10 1.0691621119008492e-09 315.3870536580539 7.216000000000381e-10 7.84229840855739e-10 108.6793016706898 2.199999999999999e-11 9.304241709175503e-10 4229.200776897958 +r_0682 L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase 2.8800000000000526e-10 4.5331787899870444e-10 157.4020413189917 9.729999999999678e-10 1.657603550281474e-10 17.03600771101263 7.614000000000406e-10 4.2673933647166247e-10 56.046668830002574 9.575999999999734e-10 2.0545238410985486e-10 21.45492732976824 3.4800000000000976e-10 4.763836566021588e-10 136.89185534544407 7.678000000000393e-10 4.2275158637284126e-10 55.06011804803591 8.08400000000025e-10 3.9461447530068126e-10 48.81425968588187 7.332000000000387e-10 4.423312010002092e-10 60.32885992910335 6.688000000000337e-10 4.711167054881907e-10 70.44209113160387 +r_0683 L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase 7.598000000000405e-10 4.3421385092332436e-10 57.14844050056609 -6.76000000000011e-10 1.371349743874285e-09 -202.86238814708025 7.143999999998266e-10 4.665577940994368e-10 65.30764195122478 -4.1899999999995616e-10 1.3029883175651383e-09 -310.9757321158173 5.426000000000275e-10 8.835957154024946e-10 162.84476878039993 7.333999999998291e-10 5.926168061535956e-10 80.80403683579684 -4.440000000006207e-10 1.3629510362091928e-09 -306.9709541007404 -5.200000000001077e-10 1.2399627016568034e-09 -238.45436570318208 2.21399999999895e-10 5.032223032985998e-10 227.29101323344105 +r_0687 L-hydroxyproline reductase (NADP) 0.000390870274707 0.0089073431385694 2278.8489468135804 0.0004031452092375 0.0127434712241912 3161.012690264343 0.000401903223854 0.0116045579309335 2887.4010563172405 0.0007044549424921 0.0188160530967121 2671.008741899982 0.0015801256817717 0.0394963790237537 2499.571994771227 0.0006566495332658 0.02320910124601 3534.473120018519 0.0021025820140802 0.0561651613864891 2671.2471147556325 0.0027502415891088 0.0793529234642298 2885.3073773036103 0.0026252155024108 0.0757532828828036 2885.602451045888 +r_0688 L-lactaldehyde:NADP+ 1-oxidoreductase 0.0001082769899574 0.0020758651556249 1917.18033207236 0.0002133738156113 0.0041039542045145 1923.36355459368 0.0001147228965593 0.0025884659239368 2256.2766470918023 0.0002384576891352 0.0045927411173867 1926.019300967564 0.0005181969274115 0.0096628799058804 1864.7119260525128 0.0002797218132573 0.0063900040220717 2284.413913831537 0.0007449925699094 0.0147272834705145 1976.836288757234 0.0009265919079858 0.0192161199800089 2073.849319683728 0.0012346262115666 0.0222973968089335 1806.003841489749 +r_0689 L-serine deaminase 0.0001011397087014 0.0023493312635492 2322.8574550128046 0.0001603509431275 0.0040059658944917 2498.2490382397727 0.0001532800051309 0.0036099495976042 2355.1340532121017 0.0001006364014657 0.0035569660393726 3534.4726039148463 0.0003013668483398 0.0086953584441321 2885.306891595096 0.0004103657813178 0.0091677940458306 2234.054217773384 0.0004533461808925 0.0126276214454124 2785.425791070108 0.0004583737559994 0.0162010919535407 3534.4719765242694 0.0006604989266313 0.0190574237244227 2885.307296655254 +r_0690 L-serine dehydrogenase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0691 L-sorbitol dehydrogenase (L-sorbose-producing) -2.9700000000000595e-10 5.4849901570927e-10 -184.67980326911083 9.939999999999606e-10 1.037600753211294e-10 10.438639368323294 9.733999999999675e-10 2.2249121436157806e-10 22.85712085078955 9.959999999999598e-10 8.237327886768806e-11 8.270409524868613 9.715999999999684e-10 2.2091446453351542e-10 22.73718243449183 -1.5579999999999906e-10 5.38501956237283e-10 -345.6366856465252 9.715999999999684e-10 2.0591726587170536e-10 21.193625552872795 7.994000000000282e-10 5.134319453175037e-10 64.2271635373387 9.763999999999666e-10 2.045761723223412e-10 20.952086472997564 +r_0692 L-threonine deaminase 5.017229563828295e-05 0.0007641297898725 1523.011415267075 3.026771154514085e-05 0.0006043124199187 1996.55801205028 0.0001065798748475 0.001277509717318 1198.6406618940664 0.0003123536961243 0.002958770911962 947.2501682146186 0.0003911034802025 0.003483416029155 890.6635214167295 0.0004343894083789 0.0047499261323183 1093.4719034802472 0.0004794107474637 0.0046428163695352 968.4422792141096 0.000863661392023 0.0093821553951071 1086.323353314438 0.0007567534779391 0.007967471284401 1052.848981427656 +r_0693 L-threonine deaminase 3.3470938629015885e-05 0.0009048733215343 2703.4596536527606 3.530273893518234e-05 0.0009163611250559 2595.7224643062505 6.886159247503495e-05 0.0014432787094946 2095.912478378868 0.0001538184268879 0.0026323302121961 1711.3230615172615 9.736397921221498e-05 0.0027827679934667 2858.1083229984383 0.0001489716089114 0.0033592484611988 2254.9588379593933 0.0002574233355447 0.0058528770704473 2273.638890608193 0.000287292725469 0.0071944325299565 2504.216742073569 0.0002253019875587 0.0061200836126623 2716.3913106034734 +r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.0001863672338793 0.0007012758866742 376.2871144656452 0.0002869573137862 0.0010845775050998 377.95778430926174 0.0005763548767434 0.000858232028181 148.9068736661384 0.0008608083823484 0.0013125937061102 152.48384344600038 0.0012599511849628 0.0026833173616335 212.96994626919684 0.0014541754857708 0.0024778916984809 170.3983957044517 0.0016640384549398 0.0036682171006966 220.4406448545308 0.0021060111547125 0.0059033228332455 280.3082414846548 0.0023549918449674 0.0062853653062885 266.89541705719 +r_0695 L-tyrosine N-formyltransferase 1.6456788356828003e-05 0.000359279864442 2183.171203589948 7.778132908682509e-06 0.0002749304084874 3534.6581463086777 2.4189111755491148e-05 0.0006460934639539 2671.009462789576 3.80516301251899e-05 0.0009540499146447 2507.251099377032 4.04801027985284e-05 0.0014307580649367 3534.472409958272 3.691561793485231e-05 0.0010651274284966 2885.302991206508 7.632152542667071e-05 0.0024125326181463 3161.012053492428 0.000206551486734 0.0048646295196939 2355.165579591457 0.0001551832410595 0.0041449566284839 2671.007900197501 +r_0696 lactaldehyde dehydrogenase 0.0001082769899574 0.0020758651556249 1917.18033207236 0.0002133738156113 0.0041039542045145 1923.36355459368 0.0001147228965593 0.0025884659239368 2256.2766470918023 0.0002384576891352 0.0045927411173867 1926.019300967564 0.0005181969274115 0.0096628799058804 1864.7119260525128 0.0002797218132573 0.0063900040220717 2284.413913831537 0.0007449925699094 0.0147272834705145 1976.8362887572343 0.0009265919079858 0.0192161199800089 2073.8493196837285 0.0012346262115666 0.0222973968089335 1806.003841489749 +r_0697 lactoylglutathione lyase 4e-13 1.9997999499870408e-11 4999.499874967602 2.0000000000000004e-12 4.468108413921743e-11 2234.0542069608714 6.000000000000003e-13 2.448999697816333e-11 4081.6661630272206 3.999825807060149e-13 2.8284887502209288e-11 7071.529828194828 8e-13 2.8275782995007477e-11 3534.4728743759347 2e-13 1.4142135623728843e-11 7071.067811864423 1e-12 3.1610122428868876e-11 3161.012242886888 1.6e-12 3.997198458808681e-11 2498.249036755425 2e-13 1.4142135623730082e-11 7071.06781186504 +r_0698 lanosterol synthase 0.0008623714804604 0.000224763998761 26.06347773015944 0.00138103621801 0.0001556333837369 11.26931949410874 0.0031963661048037 0.0002342655662669 7.329121839793739 0.0047546468706592 0.0003634469398359 7.644036449451798 0.0067337803677773 0.000739564167261 10.982897078141423 0.0079601043498033 0.0007283952514121 9.15057415585503 0.0089484761904713 0.0011285873998419 12.612062387154923 0.0105267723674424 0.0015452951672322 14.679667359499671 0.0119053701075431 0.0015038728803876 12.631886844364349 +r_0699 leucine transaminase -0.0052972341295872 3.91386141985294e-05 -0.7388499968299376 -0.0090052526068554 5.555684855763273e-05 -0.6169382579600158 -0.0248666591227361 7.006294243475762e-05 -0.2817545456707431 -0.0417474738052473 0.0001130242542304 -0.2707331580294222 -0.044956250460879 0.0001892860453234 -0.4210450012689807 -0.0629413536092948 0.0001833240819215 -0.2912617403488926 -0.0728889775769719 0.0003443759930364 -0.4724664887400879 -0.0917310883090498 0.0005384954221624 -0.5870369926804414 -0.0970609630075971 0.000488666059285 -0.5034630237975413 +r_0700 leucine transaminase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0701 leucyl-tRNA synthetase 0.0052972349873571 3.913894180184065e-05 0.7388560616105039 0.0090052534879615 5.555711399052114e-05 0.6169411451303541 0.0248666600221712 7.006320779435792e-05 0.2817556026096354 0.0417474746128088 0.000113024670254 0.2707341493163992 0.0449562512752725 0.0001892862958028 0.4210455508040787 0.0629413544927575 0.0001833245104954 0.2912624171704081 0.0728889784165868 0.0003443764443408 0.4724671024645051 0.0917310891266332 0.0005384958731178 0.5870374790541083 0.0970609637734482 0.0004886663252214 0.5034632938140844 +r_0702 leucyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0703 leukotriene A4 hydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0704 leukotriene A4 hydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0705 leukotriene A4 hydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0706 leukotriene A4 hydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0707 leukotriene A4 hydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0708 leukotriene A4 hydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0711 lysyl-tRNA synthetase 0.0048132280801653 3.5562827429440485e-05 0.7388560616105091 0.0081824459478778 5.04808757305114e-05 0.6169411451303721 0.0225946001195542 6.366155172407913e-05 0.2817556026095982 0.0379330193132744 0.0001026976371478 0.2707341493163679 0.0408486109325939 0.0001719912588969 0.4210455508040994 0.0571904202043499 0.0001665742002771 0.2912624171704067 0.0662291324599711 0.0003129108631209 0.4724671024644632 0.0833496446848571 0.0004892936529585 0.5870374790541015 0.0881925301477549 0.0004440170171798 0.503463293814101 +r_0712 lysyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0713 malate dehydrogenase 0.2490846924019438 0.145059593769377 58.23705679002417 0.480845566875574 0.2247082453140734 46.73189497704573 0.7054681044747447 0.4078459789296521 57.812107498936925 1.223019351348799 0.6795572314186367 55.56389853269217 1.8507159143933696 0.9041161538349484 48.85223857446002 1.5725777171149842 0.9543460902489004 60.68673616968975 2.572453148603946 1.3731237382538397 53.37798820550046 2.9449742390371925 1.5370605535124962 52.19266549560756 3.181114182077761 1.3203254147392405 41.50512490805543 +r_0714 malate dehydrogenase, cytoplasmic 0.0129634670563507 0.1193725558543348 920.8381934820002 0.0204174893026789 0.1812014843660833 887.481715699042 0.0281765498408505 0.34312887132064 1217.781713015727 -0.0241724705979308 0.5686841802761987 -2352.610909059824 0.0316886803201147 0.7061464212847919 2228.3869638981378 0.096223213236944 0.8203119021252836 852.5093628969898 7.031462811301913e-05 1.122103523858622 1595832.2670142353 -0.0373234991432006 1.2414296524815795 -3326.134154031312 0.006330351378209 1.0382390642149342 16400.970533624237 +r_0715 malate dehydrogenase, peroxisomal -0.0010317580894008 0.0039933839613796 -387.0465375947416 -0.0021560117290827 0.0077048625447493 -357.3664484667378 -0.0016822741602905 0.0064567334075247 -383.8098188710008 -0.0026456021713064 0.009766485170058 -369.1592513788741 -0.0049836245927692 0.0192913248333639 -387.0942619023487 -0.0041877797592582 0.0151523630701002 -361.8233035441216 -0.007589850296055 0.0287946926424507 -379.3841975699749 -0.0120344210398921 0.0445650376811509 -370.3131005091577 -0.0109437578847069 0.0420129851287968 -383.8990735303717 +r_0716 malate synthase 2.5485757864102133e-05 0.0007719839625118 3029.0798752320347 0.0003275149153334 0.0050204159222411 1532.8816146068125 6.406190690366703e-05 0.0021164201110836 3303.71075944738 0.0004238491242259 0.0067845392982642 1600.6967834731315 0.0005088222394243 0.0104860778990502 2060.852904329424 0.0001581111622038 0.0052657672712444 3330.4209505821063 0.0009218867906703 0.0166256029919587 1803.432174125074 0.001390135481482 0.0262466071936469 1888.06109499946 0.0012861752124864 0.0251784511606089 1957.6221743484543 +r_0717 malate synthase 3.4076750145296944e-05 0.0008021713275869 2354.0135845308287 6.876667228814223e-05 0.0015362493163629 2234.002701084381 6.227900303070467e-05 0.0013092882146074 2102.294755685087 0.0001109159471819 0.0021299674489049 1920.3437404813244 0.0001397886425483 0.0034057095838575 2436.3278173178774 0.0001119133829763 0.0027953978417271 2497.8226619409947 0.00022996507879 0.0054166173426736 2355.408643422244 0.0002900860348765 0.0073918722783082 2548.1655059516897 0.0001860408885196 0.0058815242116552 3161.4148150198494 +r_0718 malic enzyme (NAD) 0.0024782855205722 0.018195752193368 734.2072591041425 0.0074973503981641 0.0416788129433494 555.9138993097541 0.0077775034337735 0.0315515345498059 405.676896429187 0.0181001988266204 0.0460662967584976 254.5071311081215 0.0145283545165301 0.0884100443581098 608.5344645019389 0.0295771769246925 0.0826837649775234 279.55259282536446 0.0381491380776963 0.145602737103499 381.6671737300005 0.036913920610904 0.1992774845291773 539.8437262454114 0.0579497896147951 0.204057647605353 352.1283665769431 +r_0719 malic enzyme (NADP) 0.0026944684118379 0.0052670818592672 195.4775879400431 0.0028125612190345 0.0054475860314566 193.6877318292307 0.0090678147872114 0.0127759638282572 140.89352427307415 0.0088414382782124 0.0168410976920689 190.4791637076697 0.0199764716458163 0.0232551147061031 116.41252328447868 0.0150897424600293 0.0342524967116325 226.9919238341055 0.019183653574616 0.0383889436617437 200.1127861928255 0.0375906278929942 0.0558672673205214 148.6202025663248 0.0196212537734613 0.0511816583606423 260.8480525840201 +r_0721 malonyl-CoA-ACP transacylase -7.600000000000002e-12 9.769415965024004e-11 -1285.4494690821057 -9.000000000000004e-12 9.444990289476612e-11 -1049.443365497401 -7.000000000000001e-12 9.875702805430514e-11 -1410.8146864900732 -3.8e-12 8.115957969010801e-11 -2135.7784128975795 -5.999999999999998e-12 8.925017153274383e-11 -1487.5028588790644 -1.6e-12 6.927048202471001e-11 -4329.405126544376 -1.0400000000000007e-11 1.1087965935992347e-10 -1066.1505707684942 -1.0200000000000007e-11 1.1357173815673423e-10 -1113.4484133013152 -1.4e-12 7.070388820963914e-11 -5050.2777292599385 +r_0722 mannose-1-phosphate guanylyltransferase 0.0210693043748325 0.0001556711744524 0.7388529382980082 0.0334436110962996 0.0002063269692742 0.6169398653756181 0.0683715710219887 0.000192640368199 0.281755070593685 0.0903990430019414 0.000244740476155 0.2707334812712646 0.1601433329215432 0.000674275776632 0.4210451751759302 0.1671155363771196 0.0004867442054197 0.291262090869457 0.1813989416761459 0.0008570495307965 0.4724666653935875 0.1986324409907328 0.0011660464958151 0.5870372885713679 0.2415558092783578 0.00121614445023 0.5034631350259089 +r_0723 mannose-6-phosphate isomerase -0.0210924983030655 0.0006859903743248 -3.252295505578848 -0.0334762657325938 0.0008398039503593 -2.5086548095525765 -0.0683954146753698 0.0009911249352745 -1.4491102071370694 -0.0904716437190236 0.001952632559596 -2.158281290500578 -0.1601902155691638 0.0024361028540502 -1.5207563367054988 -0.1671441990092153 0.0015113359700031 -0.9042108424712813 -0.1816103470465989 0.0061530118793248 -3.388029360323856 -0.1986859203886808 0.0039536449183126 -1.9898968737081848 -0.2416071837384637 0.0038271632584303 -1.5840436526809518 +r_0724 methenyltetrahydrifikate cyclohydrolase 6.612003873198163e-10 6.38197682896409e-10 96.5210691244981 2.2480393659937348e-10 8.637246568454387e-10 384.2124252408868 2.8891337527430837e-10 2.389951334584833e-09 827.220730890599 3.4989483335750587e-10 8.037289899168681e-10 229.7058753924657 4.037252663412423e-10 8.690696583760181e-10 215.2626379448472 3.0580000000000664e-10 7.32662076774644e-10 239.5886451192375 -8.603012622367846e-11 9.307779192745571e-10 -1081.9209039104894 -2.0843324136044558e-10 9.242586925528735e-10 -443.43152105692417 2.1031198125100358e-10 8.945568974338024e-10 425.347567985756 +r_0725 methenyltetrahydrofolate cyclohydrolase 0.0050355484451712 0.0020620904491753 40.9506625073338 0.0110416646425017 0.0036980893397084 33.49213600885583 0.0288990134850601 0.0032218043145099 11.148492373885 0.0390652109899221 0.0045444132699367 11.632890632816723 0.0484348702443791 0.0069994496984965 14.451261380861965 0.0486815638379709 0.004934972271908 10.137250907413945 0.0643710270715432 0.0102009217791688 15.847070092312457 0.0740613070446351 0.0165980395569768 22.41121608476825 0.0824129839743338 0.0157665540069015 19.131152940429555 +r_0726 methionine adenosyltransferase 0.0037094837106805 0.0025856330888422 69.70331427518029 0.0058762552216364 0.003536863443845 60.18907127829046 0.0129545235335757 0.0043164811663531 33.320261877371 0.0191716775166393 0.0061056626687471 31.84730529421804 0.027817847556755 0.0124925540556059 44.90841367261847 0.0319493894334261 0.0094575085123264 29.601531296970112 0.0373572763732262 0.0189007740822228 50.59462551121352 0.0451216094656578 0.0288186139620662 63.868763333896894 0.0504813010301121 0.0284765035133912 56.41000317405639 +r_0727 methionine synthase 0.0048207378741064 0.0023546125524186 48.84340559286489 0.0077573977167123 0.0029759163424293 38.36230203871261 0.0183829130773067 0.0038917311181013 21.170372191476247 0.0283767005075633 0.005616147068104 19.79140269182159 0.0374600828006425 0.0112898363591977 30.13831127731534 0.045802864556384 0.0088504869665649 19.32299879556634 0.0531996774842294 0.0174298030103502 32.76298623336037 0.0647366791203844 0.0258851639459521 39.98531326856615 0.0712448880090433 0.0254228752692324 35.68378866144824 +r_0728 methionyl-tRNA formyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0729 methionyl-tRNA synthetase 0.0011908510101029 8.79867487289696e-06 0.7388560616106168 0.0020244363782175 1.248958097421053e-05 0.6169411451303284 0.0055901781355681 1.575064009282151e-05 0.2817556026096226 0.0093850890947005 2.540864112312358e-05 0.2707341493163977 0.0101064418266077 4.255272365553687e-05 0.4210455508041037 0.0141496036618813 4.121247764562396e-05 0.2912624171703774 0.0163858907108973 7.741794305476295e-05 0.4724671024644176 0.0206217131022131 0.000121057184733 0.5870374790541892 0.0218199017085397 0.0001098551958488 0.5034632938141771 +r_0730 methionyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 0.0051924351006522 0.0050787681533421 97.8109125081645 0.0112818431735641 0.0098086902201213 86.94226704999187 0.0290894494491075 0.0083268600329857 28.625017628998734 0.0395375775482591 0.0139767748637781 35.35061005373494 0.0502457388260406 0.0411606585235532 81.91870491955243 0.0516791668353855 0.0481678595218073 93.205565165625 0.0661340265933702 0.0513250554890281 77.6076372978224 0.0760192109632276 0.0659639956856229 86.7727970993166 0.0888603386876867 0.1135482427653842 127.78281564339628 +r_0732 methylenetetrahydrofolate dehydrogenase (NADP) 0.0001568861508977 0.0047414762720558 3022.2401690159027 0.0002401783299457 0.0091187737732653 3796.667990541256 0.0001904357625759 0.0076673392207954 4026.207639302648 0.0004723666293002 0.0133274336024221 2821.417258489616 0.0018108685828483 0.0405832579389589 2241.0934908995705 0.0029976025690607 0.0479787377567362 1600.5703441790677 0.0017629994089056 0.0503226432387082 2854.3766370259227 0.0019579038019705 0.0640291327820219 3270.290027404812 0.0064473549827245 0.112543842584601 1745.581604955191 +r_0733 methylenetetrahydrofolate dehydrogenase (NADP) 9.941187041830736e-11 1.3579243948057292e-09 1365.9579978646684 4.819976695075125e-10 2.8797922634785713e-09 597.4701633767307 4.744001106424229e-10 2.1044440265425742e-09 443.6010825741122 -9.747728346462306e-11 8.391203820063345e-10 -860.8368557078965 3.590483964799714e-10 8.65405248348856e-10 241.02746505292657 2.868768579834112e-10 5.914097105837669e-10 206.15455521266392 4.624505154987613e-10 7.44798424538218e-10 161.05472900920856 4.378670959107117e-10 7.84439669287502e-10 179.15017515896247 1.2763801265905892e-10 1.225172521729582e-09 959.8805999919548 +r_0734 methylisocitrate lyase 1.40758437259623e-05 0.0004448215083064 3160.1765191950544 0.0001412729342032 0.001538134785996 1088.7682022539052 9.688439548988284e-05 0.0015171922548135 1565.9820625829648 0.0001382676929956 0.0021501463748862 1555.0605700451931 0.0002789801104243 0.0040299106045713 1444.5153808428015 0.000140783099587 0.0025941983339369 1842.6915883692525 0.0003923802770424 0.0058898748220155 1501.0629143773308 0.00048450121511 0.0077971879661726 1609.3226854758857 0.000519284440575 0.0079842360214296 1537.5457836919152 +r_0735 mevalonate kinase (atp) 0.0049965492571161 0.0017062423825869 34.14841513184215 0.0078202288551558 0.0021863964868402 27.95821615116435 0.0184066827112203 0.0040933408007827 22.23834063422812 0.0272195582120918 0.0063724240869779 23.411195866313133 0.0400986002966669 0.0060493241491345 15.086122967831786 0.0460173494538898 0.010039213135946 21.816148159522896 0.0529092384645643 0.0096722221614578 18.280781281582435 0.0628305275934574 0.0108138318195776 17.211110957953714 0.0696737533556213 0.0147321536737934 21.144481191646413 +r_0736 mevalonate kinase (ctp) 4.179621969199231e-05 0.0005215418399235 1247.820601401155 5.618393702633935e-05 0.0006959866154791 1238.7644090389272 9.658223512634692e-05 0.0013277859162345 1374.7724045706916 0.0001546575717265 0.0021729771942628 1405.024771825822 0.0001980706367679 0.002809231635146 1418.297876447857 0.0001914297431389 0.0029469814297723 1539.4584882417068 0.0002229731017781 0.0036339207794699 1629.7574687215292 0.0003966056567741 0.005605841540406 1413.454761589103 0.0003331427919587 0.0051230053343792 1537.7806328206907 +r_0737 mevalonate kinase (gtp) 0.0001164006030247 0.0008125970566641 698.1038203823394 1.1449484255696091e-05 0.0003058062315437 2670.917088615634 3.3042324684247695e-05 0.0009235108662526 2794.9330898407447 3.845592965752907e-05 0.0011478445965528 2984.8312257045377 6.524103033754554e-05 0.0018500498750727 2835.7152937360274 7.619519915375233e-05 0.0023387894268756 3069.470849674268 5.292892020874192e-05 0.0016730944561369 3161.021327354916 9.617013203534312e-05 0.0031064900242279 3230.202515565149 0.0001260180800311 0.0040131184186718 3184.5576584572214 +r_0738 mevalonate kinase (UTP) 6.136072665155317e-05 0.0006061013157449 987.76750019086 0.0004223766423308 0.001819491863218 430.7747353587585 0.0006851574459103 0.0035599067139217 519.5749874967627 0.001157002491371 0.005637908041827 487.2857304867247 0.0001767407293436 0.0027994052528387 1583.9050021089877 0.0015914163983136 0.0086884217509595 545.9552735642575 0.0006275389046649 0.0058788595029474 936.8119584690854 0.000117741328749 0.0038297210072593 3252.65652082198 0.0015772992632437 0.0107656036125521 682.5339910710861 +r_0739 mevalonate pyrophoshate decarboxylase 0.0052161068064845 0.0014114334713477 27.059136703126423 0.0083102389187687 0.0009838252158585 11.838711563834153 0.0192214647169411 0.0014880689307817 7.7417041453151345 0.0285696742048471 0.0022591287033084 7.907436000530989 0.0405386526931157 0.0046798995841252 11.544289889338064 0.0478763907940958 0.0045750261435385 9.555912773823174 0.0538126793906166 0.0069803570654712 12.971584289275276 0.0634410447110162 0.00982850863125 15.492349906941833 0.071710213490855 0.0095573899925742 13.327794643636192 +r_0747 MIPC synthase 1.6779129580027243e-10 2.8580100128689357e-09 1703.3124389663928 1.7282765572385636e-11 3.353594976937354e-09 19404.2727877749 5.094352552928104e-11 2.947028866591542e-09 5784.893832873158 -8.69664483939585e-11 3.0945208877422802e-09 -3558.292818540874 1.0272922811571896e-10 2.991617262270609e-09 2912.1383632910324 1.603385341191452e-10 3.628575708074561e-09 2263.0715242651645 -3.914075132562606e-11 2.965362416143375e-09 -7576.150982574282 2.7150290043572927e-10 2.387039085795346e-09 879.1946907250116 2.9218117063518135e-10 2.3559433158729167e-09 806.3296175969384 +r_0748 MIPC synthase 2.1834662711400599e-10 2.527489908272933e-09 1157.558484726786 -2.318354292934386e-10 3.053746642690139e-09 -1317.204472153802 -1.95654353933325e-10 3.5487029589439343e-09 -1813.7613028296112 -3.2751849563497107e-10 3.2393612068013832e-09 -989.062068241711 -7.153490715393531e-11 3.013146162993354e-09 -4212.134023616461 4.1341868140982494e-10 2.641212055524415e-09 638.8709979233283 -1.5551620730436368e-10 3.273988059955485e-09 -2105.239136618025 1.769601421058624e-10 2.6624324038061593e-09 1504.5378988300197 -2.102384337906006e-11 2.580512126063223e-09 -12274.216847683696 +r_0749 MIPC synthase 3.0675932310738845e-10 2.261098615971698e-09 737.0920606641663 1.1812083459873507e-10 2.860014649278919e-09 2421.261802792533 2.3055072484147683e-10 2.5768794542450943e-09 1117.706073583988 -2.8888988247961884e-11 3.011832110142094e-09 -10425.536831856958 1.2687015082679692e-10 2.584282412792613e-09 2036.9506900962656 5.601500593782866e-10 2.468313383145822e-09 440.6521684359749 1.3713975826687008e-10 2.365234306504597e-09 1724.6889861814675 3.197858973036381e-10 2.221237030264928e-09 694.6013094992284 4.0320196903082226e-10 1.5768884245612411e-09 391.0914493675744 +r_0750 MIPC synthase 1.9740223683289238e-10 2.785570343467172e-09 1411.1138699128585 3.246067546056522e-11 3.203342891968972e-09 9868.380267873805 1.9414387265871479e-10 2.71523653808153e-09 1398.5692676763692 -9.093642081533544e-11 2.719153983105469e-09 -2990.170449557558 1.8613185728884505e-11 2.696662908073329e-09 14487.917046293514 4.971827199012214e-10 2.414580774476853e-09 485.6525936695013 1.3788878577324618e-10 2.3666071902152023e-09 1716.315925870153 3.0172176890820797e-10 2.127753479576716e-09 705.2038330797527 3.1942628654660735e-10 1.869278881218765e-09 585.1988267552986 +r_0751 MIPC synthase 1.7562521874020652e-11 2.9157051442367797e-09 16601.859147289288 -1.3863659814239031e-10 3.335452774867241e-09 -2405.896292580317 -2.390517400881949e-10 3.385352851726563e-09 -1416.1590501192682 -3.8055742649080116e-11 3.304617752177581e-09 -8683.624394484023 5.96195999446684e-11 2.880004342816809e-09 4830.633458610383 3.5184393730905235e-10 2.9084653161152127e-09 826.635052563227 -5.7170330907115616e-11 3.2676492798752277e-09 -5715.6382130867205 8.954239932025403e-11 2.63507902399801e-09 2942.828251199172 5.936497088566358e-11 2.884158312631657e-09 4858.350420463477 +r_0752 MIPC synthase 6.90230894523425e-11 2.928868523542607e-09 4243.317050542726 -1.2315897562797288e-10 2.857313125196826e-09 -2320.0202101614823 7.924619641961624e-11 2.979909796804511e-09 3760.3190202664136 -3.5467168088931264e-10 3.3858525980896316e-09 -954.6441908189172 3.628252544194067e-11 2.791874465820322e-09 7694.818460991317 4.1885985013067535e-10 3.490037577466094e-09 833.2232312018631 -1.9582924036533285e-11 2.798023689231393e-09 -14288.079165355944 7.323545778912055e-11 2.780973882199864e-09 3797.305248241364 6.761532153475406e-11 2.342777765395736e-09 3464.8622711814746 +r_0753 MIPC synthase 2.0420796089931487e-10 2.5452428978428874e-09 1246.397489419045 7.529433858103581e-11 2.809512661875584e-09 3731.373055162489 1.2521729408685695e-10 2.684454574655353e-09 2143.836915045681 9.407597082190635e-11 2.927745112894511e-09 3112.1072547175468 2.707900661306012e-11 2.7365855601786404e-09 10105.93039575829 4.5784579162099637e-10 2.369625437844428e-09 517.5597288892409 2.1849572080790767e-10 2.901295874121521e-09 1327.850203836358 3.0383370794501526e-10 2.287734428118297e-09 752.9560968042125 3.6419348231545535e-10 1.951663827949511e-09 535.886533592336 +r_0754 MIPC synthase 1.0163781728207628e-10 2.989256376114912e-09 2941.086749057984 -1.8067244794576828e-10 3.367831209943686e-09 -1864.0535666813985 -1.4583596084624592e-10 3.5911366561882505e-09 -2462.449340580933 -2.933845592326327e-10 3.3756182575979e-09 -1150.5780217019803 -4.08345356728484e-12 2.890631255230897e-09 -70788.88513364262 4.328043089526773e-10 3.145897762213688e-09 726.8637804984655 -7.280068096455748e-11 3.1482386418414443e-09 -4324.463178269092 2.4791031409027393e-10 2.5378715534447743e-09 1023.7055133255308 3.0627345281590016e-10 2.2521599877762287e-09 735.3428666669304 +r_0755 MIPC synthase 1.4280056054063915e-10 2.9266384587987347e-09 2049.458662990228 1.2129823923157035e-11 3.492781121572949e-09 28794.9861737472 1.1260564002033319e-10 3.7212205130986038e-09 3304.6484282906817 -9.452096461595918e-11 3.3045663581815723e-09 -3496.120010632668 5.001769836565935e-11 3.0192159269775674e-09 6036.29520276061 4.230527039214061e-10 2.9094167141773846e-09 687.719682963636 1.4560376157311174e-10 2.6505420766822662e-09 1820.380220981691 2.6305247311358235e-10 2.511154624814717e-09 954.6211807445868 2.2881909533327158e-10 2.230607773751261e-09 974.834626674148 +r_0756 MIPC synthase -1.6097310383125562e-10 3.279616222421883e-09 -2037.3690662384377 -2.1475964600561542e-10 3.185291466228969e-09 -1483.1890094220412 -1.7919004848799906e-10 3.2138561768772222e-09 -1793.5461282563715 -2.3184661253663768e-10 3.2726235584020318e-09 -1411.5468509960967 -8.558028794073388e-11 2.980296952716706e-09 -3482.4572625656783 2.6644121694322644e-10 3.159508359268403e-09 1185.818168643793 -1.9193686462273079e-10 3.2377821423014923e-09 -1686.8995691190676 4.006370024773144e-11 2.878192461822666e-09 7184.040525526947 -5.581599975967704e-11 3.0252837436014086e-09 -5420.101326908335 +r_0757 myo-inositol 1-phosphatase 0.0015477741085293 0.0058321173233336 376.8067504937912 0.0028272116941636 0.0107658387216309 380.7935126985891 0.0028449300336096 0.0090145588885913 316.86399250928315 0.0042302020340248 0.0133670405701476 315.9905948376071 0.0082490475748237 0.0276648380531278 335.37008730027577 0.0072937294382575 0.02254934183699 309.1606568062784 0.0121303004667001 0.0414868430581844 342.0100200491586 0.0174289405128766 0.0624372303519985 358.23881724692086 0.0172504699898242 0.0602429715508969 349.22510277362335 +r_0758 myo-inositol-1-phosphate synthase 0.0002379144650908 0.0005637452623028 236.95291586729704 0.0003589035536337 0.000597877807843 166.5845327497401 0.0008189306021048 0.0010104377393868 123.3850263733904 0.0012025001088026 0.0014005690541634 116.4714284772926 0.0017577683167828 0.0028111431226662 159.9268285715459 0.0020174318642967 0.0023210881506268 115.05162537104825 0.002450428946111 0.0046854429137747 191.209091012854 0.0029379197423198 0.0067319226315458 229.13909235077128 0.003240802259401 0.006493027948612 200.3524877143259 +r_0759 N-acetyl-g-glutamyl-phosphate reductase 0.00312440564599 0.0019966514679592 63.90500127669979 0.0054746023696121 0.0043834382708851 80.06861457585043 0.0143499339320211 0.0048554362609746 33.83594854147704 0.0239043309399121 0.0078884097520724 32.99991860011232 0.026335567712415 0.013354293090009 50.70820282227532 0.0359540102750602 0.0108149342641162 30.07991092336671 0.0424240185469133 0.0203082133598037 47.86961267553304 0.0537932526431609 0.026649939197222 49.541416233008114 0.0568555534385222 0.026923313794912 47.35388570972949 +r_0760 N-acetylglucosamine-6-phosphate synthase 0.0007085715462321 5.235158308004288e-06 0.7388327030406702 0.0011247264338871 6.938834333338178e-06 0.6169352941547604 0.0022993733807543 6.478515713715e-06 0.2817513574759005 0.0030401696619305 8.230621946073948e-06 0.270729033617396 0.0053857093507502 2.2676280309944867e-05 0.4210453782988838 0.0056201884509851 1.6369349097987583e-05 0.2912597903210569 0.0061005474175171 2.882290024990333e-05 0.4724641622674853 0.0066801196804568 3.921462751387189e-05 0.5870348046098147 0.0081236566582483 4.08994902266207e-05 0.503461580753706 +r_0761 N-acteylglutamate synthase 1.66662615637266e-05 0.000480902268614 2885.483746761263 2.276493629346412e-05 0.0006568584769452 2885.39562983012 5.945233591300346e-05 0.0014009232085198 2356.380429811544 5.750573727610995e-05 0.0016592405571963 2885.3478553445566 8.207748387083478e-05 0.0028077152917386 3420.810628353562 6.158131330608368e-05 0.0017769630473634 2885.555620633153 0.0002433796230455 0.0059619636370641 2449.6560404107945 0.0002259579600833 0.0071425866840201 3161.024591204623 0.0002165524021892 0.0068453439474746 3161.05657488434 +r_0762 N-formyl-L-kynurenine amidohydrolase 0.0001863672338793 0.0007012758866742 376.2871144656452 0.0002869573137862 0.0010845775050998 377.9577843092618 0.0005763548767434 0.000858232028181 148.9068736661384 0.0008608083823484 0.0013125937061102 152.48384344600038 0.0012599511849628 0.0026833173616335 212.96994626919684 0.0014541754857708 0.0024778916984809 170.3983957044517 0.0016640384549398 0.0036682171006966 220.4406448545308 0.0021060111547125 0.0059033228332455 280.3082414846548 0.0023549918449674 0.0062853653062885 266.89541705719 +r_0763 N-formyltyrosine oxidase 8.228394178414e-06 0.000179639932221 2183.171203589948 3.889066454341255e-06 0.0001374652042437 3534.6581463086777 1.2094555877745574e-05 0.0003230467319769 2671.009462789576 1.902581506259495e-05 0.0004770249573223 2507.251099377032 2.02400513992642e-05 0.0007153790324683 3534.472409958272 1.8457808967426155e-05 0.0005325637142483 2885.302991206508 3.816076271333536e-05 0.0012062663090731 3161.012053492428 0.000103275743367 0.0024323147598469 2355.165579591457 7.759162052979143e-05 0.0020724783142419 2671.007900197501 +r_0764 NAD diphosphatase 0.0 0.0 1.520176216636544e-16 1.0054774571490284e-14 6614.216471388371 -7.609701433271197e-17 3.804474184095673e-15 -4999.505194069403 -3.4178749541251005e-16 8.049567668388076e-15 -2355.138141807352 -3.563034826084772e-17 2.519446087128653e-15 -7071.06781186626 0.0 0.0 0.0 0.0 -2.6449200565666427e-17 1.870240907694439e-15 -7071.067811864941 -7.603737267891473e-17 3.801505036492489e-15 -4999.521817442612 +r_0765 NAD kinase 2.612976294431686e-07 4.2953815075590624e-06 1643.8654712301147 2.152140480569785e-07 4.938021500195975e-06 2294.469875353407 9.060653245430802e-07 1.5629818963452937e-05 1725.0212032266986 6.962652470587669e-07 1.5851613141342604e-05 2276.662982721681 1.581134659105385e-06 3.0100593766347908e-05 1903.733726473304 4.223834060961664e-07 1.7241023694152983e-05 4081.842100167075 2.2580165634359343e-06 4.075364073322038e-05 1804.842417595342 1.6839109947299903e-06 3.8264224775644486e-05 2272.342475071257 2.9776262701730885e-06 5.403851540343534e-05 1814.8186004650645 +r_0766 NAD kinase 4.799999950213612e-12 2.2712832838631652e-10 4731.840223794352 -1.3139999999748264e-10 4.734753169604339e-10 -360.3312914531999 4.68800000007034e-10 5.350549660948274e-10 114.13288525742308 5.219999999706008e-11 3.514254685963677e-10 673.2288670807665 2.1200000017790734e-11 2.9794011751759585e-10 1405.377911639475 1.9620000009347635e-10 4.442353304073618e-10 226.4196382241147 1.817999999271832e-10 4.5868381085425804e-10 252.3013262035071 1.777999999013978e-10 4.4025665857242487e-10 247.6134189069613 1.181999995546274e-10 4.03312897456412e-10 341.21226647722324 +r_0767 NAD nucleosidase nuclear -5.791478399999201e-10 1.2162956069228934e-09 -210.0147014142472 -9.605503200371424e-10 1.6271388989705143e-09 -169.39652874277277 -7.980927992625505e-10 5.361817178421285e-10 -67.18287877519609 -9.256000000003727e-10 3.0932794370282136e-10 -33.41918147176932 -4.1892528434365215e-10 8.567560787403429e-10 -204.5128596338268 -9.375951999943238e-10 3.4202499141905277e-10 -36.47896143464935 -9.540817999999558e-10 2.696010238318164e-10 -28.25764246124692 -8.9762520000013e-10 4.4315851093953266e-10 -49.37010580133763 -9.124193999999887e-10 3.7189834898805926e-10 -40.75958369452293 +r_0768 NAD synthase 0.000137882593406 1.0160543501375216e-06 0.736898200881362 0.0002246354138675 1.380966960009216e-06 0.6147592386406585 0.0005217621208263 1.469579203298501e-06 0.2816569361093095 0.0007756137577339 2.099154355814433e-06 0.2706442910382693 0.0010936279857002 4.603501654481983e-06 0.4209385380289244 0.0012962054743199 3.774388284989234e-06 0.2911874976434072 0.0014511579204822 6.854674539536778e-06 0.4723589654018434 0.0017042454604807 1.0002369591847126e-05 0.586908976657965 0.0019324020839076 9.726825260337966e-06 0.5033541073744162 +r_0769 NAD synthase 2.963706042742488e-10 1.3920104413426652e-09 469.68573173827934 4.4856828012502703e-10 1.836710659732551e-09 409.46066432085087 5.41726346887794e-10 7.990143322104206e-10 147.49408752237005 3.2979999999510665e-10 8.470982676755717e-10 256.8521127010735 1.2939999999894484e-10 9.672862908964912e-10 747.5164535582525 5.598977063475833e-10 8.067665149942767e-10 144.09176995153427 4.448000000000358e-10 8.597097069104193e-10 193.28006000682336 6.52799999999791e-10 7.39974102476098e-10 113.35387599208562 7.83000000000034e-10 6.089213061073141e-10 77.76772747219513 +r_0770 NADH dehydrogenase, cytosolic/mitochondrial 0.5128320889858105 0.0990654976336369 19.317335978244127 0.8484656326356158 0.1891190862831522 22.28953996588944 1.8001047749673145 0.2889075453398473 16.049484972067425 2.7574209674541192 0.4360037605540396 15.812012953415474 3.7157945884653576 0.6991850699026799 18.816569464660503 4.294989162640974 0.7179203131851588 16.71529975977197 5.127009468168347 1.0026600349273511 19.556430335315085 6.490125298075176 1.234414835106416 19.019892196419004 12.81145094033337 1.3560843413805117 10.58493958019422 +r_0771 NADH kinase 7.399017118275092e-05 4.328568018775728e-06 5.850193275110077 0.000120801274502 4.97063981813188e-06 4.114724648907924 0.0002801166549392 1.5644970967810408e-05 5.585162714156543 0.0004170552650303 1.5813192670372003e-05 3.791630029948713 0.0005874508141167 3.018268590556593e-05 5.137908601071277 0.0006977243613828 1.7217118751549912e-05 2.4676103780332204 0.0007793487201252 4.069420994322164e-05 5.221566276093053 0.0009162354364747 3.856611681948645e-05 4.209192886914614 0.0010378280088444 5.43549390148825e-05 5.2373744543091565 +r_0772 NADH kinase mitochondrial -5.99999822922423e-13 2.2673756113705707e-10 -37789.604675662245 1.31400000018541e-10 4.734753169207551e-10 360.33129136525577 -4.6479999977619495e-10 5.385340876426915e-10 -115.86361615791743 -4.9599999931791865e-11 3.515174999639605e-10 -708.704637998699 -1.919999991638149e-11 2.9807571129144544e-10 -1552.4776697375212 -1.937999998433726e-10 4.4528779007586327e-10 -229.76666173154845 -1.8119999958960088e-10 4.5870321674927206e-10 -253.14747118553367 -1.7580000258273152e-10 4.410592600904809e-10 -250.88694744638488 -1.1740000178895988e-10 4.0354654393326647e-10 -343.73640356385005 +r_0773 NADH:ubiquinone oxidoreductase 1.1407379662774213 0.1261369223228378 11.057484369917251 2.1280237951469747 0.2573764327593236 12.094621937324137 2.959895335311266 0.3667806352014595 12.39167584156784 5.236289031162663 0.5906401590762841 11.279747079682087 7.191805232819988 0.9514425427170232 13.229537117816967 7.446201323445996 0.9018143545609424 12.111065970260332 10.395592110257065 1.2041769928344377 11.583534444818271 12.535163641544903 1.5997973011351694 12.762476397460109 5.77284383408972 1.3278106612252931 23.00098009553496 +r_0774 NAPRtase -7.448359646985528e-09 1.816635747152549e-08 -243.8974261786313 2.964580722367541e-09 1.984754027952628e-08 669.4889476200821 1.030119532104725e-07 4.815595472288734e-09 4.674792897528678 1.534411868342667e-07 6.4370185550541465e-09 4.19510477457844 2.158111499502284e-07 7.735990703387947e-09 3.5846112238279 2.560932277463326e-07 1.268611160359142e-08 4.953708348803882 2.8691496932340744e-07 9.682105044214477e-09 3.3745555580618425 3.371394509180309e-07 1.4994299506592543e-08 4.4475066521473705 3.819938964462091e-07 1.51816735421519e-08 3.974323590871752 +r_0775 NAPRtase -7.146105839810332e-10 9.942910352517923e-09 -1391.3746277205742 2.7445407851799964e-10 1.6117697635752052e-08 5872.63913977325 1.2344656893477678e-10 7.011147065516513e-10 567.9499338066549 4.6011703793200815e-10 6.379445186972913e-10 138.64831469065504 7.421979718401854e-11 3.5199596682768316e-10 474.2615584827778 8.289759828196107e-11 3.821424242622524e-10 460.98129762754365 5.880479612395132e-11 4.08459041234368e-10 694.6015770098076 1.1061088305595438e-10 4.3951025248294307e-10 397.3481092819858 5.1633016831327e-10 7.253241403302101e-10 140.476808221312 +r_0781 nicotinamidase 9.288470309685866e-09 1.4309194972480456e-08 154.05329936361062 1.4612175385560082e-08 2.2231562504317093e-08 152.14409845016354 1.0376816209014189e-07 2.193972793040566e-09 2.1143024496614813 1.5370010833079405e-07 1.989007784779385e-09 1.2940835282292933 2.1665837600904085e-07 3.006814850799251e-09 1.3878138044724295 2.568185642510432e-07 2.759378253882725e-09 1.074446569674535 2.878503380052199e-07 3.8857849068243485e-09 1.3499323758841246 3.385280569060637e-07 5.255454326043885e-09 1.5524427647372794 3.830244272052194e-07 4.602167090116243e-09 1.201533574163003 +r_0782 nicotinamide N-methyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0783 nicotinamide-nucleotide adenylyltransferase 5.364574187358166e-10 5.158481353483123e-09 961.5826295476148 1.653360622578822e-09 8.428040930905563e-09 509.7521264151049 -1.2780000009657475e-10 6.991172385607001e-10 -547.0400923571187 1.391999997103531e-10 6.74918115272444e-10 484.85496887701976 -5.174552801829154e-10 1.0718884977489161e-09 -207.14611267857072 -2.1025061341422512e-12 5.6505035202416e-10 -26875.086966377905 5.200000387767622e-12 5.329444301581826e-10 10248.930584925924 -4.09999942042416e-11 6.211248963526092e-10 -1514.9389857434458 -2.8799562071191205e-11 5.25762181289056e-10 -1825.5908891579527 +r_0784 nicotinamide-nucleotide adenylyltransferase -8.755184442741751e-10 2.090791964485992e-09 -238.8061585863341 -1.409118600079129e-09 2.4728418887075798e-09 -175.48855636202072 -1.3398191463196712e-09 1.2141527445084667e-09 -90.62064442380932 -1.2553999999955283e-09 9.875048724826128e-10 -78.66057611009481 -5.483252843426565e-10 1.6737940242473243e-09 -305.2556706834889 -1.4974929063419767e-09 9.68177574704873e-10 -64.65323278691872 -1.398881800000063e-09 9.64291417267729e-10 -68.93301616102843 -1.550425199999969e-09 1.0219940220770394e-09 -65.91701567267222 -1.6954194000000252e-09 9.032967003645086e-10 -53.27865779785787 +r_0785 nicotinate-nucleotide adenylyltransferase 0.0001378749273663 1.0175490718727398e-06 0.7380232877068946 0.0002246342302097 1.381143348327748e-06 0.614841000429077 0.0005217620490193 1.4693974175386068e-06 0.2816221341318733 0.0007756136565339 2.0990118452793657e-06 0.2706259524438256 0.0010936278038173 4.603332583541882e-06 0.4209231483941412 0.0012962053922157 3.774195205075048e-06 0.2911726203069811 0.0014511578094114 6.8544882245324574e-06 0.4723461624971448 0.0017042454140024 1.0002173882081238e-05 0.58689750900316 0.0019324020153123 9.726635043489196e-06 0.5033442816978874 +r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 0.000137882375726 1.0105949989558326e-06 0.7329399378525309 0.000224631265629 1.3725405762695744e-06 0.6110193843346509 0.0005216590370661 1.4692020798622438e-06 0.2816403005543986 0.000775460215347 2.099432754999262e-06 0.2707337802055614 0.0010934119926674 4.603033471728115e-06 0.4209788718796576 0.001295949298988 3.774694061054055e-06 0.2912686525623697 0.0014508708944419 6.853518984022138e-06 0.4723727666105143 0.0017039082745513 1.000107810419811e-05 0.5869493243015897 0.0019320200214158 9.726075280763898e-06 0.5034148286742981 +r_0787 nicotinate-nucleotide diphosphorylase (carboxylating) 7.146105839810332e-10 9.942910352517923e-09 1391.3746277205742 -2.7445407851799964e-10 1.6117697635752052e-08 -5872.63913977325 -1.2344656893477678e-10 7.011147065516513e-10 -567.9499338066549 -4.6011703793200815e-10 6.379445186972913e-10 -138.64831469065504 -7.421979718401854e-11 3.5199596682768316e-10 -474.2615584827778 -8.289759828196107e-11 3.821424242622524e-10 -460.98129762754365 -5.880479612395132e-11 4.08459041234368e-10 -694.6015770098076 -1.1061088305595438e-10 4.3951025248294307e-10 -397.3481092819858 -5.1633016831327e-10 7.253241403302101e-10 -140.476808221312 +r_0788 nucleoside diphosphatase 8.731329182525267e-05 0.0025195248237795 2885.614287481136 0.0001578006191716 0.0045532516466908 2885.4459954549784 0.0002133600138712 0.0048021014571354 2250.703573741496 0.0001270154111998 0.0044917084722881 3536.349195627314 0.0006330056870593 0.0141781220857697 2239.809590279419 0.0005035357643718 0.0113386805554411 2251.812355292232 0.0004641358619953 0.0147425438562598 3176.3423306444342 0.0014643400992399 0.0327745838615956 2238.1811355576506 0.0015442759598989 0.0329628445478421 2134.517754844754 +r_0789 nucleoside diphosphatase 7.326431547727603e-05 0.002316162842731 3161.379216665832 0.0001075060652783 0.0037997504764363 3534.452187974733 0.0001589429598935 0.0042453798453974 2671.008422292616 0.0004680798002983 0.0088346859773917 1887.4315814870035 0.0005352330905396 0.0133715063819703 2498.2585378807203 0.0003829913071638 0.0102297289193792 2671.008121602656 0.0010978170141833 0.0233899019760788 2130.582936308146 0.0012215530223128 0.030517459832589 2498.2509375490163 0.0013204407907749 0.0310981967012027 2355.1375357732486 +r_0790 nucleoside diphosphatase 0.0001442276585369 0.003229463703434 2239.143127048592 0.0004289156701142 0.0075708993113922 1765.1253705364354 0.0004056159855809 0.0067497386422865 1664.071161450598 0.0003332615965147 0.0074454063045647 2234.1026936282665 0.0009339350878163 0.0176269348162892 1887.3832931475165 0.00070840997311 0.013876623842195 1958.8408363696656 0.001805235420027 0.0300364254761116 1663.8508829868354 0.0022889554883119 0.0417319910812152 1823.189279752756 0.002043310593297 0.0385677650876002 1887.5135877100067 +r_0791 nucleoside diphosphatase 0.0001619356873301 0.0034491449256726 2129.94737759094 0.0002687641289375 0.0060043230354354 2234.049260654924 0.0003177697018387 0.0059974722353112 1887.3644027755904 0.0003016790779635 0.0071049657391535 2355.1403654220035 0.0008735008977276 0.0170555749105466 1952.553793008797 0.0008745885485403 0.0154375485064296 1765.1212712759589 0.0010066942677192 0.0224900951373298 2234.0541571060094 0.0015279120662374 0.0341343844437009 2234.05424945417 0.0019078594803725 0.0373712718318317 1958.806307083681 +r_0792 nucleoside diphosphatase 0.0001319485041557 0.0028207139375667 2137.73847275921 9.967169943260592e-05 0.00286003983545 2869.4602898628195 6.826974177311474e-05 0.0019023055689602 2786.454906014271 0.0002099397207647 0.0050036818721683 2383.389791098544 0.000618517538287 0.0134934391207824 2181.5774469632483 0.0004611650289944 0.0100062266224515 2169.7713385314723 0.0007503889274397 0.0177606434328799 2366.8584094752705 0.0019186658628574 0.035963617078893 1874.407512798173 0.0016381538921291 0.0330969375174991 2020.3802387870653 +r_0793 nucleoside diphosphatase 4.049598317332663e-05 0.0010934896967395 2700.24237233422 1.1518454790808922e-05 0.0008144762705654 7071.054975319623 3.308924068624283e-05 0.001187607599074 3589.105021584264 6.325742659622202e-05 0.0020272898079478 3204.824977924229 7.749833724638653e-05 0.0032020572350809 4131.775401710692 8.677162322509784e-05 0.0030970382468809 3569.183255736491 0.0002627438551628 0.0071178626902075 2709.050107297676 0.0002422831760258 0.008647533151721 3569.184329497228 0.0002327473692662 0.0083071827588316 3569.184384347986 +r_0795 nucleoside diphosphate kinase 0.0055592112147818 0.0159997990096946 287.80699979794605 0.0105294495066768 0.0300472535787101 285.3639552538498 0.0094478497711323 0.0249400849763882 263.9763076313103 0.0137781107961027 0.0367674771591373 266.85427126581976 0.02718469146285 0.0736226423615255 270.823902717956 0.0224083968208824 0.0591131517180935 263.79911151433106 0.0403077745364806 0.1101650346331995 273.30964286677386 0.0581131690323683 0.1644797804741822 283.0335760601335 0.056771034701375 0.1592534077801418 280.5187691537432 +r_0796 nucleoside diphosphate kinase 0.0001012294709555 0.0025732963767477 2542.0427000721097 0.000184597672915 0.0046806875900117 2535.6157074453663 0.000272280868551 0.0053372429169608 1960.1975509197948 0.0002621791402351 0.0062901741563284 2399.1894056432257 0.0008991562032032 0.0166616564340003 1853.0324736283435 0.0005513102487287 0.0116309388772184 2109.690306689922 0.0010954404859092 0.0225646521795929 2059.8702047116512 0.0025798381062092 0.0431861923244961 1673.988465421663 0.0018817643830719 0.0360044791579317 1913.3362009517305 +r_0797 nucleoside diphosphate kinase 2.6510101880439657e-05 0.0010820504262928 4081.653217225883 0.0001128275005556 0.0030136320701144 2671.0084467651304 9.505320162132083e-05 0.0025389429204831 2671.0756472968924 0.0001206411989879 0.003480872943912 2885.3103028752803 0.0002811172096126 0.0075086668417942 2671.009310365861 0.0002623526678585 0.0065542304965847 2498.251895085557 0.0003013779018104 0.0095266033966884 3161.0159004554885 0.0006408845041722 0.0171180975737222 2671.01130738555 0.0007036929321294 0.0175800200151799 2498.251611250364 +r_0798 nucleoside diphosphate kinase 0.0001058560907129 0.0026924914863895 2543.5395056207494 0.000150489620415 0.0043971715468878 2921.9101854076425 7.716562336855268e-05 0.0025061276724668 3247.725558435908 0.0001266174201583 0.0043652550630692 3447.594381253677 0.0005219675546915 0.0125811058605344 2410.3233519886244 0.0002624549969843 0.0078063341972439 2974.3515219525248 0.0008454988692764 0.0193968248402169 2294.1278273757057 0.0008863231266851 0.0243372106565081 2745.8620816460952 0.0013943852792254 0.0303541009963903 2176.8804826490177 +r_0799 nucleoside diphosphate kinase 8.243244055250765e-05 0.001880662801042 2281.45956669097 0.0001005957416262 0.0027851796587226 2768.6854470144845 0.0001348175862846 0.0029041309302761 2154.118769152158 0.0001687209013197 0.0040344001307972 2391.1679579950246 0.000239182528786 0.006577221229268 2749.8752783706286 0.0001527473180744 0.0046766314381345 3061.6782651826043 0.0003020045572559 0.0095464008118347 3161.012170999563 0.0006212921912522 0.0160007124408986 2575.392491035248 0.000474708340416 0.0139884348347687 2946.743009088361 +r_0800 nucleoside diphosphate kinase 0.0239924399198876 0.0042119173589828 17.555185604493307 0.0381475487880892 0.0075221778351896 19.718640054635035 0.0793245867615572 0.0059298062932509 7.475369914091572 0.1079176667385677 0.0100428565052297 9.306035618392938 0.182082839701981 0.0198674091421823 10.911192496063745 0.1946262250328836 0.0152634752262302 7.842455570235396 0.2139684287083665 0.0295664652608371 13.818143844546077 0.2388387255473558 0.0444234043423083 18.599749366649625 0.2845976327547034 0.0395666905476034 13.902677321882804 +r_0801 nucleoside diphosphate kinase 4.429310317596256e-05 0.0018078966048881 4081.666163027604 0.0001612579869723 0.0046527887961093 2885.307502262313 9.083255735247851e-05 0.0032104521007258 3534.4728743765104 0.0001677274236442 0.0053018843960741 3161.012242887072 6.69740901199591e-05 0.004735762916053 7071.037333348952 0.0002188833119235 0.0077363714104437 3534.472931013666 0.0004026776165009 0.0142325311264087 3534.472874376051 0.0007622897250184 0.0240963020630674 3161.042484533489 0.0007933894326295 0.0231159109626273 2913.564261375954 +r_0802 nucleoside diphosphate kinase 4.99430749085642e-10 6.238998163338651e-10 124.92218740558148 5.870000000000278e-10 5.367388729387171e-10 91.4376274171536 -1.6779999999999866e-10 5.728078052508895e-10 -341.3634119492814 1.1740000000000024e-10 4.72082421153827e-10 402.11449842745 2.1179999999999957e-10 5.63031225450376e-10 265.83155120414415 1.641999999999988e-10 4.94860927400326e-10 301.3769350793725 1.0600000000000059e-10 4.795935800241718e-10 452.4467736077068 7.680000000000049e-11 4.4423105277056045e-10 578.4258499616635 4.739999999999986e-11 4.3126608733777085e-10 909.8440661134432 +r_0803 nucleoside diphosphate kinase 0.0001177927810442 0.0022588040468694 1917.6082157537944 0.0001903261580828 0.0038218410826299 2008.0482478745505 0.000125815733843 0.0028947723628935 2300.8031463741486 0.0001854499654189 0.004267552587065 2301.188127711499 0.0006114329546553 0.0110092659814584 1800.567976854359 0.0004377378390172 0.008381605458843 1914.754611495357 0.0005581663595498 0.0128302685591292 2298.645975274537 0.0005937627497886 0.0159529885401642 2686.7614288440054 0.0008253197374734 0.0187297456264845 2269.3926700241223 +r_0804 nucleoside triphosphatase 5.86718493168533e-05 0.0020738750680435 3534.70206272818 0.0001074876703476 0.0037991227072168 3534.473019024526 6.647545389717708e-05 0.0027149761458842 4084.178424842001 0.0001676047810109 0.0052980097729698 3161.013511079254 0.0004685572948854 0.0125152056199894 2671.008595234623 0.0002187859927159 0.0077327464755749 3534.3882757683155 0.0005032322606744 0.015907235022685 3161.012571286052 0.0011767657314063 0.0295516065817859 2511.256556261923 0.0008289922409129 0.0241488361965793 2913.035249881946 +r_0805 nucleoside triphosphatase 2.9528715764813595e-05 0.0014762881077412 4999.499874967152 3.764279333326682e-10 2.19185761014309e-08 5822.781510228775 2.2708132452861183e-05 0.00160570744455 7071.0678118654005 6.709098764880708e-05 0.0033542138436164 4999.499874967272 0.0 0.0 0.0001061354045279 0.0053088137565267 5001.925399106345 0.0002013388290366 0.0100659345059472 4999.499874966928 0.0001527911928561 0.0108039687684114 7071.067753613662 0.0001467775599531 0.0103787407968859 7071.067811864954 +r_0806 nucleoside triphosphatase 3.724123009655088e-05 0.0015706095325689 4217.394346258251 0.0001611399110351 0.00464938227686 2885.307709922294 0.0001353941610666 0.0039066445252834 2885.3862637099537 0.0002678663027109 0.0066916465823488 2498.129296080568 0.0002622189775147 0.009269817589759 3535.1436717572683 0.0003274692558068 0.0094482880750439 2885.244311489405 0.0007036602881389 0.0187948314642857 2671.009261300678 0.0003516449639316 0.0153771776818054 4372.927031252648 0.0005866129115248 0.0207291247515669 3533.6973231090974 +r_0807 nucleoside triphosphatase 5.3151161020357394e-05 0.0018611363989235 3501.5912412726693 0.0001612579971253 0.0046527887957574 2885.307320381653 0.0001044574958402 0.0032815435025293 3141.510789753901 0.0001878547661988 0.0053959051131464 2872.381266832002 8.706631176823964e-05 0.0049440094160751 5678.441311761952 0.0002352995714958 0.0078225137896009 3324.491302670107 0.0004932801144936 0.0147026474248717 2980.5879038855333 0.0008081270848346 0.0243118734713069 3008.4220573157063 0.0008374227053645 0.0233231665773631 2785.112754640389 +r_0810 nucleoside-diphosphatase (GDP), Golgi 0.0002037706048308 0.0038487198036012 1888.751229254452 0.000214609378415 0.0053615214382578 2498.2698695906806 0.0001580284276662 0.0042211809376571 2671.152905837458 0.0003006227764615 0.0070804107482235 2355.247606838723 0.0004018426874006 0.0115944044083302 2885.3092943729785 0.0004377542193405 0.0109361564683719 2498.2412470740446 0.0009026864168597 0.0212606079427944 2355.259539271161 0.0012195636729266 0.0304682461519379 2498.290727110749 0.000880665323509 0.0254099044924004 2885.3077115780407 +r_0811 nucleoside-diphosphate kinase (ATP:UDP) 0.046968458817009 0.007830053036192 16.67087495184427 0.0745330118424921 0.0097026019157282 13.017858363529433 0.1520878828616976 0.0105094943688358 6.910145746714594 0.2023558885219842 0.0175885423832251 8.69188562373578 0.3544392798270095 0.030971932490912 8.738290097538993 0.3720780770364801 0.0269085303183376 7.2319580160858 0.4050660525189927 0.0515091668321349 12.716238873095843 0.4446189579594184 0.0654808792705429 14.72741503670196 0.5401661344057257 0.0702600339895828 13.00711568430345 +r_0812 O-acetylhomoserine (thiol)-lyase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0813 O-acetylhomoserine (thiol)-lyase 0.0018002216946121 0.00082126599737 45.620269982746144 0.0030297993423521 0.0010099801221989 33.33488485791383 0.008247183892837 0.0011898562027462 14.427424175416744 0.0139000480829617 0.0023619061891718 16.992072078276067 0.0149625634558043 0.0029912783622036 19.99175055156268 0.020935322685203 0.0035969184269655 17.181098572260424 0.0242916981660722 0.005353817710655 22.039701275938743 0.0305853784136856 0.0070375949164109 23.00967089968022 0.0322307015324247 0.0054997472122402 17.063690676131944 +r_0815 O-succinylhomoserine lyase (L-cysteine) 6.645448365922978e-07 4.696494438568026e-05 7067.234865071043 4.537977223247486e-06 0.0003208614520362 7070.583131014498 1.7244625592646523e-05 0.0006695870486166 3882.873797516158 5.242011567228703e-06 0.0003706463200557 7070.688709901421 2.204458389826245e-05 0.0012264877023638 5563.669099059427 1.7375853671399638e-05 0.0012286326501601 7070.919641677403 3.41591700994339e-05 0.0018830526967862 5512.583272090131 1.150977318927348e-05 0.0008138369288325 7070.833764048177 4.803111718354145e-05 0.0026771993659655 5573.885270532278 +r_0816 ornithine carbamoyltransferase 0.0028611602688849 0.0005202972776092 18.1848351267648 0.0048699996806793 0.0009773263798198 20.06830480291853 0.0133500149754676 0.0006530119353317 4.891469683979465 0.0223914381480339 0.0006827256038898 3.0490475840640583 0.0241726666143583 0.0020886653452032 8.640607916888426 0.0338064495054802 0.0018183514771727 5.3787117658657 0.039132225671546 0.0023743961335675 6.067623532320614 0.0494180528015937 0.0056859661026375 11.505848126930156 0.0521915568105131 0.0045791989376262 8.773830898073147 +r_0817 ornithine decarboxylase 4.232928987476165e-05 0.0008148956924104 1925.1343332747017 1.6412728334442712e-05 0.0004109534424357 2503.870374637111 2.0308059764566816e-05 0.0005354999734375 2636.8839743708804 3.471354474547243e-05 0.0009169343292957 2641.430991905036 0.000103745902681 0.0022408396531228 2159.930749276786 8.240761934908679e-05 0.0018835518789621 2285.652581447915 0.0001649442731496 0.0035788219096866 2169.7157720892515 0.0002139846095423 0.0048604224609285 2271.3888028314727 0.000204666336398 0.00464486609599 2269.48221077056 +r_0818 ornithine transacetylase 0.00312440564599 0.0019966514679592 63.90500127669979 0.0054746023696121 0.0043834382708851 80.06861457585043 0.0143499339320211 0.0048554362609746 33.83594854147704 0.0239043309399121 0.0078884097520724 32.99991860011232 0.026335567712415 0.013354293090009 50.70820282227532 0.0359540102750602 0.0108149342641162 30.07991092336671 0.0424240185469133 0.0203082133598037 47.86961267553304 0.0537932526431609 0.026649939197222 49.541416233008114 0.0568555534385222 0.026923313794912 47.35388570972949 +r_0819 ornithine transaminase 0.0002429995815694 0.0018289169137174 752.6420012350991 0.000631780672522 0.0043673063220701 691.2693774939634 0.0010022155801908 0.0048276466865817 481.69742937567327 0.001494849062291 0.007843500613243 524.7018452299076 0.0021372932436509 0.0131847905810124 616.8919786828171 0.0021378664835526 0.0106566345306141 498.47053651850695 0.0031938582657896 0.0200190439080471 626.7981307272534 0.0044155267880542 0.0262476314490088 594.4394113975053 0.0046305730809667 0.026563723565869 573.65952553595 +r_0820 orotate phosphoribosyltransferase -0.0024701106957942 0.0004401585674912 -17.819386323079108 -0.0040302650511452 0.0007797818850133 -19.348153908431325 -0.0092811312718676 0.0008659586475509 -9.33031353813272 -0.0137847495071843 0.0012153660941694 -8.816744138412211 -0.0195994106820898 0.0032437220889671 -16.55010011056755 -0.0230521584841813 0.0017647724722386 -7.655562811828073 -0.0258180671812165 0.0031838440253061 -12.331844994277908 -0.0307712975186701 0.0074638682578432 -24.255942581929187 -0.0347037674799232 0.0067703518754673 -19.50898235871385 +r_0821 orotidine-5'-phosphate decarboxylase 0.0024701106957942 0.0004401585674912 17.819386323079108 0.0040302650511452 0.0007797818850133 19.348153908431325 0.0092811312718676 0.0008659586475509 9.33031353813272 0.0137847495071843 0.0012153660941694 8.816744138412211 0.0195994106820898 0.0032437220889671 16.55010011056755 0.0230521584841813 0.0017647724722386 7.65556281182807 0.0258180671812165 0.0031838440253061 12.331844994277908 0.0307712975186701 0.0074638682578432 24.255942581929187 0.0347037674799232 0.0067703518754673 19.50898235871385 +r_0831 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.2570514953227088 0.041250172374932 16.047435290405744 0.4206959234545128 0.0803620165321932 19.10216193023849 0.5625845839429333 0.1057386380974022 18.79515385159008 0.9116500452284146 0.2081965466764561 22.83733190890068 1.2191777160071438 0.3125867279353267 25.63914381236075 1.619236585900537 0.2591089894004335 16.00192286023047 1.9952435740722632 0.3695809127440172 18.52309750782497 2.4501116041961133 0.549000537487808 22.40716449600001 1.6857335347189208 0.5460796092784829 32.3941831868188 +r_0832 oxoglutarate dehydrogenase (lipoamide) 0.2570514953227088 0.041250172374932 16.047435290405744 0.4206959234545128 0.0803620165321932 19.10216193023849 0.5625845839429333 0.1057386380974022 18.79515385159008 0.9116500452284146 0.2081965466764561 22.83733190890068 1.2191777160071438 0.3125867279353267 25.63914381236075 1.619236585900537 0.2591089894004335 16.00192286023047 1.9952435740722632 0.3695809127440172 18.52309750782497 2.4501116041961133 0.549000537487808 22.40716449600001 1.6857335347189208 0.5460796092784829 32.3941831868188 +r_0841 pantetheine-phosphate adenylyltransferase 3.967140312076874e-05 0.0008848860573219 2230.538845899128 0.0001556850481813 0.0020118262970998 1292.2411757593754 4.981609505464596e-05 0.0010656519255735 2139.171937111028 0.0001098301739132 0.0017981209183906 1637.1829838045194 0.0002003831856752 0.0040195740520383 2005.9437814074545 0.0001690922225225 0.0031881480188338 1885.4492366781008 0.0003941303398992 0.007104097696264 1802.474201321124 0.0006587538877613 0.0115723108151397 1756.6971565763972 0.0005519866210736 0.010321042291261 1869.7993569456623 +r_0842 pantothenate kinase 4.31481878771459e-06 3.1347991865955515e-08 0.7265193142110947 7.030580687703139e-06 4.356264692394595e-08 0.6196166271178616 1.6327739907715824e-05 4.600913435893524e-08 0.2817850763117142 2.42722233178113e-05 6.601518202962726e-08 0.271978306911771 3.422437906163664e-05 1.440882688870016e-07 0.4210106153496745 4.056432933484544e-05 1.1858617519527858e-07 0.2923410226171569 4.541354834459573e-05 2.146723121155822e-07 0.472705436903233 5.333381251186711e-05 3.130757436778091e-07 0.5870117453316277 6.0474116457881496e-05 3.044204703130784e-07 0.5033896948706948 +r_0843 pantothenate synthase 4.3147969881399005e-06 3.129227218692753e-08 0.7252316220888427 7.030547087741129e-06 4.34988907455256e-08 0.6187127431572544 1.6327724306128466e-05 4.5985109812127126e-08 0.2816382059737928 2.4272181125290883e-05 6.595842952393127e-08 0.2717449626115576 3.4224336581093715e-05 1.4398309804550757e-07 0.4207038395159047 4.0564295146042406e-05 1.1848497563001853e-07 0.292091789598317 4.541351676309623e-05 2.14561032220084e-07 0.472460728684284 5.333376783807367e-05 3.129632509573029e-07 0.586801314895825 6.047408065625624e-05 3.043717571062925e-07 0.5033094406782094 +r_0844 peroxisomal acyl-CoA thioesterase 2.913367002724292e-05 0.0010925018938819 3749.963162417855 9.375746708356475e-05 0.0026548166796311 2831.578926150989 6.943790324430335e-05 0.0020925030864415 3013.488294828647 0.0001277437214706 0.0034213306028503 2678.276915266415 0.0001054973611561 0.0043925332080359 4163.642729921099 8.62397350879155e-05 0.0035889109916989 4161.551502958905 0.000241691064864 0.0085392814562243 3533.139076129558 0.0006068089772359 0.0163616424158101 2696.3415225558733 0.0003036362472397 0.0109787264455032 3615.749616623788 +r_0845 peroxisomal acyl-CoA thioesterase 9.754365872156694e-05 0.0017705605477687 1815.146746568892 0.0002373506424313 0.0032676211617434 1376.7062638935536 0.000113849872793 0.0024931264055129 2189.836795027109 0.0001465921517117 0.00355976488103 2428.346155959981 0.0004060728489227 0.0078386612757108 1930.3583818777904 0.0004712777708281 0.0076270034293218 1618.366895582628 0.0003171259079035 0.0093346365892475 2943.511191172448 0.0008565039931538 0.016384217054454 1912.917766340372 0.0008804279111469 0.0177258354825718 2013.320484067797 +r_0847 peroxisomal acyl-CoA thioesterase 8.140463571464016e-05 0.001579875109983 1940.7679871219864 0.000193058450486 0.0029516345006528 1528.8812757079024 6.733254076839096e-05 0.0017273598685063 2565.416140240606 0.0001689366551829 0.0036416567572831 2155.6344615325515 0.0002576462220745 0.0063046374112102 2447.0133349699145 0.0002052432092836 0.0048274963666644 2352.085793003412 0.0006971221130661 0.0127430514324776 1827.9511141066923 0.000527175942853 0.0136482650573218 2588.939279637279 0.0009383792079742 0.0165321625232784 1761.7784348576292 +r_0848 peroxisomal acyl-CoA thioesterase 0.000113572324601 0.0019067787525957 1678.9114419319378 0.0001264781793538 0.0027602600679402 2182.4002227437227 0.0002069708183131 0.003380898817535 1633.514736565225 0.0002985009702437 0.004498006325277 1506.864892802306 0.0003368616073218 0.0067812762604499 2013.074839357249 0.0002107163071768 0.0055500389626995 2633.891527931029 0.0006490672278389 0.0122069536833642 1880.6917311181187 0.0007560900373935 0.0180619674630887 2388.8646285241302 0.0004814638440423 0.0129351078908998 2686.620823341278 +r_0849 peroxisomal acyl-CoA thioesterase 0.0001616590885937 0.0019412718760142 1200.8430165609143 0.000318871923751 0.0037152196712007 1165.113449781525 0.0002950205223853 0.0031851216317918 1079.6271412033816 0.000375488536351 0.0043289543154279 1152.8858796850714 0.0006888478059543 0.0086100433206165 1249.919539002986 0.0005111360820188 0.0056179516157048 1099.110748260109 0.0010864537614028 0.0112448553242291 1035.0054207286105 0.001779501388382 0.0217034681812656 1219.6376087685635 0.0014997545315585 0.0180759605648353 1205.2612733932135 +r_0850 peroxisomal acyl-CoA thioesterase 4.64174714859706e-05 0.0013660162358298 2942.892389652673 7.24680352475643e-05 0.0022145160683837 3055.852226182999 7.220884277512895e-05 0.0021061189860212 2916.7050808169347 0.0001232429973777 0.0034837685922121 2826.7476987233326 0.0001504844700341 0.0052415319740342 3483.104916305255 0.0001085201860302 0.0040810661680078 3760.651651362602 0.0005013676656925 0.0115530388356229 2304.304730075592 0.0005043882796564 0.0147159695267298 2917.5875253791432 0.0004624592111737 0.0136100413333911 2942.971186334059 +r_0851 phenylalanine transaminase -0.0024295055140029 0.0023556116764315 -96.95848240946576 -1.404142409477195 37.39394713451881 -2663.116424810623 -0.0125550413381533 0.0193596429549232 -154.19816178614596 -1.218903162594012 34.62303459417891 -2840.507405075216 -0.0223485675858096 0.0471915416769031 -211.1613708382268 -2.2280767719877685 46.85588970305466 -2102.9746502519474 -1.832973099821704 42.39104190315636 -2312.6930726522824 -2.443063313046117 48.93376270580263 -2002.9674402825808 -0.0504960259713896 0.1258217952601218 -249.1716780473197 +r_0852 phenylalanyl-tRNA synthetase 0.0024372430664901 1.8007718132946178e-05 0.7388560616105994 0.0041432920529108 2.556167343732812e-05 0.6169411451304786 0.0114410810300973 3.2235886801403976e-05 0.2817556026096048 0.019207896815301 5.200233604446888e-05 0.2707341493163566 0.0206842460222246 8.709009759396077e-05 0.4210455508041471 0.0289591419295365 8.434709677577221e-05 0.2912624171703901 0.0335360159957793 0.0001584466430572 0.4724671024644059 0.0422052186639011 0.0002477604516738 0.5870374790541583 0.0446574791468177 0.0002248340154469 0.5034632938141023 +r_0853 phenylalanyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0854 phenylpyruvate decarboxylase 0.0001477218635184 0.0014402504869607 974.9744910176216 3.1974711892259696e-05 0.0005498130971175 1719.524788746129 9.973938194495288e-05 0.0013106337557702 1314.0584292908145 8.380418926627932e-05 0.0014002671648527 1670.8796745273946 0.0002014182768352 0.003169487378001 1573.5847946876818 0.0002961367986223 0.0037250023746909 1257.865416260511 0.0003019757654716 0.00476871846054 1579.1725713791773 0.0005073368894441 0.0074937311470936 1477.0720014671208 0.0002700363540178 0.0053573293045331 1983.9289135783968 +r_0855 phopshoribosylaminoimidazole synthetase 0.0023449246804801 0.0002829338294029 12.065796047016931 0.0038719214958873 0.0010230903188197 26.423322887782422 0.00886208077158 0.0008362145130136 9.435871039398544 0.0131844677905472 0.0013270928310142 10.065577557599688 0.0186309699037152 0.0024674059688484 13.243572297094316 0.0219398447660159 0.0011162616427227 5.08782835351583 0.0247854152299604 0.0039229085691191 15.827487789581795 0.0292495167731632 0.0061419597153137 20.99849978017101 0.0330699098225629 0.0059229816578712 17.91048626878961 +r_0882 phosphoacetylglucosamine mutase 0.0007085715862576 5.235149712073787e-06 0.7388314481707233 0.0011247271352592 6.938686650961745e-06 0.6169217789310731 0.0022993743987335 6.478302558520923e-06 0.2817419626003129 0.0030401704125069 8.230463246260732e-06 0.2707237466821443 0.0053857096488761 2.2676215868347768e-05 0.4210441584625627 0.0056201891301919 1.6369195204353745e-05 0.2912570168932125 0.0061005484728371 2.882266337072836e-05 0.4724601976209531 0.0066801214129222 3.921424891743436e-05 0.5870289848561279 0.0081236581114857 4.089917258946136e-05 0.5034575806635136 +r_0883 phosphoadenylyl-sulfate reductase (thioredoxin) 0.0019412402170335 0.0018793221244158 96.81038482128996 0.0030703003945363 0.0014835364225149 48.3189340415984 0.0083017687843415 0.0017495495907788 21.07441963547376 0.0139271403436655 0.0025017075816251 17.96282309141102 0.0150532852365792 0.0040550478811824 26.937959504871145 0.0211551691152078 0.0051983963285166 24.572700412872805 0.0244487714992052 0.0070626301289907 28.887464260608564 0.0307595850772754 0.009506262161093 30.90504028975375 0.032504105616499 0.0091574312025812 28.17315237227433 +r_0884 phosphoenolpyruvate carboxykinase 7.382045417661721e-05 0.0023334737161918 3161.012408036565 0.0001339009214053 0.0042326656344632 3161.0429488006694 6.314481380042016e-05 0.0025773607271263 4081.666524938283 9.863703761786996e-05 0.0040264429660331 4082.080183340472 0.0002642746962732 0.0093433492044431 3535.468713501561 5.472085169212023e-05 0.0038693486294088 7071.067992836114 0.0003961674161299 0.0140043221170763 3534.950515083105 0.0006057970444306 0.0214125736083428 3534.611765639389 0.0007124433255794 0.0225272283623474 3161.9677739312706 +r_0885 phosphoethanolamine cytidyltransferase 1.0629940231372316e-09 9.333266137040082e-10 87.8016802906818 1.1077999999999308e-09 9.294901561555331e-10 83.90414841628373 1.0515999999999464e-09 7.737293916055381e-10 73.57639707166007 1.0613999999999418e-09 8.693567715496987e-10 81.9066112257157 1.101599999999937e-09 1.0089008951345627e-09 91.58504857794304 1.0603999999999404e-09 7.454280465574487e-10 70.29687349655701 1.029399999999948e-09 7.916192090863433e-10 76.90103060874135 9.844000000002023e-10 7.199029740585901e-10 73.13114324039435 9.91999999999963e-10 7.076977937181103e-10 71.34050339900573 +r_0886 phosphofructokinase 0.2457590440836488 0.0411760054223258 16.754624667367597 0.345142033220908 0.0701050295224098 20.31193618122404 0.8360037569701703 0.1109528654700371 13.271814216738754 1.1447572817453602 0.1805702276294295 15.7736692754749 1.5901298965341442 0.3174161137414409 19.961646808432626 2.024655983707737 0.2668453808399129 13.179788714092602 2.25163139420428 0.378849124488208 16.8255392718084 4.003053277857246 0.6003963958534803 14.998461278908092 5.763313078064561 0.4593252067249732 7.969811816630028 +r_0888 phosphoglucomutase 0.0445372254407398 0.0020542687609138 4.612475834731203 0.0707151418005341 0.0037768901577799 5.340992129285939 0.1442620307171297 0.00293406883949 2.033846899911759 0.1907688833883875 0.0041844925211359 2.193487977081016 0.338179073386057 0.0108158366098938 3.1982572137297174 0.3527822151505101 0.00889042122614 2.520087704066112 0.3831138772764843 0.0137263708425435 3.582843550362329 0.4205015966185545 0.0264495312705407 6.289995444305931 0.5105037001532712 0.0227119476462944 4.448929094828411 +r_0889 phosphogluconate dehydrogenase 0.1518164702317644 0.1222602222635367 80.53159323022932 0.3113446573481205 0.2398666904572122 77.04217329446982 0.6569314830851107 0.3130776052331829 47.65757362744954 1.1019051598153384 0.5437055418911998 49.34231744429948 1.5851181390463351 0.9339281380598172 58.91851938693368 1.434243847273887 0.785794973508309 54.788101409805215 1.9803018417913665 1.1104391932423423 56.07423928050521 2.4134122385426204 1.624310642656044 67.30348908965968 3.0034807403086834 1.2410592511224603 41.3206994959758 +r_0890 phosphoglucosamine mutase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0891 phosphoglycerate dehydrogenase 0.0168496999524839 0.0046771249980354 27.75791267040333 0.0305004786678659 0.0073037062592908 23.946202086938754 0.077570531862674 0.0076087006195579 9.808751386451688 0.1169988206783611 0.0103914671498585 8.881685379056508 0.1427884936032249 0.0205731952537248 14.408160443860975 0.1709403565298379 0.0170743707902167 9.98849606777111 0.2061999479487082 0.0309176795084094 14.994028764789077 0.2497672902713572 0.0460181045601577 18.424391965081497 0.272286568050596 0.0460517981755045 16.9129893204821 +r_0892 phosphoglycerate kinase 0.53426304236538 0.0476553050802102 8.919820631654135 0.7785240397660106 0.0804937257433225 10.33927298732038 1.86227538797417 0.1317762888229958 7.076090339482251 2.611024749016613 0.1812734430753514 6.9426168075819366 3.651245631897685 0.3697394575997529 10.126392329501696 4.455223654005887 0.2806911794933977 6.300271350934672 5.076996678381364 0.4404610475515437 8.675622133595141 8.706819517746576 0.7378059268658352 8.473885617612845 12.41596839905295 0.6310225229247624 5.082346399761252 +r_0893 phosphoglycerate mutase 0.5174133430054964 0.0478226771465127 9.242644742929402 0.7480235615923487 0.0811106485379466 10.843328031711062 1.784704856693505 0.1317954077884428 7.38471727099001 2.4940259288272664 0.1803404974083442 7.230899058581295 3.508457139013244 0.3686292514548418 10.506876294875276 4.284283297973252 0.2809299758757977 6.557222208174146 4.870796731078659 0.4395132042989806 9.023435560236331 8.457052228056828 0.7337789112310505 8.676532808875068 12.143681831487006 0.6298801505812414 5.186896028089628 +r_0902 phosphomannomutase -0.021069304258797 0.000155670994581 -0.7388520886543 -0.0334436109966427 0.0002063267955085 -0.6169393476358002 -0.0683715709250906 0.0001926401940157 -0.2817548162332161 -0.0903990429459696 0.0002447402890142 -0.2707332744225245 -0.1601433327598525 0.000674275615815 -0.4210450751803588 -0.1671155362696838 0.0004867440161562 -0.2912619778036413 -0.1813989415591214 0.000857049339169 -0.4724665600596604 -0.1986324408949263 0.0011660463077908 -0.5870371941951235 -0.2415558092098074 0.0012161442818323 -0.5034630654550089 +r_0903 phosphomethylpyrimidine kinase 7.196804958198611e-05 0.001409711595915 1958.8020018649024 7.98881316422358e-05 0.0019591279494597 2452.339176278871 7.673153946926999e-05 0.0018046556832627 2351.9086098689945 0.0001007913068698 0.0025141497055371 2494.4112578907057 0.0002987550272904 0.0060901043241276 2038.4943407854544 0.0002364703755669 0.0048611648485491 2055.718327039671 0.0003777684656182 0.0084329394760852 2232.303710761984 0.0005159911083178 0.0121441684007788 2353.561564339669 0.0004956505523246 0.0116640890430035 2353.288821791402 +r_0904 phosphomevalonate kinase 0.0052161068064845 0.0014114334713477 27.059136703126423 0.0083102389187687 0.0009838252158585 11.838711563834153 0.0192214647169411 0.0014880689307817 7.7417041453151345 0.0285696742048471 0.0022591287033084 7.907436000530989 0.0405386526931157 0.0046798995841252 11.544289889338064 0.0478763907940958 0.0045750261435385 9.555912773823174 0.0538126793906166 0.0069803570654712 12.971584289275276 0.0634410447110162 0.00982850863125 15.49234990694183 0.071710213490855 0.0095573899925742 13.327794643636192 +r_0905 phosphopantothenate-cysteine ligase 4.31481878771459e-06 3.134799186595541e-08 0.7265193142110924 7.030580687703139e-06 4.356264692394552e-08 0.6196166271178554 1.6327739907715824e-05 4.600913435893524e-08 0.2817850763117142 2.42722233178113e-05 6.601518202962676e-08 0.2719783069117689 3.422437906163664e-05 1.440882688870016e-07 0.4210106153496745 4.056432933484544e-05 1.1858617519527913e-07 0.2923410226171584 4.541354834459573e-05 2.146723121155822e-07 0.472705436903233 5.333381251186711e-05 3.130757436778092e-07 0.5870117453316278 6.0474116457881496e-05 3.044204703130784e-07 0.5033896948706948 +r_0906 phosphopantothenoylcysteine decarboxylase 4.31481878771459e-06 3.134799186595542e-08 0.7265193142110927 7.030580687703139e-06 4.356264692394552e-08 0.6196166271178554 1.6327739907715824e-05 4.600913435893524e-08 0.2817850763117142 2.42722233178113e-05 6.601518202962676e-08 0.2719783069117689 3.422437906163664e-05 1.440882688870016e-07 0.4210106153496745 4.056432933484544e-05 1.1858617519527913e-07 0.2923410226171584 4.541354834459573e-05 2.146723121155822e-07 0.472705436903233 5.333381251186711e-05 3.130757436778092e-07 0.5870117453316278 6.0474116457881496e-05 3.044204703130784e-07 0.5033896948706948 +r_0907 phosphopentomutase -0.0001782602991541 0.0044144139857973 -2476.3865015061983 -0.0001262263508803 0.0081906653002867 -6488.871177183337 0.0001339531373914 0.0050445201735808 3765.884302387733 4.189178341883034e-06 0.0102826073533576 245456.4240092869 1.530105100837514e-05 0.0205142184010544 134070.64906734737 -0.0003252841884662 0.0157649805707757 -4846.525324550745 -2.636163556621297e-05 0.0313144985646965 -118788.1475944215 -3.684952302248868e-05 0.0429732532795094 -116618.20765843704 0.0004002128245096 0.0377446906430196 9431.154708564323 +r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.0023449126491611 0.000282934669138 12.065893765351223 0.003871920472657 0.0010230903499749 26.42333067530268 0.0088619803964999 0.0008362143729859 9.435976334547592 0.0131843147790409 0.0013270928867875 10.06569479740596 0.0186307545079881 0.0024674059468486 13.243725291913142 0.0219395877179189 0.0011162617675378 5.087888532318074 0.0247851287848297 0.0039229086243852 15.827670933008504 0.0292491798032496 0.006141959758171 20.998741843313905 0.0330695281272022 0.0059229817086725 17.910693148961094 +r_0909 phosphoribosyl-AMP cyclohydrolase 0.0012210915771837 9.021931166536272e-06 0.7388414870032893 0.0020758457702125 1.2806641836838752e-05 0.6169360951862737 0.0057321391952357 1.615044921403674e-05 0.2817525650364555 0.0096234216258816 2.605370946226468e-05 0.2707322870713116 0.0103630930236677 4.3633162871352114e-05 0.421043821296408 0.0145089306513367 4.2258876478896095e-05 0.2912611376704218 0.0168020079876638 7.938376625226801e-05 0.4724659475852663 0.0211453987638836 0.0001241312340728 0.5870366194506329 0.0223740152239199 0.0001126447669531 0.5034624577920431 +r_0910 phosphoribosyl-ATP pyrophosphatase 0.0012210915771837 9.021931166536272e-06 0.7388414870032893 0.0020758457702125 1.2806641836838752e-05 0.6169360951862737 0.0057321391952357 1.615044921403674e-05 0.2817525650364555 0.0096234216258816 2.605370946226468e-05 0.2707322870713116 0.0103630930236677 4.3633162871352114e-05 0.421043821296408 0.0145089306513367 4.2258876478896095e-05 0.2912611376704218 0.0168020079876638 7.938376625226801e-05 0.4724659475852663 0.0211453987638836 0.0001241312340728 0.5870366194506329 0.0223740152239199 0.0001126447669531 0.5034624577920431 +r_0911 phosphoribosylaminoimidazole-carboxylase 0.0023449103761948 0.000282934849453 12.065913150685438 0.003871920472657 0.0010230903499749 26.423330675302687 0.0088619804110557 0.0008362143718265 9.435976305966271 0.0131843147706676 0.0013270928874783 10.065694809038217 0.0186307545174119 0.0024674059460797 13.243725281087052 0.0219395861496922 0.0011162618952289 5.087889478009115 0.0247851287629211 0.0039229086262528 15.82767095453449 0.0292491792873163 0.0061419598035818 20.998742368970664 0.0330695281110955 0.0059229817100635 17.91069316189067 +r_0912 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.003566004419056 0.0002834971530417 7.949994439904984 0.00594776624287 0.0010232461697519 17.20387331930809 0.0145941195917144 0.0008366004472539 5.732448894888411 0.0228077364131908 0.001327619928126 5.820919288414068 0.0289938475461872 0.0024684595570266 8.513735726499933 0.0364485186474681 0.001118813452061 3.0695718058731445 0.0415871367804107 0.0039246505214889 9.437174148852613 0.0503945786136427 0.0061443996659696 12.19258070015151 0.0554435433877119 0.0059251960065963 10.686899942815634 +r_0913 phosphoribosylanthranilate isomerase 0.0007737518153022 0.0008148460998492 105.31104208537975 0.0012740322982829 0.0011740986210346 92.15611116115667 0.0032656281543926 0.0010881926658517 33.32261403944658 0.0053687698439837 0.0016457218085825 30.65361072288676 0.0061360165776296 0.0031701864750798 51.66522017944892 0.0082570269352965 0.0029871037225427 36.17650452093957 0.0095591523757171 0.0044449359943102 46.49926917789934 0.0121484645565081 0.0073750348900048 60.70754749046805 0.0129384841067491 0.0075400232207679 58.27593989032178 +r_0914 phosphoribosylglycinamidine synthetase 0.0023449246987237 0.0002829338279505 12.06579589120804 0.0038719214956873 0.0010230903188368 26.423322889588324 0.0088620808138832 0.0008362145096427 9.435870956319278 0.013184467793483 0.0013270928307709 10.065577553512451 0.0186309698676594 0.0024674059717901 13.243572338513806 0.0219398447766617 0.0011162616418557 5.087828347095642 0.0247854151492577 0.0039229085759982 15.827487868871692 0.0292495164920197 0.0061419597400582 20.998500066604496 0.0330699097246007 0.005922981666332 17.91048634743012 +r_0915 phosphoribosylpyrophosphate amidotransferase 0.0023449246987237 0.0002829338279505 12.06579589120804 0.0038719214956873 0.0010230903188368 26.423322889588324 0.0088620808138832 0.0008362145096427 9.435870956319278 0.013184467793483 0.0013270928307709 10.065577553512451 0.0186309698676594 0.0024674059717901 13.243572338513806 0.0219398447766617 0.0011162616418557 5.087828347095642 0.0247854151492577 0.0039229085759982 15.827487868871692 0.0292495164920197 0.0061419597400582 20.998500066604496 0.0330699097246007 0.005922981666332 17.91048634743012 +r_0916 phosphoribosylpyrophosphate synthetase 0.0070500989083653 0.0022674983913777 32.16264652240854 0.0117482998490593 0.0047892096878334 40.76512984316573 0.0279324819319874 0.0044568216126732 15.955694963036755 0.0431819213725887 0.0070127093816376 16.23991975977518 0.0567477696500051 0.014179483587609 24.986856179655565 0.0695904631401555 0.0098814564019645 14.199440492389392 0.0797256847032756 0.0205301049100935 25.750929561160703 0.0967451609602268 0.0295849549584204 30.580294316305125 0.1066807394291589 0.0283546407170595 26.578969051755024 +r_0917 phosphoserine phosphatase (L-serine) 0.0168497005132839 0.0046771250049767 27.757911787746 0.0305004791312658 0.007303706248713 23.94620168843864 0.077570532426074 0.0076087006205993 9.808751316552504 0.116998821136761 0.010391467136877 8.881685333162787 0.1427884942710252 0.0205731952666589 14.40816038553446 0.1709403570406382 0.0170743708011878 9.988496044341762 0.2061999485483082 0.030917679493204 14.994028713814508 0.2497672908331568 0.0460181045641354 18.424391925232243 0.2722865685471959 0.0460517981804792 16.912989291462996 +r_0918 phosphoserine transaminase 0.0168496999524839 0.0046771249980354 27.75791267040333 0.0305004786678659 0.0073037062592908 23.946202086938754 0.077570531862674 0.0076087006195579 9.808751386451688 0.1169988206783611 0.0103914671498585 8.881685379056508 0.1427884936032249 0.0205731952537248 14.408160443860975 0.1709403565298379 0.0170743707902167 9.98849606777111 0.2061999479487082 0.0309176795084094 14.994028764789077 0.2497672902713572 0.0460181045601577 18.424391965081497 0.272286568050596 0.0460517981755045 16.9129893204821 +r_0919 phytoceramidase 3.612326381011889e-10 3.526219654191404e-09 976.163082252727 3.454220880145038e-10 3.417513028855332e-09 989.3730445841774 1.5223281407559455e-10 3.8871367674730565e-09 2553.4158263295403 3.2695018682151467e-10 3.1836910662173872e-09 973.7541663970344 4.609697464102258e-10 3.347725763233716e-09 726.2354610696099 5.411301076197309e-10 3.620449583793559e-09 669.0534370225364 3.4862532126951353e-10 4.1373700282464764e-09 1186.7669316675876 2.454720793857214e-10 3.638244659135848e-09 1482.141947972384 4.130494063939707e-10 3.088214211572061e-09 747.6621836920137 +r_0920 phytoceramidase 2.6130949275322176e-10 3.4652484590119393e-09 1326.1089072965624 -1.6985322066067043e-10 3.41507709400553e-09 -2010.6048508954127 1.1833866456156548e-10 3.6169142287965036e-09 3056.409536305701 -1.3654956630529296e-10 3.0186114842758837e-09 -2210.634252420087 -5.162506122487258e-11 3.281551084100305e-09 -6356.507878617831 3.3857324467643045e-10 2.7149556027269834e-09 801.8813197485897 1.5810160776579022e-10 3.014933084410393e-09 1906.9591555809336 1.3596441616243643e-10 2.854641417375457e-09 2099.5503808621684 3.0581904408704254e-11 3.370190597870278e-09 11020.211667756868 +r_0921 Phytosphingosine phosphate lyase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0922 phytosphingosine synthesis -1.9474177133520022e-10 2.79144913798604e-09 -1433.410571777765 7.8377060129303e-11 2.323639429677736e-09 2964.6932735730315 5.3677825663322544e-11 2.1281975288622554e-09 3964.761058338525 8.989824110637595e-13 2.792719724814111e-09 310653.43330905726 -3.9158345892990926e-11 2.389798064120154e-09 -6102.908612766281 3.3293243668424536e-11 2.178432727353418e-09 6543.167583936719 5.2136250652630543e-11 2.0885273760578887e-09 4005.902514880041 1.8174987281646543e-11 2.5642681534012952e-09 14108.775503742678 -3.174576768450246e-11 2.1910327199751434e-09 -6901.810476754527 +r_0929 polyamine oxidase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0935 porphobilinogen synthase 5.583300514552437e-05 0.0005758574357774 1031.3925146542083 3.202359370538132e-05 0.0004240184347016 1324.0813588962028 5.76790150802388e-05 0.0006714193820664 1164.0618015623809 5.572225737017745e-05 0.0008123740338252 1457.8986425987962 0.0001812911626208 0.0020520646625099 1131.916543996973 0.0001543518485768 0.0018645205691326 1207.9677608816532 0.00016242695639 0.0023298779443293 1434.4158113350682 0.000373878679773 0.0044751780504881 1196.9599478644732 0.0003706533578795 0.0043256935473029 1167.045557620077 +r_0936 poylamine oxidase 2.642000000000035e-10 4.409503911433593e-10 166.9002237484306 2.1659999999999998e-10 4.1196891105606757e-10 190.1980198781476 1.6839999999999866e-10 3.7425853883483666e-10 222.2437879066744 2.43800000000002e-10 4.294163942933967e-10 176.1346982335493 8.420000000000068e-11 2.777152951441893e-10 329.8281415014099 2.3680000000000145e-10 4.2516104287961655e-10 179.54435932416132 1.1080000000000043e-10 3.13915703037819e-10 283.317421514276 1.0380000000000068e-10 3.0568652055622655e-10 294.49568454356904 3.850000000000126e-10 4.86643981235644e-10 126.40103408717611 +r_0937 poylamine oxidase 6.851180783318917e-05 0.0006796917165719 992.0796692839218 0.0001082613168275 0.0011640808056755 1075.2509204466098 9.915181737949489e-05 0.0009605998730438 968.8172122627184 0.0001429418516476 0.0013500434153298 944.4703561401376 0.0003189564263946 0.0030179632215315 946.199220892002 0.0002784897649764 0.0026016288563381 934.191910628312 0.0003697076167596 0.0039439112813472 1066.764952238273 0.0006302499028852 0.0065214492002466 1034.740215014942 0.0006483568420369 0.0064686996324794 997.7066968486316 +r_0938 prephenate dehydratase 0.0025849646080516 0.0014399658353037 55.70543715834722 0.0041752667895405 0.0005500939772998 13.175061739237334 0.0115408203893431 0.0013105161740319 11.355485397226422 0.0192917009442174 0.0014005742829647 7.259983383604136 0.0208856642557827 0.0031694872758517 15.175420025121614 0.0292552781770722 0.0037244375028376 12.73082238457913 0.0338379917414459 0.0047690981969198 14.093916191481442 0.0427125553617883 0.0074941610761729 17.545569476457544 0.0449275154523642 0.0053595694096835 11.929369687416084 +r_0939 prephenate dehydrogenase (NADP) 0.0018980298288668 0.0010562464592533 55.6496237935306 0.0031900322942998 0.0013140822802357 41.19338486271399 0.0087001232915405 0.0021512564910269 24.72673569027082 0.0144961455197185 0.0028758942024489 19.83902685397972 0.015895702701535 0.0057123253042406 35.936286753079706 0.0219056177190135 0.0048814010572007 22.28378637760944 0.0257990766937269 0.0090081767374935 34.916663276108345 0.0327191241697299 0.0135581892398582 41.43811787114269 0.0344136375913697 0.0127515020052051 37.05363018178284 +r_0940 proline oxidase (NAD) 0.0001680507053807 0.0024222486204127 1441.379621064055 0.0004968622000998 0.0055607508183232 1119.1736495966668 0.0002805427351237 0.0039228650640689 1398.3128318537651 0.0005099235750886 0.0063807384834838 1251.3127055117031 0.0010119699383173 0.0127639652374202 1261.2988542568055 0.0005062499639358 0.0081084589376008 1601.6710153540278 0.0014673055883586 0.0188477755315544 1284.5160327262074 0.0021254445713791 0.0277662492310807 1306.3737161145286 0.0020585012177548 0.0268991036437994 1306.732462035534 +r_0941 prolyl-tRNA synthetase 0.0026275687658877 1.9413951099747325e-05 0.7388560616105464 0.0044668440894813 2.7557799076835927e-05 0.6169411451304083 0.0123345215649586 3.475320556436696e-05 0.2817556026096549 0.0207078524190692 5.606322808845838e-05 0.2707341493163797 0.022299490576542 9.3891012924517e-05 0.4210455508041318 0.0312205778189143 9.093380960993e-05 0.2912624171703817 0.0361548625881259 0.0001708198316701 0.4724671024644823 0.0455010482308676 0.0002671082064777 0.5870374790542267 0.0481448071317917 0.0002423914317861 0.5034632938140821 +r_0942 protoporphyrinogen oxidase 6.979150013848696e-06 7.198215357287375e-05 1031.3885420150002 4.002935212584061e-06 5.300230081199174e-05 1324.0859018993854 7.210479948339399e-06 8.392734479199442e-05 1163.9633615696166 6.964870130608052e-06 0.000101546770379 1457.9851235533924 2.2660994245275028e-05 0.0002565080937637 1131.9366263782815 1.929343153149557e-05 0.0002330650945338 1208.0022890349371 2.030294510930716e-05 0.0002912347490477 1434.4458278333525 4.673442750605045e-05 0.0005593972725786 1196.970418662359 4.6331266381937634e-05 0.0005407117060878 1167.055745099601 +r_0943 purine-nucleoside phosphorylase 1.4693703999999929e-10 5.850691734073873e-10 398.1767792568776 1.0890673735364179e-10 9.896807750244087e-10 908.741551783632 2.5248440000007077e-10 4.606570150706756e-10 182.4496939496248 7.699720000000051e-11 3.368557031506334e-10 437.4908479147698 1.7805499996011902e-10 4.376298044236709e-10 245.783496403747 1.0549760000000059e-10 3.4801337309910727e-10 329.8780001621888 1.8119999999999827e-10 4.1085316119509276e-10 226.74015518493195 2.5240000000000256e-10 4.5468185263700976e-10 180.1433647531716 1.5259999999998694e-10 3.817622145755563e-10 250.17183130772543 +r_0949 guanosine phosphorylase 4.0249119836922e-05 0.0011483890275044 2853.202833148551 0.0001299302902966 0.0028562743824966 2198.312938403718 3.6238160303699007e-05 0.0011700912413025 3228.892503086224 0.0001284141781516 0.0032899271393459 2561.9656541822 0.0001422951748708 0.0044032914208031 3094.476973515234 0.0001669502499144 0.0046738403966109 2799.540820697613 0.0006432171165342 0.0129934061124702 2020.0653525017783 0.0005823578582623 0.0140518267790253 2412.919578513695 0.0005945948713333 0.0143021751323862 2405.364698204345 +r_0950 guanosine phosphorylase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0951 inosine phosphorylase -6.520205648618626e-06 0.0011405424880809 -17492.431213770196 3.551105320933462e-05 0.0026538451160284 7473.293175463591 9.058649697586282e-05 0.0031393717105431 3465.606702265672 3.063226744607297e-05 0.0035921273791514 11726.612747408471 0.0002388259056861 0.0099375166816757 4160.987750941406 7.942431113243182e-05 0.0059827234500877 7532.609807735301 -0.0002576815269056 0.0113913574045097 -4420.711698390742 0.0001939083714227 0.0129230973026023 6664.538105180936 7.613701856873861e-06 0.0149901536611099 196883.90671058965 +r_0953 pyridoxal oxidase 2.836000000000049e-10 5.028136874836154e-10 177.29678684189233 6.636000000000335e-10 4.75899502066559e-10 71.7148134518588 1.7819999999999828e-10 4.0654374372643536e-10 228.1390256601792 1.7919999999999818e-10 4.1559824877021735e-10 231.9186656083826 7.120000000000041e-11 3.443171079893901e-10 483.5914438053204 7.200000000000041e-11 2.8780647406425077e-10 399.7312139781238 1.3559999999455385e-10 3.894136214953122e-10 287.1781869549796 5.460000000000015e-11 4.6310013209507736e-10 848.1687401008719 1.3619999998910787e-10 4.459701087675311e-10 327.4376716616711 +r_0954 pyridoxamine 5'-phosphate oxidase 8.94999999999784e-10 3.4928412486102955e-10 39.02615920235909 9.45399999999978e-10 2.44194115721956e-10 25.82971395408945 9.42199999999979e-10 2.850884337938161e-10 30.257740797476384 9.327999999999815e-10 2.7184359434785753e-10 29.142752395782896 8.873999999999976e-10 3.6214288546634425e-10 40.809430410902095 9.583999999999724e-10 2.6661518473512944e-10 27.81877970942582 9.073999999943343e-10 3.299197014438923e-10 36.3587945168561 8.307999999887043e-10 4.164205100669623e-10 50.12283462597785 9.033999999943363e-10 3.5901841017234806e-10 39.74080254312584 +r_0955 pyridoxine 5'-phosphate oxidase 1.6580000000010395e-10 6.72904837390688e-10 405.8533398011256 -2.6360000000000326e-10 6.598500742017701e-10 -250.3224864194847 3.3580000000000917e-10 5.705291059114826e-10 169.90146096231894 1.4e-11 5.454021385166709e-10 3895.729560833364 1.8499999999999804e-10 5.095359902745366e-10 275.4248596078605 2.472000000000022e-10 4.742753919712531e-10 191.8589773346475 2.6640000000000365e-10 5.38784834437241e-10 202.2465594734361 3.230000000000082e-10 5.14124367028995e-10 159.17163065912757 2.7220000000000424e-10 4.867797766035139e-10 178.83165929592445 +r_0956 pyridoxine oxidase 6.461862111569326e-05 0.0015296336425437 2367.171592543084 0.0001596387552819 0.0031957727077015 2001.877740813652 7.739210897490509e-05 0.0019297624235583 2493.487319468364 0.0001991419264358 0.0039869706368712 2002.0749564030853 0.0003920853946315 0.0078970835719765 2014.1233721287304 0.0002085098950431 0.005308166503575 2545.762397739825 0.0003830467291373 0.0088931899808841 2321.6984520171018 0.0008948975774447 0.0180236806897743 2014.0495565133444 0.0007340217406304 0.01587612930492 2162.896332101006 +r_0957 pyrroline-5-carboxylate reductase 0.0027956193866688 0.0024220367635364 86.63685675833281 0.0049637062207814 0.005560300210681 112.01912368225604 0.0126150641521117 0.0039224982498088 31.09376379312534 0.0212177758235923 0.0063800369082296 30.069301142938546 0.0233114604354622 0.0127627010728458 54.7486122037675 0.031726827728846 0.0081076820032406 25.554657000482567 0.037622168027117 0.0188455640283182 50.09164813344855 0.0476264925462513 0.0277630653445741 58.29332344306633 0.0502033082489496 0.0268961408085311 53.57443910898815 +r_0958 pyruvate carboxylase 0.0401767890329018 0.0206302246383496 51.34861479710335 0.0699656945639486 0.0445884552702339 63.72902541470533 0.18153245160752 0.041550615247585 22.888808518610805 0.5498923053288702 0.1111477056653766 20.21263156226624 0.3457483340774634 0.131858284424452 38.13707006753349 0.4452449756946575 0.0943158451653622 21.18291060291327 0.5391308713060445 0.1861953076761127 34.53619846050638 0.6691245101217367 0.2384249054358601 35.6323676429791 0.7821467680863766 0.3132280291146646 40.04721899970482 +r_0959 pyruvate decarboxylase 0.0575343644625446 0.0190862870582493 33.1737166761869 0.0013294148622535 0.0095381131520702 717.4670167220365 0.2052079375624635 0.0402034886514884 19.59158555416546 0.0039885134550177 0.0252790760974433 633.7969366918084 0.2009987728922353 0.0936544926006743 46.59455938613458 0.5116113780832408 0.073353802054415 14.337797241577398 0.2177733704073986 0.1111346317529161 51.03224124465332 2.552239183188033 0.2311930984737915 9.0584417007894 5.659343965826297 0.2285948135785001 4.039245802320198 +r_0960 pyruvate decarboxylase (acetoin-forming) 0.0014392004391738 0.0060909457051038 423.2173322987658 5.002183239840678e-05 0.0010287383709091 2056.578740889801 0.0001507234151827 0.003075372935099 2040.4082082198115 0.0001112793613985 0.0024125649683305 2168.025533226134 0.0003586770242873 0.008041702505101 2242.0456178030745 0.0008945790632098 0.0104145974248141 1164.1897125834043 0.0004599194070073 0.0109878873227854 2389.089730803439 0.0013432174085089 0.017869196490693 1330.3279407708392 0.0006664504311681 0.016644353452676 2497.463078161892 +r_0961 pyruvate dehydrogenase 0.3373382673341216 0.0421353498890537 12.490533677674971 0.6230043196500415 0.0841802582831225 13.511986294157465 1.033248283606257 0.1164587317296376 11.27112752833925 1.6675365633096388 0.2045711760783084 12.267867498646403 2.4771614139187745 0.3729288520403383 15.054685170894016 2.422516669873273 0.268845144961981 11.097762434635582 3.436177962702028 0.4148807317444449 12.073901184623296 3.9562532535285646 0.5776946232008099 14.602063775506954 4.3372378907576365 0.557006912893684 12.842433985016788 +r_0962 pyruvate kinase 0.5070461126708602 0.0480961549881428 9.48555837156445 0.7309752212419143 0.0813509432088208 11.129097244993751 1.737812487066534 0.1319266063802354 7.591532881831831 2.4158977714541563 0.1808262753954354 7.4848479737863265 3.4230483536505365 0.3689309959614049 10.777849385853855 4.165665083222391 0.2812480632577157 6.751576462314955 4.732928483200475 0.4403441598210973 9.30384140356438 8.282904174366502 0.7353455039826964 8.877870472755259 11.960204551012827 0.6315252479809782 5.280221130728894 +r_0963 quinone oxidoreductase -3.573787597845846e-10 2.9275360457156436e-10 -81.91690092271459 -3.4303333333472275e-10 5.726070188001368e-11 -16.692459978558475 -3.1193333333335736e-10 2.2970351292890388e-10 -73.63865556600328 -3.4893333332778447e-10 6.334822929933154e-11 -18.154823070406646 -3.4286666666670365e-10 9.871371621230294e-11 -28.79070082022913 -2.9193333326997896e-10 2.3654341273915874e-10 -81.02651728379513 -2.766333333443469e-10 1.9179914449250677e-10 -69.33334539759154 -2.6873333333604863e-10 3.2636606690790473e-10 -121.44606806174912 -3.3896666667221235e-10 1.4937073598176647e-10 -44.066496994588256 +r_0964 reduced glutathione via ABC system 4.4293320414223593e-05 0.0018078953936525 4081.643409763472 8.062904742063384e-05 0.0032910085461389 4081.666163026941 2.270815311215336e-05 0.0016057089053825 7071.067811865326 0.0001006364340592 0.0041076432766728 4081.666163027078 -2e-13 1.4142135623730835e-11 -7071.067811865417 0.0002434393240419 0.0079136421191729 3250.765729947409 0.0003020082322286 0.0123269678244325 4081.6661630274807 0.0004554830264894 0.0185918965688981 4081.797890954007 0.0002935552521231 0.0146762944628578 4999.499874967782 +r_0965 riboflavin kinase 4.429308950402356e-05 0.0018078968194948 4081.667907429802 2.687632253066774e-05 0.0019004446134804 7071.073846922051 6.812433161143406e-05 0.0027806113057648 4081.671320644829 0.0001004890083776 0.0041016375502656 4081.677803856919 0.0002678951215527 0.009468685403845 3534.474741072131 0.0002736039527179 0.0086486591113542 3161.0139493376573 0.0003020080586638 0.0123269716604911 4081.6697789551567 0.0007639553275948 0.0241487410004378 3161.0148038978045 0.0007338871595801 0.023198286185282 3161.01540713065 +r_0966 riboflavin kinase 2.287029355850858e-09 2.7140586571019663e-08 1186.7178924304792 2.5705536745057248e-09 3.393263793376389e-08 1320.0517176630665 7.95681361244052e-09 9.01595907411666e-08 1133.1117597149891 9.888210866216835e-09 1.196707348014877e-07 1210.2364767558088 1.8176140304139973e-08 1.969069800326824e-07 1083.3266949850345 1.9959787421283493e-08 2.201257841797888e-07 1102.846335653177 1.6203073999159968e-08 2.3369561461646455e-07 1442.291843069903 2.6447369338843983e-08 3.2200168177323045e-07 1217.5187545034871 3.5354371220382855e-08 3.719410148419338e-07 1052.0368542928536 +r_0967 riboflavin synthase 4.543121265431256e-05 3.355797913054428e-07 0.738654708292467 7.401504379065325e-05 4.566688662576916e-07 0.6169946579364999 0.0001718799276096 4.842374291644184e-07 0.2817300634802316 0.0002555047405979 6.916769263603523e-07 0.2707100168637339 0.0003602664763946 1.5168500154262989e-06 0.4210355708380148 0.0004270003661968 1.2436171809886648e-06 0.2912449916764805 0.0004780455503919 2.2585061251396865e-06 0.4724458000472563 0.0005614189923658 3.2956017913570863e-06 0.5870128791812804 0.0006365790537736 3.204861628702823e-06 0.5034506884422627 +r_0968 riboflavin synthase 2.27159689193862e-05 1.67704483629235e-07 0.7382669179746634 3.700793918492328e-05 2.2824513697837306e-07 0.6167464117303731 8.59401091359336e-05 2.420891088617849e-07 0.2816951378068028 0.0001277526129829 3.45791829923098e-07 0.2706729998307705 0.0001801336506292 7.58346451400436e-07 0.4209909968245084 0.0002134990061805 6.220977683541156e-07 0.2913820441056685 0.0002390228938999 1.1292290632494963e-06 0.4724355248255957 0.0002807094566406 1.6478097608643272e-06 0.587016120006945 0.0003182896928869 1.6023966381414358e-06 0.5034396884194597 +r_0969 ribokinase 0.0002017056425665 0.0037802546608294 1874.144229545493 0.0003342845045852 0.0066016170431263 1974.849851720656 6.179825251691839e-05 0.0023666740859125 3829.678007909168 0.000351167457055 0.0075272307735262 2143.48756477902 0.0006786522984698 0.0149751850589613 2206.606401057798 0.0005736436111063 0.0122949594940518 2143.309758185761 0.0011417780594044 0.0236467209536127 2071.043558670922 0.0013582887079716 0.0314597152183815 2316.128745954215 0.0009137082769563 0.0255126725835527 2792.212046993592 +r_0970 ribonucleoside-triphosphate reductase (ATP) 4.083200965311832e-05 3.933145457025028e-05 96.32505209609874 8.037823724680258e-05 6.200543917298182e-05 77.14207389569044 8.349266873826678e-05 0.0001337689720375 160.21642865061688 0.0003090715488563 0.0002031320616081 65.72331305157037 0.0004697396270295 0.000269220651861 57.31274015851168 0.0001349681023678 0.0002857859212987 211.74330548097285 8.82510141666309e-05 0.0002557918516842 289.84579282141493 0.0003875928343401 0.0004761546148021 122.84917898773476 0.000941364605301 0.0003896245712213 41.38933724799783 +r_0971 ribonucleoside-triphosphate reductase (CTP) 1.0356992993145738e-06 7.133607300737152e-05 6887.72050483975 4e-13 1.999799949986896e-11 4999.49987496724 8.370348091792262e-06 0.0002922927152817 3492.001910509963 9.17318065931423e-06 0.000368320447374 4015.187981718195 6.020491950007208e-06 0.000425713025958 7071.067107024605 1.5834250606838688e-05 0.000542261292411 3424.6097644611154 1.889344226964844e-05 0.0009022685416512 4775.564604766287 1.3601317164437851e-05 0.0009617583175693 7071.067499874243 1.3497392699221777e-05 0.0009278186200843 6874.058129299297 +r_0972 ribonucleoside-triphosphate reductase (GTP) 4.4190450482748566e-08 1.5532683191013703e-06 3514.9411289838467 7.211557452974466e-08 2.527721770029325e-06 3505.098290504148 4.151575999979078e-07 9.26276610033926e-06 2231.1445341205217 3.089613642441575e-07 9.738832349801354e-06 3152.11980424362 1.0421933841195164e-06 2.124508430727517e-05 2038.49732986204 7.200155570146446e-07 1.9222963022876253e-05 2669.798289161865 6.93239867520686e-07 1.9982778525930788e-05 2882.520100495304 5.425189551926983e-07 1.9161516392342883e-05 3531.953346318908 6.147370702386219e-07 2.1709143651361217e-05 3531.451851916853 +r_0973 ribonucleoside-triphosphate reductase (UTP) 5.536494961007007e-07 9.470452801657649e-06 1710.5502431334482 8.884109430390683e-07 1.399852821093567e-05 1575.681650548971 5.948958214466694e-06 0.0002171980156197 3651.0260753140574 3.6467105874012905e-06 5.192547956040537e-05 1423.8991089613278 2.2289114313622512e-05 0.0008090886075324 3629.971995064639 1.6706556601422842e-05 0.0005135555453887 3073.9760301353404 1.3339902838959056e-05 0.0006994874949971 5243.572636483654 6.969578126024158e-05 0.0021149102810456 3034.488232721957 6.453406046179786e-05 0.002024484008892 3137.0783031550764 +r_0974 ribonucleotide reductase 4.094533462548814e-05 3.931656778791967e-05 96.02209420812848 5.285027973848765e-05 6.200957976444882e-05 117.33065571513146 0.000225892875257 0.0001337560904868 59.21217760174156 0.0001508391039793 0.000203177779221 134.698346689266 0.0001787417815746 0.0002693099606491 150.669842426729 0.0006336346717829 0.000285707224128 45.09021315455214 0.0007722328372888 0.000255659922772 33.106585271569216 0.0006229625144322 0.0004763245562004 76.4611907081698 0.0002044793281109 0.000389862391127 190.6610290285918 +r_0975 ribonucleotide reductase 4.3949649369221575e-10 1.0119840616742472e-09 230.2598715117284 4.6180000000002047e-10 7.999179543845046e-10 173.21740025648967 7.370000000000416e-10 6.737371775083168e-10 91.41617062527524 5.8760000000003e-10 7.22239964356161e-10 122.91354056435064 6.425233843900385e-10 7.43676291813839e-10 115.74307019499796 3.795000000000152e-10 8.433694353015601e-10 222.23173525731923 4.69300000000025e-10 9.41692554379258e-10 200.65897174072188 6.143000000000324e-10 7.18045003969462e-10 116.8883288245847 6.321229859675381e-10 7.265834753191986e-10 114.94337200965371 +r_0976 ribonucleotide reductase 0.0001476084848971 0.0002500261917393 169.38470164064003 0.000244798853859 0.000443834362568 181.3057355340677 0.0005312523098229 0.0004355506542974 81.98564904923703 0.0007852092342102 0.0006200877879949 78.97102593535571 0.0011654043542331 0.001724310166555 147.95810229229153 0.0013166892179509 0.0009276432705266 70.45271259760526 0.0014742121799862 0.001627166572199 110.37533092517036 0.0018671631591585 0.0035880296758624 192.1647638698847 0.0020628575853594 0.0034373117404742 166.62864973664006 +r_0977 ribonucleotide reductase 6.351830073661085e-10 6.042677714280681e-10 95.13286161948264 5.032296732760513e-10 6.324306261773904e-10 125.67435104933983 7.272055395166702e-10 5.291769669780104e-10 72.76855554891982 4.5840000000001824e-10 6.002845227903621e-10 130.95212102756065 5.09000000000022e-10 6.48384978709495e-10 127.38408226119196 5.10000000000022e-10 6.062784135221655e-10 118.87812029845873 4.874209602121212e-10 6.328938597198691e-10 129.84543369748388 6.820000000000353e-10 5.6686882790785e-10 83.1185964674224 4.236000000000157e-10 6.342266855768157e-10 149.72301359225503 +r_0978 ribonucleotide reductase 5.4473548909395e-05 1.5930976475330242e-06 2.924534346353674 8.874661616769917e-05 2.570248503746613e-06 2.896165076186982 0.0002058415101952 9.23362436069467e-06 4.485793148299004 0.0003062978032317 9.72698260679594e-06 3.1756618898884788 0.0004312783794352 2.12329192062858e-05 4.923251481812808 0.0005116814349479 1.921835730354321e-05 3.755922335837032 0.0005729621399938 2.003740605035116e-05 3.4971605716505683 0.0006731606170316 1.945389222872977e-05 2.8899332100729933 0.0007632808199901 2.1937926305058936e-05 2.8741618720801667 +r_0979 ribonucleotide reductase 5.838000000000281e-10 6.208499423614308e-10 106.34634161723204 5.608000000000274e-10 6.843953823689152e-10 122.03911953796045 8.684000000000046e-10 4.3164650321849325e-10 49.705953848283166 7.572000000000407e-10 4.893833458668461e-10 64.6306584610169 7.179997971161677e-10 6.521939124844507e-10 90.83483241972696 6.114000000000304e-10 6.158456731833505e-10 100.72713005942424 8.006000000000275e-10 4.665652972900033e-10 58.27695444541436 7.59200000000041e-10 5.032554154727474e-10 66.28759424034777 7.472000000000402e-10 5.759848189859993e-10 77.08576271225483 +r_0982 ribose-5-phosphate isomerase 0.0570040104301087 0.0407380279537406 71.46519630173842 0.1142992346472313 0.0799269053571451 69.9277695111681 0.2452231747060351 0.1043241192668069 42.54252045789188 0.4087850399739969 0.1812761479297449 44.34510322131063 0.5798747743326658 0.3112700056649068 53.678831955248285 0.5439236242290965 0.2617626370690494 48.12488838668221 0.7353530448861457 0.369986410776063 50.31411963941046 0.8969150796239 0.541892275847379 60.41734475850362 1.1018351020683714 0.413655890618144 37.542449849494425 +r_0983 ribosylnicotinamide kinase -1.4693703999999929e-10 5.850691734073873e-10 -398.1767792568776 -1.0890673735364179e-10 9.896807750244087e-10 -908.741551783632 -2.5248440000007077e-10 4.606570150706756e-10 -182.4496939496248 -7.699720000000051e-11 3.368557031506334e-10 -437.4908479147698 -1.7805499996011902e-10 4.376298044236709e-10 -245.783496403747 -1.0549760000000059e-10 3.4801337309910727e-10 -329.8780001621888 -1.8119999999999827e-10 4.1085316119509276e-10 -226.74015518493195 -2.5240000000000256e-10 4.5468185263700976e-10 -180.1433647531716 -1.5259999999998694e-10 3.817622145755563e-10 -250.17183130772543 +r_0984 ribulose 5-phosphate 3-epimerase 0.0947670300438015 0.0815412752381049 86.0439281471799 0.1969714087656979 0.1599569918340349 81.2082285629116 0.411536430059068 0.2087695470226994 50.72929922455095 0.6928646163071468 0.362447657606837 52.31146880304305 1.004883099475273 0.6227058018775359 61.96798435586175 0.8898932240493969 0.5240738139609474 58.89176361813232 1.244470752811835 0.7405265285742096 59.50533806447582 1.5159357413425447 1.082565226031974 71.4123426546584 1.901009060632148 0.8275780610950917 43.53362002493007 +r_0985 S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase -1.8227875978454501e-10 3.898229804960534e-10 -213.86089139339512 -3.09133333334715e-10 9.918946482501672e-11 -32.08630520527498 -1.6853333333332819e-10 3.399635070832493e-10 -201.7188530952886 -2.9853333332777314e-10 1.1639254701297035e-10 -38.988124279300415 -3.0246666666669446e-10 1.81990493332727e-10 -60.16877672450196 -9.993333326168443e-11 2.5158031332542954e-10 -251.74814560287285 -1.7813333334432568e-10 2.0936293292285907e-10 -117.53158658866369 -7.293333333603679e-11 4.94207130805521e-10 -677.6148959605144 -2.1346666667218435e-10 1.9389444754931803e-10 -90.83125275342267 +r_0986 S-adenosyl-methionine delta-24-sterol-c-methyltransferase 2.37563506458969e-06 6.341000410975288e-05 2669.1811825359127 3.68705043852249e-06 9.086875230121211e-05 2464.5378146122107 6.5206916062218095e-06 0.0001517239307435 2326.807337411193 9.11949746576427e-06 0.0002204568514647 2417.4232439054967 1.524423062517026e-05 0.0003284643726706 2154.679896592115 1.9894409134220148e-05 0.000421050201183 2116.4247620646506 2.478713005794822e-05 0.0005094648587247 2055.36041297926 3.076708167743874e-05 0.0007009558689561 2278.265700676295 2.544335421922833e-05 0.0006701601338576 2633.929976697749 +r_0987 S-formylglutathione hydralase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_0988 saccharopine dehydrogenase (NAD, L-lysine forming) 0.004813227326796 3.556267182060622e-05 0.7388529443149939 0.0081824453907497 5.0480787401053e-05 0.616940107637278 0.022594599529601 6.366143382880475e-05 0.2817550881811481 0.0379330186829625 0.000102697486902 0.2707337577333328 0.0408486101048924 0.0001719910494753 0.4210450466582642 0.0571904195277281 0.0001665740336442 0.2912621292513366 0.0662291318641015 0.0003129107419644 0.472466923779927 0.0833496440291107 0.0004892934691728 0.5870372631728625 0.0881925296371844 0.0004440169180408 0.5034631843166931 +r_0989 saccharopine dehydrogenase (NADP, L-glutamate forming) 0.004813227326796 3.556267182060622e-05 0.7388529443149939 0.0081824453907497 5.0480787401053e-05 0.616940107637278 0.022594599529601 6.366143382880475e-05 0.2817550881811481 0.0379330186829625 0.000102697486902 0.2707337577333328 0.0408486101048924 0.0001719910494753 0.4210450466582642 0.0571904195277281 0.0001665740336442 0.2912621292513366 0.0662291318641015 0.0003129107419644 0.472466923779927 0.0833496440291107 0.0004892934691728 0.5870372631728625 0.0881925296371844 0.0004440169180408 0.5034631843166931 +r_0990 sedoheptulose 1,7-bisphosphate D-glyceraldehyde-3-phosphate-lyase -0.0001838579425873 0.0036183831809864 -1968.0320197575777 -0.0003344701769482 0.0061099333098707 -1826.7498064005945 -0.0001809562983882 0.0044760514215833 -2473.553814623208 -0.0002683646336092 0.0067044011124006 -2498.243163502133 -0.0006563450102389 0.0134091171622315 -2042.998263573228 -0.0004384791484775 0.0109365909347406 -2494.210037743614 -0.0011167892171054 0.0215036923237871 -1925.4924738190089 -0.0012120680360782 0.030280845095086 -2498.2793204464974 -0.0007093652827523 0.0224264766168959 -3161.4849446648923 +r_0992 serine O-acetyltransferase 2.196885348476013e-05 0.0007141577466257 3250.773860917074 6.207609525749133e-05 0.0016585685626505 2671.8313318045803 3.437770600210604e-05 0.0010949749040941 3185.130805490858 5.589046058191445e-05 0.0017667096686686 3161.0218457214487 0.0001500002409445 0.0040152678520523 2676.840934900457 0.0001741381266839 0.0039241173391918 2253.4509896927143 0.0001910088901902 0.005526552306359 2893.348210574652 0.0002991874015567 0.0086423560931027 2888.609629996158 0.0001889364318791 0.0066907582380382 3541.2747935863936 +r_0993 serine palmitotransferase -1.9469628306220782e-10 1.6315599867639483e-09 -838.0026372884813 -2.860679584993173e-10 2.3729727480216482e-09 -829.5136444046427 -2.5970333427871677e-10 1.7655281247457551e-09 -679.8249740032096 -3.565839694956145e-10 2.372366450292009e-09 -665.3037301838621 -3.444606466973953e-10 2.127516978119177e-09 -617.6371665434909 -2.1608373516605822e-10 2.019144946076345e-09 -934.4270842618728 -2.53567309746474e-10 1.7687947082476455e-09 -697.5641734008032 -2.1988151777847176e-10 1.77847019372856e-09 -808.8311431069661 -1.8896275510042327e-10 1.549206181510308e-09 -819.8473718733569 +r_0995 seryl-tRNA synthetase 0.0040581615091322 2.9983972300170885e-05 0.7388560616105795 0.0068988393326027 4.256177837926915e-05 0.6169411451304502 0.0190501125216275 5.367475933312989e-05 0.2817556026096595 0.0319823445592932 8.658712847403381e-05 0.2707341493163726 0.0344405579430781 0.0001450104368914 0.4210455508041094 0.0482187750297622 0.0001404431696816 0.2912624171704249 0.0558395554201756 0.0002638235295227 0.4724671024643907 0.070274317822967 0.0004125365837704 0.5870374790541445 0.0743574842658118 0.0003743626394819 0.5034632938141098 +r_0996 shikimate dehydrogenase 0.0052205259442072 0.0018452916334718 35.34685304110687 0.0085911211558188 0.0015329995362894 17.843998571142254 0.0234777578226843 0.0026533896684269 11.301716665052377 0.0391133977095598 0.0034503658296924 8.821442349021886 0.0428365307734951 0.0069640715401313 16.257319195513272 0.0593364683675767 0.006629716167228 11.173088573722188 0.0691322083053571 0.0108932693696886 15.757155219999646 0.0873769259750843 0.0165973939258096 18.99516804990648 0.0920948624104587 0.0151617995402076 16.463241426685546 +r_0997 shikimate kinase 0.0052205259442072 0.0018452916334718 35.34685304110687 0.0085911211558188 0.0015329995362894 17.843998571142254 0.0234777578226843 0.0026533896684269 11.301716665052377 0.0391133977095598 0.0034503658296924 8.821442349021886 0.0428365307734951 0.0069640715401313 16.257319195513272 0.0593364683675767 0.006629716167228 11.173088573722188 0.0691322083053571 0.0108932693696886 15.757155219999646 0.0873769259750843 0.0165973939258096 18.99516804990648 0.0920948624104587 0.0151617995402077 16.46324142668555 +r_0998 sirohydrochlorin dehydrogenase 2.2801938289599544e-11 7.649326913700785e-10 3354.6827539612323 1.567823580781237e-10 1.0026228794928967e-09 639.4998083861551 5.524315411999999e-11 2.2965765137478275e-10 415.721468176703 7.665548087030527e-11 4.1111846443684604e-10 536.3197253076065 6.765000000000036e-11 2.5276966986013087e-10 373.6432666077304 2.0428547914065776e-11 3.443187182398984e-10 1685.478183218411 9.57846230679511e-11 3.021039450414196e-10 315.39921060930874 6.292345769158467e-11 7.648041254395233e-10 1215.4515239581435 3.371860510481832e-11 2.1102601160296015e-10 625.8444290532202 +r_0999 sirohydrochlorin ferrochetalase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1000 fumarate reductase (FMN) 0.0025596671844227 0.0625469924145038 2443.559568804239 0.0050099835155193 0.1212110428443843 2419.390053258865 0.0092071721024716 0.2014871013739401 2188.371186412934 0.0136975223077859 0.3239739166899557 2365.200869253568 0.0199389486752978 0.4540880394304712 2277.3920873422844 0.0199696971458612 0.4770593533647246 2388.916315957236 0.0325882902385164 0.669824448555521 2055.414517463232 0.0598213920471779 0.9561358364357342 1598.3175979617483 0.0434738205433771 0.8997151274346894 2069.55615170048 +r_1001 spermidine synthase 9.120928257598966e-06 0.0002301838207408 2523.688535199612 5.8616525852272585e-06 0.000173019773969 2951.723450909722 8.48479150867681e-06 0.0002325337417375 2740.594645134119 6.758939095415775e-06 0.0002455872050271 3633.517058820101 2.3355820104313475e-05 0.0006425148012513 2750.9836879274617 3.4570421494921894e-05 0.0008320438958322 2406.808652751021 2.57578069000607e-05 0.0008501012349872 3300.363413258073 5.4879740611772174e-05 0.0016021778536185 2919.4340857996813 5.271975388883238e-05 0.0015391185502255 2919.434247494752 +r_1002 spermine synthase 6.922114697464577e-05 0.0006814726211189 984.4861735222712 0.0001105602915142 0.0011676567134643 1056.1266594647798 0.000101824313283 0.0009665437215369 949.2268500256064 0.000145516202751 0.0013559379592383 931.812357389616 0.0003294551856887 0.0030397067201673 922.6464940331896 0.0002865840450884 0.0026217873158646 914.8406412700264 0.0003761397745093 0.0039610757592758 1053.0861205631918 0.0006362435518895 0.0065346764211081 1027.0715360023576 0.0006541148499405 0.0064809765085717 990.801005230302 +r_1003 sphinganine phosphate lyase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1004 sphingoid base-phosphate phosphatase (phytosphingosine 1-phosphate) 0.0001757430176926 0.0035846593475069 2039.7165102609376 0.0001612574133276 0.0046527907781432 2885.3189953440005 0.000134068789694 0.0038697380208022 2886.382453091938 0.0003606872541778 0.0076930646397631 2132.8906277267024 0.0006517236604926 0.0145799004951086 2237.129228067085 0.0003861346232615 0.0102319354178414 2649.8363009814584 0.0011046186211277 0.0235272257442699 2129.8958114838097 0.0015161941261598 0.033792973204249 2228.8025405980466 0.0008802996785001 0.0253993914709115 2885.311910392534 +r_1005 sphingoid base-phosphate phosphatase (sphinganine 1-phosphatase) 0.0002045671246794 0.0038583341503982 1886.0968772206527 0.0003711529465348 0.0069974274933381 1885.321821817168 0.0003355723242765 0.0061023431454019 1818.488207738054 0.0003951490651476 0.0080674096765358 2041.6117329093347 0.0008451764375049 0.0165293469042211 1955.7273689524584 0.000846485310046 0.0149718911800177 1768.7124634451966 0.0012141462598571 0.0246149789053077 2027.3487403572533 0.0019556339515703 0.0383263090792854 1959.7895121686213 0.0022025895491785 0.0398331968149437 1808.4711620373864 +r_1006 sphingolipid long chain base kinase (phytosphingosine) 0.000175743495327 0.0035846593401656 2039.710962556416 0.0001612588017508 0.0046527907589009 2885.2941410853327 0.0001340704884912 0.0038697380200638 2886.345879402845 0.0003606885678888 0.0076930646206906 2132.8828539590195 0.000651724926886 0.0145799005145881 2237.124883998497 0.0003861348761435 0.010231935531631 2649.8345950564344 0.0011046202746975 0.0235272257135785 2129.8926203414226 0.0015161962265774 0.0337929731503208 2228.799449435616 0.0008803011202 0.0253993915053785 2885.3071889316 +r_1007 sphingolipid long chain base kinase (sphinganine) 0.0002045672379941 0.0038583341711816 1886.095842626028 0.0003711540555713 0.0069974275363903 1885.3161999317908 0.0003355734247309 0.0061023431787583 1818.4822542640209 0.0003951500819117 0.0080674096598825 2041.6064754058905 0.0008451774430956 0.0165293468718752 1955.7250382042344 0.0008464852796957 0.0149718910388097 1768.712510179926 0.0012141475844213 0.0246149788927708 2027.346527605384 0.001955634861864 0.0383263090758894 1959.788599767454 0.0022025906635913 0.039833196834289 1808.470247909792 +r_1008 spontaneous cis-aconitate(3-) to trans-aconitate 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1009 spontaneous cis-aconitate(3-) to trans-aconitate 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1010 squalene epoxidase (NAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1011 squalene epoxidase (NADP) 0.0008623714804604 0.000224763998761 26.06347773015944 0.00138103621801 0.0001556333837369 11.26931949410874 0.0031963661048037 0.0002342655662669 7.329121839793739 0.0047546468706592 0.0003634469398359 7.644036449451798 0.0067337803677773 0.000739564167261 10.982897078141423 0.0079601043498033 0.0007283952514121 9.15057415585503 0.0089484761904713 0.0011285873998419 12.612062387154923 0.0105267723674424 0.0015452951672322 14.679667359499671 0.0119053701075431 0.0015038728803876 12.631886844364349 +r_1012 squalene synthase 0.0008623714982153 0.0002247639967072 26.06347695539381 0.0013810362374761 0.000155633381479 11.269319171773128 0.0031963661344262 0.0002342655626035 7.329121657260243 0.004754646929789 0.0003634469323279 7.6440361964819346 0.006733780410235 0.0007395641616941 10.982896926220644 0.007960104381558 0.0007283952474033 9.150574068989227 0.0089484762345486 0.0011285873942459 12.612062262496664 0.0105267723796886 0.0015452951657406 14.679667328252362 0.0119053702382837 0.0015038728646872 12.63188657376864 +r_1021 succinate dehydrogenase (ubiquinone-6) 0.2696176784009587 0.1139573337781223 42.26626920533453 0.5169461322376173 0.2175550188399214 42.08465936251961 0.7577841367699619 0.3762109512713051 49.64618986020161 1.2393785326514837 0.6360723181319733 51.32187635775668 1.937936377378337 0.8527689218042644 44.00396895164847 1.7155146571795532 0.8406841349127058 49.0047771608585 2.6924713933552344 1.271663376754392 47.23033937863693 3.010120627767465 1.402229881012648 46.58384345389669 3.2937422425686056 1.4641287102143328 44.45183024013866 +r_1022 succinate-CoA ligase (ADP-forming) 0.2897287887481097 0.042866457646059 14.79537391892636 0.4735429009985573 0.0821652654447936 17.351176687800038 0.6808904413588466 0.1059920778708245 15.56668612637551 1.0872719031616884 0.2125438453733538 19.54836179940781 1.4692147422631403 0.3211902705598443 21.861356364086788 1.9132124404667683 0.2667432718611312 13.942166913573567 2.3286585409214524 0.3710156655066732 15.932592047602734 2.844741874745656 0.5575384925048928 19.598913260091184 2.1274250714995904 0.5463652881175359 25.68199911888841 +r_1023 succinate-semialdehyde dehydrogenase (NADP) 0.0002875024000065 0.005482092579086 1906.798892447733 0.0011233451122207 0.0125745238293711 1119.3820752478275 0.0008272919692358 0.0105225748519331 1271.9300130101851 0.0008772119933012 0.0123420446654301 1406.9625996541931 0.0011750274602619 0.0240228887099442 2044.4533870373352 0.0017979628312052 0.0232385359589288 1292.4925674548483 0.0021183091316912 0.0388316363544851 1833.14303722432 0.0029415860452364 0.0556225022877505 1890.901759539694 0.0034973171054996 0.0567931074336336 1623.905002618297 +r_1024 sucrose hydrolyzing enzyme 9.273999999999835e-10 2.737594360853615e-10 29.51902480972248 8.276000000000186e-10 3.958656109292533e-10 47.83296410454861 9.087999999999899e-10 2.9410858534221587e-10 32.362300323747704 7.82600000000034e-10 4.1925218482302837e-10 53.57170774635959 1.4479999999999939e-10 3.542005810417539e-10 244.6136609404388 9.061999999999916e-10 2.9969905556203246e-10 33.07206527941241 9.301999999999827e-10 2.6180463772374413e-10 28.144983629730056 7.430000000000393e-10 4.374806028335282e-10 58.88029647826446 7.664000000000397e-10 4.2973011716041287e-10 56.07125745829733 +r_1025 sulfate adenylyltransferase 0.0022004564410501 0.0055014055274521 250.01201681713675 0.0035998871736996 0.0103677843206594 288.003035106353 0.0085363252760068 0.0065023309096884 76.17248288282389 0.0143777092104919 0.0108946641047807 75.77468667143752 0.0159565395474097 0.0216447347247647 135.64804988233362 0.0218923132291439 0.0181037410892204 82.69450971092479 0.0259569554538473 0.0344044073603438 132.5440782973041 0.0330242725626919 0.0514802850837593 155.88620456675076 0.0353635094468713 0.0567235128931667 160.40125479736622 +r_1026 sulfate adenylyltransferase (ADP) 0.0002592162240167 0.0051804746166336 1998.5148060406552 0.0005295867791633 0.0102667539498059 1938.634866607688 0.0002345564916653 0.0062671656592913 2671.9216401963768 0.0004505688668265 0.0106120452733405 2355.254891018746 0.0009032543108305 0.0212728772409299 2355.137084413023 0.0007371441139358 0.0173607652740687 2355.13856054211 0.001508183954642 0.0336936611444033 2234.0551390098817 0.002264687485417 0.0506226619094941 2235.3045281288587 0.0028594038303725 0.0560101984250384 1958.806861419828 +r_1027 sulfite reductase (NADPH2) 0.0019022019139812 0.0014874796201224 78.19777749088672 0.0030198039409767 0.0008025208975584 26.575264925936903 0.0082202116404245 0.0007179256463959 8.733663776555536 0.0138265037359099 0.001297797340679 9.386301594874222 0.0149136709258091 0.0020079558340199 13.463860400359865 0.0209565393607519 0.0030291874453224 14.454616734076051 0.0241714400498447 0.0034074161766748 14.096868741160389 0.0304218362554367 0.0044002543010521 14.464131172442984 0.0321796500775713 0.0042820789616525 13.30679156339575 +r_1028 taurcholate via ABC system 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1029 taurine dioxygenase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1030 tetrahydrofolate aminomethyltransferase 2.952853812594864e-05 0.0014762888598809 4999.532498304219 0.0002411999650514 0.0056807898311618 2355.220005919078 0.0001135033863188 0.0035878811019222 3161.034413408588 0.0002121284623494 0.0058574813713952 2761.289695178217 0.0001338645704526 0.0066925974510218 4999.52857458115 0.0001641622468983 0.0067005654153272 4081.672578150253 0.0005855250244905 0.0169363272948464 2892.50272600762 0.0001527099398804 0.0107982392515776 7071.07818916972 0.0004997712331368 0.0168994268833386 3381.432496077768 +r_1031 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1032 thiamin diphosphatase 3.7540623989395105e-10 4.879605424950196e-10 129.98200100053322 7.33879859725615e-10 4.4881141827537774e-10 61.155979732592826 8.704410149128622e-10 3.6758420823401036e-10 42.22965162904327 7.811951220664699e-10 4.362818862611353e-10 55.84800441496015 2.3286719743506257e-10 6.155325194695944e-10 264.3277053399684 6.756047995200345e-10 4.852542737123055e-10 71.82516673313178 8.76574390928438e-10 4.640465196026061e-10 52.93863526073398 9.238739973599815e-10 5.189769613400479e-10 56.17399805850709 9.313541904145812e-10 4.6058746827966327e-10 49.45352402125751 +r_1033 thiamin phosphatase 9.616405208822827e-10 4.490503966511137e-10 46.69628482783986 8.82999999999999e-10 3.2516479887785957e-10 36.82500553543147 8.00400000000028e-10 4.1736636057039366e-10 52.144722709942414 7.850142461036517e-10 4.285742175696194e-10 54.594450953827824 5.298671980800233e-10 6.49068140311735e-10 122.49638072778173 2.9940000000000607e-10 4.684052953416962e-10 156.44799443610106 8.036000000000268e-10 4.1792579771353964e-10 52.00669458854229 7.898000000000314e-10 4.1910749243845596e-10 53.06501550246128 8.569417992800081e-10 4.3651130520338567e-10 50.93826740277309 +r_1034 thiamine diphosphokinase 2.5380062417791176e-08 9.339649058576206e-09 36.799157168459935 6.923020195566691e-09 1.6814546834592293e-08 242.8787777530948 3.1145876903269357e-10 5.722213992172329e-09 1837.2300160127047 5.452256259784331e-10 7.0361324218044794e-09 1290.4992147384498 2.0362823881343517e-10 1.1836469417249904e-08 5812.783868397799 5.122224456633006e-10 1.1159806453229812e-08 2178.703129414499 3.381378066635392e-10 1.1128296023276013e-08 3291.05347109237 1.339556305694486e-09 1.7165909610056568e-08 1281.4623422012105 1.2460771487881e-09 1.7629362316496565e-08 1414.7889906850785 +r_1035 thiamine-diphosphate kinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1036 thiamine-phosphate diphosphorylase 7.196804958198611e-05 0.001409711595915 1958.8020018649024 7.98881316422358e-05 0.0019591279494597 2452.339176278871 7.673153946926999e-05 0.0018046556832627 2351.9086098689945 0.0001007913068698 0.0025141497055371 2494.4112578907057 0.0002987550272904 0.0060901043241276 2038.4943407854544 0.0002364703755669 0.0048611648485491 2055.718327039671 0.0003777684656182 0.0084329394760852 2232.303710761984 0.0005159911083178 0.0121441684007788 2353.561564339669 0.0004956505523246 0.0116640890430035 2353.288821791402 +r_1037 thioredoxin -2.0707676820521754e-09 1.9621362356428834e-09 -94.75404955607402 -1.6880111769734623e-09 2.046179754309352e-09 -121.21837711869136 -2.654428142150742e-09 1.8857375130700263e-09 -71.04119652461617 -1.6422190909762611e-09 1.926255531240496e-09 -117.29589199303376 -2.323018430929602e-09 1.9032747389811647e-09 -81.9311079774572 -5.556051799579467e-10 1.6251313634242966e-09 -292.4975183901816 -1.245420960212124e-09 1.931375218324331e-09 -155.07810451458698 -2.0130000000000616e-09 1.9839400705768797e-09 -98.5563870132548 -2.3033616022424282e-09 1.7323565858049871e-09 -75.2099272697113 +r_1038 thioredoxin reductase (NADPH) 0.0022679018262271 0.0020691274189867 91.23531693737053 0.0036500260889903 0.0023684871988241 64.88959643242896 0.0094653697500219 0.002437852351917 25.75548992062753 0.0155882244922965 0.0032679087887738 20.96395770017806 0.0175643644852396 0.006297297109327 35.852689772061105 0.0239786206410878 0.0063139636142782 26.331638123750515 0.0276970858763664 0.0093116615385958 33.6196435255356 0.0349423715855716 0.0143542365594439 41.07974332621161 0.037064023524855 0.0136690170616153 36.879474384233845 +r_1039 thioredoxin reductase (NADPH) 9.919999999999612e-10 9.131082922362471e-11 9.204720687865755 9.91399999999961e-10 9.44871714314276e-11 9.530680999740898 9.92199999999961e-10 8.798129427115606e-11 8.867294322834057 9.911999999999614e-10 9.340398739332864e-11 9.423323990449182 9.937999999999603e-10 7.850345571063571e-11 7.899321363517692 9.951999999999601e-10 6.912246800509983e-11 6.945585611445197 9.91399999999961e-10 9.234579334820406e-11 9.314685631249512 9.9419999999996e-10 7.594414725770619e-11 7.63871929769757 9.97199999999959e-10 5.284617813720442e-11 5.299456291336399 +r_1040 threonine aldolase 3.540529549595398e-05 0.0005148383579599 1454.128120520265 8.598472485561732e-05 0.0019246884097111 2238.407360078171 0.0001789270320528 0.0027898260062924 1559.1976093742835 0.0001996870028248 0.0028646092627883 1434.5496813833724 0.0005360056731925 0.0087323393909668 1629.1505533804234 0.0001453312303861 0.0024398464748104 1678.81773816059 0.0009912247494719 0.0138944368397412 1401.744341749292 0.0013613145744996 0.0203574154426062 1495.4233080247536 0.0012732913962318 0.0195747497878187 1537.334646707525 +r_1041 threonine synthase 0.0035554237539221 0.0014893490373532 41.88949448600348 0.0059933645760891 0.0023569370866125 39.325775308509 0.0164856545207451 0.003992407429455 24.217463883105538 0.027747923354797 0.0057008529597923 20.545151746668537 0.0301881080222792 0.0109578585356316 36.29859323262191 0.0415594698069871 0.0073532288012708 17.69326903211514 0.0490119747808532 0.017977275919901 36.67935438284749 0.0620192780309862 0.0264247527108737 42.60732073932135 0.0652199077805943 0.0250444428629812 38.39999735545941 +r_1042 threonyl-tRNA synthetase 0.0034363772325584 2.5389881482563862e-05 0.7388560616105828 0.0058418114607537 3.604053852232946e-05 0.6169411451303375 0.0161312882199698 4.5450808332873415e-05 0.2817556026096363 0.0270820667043587 7.332040290934475e-05 0.2707341493163966 0.0291636370129339 0.0001227921960956 0.4210455508041703 0.0408307802243081 0.0001189247174308 0.291262417170428 0.0472839182201766 0.0002234009583465 0.4724671024643905 0.0595070120439957 0.0003493284633635 0.5870374790541503 0.0629645629988718 0.0003170034628097 0.503463293814066 +r_1043 threonyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1045 thymidylate synthase 9.736618086692149e-05 0.0002851035688861 292.8158076528387 0.000160719319774 0.000471682362424 293.4820549807285 0.0003427134006435 0.0005740250284112 167.49418824399334 0.000496090683324 0.0007419618574646 149.56173990067964 0.0007705809896129 0.0019852790312682 257.6340524914016 0.0008484618504976 0.001215510414636 143.2604676242266 0.0009484051784099 0.0020748063934326 218.76793175162555 0.0013207795878802 0.0046918086435369 355.2302508753048 0.0014104783997891 0.0043014622087427 304.9647700656576 +r_1046 trans-aconitate 3-methyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1047 trans-pentaprenyltranstransferase 7.822465069860881e-10 6.938087219668316e-10 88.69438415775129 7.90449561435883e-10 1.5829857838973847e-09 200.2639840829095 8.207892748286725e-10 1.3643281506059452e-09 166.22148856546983 7.812999999712787e-10 4.162123667379482e-10 53.27177355090854 8.167396187146554e-10 5.457842718724277e-10 66.82475777670194 8.241174790425943e-10 4.025537799413841e-10 48.84664992290234 7.93944218459268e-10 7.750497096279875e-10 97.6201717460772 8.072836757657396e-10 4.140462956313487e-10 51.28882300742795 7.420672707783386e-10 6.287802349374792e-10 84.73358948683517 +r_1048 transaldolase 0.0501776364300919 0.0412916481573876 82.29093894232287 0.1031157356363068 0.0811237297671207 78.67250256861598 0.2176880507369629 0.1044662063327711 47.988948396161575 0.3662573721422635 0.1813180944807424 49.50565047201668 0.524516160629922 0.3135717306564563 59.78304467871301 0.4750533258464625 0.2622129086091201 55.19652096780974 0.6579182702637992 0.3721494187932258 56.56468829236321 0.8028684022125946 0.542795391230447 67.60701875109018 0.9972613273006616 0.4154544152710541 41.65953335376855 +r_1049 transketolase 1 0.0499937784875045 0.0407565245319581 81.5231930151965 0.1027812654593585 0.0799789297625145 77.81469648682182 0.2175070944385748 0.1043787441517796 47.98866189684528 0.3659890075086542 0.1812585366222552 49.52567779456303 0.5238598156196831 0.3113362200514741 59.43120864943401 0.4746148466979837 0.2619767219834855 55.19775114624505 0.656801481046694 0.3701946529858294 56.36324881543791 0.8016563341765163 0.5413964231128291 67.53472779192428 0.996551962017909 0.4138905658851568 41.53226140331645 +r_1050 transketolase 2 0.0447732525432969 0.0408056128551216 91.1383706503375 0.0941901443035399 0.0799854077695299 84.91908400922145 0.1940293366158916 0.1044076620314243 53.81024532290909 0.3268756097990933 0.1812055398332887 55.435625785803545 0.4810232848461896 0.3114085179673376 64.73876167281851 0.4152783783304107 0.2621389992467818 63.12368110776392 0.5876692727413408 0.3704119602814469 63.030683662183165 0.7142794082014312 0.5412960225750404 75.78211220424704 0.9044570996074452 0.4138263683704763 45.75411797310081 +r_1051 trehalose-phosphatase 0.0041534285144864 0.0012366509657535 29.77422053708967 0.0066255725932835 0.0024597878838437 37.125664977806174 0.0133980384893657 0.0020362559115186 15.198164366633668 0.017714913178313 0.002842720903976 16.047049598053707 0.0313724157964781 0.0052731264461366 16.808161922706045 0.0327075269804946 0.0045331090469501 13.859528571675703 0.0357284868531553 0.009090939908975 25.444514194902656 0.0392078864159326 0.0128001720191976 32.64693200599586 0.0475341270901428 0.0122965353135069 25.86885689556896 +r_1054 triose-phosphate isomerase 0.2433541569637377 0.0428054180129183 17.58976240512578 0.3398957018186918 0.0801054716604815 23.567662442289915 0.8292704380241308 0.1107003132599302 13.349120887956811 1.1343918191258655 0.1816187678141128 16.01023250979223 1.575069059187657 0.3206529154171498 20.35802262426047 2.007689422446296 0.268104559146124 13.353886121462372 2.230314002859392 0.3857172705290359 17.29430340456653 3.978550433463219 0.602012069970836 15.13144246978418 5.736702690044624 0.4596185723693055 8.01189458827838 +r_1055 tryptophan synthase (indoleglycerol phosphate) 0.0007737518153022 0.0008148460998492 105.31104208537975 0.0012740322982829 0.0011740986210346 92.15611116115667 0.0032656281543926 0.0010881926658517 33.32261403944658 0.0053687698439837 0.0016457218085825 30.65361072288676 0.0061360165776296 0.0031701864750798 51.66522017944892 0.0082570269352965 0.0029871037225427 36.17650452093957 0.0095591523757171 0.0044449359943102 46.49926917789934 0.0121484645565081 0.0073750348900048 60.70754749046805 0.0129384841067491 0.0075400232207679 58.27593989032178 +r_1056 tryptophan transaminase 1.1068448420299968e-05 0.0002561079885175 2313.856276800887 3.0153212462792608e-06 0.0001507475656835 4999.386578447526 1.3634499854192331e-11 3.287291336978854e-10 2411.00984424308 6.289810540500196e-06 0.0003144574740567 4999.474499779749 3.680713422107242e-05 0.0008934320854666 2427.334005686249 5.390420900431605e-06 0.000381159742952 7071.057158478592 1.2233055967869876e-05 0.0007109719288506 5811.89140896643 4.98466954660656e-05 0.001851563104933 3714.515250451328 0.0001006685393574 0.0021051283262492 2091.1481776587343 +r_1057 tryptophanyl-tRNA synthetase 0.0005635868757062 4.164095793596356e-06 0.7388560616104736 0.0009580927956443 5.910868664860149e-06 0.6169411451303822 0.002645629892688 7.454210446962581e-06 0.2817556026095907 0.0044416245157732 1.2024994348606072e-05 0.2707341493163716 0.0047830147728321 2.013867089531031e-05 0.4210455508040515 0.0066964975909038 1.9504380749024992e-05 0.2912624171704138 0.007754851675878 3.663912301342997e-05 0.4724671024643588 0.0097595137933996 5.729200374072165e-05 0.5870374790542121 0.0103265732890192 5.199050601903048e-05 0.5034632938141703 +r_1058 tryptophanyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1063 tyrosine transaminase 0.0017977885427247 0.0014035879904206 78.0730301180682 1.0031122945304969 31.610017681497368 3151.19432329282 0.0099022789420423 0.0207908236557209 209.95998777058108 1.814157479051399 42.39183116916456 2336.7227850214376 0.0170048031046181 0.0428877931101976 252.20987768185444 2.2220016661591764 46.85616938818219 2108.7369150885943 1.624803613306585 39.97097069080521 2460.049347715419 1.2309777606072316 34.6226070916058 2812.610284244838 0.0365499642677978 0.0995393051240509 272.33762636465696 +r_1065 tyrosine transaminase 7.597999999858374e-10 4.3421385091538607e-10 57.1484405005896 -6.759999999579642e-10 1.3713497437715564e-09 -202.8623881445017 7.143999998621776e-10 4.66557794015515e-10 65.30764195206096 -4.189999936170242e-10 1.3029883052448623e-09 -310.975733912737 5.425999981863029e-10 8.83595714436551e-10 162.8447691467125 7.333999998953862e-10 5.926168060929857e-10 80.80403683903977 -4.439999998263767e-10 1.362951036022971e-09 -306.9709541792667 -5.200000040212859e-10 1.2399626962395467e-09 -238.454362817426 2.2140000002278188e-10 5.032223033293017e-10 227.29101322381248 +r_1066 tyrosyl-tRNA synthetase 0.0017976660964393 1.3282164921060282e-05 0.7388560616105864 0.003056016756626 1.8853824773708047e-05 0.6169411451304762 0.0084387329918799 2.3776602993887187e-05 0.2817556026096086 0.0141673948583625 3.8355975950079664e-05 0.2707341493163743 0.0152563231447061 6.423606981708404e-05 0.4210455508041162 0.021359735655613 6.221288237174729e-05 0.2912624171704049 0.0247355546084607 0.0001168673581371 0.4724671024644302 0.03112980060465 0.0001827435967041 0.5870374790541776 0.0329385432739329 0.0001658334749013 0.503463293814153 +r_1067 tyrosyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1068 UDP-glucose:ergosterol glucosyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1069 UDP-N-acetylglucosamine diphosphorylase 0.0007085715862576 5.235149712073786e-06 0.7388314481707232 0.0011247271352592 6.938686650961745e-06 0.6169217789310731 0.0022993743987335 6.478302558520923e-06 0.2817419626003129 0.0030401704125069 8.230463246260732e-06 0.2707237466821443 0.0053857096488761 2.2676215868347768e-05 0.4210441584625627 0.0056201891301919 1.6369195204353745e-05 0.2912570168932125 0.0061005484728371 2.882266337072836e-05 0.4724601976209531 0.0066801214129222 3.921424891743436e-05 0.5870289848561279 0.0081236581114857 4.089917258946136e-05 0.5034575806635136 +r_1070 UDPglucose 4-epimerase -2.0779999369979975e-10 4.4973281172110727e-10 -216.4258062350175 -8.572000000106875e-10 5.382063667606682e-10 -62.78655701749391 -4.995646707933727e-10 5.21312183097073e-10 -104.35329269164735 -4.976000000053612e-10 5.510489733223146e-10 -110.74135315843606 -2.2602527889553863e-10 4.717629494345532e-10 -208.7213216768495 -1.4579999997171743e-10 4.679595678935584e-10 -320.9599231716969 -2.3262579683762662e-10 5.856546513732875e-10 -251.7582569666924 -3.3000000000545396e-10 5.035381913513051e-10 -152.58733070999486 -1.6640000001654683e-10 4.0341490892792456e-10 -242.43684428353905 +r_1071 UDPglucose--hexose-1-phosphate uridylyltransferase -0.0002879009610446 0.0066011108510077 -2292.840852998988 -0.0001369397381843 0.0056173488844553 -4102.059021679489 -0.0004688462574416 0.0119277179279285 -2544.0574044494165 -0.0005943208658192 0.0149685054648189 -2518.589927712879 -0.0009742123473489 0.0273708675271601 -2809.538146548966 -0.0009852326171812 0.0268587644512288 -2726.134314155423 -0.0021245694541478 0.0466979690821907 -2197.9968219453385 -0.0014178967856659 0.0449835157333407 -3172.5522046524675 -0.0022363254231102 0.0570859031807114 -2552.6653049141883 +r_1072 UMP kinase 0.0013808679176696 0.0039621758407748 286.93373132032474 0.002379312512557 0.0079923666564484 335.91075633267985 0.0047531534178801 0.0072847808472692 153.26206008553848 0.006743312420014 0.0078233803313494 116.01687485411144 0.0102362963969983 0.0198413722367771 193.8335064486346 0.0116778485647067 0.0167132681433383 143.11941151429008 0.013509863301755 0.0280050849765446 207.29362208207127 0.0172720079850737 0.0468547460840023 271.27561615588473 0.018343191726996 0.0422597294195993 230.3837306427152 +r_1073 UMP kinase 0.0001070081858515 0.0027985145335986 2615.234069551125 0.0002459948150085 0.0057592553675181 2341.210064658366 0.0002972726046996 0.0057385684302796 1930.4060783125408 0.000324886996776 0.0073309247942453 2256.453741452303 0.0006944232869266 0.015278690367134 2200.1984459296177 0.0006389243234497 0.0132560113328856 2074.738876947454 0.0013920116163819 0.026198090402897 1882.031018605332 0.0010970547409219 0.0290094468801671 2644.302585647547 0.0018160514035914 0.034909973463004 1922.30095436541 +r_1074 uracil phosphoribosyltransferase 2.657588241151521e-05 0.0010847376104388 4081.66168724783 4.8333905601233976e-05 0.0019728086249475 4081.624690592286 6.716035688714955e-05 0.0021238212821577 3162.313871747923 0.0001567187961406 0.0039176843000339 2499.817760543148 0.0002007319770019 0.0063451718402403 3161.016961527742 9.610253165987588e-05 0.0039250222155089 4084.2027236080257 0.000359540266663 0.0103752484961994 2885.6986152051554 0.00053692862602 0.0154940828727721 2885.6876169223574 0.0003472276943781 0.0122765457732857 3535.589462490906 +r_1075 urea carboxylase 2.208405176428767e-05 0.0005200658492139 2354.938553689484 4.358923884859727e-05 0.0009771525644626 2241.728899778792 2.260331663815958e-05 0.0006522041041817 2885.4354191571724 1.666780635642271e-05 0.0006803470166458 4081.80298053274 7.813600462810236e-05 0.0020870214686943 2671.0112433158097 7.271419336148146e-05 0.0018165866170908 2498.255888035717 6.700754795913863e-05 0.0023683842515471 3534.50368455714 0.0002543097905169 0.0056814606987191 2234.0707713888664 0.0001712404585444 0.0045738471238515 2671.008453685351 +r_1076 ureidoglycolate hydrolase 9.671999999999735e-10 3.8282302790472006e-10 39.58054465516238 1.5265643323455337e-10 6.147367042391067e-10 402.6929564734276 3.44625724935981e-10 8.572499459552027e-10 248.7481008895807 5.713401124840548e-10 7.76691605111166e-10 135.94207515630058 1.6638304310457538e-10 6.722049567051101e-10 404.0104953980283 9.56894801699484e-10 3.1097051888444505e-10 32.497879425423655 2.2904599501877203e-10 6.9635515679101e-10 304.0241575644833 2.5985264174800496e-10 7.55019495754971e-10 290.5567904470873 3.9250278571453825e-10 6.278534846195e-10 159.96153593572942 +r_1077 uridine kinase (ATP:uridine) 9.10383840659376e-05 0.0020437163149389 2244.895200972279 0.0001839848435108 0.0041324868877869 2246.101803240397 0.0001723497267487 0.0038164546916095 2214.3665462109384 0.0002928724781369 0.0061338019192939 2094.35927824726 0.0006606934642136 0.0137441286591723 2080.2580021780773 0.0004448887803417 0.0098953037564142 2224.2196687478536 0.0007151729624359 0.0166811622642387 2332.465451073573 0.0014788996442497 0.0299663781714084 2026.2617742809407 0.0014332534849531 0.030118664878824 2101.4192670745897 +r_1078 uridine kinase (GTP:uridine) 2.529688880596919e-12 1.337907494251347e-09 52888.22291599936 5.3753737812798974e-05 0.0026873681330541 4999.407003868517 1.3198232870458675e-11 6.088064622226477e-10 4612.787698157124 4.371854984368549e-05 0.0024785632970154 5669.363018392714 1.9475915567018423e-05 0.0013771481221036 7071.031486888106 7.137258049283759e-05 0.0040443063929077 5666.470744060587 0.0001124949350854 0.0071671842048535 6371.117241331372 1.2369236638365515e-10 7.858551560772977e-09 6353.303595468616 1.2855159076423326e-10 8.819213254758832e-09 6860.446613168314 +r_1079 uridylate kinase (dUMP) 6.196684278588237e-05 0.0016551384178386 2671.0065309567262 0.0001059919594529 0.0028468103249312 2685.873852719153 9.516804393418598e-05 0.0025419484965314 2671.0105529639145 8.014638377224699e-05 0.0028327613882818 3534.4843459583926 0.0002807717710016 0.0074994387409126 2671.0088105223845 0.0002947754589884 0.0069423683978407 2355.137846842593 0.0003012148934344 0.0095214498430337 3161.0156239194266 0.0002747169157736 0.0112130310655279 4081.667499051562 0.0006157028035237 0.0164454765371418 2671.008876851464 +r_1080 uridylate kinase (dUMP) 5.314041267039729e-05 0.0015332763585685 2885.3301687336075 8.048452208023578e-05 0.0025441526653931 3161.0458752017653 2.724953696838177e-05 0.0013623530761376 4999.545782074721 0.0001006362856801 0.0031811321254448 3161.019014112669 0.0003214741777921 0.0080312309010506 2498.250701256506 0.0001313295685347 0.0046418224500869 3534.4838956503063 0.0002413369005822 0.0085300059570609 3534.480610499503 0.0002750238372196 0.0112255666848655 4081.670446587641 0.0001761327202205 0.0088057761473657 4999.511809243008 +r_1081 uroporphyrinogen decarboxylase (uroporphyrinogen III) 1.3958217504192468e-05 0.0001439643151369 1031.3946970215925 8.005753318949784e-06 0.0001060046104505 1324.1053805592123 1.4419801075164914e-05 0.0001678547888321 1164.057589679841 1.3930017012026926e-05 0.0002030935219423 1457.956022357854 4.532236219298812e-05 0.0005130161546369 1131.9272205020063 3.858790289326032e-05 0.0004661301034462 1207.9695150462333 4.060617428819309e-05 0.0005824694784026 1434.435744349492 9.34694012777442e-05 0.0011187944996471 1196.9633744872604 9.266277582557682e-05 0.0010814233914153 1167.0526614171088 +r_1082 uroporphyrinogen methyltransferase 2.2801938289599544e-11 7.649326913700785e-10 3354.6827539612323 1.567823580781237e-10 1.0026228794928967e-09 639.4998083861551 5.524315411999999e-11 2.2965765137478275e-10 415.721468176703 7.665548087030527e-11 4.1111846443684604e-10 536.3197253076065 6.765000000000036e-11 2.5276966986013087e-10 373.6432666077304 2.0428547914065776e-11 3.443187182398984e-10 1685.478183218411 9.57846230679511e-11 3.021039450414196e-10 315.39921060930874 6.292345769158467e-11 7.648041254395233e-10 1215.4515239581435 3.371860510481832e-11 2.1102601160296015e-10 625.8444290532202 +r_1083 uroporphyrinogen-III synthase 1.395825128638109e-05 0.0001439643589443 1031.3925146542088 8.00589842634533e-06 0.0001060046086754 1324.0813588962028 1.44197537700597e-05 0.0001678548455166 1164.0618015623809 1.3930564342544362e-05 0.0002030935084563 1457.8986425987962 4.532279065521537e-05 0.0005130161656274 1131.9165439969725 3.85879621442002e-05 0.0004661301422831 1207.9677608816532 4.0606739097514856e-05 0.0005824694860823 1434.4158113350682 9.346966994326816e-05 0.001118794512622 1196.9599478644732 9.26633394698876e-05 0.0010814233868257 1167.045557620077 +r_1084 UTP-glucose-1-phosphate uridylyltransferase 0.0447020686446965 0.006266393692795 14.018129099576838 0.0709251888808492 0.0086388402085453 12.18021459633786 0.1442881534866587 0.009356587484965 6.484653978076054 0.1910687113249389 0.0160162805701183 8.38247165590628 0.338788519357132 0.0287567199613167 8.488103438653726 0.353052960966095 0.0241828328933984 6.849633218547299 0.3839377250356785 0.0434737062878893 11.323113998201002 0.4217422338053164 0.0563953990846633 13.372006539590831 0.5119074847064945 0.0601165836221617 11.74364224360384 +r_1085 V-ATPase, Golgi 5.905772146422933e-05 0.0020873699465121 3534.4572983168937 0.0002150114450356 0.0053715069511156 2498.242337855408 0.0001135407188987 0.0035890357185135 3161.0119729064672 0.0001341819752232 0.0047426246745956 3534.4722468902964 0.0003344840254988 0.0105731086434655 3161.0205084373865 0.0001094415882072 0.0054715324307206 4999.500208603688 0.0004021666499606 0.0142145054379493 3534.481399524735 0.0006111647893092 0.0216014531170888 3534.47277967407 0.0002935551719159 0.0146762898735746 4999.49967762057 +r_1086 V-ATPase, vacuole 2.090972078916578e-05 0.0005523586758268 2641.635827643723 0.0001503057213428 0.0042917318702647 2855.3350011717835 0.0002250893100739 0.0048419237035695 2151.1122416156427 0.0004226111498769 0.0082466587548884 1951.35853781674 0.0004283859140416 0.0116635377997774 2722.670708225978 0.0004171735386712 0.0103176932066764 2473.2376937281306 0.0003825383126356 0.0126493898567302 3306.698816538455 0.0014609631071117 0.0324634232674323 2222.0563345786068 0.0017954336050495 0.0355678213425136 1981.0156857085087 +r_1087 valine transaminase 0.000559022864619 0.0047753110697362 854.2246430278402 0.0001814605502802 0.0017002922433171 937.0037954206504 0.0005783805739791 0.0049220495149004 851.0053304587277 0.0005659415258841 0.0056082428140893 990.957997882928 0.0010291507987693 0.0107730896015088 1046.794076669008 0.0016617469468567 0.0134773160364482 811.0329952428252 0.0017801085342395 0.0173955775810347 977.220054083184 0.0028194462330122 0.0267706493664663 949.5002618959296 0.0025605915154587 0.0254117105320194 992.4156343799426 +r_1088 valine transaminase, mitochondiral -0.0051560627485362 0.0047746120623648 -92.60189984538648 -0.0079963892947012 0.0017001356687363 -21.26129189161612 -0.0221581368660186 0.0049209279743479 -22.20822086307528 -0.036795187161741 0.0056070064077003 -15.238423392313532 -0.04004303320997 0.0107709489797662 -26.898434300138096 -0.0562834407918412 0.0134738086618052 -23.939205692197863 -0.0650345382094377 0.0173912785592007 -26.741603827790232 -0.0824254148152934 0.0267639712288961 -32.47053264927008 -0.0867919258688084 0.0254059075768215 -29.27220167371813 +r_1089 valyl-tRNA synthetase 0.004597040400117 3.396551165095234e-05 0.7388560616105848 0.0078149287687361 4.821351103696628e-05 0.616941145130403 0.0215797564221241 6.080217274883636e-05 0.2817556026095849 0.036229245607568 9.808493989939635e-05 0.2707341493163941 0.0390138824959624 0.0001642662164451 0.4210455508040697 0.0546216941728776 0.0001590924667473 0.2912624171704215 0.0632544297740334 0.0002988563715337 0.4724671024644433 0.0796059687116581 0.0004673168719015 0.5870374790541287 0.084231334423671 0.000424073850713 0.5034632938141267 +r_1090 valyl-tRNA synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1091 xanthine phosphoribosyltransferase 1.0221505361352455e-05 0.0004172063721559 4081.6529210404383 2.4808432490229773e-05 0.0008768650529549 3534.5443663169867 1.470394807197331e-05 0.0006030352257817 4101.178967920398 2.322363516095709e-05 0.0009479166472544 4081.6893681144415 4.636638905503409e-05 0.0018925252101575 4081.674783669807 2.5255558797089246e-05 0.0012626616050084 4999.5393693445085 9.292540270987716e-05 0.0032844264907303 3534.4764670912205 0.0001410378975399 0.0049849502892966 3534.475751728794 0.0001016152216088 0.0041475944275383 4081.666468735616 +r_1092 xylitol dehydrogenase (D-xyulose-forming) 9.78199999999966e-10 1.6164772190537762e-10 16.525017573643755 9.957999999999599e-10 8.592925443265894e-11 8.629167948650572 9.947999999999602e-10 7.193048588018586e-11 7.23064795739734 9.985999999999587e-10 4.240754272456597e-11 4.246699651969528 9.903999999999618e-10 9.751790578345312e-11 9.846315204307036 9.78399999999966e-10 1.6594862997191448e-10 16.96122546728539 9.91599999999961e-10 9.1274893707106e-11 9.204809772802497 9.853999999999635e-10 1.216133132497972e-10 12.34151748019096 9.935999999999607e-10 7.975156463927491e-11 8.026526231811399 +r_1093 xylose reductase -1.240000000000001e-11 1.8829054853107157e-10 -1518.4721655731566 -2.800000000000001e-12 7.741678546500293e-11 -2764.8851951786755 -2.600000000000001e-12 5.092895788988538e-11 -1958.806072687899 -1.4e-12 4.240754272456608e-11 -3029.110194611863 -1.4e-12 3.7394112690807915e-11 -2671.0080493434225 -2.0799999999999976e-11 1.7312814523045018e-10 -832.346852069473 -2.259999999999997e-11 1.4863935794986484e-10 -657.6962741144472 -2.559999999999996e-11 1.7248359376480875e-10 -673.7640381437853 -1.6e-12 3.9971984588089866e-11 -2498.2490367556165 +r_1094 xylulokinase 9.869999999999632e-10 1.1676355058556673e-10 11.830146969156138 9.97199999999959e-10 6.923235243529783e-11 6.942674732781855 9.953999999999604e-10 8.354780695631922e-11 8.39339029097072 1.0005999999999583e-09 6.164738502171796e-11 6.161041877045827 9.90599999999962e-10 1.2535861740059935e-10 12.654817020048876 9.789999999999655e-10 1.5153743009086326e-10 15.478797762090762 9.761999999999688e-10 1.9401311351979755e-10 19.87432017207578 1.0353999999999592e-09 3.1838202433976063e-10 30.749664317150188 9.931999999999608e-10 9.775311316898078e-11 9.842238538963416 +r_1095 yUMP synthetase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1096 (R)-mevalonate transport -8.408384159608025e-05 0.0012417800680464 -1476.8355542217594 -2.6547318898121768e-05 0.0006620462425139 -2493.8346695370706 -7.513428593034895e-05 0.0014193039289597 -1889.022982497573 -4.9698178447620224e-05 0.0014344820845452 -2886.38764911095 -0.0002422569149972 0.0040840400097718 -1685.8301071891508 -0.000182057134202 0.0034352208484097 -1886.8916417181183 -0.0004783329664688 0.0074234216939975 -1551.9360391984058 -0.000541335748923 0.0085135974472776 -1572.701870182192 -0.0006907548106326 0.0105166482990057 -1522.4864361600476 +r_1097 (R,R)-butanediol transport 0.0015070825174226 0.0062839093278426 416.9585444192699 6.305953347999993e-05 0.0011576634324264 1835.8261923926084 0.0001913371173377 0.0034233427901481 1789.1681644311898 0.0001223367881366 0.0025356126323256 2072.6493403551744 0.0005083854191213 0.0096208375828497 1892.4298811474628 0.0011805449827427 0.0121992120048953 1033.3542713936592 0.0007819630571066 0.01382761712777 1768.3210225984865 0.0017768140642608 0.022494416390013 1265.997204911319 0.000999675184675 0.0203790433044207 2038.5664880784127 +r_1098 2-methylbutyl transport 3.1487820865762914e-05 0.0008447314832724 2682.724494888517 1.0333232992849792e-05 0.0003266328302939 3160.993568227872 2.9281539198500488e-05 0.0007821123460562 2671.0083126240866 2.611274292325729e-05 0.000825457489615 3161.129001426418 4.934912123993792e-05 0.0017442311907748 3534.472645002789 0.0001014208307995 0.0025337801465102 2498.2837613678444 0.0001297263399937 0.0034650053329373 2671.0114022374305 0.0001407287234184 0.0044484520674196 3161.0121653640304 0.0001504662905913 0.0044073109023128 2929.101850647225 +r_1099 2-oxoadipate and 2-oxoglutarate transport 0.004813227326796 3.556267182060622e-05 0.7388529443149939 0.0081824453907497 5.0480787401053e-05 0.616940107637278 0.022594599529601 6.366143382880475e-05 0.2817550881811481 0.0379330186829625 0.000102697486902 0.2707337577333327 0.0408486101048924 0.0001719910494753 0.4210450466582642 0.0571904195277281 0.0001665740336442 0.2912621292513366 0.0662291318641015 0.0003129107419644 0.472466923779927 0.0833496440291107 0.0004892934691728 0.5870372631728625 0.0881925296371844 0.0004440169180408 0.5034631843166931 +r_1100 3-hexaprenyl-4,5-dihydroxybenzoate transport -4.1733333333333107e-11 1.878499630898041e-10 -450.1197198637502 -7.513204228042823e-11 4.130214031910956e-10 -549.7273741734649 -3.5466666666666553e-11 1.7861705383724655e-10 -503.619512699005 -5.359999999441368e-11 2.333908044112512e-10 -435.43060529025325 -3.1666666666666596e-11 1.9721533887882944e-10 -622.785280669989 -4.553333333333293e-11 1.6785945120567195e-10 -368.65179620572496 -6.646666667769803e-11 2.1294789772405887e-10 -320.38299551963337 -1.4293333333333222e-10 3.3332175748387165e-10 -233.20085644860603 -2.127333333388507e-10 1.845601595465033e-10 -86.75657765984799 +r_1101 4-aminobutyrate transport 1.0900000000000048e-10 3.1739430969940484e-10 291.1874400911957 3.294000000000084e-10 4.70042368266525e-10 142.6965295283889 3.8380000000001247e-10 4.896381409794494e-10 127.57637857723653 2.650000000000036e-10 4.413773473939748e-10 166.55748958262978 3.339999999999992e-11 1.7969668383038655e-10 538.0140234442725 6.920000000000034e-11 2.7789711290523387e-10 401.5854232734575 1.2320000000000008e-10 3.3293231862611086e-10 270.2372716121028 1.8699999999999806e-10 3.9504710154927677e-10 211.255134518332 8.946799709223912e-11 3.1782833547208356e-10 355.2424842420593 +r_1102 5-aminolevulinate transport -1.8219999999999824e-10 4.5852503643945663e-10 -251.660283446466 5.199999999999999e-12 2.6755798895845713e-10 5145.345941508792 1.4400000000000002e-11 1.7719740343458599e-10 1230.537523851291 -9.200000000000807e-12 1.7413048063121715e-10 -1892.7226155565425 -4.800000000001009e-12 2.1350896284570566e-10 -4448.103392617935 -5.5799999999997975e-11 4.4757840127184125e-10 -802.111830236304 -2.0400000000001197e-11 2.2714347631347195e-10 -1113.4484133012677 1.499999999999946e-11 2.6455433808495113e-10 1763.695587233071 -9.800000000000872e-12 1.8791227262859856e-10 -1917.472169679407 +r_1103 5-formyltetrahydrofolic acid transport 1.3424476882824391e-11 1.5958519178525811e-09 11887.628335777865 6.735358083954202e-11 2.4409520928581157e-09 3624.0865926241577 -1.2254175215846348e-10 1.6340966317569784e-09 -1333.5019313612102 7.965331408164395e-10 7.692033188547562e-10 96.56890334359842 2.0677770457903015e-10 7.476245190839511e-10 361.5595407667415 4.710282754814631e-11 9.151076087717051e-10 1942.786996887448 1.69303876234277e-10 7.362293523789942e-10 434.8567609640698 1.2614964683829328e-10 7.89946618314688e-10 626.1980418599921 1.1528837949269623e-09 7.53382025350647e-10 65.34761167307201 +r_1104 8-Amino-7-oxononanoate transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1106 acetate transport 9.601854562010268e-05 0.0009750919572187 1015.5246061283916 2.8121762517691225e-05 0.0004923526983791 1750.7889061697756 0.0001095414821605 0.0010392661247568 948.7420694509248 8.637317128871613e-05 0.0009237667427812 1069.5065713095391 0.0001119876539994 0.0010523493777484 939.7012439904646 0.0001036188698025 0.0010112209192376 975.9042162538896 0.0001025068910123 0.0009977976160159 973.3956480013738 0.0001159687261709 0.0010705905173584 923.1717487181228 0.0001119454214394 0.0010519522402497 939.7009960058676 +r_1107 acetic ester transport 0.0004089814647661 0.0047101455876273 1151.677030234151 2.7390540629527444e-05 0.0008632934510817 3151.7941276086726 0.0002372391297508 0.0046348449640506 1953.659570795865 8.473849746521048e-05 0.0020528617523585 2422.5845557402235 0.0007482768672045 0.0123634461975153 1652.25556734136 0.0014183922922463 0.0173771231774675 1225.1281449046023 0.0009566635988363 0.0168169615245565 1757.876179778522 0.0017944536552607 0.0326922013723234 1821.847071752452 0.0012119925667599 0.0255913945349434 2111.514149245799 +r_1108 adenine transport 6.708765374774161e-10 1.563526296480941e-09 233.0572332071717 5.952000000000282e-10 5.533517865155531e-10 92.96905015381836 8.25400000000019e-10 3.900580329307424e-10 47.25684915564978 7.224000000000381e-10 4.636606908583504e-10 64.1833735961138 7.879009869952581e-10 4.744222359906035e-10 60.21343339089624 7.562228189837193e-10 4.947134181449262e-10 65.4190016124833 8.358000000000157e-10 3.7903442247199935e-10 45.349895007417125 8.39600000000014e-10 3.740318435160079e-10 44.54881413959046 8.016000000000273e-10 4.067806953467912e-10 50.74609472888938 +r_1109 adenosine transport 5.054000000000214e-10 5.032111726669487e-10 99.56691188502714 3.7260000000001167e-10 4.839587618967563e-10 129.88694629542167 5.138841340602006e-10 5.120869645196865e-10 99.65027728598764 2.9280000000000565e-10 4.568477886346777e-10 156.02725021675857 3.8861689928196276e-10 5.620653772443001e-10 144.63225307052105 5.37400000000024e-10 5.006509465426623e-10 93.16169455575734 5.24400000000023e-10 5.026481582918664e-10 95.85205154306723 6.206894607115799e-10 6.581220785493906e-10 106.03081254108886 4.904000000000205e-10 5.027508246421251e-10 102.5185205224519 +r_1110 ADP/ATP transporter 2.786123703046428 0.046574904376173 1.6716739578090778 5.015461478291162 0.1188070667964465 2.36881625570626 7.8269459851630545 0.1471783016924868 1.8804052304881305 13.138051340479628 0.2409376937475596 1.833892161809468 18.04847511609448 0.4619080517119143 2.5592635873155523 19.46549820888388 0.2841133369000337 1.4595739284513505 25.860567169948133 0.501958760700908 1.9410199219614204 31.47137515241535 0.6659454271768572 2.1160353621400225 30.208676727967845 0.9127151086666996 3.021367393500187 +r_1111 ADP/ATP transporter 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1112 AKG transporter, mitochonrial -0.0375090754708931 0.2438354155265975 -650.070449525776 -0.1130213823899911 0.4905720347338944 -434.0524105793793 -0.0573371993811518 0.6370131919294606 -1110.9946052559762 -0.24315623301814 1.1029232357796537 -453.58624868044114 -0.3743104287564733 1.8942935415806983 -506.0755448021801 -0.1699296162363252 1.5657833967148425 -921.430549538386 -0.2900299253049908 2.252478164417859 -776.63646675397 -0.5932841334516039 3.2698031550936104 -551.1361202381353 -0.3549575070163314 2.5332695318151472 -713.6824779701285 +r_1113 allantoate uniport 1.055462520848105e-09 5.312851503770411e-10 50.33671398868172 -1.864875109276373e-10 7.090642746839824e-10 -380.2207832347125 -1.4464215544683956e-11 7.633938638926856e-10 -5277.810341904483 -2.5420303173024157e-10 8.24926478562747e-10 -324.5148072970872 -4.62023884136954e-12 5.383096040504201e-10 -11651.120700306774 5.998418993903247e-10 9.49184371268168e-10 158.23909137272875 -1.5106028801395455e-11 6.236435447153972e-10 -4128.441385321514 1.5838688520048864e-10 7.193068138778396e-10 454.145438220677 -9.473496284703863e-11 7.779905977181183e-10 -821.2285879863389 +r_1114 allantoin uniport 2.598750189528791e-11 5.155614295942667e-10 1983.8822202750816 -1.3278195640909874e-10 3.852401851883904e-10 -290.12992096717755 -3.7041856318000177e-10 6.109429714930924e-10 -164.93314110616254 -3.0931762492897795e-10 5.131800347903975e-10 -165.9071431536526 -5.430916588864523e-10 5.42184706033957e-10 -99.8330018814218 4.4628878187440565e-10 7.753767343181814e-10 173.73879107191803 -8.062832296192415e-10 6.648132015682945e-10 -82.45405301090605 -6.93254196704578e-10 7.937470785429286e-10 -114.4958201935234 -6.187190154972993e-10 7.160351600726377e-10 -115.72864937682904 +r_1115 ammonia transport 0.1070455079383646 0.0077688262070321 7.257498569211626 0.1815740231102239 0.009403682183463 5.178979912646716 0.6302842683474169 0.0781677005019436 12.401975493834964 0.7890728237926651 0.0483010931603394 6.121246569889594 1.4896039827123713 0.302362358983688 20.29817068783116 1.1952209190399703 0.033015389335117 2.762283424694054 1.8978397551338777 0.2675560717840903 14.097927449370792 2.1110801123803453 0.2361303398554848 11.1852856019394 3.2694417256942696 0.6984241421872406 21.36218354033912 +r_1116 AMP/ATP transporter 0.0005158081973744 0.0042495822147629 823.8686853745577 0.0008953689516506 0.0072780584976766 812.8558047784555 0.0007369847026948 0.0061031249812853 828.1209852754229 0.0010925491567927 0.0089385932954575 818.1410639405473 0.0018838787298401 0.0159590445281986 847.137571830473 0.0017164763447519 0.0145811537205021 849.4817749794878 0.0032045655299625 0.0268564918250425 838.0696719706726 0.0049347911830204 0.0407035023356623 824.827248531089 0.0044640691716878 0.0378571015448833 848.0402092553131 +r_1118 aspartate-glutamate transporter 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1119 biotin uptake 9.987999999999587e-10 4.897999395632864e-11 4.903884056500868 9.851999999999635e-10 1.7025497746458775e-10 17.281260400385108 9.979999999999591e-10 6.322024485773655e-11 6.334693873520955 9.86799999999963e-10 1.6072002421987203e-10 16.28699069921748 9.991999999999587e-10 3.4635241012353085e-11 3.4662971389466093 9.985999999999587e-10 5.09760699931052e-11 5.104753654426927 9.989999999999588e-10 3.7406949300510186e-11 3.7444393694205935 9.979999999999591e-10 5.6538830266161824e-11 5.665213453523461 9.987999999999587e-10 4.8979993956328746e-11 4.903884056500877 +r_1120 carnithine-acetylcarnithine carrier 5.796540285578168e-05 0.001055082992208 1820.194357715644 0.0001218260502074 0.0020505250940447 1683.1581509478094 0.0001176968296551 0.0018581212332862 1578.7351611180106 0.0001766292181785 0.0027850098066269 1576.7548740498012 0.0003018889346942 0.0051401493689776 1702.6623960840318 0.0002690654335175 0.0042484779901797 1578.9757660947305 0.0005622043815853 0.0086726949276014 1542.6231476791268 0.0006815613708047 0.0115209135267389 1690.3706724365013 0.0006303772082784 0.0109956681855703 1744.2997686414944 +r_1121 ceramide-2' (sphinganine:n-C24:0OH) transport 0.0001202080168792 0.0018075982809043 1503.725232169708 0.0001759362792651 0.0029510674042054 1677.3501272911278 0.000162254872192 0.0026274326822021 1619.324367092912 0.0002149551219275 0.0036111804530766 1679.9694841853998 0.0004722197684226 0.0076036484112432 1610.1927364543226 0.0005134518233159 0.0072446041781707 1410.960843684179 0.0007363766972675 0.011692092561924 1587.7868766501922 0.0011713145644259 0.0181504756389836 1549.581657245052 0.0008865454210826 0.0154984030027388 1748.179239797129 +r_1122 ceramide-2' (sphinganine:n-C26:0OH) transport 6.695821521099377e-05 0.0013575085835495 2027.3966073794768 0.0002278329057783 0.0033508211513067 1470.736257284654 0.0001972529517103 0.0028572983251248 1448.5452817557104 0.0002946687070633 0.0042622821015992 1446.4658103930913 0.0005031682981799 0.0079326995987712 1576.5499590226475 0.0005144211956594 0.0072576082181902 1410.8299345805092 0.0007936017142668 0.0122086362320808 1538.3832989019902 0.0013320713110304 0.0194364449127601 1459.1144446857932 0.0015672414760475 0.0206047928635513 1314.7171752699146 +r_1123 ceramide-3 (Phytosphingosine:n-C24:0OH) transport 0.0001425042509571 0.0019332763801071 1356.644708577098 0.0001847470278095 0.002983154928967 1614.7241795104617 0.0002030283413537 0.0028968151321726 1426.8033284699134 0.0003436217826362 0.0046302956356836 1347.4977052269785 0.0005799473537871 0.008518793841584 1468.890889139202 0.0004294487277805 0.0065924041830552 1535.0852748187715 0.0010237185138356 0.0138216505416539 1350.1416995837722 0.0012034582062354 0.0185162485234727 1538.5867517073304 0.0009369688004734 0.0160431987688339 1712.244715163177 +r_1124 ceramide-3 (Phytosphingosine:n-C26:0OH) transport 0.0001113797077351 0.0017379860639426 1560.415356875611 0.0002189245933926 0.0032511699554602 1485.0638318325168 0.0002086494699289 0.0029493343084783 1413.5354906400123 0.0002250863649695 0.0037339061367097 1658.8770880079906 0.0005334472406872 0.0080312371312066 1505.5354154349916 0.0004723267021161 0.0069189310145159 1464.861288493272 0.0009096017964556 0.0129131666205153 1419.6505185931794 0.0013297219040082 0.0192736674316752 1449.4509997599555 0.0013300733076663 0.0190329123781026 1430.9671706363324 +r_1125 choline transport 4.429093339848848e-05 0.0018078342099669 4081.725245439549 0.0001881336425634 0.0050250819885645 2671.017219512017 9.083199382126444e-05 0.003210450905107 3534.4934863198537 0.0002012724463469 0.0058073438865152 2885.3149012289628 0.000267894699227 0.0094686863673837 3534.48067270607 0.0002188825838426 0.007736369191065 3534.483673962605 0.0003020078323145 0.0123269755300628 4081.6741193729326 0.0009167469502828 0.026450982875397 2885.309066720771 0.0007338873070183 0.0231982861216144 3161.0147634064147 +r_1126 citrate transport -0.0015187578987385 0.009247048344526 -608.8559837092038 -0.0035013932474002 0.0248353622851404 -709.2994282656101 -0.1311615704820556 0.0752499199295797 -57.3719265887219 -0.0043166742836941 0.0577771750928758 -1338.4650148639803 -0.5754094037280052 0.2525418968171263 -43.88908057131828 -0.0126754816573286 0.0726968440499046 -573.5233264912929 -0.4709797378860391 0.2536918631243096 -53.86470854627176 -0.3232434944638597 0.2362141616783772 -73.07623068181722 -1.3419502792171776 0.6702637101376441 -49.94698540758457 +r_1127 citrate transport -0.0052036040195815 0.0018701166319442 -35.93887284479828 -0.0085591365412619 0.0016032650909514 -18.73162185487317 -0.0234086327463921 0.0029191679314326 -12.47047601224208 -0.0390438620665965 0.003828058293807 -9.80450726743578 -0.0427175648851997 0.0072635454484343 -17.003650531004162 -0.0591844219041012 0.0072112578109409 -12.18438497654951 -0.0690375188209769 0.0111956780611244 -16.21680247541383 -0.0871159029810305 0.0171509635680712 -19.68752315154885 -0.0918926165263695 0.0156337565318725 -17.013071477169557 +r_1128 citrate transport -0.0298378422412457 0.2443509894959595 -818.9298258242877 -0.0601118488268884 0.3873395943274547 -644.3647997633951 0.0745710768736891 0.6544887236970058 877.6710101767733 -0.1567586227558363 0.99023339452203 -631.693094206623 -0.3641712004898476 1.7663249501738782 -485.0259844265526 -0.2340217739670257 1.5031507679356602 -642.312355151815 0.0364571576943147 2.3067501157042694 6327.290062066439 -0.3659039185761905 3.296846186070137 -901.0141785031608 -0.4218350671260762 2.477514648179401 -587.318324448103 +r_1129 coenzyme A transport 0.0052363757021787 0.0020151894373328 38.48443182742589 0.0083015350779823 0.0023562017631802 28.382723689615595 0.0191722831925381 0.0027480078345864 14.333232025572933 0.028467787538362 0.0039425930030887 13.84931300957573 0.0404847677847243 0.008030123244905 19.83492479839528 0.0477365003856683 0.0074756537447493 15.660246738560147 0.0540314854377249 0.0128568647583206 23.79513473331965 0.0636886063754941 0.0175445369842954 27.547371473096348 0.0719848901848935 0.0181188028416528 25.17028614632123 +r_1130 CTP transport 0.0002988392716943 0.0024246769829221 811.3649083586075 0.0006090893166213 0.0046743689754782 767.4357188543415 0.0004527122407563 0.0037171788986544 821.0908749548951 0.0006587965779743 0.0054478728360059 826.9430986962531 0.0013222111643801 0.0108843963870487 823.1965271713126 0.0009787272271118 0.0084961172364661 868.0781530455045 0.0021401972436293 0.0169750437479252 793.1532384902557 0.0025937848720278 0.0230268298908195 887.7694576426857 0.0022721350602965 0.0211776313860852 932.0586507441756 +r_1131 CTP/CMP antiport 7.440519634869293e-06 0.0003700517810951 4973.466898211877 6.735027955981868e-06 0.0004762294109552 7070.934435131953 5.7138615462458e-06 0.0004040255284037 7070.971621095221 8.441046514205152e-06 0.0005968689259666 7071.029936420801 1.6820502230249076e-05 0.0011893858492396 7071.048372745565 3.2449318882756825e-11 2.054688347911842e-09 6331.992222504487 7.62025071188358e-05 0.003094367557419 4060.7162079240816 3.831776037701454e-05 0.0027094741830231 7071.06614886716 5.78432927482937e-07 3.97884323075732e-05 6878.659636600116 +r_1132 cytidine transport 7.855227234414562e-11 6.33345657577816e-10 806.272866051619 7.760618123978617e-11 5.727907458998788e-10 738.0736131443967 -1.0342148100195847e-11 6.668572999424088e-10 -6447.957363226897 4.6645385356034194e-11 5.580426213967397e-10 1196.3511870195102 -1.405350418466859e-11 6.240665732241195e-10 -4440.647435853994 6.033294831115866e-12 5.745283971886e-10 9522.630888607517 -9.408516946506262e-13 6.130662961085616e-10 -65160.779280544986 8.672853760418222e-11 6.190765329402143e-10 713.8094911338171 -3.679399581843211e-11 5.785131460928981e-10 -1572.303125074253 +r_1133 cytosine transport -9.807927194690756e-11 1.0243932090333287e-09 -1044.454336475759 -7.459242063412872e-11 1.039598048158631e-09 -1393.7046677407034 -9.498169887658554e-11 9.798950443991487e-10 -1031.6672116724037 -5.7331246163207646e-11 9.551552155958626e-10 -1666.0290496333807 -1.0340178940705162e-10 1.1052016798711258e-09 -1068.8419283735868 -1.1459595094759394e-10 8.50599742722821e-10 -742.2598579524073 -9.371005539397092e-11 1.054271721064457e-09 -1125.035853017206 -8.954896009512705e-11 1.1978048400707835e-09 -1337.5977105690183 -2.4775054591156477e-10 1.658669646250706e-09 -669.4918229737312 +r_1134 D-fructose transport 1.1892059019656692e-09 2.056590749890936e-09 172.93815532630163 2.0979999999999968e-10 4.889087505386644e-10 233.03562942739043 2.3000000000000043e-11 6.168850050227144e-10 2682.1087174900576 1.0540000000000051e-10 5.15309565979277e-10 488.90850662170254 -7.560000000000057e-11 5.369751469683518e-10 -710.2845859369678 1.0395999999999744e-09 5.724485823861376e-10 55.064311503092725 -2.0999999999999992e-11 6.540982868910261e-10 -3114.7537471001265 -1.7699999999999815e-10 7.996242115993852e-10 -451.7650912990923 1.0940000000000034e-10 5.350597142184743e-10 489.08566199129126 +r_1135 D-galactose transport -6.5999999999999985e-12 1.2553721328109792e-10 -1902.0789891075444 1.7999999999999986e-11 2.3682740011133013e-10 1315.7077783962795 -1.6e-12 6.927048202470825e-11 -4329.405126544266 -7.000000000000001e-12 1.1727638615744528e-10 -1675.3769451063608 -1.0000000000000002e-12 6.782270994289086e-11 -6782.270994289085 -3.7199999999999947e-11 2.6120835737241555e-10 -702.1730036892902 -2.5799999999999972e-11 2.0770890351094186e-10 -805.0732694222562 -2.6e-12 8.120688955859776e-11 -3123.3419060999145 -1.4e-12 5.829853980974579e-11 -4164.181414981845 +r_1136 D-lactate transport 5.092000000000219e-10 5.027583049365226e-10 98.73493812578576 1.4519999999999938e-10 3.5572780106942086e-10 244.99159853266005 9.340000000000087e-11 2.9102126842506664e-10 311.5859404979271 9.400000000000088e-11 2.9526502719973714e-10 314.1117310635472 3.7000000000001134e-10 4.882086332029631e-10 131.94827924404 5.3565516247841586e-11 9.156311170177043e-10 1709.366736579524 5.200000000000225e-10 5.060150296602231e-10 97.31058262696178 6.238000000000306e-10 4.910415301752892e-10 78.7177829713474 3.1540000000000736e-10 4.736746916848166e-10 150.18221042638095 +r_1137 D-lactate transport 0.0013814511462777 0.0228656711677606 1655.1921672634692 0.0048475415872363 0.0559737811093302 1154.6838763943815 0.0040117163326842 0.0726029135037928 1809.771865280788 0.006831369949426 0.1113483984910679 1629.9570849683478 0.0055173469112809 0.1185247283878097 2148.2196115939187 0.004989527519057 0.1241050189206034 2487.31003981031 0.0141974078550863 0.2299636209408451 1619.7577986636356 0.0405566990165692 0.3278590337244877 808.3967425222224 0.0163159222203343 0.263233844478288 1613.3555978234697 +r_1138 D-lactate/pyruvate antiport -0.0012966735858562 0.0228761336308282 -1764.2168299219218 -0.0047232111744157 0.0558514170001916 -1182.4882466132838 -0.0039545778475517 0.0725950741035714 -1835.7224690497724 -0.006554304478498 0.1108207525491761 -1690.808733599916 -0.0053435392594584 0.1186034800031529 -2219.567860256985 -0.004752853766016 0.1242496509774949 -2614.2115262604225 -0.0134941636301514 0.2296281185747356 -1701.6847050946765 -0.0398958369341741 0.3278068934365122 -821.6568911121599 -0.0158080405379138 0.2632648384570454 -1665.3856486870354 +r_1139 D-mannose transport 8.593638406801562e-11 1.3389797153810355e-09 1558.1057195998385 1.7260818273328223e-10 4.5251461577684947e-10 262.1628990069865 2.600000000000001e-12 5.09289578898884e-11 1958.8060726880149 2.239999999999997e-11 1.4799533953508704e-10 660.6934800673538 3.200000000000001e-12 6.317086442041264e-11 1974.0895131378943 6.438250228634859e-11 2.7002958251915104e-10 419.4145504288781 2.800000000000001e-12 5.2846178137199376e-11 1887.363504899977 3.8e-12 6.153305829757655e-11 1619.2910078309617 5.599999999999999e-12 7.463078420323796e-11 1332.692575057821 +r_1146 episterol transport -2.408069650141304e-07 1.7087017677809992e-05 -7095.732333492654 -2.5982214396319065e-07 1.843246143669014e-05 -7094.261157086554 -1.205559987605323e-06 3.979115286485135e-05 -3300.6364904239176 -1.3566034285824885e-06 4.989759166357433e-05 -3678.126607398612 -9.32459102949444e-07 6.598903534383354e-05 -7076.882528692663 -7.271036085783677e-06 0.0001818781783152 -2501.406624439857 -5.622901188844505e-06 0.0001987630146351 -3534.8836474223986 -4.152187066949798e-06 0.0002077124743812 -5002.483535352981 -7.938936521309542e-06 0.0002807717593043 -3536.6419488398096 +r_1147 ergosterol transport -1.9230642693779018e-06 4.7819943390544114e-05 -2486.653418297535 -3.5943938381501626e-06 6.733723263032255e-05 -1873.396062379668 -4.862111921182241e-06 8.584205595311377e-05 -1765.5302334595572 -7.425116498951664e-06 0.0001271579240667 -1712.5377640157833 -1.169691348599684e-05 0.00022914472454 -1959.0187173251395 -8.403767049902035e-06 0.0001882747060467 -2240.360839713793 -1.3336902780067178e-05 0.0002983187850831 -2236.7920798595965 -2.230809541754913e-05 0.0004748289075747 -2128.504915759114 -1.9554100894056804e-05 0.0004369970260079 -2234.810121802993 +r_1148 ergosterol transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1149 ethanolamine transport -4.756000000000192e-10 5.167765973903231e-10 -108.65782115018968 -3.722000000000116e-10 5.088407843213442e-10 -136.71165618520374 -3.0920000000000675e-10 4.968347098842593e-10 -160.68392945803632 -2.5440000000000276e-10 4.566424689720627e-10 -179.49782585379631 -3.6500000000001104e-10 5.12471975336316e-10 -140.403280914055 -4.2420000000001555e-10 5.19141851185524e-10 -122.38138877546088 -3.030000000000064e-10 4.712063317501224e-10 -155.51364084162137 -1.875999999999981e-10 4.015451253564545e-10 -214.04324379342145 -1.7559999999999844e-10 3.9597474565916485e-10 -225.49814673073368 +r_1151 fadH2 transport 2.313042252072005e-09 2.7163752429587292e-08 1174.3733779724175 2.587823360944711e-09 3.396696768247625e-08 1312.5690182376384 8.567846836785495e-09 9.006079417987538e-08 1051.1485078515318 1.0471271573265376e-08 1.1966933397983437e-07 1142.8347850834746 1.861079048063721e-08 1.968885641481081e-07 1057.9269287511042 2.194228710895445e-08 2.19920349603938e-07 1002.2672135859092 1.690698035910032e-08 2.3328300741598414e-07 1379.8029125314365 2.7248295710112237e-08 3.2172088576295617e-07 1180.7009479993312 3.6019279065996995e-08 3.709694122391304e-07 1029.9190374116451 +r_1161 fecosterol transport -7.349290436062684e-07 3.0039750853656453e-05 -4087.43553068097 -1.0082409905577534e-06 3.567346998916348e-05 -3538.1888182734087 -9.50619066941167e-07 3.883262776836047e-05 -4084.983051445968 -9.1418656043508e-07 4.574794145297584e-05 -5004.223802109217 -4.675792342998824e-06 0.000147827519526 -3161.5501434194825 7.66395430107124e-10 1.3188946692162039e-09 172.0906228566438 -4.3080121256668656e-06 0.0001687885710635 -3918.0152269744617 -2.133000786210125e-06 0.0001508813913353 -7073.667872546798 -2.049013195133396e-06 0.0001449432064821 -7073.805421379713 +r_1162 fecosterol transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1164 folic acid transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1165 GDP-mannose antiport 0.0002037706048308 0.0038487198036012 1888.751229254452 0.000214609378415 0.0053615214382578 2498.2698695906806 0.0001580284276662 0.0042211809376571 2671.152905837458 0.0003006227764615 0.0070804107482235 2355.247606838723 0.0004018426874006 0.0115944044083302 2885.3092943729785 0.0004377542193405 0.0109361564683719 2498.2412470740446 0.0009026864168597 0.0212606079427944 2355.259539271161 0.0012195636729266 0.0304682461519379 2498.290727110749 0.000880665323509 0.0254099044924004 2885.307711578042 +r_1166 glucose transport 0.3730299360838871 0.0130783385259242 3.5059755962811545 0.5695554500263653 0.0095599353883381 1.678490722526769 1.3101497120401149 0.0435648664243975 3.325182307337988 1.8564468044982183 0.0091578214692232 0.4932983507544446 2.705567238071132 0.1202915562647516 4.446075284032142 3.128006167774593 0.0481914658896153 1.5406448486609268 3.593461172180393 0.1337057039829796 3.720805584824266 5.565805480213094 0.2416887388268954 4.342385656238244 7.674218123681864 0.2734458369473695 3.563175199614711 +r_1167 glutathione transport 5.436281655976648e-10 8.01574897276678e-10 147.4491109921479 3.0590376690139904e-10 7.305354936995283e-10 238.81219283416 1.7697799979999843e-10 1.267208876586041e-09 716.0262168281395 6.396000000000317e-10 4.805809313802606e-10 75.1377316104185 3.8320000000001244e-10 4.874477213570716e-10 127.20452018712312 3.3660000000000885e-10 4.72594021356387e-10 140.4022642175801 3.605695611917271e-10 4.961109464917261e-10 137.5909116820671 5.017928856696611e-10 5.008535951998196e-10 99.8128131153976 5.787774493943167e-10 4.946377095581047e-10 85.46250550634562 +r_1168 glutathione transport -4.4293320414223593e-05 0.0018078953936525 -4081.643409763472 -8.062904742063384e-05 0.0032910085461389 -4081.666163026941 -2.270815311215336e-05 0.0016057089053825 -7071.067811865326 -0.0001006364340592 0.0041076432766728 -4081.666163027077 2e-13 1.4142135623730835e-11 7071.067811865417 -0.0002434393240419 0.0079136421191729 -3250.765729947409 -0.0003020082322286 0.0123269678244325 -4081.6661630274807 -0.0004554830264894 0.0185918965688981 -4081.797890954007 -0.0002935552521231 0.0146762944628578 -4999.499874967782 +r_1169 glycero-3-phospho-1-inositol transport -4.381675829799332e-05 0.0005637492362709 -1286.6064450432268 -4.281792997193235e-05 0.00059784023124 -1396.2380517507138 -8.438422920466577e-05 0.0010103394498496 -1197.3083825879348 -0.000110437387846 0.0014004420594812 -1268.086910416136 -0.0002181280113576 0.0028109958712826 -1288.690917680146 -0.0001936415818588 0.0023207444977355 -1198.4742509629243 -0.0004072184039213 0.0046852959901513 -1150.560963118019 -0.0005387302455927 0.0067317678412796 -1249.5618904546036 -0.0005209376560945 0.0064927745101359 -1246.363059797276 +r_1170 glycero-3-phosphocholine transport -6.10203193415613e-07 4.320433204201942e-05 -7080.318901673249 -8.925773712090758e-07 6.31702984689497e-05 -7077.291056951162 -7.86931203187526e-06 0.0002102359401692 -2671.592374500418 -4.785756435376848e-06 0.0001955292144848 -4085.6490948730025 -3.3339906450243205e-06 0.0002357963449231 -7072.495697464006 -5.299344740109753e-06 0.0002649765326887 -5000.175411936398 6.030785965654591e-10 1.2845317193574255e-09 212.995739970354 -7.588666846131956e-06 0.0005366372849017 -7071.562051445638 -1.4594204131379051e-05 0.0007296621892578 -4999.670983695767 +r_1171 glycerol transport 5.905238987558756e-05 0.0020872510145828 3534.575008700473 0.0001343773812224 0.0042476914306467 3161.01667706571 0.0001281436428324 0.0037316944270605 2912.1182639860963 0.0002012728655547 0.0058073442304597 2885.309062626128 0.0004018428624949 0.0115944051732439 2885.308227513536 0.0003086329623498 0.0089937036237356 2914.0450699951275 0.00060401634808 0.0174277341032125 2885.308346141402 0.0010695381038965 0.0285674593316818 2671.009029748916 0.0010270657592924 0.0274330252151132 2671.0096181194112 +r_1172 glycerol transport via channel 0.0001070550282316 0.0021974388630165 2052.6255509090065 0.0001423777842325 0.0042568396607701 2989.8201350132863 0.0001470198627944 0.0037554958199133 2554.413906075542 0.0002172721021694 0.0058205294705919 2678.9124846103755 0.0004198430028687 0.0116015289470378 2763.301726542192 0.0003416243613718 0.0090104147640071 2637.52114393249 0.0006380166991738 0.0174362767223586 2732.8872026290483 0.0010775385133653 0.028568559077109 2651.279626923345 0.0010390659558551 0.0274347607518521 2640.329095305094 +r_1173 glycine transport -0.0043641519566217 0.0070881905331765 -162.41850887940947 -0.0084107485605752 0.0067402003776268 -80.13793693965567 -0.1681960865576378 0.0779158027053819 -46.32438500801955 -0.0279408145651321 0.0475238637688323 -170.08761021641158 -0.6310941597215701 0.3014952650199896 -47.77342023779861 -0.0296659494788009 0.0312503023706935 -105.340644475326 -0.5534611574205959 0.2663579552815437 -48.12586244044736 -0.4351562834510379 0.2358245312795252 -54.19306585884546 -1.4780605885421418 0.696561506928685 -47.12672216067447 +r_1174 glycogen vacuolar 'transport' via autophagy 2.6574604824376407e-05 0.0010847380111855 4081.859423138324 4.83144232356426e-05 0.0019720378062524 4081.675148297357 5.449929645899987e-05 0.001926270013999 3534.486019371215 2.012683513517714e-05 0.0014232140739031 7071.226371878582 0.0003113220324675 0.0078050481220213 2507.0657737131824 0.0001969944907889 0.0056839077012955 2885.3130250146414 0.0001812047490352 0.0073961812136618 4081.6707360261767 0.0006263443933106 0.0167599866023337 2675.842041747472 0.000598767558827 0.0160337695734572 2677.7953042190056 +r_1175 GTP/GDP translocase 1.1073256835799524e-05 0.0007829983220885 7071.075237387307 8.062903978233609e-05 0.0028498115187312 3534.472848026593 6.805328316886231e-05 0.0024053274300259 3534.4766894750733 5.031840716801086e-05 0.0025156614408566 4999.4854416932985 0.0002511518596586 0.0079389410447045 3161.012247926367 0.0002050335461716 0.0064811423206168 3161.015571174108 7.550205251093832e-05 0.0053388013748341 7071.067868069842 0.0004571237678962 0.0161570969003072 3534.5125401518103 0.0004403327749427 0.0155634424732777 3534.4728711826697 +r_1176 guanine transport 7.156000000000372e-10 4.5602437615367556e-10 63.72615653348962 5.551900078452678e-10 5.443195422597957e-10 98.04202787660728 6.362000000000315e-10 4.873367002513873e-10 76.60117891407783 6.406383049882803e-10 5.007485053855433e-10 78.16399698339988 7.300000000000383e-10 4.489324092350832e-10 61.49759030617255 6.48445459092031e-10 4.811280472844875e-10 74.19714958882969 7.310466114863266e-10 4.60404403719796e-10 62.978802785738274 6.332643812607604e-10 5.077155890710949e-10 80.1743480440647 7.591930888543147e-10 4.3463242009547247e-10 57.24925930916584 +r_1177 inositol transport 5.536000000000253e-10 4.987752954578618e-10 90.0966935436848 5.420000000000244e-10 5.002859754295036e-10 92.3036855035943 6.770000000000345e-10 4.685241754494587e-10 69.20593433521933 4.838000000000201e-10 5.013859168021376e-10 103.63495593264098 6.581321662377094e-10 4.858466095881416e-10 73.82204282242296 6.86800000000035e-10 4.659926929019014e-10 67.84983880341842 4.694000000000189e-10 4.99513305837339e-10 106.41527606248806 6.102934080125202e-10 9.92263433388925e-10 162.5879323554104 6.687473128061961e-10 4.789192583161553e-10 71.61438246480805 +r_1178 iron (II) transport 1.4648869034901352e-05 0.0001439642008957 982.766659683918 9.130916687013204e-06 0.0001060044913905 1160.9402979370598 1.70335578353058e-05 0.0001678545572736 985.4345104916548 1.781343618359452e-05 0.0002030933898471 1140.1134949705531 5.079806042469869e-05 0.0005130157493933 1009.9120814933514 4.507729077978233e-05 0.0004661299012657 1034.068137641565 4.787220384359442e-05 0.0005824691809608 1216.7168715772625 0.0001020024408182 0.0011187936343705 1096.830257586241 0.0001023385553786 0.0010814225039505 1056.710738146393 +r_1179 iron (II) transport 1.3958300027697393e-05 0.0001439643071457 1031.3885420150002 8.005870425168122e-06 0.0001060046016239 1324.0859018993854 1.4420959896678798e-05 0.0001678546895839 1163.9633615696166 1.3929740261216104e-05 0.0002030935407581 1457.9851235533924 4.5321988490550056e-05 0.0005130161875274 1131.9366263782815 3.858686306299114e-05 0.0004661301890677 1208.0022890349371 4.060589021861432e-05 0.0005824694980955 1434.4458278333525 9.34688550121009e-05 0.0011187945451572 1196.970418662359 9.266253276387528e-05 0.0010814234121756 1167.055745099601 +r_1180 isoamyl acetate transport 3.00551439968675e-05 0.000867177218328 2885.2871855095395 1.1903058752903195e-05 0.000347545223083 2919.7975940286133 1.3370242619708243e-05 0.0005457284926638 4081.664844730789 3.238450417219912e-05 0.0009343922788889 2885.306731640678 2.6288788417819488e-05 0.0013143076339863 4999.498695403614 1.8204910492443603e-05 0.0010123216500618 5560.706549378493 0.0001185096829893 0.0034193692443564 2885.3078989871665 5.99741161943626e-05 0.0029984054878992 4999.499247612278 5.760374706167921e-05 0.0028798990646271 4999.499531763883 +r_1181 isobutyl acetate transport 3.937937739591677e-05 0.0010629274247474 2699.1981464330133 1.04290842546694e-05 0.0003686097732753 3534.440457802585 2.267258038138728e-05 0.0008013572873004 3534.477654595812 2.789989699596347e-05 0.0009427805091496 3379.154085357616 5.023043519496592e-05 0.0020502365927756 4081.662013912038 3.447919340937317e-05 0.0017237869674911 4999.499109577487 0.0001623522695679 0.0044251599286588 2725.653260305917 7.639561086602784e-05 0.0038193981067658 4999.499399859181 6.831403631806003e-05 0.0034247741943154 5013.280401658963 +r_1182 isopentenyl diphosphate transport 7.79046506986089e-10 6.974006594128071e-10 89.51977233180254 7.78049561435887e-10 1.5891183945195456e-09 204.2438519709251 8.207892748286725e-10 1.3643281506059452e-09 166.22148856546983 7.330999999712831e-10 4.960255799363303e-10 67.66138043319611 8.003396187146611e-10 5.695663929675489e-10 71.16558766418034 8.021174790426017e-10 4.4478519724486656e-10 55.4513782414712 5.917442184932999e-10 9.39119004039365e-10 158.70353688128148 7.400836757657532e-10 5.252031052291196e-10 70.96536816403905 4.370672707783165e-10 8.692943578800917e-10 198.89257695550577 +r_1183 L-alanine transport 3.0200000000000635e-10 5.122972669241444e-10 169.63485659739533 1.0740000000000055e-10 5.512948623060562e-10 513.3099276592676 -9.740000000000086e-11 3.5261609098499243e-10 -362.0288408470116 3.3600000000000887e-10 6.462101186947526e-10 192.32444008771893 -4.379999999999988e-11 3.0512322106979444e-10 -696.6283586068386 4.3120000000001605e-10 5.608292662595179e-10 130.06244579301878 -1.4959999999999926e-10 4.1863455540388247e-10 -279.8359327566073 -6.040000000000015e-11 5.317973313964156e-10 -880.4591579410833 -5.920000000000012e-11 2.9413034956036235e-10 -496.8418066898004 +r_1184 L-arganine transport 4.739999999999986e-11 2.1900418390183747e-10 462.0341432528231 4.770000000000192e-10 5.007206249285391e-10 104.97287734350502 1.2400000000000004e-10 3.3263512927207555e-10 268.25413650973826 9.460000000000088e-11 2.94054643946889e-10 310.8400041721842 2.176e-10 4.126551791258269e-10 189.63932864238367 4.0720000000001427e-10 4.921753826853475e-10 120.8682177518002 1.1180000000000042e-10 3.176805694228552e-10 284.1507776590823 9.691459878553828e-11 5.893144921906508e-10 608.0760789143245 5.218000000000226e-10 4.995744938795146e-10 95.74060825593962 +r_1185 L-arganine transport -8.056779998146293e-12 5.385322769860693e-10 -6684.212267307476 3.1799999999999925e-11 2.0493208492542878e-10 644.4405186334254 3.119999999999993e-11 1.9450996587672003e-10 623.4293778100016 9.800000000000008e-12 1.6765912416681442e-10 1710.8073894572883 4.2e-12 1.9542261383883648e-10 4652.919377115154 4.999999999999999e-12 1.3776355018345844e-10 2755.2710036691697 1.260000000000001e-11 1.4712433216101378e-10 1167.653429849315 4.019999999999989e-11 2.1770034149661183e-10 541.5431380512747 9.980000000000076e-11 3.08316350189809e-10 308.93421862706083 +r_1186 L-asparagine transport 2.9399999999999926e-11 3.2335205474879603e-10 1099.836920914275 1.7137429665800778e-10 5.207548151495426e-10 303.86984822394567 -4.6506112781691037e-10 9.838693170596783e-10 -211.5569885787181 4.268000000000159e-10 5.09012356152326e-10 119.26250144149652 -2.0580000000000277e-10 9.679017133704091e-10 -470.3118140769662 6.200000000000033e-11 4.33351541720726e-10 698.9540995495544 -8.972884624499482e-11 8.064955980986266e-10 -898.814185013121 -2.7653807309771606e-10 9.046414353103135e-10 -327.1308811755023 -5.079999999999975e-11 9.282196282861507e-10 -1827.203992689282 +r_1187 L-asparagine transport 1.108000000000004e-10 3.7222448900366734e-10 335.9426796061968 3.000000000000001e-12 8.362056254113328e-11 2787.352084704442 0.0 0.0 6.000000000000003e-13 3.741550459364175e-11 6235.917432273624 3.000000000000001e-12 5.469550547955539e-11 1823.1835159851792 2.0000000000000004e-12 4.468108413921944e-11 2234.0542069609714 1e-12 3.161012242887019e-11 3161.0122428870186 0.0004583734586246 0.0187092779150809 4081.666938399931 7.669297055729491e-11 2.6833546997261656e-10 349.88274417164695 +r_1188 L-aspartate transport 2.111999999999996e-10 4.324719255550506e-10 204.76890414538423 2.6300000000000333e-10 4.5019055332923187e-10 171.17511533430653 1.477999999999993e-10 3.588605804253601e-10 242.8014752539661 2.4620000000000216e-10 4.3545778750292205e-10 176.87156275504395 1.3539999999999968e-10 3.5537599584058736e-10 262.46380785863226 2.5680000000000293e-10 4.391951029641321e-10 171.02613043774423 2.1659999999999998e-10 4.1390663650240517e-10 191.09262996417604 0.0004583737618246 0.01870927791582 4081.6642386652015 4.202929705573067e-10 5.64158444373757e-10 134.22980727602592 +r_1189 L-aspartate transport 8.040000000000057e-11 2.7704005168577157e-10 344.5771787136438 9.940000000000079e-11 3.0714574342085755e-10 308.9997418720876 1.3599999999999966e-10 3.4860910151793264e-10 256.3302217043629 1.5159999999999915e-10 3.631030277507208e-10 239.51387054797016 2.5640000000000286e-10 4.493321932423475e-10 175.24656522712266 1.4179999999999947e-10 3.573769769595188e-10 252.02889771475324 1.5979999999999895e-10 3.7508945389025697e-10 234.72431407400464 2.2700000000000072e-10 4.2744302720747887e-10 188.30089304294168 3.3540000000000884e-10 4.759749472714865e-10 141.91262590085694 +r_1190 L-aspartate transport 3.352000000000089e-10 5.356289197456756e-10 159.79383047304933 1.9519999999999828e-10 6.349626725399691e-10 325.288254374987 -2.1720000000000032e-10 8.196087552621615e-10 -377.3520972661881 4.55000000000018e-10 6.403569406216292e-10 140.73778914760527 -4.5160000000000075e-10 1.080690065746689e-09 -239.30249462947023 2.942000000000061e-10 6.063991292711443e-10 206.1179909147288 -7.570000000000106e-10 1.0110170280891494e-09 -133.55575007782497 -4.3456548172555274e-10 9.212646445826863e-10 -211.99673773548943 -6.083999999999969e-10 1.171376909783098e-09 -192.5340088400894 +r_1191 L-carnitine transport -8.406000000000137e-10 4.3775560075592246e-10 -52.07656444871702 -7.502000000000401e-10 5.605914845611861e-10 -74.7256044469683 -1.6119999999999888e-10 9.014305715999971e-10 -559.200106451615 -4.750000000000191e-10 6.078230744040355e-10 -127.96275250610758 -2.009999999999988e-10 8.80428322355781e-10 -438.02404097302815 -8.025999999997112e-10 4.543946906689431e-10 -56.615336490045664 -2.6320000000000344e-10 8.63293006436974e-10 -327.99886262802534 -1.6719999999999868e-10 8.476956279087276e-10 -506.9949927683818 -3.026000000000064e-10 7.982234474972707e-10 -263.7883170843536 +r_1192 L-cystine transport 1.283576599320474e-10 5.973555711457473e-10 465.3836564658376 4.304373335200479e-11 8.313874517135624e-10 1931.494754218015 1.671745838342129e-11 4.127015664384677e-10 2468.686070412139 4.913519311911268e-12 4.822741710226159e-10 9815.249323504138 2.1316936499537143e-11 4.663231166681586e-10 2187.570979902689 1.0075608568913759e-10 4.886544633395105e-10 484.9875419407959 1.5339035127432654e-11 3.915818827322212e-10 2552.8455960825586 3.999999999999989e-11 3.7420316086469255e-10 935.507902161734 2.3179581529383464e-11 3.648844009389899e-10 1574.1630213489673 +r_1193 L-cystine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1194 L-glutamate transport 0.0131896391865871 0.0195249432746243 148.03242907872593 0.0232193174686699 0.0421222879016926 181.41053439029253 0.0541300768714519 0.0337860415353879 62.41639304452315 0.0890381142408636 0.0509775270956195 57.25360148319902 0.1015631698751619 0.0962606992805531 94.77914031126991 0.1384823349531599 0.0936789605628044 67.64686672454668 0.1651546230385887 0.1556523962073069 94.24646633775336 0.2107444819324081 0.2141759078321054 101.62823997488954 0.2221196022042756 0.2128347456132013 95.8198841980028 +r_1195 L-glutamate transport 1.441399999999995e-09 6.02526885482729e-10 41.801504473618095 1.007599999999977e-09 5.600044294398126e-10 55.57804976576277 1.0535999999999681e-09 4.5953158091121676e-10 43.61537404244786 1.136599999999991e-09 6.997416435181976e-10 61.56445922208369 2.1180000000000006e-10 5.132187045380597e-10 242.312891661029 1.366200000000011e-09 7.306191352983841e-10 53.47819757710278 8.448000000000257e-10 8.304522202860165e-10 98.30163592400469 1.086722416879064e-09 5.23778122730438e-10 48.19796799946997 1.22859999999997e-09 5.899251158651297e-10 48.01604394148984 +r_1196 L-glutamate transport 4.239999999999988e-11 2.0545238410985848e-10 484.5575096930639 5.920000000000012e-11 2.360222474688758e-10 398.68622883255966 6.980000000000036e-11 2.5483513923639937e-10 365.09332268824943 7.600000000000049e-11 2.6502461698778927e-10 348.71660129972054 5.720000000000007e-11 2.3224760018040846e-10 406.02727304267177 5.980000000000013e-11 2.3798169479480926e-10 397.9627003257672 5.6400000000000046e-11 2.3158101380120595e-10 410.60463439930095 7.480000000000047e-11 2.6309466691812127e-10 351.7308381258284 4.999999999999991e-11 2.1888257563447435e-10 437.7651512689495 +r_1197 L-glutamine transport 1.2341067092929412e-10 4.557432581461418e-10 369.2899930892132 0.0001341795881302 0.0042414568104504 3161.029832893417 0.0001160899466561 0.0035712100006978 3076.24398456757 0.0002012729909491 0.005807344695526 2885.3074961231305 0.0004015966517018 0.0115873115566596 2885.310798174445 0.0003843449498596 0.0102315464320549 2662.073857296944 0.0003020081969997 0.0123269700587022 4081.667378952952 0.0010635246720048 0.0268279395921084 2522.549809919692 0.0018465593397778 0.0357264052065362 1934.75532775648 +r_1198 L-glutamine transport 8.778106709293021e-10 7.965177888891557e-10 90.73913262479654 0.0001341802727302 0.0042414568266261 3161.0137170857674 0.0001160904952561 0.00357120999088 3076.229438938868 0.0002012737057491 0.0058073447054123 2885.297254203221 0.0004015971912826 0.0115873115494743 2885.3069197184154 0.0003843455236596 0.0102315464425925 2662.0698857553302 0.0003020090687997 0.0123269700373386 4081.655589459273 0.001063525443801 0.026827939597107 2522.547979785328 0.0018465599675778 0.0357264052110648 1934.754670216719 +r_1199 L-glutamine transport 1.6319999999999883e-10 3.722814509154901e-10 228.1136341393951 3.4880000000000985e-10 4.766382242323557e-10 136.65086703908892 2.7940000000000464e-10 4.4919482988902166e-10 160.7712347491103 2.8400000000000496e-10 4.5098190311295544e-10 158.79644475808016 2.552000000000028e-10 4.36475729236402e-10 171.03280926191113 1.89399999999998e-10 3.9237537089672975e-10 207.1675664713485 3.1780000000000753e-10 4.66097210163137e-10 146.66369105195912 2.682000000000038e-10 4.4351787068879837e-10 165.36833359015367 2.1659999999999998e-10 4.1196891105606607e-10 190.1980198781469 +r_1200 L-histidine transport, vacuolar -1.0040752461623827e-09 2.300243521776327e-09 -229.0907509738889 -2.2592404532139874e-09 1.5699707333913262e-09 -69.49108631433594 -2.057783423077468e-09 1.903065271586785e-09 -92.4813199603242 -2.118618960330853e-09 1.694515878336905e-09 -79.982097303249 -1.0087065040818247e-09 1.0179171690525795e-09 -100.91311644501974 -1.896728544410883e-09 1.8004714661623574e-09 -94.9250999289188 -1.969133683691988e-09 1.639564931240673e-09 -83.26326164745724 -2.6263846185401037e-09 2.487534302199049e-09 -94.71325275967251 -6.120391722930641e-10 1.0768426933262452e-09 -175.9434268384734 +r_1201 L-histidine transport 2.5799999999999952e-11 2.918071114247633e-10 1131.0353155998598 -3.164000000000073e-10 5.347412735575349e-10 -169.0079878500387 3.93999999999999e-11 2.519133423747349e-10 639.3739654181105 5.2784934347455034e-11 2.3070659002616277e-10 437.069010084477 4.958849401345323e-11 2.330868875043129e-10 470.0422792454173 2.8399999999999945e-11 2.7642127585327357e-10 973.3143515960356 4.9599999999999905e-11 2.3653970112022444e-10 476.89455871013087 5.0999999999999934e-11 2.2980331136077868e-10 450.5947281583902 7.440000000000045e-11 2.857988386877113e-10 384.1382240426205 +r_1202 L-isoleucine transport 4.43135382570689e-11 1.079801313533762e-09 2436.730073932907 7.857795199600121e-11 3.0576320574699336e-10 389.1208640339132 2.7100000000000403e-10 4.472124772409188e-10 165.0230543324399 4.199999999999988e-11 4.082515570904307e-10 972.0275168819808 -5.700000000000007e-11 3.3730365362821924e-10 -591.7607958389805 1.1840000000000018e-10 3.8782924374583557e-10 327.55848289344164 1.0400000000000064e-10 3.0659876151105137e-10 294.8065014529322 4.896000000000202e-10 5.681165296647025e-10 116.03687288902752 3.6278891532026574e-10 5.331665356183244e-10 146.96329273116064 +r_1203 L-isoleucine transport -2.1760145983546576e-09 1.9242199470262962e-09 -88.42863225647704 5.6390394230727614e-11 4.332007638717528e-10 768.2172997394971 2.722643954548053e-10 4.4841439106550465e-10 164.69813848279676 1.0800000000000052e-10 3.1041145445071473e-10 287.41801338029 2.299999999999997e-11 1.4991829474423207e-10 651.81867280101 1.3299999999999975e-10 3.407847221419406e-10 256.229114392437 1.0400000000000064e-10 3.0659876151105137e-10 294.8065014529322 4.940246717072794e-10 5.586670973678325e-10 113.08485777383504 3.657805118916272e-10 5.488588476886987e-10 150.05141877304655 +r_1204 L-isoleucine transport -2.220328136611723e-09 2.0858188994938484e-09 -93.94192079540372 -2.218755776527316e-11 3.7029206386246284e-10 -1668.9176329358122 1.2643954548012638e-12 4.6497158569907436e-11 3677.4221540693375 6.600000000000026e-11 2.5701597507216517e-10 389.4181440487336 8.000000000000058e-11 3.0003000450073867e-10 375.03750562592063 1.46e-11 2.0879549590883943e-10 1430.1061363619142 0.0 0.0 4.424671707258624e-12 1.9103560231612367e-10 4317.509070847719 2.9915965713600013e-12 3.2664448034972485e-10 10918.734279777238 +r_1205 L-isoleucine transport 4.5380000000001776e-10 5.241378674555283e-10 115.4997504309184 3.12400000000007e-10 5.68569163935962e-10 182.0003725787289 5.8072859936833906e-11 5.571640783928324e-10 959.4224892641108 4.4940000000001724e-10 5.09010273267314e-10 113.26441327710155 -4.1692433578195586e-11 5.91270024817671e-10 -1418.1710542483056 5.413568203581123e-10 5.395497928561782e-10 99.66620398340253 -4.4664660753457316e-14 5.704072009198171e-10 -1277088.3989657625 2.219999999999997e-11 5.65836720475833e-10 2548.8140561974496 5.999999999999998e-12 5.47013569090317e-10 9116.892818171951 +r_1206 L-lactate transport -4.3840000000001655e-10 4.970461255961994e-10 -113.37730967066162 -1.1420000000000034e-10 3.1808583074249114e-10 -278.53400240148005 -1.0980000000000048e-10 3.133106967828329e-10 -285.3467183814495 -4.779999999999986e-11 2.1336416018857283e-10 -446.36853595935867 -1.2800000000000008e-11 1.1592604439708419e-10 -905.67222185222 -1.0380000000000068e-10 3.056865205562265e-10 -294.49568454356904 -2.6360000000000336e-10 4.4649178153937045e-10 -169.38231469626882 -2.5660000000000287e-10 4.4135631759363214e-10 -172.00168261637845 -7.040000000000037e-11 2.5972549252294436e-10 -368.9282564246349 +r_1207 L-lactate transport 4.442000000000169e-10 5.053092394618454e-10 113.75714530883074 2.1259999999999963e-10 4.13080339732392e-10 194.29931313847257 6.474000000000321e-10 4.819955434864401e-10 74.45096439394752 1.8019999999999828e-10 3.8956169172844603e-10 216.18295878382327 1.7750000212335258e-10 3.954427909186391e-10 222.78466827500569 5.748000000000267e-10 5.000549679727262e-10 86.99634098342082 5.51800000000025e-10 5.049433171661085e-10 91.50839383220108 6.418000000000316e-10 4.853244976029879e-10 75.61927354362166 4.822000000000199e-10 5.116009256260464e-10 106.09724712277593 +r_1208 L-leucine transport, vacuoluar 1.6641580182981235e-09 1.321252848203537e-09 79.39467488518527 9.93849349548456e-10 2.634585270372952e-09 265.0889967951326 1.060118134026044e-09 4.835818706196515e-10 45.61584743231752 7.949449490569184e-10 8.151535786231312e-10 102.54214201753057 8.001840016791614e-10 4.258819581120515e-10 53.22300336152076 7.2713478099117e-10 3.2335094839774285e-10 44.469190148898896 7.045278965917485e-10 5.108585039102293e-10 72.5107559802214 9.077804598298638e-10 5.827612565394511e-10 64.19627677915346 7.727149040515781e-10 8.59959567812779e-10 111.29066662280624 +r_1209 L-leucine transport, vacuoluar 5.254654961806115e-10 7.499699592410554e-10 142.72487245923332 3.128110078543803e-11 4.3015751355713664e-10 1375.1354739964377 2.4286362534250307e-10 4.3428989994990736e-10 178.82047973937705 8.157405256043853e-11 3.087652105487384e-10 378.50909800021657 6.745668828759896e-11 4.4540469070463736e-10 660.2824745941749 -8.749086011122976e-12 2.871564619234808e-10 -3282.130974120156 2.1778569489989188e-11 3.268361176526289e-10 1500.7235337603947 2.4824817039628456e-10 5.181677098129813e-10 208.72971953260225 1.6848077021662587e-10 6.677762565293251e-10 396.35161666861165 +r_1210 L-leucine transport, vacuoluar 2.1027728719818582e-10 7.45519207544913e-10 354.54100510734804 7.937212868496719e-12 2.7412107560713843e-10 3453.618797287668 3.542113268173411e-11 1.898357915445444e-10 535.9393592809597 3.7789774933209313e-11 2.3521293030645117e-10 622.4247980364345 2.8658425587591648e-11 3.5724299790784286e-10 1246.5548633017709 7.35849308711438e-11 2.7485605027864277e-10 373.5221967660054 7.619725389419605e-11 3.094397801545682e-10 406.1035855494764 8.063552000114596e-11 3.0263700191811787e-10 375.31475200236446 1.1140616780315652e-10 5.811569567819171e-10 521.655998264623 +r_1211 L-leucine transport -4.912000000000206e-10 5.546026296505825e-10 -112.9077014760911 -8.940000000000077e-11 4.126035486246707e-10 -461.5252221752428 4.676343729189922e-11 2.6040531950870576e-10 556.856669631117 5.6400000000000046e-11 2.3244321020240187e-10 412.133351422698 5.299999999999998e-11 2.387517549256911e-10 450.475009293757 7.400000000000044e-11 2.9417904116653247e-10 397.53924481963605 8.067802207768806e-11 2.9655664291322215e-10 367.5804578199204 7.740000000000052e-11 2.7968711979101037e-10 361.3528679470394 5.0199999999999915e-11 2.3851905221104584e-10 475.1375542052714 +r_1212 L-lysine transport 4.676279446298398e-10 6.54978026705967e-10 140.0639192391353 3.2140027003651066e-11 3.129262594509604e-10 973.6340900255384 6.135774547554221e-11 3.6301134553992345e-10 591.6308409418714 4.0378154600037696e-11 3.186380245748181e-10 789.1346886232405 -1.9418309070412864e-10 6.212092066431988e-10 -319.90901184579343 -3.903538762219318e-12 3.30864977315387e-10 -8476.026433186411 2.2221665697540547e-11 3.2943030362674544e-10 1482.473492809345 1.954375394663996e-10 5.100322316523347e-10 260.9694294375935 -2.899999999999994e-11 3.0623153911887333e-10 -1055.9708245478414 +r_1213 L-lysine transport 1.1691524546855044e-10 4.0459457303063326e-10 346.05801100547404 -1.7531334233423302e-10 5.499495383905864e-10 -313.6951991606625 5.134741817488944e-11 2.3724114295415516e-10 462.03129852821655 5.6340615133426045e-11 2.330996895282792e-10 413.73295086724136 4.999999999999991e-11 2.389799620981946e-10 477.9599241963903 5.880000000000011e-11 3.3070293752335323e-10 562.4199617744092 5.800000000000008e-11 2.47079358996114e-10 425.9988948208856 1.2320000000000008e-10 3.3112488389994076e-10 268.770197970731 1.405684858746862e-10 5.860607936439485e-10 416.9218939772954 +r_1214 L-methionine transport 2.1199999999999958e-10 4.11691508267528e-10 194.19410767336265 1.777999999999984e-10 3.8860952571017454e-10 218.56553751978515 2.7380000000000416e-10 4.5702881207537216e-10 166.9206764336615 1.4999999999999922e-10 3.6705169307479155e-10 244.70112871652893 2.736000000000041e-10 4.5429540704630414e-10 166.0436429262782 2.9020000000000547e-10 4.57849194797846e-10 157.77022563674618 2.8580000000000505e-10 4.6191019928818624e-10 161.6200837257446 3.37800000000009e-10 4.801429656398992e-10 142.1382373119853 3.3540000000000884e-10 4.805757282740449e-10 143.28435547824455 +r_1215 L-phenylalanine transport 3.2195708339758084e-10 5.179923465133381e-10 160.88863181608454 -2.7734347628272374e-11 3.911620550702274e-10 -1410.38852008719 2.52942544181592e-11 3.2487001179240436e-10 1284.362869218135 5.6169929667559514e-11 2.908715192466636e-10 517.8420570724945 4.3286505738999087e-11 3.2209073747548123e-10 744.090408723596 5.50800000000025e-10 5.450493333223824e-10 98.9559428689829 1.305225288535194e-11 3.5529644246451874e-10 2722.1081723236816 1.8694960645798639e-10 4.730835982073207e-10 253.0540754647901 4.639999999999987e-11 2.9977493724892397e-10 646.0666751054414 +r_1216 L-proline transport 8.460000000000068e-11 2.9573693050820935e-10 349.57083984421644 6.880000000000032e-11 2.586115542414813e-10 375.8888869788957 1.477999999999993e-10 3.6821498673367527e-10 249.1305728915272 1.7056758145565534e-10 3.793097587149152e-10 222.3809210858332 7.940000000000056e-11 2.812675990804194e-10 354.2413086655131 5.4e-11 2.4959258661236516e-10 462.2084937266021 1.4919999999999926e-10 3.6133844674296836e-10 242.1839455381838 2.560000000000029e-10 4.419310586642463e-10 172.62931979071928 1.0060000000000076e-10 3.1128607389980073e-10 309.42949691828863 +r_1217 L-serine transport 7.680000000000049e-11 2.7003026361624434e-10 351.6019057503158 1.7159999999999859e-10 3.895944003182467e-10 227.03636382182395 5.322000000000237e-10 5.073604664620315e-10 95.33266938406784 3.1440000000000726e-10 4.707408622500109e-10 149.72673735687025 5.914000000000281e-10 5.00495893317679e-10 84.6289978555386 3.0640000000000667e-10 4.6104398088518235e-10 150.47127313484737 5.584000000000256e-10 5.010385693033822e-10 89.72753748269328 6.688000000000337e-10 4.74079645526011e-10 70.88511446261766 6.332433956922241e-10 5.427214576497168e-10 85.70503243171541 +r_1218 L-threonine transport 8.080000000000059e-11 2.7692363087947937e-10 342.72726593994724 1.3539999999999968e-10 3.4218453800780277e-10 252.72122452570432 2.2840000000000078e-10 4.198436539222173e-10 183.8194631883607 6.164000000000297e-10 4.863109495661584e-10 78.89535197374022 2.1699999999999995e-10 4.122438465250793e-10 189.97412282261723 7.296000000000383e-10 4.4735205909099384e-10 61.31470108154748 3.954000000000133e-10 4.889853385657595e-10 123.66852265193296 7.924000000000306e-10 4.0562932220121006e-10 51.18996999005482 1.2220000000000008e-10 3.2754941264418517e-10 268.0437092014606 +r_1219 L-tryptophan transport 5.435950380705676e-10 5.255090766549318e-10 96.6728979940968 -2.166213208975719e-11 4.634609262865816e-10 -2139.498200667544 4.087627188776661e-11 3.794318652087992e-10 928.244792603885 4.090519203825701e-12 4.3584856967659046e-10 10655.091638952788 5.640692990614632e-11 3.972612235541976e-10 704.2773365173175 4.6080000000001825e-10 5.590401284103295e-10 121.3194723112646 -1.701263953790459e-11 4.58207514820541e-10 -2693.335821285364 1.2773421606278488e-10 6.065990251039869e-10 474.89157079558606 2.377077560536716e-10 4.949725265348272e-10 208.2273354274012 +r_1220 L-tyrosine transport 6.720000000000342e-10 5.661096148443437e-10 84.24250220897545 8.140000000000058e-11 2.734757718693831e-10 335.96532170685634 -9.013339753260342e-12 2.846391590077111e-10 -3157.9765858127143 1.252e-10 3.321852335759202e-10 265.32366899035173 1.3115945950738901e-10 4.607917006803896e-10 351.32174409001004 6.840000000000033e-11 2.5324744194832643e-10 370.2447981700661 1.0400000000000064e-10 3.052910750875364e-10 293.5491106610908 5.100602626345308e-10 6.148176715010445e-10 120.5382415649138 -4.1689683437393004e-10 6.18374319086868e-10 -148.32789987851655 +r_1221 L-tyrosine transport 7.430000000000392e-10 4.383941581357967e-10 59.003251431463454 8.180000000000061e-11 2.7408718459086624e-10 335.06990781279234 9.083260702203232e-05 0.0032104534743871 3534.4724539376743 1.2096233586842722e-10 3.4352546593668326e-10 283.9937435652215 1.1135873819872116e-10 3.7511405036142236e-10 336.85192238082504 6.860000000000031e-11 2.5279798528522745e-10 368.5101826315252 1.0400000000000064e-10 3.052910750875364e-10 293.5491106610908 5.094322045365549e-10 5.571289805162291e-10 109.36273277482826 -2.1717191110327878e-10 1.0047541133193612e-09 -462.6538064775504 +r_1222 L-tyrosine transport 7.100000000000038e-11 2.6300728995013184e-10 370.4328027466626 4e-13 2.8284271247461228e-11 7071.067811865307 9.083261603537211e-05 0.0032104534812067 3534.4721107191 -4.237664131572901e-12 1.1226127211986278e-10 -2649.130951258154 -1.9800721308668467e-11 3.6852082659341207e-10 -1861.1484947878089 2e-13 1.4142135623729536e-11 7071.067811864768 0.0 0.0 -6.280580979761459e-13 3.2489867857230027e-10 -51730.67262714287 1.997249232706349e-10 7.894298385801736e-10 395.2585514380024 +r_1223 L-tyrosine transport 4.0336834549655336e-10 5.169267206520981e-10 128.1525252101159 2.709834846063692e-10 5.98392814496523e-10 220.82261410349372 1.677839355350693e-11 4.1812659895122286e-10 2492.053828739929 -1.0541937501819476e-10 5.821957385139235e-10 -552.2663537072193 3.056378104928772e-11 3.7405015028016407e-10 1223.8346743714856 5.027301556571499e-10 5.661566836120401e-10 112.61641603177388 -3.678367138350946e-11 4.544946854194313e-10 -1235.5881518210456 5.5994668245479164e-11 5.367203541134856e-10 958.520464413715 4.179999999999989e-11 3.2322384616694067e-10 773.2627898730659 +r_1224 L-valine transport 5.162000000000225e-10 5.182579263799306e-10 100.39866841919958 2.431544239103203e-11 4.2628235993457846e-10 1753.1342966303548 1.3008306586475148e-10 4.263897382316655e-10 327.7826636366232 -2.699999999999995e-11 4.1605963649967694e-10 -1540.9616166654737 8.475646339939252e-11 3.6951346434367517e-10 435.970838710483 3.2794857145823823e-10 5.031096271982102e-10 153.41113545977967 9.869385325326371e-11 4.888234430791358e-10 495.2926924686374 1.2962916160709442e-10 5.177539393625828e-10 399.41162385350697 7.148088058127486e-11 4.4708212503379904e-10 625.456935334561 +r_1225 lanosterol transport -1.2939944689048756e-05 0.0001830214971113 -1414.3916493418983 -7.2986557447268784e-06 0.0001124274986263 -1540.3863746766483 -1.2313965902313264e-05 0.0001811626014122 -1471.196224266194 -2.388654471777037e-05 0.0002989530094091 -1251.5540147868944 -3.991107762243277e-05 0.000554104619724 -1388.3479292791797 -3.877590790249854e-05 0.0005501350578277 -1418.7548082977023 -7.090092773381351e-05 0.0009131308286134 -1287.8968693352258 -7.072845334495622e-05 0.001120373509267 -1584.049213974418 -7.967589511649565e-05 0.0011721644038181 -1471.1656544357631 +r_1226 malate transport 3.4486273552520325e-05 0.0015958815167711 4627.5846949386505 0.0001610149133449 0.0056910410724488 3534.48072245038 4.544101169109084e-05 0.0025392475862705 5588.008479063922 0.0001005360676752 0.0050263030833883 4999.502367272422 0.0002248483261588 0.0101860791858255 4530.200139728532 9.582376425163325e-05 0.0058846159799154 6141.082043554936 0.0003300641780853 0.0152281162081938 4613.683404400317 0.0004420770832095 0.0181837940878795 4113.263224562726 0.0004708705481521 0.0221194686439332 4697.568945592143 +r_1227 maltose transport 8.635349260861517e-10 1.472155415443017e-09 170.48012430896696 8.616000000000064e-10 3.459326146445017e-10 40.150024912314194 8.222000000000202e-10 3.8238253527148734e-10 46.507240971962766 8.710000000000031e-10 3.3523346535698165e-10 38.48834275051441 8.246000000000195e-10 3.8401084993341187e-10 46.56934876708741 8.120000000000239e-10 3.9075124735241624e-10 48.12207479709419 8.248000000000192e-10 3.8070191329877815e-10 46.156876006155336 8.164000000000221e-10 3.871963638837847e-10 47.42728612001153 8.332000000000163e-10 3.7283449560389216e-10 44.74729904031263 +r_1228 N,N'-diformyldityrosine transport 8.228394178414e-06 0.000179639932221 2183.171203589948 3.889066454341255e-06 0.0001374652042437 3534.6581463086777 1.2094555877745574e-05 0.0003230467319769 2671.009462789576 1.902581506259495e-05 0.0004770249573223 2507.251099377032 2.02400513992642e-05 0.0007153790324683 3534.472409958272 1.8457808967426155e-05 0.0005325637142483 2885.302991206508 3.816076271333536e-05 0.0012062663090731 3161.012053492428 0.000103275743367 0.0024323147598469 2355.165579591457 7.759162052979143e-05 0.0020724783142419 2671.007900197501 +r_1229 NAD transport 6.940000025770878e-11 3.4555393375468007e-10 497.9163292096629 1.2998299822737986e-10 1.1282687453611915e-09 868.0125560632983 2.3520154749698648e-11 1.964286901788512e-09 8351.505007906799 -1.3505601713914011e-11 4.05935693348721e-10 -3005.683878049727 -1.2599998180794224e-11 1.7101779591228371e-10 -1357.284290508555 -1.7799798834796344e-11 1.8944534862648936e-10 -1064.3117396144264 -1.2199550758531544e-11 1.5118118971394586e-10 -1239.235712087348 -2.4586605225251337e-11 1.3014111863679172e-09 -5293.171523457501 -1.0400023021948355e-11 1.6339272758968514e-10 -1571.0804413111282 +r_1230 NAD transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1231 NAD transport -6.519999979914582e-11 3.4259660560740416e-10 -525.4549181944822 -1.2998299920240247e-10 1.128268743940086e-09 -868.0125484589006 -1.9520155268122123e-11 1.9622929496830595e-09 -10052.650313123437 1.6105603902241758e-11 3.996320690199039e-10 2481.323093785255 1.459999959901506e-11 1.5871949845412128e-10 1087.1198822829335 2.0199799455831912e-11 1.7606069074211768e-10 871.5962310768734 1.2800000453382336e-11 1.4778540924984814e-10 1154.573468868875 2.6586605240994832e-11 1.2998338192350303e-09 4889.055249636649 1.1199997270685314e-11 1.5836534185962342e-10 1413.97661117406 +r_1232 NAD transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1235 nicotinate transport -1.7451440540558378e-08 1.706204287285487e-08 -97.7686789420133 -1.13731405998202e-08 2.8223762214710106e-08 -248.1615519213426 -6.327633363611656e-10 5.398689627284259e-09 -853.1925472058042 2.011952511706341e-10 6.7208107364421015e-09 3340.4420319752817 -7.730107227569506e-10 8.25557265441651e-09 -1067.976473207632 -6.424422439984459e-10 1.3037887583299188e-08 -2029.425633992202 -8.765666867515825e-10 1.0349907768676833e-08 -1180.7325016003 -1.277995104967286e-09 1.5904104604422192e-08 -1244.457396010863 -5.142024740653544e-10 1.5969799202769376e-08 -3105.741416704977 +r_1236 octadecanoate (n-C18:0) transport 3.4326383527311184e-06 0.0016724337602954 48721.52520712809 8.216117253225088e-05 0.0036524450562722 4445.463646272219 -4.755635135621253e-05 0.0028666590739266 -6027.920545153852 7.264490718631304e-05 0.0041347729787885 5691.758911858829 1.1962491072152582e-05 0.0069779805557396 58332.169392240496 0.0003346570706982 0.0070937964615862 2119.7210764994543 -0.0003435045527314 0.013267944592778 -3862.5236513682166 0.0004289359214723 0.0171598209158277 4000.555807246344 -0.0001885736380259 0.0178675318907882 -9475.095287885852 +r_1237 ornithine transport 0.00312440564599 0.0019966514679592 63.90500127669979 0.0054746023696121 0.0043834382708851 80.06861457585043 0.0143499339320211 0.0048554362609746 33.83594854147704 0.0239043309399121 0.0078884097520724 32.99991860011232 0.026335567712415 0.013354293090009 50.70820282227532 0.0359540102750602 0.0108149342641162 30.07991092336671 0.0424240185469133 0.0203082133598037 47.86961267553304 0.0537932526431609 0.026649939197222 49.541416233008114 0.0568555534385222 0.026923313794912 47.35388570972949 +r_1238 orntithine transport 6.680000000000339e-10 4.722505734467726e-10 70.69619362975283 6.524000000000325e-10 4.762558177290693e-10 73.00058518225711 2.2500000000000052e-10 4.1858098620027056e-10 186.03599386678644 6.188000000000302e-10 4.857301171940676e-10 78.49549405204328 7.316000000000384e-10 4.4317120861357203e-10 60.57561626757089 4.1800000000001505e-10 4.93684864006359e-10 118.1064267957754 2.956000000000059e-10 4.5767076868258816e-10 154.82772959491854 5.440000000000245e-10 4.985114870697967e-10 91.63814100547324 5.476000000000248e-10 4.977788633111727e-10 90.90191075806248 +r_1239 oxaloacetate transport 9.044494886205432e-05 0.0029232302199452 3232.0546992665504 0.0001567252521144 0.0054425893156127 3472.694567202239 4.2675881211539896e-05 0.0024842619637683 5821.23179004587 8.326519181484043e-05 0.0039146013395764 4701.365906033627 0.0001136860758826 0.0071647510870296 6302.223936750087 0.0002704898013442 0.0101953960257898 3769.234912045085 0.0006827384390845 0.0200166995384669 2931.8254828755707 0.0012264436616971 0.0364347023699025 2970.7603787917506 0.0012264737026613 0.0351628515136772 2866.987807188736 +r_1241 pantothenate transport 2.179957468979079e-11 2.0428478928998567e-10 937.104471976954 3.3599961994268494e-11 2.3169312223351827e-10 689.5636437715036 1.560158736355538e-11 1.9226001631963608e-10 1232.3106094239297 4.2192520429136596e-11 2.6537833897625265e-10 628.9701024662943 4.248054294496385e-11 4.6485441458691647e-10 1094.2760670200566 3.4188803050670106e-11 2.502443505894197e-10 731.9482645196463 3.158149952450344e-11 2.8394422306401687e-10 899.0840439470278 4.4673793373757706e-11 6.994758913863339e-10 1565.7409827149806 3.5801625362236933e-11 2.8519777086103406e-10 796.6056512111787 +r_1242 pentaprenyl diphosphate transport 4.3094446046207056e-10 5.88810522895971e-10 136.632577261727 6.07706453430112e-10 5.831596948639239e-10 95.96075400752493 6.381850832511995e-10 1.3304256554819211e-09 208.4701899806462 5.275968332173418e-10 9.98454191424852e-10 189.24567559213187 6.024764476802216e-10 5.244591808068477e-10 87.05056983160557 4.670961656243421e-10 7.885824568777831e-10 168.8265746784128 6.196723599909081e-10 5.149481902451002e-10 83.10007408635354 5.72073674753057e-10 5.192929043357421e-10 90.773780939999 5.784982316154701e-10 8.157884115018643e-10 141.0183068708362 +r_1243 phenethyl acetate transport 1.779951269305774e-05 0.0004538551748345 2549.817979070566 8.213347859834758e-06 0.0002596221673242 3160.9785894229244 1.7869397047198672e-05 0.0005156500296449 2885.659926201935 2.48434261889528e-05 0.0007168450579602 2885.4516784766565 2.6326196656315315e-05 0.0010231113752172 3886.286304755092 7.194890475863155e-05 0.0017974781558502 2498.270351550553 4.645175490053061e-05 0.0016928001920424 3644.2114957063295 0.0001368689856359 0.0036638344083925 2676.891621113661 8.844872593456675e-05 0.0028456035164653 3217.23516805716 +r_1244 phosphate transport 0.0065275377108379 0.0015966376968521 24.460030222440267 0.0106510375990675 0.0026241600629508 24.637600220100204 0.0243546183611377 0.0030676967995074 12.595955124480753 0.0363878321454677 0.0052572990485106 14.447958942685815 0.0512234144016484 0.0082840723805158 16.17243301190257 0.060245512580864 0.0052405503169797 8.698656700689007 0.0680765286206613 0.0125765900883673 18.47419417997516 0.0807395660419178 0.0203234599643416 25.17162397651513 0.0909808608059635 0.0188605466665297 20.730235457712293 +r_1245 phosphate transport 2.3657382221534484 0.1209390971243756 5.112108177982983 4.319482633356516 0.2528545409672463 5.853815431844024 6.219558982975204 0.4185152116780049 6.729017488596964 10.66986699324336 0.6891942223673656 6.459257859575892 14.723746000304027 1.2040551026424815 8.17764108819603 15.473041211463991 0.8501316042216264 5.494276093517821 21.252971696040785 1.3780261670793694 6.483922280553744 25.91299306026437 1.678275177847062 6.476577884862598 24.07667481544193 1.685595022707148 7.0009460842411135 +r_1249 potassium transport 8.245939132069933e-05 6.092562105366698e-07 0.7388560608786977 0.0001343394056084 8.287950669749946e-07 0.616941144872078 0.0003119648196452 8.789783573673548e-07 0.2817556025602411 0.0004637439538888 1.2555132487608642e-06 0.2707341493581375 0.0006538862210835 2.753158831951932e-06 0.4210455493907674 0.0007750083096045 2.257307930933882e-06 0.2912624165391915 0.0008676552124562 4.099385440915579e-06 0.472467102377034 0.0010189775156637 5.981779920081256e-06 0.5870374790541729 0.0011553934898627 5.816982115880564e-06 0.5034632934076398 +r_1250 putrescine excretion 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1251 putrescine transport -3.320836161716268e-05 0.0007820973734462 -2355.121828841124 -1.0551075749215453e-05 0.0003729217181796 -3534.4426202928707 -1.1823268255890003e-05 0.0004825856986823 -4081.660740818738 -2.7954605650056664e-05 0.0008836478096587 -3161.009748162601 -8.039008257674009e-05 0.0021476249637623 -2671.5048609537484 -4.7837197854164885e-05 0.0016907923592129 -3534.471990536499 -0.0001391864662496 0.0034774223013765 -2498.391111632927 -0.0001591048689306 0.0045906643729746 -2885.3072843273376 -0.0001519465825092 0.0043842809576686 -2885.409388790956 +r_1252 putrescine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1253 pyridoxine symport 5.409999999994771e-10 9.76375779057759e-10 180.4761144285956 4.9399999999894637e-11 4.0421815701856645e-10 818.2553785818392 7.06199999998434e-10 1.009398502605707e-09 142.93380099234568 2.723999999987379e-10 7.347831117002041e-10 269.7441672920737 3.22399999998844e-10 7.70049891477347e-10 238.8492219231105 4.4280000001560307e-10 8.480990593183793e-10 191.5309528655137 5.828000000041856e-10 1.0149631471333919e-09 174.1529078802509 5.936000000144518e-10 9.392632661545302e-10 158.23168229980843 6.568000000044008e-10 1.0162776805906243e-09 154.73168096586707 +r_1254 pyruvate transport -5.022000000000214e-10 5.89630980307682e-10 -117.40959384859757 -2.898000000000054e-10 4.811052405144657e-10 -166.0128504190672 -8.200000000000003e-12 1.0832869897402208e-10 -1321.0816948051472 -6.420000000000023e-11 2.801679118167685e-10 -436.398616537021 -9.600000000000006e-12 1.229262468817549e-10 -1280.4817383516126 -1.3499999999999971e-10 5.542891369037205e-10 -410.5845458546089 -9.44000000000009e-11 2.9716376168749005e-10 -314.7921204316603 -4.299999999999988e-11 2.1061783394193427e-10 -489.8089161440346 -1.979999999999998e-11 1.3932638791152578e-10 -703.6686258157875 +r_1255 S-adenosyl-L-methionine transport 4.43800000000017e-10 4.972836395897614e-10 112.05129328295229 2.7960000000000465e-10 4.4929301446000646e-10 160.69134994992814 4.2900000000001584e-10 4.961937541407777e-10 115.6628797530908 2.646000000000034e-10 4.4207004556410176e-10 167.07106786247016 3.5720000000001046e-10 4.808891877368287e-10 134.6274321771597 3.685009934445253e-10 7.436996426515996e-10 201.81754076154408 4.3640000000001645e-10 4.971966219678081e-10 113.93139825109752 5.520000000000251e-10 4.977404435143183e-10 90.17037020186515 4.36704999777637e-10 7.938320075951701e-10 181.7776320397926 +r_1256 S-adenosyl-L-methionine transport -8.970362793790134e-10 7.023094412298444e-10 -78.2922003685323 -9.951999999438692e-10 9.580603195318035e-11 -9.626811892944524 -7.923999999395681e-10 4.080876708304302e-10 -51.500210860872365 -9.963999999754923e-10 7.738370401675906e-11 -7.766329186939222 -9.881999999644684e-10 1.2191690918639742e-10 -12.337270713497368 -6.837999997928373e-10 4.819377684634083e-10 -70.47934609672639 -7.314000000100181e-10 4.5088213420489926e-10 -61.646449849428976 -6.10400000025799e-10 4.91792854830642e-10 -80.56894738038271 -8.914000000122987e-10 3.15635811015968e-10 -35.40899831855656 +r_1257 S-methylmethionine permease 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1258 sodium proton antiporter -0.0006736730342544 0.0083127791079033 -1233.9486197637784 -0.0014275654449817 0.018422368950224 -1290.47456387964 -0.0036284421705363 0.0410230383938865 -1130.5964506476512 -0.0035073388716913 0.0673505453850679 -1920.274825129424 -0.0039061706248317 0.0645965286068403 -1653.7047356865903 -0.034580602307735 0.1871747065203116 -541.2708108859164 -0.0050702472225076 0.0835718994878791 -1648.280563458314 -0.0056948693807108 0.096840209369466 -1700.4816598160269 -0.0164779963741105 0.1912958977271339 -1160.9172218758922 +r_1259 spermidine excretion 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1260 spermidine transport -8.411853316144437e-06 0.0002246794373867 -2670.9861542104745 -3.562894498453716e-06 0.0001454255825299 -4081.6696254421513 -5.812464005115848e-06 0.0002054398690656 -3534.471248076587 -4.184831792016085e-06 0.0002092198452308 -4999.4804003838 -1.285714501030948e-05 0.0005247855486363 -4081.664694732477 -2.647637818297192e-05 0.000763921194188 -2885.29340723572 -1.9325759950331788e-05 0.0007888130128087 -4081.6662052932834 -4.888619540749285e-05 0.0015452980063601 -3161.010983733174 -4.6962130985271697e-05 0.0014844775321269 -3161.00973482772 +r_1261 spermidine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1262 spermine transport -7.090749414545318e-07 5.015648933928237e-05 -7073.510345238815 -2.298758086773543e-06 9.382763916857983e-05 -4081.666518475333 -2.6723275035609617e-06 0.0001090755384165 -4081.668069173714 -2.57410730339969e-06 0.0001286921922905 -4999.488254454929 -1.0498675094003998e-05 0.0003710733320378 -3534.4777194772723 -8.094043311949973e-06 0.0003303787846105 -4081.752121622056 -6.432046949728908e-06 0.0003173244375601 -4933.490691847572 -5.993545204279327e-06 0.0004238089978244 -7071.090371052158 -5.757622903560689e-06 0.0004071280596131 -7071.113659794545 +r_1263 spermine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1264 succinate transport 0.0001464748532518 0.0038898437298314 2655.63927423236 0.0003965426481816 0.0077532427816818 1955.2103203111565 0.0002799585969911 0.0064178804985831 2292.439156203877 0.0003269415430678 0.0073671089949716 2253.3413544949285 0.0010889445457553 0.0222080539975705 2039.4109217164264 0.0008207381339196 0.0176961369281578 2156.124614759256 0.0017278313648692 0.033959137428884 1965.4196653302265 0.0018489721934514 0.0443697287739351 2399.6969197850367 0.0014016247216521 0.0372862403953409 2660.215663961066 +r_1265 succinate-fumarate transport 0.0062359028831098 0.0628344463521244 1007.623876284443 0.0838180031078311 0.1255586478400893 149.79914002312745 0.1715787658742307 0.2078854408829802 121.16035444348788 0.2857012056549958 0.3689245487278987 129.129503630237 0.669141388742538 0.4996984853944062 74.67756348676147 0.0498673352051114 0.4765604262396665 955.6564919290462 0.5888126773182939 0.6917735653955551 117.48618738071151 0.4915964242256291 0.9689395667910432 197.10061323520264 1.519469959201579 1.103119193887495 72.59894723204269 +r_1266 sulfate uniport 0.0023890462773145 0.0018657870643909 78.09756898004736 0.0037986017141732 0.0014238918661221 37.484631800417006 0.0100155725595851 0.0017318703780387 17.29177605908652 0.0164673995426846 0.0024475075325894 14.862744577523234 0.0186411860887077 0.00398818063085 21.394457476425995 0.025413112934277 0.0051641938608405 20.32098103918291 0.0292181343731277 0.0070196617644974 24.025017048841647 0.0363569292162563 0.0094325601624195 25.94432578811401 0.038853716365667 0.0090868038624766 23.38721932532101 +r_1267 sulfite transport 3.9038554130763534e-05 0.0008937751936385 2289.4679722121227 5.049742729154427e-05 0.0012501265794267 2475.6242970739386 8.155731586174131e-05 0.001597547261072 1958.8031364106075 0.000100636909556 0.0021434279958494 2129.8626968037106 0.0001396144855777 0.0035280835421289 2527.018258549485 0.0001986299690018 0.0042367159510864 2132.969144775023 0.0002773317309288 0.0061958540859661 2234.094910530236 0.0003377489927222 0.0084378104306156 2498.2488808057265 0.0003244557002952 0.008105710744966 2498.248832610949 +r_1268 taurine transport 5.4392129962332936e-11 3.9203672722139717e-10 720.7600207840478 9.785999999999658e-10 1.4746657003488356e-10 15.06913652512658 1.6739999999999872e-10 3.7868974264459107e-10 226.21848425602985 9.53770767077359e-10 8.927822390192965e-10 93.60553602990478 1.6748366301326263e-10 4.784807785593696e-10 285.68803067167204 5.4874912974245925e-11 8.773598535759297e-10 1598.8359817312062 1.90599999999998e-10 3.9332248920712254e-10 206.3601727214726 1.1626799949982703e-10 1.5971248137986602e-09 1373.6581180284577 1.6919999999999862e-10 3.7656303581736727e-10 222.5549857076656 +r_1269 thiamine diphosphate transport 1.240657209627912e-11 6.136686167661658e-10 4946.318870384934 -7.0411928364418805e-09 1.909069050970844e-08 -271.12864188158665 2.052053556312263e-09 1.2231676365295135e-09 59.60700356805809 2.132440460601461e-09 1.8070968483903246e-09 84.74313265846718 3.899514846392071e-09 2.9858260754576623e-09 76.5691680394607 3.822190222087406e-09 2.112306581784269e-09 55.26429766833216 5.3757353790492295e-09 4.1052911985287314e-09 76.36706253302977 8.845735319075096e-09 5.027344142275059e-09 56.83353572013405 7.764477063896596e-09 4.368235287997184e-09 56.25923358456015 +r_1270 thiamine transport 2.1740738485764608e-10 8.153282814743882e-09 3750.232688775721 -3.4667673489914566e-10 7.836867286747635e-09 -2260.5691405936186 -6.827126075574425e-11 4.1195689465303637e-10 -603.4118750595576 -1.0526420316698688e-10 4.5363747095320276e-10 -430.9513180217312 -4.28730781903216e-10 1.190542489967648e-09 -277.6899957317288 -8.346800451686123e-11 5.490350298246194e-10 -657.7790292251563 -1.6879209861658948e-10 1.0096345929410315e-09 -598.1527578695565 -1.8647042444251871e-10 1.348827496241286e-09 -723.3466112783343 -1.343729821004927e-10 1.140026138453857e-09 -848.4042853207445 +r_1271 UDPgalactose transport -1e-12 4.2418862219231965e-11 -4241.886221923197 2.600000000000001e-12 7.870501188475425e-11 3027.1158417213164 -6.000000000000003e-13 3.741550459364377e-11 -6235.917432273961 -2.2000000000000003e-12 6.161103134858752e-11 -2800.501424935796 -1.8252789011945258e-12 6.745528676029432e-11 -3695.615323014431 -6.000000000000003e-13 3.741550459364029e-11 -6235.917432273382 -5.199999999999999e-12 8.23062261494931e-11 -1582.812041336406 -1.4e-12 4.688794830166019e-11 -3349.1391644043 6.000000000000003e-13 5.831226341013261e-11 9718.710568355436 +r_1272 uracil transport -1.5644393233238906e-10 9.529697066932535e-10 -609.1445621991422 -4.4001676063842576e-11 6.918049940081818e-10 -1572.2241875614768 -3.9484877781877216e-11 5.540695622896187e-10 -1403.2449722914575 -4.1566860947455325e-11 5.973521566958217e-10 -1437.087485270862 -4.395025396074226e-11 6.898253509052835e-10 -1569.5594194323814 -1.0494057592177392e-10 7.297471719279385e-10 -695.3908586054604 -4.070907474737815e-11 7.057832140901671e-10 -1733.7245281793653 -2.2932946435797117e-10 1.40617012749915e-09 -613.1659232867665 -4.693041057288518e-11 6.859254621601978e-10 -1461.5799303415909 +r_1273 urea transport 1.3725011371783488e-11 3.3903378768207924e-10 2470.1894847175176 -1.5822657336395728e-10 4.4746006884879845e-10 -282.7970418215012 -6.399999999999999e-12 2.365802909094684e-10 -3696.567045460444 7.164971878729595e-12 2.045565732819961e-10 2854.952911807738 -5.426751794213786e-12 2.5001530296831367e-10 -4607.089331686217 4.5367988672052985e-12 3.491695810858025e-10 7696.386622069794 -1.8399999999999983e-11 2.8788542096312086e-10 -1564.5946791473975 -2.179999999999997e-11 3.068282723572603e-10 -1407.4691392534894 1.699999999999999e-11 2.0474223764718728e-10 1204.3661038069847 +r_1274 uridine transport -1.5295710967800044e-10 8.249001011011216e-10 -539.3015746948086 -2.6680377878645625e-11 5.89375819682754e-10 -2209.023509200284 -1.1996348010577366e-10 5.794656829643514e-10 -483.0350723848855 -6.666276714205221e-11 5.899144369937495e-10 -884.9234172003335 -8.236129509282987e-11 7.699338039665683e-10 -934.8247900895336 -1.0761442318355658e-10 7.022541451191407e-10 -652.565078494464 -6.446291882449279e-11 6.53245991819355e-10 -1013.3670701413436 -4.322526058236853e-11 6.47192456242959e-10 -1497.2551871831795 -9.480178834106368e-11 7.798213268219162e-10 -822.5808188516359 +r_1275 UTP transport 8.271806125530275e-29 8.486130029676431e-11 1.0259101701482896e+20 2.000000000011613e-11 2.2183291452822326e-10 1109.164572634676 -5.800200000002092e-12 2.275432114183192e-10 -3923.023540881989 9.1997999999976e-12 1.8089087368243526e-10 1966.247893242054 -2.239999999999997e-11 2.1796270678330663e-10 -973.047798139763 7.362572473427339e-11 3.505911959973513e-10 476.180298751135 -3.1500399999996607e-11 2.2905549214884434e-10 -727.1510588718523 -2.723620199999428e-11 1.1605851023412951e-09 -4261.1855439372175 -2.2801000000055696e-11 2.323551445127161e-10 -1019.0568155438292 +r_1276 UTP/UMP antiport -8.271806125530275e-29 8.486130029676431e-11 -1.0259101701482896e+20 -2.000000000011613e-11 2.2183291452822326e-10 -1109.164572634676 5.800200000002092e-12 2.275432114183192e-10 3923.023540881989 -9.1997999999976e-12 1.8089087368243526e-10 -1966.247893242054 2.239999999999997e-11 2.1796270678330663e-10 973.047798139763 -7.362572473427339e-11 3.505911959973513e-10 -476.180298751135 3.1500399999996607e-11 2.2905549214884434e-10 727.1510588718523 2.723620199999428e-11 1.1605851023412951e-09 4261.1855439372175 2.2801000000055696e-11 2.323551445127161e-10 1019.0568155438292 +r_1277 water diffusion -1.3784180777948436 0.0221450258144026 -1.6065536408104646 -2.3160058594760966 0.0312407256296298 -1.3489052932144503 -4.575055421268234 0.0808232873167659 -1.7666078303891066 -7.028320675836493 0.0369399703802788 -0.525587435235834 -9.819011181787651 0.2472122742917359 -2.517690118840749 -11.076722878063489 0.0837222137530518 -0.7558392014921362 -13.807509350739211 0.2777897150629402 -2.0118741766274315 -17.298856229953508 0.4237760822540358 -2.4497346912465483 -18.3015764868027 0.5313314066272218 -2.903200207973154 +r_1278 zymosterol transport -3.7954141070449823e-06 7.165007569420432e-05 -1887.806538981048 -1.9361641082386588e-06 5.112637981246539e-05 -2640.6015685816733 -4.4403648435662e-06 8.456895780732763e-05 -1904.5497563080328 -4.054921316656165e-06 9.390603765238289e-05 -2315.853510317216 -1.248953163884689e-05 0.0002417881891601 -1935.9267917473087 -1.5347152504324084e-05 0.0002716507737124 -1770.0402314755809 -1.3369810929218598e-05 0.000300631474369 -2248.5843364627085 -3.112164783062131e-05 0.0005875117929017 -1887.7914051958128 -2.5460681968366737e-05 0.0005194468222533 -2040.192100505073 +r_1449 inositol-P-ceramide B' (C24) [Golgi] SLIME rxn -3.7817402800488085e-10 3.178581938816632e-09 -840.5077301542261 -3.9562278712340357e-10 3.109044784392636e-09 -785.8608971941891 -2.31133620700062e-10 2.905277531816993e-09 -1256.9688144102238 -5.885480023912932e-10 3.906336712399328e-09 -663.7244025173359 -7.557012693921154e-10 3.893671042972233e-09 -515.2394472096487 -1.2900621824307235e-10 2.511882772005781e-09 -1947.1020902829 -2.4804151957277905e-10 3.0466294774356446e-09 -1228.273993274629 -1.4263126121463923e-10 2.535462616032227e-09 -1777.6345763476957 -5.900997793866267e-11 2.3949464696726913e-09 -4058.544933133333 +r_1450 inositol-P-ceramide B' (C26) [Golgi] SLIME rxn -3.612541885439759e-10 3.6425486598928117e-09 -1008.3062772431772 -1.0466421702650884e-10 3.170752489198501e-09 -3029.452261029602 -1.8084536647359554e-10 3.568075100476773e-09 -1972.997799198649 -1.067722461010586e-10 3.199195664498238e-09 -2996.2801957638308 -4.46315199189896e-10 3.615156139617725e-09 -810.0006780364131 -2.8720266511038165e-10 3.338339959240006e-09 -1162.3638513093076 -3.7887309958208236e-10 3.452395002816807e-09 -911.2272701928396 -7.745873548140722e-11 2.74991986889965e-09 -3550.173975612765 -1.3359919743034682e-11 2.802823323624221e-09 -20979.342522514024 +r_1451 inositol-P-ceramide C (C24) [Golgi] SLIME rxn -3.1498310393365765e-10 3.0911299237148966e-09 -981.3637255812796 -2.384538488643355e-10 3.100901471270397e-09 -1300.419970589196 -4.2212715322419756e-10 3.5254361246414687e-09 -835.1597611559141 -1.1637000152115187e-10 3.253807330072061e-09 -2796.08772668155 -5.915665594485173e-10 3.847358993983385e-09 -650.3678973284176 -2.596620389238876e-10 2.942790363337737e-09 -1133.315588036467 -5.165989237307395e-10 3.778585079044284e-09 -731.4349499136296 -1.5134944784158128e-10 2.8556568703999e-09 -1886.797019166492 -7.224199938883451e-11 2.72423537665073e-09 -3770.985575839114 +r_1452 inositol-P-ceramide C (C26) [Golgi] SLIME rxn -3.745258204673691e-10 3.7879992251838664e-09 -1011.4120357461172 -1.2687184402519138e-11 3.813860440405201e-09 -30060.7315177663 -1.4843642778418006e-10 3.470825580146729e-09 -2338.257280883338 -2.2738214044318382e-10 3.921915100271426e-09 -1724.8122885233363 -4.5946109306186444e-10 4.177152554074601e-09 -909.141735209376 -3.891841555191609e-10 3.764452423211049e-09 -967.2676469033976 -1.7469646293824407e-10 3.340556159266928e-09 -1912.205950298964 -1.6048656083819135e-10 3.374964591994045e-09 -2102.957764417927 -1.612961787506056e-11 2.869401579469803e-09 -17789.64388180851 +r_1453 inositol-P-ceramide A (C24) [Golgi] SLIME rxn -5.807024491073434e-10 4.044656477698047e-09 -696.5110073008125 -3.0434059353788555e-10 3.812771212769996e-09 -1252.797455787102 -5.045145634413366e-10 4.0941033623406314e-09 -811.493593844825 -4.217955959760226e-10 3.8778556635337365e-09 -919.3684572643514 -4.2995503615806066e-10 4.139879577531307e-09 -962.8633762553252 -4.738526124247368e-10 3.6017375050665396e-09 -760.0965807988687 -6.24156778332662e-10 4.062366022602787e-09 -650.856669930713 -5.315659328816051e-10 3.964894385639613e-09 -745.8894824478356 -5.817221083492356e-10 4.258419569939022e-09 -732.0367420834708 +r_1454 inositol-P-ceramide A (C26) [Golgi] SLIME rxn -5.457079238661553e-10 4.256288740274777e-09 -779.9572910945501 -7.731190993700368e-10 3.82890934963805e-09 -495.2547871030444 -9.578327547674243e-10 4.6556608327723366e-09 -486.0619778974669 -5.921170426443442e-10 3.533699552831273e-09 -596.7907184447981 -7.106195017710734e-10 4.550598549521305e-09 -640.3706256554835 -6.983672282316562e-10 4.4518380161265995e-09 -637.4637634986323 -7.558607251166e-10 4.433590724084201e-09 -586.5618594484149 -5.682335024453644e-10 3.96977200592448e-09 -698.6163238951533 -9.172944264317883e-10 4.605579845924907e-09 -502.083051331762 +r_1455 inositol-P-ceramide B (C24) [Golgi] SLIME rxn -6.632754921653169e-10 4.113433547976141e-09 -620.1696876432901 -3.6418478335890276e-10 3.606565658853028e-09 -990.3120129263532 -5.18248738248042e-10 3.930435393156176e-09 -758.4071321510883 -3.8039324312094064e-10 3.570274804525292e-09 -938.5747168464226 -4.6023242706484554e-10 3.794273556804508e-09 -824.4255149517974 -5.851779043952625e-10 4.323989660456565e-09 -738.918819042746 -5.83494536697839e-10 3.828412524601908e-09 -656.1179726322681 -6.191742661577513e-10 3.955339970077019e-09 -638.8088436913963 -9.291840645468363e-10 4.851987550766886e-09 -522.1772236411742 +r_1456 inositol-P-ceramide B (C26) [Golgi] SLIME rxn -6.190317877226817e-10 4.36674177003308e-09 -705.4147875180399 -6.491870814772713e-10 4.111250491007903e-09 -633.2920984275379 -6.013939849974183e-10 4.0300631867485184e-09 -670.1203017129974 -5.685291911493592e-10 3.6046738317095516e-09 -634.0349603548433 -5.88860678271798e-10 3.9357602217087e-09 -668.3686595035449 -4.263926213153116e-10 4.007428768209056e-09 -939.8447740130138 -7.100882137822665e-10 3.840412060884854e-09 -540.8359111368711 -1.1891314661550608e-09 4.543226745777027e-09 -382.0626125105496 -8.792718902170661e-10 4.55594238892122e-09 -518.1494415562963 +r_1457 inositol-P-ceramide D (C24) [Golgi] SLIME rxn -5.08585586419853e-10 3.866068851006271e-09 -760.1609157312437 -3.9113622337635984e-10 3.885322155620758e-09 -993.3424529392709 -3.05757042637494e-10 3.783768415733821e-09 -1237.5081807093034 -2.5776715349747276e-10 3.475725870991004e-09 -1348.3975067541264 -2.779248009971789e-10 3.674975546231466e-09 -1322.2913295416083 -6.122659133017155e-10 4.157713954096916e-09 -679.0699700520576 -4.96508335184222e-10 4.1753186999832695e-09 -840.9362752055466 -6.511096507909275e-10 3.7045283252451525e-09 -568.9561383009948 -6.83654795857243e-10 3.7824188025076045e-09 -553.2644289819956 +r_1458 inositol-P-ceramide D (C26) [Golgi] SLIME rxn -9.771899002242735e-10 5.428651553965217e-09 -555.5370100242845 -6.945863263468614e-11 4.428778463404269e-09 -6376.138278876271 -5.371356941419112e-10 4.9611235098063455e-09 -923.6257362735636 -1.0931430336652915e-10 4.1929377797211295e-09 -3835.6716830205423 -2.557336441178954e-10 4.643895622659122e-09 -1815.9110971406824 -6.997768481278506e-10 4.79907403943836e-09 -685.8006309122077 -6.601086176847054e-10 5.082432123219647e-09 -769.9387626609082 -1.3385995848864463e-09 5.295791696230257e-09 -395.621794300758 -1.1785853002919794e-09 5.308303543802118e-09 -450.3962116689437 +r_1479 inositol phosphomannosylinositol phosphoceramide A (C24) [Golgi] SLIME rxn -1.6619248116127559e-10 3.3116092436341e-09 -1992.634817468347 -1.5716883335315618e-10 4.002049806058221e-09 -2546.338049774583 -2.6758663202068976e-11 3.397809930256217e-09 -12697.980854265918 -5.877062568738542e-11 3.133586668674142e-09 -5331.892645387879 -4.391571605657897e-11 3.439436280584495e-09 -7831.90299380132 -4.0042379168136296e-10 3.853477838520335e-09 -962.3498699564632 -6.398120105367889e-11 3.2903469421783594e-09 -5142.677674052769 -1.2476863451438219e-10 3.015404666831108e-09 -2416.7970408328224 2.743090791005332e-11 3.014784760111807e-09 10990.46655691225 +r_1480 inositol phosphomannosylinositol phosphoceramide A (C26) [Golgi] SLIME rxn 6.668212366623157e-11 3.271627386167281e-09 4906.303528278394 -4.0410663579986325e-10 3.709629469423154e-09 -917.9828146302392 -2.2718860537772547e-10 3.484385783481547e-09 -1533.6974218792272 -6.41462461359334e-10 3.9794456186699414e-09 -620.370771227521 1.4267832019365051e-11 3.080598471114206e-09 21591.21628943385 1.604443508603346e-10 3.2469339218447995e-09 2023.713458550639 -2.1256274614948336e-10 3.37601561915418e-09 -1588.244262134259 -1.737371022549477e-10 2.786497114364542e-09 -1603.8584034143391 2.3016974730064813e-11 2.7460440244443164e-09 11930.516745354154 +r_1481 inositol phosphomannosylinositol phosphoceramide B' (C24) [Golgi] SLIME rxn 3.21140477803144e-11 2.921552214885352e-09 9097.42750235377 7.137418170455137e-11 3.472936541001969e-09 4865.816263054274 4.797143474939806e-11 3.33953609475553e-09 6961.509723862146 6.757465570123189e-11 3.0766413506980993e-09 4552.951574479146 -8.075698253836022e-11 3.230878884520829e-09 -4000.7424534295046 1.0284829910745419e-10 2.9143496039831276e-09 2833.639087155212 -2.8628579075330982e-11 2.913987509948815e-09 -10178.596367920243 5.731723339527457e-11 2.2894370681621994e-09 3994.3258467722 -5.5300541948676224e-11 2.6534051156390104e-09 -4798.153909778323 +r_1482 inositol phosphomannosylinositol phosphoceramide B' (C26) [Golgi] SLIME rxn 1.7204606800273964e-10 2.7372801711656183e-09 1591.0158267156853 3.9872309209396647e-10 3.190984411049861e-09 800.3008790616636 5.3677590378308624e-11 3.433349177408201e-09 6396.243112275834 2.0719304061183477e-10 3.074385383613173e-09 1483.8265679844292 1.928426867877128e-10 2.980293477321178e-09 1545.45320176024 2.472374835028811e-10 2.966373061902746e-09 1199.807173198387 5.1223247794700247e-11 3.2363027076271273e-09 6318.034968415195 1.3225100475543543e-10 2.439269842340511e-09 1844.4244312936 2.3210804051456067e-10 2.1241581951561115e-09 915.1592467228028 +r_1483 inositol phosphomannosylinositol phosphoceramide B (C24) [Golgi] SLIME rxn -1.7229337072039656e-10 3.649048869167793e-09 -2117.9276102790927 -1.5909248012736366e-10 3.5970317309971273e-09 -2260.969046505199 5.285626921239605e-11 3.231394032655874e-09 6113.54921716275 -5.0157647186986746e-11 3.126592050965915e-09 -6233.530132125296 -7.397967161325667e-11 3.350610353809069e-09 -4529.096008056167 -1.0340079666493951e-11 3.0193620281869714e-09 -29200.56832802679 -5.259619450990558e-11 3.0030541644952702e-09 -5709.641529159864 -2.4615595202183617e-10 3.1671497845576957e-09 -1286.6435926264917 -1.1459766543728663e-11 3.162224693563673e-09 -27594.145844918585 +r_1484 inositol phosphomannosylinositol phosphoceramide B (C26) [Golgi] SLIME rxn 7.437210516816063e-11 3.418271466278573e-09 4596.174141567753 -7.468835614720631e-11 3.83926719329822e-09 -5140.382505850381 -3.8612108036624525e-11 3.985794260180218e-09 -10322.653858731555 -5.849829598332227e-11 3.163363134000365e-09 -5407.615864404379 1.1069881623754476e-10 3.29887436335597e-09 2980.044841922276 3.3125704006077724e-11 3.438580251832848e-09 10380.399013412534 -2.78362657613226e-11 3.1403147983605993e-09 -11281.379568964829 5.586778635492044e-11 2.731053313935057e-09 4888.422277168899 6.492430544153466e-11 2.9207800183959554e-09 4498.746653556676 +r_1485 inositol phosphomannosylinositol phosphoceramide C (C24) [Golgi] SLIME rxn -1.0941768861325044e-10 3.457927750863479e-09 -3160.300491345533 -1.3736617416571795e-10 4.1345590430004336e-09 -3009.881485097284 -7.023902917670144e-11 3.486195980836002e-09 -4963.33167143544 -9.833112957190467e-11 3.384376727616116e-09 -3441.816180034106 -1.2120133662885522e-10 3.3346169634333834e-09 -2751.303786066901 -2.138168215879447e-11 2.8007586351871678e-09 -13098.86946399674 -5.39720538366665e-11 3.325403757311969e-09 -6161.343734250891 1.2128940147828295e-10 2.722410013325767e-09 2244.557216166343 -3.9670786400907125e-11 2.9217625405109e-09 -7365.02299446247 +r_1486 inositol phosphomannosylinositol phosphoceramide C (C26) [Golgi] SLIME rxn -1.5545260607094972e-10 4.24035214429341e-09 -2727.745935862974 6.582489372402969e-11 4.931298389162468e-09 7491.540221602019 1.613614079695975e-11 4.183045279037386e-09 25923.455500744785 -9.327541274124271e-11 4.0720127708212824e-09 -4365.580007796415 5.851074697364963e-11 4.093740650063632e-09 6996.561934010604 9.445119100573304e-11 3.963468794644059e-09 4196.314257597326 5.0076876502775326e-11 3.986536977656971e-09 7960.833933873714 -6.319248582450864e-11 3.407537397055177e-09 -5392.314216785558 6.137528892674403e-11 3.760092852642322e-09 6126.39535942596 +r_1487 inositol phosphomannosylinositol phosphoceramide D (C24) [Golgi] SLIME rxn -2.0955404496637945e-11 4.0153309589617115e-09 -19161.314493384874 -1.0186225721878739e-10 4.048110529074805e-09 -3974.1025180504 -2.789857989494661e-10 4.689743350090274e-09 -1680.997157471713 6.635403847034932e-11 4.380519026334432e-09 6601.736875882681 -1.8650894405126423e-10 4.056029303933598e-09 -2174.710346769616 -1.4855680168717793e-10 3.9370782466025435e-09 -2650.2174265255176 -2.830420101746668e-10 4.399051967635149e-09 -1554.2046090332915 -2.1461722938880056e-10 3.640772833917123e-09 -1696.4028676940466 -4.944700048010463e-10 4.323207234177111e-09 -874.3113216577385 +r_1488 inositol phosphomannosylinositol phosphoceramide D (C26) [Golgi] SLIME rxn 1.3314273321021768e-10 5.125512041277707e-09 3849.637090734114 4.833142535983344e-10 5.275402465644085e-09 1091.5056666274709 4.977286696917772e-10 5.473603741644277e-09 1099.71638664774 6.587481385718346e-10 5.0151779680368695e-09 761.3194898599287 1.0835021099907836e-10 5.6146325765066045e-09 5181.930450097936 -1.1927967575877298e-10 5.436047913005219e-09 -4557.396621364809 6.01974444683507e-10 4.3747603124351095e-09 726.7352212493298 4.604557302720018e-10 4.7974833626214015e-09 1041.8989377735438 2.0960946632713654e-10 4.419668567134543e-09 2108.5252706272267 +r_1509 mannosylinositol phosphorylceramide B' (C24) [Golgi] SLIME rxn 1.829337353529337e-10 2.562410001608277e-09 1400.7312520375888 1.807573538651681e-10 3.000567642087201e-09 1659.9975480529586 2.1290709470621207e-10 2.7453088552157567e-09 1289.439818341411 1.7178597166172848e-10 3.225408568849628e-09 1877.573900621481 1.3150610453290012e-10 2.668621521512414e-09 2029.275774680696 2.0771260821379096e-10 3.213346056595828e-09 1547.0154095260548 2.2588963369461047e-10 2.6606225747646086e-09 1177.8418209140193 2.1707000286363347e-10 2.256299243134941e-09 1039.433921485863 1.682997116774167e-10 2.019075212740536e-09 1199.690238691874 +r_1510 mannosylinositol phosphorylceramide B' (C26) [Golgi] SLIME rxn 9.118860962733648e-11 3.240124057358556e-09 3553.211383088391 2.3066834931125624e-10 3.346389354886198e-09 1450.7362474644024 1.6672885034026627e-10 2.933911119766266e-09 1759.690127880468 1.4524068508214538e-10 3.042687818129244e-09 2094.9280268186267 2.1556778481146286e-10 3.111475795453972e-09 1443.386263942588 2.167487149090404e-10 3.0426553433756958e-09 1403.7708803268154 6.333230382864434e-11 3.1689516238791434e-09 5003.6891638321695 2.6872895234507403e-10 2.933511661391138e-09 1091.624715458357 1.664348635044778e-10 2.7427973869420206e-09 1647.9704607491851 +r_1511 mannosylinositol phosphorylceramide C (C24) [Golgi] SLIME rxn 4.090067991576131e-12 3.2370934777774842e-09 79145.22410005346 1.210873707783329e-10 3.240979605251005e-09 2676.562868958534 9.702079658246127e-11 2.9282693596122197e-09 3018.187298764739 7.065788584838996e-11 3.116109666086436e-09 4410.137139926104 2.632317070620552e-11 3.048684751209553e-09 11581.753525196897 -1.3901761959544108e-10 3.392235803757881e-09 -2440.148100384481 6.277196020966229e-11 2.823630047147517e-09 4498.234622140864 2.008846630218068e-10 2.79914660333541e-09 1393.4098109976433 2.3026875232394624e-10 2.506991896827753e-09 1088.7243151866614 +r_1512 mannosylinositol phosphorylceramide C (C26) [Golgi] SLIME rxn 9.503728902744448e-11 3.489282456497465e-09 3671.487783589707 2.0543930399307606e-10 3.70308583077213e-09 1802.5206271614588 -1.601617684728986e-10 3.832728389081425e-09 -2393.0357573005763 8.767731962215613e-11 3.7239200945775934e-09 4247.301480731577 1.2450426144655408e-10 3.2282052660791434e-09 2592.847207454754 1.0735199041825843e-10 3.438857842822129e-09 3203.34800447002 -4.9121773949230805e-11 3.892748499412273e-09 -7924.690389715109 1.4145989603038903e-10 2.9649827788063703e-09 2095.988235541626 2.1432766864830766e-10 3.145007159315375e-09 1467.3827131839182 +r_1513 mannosylinositol phosphorylceramide A (C24) [Golgi] SLIME rxn 2.6305311134194453e-11 3.130016374756817e-09 11898.800051401358 2.2297631940577639e-10 3.3230402457985902e-09 1490.3108341972677 1.4369244139150671e-11 3.4218795959841072e-09 23813.91507338093 -3.5813871887549936e-11 3.181893560710269e-09 -8884.528237273333 2.163589793641512e-10 3.04485404753406e-09 1407.315775144836 1.4597700109412288e-10 2.8805247001498315e-09 1973.2729666726943 1.3546545813452268e-10 2.79396705352049e-09 2062.494079299512 1.4973886096254606e-10 2.582850636392843e-09 1724.9033549406306 2.397380277728633e-10 2.720281028836914e-09 1134.6889995333609 +r_1514 mannosylinositol phosphorylceramide A (C26) [Golgi] SLIME rxn 2.0381775640993603e-10 3.597178073798403e-09 1764.8992595931852 -5.788862110967761e-10 3.839124345817625e-09 -663.1915344025726 -3.594997097246993e-11 3.581231869147472e-09 -9961.710043910569 -3.3434021083258004e-10 3.762986933189794e-09 -1125.4963690485015 -1.1096485840891384e-10 3.409564068198824e-09 -3072.6521144507965 1.3654099643979488e-10 3.364652010984254e-09 2464.206427897157 -6.689749529365862e-11 3.507289013446605e-09 -5242.78076189658 7.820181247840912e-11 3.0507738051833207e-09 3901.154856258113 -2.8122946577766756e-10 3.537169224854346e-09 -1257.7519980252484 +r_1515 mannosylinositol phosphorylceramide B (C24) [Golgi] SLIME rxn 2.1816210239332883e-11 2.9934335915958842e-09 13721.143859344384 -1.6317355891061735e-11 3.5311265075242877e-09 -21640.310667358524 2.959778237719998e-10 3.1283197706896422e-09 1056.9439733091208 1.2495772525952492e-10 3.15126073309197e-09 2521.861474788462 1.63914255883689e-10 2.955769384088424e-09 1803.2411934845927 1.4715108993076268e-10 3.249865087341105e-09 2208.5226068459474 9.64235960636478e-11 3.408869217701528e-09 3535.306042155267 1.2463922894628923e-10 2.633579766843649e-09 2112.9621782067807 2.307302282843364e-10 3.295633962141171e-09 1428.3494566996455 +r_1516 mannosylinositol phosphorylceramide B (C26) [Golgi] SLIME rxn 3.038920814314395e-11 3.1399186353328793e-09 10332.34765625596 -6.887275235677643e-11 4.649069524910765e-09 -6750.23048422333 9.000687019241044e-11 3.691607040386029e-09 4101.472512591947 -2.5705639125393905e-10 3.6592881713670868e-09 -1423.535183667997 1.812830984128192e-10 3.2213854363982804e-09 1776.9916029692506 1.6499929144822235e-10 3.414462873936634e-09 2069.380325192554 -6.9359279498414e-11 3.28998111826076e-09 -4743.389986246887 9.762111472831404e-11 3.147357012691411e-09 3224.0535476886457 -5.0471739534394306e-11 3.3296420653639277e-09 -6597.042416370296 +r_1517 mannosylinositol phosphorylceramide D (C24) [Golgi] SLIME rxn 7.762712170185472e-11 4.163300330379684e-09 5363.203271106485 -2.0060616637517008e-10 4.036121032252529e-09 -2011.9625957580224 -4.444145119502423e-11 3.765849544271172e-09 -8473.732164472623 -9.766126552708078e-11 4.313725465180076e-09 -4417.028022214099 -3.815872871006619e-11 4.009092360004998e-09 -10506.357249127665 -1.8146699590301307e-10 4.090663012520924e-09 -2254.2187311610214 -5.993614774772611e-11 4.312181613991807e-09 -7194.625907794358 -8.533259090307187e-10 4.434099110893653e-09 -519.625510484064 -6.496382731063857e-10 4.586616584879304e-09 -706.026226402488 +r_1518 mannosylinositol phosphorylceramide D (C26) [Golgi] SLIME rxn -7.717245809080063e-10 5.991058610978801e-09 -776.3208221163252 -5.5426619090405286e-11 5.2934167005010335e-09 -9550.31497026193 -5.078566303580089e-10 6.027014695709206e-09 -1186.755146124708 2.104019509737541e-10 5.717779079114657e-09 2717.550408944593 -8.07561427948128e-10 6.055856736167391e-09 -749.8942528191644 -7.656077480169915e-10 6.174982103719539e-09 -806.5464488458254 -2.5475307009490455e-10 6.347388857260243e-09 -2491.5848334607363 -4.055799554282822e-10 6.3340910203822075e-09 -1561.7367021241391 -1.6874779147118455e-10 6.826677098067184e-09 -4045.491226018749 +r_1542 (1->3)-beta-D-glucan exchange -9.20999999999986e-10 2.6976574043220496e-10 -29.29052556267199 -8.229999999943633e-10 3.8170687710075855e-10 -46.37993646456534 -8.592000000165552e-10 3.4842451109621765e-10 -40.552201011348245 -7.37000000000039e-10 4.4076054039670865e-10 -59.80468662098851 -1.1100000000000043e-10 3.1606799869009783e-10 -284.7459447658528 -9.185999999999867e-10 2.7347577186937803e-10 -29.770930967709774 -9.201999999999859e-10 2.710104229173804e-10 -29.45125221879857 -7.108000000000371e-10 4.538772531336729e-10 -63.85442503287132 -7.728000000000374e-10 4.1906477191073774e-10 -54.22680795946137 +r_1543 (1->3)-beta-D-glucan transport -2.2661278590239183e-10 1.200655414921281e-09 -529.8268630960811 -9.129728077734183e-11 6.95033059347319e-10 -761.2856083220962 -1.6785945800934948e-10 4.168873645909243e-10 -248.35500455845883 -2.7311534001079704e-10 3.6578047194652656e-10 -133.92893710476542 -1.9448342367812675e-10 4.030162591509744e-10 -207.2239636309432 -3.0688047223236376e-10 4.6523217553349575e-10 -151.6004495656639 -2.9147843239119257e-10 3.946157018488313e-10 -135.384185585031 -4.295947900657125e-10 4.369558683542419e-10 -101.71349337998332 -4.5907448719574966e-10 4.951889773512796e-10 -107.86680400737036 +r_1545 (R)-carnitine exchange 8.406000000000137e-10 4.3775560075592246e-10 52.07656444871702 7.502000000000401e-10 5.605914845611861e-10 74.7256044469683 1.6119999999999888e-10 9.014305715999971e-10 559.200106451615 4.750000000000191e-10 6.078230744040355e-10 127.96275250610758 2.009999999999988e-10 8.80428322355781e-10 438.02404097302815 8.025999999997112e-10 4.543946906689431e-10 56.615336490045664 2.6320000000000344e-10 8.63293006436974e-10 327.99886262802534 1.6719999999999868e-10 8.476956279087276e-10 506.9949927683818 3.026000000000064e-10 7.982234474972707e-10 263.7883170843536 +r_1546 (R)-lactate exchange -5.092000000000219e-10 5.027583049365226e-10 -98.73493812578576 -1.4519999999999938e-10 3.5572780106942086e-10 -244.99159853266005 -9.340000000000087e-11 2.9102126842506664e-10 -311.5859404979271 -9.400000000000088e-11 2.9526502719973714e-10 -314.1117310635472 -3.7000000000001134e-10 4.882086332029631e-10 -131.94827924404 -5.3565516247841586e-11 9.156311170177043e-10 -1709.366736579524 -5.200000000000225e-10 5.060150296602231e-10 -97.31058262696178 -6.238000000000306e-10 4.910415301752892e-10 -78.7177829713474 -3.1540000000000736e-10 4.736746916848166e-10 -150.18221042638095 +r_1547 (R)-mevalonate exchange 8.408384159608025e-05 0.0012417800680464 1476.8355542217594 2.654731889812178e-05 0.0006620462425139 2493.834669537069 7.513428593034897e-05 0.0014193039289597 1889.022982497573 4.9698178447620224e-05 0.0014344820845452 2886.387649110949 0.0002422569149972 0.0040840400097718 1685.8301071891508 0.000182057134202 0.0034352208484097 1886.8916417175988 0.0004783329664688 0.0074234216939975 1551.9360391984058 0.000541335748923 0.0085135974472776 1572.701870182192 0.0006907548106326 0.0105166482990057 1522.4864361600476 +r_1548 (R)-pantothenate exchange -2.179957468979079e-11 2.0428478928998567e-10 -937.104471976954 -3.3599961994268494e-11 2.3169312223351827e-10 -689.5636437715036 -1.560158736355538e-11 1.9226001631963608e-10 -1232.3106094239297 -4.2192520429136596e-11 2.6537833897625265e-10 -628.9701024662943 -4.248054294496385e-11 4.6485441458691647e-10 -1094.2760670200566 -3.4188803050670106e-11 2.502443505894197e-10 -731.9482645196463 -3.158149952450344e-11 2.8394422306401687e-10 -899.0840439470278 -4.4673793373757706e-11 6.994758913863339e-10 -1565.7409827149806 -3.5801625362236933e-11 2.8519777086103406e-10 -796.6056512111787 +r_1549 (R,R)-2,3-butanediol exchange 0.0015070825174226 0.0062839093278426 416.9585444192699 6.305953347999993e-05 0.0011576634324264 1835.826192392608 0.0001913371173377 0.0034233427901481 1789.1681644311896 0.0001223367881366 0.0025356126323256 2072.6493403551744 0.0005083854191213 0.0096208375828497 1892.4298811474628 0.0011805449827427 0.0121992120048953 1033.3542713936592 0.0007819630571066 0.01382761712777 1768.321022598487 0.0017768140642608 0.022494416390013 1265.997204911319 0.000999675184675 0.0203790433044207 2038.5664880784127 +r_1550 (S)-3-methyl-2-oxopentanoate exchange 7.55042161097821e-05 0.0013554675204791 1795.220969526099 2.968753799168636e-05 0.000699211704638 2355.236412106099 0.0001095162962624 0.0019968435864202 1823.3300929337 0.0001167922933365 0.0022057570008332 1888.6151969609543 0.0003008103098912 0.0056787266425033 1887.8098442026983 0.0004180281415605 0.0067691132290985 1619.2960607458492 0.0004876503923823 0.008890777279494 1823.186737543405 0.000445962333163 0.0104301507792779 2338.796351992394 0.0004265806054543 0.0100465766835891 2355.141456299314 +r_1551 (S)-lactate exchange -4.442000000000169e-10 5.053092394618454e-10 -113.75714530883074 -2.1259999999999963e-10 4.13080339732392e-10 -194.29931313847257 -6.474000000000321e-10 4.819955434864401e-10 -74.45096439394752 -1.8019999999999828e-10 3.8956169172844603e-10 -216.18295878382327 -1.7750000212335258e-10 3.954427909186391e-10 -222.78466827500569 -5.748000000000267e-10 5.000549679727262e-10 -86.99634098342082 -5.51800000000025e-10 5.049433171661085e-10 -91.50839383220108 -6.418000000000316e-10 4.853244976029879e-10 -75.61927354362166 -4.822000000000199e-10 5.116009256260464e-10 -106.09724712277593 +r_1552 (S)-malate exchange 3.030730287100511e-05 0.0008745003688689 2885.4443847776283 1.3889266562776164e-05 0.0007863843728414 5661.813525481272 2.3087830357720287e-05 0.0016325415800503 7071.004744733164 0.0001101743461417 0.0044969472181815 4081.6645395799446 0.0014505823243809 0.0195743396658025 1349.4125315607853 5.643079458921869e-05 0.002303319066073 4081.6704475628326 0.0010024392362054 0.0178900844181813 1784.6552461275196 0.0004846147311274 0.0143010791437978 2951.0203106140616 0.0010638761387344 0.0308381817817043 2898.6627915529352 +r_1553 1-(sn-glycero-3-phospho)-1D-myo-inositol exchange 4.381675829799332e-05 0.0005637492362709 1286.6064450432268 4.281792997193235e-05 0.00059784023124 1396.2380517507138 8.438422920466577e-05 0.0010103394498496 1197.3083825879346 0.000110437387846 0.0014004420594812 1268.086910416136 0.0002181280113576 0.0028109958712826 1288.690917680146 0.0001936415818588 0.0023207444977355 1198.4742509629243 0.0004072184039213 0.0046852959901513 1150.560963118019 0.0005387302455927 0.0067317678412796 1249.5618904546036 0.0005209376560945 0.0064927745101359 1246.363059797276 +r_1554 1-acylglycerophosphocholine exchange 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1560 1D-myo-inositol 1,3,4,5,6-pentakisphosphate diffusion 8.858555683995367e-05 0.0018062654419247 2039.006703076984 0.000161258525556 0.0032880436614507 2038.9890395638715 0.0001362405055568 0.0027779454740311 2039.001149237799 0.000169591664418 0.0037466267740488 2209.2045543077115 0.0002675961004506 0.0066852571599559 2498.2640437200243 0.000300950600553 0.0064098734137924 2129.875601515358 0.00060284555637 0.0122921233348519 2039.0169928211023 0.0006875186008978 0.0161920053129264 2355.1370525511943 0.0005857574819385 0.0146339719924769 2498.29877444284 +r_1562 1D-myo-inositol 1-phosphate transport 0.0013098596434384 0.0058147900589461 443.9246668965265 0.0024683081405298 0.0107591840409093 435.8930663575877 0.0020259994315047 0.0089770990300637 443.0948444736815 0.0030277019252221 0.0133191286322237 439.90884707868 0.0064912792580408 0.0275739880747311 424.78511520783286 0.0052762975739607 0.0224761739599027 425.9838199957825 0.0096798715205894 0.0413180882677869 426.845420209369 0.0144910207705571 0.0622002364582701 429.2329535863248 0.0140096677304236 0.0600157547177159 428.38813790982863 +r_1563 2'-deoxyadenosine exchange -9.827999999999644e-10 1.3155843387752042e-10 -13.386084033122222 -9.747999999999671e-10 1.5674780373196202e-10 -16.079996279438582 -9.845999999999635e-10 1.2314979973444173e-10 -12.507596966732304 -9.805999999999652e-10 1.3794000684753963e-10 -14.066898515964157 -9.799999999999654e-10 1.4143550049460902e-10 -14.432193928021842 -9.80999999999965e-10 1.3653837755631535e-10 -13.918285173936823 -9.175999999999871e-10 2.7500066376833117e-10 -29.969557952085346 -9.721999999999682e-10 1.6562803666439628e-10 -17.036416032133484 -9.82999999999964e-10 1.2928396214757015e-10 -13.15197987259154 +r_1564 2'-deoxyguanosine exchange -1.3609033257663262e-10 3.527356589957199e-10 -259.19229699662463 -1.1840000000000018e-10 3.261942987608861e-10 -275.5019415210182 -1.94198317655269e-10 7.684054766605895e-10 -395.68081018323966 -5.819088602385657e-11 3.135109013346032e-10 -538.7628935673414 -1.4639999999999936e-10 3.5635998440859407e-10 -243.41528989658173 -1.4099999999999951e-10 3.5205651358516883e-10 -249.6854706277802 -1.8139999999999828e-10 3.9054390906655767e-10 -215.29432693856748 -2.2580000000000055e-10 4.22906762804749e-10 -187.292631888728 -1.7979999999999828e-10 3.88203684191809e-10 -215.9086118975599 +r_1565 2'-deoxyinosine exchange 9.505999999999756e-10 2.3102015942945523e-10 24.302562532028315 8.34200000000016e-10 3.8566839126585536e-10 46.23212554133876 9.34599999999981e-10 2.667153302933255e-10 28.53791250731124 9.43599999999978e-10 2.3922894076015225e-10 25.352791517608924 9.615999999999715e-10 1.9832626316584622e-10 20.62461139411939 9.445999999999775e-10 2.398798625764344e-10 25.394861589714168 8.384000000000145e-10 3.968840427488816e-10 47.3382684576425 8.006000000000275e-10 4.148180984611757e-10 51.813402255953214 9.45799999999977e-10 2.3931948262301616e-10 25.30339211493149 +r_1566 2'-deoxyuridine exchange -1.6500427027420807e-11 6.492443896220867e-10 -3934.7126504250873 -4.30602241850506e-10 7.034836390738195e-10 -163.3720335617879 1.2454966873886788e-10 6.099390169836936e-10 489.71548713027727 -3.899634565115882e-10 6.562483650811109e-10 -168.28458003515763 2.1734842171259027e-12 6.797265443288296e-10 31273.59007132166 4.095691966525945e-11 5.207891318199391e-10 1271.5534666091692 -2.6467131001687143e-11 6.650219535342434e-10 -2512.6333242989263 -7.807712124316017e-12 5.751507435600266e-10 -7366.444028703374 -6.401793811997416e-11 6.260945800408192e-10 -977.9986647921608 +r_1567 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport -0.0052036040195815 0.0018701166319442 -35.93887284479828 -0.0085591365412619 0.0016032650909514 -18.73162185487317 -0.0234086327463921 0.0029191679314326 -12.47047601224208 -0.0390438620665965 0.003828058293807 -9.80450726743578 -0.0427175648851997 0.0072635454484343 -17.00365053100416 -0.0591844219041012 0.0072112578109409 -12.18438497654951 -0.0690375188209769 0.0111956780611244 -16.21680247541383 -0.0871159029810305 0.0171509635680712 -19.68752315154885 -0.0918926165263695 0.0156337565318725 -17.013071477169554 +r_1568 2-dehydropantoate transport -4.3147969881399005e-06 3.1292272186927546e-08 -0.7252316220888431 -7.030547087741129e-06 4.349889074552399e-08 -0.6187127431572313 -1.6327724306128466e-05 4.5985109812123784e-08 -0.2816382059737723 -2.4272181125290883e-05 6.595842952393623e-08 -0.2717449626115781 -3.422433658109372e-05 1.4398309804550876e-07 -0.4207038395159081 -4.0564295146042406e-05 1.18484975630018e-07 -0.2920917895983158 -4.541351676309623e-05 2.145610322200925e-07 -0.4724607286843029 -5.333376783807367e-05 3.1296325095730425e-07 -0.5868013148958275 -6.047408065625624e-05 3.043717571062926e-07 -0.5033094406782096 +r_1572 2-isopropylmalate exchange 4.692544578835434e-05 0.0009842422333548 2097.45952716997 1.6854406035997917e-05 0.0005343054021231 3170.122999184492 0.0001551024446512 0.0025244573539968 1627.606424691516 0.0001069061697726 0.0021082371604368 1972.0444244902048 0.000233123257715 0.0053785418128258 2307.166545948266 0.0003329279007579 0.0052795466920916 1585.792803809108 0.0003820277800289 0.0085349603046727 2234.1203312560256 0.0006819538223967 0.0139354341068723 2043.4571446342748 0.0005016446169887 0.0118144905637614 2355.151468519794 +r_1573 2-isopropylmalate transport 4.692544578835434e-05 0.0009842422333548 2097.45952716997 1.6854406035997917e-05 0.0005343054021231 3170.122999184492 0.0001551024446512 0.0025244573539968 1627.606424691516 0.0001069061697726 0.0021082371604368 1972.0444244902048 0.000233123257715 0.0053785418128258 2307.166545948266 0.0003329279007579 0.0052795466920916 1585.792803809108 0.0003820277800289 0.0085349603046727 2234.1203312560256 0.0006819538223967 0.0139354341068723 2043.4571446342748 0.0005016446169887 0.0118144905637614 2355.151468519794 +r_1574 2-isopropylmalate transport -0.0055438237767022 0.0030042672217435 -54.191246741443344 -0.009035421986526 0.0012763961399187 -14.126580272866162 -0.0250563962037132 0.0038223441649336 -15.254963777940384 -0.0419038317913852 0.0044666764507553 -10.6593508512357 -0.0456172951515272 0.0092721682679002 -20.325993106563608 -0.0634764533835312 0.0098885084879098 -15.578230919995583 -0.0738959932175145 0.0142085440963519 -19.22775982525704 -0.0931034697267721 0.0209024458216121 -22.450769969104144 -0.0982908174937584 0.0191169548041249 -19.44938020821616 +r_1575 2-methyl-1-butanol transport 0.0001277812026342 0.001678062660602 1313.231231205038 2.936618966132437e-05 0.0005991562885071 2040.2929199093944 6.521226654051573e-05 0.0012778081512823 1959.4598057537053 9.869565510511285e-05 0.0017467607021541 1769.845592791121 0.0001641611859607 0.0034303558332604 2089.626614953874 0.0001980532914257 0.0032599265406302 1645.984531315787 0.0002074937417488 0.0046978210658253 2264.078437369152 0.000506793549982 0.009242425520858 1823.706225382205 0.0005567533738393 0.0094710181744607 1701.1155422640684 +r_1576 2-methyl-1-butanol transport -1.7105954506717697e-05 0.0006981997678232 -4081.618289988178 -1.417158934886823e-05 0.0004100214547386 -2893.263731011131 -4.056671111780028e-05 0.00101345887099 -2498.2524909329463 -5.690693913398834e-05 0.0013402386195045 -2355.1409369407943 -4.7121719309965e-05 0.0018077239174542 -3836.285992799037 -1.3907428218745937e-05 0.0007204791116281 -5180.534461842506 -6.650158293808138e-05 0.0027149520188143 -4082.5374357512105 -0.0002047514548417 0.0059077112424437 -2885.308554710331 -0.0002623238453939 0.0065535040106596 -2498.249444619547 +r_1577 2-methylbutanal exchange 6.669890178652947e-05 0.0012665283528643 1898.874372651464 1.689744335392783e-05 0.0004875255565183 2885.2030825419733 5.071218699078062e-05 0.0012021684036319 2370.5710105747653 4.943599157690754e-05 0.0013212611178882 2672.6704082242068 0.000138039847444 0.0034490317411382 2498.5769000774585 0.0001609026757502 0.0037894826437866 2355.1396060489565 0.000208789172845 0.0052160614808397 2498.2432804168243 0.0002991873989374 0.0075511392136011 2523.8827706045467 0.0003037202763316 0.0075878101841506 2498.2889768820937 +r_1578 2-methylbutanal transport 6.669890178652947e-05 0.0012665283528643 1898.874372651464 1.689744335392783e-05 0.0004875255565183 2885.2030825419733 5.071218699078062e-05 0.0012021684036319 2370.5710105747653 4.943599157690754e-05 0.0013212611178882 2672.6704082242068 0.000138039847444 0.0034490317411382 2498.5769000774585 0.0001609026757502 0.0037894826437866 2355.1396060489565 0.000208789172845 0.0052160614808397 2498.2432804168243 0.0002991873989374 0.0075511392136011 2523.8827706045467 0.0003037202763316 0.0075878101841506 2498.2889768820937 +r_1579 2-methylbutanal transport 1.7105954506717697e-05 0.0006981997678232 4081.618289988178 1.417158934886823e-05 0.0004100214547386 2893.263731011131 4.056671111780028e-05 0.00101345887099 2498.2524909329463 5.690693913398834e-05 0.0013402386195045 2355.1409369407943 4.712171930996499e-05 0.0018077239174542 3836.285992799038 1.3907428218745937e-05 0.0007204791116281 5180.534461842506 6.650158293808138e-05 0.0027149520188143 4082.5374357512105 0.0002047514548417 0.0059077112424437 2885.308554710331 0.0002623238453939 0.0065535040106596 2498.249444619547 +r_1580 2-methylbutanol exchange 0.0001277812026342 0.001678062660602 1313.231231205038 2.936618966132437e-05 0.0005991562885071 2040.2929199093944 6.521226654051573e-05 0.0012778081512823 1959.4598057537053 9.869565510511285e-05 0.0017467607021541 1769.845592791121 0.0001641611859607 0.0034303558332604 2089.626614953874 0.0001980532914257 0.0032599265406302 1645.984531315787 0.0002074937417488 0.0046978210658253 2264.078437369152 0.000506793549982 0.009242425520858 1823.706225382205 0.0005567533738393 0.0094710181744607 1701.1155422640684 +r_1581 2-methylbutyl acetate exchange 3.1487820865762914e-05 0.0008447314832724 2682.724494888517 1.0333232992849792e-05 0.0003266328302939 3160.993568227872 2.9281539198500488e-05 0.0007821123460562 2671.0083126240866 2.611274292325729e-05 0.000825457489615 3161.129001426418 4.934912123993792e-05 0.0017442311907748 3534.472645002789 0.0001014208307995 0.0025337801465102 2498.2837613678444 0.0001297263399937 0.0034650053329373 2671.0114022374305 0.0001407287234184 0.0044484520674196 3161.0121653640304 0.0001504662905913 0.0044073109023128 2929.101850647225 +r_1582 2-methylpropanal transport 0.000289551849178 0.0037383278207248 1291.0737166199808 5.6897197581841344e-05 0.0010391901531869 1826.4346880919384 0.0002141584293282 0.0030305113433658 1415.079178938572 0.0002039828832232 0.0030765376340333 1508.2332328181674 0.0004025555437255 0.007350493420014 1825.957568982136 0.0005774789569348 0.0084871830781564 1469.6956445313413 0.0006285748652884 0.0111190771525681 1768.934420797385 0.0011918460802943 0.018890964258679 1585.017106740271 0.0010638209029215 0.0177226422859973 1665.9422875904877 +r_1583 2-methylpropanal transport 3.793154013768106e-05 0.0012242994000625 3227.655390787289 2.3187514060440483e-05 0.0006193436251041 2671.022100470984 5.493920905301429e-05 0.0014068497851739 2560.739059450904 4.964069493098872e-05 0.0014335391890013 2887.8306216186406 4.514391578995459e-05 0.0021861985810782 4842.731390981235 0.0001444784471434 0.0039354931525847 2723.930960219901 0.000109639758281 0.0040957631976393 3735.655077913124 0.0001295473135519 0.0054230937172707 4186.187709016362 0.000192645577228 0.0068090063605889 3534.4732324314364 +r_1585 2-oxobutanoate transporter 0.0041877201944288 0.003194141391251 76.2739926010426 0.00665875448764 0.0014734860963376 22.128554207437865 0.0184120931567865 0.0031838390888317 17.292108299257563 0.0307504402274565 0.0042928198433546 13.960189875661182 0.0335387505030726 0.0084275845219135 25.127902487426933 0.0468735715377625 0.009562855254334 20.40137958471957 0.0542236609436694 0.0134883529915305 24.87540080619598 0.068421732010697 0.0185912026844874 27.17148797341309 0.0724264200707709 0.0180507373340906 24.92286283990354 +r_1586 2-oxoglutarate exchange 2.082031899322726e-05 0.000658171112591 3161.196102735508 4.8682412268931246e-05 0.0014047135314523 2885.4641049676766 9.04467711327545e-05 0.0027713973808115 3064.1197536435907 8.865240192425343e-05 0.003141932227971 3544.102765151959 0.0005485094657928 0.0123309683163218 2248.0866940916903 7.905467391934773e-05 0.0024418835896827 3088.854167147608 0.0003958749900084 0.0114615416895552 2895.2426848965333 0.0003461592747699 0.0111178159671518 3211.7631326041283 0.0013373016266161 0.0282761587606361 2114.4189312163176 +r_1587 2-oxoglutarate transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1588 2-oxoglutarate transport -4.1637255490035074e-06 0.000294460835033 -7072.051977670632 -4.076021266839575e-05 0.0012884198627385 -3160.974338432672 -7.154987371916805e-05 0.0024285957597428 -3394.2698058071223 -6.554599512023927e-05 0.0026842414642909 -4095.202856203424 -0.0005493413195966 0.0123505524259367 -2248.2474893762187 -6.36208296061522e-05 0.0021848809139518 -3434.222608346076 -2.2760000000000074e-10 7.171478928505985e-10 -315.0913413227576 7.180000000000039e-11 6.308124482514387e-10 878.5688694309683 -0.0012088714836371 0.0267839492127234 -2215.6159339732635 +r_1589 2-phenylethanol exchange 0.0001119855506925 0.0012872161003309 1149.4483818403844 1.1319006645108152e-05 0.0003266006981699 2885.418379987503 4.4231192788092894e-05 0.0008665703878255 1959.1838546548604 3.7819732859199424e-05 0.0009450038057723 2498.7056605886646 0.0001199272830272 0.0024455154723445 2039.1652429817464 0.0001264476154497 0.0022741067857755 1798.4576282331589 0.0001355245341033 0.0031920724001595 2355.346521777893 0.0002952725696283 0.0057842794825988 1958.9626933104728 0.000109080619684 0.003448577457598 3161.4941935496245 +r_1590 2-phenylethanol transport -0.0001119855506925 0.0012872161003309 -1149.4483818403844 -1.1319006645108152e-05 0.0003266006981699 -2885.418379987503 -4.4231192788092894e-05 0.0008665703878255 -1959.1838546548609 -3.7819732859199424e-05 0.0009450038057723 -2498.7056605886646 -0.0001199272830272 0.0024455154723445 -2039.1652429817464 -0.0001264476154497 0.0022741067857755 -1798.4576282331589 -0.0001355245341033 0.0031920724001595 -2355.346521777893 -0.0002952725696283 0.0057842794825988 -1958.9626933104728 -0.000109080619684 0.003448577457598 -3161.4941935496245 +r_1591 2-phenylethanol transport 2.026820198746517e-05 0.0005427500115088 2677.839957606876 1.89355404315836e-06 0.0001338969502703 7071.197717020623 1.372180151670588e-05 0.0004849945798535 3534.481819046317 9.584328672517323e-06 0.0004791732627242 4999.54956780945 6.008283080013696e-05 0.0017336031956606 2885.355387843438 2.0837003386372587e-05 0.0010417131932245 4999.342630552214 6.0417557335762815e-05 0.0021354631604139 3534.5076076915225 9.119857637319492e-05 0.0032234021437558 3534.4873483171027 -3.423630176494415e-11 5.498808923848804e-10 -1606.134027443129 +r_1595 3-carboxy-4-methyl-2-oxopentanoate transport -4.1519991679154965e-10 5.219808096851392e-10 -125.71794660238302 2.9525646586410207e-10 7.032172756439066e-10 238.17167681183884 8.921713395052579e-11 4.970152622204577e-10 557.0849905311585 3.750669409110652e-10 7.348377873425007e-10 195.92176947334409 3.2843796181029683e-10 7.725812808138573e-10 235.22898405394872 -1.889394736239602e-10 4.38772061454e-10 -232.2289001012425 1.2936620369378988e-10 5.927681951174757e-10 458.2094690824811 4.6139503613430206e-10 1.0489961397837218e-09 227.3531480903019 3.238405206120286e-10 6.82195705012216e-10 210.65792005365148 +r_1596 3-methyl-2-oxopentanoate transport -0.0023222070853396 0.0183827027838909 -791.604801309201 -0.0021642890027458 0.040239082983912 -1859.22873206214 -0.0150559103172031 0.0305432123883544 -202.8652651673629 -0.0261370927708023 0.0459175683224406 -175.6797082410593 -0.024158602352727 0.0906195052617489 -375.1024332395604 -0.036615321513809 0.0848400875669498 -231.7065208206719 -0.0384460052718256 0.1455239751047049 -378.51520353234 -0.0472229085703282 0.1997419907866762 -422.97689158473577 -0.0499532128315465 0.1997277226790438 -399.8295832393616 +r_1597 3-methyl-oxopentanoate trasport -7.55042161097821e-05 0.0013554675204791 -1795.220969526099 -2.968753799168636e-05 0.000699211704638 -2355.236412106099 -0.0001095162962624 0.0019968435864202 -1823.3300929337 -0.0001167922933365 0.0022057570008332 -1888.6151969609543 -0.0003008103098912 0.0056787266425033 -1887.8098442026983 -0.0004180281415605 0.0067691132290985 -1619.2960607458492 -0.0004876503923823 0.008890777279494 -1823.186737543405 -0.000445962333163 0.0104301507792779 -2338.796351992395 -0.0004265806054543 0.0100465766835891 -2355.141456299314 +r_1598 3-methylbutanal exchange 0.0001110544314437 0.0018717969244178 1685.4770224683502 2.252323854108738e-05 0.0005641635755617 2504.8066446245707 8.52173059779855e-05 0.0016248187572824 1906.6769814363429 9.816607540020806e-05 0.001864173749439 1898.9999771704288 0.0002591742293991 0.0049011254678826 1891.0543225095423 0.0002745113114742 0.0047378561669844 1725.9238395461164 0.0003125849899556 0.0066579352223715 2129.9599905026967 0.0004740777471596 0.0100990862533773 2130.2595015022857 0.0004746030595885 0.0097208714945749 2048.210878160513 +r_1599 3-methylbutanal transport 0.0001110544314437 0.0018717969244178 1685.4770224683502 2.252323854108738e-05 0.0005641635755617 2504.8066446245707 8.52173059779855e-05 0.0016248187572824 1906.6769814363424 9.816607540020806e-05 0.001864173749439 1898.9999771704288 0.0002591742293991 0.0049011254678826 1891.0543225095423 0.0002745113114742 0.0047378561669844 1725.9238395461164 0.0003125849899556 0.0066579352223715 2129.9599905026967 0.0004740777471596 0.0100990862533773 2130.2595015022857 0.0004746030595885 0.0097208714945749 2048.210878160513 +r_1600 3-methylbutanal transport 5.247841301084752e-05 0.0012131569100951 2311.725603905658 1.796080373536082e-05 0.0004797354206987 2671.013100345149 2.7376846541264165e-05 0.0008653885547307 3161.0235073142703 4.604295817903487e-05 0.0012204309432414 2650.6353881432515 0.0001454947566655 0.0034266002401439 2355.136582702792 0.0001370794271951 0.003332456012611 2431.04022302916 0.0001939714839014 0.0048459707723054 2498.2903026958857 0.0002209870716657 0.0063761856843064 2885.3206824477115 0.0002125744326901 0.0061334265023139 2885.30771301905 +r_1601 3-octaprenyl-4-hydroxybenzoate transport 4.1733333333333107e-11 1.878499630898041e-10 450.1197198637502 7.513204228042823e-11 4.130214031910956e-10 549.7273741734649 3.5466666666666553e-11 1.7861705383724655e-10 503.619512699005 5.359999999441368e-11 2.333908044112512e-10 435.43060529025325 3.1666666666666596e-11 1.9721533887882944e-10 622.785280669989 4.553333333333293e-11 1.6785945120567195e-10 368.65179620572496 6.646666667769803e-11 2.1294789772405887e-10 320.38299551963337 1.4293333333333222e-10 3.3332175748387165e-10 233.20085644860603 2.127333333388507e-10 1.845601595465033e-10 86.75657765984799 +r_1603 4-amino-5-hydroxymethyl-2-methylpyrimidine synthetase 1.4304285698678593e-08 2.7227685469348334e-08 190.3463482406786 1.023230302961348e-09 9.736035652120098e-09 951.4999334893496 1.0036052456087168e-07 1.2232574300780582e-08 12.188631291341204 1.530198784796393e-07 1.4801454817945107e-09 0.9672896727541566 2.1538630277957009e-07 1.583571057830673e-09 0.7352236597195907 2.586163225270374e-07 2.3278857879856675e-09 0.9001310378397696 2.8646703795615254e-07 2.6213949996188564e-09 0.9150773570047162 3.374858471848604e-07 4.38503164380362e-09 1.2993231213638676 3.817114677746083e-07 3.2289902873685034e-09 0.845924359096056 +r_1604 4-aminobenzoate exchange 1.0825227850078408e-05 0.0003131294492192 2892.589916404943 1.1769309191224726e-05 0.0003726720984129 3166.473854648815 2.0434120245152395e-05 0.0005896800237692 2885.761739163245 3.403072969485631e-05 0.0009092196379521 2671.7606295981373 7.426749129893189e-05 0.0018772911372926 2527.742763972455 6.323768888555237e-05 0.0014893339855553 2355.13664683525 0.0001340018310225 0.0031564674176614 2355.5405128226103 0.000181089561506 0.0045241223508482 2498.278925203384 0.0002180177178535 0.0048707172809282 2234.0924072048383 +r_1605 4-aminobenzoate transport 1.0825227850078408e-05 0.0003131294492192 2892.589916404943 1.1769309191224726e-05 0.0003726720984129 3166.473854648815 2.0434120245152395e-05 0.0005896800237692 2885.761739163245 3.403072969485631e-05 0.0009092196379521 2671.7606295981373 7.426749129893189e-05 0.0018772911372926 2527.742763972455 6.323768888555237e-05 0.0014893339855553 2355.13664683525 0.0001340018310225 0.0031564674176614 2355.5405128226103 0.000181089561506 0.0045241223508482 2498.278925203384 0.0002180177178535 0.0048707172809282 2234.0924072048383 +r_1606 4-aminobenzoate transport 1.4387585958703104e-06 1.076338428472802e-08 0.7481021705533031 2.3440709011700384e-06 1.1588955762907178e-08 0.4943944211381393 5.447877068414605e-06 1.6166419553629508e-08 0.2967471429808551 8.098340451295276e-06 2.1702367604498333e-08 0.2679853697806342 1.141921549198649e-05 4.783953822534146e-08 0.418938921495204 1.3534791396601183e-05 3.917880482567012e-08 0.2894673709970039 1.5152735222525703e-05 7.134671727007697e-08 0.4708504189000452 1.7795814718847523e-05 1.0420894465519297e-07 0.5855811959248227 2.017821210077644e-05 1.0152161063331637e-07 0.5031249058453989 +r_1607 4-aminobutanal transport 0.0001458101253784 0.0039410676013795 2702.8764917042768 0.0001209437065622 0.0049365170678335 4081.665105322495 0.0001021855111817 0.0041709016967708 4081.6957791152254 0.000201278422821 0.0071139348881619 3534.375313784112 0.00130578510829 0.0255778176848113 1958.8075803916408 0.0002462427868652 0.010050844760993 4081.6808845220216 0.0006023576889763 0.0212904371332309 3534.5173678137094 0.0008395153347485 0.0297052479126686 3538.380620714243 0.0007968358203101 0.0286280799143992 3592.7200038844 +r_1608 4-aminobutyrate transport -0.0001458101253784 0.0039410676013795 -2702.8764917042768 -0.0001209437065622 0.0049365170678335 -4081.665105322495 -0.0001021855111817 0.0041709016967708 -4081.695779115224 -0.000201278422821 0.0071139348881619 -3534.375313784112 -0.00130578510829 0.0255778176848113 -1958.8075803916408 -0.0002462427868652 0.010050844760993 -4081.6808845220216 -0.0006023576891763 0.0212904371332265 -3534.517366639416 -0.0008395153351485 0.0297052479126571 -3538.3806190269524 -0.0007968358203101 0.0286280799143992 -3592.7200038844 +r_1609 4-hydroxy-2-oxoglutarate transport -2.8800000000000526e-10 4.5331787899870444e-10 -157.4020413189917 -9.729999999999678e-10 1.657603550281474e-10 -17.03600771101263 -7.614000000000406e-10 4.2673933647166247e-10 -56.046668830002574 -9.575999999999734e-10 2.0545238410985486e-10 -21.45492732976824 -3.4800000000000976e-10 4.763836566021588e-10 -136.89185534544407 -7.678000000000393e-10 4.2275158637284126e-10 -55.06011804803591 -8.08400000000025e-10 3.9461447530068126e-10 -48.81425968588187 -7.332000000000387e-10 4.423312010002092e-10 -60.32885992910335 -6.688000000000337e-10 4.711167054881907e-10 -70.44209113160387 +r_1610 4-hydroxy-2-oxoglutarate transport -7.138000000000373e-10 5.063011240019426e-10 -70.93039002548562 6.820000000000115e-10 1.368375127696332e-09 200.641514324972 -6.992000000000361e-10 4.91902178843215e-10 -70.35214228306485 7.212000000000173e-10 1.2121734335013992e-09 168.07729249880342 -5.048000000000253e-10 9.265790142961531e-10 -183.55368745960908 -6.380000000000331e-10 6.912680885981166e-10 -108.349230187787 1.1474000000000395e-09 1.1249561525984498e-09 98.04393869604418 1.454800000000026e-09 9.075911548383823e-10 62.38597434962648 6.908000000000138e-10 1.0648108397386452e-09 154.14169654583444 +r_1611 4-hydroxybenzoate transport -4.618376151469127e-11 2.6422007672892217e-10 -572.1060131597826 3.5685364048845377e-10 6.06295331492993e-10 169.9002791909615 3.8883311424753516e-10 1.3817228331548367e-09 355.35112173476506 4.883276723909482e-10 6.515116485217432e-10 133.41690126463948 2.7319099534011883e-10 6.91351290653328e-10 253.06518239834577 -7.380000000000045e-11 3.638406739318829e-10 -493.0090432681309 4.2362305476339165e-10 5.925736049066255e-10 139.8822840833341 3.532943424361764e-10 6.375267492597186e-10 180.45201201456825 6.300552477183587e-10 6.285605272350826e-10 99.7627635848302 +r_1613 5'-nucleotidase (AMP) 7.625935545722755e-05 0.0018040592705388 2365.689114105757 0.0001500459532362 0.0031084413434025 2071.659565858912 0.0001393814137962 0.0029090253826221 2087.097055046056 0.000173170389664 0.0036073633309253 2083.129418328165 0.000554467020249 0.0104910860636564 1892.102808737823 0.0004328611308248 0.0089313245785054 2063.3233022070303 0.0009429244403345 0.0163529603193193 1734.2810961096106 0.0013266211768209 0.0259578593151307 1956.6896540379173 0.0016098671333043 0.0280953073267022 1745.1941682314775 +r_1614 5'-nucleotidase (dAMP) -3.2199999999999944e-11 2.0584371335279383e-10 -639.266190536628 -1.4059999999999955e-10 3.633979246092502e-10 -258.4622507889412 -4.9999999999999885e-11 2.4312922976160257e-10 -486.2584595232063 -3.699999999999991e-11 2.0600846559688527e-10 -556.7796367483402 -1.8399999999999983e-11 1.6391099219599288e-10 -890.8206097608318 -3.639999999999992e-11 2.0948464565059347e-10 -575.5072682708625 -7.920000000000033e-11 3.1709220976538553e-10 -400.3689517239699 -1.7159999999999871e-10 4.0073127792999136e-10 -233.52638574009 -3.7199999999999895e-11 2.2677399606008768e-10 -609.6075162905599 +r_1615 5'-nucleotidase (dCMP) 7.381793191518009e-05 0.0023323701090347 3159.6253762767883 8.070588343803686e-05 0.0032898026794833 4076.2860640874906 9.082566021129117e-05 0.0032080282969631 3532.072642797428 0.0001340797753616 0.0047390198588759 3534.4777734689324 0.0001340627862602 0.0066895289664771 4989.847781838597 0.0002187125193028 0.0077303429423002 3534.4766577341147 0.0002014914435932 0.0100564001706259 4990.981250264464 0.0012224863627004 0.0305256186095705 2497.010972142032 0.0004405360035582 0.0179625408004686 4077.428554166502 +r_1616 5'-nucleotidase (dGMP) -1.3609033257663262e-10 3.527356589957199e-10 -259.19229699662463 -1.1840000000000018e-10 3.261942987608861e-10 -275.5019415210182 -1.94198317655269e-10 7.684054766605895e-10 -395.68081018323966 -5.819088602385657e-11 3.135109013346032e-10 -538.7628935673414 -1.4639999999999936e-10 3.5635998440859407e-10 -243.41528989658173 -1.4099999999999951e-10 3.5205651358516883e-10 -249.6854706277802 -1.8139999999999828e-10 3.9054390906655767e-10 -215.29432693856748 -2.2580000000000055e-10 4.22906762804749e-10 -187.292631888728 -1.7979999999999828e-10 3.88203684191809e-10 -215.9086118975599 +r_1617 5'-nucleotidase (dTMP) 0.0001014634496094 0.0025690222458813 2531.968167621027 0.0001844970449948 0.0046726399663287 2532.6367511522726 8.917868313963157e-05 0.0028198279788416 3161.9977774582203 9.555993575820784e-05 0.003420353096302 3579.275215249724 0.0004412836724922 0.0107476165954247 2435.534615347606 0.0002225524496474 0.0067829485317618 3047.797740491284 0.0002841351727331 0.010028269158294 3529.400834761451 0.0006973541997293 0.0191739464407129 2749.5276357632547 0.0005238142750678 0.0152252618916503 2906.6145418959813 +r_1618 5'-nucleotidase (dUMP) 7.37891882327752e-05 0.0023324855385098 3161.012601401432 0.0001611521079768 0.0046497225859048 2885.3005053912566 4.535445323057079e-05 0.0022674980493584 4999.504762699021 3.3545508407798355e-05 0.002372025898951 7071.068561893213 0.0002006622989141 0.0081903664756652 4081.666820318324 5.472211589579133e-05 0.0038693450909513 7070.898169069081 0.0003018364218962 0.0123199594892122 4081.6676171195786 0.000241991572953 0.0125041609447687 5167.188589329621 0.0004401038827025 0.0179635773519259 4081.667546674636 +r_1619 5'-nucleotidase (GMP) 0.0001140692703351 0.002599646144981 2279.006552196196 0.0002911865081743 0.0054557189007308 1873.6166503509228 8.124803222624924e-05 0.0025358216739417 3121.086879840188 0.0002286441048213 0.0052474549785817 2295.031828038001 0.0003432145089142 0.00930522826797 2711.198980895963 0.0003311102337238 0.0081662427933544 2466.321472915951 0.0009452233509379 0.0178995594413799 1893.6857012280789 0.0013463117919781 0.0279235671015745 2074.0787734277446 0.0010349252785927 0.0229576559072558 2218.2911541665203 +r_1620 5'-nucleotidase (XMP) -4.820470875306286e-11 4.611455943806769e-10 -956.6401422379224 -4.579999999999987e-11 3.021930246131203e-10 -659.8100974085614 -6.3324499362016e-11 4.2620247123579437e-10 -673.0451492387856 3.340911397720106e-11 3.822008811063659e-10 1144.0018474215935 -1.775949505286649e-11 4.522191303898032e-10 -2546.351284446076 -5.692103433006104e-11 3.848668511123717e-10 -676.1417034003484 -3.982689888370203e-11 5.068853758631284e-10 -1272.721176065647 -1.1275394787588472e-10 6.525459013472688e-10 -578.7344156371064 2.573803118432933e-11 5.629277223314447e-10 2187.143679716204 +r_1621 5-aminolevulinate exchange 1.8219999999999824e-10 4.5852503643945663e-10 251.660283446466 -5.199999999999999e-12 2.6755798895845713e-10 -5145.345941508792 -1.4400000000000002e-11 1.7719740343458599e-10 -1230.537523851291 9.200000000000807e-12 1.7413048063121715e-10 1892.7226155565425 4.800000000001009e-12 2.1350896284570566e-10 4448.103392617935 5.5799999999997975e-11 4.4757840127184125e-10 802.111830236304 2.0400000000001197e-11 2.2714347631347195e-10 1113.4484133012677 -1.499999999999946e-11 2.6455433808495113e-10 -1763.695587233071 9.800000000000872e-12 1.8791227262859856e-10 1917.472169679407 +r_1622 5-aminolevulinate transport -0.000111666174091 0.0011517148311508 -1031.3909655504117 -6.404717001076253e-05 0.0008480368071255 -1324.0816213785174 -0.0001153580141604 0.00134283872971 -1164.0619331761263 -0.0001114448779403 0.0016247479957375 -1457.8938267644355 -0.0003625825174417 0.0041041292660776 -1131.9159277272877 -0.0003087038247535 0.0037290410872725 -1207.9672450605694 -0.0003248540937801 0.0046597558536248 -1434.4150013325 -0.0007477574367461 0.008950356051309 -1196.9598176457628 -0.0007413068399591 0.0086513870396265 -1167.045354674423 +r_1623 5-formethyltetrahydrofolate cyclo-ligase 2.952929873820605e-05 0.0014762888446636 4999.403669392336 0.000241200671853 0.0056807898387599 2355.2131074578656 0.0001135041496323 0.0035878810967697 3161.013150966095 0.0002121287147669 0.0058574813565239 2761.286402436316 0.0001338653332263 0.0066925974257528 4999.500068054838 0.0001641628395752 0.0067005653926357 4081.657828271189 0.0005855254009109 0.0169363272888663 2892.500865464923 0.0001527101693142 0.0107982392341871 7071.067554096835 0.0004997715710868 0.0168994268999106 3381.430212838856 +r_1624 5-formyltetrahydrofolate:10-formyltetrahydrofolate isomerase 5.180076039208142e-10 5.76653779437639e-10 111.32148931269164 2.6847016891718784e-10 1.1623599214866882e-09 432.9568257712942 7.892993659817188e-11 1.166998683792472e-09 1478.524795647056 7.255698097985775e-10 4.737123761932974e-10 65.28832509235782 2.0559092103678572e-10 5.59097449251952e-10 271.9465657493283 4.754567278394197e-10 5.82967745267758e-10 122.61215608766167 2.8222511124107977e-10 4.929337526016808e-10 174.65977794605644 2.4277166706989065e-10 5.527052056637936e-10 227.66462509180587 8.835122577742436e-10 3.6204067394734637e-10 40.97743644886197 +r_1625 5-formyltetrahydrofolic acid exchange -1.3424476882824391e-11 1.5958519178525811e-09 -11887.628335777865 -6.735358083954202e-11 2.4409520928581157e-09 -3624.0865926241577 1.2254175215846348e-10 1.6340966317569784e-09 1333.5019313612102 -7.965331408164395e-10 7.692033188547562e-10 -96.56890334359842 -2.0677770457903015e-10 7.476245190839511e-10 -361.5595407667415 -4.710282754814631e-11 9.151076087717051e-10 -1942.786996887448 -1.69303876234277e-10 7.362293523789942e-10 -434.8567609640698 -1.2614964683829328e-10 7.89946618314688e-10 -626.1980418599921 -1.1528837949269623e-09 7.53382025350647e-10 -65.34761167307201 +r_1627 7,8-diaminononanoate exchange 9.987999999999587e-10 4.897999395632864e-11 4.903884056500868 9.851999999999635e-10 1.7025497746458775e-10 17.281260400385108 9.979999999999591e-10 6.322024485773655e-11 6.334693873520955 9.86799999999963e-10 1.6072002421987203e-10 16.28699069921748 9.991999999999587e-10 3.4635241012353085e-11 3.4662971389466093 9.985999999999587e-10 5.09760699931052e-11 5.104753654426927 9.989999999999588e-10 3.7406949300510186e-11 3.7444393694205935 9.979999999999591e-10 5.6538830266161824e-11 5.665213453523461 9.987999999999587e-10 4.8979993956328746e-11 4.903884056500877 +r_1628 7,8-diaminononanoate transport -9.987999999999587e-10 4.897999395632864e-11 -4.903884056500868 -9.851999999999635e-10 1.7025497746458775e-10 -17.281260400385108 -9.979999999999591e-10 6.322024485773655e-11 -6.334693873520955 -9.86799999999963e-10 1.6072002421987203e-10 -16.28699069921748 -9.991999999999587e-10 3.4635241012353085e-11 -3.4662971389466093 -9.985999999999587e-10 5.09760699931052e-11 -5.104753654426927 -9.989999999999588e-10 3.7406949300510186e-11 -3.7444393694205935 -9.979999999999591e-10 5.6538830266161824e-11 -5.665213453523461 -9.987999999999587e-10 4.8979993956328746e-11 -4.903884056500877 +r_1629 8-amino-7-oxononanoate exchange 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1630 9H-xanthine exchange 3.99140098840649e-06 0.0001261965027195 3161.7094620684347 1.2039114542160509e-05 0.0003803952424661 3159.661295139549 7.911502606328234e-06 0.0002795069712854 3532.918905466294 5.989496525239126e-06 0.0002991990371584 4995.395454319199 1.7734487195363933e-05 0.0007236124114263 4080.2556254095102 1.5156936008230684e-05 0.0004788693853866 3159.407581628997 1.7770852016947593e-05 0.0008881705211551 4997.906236055165 7.462294628448124e-05 0.0021906871700924 2935.674988951759 6.476117169784907e-05 0.0020469082520225 3160.702931028813 +r_1631 acetaldehyde exchange 0.0006573058122031 0.0080957873990435 1231.6622261270695 6.554409644367631e-05 0.001891156678219 2885.3196257639465 0.0003113909897077 0.0077901999089022 2501.7422360912137 7.492099829898235e-05 0.0030968287115954 4133.458952638542 0.000561406251624 0.0177461322877732 3161.0143699747296 0.0001773103166119 0.0089899325071027 5070.168887452546 0.0012911055615922 0.0279659480093809 2166.046591487985 0.0021224977077022 0.0472384189803528 2225.605182466493 0.0026149936721295 0.0559250177961609 2138.6291826327124 +r_1632 acetaldehyde transport -0.0004568801550017 0.0056938683633139 -1246.2498755920417 -0.009305172389166 0.1635768776004963 -1757.9134567237925 -0.0020257961942226 0.0208465509146597 -1029.0546983014065 -0.0011018536093896 0.0092205880863664 -836.8251469878901 -0.0360562354103227 0.609663312465299 -1690.8679054462657 -0.0043870547418872 0.0465510447977962 -1061.100158001928 -0.0022447884998188 0.0286754819132177 -1277.4246623025504 -0.0115763348075177 0.1693112481228728 -1462.5635050993997 -5.657118391562924 0.2351112340435254 -4.156024636043898 +r_1633 acetaldehyde transport -0.0006573058122031 0.0080957873990435 -1231.6622261270695 -6.554409644367631e-05 0.001891156678219 -2885.3196257639465 -0.0003113909897077 0.0077901999089022 -2501.7422360912137 -7.492099829898235e-05 0.0030968287115954 -4133.458952638542 -0.000561406251624 0.0177461322877732 -3161.0143699747287 -0.0001773103166119 0.0089899325071027 -5070.168887452546 -0.0012911055615922 0.0279659480093809 -2166.046591487985 -0.0021224977077022 0.0472384189803528 -2225.605182466493 -0.0026149936721295 0.0559250177961609 -2138.6291826327124 +r_1634 acetate exchange 9.601854562010268e-05 0.0009750919572187 1015.5246061283916 2.8121762517691228e-05 0.0004923526983791 1750.788906169775 0.0001095414821605 0.0010392661247568 948.7420694509246 8.637317128871613e-05 0.0009237667427812 1069.5065713095391 0.0001119876539994 0.0010523493777484 939.7012439904646 0.0001036188698025 0.0010112209192376 975.9042162538896 0.0001025068910123 0.0009977976160159 973.3956480013738 0.0001159687261709 0.0010705905173584 923.1717487181228 0.0001119454214394 0.0010519522402497 939.7009960058676 +r_1635 acetate transport 5.791478400000231e-10 1.216295606922934e-09 210.01470141421672 9.60550319954133e-10 1.6271388989684935e-09 169.39652875720145 7.980927992625757e-10 5.36181717842161e-10 67.18287877519809 9.25599999999984e-10 3.0932794370272143e-10 33.41918147177255 4.18925284342546e-10 8.56756078739542e-10 204.51285963417564 9.3759519999998e-10 3.4202499142007594e-10 36.4789614345384 9.540817999999742e-10 2.696010238318228e-10 28.257642461247045 8.976251999999934e-10 4.43158510939519e-10 49.370105801343605 9.124193999999887e-10 3.7189834898805926e-10 40.75958369452293 +r_1637 acetyl-CoA transport -5.791478400000231e-10 1.216295606922934e-09 -210.01470141421672 -9.60550319954133e-10 1.6271388989684935e-09 -169.39652875720145 -7.980927992625757e-10 5.36181717842161e-10 -67.18287877519809 -9.25599999999984e-10 3.0932794370272143e-10 -33.41918147177255 -4.18925284342546e-10 8.56756078739542e-10 -204.51285963417564 -9.3759519999998e-10 3.4202499142007594e-10 -36.4789614345384 -9.540817999999742e-10 2.696010238318228e-10 -28.257642461247045 -8.976251999999934e-10 4.43158510939519e-10 -49.370105801343605 -9.124193999999887e-10 3.7189834898805926e-10 -40.75958369452293 +r_1638 acetylcarnitine transport 1.2245590534822449e-05 0.0004998965513383 4082.257608702704 1.971708076970664e-05 0.0008219056286017 4168.495520211515 3.183251816143979e-05 0.0010062275789043 3161.005277060613 5.898067844301933e-05 0.0016245344261578 2754.350185590484 0.000110695447381 0.0031964599166014 2887.6164216555844 6.608059887225627e-05 0.0021946204709169 3321.1267881507906 0.0001617039750131 0.0046918777417737 2901.522823661288 0.0001575434808623 0.0056324468038982 3575.169707479185 0.0001645879982912 0.0058172970803757 3534.460070461753 +r_1639 adenine exchange -6.708765374774161e-10 1.563526296480941e-09 -233.0572332071717 -5.952000000000282e-10 5.533517865155531e-10 -92.96905015381836 -8.25400000000019e-10 3.900580329307424e-10 -47.25684915564978 -7.224000000000381e-10 4.636606908583504e-10 -64.1833735961138 -7.879009869952581e-10 4.744222359906035e-10 -60.21343339089624 -7.562228189837193e-10 4.947134181449262e-10 -65.4190016124833 -8.358000000000157e-10 3.7903442247199935e-10 -45.349895007417125 -8.39600000000014e-10 3.740318435160079e-10 -44.54881413959046 -8.016000000000273e-10 4.067806953467912e-10 -50.74609472888938 +r_1640 adenine transport -2.279999999999997e-11 1.5061439818086984e-10 -660.5894657055705 -1.52e-11 1.22359937850906e-10 -804.9995911243816 -3.559999999999991e-11 1.8530922238675386e-10 -520.5315235582989 -3.2199999999999925e-11 1.7654855954886122e-10 -548.2874520150982 -3.599999999999991e-11 1.8844389674501679e-10 -523.4552687361592 -3.0599999999999925e-11 1.7340603775759136e-10 -566.6863979006266 0.0 2.000200030005001e-11 0.0 0.0 -2.7799999999999942e-11 1.6562803666439928e-10 -595.7843045482 +r_1641 adenosine 3',5'-bismonophosphate exchange 2.9048872737774507e-06 9.3665914236058e-05 3224.4250949627017 7.081871596926531e-06 0.0002093677411519 2956.3899639587994 4.43812390023655e-06 0.0001811697390901 4082.124410282853 8.75056868235233e-06 0.0003093017195008 3534.6470695625785 2.353617099570695e-05 0.0006832116285233 2902.815537191352 9.92146666162271e-06 0.0003506883950029 3534.6426789844672 4.228021862548084e-05 0.0011333394726224 2680.5430753837827 5.233624775573602e-05 0.0015244329749262 2912.7670406198145 3.338731990144196e-05 0.0011909567936302 3567.0931274084223 +r_1642 adenosine 3',5'-bisphosphate transport -5.670629908253708e-05 0.0010281356848227 -1813.0890244244545 -0.0001949844769379 0.0023584902281762 -1209.5784573285223 -6.035675948030135e-05 0.0012811191233825 -2122.5777102905563 -0.0001566707941741 0.0023093454106142 -1474.011428094997 -0.0002719355356448 0.004730757659667 -1739.661441616702 -0.0001892708227335 0.0036235187074871 -1914.462385250448 -0.0005297792297927 0.0081481753936131 -1538.032247281792 -0.0007991506328638 0.0126607997106198 -1584.2820101698462 -0.0007247570069044 0.0116590330991631 -1608.6816668335168 +r_1643 adenosine exchange -5.054000000000214e-10 5.032111726669487e-10 -99.56691188502714 -3.7260000000001167e-10 4.839587618967563e-10 -129.88694629542167 -5.138841340602006e-10 5.120869645196865e-10 -99.65027728598764 -2.9280000000000565e-10 4.568477886346777e-10 -156.02725021675857 -3.8861689928196276e-10 5.620653772443001e-10 -144.63225307052105 -5.37400000000024e-10 5.006509465426623e-10 -93.16169455575734 -5.24400000000023e-10 5.026481582918664e-10 -95.85205154306723 -6.206894607115799e-10 6.581220785493906e-10 -106.03081254108886 -4.904000000000205e-10 5.027508246421251e-10 -102.5185205224519 +r_1644 ADP transport -0.0019696411107218 0.0116233361726913 -590.1245719039514 -0.0034716602297355 0.0209182754768085 -602.5438577669241 -0.0029772637257675 0.0178449242385264 -599.3733132904024 -0.0040533724670025 0.0252117480559845 -621.994358061754 -0.0089016785778748 0.052988990793554 -595.2696486397346 -0.0076650484743967 0.0444900100946095 -580.426989381967 -0.0128878914141901 0.0780296921491436 -605.4496398319254 -0.0195634751497943 0.1189296298814509 -607.9166864313515 -0.0198722990845115 0.1173548965480272 -590.545140494055 +r_1645 ADP transport -0.0003803107333211 0.0052597155800256 -1383.004769308998 -0.0005324128573221 0.0083959947535039 -1576.970698215744 -0.0004696439132222 0.0072196582858674 -1537.26218579796 -0.0007558386498005 0.0111346860693802 -1473.1564828443013 -0.0014969023699816 0.0220156976127222 -1470.7504012430868 -0.0012326201558393 0.0181161855908825 -1469.7297869956574 -0.0023187678591189 0.0340109491002604 -1466.7681789061871 -0.0034718310884414 0.051038608570209 -1470.0775259524794 -0.0030828917837914 0.0472009957308504 -1531.0623609629465 +r_1647 AKG transporter, peroxisome -3.407675673985924e-05 0.0008021713273068 -2354.013128158156 -6.876667228806635e-05 0.0015362493163629 -2234.002701086856 -6.22790995453006e-05 0.0013092882100191 -2102.291490368814 -0.0001109160186732 0.0021299674451819 -1920.34249936181 -0.0001397886732644 0.0034057095825964 -2436.327281076364 -0.0001119133835982 0.0027953978417021 -2497.822648037609 -0.0002299650774346 0.0054166173427311 -2355.4086573299014 -0.0002900860411642 0.0073918722780611 -2548.165450634197 -0.0001860408993261 0.0058815242113138 -3161.414631200489 +r_1648 allantoate exchange -1.055462520848105e-09 5.312851503770411e-10 -50.33671398868172 1.864875109276373e-10 7.090642746839824e-10 380.2207832347125 1.4464215544683956e-11 7.633938638926856e-10 5277.810341904483 2.5420303173024157e-10 8.24926478562747e-10 324.5148072970872 4.62023884136954e-12 5.383096040504201e-10 11651.120700306774 -5.998418993903247e-10 9.49184371268168e-10 -158.23909137272875 1.5106028801395455e-11 6.236435447153972e-10 4128.441385321514 -1.5838688520048864e-10 7.193068138778396e-10 -454.145438220677 9.473496284703863e-11 7.779905977181183e-10 821.2285879863389 +r_1649 allantoin exchange -2.598750189528791e-11 5.155614295942667e-10 -1983.8822202750816 1.3278195640909874e-10 3.852401851883904e-10 290.12992096717755 3.7041856318000177e-10 6.109429714930924e-10 164.93314110616254 3.0931762492897795e-10 5.131800347903975e-10 165.9071431536526 5.430916588864523e-10 5.42184706033957e-10 99.8330018814218 -4.4628878187440565e-10 7.753767343181814e-10 -173.73879107191803 8.062832296192415e-10 6.648132015682945e-10 82.45405301090605 6.93254196704578e-10 7.937470785429286e-10 114.4958201935234 6.187190154972993e-10 7.160351600726377e-10 115.72864937682904 +r_1650 trehalose exchange -3.531639191681797e-10 5.539593557832913e-10 -156.85615820779552 -9.179256125556156e-11 1.3785883781311714e-09 -1501.8519575818518 -1.8359999999999816e-10 5.789283821115633e-10 -315.3204695596781 -3.93999999999999e-11 4.559487008903073e-10 -1157.2302053053518 -4.800877052236587e-10 5.63689943173283e-10 -117.41395104269046 1.1257125990116252e-11 6.28397777920468e-10 5582.222127319184 -3.924000000000131e-10 5.835154994236347e-10 -148.7042557144789 -4.716545418369185e-10 8.629845013413577e-10 -182.9696154266541 -4.732000000000191e-10 5.665209168158119e-10 -119.72124193064008 +r_1651 alpha-D-glucosamine 6-phosphate exchange 9.192153645259462e-06 0.0003752242021263 4082.005334188859 2.481069649440992e-05 0.0006627111688963 2671.0703951646065 2.943582333517809e-05 0.0009304904010142 3161.081619559124 3.354505390423862e-05 0.0011856560022504 3534.518101044615 5.209005860471113e-05 0.0021261699311339 4081.7192149245593 1.56161565118214e-05 0.0008576368225609 5491.984035326957 1.3521652279311522e-05 0.0009561622012975 7071.341442203023 7.922362201792214e-05 0.0039605680096619 4999.226125720398 7.610658210769479e-05 0.0038049673386131 4999.524657708267 +r_1652 alpha-ketoglutarate/malate transporter 1.665659344422369e-05 0.0005887451116107 3534.6069625955784 7.922199600535473e-06 0.0005602077727156 7071.3665517565805 1.889689741358524e-05 0.0013361402896286 7070.686051711854 2.310640680401245e-05 0.0016338970256326 7071.18609782706 -8.318538037823024e-07 0.0101273180107207 -1217439.6468073465 1.5433844313194618e-05 0.001091354755206 7071.178982109091 0.0003958747624084 0.0114615416750349 2895.244345788576 0.0003461593465699 0.011117815947352 3211.762460703767 0.000128430142979 0.0090813981876907 7071.080026105591 +r_1654 ammonium exchange -0.1070455079069648 0.0077688261674395 -7.25749853435384 -0.1815740231076238 0.0094036821512385 -5.178979894973608 -0.6302842679926176 0.0781677004285948 -12.401975489178856 -0.7890728237744653 0.0483010931633514 -6.121246570412492 -1.4896039826253766 0.3023623589602088 -20.2981706874404 -1.1952209189947711 0.0330153892888201 -2.762283420925012 -1.8978397552170816 0.2675560718381974 -14.0979274516037 -2.1110801122337093 0.236130339843291 -11.185285602138723 -3.269441725835264 0.6984241421996574 -21.362183539797662 +r_1656 AMP transport 8.755184442741751e-10 2.090791964485992e-09 238.8061585863341 1.409118600079129e-09 2.4728418887075798e-09 175.48855636202072 1.3398191463196774e-09 1.214152744508465e-09 90.62064442380876 1.255399999995562e-09 9.875048724825518e-10 78.66057611008785 5.483252843426565e-10 1.6737940242473243e-09 305.2556706834889 1.4974929063419767e-09 9.68177574704873e-10 64.65323278691872 1.398881800000063e-09 9.64291417267729e-10 68.93301616102843 1.5504252000000746e-09 1.0219940220770162e-09 65.91701567266627 1.6954194000000252e-09 9.032967003645086e-10 53.27865779785787 +r_1657 arginine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1658 asparagine transport 4e-13 1.9997999499871067e-11 4999.499874967767 2e-13 1.4142135623729562e-11 7071.06781186478 6.000000000000003e-13 2.4489996978163404e-11 4081.666163027234 0.0 0.0 0.0 0.0 -1.6885941672706298e-13 1.1940163863490883e-11 -7071.067811865328 0.0 0.0 0.0 0.0 -1.355768996016195e-13 2.1945559443444803e-11 -16186.798420623169 +r_1659 aspartate-glutamate transporter 7.3920859215260735e-06 0.000926882430664 12538.848174977073 6.475791856084145e-06 0.0017400434930222 26869.972532972555 4.30169495889769e-06 0.001495253119552 34759.62693401283 -9.22839069662027e-06 0.0023974489839807 -25979.05813479193 7.865111692807987e-05 0.004087554278768 5197.070859789346 7.016389128225419e-05 0.0033611465984387 4790.422163043297 0.000194982529027 0.0066589009901241 3415.126997967858 0.0001805463636086 0.0089051257847062 4932.320766099301 0.0003015735507947 0.0076999572044007 2553.260119830772 +r_1660 ATP diffusion 0.0019696415502183 0.0116233362163493 590.1244424428867 0.0034716606915355 0.0209182755181729 602.5437788080771 0.0029772644627676 0.0178449242618792 599.3731657042923 0.0040533730546026 0.0252117480761684 621.9942683918629 0.0089016792203981 0.0529889907896695 595.2696056295295 0.0076650488538967 0.0444900101210087 580.4269609891775 0.01288789188349 0.078029692185022 605.4496180634615 0.0195634757640939 0.1189296299050165 607.9166674630246 0.0198722997166342 0.1173548965654718 590.5451217970452 +r_1661 ATP transport 0.0003803107333211 0.0052597155800258 1383.0047693089978 0.0005324128573221 0.0083959947535039 1576.970698215744 0.0004696439132222 0.0072196582858673 1537.26218579796 0.0007558386498005 0.0111346860693802 1473.1564828443013 0.0014969023699816 0.0220156976127222 1470.7504012430868 0.0012326201558393 0.0181161855908825 1469.7297869956574 0.0023187678591189 0.0340109491002604 1466.7681789061871 0.0034718310884414 0.051038608570209 1470.0775259524796 0.0030828917837914 0.0472009957308504 1531.0623609629465 +r_1663 bicarbonate exchange 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1664 bicarbonate formation -7.600000000000002e-12 9.769415965024004e-11 -1285.4494690821057 -9.000000000000004e-12 9.444990289476612e-11 -1049.443365497401 -7.000000000000001e-12 9.875702805430514e-11 -1410.8146864900732 -3.8e-12 8.115957969010801e-11 -2135.7784128975795 -5.999999999999998e-12 8.925017153274383e-11 -1487.5028588790644 -1.6e-12 6.927048202471001e-11 -4329.405126544376 -1.0400000000000007e-11 1.1087965935992347e-10 -1066.1505707684942 -1.0200000000000007e-11 1.1357173815673423e-10 -1113.4484133013152 -1.4e-12 7.070388820963914e-11 -5050.2777292599385 +r_1665 bicarbonate formation 0.0012621740311194 0.012475740496861 988.4326716653918 0.0049054082110193 0.0336027172118685 685.0136780948083 0.01146112332557 0.0626284953387334 546.4429058101828 0.0296427105705034 0.1514679255314654 510.9786609129685 0.0210880457757667 0.126453780816199 599.646748498207 0.0296170178124813 0.1613186663610124 544.68234236949 0.0269962871942117 0.1938751020061765 718.1546877592315 0.0145748523064043 0.1911526062988158 1311.5234534131184 0.0580142558124267 0.3290041658411891 567.1091721057913 +r_1667 bicarbonate formation 0.0725291361995541 0.0216250128272541 29.81562163894499 0.1202358937240598 0.0455482862264271 37.88243661327957 0.2963344246956809 0.0678678794972273 22.902462164807176 0.710840477265255 0.1780986362077543 25.054655988771955 0.5873795939684107 0.1623340689235577 27.63699498425001 0.7306929472548562 0.1622177206003263 22.200531866328102 0.8688210519375376 0.2105794231852879 24.23737577671256 1.0810204120198277 0.2302374967137108 21.2981636751451 1.2003755867253738 0.3589535029844432 29.903432471804003 +r_1668 bicarbonate formation 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1669 bicarbonate transport -0.0012621740311194 0.012475740496861 -988.4326716653918 -0.0049054082110193 0.0336027172118685 -685.0136780948083 -0.01146112332557 0.0626284953387334 -546.4429058101828 -0.0296427105705034 0.1514679255314654 -510.9786609129685 -0.0210880457757667 0.126453780816199 -599.646748498207 -0.0296170178124813 0.1613186663610124 -544.68234236949 -0.0269962871942117 0.1938751020061765 -718.1546877592315 -0.0145748523064043 0.1911526062988158 -1311.5234534131184 -0.0580142558124267 0.3290041658411891 -567.1091721057913 +r_1671 biotin exchange -9.987999999999587e-10 4.897999395632864e-11 -4.903884056500868 -9.851999999999635e-10 1.7025497746458775e-10 -17.281260400385108 -9.979999999999591e-10 6.322024485773655e-11 -6.334693873520955 -9.86799999999963e-10 1.6072002421987203e-10 -16.28699069921748 -9.991999999999587e-10 3.4635241012353085e-11 -3.4662971389466093 -9.985999999999587e-10 5.09760699931052e-11 -5.104753654426927 -9.989999999999588e-10 3.7406949300510186e-11 -3.7444393694205935 -9.979999999999591e-10 5.6538830266161824e-11 -5.665213453523461 -9.987999999999587e-10 4.8979993956328746e-11 -4.903884056500877 +r_1672 carbon dioxide exchange 1.0878312456289445 0.0131901949654772 1.212522164488041 1.8150643064074967 0.0024879646853925 0.1370730875269602 3.1153451171155777 0.0052721566772371 0.1692318661027995 4.500352280109244 0.0023311246394831 0.0517987147314296 6.869626701659776 0.0141225500439276 0.2055795847031318 7.863635667654601 0.0346783309933805 0.4409961557097881 9.905782332705652 0.0176472536334336 0.1781510338175738 14.188830630078312 0.0272569513561989 0.1921014639389525 16.686949270816335 0.0074177979578953 0.0444526907675582 +r_1673 carnitine transport 1.2245590534822449e-05 0.0004998965513383 4082.257608702704 1.971708076970664e-05 0.0008219056286017 4168.495520211515 3.183251816143979e-05 0.0010062275789043 3161.005277060613 5.898067844301931e-05 0.0016245344261578 2754.350185590485 0.000110695447381 0.0031964599166014 2887.6164216555844 6.608059887225627e-05 0.0021946204709169 3321.1267881507915 0.0001617039750131 0.0046918777417737 2901.5228236612875 0.0001575434808623 0.0056324468038982 3575.169707479185 0.0001645879982912 0.0058172970803757 3534.460070461753 +r_1674 carnitine-acetylcarnitine carrier 4.571924377335683e-05 0.0009297436988803 2033.5937827172063 0.000136898976447 0.0021837761203356 1595.1734461506237 9.210324837336954e-05 0.0016245417903383 1763.8268128749469 0.0001570466838422 0.0026093352338975 1661.502917513915 0.0002455465193463 0.0046000168331632 1873.3789611065497 0.0002230318782188 0.0038130788444852 1709.6564289089954 0.000477515194532 0.0079591199660683 1666.7783679363058 0.0006387156618233 0.0111178874876358 1740.6630449450342 0.0005481080603984 0.0102018593992314 1861.2861470812609 +r_1675 CDP transport 6.351830073661085e-10 6.042677714280681e-10 95.13286161948264 5.032296732760513e-10 6.324306261773904e-10 125.67435104933983 7.272055395166702e-10 5.291769669780104e-10 72.76855554891982 4.5840000000001824e-10 6.002845227903621e-10 130.95212102756065 5.09000000000022e-10 6.48384978709495e-10 127.38408226119196 5.10000000000022e-10 6.062784135221655e-10 118.87812029845873 4.874209602121212e-10 6.328938597198691e-10 129.84543369748388 6.820000000000353e-10 5.6686882790785e-10 83.1185964674224 4.236000000000157e-10 6.342266855768157e-10 149.72301359225503 +r_1676 ceramide transport -0.0001630315453657 0.00207470847531 -1272.5810030538692 -0.0002927873667938 0.0037917068542384 -1295.0377250765616 -0.0002315123984997 0.0031173736055607 -1346.5255536041204 -0.0002938879233328 0.0042418622012475 -1443.3605005411637 -0.0007804526269344 0.0098291856448919 -1259.4211750558184 -0.0005039135250021 0.007088819816413 -1406.753235365646 -0.0008195050167775 0.0123137277499595 -1502.5811310318754 -0.0017466361591735 0.022150942735998 -1268.2058950662597 -0.0016924988913088 0.0213409268107768 -1260.9123066705774 +r_1677 ceramide transport -0.0001152038409985 0.001774881168128 -1540.644090287538 -0.0001827467283183 0.0030133179981414 -1648.9039370883172 -0.0001533909676211 0.0025377443150818 -1654.4287805459874 -0.0002378702859452 0.0038107029266048 -1602.008805539496 -0.0006811379019642 0.0092159691848393 -1353.0254531810317 -0.0003971438570669 0.0062103508687872 -1563.753475794119 -0.000791915355894 0.012177321037407 -1537.7048754988114 -0.0010252873419319 0.0170460397091096 -1662.5621922718 -0.0011875369404613 0.0179121724961434 -1508.346552081491 +r_1678 ceramide transport -0.0001055040768085 0.0016885517012285 -1600.461093359107 -0.0003006804040301 0.0038337301822339 -1275.0183021071773 -0.0002040190066278 0.0029095729786115 -1426.1283920077294 -0.0003046971767589 0.0043307139312538 -1421.3173805284805 -0.0007131544114361 0.0093162972357173 -1306.3506424864945 -0.0006736979215761 0.0081876023068064 -1215.3224827607046 -0.0010716978833303 0.013992162538044 -1305.606995747922 -0.0014575614117451 0.0202239883155224 -1387.5222102173695 -0.0016070168069594 0.0207473064629355 -1291.0447714725672 +r_1679 ceramide transport -0.0001874377011473 0.0022491548893091 -1199.9479696673393 -0.0002383691422287 0.0034192908473145 -1434.4519661161216 -0.0001545137923884 0.0025493821108416 -1649.9382167983547 -0.0004230338487285 0.005037557642798 -1190.8166823858287 -0.0007327876560142 0.0094788578364819 -1293.534048872885 -0.0006523180839399 0.0081295783567864 -1246.2598472949044 -0.0009740552714395 0.0134178148022133 -1377.5208856867628 -0.0017295321017524 0.0217146045302403 -1255.519022066041 -0.0015585618296854 0.0204599089885844 -1312.7428504208322 +r_1680 ceramide transport -0.0001380622436061 0.0019476828813786 -1410.7281111079787 -0.0003661856929189 0.0042504913579726 -1160.7475224090033 -0.0002926288211224 0.0034405500205455 -1175.738605428182 -0.0003056287523002 0.0043619090500081 -1427.191982815444 -0.0008690310433434 0.0102435664765381 -1178.7342414291477 -0.0005064367451185 0.0070475384781475 -1391.593036263265 -0.0012421472072065 0.0151260083766153 -1217.730739871949 -0.0016362124472625 0.021383376522715 -1306.8826458624258 -0.001404752110643 0.0194691246238933 -1385.947348032917 +r_1681 ceramide transport -0.0001595690576751 0.0020768141640802 -1301.5143376410906 -0.0002800925575415 0.003721310469685 -1328.600267835831 -0.0002187435061331 0.0030153741012976 -1378.4976544453975 -0.0003842465909368 0.0048204668523019 -1254.524299239272 -0.0006259281804722 0.0087778027178025 -1402.365797171881 -0.000613138808002 0.0078702232477088 -1283.5956793134776 -0.0013172463468581 0.0155736750310079 -1182.290242683444 -0.0018592204233313 0.0227001285116197 -1220.948749634839 -0.001838467080139 0.0220954901900789 -1201.843124023057 +r_1682 cholestenol delta-isomerase, lumped reaction 0.000839641547689 6.696778332055928e-05 7.975758644253913 0.0013671615601396 8.930810059380819e-05 6.532373583169182 0.0031717086439138 0.0001439456050071 4.538424589642288 0.0047144401282498 0.0002114535680493 4.485231804775541 0.0066535444231789 0.0003643032034768 5.475325334985828 0.0078773001606155 0.0003794709317292 4.817271450776041 0.0088218960162068 0.0004796574191553 5.4371239274886936 0.0103652423663271 0.0006880958508314 6.638492632519996 0.0117579298032428 0.000660813740002 5.620153811598283 +r_1683 choline exchange 0.0001353640974921 0.0007685648562741 567.7759985943059 0.0001701943250482 0.0009802098033181 575.9356565150002 0.0002292389593484 0.0012679146578736 553.0973711786166 0.0003335694856792 0.001839925335671 551.5868251331558 0.0006595867271303 0.0037187086849935 563.7937411464517 0.0005211517646182 0.0028726597314348 551.2136629795206 0.0010573149035065 0.0057731235892943 546.017423016344 0.0015117478763524 0.0085598835557618 566.224281817107 0.0015064114794079 0.0083711253010404 555.6997815982096 +r_1684 choline transport 0.0004814877402456 0.0030870195625188 641.1418826457012 0.000903976441491 0.0059330794683168 656.3312046639694 0.0008417365907375 0.0049815065563498 591.8129984090407 0.0011083082105804 0.0067878660699381 612.4529264637491 0.0025130657253996 0.0150632848865976 599.3987636038386 0.0021680705448369 0.0126144913484613 581.8302996875094 0.0037538611775678 0.0222535640504139 592.817981213472 0.0059560705298748 0.0353994831358289 594.3429138098669 0.0057639349549195 0.0339332086204119 588.7160227484827 +r_1685 chorismate pyruvate lyase -4.618376151469127e-11 2.6422007672892217e-10 -572.1060131597826 3.5685364048845377e-10 6.06295331492993e-10 169.9002791909615 3.8883311424753516e-10 1.3817228331548367e-09 355.35112173476506 4.883276723909482e-10 6.515116485217432e-10 133.41690126463948 2.7319099534011883e-10 6.91351290653328e-10 253.06518239834577 -7.380000000000045e-11 3.638406739318829e-10 -493.0090432681309 4.2362305476339165e-10 5.925736049066255e-10 139.8822840833341 3.532943424361764e-10 6.375267492597186e-10 180.45201201456825 6.300552477183587e-10 6.285605272350826e-10 99.7627635848302 +r_1686 citrate transport -1.25247894872574e-05 0.0004427062310608 -3534.6400952390354 -2.0552207627396835e-05 0.0008325607581311 -4050.9553680320055 -2.65069694108552e-05 0.0013293466402187 -5015.083465838996 -0.0001666004474476 0.0041678544641222 -2501.706644835148 -0.000208158447046 0.007086212755511 -3404.23982599315 -2.3300282857749664e-05 0.0011649069371907 -4999.539895299019 -0.0001052104682649 0.0052599981485805 -4999.50074866545 -0.0001586599486171 0.0061998168025419 -3907.613015494725 -0.0006604841717511 0.0190569992509503 -2885.307485934656 +r_1687 citrate exchange 1.25247894872574e-05 0.0004427062310608 3534.6400952390354 2.0552207627396835e-05 0.0008325607581311 4050.9553680320055 2.65069694108552e-05 0.0013293466402187 5015.083465838996 0.0001666004474476 0.0041678544641222 2501.706644835148 0.000208158447046 0.007086212755511 3404.239825993151 2.3300282857749664e-05 0.0011649069371907 4999.539895299019 0.0001052104682649 0.0052599981485805 4999.50074866545 0.0001586599486171 0.0061998168025419 3907.613015494725 0.0006604841717511 0.0190569992509503 2885.307485934656 +r_1688 citrate/isocitrate antiport -4.146883606685555e-05 0.0004613084260999 -1112.4219289786645 -7.524246414415254e-05 0.0008107644139629 -1077.535701661243 -6.658069798960114e-05 0.0007164160476346 -1076.0116208853028 -0.0001016875564853 0.0010901555628875 -1072.0638793639594 -0.0002184397594764 0.0022468108618578 -1028.5723016920836 -0.0001820772742585 0.0018554821016763 -1019.062982589174 -0.0004249476078171 0.0038478219310236 -905.4814900098428 -0.0004706323984852 0.0049384599682345 -1049.324267544994 -0.0004876144393144 0.0049513175031828 -1015.4165061527076 +r_1689 citrate/malate antiport 0.0009199279137473 0.0037722514441627 410.0594609415145 0.0019526888072263 0.0074804640334084 383.0853132217259 0.0015007158760363 0.0062141947563313 414.0820294874172 0.0023417407869893 0.0093823703147592 400.65793647561856 0.004552246679021 0.0189419151081695 416.10036634137424 0.0036803444674375 0.0141838443990372 385.3944793627633 0.0066504013598507 0.0273198897291614 410.8006156454655 0.0110455222170748 0.0438170667371801 396.6952931337645 0.0100744604163594 0.0410528999378204 407.4947763073907 +r_1690 CMP nucleosidase 1.6421622348402302e-05 0.0005804177418451 3534.472596744611 2.2272507482565403e-05 0.0009090903837831 4081.670572991321 2.06502746213858e-05 0.0008428748729096 4081.6642314131145 3.0532271847277204e-05 0.0012462282142442 4081.675351503251 3.885758754411134e-05 0.0019426884774905 4999.5087195911065 3.3326186409665054e-05 0.0016661219760507 4999.437846172436 5.870443998169136e-05 0.0028930254771462 4928.1203909763935 0.0001649763278879 0.0058468120831674 3544.0309273580283 8.367827722412597e-05 0.0041834904318035 4999.493979301669 +r_1691 CO2 transport 1.9469628306220782e-10 1.6315599867639483e-09 838.0026372884813 2.860679584993173e-10 2.3729727480216482e-09 829.5136444046427 2.5970333427871677e-10 1.7655281247457551e-09 679.8249740032096 3.565839694956145e-10 2.372366450292009e-09 665.3037301838621 3.444606466973953e-10 2.127516978119177e-09 617.6371665434909 2.1608373516605822e-10 2.019144946076345e-09 934.4270842618728 2.53567309746474e-10 1.7687947082476455e-09 697.5641734008032 2.1988151777847176e-10 1.77847019372856e-09 808.8311431069661 1.8896275510042327e-10 1.549206181510308e-09 819.8473718733569 +r_1694 CO2 transport -0.0012621740311194 0.012475740496861 -988.4326716653918 -0.0049054082110193 0.0336027172118685 -685.0136780948083 -0.01146112332557 0.0626284953387334 -546.4429058101828 -0.0296427105705034 0.1514679255314654 -510.9786609129685 -0.0210880457757667 0.126453780816199 -599.646748498207 -0.0296170178124813 0.1613186663610124 -544.68234236949 -0.0269962871942117 0.1938751020061765 -718.1546877592315 -0.0145748523064043 0.1911526062988158 -1311.5234534131184 -0.0580142558124267 0.3290041658411891 -567.1091721057913 +r_1695 CO2 transport -4.1468842661388153e-05 0.0004613084255072 -1112.421750647813 -7.524246414415254e-05 0.0008107644139629 -1077.535701661243 -6.658079450419674e-05 0.0007164160386695 -1076.0100476487669 -0.0001016876279765 0.0010901555562186 -1072.0631190939985 -0.0002184397901925 0.0022468108588711 -1028.5721556914298 -0.0001820772748804 0.0018554821016152 -1019.062979074714 -0.0004249476064617 0.0038478219311734 -905.481492933178 -0.0004706324047729 0.0049384599676355 -1049.324253398613 -0.0004876144501209 0.0049513175021185 -1015.4164834308284 +r_1696 CO2 transport -0.9283052430734766 0.1281223045254065 -13.801743066883168 -1.7151911553256889 0.2546712416257033 -14.847980112009452 -2.413065412085067 0.3489956465982613 -14.46275118985288 -4.2797336717940135 0.5641421418542603 -13.181711412845427 -5.66514050793795 1.0675033524209907 -18.84336939084235 -6.2715546893039855 0.8109544711081816 -12.930676862170214 -8.298232988840878 1.24360023989847 -14.986325903006248 -10.18513826693836 1.7591956243005078 -17.272182057763267 -8.859295070534627 1.6173950437840932 -18.256475610158105 +r_1697 CO2 transport 1.0878312456289445 0.0131901949654772 1.212522164488041 1.8150643064074967 0.0024879646853925 0.1370730875269602 3.1153451171155777 0.0052721566772371 0.1692318661027995 4.500352280109244 0.0023311246394831 0.0517987147314296 6.869626701659776 0.0141225500439276 0.2055795847031318 7.863635667654601 0.0346783309933805 0.4409961557097881 9.905782332705652 0.0176472536334336 0.1781510338175738 14.188830630078312 0.0272569513561989 0.1921014639389525 16.686949270816335 0.0074177979578953 0.0444526907675582 +r_1698 coenzyme A transport -0.0001462906149089 0.0024292961582018 -1660.5960400902263 -0.0001686918089754 0.0036069979284125 -2138.2175876347164 -0.0001822523238148 0.0031069368032985 -1704.7446848772356 -0.0005124641985424 0.0065647779744904 -1281.0217754063858 -0.0004335022738941 0.0087857054408651 -2026.680359007736 -3.5212990197789494e-05 0.0007333548116516 -2082.6257796696045 -0.000878410679268 0.0159754702413032 -1818.678963991493 -0.000873846551318 0.0191451213648674 -2190.901976552904 -0.0010693414506597 0.0208449083034856 -1949.322014088675 +r_1699 coenzyme A transport 5.791478400000231e-10 1.216295606922934e-09 210.01470141421672 9.60550319954133e-10 1.6271388989684935e-09 169.39652875720145 7.980927992625757e-10 5.36181717842161e-10 67.18287877519809 9.25599999999984e-10 3.0932794370272143e-10 33.41918147177255 4.18925284342546e-10 8.56756078739542e-10 204.51285963417564 9.3759519999998e-10 3.4202499142007594e-10 36.4789614345384 9.540817999999742e-10 2.696010238318228e-10 28.257642461247045 8.976251999999934e-10 4.43158510939519e-10 49.370105801343605 9.124193999999887e-10 3.7189834898805926e-10 40.75958369452293 +r_1700 coenzyme A transport 0.000313635605271 0.0032169688211245 1025.702683961698 0.0007308494200777 0.0060242948598032 824.2867401006265 0.0004053782739747 0.004610039411356 1137.2191622787532 0.0006009408704965 0.0066839206889851 1112.2426543334436 0.0011354474865822 0.0131319953886303 1156.5480168667889 0.0009006358523265 0.0112731019576818 1251.6825672174812 0.0023269783048751 0.0217421629693984 934.351769582352 0.0020892196337429 0.0268627946100685 1285.7812637890236 0.0026288387255055 0.0290274181776807 1104.1916682088822 +r_1702 cytidine exchange -7.855227234414562e-11 6.33345657577816e-10 -806.272866051619 -7.760618123978617e-11 5.727907458998788e-10 -738.0736131443967 1.0342148100195847e-11 6.668572999424088e-10 6447.957363226897 -4.6645385356034194e-11 5.580426213967397e-10 -1196.3511870195102 1.405350418466859e-11 6.240665732241195e-10 4440.647435853994 -6.033294831115866e-12 5.745283971886e-10 -9522.630888607517 9.408516946506262e-13 6.130662961085616e-10 65160.779280544986 -8.672853760418222e-11 6.190765329402143e-10 -713.8094911338171 3.679399581843211e-11 5.785131460928981e-10 1572.303125074253 +r_1703 cytidylate kinase (CMP) 0.0027454198141113 0.0074489201897466 271.32171740946416 0.0048791132254217 0.013271536655796 272.0071464348681 0.0051651966166125 0.0109610399528014 212.20953946938067 0.0075284615354612 0.0164140278336186 218.0263225933168 0.0147372529722899 0.0352885949100912 239.45164662941943 0.0131362185434636 0.0284356387500766 216.46746098195712 0.0215769661832407 0.0522834503246302 242.3114068985276 0.0311236318458493 0.0820031394916942 263.4754835099043 0.0305654756754896 0.0780710905714272 255.42246225872444 +r_1704 cytidylate kinase (dCMP) -0.0001210991631997 0.0011119180281927 -918.1880359969996 -0.000131972009333 0.0030505088795662 -2311.4817263011096 -0.0004361999632071 0.0025819996202287 -591.9302700634107 -0.0006645687774222 0.0035450110121355 -533.4302682539588 -0.0008842879634205 0.0077184636664371 -872.845044342953 -0.0010543371502923 0.0066399608406153 -629.7758585831849 -0.0011728350419967 0.0097015211138994 -827.1854750675345 -0.0012262794619862 0.017523257204647 -1428.9774678493218 -0.0013591654930298 0.0179563852743817 -1321.1331045753188 +r_1705 cytosine exchange 9.807927194690756e-11 1.0243932090333287e-09 1044.454336475759 7.459242063412872e-11 1.039598048158631e-09 1393.7046677407034 9.498169887658554e-11 9.798950443991487e-10 1031.6672116724037 5.7331246163207646e-11 9.551552155958626e-10 1666.0290496333807 1.0340178940705162e-10 1.1052016798711258e-09 1068.8419283735868 1.1459595094759394e-10 8.50599742722821e-10 742.2598579524073 9.371005539397092e-11 1.054271721064457e-09 1125.035853017206 8.954896009512705e-11 1.1978048400707835e-09 1337.5977105690183 2.4775054591156477e-10 1.658669646250706e-09 669.4918229737312 +r_1706 D-arabinose exchange -8.800000000000005e-12 1.2134869220976904e-10 -1378.9624114746475 -1.4e-12 6.163440402852683e-11 -4402.457430609059 -6.000000000000003e-13 4.2426406871193215e-11 -7071.067811865535 -2.0000000000000004e-12 5.288250478052487e-11 -2644.1252390262425 -2.000000000000001e-13 8.124826309559379e-11 -40624.13154779688 -6.000000000000003e-13 1.1046302737153455e-10 -18410.504561922426 1.5399999999999997e-11 1.7311508821229523e-10 1124.123949430489 -4.999999999999991e-11 2.985260852332841e-10 -597.0521704665692 4.000000000000001e-13 5.6572785825160576e-11 14143.19645629014 +r_1707 D-arabinose transport 8.800000000000005e-12 1.2134869220976904e-10 1378.9624114746475 1.4e-12 6.163440402852683e-11 4402.457430609059 6.000000000000003e-13 4.2426406871193215e-11 7071.067811865535 2.0000000000000004e-12 5.288250478052487e-11 2644.1252390262425 2.000000000000001e-13 8.124826309559379e-11 40624.13154779688 6.000000000000003e-13 1.1046302737153455e-10 18410.504561922426 -1.5399999999999997e-11 1.7311508821229523e-10 -1124.123949430489 4.999999999999991e-11 2.985260852332841e-10 597.0521704665692 -4.000000000000001e-13 5.6572785825160576e-11 -14143.19645629014 +r_1708 D-erythrose 4-phosphate transport 0.0052036040195815 0.0018701166319442 35.93887284479828 0.0085591365412619 0.0016032650909514 18.73162185487317 0.0234086327463921 0.0029191679314326 12.47047601224208 0.0390438620665965 0.003828058293807 9.80450726743578 0.0427175648851997 0.0072635454484343 17.00365053100416 0.0591844219041012 0.0072112578109409 12.18438497654951 0.0690375188209769 0.0111956780611244 16.21680247541383 0.0871159029810305 0.0171509635680712 19.68752315154885 0.0918926165263695 0.0156337565318725 17.013071477169557 +r_1709 D-fructose exchange 6.479940980343314e-10 2.109763147337081e-09 325.58369802085804 1.40459999999438e-09 8.858079764592274e-10 63.06478545228335 1.7345999999999727e-09 8.62271153587147e-10 49.710086105566745 1.1128000000000181e-09 1.0316438425171488e-09 92.70703113921029 -4.0720000000001877e-10 1.0949100079847175e-09 -268.8875265188279 -2.8680000000000324e-10 1.081101066461029e-09 -376.95295204359024 1.881200000016489e-09 8.350006019189577e-10 44.386593765237016 1.52439999999998e-09 1.5170579860330034e-09 99.51836696621773 1.4096000000000395e-09 9.67685446322653e-10 68.64964857566869 +r_1710 D-galactose exchange 6.5999999999999985e-12 1.2553721328109792e-10 1902.0789891075444 -1.7999999999999986e-11 2.3682740011133013e-10 -1315.7077783962795 1.6e-12 6.927048202470825e-11 4329.405126544266 7.000000000000001e-12 1.1727638615744528e-10 1675.3769451063608 1.0000000000000002e-12 6.782270994289086e-11 6782.270994289085 3.7199999999999947e-11 2.6120835737241555e-10 702.1730036892902 2.5799999999999972e-11 2.0770890351094186e-10 805.0732694222562 2.6e-12 8.120688955859776e-11 3123.3419060999145 1.4e-12 5.829853980974579e-11 4164.181414981845 +r_1711 D-galacturonate exchange 1.2e-12 3.4623687844479196e-11 2885.3073203732665 4.799999999999999e-12 6.912246800510246e-11 1440.0514167729682 5.520000000000002e-11 2.2839306617875598e-10 413.7555546716592 4.5960000000001804e-10 4.984150113155646e-10 108.44538975534051 9.23399999999985e-10 2.659823101596455e-10 28.80466863327375 5.818000000000274e-10 4.933127116609755e-10 84.79077202835205 5.599999999999999e-12 7.463078420323923e-11 1332.6925750578437 3.0820000000000675e-10 4.617958543363034e-10 149.8364225620679 1.759999999999999e-11 1.31505508400778e-10 747.1903886407845 +r_1712 D-glucitol exchange 8.920000000000079e-11 6.63725444964449e-10 744.0868217090173 -9.957999999999599e-10 8.356887429749358e-11 -8.392134394205357 -9.775999999999663e-10 2.0274728430305567e-10 -20.739288492539146 -9.961999999999598e-10 8.358802181818645e-11 -8.390686791627164 -9.735999999999676e-10 2.1473765960467435e-10 -22.056045563340334 1.5399999999999997e-11 5.919737549801369e-10 3843.985421948941 -9.765999999999664e-10 1.9198909334227647e-10 -19.65892825540477 -9.155999999999875e-10 3.0609700925655687e-10 -33.43130288953265 -9.80199999999965e-10 1.903029244142255e-10 -19.41470357215184 +r_1713 D-glucosamine 6-phosphate uniport -9.192153645259462e-06 0.0003752242021263 -4082.005334188859 -2.481069649440992e-05 0.0006627111688963 -2671.0703951646065 -2.943582333517809e-05 0.0009304904010142 -3161.081619559124 -3.354505390423862e-05 0.0011856560022504 -3534.518101044615 -5.209005860471113e-05 0.0021261699311339 -4081.7192149245593 -1.56161565118214e-05 0.0008576368225609 -5491.984035326957 -1.3521652279311522e-05 0.0009561622012975 -7071.341442203023 -7.922362201792214e-05 0.0039605680096619 -4999.226125720398 -7.610658210769479e-05 0.0038049673386131 -4999.524657708267 +r_1714 D-glucose exchange -0.3730299323472312 0.0130783385715171 -3.505975643622952 -0.5695554465903355 0.0095599354388294 -1.6784907415178578 -1.3101497084455276 0.0435648664526648 -3.32518231861868 -1.8564468012284865 0.0091578215128263 -0.493298353972019 -2.705567237441184 0.1202915562676779 -4.446075285175498 -3.12800616457598 0.0481914659106803 -1.5406448509097812 -3.593461168459544 0.1337057040099515 -3.7208055894275582 -5.565805477028903 0.2416887387539248 -4.342385657411464 -7.6742181203995425 0.2734458369062847 -3.563175200603346 +r_1715 D-mannose exchange -8.593638406801562e-11 1.3389797153810355e-09 -1558.1057195998385 -1.7260818273328223e-10 4.5251461577684947e-10 -262.1628990069865 -2.600000000000001e-12 5.09289578898884e-11 -1958.8060726880149 -2.239999999999997e-11 1.4799533953508704e-10 -660.6934800673538 -3.200000000000001e-12 6.317086442041264e-11 -1974.0895131378943 -6.438250228634859e-11 2.7002958251915104e-10 -419.4145504288781 -2.800000000000001e-12 5.2846178137199376e-11 -1887.363504899977 -3.8e-12 6.153305829757655e-11 -1619.2910078309617 -5.599999999999999e-12 7.463078420323796e-11 -1332.692575057821 +r_1716 D-ribose exchange -4.728000000000192e-10 5.048872569479689e-10 -106.78664487054743 -6.096000000000292e-10 4.899345335546598e-10 -80.3698381815348 -5.952000000000282e-10 4.933412988261263e-10 -82.88664294793392 -5.546000000000254e-10 5.002688215137651e-10 -90.203537957761 -5.11000000000022e-10 5.043112788479063e-10 -98.69105261211048 -8.43000000000013e-10 3.6657587969628734e-10 -43.484683237993096 -7.092000000000367e-10 4.607361669796469e-10 -64.96561858144712 -6.192000000000302e-10 4.868662729677977e-10 -78.62827405810306 -8.344000000000161e-10 3.760384567889192e-10 -45.06692914536337 +r_1717 D-sorbitol transport -8.920000000000079e-11 6.63725444964449e-10 -744.0868217090173 9.957999999999599e-10 8.356887429749358e-11 8.392134394205357 9.775999999999663e-10 2.0274728430305567e-10 20.739288492539146 9.961999999999598e-10 8.358802181818645e-11 8.390686791627164 9.735999999999676e-10 2.1473765960467435e-10 22.056045563340334 -1.5399999999999997e-11 5.919737549801369e-10 -3843.985421948941 9.765999999999664e-10 1.9198909334227647e-10 19.65892825540477 9.155999999999875e-10 3.0609700925655687e-10 33.43130288953265 9.80199999999965e-10 1.903029244142255e-10 19.41470357215184 +r_1718 D-xylose exchange 1.240000000000001e-11 1.8829054853107157e-10 1518.4721655731566 2.800000000000001e-12 7.741678546500293e-11 2764.8851951786755 2.600000000000001e-12 5.092895788988538e-11 1958.806072687899 1.4e-12 4.240754272456608e-11 3029.110194611863 1.4e-12 3.7394112690807915e-11 2671.0080493434225 2.0799999999999976e-11 1.7312814523045018e-10 832.346852069473 2.259999999999997e-11 1.4863935794986484e-10 657.6962741144472 2.559999999999996e-11 1.7248359376480875e-10 673.7640381437853 1.6e-12 3.9971984588089866e-11 2498.2490367556165 +r_1719 D-xylose transport -1.240000000000001e-11 1.8829054853107157e-10 -1518.4721655731566 -2.800000000000001e-12 7.741678546500293e-11 -2764.8851951786755 -2.600000000000001e-12 5.092895788988538e-11 -1958.806072687899 -1.4e-12 4.240754272456608e-11 -3029.110194611863 -1.4e-12 3.7394112690807915e-11 -2671.0080493434225 -2.0799999999999976e-11 1.7312814523045018e-10 -832.346852069473 -2.259999999999997e-11 1.4863935794986484e-10 -657.6962741144472 -2.559999999999996e-11 1.7248359376480875e-10 -673.7640381437853 -1.6e-12 3.9971984588089866e-11 -2498.2490367556165 +r_1720 dADP transport -4.824964936922191e-10 9.659440096832028e-10 -200.1971044994517 -4.834000000000217e-10 7.93126881431938e-10 -164.07258614644235 -7.514000000000425e-10 6.62484578811806e-10 -88.16669933614166 -6.118000000000313e-10 6.905042499679987e-10 -112.86437560770896 -7.055233843900429e-10 6.834546742438216e-10 -96.87200869106547 -4.225000000000181e-10 7.892834368392311e-10 -186.8126477725911 -5.137000000000276e-10 8.703526944650295e-10 -169.42820604730056 -6.34900000000034e-10 6.937205775007094e-10 -109.26454205397266 -7.471229859675463e-10 6.50760611131047e-10 -87.10220718056114 +r_1721 dCDP transport -7.801830073661116e-10 5.111660177301745e-10 -65.51873251583173 -6.560296732760621e-10 5.560715045551345e-10 -84.76316349811448 -8.550055395166411e-10 4.2848850778911235e-10 -50.11529025079172 -7.422000000000394e-10 5.089115426001307e-10 -68.56797933173048 -8.188000000000213e-10 4.582669109943727e-10 -55.96811321377145 -6.002000000000286e-10 5.727351614079811e-10 -95.42405221725322 -7.63820960212141e-10 5.054526252871003e-10 -66.17422820482926 -8.070000000000252e-10 4.72224098410735e-10 -58.51599732474848 -8.39800000000014e-10 4.401984949349265e-10 -52.4170629834388 +r_1722 ATP deamination 8.85806439700855e-06 0.0004428582392005 4999.492206786228 1.0152995086505634e-11 7.179251675021993e-10 7071.067811865636 1.362494097274816e-05 0.0006811759970962 4999.478518539906 2.012734255457567e-05 0.0010062638848728 4999.487051727441 2.009222164828052e-05 0.0014207288847921 7071.039279091919 1.6416259572351393e-05 0.0011608045986681 7071.066301992451 9.060249799278252e-05 0.0036980915115974 4081.666172043168 4.583735430179951e-05 0.0032411904058452 7071.067811865498 4.4033272735039824e-05 0.0031136224252328 7071.067472019155 +r_1723 dATP deamination -5.492000000000247e-10 4.992286107998731e-10 -90.90105804804266 -6.086000000000292e-10 4.905651545250203e-10 -80.60551339549731 -8.480000000000068e-11 2.987085625841098e-10 -352.25066342465493 -1.7499999999999847e-10 3.841933379227022e-10 -219.53905024154605 -2.8200000000000476e-10 4.570752493372293e-10 -162.0834217507878 -2.1339999999999967e-10 4.165274769181576e-10 -195.18625909941807 -1.6986582746349655e-10 3.8531849332099157e-10 -226.83696837363885 -1.354090569060215e-10 3.53063026273733e-10 -260.7381177750693 -1.1300000000000039e-10 3.247338763019483e-10 -287.3751117716347 +r_1724 ADP deamination 3.163792532893179e-05 0.0010000784519223 3161.0114807615714 1.1518444637813836e-05 0.0008144762707087 7071.061209383758 1.9464302198432807e-05 0.000973109231398 4999.456037403556 4.313008404164636e-05 0.00176041855667 4081.648797554457 5.7406115598106e-05 0.0028700186875545 4999.499892393481 7.035536365274647e-05 0.0028716700702308 4081.664739030561 0.00017214135717 0.0060843477515881 3534.506670338811 0.0001964458162096 0.0080182620985686 4081.666005047967 0.0001887140965312 0.0077026789823301 4081.665929527629 +r_1725 dADP deamination 4.99430749085642e-10 6.238998163338651e-10 124.92218740558148 5.870000000000278e-10 5.367388729387171e-10 91.4376274171536 -1.6779999999999866e-10 5.728078052508895e-10 -341.3634119492814 1.1740000000000024e-10 4.72082421153827e-10 402.11449842745 2.1179999999999957e-10 5.63031225450376e-10 265.83155120414415 1.641999999999988e-10 4.94860927400326e-10 301.3769350793725 1.0600000000000059e-10 4.795935800241718e-10 452.4467736077068 7.680000000000049e-11 4.4423105277056045e-10 578.4258499616635 4.739999999999986e-11 4.3126608733777085e-10 909.8440661134432 +r_1726 deamino-NAD+ diffusion -7.66603975879346e-09 1.3478629487755171e-08 -175.82258782697133 -1.1836579193378575e-09 8.986969470796211e-09 -759.2539469362526 -7.180637362736061e-11 4.800421863243218e-10 -668.5230879580441 -1.0120000004507276e-10 4.67549227832572e-10 -462.0051656366933 -1.818834177268412e-10 5.769057590629344e-10 -317.1843625290523 -8.210219927298444e-11 4.0362778844568654e-10 -491.6162928883922 -1.1106932229963534e-10 5.140292433217514e-10 -462.80037788925927 -4.64782091662039e-11 5.688427149368846e-10 -1223.8912065280526 -6.859810487977699e-11 4.4829538801105407e-10 -653.5098728991469 +r_1727 decanoate exchange 9.366186212654776e-06 0.000171563910156 1831.737126090964 4.358186583139713e-06 0.0001231161791249 2824.9405291915846 3.4976278754929547e-06 0.0001192991622605 3410.859202503922 3.991193279511316e-06 0.0001456949038359 3650.409630220433 1.2383588829599773e-05 0.0003917808821791 3163.710355456349 5.097427912913444e-05 0.0007698514867298 1510.274396974866 2.651291781366068e-05 0.0007081983483097 2671.144508828356 2.2489423477085668e-05 0.00079564984919 3537.8845971786527 1.107151134962612e-05 0.0005535655800913 4999.9097919911965 +r_1728 deoxyadenosine transport 9.827999999999644e-10 1.3155843387752042e-10 13.386084033122222 9.747999999999671e-10 1.5674780373196202e-10 16.079996279438582 9.845999999999635e-10 1.2314979973444173e-10 12.507596966732304 9.805999999999652e-10 1.3794000684753963e-10 14.066898515964157 9.799999999999654e-10 1.4143550049460902e-10 14.432193928021842 9.80999999999965e-10 1.3653837755631535e-10 13.918285173936823 9.175999999999871e-10 2.7500066376833117e-10 29.969557952085346 9.721999999999682e-10 1.6562803666439628e-10 17.036416032133484 9.82999999999964e-10 1.2928396214757015e-10 13.15197987259154 +r_1729 deoxyadenylate kinase -6.406064689280044e-05 0.000885775678739 -1382.7142273809852 -8.48515673064905e-05 0.0019746106091626 -2327.135104093298 -0.0002685119092164 0.0016683710013929 -621.3396665575102 -0.0004001293364417 0.0024403536813752 -609.8912174440867 -0.0004877449639658 0.0056812308101939 -1164.795380766118 -0.0006701057755522 0.0040203509698667 -599.957665870499 -0.0006792794649378 0.0073962051809233 -1088.830969091634 -0.0007355319124973 0.0112256001722413 -1526.1880526878888 -0.0008816451332929 0.0107837786375453 -1223.1427623569473 +r_1730 deoxycytidine exchange -6.303254747108172e-10 1.0408219330359084e-09 -165.1245229321281 -7.41240170289834e-10 4.658141839687348e-10 -62.84254451382413 -6.571722242465314e-10 6.99442609481504e-10 -106.43216247969652 -7.174820558870823e-10 4.6722850125785e-10 -65.12058349392123 -6.904922329729401e-10 6.009177755765743e-10 -87.02744895323448 -6.61116370839584e-10 1.0419243632648443e-09 -157.60075067293428 -6.347885529871525e-10 6.21201622755334e-10 -97.85961322587158 -6.911351526691351e-10 6.42239237411055e-10 -92.92527444606948 -8.02105255129495e-10 5.87788879249974e-10 -73.28076651923683 +r_1731 deoxycytidine transport 6.303254747108172e-10 1.0408219330359084e-09 165.1245229321281 7.41240170289834e-10 4.658141839687348e-10 62.84254451382413 6.571722242465314e-10 6.99442609481504e-10 106.43216247969652 7.174820558870823e-10 4.6722850125785e-10 65.12058349392123 6.904922329729401e-10 6.009177755765743e-10 87.02744895323448 6.61116370839584e-10 1.0419243632648443e-09 157.60075067293428 6.347885529871525e-10 6.21201622755334e-10 97.85961322587158 6.911351526691351e-10 6.42239237411055e-10 92.92527444606948 8.02105255129495e-10 5.87788879249974e-10 73.28076651923683 +r_1732 deoxyguanosine transport 1.3609033257663262e-10 3.527356589957199e-10 259.19229699662463 1.1840000000000018e-10 3.261942987608861e-10 275.5019415210182 1.94198317655269e-10 7.684054766605895e-10 395.68081018323966 5.819088602385657e-11 3.135109013346032e-10 538.7628935673414 1.4639999999999936e-10 3.5635998440859407e-10 243.41528989658173 1.4099999999999951e-10 3.5205651358516883e-10 249.6854706277802 1.8139999999999828e-10 3.9054390906655767e-10 215.29432693856748 2.2580000000000055e-10 4.22906762804749e-10 187.292631888728 1.7979999999999828e-10 3.88203684191809e-10 215.9086118975599 +r_1733 deoxyinosine transport -9.505999999999756e-10 2.3102015942945523e-10 -24.302562532028315 -8.34200000000016e-10 3.8566839126585536e-10 -46.23212554133876 -9.34599999999981e-10 2.667153302933255e-10 -28.53791250731124 -9.43599999999978e-10 2.3922894076015225e-10 -25.352791517608924 -9.615999999999715e-10 1.9832626316584622e-10 -20.62461139411939 -9.445999999999775e-10 2.398798625764344e-10 -25.394861589714168 -8.384000000000145e-10 3.968840427488816e-10 -47.3382684576425 -8.006000000000275e-10 4.148180984611757e-10 -51.813402255953214 -9.45799999999977e-10 2.3931948262301616e-10 -25.30339211493149 +r_1734 deoxyuridine kinase (ATP:deoxyuridine) 0.0001476077669738 0.003297629479715 2234.0487545612127 0.0002418591632573 0.0056960767108022 2355.121316922076 0.0001361806460644 0.003929218761238 2885.298957518054 0.000167626391215 0.0052986619476749 3160.995061260171 0.0003347257734931 0.0105807066522116 3161.007454488568 0.000273435255358 0.0086432685903396 3160.9927472670784 0.0005033285267452 0.0159048335951497 3159.9308900687506 0.0014644786345964 0.0329858183729634 2252.3932813846586 0.000880640752384 0.0254025723932872 2884.5556289005617 +r_1735 deoxyuridine transport 1.6500427027420807e-11 6.492443896220867e-10 3934.7126504250873 4.30602241850506e-10 7.034836390738195e-10 163.3720335617879 -1.2454966873886788e-10 6.099390169836936e-10 -489.71548713027727 3.899634565115882e-10 6.562483650811109e-10 168.28458003515763 -2.1734842171259027e-12 6.797265443288296e-10 -31273.59007132166 -4.095691966525945e-11 5.207891318199391e-10 -1271.5534666091692 2.6467131001687143e-11 6.650219535342434e-10 2512.6333242989263 7.807712124316017e-12 5.751507435600266e-10 7366.444028703374 6.401793811997416e-11 6.260945800408192e-10 977.9986647921608 +r_1736 dephospho-CoA kinase 3.967140312076874e-05 0.0008848860573219 2230.538845899128 0.0001556850481813 0.0020118262970998 1292.2411757593754 4.981609505464596e-05 0.0010656519255735 2139.171937111028 0.0001098301739132 0.0017981209183906 1637.1829838045194 0.0002003831856752 0.0040195740520383 2005.9437814074545 0.0001690922225225 0.0031881480188338 1885.4492366781008 0.0003941303398992 0.007104097696264 1802.474201321124 0.0006587538877613 0.0115723108151397 1756.6971565763972 0.0005519866210736 0.010321042291261 1869.7993569456623 +r_1737 dGDP transport -7.329688461486148e-10 5.713667096643737e-10 -77.95238674421438 -5.958000000000296e-10 6.673165832530015e-10 -112.00345472523804 -8.798000000000001e-10 4.061834031461663e-10 -46.16769756151014 -7.646000000000406e-10 4.854214321528787e-10 -63.4869777861435 -7.697997971161679e-10 5.685670257878032e-10 -73.85907711560527 -6.210000000000307e-10 6.097814089272654e-10 -98.19346359536794 -8.04800000000026e-10 4.634003754655306e-10 -57.579569516092896 -8.128000000000236e-10 4.662613429483214e-10 -57.36483057927014 -8.216460393445852e-10 4.821147130418901e-10 -58.67669165988628 +r_1738 dhnpt transport 1.4369957721759477e-06 2.1435157551801863e-09 0.1491664621903794 2.3423345049184554e-06 2.3253499579600802e-09 0.0992748880690306 5.444508710494739e-06 2.4191601629719702e-09 0.0444330295276934 8.098384123096459e-06 2.16857887375443e-08 0.2677792064184358 1.1419280920420364e-05 4.782435801770128e-08 0.4188035862414073 1.3534823348019532e-05 3.9170773797414833e-08 0.2894073516160552 1.5152890059326289e-05 7.131036662460118e-08 0.4706057151171049 1.7795862689727744e-05 1.0419694994183641e-07 0.585512215724061 2.0178464727001844e-05 1.0145823451234785e-07 0.5028045289123573 +r_1739 diamine transaminase 2.642000000000035e-10 4.409503911433593e-10 166.9002237484306 2.1659999999999998e-10 4.1196891105606757e-10 190.1980198781476 1.6839999999999866e-10 3.7425853883483666e-10 222.2437879066744 2.43800000000002e-10 4.294163942933967e-10 176.1346982335493 8.420000000000068e-11 2.777152951441893e-10 329.8281415014099 2.3680000000000145e-10 4.2516104287961655e-10 179.54435932416132 1.1080000000000043e-10 3.13915703037819e-10 283.317421514276 1.0380000000000068e-10 3.0568652055622655e-10 294.49568454356904 3.850000000000126e-10 4.86643981235644e-10 126.40103408717611 +r_1743 dihydrofolate transport -3.198799980355534e-09 1.0273436443459306e-08 -321.1653278276391 -3.856674407772748e-09 1.4162270313528021e-08 -367.2145692409335 -4.254584909514249e-09 1.5382354730010007e-08 -361.54771986361015 -5.49559178210821e-10 1.4420069695000612e-09 -262.3933921356292 -1.063720794972362e-09 6.503436117565667e-10 -61.13856331759165 -1.1202902938101204e-09 1.0937404311784284e-09 -97.63009080964228 -1.1839465082034355e-09 1.0614551350527608e-09 -89.65397741351106 -1.0768981972474055e-09 9.235344239111163e-10 -85.75874918090744 -6.816678994748685e-10 1.0700226383232178e-09 -156.97125229859338 +r_1744 dihydroneopterin triphosphate pyrophosphatase 1.43380759784012e-06 7.895899200150095e-08 5.506944733759561 2.3458527769333342e-06 1.5414835985259413e-07 6.571101194769257 5.448073555202645e-06 4.735694502679962e-07 8.692420274240982 8.037755359663406e-06 6.96556864883725e-07 8.6660620249693 1.1324512920301832e-05 1.0323713787825087e-06 9.116254147511652 1.342666012061384e-05 1.206555098353531e-06 8.98626380287319 1.507116648288732e-05 1.1129104338045136e-06 7.384368257547794 1.76144637795849e-05 1.7913246813252788e-06 10.169623689603412 1.993618772933048e-05 2.199786318220265e-06 11.034137258769384 +r_1745 dihydropteroate transport -1.436987612887239e-06 2.082713003827638e-09 -0.1449360443436939 -2.3423895575549425e-06 3.114112384134228e-09 -0.132945964265006 -5.444509710427241e-06 2.69462077219658e-09 -0.0494924412943168 -8.098203956458648e-06 2.1818684485512966e-08 -0.2694262160205494 -1.1419221627312463e-05 4.784198087383005e-08 -0.4189600870816073 -1.353479041096314e-05 3.91790483952046e-08 -0.2894691916578899 -1.5152735033287662e-05 7.134676317054496e-08 -0.4708507276990573 -1.7795814718847523e-05 1.0420894465519297e-07 -0.5855811959248228 -2.017776524370258e-05 1.0162029527803584e-07 -0.5036251242428902 +r_1746 dihydroxyacetone phosphate transport 0.0025454018415529 0.0670169146590203 2632.86187528385 0.004643054331472 0.1210591963474629 2607.318107972297 0.0117621238423593 0.2481322030169772 2109.586723814023 0.018004928283638 0.3928780318755187 2182.058299185489 0.0221790454853248 0.516505929861253 2328.801436486558 0.0204997090350346 0.5067542598743149 2472.0070856042626 0.059022792151849 0.7590398990341971 1286.0115073536358 0.0204590830096079 0.5089984758653544 2487.885090579671 0.0440100184142579 0.9212072453853598 2093.176232543716 +r_1747 diphosphate transport -0.0005158081973744 0.0042495822147629 -823.8686853744687 -0.0008953689516506 0.0072780584976766 -812.8558047784989 -0.0007369847026955 0.0061031249812851 -828.1209852745304 -0.0010925491567935 0.0089385932954576 -818.1410639399761 -0.0018838787298401 0.0159590445281986 -847.1375718304566 -0.0017164763447519 0.0145811537205021 -849.481774979488 -0.003204565529963 0.0268564918250425 -838.0696719705568 -0.0049347911830206 0.0407035023356624 -824.8272485310604 -0.0044640691716884 0.0378571015448832 -848.0402092551996 +r_1748 dolichol phosphate transport -0.0210693032639376 0.0001556719111275 -0.7388564736925628 -0.0334436119823008 0.0002063273361276 -0.616940945962407 -0.0683715719418947 0.0001926406858326 -0.2817555313725706 -0.0903990446793599 0.0002447409761445 -0.2707340293391953 -0.1601433339189001 0.0006742763447699 -0.4210455273220242 -0.1671155370820592 0.0004867447182323 -0.2912623965019507 -0.1813989425947403 0.0008570502740961 -0.4724670727606674 -0.1986324404306186 0.0011660469787323 -0.5870375333477377 -0.2415558085197562 0.0012161449605629 -0.5034633478761753 +r_1749 dTTP exchange 2.7113525910357385e-06 0.0001106875116519 4082.3724667138463 4.252074463133934e-06 0.0001735800040542 4082.242810167388 1.227290774545918e-05 0.0003279444269337 2672.1004812824613 7.710828981426133e-06 0.000314761921963 4082.076294536592 1.5684586001669906e-05 0.0006402221988453 4081.8558983782814 2.145553782477275e-05 0.0005854482518552 2728.6580119154464 -8.162943651113845e-10 1.3283246447772855e-09 -162.72618084237703 7.1243005225939e-05 0.0020556451283666 2885.3992358231244 3.437468910179376e-05 0.0014030902123679 4081.7538980876193 +r_1750 dTTP uniport -2.7113525910357385e-06 0.0001106875116519 -4082.3724667138463 -4.252074463133934e-06 0.0001735800040542 -4082.2428101673886 -1.227290774545918e-05 0.0003279444269337 -2672.1004812824613 -7.710828981426133e-06 0.000314761921963 -4082.07629453659 -1.5684586001669906e-05 0.0006402221988453 -4081.855898378284 -2.1455537824772755e-05 0.0005854482518552 -2728.6580119154464 8.162943651113845e-10 1.3283246447772855e-09 162.72618084237703 -7.1243005225939e-05 0.0020556451283666 -2885.3992358231244 -3.437468910179376e-05 0.0014030902123679 -4081.7538980876193 +r_1751 dUDP diffusion -5.314090423627278e-05 0.001533276364638 -2885.303490171884 -8.048468685587742e-05 0.0025441526601229 -3161.0393970703617 -2.7249918809775475e-05 0.0013623530885052 -4999.475770975501 -0.0001006361326835 0.0031811321492714 -3161.0238434683024 -0.0003214746384933 0.0080312309176375 -2498.2471262051854 -0.0001313288043868 0.0046418224151145 -3534.504434717611 -0.0002413364609305 0.0085300059553376 -3534.487048681549 -0.0002750238411153 0.0112255666766018 -4081.670385765724 -0.0001761332279664 0.0088057761472108 -4999.49739687305 +r_1752 dUMP transport 5.314040967390357e-05 0.0015332763586724 2885.330331627918 8.048452598773619e-05 0.0025441526652695 3161.045721580372 2.724955122904424e-05 0.0013623530758522 4999.543164586656 0.0001006362860382 0.0031811321254337 3161.0190028537263 0.000321474172637 0.0080312309012571 2498.2507413821563 0.0001313295625448 0.0046418224502563 3534.4840569856246 0.0002413368718158 0.008530005957875 3534.4810321340246 0.000275023835074 0.0112255666849184 4081.670478450673 0.0001761327200976 0.008805776147368 4999.51181273173 +r_1753 episterol exchange 2.408069650141304e-07 1.7087017677809992e-05 7095.732333492654 2.598221439631906e-07 1.8432461436690137e-05 7094.261157086554 1.205559987605323e-06 3.979115286485135e-05 3300.6364904239176 1.3566034285824889e-06 4.989759166357433e-05 3678.126607398611 9.324591029494442e-07 6.598903534383355e-05 7076.882528692664 7.271036085783677e-06 0.0001818781783152 2501.406624439857 5.622901188844505e-06 0.0001987630146351 3534.8836474223986 4.152187066949798e-06 0.0002077124743812 5002.483535352981 7.938936521309542e-06 0.0002807717593043 3536.6419488398096 +r_1754 ergosta-5,6,22,24,(28)-tetraen-3beta-ol transport 0.0008398668803714 4.839332147879687e-05 5.762022840737752 0.0013685772518619 6.842335384850992e-05 4.9995974838409785 0.0031749275688206 8.756256768669549e-05 2.757939064393212 0.0047196905617361 0.0001303944125048 2.762774609887368 0.0066561144929401 0.0002330114516317 3.500712793911908 0.0078839868969702 0.0001928268149889 2.4458033417468217 0.0088298845839995 0.0003035071160198 3.437271610206653 0.010376551751775 0.000482226161875 4.647267930722303 0.0117597368091258 0.0004446597166924 3.781204663928735 +r_1757 ergosterol exchange 1.9230642693779018e-06 4.7819943390544114e-05 2486.653418297535 3.5943938381501626e-06 6.733723263032255e-05 1873.396062379668 4.862111921182241e-06 8.584205595311377e-05 1765.5302334595572 7.425116498951664e-06 0.0001271579240667 1712.5377640157833 1.169691348599684e-05 0.00022914472454 1959.0187173251395 8.403767049902035e-06 0.0001882747060467 2240.360839713793 1.3336902780067178e-05 0.0002983187850831 2236.7920798595965 2.230809541754913e-05 0.0004748289075747 2128.504915759114 1.9554100894056804e-05 0.0004369970260079 2234.810121802993 +r_1758 ergosterol transport 0.0006075800815317 7.025641864938294e-05 11.56331828262971 0.0009828403951317 0.0001199127215013 12.200630142522655 0.0022800077983492 0.0001901372863038 8.339326139212762 0.0033766213672668 0.0003911913566936 11.585289380854752 0.0047929985524726 0.0003691392393217 7.701634692365331 0.0056634394421576 0.0004725957524818 8.344677422768019 0.0061899384950285 0.0011000973107916 17.772346392055418 0.0074532574774845 0.0007216584704355 9.68245726939704 0.0084370687057216 0.0008168677380783 9.6818903172419 +r_1759 ergosterol transport -8.791709184521833e-05 0.0019613620664367 -2230.9223670521965 -0.0002422532737202 0.0044060087919305 -1818.7613006289705 -0.0001547461552506 0.0031399118652286 -2029.072619053121 -0.0002854810112805 0.00530957174628 -1859.8686204954083 -0.00056596268894 0.0106183789943498 -1876.162369331384 -0.0005631795987629 0.0095579841100475 -1697.1467238944176 -0.0007956199481867 0.015376328975326 -1932.6223544759275 -0.0013809875607127 0.0250430042738335 -1813.412733486796 -0.0015957089912446 0.0263759727195886 -1652.9312590395982 +r_1761 ethanol exchange 0.0078751282176829 0.004041392422257 51.31843330731286 6.219857380557045e-06 0.0002116676553452 3403.0949971121254 0.0001258161927579 0.0011107482409781 882.834090453758 2.361615779980797e-05 0.0004821605977646 2041.655555708488 8.986929937551928e-05 0.0009431282825614 1049.4443476415966 0.0074383208536441 0.0042956681756449 57.75050929055271 0.0001018988166621 0.0010031169829705 984.4245652988388 1.8494338136989383 0.0599085951612742 3.2392938161682463 4.903095644615362 0.0525343006846679 1.0714516805798346 +r_1762 ethanol transport 0.0078751282176829 0.004041392422257 51.31843330731286 6.219857380557045e-06 0.0002116676553452 3403.0949971121254 0.0001258161927579 0.0011107482409781 882.8340904537578 2.361615779980797e-05 0.0004821605977646 2041.655555708488 8.986929937551928e-05 0.0009431282825614 1049.4443476415966 0.0074383208536441 0.0042956681756449 57.75050929055271 0.0001018988166621 0.0010031169829705 984.4245652988388 1.8494338136989383 0.0599085951612742 3.2392938161682454 4.903095644615362 0.0525343006846679 1.0714516805798346 +r_1763 ethanol transport, mitochondrial 0.0002171405847837 0.0065754333131925 3028.1917679005714 -0.008779060819266 0.1625359581506625 -1851.4048540815509 -0.0013717994454998 0.0208849991883371 -1522.45280874328 -0.0002225702342543 0.0107726511262305 -4840.113127580723 -0.0340403731070912 0.6100858600451758 -1792.2419890223905 -0.0020738119102229 0.0478878008876484 -2309.167994049217 9.602263911934426e-05 0.0335724145907426 34963.02007385601 -0.0078170180466219 0.1731427278798367 -2214.9459915173097 -5.653523650666695 0.236843864228809 -4.189314113877972 +r_1764 ethanolamine exchange 4.756000000000192e-10 5.167765973903231e-10 108.65782115018968 3.722000000000116e-10 5.088407843213442e-10 136.71165618520374 3.0920000000000675e-10 4.968347098842593e-10 160.68392945803632 2.5440000000000276e-10 4.566424689720627e-10 179.49782585379631 3.6500000000001104e-10 5.12471975336316e-10 140.403280914055 4.2420000000001555e-10 5.19141851185524e-10 122.38138877546088 3.030000000000064e-10 4.712063317501224e-10 155.51364084162137 1.875999999999981e-10 4.015451253564545e-10 214.04324379342145 1.7559999999999844e-10 3.9597474565916485e-10 225.49814673073368 +r_1765 ethyl acetate exchange 0.0004089814647661 0.0047101455876273 1151.677030234151 2.7390540629527444e-05 0.0008632934510817 3151.7941276086726 0.0002372391297508 0.0046348449640506 1953.659570795865 8.473849746521048e-05 0.0020528617523585 2422.5845557402235 0.0007482768672045 0.0123634461975153 1652.25556734136 0.0014183922922463 0.0173771231774675 1225.1281449046023 0.0009566635988363 0.0168169615245565 1757.876179778522 0.0017944536552607 0.0326922013723234 1821.847071752452 0.0012119925667599 0.0255913945349434 2111.514149245799 +r_1766 farnesyl diphosphate transport 1.3958301013697196e-05 0.0001439642894916 1031.388342681446 8.005891317926721e-06 0.0001060046000509 1324.082426820108 1.442112067883581e-05 0.0001678546714673 1163.9502588293217 1.3929719867077416e-05 0.0002030935302796 1457.987182927427 4.5321993977749794e-05 0.000513016162131 1131.9364332975897 3.8587116727232353e-05 0.0004661301435597 1207.9942299259296 4.060587165422494e-05 0.0005824694663705 1434.4464055113838 9.34688555710928e-05 0.0011187945380192 1196.9704038670634 9.266253253933534e-05 0.0010814233637298 1167.0556956456646 +r_1770 fatty acid transport -9.366186212654776e-06 0.000171563910156 -1831.737126090964 -4.358186583139713e-06 0.0001231161791249 -2824.9405291915846 -3.4976278754929547e-06 0.0001192991622605 -3410.859202503922 -3.991193279511316e-06 0.0001456949038359 -3650.409630220434 -1.2383588829599773e-05 0.0003917808821791 -3163.710355456349 -5.097427912913444e-05 0.0007698514867298 -1510.274396974866 -2.651291781366068e-05 0.0007081983483097 -2671.144508828356 -2.2489423477085668e-05 0.00079564984919 -3537.8845971786527 -1.107151134962612e-05 0.0005535655800913 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1.1608772119585943e-09 152.2841067185658 -8.393141298147162e-07 5.940868876155168e-05 -7078.2424185646105 -3.601985848850564e-06 0.0001470555477004 -4082.624248715471 -2.4770740460601745e-06 0.0001752175636588 -7073.569881268835 -1.785757505591242e-05 0.0004769818930159 -2671.033953504253 -3.7237837128202417e-06 0.0002633723401564 -7072.707774345829 -5.652831169901754e-05 0.001262888792145 -2234.08192140825 -1.628904035524443e-05 0.0006648992938749 -4081.881310220375 +r_1788 fecosterol exchange 7.349290436062684e-07 3.0039750853656453e-05 4087.43553068097 1.0082409905577534e-06 3.5673469989163475e-05 3538.188818273408 9.50619066941167e-07 3.883262776836047e-05 4084.983051445968 9.1418656043508e-07 4.574794145297584e-05 5004.223802109217 4.675792342998824e-06 0.000147827519526 3161.5501434194825 -7.66395430107124e-10 1.3188946692162039e-09 -172.0906228566438 4.3080121256668656e-06 0.0001687885710635 3918.015226974463 2.133000786210125e-06 0.0001508813913353 7073.667872546798 2.049013195133396e-06 0.0001449432064821 7073.805421379714 +r_1790 FMN adenylyltransferase 2.2870293558508564e-09 2.7138665094984066e-08 1186.6338761920915 2.5505536745055867e-09 3.3929727079591433e-08 1330.2886905984658 7.962613812441204e-09 9.016050134330176e-08 1132.2978040506032 9.879011066214366e-09 1.196670738142595e-07 1211.3264476797058 1.8198540304492025e-08 1.969041144720839e-07 1081.9775167543585 1.9886161696548093e-08 2.2012818640915525e-07 1106.9415494462455 1.623457439917256e-08 2.336858162069106e-07 1439.4329685588864 2.6474605540837184e-08 3.2199375591790065e-07 1216.236273742489 3.537717222039045e-08 3.719359119516372e-07 1051.344380027252 +r_1791 FMN exchange -6.992992000000396e-10 4.779900883745159e-10 -68.35272918580326 -4.89298200000034e-10 5.191213448423111e-10 -106.09508574572216 -6.259998000000318e-10 5.489846331414393e-10 -87.69725375973144 -6.606998000000354e-10 5.039602858101918e-10 -76.27674260082486 -2.5800000000000304e-10 5.584786295606229e-10 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2.2480393659937348e-10 8.637246568454387e-10 384.2124252408868 2.8891337527430837e-10 2.389951334584833e-09 827.220730890599 3.4989483335762157e-10 8.03728989917183e-10 229.70587539247984 4.037252663412423e-10 8.690696583760181e-10 215.2626379448472 3.0580000000000664e-10 7.32662076774644e-10 239.5886451192375 -8.603012622367846e-11 9.307779192745571e-10 -1081.9209039104894 -2.0843324136044558e-10 9.242586925528735e-10 -443.43152105692417 2.1031198125100358e-10 8.945568974338024e-10 425.347567985756 +r_1795 formate transport -0.000291888298299 0.0016417990177142 -562.4751068411446 -0.0031046807860913 0.0028616155444477 -92.17100699264952 -0.0095526048630165 0.00206573445605 -21.62482888879548 -0.0091701552162207 0.0027260787724554 -29.727727701199548 -0.0096280235508419 0.0018804738920023 -19.531255631774 -0.0006069806392602 0.0023362032379971 -384.88925130205104 -0.0095978863510293 0.0019629285511747 -20.45167528957225 -0.0083237631272844 0.0037331694899169 -44.849540199913314 -0.0096069164712616 0.0019388916218813 -20.182247110000286 +r_1796 formate transport -2.030075150615569e-05 0.0007175332428952 -3534.515668928134 -5.317621010968256e-05 0.0016808632502022 -3160.930887581589 -0.0001190523440532 0.0034574281385689 -2904.124371564248 -0.0001004508989164 0.0041382538912921 -4119.678306447713 -0.0007751408943393 0.0173311321814479 -2235.868641173804 -7.52409615919303e-05 0.0026593768536312 -3534.4801519873627 -0.0006873022090514 0.0159044455264449 -2314.0396345292693 -0.0005105281263321 0.0150153603632932 -2941.142630312821 -0.0010966945247541 0.0316583713179296 -2886.7082495032632 +r_1797 fructose-1-phosphate kinase 2.1359999999999955e-10 4.3268057790533694e-10 202.56581362609447 3.0423333333333975e-10 4.852436433275624e-10 159.4971984203633 3.640370724023177e-10 7.476053254932635e-10 205.36516255329164 2.1226666666666627e-10 4.3802982219952573e-10 206.358270508571 2.0853333333333255e-10 4.226564390505305e-10 202.6805174475057 1.4849999999999923e-10 3.7205568815301585e-10 250.5425509447931 2.334000000000012e-10 4.342374378499402e-10 186.0486023350206 2.1866666666666666e-10 4.159026802658776e-10 190.1993964630538 1.6429999999999875e-10 3.7694021646060277e-10 229.42192115678972 +r_1798 fumarate exchange 2.030075150615569e-05 0.0007175332428952 3534.515668928134 5.317621010968256e-05 0.0016808632502022 3160.930887581589 0.0001190523440532 0.0034574281385689 2904.124371564248 0.0001004508989164 0.0041382538912921 4119.678306447713 0.0007751408943393 0.0173311321814479 2235.868641173804 7.524096159193031e-05 0.0026593768536312 3534.480151987362 0.0006873022090514 0.0159044455264449 2314.0396345292693 0.0005105281263321 0.0150153603632932 2941.142630312821 0.0010966945247541 0.0316583713179296 2886.708249503264 +r_1800 gamma-aminobutyrate exchange -1.0900000000000048e-10 3.1739430969940484e-10 -291.1874400911957 -3.294000000000084e-10 4.70042368266525e-10 -142.6965295283889 -3.8380000000001247e-10 4.896381409794494e-10 -127.57637857723653 -2.650000000000036e-10 4.413773473939748e-10 -166.55748958262978 -3.339999999999992e-11 1.7969668383038655e-10 -538.0140234442725 -6.920000000000034e-11 2.7789711290523387e-10 -401.5854232734575 -1.2320000000000008e-10 3.3293231862611086e-10 -270.2372716121028 -1.8699999999999806e-10 3.9504710154927677e-10 -211.255134518332 -8.946799709223912e-11 3.1782833547208356e-10 -355.2424842420593 +r_1801 GDP transport -0.0002037693402724 0.0038487198565785 -1888.7629765262843 -0.0002146100121896 0.0053615214135697 -2498.2624803318404 -0.0001580283946911 0.0042211809001339 -2671.153439471583 -0.0003006242291755 0.0070804108081455 -2355.2362454496947 -0.0004018424273879 0.0115944043161933 -2885.311138387881 -0.0004377502374026 0.0109361562315092 -2498.263917890022 -0.0009026863138794 0.0212606081884449 -2355.259835177254 -0.0012195615853178 0.0304682462618427 -2498.2950126214128 -0.0008806633592731 0.0254099045373824 -2885.314152090417 +r_1802 GDP transport 5.81800000000028e-10 6.227249129940671e-10 107.03418923926388 5.430000000000257e-10 6.996062390930576e-10 128.8409280097651 7.734000000000376e-10 5.842265863009265e-10 75.54002926052475 5.674000000000266e-10 7.056605638451696e-10 124.3673887636829 6.30199797116161e-10 7.396980350873053e-10 117.37516236473192 1.4421302904324595e-10 8.717432892998998e-10 604.4830311680684 3.42632843214656e-10 8.649482095468903e-10 252.441710325186 2.330000000000012e-10 9.062423820650972e-10 388.94522835411686 3.1260000000000743e-10 8.918746145426464e-10 285.30857790870937 +r_1803 GDP-alpha-D-mannose transport -0.0002037694939367 0.0038487198484411 -1888.7615482011047 -0.0002146102644173 0.0053615214034715 -2498.259539462613 -0.000158029347569 0.0042211808440394 -2671.1372975803984 -0.0003006244538814 0.0070804108464109 -2355.234497724266 -0.0004018436847582 0.011594404339026 -2885.3021159213386 -0.0004377549242721 0.0109361562400689 -2498.2371719180305 -0.0009026873354409 0.0212606081627658 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-6.186722205872087e-10 6.082651353105396e-10 -98.3178353689792 -7.80958499561942e-10 8.917763024614402e-10 -114.18997334194565 -8.16789838573192e-10 3.8810519663058445e-10 -47.51591882050656 -8.388858418715501e-10 3.831050095322852e-10 -45.66831270838711 -8.647790918802036e-10 3.8687160496385804e-10 -44.73646606357252 +r_1807 glutathione exchange -5.436281655976648e-10 8.01574897276678e-10 -147.4491109921479 -3.0590376690139904e-10 7.305354936995283e-10 -238.81219283416 -1.7697799979999843e-10 1.267208876586041e-09 -716.0262168281395 -6.396000000000317e-10 4.805809313802606e-10 -75.1377316104185 -3.8320000000001244e-10 4.874477213570716e-10 -127.20452018712312 -3.3660000000000885e-10 4.72594021356387e-10 -140.4022642175801 -3.605695611917271e-10 4.961109464917261e-10 -137.5909116820671 -5.017928856696611e-10 5.008535951998196e-10 -99.8128131153976 -5.787774493943167e-10 4.946377095581047e-10 -85.46250550634562 +r_1808 glycerol exchange 4.800263835610289e-05 0.0006912244454389 1439.9717788660134 8.000403010055711e-06 0.000282757818717 3534.2946894252746 1.8876219961960325e-05 0.0004278367204412 2266.538116759725 1.5999236614622637e-05 0.0003996974102009 2498.2280081764425 1.800014037372209e-05 0.0004239244476744 2355.1174539355657 3.2991399022009055e-05 0.0005667767665394 1717.953113056257 3.400035109379489e-05 0.0005821612478863 1712.2212834813 8.000409468846963e-06 0.0002827578183693 3534.291831816256 1.2000196562620244e-05 0.0003462368716346 2885.2600024333774 +r_1809 glycerol-3-phosphate shuttle 0.0025453974111833 0.0670169147723249 2632.866462340301 0.0046430498160118 0.121059196156682 2607.320639533143 0.0117621200522313 0.2481322030373828 2109.5874037632457 0.0180049249489877 0.3928780319821802 2182.058703911832 0.0221790401094863 0.5165059299229232 2328.8020012281995 0.0204997027059805 0.5067542601613634 2472.0078502090814 0.059022786740398 0.7590398995463414 1286.011626128147 0.0204590778818852 0.5089984764255738 2487.8857168643367 0.0440100154093668 0.921207245517676 2093.1763757610734 +r_1810 L-glycine exchange 0.0043641519566217 0.0070881905331765 162.41850887940947 0.0084107485605752 0.0067402003776268 80.13793693965567 0.1681960865576378 0.0779158027053819 46.32438500801955 0.0279408145651321 0.0475238637688323 170.08761021641158 0.6310941597215701 0.3014952650199896 47.77342023779861 0.0296659494788009 0.0312503023706935 105.340644475326 0.5534611574205959 0.2663579552815437 48.12586244044736 0.4351562834510379 0.2358245312795252 54.19306585884546 1.4780605885421418 0.696561506928685 47.12672216067447 +r_1811 glycine transport 0.0001073516127009 0.0011517154874089 1072.8441412584275 5.701697272885016e-05 0.0008480374842284 1487.3421783744218 9.9030410444859e-05 0.0013428395658191 1355.987074866128 8.717255587875309e-05 0.0016247489508768 1863.8308060356744 0.0003283584399656 0.0041041319748998 1249.8938584704997 0.0002681398225859 0.0037290428860534 1390.7083439118387 0.0002794405306779 0.0046597578670042 1667.531140060458 0.0006944240193706 0.0089503617242957 1288.889997268128 0.0006808329059011 0.0086513927282751 1270.707196037176 +r_1812 glycoaldehyde transport -1.4387585958703104e-06 1.076338428472802e-08 -0.7481021705533031 -2.3440709011700384e-06 1.1588955762907178e-08 -0.4943944211381393 -5.447877068414605e-06 1.6166419553629508e-08 -0.2967471429808551 -8.098340451280882e-06 2.170236760743649e-08 -0.2679853698173916 -1.1419215491986495e-05 4.783953822534133e-08 -0.4189389214952027 -1.3534791396601183e-05 3.917880482567012e-08 -0.2894673709970039 -1.5152735222525703e-05 7.13467172700775e-08 -0.4708504189000487 -1.7795814718847523e-05 1.0420894465519297e-07 -0.5855811959248227 -2.017821210077644e-05 1.0152161063331637e-07 -0.5031249058453989 +r_1813 glycoaldehyde transport -1.4530988815689713e-06 2.6115428477028776e-08 -1.7972230801547973 -2.3451588674730365e-06 1.3334761629411002e-08 -0.5686080296888167 -5.548274941775938e-06 1.0899840350272516e-08 -0.1964545820936481 -8.251435130172968e-06 2.1779640079220128e-08 -0.2639497219044802 -1.1634622602380386e-05 4.781342234350869e-08 -0.4109580858576908 -1.3793422289128807e-05 3.846197568218389e-08 -0.2788428779745069 -1.5439229236464032e-05 7.120092123860273e-08 -0.4611688844572756 -1.813331644943072e-05 1.0389470898730345e-07 -0.5729492962693271 -2.055993954035078e-05 1.013746229716122e-07 -0.4930686822918673 +r_1814 glycolaldehyde exchange 1.4530988815689713e-06 2.6115428477028776e-08 1.7972230801547973 2.3451588674730365e-06 1.3334761629411002e-08 0.5686080296888167 5.548274941775938e-06 1.0899840350272516e-08 0.1964545820936481 8.251435130172968e-06 2.1779640079220128e-08 0.2639497219044802 1.1634622602380386e-05 4.781342234350869e-08 0.4109580858576908 1.3793422289128807e-05 3.846197568218389e-08 0.2788428779745069 1.5439229236464032e-05 7.120092123860273e-08 0.4611688844572756 1.813331644943072e-05 1.0389470898730345e-07 0.5729492962693271 2.055993954035078e-05 1.013746229716122e-07 0.4930686822918673 +r_1815 glyoxylate exchange 9.57850476827586e-05 0.0015109177247277 1577.4045754321512 0.073384340490114 0.035266270520335 48.05694278207206 0.0038248494378774 0.0110541710469246 289.0093120386696 0.2515611061141398 0.1724051693165091 68.53411164374687 0.0313894705741214 0.0821332420467765 261.6585770468202 0.0001652940229211 0.0042383320670311 2564.116954823534 0.0137397032398539 0.0459131881437314 334.1643363195334 0.0039831532281838 0.0366595094243432 920.3640262932688 0.007432507743141 0.084780718883192 1140.6744777552396 +r_1816 glyoxylate transport 9.57850476827586e-05 0.0015109177247277 1577.4045754321512 0.073384340490114 0.035266270520335 48.05694278207206 0.0038248494378774 0.0110541710469246 289.0093120386696 0.2515611061141398 0.1724051693165091 68.53411164374687 0.0313894705741214 0.0821332420467765 261.6585770468202 0.0001652940229211 0.0042383320670311 2564.116954823534 0.0137397032398539 0.0459131881437314 334.1643363195334 0.0039831532281838 0.0366595094243432 920.3640262932688 0.007432507743141 0.084780718883192 1140.6744777552396 +r_1817 glyoxylate transport 3.4076750145296944e-05 0.0008021713275869 2354.0135845308287 6.876667228814223e-05 0.0015362493163629 2234.002701084381 6.227900303070467e-05 0.0013092882146074 2102.294755685087 0.0001109159471819 0.0021299674489049 1920.3437404813244 0.0001397886425483 0.0034057095838575 2436.3278173178774 0.0001119133829763 0.0027953978417271 2497.8226619409947 0.00022996507879 0.0054166173426736 2355.408643422244 0.0002900860348765 0.0073918722783082 2548.1655059516897 0.0001860408885196 0.0058815242116552 3161.4148150198494 +r_1818 guanine exchange -7.156000000000372e-10 4.5602437615367556e-10 -63.72615653348962 -5.551900078452678e-10 5.443195422597957e-10 -98.04202787660728 -6.362000000000315e-10 4.873367002513873e-10 -76.60117891407783 -6.406383049882803e-10 5.007485053855433e-10 -78.16399698339988 -7.300000000000383e-10 4.489324092350832e-10 -61.49759030617255 -6.48445459092031e-10 4.811280472844875e-10 -74.19714958882969 -7.310466114863266e-10 4.60404403719796e-10 -62.978802785738274 -6.332643812607604e-10 5.077155890710949e-10 -80.1743480440647 -7.591930888543147e-10 4.3463242009547247e-10 -57.24925930916584 +r_1819 guanine transport -1.6499033257707783e-10 3.7451931182776076e-10 -226.99470082757617 -1.254e-10 3.3180846790259543e-10 -264.6000541488002 -2.9279186575159674e-10 4.5865469854417904e-10 -156.6487160996814 -1.6679999999999872e-10 3.7337064845570847e-10 -223.8433144218893 -2.802000000000047e-10 4.4958690558905197e-10 -160.45214332228568 -1.0897212815549128e-10 3.4066679241995865e-10 -312.61827972549503 -2.7100000000000403e-10 4.449703357752549e-10 -164.19569585802518 -2.4521242148820406e-10 9.258973669761827e-10 -377.5899121899593 -2.9597926654891315e-10 4.730977112925271e-10 -159.84150403803483 +r_1820 guanosine exchange -2.4868554073741676e-10 4.779567300462004e-10 -192.19321261257704 -2.279902078426914e-10 4.2201390064222915e-10 -185.1017658325967 -5.028128808309733e-10 5.039380340599612e-10 -100.22377175921358 -2.720000000000041e-10 4.4593247376057055e-10 -163.945762411972 -3.1860000000000756e-10 4.685487675680253e-10 -147.0648987972424 -2.88759789186287e-10 4.565395904313146e-10 -158.1035890481234 -3.76400000000012e-10 4.88232233822004e-10 -129.71100792295132 -4.242000000000154e-10 4.983011346607227e-10 -117.4684428714532 -5.720952928885577e-10 1.197816441504925e-09 -209.37358800088148 +r_1821 guanosine kinase 7.382241698379543e-05 0.0023335174762004 3160.9876397202006 0.0001612584548679 0.0046527925359067 2885.3014495993384 4.501238873543185e-05 0.0022504534505007 4999.631243140942 0.0001002322138696 0.0040911991247063 4081.720802881379 0.0002009216708433 0.0082009443174901 4081.662412554802 0.0001641622905692 0.0067005640975846 4081.6706896262167 0.0003020086318552 0.0123269710870247 4081.661842345843 0.0007639563787099 0.0241487417723781 3161.010555754006 0.0004403330083192 0.0179729099245013 4081.6631015472 +r_1822 guanosine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1823 guanosine transport 2.4868554073741676e-10 4.779567300462004e-10 192.19321261257704 2.279902078426914e-10 4.2201390064222915e-10 185.1017658325967 5.028128808309733e-10 5.039380340599612e-10 100.22377175921358 2.720000000000041e-10 4.4593247376057055e-10 163.945762411972 3.1860000000000756e-10 4.685487675680253e-10 147.0648987972424 2.88759789186287e-10 4.565395904313146e-10 158.1035890481234 3.76400000000012e-10 4.88232233822004e-10 129.71100792295132 4.242000000000154e-10 4.983011346607227e-10 117.4684428714532 5.720952928885577e-10 1.197816441504925e-09 209.37358800088148 +r_1824 H+ diffusion 0.0001391413910733 0.0031109802385262 2235.840977675883 0.0001866889036529 0.004986500599084 2671.0214166528035 0.0001957848439209 0.0046120764036668 2355.68612528958 0.000229660444028 0.0061347494203051 2671.2259685238914 0.0006462204650928 0.0144412929753046 2234.731605602871 0.0005357254018075 0.0119687466081781 2234.1196754522107 0.0009898977037152 0.0221169778017605 2234.2690278755567 0.0009056063949713 0.0261299235516171 2885.3510417672965 0.0012741501428097 0.0300137723102718 2355.591488149584 +r_1825 H+ diffusion -0.0014440820266492 0.0128911319770899 -892.686962319023 -0.0028881066595828 0.023234547185318 -804.4906204632368 0.0016673986679152 0.0194788341570355 1168.2169676547633 0.0021506301061631 0.0293646530837382 1365.397657160429 -0.0015230684982337 0.0596384303890031 -3915.676179906925 0.0040236633648424 0.0482382778523138 1198.8646533854032 -0.0047785605122915 0.0901308168791255 -1886.1499534700577 -0.0124243950097054 0.1349499022409123 -1086.1688004566408 -0.0085064613405127 0.1298039534641153 -1525.9453757335389 +r_1826 H+ diffusion -0.0004838229996477 0.0066321399490382 -1370.7781469394024 -0.0009133957636492 0.013404438385925 -1467.5389266500456 -0.0007028796002777 0.0102467637198835 -1457.826307070939 -0.0008706643521577 0.0137868757684812 -1583.4891751698638 -0.0019443118961388 0.0294970592734046 -1517.0950366544696 -0.0015312299262331 0.0218249311124021 -1425.3203087593342 -0.0027137140874805 0.0419658967074047 -1546.437662722495 -0.0039698074053915 0.0628451735899408 -1583.0786527474609 -0.0033756371119494 0.0538257661054866 -1594.5365073440132 +r_1827 H+ diffusion -0.0044525207929966 0.0132290652396547 -297.1140586353382 -0.0077877246202875 0.0232733724719392 -298.84688540874475 -0.0062924026177378 0.0194489131428076 -309.08564382041226 -0.0100897162312658 0.0296934186693722 -294.29389279907497 -0.0198938830390577 0.059293792153741 -298.0503707462701 -0.0160163512529322 0.0477049006116982 -297.8512387642876 -0.0315438115889948 0.0911056665435889 -288.8226309827897 -0.0464195080594504 0.1357649949712409 -292.474006396974 -0.0444699687912858 0.1309532051226761 -294.47559483859374 +r_1829 H+ diffusion 0.0003701503371634 0.0167874042491746 4535.29351825587 -0.0020827419087789 0.0389875639085962 -1871.9344794600108 -0.0090808598054563 0.0649004895476064 -714.6954246404081 -0.0263540423065692 0.1535749923599968 -582.7378987007075 -0.0137374538113665 0.1369457333648807 -996.8785718614732 -0.0233241221345379 0.1676723054232756 -718.8793835674085 -0.0169474329852352 0.2077740131344854 -1225.9910590323643 0.0022415094888426 0.2242662172339998 10005.142443086115 -0.0413056550339388 0.3503756753285234 -848.2511051831441 +r_1830 H+ diffusion -0.0012424840056895 0.0048887508183988 -393.4658954169467 -0.0026811295895245 0.0097241552637452 -362.688745137077 -0.0019394337077363 0.0076870662332678 -396.35622514986096 -0.0030001388222793 0.0114399059276697 -381.3125526964194 -0.0057266451468785 0.0224445440648146 -391.9318115432476 -0.0046988442313982 0.0179123503576391 -381.2075794712785 -0.0089499545311954 0.0345374447000434 -385.89519734051817 -0.0130973358943767 0.0505168764832147 -385.7034506147464 -0.0125937315669184 0.049252296717932 -391.08580690499656 +r_1831 H+ diffusion 3.244607458252692e-10 1.542992037488812e-09 475.5558437629167 7.884707577977307e-10 1.0505228296758583e-09 133.2354839144653 1.0278170742224868e-09 2.177607203937944e-09 211.8671949077359 -0.0004024203099432 0.0116111030607207 -2885.317359444224 1.1193814639613022e-09 1.0451828618154071e-09 93.37146410453154 8.61431346228772e-10 1.42067008551058e-09 164.91971086611582 8.812943851027447e-10 1.751925909175706e-09 198.7900908924388 1.956898008525301e-09 2.924580385683257e-09 149.44981153551237 2.368942181727092e-10 1.0485985555529675e-09 442.6442163263269 +r_1832 H+ exchange 0.0907914963229948 0.0109421939944587 12.052003147443932 0.233347175535214 0.0299941483018575 12.853872446950271 0.5903644652775687 0.0528818941729457 8.957499524989615 1.4673217467297066 0.0398834700472592 2.7181134700790395 1.4389259017976663 0.1805610105790109 12.548318878229525 1.030939497721185 0.0433709875732961 4.206938202403198 1.7693081760015648 0.2096122346067585 11.847129711481823 1.921829355088541 0.2265301303985813 11.787213562889136 3.209621403482182 0.3690346037678255 11.497761180413756 +r_1833 hexacosanoyl-CoA transport 1.34639227639814e-05 0.0002342691041473 1739.9765896906588 0.0001686930073039 0.0036069975577742 2138.2021788692955 0.0001822547405635 0.0031069366973041 1704.7220213299518 0.0005124658730046 0.006564777950554 1281.017585047056 0.00043350410762 0.008785705322483 2026.67175882516 3.5214513303809605e-05 0.0007333547166782 2082.5354317731108 0.000878413731373 0.0159754700532027 1818.672623460944 0.0008738483864412 0.0191451214012743 2190.897379720982 0.0010693434500053 0.0208449083592115 1949.3183746632192 +r_1834 hexadecanal exchange 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1835 hexadecanoate (n-C16:0) transport -4.562682481435388e-06 0.0001288511146439 -2824.0210702421973 -2.324596749295977e-06 8.219038048610883e-05 -3535.683361469074 -8.314570761104683e-07 5.884794148568413e-05 -7077.68845518437 -2.367149854686172e-06 0.0001183839968728 -5001.119664583175 -1.951117037305336e-05 0.0004875291390674 -2498.7180663483846 -8.792332544265313e-06 0.0002982113455569 -3391.7205025582325 -2.492304110946165e-05 0.000658015908189 -2640.191079808839 -2.368662639513025e-05 0.0007952131452234 -3357.224165054525 -1.0757677104443864e-05 0.000537874595482 -4999.913924353032 +r_1836 hexadecenoate (n-C16:1) transport -2.795258047429643e-06 9.703156594655466e-05 -3471.2918914867005 -2.1141633609395955e-06 7.530624208900814e-05 -3561.9878520427987 -1.5548762331687946e-06 7.776339583013826e-05 -5001.2595325133125 -1.110007762170251e-06 7.854834607106569e-05 -7076.378089238811 -4.58675696832426e-06 0.000229349897871 -5000.262700965699 -1.417834518110378e-05 0.0004088529159853 -2883.6434066385923 -1.723801301528535e-05 0.0005449174323286 -3161.138304312812 -1.5553759805533687e-05 0.000634879397711 -4081.838768560332 -4.021412350754449e-05 0.001004667581588 -2498.295359836752 +r_1837 L-histidine transport, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1838 homocitrate synthase 0.0048132272607936 3.5562686012007606e-05 0.7388532492883723 0.0081824452387841 5.0480819421499503e-05 0.6169405104262032 0.0225945993771964 6.366146575899788e-05 0.2817552313994467 0.0379330185749148 0.0001026975097591 0.270733818760794 0.0408486101048924 0.0001719910494753 0.4210450466582642 0.0571904194436072 0.0001665740527099 0.2912621630170617 0.0662291317364671 0.0003129107706179 0.4724669679546817 0.0833496439463349 0.0004892934872609 0.587037285457352 0.0881925294363884 0.0004440169619329 0.5034632352315446 +r_1839 hydrogen peroxide transport -2.0707676820521754e-09 1.9621362356428834e-09 -94.75404955607402 -1.6880111769734623e-09 2.046179754309352e-09 -121.21837711869136 -2.654428142150742e-09 1.8857375130700263e-09 -71.04119652461617 -1.6422190909762611e-09 1.926255531240496e-09 -117.29589199303376 -2.323018430929602e-09 1.9032747389811647e-09 -81.9311079774572 -5.556051799579467e-10 1.6251313634242966e-09 -292.4975183901816 -1.245420960212124e-09 1.931375218324331e-09 -155.07810451458698 -2.0130000000000616e-09 1.9839400705768797e-09 -98.5563870132548 -2.3033616022424282e-09 1.7323565858049871e-09 -75.2099272697113 +r_1840 hydroxymethylglutaryl-CoA transport -0.0053001906480806 0.0018711292439558 -35.303055459588755 -0.0083367862376668 0.0011828775915692 -14.188652051852454 -0.0192965990028716 0.002048450636081 -10.615604520652536 -0.0286193723832947 0.0026701614973804 -9.329909341195169 -0.0407809096081129 0.0061833091913512 -15.162264036702927 -0.0480584479286974 0.0057014975418115 -11.863673896149596 -0.0542910123576858 0.0101436805416246 -18.683903838069867 -0.0639823804599395 0.0129443223468359 -20.23107338893176 -0.0724009683014875 0.0141460310987399 -19.538455673457204 +r_1841 hypoxanthine exchange 1.1873138216459351e-05 0.0002353371458728 1982.0972482794184 6.311293291213394e-05 0.0009279147367292 1470.2449940348895 4.905960307387241e-05 0.000767862745547 1565.1629802036025 8.727643858747028e-05 0.0012565585878701 1439.745489397758 0.0001432367477786 0.0022606463703748 1578.2586559893657 5.138661136804984e-05 0.0009459237970132 1840.7981609026751 0.0002483641910394 0.0036537488948023 1471.1254788826038 0.0003766781639181 0.0055419137574805 1471.2596291313314 0.0003775125252668 0.0054368311916072 1440.172398985728 +r_1842 hypoxanthine transport -1.1873138216459351e-05 0.0002353371458728 -1982.0972482794184 -6.311293291213394e-05 0.0009279147367292 -1470.2449940348895 -4.905960307387241e-05 0.000767862745547 -1565.1629802036025 -8.727643858746978e-05 0.0012565585878701 -1439.7454893977665 -0.0001432367477786 0.0022606463703748 -1578.2586559893657 -5.138661136804984e-05 0.0009459237970132 -1840.7981609026751 -0.0002483641910394 0.0036537488948023 -1471.1254788826038 -0.0003766781639181 0.0055419137574805 -1471.2596291313314 -0.0003775125252668 0.0054368311916072 -1440.172398985728 +r_1843 indol-3-ylacetaldehyde exchange -4.894038598010247e-11 4.029036719164882e-09 -8232.539728646507 1.9341816829340664e-05 0.000373995106341 1933.6089760387204 1.0507679603105607e-05 0.0003335123771478 3173.986929038428 2.515954527407175e-05 0.000628538081426 2498.2092266739737 3.888870757632492e-05 0.0011220392229324 2885.2571681131385 3.627780193798224e-05 0.0009692485206597 2671.73993153371 5.781833253988624e-05 0.001603590849551 2773.498956312594 0.0001713681404622 0.0033424213982071 1950.433370631428 0.0001767569824028 0.0035006959897806 1980.5135515395907 +r_1844 indole-3-acetaldehyde transport 5.489032114256526e-06 0.0001947375128816 3547.756850901059 1.193524094841811e-06 8.441790889878996e-05 7072.995783129008 1.658267857898149e-05 0.0004142866618003 2498.3096658788018 1.7536067102558057e-05 0.0005061652106512 2886.423778439057 3.5849263033662595e-05 0.001034696310995 2886.241510804425 3.234238452762913e-05 0.0009331796077786 2885.314801020427 4.571012513752965e-05 0.0014449686612018 3161.156651517283 6.972000414493966e-05 0.0022038641112989 3161.021199478604 3.999019115757845e-05 0.0016323179148247 4081.795729339484 +r_1845 indole-3-acetaldehyde transport -4.894038598010246e-11 4.029036719164882e-09 -8232.53972864651 1.9341816829340664e-05 0.000373995106341 1933.6089760387204 1.0507679603105607e-05 0.0003335123771478 3173.986929038428 2.515954527407175e-05 0.000628538081426 2498.2092266739737 3.888870757632492e-05 0.0011220392229324 2885.2571681131385 3.627780193798224e-05 0.0009692485206597 2671.73993153371 5.781833253988624e-05 0.001603590849551 2773.4989563125946 0.0001713681404622 0.0033424213982071 1950.433370631428 0.0001767569824028 0.0035006959897806 1980.5135515395907 +r_1846 indole-3-acetate transport 2.1740000000000087e-10 5.958256805881741e-10 274.06885031654645 7.41035538566229e-12 8.620349940619255e-10 11632.84281520167 1.1260000000000024e-10 5.79645096319773e-10 514.7825011720886 4.790398202756922e-10 8.424896030848833e-10 175.8704741079816 8.200000000000013e-11 5.330411115151597e-10 650.0501359940961 6.206272622748691e-12 3.647443866389573e-10 5877.028110270412 -1.0120000000000088e-10 6.537920531864501e-10 -646.0395782474745 3.1999999999999986e-11 4.3705171643704676e-10 1365.7866138657714 9.000000000000061e-11 3.958930995474239e-10 439.8812217193569 +r_1847 inosine exchange -5.928000000000282e-10 4.946080139034184e-10 -83.43589978127449 -4.0080000000001375e-10 4.91332516253786e-10 -122.5879531571281 -6.128000000000297e-10 4.883890506276201e-10 -79.69795212591326 -2.7680000000000446e-10 4.5102377375132157e-10 -162.94211479454995 -4.1209515550747756e-10 4.9602721427813e-10 -120.36715492743272 -5.234000000000227e-10 5.02695713723625e-10 -96.04427086809385 -3.866000000000127e-10 4.91516792949678e-10 -127.13833237187328 -5.93000000000028e-10 4.953787238225056e-10 -83.5377274574169 -6.120000000000294e-10 4.889824340036777e-10 -79.89909052347288 +r_1848 inosine transport 5.928000000000282e-10 4.946080139034184e-10 83.43589978127449 4.0080000000001375e-10 4.91332516253786e-10 122.5879531571281 6.128000000000297e-10 4.883890506276201e-10 79.69795212591326 2.7680000000000446e-10 4.5102377375132157e-10 162.94211479454995 4.1209515550747756e-10 4.9602721427813e-10 120.36715492743272 5.234000000000227e-10 5.02695713723625e-10 96.04427086809385 3.866000000000127e-10 4.91516792949678e-10 127.13833237187328 5.93000000000028e-10 4.953787238225056e-10 83.5377274574169 6.120000000000294e-10 4.889824340036777e-10 79.89909052347288 +r_1849 inositol hexakisphosphate transport -8.85854118559832e-05 0.0018062654408613 -2039.010039031992 -0.0001612583657858 0.003288043652938 -2038.9910544572888 -0.0001362403529252 0.0027779454774322 -2039.0034360502248 -0.0001695914617661 0.0037466267787462 -2209.2071969479657 -0.000267595920282 0.006685257147129 -2498.2657209728804 -0.0003009503487558 0.0064098734128093 -2129.877383199316 -0.0006028453642561 0.012292123340204 -2039.0176435000053 -0.0006875183469514 0.0161920052859611 -2355.137918538416 -0.0005857573303905 0.0146339719985448 -2498.2994218419567 +r_1850 insosine kinase 0.0001845534975235 0.0034257743641443 1856.250035959119 0.0003394627905154 0.0061715844441438 1818.0444562932023 0.000222286739057 0.0044778348922429 2014.440857442689 0.0003986025421951 0.007407611843076 1858.395534128208 0.0006790192777007 0.0132973807333993 1958.3215337311924 0.0007339817374791 0.0131378465208618 1789.9418813857262 0.0013644673015092 0.0224186603703578 1643.033903821663 0.0015498675790895 0.031291799778475 2018.998280927808 0.0019207190889572 0.0341353923202854 1777.2194026986956 +r_1851 IPC transport 0.0001630318810186 0.0020747083768584 1272.5783226541323 0.0002927873509762 0.003791706786434 1295.0377718815037 0.0002315136778375 0.0031173735561142 1346.5180913853908 0.0002938883448406 0.0042418622163347 1443.3584355430685 0.000780452906911 0.0098291854875659 1259.420703097747 0.0005039135401758 0.0070888197951199 1406.75318878044 0.0008195063196659 0.0123137277956074 1502.5787477303525 0.0017466366232343 0.0221509429077513 1268.2055679522794 0.0016924988820525 0.0213409267098703 1260.912307604601 +r_1852 IPC transport 0.0001152038689364 0.0017748811193325 1540.6436743121287 0.0001827472261931 0.0030133179275912 1648.8994062248833 0.0001533919382045 0.0025377442784509 1654.418288310702 0.0002378706034712 0.003810702911662 1602.0066607862905 0.0006811391347235 0.0092159691544343 1353.0229999448022 0.0003971435930939 0.006210350980353 1563.7545432802374 0.0007919162821742 0.0121773209934838 1537.7030713461388 0.0010252879822997 0.0170460396962813 1662.5611526282487 0.0011875375235318 0.0179121726354397 1508.3458232265357 +r_1853 IPC transport 0.0001202081333907 0.0018075982334733 1503.723735229746 0.0001759364562383 0.0029510674090309 1677.3484428001084 0.0001622550934567 0.0026274325996926 1619.3221079941995 0.0002149551830777 0.003611180495016 1679.9690257808772 0.0004722194605249 0.0076036483580981 1610.1937750819775 0.0005134517686218 0.0072446041351047 1410.9609855954964 0.0007363768198014 0.0116920924463573 1587.7865967467485 0.0011713145567044 0.0181504755833058 1549.5816627066724 0.000886545150895 0.015498402997947 1748.179772039829 +r_1854 IPC transport 0.0001425043755035 0.0019332762878117 1356.6434581258131 0.0001847471091717 0.0029831548934277 1614.7234491528138 0.0002030285591516 0.0028968150098536 1426.8017376261507 0.0003436219564938 0.004630295631608 1347.4970222664365 0.0005799468787098 0.0085187937452228 1468.8920758007305 0.0004294487569577 0.0065924041374883 1535.0851599128432 0.0010237187302529 0.01382165051992 1350.1414120365466 0.0012034583306048 0.0185162484345218 1538.5865853133237 0.0009369689624292 0.0160431988107286 1712.2444236715928 +r_1855 IPC transport 0.0001055046914975 0.00168855171051 1600.4517775869272 0.0003006809335163 0.0038337301487169 1275.0160457078234 0.0002040194397233 0.0029095728783288 1426.125315447177 0.0003046980293153 0.0043307138416567 1421.3133742241232 0.0007131553984439 0.0093162971962504 1306.3488289618929 0.0006736987668506 0.0081876022326101 1215.3209469100257 0.0010716990373946 0.0139921626080429 1305.6055963303295 0.0014575619229983 0.0202239882635294 1387.521719964159 0.001607017461336 0.0207473064646146 1291.0442458643563 +r_1856 IPC transport 0.0001874376926947 0.0022491547798998 1199.947965408708 0.0002383711334472 0.0034192907397435 1434.4399383829611 0.0001545152790783 0.0025493819478158 1649.9222361845732 0.0004230356422087 0.00503755744464 1190.8115870186598 0.0007327893733117 0.0094788577936519 1293.5310116212054 0.0006523181230012 0.0081295785933932 1246.2598089394282 0.0009740566518443 0.0134178146255621 1377.5189153686033 0.0017295329274589 0.0217146045153593 1255.518421800886 0.0015585641101214 0.0204599088833889 1312.7409229123243 +r_1857 IPC transport 0.0001380623986727 0.0019476825871037 1410.726313483793 0.0003661871844822 0.0042504911903303 1160.7427486409854 0.0002926298808747 0.003440549946541 1175.7343222286486 0.0003056298809264 0.0043619088540761 1427.1866483912906 0.0008690325217096 0.0102435666323119 1178.7322541347569 0.000506436443417 0.0070475384005803 1391.593849966548 0.0012421481492471 0.0151260081720289 1217.7297998790957 0.0016362136754639 0.0213833765767209 1306.8816681695505 0.0014047533730844 0.0194691245358192 1385.946096222577 +r_1858 IPC transport 6.695821585821268e-05 0.0013575085262339 2027.3965021836048 0.0002278331974365 0.0033508210365026 1470.7343241477918 0.0001972529715154 0.0028572982613491 1448.545103983237 0.0002946688058258 0.0042622820097452 1446.4652944174804 0.0005031680931695 0.0079326995215415 1576.550586022406 0.0005144213373993 0.0072576080898461 1410.8295209013277 0.00079360165938 0.012208636301465 1538.3834140420774 0.0013320709921132 0.0194364449273845 1459.1147951168996 0.0015672414435809 0.0206047927347832 1314.7171942890643 +r_1859 IPC transport 0.0001113798268811 0.0017379859254081 1560.4135632778732 0.0002189247326579 0.0032511698739392 1485.0628498966514 0.0002086497213229 0.0029493343253651 1413.5337956191474 0.000225086706816 0.0037339059700481 1658.8744945739973 0.0005334470210859 0.0080312370169893 1505.536013799387 0.0004723268452726 0.0069189308949783 1464.8608192033305 0.0009096021931077 0.012913166539399 1419.649890605432 0.0013297217136472 0.0192736674118076 1449.451205767122 0.0013300735275623 0.0190329122794935 1430.9669266462042 +r_1860 IPC transport 0.0001595685589846 0.0020768142081138 1301.5184327842846 0.00028009281641 0.0037213104703721 1328.5990401567983 0.0002187428703392 0.003015374226757 1378.5017185154825 0.0003842467722463 0.004820466927946 1254.5237269697504 0.0006259284694508 0.0087778027572488 1402.3651560298272 0.0006131383991704 0.0078702230121772 1283.59649678211 0.0013172456777205 0.0155736750356035 1182.2908436149585 0.0018592220460315 0.0227001282969892 1220.9476724655729 0.0018384672958292 0.0220954901114685 1201.842978746173 +r_1861 iron(2+) exchange -1.4648869034901352e-05 0.0001439642008957 -982.766659683918 -9.130916687013204e-06 0.0001060044913905 -1160.9402979370598 -1.70335578353058e-05 0.0001678545572736 -985.4345104916548 -1.781343618359452e-05 0.0002030933898471 -1140.1134949705531 -5.079806042469869e-05 0.0005130157493933 -1009.9120814933514 -4.507729077978233e-05 0.0004661299012657 -1034.068137641565 -4.787220384359442e-05 0.0005824691809608 -1216.7168715772625 -0.0001020024408182 0.0011187936343705 -1096.830257586241 -0.0001023385553786 0.0010814225039505 -1056.710738146393 +r_1862 isoamyl acetate exchange 3.00551439968675e-05 0.000867177218328 2885.2871855095395 1.1903058752903195e-05 0.000347545223083 2919.7975940286133 1.3370242619708243e-05 0.0005457284926638 4081.664844730789 3.238450417219912e-05 0.0009343922788889 2885.3067316406787 2.6288788417819488e-05 0.0013143076339863 4999.498695403614 1.8204910492443603e-05 0.0010123216500618 5560.706549378493 0.0001185096829893 0.0034193692443564 2885.3078989871665 5.99741161943626e-05 0.0029984054878992 4999.499247612278 5.760374706167921e-05 0.0028798990646271 4999.499531763882 +r_1863 isoamyl alcohol transport 9.7805063248744e-05 0.0016696615643101 1707.1320326880875 3.2901122135398375e-05 0.0006447976176666 1959.804334372285 7.630029463703887e-05 0.0014403287776165 1887.7106365948312 0.0001095725248995 0.0018714113118342 1707.9202232029563 0.000304149837262 0.0049267429207409 1619.840722287424 0.0002374368693124 0.0043443629906987 1829.6918264120663 0.000455899836166 0.0073844481973521 1619.7523253029708 0.0005410311313582 0.0098705994721181 1824.4050850340725 0.0005256417806227 0.0095864980831635 1823.7701865720423 +r_1864 isoamyl alcohol transport -5.247841301084752e-05 0.0012131569100951 -2311.725603905658 -1.796080373536082e-05 0.0004797354206987 -2671.013100345149 -2.7376846541264165e-05 0.0008653885547307 -3161.0235073142703 -4.604295817903487e-05 0.0012204309432414 -2650.6353881432515 -0.0001454947566655 0.0034266002401439 -2355.136582702792 -0.0001370794271951 0.003332456012611 -2431.04022302916 -0.0001939714839014 0.0048459707723054 -2498.2903026958857 -0.0002209870716657 0.0063761856843064 -2885.320682447711 -0.0002125744326901 0.0061334265023139 -2885.307713019049 +r_1865 isoamylol exchange 9.7805063248744e-05 0.0016696615643101 1707.1320326880875 3.2901122135398375e-05 0.0006447976176666 1959.804334372285 7.630029463703887e-05 0.0014403287776165 1887.7106365948312 0.0001095725248995 0.0018714113118342 1707.9202232029563 0.000304149837262 0.0049267429207409 1619.840722287424 0.0002374368693124 0.0043443629906987 1829.6918264120663 0.000455899836166 0.0073844481973521 1619.7523253029708 0.0005410311313582 0.0098705994721181 1824.4050850340725 0.0005256417806227 0.0095864980831635 1823.7701865720423 +r_1866 isobutanol exchange 0.0001424187508611 0.00206126938717 1447.3300564054991 4.280171970043456e-05 0.0008384893714147 1959.008603587004 0.0001270724633292 0.0021385423015663 1682.9313334593326 9.931815719674928e-05 0.0020261503770156 2040.06038191168 0.0002584018480022 0.0052448110684036 2029.711129758712 0.000537919371417 0.0069660566471776 1295.000146365158 0.0004317718645213 0.0082807036076121 1917.84233481523 0.000810036753218 0.0139498816766062 1722.1294739019886 0.0007563374522166 0.0133604986340671 1766.4732316123927 +r_1867 isobutyl acetate exchange 3.937937739591677e-05 0.0010629274247474 2699.1981464330133 1.04290842546694e-05 0.0003686097732753 3534.440457802585 2.267258038138728e-05 0.0008013572873004 3534.477654595812 2.789989699596347e-05 0.0009427805091496 3379.154085357616 5.023043519496592e-05 0.0020502365927756 4081.662013912038 3.447919340937317e-05 0.0017237869674911 4999.499109577487 0.0001623522695679 0.0044251599286588 2725.653260305917 7.639561086602784e-05 0.0038193981067658 4999.499399859181 6.831403631806003e-05 0.0034247741943154 5013.280401658963 +r_1868 isobutyl alcohol transport 0.0001424187508611 0.00206126938717 1447.3300564054991 4.280171970043456e-05 0.0008384893714147 1959.008603587004 0.0001270724633292 0.0021385423015663 1682.9313334593326 9.931815719674928e-05 0.0020261503770156 2040.06038191168 0.0002584018480022 0.0052448110684036 2029.711129758712 0.000537919371417 0.0069660566471776 1295.000146365158 0.0004317718645213 0.0082807036076121 1917.84233481523 0.000810036753218 0.0139498816766062 1722.1294739019886 0.0007563374522166 0.0133604986340671 1766.4732316123927 +r_1869 isobutyl alcohol transport -3.793154013768106e-05 0.0012242994000625 -3227.655390787289 -2.3187514060440483e-05 0.0006193436251041 -2671.022100470984 -5.493920905301429e-05 0.0014068497851739 -2560.739059450904 -4.964069493098872e-05 0.0014335391890013 -2887.8306216186406 -4.514391578995459e-05 0.0021861985810782 -4842.731390981235 -0.0001444784471434 0.0039354931525847 -2723.930960219901 -0.000109639758281 0.0040957631976393 -3735.655077913124 -0.0001295473135519 0.0054230937172707 -4186.187709016362 -0.000192645577228 0.0068090063605889 -3534.4732324314364 +r_1870 isobutyraldehyde exchange 0.000289551849178 0.0037383278207248 1291.0737166199808 5.6897197581841344e-05 0.0010391901531869 1826.4346880919384 0.0002141584293282 0.0030305113433658 1415.079178938572 0.0002039828832232 0.0030765376340333 1508.2332328181674 0.0004025555437255 0.007350493420014 1825.957568982136 0.0005774789569348 0.0084871830781564 1469.6956445313413 0.0006285748652884 0.0111190771525681 1768.934420797385 0.0011918460802943 0.018890964258679 1585.017106740271 0.0010638209029215 0.0177226422859973 1665.9422875904877 +r_1871 L-1-pyrroline-3-hydroxy-5-carboxylate spontaneous conversion to L-4-hydroxyglutamate semialdehyde -2.6199999999999952e-11 4.502822568369249e-10 -1718.63456807987 1.6199999999999887e-10 8.140568393592225e-10 502.5042218266842 -3.5840000000001047e-10 7.411202951332462e-10 -206.7857966331541 6.460000000000022e-11 7.94577315698171e-10 1229.9958447340064 -4.239999999999988e-11 4.897450459596443e-10 -1155.0590706595422 -2.8599999999999945e-11 3.6139751193433765e-10 -1263.627664106078 2.439999999999996e-11 6.766802932285323e-10 2773.2798902808745 1.7999999999999832e-10 6.726741396097037e-10 373.70785533872777 -2.7599999999999942e-11 5.212413821980229e-10 -1888.555732601536 +r_1872 L-2-amino-3-oxobutanoate decarboxylation (spontaneous) 4.699999999999986e-11 2.1260301034557987e-10 452.34683052251165 1.0400000000000007e-11 1.0721072160827055e-10 1030.8723231564468 5.799999999999999e-12 7.594414725770827e-11 1309.3818492708324 4.4e-12 6.619302307087238e-11 1504.3868879743725 4e-12 7.200720108018439e-11 1800.18002700461 5.38e-11 2.2741130838336047e-10 422.6975992255772 2.2000000000000003e-12 4.6857220572966754e-11 2129.87366240758 3.8e-12 6.15330582975774e-11 1619.2910078309844 1.2e-12 4.8979993956325663e-11 4081.666163027139 +r_1873 L-alanine exchange -3.0200000000000635e-10 5.122972669241444e-10 -169.63485659739533 -1.0740000000000055e-10 5.512948623060562e-10 -513.3099276592676 9.740000000000086e-11 3.5261609098499243e-10 362.0288408470116 -3.3600000000000887e-10 6.462101186947526e-10 -192.32444008771893 4.379999999999988e-11 3.0512322106979444e-10 696.6283586068386 -4.3120000000001605e-10 5.608292662595179e-10 -130.06244579301878 1.4959999999999926e-10 4.1863455540388247e-10 279.8359327566073 6.040000000000015e-11 5.317973313964156e-10 880.4591579410833 5.920000000000012e-11 2.9413034956036235e-10 496.8418066898004 +r_1874 L-alanine transport 3.716583016995876e-05 0.0010257666244375 2759.972317978052 0.0002180534477219 0.0052668577076036 2415.397583770168 6.811886994056263e-05 0.003405476630663 4999.3146299028285 0.0001195181111674 0.0052051055944263 4355.076852857129 0.0003013819132449 0.0123014156225489 4081.670160661361 0.0003283213967679 0.0116044568534747 3534.480837286527 0.0004608955016583 0.0155033196604109 3363.738549113393 0.001145933009446 0.036223112751906 3161.0148632872933 0.0007600097160249 0.027270860742281 3588.225277554968 +r_1875 L-arabinitol exchange 3.5199999999999915e-11 2.1533748871669343e-10 611.7542293087897 1.0680000000000055e-10 3.252920579796049e-10 304.5805786325873 2.2000000000000003e-12 1.0861638690318042e-10 4937.108495599109 1.5399999999999997e-11 1.4821347255458162e-10 962.4251464583226 6.920000000000034e-11 2.6837616353361995e-10 387.8268259156338 3.879999999999989e-11 2.211432586993561e-10 569.9568523179297 2.679999999999995e-11 2.0709982633408502e-10 772.7605460227069 8.140000000000058e-11 2.898117288303351e-10 356.03406490212893 3.7599999999999895e-11 2.04437273802477e-10 543.7161537299935 +r_1876 L-arabinitol transport -3.5199999999999915e-11 2.1533748871669343e-10 -611.7542293087897 -1.0680000000000055e-10 3.252920579796049e-10 -304.5805786325873 -2.2000000000000003e-12 1.0861638690318042e-10 -4937.108495599109 -1.5399999999999997e-11 1.4821347255458162e-10 -962.4251464583226 -6.920000000000034e-11 2.6837616353361995e-10 -387.8268259156338 -3.879999999999989e-11 2.211432586993561e-10 -569.9568523179297 -2.679999999999995e-11 2.0709982633408502e-10 -772.7605460227069 -8.140000000000058e-11 2.898117288303351e-10 -356.03406490212893 -3.7599999999999895e-11 2.04437273802477e-10 -543.7161537299935 +r_1877 L-arabinoase transport 7.200000000000001e-12 1.3839071644470215e-10 1922.0932839541963 -2.400000000000001e-12 7.480213280257701e-11 -3116.755533440708 -1.8000000000000002e-12 4.2392445363355096e-11 -2355.135853519728 -2.2000000000000003e-12 5.094780795899906e-11 -2315.809452681775 -4.2e-12 6.769990144255447e-11 -1611.902415298916 -9.999999999999998e-13 1.0677677770026508e-10 -10677.67777002651 -6.8e-12 8.218948243056736e-11 -1208.6688592730495 -1.2e-12 7.745811740540989e-11 -6454.843117117491 -1e-12 4.68981864039265e-11 -4689.81864039265 +r_1878 L-arabinose exchange -7.200000000000001e-12 1.3839071644470215e-10 -1922.0932839541963 2.400000000000001e-12 7.480213280257701e-11 3116.755533440708 1.8000000000000002e-12 4.2392445363355096e-11 2355.135853519728 2.2000000000000003e-12 5.094780795899906e-11 2315.809452681775 4.2e-12 6.769990144255447e-11 1611.902415298916 9.999999999999998e-13 1.0677677770026508e-10 10677.67777002651 6.8e-12 8.218948243056736e-11 1208.6688592730495 1.2e-12 7.745811740540989e-11 6454.843117117491 1e-12 4.68981864039265e-11 4689.81864039265 +r_1879 L-arginine exchange -4.739999999999986e-11 2.1900418390183747e-10 -462.0341432528231 -4.770000000000192e-10 5.007206249285391e-10 -104.97287734350502 -1.2400000000000004e-10 3.3263512927207555e-10 -268.25413650973826 -9.460000000000088e-11 2.94054643946889e-10 -310.8400041721842 -2.176e-10 4.126551791258269e-10 -189.63932864238367 -4.0720000000001427e-10 4.921753826853475e-10 -120.8682177518002 -1.1180000000000042e-10 3.176805694228552e-10 -284.1507776590823 -9.691459878553828e-11 5.893144921906508e-10 -608.0760789143245 -5.218000000000226e-10 4.995744938795146e-10 -95.74060825593962 +r_1880 L-asparagine exchange -6.079999999999979e-11 4.107762254823116e-10 -675.6187919116991 -1.7397429665801075e-10 5.696024198883637e-10 -327.4060771218736 1.1026112781690888e-10 9.252571479009008e-10 839.1508106440843 -4.450000000000008e-10 8.36609217613911e-10 -188.00207137391223 1.1879999999999922e-10 9.217681331540367e-10 775.8991019815177 -1.0720000000000012e-10 5.612229095741367e-10 -523.5288335579629 1.729288462449914e-10 8.290117903697292e-10 479.3947385708302 1.2990355482326004e-10 9.031223166889748e-10 695.2252522401836 1.9179999999999576e-10 8.327973764932447e-10 434.2009262217222 +r_1881 L-aspartate exchange -3.038000000000065e-10 5.082885316887356e-10 -167.31024742881007 -1.9259999999999903e-10 4.6556265928223724e-10 -241.7251605826789 5.720000000000271e-10 6.73280522020534e-10 117.70638496861928 -4.3680000000000655e-10 7.267127233483838e-10 -166.3719604735286 5.386000000000254e-10 7.114852649608624e-10 132.09900946172087 -2.4900000000000224e-10 5.346551891025144e-10 -214.7209594789195 6.738000000000345e-10 5.781525854671752e-10 85.80477670928252 5.812000000000272e-10 6.221607322833474e-10 107.04761395101828 4.674000000000219e-10 7.674992188987587e-10 164.20608020939724 +r_1882 L-carnitine transport 2.7205239943049736e-10 1.2444971406616724e-08 4574.4758850385015 3.4790757209309656e-05 0.001114824327074 3204.3692534973643 6.239098079712379e-06 0.0004411578430989 7070.859240591888 3.939861910666138e-05 0.0012987912424649 3296.5400105745944 5.435323303315745e-05 0.0022214492216007 4087.059955100669 2.004784617358757e-05 0.0011347584249585 5660.251057061304 7.701505115983141e-05 0.0031745583070714 4121.997271005111 0.000114697939081 0.0047492654462415 4140.671998375737 8.231915301117064e-05 0.0041155201681388 4999.468553302975 +r_1883 L-cysteine exchange -1.283576599320474e-10 5.973555711457473e-10 -465.3836564658376 -4.304373335200479e-11 8.313874517135624e-10 -1931.494754218015 -1.671745838342129e-11 4.127015664384677e-10 -2468.686070412139 -4.913519311911268e-12 4.822741710226159e-10 -9815.249323504138 -2.1316936499537143e-11 4.663231166681586e-10 -2187.570979902689 -1.0075608568913759e-10 4.886544633395105e-10 -484.9875419407959 -1.5339035127432654e-11 3.915818827322212e-10 -2552.8455960825586 -3.999999999999989e-11 3.7420316086469255e-10 -935.507902161734 -2.3179581529383464e-11 3.648844009389899e-10 -1574.1630213489673 +r_1884 L-erythro-4-hydroxyglutamate transport 1.0811999999999321e-09 4.2596108809337856e-10 39.39706697127316 1.770999999999908e-09 1.014083168647707e-09 57.26048383104233 1.267400000000102e-09 7.08235525451051e-10 55.88097881102999 1.5783999999998762e-09 1.0359865315817063e-09 65.63523388125871 1.134999999999918e-09 5.94344722471621e-10 52.36517378604969 1.052599999999938e-09 4.111776421580591e-10 39.0630478964548 1.3223999999998924e-09 1.0029254268799886e-09 75.84130572293331 1.262199999999919e-09 1.4220603401832364e-09 112.66521471900872 4.00800000000016e-10 1.4501654926218275e-09 361.8177376800823 +r_1885 L-erythro-4-hydroxyglutamate transport -7.940000000000003e-11 6.776337340300213e-10 -853.4429899622432 -1.4800000000000567e-09 1.719241448497436e-09 -116.1649627363088 1.931999999997854e-10 9.293258251536327e-10 481.0175078440295 -1.342000000000042e-09 1.5074118409020535e-09 -112.32577055901685 -2.8219999999999686e-10 1.0103302991906615e-09 -358.01924138578056 3.5320000000001347e-10 9.51751504430258e-10 269.46531835510234 -1.661400000000024e-09 1.375037521537897e-09 -82.76378485240625 -1.9838000000000067e-09 1.496524465919476e-09 -75.43726514363703 -4.2280000000000603e-10 9.231525345902681e-10 -218.34260515379725 +r_1886 L-glucitol exchange 2.9700000000000595e-10 5.4849901570927e-10 184.67980326911083 -9.939999999999606e-10 1.037600753211294e-10 -10.438639368323294 -9.733999999999675e-10 2.2249121436157806e-10 -22.85712085078955 -9.959999999999598e-10 8.237327886768806e-11 -8.270409524868613 -9.715999999999684e-10 2.2091446453351542e-10 -22.73718243449183 1.5579999999999906e-10 5.38501956237283e-10 345.6366856465252 -9.715999999999684e-10 2.0591726587170536e-10 -21.193625552872795 -7.994000000000282e-10 5.134319453175037e-10 -64.2271635373387 -9.763999999999666e-10 2.045761723223412e-10 -20.952086472997564 +r_1887 L-glutamate 5-semialdehyde dehydratase 0.0027956193866688 0.0024220367635364 86.63685675833281 0.0049637062207814 0.005560300210681 112.01912368225604 0.0126150641521117 0.0039224982498088 31.09376379312534 0.0212177758235923 0.0063800369082296 30.069301142938546 0.0233114604354622 0.0127627010728458 54.7486122037675 0.031726827728846 0.0081076820032406 25.554657000482567 0.037622168027117 0.0188455640283182 50.09164813344855 0.0476264925462513 0.0277630653445741 58.29332344306633 0.0502033082489496 0.0268961408085311 53.57443910898815 +r_1889 L-glutamate exchange -4.239999999999988e-11 2.0545238410985848e-10 -484.5575096930639 -5.920000000000012e-11 2.360222474688758e-10 -398.68622883255966 -6.980000000000036e-11 2.5483513923639937e-10 -365.09332268824943 -7.600000000000049e-11 2.6502461698778927e-10 -348.71660129972054 -5.720000000000007e-11 2.3224760018040846e-10 -406.02727304267177 -5.980000000000013e-11 2.3798169479480926e-10 -397.9627003257672 -5.6400000000000046e-11 2.3158101380120595e-10 -410.60463439930095 -7.480000000000047e-11 2.6309466691812127e-10 -351.7308381258284 -4.999999999999991e-11 2.1888257563447435e-10 -437.7651512689495 +r_1890 L-glutamate transport -2.963706042742488e-10 1.3920104413426652e-09 -469.68573173827934 -4.4856828004592364e-10 1.8367106597519327e-09 -409.4606643973786 -5.417263470571031e-10 7.990143320955665e-10 -147.4940874550713 -3.2979999999961685e-10 8.470982676738326e-10 -256.8521126970336 -1.2939999999894484e-10 9.672862908964912e-10 -747.5164535582525 -5.598977063475833e-10 8.067665149942767e-10 -144.09176995153427 -4.448000000000358e-10 8.597097069104193e-10 -193.28006000682336 -6.52799999999791e-10 7.39974102476098e-10 -113.35387599208562 -7.83000000000034e-10 6.089213061073141e-10 -77.76772747219513 +r_1891 L-glutamine exchange -1.6319999999999883e-10 3.722814509154901e-10 -228.1136341393951 -3.4880000000000985e-10 4.766382242323557e-10 -136.65086703908892 -2.7940000000000464e-10 4.4919482988902166e-10 -160.7712347491103 -2.8400000000000496e-10 4.5098190311295544e-10 -158.79644475808016 -2.552000000000028e-10 4.36475729236402e-10 -171.03280926191113 -1.89399999999998e-10 3.9237537089672975e-10 -207.1675664713485 -3.1780000000000753e-10 4.66097210163137e-10 -146.66369105195912 -2.682000000000038e-10 4.4351787068879837e-10 -165.36833359015367 -2.1659999999999998e-10 4.1196891105606607e-10 -190.1980198781469 +r_1892 L-glutamine transport 2.963706042742488e-10 1.3920104413426652e-09 469.68573173827934 4.4856828012502703e-10 1.836710659732551e-09 409.46066432085087 5.41726346887794e-10 7.990143322104206e-10 147.49408752237005 3.2979999999510665e-10 8.470982676755717e-10 256.8521127010735 1.2939999999894484e-10 9.672862908964912e-10 747.5164535582525 5.598977063475833e-10 8.067665149942767e-10 144.09176995153427 4.448000000000358e-10 8.597097069104193e-10 193.28006000682336 6.52799999999791e-10 7.39974102476098e-10 113.35387599208562 7.83000000000034e-10 6.089213061073141e-10 77.76772747219513 +r_1893 L-histidine exchange -2.5799999999999952e-11 2.918071114247633e-10 -1131.0353155998598 3.164000000000073e-10 5.347412735575349e-10 169.0079878500387 -3.93999999999999e-11 2.519133423747349e-10 -639.3739654181105 -5.2784934347455034e-11 2.3070659002616277e-10 -437.069010084477 -4.958849401345323e-11 2.330868875043129e-10 -470.0422792454173 -2.8399999999999945e-11 2.7642127585327357e-10 -973.3143515960356 -4.9599999999999905e-11 2.3653970112022444e-10 -476.89455871013087 -5.0999999999999934e-11 2.2980331136077868e-10 -450.5947281583902 -7.440000000000045e-11 2.857988386877113e-10 -384.1382240426205 +r_1895 L-homoserine transport -1.3788577596454603e-05 0.0005628360744845 -4081.900910716715 -3.719593720949142e-05 0.0009935194546742 -2671.042939659233 -1.766148720219578e-05 0.0008830060645074 -4999.613307749441 -5.0317476450802354e-05 0.0017784841921139 -3534.525810039057 -5.2090377782739286e-05 0.0026042765175622 -4999.534709508618 -1.7035373585473804e-05 0.0012046073456021 -7071.2117909129975 -0.0001557979195024 0.005506861081728 -3534.6178558179136 -5.9418307254227485e-05 0.0042015431284389 -7071.125588385055 -5.687447492442182e-05 0.0040216819281711 -7071.154386067505 +r_1896 L-homoserine exchange 1.3788577596454602e-05 0.0005628360744845 4081.9009107167153 3.719593720949142e-05 0.0009935194546742 2671.042939659233 1.766148720219578e-05 0.0008830060645074 4999.613307749441 5.0317476450802354e-05 0.0017784841921139 3534.525810039057 5.2090377782739286e-05 0.0026042765175622 4999.534709508618 1.7035373585473804e-05 0.0012046073456021 7071.2117909129975 0.0001557979195024 0.005506861081728 3534.6178558179136 5.9418307254227485e-05 0.0042015431284389 7071.125588385055 5.687447492442182e-05 0.0040216819281711 7071.154386067505 +r_1897 L-isoleucine exchange -4.5380000000001776e-10 5.241378674555283e-10 -115.4997504309184 -3.12400000000007e-10 5.68569163935962e-10 -182.0003725787289 -5.8072859936833906e-11 5.571640783928324e-10 -959.4224892641108 -4.4940000000001724e-10 5.09010273267314e-10 -113.26441327710155 4.1692433578195586e-11 5.91270024817671e-10 1418.1710542483056 -5.413568203581123e-10 5.395497928561782e-10 -99.66620398340253 4.4664660753457316e-14 5.704072009198171e-10 1277088.3989657625 -2.219999999999997e-11 5.65836720475833e-10 -2548.8140561974496 -5.999999999999998e-12 5.47013569090317e-10 -9116.892818171951 +r_1898 L-isoleucine transport 0.0018989840477181 0.0180879120654034 952.5046872899476 0.0045297682238293 0.0402104943319793 887.6943001288124 0.0034250444320576 0.0303800671254192 886.9977522355242 0.0047671658837435 0.0457572172410827 959.8410954634144 0.0094775121295583 0.0901924391749884 951.6467817930568 0.0104072216328711 0.0842474106715028 809.5091432030971 0.0160350790073878 0.1448895922217034 903.5789106804416 0.0214861161658402 0.1988326577489664 925.4006457671552 0.0226985092267782 0.1988184971628946 875.9099338926688 +r_1899 L-leucine exchange 4.912000000000206e-10 5.546026296505825e-10 112.9077014760911 8.940000000000077e-11 4.126035486246707e-10 461.5252221752428 -4.676343729189922e-11 2.6040531950870576e-10 -556.856669631117 -5.6400000000000046e-11 2.3244321020240187e-10 -412.133351422698 -5.299999999999998e-11 2.387517549256911e-10 -450.475009293757 -7.400000000000044e-11 2.9417904116653247e-10 -397.53924481963605 -8.067802207768806e-11 2.9655664291322215e-10 -367.5804578199204 -7.740000000000052e-11 2.7968711979101037e-10 -361.3528679470394 -5.0199999999999915e-11 2.3851905221104584e-10 -475.1375542052714 +r_1900 L-lysine exchange -1.1691524546855044e-10 4.0459457303063326e-10 -346.05801100547404 1.7531334233423302e-10 5.499495383905864e-10 313.6951991606625 -5.134741817488944e-11 2.3724114295415516e-10 -462.03129852821655 -5.6340615133426045e-11 2.330996895282792e-10 -413.73295086724136 -4.999999999999991e-11 2.389799620981946e-10 -477.9599241963903 -5.880000000000011e-11 3.3070293752335323e-10 -562.4199617744092 -5.800000000000008e-11 2.47079358996114e-10 -425.9988948208856 -1.2320000000000008e-10 3.3112488389994076e-10 -268.770197970731 -1.405684858746862e-10 5.860607936439485e-10 -416.9218939772954 +r_1901 L-malate transport -4.696389631522886e-05 0.0010537370717177 -2243.717311368081 -2.1811466163311672e-05 0.0009654082028238 -4426.149968990639 -4.198472777130554e-05 0.0021094051718603 -5024.220195854258 -0.0001332807529457 0.0047840423585564 -3589.447277885382 -0.0014497504705771 0.0195620272076598 -1349.3375311595298 -7.186463890240811e-05 0.0025484488856618 -3546.179212175098 -0.0013983139986139 0.0212280054884212 -1518.114351244703 -0.0008307740776973 0.0181050026671572 -2179.293162027688 -0.0011923062817134 0.0321433029696303 -2695.893115939788 +r_1902 L-methionine exchange -2.1199999999999958e-10 4.11691508267528e-10 -194.19410767336265 -1.777999999999984e-10 3.8860952571017454e-10 -218.56553751978515 -2.7380000000000416e-10 4.5702881207537216e-10 -166.9206764336615 -1.4999999999999922e-10 3.6705169307479155e-10 -244.70112871652893 -2.736000000000041e-10 4.5429540704630414e-10 -166.0436429262782 -2.9020000000000547e-10 4.57849194797846e-10 -157.77022563674618 -2.8580000000000505e-10 4.6191019928818624e-10 -161.6200837257446 -3.37800000000009e-10 4.801429656398992e-10 -142.1382373119853 -3.3540000000000884e-10 4.805757282740449e-10 -143.28435547824455 +r_1903 L-phenylalanine exchange -3.2195708339758084e-10 5.179923465133381e-10 -160.88863181608454 2.7734347628272374e-11 3.911620550702274e-10 1410.38852008719 -2.52942544181592e-11 3.2487001179240436e-10 -1284.362869218135 -5.6169929667559514e-11 2.908715192466636e-10 -517.8420570724945 -4.3286505738999087e-11 3.2209073747548123e-10 -744.090408723596 -5.50800000000025e-10 5.450493333223824e-10 -98.9559428689829 -1.305225288535194e-11 3.5529644246451874e-10 -2722.1081723236816 -1.8694960645798639e-10 4.730835982073207e-10 -253.0540754647901 -4.639999999999987e-11 2.9977493724892397e-10 -646.0666751054414 +r_1904 L-proline exchange -8.460000000000068e-11 2.9573693050820935e-10 -349.57083984421644 -6.880000000000032e-11 2.586115542414813e-10 -375.8888869788957 -1.477999999999993e-10 3.6821498673367527e-10 -249.1305728915272 -1.7056758145565534e-10 3.793097587149152e-10 -222.3809210858332 -7.940000000000056e-11 2.812675990804194e-10 -354.2413086655131 -5.4e-11 2.4959258661236516e-10 -462.2084937266021 -1.4919999999999926e-10 3.6133844674296836e-10 -242.1839455381838 -2.560000000000029e-10 4.419310586642463e-10 -172.62931979071928 -1.0060000000000076e-10 3.1128607389980073e-10 -309.42949691828863 +r_1905 L-proline transport 0.0001680507053807 0.0024222486204127 1441.379621064055 0.0004968622000998 0.0055607508183232 1119.1736495966668 0.0002805427349524 0.0039228650640811 1398.3128327119011 0.0005099235750886 0.0063807384834838 1251.3127055117031 0.0010119699383173 0.0127639652374202 1261.2988542568055 0.0005062499639358 0.0081084589376008 1601.6710153540278 0.0014673055881888 0.0188477755315674 1284.5160328756945 0.0021254445713791 0.0277662492310807 1306.3737161145286 0.0020585012177548 0.0268991036437994 1306.732462035534 +r_1906 L-serine exchange -7.680000000000049e-11 2.7003026361624434e-10 -351.6019057503158 -1.7159999999999859e-10 3.895944003182467e-10 -227.03636382182395 -5.322000000000237e-10 5.073604664620315e-10 -95.33266938406784 -3.1440000000000726e-10 4.707408622500109e-10 -149.72673735687025 -5.914000000000281e-10 5.00495893317679e-10 -84.6289978555386 -3.0640000000000667e-10 4.6104398088518235e-10 -150.47127313484737 -5.584000000000256e-10 5.010385693033822e-10 -89.72753748269328 -6.688000000000337e-10 4.74079645526011e-10 -70.88511446261766 -6.332433956922241e-10 5.427214576497168e-10 -85.70503243171541 +r_1907 L-serine transport -1.9469628306220782e-10 1.6315599867639483e-09 -838.0026372884813 -2.860679584993173e-10 2.3729727480216482e-09 -829.5136444046427 -2.5970333427871677e-10 1.7655281247457551e-09 -679.8249740032096 -3.565839694956145e-10 2.372366450292009e-09 -665.3037301838621 -3.444606466973953e-10 2.127516978119177e-09 -617.6371665434909 -2.1608373516605822e-10 2.019144946076345e-09 -934.4270842618728 -2.53567309746474e-10 1.7687947082476455e-09 -697.5641734008032 -2.1988151777847176e-10 1.77847019372856e-09 -808.8311431069661 -1.8896275510042327e-10 1.549206181510308e-09 -819.8473718733569 +r_1908 L-sorbitol transport -2.9700000000000595e-10 5.4849901570927e-10 -184.67980326911083 9.939999999999606e-10 1.037600753211294e-10 10.438639368323294 9.733999999999675e-10 2.2249121436157806e-10 22.85712085078955 9.959999999999598e-10 8.237327886768806e-11 8.270409524868613 9.715999999999684e-10 2.2091446453351542e-10 22.73718243449183 -1.5579999999999906e-10 5.38501956237283e-10 -345.6366856465252 9.715999999999684e-10 2.0591726587170536e-10 21.193625552872795 7.994000000000282e-10 5.134319453175037e-10 64.2271635373387 9.763999999999666e-10 2.045761723223412e-10 20.952086472997564 +r_1909 L-sorbose exchange -2.9700000000000595e-10 5.4849901570927e-10 -184.67980326911083 9.939999999999606e-10 1.037600753211294e-10 10.438639368323294 9.733999999999675e-10 2.2249121436157806e-10 22.85712085078955 9.959999999999598e-10 8.237327886768806e-11 8.270409524868613 9.715999999999684e-10 2.2091446453351542e-10 22.73718243449183 -1.5579999999999906e-10 5.38501956237283e-10 -345.6366856465252 9.715999999999684e-10 2.0591726587170536e-10 21.193625552872795 7.994000000000282e-10 5.134319453175037e-10 64.2271635373387 9.763999999999666e-10 2.045761723223412e-10 20.952086472997564 +r_1910 L-sorbose transport 2.9700000000000595e-10 5.4849901570927e-10 184.67980326911083 -9.939999999999606e-10 1.037600753211294e-10 -10.438639368323294 -9.733999999999675e-10 2.2249121436157806e-10 -22.85712085078955 -9.959999999999598e-10 8.237327886768806e-11 -8.270409524868613 -9.715999999999684e-10 2.2091446453351542e-10 -22.73718243449183 1.5579999999999906e-10 5.38501956237283e-10 345.6366856465252 -9.715999999999684e-10 2.0591726587170536e-10 -21.193625552872795 -7.994000000000282e-10 5.134319453175037e-10 -64.2271635373387 -9.763999999999666e-10 2.045761723223412e-10 -20.952086472997564 +r_1911 L-threonine exchange -8.080000000000059e-11 2.7692363087947937e-10 -342.72726593994724 -1.3539999999999968e-10 3.4218453800780277e-10 -252.72122452570432 -2.2840000000000078e-10 4.198436539222173e-10 -183.8194631883607 -6.164000000000297e-10 4.863109495661584e-10 -78.89535197374022 -2.1699999999999995e-10 4.122438465250793e-10 -189.97412282261723 -7.296000000000383e-10 4.4735205909099384e-10 -61.31470108154748 -3.954000000000133e-10 4.889853385657595e-10 -123.66852265193296 -7.924000000000306e-10 4.0562932220121006e-10 -51.18996999005482 -1.2220000000000008e-10 3.2754941264418517e-10 -268.0437092014606 +r_1912 L-tryptophan exchange -5.435950380705676e-10 5.255090766549318e-10 -96.6728979940968 2.166213208975719e-11 4.634609262865816e-10 2139.498200667544 -4.087627188776661e-11 3.794318652087992e-10 -928.244792603885 -4.090519203825701e-12 4.3584856967659046e-10 -10655.091638952788 -5.640692990614632e-11 3.972612235541976e-10 -704.2773365173175 -4.6080000000001825e-10 5.590401284103295e-10 -121.3194723112646 1.701263953790459e-11 4.58207514820541e-10 2693.335821285364 -1.2773421606278488e-10 6.065990251039869e-10 -474.89157079558606 -2.377077560536716e-10 4.949725265348272e-10 -208.2273354274012 +r_1913 L-tyrosine exchange -4.0336834549655336e-10 5.169267206520981e-10 -128.1525252101159 -2.709834846063692e-10 5.98392814496523e-10 -220.82261410349372 -1.677839355350693e-11 4.1812659895122286e-10 -2492.053828739929 1.0541937501819476e-10 5.821957385139235e-10 552.2663537072193 -3.056378104928772e-11 3.7405015028016407e-10 -1223.8346743714856 -5.027301556571499e-10 5.661566836120401e-10 -112.61641603177388 3.678367138350946e-11 4.544946854194313e-10 1235.5881518210456 -5.5994668245479164e-11 5.367203541134856e-10 -958.520464413715 -4.179999999999989e-11 3.2322384616694067e-10 -773.2627898730659 +r_1914 L-valine exchange -5.162000000000225e-10 5.182579263799306e-10 -100.39866841919958 -2.431544239103203e-11 4.2628235993457846e-10 -1753.1342966303548 -1.3008306586475148e-10 4.263897382316655e-10 -327.7826636366232 2.699999999999995e-11 4.1605963649967694e-10 1540.9616166654737 -8.475646339939252e-11 3.6951346434367517e-10 -435.970838710483 -3.2794857145823823e-10 5.031096271982102e-10 -153.41113545977967 -9.869385325326371e-11 4.888234430791358e-10 -495.2926924686374 -1.2962916160709442e-10 5.177539393625828e-10 -399.41162385350697 -7.148088058127486e-11 4.4708212503379904e-10 -625.456935334561 +r_1915 lanosterol exchange 1.2939944689048756e-05 0.0001830214971113 1414.3916493418983 7.2986557447268784e-06 0.0001124274986263 1540.3863746766483 1.2313965902313264e-05 0.0001811626014122 1471.196224266194 2.388654471777037e-05 0.0002989530094091 1251.5540147868944 3.991107762243277e-05 0.000554104619724 1388.3479292791797 3.877590790249854e-05 0.0005501350578277 1418.7548082977023 7.090092773381355e-05 0.0009131308286134 1287.8968693352251 7.072845334495622e-05 0.001120373509267 1584.049213974418 7.967589511649565e-05 0.0011721644038181 1471.1656544357631 +r_1916 laurate exchange 1.2574827435736806e-06 6.344976111514702e-05 5045.775891510615 1.6254535700569364e-06 6.95131539837571e-05 4276.538885163123 4.240431140368198e-06 0.0001340688472077 3161.6796210054745 5.030898843801237e-06 0.0001726165706619 3431.1278366222978 5.0026998290521295e-06 0.0002501564225918 5000.428391467267 9.81135843601756e-06 0.0003477473662534 3544.334543694853 1.128062390920816e-05 0.0004604753229013 4082.002259869914 1.712186439392343e-05 0.0006988872742328 4081.8409616704594 1.0543077279420797e-05 0.0005275653179143 5003.90259819196 +r_1919 lysine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1920 M(IP)2C transport 5.7208558105514555e-11 4.258379542067712e-09 7443.605787465617 -7.439262041931569e-11 4.0106704992991575e-09 -5391.220898918364 -5.899542001133137e-10 5.145256779304563e-09 -872.1451221664836 3.9666176557053545e-11 3.990015249614239e-09 10058.98625967953 -2.55906312164036e-10 4.353811327134638e-09 -1701.3301822519502 7.634453142551877e-11 3.543204283396394e-09 4641.071491614461 3.015590958197736e-12 4.280417072214308e-09 141942.89383240804 1.318299527398251e-10 3.92582637025366e-09 2977.947187769635 -8.548404002341344e-11 3.898312056476043e-09 -4560.280556941769 +r_1921 M(IP)2C transport 8.329210996246324e-11 3.729768406953965e-09 4477.937236353885 -1.3560873092405563e-10 4.198126178454376e-09 -3095.763930425271 1.839996470389828e-10 3.720452817889163e-09 2021.9891058274343 -6.938344179779139e-11 4.566215152331303e-09 -6581.130935589668 -5.855684825388495e-10 5.184536594455905e-09 -885.3851853462654 -1.6857899427269454e-10 4.543992399574233e-09 -2695.467735573176 1.313102115601159e-10 3.547940142370384e-09 2701.95295568927 2.2379471621570088e-10 3.7629648349478654e-09 1681.4359599629654 1.0495704956137904e-10 4.135253498845397e-09 3939.94830850032 +r_1922 M(IP)2C transport -2.5055653320292043e-10 4.110396013763285e-09 -1640.5064203352315 -3.4205348587103187e-10 4.449061452076973e-09 -1300.6917443766238 -2.782900771875829e-10 3.819673857270882e-09 -1372.5512227646589 -2.0927048282140043e-10 4.001506385324135e-09 -1912.1217342147463 8.058986462912309e-11 3.470404324576936e-09 4306.254068731642 -4.0467852079029305e-11 3.3258626072279583e-09 -8218.53010812857 -3.9422329912332367e-11 3.449246124642719e-09 -8749.473032956637 -1.0369463761005192e-10 3.668174620498623e-09 -3537.477641122532 8.330011599409958e-11 3.1699431685715027e-09 3805.448684844616 +r_1923 M(IP)2C transport 6.240312040081683e-12 4.2366438602457676e-09 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1469.9576827451017 1.6798171683773728e-10 4.074011415020097e-09 2425.270732859223 1.3860544924314835e-10 3.755345598606948e-09 2709.378036082218 1.0373130566321335e-10 3.700656526840162e-09 3567.540679431109 2.4618034216534345e-10 3.8199979559847285e-09 1551.7071437893612 2.2000510678139728e-10 3.6875896101011102e-09 1676.1381879036076 +r_1927 M(IP)2C transport -5.488794549444526e-11 3.917895643552832e-09 -7137.989240186314 -2.5279939134407034e-10 4.063431008886303e-09 -1607.3737311162297 3.0968524117737016e-11 3.483467742510895e-09 11248.41380644214 9.257737073257956e-11 3.427442650601878e-09 3702.246697524434 1.9935982882586263e-10 3.565584319680996e-09 1788.516944803094 -9.013566447215779e-11 3.869274337949545e-09 -4292.722931159767 -2.0466982983548688e-11 3.4103306824371833e-09 -16662.595973126074 1.4043702754370032e-10 3.439340383193796e-09 2449.0267583622585 3.2756784847164046e-11 3.369608421883202e-09 10286.74956228169 +r_1928 M(IP)2C transport -2.88847995314074e-10 4.3143527497535256e-09 -1493.6412299010026 -2.846212908663848e-11 3.904069889595146e-09 -13716.71766968378 -1.2938735698606672e-11 3.7183952534256974e-09 -28738.47445408533 1.1685712314863347e-10 3.757435978962985e-09 3215.410304242908 1.778425881708447e-10 3.843332389709703e-09 2161.086626796952 1.9237394806688183e-11 3.8139348041761216e-09 19825.63045828922 -1.6053959932933524e-10 4.1394564659978755e-09 -2578.4644307639537 2.521831449863959e-10 3.5574526781076803e-09 1410.66234949984 -4.064021275416348e-11 3.341099825760187e-09 -8221.167162610142 +r_1929 M(IP)2C transport 6.325588596842948e-10 5.870320866778762e-09 928.0276099063088 1.2917768995356708e-10 5.7073924528226385e-09 4418.249354725385 4.678189232836964e-10 6.048212478385549e-09 1292.853319385238 2.789599925891572e-11 5.592524162078625e-09 20047.76423375916 -2.1907587927796456e-11 6.0926085956318284e-09 -27810.494773372546 3.384002395136772e-10 5.4683379909852e-09 1615.9379788985595 5.444560383622526e-10 5.893977502576311e-09 1082.5442436648602 -9.933244397190363e-10 6.473147697177424e-09 -651.6649986995553 -3.639995144867884e-10 6.876275488676324e-09 -1889.0891924323992 +r_1930 malate/oxaloacetate shuttle 0.0019857627532934 0.0077681730666274 391.19341188889575 0.0041774672085971 0.0151436282368391 362.5074113250656 0.0032452690393576 0.012647450194203 389.71962080242673 0.0050982589054777 0.019121609831678 375.0615687864176 0.0096756599143386 0.0380789856218148 393.5544030995188 0.0079800376096723 0.0292348046214631 366.3492085053395 0.0144702167346958 0.0558202182170603 385.7593790092837 0.0233700292918434 0.0879330880455755 376.2643467300473 0.021204259189586 0.0825595434368077 389.3535855162287 +r_1931 maltose exchange 1.0226507391385254e-10 1.4849962062937346e-09 1452.1049557395188 9.100000000000084e-11 4.189917789434145e-10 460.4305263114404 1.4259999999999946e-10 4.28371264661951e-10 300.40060635480546 9.720000000000084e-11 3.9113010182204216e-10 402.3972240967476 -6.100000000000292e-10 5.712838813187589e-10 -93.65309529815268 1.7299999999999852e-10 4.1797839799234486e-10 241.6060104002014 1.1380000000000036e-10 4.5264836032801037e-10 397.75778587698505 1.639999999999988e-10 4.043967202407513e-10 246.58336600046 1.3979999999999956e-10 3.9885809200203447e-10 285.3062174549612 +r_1932 mannan transport -0.02106930387532 0.0001556718288652 -0.7388560618158949 -0.0334436116833488 0.0002063274008922 -0.6169411451303695 -0.0683715717637394 0.0001926407340028 -0.281755602560235 -0.0903990443398554 0.0002447410834266 -0.2707341490321404 -0.1601433333761583 0.0006742763778263 -0.4210455493907472 -0.1671155367286432 0.0004867447507671 -0.2912624165864025 -0.1813989424858815 0.0008570503273055 -0.4724671023770148 -0.198632441126081 0.0011660468749701 -0.587037479054116 -0.2415558095050534 0.0012161448339514 -0.5034632934075798 +r_1935 methionine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_1936 methylglyoxal synthase 0.0003373410674617 0.0042209827240283 1251.2507758953363 0.0006460696652742 0.0075958308442453 1175.6984196155556 0.0003586052621593 0.0053641453708185 1495.8356546465616 0.000991249201472 0.0105949294686778 1068.8462046621896 0.0011955819706796 0.0168378446892195 1408.3387925002078 0.0012466365640816 0.0161155651076715 1292.7236030127974 0.0020951515129278 0.0276971902585 1321.9659813430237 0.0032367569666399 0.0424148787745182 1310.4128364184455 0.0025095478373784 0.036005942667432 1434.7581716172797 +r_1937 MIPC transport 8.020556543285881e-11 2.983151728606214e-09 3719.382454953767 -3.235608810179733e-10 4.445111668416163e-09 -1373.8099780267455 -2.631244994388885e-11 3.419798914861166e-09 -12996.885208917707 -3.6071414694621877e-10 3.751639507880474e-09 -1040.058877546555 -2.3907254867381815e-10 3.763687847508976e-09 -1574.2869134858358 5.112151482582206e-11 3.396901668010909e-09 6644.759412127388 -6.217859552607782e-11 3.84952925184009e-09 -6191.084277909736 3.7624755176010677e-11 3.2352158563949547e-09 8598.636300117932 -8.843074206983582e-10 5.164922123529655e-09 -584.0640938476796 +r_1938 MIPC transport 6.572942603012188e-11 3.4967786162470113e-09 5319.959152913551 -6.802181519130583e-11 3.8437548677922e-09 -5650.76785584441 7.558111335705299e-11 3.3790317436816903e-09 4470.735602582082 -3.9267470753871405e-11 3.267372034161426e-09 -8320.811021013606 -2.1367437720397887e-10 3.6327113526289603e-09 -1700.1155684479106 5.204354081794072e-12 2.978286990780321e-09 57226.83245552022 1.3816709214080082e-10 3.4354460489650942e-09 2486.4430420697868 -5.7128804221665655e-12 3.1957809406683044e-09 -55939.923550094725 2.205257867378301e-11 3.6901876776274467e-09 16733.588086070355 +r_1939 MIPC transport 1.4577574967935228e-10 2.7272489519430404e-09 1870.8522905503048 -4.717041055240454e-11 2.836584242118903e-09 -6013.482199752248 6.808364349864306e-11 2.551558626511397e-09 3747.6822558156 -1.366653851105262e-11 2.910006475605141e-09 -21292.92997822173 1.7013398208092375e-10 2.673102888443465e-09 1571.1751736769495 -1.1386790905267894e-11 2.7863879258787103e-09 -24470.35296476409 -5.0852365700971055e-11 2.7012495292360827e-09 -5311.944669635105 6.441198577410359e-11 2.7168982991557917e-09 4218.001147618867 1.1136128340713111e-10 2.424293943576656e-09 2176.9630067153253 +r_1940 MIPC transport 9.233622882449015e-11 2.9752207746300524e-09 3222.1597226861627 -9.271402578744743e-11 3.168832170963483e-09 -3417.8562995724333 -7.516592090739976e-11 2.838332945065889e-09 -3776.090162671668 -6.637552748917888e-11 2.888729009573669e-09 -4352.099514455256 1.323691734369011e-10 2.745159501660281e-09 2073.8661656513764 1.253181432644869e-10 3.284863979104245e-09 2621.219795900952 -7.332711720062864e-11 2.946434985310211e-09 -4018.206494124864 5.059713827730414e-11 2.7015891800860314e-09 5339.41102613279 -3.073443770596814e-11 2.718412044815654e-09 -8844.840666428661 +r_1941 MIPC transport -3.1125297151029566e-10 3.919598748250382e-09 -1259.2968122460895 -1.7636643473096788e-10 3.396623255921287e-09 -1925.889844687596 -2.1992160913798176e-10 3.521314620214029e-09 -1601.1680862178068 -9.562931363655544e-11 3.266765748163752e-09 -3416.0715202655097 -3.363499399903029e-10 3.584781043803153e-09 -1065.7891135364864 -2.1164465947751148e-10 3.435614986301976e-09 -1623.293965830983 -3.9301633363934467e-10 3.566673966674608e-09 -907.5129101243924 -1.8034862798270103e-10 2.854680565923789e-09 -1582.867914136618 -1.7565325479894588e-10 3.052512281877069e-09 -1737.805704409519 +r_1942 MIPC transport -3.081192699631677e-10 4.678135358951052e-09 -1518.2871748041823 6.38871877501949e-10 3.6701294751407405e-09 574.4703444282604 1.8998423610707001e-10 3.884469576366275e-09 2044.6273101190843 3.509836558469913e-10 3.141524990271404e-09 895.063042947199 2.909724979248166e-10 3.613821702124034e-09 1241.9805060263109 -1.3781847056328734e-11 3.609736949783143e-09 -26191.967847484728 5.6682815138569046e-11 3.4827807856174472e-09 6144.332770176117 -3.3352030269427694e-11 3.409516727710355e-09 -10222.816122938417 4.2798490177192847e-10 3.29888923923118e-09 770.7957046085578 +r_1943 MIPC transport 6.713794538701282e-11 3.420658450562032e-09 5094.970408825951 2.896306377845421e-10 3.687222427357559e-09 1273.0774808777326 -2.2955293217689083e-10 4.124918490930461e-09 -1796.9356574159754 2.864328487585602e-10 3.0634296237508435e-09 1069.5105805874475 1.2530204292535028e-10 3.337704367022658e-09 2663.727014419967 2.5788151863061208e-11 3.253761669484994e-09 12617.27357106836 2.11241780684796e-10 2.910524385787617e-09 1377.816630948851 1.8472566602125044e-10 3.432654780068807e-09 1858.244635953253 2.5939395000766025e-10 2.7633344971838677e-09 1065.304143408997 +r_1944 MIPC transport 2.6522864617157078e-11 3.035590795157992e-09 11445.184518999253 8.078083487665335e-11 3.071430256728164e-09 3802.1769166139743 1.84396825746292e-11 3.357979591241645e-09 18210.614947688005 3.2121190264404286e-11 3.026071646296637e-09 9420.795497886753 7.505783467827554e-11 2.9567650362595076e-09 3939.315660960977 -3.648417661361182e-11 2.9899384093604515e-09 -8195.164827277315 1.1359811208814938e-10 2.8301998124568643e-09 2491.414479019421 1.706768937632815e-10 2.717495326923002e-09 1592.187007277039 1.6210690885771262e-10 2.409889096494335e-09 1486.6048051101793 +r_1945 MIPC transport 6.220664735719137e-11 3.2248023210482e-09 5184.015628637473 1.978209216583163e-11 3.51982559766088e-09 17792.989579436166 2.126765143795504e-11 3.019611334032943e-09 14198.141919159129 9.644212133238967e-12 3.234340445692603e-09 33536.59584638734 5.883561419222141e-11 3.28337907643145e-09 5580.597944816802 -3.030367282459144e-11 3.512440821258858e-09 -11590.808947780451 -1.663131004461001e-11 3.0274365802264747e-09 -18203.23577701341 1.5694884334654434e-10 2.5283987419471474e-09 1610.969974697056 4.6481342479816354e-11 2.9525953370428027e-09 6352.216135592279 +r_1946 MIPC transport 7.945781417291534e-11 3.9205020101903706e-09 4934.067279598972 -3.2123187504899315e-10 4.825866797537016e-09 -1502.3001054303818 1.7759658520289838e-10 3.766657836137013e-09 2120.906678376573 -1.0352890966950244e-10 3.4227410773857502e-09 -3306.072756211033 -6.357426609590884e-11 4.179901957017924e-09 -6574.833204856943 9.616898281600452e-11 3.411398847942808e-09 3547.2963819006727 7.631591362820498e-11 3.876891339116885e-09 5080.056248824171 -4.455717436637048e-10 3.806691880498967e-09 -854.3387085542091 6.131414802968487e-11 4.554761234632782e-09 7428.564827203701 +r_1947 myo-inositol exchange -5.536000000000253e-10 4.987752954578618e-10 -90.0966935436848 -5.420000000000244e-10 5.002859754295036e-10 -92.3036855035943 -6.770000000000345e-10 4.685241754494587e-10 -69.20593433521933 -4.838000000000201e-10 5.013859168021376e-10 -103.63495593264098 -6.581321662377094e-10 4.858466095881416e-10 -73.82204282242296 -6.86800000000035e-10 4.659926929019014e-10 -67.84983880341842 -4.694000000000189e-10 4.99513305837339e-10 -106.41527606248806 -6.102934080125202e-10 9.92263433388925e-10 -162.5879323554104 -6.687473128061961e-10 4.789192583161553e-10 -71.61438246480805 +r_1952 N,N'-diformyldityrosine exchange 8.228394178414e-06 0.000179639932221 2183.171203589948 3.889066454341255e-06 0.0001374652042437 3534.6581463086777 1.2094555877745574e-05 0.0003230467319769 2671.009462789576 1.902581506259495e-05 0.0004770249573223 2507.251099377032 2.02400513992642e-05 0.0007153790324683 3534.472409958272 1.8457808967426155e-05 0.0005325637142483 2885.302991206508 3.816076271333536e-05 0.0012062663090731 3161.012053492428 0.000103275743367 0.0024323147598469 2355.165579591457 7.759162052979143e-05 0.0020724783142419 2671.007900197501 +r_1963 NADP(+) transport -0.0017022374730564 0.000239898013344 -14.09309906175024 -0.0027496133913104 0.0001955911996161 -7.113407296978834 -0.0063712929337687 0.0002794032837452 -4.385346689436003 -0.0094743362107184 0.0004277003498534 -4.514304119475829 -0.0133898939036452 0.0008429027672578 -6.295066811757005 -0.0158440906317687 0.0008061667614738 -5.08812263328893 -0.0177783603500085 0.0012445534943664 -7.000384005411534 -0.0209033234513306 0.0017571650142834 -8.406151387240897 -0.0236651065729105 0.0016899930078838 -7.141286275965254 +r_1964 NADPH transport 0.0017022374730564 0.000239898013344 14.09309906175024 0.0027496133913104 0.0001955911996161 7.113407296978834 0.0063712929337687 0.0002794032837452 4.385346689436003 0.0094743362107184 0.0004277003498534 4.514304119475831 0.0133898939036452 0.0008429027672578 6.295066811757005 0.0158440906317687 0.0008061667614738 5.08812263328893 0.0177783603500085 0.0012445534943664 7.000384005411534 0.0209033234513306 0.0017571650142834 8.4061513872409 0.0236651065729105 0.0016899930078838 7.141286275965254 +r_1965 NH3 transport -5.543978291377517e-05 0.0011812815252432 -2130.747025255354 -9.737881576110386e-05 0.0019184118546388 -1970.0505080542107 -0.0001032390077645 0.0019083174852433 -1848.4461702655665 -0.0002097086435002 0.0031675271013987 -1510.4418437549732 -0.0002473637460979 0.0050992662717917 -2061.444472858808 -0.0003231097141953 0.0052745159739239 -1632.4225927588316 -0.0004484317125883 0.0083612607179915 -1864.5560702500177 -0.0005864798051928 0.0114632049480069 -1954.577949062961 -0.0004142375905828 0.0093419647950943 -2255.2189872362683 +r_1966 nicotinamide diffusion 1.7912768832584453e-08 1.6209105215198312e-08 90.48911068239174 2.3211936112453e-08 2.8039924253630156e-08 120.79959257938408 1.733513128327254e-09 2.2193428465028557e-09 128.02573053740878 1.918379953638377e-09 2.3664270785043767e-09 123.3554945158929 4.008658882997572e-09 3.556501776153253e-09 88.72048931970467 3.3936856705003943e-09 2.990056987598154e-09 88.10648003111243 4.703558900848674e-09 4.702136653054096e-09 99.9697623050001 7.608620139443418e-09 6.0571965090935975e-09 79.60965849369754 6.9752839559611085e-09 5.163108605369493e-09 74.02004904699368 +r_1967 nicotinate exchange 1.7451440540558378e-08 1.706204287285487e-08 97.7686789420133 1.13731405998202e-08 2.8223762214710106e-08 248.1615519213426 6.327633372762606e-10 5.398689627177e-09 853.1925459549761 -2.011952511706341e-10 6.7208107364421015e-09 -3340.4420319752817 7.730107261889514e-10 8.255572654094962e-09 1067.9764684244503 6.424422439984459e-10 1.3037887583299188e-08 2029.425633992202 8.765666867515825e-10 1.0349907768676833e-08 1180.7325016003 1.277995104967286e-09 1.5904104604422192e-08 1244.457396010863 5.142025322934447e-10 1.5969799200894055e-08 3105.7410646473472 +r_1968 NMN exchange 1.9212397625682748e-10 5.169478150709669e-09 2690.69912638036 -3.5314862631678235e-10 8.634590857191737e-09 -2445.030282928614 1.215134670222603e-09 8.860954537355044e-10 72.92158436835471 1.0392024582080283e-09 9.928878668888998e-10 95.54325618138049 8.87725528467588e-10 9.622402382229578e-10 108.39389060760688 1.3940978124148547e-09 8.692056744312795e-10 62.348973414257244 1.2124818000000282e-09 9.144382867885631e-10 75.41872272132592 1.3390251735508199e-09 8.458343847726038e-10 63.16792256635658 1.5716188860462922e-09 7.392913945121429e-10 47.040119018420015 +r_1970 NMN transport -8.755184442741751e-10 2.090791964485992e-09 -238.8061585863341 -1.409118600079129e-09 2.4728418887075798e-09 -175.48855636202072 -1.3398191463196712e-09 1.2141527445084667e-09 -90.62064442380932 -1.2553999999955283e-09 9.875048724826128e-10 -78.66057611009481 -5.483252843426565e-10 1.6737940242473243e-09 -305.2556706834889 -1.4974929063419767e-09 9.68177574704873e-10 -64.65323278691872 -1.398881800000063e-09 9.64291417267729e-10 -68.93301616102843 -1.550425199999969e-09 1.0219940220770394e-09 -65.91701567267222 -1.6954194000000252e-09 9.032967003645086e-10 -53.27865779785787 +r_1971 NMN transport 0.0 0.0 -1.520176216636544e-16 1.0054774571490284e-14 -6614.216471388371 7.609701433271197e-17 3.804474184095673e-15 4999.505194069403 3.4178749541251005e-16 8.049567668388076e-15 2355.138141807352 3.563034826084772e-17 2.519446087128653e-15 7071.06781186626 0.0 0.0 0.0 0.0 2.6449200565666427e-17 1.870240907694439e-15 7071.067811864941 7.603737267891473e-17 3.801505036492489e-15 4999.521817442612 +r_1972 NMN transport -1.9212397625682748e-10 5.169478150709669e-09 -2690.69912638036 3.5314862631678235e-10 8.634590857191737e-09 2445.030282928614 -1.215134670222603e-09 8.860954537355044e-10 -72.92158436835471 -1.0392024582080283e-09 9.928878668888998e-10 -95.54325618138049 -8.87725528467588e-10 9.622402382229578e-10 -108.39389060760688 -1.3940978124148547e-09 8.692056744312795e-10 -62.348973414257244 -1.2124818000000282e-09 9.144382867885631e-10 -75.41872272132592 -1.3390251735508199e-09 8.458343847726038e-10 -63.16792256635658 -1.5716188860462922e-09 7.392913945121429e-10 -47.040119018420015 +r_1974 nucleoside-diphosphatase (dGDP) 1.4764371662180849e-05 0.0010439988018643 7071.068283512234 0.0001073984139401 0.0037959312719191 3534.438854966102 4.541627137789577e-05 0.0022705864307528 4999.499874967694 3.35454624358786e-05 0.00237202349881 7071.071097452105 0.000200921510371 0.0082009427548451 4081.664894764113 0.0 0.0 0.0001006696569301 0.0071184086274326 7071.056805502561 0.0 0.0 0.0 0.0 +r_1975 nucleoside-triphosphatase (dGTP) 8.818305091290401e-05 0.0025435490183309 2884.39670889044 0.0001344355238914 0.0042478225668759 3159.747099513696 2.308122584430084e-05 0.0016057058877582 6956.761736095932 0.0001067990946307 0.0041287443816267 3865.898298014454 0.0004024636015548 0.0115897194466226 2879.693816247734 0.0001646775258944 0.0067005704329066 4068.9039967735807 0.0006045944205127 0.0174277218000928 2882.547573844849 0.0006117068727921 0.0216014465483293 3531.339520468331 0.001130800340262 0.0283844781652624 2510.122888598064 +r_1976 O-acetylcarnintine transport into mitochondria -5.685476007555285e-10 1.2455596142923356e-08 -2190.774550164565 3.479000700931002e-05 0.0011148243192771 3204.438329026012 6.2389368797124734e-06 0.0004411578312353 7071.0417454269045 3.939814410665874e-05 0.0012987912502478 3296.57977475228 5.4353032033155445e-05 0.0022214492189596 4087.075064376442 2.004704357358772e-05 0.0011347584349956 5660.477719970416 7.701478795981907e-05 0.0031745583110401 4122.011363189588 0.0001146977718809 0.0047492654441713 4140.678032611629 8.231885041116933e-05 0.0041155201641895 4999.4869263032415 +r_1977 O2 transport 0.0008623707873812 0.0002247640820397 26.06350833407369 0.0013810364255164 0.0001556334202509 11.26932044480707 0.0031963656246514 0.0002342654528335 7.329119391936683 0.0047546460055658 0.0003634471539572 7.644042343673033 0.0067337797551653 0.0007395640289394 10.982896023175776 0.0079601039508822 0.0007283954019825 9.150576505998776 0.008948476019576 0.0011285873569046 12.612062148187912 0.010526771919437 0.001545295188588 14.679668187118086 0.0119053699527477 0.0015038730678437 12.631888583157114 +r_1978 O2 transport 0.9617530875515956 0.003604510298105 0.3747854147556038 1.7470439820934451 0.0315569681513152 1.806306451054612 2.7590719413216784 0.007386994725234 0.2677347630774519 4.617028477914713 0.0388849596712409 0.8422074903207742 6.423375359966552 0.0208471192989227 0.3245508495245602 6.728967681939618 0.0128731422030011 0.191309318330542 9.108564065151588 0.0465253357893375 0.5107867217769111 11.019321094488802 0.043158271074885 0.3916599825416671 10.940277717374084 0.0463035973670899 0.4232396888202934 +r_1979 O2 transport 0.9751949685971992 0.0019103308058402 0.1958921925723492 1.7691970235199683 0.0319708312854062 1.8070814533588528 2.807694288049093 0.0057395888983797 0.2044235700022687 4.689362673356913 0.0391931849899087 0.835789161981196 6.526772294264239 0.0155179714942738 0.2377587388472413 6.8499458572314165 0.0053689295818098 0.0783791535540668 9.246277824761757 0.043772273050234 0.4734042593119016 11.183845922016587 0.0283164974759756 0.2531910549682338 11.124715857293522 0.0346150536068442 0.3111544964463081 +r_1980 O2 transport 0.000521966740587 0.0020497658877878 392.7004784792316 0.001102411013389 0.0039635072180305 359.5308074658846 0.0008606684920394 0.0033215841025846 385.93071935442464 0.0013233870678252 0.0048922716828521 369.6780633417998 0.0024909542019809 0.009655657873652 387.62887996789857 0.0021269468163365 0.0077980027057962 366.6289465209771 0.0038387029868924 0.0146062224938197 380.4988962077552 0.0060306509999446 0.0223705460757427 370.9474495530954 0.0055115593357354 0.0212257723419841 385.113740940099 +r_1981 octadecanoate (n-C18:0) transport -7.842643522692254e-06 0.0001606721306913 -2048.6986336489963 -8.196070585699158e-07 4.223121457744437e-05 -5152.617237232086 -1.5572485268670252e-06 7.324676257797988e-05 -4703.601340072707 -3.111410752390056e-06 0.0001270313799485 -4082.758274554693 -6.994951555861512e-06 0.0002183963239411 -3122.1992346491547 -1.283479629324194e-05 0.0003167749884335 -2468.095178108428 -6.742060528740133e-06 0.0003237968484542 -4802.639298089564 -1.078129130830699e-05 0.0004953083909571 -4594.147183236511 -4.712267931572572e-06 0.0003332623432744 -7072.228237310747 +r_1984 octanoate exchange 2.6875547678923527e-05 0.0002886590507967 1074.0583010446846 4.228235555397769e-06 0.0001243465453701 2940.8613531800097 8.624452529959625e-06 0.0001926880123883 2234.2057274828426 1.003886850631909e-05 0.0002508138131441 2498.427118417156 1.014455642757858e-05 0.0003585887478438 3534.78981958286 8.45986939430745e-05 0.0009772322915896 1155.1387451054827 3.0498334055586607e-05 0.000762020512308 2498.564383612473 1.1638713234042496e-05 0.0005819042790854 4999.730360083122 6.149596240086513e-05 0.0013097935770401 2129.8854850049865 +r_1987 ornithine exchange -6.680000000000339e-10 4.722505734467726e-10 -70.69619362975283 -6.524000000000325e-10 4.762558177290693e-10 -73.00058518225711 -2.2500000000000052e-10 4.1858098620027056e-10 -186.03599386678644 -6.188000000000302e-10 4.857301171940676e-10 -78.49549405204328 -7.316000000000384e-10 4.4317120861357203e-10 -60.57561626757089 -4.1800000000001505e-10 4.93684864006359e-10 -118.1064267957754 -2.956000000000059e-10 4.5767076868258816e-10 -154.82772959491854 -5.440000000000245e-10 4.985114870697967e-10 -91.63814100547324 -5.476000000000248e-10 4.977788633111727e-10 -90.90191075806248 +r_1988 oxaloacetate transport 1.1231511636872886e-05 0.0004852512535562 4320.444738383469 0.001620794027089 0.0074639196333199 460.5100653489506 0.0060120960495081 0.0162410968839804 270.1403429060195 0.2594838826047639 0.0996272090941994 38.39437274258298 0.0181814681121715 0.0624798920783559 343.6460229332571 9.84537345055282e-05 0.0026399676952383 2681.429717721994 0.0152240904424635 0.0536288005712561 352.26275601774523 0.0096856717031926 0.0393680303516167 406.45637760610873 0.0815103114835261 0.1792969812987793 219.9684653824648 +r_1989 oxaloacetate(2-) exchange 1.1231511636872886e-05 0.0004852512535562 4320.444738383469 0.001620794027089 0.0074639196333199 460.5100653489506 0.0060120960495081 0.0162410968839804 270.1403429060195 0.2594838826047639 0.0996272090941994 38.39437274258298 0.0181814681121715 0.0624798920783559 343.6460229332571 9.84537345055282e-05 0.0026399676952383 2681.429717721994 0.0152240904424635 0.0536288005712561 352.26275601774523 0.0096856717031926 0.0393680303516167 406.45637760610873 0.0815103114835261 0.1792969812987793 219.9684653824648 +r_1990 oxidized glutathione uniport 7.192876897980096e-10 5.087841652936897e-10 70.73444638494598 8.337447687912743e-10 4.5435308146180765e-10 54.49546413592597 9.338161711752447e-10 1.4847023596252982e-09 158.99300156226056 5.30984789104806e-10 1.6188216779312774e-09 304.8715728110534 6.186722205872087e-10 6.082651353105396e-10 98.3178353689792 7.80958499561942e-10 8.917763024614402e-10 114.18997334194565 8.16789838573192e-10 3.8810519663058445e-10 47.51591882050656 8.388858418715501e-10 3.831050095322852e-10 45.66831270838711 8.647790918802036e-10 3.8687160496385804e-10 44.73646606357252 +r_1991 oxidized thioredoxin transport -3.380048166159065e-05 0.0006715450740156 -1986.7914331491083 -7.0695908405003e-05 0.0012983497706094 -1836.527459512104 -5.700040373303183e-05 0.0010860673141039 -1905.3677570261648 -3.904822450060782e-05 0.001060505117616 -2715.885629062554 -8.100853527509963e-05 0.0021618013421443 -2668.609344438842 -0.0001362210735211 0.0025687141016721 -1885.6950949470977 -0.0001696565850694 0.0038609790526018 -2275.7613864628006 -0.0001893768806827 0.0050067003382005 -2643.7759034523324 -0.0002345934934585 0.0055228399777603 -2354.2170314861787 +r_1992 oxygen exchange -0.9751949685971992 0.0019103308058402 -0.1958921925723492 -1.7691970235199683 0.0319708312854062 -1.8070814533588528 -2.807694288049093 0.0057395888983797 -0.2044235700022687 -4.689362673356913 0.0391931849899087 -0.835789161981196 -6.526772294264239 0.0155179714942738 -0.2377587388472413 -6.8499458572314165 0.0053689295818098 -0.0783791535540668 -9.246277824761757 0.043772273050234 -0.4734042593119016 -11.183845922016587 0.0283164974759756 -0.2531910549682338 -11.124715857293522 0.0346150536068442 -0.3111544964463081 +r_1993 palmitate exchange 4.562682481435388e-06 0.0001288511146439 2824.0210702421973 2.324596749295977e-06 8.219038048610883e-05 3535.683361469074 8.314570761104683e-07 5.884794148568413e-05 7077.68845518437 2.367149854686172e-06 0.0001183839968728 5001.119664583175 1.951117037305336e-05 0.0004875291390674 2498.7180663483846 8.792332544265313e-06 0.0002982113455569 3391.7205025582325 2.492304110946165e-05 0.000658015908189 2640.191079808839 2.368662639513025e-05 0.0007952131452234 3357.224165054525 1.0757677104443864e-05 0.000537874595482 4999.913924353032 +r_1994 palmitoleate exchange 2.795258047429643e-06 9.703156594655466e-05 3471.2918914867005 2.1141633609395955e-06 7.530624208900814e-05 3561.9878520427987 1.5548762331687946e-06 7.776339583013825e-05 5001.259532513312 1.1100077621702506e-06 7.854834607106569e-05 7076.378089238814 4.58675696832426e-06 0.000229349897871 5000.262700965699 1.417834518110378e-05 0.0004088529159853 2883.6434066385923 1.7238013015285356e-05 0.0005449174323286 3161.1383043128103 1.5553759805533687e-05 0.000634879397711 4081.838768560332 4.021412350754449e-05 0.001004667581588 2498.295359836752 +r_1995 palmitoyl-CoA transport -1.9469628306220782e-10 1.6315599867639483e-09 -838.0026372884813 -2.860679584993173e-10 2.3729727480216482e-09 -829.5136444046427 -2.5970333427871677e-10 1.7655281247457551e-09 -679.8249740032096 -3.565839694956145e-10 2.372366450292009e-09 -665.3037301838621 -3.444606466973953e-10 2.127516978119177e-09 -617.6371665434909 -2.1608373516605822e-10 2.019144946076345e-09 -934.4270842618728 -2.53567309746474e-10 1.7687947082476455e-09 -697.5641734008032 -2.1988151777847176e-10 1.77847019372856e-09 -808.8311431069661 -1.8896275510042327e-10 1.549206181510308e-09 -819.8473718733569 +r_1996 panthetheine 4'-phosphate transport -3.535658433304947e-05 0.0008848863267694 -2502.748338001274 -0.0001486544674936 0.002011826976869 -1353.3578982113293 -3.3488355146958515e-05 0.0010656522282995 -3182.1575697675025 -8.555795059543968e-05 0.001798121584566 -2101.6417200879746 -0.0001661588066136 0.0040195753344368 -2419.116636882924 -0.0001285278931877 0.003188149105334 -2480.5114487309106 -0.0003487167915546 0.007104100061845 -2037.211924947151 -0.0006054200752494 0.011572314389782 -1911.4520417933225 -0.0004915125046158 0.010321045458521 -2099.854095591858 +r_1997 panthetheine-phosphate adenylyltransferase 2.134971474948976e-05 0.0005251029880226 2459.5316339542314 4.633000944433224e-05 0.0009124221567688 1969.397735317048 2.6868404333342928e-05 0.0007129715476356 2653.56862577376 7.11128435787169e-05 0.0014544608006586 2045.2856719878969 0.0001057767290311 0.00250309285894 2366.392761305746 6.0742929545794445e-05 0.0017280435903137 2844.847298665401 0.000181062438238 0.0040083986064883 2213.8211798622424 0.0001937305576143 0.0051606827339713 2663.8454963023505 0.0002332445022886 0.0054467037244984 2335.19061373543 +r_1998 PAP uniport -2.9048872737774507e-06 9.3665914236058e-05 -3224.4250949627017 -7.081871596926531e-06 0.0002093677411519 -2956.3899639587994 -4.43812390023655e-06 0.0001811697390901 -4082.124410282853 -8.75056868235233e-06 0.0003093017195008 -3534.6470695625785 -2.353617099570695e-05 0.0006832116285233 -2902.815537191352 -9.92146666162271e-06 0.0003506883950029 -3534.6426789844672 -4.228021862548084e-05 0.0011333394726224 -2680.5430753837827 -5.233624775573602e-05 0.0015244329749262 -2912.7670406198145 -3.338731990144196e-05 0.0011909567936302 -3567.0931274084223 +r_1999 pectin exchange -1.2e-12 3.4623687844479196e-11 -2885.3073203732665 -4.799999999999999e-12 6.912246800510246e-11 -1440.0514167729682 -5.520000000000002e-11 2.2839306617875598e-10 -413.7555546716592 -4.5960000000001804e-10 4.984150113155646e-10 -108.44538975534051 -9.23399999999985e-10 2.659823101596455e-10 -28.80466863327375 -5.818000000000274e-10 4.933127116609755e-10 -84.79077202835205 -5.599999999999999e-12 7.463078420323923e-11 -1332.6925750578437 -3.0820000000000675e-10 4.617958543363034e-10 -149.8364225620679 -1.759999999999999e-11 1.31505508400778e-10 -747.1903886407845 +r_2000 phenethyl acetate exchange 1.779951269305774e-05 0.0004538551748345 2549.817979070566 8.213347859834758e-06 0.0002596221673242 3160.9785894229244 1.7869397047198672e-05 0.0005156500296449 2885.659926201935 2.48434261889528e-05 0.0007168450579602 2885.4516784766565 2.6326196656315315e-05 0.0010231113752172 3886.286304755092 7.194890475863155e-05 0.0017974781558502 2498.270351550553 4.645175490053061e-05 0.0016928001920424 3644.2114957063295 0.0001368689856359 0.0036638344083925 2676.891621113661 8.844872593456675e-05 0.0028456035164653 3217.23516805716 +r_2001 phenylacetaldehyde exchange 1.7936794932806523e-05 0.0004691012335749 2615.301314043275 1.2441592141008735e-05 0.0003590194152162 2885.6388406503606 3.763878590966353e-05 0.0008409391061605 2234.235472363111 2.1140954618136107e-05 0.0007472474787435 3534.596673806238 5.5164790551630935e-05 0.0017437897307156 3161.055653938405 9.77402772138783e-05 0.0023035267875387 2356.7835627252234 0.0001199994680676 0.0031212262887272 2601.0334370537703 7.519532437979286e-05 0.0030692478018927 4081.7003280560193 7.250699859928573e-05 0.0029595239268912 4081.707951045162 +r_2002 phenylacetaldehyde transport 1.793679493280653e-05 0.0004691012335749 2615.301314043274 1.2441592141008735e-05 0.0003590194152162 2885.6388406503606 3.763878590966353e-05 0.0008409391061605 2234.235472363111 2.1140954618136107e-05 0.0007472474787435 3534.596673806237 5.5164790551630935e-05 0.0017437897307156 3161.0556539384047 9.77402772138783e-05 0.0023035267875387 2356.7835627252234 0.0001199994680676 0.0031212262887272 2601.0334370537703 7.519532437979286e-05 0.0030692478018927 4081.7003280560193 7.250699859928573e-05 0.0029595239268912 4081.707951045162 +r_2003 phenylacetaldehyde transport 2.026820198746517e-05 0.0005427500115088 2677.839957606876 1.89355404315836e-06 0.0001338969502703 7071.197717020623 1.372180151670588e-05 0.0004849945798535 3534.481819046317 9.584328672517323e-06 0.0004791732627242 4999.54956780945 6.008283080013696e-05 0.0017336031956606 2885.355387843438 2.0837003386372587e-05 0.0010417131932245 4999.342630552214 6.0417557335762815e-05 0.0021354631604139 3534.5076076915225 9.119857637319492e-05 0.0032234021437558 3534.4873483171027 -3.423630176494415e-11 5.498808923848804e-10 -1606.134027443129 +r_2004 phenylalanine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2005 phosphate exchange -0.0065275352990857 0.0015966377294056 -24.46003975848681 -0.0106510347590095 0.0026241601037252 -24.637607172444216 -0.0243546151938559 0.0030676968462801 -12.59595695461481 -0.0363878291373634 0.0052572990555444 -14.4479601563979 -0.0512234131480468 0.00828407237001 -16.172433387184164 -0.0602455106916545 0.0052405503083586 -8.698656959155917 -0.0680765254525131 0.0125765901041696 -18.474195062940524 -0.08073956289397 0.0203234599670134 -25.17162496123856 -0.0909808575747133 0.0188605466746693 -20.73023620290795 +r_2008 phosphate transport -2.0920684574290864e-10 1.3627716815656402e-09 -651.3991818605837 -7.200632540760244e-10 1.6687767319506575e-09 -231.7541858308003 -3.1406101810891627e-10 8.57404784704341e-10 -273.00579672928194 -4.6123756066784675e-10 1.1489531887449995e-09 -249.10226024987605 -7.827001084765692e-10 9.070655268641111e-10 -115.88928084213556 -1.3630010535582587e-09 1.0286842606622004e-09 -75.4720077417924 -7.26400000000022e-10 9.9867037029328e-10 -137.4821545007227 -0.0006868355248657 0.0222397243296511 -3237.99854907015 -0.0004393531128315 0.0179329815712941 -4081.678505865216 +r_2020 potassium exchange -8.245939132069933e-05 6.092562105366698e-07 -0.7388560608786977 -0.0001343394056084 8.287950669749946e-07 -0.616941144872078 -0.0003119648196452 8.789783573673548e-07 -0.2817556025602411 -0.0004637439538888 1.2555132487608642e-06 -0.2707341493581375 -0.0006538862210835 2.753158831951932e-06 -0.4210455493907674 -0.0007750083096045 2.257307930933882e-06 -0.2912624165391915 -0.0008676552124562 4.099385440915579e-06 -0.472467102377034 -0.0010189775156637 5.981779920081256e-06 -0.5870374790541729 -0.0011553934898627 5.816982115880564e-06 -0.5034632934076398 +r_2022 protoporphyrinogen IX transport 1.3958217504192468e-05 0.0001439643151369 1031.3946970215925 8.005753318949784e-06 0.0001060046104505 1324.1053805592123 1.4419801075164914e-05 0.0001678547888321 1164.057589679841 1.3930017012026926e-05 0.0002030935219423 1457.956022357854 4.532236219298812e-05 0.0005130161546369 1131.9272205020063 3.858790289326032e-05 0.0004661301034462 1207.9695150462333 4.060617428819309e-05 0.0005824694784026 1434.435744349492 9.34694012777442e-05 0.0011187944996471 1196.9633744872604 9.266277582557682e-05 0.0010814233914153 1167.0526614171088 +r_2023 PRPP transport -7.800000000000003e-12 9.022631632528972e-11 -1156.7476451960215 -8.200000000000003e-12 9.019083588356132e-11 -1099.888242482455 -2.439999999999996e-11 1.5430295486599788e-10 -632.3891592868778 -4.1359030627651386e-29 2.9245251020113318e-27 -7071.067811865212 -1.0400000000000007e-11 1.014588526436042e-10 -975.5658908038856 -4e-12 6.312524819271696e-11 -1578.131204817924 -1.52e-11 1.2398400867402596e-10 -815.684267592276 -7.600000000000002e-12 8.685475663284203e-11 -1142.825745168974 -9.800000000000008e-12 9.85185321664741e-11 -1005.2911445558572 +r_2024 putrescine exchange 3.320836161716267e-05 0.0007820973734462 2355.1218288411246 1.0551075749215453e-05 0.0003729217181796 3534.4426202928707 1.1823268255890003e-05 0.0004825856986823 4081.660740818738 2.7954605650056664e-05 0.0008836478096587 3161.009748162601 8.03900825767401e-05 0.0021476249637623 2671.5048609537475 4.7837197854164885e-05 0.0016907923592129 3534.471990536499 0.0001391864662496 0.0034774223013765 2498.391111632927 0.0001591048689306 0.0045906643729746 2885.3072843273376 0.0001519465825092 0.0043842809576686 2885.409388790956 +r_2025 pyridoxal kinase 3.9400000000001327e-10 5.737855400488915e-10 145.6308477281401 4.268000000000157e-10 5.884819642133859e-10 137.88237212121933 3.2960000000000846e-10 5.853480729218261e-10 177.59346872627768 2.5960000000000317e-10 4.926016354766382e-10 189.75409687081364 1.6559999999999874e-10 5.194522173609573e-10 313.6788752179717 1.6519999999999874e-10 5.207333219974655e-10 315.21387530113174 2.8320000000000503e-10 5.66976236195566e-10 200.2034732328941 2.624000000000036e-10 6.05656341435309e-10 230.81415451040425 2.7000000000000403e-10 5.425484971634896e-10 200.94388783832656 +r_2026 pyridoxamine kinase 8.858634422112919e-05 0.0025559844730372 2885.30302893752 0.0001612587391496 0.0046527932858977 2885.296828210102 0.0001815700872501 0.0045360670945192 2498.2458086660176 0.0002348188026772 0.0062720178068814 2671.003231160544 0.0003976446516151 0.0114763326904474 2886.0774673650862 0.0003823965622733 0.0102139074997497 2671.024927376018 0.0005558001668489 0.0162859056980435 2930.172869572135 0.0010694188527299 0.0285642637391095 2671.0080588341457 0.0011803812224835 0.028323027191081 2399.481341416884 +r_2027 pyridoxamine phosphatase 8.858606062112509e-05 0.0025559844713133 2885.312264019856 0.0001612580755496 0.0046527932915689 2885.3087051352286 0.0001815699090501 0.0045360671016536 2498.2482644740503 0.0002348186234772 0.0062720178082425 2671.005270095479 0.0003976445804151 0.011476332692915 2886.077984750445 0.0003823964902733 0.0102139075131628 2671.0254338009504 0.0005558000312489 0.0162859056964889 2930.1735841744835 0.0010694187981299 0.028564263730455 2671.0081943952564 0.0011803810862835 0.0283230271779114 2399.4816171688653 +r_2028 pyridoxine exchange -5.409999999994771e-10 9.76375779057759e-10 -180.4761144285956 -4.9399999999894637e-11 4.0421815701856645e-10 -818.2553785818392 -7.06199999998434e-10 1.009398502605707e-09 -142.93380099234568 -2.723999999987379e-10 7.347831117002041e-10 -269.7441672920737 -3.22399999998844e-10 7.70049891477347e-10 -238.8492219231105 -4.4280000001560307e-10 8.480990593183793e-10 -191.5309528655137 -5.828000000041856e-10 1.0149631471333919e-09 -174.1529078802509 -5.936000000144518e-10 9.392632661545302e-10 -158.23168229980843 -6.568000000044008e-10 1.0162776805906243e-09 -154.73168096586707 +r_2029 pyridoxine kinase -1.3659999999905342e-10 7.985411533486401e-10 -584.5835676092048 -1.0409999999987535e-09 9.122968031785883e-10 -87.6365805167801 1.9839999999999742e-10 6.82884108865638e-10 344.1956193879269 -1.6639999999979107e-10 7.166685166461202e-10 -430.6902143311419 8.560000000063276e-11 5.36591302615486e-10 626.8589983779432 2.055999999999992e-10 5.06931983610436e-10 246.56224883776167 1.6399999999999814e-10 6.134975760792836e-10 374.0838878532261 2.7660000000000497e-10 5.32305466646708e-10 192.44593877320992 2.5060000000000263e-10 4.790047276445297e-10 191.14314750380072 +r_2030 pyrimidine phosphatase 2.271524373492777e-05 1.6789948919537965e-07 0.7391489660188474 3.700710460573424e-05 2.2842819800148698e-07 0.6172549850497953 8.593981847370838e-05 2.4215496332014535e-07 0.2817727191199827 0.000127752127615 3.458947445841955e-07 0.2707545862770719 0.0001801328257654 7.585244344111533e-07 0.4210917311644894 0.0002135013600163 6.215664813219208e-07 0.291129986841446 0.000239022656492 1.1292799168216475e-06 0.4724572696978624 0.0002807095357251 1.6477928317304747e-06 0.5870099237895662 0.0003182893608867 1.6024667769665324e-06 0.5034622497284283 +r_2031 pyrimidine-nucleoside phosphorylase (uracil) -0.0001915506551802 0.0039760326098247 -2075.7081755124373 -0.0003082223782724 0.0069512118745056 -2255.2586588510435 -1.5287440584571753e-05 0.0032910066193476 -21527.51862642731 -0.0002249802792635 0.0085824677484857 -3814.76446583629 -0.0005167772506599 0.0163867864749538 -3170.957400703433 -0.0005108662033196 0.0130163833365843 -2547.904569142368 -0.0008409413891038 0.0259983100124964 -3091.572177247711 -0.000986335471761 0.0355689938891125 -3606.1760838436 -0.0006501577307212 0.0286295557312571 -4403.478475830042 +r_2032 pyrophosphate transport 0.2044796680080286 0.0209144515925611 10.228132604235254 0.3365895236659499 0.037107534097514 11.024565973818495 0.7781170616962525 0.0372998659294295 4.793605970818569 1.1929588715778403 0.0537277267754953 4.503736721822903 1.5948793618065629 0.1080516884525384 6.774912952045814 1.942720976031365 0.0829315375163181 4.26883420416516 2.2252950837554257 0.1650458989806451 7.41680958114159 2.6840031083896343 0.237815323666563 8.860471246221806 2.972869306025487 0.2320874518193342 7.806850148068518 +r_2033 pyruvate exchange 5.022000000000214e-10 5.89630980307682e-10 117.40959384859757 2.898000000000054e-10 4.811052405144657e-10 166.0128504190672 8.200000000000003e-12 1.0832869897402208e-10 1321.0816948051472 6.420000000000023e-11 2.801679118167685e-10 436.398616537021 9.600000000000006e-12 1.229262468817549e-10 1280.4817383516126 1.3499999999999971e-10 5.542891369037205e-10 410.5845458546089 9.44000000000009e-11 2.9716376168749005e-10 314.7921204316603 4.299999999999988e-11 2.1061783394193427e-10 489.8089161440346 1.979999999999998e-11 1.3932638791152578e-10 703.6686258157875 +r_2034 pyruvate transport 0.3564147769027296 0.0533770749425024 14.976111654615767 0.6486333120723017 0.1132892178426456 17.46583404430785 1.125270783180622 0.1397005146588331 12.414835322033705 1.822039757469048 0.2444888905838174 13.418416891376244 2.642036863009963 0.4184240712233192 15.837177636750535 2.659497083241304 0.3178433640872425 11.951258231870892 3.696958246082648 0.5158528060557717 13.953438792617607 4.261427712426525 0.8039098351629295 18.86480047094757 4.68634087212666 0.6940355108877413 14.809753063754156 +r_2036 quinolinate transport -1.0062240576931394e-09 6.161606659722384e-09 -612.3493681763512 -1.3086945804414035e-09 1.39191544386746e-08 -1063.5907450598495 -8.965560126685024e-10 6.469616059311465e-10 -72.16075702906 -5.537031310877224e-10 6.168265698436297e-10 -111.40023149804205 -9.012197978000112e-10 3.630622503341032e-10 -40.2856496517701 -8.96297598281955e-10 3.7169057527219527e-10 -41.4695493979523 -8.50964195487931e-10 4.67145406536104e-10 -54.89601196067353 -9.185363422239383e-10 4.1183602875324447e-10 -44.83611696365946 -8.80530167449288e-10 6.05909879274587e-10 -68.81193872434622 +r_2037 reduced thioredoxin transport 3.3800481461590656e-05 0.0006715450740257 1986.7914449349653 7.069590820500298e-05 0.0012983497706204 1836.527464723228 5.700040333303183e-05 0.0010860673141248 1905.3677704338484 3.904822450060782e-05 0.001060505117616 2715.885629062554 8.100853527509982e-05 0.0021618013421443 2668.609344438836 0.0001362210719211 0.0025687141017571 1885.6951171581063 0.0001696565848694 0.0038609790526107 2275.76138915084 0.0001893768790827 0.0050067003382614 2643.775925821132 0.0002345934868585 0.005522839978041 2354.217097838849 +r_2038 riboflavin exchange 6.084689545861712e-10 5.170892133562006e-10 84.98202076848447 3.650344532458148e-10 5.250207449064571e-10 143.8277237225351 6.187034000000307e-10 5.04985255477901e-10 81.6199257152742 7.10600000000037e-10 4.821764602588633e-10 67.85483538683343 3.7567732530478557e-10 6.476747006266306e-10 172.40186111876056 3.891695978071492e-10 7.763380801743995e-10 199.48579862065932 7.032000000000363e-10 4.91078396590945e-10 69.83481180189412 6.813192516055832e-10 1.0162349742131972e-09 149.15694394637447 6.290008000000867e-10 5.151802369410015e-10 81.90454399118899 +r_2039 riboflavin transport 2.287029355850858e-09 2.7140586571019663e-08 1186.7178924304792 2.5705536745057248e-09 3.393263793376389e-08 1320.0517176630665 7.95681361244052e-09 9.01595907411666e-08 1133.1117597149891 9.888210866216842e-09 1.196707348014878e-07 1210.2364767558088 1.8176140304139973e-08 1.969069800326824e-07 1083.3266949850345 1.9959787421283493e-08 2.201257841797888e-07 1102.846335653177 1.6203073999159968e-08 2.3369561461646455e-07 1442.291843069903 2.6447369338843983e-08 3.2200168177323045e-07 1217.5187545034871 3.5354371220381875e-08 3.719410148419338e-07 1052.036854292883 +r_2040 riboflavin transport 9.083024541385927e-11 3.776708886044763e-10 415.7985997765999 1.2426374675420612e-10 4.2059239587024127e-10 338.4674990543893 7.29640000000045e-12 6.026335533198976e-10 8259.327247955984 -4.990019999999752e-11 4.308095746590021e-10 -863.342380709944 -1.1767732530477387e-10 6.672117770967098e-10 -566.9841453047052 -1.5056959780713727e-10 8.11476275308532e-10 -538.9376654561713 -9.17999999999998e-11 5.240493159399217e-10 -570.8598212853192 -1.709192516055495e-10 1.0894696402230555e-09 -637.4177455078923 -1.1740080000005614e-10 5.452299589172469e-10 -464.4175839661961 +r_2041 ribose transporter 4.728000000000192e-10 5.048872569479689e-10 106.78664487054743 6.096000000000292e-10 4.899345335546598e-10 80.3698381815348 5.952000000000282e-10 4.933412988261263e-10 82.88664294793392 5.546000000000254e-10 5.002688215137651e-10 90.203537957761 5.11000000000022e-10 5.043112788479063e-10 98.69105261211048 8.43000000000013e-10 3.6657587969628734e-10 43.484683237993096 7.092000000000367e-10 4.607361669796469e-10 64.96561858144712 6.192000000000302e-10 4.868662729677977e-10 78.62827405810306 8.344000000000161e-10 3.760384567889192e-10 45.06692914536337 +r_2042 S-adenosyl-L-homocysteine transport 8.970362794010759e-10 7.023094412330939e-10 78.29220036696897 9.951999999662831e-10 9.580603195430316e-11 9.626811892840538 7.92399999968335e-10 4.080876708456889e-10 51.50021086092836 9.963999999457283e-10 7.738370401264819e-11 7.766329186758641 9.88199999960421e-10 1.219169091848832e-10 12.33727071339467 6.837999999982838e-10 4.819377685982586e-10 70.47934609527175 7.313999999659323e-10 4.508821341786212e-10 61.6464498495519 6.10400000004767e-10 4.917928548139833e-10 80.56894738042969 8.91399999964657e-10 3.15635810999581e-10 35.40899831861067 +r_2043 S-adenosyl-L-methionine exchange -4.43800000000017e-10 4.972836395897614e-10 -112.05129328295229 -2.7960000000000465e-10 4.4929301446000646e-10 -160.69134994992814 -4.2900000000001584e-10 4.961937541407777e-10 -115.6628797530908 -2.646000000000034e-10 4.4207004556410176e-10 -167.07106786247016 -3.5720000000001046e-10 4.808891877368287e-10 -134.6274321771597 -3.685009934445253e-10 7.436996426515996e-10 -201.81754076154408 -4.3640000000001645e-10 4.971966219678081e-10 -113.93139825109752 -5.520000000000251e-10 4.977404435143183e-10 -90.17037020186515 -4.36704999777637e-10 7.938320075951701e-10 -181.7776320397926 +r_2044 S-methyl-L-methionine exchange 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2045 serine transport 4.314561390055937e-06 3.116430246675805e-08 0.7223052275622857 7.030197281913983e-06 4.309647880535063e-08 0.6130194797836104 1.6327603715617497e-05 4.5747896773372726e-08 0.2801874516933214 2.427232206159556e-05 6.579710648065181e-08 0.2710787468692915 3.422407747610143e-05 1.4387395899918422e-07 0.4203881290873391 4.056400216767678e-05 1.1842347139034885e-07 0.2919422765555268 4.54135631021913e-05 2.143804144113621e-07 0.4720625288285687 5.333341737548827e-05 3.128689255311628e-07 0.5866283109676665 6.047393405798335e-05 3.0423285281545295e-07 0.5030809679485211 +r_2046 sn-glycero-3-phosphocholine exchange 6.10203193415613e-07 4.320433204201942e-05 7080.318901673249 8.925773712090758e-07 6.31702984689497e-05 7077.291056951162 7.86931203187526e-06 0.0002102359401692 2671.592374500417 4.785756435376848e-06 0.0001955292144848 4085.6490948730025 3.3339906450243205e-06 0.0002357963449231 7072.495697464006 5.299344740109753e-06 0.0002649765326887 5000.175411936398 -6.030785830650418e-10 1.2845317256967126e-09 -212.99574578959576 7.588666846131956e-06 0.0005366372849017 7071.562051445638 1.4594204131379051e-05 0.0007296621892578 4999.670983695767 +r_2049 sodium exchange -9.018286048019826e-05 6.66321530531807e-07 -0.7388560608787891 -0.0001469221598527 9.064232550662772e-07 -0.6169411448720069 -0.0003411846650114 9.613069087461188e-07 -0.2817556025602191 -0.0005071800267049 1.3731095310139006e-06 -0.2707341493581147 -0.0007151317624523 3.011030458085086e-06 -0.4210455493907267 -0.0008475986195949 2.468736221985461e-06 -0.291262416539237 -0.0009489231937883 4.483349917475263e-06 -0.4724671023770131 -0.0011144189358637 6.5420568271964615e-06 -0.5870374790541475 -0.0012636121638444 6.361823415990018e-06 -0.5034632934075743 +r_2050 spermidine acetyltransferase -2.642000000000035e-10 4.409503911433593e-10 -166.9002237484306 -2.1659999999999998e-10 4.1196891105606757e-10 -190.1980198781476 -1.6839999999999866e-10 3.7425853883483666e-10 -222.2437879066744 -2.43800000000002e-10 4.294163942933967e-10 -176.1346982335493 -8.420000000000068e-11 2.777152951441893e-10 -329.8281415014099 -2.3680000000000145e-10 4.2516104287961655e-10 -179.54435932416132 -1.1080000000000043e-10 3.13915703037819e-10 -283.317421514276 -1.0380000000000068e-10 3.0568652055622655e-10 -294.49568454356904 -3.850000000000126e-10 4.86643981235644e-10 -126.40103408717611 +r_2051 spermidine exchange 8.411853316144437e-06 0.0002246794373867 2670.9861542104745 3.562894498453716e-06 0.0001454255825299 4081.6696254421513 5.812464005115848e-06 0.0002054398690656 3534.471248076587 4.184831792016085e-06 0.0002092198452308 4999.4804003838 1.285714501030948e-05 0.0005247855486363 4081.664694732477 2.647637818297192e-05 0.000763921194188 2885.29340723572 1.9325759950331785e-05 0.0007888130128087 4081.6662052932834 4.888619540749285e-05 0.0015452980063601 3161.0109837331743 4.6962130985271697e-05 0.0014844775321269 3161.00973482772 +r_2052 spermine exchange 7.090749414545318e-07 5.015648933928237e-05 7073.510345238815 2.298758086773543e-06 9.382763916857983e-05 4081.666518475333 2.6723275035609617e-06 0.0001090755384165 4081.668069173714 2.57410730339969e-06 0.0001286921922905 4999.488254454929 1.0498675094003998e-05 0.0003710733320378 3534.4777194772723 8.094043311949973e-06 0.0003303787846105 4081.752121622056 6.432046949728908e-06 0.0003173244375601 4933.490691847572 5.993545204279327e-06 0.0004238089978244 7071.090371052158 5.757622903560689e-06 0.0004071280596131 7071.113659794545 +r_2053 squalene transport 0.0008623714982153 0.0002247639967072 26.06347695539381 0.0013810362374761 0.000155633381479 11.269319171773128 0.0031963661344262 0.0002342655626035 7.329121657260243 0.004754646929789 0.0003634469323279 7.6440361964819346 0.006733780410235 0.0007395641616941 10.982896926220644 0.007960104381558 0.0007283952474033 9.150574068989227 0.0089484762345486 0.0011285873942459 12.612062262496664 0.0105267723796886 0.0015452951657406 14.679667328252362 0.0119053702382837 0.0015038728646872 12.63188657376864 +r_2054 squalene-2,3-epoxide transport 0.0008623714804604 0.000224763998761 26.06347773015944 0.00138103621801 0.0001556333837369 11.26931949410874 0.0031963661048037 0.0002342655662669 7.329121839793739 0.0047546468706592 0.0003634469398359 7.644036449451798 0.0067337803677773 0.000739564167261 10.982897078141423 0.0079601043498033 0.0007283952514121 9.15057415585503 0.0089484761904713 0.0011285873998419 12.612062387154923 0.0105267723674424 0.0015452951672322 14.679667359499671 0.0119053701075431 0.0015038728803876 12.631886844364349 +r_2055 stearate exchange 7.842643522692254e-06 0.0001606721306913 2048.6986336489963 8.196070585699158e-07 4.223121457744437e-05 5152.617237232086 1.5572485268670252e-06 7.324676257797988e-05 4703.601340072707 3.111410752390056e-06 0.0001270313799485 4082.758274554693 6.994951555861512e-06 0.0002183963239411 3122.1992346491547 1.283479629324194e-05 0.0003167749884335 2468.095178108428 6.742060528740133e-06 0.0003237968484542 4802.639298089564 1.078129130830699e-05 0.0004953083909571 4594.147183236511 4.712267931572573e-06 0.0003332623432744 7072.228237310746 +r_2056 succinate exchange 4.248977716594397e-05 0.0008284249661438 1949.7041909832224 2.579467057189212e-05 0.001052862283954 4081.7047111324655 0.0001982849793545 0.0037635530301504 1898.052511290356 0.0001071212283853 0.0033884446192002 3163.186858734754 0.0004552119660273 0.0083618289192023 1836.9088563678008 0.0001670490583074 0.0032587624045263 1950.781667101193 0.0007614648221463 0.0139035832500317 1825.8996142253368 0.0009777213390179 0.0194641133674388 1990.762867770504 0.0009153484796704 0.0198515970552067 2168.7474766280548 +r_2057 succinate transport -4.248977716594397e-05 0.0008284249661438 -1949.7041909832224 -2.579467057189212e-05 0.001052862283954 -4081.7047111324655 -0.0001982849793545 0.0037635530301504 -1898.052511290356 -0.0001071212283853 0.0033884446192002 -3163.186858734754 -0.0004552119660273 0.0083618289192023 -1836.9088563678008 -0.0001670490583074 0.0032587624045263 -1950.781667101193 -0.0007614648221463 0.0139035832500317 -1825.8996142253368 -0.0009777213390179 0.0194641133674388 -1990.762867770504 -0.0009153484796704 0.0198515970552067 -2168.7474766280548 +r_2058 sucrose exchange -9.273999999999835e-10 2.737594360853615e-10 -29.51902480972248 -8.276000000000186e-10 3.958656109292533e-10 -47.83296410454861 -9.087999999999899e-10 2.9410858534221587e-10 -32.362300323747704 -7.82600000000034e-10 4.1925218482302837e-10 -53.57170774635959 -1.4479999999999939e-10 3.542005810417539e-10 -244.6136609404388 -9.061999999999916e-10 2.9969905556203246e-10 -33.07206527941241 -9.301999999999827e-10 2.6180463772374413e-10 -28.144983629730056 -7.430000000000393e-10 4.374806028335282e-10 -58.88029647826446 -7.664000000000397e-10 4.2973011716041287e-10 -56.07125745829733 +r_2060 sulphate exchange -0.0023890462773145 0.0018657870643909 -78.09756898004736 -0.0037986017141732 0.0014238918661221 -37.484631800417006 -0.0100155725595851 0.0017318703780387 -17.29177605908652 -0.0164673995426846 0.0024475075325894 -14.862744577523234 -0.0186411860887077 0.00398818063085 -21.394457476425995 -0.025413112934277 0.0051641938608405 -20.32098103918291 -0.0292181343731277 0.0070196617644974 -24.025017048841647 -0.0363569292162563 0.0094325601624195 -25.94432578811401 -0.038853716365667 0.0090868038624766 -23.38721932532101 +r_2061 sulphite exchange 3.9038554130763534e-05 0.0008937751936385 2289.4679722121227 5.049742729154427e-05 0.0012501265794267 2475.6242970739386 8.155731586174131e-05 0.001597547261072 1958.8031364106075 0.000100636909556 0.0021434279958494 2129.8626968037106 0.0001396144855777 0.0035280835421289 2527.018258549485 0.0001986299690018 0.0042367159510864 2132.969144775023 0.0002773317309288 0.0061958540859661 2234.094910530236 0.0003377489927222 0.0084378104306156 2498.2488808057265 0.0003244557002952 0.008105710744966 2498.248832610949 +r_2062 taurine exchange 5.4392129962332936e-11 3.9203672722139717e-10 720.7600207840478 9.785999999999658e-10 1.4746657003488356e-10 15.06913652512658 1.6739999999999872e-10 3.7868974264459107e-10 226.21848425602985 9.53770767077359e-10 8.927822390192965e-10 93.60553602990478 1.6748366301326263e-10 4.784807785593696e-10 285.68803067167204 5.4874912974245925e-11 8.773598535759297e-10 1598.8359817312062 1.90599999999998e-10 3.9332248920712254e-10 206.3601727214726 1.1626799949982703e-10 1.5971248137986602e-09 1373.6581180284577 1.6919999999999862e-10 3.7656303581736727e-10 222.5549857076656 +r_2063 tetracosanoyl-CoA transport 0.0001328268868412 0.0024187136497832 1820.951847402525 -9.122605364124702e-10 6.325810140279349e-09 -693.4214391379955 -2.157045358297538e-09 6.6664281970130086e-09 -309.0536863941763 -1.31787820192553e-09 6.035690384342764e-09 -457.9854477844855 -1.489265247349327e-09 5.444637069302602e-09 -365.5921655993286 -1.307022285038727e-09 5.97594319625982e-09 -457.21815646645626 -2.7985376245229312e-09 7.3594899445677905e-09 -262.97627303911514 -1.615241602451433e-09 5.67428706974503e-09 -351.2964909480558 -1.8103828191610007e-09 6.446714555332522e-09 -356.09675959696585 +r_2064 thiamin phosphatase 7.196615793491525e-05 0.0014097104019203 1958.851830321711 7.985768613440455e-05 0.0019591284878082 2453.2747975078105 7.66266700084685e-05 0.0018046561532022 2355.127990036348 0.0001006364158686 0.0025141504426451 2498.25117572477 0.0002985351706695 0.0060901070314745 2039.996499513052 0.000236210864505 0.0048611681251499 2057.978211686216 0.0003774765998513 0.0084329407085813 2234.0300595860185 0.0005156467500674 0.0121441732506988 2355.1342559823725 0.0004952620856636 0.0116640944874902 2355.135760465014 +r_2065 thiaminase 7.194099527987572e-05 0.0014097114871494 1959.5384824260595 7.98504164374737e-05 0.0019591278226931 2453.497314227807 7.662629027843902e-05 0.0018046556712518 2355.1390321705485 0.0001006357653787 0.0025141496766502 2498.266562774324 0.0002985345383105 0.0060901042783816 2039.9998984527588 0.0002362102688146 0.0048611648284649 2057.982005972884 0.0003774760929213 0.0084329394062282 2234.032714751154 0.0005156452240407 0.0121441683541173 2355.140276283824 0.0004952607052135 0.0116640890099667 2355.141218994412 +r_2066 thiamine(1+) diphosphate(1-) exchange -3.7540623989395105e-10 4.879605424950196e-10 -129.98200100053322 -7.33879859725615e-10 4.4881141827537774e-10 -61.155979732592826 -8.704410149128622e-10 3.6758420823401036e-10 -42.22965162904327 -7.811951220664699e-10 4.362818862611353e-10 -55.84800441496015 -2.3286719743506257e-10 6.155325194695944e-10 -264.3277053399684 -6.756047995200345e-10 4.852542737123055e-10 -71.82516673313178 -8.76574390928438e-10 4.640465196026061e-10 -52.93863526073398 -9.238739973599815e-10 5.189769613400479e-10 -56.17399805850709 -9.313541904145812e-10 4.6058746827966327e-10 -49.45352402125751 +r_2067 thiamine(1+) exchange 1.1196393759186026e-09 8.143229236482691e-09 727.3082218818554 1.963556594624663e-09 7.869283397328824e-09 400.76682377637553 1.739112275428582e-09 5.862187024530531e-10 33.707927356707714 1.6714735713370407e-09 6.583242409314843e-10 39.38586001122825 1.1914651762182364e-09 1.1039128812214606e-09 92.65171179617091 1.058472804036854e-09 8.741873916258875e-10 82.58949954045771 1.8489664895449886e-09 1.0487925477863684e-09 56.72317771667485 1.9001444218024756e-09 1.3445081539963887e-09 70.75820861663712 1.922668971555034e-09 1.1155801748294863e-09 58.022477677330855 +r_2068 thiamine(1+) monophosphate exchange -9.616405208822827e-10 4.490503966511137e-10 -46.69628482783986 -8.82999999999999e-10 3.2516479887785957e-10 -36.82500553543147 -8.00400000000028e-10 4.1736636057039366e-10 -52.144722709942414 -7.850142461036517e-10 4.285742175696194e-10 -54.594450953827824 -5.298671980800233e-10 6.49068140311735e-10 -122.49638072778173 -2.9940000000000607e-10 4.684052953416962e-10 -156.44799443610106 -8.036000000000268e-10 4.1792579771353964e-10 -52.00669458854229 -7.898000000000314e-10 4.1910749243845596e-10 -53.06501550246128 -8.569417992800081e-10 4.3651130520338567e-10 -50.93826740277309 +r_2069 thiamine-phosphate kinase 1.89164706933895e-09 9.396586297655984e-09 496.7409856712695 3.0445507830019005e-08 2.424737565539327e-08 79.64188277222813 1.0486946078896369e-07 5.800012180238731e-09 5.530697055752495 1.548910012502349e-07 7.2475173434134625e-09 4.679108072717989 2.1985662087114057e-07 1.193382780771232e-08 5.428004742557567 2.595110618658842e-07 1.1277006600079314e-08 4.345482045735412 2.918657669853758e-07 1.1493343013805008e-08 3.9378866293630432 3.443582503093655e-07 1.743734050677298e-08 5.063720846272037 3.884666610302937e-07 1.7862894248464127e-08 4.598308179417005 +r_2072 threonine transport 3.3470938629015885e-05 0.0009048733215343 2703.4596536527606 3.530273893518234e-05 0.0009163611250559 2595.7224643062505 6.886159247503495e-05 0.0014432787094946 2095.912478378868 0.0001538184268879 0.0026323302121961 1711.3230615172622 9.736397921221498e-05 0.0027827679934667 2858.1083229984383 0.0001489716089114 0.0033592484611988 2254.9588379593933 0.0002574233355447 0.0058528770704473 2273.638890608193 0.000287292725469 0.0071944325299565 2504.216742073569 0.0002253019875587 0.0061200836126623 2716.3913106034734 +r_2073 thymidine exchange 1.2878904220598744e-05 0.0002628799854371 2041.167330188615 2.324007232566876e-05 0.0004388174917221 1888.193313570153 2.1055883102749992e-05 0.000471683798466 2240.15205709653 2.8470482706935418e-05 0.0006722269277518 2361.1363905259223 0.0001064161826837 0.0018801393964209 1766.7795902893126 5.8405019022031645e-05 0.0010664421164095 1825.9425889533463 8.792346908301442e-05 0.0020748410910417 2359.82623602214 0.0002389823473727 0.0042216370902456 1766.505826332194 0.0002302609107524 0.0040682162042482 1766.7854222214405 +r_2074 thymidine kinase (ATP:thymidine) 8.858653007790402e-05 0.0025559834397204 2885.2958090498023 0.0001612589622691 0.0046527948457342 2885.2938033723367 6.812478823687852e-05 0.0027806138500911 4081.647696903832 6.709144065127278e-05 0.0033542133003186 4999.465308478221 0.0003348694716084 0.0105852549446461 3161.009241541781 0.0001641494192253 0.0067000201191398 4081.659350826121 0.0001962136862501 0.0098130386047235 5001.1998613670585 0.0004583738309565 0.0187092792734428 4081.663919251107 0.0002935553477154 0.0146762880565487 4999.496064631145 +r_2075 thymidine transport -1.2878904220598744e-05 0.0002628799854371 -2041.167330188615 -2.324007232566876e-05 0.0004388174917221 -1888.193313570153 -2.1055883102749992e-05 0.000471683798466 -2240.15205709653 -2.8470482706935418e-05 0.0006722269277518 -2361.1363905259223 -0.0001064161826837 0.0018801393964209 -1766.7795902893126 -5.8405019022031645e-05 0.0010664421164095 -1825.9425889533463 -8.792346908301442e-05 0.0020748410910417 -2359.82623602214 -0.0002389823473727 0.0042216370902456 -1766.505826332194 -0.0002302609107524 0.0040682162042482 -1766.7854222214405 +r_2079 trehalose transporter -3.531639191681797e-10 5.539593557832913e-10 -156.85615820779552 -9.179256125556156e-11 1.3785883781311714e-09 -1501.8519575818518 -1.8359999999999816e-10 5.789283821115633e-10 -315.3204695596781 -3.93999999999999e-11 4.559487008903073e-10 -1157.2302053053518 -4.800877052236587e-10 5.63689943173283e-10 -117.41395104269046 1.1257125990116252e-11 6.28397777920468e-10 5582.222127319184 -3.924000000000131e-10 5.835154994236347e-10 -148.7042557144789 -4.716545418369185e-10 8.629845013413577e-10 -182.9696154266541 -4.732000000000191e-10 5.665209168158119e-10 -119.72124193064008 +r_2080 trehalose vacuolar transport 2.766772607232632e-05 0.0008745849454739 3161.0293639156384 4.031423003732902e-05 0.0014249071370418 3534.501677751252 4.836156197748711e-05 0.0014064844729919 2908.269326881264 9.413906415125656e-05 0.0023907858294704 2539.632033763512 0.0001484585058831 0.0042855639443307 2886.708254832938 0.0001026008320326 0.0032432465706684 3161.0334014007176 0.0002230637824434 0.0064397359624581 2886.948249471806 0.0004583729378865 0.0114513146287694 2498.252772419015 0.0003852906980779 0.010291158277162 2671.0113502613603 +r_2082 tryptophan transport 1.2e-12 3.462368784447919e-11 2885.307320373266 6.000000000000003e-13 2.4489996978163342e-11 4081.666163027224 2e-13 1.4142135623730436e-11 7071.067811865217 4.436550847241897e-12 1.0364487393390196e-10 2336.1588202766943 2.2000000000000003e-12 4.6857220572967316e-11 2129.873662407605 0.0 0.0 2.0470867489348786e-12 1.1816545960472707e-10 5772.371867787715 1.5529580121353314e-12 6.144788633010001e-11 3956.828571662965 1.675518063591072e-12 1.7763426412734623e-10 10601.75166041658 +r_2083 tryptophol exchange 2.379830345204434e-05 0.0004088232233233 1717.867091438702 9.640279950552776e-06 0.0002578871528993 2675.100248354826 3.313576243461222e-05 0.0005848921819482 1765.1387473048117 4.117702779752171e-05 0.000777300420299 1887.7040473178447 5.416193606574368e-05 0.001275925346745 2355.760224664618 7.007655748377437e-05 0.0013726399166781 1958.7719002833803 8.24440727015774e-05 0.0019417233261298 2355.2006378411907 0.000111571629513 0.0027873389832662 2498.250671279536 8.016213779136566e-05 0.002312967339468 2885.361347882101 +r_2084 tryptophol transport 2.379830345204434e-05 0.0004088232233233 1717.867091438702 9.640279950552776e-06 0.0002578871528993 2675.100248354826 3.313576243461222e-05 0.0005848921819482 1765.1387473048117 4.117702779752171e-05 0.000777300420299 1887.7040473178447 5.416193606574368e-05 0.001275925346745 2355.760224664618 7.007655748377437e-05 0.0013726399166781 1958.7719002833803 8.24440727015774e-05 0.0019417233261298 2355.2006378411907 0.000111571629513 0.0027873389832662 2498.250671279536 8.016213779136566e-05 0.002312967339468 2885.361347882101 +r_2085 tryptophol transport -5.48925591425648e-06 0.0001947375065712 -3547.6120919310374 -1.193461694841847e-06 8.44179239294684e-05 -7073.36685327426 -1.6582807578981435e-05 0.0004142866666378 -2498.290260347512 -1.7536173698405705e-05 0.0005061652069575 -2886.4062118840634 -3.5849314633662564e-05 0.0010346962973847 -2886.2373185041074 -3.234243073390174e-05 0.0009331796061768 -2885.3106739398017 -4.571020333752961e-05 0.0014449686587275 -3161.151238067708 -6.972007154494036e-05 0.0022038641154828 -3161.018149647633 -3.9990192557578445e-05 0.0016323179147905 -4081.795586356193 +r_2086 tyrosine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2087 tyrosine transport -7.597999999858374e-10 4.3421385091538607e-10 -57.1484405005896 6.759999999579642e-10 1.3713497437715564e-09 202.8623881445017 -7.143999998621776e-10 4.66557794015515e-10 -65.30764195206096 4.189999936170242e-10 1.3029883052448623e-09 310.975733912737 -5.425999981863029e-10 8.83595714436551e-10 -162.8447691467125 -7.333999998953862e-10 5.926168060929857e-10 -80.80403683903977 4.439999998263767e-10 1.362951036022971e-09 306.9709541792667 5.200000040212859e-10 1.2399626962395467e-09 238.454362817426 -2.2140000002278188e-10 5.032223033293017e-10 -227.29101322381248 +r_2089 UMP transport 0.0001070081858515 0.0027985145335986 2615.234069551125 0.0002459948150085 0.0057592553675181 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0.0123368011066397 344.91132258626067 0.0026616384855494 0.0099314857819053 373.1342868622166 0.0041218928718171 0.0148052734714014 359.18627513661335 0.0076484250342315 0.0284243259007807 371.6363273950395 0.0064496657551338 0.0231897173280129 359.54913337259933 0.012394619243149 0.0447476997572501 361.0252068209657 0.0182352917504152 0.0665214566410837 364.79513216216566 0.0172446088149866 0.0636740858896949 369.2405352469247 +r_2099 water diffusion 5.424940230012419e-05 0.0013928691382215 2567.529003390258 8.863485165593292e-05 0.002432158954794 2744.021013579781 0.0001028642191482 0.0023839972035997 2317.615613417497 0.0001142718058743 0.0027816551362384 2434.2444883542457 0.0004597833890393 0.0088990100559978 1935.4788076602413 0.0002996025724042 0.0065410261161729 2183.234297249793 0.0004042717844386 0.0098026955495767 2424.7785591041493 0.0014281390172171 0.0231162627775298 1618.6283337159907 0.0012037381257304 0.0210355350550826 1747.5175543117932 +r_2100 water exchange 1.378418071626498 0.0221450258106807 1.606553647729693 2.31600585323866 0.0312407258533858 1.34890530650859 4.575055414109356 0.0808232872301133 1.7666078312594056 7.028320669427177 0.0369399703665969 0.5255874355204627 9.819011179680912 0.2472122742998047 2.517690119463112 11.076722872890908 0.0837222137774094 0.755839202064995 13.807509343929546 0.2777897150671917 2.0118741776504505 17.29885622331217 0.4237760821526229 2.4497346916008045 18.301576480430047 0.5313314065001775 2.903200208289884 +r_2101 xanthine transport -3.99140098840649e-06 0.0001261965027195 -3161.7094620684347 -1.2039114542160509e-05 0.0003803952424661 -3159.6612951395487 -7.911502606328234e-06 0.0002795069712854 -3532.918905466294 -5.989496525239126e-06 0.0002991990371584 -4995.395454319199 -1.7734487195363933e-05 0.0007236124114263 -4080.2556254095102 -1.5156936008230684e-05 0.0004788693853866 -3159.407581628997 -1.7770852016947593e-05 0.0008881705211551 -4997.906236055165 -7.462294628448124e-05 0.0021906871700924 -2935.674988951759 -6.476117169784907e-05 0.0020469082520225 -3160.702931028813 +r_2102 xanthosine exchange -4.820470875306286e-11 4.611455943806769e-10 -956.6401422379224 -4.579999999999987e-11 3.021930246131203e-10 -659.8100974085614 -6.3324499362016e-11 4.2620247123579437e-10 -673.0451492387856 3.340911397720106e-11 3.822008811063659e-10 1144.0018474215935 -1.775949505286649e-11 4.522191303898032e-10 -2546.351284446076 -5.692103433006104e-11 3.848668511123717e-10 -676.1417034003484 -3.982689888370203e-11 5.068853758631284e-10 -1272.721176065647 -1.1275394787588472e-10 6.525459013472688e-10 -578.7344156371064 2.573803118432933e-11 5.629277223314447e-10 2187.143679716204 +r_2103 xanthosine transport 4.820470875306286e-11 4.611455943806769e-10 956.6401422379224 4.579999999999987e-11 3.021930246131203e-10 659.8100974085614 6.3324499362016e-11 4.2620247123579437e-10 673.0451492387856 -3.340911397720106e-11 3.822008811063659e-10 -1144.0018474215935 1.775949505286649e-11 4.522191303898032e-10 2546.351284446076 5.692103433006104e-11 3.848668511123717e-10 676.1417034003484 3.982689888370203e-11 5.068853758631284e-10 1272.721176065647 1.1275394787588472e-10 6.525459013472688e-10 578.7344156371064 -2.573803118432933e-11 5.629277223314447e-10 -2187.143679716204 +r_2104 xylitol exchange -1.0185999999999592e-09 3.4853742362495644e-10 -34.21730057186042 -1.1077999999999488e-09 3.4957631601717244e-10 -31.55590503856189 -1.0013999999999595e-09 1.3342263795946875e-10 -13.32361074091014 -1.0175999999999567e-09 1.5393173485606593e-10 -15.126939352994546 -1.0651999999999508e-09 2.9760153449648105e-10 -27.938559378191403 -1.038999999999958e-09 3.3331849670256513e-10 -32.08070228128764 -1.0477999999999523e-09 2.6594981831385997e-10 -25.38173490302272 -1.0935999999999523e-09 3.584197719805688e-10 -32.77430248542286 -1.0337999999999542e-09 2.2241279974565023e-10 -21.514103283580976 +r_2105 xylitol transport 1.0185999999999592e-09 3.4853742362495644e-10 34.21730057186042 1.1077999999999488e-09 3.4957631601717244e-10 31.55590503856189 1.0013999999999595e-09 1.3342263795946875e-10 13.32361074091014 1.0175999999999567e-09 1.5393173485606593e-10 15.126939352994546 1.0651999999999508e-09 2.9760153449648105e-10 27.938559378191403 1.038999999999958e-09 3.3331849670256513e-10 32.08070228128764 1.0477999999999523e-09 2.6594981831385997e-10 25.38173490302272 1.0935999999999523e-09 3.584197719805688e-10 32.77430248542286 1.0337999999999542e-09 2.2241279974565023e-10 21.514103283580976 +r_2106 zymosterol exchange 3.7954141070449823e-06 7.165007569420432e-05 1887.806538981048 1.9361641082386588e-06 5.112637981246539e-05 2640.6015685816733 4.4403648435662e-06 8.456895780732763e-05 1904.5497563080328 4.054921316656165e-06 9.390603765238289e-05 2315.853510317216 1.248953163884689e-05 0.0002417881891601 1935.9267917473087 1.5347152504324084e-05 0.0002716507737124 1770.0402314755809 1.3369810929218598e-05 0.000300631474369 2248.5843364627085 3.112164783062131e-05 0.0005875117929017 1887.791405195812 2.5460681968366737e-05 0.0005194468222533 2040.192100505073 +r_2107 zymosterol transport 0.0001290831566094 0.0024239007143074 1877.7823365758245 0.0003188614389044 0.0050643738318537 1588.267885027022 0.0002518732757613 0.0041527013944268 1648.7264803595936 0.0004031885074972 0.0062805202013654 1557.7131005918636 0.000463055945676 0.0097054627664348 2095.9589995685424 0.0004798475443824 0.0089843956648409 1872.3437829412712 0.001097164398827 0.0180584432139509 1645.9195388819624 0.0011600111287129 0.0233410351519481 2012.1388988609367 0.0012521156352739 0.023328178070597 1863.100932007286 +r_2108 lipid pseudoreaction - merge 0.0227160857623202 0.0001678391766621 0.7388560618157782 0.0370081007181382 0.0002283182003614 0.6169411451303478 0.0859407216653628 0.0002421427981728 0.2817556025601961 0.1277531553432387 0.0003458714179802 0.2707341490321219 0.1801339452021157 0.0007584459592154 0.4210455493907324 0.2135009117363308 0.0006218479149572 0.2912624165864283 0.2390234745059068 0.0011293072839988 0.4724671023769677 0.2807100594115241 0.0016478732562208 0.5870374790541679 0.3182902175930254 0.0016024744120882 0.5034632934076538 +r_2111 growth 0.0227160857623202 0.0001678391766621 0.7388560618157782 0.0370081007181382 0.0002283182003614 0.6169411451303478 0.0859407216653628 0.0002421427981728 0.2817556025601961 0.1277531553432387 0.0003458714179802 0.2707341490321219 0.1801339452021157 0.0007584459592154 0.4210455493907324 0.2135009117363308 0.0006218479149572 0.2912624165864283 0.2390234745059068 0.0011293072839988 0.4724671023769677 0.2807100594115241 0.0016478732562208 0.5870374790541678 0.3182902175930254 0.0016024744120882 0.5034632934076538 +r_2112 kynurenine aminotransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2113 spontaneous kynurenic acid to quinaldic acid 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.0001378813695019 1.0104321004530094e-06 0.7328271427116259 0.0002246299569344 1.3719673516600782e-06 0.6107677579533831 0.0005216581405101 1.4691864205957887e-06 0.2816377827745733 0.0007754596616438 2.099357009344359e-06 0.2707242056787257 0.0010934110914475 4.603022832963794e-06 0.4209782458736368 0.0012959484026904 3.774680951223164e-06 0.2912678424069011 0.0014508700434777 6.853486452185516e-06 0.4723708014370139 0.001703907356015 1.00010642601968e-05 0.5869488282265916 0.0019320191408856 9.72605397363874e-06 0.5034139552665151 +r_2115 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.0546376905652432 0.0195324258299974 35.74899602806901 0.0003739885349936 0.0032697057349648 874.27967143974 0.2009945068407975 0.0399789213993079 19.89055423836741 7.302000000000443e-10 1.2522466148155183e-09 171.49364760551117 0.1949490615317982 0.086815132582905 44.53221364635531 0.5003372978089374 0.0744432074223358 14.878604443109744 0.2093660615599483 0.0996827664290277 47.61171208280352 2.5315322551820323 0.2779759530596376 10.98054162614845 9.923999999999611e-10 8.685475663284635e-11 8.751990793314162 +r_2116 acetaldehyde dehydrogenase 4.41876207323013e-05 0.0014836860277472 3357.696122033268 6.120501045014638e-05 0.0022810814033722 3726.952069112498 0.0 0.0 0.0001002489951549 0.004094183293072 4084.014295350864 0.0004401441133313 0.0111190282003464 2526.224448667085 0.0002907566033881 0.0093047686320965 3200.1916804879565 0.0003963488840258 0.0123314028207639 3111.249537404832 0.0001645632602263 0.0082343176815485 5003.740002611374 0.0005744351458323 0.016863822720678 2935.722656078577 +r_2117 phenylalanine transaminase 4.99256916105476e-06 0.0023586635363311 47243.48246851005 1.4000250842448525 37.39397992904103 2670.950710087502 0.0011576037427575 0.0193457456464117 1671.1889338166889 1.1997553129741094 34.623032881297085 2885.841180021034 0.0017205651466836 0.047180106734403 2742.128470133271 2.1992185945077907 46.85610742331504 2130.579813226886 1.7995651130155277 42.39119130862801 2355.6353144451205 2.4010911876129217 48.93443086151968 2038.008015437703 0.0059947975424765 0.1257935991888747 2098.379441466622 +r_2118 tryptophan transaminase 1.272979969135882e-05 0.0002756822260456 2165.644650581165 2.596684534396978e-05 0.0004282953364086 1649.3930268971314 4.364341200322088e-05 0.0006727799224912 1541.5383252839097 6.00471349750635e-05 0.0009481854312738 1579.068562834155 5.624353982099944e-05 0.0011708497366326 2081.749726917917 0.0001009638985213 0.001635329843891 1619.7174117099185 0.0001280291698735 0.0023796944637529 1858.7127184394085 0.0002330930391092 0.0038775005343091 1663.4990684951144 0.0001562506694367 0.0028276622316558 1809.6960748066908 +r_2119 tyrosine transaminase 1.6332187503282942e-05 0.0013804837788931 8452.534472897018 -1.000048500229015 31.61001805286871 -3160.8485034105743 -0.0014393585529628 0.0207868606715399 -1444.1752979999817 -1.7999520330268006 42.39183313524958 -2355.164602023502 -0.0017080014121584 0.0428660982535372 -2509.722647088764 -2.200605017116118 46.856171778976616 -2129.240432269004 -1.5999917376764294 39.97097476244537 -2498.198823232224 -1.199641409038027 34.622615388843975 -2886.080384354796 -0.0034562389922127 0.0994595387206279 -2877.681171490725 +r_2125 coenzyme A: cytoplasm to LP -1.322241362612823e-05 0.0036713352525494 -27765.999131162305 0.0001431025346052 0.0073835514538464 5159.623115143399 0.0001245504692041 0.0075116399077217 6031.000891221679 0.0007996296913064 0.0138603676706801 1733.3483012661773 0.0012328774595674 0.0189952164169223 1540.7221755507403 0.0002225199576738 0.0150585560392572 6767.283346928141 5.39331211769042e-05 0.0374870340919262 69506.51709728842 -0.0039273421569472 0.0555048909426143 -1413.2939969192612 0.0102395179026854 0.0684848003227346 668.8283664680487 +r_2126 sedoheptulose bisphosphatase 0.0001838579425873 0.0036183831809864 1968.0320197575777 0.0003344701769482 0.0061099333098707 1826.7498064005945 0.0001809562983882 0.0044760514215833 2473.553814623208 0.0002683646336092 0.0067044011124006 2498.243163502133 0.0006563450102389 0.0134091171622315 2042.998263573228 0.0004384791484775 0.0109365909347406 2494.210037743614 0.0011167892171054 0.0215036923237871 1925.4924738190089 0.0012120680360782 0.030280845095086 2498.2793204464974 0.0007093652827523 0.0224264766168959 3161.4849446648923 +r_2129 proton leak 0.00017434163916 0.0061644963363211 3535.871502655017 0.0001612583495334 0.0080621014980431 4999.49399294411 0.0002806491415023 0.0096366778893945 3433.710090046883 0.0001005920438387 0.0071128133627067 7070.950237483316 0.0004018430941067 0.0200901454073771 4999.499979471914 0.0008110629202422 0.0256452136618141 3161.926531440308 0.0003020082118437 0.0213552054568723 7071.067811865409 0.0018155808698169 0.064180590922578 3534.989379407111 0.0008806654518092 0.0440288681620831 4999.499874967251 +r_2131 isocitrate dehydrogenase 0.0153073134514081 0.0054274621687496 35.45666054320174 0.0263332762883894 0.0051345485553164 19.49832789162029 0.0708780796006656 0.0121104791510554 17.086353382155842 0.1244663806460856 0.0178097896723177 14.308915853317092 0.1254143631482449 0.0242995996265807 19.375451915230528 0.1873879824178802 0.0351691254480854 18.76807946502 0.2163043278011928 0.0420722262112349 19.450478240039605 0.2601570980849242 0.0530130223264418 20.377311523184577 0.2944962720865252 0.0603159192838549 20.481046791021416 +r_2132 oxoglutarate/malate exchange 0.0245484876227368 0.0209450506711443 85.32114480138108 0.1137031162350596 0.0588590949317317 51.765595245473975 0.1320449035897432 0.0466195557739869 35.30583498991486 0.436713336653846 0.1937182443057268 44.358215801244135 0.2564240421924078 0.1468525154451898 57.26940195997653 0.2746191809148074 0.1005670731264659 36.620556798493965 0.3881486759667569 0.1781174379293716 45.88897217947138 0.491335194738862 0.2330642003342441 47.43486785189785 0.5384387825140053 0.3274662759563546 60.8177357558446 +r_2134 14-demethyllanosterol exchange 3.619199664810946e-06 8.526600213862898e-05 2355.9352905467003 9.530018671220676e-07 3.893565990259845e-05 4085.580652656925 1.382652863341191e-06 5.093475120960133e-05 3683.842312127219 3.145660466073248e-06 9.947722929194102e-05 3162.3638458386845 1.2591288680040908e-05 0.0002703988037483 2147.5069837527326 8.786822905976419e-06 0.000233780919997 2660.5853162014955 1.752256035812504e-05 0.0003938663742893 2247.767256836712 2.8912966845452614e-05 0.0006139474502859 2123.432899735318 1.686077555710634e-05 0.0004465984043099 2648.7417663398846 +r_2136 14-demethyllanosterol transport -3.619199664810946e-06 8.526600213862898e-05 -2355.9352905467003 -9.530018671220676e-07 3.893565990259845e-05 -4085.580652656925 -1.382652863341191e-06 5.093475120960133e-05 -3683.842312127219 -3.145660466073248e-06 9.947722929194102e-05 -3162.3638458386845 -1.2591288680040908e-05 0.0002703988037483 -2147.5069837527326 -8.786822905976419e-06 0.000233780919997 -2660.5853162014955 -1.752256035812504e-05 0.0003938663742893 -2247.767256836712 -2.8912966845452614e-05 0.0006139474502859 -2123.432899735318 -1.686077555710634e-05 0.0004465984043099 -2648.741766339884 +r_2137 ergosta-5,7,22,24(28)-tetraen-3beta-ol exchange 1.175687973562568e-06 3.721692914123179e-05 3165.5447685202657 1.0044515817940304e-06 3.5557177456712606e-05 3539.9593271787835 1.1467220446977956e-06 4.0672889329788746e-05 3546.883006030252 1.5994661904340812e-06 5.671199285334168e-05 3545.68250285744 7.067212217901565e-06 0.0001767780726308 2501.3833910778544 5.9389496608037285e-06 0.0001590421258105 2677.9503934888608 6.869075550306737e-06 0.0002094778853325 3049.5789979081687 1.3173493176665615e-05 0.0003544700928115 2690.782832297032 1.3649839420017446e-05 0.0003650061844602 2674.069439417165 +r_2139 ergosta-5,7,22,24(28)-tetraen-3beta-ol transport -1.175687973562568e-06 3.721692914123179e-05 -3165.5447685202657 -1.0044515817940304e-06 3.5557177456712606e-05 -3539.9593271787835 -1.1467220446977956e-06 4.0672889329788746e-05 -3546.883006030252 -1.5994661904340812e-06 5.671199285334168e-05 -3545.68250285744 -7.067212217901565e-06 0.0001767780726308 -2501.3833910778544 -5.9389496608037285e-06 0.0001590421258105 -2677.9503934888608 -6.869075550306737e-06 0.0002094778853325 -3049.5789979081687 -1.3173493176665615e-05 0.0003544700928115 -2690.782832297032 -1.3649839420017446e-05 0.0003650061844602 -2674.069439417165 +r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 0.0029079157052276 0.0006278162607556 21.589905774331424 0.004767153380127 0.000987606587937 20.716903971542006 0.0107698000690747 0.0013815883877996 12.8283568769942 0.0160020170358787 0.0021784592808202 13.613654303303347 0.0227328751078685 0.003489054661672 15.348057142426 0.0269580283785142 0.0037284321888408 13.830507693256916 0.030160788119716 0.0049862190572079 16.532124549983077 0.0357867362203735 0.0064346710699658 17.980603289278367 0.0402669094035485 0.0066735578689493 16.573305395922098 +r_2141 fatty-acyl-CoA synthase (n-C18:0CoA) 0.0009169079884223 0.0004001934306036 43.645974913167294 0.0014306066747999 0.0006429187446529 44.94028694105427 0.0034081816203244 0.0012343746504023 36.21798330937565 0.0050979761139699 0.0019409307943298 38.0725752914216 0.0071620051297825 0.0026994105117012 37.69070899538973 0.0083600216013316 0.003233964033404 38.68368034944969 0.0095483978291444 0.0038582211403093 40.40700030881577 0.0110839219663991 0.0043921197807285 39.626043868255614 0.0126671876909959 0.0048731576585799 38.47071486944115 +r_2142 B-ketoacyl-ACP synthase (acetoacetyl-ACP) -2.802000000000047e-10 5.408756504908305e-10 -193.0319951787372 9.687999999999692e-10 2.1595343752168477e-10 22.29081725038106 9.63999999999971e-10 2.5281768798220313e-10 26.22590124296792 9.619999999999712e-10 2.5013698987303337e-10 26.00176609906869 9.6539999999997e-10 2.379373086183908e-10 24.64649975330413 -1.2939999999999988e-10 5.233645212320348e-10 -404.4548077527321 9.657999999999703e-10 2.3117319959209077e-10 23.935928721484565 7.672000000000393e-10 5.822988703362372e-10 75.89922710325958 9.649999999999703e-10 2.3871823826314824e-10 24.73764127079332 +r_2143 B-ketoacyl-ACP synthase (3-oxo-hexanoyl-ACP) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2144 B-ketoacyl-ACP synthase (3-oxo-octanoyl-ACP) 2.7260000000000416e-10 5.48406227059825e-10 201.17616546581684 -9.777999999999674e-10 2.3434620463903867e-10 -23.96668077715755 -9.709999999999682e-10 2.8031181734452625e-10 -28.868364299128263 -9.657999999999708e-10 2.7100747039483257e-10 -28.06041316989447 -9.71399999999969e-10 2.588347717904469e-10 -26.64553961194721 1.2779999999999994e-10 5.28699408561164e-10 413.69280795083273 -9.761999999999682e-10 2.600905408081701e-10 -26.64316132023956 -7.77400000000036e-10 5.949117783376034e-10 -76.52582690218367 -9.663999999999703e-10 2.59392553669867e-10 -26.841116894647648 +r_2145 3-oxoacyl-ACP reductase (3-hydroxybutanoyl-ACP) -2.802000000000047e-10 5.408756504908305e-10 -193.0319951787372 9.687999999999692e-10 2.1595343752168477e-10 22.29081725038106 9.63999999999971e-10 2.5281768798220313e-10 26.22590124296792 9.619999999999712e-10 2.5013698987303337e-10 26.00176609906869 9.6539999999997e-10 2.379373086183908e-10 24.64649975330413 -1.2939999999999988e-10 5.233645212320348e-10 -404.4548077527321 9.657999999999703e-10 2.3117319959209077e-10 23.935928721484565 7.672000000000393e-10 5.822988703362372e-10 75.89922710325958 9.649999999999703e-10 2.3871823826314824e-10 24.73764127079332 +r_2146 3-oxoacyl-ACP reductase (3-hydroxyhexanoyl-ACP) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2147 3-oxoacyl-ACP reductase (3-hydroxyoctanoyl-ACP) 2.7260000000000416e-10 5.48406227059825e-10 201.17616546581684 -9.777999999999674e-10 2.3434620463903867e-10 -23.96668077715755 -9.709999999999682e-10 2.8031181734452625e-10 -28.868364299128263 -9.657999999999708e-10 2.7100747039483257e-10 -28.06041316989447 -9.71399999999969e-10 2.588347717904469e-10 -26.64553961194721 1.2779999999999994e-10 5.28699408561164e-10 413.69280795083273 -9.761999999999682e-10 2.600905408081701e-10 -26.64316132023956 -7.77400000000036e-10 5.949117783376034e-10 -76.52582690218367 -9.663999999999703e-10 2.59392553669867e-10 -26.841116894647648 +r_2148 3-hydroxyacyl-thioester dehydratase (trans-but-2-enoyl-ACP) -2.802000000000047e-10 5.408756504908305e-10 -193.0319951787372 9.687999999999692e-10 2.1595343752168477e-10 22.29081725038106 9.63999999999971e-10 2.5281768798220313e-10 26.22590124296792 9.619999999999712e-10 2.5013698987303337e-10 26.00176609906869 9.6539999999997e-10 2.379373086183908e-10 24.64649975330413 -1.2939999999999988e-10 5.233645212320348e-10 -404.4548077527321 9.657999999999703e-10 2.3117319959209077e-10 23.935928721484565 7.672000000000393e-10 5.822988703362372e-10 75.89922710325958 9.649999999999703e-10 2.3871823826314824e-10 24.73764127079332 +r_2149 3-hydroxyacyl-thioester dehydratase (trans-hex-2-enoyl-ACP) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2150 3-hydroxyacyl-thioester dehydratase (trans-oct-2-enoyl-ACP) 2.7260000000000416e-10 5.48406227059825e-10 201.17616546581684 -9.777999999999674e-10 2.3434620463903867e-10 -23.96668077715755 -9.709999999999682e-10 2.8031181734452625e-10 -28.868364299128263 -9.657999999999708e-10 2.7100747039483257e-10 -28.06041316989447 -9.71399999999969e-10 2.588347717904469e-10 -26.64553961194721 1.2779999999999994e-10 5.28699408561164e-10 413.69280795083273 -9.761999999999682e-10 2.600905408081701e-10 -26.64316132023956 -7.77400000000036e-10 5.949117783376034e-10 -76.52582690218367 -9.663999999999703e-10 2.59392553669867e-10 -26.841116894647648 +r_2151 enoyl-ACP reductase (butanoyl-ACP) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2152 enoyl-ACP reductase (hexanoyl-ACP) 2.7260000000000416e-10 5.48406227059825e-10 201.17616546581684 -9.777999999999674e-10 2.3434620463903867e-10 -23.96668077715755 -9.709999999999682e-10 2.8031181734452625e-10 -28.868364299128263 -9.657999999999708e-10 2.7100747039483257e-10 -28.06041316989447 -9.71399999999969e-10 2.588347717904469e-10 -26.64553961194721 1.2779999999999994e-10 5.28699408561164e-10 413.69280795083273 -9.761999999999682e-10 2.600905408081701e-10 -26.64316132023956 -7.77400000000036e-10 5.949117783376034e-10 -76.52582690218367 -9.663999999999703e-10 2.59392553669867e-10 -26.841116894647648 +r_2153 enoyl-ACP reductase (octanoyl-ACP) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2154 elongase I (3-oxotetradecanoyl-CoA) 0.0001440908312393 0.0014646382513652 1016.4687362601238 0.0002163488823937 0.0018153949204031 839.1052915630187 0.0002210368212532 0.0022756335724944 1029.5269175479166 0.0002947850917326 0.0031531244213391 1069.6349679035975 0.0005914066097466 0.0060010179490402 1014.7025498432304 0.000484183658 0.0036507494584484 754.0009659822816 0.0011120982661541 0.0099408373909437 893.8812057787502 0.0022921929752752 0.0180588032432059 787.839568395729 0.0017403190543974 0.0161289487427251 926.781138318894 +r_2155 elongase I (3-oxopalmitoyl-CoA) 0.0001274978320856 0.0012829572947538 1006.2581251512212 0.0002922558444167 0.0026855228753228 918.8944983059022 0.0002582125032336 0.0023125934357481 895.6163651207353 0.0003529754790176 0.0032827005223264 930.0080933276266 0.0006274347318718 0.0060542969437674 964.9285632795336 0.0004841841044404 0.0036507497292162 754.0003266805852 0.000945406209663 0.0087369784875742 924.1507405253574 0.001027429719721 0.0086724350328324 844.0903417887329 0.0013491996831455 0.0125857851296412 932.8333890724286 +r_2156 elongase II (3-oxooctadecanoyl-CoA) 0.0001186728954904 0.0012697049957887 1069.919959854018 0.0004332602048933 0.0027444765289808 633.4476367744317 0.0001608631773886 0.0016466278641114 1023.620129131896 0.0003003679275992 0.0028157444060045 937.4317785891202 0.0004729298183385 0.0051316150140211 1085.0690345660655 0.0008690686800658 0.0061419324311658 706.7257826735303 0.000813129858299 0.0082853902116503 1018.950432958143 0.0017188455788146 0.013318966099561 774.8785733705149 0.001101372857521 0.0114905961788081 1043.2975627046826 +r_2157 elongase II or III (3-oxoicosanoyl-CoA) 8.12283207172191e-05 0.0008099022699935 997.0688336806684 0.000168999024017 0.0014564668846181 861.8197016753006 0.0001566997632368 0.0014467073077534 923.2351586690264 0.000204404664306 0.0019504823501645 954.2259501692778 0.0003378011031287 0.0036261695461484 1073.4629083690756 0.0003068225351192 0.0030031160823301 978.7795023475052 0.0006331421971339 0.0061240556069869 967.2480581311696 0.0008230414977457 0.0085305020891524 1036.4607510698247 0.0007540465447906 0.0078909408556524 1046.4792803796568 +r_2158 elongase II or III (3-oxodocosanoyl-CoA) 5.011728743616459e-05 0.0005460060886172 1089.456585839135 0.0001067131138133 0.0010426151904366 977.0263027472035 8.373283041470468e-05 0.0008962248763956 1070.3386855035742 0.0001244245961641 0.0013029815191966 1047.2057449781614 0.0001757953398632 0.0021559893823015 1226.4200996334264 0.0002108229232429 0.0022087353931837 1047.6732601976069 0.0003180496414029 0.0035927525503282 1129.6200600888944 0.0004573541389136 0.0053528602139963 1170.3972389340545 0.000449528705857 0.0051923590506083 1155.067292245261 +r_2159 elongase II or III (3-oxotetracosanoyl-CoA) 2.916497455148301e-05 0.000378111130436 1296.456233035855 6.31669111571369e-05 0.0007487952184743 1185.4231982495603 3.619533665257868e-05 0.0005178009627032 1430.5736887417304 6.934951192485762e-05 0.0008851864911615 1276.4134405454026 8.78392727935883e-05 0.0013020271177039 1482.2835803337466 0.000105434084869 0.0014101147717214 1337.4372940901153 0.0001591298600616 0.0022843772418011 1435.542795623866 0.0001942052773106 0.0029075156438487 1497.1352396350187 0.0001975952388471 0.0029069829101802 1471.180645414681 +r_2160 elongase III (3-oxohexacosanoyl-CoA) 1.3813122166194824e-05 0.0002438141988966 1765.0911644970154 2.7664832034835657e-05 0.0004623748059344 1671.345068541228 1.7536746840454097e-05 0.0003355518697001 1913.4214159157543 2.316276271194141e-05 0.0004727534641236 2041.0063773607624 8.78393205191804e-05 0.0013020270974562 1482.2827519162151 3.232599488534156e-05 0.0007166372449393 2216.907004660687 8.249004390957042e-05 0.0015569141449121 1887.396431281904 0.0001942046757915 0.0029075156361885 1497.1398728368104 0.0001975939719808 0.0029069832133792 1471.190231279056 +r_2161 B-ketoacyl-CoA reductase ((S)-3-hydroxytetradecanoyl-CoA) 0.0001440908312394 0.0014646382513652 1016.4687362595804 0.0002163488823937 0.0018153949204031 839.105291563019 0.0002210368212533 0.0022756335724943 1029.5269175473777 0.0002947850917326 0.0031531244213391 1069.634967903458 0.0005914066097466 0.0060010179490402 1014.702549843164 0.000484183658 0.0036507494584484 754.0009659822452 0.0011120982661541 0.0099408373909437 893.8812057787655 0.0022921929752752 0.0180588032432059 787.8395683957357 0.0017403190543974 0.0161289487427251 926.781138318894 +r_2162 B-ketoacyl-CoA reductase ((S)-3-hydroxypalmitoyl-CoA) 0.0001274978320856 0.0012829572947538 1006.2581251512212 0.0002922558444167 0.0026855228753228 918.8944983059022 0.0002582125032335 0.0023125934357481 895.6163651208692 0.0003529754790176 0.0032827005223264 930.0080933277276 0.0006274347318718 0.0060542969437674 964.9285632795036 0.0004841841044404 0.0036507497292162 754.0003266805852 0.000945406209663 0.0087369784875742 924.1507405253956 0.001027429719721 0.0086724350328324 844.0903417887329 0.0013491996831456 0.0125857851296412 932.8333890723482 +r_2163 B-ketoacyl-CoA reductase (3-hydroxyoctadecanoyl-CoA) 0.0001186728954904 0.0012697049957887 1069.919959854018 0.0004332602048933 0.0027444765289808 633.4476367744317 0.0001608631773886 0.0016466278641114 1023.620129131896 0.0003003679275992 0.0028157444060045 937.4317785891202 0.0004729298183385 0.0051316150140211 1085.0690345660655 0.0008690686800658 0.0061419324311658 706.7257826735303 0.000813129858299 0.0082853902116503 1018.950432958143 0.0017188455788146 0.013318966099561 774.8785733705149 0.001101372857521 0.0114905961788081 1043.2975627046826 +r_2164 B-ketoacyl-CoA reductase (3-hydroxyicosanoyl-CoA) 8.12283207172191e-05 0.0008099022699935 997.0688336806684 0.000168999024017 0.0014564668846181 861.8197016753006 0.0001566997632368 0.0014467073077534 923.2351586690264 0.000204404664306 0.0019504823501645 954.2259501692778 0.0003378011031287 0.0036261695461484 1073.4629083690756 0.0003068225351192 0.0030031160823301 978.7795023475052 0.0006331421971339 0.0061240556069869 967.2480581311696 0.0008230414977457 0.0085305020891524 1036.4607510698247 0.0007540465447906 0.0078909408556524 1046.4792803796572 +r_2165 B-ketoacyl-CoA reductase (3-hydroxydocosanoyl-CoA) 5.011728743616459e-05 0.0005460060886172 1089.456585839135 0.0001067131138133 0.0010426151904366 977.0263027472035 8.373283041470468e-05 0.0008962248763956 1070.3386855035742 0.0001244245961641 0.0013029815191966 1047.2057449781614 0.0001757953398632 0.0021559893823015 1226.4200996334264 0.0002108229232429 0.0022087353931837 1047.6732601976069 0.0003180496414029 0.0035927525503282 1129.6200600888944 0.0004573541389136 0.0053528602139963 1170.3972389340545 0.000449528705857 0.0051923590506083 1155.067292245261 +r_2166 B-ketoacyl-CoA reductase (3-hydroxytetracosanoyl-CoA) 2.916497455148301e-05 0.000378111130436 1296.456233035855 6.31669111571369e-05 0.0007487952184743 1185.4231982495603 3.619533665257868e-05 0.0005178009627032 1430.5736887417304 6.934951192485762e-05 0.0008851864911615 1276.4134405454026 8.78392727935883e-05 0.0013020271177039 1482.2835803337466 0.000105434084869 0.0014101147717214 1337.4372940901153 0.0001591298600616 0.0022843772418011 1435.542795623866 0.0001942052773106 0.0029075156438487 1497.1352396350187 0.0001975952388471 0.0029069829101802 1471.180645414681 +r_2167 B-ketoacyl-CoA reductase ((S)-3-hydroxyhexacosanoyl-CoA) 1.3813122166194824e-05 0.0002438141988966 1765.0911644970154 2.7664832034911663e-05 0.0004623748059344 1671.3450685366138 1.7536746840454097e-05 0.0003355518697001 1913.4214159157543 2.316276271194141e-05 0.0004727534641236 2041.0063773607628 8.78393205191804e-05 0.0013020270974562 1482.2827519162151 3.232599488534156e-05 0.0007166372449393 2216.907004660687 8.249004390957042e-05 0.0015569141449121 1887.396431281904 0.0001942046757915 0.0029075156361885 1497.139872836811 0.0001975939719808 0.0029069832133792 1471.190231279056 +r_2168 B-hydroxyacyl-CoA dehydratase (trans-tetradec-2-enoyl-CoA) 0.0001440908312394 0.0014646382513652 1016.4687362595804 0.0002163488823937 0.0018153949204031 839.105291563019 0.0002210368212533 0.0022756335724943 1029.5269175473777 0.0002947850917327 0.003153124421339 1069.6349679031782 0.0005914066097466 0.0060010179490402 1014.702549843164 0.000484183658 0.0036507494584484 754.0009659822452 0.0011120982661541 0.0099408373909437 893.8812057787655 0.0022921929752752 0.0180588032432059 787.8395683957357 0.0017403190543974 0.0161289487427251 926.781138318894 +r_2169 B-hydroxyacyl-CoA dehydratase (trans-hexadec-2-enoyl-CoA) 0.0001274978320856 0.0012829572947538 1006.2581251512212 0.0002922558444167 0.0026855228753228 918.8944983059022 0.0002582125032335 0.0023125934357481 895.6163651208692 0.0003529754790176 0.0032827005223264 930.0080933277276 0.0006274347318718 0.0060542969437674 964.9285632795036 0.0004841841044404 0.0036507497292162 754.0003266805852 0.000945406209663 0.0087369784875742 924.1507405253956 0.001027429719721 0.0086724350328324 844.0903417887329 0.0013491996831456 0.0125857851296412 932.833389072348 +r_2170 B-hydroxyacyl-CoA dehydratase (trans-octadec-2-enoyl-CoA) 0.0001186728954904 0.0012697049957887 1069.919959854018 0.0004332602048933 0.0027444765289808 633.4476367744317 0.0001608631773886 0.0016466278641114 1023.620129131896 0.0003003679275992 0.0028157444060045 937.4317785891202 0.0004729298183385 0.0051316150140211 1085.0690345660655 0.0008690686800658 0.0061419324311658 706.7257826735303 0.000813129858299 0.0082853902116503 1018.950432958143 0.0017188455788146 0.013318966099561 774.8785733705149 0.001101372857521 0.0114905961788081 1043.2975627046826 +r_2171 B-hydroxyacyl-CoA dehydratase (trans-icos-2-enoyl-CoA) 8.12283207172191e-05 0.0008099022699935 997.0688336806684 0.000168999024017 0.0014564668846181 861.8197016753006 0.0001566997632368 0.0014467073077534 923.2351586690264 0.000204404664306 0.0019504823501645 954.2259501692778 0.0003378011031287 0.0036261695461484 1073.4629083690756 0.0003068225351192 0.0030031160823301 978.7795023475052 0.0006331421971339 0.0061240556069869 967.2480581311696 0.0008230414977457 0.0085305020891524 1036.4607510698247 0.0007540465447906 0.0078909408556524 1046.4792803796572 +r_2172 B-hydroxyacyl-CoA dehydratase (trans-docos-2-enoyl-CoA) 5.011728743616459e-05 0.0005460060886172 1089.456585839135 0.0001067131138133 0.0010426151904366 977.0263027472035 8.373283041470468e-05 0.0008962248763956 1070.3386855035742 0.0001244245961641 0.0013029815191966 1047.2057449781614 0.0001757953398632 0.0021559893823015 1226.4200996334264 0.0002108229232429 0.0022087353931837 1047.6732601976069 0.0003180496414029 0.0035927525503282 1129.6200600888944 0.0004573541389136 0.0053528602139963 1170.3972389340545 0.000449528705857 0.0051923590506083 1155.067292245261 +r_2173 B-hydroxyacyl-CoA dehydratase (trans-tetracos-2-enoyl-CoA) 2.916497455148305e-05 0.000378111130436 1296.456233035853 6.31669111571369e-05 0.0007487952184743 1185.4231982495603 3.619533665257868e-05 0.0005178009627032 1430.5736887417304 6.934951192485762e-05 0.0008851864911615 1276.4134405454026 8.78392727935883e-05 0.0013020271177039 1482.2835803337466 0.000105434084869 0.0014101147717214 1337.4372940901153 0.0001591298600616 0.0022843772418011 1435.542795623866 0.0001942052773106 0.0029075156438487 1497.1352396350187 0.0001975952388471 0.0029069829101802 1471.1806454146808 +r_2174 B-hydroxyacyl-CoA dehydratase (trans-hexacos-2-enoyl-CoA) 1.3813122166194824e-05 0.0002438141988966 1765.0911644970154 2.766483203494966e-05 0.0004623748059344 1671.345068534314 1.7536746840454097e-05 0.0003355518697001 1913.4214159157543 2.316276271193182e-05 0.0004727534641236 2041.006377361606 8.78393205191804e-05 0.0013020270974562 1482.2827519162151 3.232599488534155e-05 0.0007166372449393 2216.907004660688 8.249004390957042e-05 0.0015569141449121 1887.396431281904 0.0001942046757915 0.0029075156361885 1497.139872836811 0.0001975939719808 0.0029069832133792 1471.190231279056 +r_2175 trans-2-enoyl-CoA reductase (n-C14:0CoA) 0.0001440908203656 0.001464638252435 1016.4688137091462 0.0002163488825936 0.0018153949203793 839.1052907764674 0.00022103683432 0.002275633571225 1029.5268561120777 0.0002947850927974 0.0031531244212394 1069.6349640061908 0.0005914066111466 0.0060010179489023 1014.702547417799 0.0004841836864919 0.003650749454669 754.0009208323194 0.0011120982677541 0.0099408373907645 893.8812044766112 0.0022921929684111 0.0180588032440768 787.8395707929515 0.0017403190549974 0.0161289487426595 926.7811379956066 +r_2176 trans-2-enoyl-CoA reductase (n-C16:0CoA) 0.0001274978396894 0.001282957293998 1006.2580645464474 0.0002922558530594 0.002685522874382 918.8944708099428 0.0002582125035335 0.0023125934357145 895.61636406724 0.0003529754792176 0.003282700522305 930.0080927947226 0.0006274347221505 0.0060542969447749 964.9285783903292 0.0004841840985846 0.003650749729993 754.0003359599566 0.0009454062103978 0.0087369784874946 924.1507397987336 0.0010274297208072 0.008672435032704 844.0903408838659 0.0013491996710354 0.0125857851309389 932.8333975415114 +r_2177 trans-2-enoyl-CoA reductase (n-C18:0CoA) 0.0001186728923152 0.0012697049960856 1069.9199887307043 0.0004332602056932 0.0027444765288545 633.4476355758089 0.0001608631701505 0.0016466278648187 1023.6201756299866 0.0003003679275992 0.0028157444060045 937.4317785891202 0.0004729298183385 0.0051316150140211 1085.0690345660655 0.0008690686855463 0.0061419324303905 706.7257781275591 0.000813129858299 0.0082853902116503 1018.950432958143 0.0017188455644675 0.013318966101413 774.8785799461052 0.0011013728603951 0.0114905961785325 1043.2975599571405 +r_2178 trans-2-enoyl-CoA reductase (n-C20:0CoA) 8.122831282563393e-05 0.0008099022707854 997.06893152387 0.0001689990248169 0.0014564668845252 861.8196975413179 0.0001566997253905 0.0014467073118527 923.2353842657787 0.0002044046665045 0.0019504823499343 954.2259397930476 0.0003378010965311 0.0036261695467632 1073.4629295166906 0.0003068224794519 0.0030031160880185 978.7796817829874 0.0006331421567007 0.0061240556111674 967.2481205610632 0.0008230414516584 0.0085305020935991 1036.4608096482116 0.0007540465110648 0.0078909408588754 1046.4793276123214 +r_2179 trans-2-enoyl-CoA reductase (n-C22:0CoA) 5.011724182439762e-05 0.0005460060928066 1089.457585714244 0.0001067130887561 0.0010426151930013 977.0265345645732 8.373259481209453e-05 0.0008962248984052 1070.3417234548624 0.000124424541024 0.0013029815244623 1047.2062132910642 0.0001757951985134 0.0021559893938269 1226.4210923041842 0.0002108228736551 0.0022087353979173 1047.6735088672267 0.0003180493299521 0.0035927525779023 1129.621174942652 0.0004573539962232 0.0053528602261895 1170.3976067538265 0.0004495285273524 0.0051923590660646 1155.0677543526815 +r_2180 trans-2-enoyl-CoA reductase (n-C24:0CoA) 2.916493935353586e-05 0.0003781111331473 1296.457806971321 6.31668275568908e-05 0.0007487952255251 1185.4247782995503 3.619522569376551e-05 0.0005178009704552 1430.5780956753815 6.934949202898665e-05 0.0008851864927198 1276.4138089863204 8.783923833181295e-05 0.0013020271200288 1482.2841645216442 0.0001054339877225 0.0014101147789848 1337.4385332889776 0.0001591293482976 0.0022843772774513 1435.5474347690829 0.0001942051666805 0.0029075156512386 1497.1360962918377 0.0001975951806807 0.0029069829141339 1471.1810804894317 +r_2181 trans-2-enoyl-CoA reductase (n-C26:0CoA) 1.3813121886889983e-05 0.0002438141989125 1765.0912003028286 2.76648122965864e-05 0.0004623748071137 1671.346265272981 1.7536747444754137e-05 0.0003355518696694 1913.421349805588 2.3162762125285704e-05 0.0004727534641524 2041.0064291786164 8.783932043361313e-05 0.0013020270974619 1482.2827533666507 3.2325981161026665e-05 0.0007166372455583 2216.907947785213 8.248999177985775e-05 0.0015569141476733 1887.397627373193 0.0001942046799994 0.0029075156359075 1497.1398402525654 0.0001975939737808 0.002906983213257 1471.1902178152409 +r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 0.0021424739463189 0.0002677024270449 12.49501435034282 0.003481961868652 0.0003682851116662 10.576942699514824 0.0080360545722256 0.0002839419040323 3.533349624251551 0.0119503228717112 0.0004502304969296 3.767517428298463 0.0168950681892406 0.0010557761161936 6.24901956220605 0.0199936319281541 0.0009352309198938 4.677643978115595 0.0224070407133858 0.0014069775886507 6.27917629395064 0.0263836188508606 0.0023258854258765 8.815642156688716 0.0299077665359409 0.0023555681271838 7.876108449466278 +r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 0.0007442708326024 0.0004696942691094 63.107977437078375 0.0012108743560635 0.0007953906061722 65.68729465524828 0.0027163332241076 0.0007175122635788 26.41473649885413 0.0040481519028335 0.0011101011358293 27.422417994057263 0.0057692231336371 0.0022416119098329 38.85465786135648 0.006773994349647 0.0018850229831312 27.82734802885501 0.0077942955791169 0.0038468057490511 49.35411686667127 0.0091188151192136 0.0049193755100159 53.947529867675456 0.0102744293067083 0.0048921485706688 47.614796156850495 +r_2184 octanoate (n-C8:0) transport -2.6875547678923527e-05 0.0002886590507967 -1074.0583010446846 -4.228235555397769e-06 0.0001243465453701 -2940.8613531800097 -8.624452529959625e-06 0.0001926880123883 -2234.2057274828426 -1.003886850631909e-05 0.0002508138131441 -2498.427118417156 -1.014455642757858e-05 0.0003585887478438 -3534.78981958286 -8.45986939430745e-05 0.0009772322915896 -1155.1387451054827 -3.0498334055586607e-05 0.000762020512308 -2498.564383612473 -1.1638713234042496e-05 0.0005819042790854 -4999.730360083122 -6.149596240086513e-05 0.0013097935770401 -2129.8854850049865 +r_2185 decanoate (n-C10:0) transport -9.366186212654776e-06 0.000171563910156 -1831.737126090964 -4.358186583139713e-06 0.0001231161791249 -2824.9405291915846 -3.4976278754929547e-06 0.0001192991622605 -3410.859202503922 -3.991193279511316e-06 0.0001456949038359 -3650.409630220433 -1.2383588829599773e-05 0.0003917808821791 -3163.710355456349 -5.097427912913444e-05 0.0007698514867298 -1510.274396974866 -2.651291781366068e-05 0.0007081983483097 -2671.144508828356 -2.2489423477085668e-05 0.00079564984919 -3537.8845971786527 -1.107151134962612e-05 0.0005535655800913 -4999.9097919911965 +r_2186 laurate (n-C12:0) transport -1.2574827435736806e-06 6.344976111514702e-05 -5045.775891510615 -1.6254535700569364e-06 6.95131539837571e-05 -4276.538885163123 -4.240431140368198e-06 0.0001340688472077 -3161.6796210054745 -5.030898843801237e-06 0.0001726165706619 -3431.1278366222978 -5.0026998290521295e-06 0.0002501564225918 -5000.428391467265 -9.81135843601756e-06 0.0003477473662534 -3544.334543694853 -1.128062390920816e-05 0.0004604753229013 -4082.002259869914 -1.712186439392343e-05 0.0006988872742328 -4081.8409616704594 -1.0543077279420797e-05 0.0005275653179143 -5003.902598191962 +r_2187 butyrate exchange 2.3419767843822777e-06 7.930420916535433e-05 3386.2081679973485 3.4527139190816e-06 0.0001220347754567 3534.45950972854 4.971627777846386e-06 0.0001434456988261 2885.2863737171388 8.50892758373403e-06 0.000227273354561 2670.998810655032 9.775253910460403e-06 0.0003455027600852 3534.4632809544587 1.649973632202787e-05 0.0004122143487737 2498.308704627446 1.4540099263638914e-05 0.0005139990321345 3535.044863276048 3.8710198811700434e-05 0.0010341008783794 2671.3912873703207 2.6293348795235e-05 0.0008313793431633 3161.937833167922 +r_2188 hexanoate exchange 2.9200998295507835e-06 9.18022708008042e-05 3143.805902516925 7.904056447913829e-06 0.0001765838283271 2234.091184580532 4.92325479733806e-06 0.0001420540929347 2885.369512290328 5.991034538416027e-06 0.0001893766476755 3161.000766415093 1.4425570286372067e-05 0.0004162780951153 2885.6959333431123 4.3052264502646e-06 0.0002152375014638 4999.4466946233415 2.8909168283857305e-05 0.0007223478121956 2498.680712993721 2.209297916206428e-05 0.0007808694823753 3534.468921765882 3.464640354133856e-05 0.0009397102580721 2712.288035758022 +r_2189 oleate exchange 1.848657837364787e-06 7.556224097601535e-05 4087.41084741389 9.96675494054701e-07 4.987613735147536e-05 5004.250395338604 1.2812910868876717e-06 6.42730887962151e-05 5016.275337740627 3.922649427325914e-06 0.000138678656436 3535.331387759958 4.321380254090942e-06 0.0001971973886161 4563.2963780377295 6.261332870625207e-06 0.0002554453004938 4079.727204606269 1.4765118758298495e-05 0.0004676674460835 3167.380186635585 1.824248276690852e-05 0.0006449897058254 3535.646512959564 -1.0669375663741522e-09 4.952708067647945e-09 -464.19848955914784 +r_2190 butyrate (n-C4:0) transport -2.3419767843822777e-06 7.930420916535433e-05 -3386.2081679973485 -3.4527139190816e-06 0.0001220347754567 -3534.45950972854 -4.971627777846385e-06 0.0001434456988261 -2885.2863737171388 -8.50892758373403e-06 0.000227273354561 -2670.998810655032 -9.775253910460403e-06 0.0003455027600852 -3534.4632809544587 -1.649973632202787e-05 0.0004122143487737 -2498.308704627446 -1.4540099263638914e-05 0.0005139990321345 -3535.044863276048 -3.8710198811700434e-05 0.0010341008783794 -2671.3912873703207 -2.6293348795235e-05 0.0008313793431633 -3161.937833167922 +r_2191 hexanoate (n-C6:0) transport -2.9200998295507835e-06 9.18022708008042e-05 -3143.805902516925 -7.904056447913829e-06 0.0001765838283271 -2234.091184580532 -4.92325479733806e-06 0.0001420540929347 -2885.369512290328 -5.991034538416027e-06 0.0001893766476755 -3161.000766415093 -1.4425570286372067e-05 0.0004162780951153 -2885.6959333431123 -4.3052264502646e-06 0.0002152375014638 -4999.4466946233415 -2.8909168283857305e-05 0.0007223478121956 -2498.6807129937206 -2.209297916206428e-05 0.0007808694823753 -3534.468921765882 -3.464640354133856e-05 0.0009397102580721 -2712.288035758022 +r_2192 octadecenoate (n-C18:1) transport -1.848657837364787e-06 7.556224097601535e-05 -4087.41084741389 -9.966754940547011e-07 4.987613735147536e-05 -5004.250395338604 -1.2812910868876717e-06 6.42730887962151e-05 -5016.275337740627 -3.922649427325914e-06 0.000138678656436 -3535.331387759958 -4.321380254090941e-06 0.0001971973886161 -4563.29637803773 -6.261332870625207e-06 0.0002554453004938 -4079.727204606269 -1.4765118758298495e-05 0.0004676674460835 -3167.3801866355843 -1.824248276690852e-05 0.0006449897058254 -3535.646512959564 1.0669375663741522e-09 4.952708067647945e-09 464.19848955914784 +r_2193 myristate exchange 3.0036159145175984e-06 0.0001061737563076 3534.8646208206446 -7.623101563080354e-10 1.1608772119585943e-09 -152.2841067185658 8.393141298142154e-07 5.94086887615517e-05 7078.242418568837 3.601985848850564e-06 0.0001470555477004 4082.624248715471 2.4770740460601745e-06 0.0001752175636588 7073.569881268835 1.7857575055912413e-05 0.0004769818930159 2671.0339535042544 3.723783712817022e-06 0.0002633723401564 7072.707774351946 5.652831169901754e-05 0.001262888792145 2234.08192140825 1.628904035524443e-05 0.0006648992938749 4081.881310220375 +r_2194 fatty-acid--CoA ligase (dodecanoate), ER membrane 2.266714672457781e-10 1.786751146287958e-09 788.2558700476391 0.0002816606704008 0.0027672815760941 982.4877474571912 9.54024282511802e-10 4.260619711414948e-09 446.5944724380997 -0.0011953071160181 0.0171140985577153 -1431.7741715389582 6.401914386980476 79.74993479722323 1245.7201077135624 0.0004767899309343 0.003643530922127 764.1795024880663 0.0019097733747445 0.01524967135693 798.506857336918 4.600134582187297 67.6721870424031 1471.0914612029885 -0.004395764269575 0.0528442652253224 -1202.1633095996658 +r_2195 fatty-acid--CoA ligase (tetradecanoate), ER membrane 6.992109802391511e-05 0.0023797095291788 3403.421279747305 0.0002242836943551 0.0030257239559458 1349.0610472802591 -5.353794387524204e-05 0.0044607554810039 -8331.95143130391 -0.000635898675122 0.0157920908615885 -2483.428803898288 -4.200222253598137 64.67657871214558 -1539.837056401959 -3.0612597416246016e-10 4.9436800249065894e-09 -1614.9168780702653 0.0018888616403284 0.0167627458677162 887.4522892423956 -0.0008908027296397 0.013717912880015 -1539.949578462021 0.0051502745876991 0.0348108292705207 675.9023946735248 +r_2196 fatty-acid--CoA ligase (hexadecanoate), ER membrane 0.0001497843446888 0.0037328289105989 2492.1355555237164 0.0012937015183955 0.0096659979923132 747.1582783872047 0.0008756993269412 0.0078840345550748 900.3129627394926 0.0020918621931082 0.0126833734883406 606.319743725301 0.0026213331076243 0.0227580703517467 868.1868887839123 0.0024077890751407 0.0234871929102042 975.4672098440168 0.0025516952677307 0.0307613253544163 1205.5250383315674 0.0061250680880024 0.0493877131405335 806.3210470634926 0.0014737424047089 0.0437249333804556 2966.9318899112827 +r_2197 fatty-acid--CoA ligase (hexadecenoate), ER membrane 0.0011569838222657 0.007014411414487 606.2670263401166 0.0023054014353017 0.013500406084084 585.5989276903092 0.0008242630678248 0.0073825985425282 895.6604791247338 0.0023517832816982 0.0173789954449699 738.9709579200932 0.0065314548204215 0.0353567700528438 541.3306992845714 0.0035728121065745 0.0257971714893409 722.0410903184741 0.0026088497398767 0.0309242364059665 1185.3590466819064 0.0139182607942477 0.0782765362948323 562.4017070235029 -0.0019370692286831 0.003707457663229 -191.3952071681704 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0.0526554684086574 492.14378092937017 0.0257479023104346 0.0996999616428519 387.21586108569016 0.0173187422170356 0.0798894320641512 461.28888035279925 +r_2200 fatty-acid--CoA ligase (dodecanoate), lipid particle 0.0002246721050537 0.0020731137401684 922.728586921043 8.770231924298537e-05 0.0016998929893095 1938.2531773189733 0.0002882761127108 0.0028234539415983 979.4269511432792 0.001540367033419 0.0174681822256182 1134.0272705554676 -6.401020071135987 79.74994502331923 -1245.894312735158 0.0003549013110671 0.0059550085159816 1677.933648110535 -0.0006844175490628 0.010573156102449 -1544.840005480006 -4.597129897432425 67.67177382424399 -1472.043978179512 0.0066862496101837 0.0589672588585246 881.9182994411759 +r_2201 fatty-acid--CoA ligase (tetradecanoate), lipid particle 4.2645148803259597e-10 1.6908252853351908e-08 3964.871345942993 2.142046158856783e-09 1.0765450051786948e-08 502.577874303722 0.000184329022339 0.0023677675526728 1284.5332344452283 0.0009157358733007 0.0147691687586354 1612.8197211932654 4.20047038834985 64.6765621126343 1539.7456982917197 6.17147863607372e-10 1.2404726331823702e-08 2010.008794215896 -0.0017319909742736 0.0170867395836241 -986.5374495262608 -0.000276417812804 0.0073595587456065 -2662.4762966426515 -0.0053319139776179 0.0385241463777286 -722.5200282570819 +r_2202 fatty-acid--CoA ligase (hexadecanoate), lipid particle 0.0005851009475336 0.0043539917263919 744.1436806323396 0.0005110587923508 0.0071162268969956 1392.447797299615 0.0002505341273697 0.006222169086311 2483.561481876932 -0.0001041750381732 0.0092301978412006 -8860.277858356667 0.0009000816569468 0.0164012080010021 1822.191117263424 0.0014096943920092 0.0187188940701551 1327.868946366141 0.0025016510611292 0.0279294905045798 1116.4422943930783 0.0027063979119581 0.0388330286351013 1434.860279174714 0.0067430787593656 0.0562691500838184 834.4726806826155 +r_2203 fatty-acid--CoA ligase (hexadecenoate), lipid particle 0.0005542705394852 0.0047993353221592 865.8831708097011 0.0015355646530653 0.0105972011884816 690.1175516984712 0.0014957219771576 0.0097143580740654 649.476187581706 0.0019006654216674 0.012331924603764 648.8214318617429 0.0024474594348153 0.02090648158254 854.2115667023145 0.0024930394270351 0.0192347447951682 771.5379302301392 0.0092201669940533 0.0476826283354877 517.1557995233833 0.0061876627936032 0.0504838305367622 815.8788256682584 0.0170207830171883 0.0810535897492004 476.2036486062289 +r_2204 fatty-acid--CoA ligase (octadecanoate), lipid particle 6.709386037114205e-05 0.0052380441450167 7807.039445996326 0.0010077369537215 0.0077947445113373 773.4899948395864 0.0002208613358391 0.0062357598652922 2823.3823007543538 -0.0002063219197153 0.0119220613250883 -5778.378439641373 0.0023824662173977 0.02216228226899 930.2244081008264 0.0026098660433597 0.0153828686956637 589.4121935799078 0.0030621638985507 0.0312788867951057 1021.4635085309762 0.0044919796157504 0.0430959816851095 959.3984250062068 0.0027967344600835 0.0384633581135921 1375.295318971531 +r_2205 fatty-acid--CoA ligase (octadecenoate), lipid particle 0.0012118628131318 0.0071182456469953 587.3804831587553 0.001601811857089 0.012015705004885 750.1321051974866 0.0020611924485639 0.0105137556187842 510.0812214846366 0.0011488717888888 0.0199559939752411 1737.007921009361 0.0089003662319666 0.0384949113219453 432.50929589488766 0.0034890366760589 0.0264379404802445 757.743266548511 0.0076002042657576 0.042988415552503 565.6218444836471 -0.0002983316419868 0.0041218072841331 -1381.6192129947271 0.0106885416781523 0.0651706077546155 609.7240364214138 +r_2206 fatty-acid--CoA ligase (hexadecenoate), peroxisome 0.0001053361302459 0.0019560860590874 1856.994418269161 0.0001636984620156 0.003297179544776 2014.1786942759293 5.363743133327671e-05 0.0027586037727406 5143.057197500802 7.058800140667913e-05 0.0031864495675935 4514.151844639227 0.0002737466312617 0.006818156625268 2490.681472076134 0.0001357406754281 0.0043459588193689 3201.6628808288383 0.0005971113531126 0.0115880906278108 1940.6917264936649 0.0005899343347193 0.0151008019230924 2559.742844985732 0.0003688757468498 0.0106369405113902 2883.6107014976083 +r_2207 fatty-acid--CoA ligase (octadecanoate), peroxisome 0.0001650917269464 0.0021507545365838 1302.7633645633111 0.0004010330962833 0.0039643244296596 988.5279959185686 0.0002474641710291 0.0033277290945085 1344.7316759714763 0.0004481334435374 0.0050403155713877 1124.7354206821058 0.0007008102970264 0.0094990433397483 1355.4371817954818 0.000845793152717 0.0073896165660688 873.6907531504436 0.0007429492086713 0.0106290286782491 1430.6534759296517 0.0022084373098543 0.0235299927126346 1065.4589382112192 0.0013111808935326 0.019674351512194 1500.5062695190925 +r_2208 fatty-acid--CoA ligase (octadecenoate), peroxisome 0.000160067780252 0.0022853049817394 1427.710797351548 0.0002878074768981 0.004646493019855 1614.444860825878 0.0001511206518412 0.0024008600091749 1588.7041115312802 0.000243233398681 0.0040315746076868 1657.492198665373 0.0004112051510866 0.0068760139696274 1672.1614385074315 0.0006008190534664 0.0085371200530058 1420.9136683915506 0.0005586732228801 0.0149968318693913 2684.365610379055 0.000743896411928 0.0123887875149673 1665.3914868144873 0.0015187096868944 0.0216331374065233 1424.441918900261 +r_2209 fatty-acid--CoA ligase (arachidate), cell envelope 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2210 fatty-acid--CoA ligase (behenate), cell envelope 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2211 fatty-acid--CoA ligase (lignoceric acid), cell envelope 6.332172105245778e-10 1.7799941956553465e-08 2811.0325589235663 5.153357522444696e-10 1.1790701798690636e-08 2287.9650300484604 -4.2216718367520885e-10 5.159236458144924e-09 -1222.0837283539652 8.46819735529292e-10 4.236101302708419e-09 500.2364877645072 -2.9097619744904297e-10 9.771622072345211e-09 -3358.2204173440887 6.938857321375879e-11 9.953492738085407e-10 1434.4570405594916 -1.2705543565255966e-10 5.954516111540004e-09 -4686.549678852755 4.124626698114077e-09 1.8954244802053692e-08 459.5384307316886 1.0998109897537715e-09 9.156410223731968e-09 832.5439833786282 +r_2212 fatty-acid--CoA ligase (cerotic acid), cell envelope -6.332172105245643e-10 1.7799941956553422e-08 -2811.032558923618 -5.15335676218578e-10 1.1790701801998724e-08 -2287.965368226851 4.2216718367523176e-10 5.159236458144875e-09 1222.083728353887 -8.468197355290631e-10 4.2361013027091165e-09 -500.23648776472464 2.909761974483589e-10 9.771622072344196e-09 3358.220417351635 -6.938857321375879e-11 9.953492738085407e-10 -1434.4570405594916 1.2705543565255966e-10 5.954516111540004e-09 4686.549678852755 -4.124626698109708e-09 1.8954244802049298e-08 -459.5384307320688 -1.0998109897537715e-09 9.156410223731968e-09 -832.5439833786282 +r_2213 fatty-acid--CoA ligase (behenate), ER membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2214 fatty-acid--CoA ligase (lignoceric acid), ER membrane 0.0001328268061724 0.0024187135174727 1820.9528536983023 1.5529594370653987e-10 5.538132083402057e-09 3566.1794836492136 3.856780478541679e-11 2.634384381171037e-09 6830.527160745088 5.08675759592951e-10 6.227416096113302e-09 1224.240781808939 6.041897995872411e-10 8.859781209754254e-09 1466.3903984818855 -1.0206108820669816e-10 4.3723341798781476e-09 -4284.0364106476345 -1.1148933841955852e-10 3.1060508818719844e-09 -2785.9622506532805 -3.628002355335461e-09 2.0290044564043305e-08 -559.262166249812 6.359329399567619e-10 3.5228986100161566e-09 553.9732869091015 +r_2215 fatty-acid--CoA ligase (cerotic acid), ER membrane 1.3463874480129053e-05 0.0002342691508653 1739.9831765447725 1.57540326661109e-05 0.0003518708110676 2233.528509970304 -0.0004665115242708 0.0055046138903171 -1179.9523921560444 -0.0007721351335572 0.0162387574957046 -2103.097863309624 -2.199877694755046 46.85698092248759 -2129.9811818722524 3.521393295676021e-05 0.0007333546016291 2082.5694265098778 0.0008784159965578 0.015975470246079 1818.6679555791368 -4.601948429039055 67.67365829406138 -1470.5436042487877 0.0010693463643458 0.0208449088269963 1949.313105838104 +r_2216 fatty-acid--CoA ligase (behenate), lipid particle 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2217 fatty-acid--CoA ligase (lignoceric acid), lipid particle 2.300191837346424e-10 1.475565512582688e-08 6414.967171977047 1.2091125097972948e-10 8.20182800086524e-09 6783.345581496183 2.852066244019611e-10 5.241909078816278e-09 1837.93384526318 5.460923500843597e-10 8.146091547028306e-10 149.17058526401095 1.1818083970324995e-09 8.157722565142467e-09 690.2745475177167 -1.3165143483014342e-09 8.419046847566383e-09 -639.4952594651648 7.15836370185962e-11 3.2228159284115197e-09 4502.168460055037 3.1310849052031776e-10 4.615329352405041e-09 1474.0351961505014 6.390693908166992e-10 6.829557481780378e-09 1068.6722881614685 +r_2218 fatty-acid--CoA ligase (cerotic acid), lipid particle 3.2812242752254e-10 2.3027896029888707e-09 701.8080477996839 0.0001529452646787 0.0033253428456951 2174.2045121047736 0.0006487689791741 0.0071253183901941 1098.2828431877915 0.0012846069219233 0.0181120356358087 1409.928229928203 2.2003112032163368 46.85695995469331 2129.560576985631 4.5662555868608737e-10 1.0118748574521453e-08 2215.9838366554736 5.763343322938689e-10 2.35477515692031e-09 408.5779772216704 4.60282228485792 67.67360156638523 1470.2631858938737 3.503634200756923e-09 1.2566957011274932e-08 358.6834781028217 +r_2219 fatty acyl-CoA transport via ABC system (C12:0) 8.058240579075374e-05 0.0014750613680238 1830.500533645175 0.0001530132403953 0.0027581935873394 1802.58491370624 6.723521910700671e-05 0.0016802001226849 2498.98809731078 5.027405799060549e-05 0.0017769248700984 3534.4767085053754 0.0003029039825913 0.0060481971685791 1996.7374204979271 0.0003475082049985 0.0059504224990399 1712.3113680339138 0.0001132528857289 0.0046226036892467 4081.665256911055 0.0007124896970562 0.01399995869185 1964.934896559604 0.0005501624430386 0.0122909325488417 2234.055178495428 +r_2220 fatty acyl-CoA transport via ABC system (C14:0) 8.651617064565659e-05 0.0015302844346007 1768.7842898969104 0.0001483783551543 0.0022865391941437 1541.0193702207978 9.361452030193148e-05 0.0019938716014163 2129.8742919213573 0.0002216461110637 0.0036997609394378 1669.2198756300804 0.0002121045606301 0.0046761984904623 2204.6666401555103 3.31225692875016e-12 1.3476378777859522e-09 40686.39319880501 0.0003235601557208 0.007653690815663 2365.46146994272 9.75371559830424e-05 0.0034474190501009 3534.4674707352424 0.0002094788501973 0.0074318896005697 3547.799500316651 +r_2221 fatty acyl-CoA transport via ABC system (C16:0) 5.4826169088778034e-05 0.0011499019517361 2097.3596566161486 0.0001706259138861 0.0028237832282297 1654.955665241739 4.519510932838757e-05 0.0013022745049274 2881.450060149518 9.886123891864138e-05 0.002382363701705 2409.8056303599487 0.0001823563583428 0.0045545423280586 2497.6054410435554 9.294626864443457e-05 0.0023397696864313 2517.335790403982 0.000325631250612 0.0075854918988824 2329.472949731912 0.0003126774911027 0.0087657315947728 2803.441835182279 0.0006970836019263 0.0128435404389125 1842.4677331987043 +r_2222 fatty acyl-CoA transport via ABC system (C16:1) 4.354605342263768e-05 0.0010716741634467 2461.0132933187124 3.036619314058684e-05 0.0012341369094436 4064.180530400727 6.106856358441983e-05 0.0015929809574148 2608.512242493976 8.100505017444664e-05 0.0021003939938956 2592.9173420329234 0.0002336898140662 0.0053147164806519 2274.261076328401 0.000143027644122 0.0036893981060868 2579.500018148632 0.0004221292743053 0.0085073666848357 2015.3462938185205 0.0002824542323222 0.0087293385669773 3090.532046628798 0.0004503954015773 0.010997192279937 2441.67507959088 +r_2223 fatty acyl-CoA transport via ABC system (C18:0) 1.7841753217360632e-05 0.0006787294715045 3804.1635439959423 0.0001061994111088 0.0022655148638945 2133.264996708231 5.7380164213445314e-05 0.0015044705814571 2621.934952749036 5.2304913119475546e-05 0.0017185370970317 3285.6131375387627 7.39377429724929e-05 0.0020978631418239 2837.3372752322566 9.99395011739091e-05 0.0023303475774535 2331.7582638304507 0.0003666979386679 0.0080437236980522 2193.555744346732 0.0001849398822597 0.0070257569111415 3798.940945185273 0.0003883106421802 0.0098999910275504 2549.5028856190447 +r_2224 fatty acyl-CoA transport via ABC system (C18:1) 2.691505014127445e-05 0.0008521591573321 3166.106519806711 9.08305668803969e-05 0.0021267691946965 2341.4685911814454 5.5101985964044905e-05 0.0014839792152115 2693.15014558614 5.8452986834835184e-05 0.0018676412416252 3195.1168670003017 0.0001491454992557 0.0043044598705143 2886.080969250492 0.0003001038203368 0.0053618131774936 1786.6527561945418 0.0005697184297593 0.0101582735591688 1783.0340442837849 0.0003815035351657 0.0102235485484461 2679.804407056196 0.0002536594546645 0.0080615279453593 3178.090860449351 +r_2225 fatty acyl-CoA transport via ABC system (C20:0) 3.1111029417987564e-05 0.0006007813654654 1931.0880311728151 6.228595759657103e-05 0.0010234968349219 1643.22244437696 7.296707046735142e-05 0.0011410368858993 1563.7696273004829 7.998011400105734e-05 0.0014582619698275 1823.280684256409 0.0001620058207879 0.0029253695082319 1805.718766155769 9.599962668300368e-05 0.0020446712213766 2129.8741380820884 0.0003150926156547 0.0049796243032726 1580.36845545386 0.0003656873883287 0.0066671523141135 1823.1835515532337 0.000304517835485 0.005964913239978 1958.8058710835537 +r_2226 fatty acyl-CoA transport via ABC system (C22:0) 2.095228476552616e-05 0.0003954455776521 1887.3625577233508 4.35461783674002e-05 0.0007292837400357 1674.7364921045323 4.753738575082409e-05 0.0007338550344054 1543.7429358276736 5.507510004458529e-05 0.0009601285571608 1743.3078766694275 8.795607407471984e-05 0.0017229252786817 1958.8474096946657 0.0001053888597031 0.0017065511460217 1619.2898858838464 0.000158919682188 0.002782100115761 1750.6328212193607 0.0002631488117737 0.0045057404005031 1712.2404506148985 0.0002519333558057 0.0043138876130827 1712.3130040824972 +r_2227 fatty acyl-CoA transport via ABC system (C24:0) 1.5352082824230467e-05 0.0002897363615305 1887.2772173510991 3.5503099536859985e-05 0.000590651090594 1663.6606332942924 1.866481629424345e-05 0.0003951929788049 2117.315126893791 4.619179513988926e-05 0.0007497998391896 1623.2316516794576 5.526741432241645e-09 1.5627524181974752e-08 282.7619922800736 7.310781965700392e-05 0.0012163814480822 1663.8185269223516 7.66431744517689e-05 0.0016754239120086 2186.0053735939223 3.08523560230855e-09 1.3650387233687492e-08 442.4422959294742 4.510201708693468e-09 1.82359754680038e-08 404.327270615275 +r_2228 fatty acyl-CoA transport via ABC system (C26:0) 1.3812669458690668e-05 0.0002438143303445 1765.1499666569475 2.767369243194784e-05 0.0004623747455663 1670.809729143942 1.7541250426333123e-05 0.0003355518299853 1912.929932758109 2.316955401511373e-05 0.0004727535056088 2040.408310408104 8.784776950264994e-05 0.0013020270640894 1482.1401516064416 3.2327083047663246e-05 0.00071663738794 2216.832823683547 8.249779330855514e-05 0.0015569141019306 1887.2190873125348 0.0001942154103862 0.0029075155580871 1497.057083320273 0.0001976033366663 0.0029069834573947 1471.1206331007252 +r_2229 butyrate (n-C4:0) transport, cytoplasm-peroxisome -2.3419767843822785e-06 7.930420916535433e-05 -3386.208167997347 -3.4527139190816e-06 0.0001220347754567 -3534.45950972854 -4.971627777846386e-06 0.0001434456988261 -2885.2863737171388 -8.50892758373403e-06 0.000227273354561 -2670.998810655032 -9.775253910460403e-06 0.0003455027600852 -3534.4632809544587 -1.649973632202787e-05 0.0004122143487737 -2498.308704627446 -1.4540099263638914e-05 0.0005139990321345 -3535.044863276048 -3.8710198811700434e-05 0.0010341008783794 -2671.3912873703207 -2.6293348795235e-05 0.0008313793431633 -3161.937833167922 +r_2230 hexanoate (n-C6:0) transport, cytoplasm-peroxisome -2.9200998295507835e-06 9.180227080080418e-05 -3143.805902516925 -7.904056447913829e-06 0.0001765838283271 -2234.091184580532 -4.92325479733806e-06 0.0001420540929347 -2885.369512290328 -5.991034538416027e-06 0.0001893766476755 -3161.000766415093 -1.4425570286372067e-05 0.0004162780951153 -2885.6959333431123 -4.3052264502646e-06 0.0002152375014638 -4999.446694623342 -2.8909168283857305e-05 0.0007223478121956 -2498.6807129937206 -2.209297916206428e-05 0.0007808694823753 -3534.468921765882 -3.464640354133856e-05 0.0009397102580721 -2712.288035758022 +r_2231 octadecenoate (n-C18:1) transport, cytoplasm-peroxisome 1.531669321453653e-05 0.0009713814454777 6341.97885843837 -2.164907429658681e-05 0.0022723352173604 -10496.223470020388 1.0973427154105354e-05 0.0016493924769298 15030.787134835688 4.798347825490106e-05 0.0021713685036924 4525.241984663115 6.340543627339677e-05 0.0048560493260652 7658.727092621131 -0.0001132238440352 0.005687964907687 -5023.645819618196 -0.000157724379521 0.0108745989019642 -6894.684851500969 6.659818964209408e-05 0.011343337181694 17032.500797175442 0.0002099403148146 0.0094426783875242 4497.7918585385605 +r_2232 peroxisomal acyl-CoA thioesterase (4:0) 2.3419767843822777e-06 7.930420916535433e-05 3386.2081679973485 3.4527139190816e-06 0.0001220347754567 3534.45950972854 4.971627777846386e-06 0.0001434456988261 2885.2863737171388 8.50892758373403e-06 0.000227273354561 2670.998810655032 9.775253910460403e-06 0.0003455027600852 3534.463280954459 1.649973632202787e-05 0.0004122143487737 2498.308704627446 1.4540099263638914e-05 0.0005139990321345 3535.044863276048 3.8710198811700434e-05 0.0010341008783794 2671.3912873703207 2.6293348795235e-05 0.0008313793431633 3161.937833167922 +r_2233 peroxisomal acyl-CoA thioesterase (6:0) 2.9200998295507835e-06 9.18022708008042e-05 3143.805902516925 7.904056447913829e-06 0.0001765838283271 2234.091184580532 4.92325479733806e-06 0.0001420540929347 2885.369512290328 5.991034538416027e-06 0.0001893766476755 3161.000766415093 1.4425570286372067e-05 0.0004162780951153 2885.6959333431123 4.3052264502646e-06 0.0002152375014638 4999.4466946233415 2.8909168283857305e-05 0.0007223478121956 2498.6807129937206 2.209297916206428e-05 0.0007808694823753 3534.468921765882 3.464640354133856e-05 0.0009397102580721 2712.288035758022 +r_2234 peroxisomal acyl-CoA thioesterase (16:1) 0.0001280196403353 0.0021452360144821 1675.7085153980736 0.0001661180801205 0.0033537943319656 2018.921919595731 9.626315111881482e-05 0.0023916386047986 2484.47986275317 0.0001184656307685 0.0028220420218296 2382.1609723608285 0.0004188229153493 0.0078191391084494 1866.9320187333035 0.0002134633273317 0.0048328715608131 2264.0289651729345 0.0009241863083871 0.0137984123999676 1493.0336312867328 0.0006873620627281 0.0152803580758776 2223.043560948017 0.0006400238777772 0.0141114244337314 2204.8278077905643 +r_2235 peroxisomal acyl-CoA thioesterase (18:1) 0.0001447510870375 0.0023303788185901 1609.9214633091258 0.0003094565511947 0.0045251444066375 1462.2874808004103 0.0001401472246871 0.0025946198346989 1851.352990036631 0.0001952499204261 0.0039210892725242 2008.241162898501 0.0003477997148132 0.0069984548395057 2012.20833181624 0.0007140428975017 0.0096926200332256 1357.4282535598556 0.0007163976024012 0.0133508646284032 1863.6110148405555 0.0006772982222859 0.0141914872749239 2095.3085078279405 0.0013087693720797 0.0218902117857156 1672.5797724720414 +r_2236 acyl-CoA oxidase (butanoyl-CoA) 2.16800536625827e-05 0.0002378269351176 1096.9849928376882 9.730227159282893e-05 0.0006802256589172 699.0850755917538 7.123725236548811e-05 0.0005304334172975 744.6011738016954 0.0001247694820368 0.0008514871920508 682.4482863523134 0.0002830924381942 0.0018314697746197 646.9511465236999 7.566757643956248e-05 0.0008563018597261 1131.662860128926 0.0003546829115212 0.0025008338427849 705.0900287410617 0.0005680787037097 0.0039295216163388 691.7213390816277 0.0005170539563025 0.0036441668042889 704.7942985193228 +r_2237 acyl-CoA oxidase (hexanoyl-CoA) 3.506417587542736e-05 0.0003069108596112 875.283254058397 0.0001039288055358 0.0006991987517003 672.7670428764691 8.04213019799942e-05 0.0005635142569176 700.7027280630272 0.0001392828990704 0.0008994415060259 645.7659282142071 0.0003073539085225 0.0019064036076559 620.2633364320124 0.0001383325153475 0.0011737992379288 848.534587099476 0.0003874619504434 0.0026128533912417 674.3509622690483 0.0006455440334124 0.0041822307252134 647.8614174629129 0.0005787351811201 0.0038488323835201 665.0420622556188 +r_2238 acyl-CoA oxidase (octanoyl-CoA) 4.3840492748895696e-05 0.0003432844551343 783.0305583028394 0.0001174504522684 0.0007314838367579 622.802060469065 8.954190636764464e-05 0.0005926674141656 661.8883137603715 0.0001522939289238 0.0009365482087104 614.9609609053557 0.0003318733918712 0.0019740744859798 594.8275861614641 0.0001635517332038 0.0012730906586583 778.4024257765095 0.0004384420584249 0.0027682534701669 631.3841058295812 0.000700881571147 0.0043397716992294 619.1875885860367 0.0006355041212507 0.0040164735057509 632.0137622154133 +r_2239 acyl-CoA oxidase (icosanoyl-CoA) 8.122805298253694e-05 0.0008099033960005 997.0735063348396 0.0001690089279327 0.0014564668016705 861.7691500002429 0.0001567105614668 0.0014467068868349 923.1712740309248 0.0002044165634006 0.0019504822329152 954.170347288358 0.0003378152064478 0.0036261694238045 1073.418056556368 0.0003068233040376 0.0030031174296904 978.7774885971522 0.0006331533121167 0.006124055167037 967.2310086420308 0.0008230548287441 0.0085305020722233 1036.4439614842563 0.0007540591158599 0.0078909420252503 1046.461989422542 +r_2240 acyl-CoA oxidase (docosanoyl-CoA) 5.011700762551373e-05 0.0005460070204186 1089.464527688056 0.0001067229703361 0.0010426150922304 976.9359763378284 8.374348297207912e-05 0.000896224556587 1070.202151594135 0.0001244364491996 0.0013029813383417 1047.1058493893538 0.000175809378119 0.0021559891737584 1226.3220522279405 0.0002108236896495 0.0022087363579243 1047.6699092003269 0.0003180606577321 0.0035927523284966 1129.580864893397 0.0004573674281658 0.005352860653778 1170.3633280673537 0.0004495412194308 0.0051923595115665 1155.0352419606677 +r_2241 acyl-CoA oxidase (tetracosanoyl-CoA) 2.916474515330144e-05 0.0003781117076304 1296.4684095228836 6.317679196879714e-05 0.0007487951543506 1185.2376972868278 3.620608650994747e-05 0.0005178007455881 1430.1483410694182 6.936134915504181e-05 0.0008851862935919 1276.195322575526 8.785329624408013e-05 0.0013020268003653 1482.0466118288662 0.0001054348362963 0.0014101153283859 1337.4282902308662 0.0001591409683744 0.0022843769564059 1435.442412937192 0.0001942185987413 0.0029075155075882 1497.0324811476914 0.000197607846868 0.0029069833724318 1471.087013246092 +r_2242 acyl-CoA oxidase (palmitoleoyl-CoA) 2.0862543333162547e-05 0.0002495614330946 1196.2176859707768 2.794657503564686e-05 0.0003604127399062 1289.649051615594 1.844284379888178e-05 0.0002726030164763 1478.0964337665002 3.312742081260435e-05 0.0004427617053292 1336.5414344627616 8.861352997856212e-05 0.0010299139965031 1162.2536612099293 6.53049922184604e-05 0.0008414718325937 1288.5260437346292 9.50543190307892e-05 0.0012962030461169 1363.6445553800136 0.0001850265043133 0.0022365781486733 1208.787982550317 0.0001792472706499 0.0021320796653557 1189.4628340086151 +r_2243 acyl-CoA oxidase (cis-tetradec-7-enoyl-CoA) 2.0862543333162547e-05 0.0002495614330946 1196.2176859707768 2.794657503564686e-05 0.0003604127399062 1289.649051615594 1.844284537712485e-05 0.0002726030163695 1478.0963066993174 3.312742081260435e-05 0.0004427617053292 1336.5414344627616 8.861352997856212e-05 0.0010299139965031 1162.2536612099293 6.53049922184604e-05 0.0008414718325937 1288.5260437346292 9.50543190307892e-05 0.0012962030461169 1363.6445553800136 0.0001850265004609 0.002236578148992 1208.7880078910507 0.0001792472706499 0.0021320796653557 1189.4628340086151 +r_2244 acyl-CoA oxidase (cis-dodec-5-enoyl-CoA) 2.0862539520072865e-05 0.0002495614334132 1196.2179061334784 2.794657503564686e-05 0.0003604127399062 1289.649051615594 1.844284537712485e-05 0.0002726030163695 1478.0963066993174 3.312742081260435e-05 0.0004427617053292 1336.5414344627616 8.861352997856212e-05 0.0010299139965031 1162.2536612099293 6.53049922184604e-05 0.0008414718325937 1288.5260437346292 9.505431788155642e-05 0.0012962030462011 1363.6445719555202 0.0001850264965324 0.0022365781493171 1208.7880337317306 0.0001792472705999 0.00213207966536 1189.462834342765 +r_2245 acyl-CoA oxidase (oleoyl-CoA) 4.223174335581098e-05 0.0004638242795539 1098.283524897782 6.918149258380995e-05 0.0007940126462788 1147.7240756506108 6.607541311815006e-05 0.000714855934786 1081.8788730201582 0.0001064364650897 0.0011019594928503 1035.32139283404 0.0002125509355291 0.0022337022118851 1050.9020843988226 0.0001868799763016 0.0018686141617973 999.9006842666752 0.0004119940502382 0.003820581021289 927.3388824618384 0.0004481017248078 0.0048793835244867 1088.9008576299163 0.0004635997694792 0.0048929239501553 1055.419841052112 +r_2246 acyl-CoA oxidase (cis-hexadec-7-enoyl-CoA) 4.223172512638708e-05 0.0004638242812119 1098.2840029004485 6.918149258380995e-05 0.0007940126462788 1147.7240756506108 6.607543029211584e-05 0.0007148559331995 1081.8785894230132 0.0001064364650897 0.0011019594928503 1035.32139283404 0.0002125509728684 0.0022337022083324 1050.9018981132756 0.000186879963764 0.0018686141630514 999.9007520202512 0.0004119941073008 0.0038205810151349 927.3387525285248 0.0004481017507121 0.0048793835221076 1088.9007941505365 0.0004635997694792 0.0048929239501553 1055.419841052112 +r_2247 acyl-CoA oxidase (cis-tetradec-5-enoyl-CoA) 4.223172512638708e-05 0.0004638242812119 1098.2840029004485 6.918149258380995e-05 0.0007940126462788 1147.7240756506108 6.607543029140143e-05 0.0007148559331995 1081.8785894348175 0.0001064364650897 0.0011019594928503 1035.32139283404 0.0002125509629458 0.0022337022092766 1050.9019476170342 0.000186879963764 0.0018686141630514 999.9007520202512 0.0004119941072342 0.0038205810151421 927.3387526803256 0.0004481017507121 0.0048793835221076 1088.9007941505365 0.0004635997694791 0.0048929239501553 1055.419841052129 +r_2248 2-enoyl-CoA hydratase (3-hydroxydecanoyl-CoA) 7.324981212949177e-05 0.0004543895307149 620.3285953986001 0.0001257654615904 0.0007499685345547 596.3231280434618 0.000101396559069 0.0006318598172779 623.1570608305915 0.0001680019892753 0.0009835494748556 585.4391838442132 0.0003563107362173 0.0020442921917206 573.7385893624482 0.0002598844908445 0.0016370128575299 629.9001730384804 0.0004830437403873 0.0029073391154787 601.879058229307 0.0007391095702217 0.0044526170831537 602.4299051922708 0.0007283251562383 0.0043061248748595 591.2365978267305 +r_2249 2-enoyl-CoA hydratase (3-hydroxydodecanoyl-CoA) 6.836678222914591e-05 0.0004409538380122 644.9825831122599 0.0001194252007976 0.0007190288659199 602.0746551964049 9.469091772734846e-05 0.0006095527072082 643.7287987464236 0.0001528445142784 0.0009341997118306 611.2091861725415 0.0003087015584464 0.0018988785402391 615.1178989167296 0.0002681626928161 0.0016730504551704 623.8938152061072 0.0004613745539486 0.0028427908333229 616.1568315792963 0.0006697757169914 0.0042299666507877 631.5497178351599 0.0006490065439105 0.0040739857434687 627.7264507875656 +r_2250 2-enoyl-CoA hydratase (3-hydroxytetradecanoyl-CoA) 0.0002090015703217 0.0015207981593946 727.6491545272543 0.0003197672980343 0.0019236525924125 601.5788994801907 0.0003104013245283 0.0023440650718287 755.1723805915781 0.0004377289124604 0.0032684849624291 746.6915868218442 0.0008817518618033 0.0062527347672168 709.1263470007252 0.0007309436712479 0.0039635473219108 542.2507202427232 0.0015390036007872 0.0102683117637413 667.2051812281993 0.0029030280405835 0.0184364688049741 635.077186552704 0.0023280656738822 0.0165320779539908 710.1207727710853 +r_2251 2-enoyl-CoA hydratase (3-hydroxyhexadecanoyl-CoA) 0.0001559164264157 0.0012768663523271 818.9428026798172 0.0003322785952227 0.0026546755805372 798.930662012012 0.0002868750321416 0.0022804643321424 794.9330114641144 0.0004029261164038 0.0032301075260934 801.6624871383468 0.000716445893011 0.0059338468524374 828.2337731742747 0.0005799308198707 0.0035762477925967 616.6680007442345 0.0009804443320349 0.0083419646772849 850.835116764948 0.0012734640400243 0.0083562510647379 656.1827269640066 0.0015135328112166 0.0122616029038455 810.1312910414581 +r_2252 2-enoyl-CoA hydratase (3-hydroxyoctadecanoyl-CoA) 0.0001025024239969 0.0012895752229371 1258.0924164049393 0.0003573695226564 0.0026794028694519 749.7569601164959 0.0001665343971771 0.0019514240551907 1171.784381046173 0.0003293663836064 0.0031923104322111 969.2277630935588 0.0004237154405185 0.0055561900637527 1311.3022402375566 0.0007414198762234 0.0060338977601897 813.830051458104 0.0006563466998531 0.0086081859745324 1311.5303202496368 0.0014369306208613 0.0130282706767201 906.673606058336 0.0009537961458257 0.0125450413920101 1315.2749093098205 +r_2253 2-enoyl-CoA hydratase (3-hydroxyhexacosanoyl-CoA) 1.381266232907092e-05 0.0002438143307489 1765.150880694785 2.767369243194784e-05 0.0004623747455663 1670.809729143942 1.7541270215761327e-05 0.0003355518289557 1912.927768789616 2.3169554015113738e-05 0.0004727535056088 2040.408310408104 8.784776950264994e-05 0.0013020270640894 1482.1401516064416 3.232701663934004e-05 0.0007166373909397 2216.837386929269 8.24977939226892e-05 0.0015569141018982 1887.219073224246 0.0001942155135057 0.0029075155511991 1497.0562849052542 0.0001976033366663 0.0029069834573947 1471.1206331007252 +r_2254 2-enoyl-CoA hydratase (3-hydroxybutanoyl-CoA) 2.168005416254472e-05 0.000237826935072 1096.9849673299057 9.730227159282893e-05 0.0006802256589172 699.0850755917538 7.12372527162856e-05 0.0005304334172503 744.6011700688466 0.0001247694816368 0.0008514871921094 682.4482885871658 0.0002830924381942 0.0018314697746197 646.9511465236999 7.566759558905334e-05 0.0008563018580336 1131.662571497878 0.0003546829115212 0.0025008338427849 705.0900287410617 0.0005680787169723 0.0039295216144212 691.7213225949307 0.0005170539655528 0.0036441668029763 704.7942856564606 +r_2255 2-enoyl-CoA hydratase (3-hydroxyhexanoyl-CoA) 3.506417587542736e-05 0.0003069108596112 875.283254058397 0.0001039288055358 0.0006991987517003 672.7670428764691 8.04213019799942e-05 0.0005635142569176 700.7027280630272 0.0001392828990704 0.0008994415060259 645.7659282142071 0.0003073539085225 0.0019064036076559 620.2633364320124 0.0001383325153475 0.0011737992379288 848.534587099476 0.0003874619504434 0.0026128533912417 674.3509622690483 0.0006455440334124 0.0041822307252134 647.8614174629129 0.0005787351811201 0.0038488323835201 665.0420622556188 +r_2256 2-enoyl-CoA hydratase (3-hydroxyoctanoyl-CoA) 4.3840492748895696e-05 0.0003432844551343 783.0305583028394 0.0001174504522684 0.0007314838367579 622.802060469065 8.954190636764464e-05 0.0005926674141656 661.8883137603715 0.0001522939289238 0.0009365482087104 614.9609609053557 0.0003318733918712 0.0019740744859798 594.8275861614641 0.0001635517332038 0.0012730906586583 778.4024257765095 0.0004384420584249 0.0027682534701669 631.3841058295812 0.000700881571147 0.0043397716992294 619.1875885860367 0.0006355041212507 0.0040164735057509 632.0137622154133 +r_2257 2-enoyl-CoA hydratase (3-hydroxyicosanoyl-CoA) 8.122805298253694e-05 0.0008099033960005 997.0735063348396 0.0001690089279327 0.0014564668016705 861.7691500002429 0.0001567105614668 0.0014467068868349 923.1712740309248 0.0002044165634006 0.0019504822329152 954.170347288358 0.0003378152064478 0.0036261694238045 1073.418056556368 0.0003068233040376 0.0030031174296904 978.7774885971522 0.0006331533121167 0.006124055167037 967.2310086420308 0.0008230548287441 0.0085305020722233 1036.4439614842563 0.0007540591158599 0.0078909420252503 1046.461989422542 +r_2258 2-enoyl-CoA hydratase (3-hydroxydocosanoyl-CoA) 5.011700762551373e-05 0.0005460070204186 1089.464527688056 0.0001067229703361 0.0010426150922304 976.9359763378284 8.374348297207912e-05 0.000896224556587 1070.202151594135 0.0001244364491996 0.0013029813383417 1047.1058493893538 0.000175809378119 0.0021559891737584 1226.3220522279405 0.0002108236896495 0.0022087363579243 1047.6699092003269 0.0003180606577321 0.0035927523284966 1129.580864893397 0.0004573674281658 0.005352860653778 1170.3633280673537 0.0004495412194308 0.0051923595115665 1155.0352419606677 +r_2259 2-enoyl-CoA hydratase (3-hydroxytetracosanoyl-CoA) 2.916474515330144e-05 0.0003781117076304 1296.4684095228836 6.317679196879714e-05 0.0007487951543506 1185.2376972868278 3.620608650994747e-05 0.0005178007455881 1430.1483410694182 6.936134915504181e-05 0.0008851862935919 1276.195322575526 8.785329624408013e-05 0.0013020268003653 1482.0466118288662 0.0001054348362963 0.0014101153283859 1337.4282902308662 0.0001591409683744 0.0022843769564059 1435.442412937192 0.0001942185987413 0.0029075155075882 1497.0324811476914 0.000197607846868 0.0029069833724318 1471.087013246092 +r_2260 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-9-enoyl-CoA) 2.0862543333162547e-05 0.0002495614330946 1196.2176859707768 2.794657503564686e-05 0.0003604127399062 1289.649051615594 1.844284379888178e-05 0.0002726030164763 1478.0964337665002 3.312742081260435e-05 0.0004427617053292 1336.5414344627616 8.861352997861006e-05 0.0010299139965031 1162.2536612092952 6.53049922184604e-05 0.0008414718325937 1288.5260437346292 9.50543190307892e-05 0.0012962030461169 1363.6445553800136 0.0001850265043133 0.0022365781486733 1208.787982550317 0.0001792472706499 0.0021320796653557 1189.4628340086151 +r_2261 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-7-enoyl-CoA) 2.0862543333162547e-05 0.0002495614330946 1196.2176859707768 2.794657503564686e-05 0.0003604127399062 1289.649051615594 1.844284537712485e-05 0.0002726030163695 1478.0963066993174 3.312742081260435e-05 0.0004427617053292 1336.5414344627616 8.861352997856212e-05 0.0010299139965031 1162.2536612099293 6.53049922184604e-05 0.0008414718325937 1288.5260437346292 9.505431903078949e-05 0.0012962030461169 1363.6445553800097 0.0001850265004609 0.002236578148992 1208.7880078910507 0.0001792472706499 0.0021320796653557 1189.4628340086151 +r_2262 2-enoyl-CoA hydratase (3-hydroxy-cis-dodec-5-enoyl-CoA) 1.8887631768706167e-05 0.0002392775411368 1266.8477661306551 1.6099536493684987e-05 0.0002799541739506 1738.895862377697 1.3404244416782824e-05 0.0002363997380788 1763.6185280449538 2.803565932734585e-05 0.0004117875715464 1468.799312826595 7.398698714884598e-05 0.0009522586088084 1287.062286902819 5.209957014802479e-05 0.0007613302499466 1461.2985246971134 6.570030511243239e-05 0.0010939529283012 1665.0652176260355 0.0001357288086497 0.0019445504914632 1432.6733659626468 0.0001313364997137 0.0018418475179275 1402.388157094326 +r_2263 2-enoyl-CoA hydratase (3-hydroxy-cis-octadec-9-enoyl-CoA) 4.2231725126387046e-05 0.0004638242812119 1098.284002900449 6.918149258380995e-05 0.0007940126462788 1147.7240756506108 6.607543029211584e-05 0.0007148559331995 1081.8785894230132 0.0001064364650897 0.0011019594928503 1035.32139283404 0.0002125509728684 0.0022337022083324 1050.9018981132788 0.000186879963764 0.0018686141630514 999.9007520202512 0.0004119941073008 0.0038205810151349 927.3387525285492 0.0004481017507121 0.0048793835221076 1088.9007941505365 0.0004635997694792 0.0048929239501553 1055.419841052112 +r_2264 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-7-enoyl-CoA) 4.223172512638708e-05 0.0004638242812119 1098.2840029004485 6.918149258380995e-05 0.0007940126462788 1147.7240756506108 6.607543029211584e-05 0.0007148559331995 1081.8785894230132 0.0001064364650897 0.0011019594928503 1035.32139283404 0.0002125509728684 0.0022337022083324 1050.9018981132756 0.000186879963764 0.0018686141630514 999.9007520202512 0.0004119941073008 0.0038205810151349 927.3387525285248 0.0004481017507121 0.0048793835221076 1088.9007941505365 0.0004635997694792 0.0048929239501553 1055.419841052112 +r_2265 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-5-enoyl-CoA) 2.73774510059256e-06 8.654116160929917e-05 3161.037950193688 5.786066981619007e-06 0.0001557351237315 2691.554111389877 4.533246861743684e-06 0.0001275439354094 2813.522830310586 9.840598598319064e-06 0.0002314020177473 2351.503472430276 8.737715583032021e-06 0.000308151436472 3526.6819289753 1.8008061223903864e-05 0.0004246822609397 2358.2897440176034 1.6400514048912492e-05 0.0005178069091912 3157.2602398128847 2.676702398535304e-05 0.0007971208278425 2977.9957169642125 2.3896089139374114e-05 0.000754972295916 3159.396885041272 +r_2266 3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA) 7.324981212949177e-05 0.0004543895307149 620.3285953986001 0.0001257654615904 0.0007499685345547 596.3231280434618 0.000101396559069 0.0006318598172779 623.1570608305915 0.0001680019892753 0.0009835494748556 585.4391838442132 0.0003563107362173 0.0020442921917206 573.7385893624482 0.0002598844908445 0.0016370128575299 629.9001730384804 0.0004830437403873 0.0029073391154787 601.879058229307 0.0007391095702217 0.0044526170831537 602.4299051922709 0.0007283251562383 0.0043061248748595 591.2365978267305 +r_2267 3-hydroxyacyl-CoA dehydrogenase (3-oxododecanoyl-CoA) 6.836678222914591e-05 0.0004409538380122 644.9825831122599 0.0001194252007976 0.0007190288659199 602.0746551964049 9.469091772734846e-05 0.0006095527072082 643.7287987464236 0.0001528445142784 0.0009341997118306 611.2091861725415 0.0003087015584464 0.0018988785402391 615.1178989167296 0.0002681626928161 0.0016730504551704 623.8938152061072 0.0004613745539486 0.0028427908333229 616.1568315792963 0.0006697757169914 0.0042299666507877 631.5497178351599 0.0006490065439105 0.0040739857434687 627.7264507875656 +r_2268 3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA) 0.0001559164264157 0.0012768663523271 818.9428026798172 0.0003322785952227 0.0026546755805372 798.9306620120234 0.0002868750321416 0.0022804643321424 794.9330114641144 0.0004029261164038 0.0032301075260934 801.6624871383468 0.000716445893011 0.0059338468524374 828.2337731742747 0.0005799308198707 0.0035762477925967 616.6680007442345 0.0009804443320349 0.0083419646772849 850.835116764948 0.0012734640400243 0.0083562510647379 656.1827269640066 0.0015135328112166 0.0122616029038455 810.1312910414581 +r_2269 3-hydroxyacyl-CoA dehydrogenase (3-oxooctadecanoyl-CoA) 0.0001025024239969 0.0012895752229371 1258.0924164049393 0.0003573695226564 0.0026794028694519 749.7569601166206 0.0001665343971771 0.0019514240551907 1171.784381046173 0.0003293663836064 0.0031923104322111 969.2277630935588 0.0004237154405185 0.0055561900637527 1311.3022402375566 0.0007414198762234 0.0060338977601897 813.830051458104 0.0006563466998531 0.0086081859745324 1311.5303202496368 0.0014369306208613 0.0130282706767201 906.673606058336 0.0009537961458257 0.0125450413920101 1315.2749093098205 +r_2270 3-hydroxyacyl-CoA dehydrogenase (3-oxohexacosanoyl-CoA) 1.381266232907092e-05 0.0002438143307489 1765.150880694785 2.767369243194784e-05 0.0004623747455663 1670.809729143942 1.7541270215761327e-05 0.0003355518289557 1912.927768789616 2.316955401511373e-05 0.0004727535056088 2040.408310408104 8.784776950264994e-05 0.0013020270640894 1482.1401516064416 3.232701663934004e-05 0.0007166373909397 2216.837386929269 8.24977939226892e-05 0.0015569141018982 1887.219073224246 0.0001942155135057 0.0029075155511991 1497.0562849052542 0.0001976033366663 0.0029069834573947 1471.1206331007252 +r_2271 3-hydroxyacyl-CoA dehydrogenase (3-oxobutanoyl-CoA) 2.168005416254472e-05 0.000237826935072 1096.9849673299057 9.730227159282893e-05 0.0006802256589172 699.0850755917538 7.12372527162856e-05 0.0005304334172503 744.6011700688466 0.0001247694816368 0.0008514871921094 682.4482885871658 0.0002830924381942 0.0018314697746197 646.9511465236999 7.566759558905334e-05 0.0008563018580336 1131.662571497878 0.0003546829115212 0.0025008338427849 705.0900287410617 0.0005680787169723 0.0039295216144212 691.7213225949307 0.0005170539655528 0.0036441668029763 704.7942856564607 +r_2272 3-hydroxyacyl-CoA dehydrogenase (3-oxohexanoyl-CoA) 3.506417587542736e-05 0.0003069108596112 875.283254058397 0.0001039288055358 0.0006991987517003 672.7670428764691 8.04213019799942e-05 0.0005635142569176 700.7027280630272 0.0001392828990704 0.0008994415060259 645.7659282142071 0.0003073539085225 0.0019064036076559 620.2633364320124 0.0001383325031425 0.0011737992393673 848.5346630054785 0.0003874619504434 0.0026128533912417 674.3509622690483 0.0006455440293233 0.0041822307258447 647.8614216645093 0.0005787351805201 0.0038488323836103 665.0420629606866 +r_2273 3-hydroxyacyl-CoA dehydrogenase (3-oxooctanoyl-CoA) 4.3840492748895696e-05 0.0003432844551343 783.0305583028394 0.0001174504522684 0.0007314838367579 622.802060469065 8.954190636764464e-05 0.0005926674141656 661.8883137603715 0.0001522939289238 0.0009365482087104 614.9609609053557 0.0003318733918712 0.0019740744859798 594.8275861614641 0.0001635517332038 0.0012730906586583 778.4024257765095 0.0004384420584249 0.0027682534701669 631.3841058295812 0.000700881571147 0.0043397716992294 619.1875885860367 0.0006355041212507 0.0040164735057509 632.0137622154133 +r_2274 3-hydroxyacyl-CoA dehydrogenase (3-oxoicosanoyl-CoA) 8.122803279209483e-05 0.0008099033980266 997.0737566668024 0.0001690089279327 0.0014564668016705 861.7691500002429 0.0001567105675284 0.0014467068861783 923.1712379037996 0.0002044165633506 0.0019504822329205 954.170347524322 0.0003378152064739 0.0036261694238021 1073.4180564727667 0.0003068233090426 0.0030031174291791 978.7774724643316 0.0006331533121167 0.006124055167037 967.2310086420308 0.0008230548324011 0.0085305020718703 1036.443956836231 0.0007540591365818 0.0078909420232698 1046.461960402735 +r_2275 3-hydroxyacyl-CoA dehydrogenase (3-oxodocosanoyl-CoA) 5.011702356454968e-05 0.0005460070189598 1089.464178287801 0.0001067229703361 0.0010426150922304 976.9359763378284 8.374349099953702e-05 0.0008962245558369 1070.2020481112784 0.0001244364493996 0.0013029813383226 1047.1058476910428 0.0001758093856599 0.0021559891731435 1226.3219992780246 0.0002108236773546 0.0022087363590984 1047.6699708557887 0.0003180606964619 0.0035927523250676 1129.580726267924 0.0004573674404154 0.0053528606527311 1170.3632964928386 0.0004495412803749 0.0051923595062894 1155.0350841994086 +r_2276 3-hydroxyacyl-CoA dehydrogenase (3-oxotetracosanoyl-CoA) 2.9164722859988e-05 0.0003781117093541 1296.4694064446685 6.317679196879714e-05 0.0007487951543506 1185.2376972868278 3.620609722125591e-05 0.0005178007448394 1430.1479159024532 6.936134915504181e-05 0.0008851862935919 1276.195322575526 8.785330404430521e-05 0.0013020267998392 1482.046479643663 0.0001054348299463 0.0014101153288611 1337.4283712300578 0.0001591409755441 0.0022843769559066 1435.442347953263 0.000194218616392 0.0029075155064094 1497.0323444895275 0.0001976078636251 0.0029069833712926 1471.0868879219838 +r_2277 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-9-enoyl-CoA) 2.0862543333162547e-05 0.0002495614330946 1196.2176859707768 2.794657503564686e-05 0.0003604127399062 1289.649051615594 1.844284537712485e-05 0.0002726030163695 1478.0963066993174 3.312742081260435e-05 0.0004427617053292 1336.5414344627616 8.861352997856212e-05 0.0010299139965031 1162.2536612099293 6.53049922184604e-05 0.0008414718325937 1288.5260437346292 9.50543190307892e-05 0.0012962030461169 1363.6445553800136 0.0001850265004609 0.002236578148992 1208.7880078910507 0.0001792472706499 0.0021320796653557 1189.4628340086151 +r_2278 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-7-enoyl-CoA) 2.0862539520072865e-05 0.0002495614334132 1196.2179061334784 2.794657503564686e-05 0.0003604127399062 1289.649051615594 1.844284537712485e-05 0.0002726030163695 1478.0963066993174 3.312742081260435e-05 0.0004427617053292 1336.5414344627616 8.861352997856212e-05 0.0010299139965031 1162.2536612099293 6.53049922184604e-05 0.0008414718325937 1288.526043734629 9.505431788155642e-05 0.0012962030462011 1363.6445719555202 0.0001850264965324 0.0022365781493171 1208.7880337317306 0.0001792472705999 0.00213207966536 1189.462834342765 +r_2279 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-dodec-5-enoyl-CoA) 1.8887631768706167e-05 0.0002392775411368 1266.8477661306551 1.6099536493684987e-05 0.0002799541739506 1738.895862377697 1.3404244416782824e-05 0.0002363997380788 1763.6185280449538 2.803565932734585e-05 0.0004117875715464 1468.799312826595 7.398698714884598e-05 0.0009522586088084 1287.062286902819 5.209957014802479e-05 0.0007613302499466 1461.2985246971134 6.570030511243239e-05 0.0010939529283012 1665.0652176260355 0.0001357288086497 0.0019445504914632 1432.6733659626468 0.0001313364997137 0.0018418475179275 1402.388157094326 +r_2280 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-octadec-9-enoyl-CoA) 4.2231725126387046e-05 0.0004638242812119 1098.284002900449 6.918149258380995e-05 0.0007940126462788 1147.7240756506108 6.607543029211584e-05 0.0007148559331995 1081.8785894230132 0.0001064364650897 0.0011019594928503 1035.32139283404 0.0002125509728684 0.0022337022083324 1050.9018981132756 0.000186879963764 0.0018686141630514 999.9007520202512 0.0004119941073008 0.0038205810151349 927.3387525285248 0.0004481017507121 0.0048793835221076 1088.9007941505365 0.0004635997694792 0.0048929239501553 1055.419841052112 +r_2281 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-7-enoyl-CoA) 4.223172512638708e-05 0.0004638242812119 1098.2840029004485 6.918149258380995e-05 0.0007940126462788 1147.7240756506108 6.607543029211584e-05 0.0007148559331995 1081.8785894230132 0.0001064364650897 0.0011019594928503 1035.32139283404 0.0002125509629458 0.0022337022092766 1050.9019476170342 0.000186879963764 0.0018686141630514 999.9007520202512 0.0004119941072342 0.0038205810151421 927.3387526803256 0.0004481017507121 0.0048793835221076 1088.9007941505365 0.0004635997694792 0.0048929239501553 1055.419841052112 +r_2282 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-5-enoyl-CoA) 2.73774510059256e-06 8.654116160929917e-05 3161.037950193688 5.786066981619007e-06 0.0001557351237315 2691.554111389877 4.533246862690503e-06 0.0001275439354094 2813.522829722221 9.840598598319064e-06 0.0002314020177473 2351.503472430276 8.737715583032021e-06 0.000308151436472 3526.6819289753 1.8008061223903864e-05 0.0004246822609397 2358.2897440176034 1.6400514048912492e-05 0.0005178069091912 3157.2602398128847 2.676702398535304e-05 0.0007971208278425 2977.9957169642125 2.389608913938642e-05 0.000754972295916 3159.3968850396427 +r_2283 acetyl-CoA C-acyltransferase (acetyl-CoA) 2.1680149514691385e-05 0.0002378269263834 1096.9801025693018 9.730227169282892e-05 0.0006802256589029 699.0850748585827 7.123721800822962e-05 0.0005304334219117 744.6015393954797 0.0001247694816368 0.0008514871921094 682.4482885871658 0.0002830924465995 0.0018314697733203 646.9511268562167 7.566771904719228e-05 0.0008563018471248 1131.6607106800157 0.0003546829157349 0.0025008338421871 705.0900201960327 0.0005680787351013 0.0039295216117999 691.7213000587028 0.0005170539418646 0.003644166806338 704.7943185958319 +r_2284 acetyl-CoA C-acyltransferase (butanoyl-CoA) 3.506417587542736e-05 0.0003069108596112 875.283254058397 0.0001039288055358 0.0006991987517003 672.7670428764691 8.042130197999417e-05 0.0005635142569176 700.7027280630275 0.0001392828990704 0.0008994415060259 645.7659282142071 0.0003073539085225 0.0019064036076559 620.2633364320124 0.0001383325031425 0.0011737992393673 848.5346630054785 0.0003874619504434 0.0026128533912417 674.3509622690483 0.0006455440293233 0.0041822307258447 647.8614216645093 0.0005787351805201 0.0038488323836103 665.0420629606866 +r_2285 acetyl-CoA C-acyltransferase (hexanoyl-CoA) 4.3840492748895696e-05 0.0003432844551343 783.0305583028394 0.0001174504522684 0.0007314838367579 622.802060469065 8.954190636764464e-05 0.0005926674141656 661.8883137603715 0.0001522939289238 0.0009365482087104 614.9609609053557 0.0003318733918712 0.0019740744859798 594.8275861614641 0.0001635517332038 0.0012730906586583 778.4024257765095 0.0004384420584249 0.0027682534701669 631.3841058295812 0.000700881571147 0.0043397716992294 619.1875885860367 0.0006355041212507 0.0040164735057509 632.0137622154133 +r_2286 acetyl-CoA C-acyltransferase (stearoyl-CoA) 8.122803279209483e-05 0.0008099033980266 997.0737566668024 0.0001690089279327 0.0014564668016705 861.7691500002429 0.0001567105675284 0.0014467068861783 923.1712379037964 0.0002044165633506 0.0019504822329205 954.170347524322 0.0003378152064739 0.0036261694238021 1073.4180564727667 0.0003068233090426 0.0030031174291791 978.7774724643316 0.0006331533121167 0.006124055167037 967.2310086420308 0.0008230548324011 0.0085305020718703 1036.443956836231 0.0007540591365818 0.0078909420232698 1046.461960402735 +r_2287 acetyl-CoA C-acyltransferase (icosanoyl-CoA) 5.011702356454968e-05 0.0005460070189598 1089.464178287801 0.0001067229703361 0.0010426150922304 976.9359763378284 8.374349099953702e-05 0.0008962245558369 1070.2020481112784 0.0001244364493996 0.0013029813383226 1047.1058476910428 0.0001758093856599 0.0021559891731435 1226.3219992780246 0.0002108236773546 0.0022087363590984 1047.6699708557887 0.0003180606964619 0.0035927523250676 1129.580726267924 0.0004573674404154 0.0053528606527311 1170.3632964928386 0.0004495412803749 0.0051923595062894 1155.0350841994086 +r_2288 acetyl-CoA C-acyltransferase (docosanoyl-CoA) 2.9164722859988e-05 0.0003781117093541 1296.4694064446685 6.317679196879714e-05 0.0007487951543506 1185.2376972868278 3.620609722125591e-05 0.0005178007448394 1430.1479159024532 6.936134915504181e-05 0.0008851862935919 1276.195322575526 8.785330404430521e-05 0.0013020267998392 1482.046479643663 0.0001054348299463 0.0014101153288611 1337.4283712300578 0.0001591409755441 0.0022843769559066 1435.442347953263 0.000194218616392 0.0029075155064094 1497.0323444895275 0.0001976078636251 0.0029069833712926 1471.0868879219838 +r_2289 acetyl-CoA C-acyltransferase (cis-tetradec-7-enoyl-CoA) 2.0862543333162547e-05 0.0002495614330946 1196.2176859707768 2.794657503564686e-05 0.0003604127399062 1289.649051615594 1.844284537712485e-05 0.0002726030163695 1478.0963066993174 3.312742081260435e-05 0.0004427617053292 1336.5414344627616 8.861352997856212e-05 0.0010299139965031 1162.2536612099293 6.53049922184604e-05 0.0008414718325937 1288.5260437346292 9.50543190307892e-05 0.0012962030461169 1363.6445553800136 0.0001850265004609 0.002236578148992 1208.7880078910507 0.0001792472706499 0.0021320796653557 1189.4628340086151 +r_2290 acetyl-CoA C-acyltransferase (cis-dodec-5-enoyl-CoA) 2.0862539520072865e-05 0.0002495614334132 1196.2179061334784 2.794657503564686e-05 0.0003604127399062 1289.649051615594 1.844284537712485e-05 0.0002726030163695 1478.0963066993174 3.312742081260435e-05 0.0004427617053292 1336.5414344627616 8.861352997856212e-05 0.0010299139965031 1162.2536612099293 6.53049922184604e-05 0.0008414718325937 1288.5260437346292 9.505431788155643e-05 0.0012962030462011 1363.64457195552 0.0001850264965324 0.0022365781493171 1208.7880337317306 0.0001792472705999 0.00213207966536 1189.462834342765 +r_2291 acetyl-CoA C-acyltransferase (cis-dec-3-enoyl-CoA) 1.8887631768706167e-05 0.0002392775411368 1266.8477661306551 1.6099536493684987e-05 0.0002799541739506 1738.895862377697 1.3404244416782824e-05 0.0002363997380788 1763.6185280449538 2.803565932734585e-05 0.0004117875715464 1468.799312826595 7.398698714884598e-05 0.0009522586088084 1287.062286902819 5.209957014802479e-05 0.0007613302499466 1461.2985246971134 6.570030511243239e-05 0.0010939529283012 1665.0652176260355 0.0001357288086497 0.0019445504914632 1432.6733659626468 0.0001313364997137 0.0018418475179275 1402.3881570943252 +r_2292 acetyl-CoA C-acyltransferase (cis-hexadec-7-enoyl-CoA) 4.2231725126387046e-05 0.0004638242812119 1098.284002900449 6.918149258380995e-05 0.0007940126462788 1147.7240756506108 6.607543029211584e-05 0.0007148559331995 1081.8785894230132 0.0001064364650897 0.0011019594928503 1035.32139283404 0.0002125509728684 0.0022337022083324 1050.9018981132756 0.000186879963764 0.0018686141630514 999.9007520202512 0.0004119941073008 0.0038205810151349 927.3387525285248 0.0004481017507121 0.0048793835221076 1088.9007941505365 0.0004635997694792 0.0048929239501553 1055.419841052112 +r_2293 acetyl-CoA C-acyltransferase (cis-tetradec-5-enoyl-CoA) 4.223172512638708e-05 0.0004638242812119 1098.2840029004485 6.918149258380995e-05 0.0007940126462788 1147.7240756506108 6.607543029140143e-05 0.0007148559331995 1081.8785894348175 0.0001064364650897 0.0011019594928503 1035.32139283404 0.0002125509629458 0.0022337022092766 1050.9019476170342 0.000186879963764 0.0018686141630514 999.9007520202512 0.0004119941072342 0.0038205810151421 927.3387526803256 0.0004481017507121 0.0048793835221076 1088.9007941505365 0.0004635997694791 0.0048929239501553 1055.419841052129 +r_2294 acetyl-CoA C-acyltransferase (cis-dodec-3-enoyl-CoA) 2.73774510059256e-06 8.654116160929917e-05 3161.037950193688 5.786066981619007e-06 0.0001557351237315 2691.554111389877 4.533246862647272e-06 0.0001275439354094 2813.522829749095 9.840598598319064e-06 0.0002314020177473 2351.5034724302755 8.737715583032021e-06 0.000308151436472 3526.6819289753 1.8008061223903864e-05 0.0004246822609397 2358.2897440176034 1.6400514048912492e-05 0.0005178069091912 3157.2602398128847 2.676702398535304e-05 0.0007971208278425 2977.9957169642125 2.389608913938642e-05 0.000754972295916 3159.3968850396427 +r_2295 delta3,delta2-enoyl-CoA isomerase (cis-dec-3-enoyl-CoA) 1.8887547970002223e-05 0.0002392775477474 1266.8534217756323 1.6099536493684987e-05 0.0002799541739506 1738.895862377697 1.3404245162112503e-05 0.0002363997380365 1763.6184296651531 2.803565932734586e-05 0.0004117875715464 1468.7993128265944 7.398698714884598e-05 0.0009522586088084 1287.062286902819 5.209950229363615e-05 0.0007613302545898 1461.30043680449 6.570030497910448e-05 0.0010939529283093 1665.0652210172225 0.0001357287924155 0.0019445504925965 1432.6735381562198 0.0001313365073184 0.0018418475173852 1402.3880754795691 +r_2296 delta3,delta2-enoyl-CoA isomerase (trans-2,cis-5-dodecadienoyl-CoA) 1.974907751366648e-06 7.142678063920683e-05 3616.714785274354 1.1847038541961872e-05 0.0002278257736405 1923.0609644223528 5.0386009603419925e-06 0.000136244900565 2704.022438717243 5.091761485258832e-06 0.0001635679761143 3212.40452027992 1.4626542829715944e-05 0.0003950838209039 2701.142884573084 1.3205422070435776e-05 0.000360316305684 2728.5481960527363 2.9354012769126004e-05 0.0006980454521631 2378.023943960775 4.929768788269376e-05 0.0011110311282605 2253.718533218657 4.791077088620468e-05 0.0010797911442907 2253.7544779969585 +r_2297 delta3,delta2-enoyl-CoA isomerase (trans-dodec-3-enoyl-CoA) 1.9748821237439312e-06 7.142678134240376e-05 3616.761754215218 1.1847038541961872e-05 0.0002278257736405 1923.0609644223528 5.03860976163812e-06 0.0001362449002381 2704.017708922367 5.091761485258832e-06 0.0001635679761143 3212.40452027992 1.4626542829715944e-05 0.0003950838209039 2701.142884573084 1.320538779170454e-05 0.000360316306939 2728.555288360269 2.9354012827440333e-05 0.0006980454521606 2378.0239392282974 4.929768762602708e-05 0.0011110311282719 2253.718544975585 4.791076978110798e-05 0.0010797911443397 2253.754530083744 +r_2298 delta3,delta2-enoyl-CoA isomerase (cis-dodec-3-enoyl-CoA) 2.7377451005925764e-06 8.654116160929917e-05 3161.0379501936686 5.786066981619007e-06 0.0001557351237315 2691.554111389877 4.533246862690503e-06 0.0001275439354094 2813.522829722221 9.840598598319064e-06 0.0002314020177473 2351.503472430276 8.737715583032021e-06 0.000308151436472 3526.6819289753 1.8008022550777253e-05 0.0004246822625786 2358.2948176632704 1.6400513948912493e-05 0.0005178069091944 3157.260259083188 2.6767026477315786e-05 0.0007971208277588 2977.9954394052847 2.38960871048438e-05 0.0007549722959804 3159.3971543041184 +r_2299 delta3,delta2-enoyl-CoA isomerase (trans-2,cis-5-tetradecadienoyl-CoA) 3.949398002579452e-05 0.0004559163972528 1154.394662060109 6.339542560219079e-05 0.0007790611615286 1228.8917601363555 6.154218342943272e-05 0.0007037822382324 1143.5769727595723 9.659586649134082e-05 0.0010782713992285 1116.2707457313522 0.0002038132473628 0.0022131494615813 1085.8712523438965 0.00016887190254 0.0018213861083878 1078.5607794969944 0.0003955935931852 0.0037870429586549 957.3064437575764 0.0004213347267268 0.0048161751611583 1143.0757674718536 0.0004397036803398 0.004836500483228 1099.9454176708743 +r_2300 delta3,delta2-enoyl-CoA isomerase (trans-tetradec-3-enoyl-CoA) 3.94938624728037e-05 0.0004559164074327 1154.3981238773144 6.339542175388983e-05 0.0007790611618418 1228.8918352279486 6.154218206341364e-05 0.0007037822383519 1143.5769983370408 9.659586902259432e-05 0.0010782713990018 1116.2707162452343 0.0002038132339793 0.0022131494628141 1085.8713242530175 0.0001688716938384 0.0018213861277394 1078.562123905863 0.0003955935770745 0.003787042960338 957.30648316971 0.0004213346800748 0.0048161751652401 1143.0758950069817 0.0004397036703918 0.0048365004841322 1099.9454427620522 +r_2301 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-dodecadienoyl-CoA) 1.974907751366648e-06 7.142678063920683e-05 3616.714785274354 1.1847038541961872e-05 0.0002278257736405 1923.0609644223528 5.0386009603419925e-06 0.000136244900565 2704.022438717243 5.091761485258832e-06 0.0001635679761143 3212.40452027992 1.4626542829715944e-05 0.0003950838209039 2701.142884573084 1.3205422070435776e-05 0.000360316305684 2728.5481960527363 2.9354012769126004e-05 0.0006980454521631 2378.023943960775 4.929768788269376e-05 0.0011110311282605 2253.718533218657 4.791077088620468e-05 0.0010797911442907 2253.7544779969585 +r_2302 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-tetradecadienoyl-CoA) 3.949398002579452e-05 0.0004559163972528 1154.394662060109 6.339542560219079e-05 0.0007790611615286 1228.8917601363555 6.154218342943272e-05 0.0007037822382324 1143.5769727595723 9.659586649134082e-05 0.0010782713992285 1116.2707457313522 0.0002038132473628 0.0022131494615813 1085.8712523438965 0.00016887190254 0.0018213861083878 1078.5607794969944 0.0003955935931852 0.0037870429586549 957.3064437575764 0.0004213347267268 0.0048161751611583 1143.0757674718536 0.0004397036803398 0.004836500483228 1099.9454176708743 +r_2303 2,4-dienoyl-CoA reductase (trans-2,trans-4-dodecadienoyl-CoA) 1.9748821237439304e-06 7.142678134240376e-05 3616.7617542152193 1.1847038541961872e-05 0.0002278257736405 1923.0609644223528 5.03860976163812e-06 0.0001362449002381 2704.017708922367 5.091761485258832e-06 0.0001635679761143 3212.40452027992 1.4626542829715944e-05 0.0003950838209039 2701.142884573084 1.3205387791704543e-05 0.000360316306939 2728.555288360268 2.9354012827440333e-05 0.0006980454521606 2378.0239392282974 4.9297687626027095e-05 0.0011110311282719 2253.7185449755843 4.791076978110854e-05 0.0010797911443397 2253.7545300837164 +r_2304 2,4-dienoyl-CoA reductase (trans-2,trans-4-tetradecadienoyl-CoA) 3.9493960537663225e-05 0.0004559163989405 1154.3952359647658 6.339542560219079e-05 0.0007790611615286 1228.8917601363555 6.154218474255936e-05 0.0007037822381175 1143.5769481724187 9.659586649134082e-05 0.0010782713992285 1116.2707457313522 0.0002038132473628 0.0022131494615813 1085.8712523438965 0.0001688718870887 0.0018213861098206 1078.56087903072 0.0003955935936342 0.003787042958608 957.3064426591862 0.0004213347171469 0.0048161751619964 1143.0757936610153 0.0004397036803398 0.004836500483228 1099.9454176708743 +r_2305 cis-aconitate(3-) to isocitrate 6.490000000000322e-10 5.494173021250721e-10 84.655978755785 -0.0388416247109048 0.2972959939891495 -765.4056600410006 0.0242027165782208 0.0962431406091974 397.6542893362779 -0.0407602460159973 0.4893678432067578 -1200.6008084806308 0.6125502683380195 0.7124893044045103 116.31523831303625 0.1397911827509559 0.3847509491992426 275.2326302902045 0.2205003122071088 0.4116626700236293 186.69482410390785 0.1943366772362246 0.4375951850889868 225.1737506847825 1.5106220465370168 0.7494174602595122 49.60985853327728 +r_2308 glycerol-3-phosphate acyltransferase (16:0), ER membrane 0.000745834120371 0.0009776626573568 131.08312299663 0.0012029407659026 0.0016647645711626 138.39123407821873 0.0026556138690481 0.001415329807587 53.29576803627716 0.0039987991805743 0.0025263320425719 63.17726718672352 0.0055223139767835 0.0038611401914495 69.91888197017107 0.0065657346391368 0.0042914499665136 65.36130688153858 0.0073724044755379 0.0055552644968545 75.35213939071296 0.0090790061162836 0.0090708997831794 99.91071343051836 0.0100242707463298 0.0097263653174769 97.02815859236404 +r_2309 glycerol-3-phosphate acyltransferase (16:1), ER membrane 0.0007266270276574 0.0008988241772949 123.69814816724464 0.0011812632824436 0.001456077598109 123.26444237705444 0.0026124154479591 0.0013364674047246 51.15830277947112 0.0038690511327105 0.0019299940812193 49.88287864438895 0.0056447104783994 0.0045228286144589 80.12507695065035 0.0064732259945469 0.0029995589870641 46.33793088007389 0.0074910112819072 0.0062234563536536 83.07898786222488 0.0089935247627374 0.0105686546234397 117.51404373987393 0.0097909466161497 0.0082299714822652 84.05695388728046 +r_2310 glycerol-3-phosphate acyltransferase (18:0), ER membrane 0.0002349278151594 0.0008958499394966 381.32987313085385 0.0003218993187494 0.0008970954126865 278.6881985869388 0.0007721994165417 0.0015987742996622 207.04163528409288 0.0010999631294018 0.0019879312450443 180.7270800181633 0.0015570370549292 0.003457495151346 222.05606092677627 0.0017049692648696 0.0021118583563447 123.86489304287826 0.0022882973834682 0.006361971788963 278.02207155962003 0.0028082651472727 0.0091271159958469 325.0090542451385 0.0030904751992552 0.009495313730198 307.24445653167373 +r_2311 glycerol-3-phosphate acyltransferase (18:1), ER membrane 4.8969456688737566e-05 0.0007017239975755 1432.983016405331 9.25559824572109e-05 0.0013810270795962 1492.099206266521 0.000118643221908 0.0011993958063751 1010.926530050623 0.0002308312748915 0.0023198923775296 1005.0164903433196 0.0003134879716486 0.0037436943356131 1194.206691862778 0.0004555251756493 0.0042605453185017 935.3040284607736 0.000585591033077 0.0064362529577595 1099.103742067222 0.0008759130727334 0.0101580045585971 1159.7046413403584 0.0006941380250775 0.0086237332752582 1242.3657779437049 +r_2312 dihydroxyacetone phosphate acyltransferase (16:0), ER membrane 1.1696045362375434e-05 0.0004035875792772 3450.632814536738 2.8396265978947523e-05 0.0008478381296364 2985.738090582102 1.1413700122665804e-05 0.0004002666897954 3506.896847592414 6.097689273868363e-05 0.0013863579224698 2273.5791546660857 8.851353917598513e-05 0.0024273463801558 2742.344733645503 4.354651357398683e-05 0.0013380564426848 3072.706246417345 0.0001040042240104 0.0028460886442537 2736.5125516136422 0.0001098086385577 0.0034854926955608 3174.15163446079 0.0001515001799202 0.0041331466188853 2728.1463434972766 +r_2313 dihydroxyacetone phosphate acyltransferase (16:1), ER membrane 1.5855330147929323e-05 0.0004751226372528 2996.61144120002 5.261310225406455e-05 0.0012022973195533 2285.167131463867 4.083474211537391e-05 0.0008693502693236 2128.947617368116 3.121326938790665e-05 0.0008553726780475 2740.4135959526984 0.0001842549125118 0.0036581285350526 1985.362824352061 5.809767929261126e-05 0.0015901778168534 2737.0763104743137 0.0001261431648911 0.003352547931907 2657.7325333472068 0.00033174695608 0.0071080499092844 2142.611945343209 5.1673043421017065e-05 0.0007046990717788 1363.7653699572854 +r_2314 dihydroxyacetone phosphate acyltransferase (18:0), ER membrane 1.3535796000521045e-05 0.0004521234885647 3340.2061359920103 1.7352089220940436e-05 0.0005775740374319 3328.556176018837 2.6334250139934928e-05 0.0007723860817379 2933.009588781252 5.3797450054588825e-05 0.001349744137119 2508.937014206829 7.769119830223828e-05 0.002304622604623 2966.388284625834 2.4560193779179703e-05 0.0010697892959581 4355.785241666376 3.039538930168256e-05 0.0015553319436697 5116.999582511258 0.0001059471783106 0.0040614543232654 3833.470969237691 0.0001360174512318 0.0043510682007282 3198.904376844627 +r_2315 dihydroxyacetone phosphate acyltransferase (18:1), ER membrane 1.3213104154325273e-05 0.0004607806193552 3487.3002889663903 1.2069341807520277e-05 0.0005884111072425 4875.25431482904 1.9221216855461405e-05 0.0006778004496161 3526.3139410632944 2.423206549974296e-05 0.0009365428341504 3864.8906514403593 3.1982715656447745e-05 0.0015071753247877 4712.468262474994 1.427689761025708e-05 0.0008953351140278 6271.216187644136 0.0001758724249021 0.0043384310237817 2466.805712262719 7.245161655251679e-05 0.0033873268607949 4675.295075493045 0.000298715140807 0.00689718233423 2308.9496955514205 +r_2316 glycerol-3-phosphate acyltransferase (16:0), lipid particle 7.093626154626875e-05 0.0008973324583938 1264.9841404576084 9.047485650532786e-05 0.0011873618360747 1312.366641891105 0.0001197773493738 0.001027225688512 857.6126403545686 0.0001992648839841 0.0017198552418168 863.1000141268213 0.0003928084815137 0.0036248762867781 922.810086179762 0.0004136412073703 0.0026779601635263 647.4113593640429 0.0004965734297553 0.0049687554859198 1000.6084071730644 0.0003948401657556 0.0068933033894981 1745.846544336531 0.0008286740538594 0.0072345247471765 873.0241659531489 +r_2317 glycerol-3-phosphate acyltransferase (16:1), lipid particle 3.390188635576996e-05 0.0006676131813443 1969.250838547233 6.76825593395203e-05 0.0013684284161078 2021.8331420408376 8.8175903883976e-05 0.001175607849524 1333.2529611161526 8.854293388671573e-05 0.0016072228162907 1815.1903779776665 0.000171903005495 0.0031928234162595 1857.3400779495155 0.0002091929796071 0.0034384388408348 1643.6683713246036 0.0002177076870311 0.0045274963986173 2079.621744348514 0.0002132728683314 0.0058959837095268 2764.52591258012 0.0004715720071734 0.0078860696471553 1672.2938442474024 +r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 3.566430345802618e-05 0.0007158914969653 2007.305421814436 0.0001123703803783 0.0016051188303934 1428.4180804492985 5.571230225436814e-05 0.0010389829384515 1864.9075633382256 0.0001055391176203 0.0018035576323637 1708.8996696480876 0.0001415206626311 0.0027473491725091 1941.306040708152 0.0001864107593711 0.0025344666650769 1359.6139373215815 0.0002997580420982 0.0054577125514484 1820.705964465952 0.0002263518103698 0.0056629613063703 2501.8405185791435 0.0004035064819029 0.0076102019939803 1886.0172848005143 +r_2319 glycerol-3-phosphate acyltransferase (18:1), lipid particle 4.110345641994008e-05 0.0008351240644027 2031.7611635152543 5.021265547682667e-05 0.0012424032864291 2474.2831754885174 5.033154337888925e-05 0.0011194052618411 2224.0630560727886 8.604845632555933e-05 0.0017738435242355 2061.4472356416213 0.0002364597990455 0.0038860331352042 1643.4223283997185 0.0001167237299141 0.0026697688466304 2287.2545699106854 0.0002562542414053 0.0053991582903863 2106.953727195322 0.0001446322023537 0.0050648878221845 3501.9088002234384 0.0002666205084629 0.0065442898683829 2454.533563869224 +r_2320 dihydroxyacetone phosphate acyltransferase (16:0), lipid particle 2.4018381834690256e-05 0.0005811000772013 2419.397281635396 6.029318804451555e-05 0.0013058294402164 2165.799292703345 2.2599983413590244e-05 0.0006143200726288 2718.2324048052656 2.9205937376127293e-05 0.0008706145505444 2980.9505489662524 9.294864319134784e-05 0.0024384201195562 2623.405824801964 7.200199971375903e-05 0.0018069990625703 2509.651217680072 0.0001668531348916 0.0040969401809403 2455.416965105818 0.0003360841707404 0.0072259420841834 2150.0393988400247 0.0003078792049246 0.006894528895442 2239.361666900786 +r_2321 dihydroxyacetone phosphate acyltransferase (16:1), lipid particle 3.346190675470841e-05 0.000718241466787 2146.445126549595 1.953790789046249e-05 0.0007356265467781 3765.124448852778 2.635356001656659e-05 0.0007035737082646 2669.748253451884 5.5928136339819545e-05 0.0013341133770037 2385.4064596353314 7.259519061341925e-05 0.0020985975804659 2890.8217785959737 0.0001185126318652 0.0024853305003561 2097.1017698627406 9.9853720821303e-05 0.003169995126315 3174.638962115416 0.0003286200649581 0.0071881084689733 2187.3614046932107 9.387290381208138e-05 0.0035157421456624 3745.215075801251 +r_2322 dihydroxyacetone phosphate acyltransferase (18:0), lipid particle 1.2812665700933816e-05 0.00039709152085 3099.210813102733 2.214944168059677e-05 0.0007556825459242 3411.7453470002424 2.209164865311671e-05 0.0006699677976988 3032.6745107108227 1.854313439957662e-05 0.0007453709850508 4019.660155555546 4.592597238261089e-05 0.0016037714351012 3492.0794310899773 9.973920045613588e-05 0.0023274532114827 2333.539070735142 0.0001699055312365 0.0041688162648904 2453.6083284336128 0.000187741434993 0.0053462157373792 2847.6482762458286 0.0002623021619175 0.0063842168576999 2433.916979954645 +r_2323 dihydroxyacetone phosphate acyltransferase (18:1), lipid particle 1.4891174314492376e-05 0.0004317180999259 2899.1541621118527 3.20305354849545e-05 0.0009190330063639 2869.2402185898013 5.901892037547336e-05 0.0011743408165301 1989.7700755267103 3.117757065416089e-05 0.0010525064400842 3375.844935961382 6.363079748647417e-05 0.0020575852125356 3233.631030591845 9.224139128864184e-05 0.0021607735243592 2342.5205259510267 0.0001537582830007 0.0040515915502229 2635.039538131449 6.870335146813572e-05 0.0033232119677018 4837.0449136577845 0.0001919176965657 0.0054718042890591 2851.120239026649 +r_2324 acyl dhap reductase (16:0), ER membrane 1.1696045362375434e-05 0.0004035875792772 3450.632814536738 2.8396265978947523e-05 0.0008478381296364 2985.738090582102 1.1413700122665804e-05 0.0004002666897954 3506.896847592414 6.097689273868363e-05 0.0013863579224698 2273.5791546660857 8.851353917598513e-05 0.0024273463801558 2742.344733645503 4.354651357398683e-05 0.0013380564426848 3072.706246417345 0.0001040042240104 0.0028460886442537 2736.5125516136427 0.0001098086385577 0.0034854926955608 3174.151634460791 0.0001515001799202 0.0041331466188853 2728.1463434972766 +r_2325 acyl dhap reductase (16:1), ER membrane 1.5855330147929323e-05 0.0004751226372528 2996.61144120002 5.2613102254064536e-05 0.0012022973195533 2285.1671314638675 4.08347421153739e-05 0.0008693502693236 2128.947617368116 3.121326938790664e-05 0.0008553726780475 2740.413595952699 0.0001842549125118 0.0036581285350526 1985.362824352061 5.809767929261126e-05 0.0015901778168534 2737.0763104743137 0.0001261431648911 0.003352547931907 2657.7325333472068 0.00033174695608 0.0071080499092844 2142.611945343209 5.1673043421017065e-05 0.0007046990717788 1363.7653699572854 +r_2326 acyl dhap reductase (18:0), ER membrane 1.3535796000521045e-05 0.0004521234885647 3340.2061359920103 1.7352089220940436e-05 0.0005775740374319 3328.556176018837 2.6334250139934928e-05 0.0007723860817379 2933.009588781252 5.3797450054588825e-05 0.001349744137119 2508.937014206829 7.769119830223828e-05 0.002304622604623 2966.388284625834 2.4560193779179703e-05 0.0010697892959581 4355.785241666376 3.039538930168256e-05 0.0015553319436697 5116.999582511258 0.0001059471783106 0.0040614543232654 3833.470969237691 0.0001360174512318 0.0043510682007282 3198.904376844627 +r_2327 acyl dhap reductase (18:1), ER membrane 1.3213104154325273e-05 0.0004607806193552 3487.3002889663903 1.2069341807520277e-05 0.0005884111072425 4875.25431482904 1.9221216855461405e-05 0.0006778004496161 3526.3139410632944 2.423206549974296e-05 0.0009365428341504 3864.8906514403593 3.198271565644774e-05 0.0015071753247877 4712.468262474995 1.427689761025708e-05 0.0008953351140278 6271.216187644136 0.0001758724249021 0.0043384310237817 2466.8057122627188 7.24516165525168e-05 0.0033873268607949 4675.295075493044 0.000298715140807 0.00689718233423 2308.949695551421 +r_2328 acyl dhap reductase (16:0), lipid particle 2.4018381834690256e-05 0.0005811000772013 2419.397281635396 6.029318804451555e-05 0.0013058294402164 2165.799292703345 2.2599983413590244e-05 0.0006143200726288 2718.232404805265 2.9205937376127293e-05 0.0008706145505444 2980.9505489662524 9.294864319134784e-05 0.0024384201195562 2623.405824801964 7.200199971375903e-05 0.0018069990625703 2509.651217680072 0.0001668531348916 0.0040969401809403 2455.416965105818 0.0003360841707404 0.0072259420841834 2150.0393988400247 0.0003078792049246 0.006894528895442 2239.361666900786 +r_2329 acyl dhap reductase (16:1), lipid particle 3.3461906754708404e-05 0.000718241466787 2146.445126549595 1.95379078904625e-05 0.0007356265467781 3765.124448852778 2.635356001656659e-05 0.0007035737082646 2669.748253451884 5.5928136339819545e-05 0.0013341133770037 2385.4064596353314 7.259519061341927e-05 0.0020985975804659 2890.821778595973 0.0001185126318652 0.0024853305003561 2097.1017698627406 9.9853720821303e-05 0.003169995126315 3174.638962115416 0.0003286200649581 0.0071881084689733 2187.361404693211 9.387290381208138e-05 0.0035157421456624 3745.215075801251 +r_2330 acyl dhap reductase (18:0), lipid particle 1.281266570093382e-05 0.00039709152085 3099.210813102733 2.214944168059677e-05 0.0007556825459242 3411.7453470002424 2.209164865311671e-05 0.0006699677976988 3032.6745107108227 1.854313439957662e-05 0.0007453709850508 4019.660155555546 4.592597238261089e-05 0.0016037714351012 3492.0794310899773 9.973920045613588e-05 0.0023274532114827 2333.539070735142 0.0001699055312365 0.0041688162648904 2453.6083284336128 0.000187741434993 0.0053462157373792 2847.6482762458286 0.0002623021619175 0.0063842168576999 2433.916979954645 +r_2331 acyl dhap reductase (18:1), lipid particle 1.4891174314492376e-05 0.0004317180999259 2899.1541621118527 3.20305354849545e-05 0.0009190330063639 2869.2402185898013 5.901892037547336e-05 0.0011743408165301 1989.7700755267103 3.117757065416089e-05 0.0010525064400842 3375.844935961382 6.363079748647415e-05 0.0020575852125356 3233.631030591845 9.224139128864184e-05 0.0021607735243592 2342.5205259510267 0.0001537582830007 0.0040515915502229 2635.039538131449 6.870335146813573e-05 0.0033232119677018 4837.044913657784 0.0001919176965657 0.0054718042890591 2851.120239026649 +r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 0.0003623800901663 0.0007627066166729 210.4714462439008 0.0006166497734256 0.0014807331730135 240.12547102508373 0.0012760314451013 0.0010278316699554 80.54908630200629 0.0019871410933117 0.0022654540880735 114.0056987245902 0.0028273707254665 0.0042278344352732 149.53236932081876 0.0031746712461136 0.0033625040247905 105.91660566135226 0.0035998404155619 0.0042288652580948 117.47368688383342 0.0044594421251161 0.0076175437259747 170.8183111755575 0.0047240770760258 0.0064746224012152 137.05581634290473 +r_2333 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 0.0003951500755671 0.0007396793258266 187.18946839754344 0.0006146872584559 0.0011406435084221 185.56485313967656 0.0013909961240694 0.0012061067648104 86.70813267846268 0.0020726349800012 0.0018630168533701 89.88639443733517 0.002783456790493 0.0018546453733157 66.63101003221419 0.0034346099065971 0.0032913625364144 95.82929723962212 0.0038765682839864 0.0046676764387972 120.40743505225346 0.0047293726297254 0.0062037603985796 131.1751237275577 0.0054516938502242 0.0085269431090216 156.40906006985105 +r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 0.0006962832529034 0.0008958262482311 128.6583074482462 0.0011525583119641 0.0015474374275179 134.26109650634072 0.0025085364444191 0.0011847511012116 47.228777714090775 0.0037290155300539 0.0018526317429025 49.68152392960791 0.0055395533834883 0.0052899814961371 95.49472908601108 0.0061978703243258 0.0022444142737363 36.21266913131935 0.0071340390980138 0.0054068390083576 75.78931001181324 0.0084958731340237 0.0090829547288093 106.91019728666276 0.009327718098243 0.0061070250857507 65.47180158565324 +r_2335 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 4.619910490189639e-05 0.0004493993609623 972.7447358919098 8.131807273358117e-05 0.0010079406862941 1239.5039041277194 0.0001447137456553 0.0009351171552553 646.1840587572194 0.0001712488720445 0.0009360186974315 546.5838614037376 0.0002894120074229 0.001963787903079 678.5440315919589 0.0003334533495137 0.0026016346585556 780.2094842800557 0.0004831153487846 0.0044199248079477 914.879814741356 0.0008293985847937 0.0086826174827902 1046.8570409906108 0.0005149015613277 0.0055935778012367 1086.339258092832 +r_2336 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-16:1), ER membrane 0.0001800977765766 0.000691599453982 384.0133216124528 0.0002720804307187 0.0008026804545149 295.015871738597 0.0005866056594179 0.000783897065844 133.63271445793515 0.0009243263044676 0.0017958382217205 194.2861750272139 0.0013970019991014 0.0039634877824908 283.7138232472302 0.0014437255404257 0.0020517918432273 142.11786006240436 0.0017376660033071 0.0042906400466466 246.9197209636784 0.0022162029845242 0.0074465789393895 336.00617774585 0.0023332086753502 0.0060293726807171 258.4154921253289 +r_2337 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), ER membrane 6.836583458334881e-05 0.0007128691597891 1042.7272103583198 6.717097725168087e-05 0.0006978460124439 1038.9100188750274 0.0002119280072637 0.0015090327190752 712.0496901559748 0.0002294342749887 0.0014931490579398 650.795988529959 0.00023772625413 0.0009118395653018 383.56704379950975 0.0002858039182231 0.0011499647077235 402.3614213804227 0.0005810267694628 0.0047630605163389 819.7661048806193 0.000698009341059 0.0065979485432216 945.2521843347464 0.0008932839751369 0.0084447421383776 945.3591885025568 +r_2338 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-16:1), ER membrane 3.325908006706684e-05 0.0005990446460551 1801.1461677447105 4.181373627014112e-05 0.0008757903054696 2094.5038247993275 6.588249743923378e-05 0.0008182324381005 1241.9572267357971 0.0001214781614847 0.0016298925065203 1341.716475289651 0.0002469828279572 0.0034250293943894 1386.747986780235 0.0002858316379102 0.0034124956322752 1193.8831044822246 0.0002935627176402 0.0042586040323856 1450.662422877762 0.0004218554791643 0.0068306962801529 1619.202930274382 0.0004042343833534 0.0063175323957279 1562.838950838159 +r_2339 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), ER membrane 2.892348077599597e-05 0.0005571864723124 1926.4156919000395 6.281158799459223e-05 0.0012171532653124 1937.7845779304887 7.198194132426315e-05 0.0009860231402377 1369.820155024563 0.0001335851789064 0.001781542871968 1333.6381225457935 9.848785934789609e-05 0.0020666489180527 2098.3793654734177 0.0001839704353494 0.0026288964709084 1428.9776865047068 0.0004679007403389 0.0061053835930316 1304.845892872243 0.0005265092101216 0.0081574315502306 1549.3426123251743 0.0005886187825311 0.0086073448961648 1462.295317718436 +r_2340 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), lipid particle 9.495464338095811e-05 0.0010674617489632 1124.1806729562838 0.0001507680445498 0.0017618474346535 1168.5814722303933 0.0001423773327874 0.0011946610855444 839.0809563259252 0.0002284708213602 0.0019246375616779 842.3997209880617 0.000485757124705 0.0043603426422824 897.638432978201 0.0004856432070841 0.0032213564816388 663.3175208977661 0.000663426564647 0.0064271071967324 968.7744716933458 0.000730924336496 0.0099732852375988 1364.4757384066536 0.0011365532587841 0.0099680746268904 877.0442167887722 +r_2341 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), lipid particle 6.736379311047755e-05 0.0009794431396292 1453.9607917014246 8.722046722998271e-05 0.0015527708993591 1780.282711929112 0.0001145294639005 0.0013683644758077 1194.7706984781175 0.0001444710702265 0.0020864126136819 1444.1732939406777 0.0002444981961084 0.0038174951804791 1561.359241597608 0.0003277056114723 0.0042367599998622 1292.8554933271962 0.0003175614078524 0.0055230069853337 1739.193380796576 0.0005418929332896 0.0092893125502532 1714.2339343420374 0.0005654449109855 0.0086291357571932 1526.0789494335424 +r_2342 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 4.847696915896e-05 0.0008180881476631 1687.5810552028256 0.0001345198220589 0.0017727051890792 1317.8022108169205 7.780395090748444e-05 0.0012352652946597 1587.6639685414216 0.0001240822520199 0.0019505084384265 1571.9479673154844 0.0001874466350137 0.0031791521882749 1696.0305465292436 0.0002861499598272 0.0034356029023556 1200.63022354767 0.0004696635733348 0.0068603042011077 1460.6847519378248 0.0004140932453629 0.0077824463299956 1879.39465739776 0.0006658086438205 0.0099227856811249 1490.3359656291298 +r_2343 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 5.599463073443212e-05 0.0009394617152164 1677.7710700015352 8.224319096178093e-05 0.0015443348966355 1877.7662668186308 0.0001093504637543 0.00162055616319 1481.9838046872485 0.0001172260269797 0.0020612918280937 1758.390931776887 0.000300090596532 0.004393724174082 1464.1325735818864 0.0002089651212027 0.0034314822003037 1642.1315579140994 0.0004100125244061 0.006744441129277 1644.9353928993762 0.0002133355538219 0.0060561496863967 2838.7906178318863 0.0004585382050287 0.0085244362394056 1859.0460175225207 +r_2344 PA phosphatase (1-16:0, 2-16:1), ER membrane 0.0001515679668545 0.0025893915944283 1708.4029351089694 0.000329015993228 0.0054086433644996 1643.8846365596078 0.0002199598054996 0.0032596604875593 1481.9346108054726 0.0003668895685792 0.004865891325789 1326.2550212674792 0.0008983387307319 0.0128769297846902 1433.41585352757 0.0009922114464491 0.0135427024625335 1364.9008496121703 0.0008111196985856 0.0117504087566825 1448.6651941964883 0.0020319620862846 0.0301692689723568 1484.7358214010978 0.0017504318099798 0.0265683891982137 1517.8191487801598 +r_2345 PA phosphatase (1-16:0, 2-18:1), ER membrane 0.0001671913331531 0.0021413066108146 1280.752160073696 0.0002836566016387 0.0041684828580015 1469.5525624711831 0.000390133543563 0.0052903136415494 1356.0263476023567 0.0005256878826871 0.0073724022996929 1402.4295675236258 0.00065180419135 0.0093846455041541 1439.795206704118 0.0006957507842106 0.0087124392384323 1252.2356332400286 0.0008548814941551 0.0116997264288003 1368.5787455677898 0.0014593367346672 0.0207070166228778 1418.9334189274082 0.002007520778711 0.024622812473281 1226.528399326946 +r_2346 PA phosphatase (1-16:1, 2-16:1), ER membrane 0.0003749448206365 0.0032380257696422 863.6006130569731 0.0006533347173386 0.0056861413551127 870.3259147585842 0.0008460190643521 0.0035087978325285 414.7421707589425 0.001236503082636 0.0048530400194652 392.4810287669547 0.0019965532661606 0.0102702638854585 514.3996936885151 0.0019885270397525 0.0079791897696959 401.26131604872495 0.0028576296630018 0.0185104928246711 647.7568827174956 0.0035746718173008 0.0257323041357742 719.8508129119449 0.0033226732106237 0.0210484709304842 633.480020339802 +r_2347 PA phosphatase (1-16:1, 2-18:1), ER membrane 0.0001371096130513 0.0020502439289593 1495.332007239974 0.0002783925802494 0.0041381898894597 1486.4583983353416 0.0002620982216613 0.0040711600492705 1553.2955635731128 0.000349528455202 0.0058995998556767 1687.8739821817603 0.0009285622593976 0.0145704980184961 1569.1460503626818 0.0008674981454531 0.0112422312464005 1295.937208087932 0.001356130103071 0.0200956364299918 1481.8369111108632 0.0024357966428589 0.0330524452283954 1356.946004720687 0.0015568644565072 0.0246266298350995 1581.8094974271653 +r_2348 PA phosphatase (1-18:0, 2-16:1), ER membrane 0.0001576883049379 0.0028134657951951 1784.1943296321977 0.0002940491898475 0.0052098677402789 1771.7674185666556 0.0001564202926202 0.0034853751254839 2228.211613148201 0.0003457767092634 0.00627187273975 1813.8505491332944 0.0005956774636345 0.0085942941078208 1442.7764406903632 0.0004622455895183 0.0088103975761912 1905.9992731074303 0.0004477728999903 0.0112614271444851 2514.986312197233 0.0013072125849517 0.0232765532363662 1780.624934637238 0.0013484300545746 0.0246237583244167 1826.1057175994783 +r_2349 PA phosphatase (1-18:0, 2-18:1), ER membrane 0.0002061707283602 0.0030625435006471 1485.440501182832 0.0004475283023523 0.0064729327983478 1446.373953183219 0.0003338654350166 0.0041490102530194 1242.7193167847936 0.0004717453299622 0.0067663232667192 1434.3169581054603 0.000388601534276 0.0080369881122438 2068.182290431996 0.0005904602959045 0.0086046774756041 1457.2829935029122 0.0018560404333837 0.0232565889285092 1253.0216750779373 0.0014343043528203 0.0232462188736656 1620.73125051569 0.0025520704194295 0.0321142503249488 1258.3606659305017 +r_2350 PA phosphatase (1-18:1, 2-16:1), ER membrane 0.0002409190917581 0.0037053093153956 1537.989076895457 0.0001708909510309 0.0038127945724208 2231.127247768152 0.0001909234442873 0.0039251503425346 2055.87656203509 0.000378055631181 0.006751323063851 1785.8014818507136 0.0008010247309007 0.013205385679067 1648.561544937255 0.0004468356083753 0.0067009297742697 1499.640952661318 0.0009087174132364 0.0166980803958059 1837.5437900253933 0.001468772420305 0.0242012808792635 1647.7216309819444 0.0015322811069041 0.0267560647449117 1746.1590190177894 +r_2351 PA phosphatase (1-18:1, 2-18:1), ER membrane 0.0001833167653478 0.0026616138206135 1451.9205679650238 0.0003653771292431 0.0049265002882848 1348.3329672246634 0.0003211976919277 0.0043213221574493 1345.3777116249948 0.0003852768142572 0.0054107535045095 1404.3807735850685 0.0010386477704924 0.0134377973540826 1293.7780964677588 0.0008588514387092 0.0112895120396508 1314.4895066622664 0.0010734511988589 0.0128965516584006 1201.4101500012218 0.0018874632783359 0.0288027489471156 1526.0031428271936 0.0017210232764871 0.0221961733346521 1289.70791028214 +r_2352 PA phosphatase (1-16:0, 2-16:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2353 PA phosphatase (1-16:0, 2-18:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2354 PA phosphatase (1-16:1, 2-16:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2355 PA phosphatase (1-16:1, 2-18:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2356 PA phosphatase (1-18:0, 2-16:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2357 PA phosphatase (1-18:0, 2-18:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2358 PA phosphatase (1-18:1, 2-16:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2359 PA phosphatase (1-18:1, 2-18:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 7.41928977008638e-05 0.0023334394272341 3145.0981152431227 0.0002418829277528 0.0056741262765219 2345.8151136317574 0.0001787543084742 0.0044331554624224 2480.0271950153706 0.0001806183323827 0.005352902354606 2963.65395693251 0.0003386862034758 0.0106228368971235 3136.4835024587514 0.0002280665723567 0.0077984241569642 3419.3630729741244 0.0010362867667198 0.0225905675509944 2179.9532983036925 0.0010539064893428 0.0280836442860889 2664.7187933723826 0.0004425123731984 0.0180155977705881 4071.207690842813 +r_2361 PA phosphatase (1-16:0, 2-18:1), Golgi membrane 9.429069101488323e-05 0.0025882991170511 2745.020838422514 0.000134715313306 0.0042490815596027 3154.1191979774185 0.0001600210884092 0.0042556506929815 2659.431163284083 0.0001458079489639 0.0048013835391512 3292.9504689329124 0.0002805991629539 0.0095163376169043 3391.4347843102355 0.0002746963410276 0.0086720954405606 3156.9752287625465 0.0005276567440113 0.0160163742231574 3035.377526192034 0.0008237389163052 0.0245145524312798 2976.0099888488685 0.0016159897479212 0.0343936407112625 2128.332853318276 +r_2362 PA phosphatase (1-16:1, 2-16:1), Golgi membrane 7.744767068146313e-05 0.0023396799843544 3020.981733559729 0.0002842774790295 0.0060371531924334 2123.683245343155 0.0001505904633692 0.0039574630659762 2627.963934391658 0.000357739791701 0.0075100184090979 2099.296355428477 0.0004266954058222 0.0116484300091378 2729.91690329823 0.0005796180867464 0.0122853893481107 2119.566250437781 0.0004310814735451 0.0142914127689314 3315.2463387954967 0.00095406085691 0.0264970721219735 2777.29370511972 0.0007806150537026 0.0232391019155348 2977.0245661168133 +r_2363 PA phosphatase (1-16:1, 2-18:1), Golgi membrane 7.494925781477871e-05 0.0023335534199787 3113.511044693252 0.0002151101761335 0.0053739835317257 2498.247004544427 0.0002215137191642 0.0048654843357346 2196.470879588243 0.000201589528498 0.0058044972738886 2879.3644774776026 0.0008074401233511 0.0162242843012698 2009.3482887540208 0.0004519973192524 0.0109950888472223 2432.556207502838 0.00080782997212 0.020150822156869 2494.43853933589 0.0013524009528531 0.0310517096874707 2296.0431684080168 0.000589357904808 0.0207853024075439 3526.770785285794 +r_2364 PA phosphatase (1-18:0, 2-16:1), Golgi membrane 0.0001359799956568 0.0031355005348447 2305.854269003322 0.000244072256759 0.005702904297712 2336.5639230932184 6.878261124106272e-05 0.0027893232508547 4055.273855595513 0.0002429197327616 0.006295533583983 2591.6106165658584 0.0006714481767862 0.0149886758972372 2232.2908029890764 5.528934368163945e-05 0.0038819208044353 7021.101257392003 0.0003018833702723 0.0122981903697436 4073.821740710491 0.0009190621795276 0.0264636528068129 2879.419194511198 0.0007624313517475 0.0233047560242428 3056.636636311822 +r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.0001251671853875 0.0029730542646444 2375.266532868017 0.0001043001378471 0.0034114175929169 3270.769975316224 0.0001813603030309 0.0045260554850483 2495.615307984374 0.0001798942314637 0.005369123553671 2984.600178662576 0.0004684878267641 0.0125058010920634 2669.39723459626 0.000438682047909 0.0109460687072611 2495.216925204601 0.0005042115557964 0.0159184709868755 3157.1015784697115 0.0012232623605508 0.0305217078327856 2495.107249032141 0.001615561122114 0.0343713439001708 2127.517395020928 +r_2366 PA phosphatase (1-18:1, 2-16:1), Golgi membrane 0.0001034988825511 0.0027636369537622 2670.209460856712 0.0001982204913362 0.0050728759306795 2559.2086350323075 0.00015973591359 0.0042577023275019 2665.463408829273 0.000269114027801 0.0067231353820764 2498.2478382905765 0.0007352949013251 0.0156551521720593 2129.098426202321 0.0001646453473126 0.00671988401289 4081.4296441245774 0.0009913428089221 0.0221709104348888 2236.4524395950434 0.0012250975203021 0.0305791914550623 2496.06181943134 0.0015904814710301 0.0339139015392883 2132.3040951443554 +r_2367 PA phosphatase (1-18:1, 2-18:1), Golgi membrane 8.858663282303293e-05 0.0025559833654995 2885.292378823756 0.0002475258689424 0.0057058583264988 2305.15636643475 0.0003071355676349 0.005794472980335 1886.617373870252 0.0003479944322925 0.0075156890031062 2159.715301648522 0.0002014164128152 0.0082009553513109 4071.642045790914 0.0002604790278438 0.008274425017709 3176.6185117478167 0.0011245056638338 0.0236135952775108 2099.908967732822 0.0008215056743211 0.0244872285898744 2980.774126741066 0.0008967306781125 0.0254340572300352 2836.309479627492 +r_2368 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:0), ER membrane 3.987071093600737e-05 0.0011879698077653 2979.5551167173408 0.0001009242947486 0.0027594924488927 2734.220195212225 8.270628083020251e-05 0.002168993223729 2622.5254018881446 8.959503023465591e-05 0.0026050112387571 2907.539884672674 0.0003289005267387 0.0075587438592935 2298.1853918700954 0.0004543924872186 0.0080647629305562 1774.8451300155332 0.0003358900441515 0.0094021478791444 2799.1743259004443 0.0010379343775049 0.0212440883256087 2046.766037047217 0.0004496978051364 0.012895427846397 2867.5763366210385 +r_2369 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:0), ER membrane 3.337563544518268e-05 0.001156309838514 3464.5328039167007 8.197366972237753e-05 0.0025171148967546 3070.6382979796026 8.041596425169598e-05 0.0022012834503286 2737.3712058451883 0.0001516380170465 0.0036299412020865 2393.8200147871603 0.0002010129273694 0.0061195289989144 3044.3459925673374 0.000205376375638 0.0055485153862207 2701.632731117531 0.0002552401847631 0.008456607028119 3313.1957790912984 0.0004391344502671 0.0135811260496323 3092.70339445478 0.0005419574435019 0.0152748751749217 2818.463951010972 +r_2370 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:0), ER membrane 4.289462944678748e-05 0.0013177465715959 3072.0549136126256 9.700519308639108e-05 0.002718168054454 2802.085092530374 7.456341962426406e-05 0.0021591356556108 2895.703639252353 8.652328081729249e-05 0.0028059181964351 3242.9632463432654 0.0002361411965436 0.0064223904451859 2719.7246982694123 0.0002086014680117 0.0056472504729176 2707.195940059348 0.0003127156362618 0.0094846799660098 3033.0047065723898 0.000481382973071 0.0145049851270922 3013.190315925745 0.0005087256956256 0.0142780586562627 2806.6320964389383 +r_2371 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:0), ER membrane 4.123835794428235e-05 0.0013125056323633 3182.7301032127907 8.069502449126966e-05 0.0025357860077335 3142.4316724854134 9.731571327461006e-05 0.0025365655756423 2606.5323782651126 0.0001298865997193 0.0034607423472018 2664.433709619462 0.0002274408597309 0.0065340203706395 2872.8436826912143 0.0001627256051501 0.0048544307503725 2983.20030574928 0.0004869734819451 0.0120144237770821 2467.161811171567 0.0002772468669142 0.0112629316568062 4062.4198145731634 0.0008465116345712 0.0189204181568062 2235.1043251036094 +r_2372 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-16:0), ER membrane 2.22890037127479e-05 0.0009302733929105 4173.687639427662 8.094099834804705e-05 0.002532777676735 3129.1653530688004 6.429692444510245e-05 0.0019520282224049 3035.958934663473 0.0001655187107752 0.0040442363720864 2443.3711168630784 0.0002269871093451 0.0064220194995737 2829.2441443488137 0.00030740130108 0.006877808308355 2237.403772914915 0.0002442147611372 0.0083331957636888 3412.2408182384142 0.0002754429123638 0.0110995683188916 4029.716438748464 0.0001905898924402 0.0088289398592774 4632.4281661710365 +r_2373 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-16:0), ER membrane 6.305267581239918e-05 0.0015876213574512 2517.928600167413 0.0002085137923438 0.0040768227425131 1955.1813319808389 7.536831635592086e-05 0.0021692967690071 2878.260884537733 9.819123528408988e-05 0.0029850180172415 3040.004546846934 0.0001329796817341 0.0047239358278676 3552.374141872307 0.0003143085075053 0.0068208524679212 2170.1138547147125 0.0003108907663739 0.0095547088398466 3073.333103869932 0.000453834713246 0.014310619952172 3153.2669349630182 0.0003645748203375 0.011724214600189 3215.8596661540896 +r_2374 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:0), ER membrane 4.720909086276955e-05 0.0013340878963444 2825.913128093141 0.0001430857798247 0.0033511459960005 2342.053836589578 6.59292670709559e-05 0.0020622659422165 3127.997676657033 0.0001344689621791 0.0035468410747463 2637.665240564251 0.0002924830667107 0.0073747743063467 2521.4363310956933 0.0001969788694035 0.0053088133820831 2695.1182114900043 0.0002682655483509 0.0083954454919554 3129.52801564037 0.0009813778766213 0.0208741416485575 2127.0238657123377 0.0003898333778857 0.0126344169323902 3240.978748641548 +r_2375 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:0), ER membrane 6.630990882103558e-05 0.001671843708088 2521.25773932247 9.626810337309644e-05 0.0027609329808857 2867.962371903712 6.488786859958212e-05 0.0020035863751364 3087.767279736699 0.0001993020756297 0.0043591337054443 2187.1993513720004 0.0002470156130993 0.0065580271814151 2654.903914424639 0.0001927307864215 0.0055383902734963 2873.6406758509165 0.0001041452400254 0.005112746071601 4909.246039809242 0.0004365104154415 0.0138001313068922 3161.4666726638966 0.0002716532516435 0.0107912775294471 3972.445558504425 +r_2376 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:1), ER membrane 0.000109264735145 0.0021341636751656 1953.204455519764 0.0001176969720894 0.0030020043556013 2550.6215685144875 3.732419355995607e-05 0.0010041303869916 2690.2935903455323 0.0002526488719467 0.00461682833244 1827.3694621572804 0.000487468651594 0.0095416306671505 1957.3834411603848 0.0003997647436956 0.007390426776326 1848.6939863690995 0.0005358867051065 0.0121266870817723 2262.919935541608 0.0007591908958885 0.0177077003785457 2332.4437206033663 0.0003902584182942 0.0121573374685101 3115.2018505190795 +r_2377 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membrane 7.630846802450106e-05 0.0017700399746952 2319.585257729102 0.0001016662688012 0.002771099266534 2725.682076471889 5.40813261255292e-05 0.001687659010957 3120.594726245731 0.000108663205681 0.0029428598385509 2708.239481899124 0.0002231777393792 0.0063822887052299 2859.73355720001 0.0002571596969193 0.0058384710460726 2270.3678360231743 0.0005333136266953 0.0120264394209063 2255.040715053284 0.0009212702957732 0.0198620854075205 2155.945491637648 0.0006996988630485 0.0165458602495675 2364.7116100028747 +r_2378 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 0.000205422057861 0.0015389269617391 749.153707134962 0.0004284686166519 0.0037689425945928 879.6309573483331 0.00062325339039 0.0019736762282502 316.6731635451094 0.0010518269956688 0.0042616820920909 405.1694917167561 0.0018950486472012 0.0116008374745534 612.1656819568321 0.0018035384040659 0.008123291343304 450.408559362561 0.0017034229396918 0.0062092855896007 364.5181384444701 0.0023757698187095 0.0159194104666098 670.0737731930928 0.0021766047193792 0.0065432826178683 300.61878298850456 +r_2379 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 5.676118915534256e-05 0.0015301284885042 2695.730148141627 0.0001673258229061 0.0035667123058675 2131.5970505446016 6.234431915659912e-05 0.0016413284055798 2632.683182339454 0.0004081898158017 0.0060536507838672 1483.0479716837388 0.0003357472888178 0.0077342276639105 2303.586036730569 0.0002760372643925 0.0060084187292201 2176.669422674423 0.0005535241817482 0.0120674696984036 2180.116080979652 0.0005458491873854 0.0146936772873819 2691.8932237975496 0.0005768606362147 0.0151728644488869 2630.2478443406026 +r_2380 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-16:1), ER membrane 0.0001106363595939 0.0021624643720873 1954.569347747728 0.000215922570144 0.0040874295223889 1893.0070717766205 6.439011840380165e-05 0.001698593877701 2637.972906104779 0.0004085885468163 0.0059420441833631 1454.285547077072 0.0007422027114273 0.0115339676757667 1554.0185313504808 0.0002443521795092 0.0057042719510237 2334.446929215236 0.0002170312377979 0.0064301700202395 2962.7854890760555 0.0008630424180857 0.0192549402830247 2231.0537558204314 0.0003181203218004 0.0107806694451693 3388.865377777598 +r_2381 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-16:1), ER membrane 9.752117249926466e-05 0.0020191574092554 2070.4810632487724 0.0001672965908807 0.0034771456841884 2078.431883089998 6.312140828046537e-05 0.0016860787383714 2671.1678086771994 0.0003235289502422 0.0053750366242908 1661.377326593433 0.0004321465095092 0.0087241221114384 2018.788054390668 0.0004520668252959 0.0077599929869406 1716.5588255364455 0.000359689848244 0.0096032643356119 2669.8736098596346 0.001472081152712 0.0253961910702997 1725.189608162065 0.0003295111471737 0.0108023869067743 3278.306970621798 +r_2382 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:1), ER membrane 8.565308866653936e-05 0.0018641480164811 2176.393222360693 0.0001592896260411 0.0033303649270043 2090.760716673866 6.932183039478831e-05 0.0017066413850672 2461.910447759319 0.0002226493122151 0.0041267766015837 1853.48724436918 0.0008136106120736 0.0122278464449421 1502.911375968483 0.0002508657782741 0.0056486193722898 2251.6500302077065 0.0003398039374349 0.0086313076186733 2540.084639344767 0.0016519653161907 0.0266239381161026 1611.652366739474 0.0005977455886798 0.0141065685903269 2359.961973367803 +r_2383 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:1), ER membrane 9.689223342326931e-05 0.0020198761423348 2084.6625895299 0.0003690968622715 0.0052750976279691 1429.190591191994 0.0001410220368679 0.0024220967869811 1717.5307070973795 0.0002474803640905 0.0047167594600856 1905.912607417922 0.0006461183431615 0.0109122372372612 1688.8914163722247 0.0004830569436087 0.0083768100849264 1734.124764328286 0.000781618149115 0.0143858272415697 1840.5185777552483 0.0018110999045725 0.028171685166115 1555.5014439009433 0.0004820619651097 0.0139932468336099 2902.7900656765228 +r_2384 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), ER membrane 7.065797337176494e-05 0.0017570022376959 2486.6298223011645 3.269391438840333e-05 0.0010110515264362 3092.476215680256 5.624703070878247e-05 0.0019330595667236 3436.731756974053 0.0001681821096954 0.0039745927498868 2363.2672684892964 0.0001256467091247 0.0044219022383957 3519.3140108481925 7.151280745826971e-05 0.0023390093432225 3270.755863678595 0.0003287619668262 0.0095454284596772 2903.446694830554 0.0002494546697605 0.0080011515045547 3207.4570952052013 0.0008976306791919 0.0195337753850922 2176.148369023674 +r_2385 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membrane 6.195616509120854e-05 0.0016490299396761 2661.607504674502 1.6740558908192204e-05 0.0006912820861132 4129.384746974758 0.0001086828038722 0.0026922468344708 2477.1598988516066 0.0001407177353466 0.003716181527946 2640.876445880395 0.000161668458973 0.0056858008936783 3516.951253073167 0.0001004639976687 0.0028552698667675 2842.0826694363386 0.0003614136760638 0.0103632219287235 2867.412777952404 0.0003842364829116 0.0098731469812315 2569.5495925884334 0.0002185590303005 0.0091270862173579 4176.027961327231 +r_2386 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 2.706351356710417e-05 0.0010858010885161 4012.047755085142 2.822633218818921e-05 0.0009100857535185 3224.243757392453 8.639629797790383e-05 0.0022634473138326 2619.8429409690407 0.0001185623171903 0.0033211304777951 2801.168665135908 0.0002212815266874 0.0064189883039692 2900.8243028962224 8.310185286445042e-05 0.0024198186157275 2911.870833583678 0.0003608213490286 0.0102635241991696 2844.4891708321225 0.0003841455504008 0.0096736068054132 2518.2139413871605 0.000669519939429 0.0165566377403282 2472.911823126033 +r_2387 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 2.6129738277838044e-05 0.0010645153390503 4073.960970183929 1.666255130259539e-05 0.0006653039048317 3992.809340836503 7.745202041707519e-05 0.002172647987968 2805.15340499632 2.074033638607007e-05 0.0014234253941983 6863.077665193539 0.0002980905928646 0.0073615745047138 2469.5762566573026 6.650560877198489e-05 0.0023316943455432 3506.011580974239 0.0004453566143529 0.0112928759147759 2535.692869675324 0.0002833055998939 0.0082050320548986 2896.1771521532287 0.000437681748798 0.0137576213516098 3143.293360847184 +r_2388 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:0), ER membrane 5.285261503850602e-05 0.0015125275270577 2861.783709199214 2.760591680368622e-05 0.0009090984170872 3293.128873611108 9.261852214574632e-05 0.0024343592505982 2628.3719435379567 5.930316380410686e-05 0.0023014528503388 3880.826422585326 0.0002548148357398 0.0069775496869385 2738.2823557663623 5.43115862549325e-05 0.0020183247994037 3716.195638127704 0.0003881012038373 0.0103864969196845 2676.234141246996 0.0003211219326202 0.0091058507662818 2835.6365110226184 0.0009107924709976 0.0193099490235679 2120.1261141758728 +r_2389 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:0), ER membrane 2.6376109281337173e-05 0.0010674046216345 4046.861537648604 3.413747231115743e-05 0.001018814730615 2984.4468897075017 8.26247530655584e-05 0.0023605848679689 2856.994762932523 0.0001190041598132 0.0034088489822517 2864.4788447730502 0.0001564531325745 0.0051064287690163 3263.8712213587537 6.715493896095941e-05 0.0023295979527098 3468.989755264564 0.000356096133366 0.010229267959606 2872.6141626174467 0.0001091656069392 0.0046602721908217 4268.993066116954 0.0003415830544466 0.0119191721595818 3489.39211252471 +r_2390 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:0), ER membrane 4.404334912692435e-05 0.0013853556478751 3145.4366557884937 2.767256759132788e-05 0.0009096519911805 3287.197648640222 6.48606063543923e-05 0.002055802010728 3169.5695218995265 7.259202431964303e-05 0.0025753456774832 3547.697838185681 0.0001734468361791 0.0057390052773932 3308.797902468493 6.630324630707445e-05 0.0023251251724093 3506.804420466556 0.0005036816698046 0.0119791878590075 2378.3251559768223 0.000106726441191 0.004660142051319 4366.436282623654 0.0006773290114137 0.0166500266360156 2458.188909000394 +r_2391 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:0), ER membrane 6.958250648539936e-05 0.0017357618670786 2494.537714652281 2.5743779704637783e-05 0.0009035271331612 3509.6910536353653 2.53895073452952e-05 0.0012366192654715 4870.591810441961 7.18160175616143e-05 0.0025479156102653 3547.837511428952 0.0001041244881566 0.0041757440762294 4010.338154025732 6.415426784047049e-05 0.0020328269185954 3168.6542252346253 0.0001787981222796 0.0072562672630214 4058.357644088303 0.0001367952220818 0.0057976031658085 4238.162033420955 0.0002004039860279 0.0086102216164826 4296.432315114304 +r_2392 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:1), ER membrane 0.0001171320237705 0.0022204130790166 1895.649889364266 6.634063269395817e-05 0.0022772965239053 3432.732597548324 6.65965940788871e-05 0.0019895914166569 2987.527281500504 0.0001130277227095 0.0031726049641135 2806.92637881857 0.0001407541638869 0.0049714638667649 3532.0190390668577 0.0003069465379979 0.0068473760855624 2230.804142709566 0.0003623611056304 0.010118788067945 2792.4597620211 0.0013013088437286 0.0237601878332596 1825.86846679524 0.0007449758224926 0.0165022984489978 2215.145505498728 +r_2393 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:1), ER membrane 6.881499583283791e-05 0.0016649374200159 2419.4398326497467 8.27077041816078e-05 0.0025464727349802 3078.8821430574403 0.0001379618540829 0.0028906379404272 2095.2443410108845 0.0002060198342044 0.0043899979537605 2130.8618030458806 0.0001993553403767 0.0059028773826329 2960.9828216676988 0.0001069637957605 0.003884806055919 3631.8887416974994 0.0004274021088952 0.0112287292324094 2627.204919843438 0.0013577651080256 0.0240200721624931 1769.08892565524 0.0007425070598434 0.0171531625345404 2310.168274784838 +r_2394 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:1), ER membrane 5.403914246702989e-05 0.0015289129316288 2829.269418110589 0.0001074151133964 0.0028258021735775 2630.7305222001664 0.0001848532252742 0.0033604971604755 1817.9272530898463 0.000209413851694 0.0044326192516225 2116.6791096986312 8.791444868945683e-05 0.0030002250985916 3412.6644064952925 0.0001031370529816 0.0039191659483462 3799.959214504852 0.0007893627921342 0.015180333326905 1923.1123481081547 0.0009319207543405 0.0191570179192279 2055.6488124125144 0.0010989046987016 0.0214389941202198 1950.942074007908 +r_2395 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:1), ER membrane 5.482568208701875e-05 0.0015381492968056 2805.526968846996 0.0001478369904791 0.0034076406014514 2304.998627479933 0.0001059244433529 0.00251463344513 2373.987878087771 0.0002813017828436 0.0051033912417449 1814.205082582538 5.911173435228713e-05 0.0028517487271773 4824.336078826278 0.0002213812820149 0.0057626992496536 2603.065262429893 0.0004605532900493 0.0113005483874446 2453.689644956107 0.0008928229039874 0.0191753939015936 2147.7264769927847 0.0010712823393995 0.0212917268255461 1987.499097341606 +r_2396 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:1), ER membrane 6.428003578247578e-05 0.0016116431186341 2507.221875370373 0.0001022966285925 0.0027974428060558 2734.6383204845315 0.0001317042398585 0.0028263206617566 2145.960270369438 0.0001697110542541 0.0039209509900481 2310.368648217985 0.0003318281923441 0.0071391315610376 2151.454193992218 0.0003785579279796 0.0076011653938804 2007.9266162636688 0.0007261129061268 0.0143533687350641 1976.7406162253328 0.0008842040917844 0.0195173096041954 2207.330839739279 0.0011770731424434 0.0214634969152958 1823.4633126315707 +r_2397 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:1), ER membrane 0.000136298642251 0.0023532347088095 1726.5283571022403 0.0002150833235742 0.0041046896951218 1908.4183873066424 0.000109075695074 0.0025619773860913 2348.8068394642173 0.0003065343465361 0.0054603663043062 1781.322832500984 0.0001737778788353 0.0055909226060296 3217.2809585998684 0.0006214803923255 0.0096901521863429 1559.2048125737867 0.0006319709282103 0.0132567621980713 2097.685448223424 0.0020971581217083 0.029901268643473 1425.7994346709556 0.0012275540420684 0.0221896148292656 1807.6283461928952 +r_2398 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:1), ER membrane 0.0001424319309823 0.0024860731841235 1745.4465209992877 0.000257134417326 0.0044404138758832 1726.884297348755 0.0001470937591666 0.0029789766409773 2025.22299916324 0.0002307399988013 0.0044309474197397 1920.320465787388 0.0002365034332036 0.0063715321216505 2694.0548115278725 0.0005144491015718 0.0088831296649717 1726.7266358965198 0.0006487702820615 0.0131392621838473 2025.256480937261 0.0011913125831882 0.0224746965302258 1886.549075984556 0.0022114815208196 0.0299305532742197 1353.416385913368 +r_2399 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:1), ER membrane 0.0001292821632792 0.0022939044631221 1774.3394795830682 0.000164350757329 0.0035804408853087 2178.536286353279 0.0002960628333767 0.004182120986343 1412.578856536517 0.0003782321079615 0.0058814591938959 1554.9867581556716 0.0003541790960133 0.0080186050533095 2263.9972667974985 0.0006005932558587 0.0092759597134012 1544.466179550815 0.0011223530405131 0.0178706671498339 1592.2500768263617 0.0018335653209806 0.0280538233651281 1530.0149410615732 0.0009658522451878 0.0201896752868082 2090.348227422886 +r_2400 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:0), lipid particle 3.544529537095945e-05 0.001245851858453 3514.858164995879 3.261693508814996e-05 0.0016153739557152 4952.562070438614 7.992543505453746e-05 0.0022914582996484 2866.9950912182403 0.0001467287833065 0.003785470234785 2579.909782851747 0.000153920026639 0.005411089277467 3515.5199720412584 0.0001240746932274 0.0043960278929926 3543.0495765426635 0.000302590656209 0.0094987577264958 3139.1444288135085 0.0005536709844168 0.0159101484111587 2873.5745341460683 0.000443580385654 0.0139492034796643 3144.684465499474 +r_2401 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:0), lipid particle 2.543922023228409e-05 0.0010390571572157 4084.4693655237934 7.732579996638932e-05 0.002447023702864 3164.563061652992 5.445771976673152e-05 0.0018445637526647 3387.1483429088385 4.0679296932775536e-05 0.0020191759531548 4963.645159579857 8.733402307958928e-05 0.004046812502029 4633.718176868024 0.0001101169274645 0.0037865362821771 3438.650504844238 0.0003247039935117 0.0094488081643369 2909.97596369128 0.000366664564981 0.0129596927466361 3534.4819173640067 0.0002618912838037 0.0106623974792519 4071.306736287513 +r_2402 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:0), lipid particle 3.167492883591517e-05 0.0011358121225053 3585.8395401269945 5.131393579489096e-05 0.001982189684164 3862.86815356964 9.649498398687862e-05 0.0024815603063432 2571.6987596792137 1.505217951707098e-05 0.0004945061914938 3285.2796562320336 0.0001376357763534 0.0049768267993001 3615.939787718998 0.0001697955605196 0.0051743781116835 3047.4166084477984 0.000309834695259 0.0095848091500802 3093.523513261199 0.0004661852332993 0.0145191742750848 3114.464645807893 0.0007123444747239 0.0176409890160997 2476.468849279156 +r_2403 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:0), lipid particle 2.6538789967685856e-05 0.0010817159519435 4075.9806805837625 4.520549935064985e-05 0.0018400839472551 4070.4869400556354 6.413305706742677e-05 0.0020425736818578 3184.899917854129 0.000141788477357 0.0036264269512847 2557.631634728653 0.0003251927095565 0.0078719548708215 2420.704597454084 0.0001726315236277 0.0052338558862683 3031.807734926933 0.0001216431438035 0.0060619085689779 4983.354079346783 0.0004495100849115 0.0141694257033485 3152.193060615581 0.0003403347540477 0.0120365169133189 3536.6699316371323 +r_2404 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-16:0), lipid particle 2.246925588290598e-05 0.0009450322066926 4205.890090964765 8.077886330887101e-05 0.0025487665571867 3155.2394435672286 1.6806356776271542e-05 0.0009840781905006 5855.392715987547 0.0001283043290592 0.0035187178853409 2742.477912584464 8.147738752028828e-05 0.0040279234360389 4943.608967624248 8.400352556541534e-05 0.0034078392640486 4056.7812375861927 0.0003180037272503 0.0096155110607871 3023.7101759559405 0.0002654529142802 0.0108008413673673 4068.835106463981 0.0002659720188805 0.0107920500391653 4057.588495432417 +r_2405 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-16:0), lipid particle 4.43195093798725e-05 0.0013996563116309 3158.1042552483723 6.443181170382036e-05 0.0022765229239329 3533.22817368173 4.3811346450666215e-05 0.001682035068135 3839.268144906537 5.1207153508959016e-05 0.0020700887966491 4042.577364287549 0.0002404219765256 0.0069175947694935 2877.272231706597 0.0001320696360936 0.0044028078311406 3333.7017965411706 0.0002449757125112 0.0083595894053152 3412.4155899466155 0.0002742091859756 0.0111924378790979 4081.71514724222 0.0006998077336082 0.0174339384048216 2491.246890761321 +r_2406 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:0), lipid particle 1.5291821995689695e-05 0.0007564253327574 4946.60043107135 6.126858980036515e-05 0.0021644451042648 3532.7157215750203 7.062719482091134e-05 0.0020889937888118 2957.775392480005 5.312660763096414e-05 0.0021456345185708 4038.719229872933 0.0001615918156392 0.0056881895268002 3520.097539777324 0.0001043028850289 0.0040544320896717 3887.171566296138 0.0003022676565614 0.0095547271552575 3161.0153940879377 0.0002761319381993 0.0112504596733344 4074.305836079572 0.0003527905756652 0.012450791143568 3529.230087875966 +r_2407 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:0), lipid particle 4.4422380466540735e-05 0.0014003723835038 3152.4028401822866 9.386847518606232e-05 0.0027084016929237 2885.3155306456424 7.098850955060644e-05 0.0021635829240586 3047.793139699992 7.287023831967221e-05 0.0025436564335275 3490.665726066158 0.0001542511620347 0.0049169508828673 3187.626477498409 0.0002696152558855 0.0065822693412953 2441.3564134850017 0.0002315485779342 0.0081769568242187 3531.421741895556 0.0002760617600216 0.0112256255531047 4066.345716344712 0.0001741182992815 0.0086297511559565 4956.257436216859 +r_2408 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:1), lipid particle 8.177913468100706e-05 0.0018809747514444 2300.066830960643 0.0001625075923556 0.0035737155815173 2199.106841540984 0.0001430119913715 0.0029692201466016 2076.203623295064 0.0001709161095248 0.0040698004672832 2381.16844491552 0.0002455402707229 0.006972896879275 2839.8180301518764 0.0002990049384388 0.0069550560616932 2326.06728772024 0.0005404651374876 0.0125227329620721 2317.0288134188604 0.000455426216836 0.0143014020232175 3140.2237057352872 0.0006955951007069 0.0173250644998478 2490.6823642433133 +r_2409 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), lipid particle 3.609501240018576e-05 0.001243627335331 3445.427089878648 0.0001618449756773 0.0036110802825385 2231.1970250699706 0.0001790835311649 0.0033671344211882 1880.2032768083843 9.40335175133078e-05 0.0029929826733756 3182.8892000686005 0.00023912644588 0.006833460597589 2857.6766456924224 0.0001770500429414 0.0052911155803683 2988.4859062799987 0.0003199877758957 0.0092846485631144 2901.563516644969 0.0003515450733832 0.0123796051589738 3521.484468501449 0.0008741551544976 0.0193522411782428 2213.82223495154 +r_2410 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), lipid particle 9.8839602934409e-05 0.0020676494495165 2091.9240750983395 0.0001161020350407 0.0030176839242535 2599.165400669946 0.0001506295470206 0.0030084950041858 1997.2807883257096 0.0002608105856968 0.004978598219557 1908.8942292183808 0.0002505723005568 0.0068533015622348 2735.0595205471427 0.000311517431513 0.0069853893984372 2242.375126332258 0.0007362018894569 0.0142484693866028 1935.40244743367 0.0007259303944366 0.0177938799813031 2451.182664022784 0.001383904993295 0.0239249833256613 1728.802442478105 +r_2411 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), lipid particle 7.367658940750446e-05 0.0017496710826787 2374.7992364323177 0.0001259970164883 0.0031441822740879 2495.4418459416543 0.0001099989805193 0.0025879307017072 2352.686078987656 8.439027677905227e-05 0.0028694862327824 3400.2569280525668 0.0001253062998301 0.0049197565269928 3926.18450441936 0.0001423733155476 0.0045011783119674 3161.5322679341275 0.000460965286309 0.0114440790843999 2482.6336004676714 0.0002637071113004 0.0105391878444899 3996.550488350047 0.000787079236535 0.0184804570713601 2347.9792393859943 +r_2412 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-16:1), lipid particle 5.980005705736008e-05 0.0015856065883126 2651.513504061877 0.0001141178121928 0.0030245200399658 2650.348777151978 0.0001860293251067 0.0034284713542399 1842.9736022924 0.0001996286090379 0.0043639248680736 2186.021777691902 0.0002807661840943 0.0074163824037441 2641.479930236991 0.0003382407894695 0.0072465145704672 2142.412977994425 0.0009496175953341 0.0165073061965902 1738.310903009546 0.0008144880352414 0.0189473476097302 2326.289250413964 0.0007866562257696 0.0184977754125257 2351.4433378352446 +r_2413 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-16:1), lipid particle 5.309594433483291e-05 0.0015161428424809 2855.477685677529 0.0002109401096285 0.0041156795618811 1951.1128391504085 0.0003053771453572 0.0042993323780358 1407.876274764056 0.0001557239106007 0.0038700607819712 2485.2065216193328 0.0003247886260839 0.008009543513982 2466.078818878007 0.0002984762513409 0.0069400001073485 2325.143148297121 0.0008577459752347 0.0156367237887523 1823.001709156792 0.0009970466592469 0.021227409796493 2129.028726953069 0.0015069898026475 0.025596292813758 1698.5047124267044 +r_2414 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:1), lipid particle 8.900144833091478e-05 0.0019517544996575 2192.946897224351 0.0001750474316492 0.0037156652980975 2122.661991146432 0.0001454854627992 0.0029674362710802 2039.6788888622573 0.0002259385028443 0.0045670642741043 2021.3749390253429 0.0002000949719602 0.0062063107069599 3101.682489150416 0.0001055388833972 0.004053987244073 3841.226203630391 0.0008583780850227 0.015632296446511 1821.143470373692 0.0008095421598264 0.0187497556949805 2316.0937904704774 0.0014738014644846 0.0252235016754514 1711.4585840278596 +r_2415 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:1), lipid particle 8.37141165383361e-05 0.0018702083641324 2234.0418097538463 0.0001736723610572 0.0036901684242055 2124.7873880108214 0.00039404093094 0.0048077628119848 1220.1176158313265 0.0002055198704315 0.0043228966549679 2103.395961612282 0.0004260774030928 0.0090258589109906 2118.36132249067 0.0004355072520934 0.0082503160276822 1894.415302621088 0.0008676021954294 0.0157122009384521 1810.991376142812 0.000811198796846 0.0188512853477881 2323.8798456165487 0.001133933822807 0.0221602345068403 1954.279346918424 +r_2416 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), lipid particle 1.7800465055747332e-05 0.0008839755784968 4966.025189389083 7.915727044755033e-05 0.0024965207749632 3153.87425671459 5.528449902585584e-05 0.0019296873254211 3490.467236609484 9.170164887758108e-05 0.0029443165417771 3210.7563798637216 0.0001886666142092 0.0058759985525969 3114.487731294388 0.0001998195605033 0.0057109450057546 2858.051029322982 0.0001211839703484 0.0060396156717781 4983.840399363802 0.0002772803307216 0.0112079567482855 4042.1030655567 8.882245617658632e-05 0.0061726579651165 6949.433995435551 +r_2417 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), lipid particle 6.190180964828757e-05 0.0016524707909017 2669.5032023954755 9.175961313076362e-05 0.0025865632110807 2818.847118933163 4.1349834219257e-05 0.0016721759401583 4043.972537572062 9.155820880474948e-05 0.0029455028393936 3217.082201416833 0.000161152251512 0.0056857795065703 3528.203579671927 4.293403386287392e-05 0.0023657357996312 5510.164284090159 0.0003617700333589 0.0104231419453969 2881.151279618008 0.0001838453838507 0.0091715912995253 4988.75256338831 0.0004417126420793 0.0139297936427262 3153.587268218384 +r_2418 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), lipid particle 5.3672090373226925e-05 0.0015358256145407 2861.4976682683746 9.58110682635922e-05 0.0026055329891987 2719.448844918953 8.632606137402389e-05 0.0023790353655579 2755.871549902307 0.0001218981643829 0.0035009974884103 2872.067439351285 0.000242629373018 0.0069740624988066 2874.3685943940222 0.0001058260074457 0.0040419252491336 3819.40635075366 0.0001824688607375 0.0074037752215469 4057.5554599398415 0.0006801454603245 0.0173395060670219 2549.3820187741585 0.0001774710604652 0.0087814027023818 4948.075860571256 +r_2419 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), lipid particle 4.444067638383669e-05 0.0014012198458094 3153.0119697258 5.226446111852825e-05 0.0019929841382756 3813.2683196634352 1.4686848423865723e-05 0.0009677754086431 6589.401488412818 8.642363451992354e-05 0.0028755527494686 3327.275884012619 0.0001562721309279 0.0054581210195323 3492.702753281324 0.0001323127430598 0.0046477530725516 3512.702529679816 0.0002329293222187 0.0082390928375149 3537.16430333183 0.0009137620751227 0.0199891540460792 2187.56660954584 0.0002104191036224 0.0091302075261447 4339.058274160543 +r_2420 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:0), lipid particle 3.418747628229275e-05 0.0012070270941824 3530.6118656310773 9.193957220015992e-05 0.0025899824817678 2817.048654663355 6.81043451935411e-05 0.0021506134677858 3157.821225171748 4.060980487873854e-05 0.0020148601949882 4961.511637410332 0.0001610464807392 0.0056866600377983 3531.067559933566 0.0001647679554699 0.0051887516315299 3149.126671343324 0.0002932150449408 0.0092738330935625 3162.8094306799194 0.0003301539314955 0.0115901549735716 3510.5306549185307 0.0003526497011922 0.0124623478440452 3533.917029253386 +r_2421 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:0), lipid particle 5.296215431833964e-05 0.0015265188992872 2882.2824881930133 0.0001438244496322 0.0032649915895815 2270.1227767114387 8.274117367345864e-05 0.0023611479036978 2853.655319195996 8.055593512020325e-05 0.0028472064898341 3534.4465750234904 0.000376682404918 0.0085470544093821 2269.034682212385 9.902758152707148e-05 0.0040239301773064 4063.4438559992254 0.000353876743304 0.010209966702694 2885.175953459873 0.0004682183974121 0.0145076443512309 3098.4780673751043 0.0005280614675461 0.0152205527812056 2882.3449004779327 +r_2422 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:0), lipid particle 8.863692362847539e-05 0.0019790441029569 2232.753599676068 5.584805658005057e-05 0.0020097163771467 3598.5430831708754 5.531974057530009e-05 0.0019292450454656 3487.4441300742915 0.0001009161576049 0.003183487192352 3154.5862108755555 0.0001962691905209 0.0062113193453102 3164.694024988326 0.0002997941599928 0.0069609456598282 2321.9083587199684 0.0002422529575046 0.0085489513543515 3528.9358042977283 0.0005914725318765 0.0160995580062576 2721.9451688109407 0.0002647183038728 0.0107837888854707 4073.684640503274 +r_2423 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:0), lipid particle 5.188744746564179e-05 0.0014977615532937 2886.558554042419 9.16713908666214e-05 0.0025872279945173 2822.2850881380027 9.626808011969736e-05 0.0025488871669412 2647.6971014400724 6.087360245171527e-05 0.0024658873209522 4050.831923259599 0.0001185910988279 0.0048191304103893 4063.6527176290647 8.15372625854002e-05 0.0033922051359157 4160.312755610167 0.0006272868305013 0.0133833215093689 2133.5250253338268 0.0005254273751713 0.0146420031364518 2786.6844835933425 0.0002650968205456 0.0107871800288235 4069.147267258143 +r_2424 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:1), lipid particle 8.690349989216957e-05 0.0019417693254867 2234.39715074314 9.689731642965714e-05 0.0027338723007313 2821.411780496562 7.475252147798173e-05 0.0021718571168902 2905.396465495712 0.0001819732609279 0.0042728800981254 2348.0812930079114 0.0003228030762594 0.0080327608710728 2488.4400000622845 0.0002328255841277 0.0061832372241227 2655.737876612033 0.0004984394962782 0.0120598550439498 2419.5223560728605 0.0004785983401079 0.0145619684857169 3042.62828877157 0.0006204488716154 0.016524142225173 2663.2560684893074 +r_2425 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:1), lipid particle 7.08723830320387e-05 0.0017696184117875 2496.908296405873 4.868791478858111e-05 0.0019707815065912 4047.783757322547 0.0001235301957158 0.0028979378123822 2345.934769703715 8.094636686078263e-05 0.0028533647635911 3525.006586766919 0.0003236487478505 0.0079445986405181 2454.697783718116 0.0001241882157329 0.0043584059800549 3509.516546582504 0.0004252308995173 0.0111622449823641 2624.984448456724 0.0003970964715638 0.0130763181635891 3292.982713266872 0.0002516756526521 0.0102957566892463 4090.883079372906 +r_2426 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:1), lipid particle 7.964263956051564e-05 0.0018743010973556 2353.388973166205 0.000129490843689 0.0032284252962944 2493.1687865493377 0.0001654187063114 0.0033637876534707 2033.4989485032868 0.0002943705263155 0.0053709343562511 1824.548953143048 0.0005435872608567 0.0101785626125969 1872.479976178131 0.0001334581176281 0.0046935495136034 3516.8707584222616 0.0006626489032593 0.0139844906117816 2110.392176459705 0.0010084157841494 0.0211224003184171 2094.612227458556 0.001105516561454 0.0216600664486291 1959.2710958702944 +r_2427 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:1), lipid particle 7.092594913723683e-05 0.0017305367091293 2439.9204102025947 8.297274445545119e-05 0.0025576597961444 3082.5300680727096 8.233739569365721e-05 0.0023757156607813 2885.342244270609 0.0001428819821444 0.0037881523944862 2651.245690766876 0.0003957588229924 0.0088515069496132 2236.5911851778183 0.0003005697096524 0.0067349681351555 2240.7341521346534 0.0005441680547176 0.0124976269924803 2296.6484129549785 0.0003262337931157 0.0113910045255968 3491.6690931392063 0.0011168444651156 0.0217571932499815 1948.09518510068 +r_2428 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:1), lipid particle 8.702874220056368e-05 0.0018821017951819 2162.62093142118 0.000159503460175 0.0035642519445476 2234.592240591801 0.0001241943459382 0.0027829063229056 2240.7673246973227 0.0001377871003266 0.0036852721181309 2674.613305160075 0.0004328303262461 0.0091362419431281 2110.813727486316 0.0003213161971161 0.0070434440058505 2192.0600545709467 0.0004212165990426 0.0109292586932124 2594.688508964677 0.0004980460186008 0.0146201296854113 2935.497753095855 0.0004245552626202 0.0134226709985297 3161.5839397890622 +r_2429 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:1), lipid particle 8.747334929044987e-05 0.0019553081251327 2235.318689627685 0.0001699988082055 0.0036558834021143 2150.534724745606 0.0001273878032562 0.0028533869226316 2239.921601357536 0.0001367090953394 0.003564723053618 2607.5244260572595 0.0005197566423102 0.0101335326725533 1949.668719482237 0.0003622957602415 0.0077152839747142 2129.554033304088 0.0002999558211925 0.0092372907671404 3079.550425264163 0.0008065035500463 0.0185102781842223 2295.126683962942 0.0005064568807166 0.0146521774700377 2893.075013474844 +r_2430 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:1), lipid particle 9.766075493143808e-05 0.002077510279636 2127.2723942125 0.0001128353268674 0.0030007439782159 2659.401148136959 6.89556787086907e-05 0.002165840921477 3140.917415412282 0.0001279486904911 0.0035144100187831 2746.7338706573787 0.0002397767797858 0.0067571869379286 2818.115642375032 0.0003808430541914 0.0077642063725714 2038.6892414398003 0.0005441641044295 0.012669780119546 2328.3013371175007 0.0004965427716774 0.0146178952097775 2943.9347511584137 0.0002559558239951 0.0099356434145754 3881.780558649599 +r_2431 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:1), lipid particle 6.982561114197214e-05 0.0017430090879607 2496.2317686225288 9.750822189548413e-05 0.0027971681316492 2868.64848653223 0.0001813000219724 0.0033916537940022 1870.7409723962555 0.0001417026191244 0.0037681680797961 2659.208491048604 0.0004070978143794 0.0089594729507738 2200.8157829171573 0.0001591622599137 0.0050159298720667 3151.456805641807 0.0007620355735301 0.0148637481011046 1950.532050918208 0.0006552734252907 0.017239794327867 2630.9314039734027 0.0009719756956201 0.0205011439592713 2109.2239293277776 +r_2432 CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane 0.0004994981556236 0.0021781550240008 436.0686820317235 0.0008348980533774 0.0038445903268504 460.4862008358713 0.0015042641939077 0.0036694915412649 243.93929976705192 0.0021698864380397 0.0048061929656173 221.4951382413944 0.0032847329654296 0.0098928534332917 301.17679389495163 0.0037495704634911 0.0091123437281239 243.02366942691208 0.0047500279760186 0.0159963054291212 336.76234139843706 0.0060787860347827 0.0240156212666219 395.0726531449677 0.0054093744088832 0.0166300370028541 307.4299493032753 +r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 0.0007068551832833 0.0024439264005371 345.7464072322389 0.0012156696441199 0.0045829778449033 376.9920444317044 0.002162287960236 0.0037286058889149 172.4379896425956 0.0032530098323299 0.0058658267223656 180.31998133139 0.0050701055681752 0.0121582151667111 239.802012073034 0.0052680739111389 0.0086990647555935 165.1279936904453 0.0068707529889063 0.0176471252048454 256.844122228506 0.0076479884271525 0.0204074272859092 266.833919537027 0.0094898646241219 0.0267382612619893 281.7559819981441 +r_2434 CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane 0.0003249711707567 0.0020657782811138 635.680474764479 0.000583057109063 0.0039410188090133 675.9232925478274 0.0008153566524349 0.003187111984626 390.88562963313296 0.0012808745014762 0.0050758217830093 396.2778380832364 0.0021197546240211 0.0104856801454728 494.6648082116964 0.0019298772761951 0.0069491716062157 360.0836017882194 0.0028236581777353 0.014395763448019 509.82670500028087 0.004069378732126 0.0235129058894476 577.8008742175549 0.0043242451904763 0.0238674621527282 551.9451627140354 +r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 0.0001805325524688 0.0020404544007549 1130.2418166981474 0.0002699898643117 0.0034401808384593 1274.1888838047512 0.0002299287414879 0.0027385627129446 1191.0484505863674 0.0003742510648066 0.0043079619220393 1151.0887548883843 0.0011529280949974 0.0110578820378059 959.1128957465633 0.0009331753534264 0.0091145671772644 976.726093739808 0.0012250220353824 0.0140252672958154 1144.8991847266293 0.0020639418104756 0.0228908522909844 1109.0841890406243 0.0021012626223491 0.0216833736323907 1031.921160247405 +r_2436 CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane 0.0005797071853617 0.0022267342376912 384.1136169981761 0.0008922837197175 0.0035637828110909 399.4001831860224 0.0016733567823015 0.0031604834773431 188.8708678729145 0.0025869300655395 0.0051816614571194 200.30156694779868 0.0039025280471449 0.0103887395716349 266.2053788245109 0.0043210314367132 0.0082793403769726 191.60565013778904 0.0052952362750913 0.0153219193064705 289.35289211823084 0.0069368905262029 0.0250224197944056 360.71521814979945 0.0079065362806137 0.0241974296458404 306.0433644650549 +r_2437 CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane 0.000215943076796 0.0020827380950389 964.4847734599706 0.0003328280233803 0.0035965276483057 1080.5964028443505 0.0004173732241922 0.0032121358343385 769.6075474307567 0.0004541711085099 0.0040502946482932 891.7992739743493 0.001221143522501 0.0104712117085161 857.4923025484852 0.0010072284298134 0.0083843619083602 832.4191077403419 0.0014126411446171 0.0134471069269727 951.9124498258 0.0023204568840716 0.0225005505482299 969.66035881473 0.0024522999774819 0.0228925067885527 933.511682859418 +r_2438 CDP-diacylglycerol synthase (1-18:0, 2-18:1), ER membrane 0.0001551621424122 0.001714392521117 1104.903873112334 0.0004467011445029 0.0042397798931728 949.1311910315442 0.000435364193981 0.0033870575383121 777.982568419374 0.0006136270739469 0.0047970622645372 781.7553149475725 0.0009972103266846 0.0090100466119914 903.5252013430628 0.0011689622978005 0.0088078948295791 753.4798039382312 0.0017354373314274 0.0146658897714231 845.0832251810723 0.0024074387198138 0.0224065437928928 930.721251946374 0.0022127644113463 0.0208251227658211 941.136013352194 +r_2439 CDP-diacylglycerol synthase (1-18:1, 2-18:1), ER membrane 0.0002112764278812 0.0022327343425126 1056.7834589516108 0.0003616992433439 0.0039863250471118 1102.1104192139424 0.0003478034470501 0.003444780630193 990.4388985816944 0.0005285679417489 0.0051589242912887 976.0191422541308 0.0006052079695133 0.0071379877270251 1179.4272525467768 0.0006351035037967 0.0070632271530257 1112.1379603168764 0.0015973038438057 0.0160168437781461 1002.7424550600226 0.0021305572906567 0.0220262252247186 1033.8245923407528 0.0015607953888178 0.0183511888334794 1175.758780744388 +r_2440 CDP-diacylglycerol synthase (1-16:0, 2-16:1), mitochondrial membrane 5.236578011949228e-05 0.0010249704919274 1957.3287929418268 8.051001170339299e-05 0.0017133983719608 2128.1805029083816 9.34012219043938e-05 0.0017015817287902 1821.7981457801468 0.000118771785158 0.0023266367582085 1958.91368906634 6.252801962731268e-05 0.0023078763568145 3690.947467343906 0.0001652166948582 0.0035112955935244 2125.266817943368 0.0005185828024459 0.0083994347537237 1619.6901852715523 0.000337344062811 0.0081260894601414 2408.84318295939 0.0005200860958881 0.0101876812620228 1958.8451494026187 +r_2441 CDP-diacylglycerol synthase (1-16:1, 2-16:1), mitochondrial membrane 5.254803379808145e-05 0.0010218497331569 1944.6012710645907 0.0001179094349285 0.0020637890297327 1750.317123463315 6.35417705851757e-05 0.0013870688311852 2182.924426580013 9.536202261811258e-05 0.0020579161061945 2158.0038360088784 0.0002225675287156 0.0044819042014068 2013.7278008474864 0.0001839338394386 0.0036766544628147 1998.9005144652688 0.0003099879659908 0.0064592360774181 2083.705429264533 0.0004614106025603 0.0097223965034603 2107.1029684864043 0.0002449093444222 0.0069562843748639 2840.3507392802003 +r_2442 CDP-diacylglycerol synthase (1-18:0, 2-16:1), mitochondrial membrane 4.670021003548938e-05 0.0009564670269543 2048.100053998627 9.521862590359636e-05 0.001865163596713 1958.8222146803944 5.473861635508189e-05 0.0012885104579609 2353.933189692993 0.0001190385096681 0.002329734257015 1957.126532842766 0.0001616885768872 0.0038026363047164 2351.827431425882 0.000148987464211 0.0033283903245078 2234.006963023577 0.0002155786128684 0.0053850641663843 2497.958445289355 0.0002495757201236 0.0072011329453566 2885.3499618426026 0.0003609316877739 0.0085000814820452 2355.038853603986 +r_2443 CDP-diacylglycerol synthase (1-18:1, 2-16:1), mitochondrial membrane 5.2380337500109765e-05 0.0010252502012632 1957.3188150249748 0.0001221965019381 0.0020980353999074 1716.935727807247 9.202526857443068e-05 0.0016784096570845 1823.857385134435 0.0001555949731497 0.0026642117532481 1712.273667532656 0.0003639098835194 0.0057443050565641 1578.4965775070832 0.0001635822953167 0.0034804325009797 2127.633980339694 0.0002952244607753 0.0062996611080757 2133.854725835182 0.0004993986468873 0.0101828166482908 2039.0156664938256 0.0002247559615726 0.0065404471876404 2910.021670560628 +r_2444 CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane 6.640330017407991e-05 0.0011415222159249 1719.0745233029108 9.763726399713722e-05 0.0018713130197401 1916.597150648368 6.195895162157319e-05 0.0013842668840044 2234.16769938124 0.0001093389017337 0.002229553394094 2039.1218118526992 0.0002375154988664 0.0046525419273971 1958.8371915105697 7.847644683144275e-05 0.0023693201137269 3019.148049370729 0.0003581830971794 0.0069429672479605 1938.3849496623657 0.0004589685251061 0.0097754875668542 2129.8819052117547 0.0005210749941658 0.0101967048428656 1956.8593690027708 +r_2445 CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane 3.588212530193559e-05 0.0008445754571803 2353.7498129600367 0.0001023524952802 0.0019319145020389 1887.510897266704 9.276026017453898e-05 0.0016888245888786 1820.6337344256235 6.913143764091042e-05 0.0017357550065017 2510.804151821321 0.0002908221501072 0.0051338560893135 1765.2906036970037 0.0002385305078244 0.004210506237611 1765.185625945102 0.000518842791608 0.0084035872067713 1619.6788974798046 0.0006254050649566 0.0114023757020397 1823.198490218494 0.0004009553908843 0.0089576194528606 2234.0688407018424 +r_2446 PS synthase (1-16:0, 2-16:1), ER membrane 0.0003191739645368 0.0003408797828838 106.80062309546808 0.0005242656690963 0.0004848784478778 92.48716375298324 0.0011623987808196 0.000787301576537 67.73076413430982 0.0017686915647961 0.0012163815385752 68.77295978484995 0.0024611843748385 0.0018561362582284 75.41638396555372 0.0029024884653696 0.0019777668416191 68.1403859211283 0.0033443691967042 0.0029390966665804 87.88194405919023 0.0039218532433732 0.0034814960953884 88.77170764283886 0.0043280472071273 0.0040268922020633 93.04178095451336 +r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 0.0003038419827949 0.0003492604509378 114.94805547445895 0.0004873252449262 0.0004409633934096 90.48646627704612 0.0011427300809607 0.0008653980386122 75.73074805947476 0.0016603127711516 0.0010290313932373 61.97816526602968 0.0023658426989048 0.0018711598635447 79.09062865468337 0.0028307394838583 0.0018853737014468 66.60357522116593 0.0031659527941119 0.0028038793094501 88.5635223198777 0.0038752006127751 0.0044688883879501 115.32018170150586 0.0043100085088119 0.004038791802841 93.70728142609444 +r_2448 PS synthase (1-18:0, 2-16:1), ER membrane 0.0001628864789106 0.0003493524274175 214.47601406455124 0.0002611960811356 0.0005022175251154 192.27605672024904 0.000558592730994 0.0005694350345135 101.9410033317486 0.0008529312571785 0.0009975392983379 116.9542433745274 0.0012073749514156 0.0015579948024189 129.03984802667387 0.0014199830154223 0.0017154305416498 120.80641268372368 0.0016890073547559 0.0029396054827379 174.0433796490282 0.0020240667563976 0.0040336169140786 199.28280039822323 0.002147312286132 0.0027680484251608 128.9075856845651 +r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 3.056199644452912e-05 0.0003656616185532 1196.4585468651967 3.210750802976104e-05 0.0004372043792912 1361.6889198812682 5.388421779309489e-05 0.0006211871602097 1152.8183680702389 9.091404425675042e-05 0.0009618215160197 1057.946023502669 0.0001711743390992 0.0019144986062505 1118.449538829606 0.0001109818840455 0.0012253290193475 1104.0802108253004 0.0001614426468967 0.0020895673638753 1294.309405873626 0.0002353203077454 0.0032381452933351 1376.0585834514625 0.0004068615334888 0.0043268027655647 1063.4583044659614 +r_2450 PS synthase (1-16:0, 2-18:1), ER membrane 0.0003906589099147 0.0003484077793259 89.1846494431717 0.0006254967203432 0.0004435446834507 70.91079281877087 0.0014279678411365 0.0007627383440928 53.41425220653211 0.0021346358936102 0.0012885801795193 60.36533834067522 0.0030267781091727 0.0020209846785699 66.77016304714533 0.0036056127077867 0.0018863125047652 52.31600445304432 0.0040018598964509 0.0027469868163262 68.64275330484057 0.0046583610747359 0.00355317378128 76.27519044305757 0.0056056356206827 0.0044445329371012 79.28686839191764 +r_2451 PS synthase (1-16:1, 2-18:1), ER membrane 5.357021471569533e-05 0.0003449552214557 643.9310039851891 6.624317634382161e-05 0.000398324803815 601.3069206519518 0.0001667348308224 0.0008188733185376 491.1231291615954 0.0001906625734361 0.0008786121150296 460.8204427305185 0.0003622690200926 0.0019026939483693 525.2157493021725 0.0003220936650328 0.0017214334627442 534.4512015064614 0.0004559438020056 0.0026285754416703 576.5130329894486 0.0005567978593046 0.0035660260217319 640.4525380512914 0.0005301280280313 0.0036452321517136 687.6135497400462 +r_2452 PS synthase (1-18:0, 2-18:1), ER membrane 3.804135213699825e-05 0.0002059560522695 541.4004516134521 7.222127966095756e-05 0.0004000848023918 553.9708023314893 0.0001620839102752 0.0007267890514127 448.4029600338404 0.0002390709373546 0.0010396815355861 434.88411727931 0.0003232902206221 0.0017029546376369 526.7572382361925 0.00038210600335 0.0015542004573342 406.7458882372795 0.0005494282679294 0.0030283008114706 551.1730990621854 0.0005879749472209 0.0037583931506917 639.2097432817553 0.0005429689472344 0.003325810349567 612.5231224560121 +r_2453 PS synthase (1-18:1, 2-18:1), ER membrane 2.743633300009194e-05 0.0003433797136427 1251.5510496303018 4.105888611734075e-05 0.0004805773378505 1170.4587807790904 6.641209218019052e-05 0.0006898856431043 1038.7952260750092 9.38964667889932e-05 0.0010061452318552 1071.5474886997154 0.0001866491713657 0.0020067162439268 1075.1273253685436 0.0001452873224524 0.001614793524256 1111.4483335489365 0.0002117748780295 0.0024806480168109 1171.360852567818 0.0003669225005592 0.0042681107981842 1163.218606566386 0.0003357101140102 0.0039596987575544 1179.4993931679858 +r_2454 PI synthase (1-16:0, 2-16:1), ER membrane 0.0001803241910868 0.0021580201969464 1196.744698501018 0.000310632384281 0.0038200865327619 1229.7772949859211 0.0003418654130881 0.0036132101598977 1056.9101235656372 0.0004011948732436 0.0046938308563083 1169.962820900318 0.0008235485905911 0.0097595173509948 1185.0566514830432 0.0008470819981215 0.0089499836927606 1056.5663905746894 0.0014056587793144 0.0157943681795326 1123.6274700490171 0.0021569327914095 0.0238804300957411 1107.1476214210588 0.0010813272017559 0.0161196437745203 1490.7276676610354 +r_2455 PI synthase (1-16:1, 2-16:1), ER membrane 0.0004030132004883 0.0024170966410783 599.7561961119892 0.0007283443991937 0.0045616847860055 626.308761494612 0.0010195578792752 0.0036395937946334 356.977653610061 0.0015926970611782 0.0057880300827643 363.41060857376254 0.0027042628692703 0.0120401303445107 445.2278098156622 0.0024373344272806 0.0084143972526126 345.22949162954063 0.0037048001947944 0.0173974862492001 469.593104471462 0.0037727878143774 0.0199999677393863 530.1111200362279 0.00517985611531 0.0264304768447837 510.255039066884 +r_2456 PI synthase (1-18:0, 2-16:1), ER membrane 0.0001620846918461 0.0020438404957709 1260.9707138238284 0.0003218610279274 0.0039139722139371 1216.0441539446133 0.0002567639214408 0.0031481984394248 1226.1062308746623 0.0004279432442976 0.0050203512989201 1173.1348410836952 0.0009123796726054 0.0104306248082713 1143.2329239082032 0.0005098942607727 0.0067780233232523 1329.2997871715554 0.0011346508229793 0.0141800259051022 1249.725961319822 0.0020453119757284 0.0232269070062191 1135.6168292099833 0.0021769329043442 0.0238627983152181 1096.1659988508409 +r_2457 PI synthase (1-18:1, 2-16:1), ER membrane 0.0001499705560242 0.0020093301861435 1339.8164542500583 0.0002378823562819 0.003398726233184 1428.7424617383706 0.0001760445236948 0.0026422526981636 1500.9002510887483 0.0002833370205498 0.0041285569332722 1457.1187786402118 0.0009817537558982 0.0108432272241461 1104.4752473827525 0.0008221934693809 0.0089692613891851 1090.894263115316 0.0010635793884857 0.0138794163120971 1304.9722909596092 0.0018286215027302 0.0226069192301156 1236.2820406717135 0.0016944010888603 0.0212357856995365 1253.2915517553083 +r_2458 PI synthase (1-16:0, 2-18:1), ER membrane 0.0001890482754469 0.0022089955125858 1168.4822341609838 0.0002667869993743 0.0035659449546488 1336.6262085527828 0.0002453889411649 0.003118508310173 1270.8430524081662 0.0004522941719292 0.0051079353824436 1129.339199896383 0.0008757499379722 0.0102982117142173 1175.930624449997 0.0007154187289264 0.0082121958969644 1147.8866242832803 0.0012933763786403 0.0152470905824033 1178.8595210337107 0.0022785294514669 0.0249554545507494 1095.2438878805056 0.0023009006599309 0.024023666737034 1044.098389617361 +r_2459 PI synthase (1-16:1, 2-18:1), ER membrane 0.0001623728620803 0.002052566913824 1264.107122043664 0.0002665848470364 0.0035732329487579 1340.3736140595045 0.0002506383933697 0.0031106055254124 1241.0730389671482 0.0002635085350738 0.0039559328079156 1501.254146020931 0.0008588745024083 0.0102428185994304 1192.5861776904876 0.0006851347647806 0.0082263172477245 1200.6860066951335 0.0009566973426115 0.0131793395834172 1377.587142391497 0.0017636590247669 0.0221925409849998 1258.323784436292 0.0019221719494505 0.0226019300242094 1175.85370188501 +r_2460 PI synthase (1-18:0, 2-18:1), ER membrane 0.0001171207902752 0.001698092525222 1449.8642992685818 0.000374479864842 0.0042181099185113 1126.391647329484 0.0002732802837058 0.0033021524071453 1208.3390584810402 0.0003745561365922 0.0046623195602427 1244.7585567976591 0.0006739201060625 0.0088024341280799 1306.1539563657682 0.0007868562944504 0.0086241542416589 1096.0265937355866 0.0011860090634979 0.0143066280916382 1206.283200690159 0.0018194637725929 0.0219604109837552 1206.971598695775 0.0016697954641118 0.0204872637968117 1226.9325337824018 +r_2461 PI synthase (1-18:1, 2-18:1), ER membrane 0.0001838400948811 0.0022032936809993 1198.4837597173243 0.0003206403572266 0.0039523764518326 1232.650963222002 0.00028139135487 0.0033715750409737 1198.1800373829217 0.0004346714749599 0.0050415023868444 1159.842013398389 0.0004185587981476 0.0068584606653167 1638.5895352504494 0.0004898161813442 0.0068337701689535 1395.1703576225384 0.0013855289657762 0.0157695391729761 1138.1601945897123 0.0017636347900975 0.0216386238029998 1226.9333721752837 0.0012250852748076 0.0179002319119224 1461.141708256469 +r_2462 lysoPI acyltransferase (1-18:0, 2-16:1), ER membrane 2.882839662410561e-10 9.93934611473518e-10 344.7762372751642 3.285719362785513e-10 1.1999605781527144e-09 365.2048290379345 2.9820000000000606e-10 5.629743759973429e-10 188.79087055577847 2.4240000000000187e-10 5.3529458088222e-10 220.83109772368644 3.2663975259613576e-10 5.819794963435317e-10 178.1716682424455 2.361928129411056e-10 5.447809889694236e-10 230.6509593521222 3.0600000000000665e-10 5.596665483384492e-10 182.89756481648269 3.0066139772891985e-10 5.722455443896357e-10 190.32890444605053 2.1139999999999958e-10 5.276037463311282e-10 249.57603894566188 +r_2463 lysoPI acyltransferase (1-18:0, 2-18:1), ER membrane 2.8126872126007833e-10 1.6839255925578023e-09 598.689248137457 2.740817794450554e-10 1.1843545878351802e-09 432.11722801610193 3.0600000000000665e-10 5.60023861406884e-10 183.01433379309543 2.5188145148424e-10 5.40360667248999e-10 214.5297575763767 3.288094676923678e-10 5.813204223522218e-10 176.79552429922776 2.3780946769234884e-10 5.371088037358863e-10 225.8567789364625 3.2019053230766045e-10 5.611795793913876e-10 175.2642638577986 2.2980000000000088e-10 5.290065496626148e-10 230.2030242221987 2.2745680615408456e-10 5.334958400454052e-10 234.5481979923709 +r_2464 PS decarboxylase (1-16:0, 2-16:1), mitochondrial membrane 5.015527048541705e-05 0.0002275924390644 453.7757186069892 0.0001329818007281 0.0003608192503947 271.3297973249161 8.774242942920747e-05 0.0004693287342931 534.8937080341159 0.0002256763424564 0.0008580979292797 380.23388714087525 0.0003036411741744 0.0011843729993762 390.0567841618984 0.000413034199867 0.0013997975278965 338.9059618664143 0.0002984349840691 0.0014651118233066 490.9316606686075 0.0005265770788919 0.0020903173745733 396.9632288157583 0.0006350422580295 0.0026096556771432 410.9420505716392 +r_2465 PS decarboxylase (1-16:1, 2-16:1), mitochondrial membrane 2.52305553753852e-05 0.0001726533627096 684.3026645306649 4.415628237642885e-05 0.0002945079825064 666.967341126655 9.66484122682223e-05 0.0005156411594865 533.5226387946934 0.0001016870071039 0.0005898071558865 580.0221411605241 0.0001984259457258 0.0012776779886986 643.9067149333833 0.0001865873276228 0.0010725465489366 574.8228256446776 0.0002387473741768 0.0016157600460187 676.7655776696568 0.0002858956831095 0.0025740396452164 900.342256735153 0.0002679135390478 0.0020667431980151 771.4217076749134 +r_2466 PS decarboxylase (1-18:0, 2-16:1), mitochondrial membrane 3.724832708699908e-05 0.0002164538616654 581.1102902953195 4.896971739284922e-05 0.0002533502403921 517.3610424575683 7.981169523490686e-05 0.0004187979690896 524.732581931789 0.0002281396428301 0.0007624782951997 334.2156083620712 0.0002203302817565 0.000999360270125 453.5737267513244 0.0001966275924112 0.0009828570762529 499.8571483279632 0.0005193805749543 0.0019879976177859 382.76318246226657 0.0003713424787544 0.0018975241006225 510.99031465158544 0.0004570272788084 0.0017997871609649 393.80300573246313 +r_2467 PS decarboxylase (1-18:1, 2-16:1), mitochondrial membrane 7.40571956313605e-06 0.0001921266978592 2594.3015559974674 7.202415538656133e-06 0.0002158167845869 2996.450058020332 1.464536674337826e-05 0.0003715789668058 2537.177616080273 1.1424766795543318e-05 0.000397272628236 3477.2931066835577 4.912891980942719e-05 0.0010763679323717 2190.904942642738 2.3471632731148698e-05 0.0006681247956245 2846.520322116012 4.1812604004477895e-05 0.0012389975054835 2963.2153628864858 6.214023955364995e-05 0.0017887531100288 2878.5745321829463 0.0001458184247431 0.0028656329249764 1965.206337967908 +r_2468 PS decarboxylase (1-16:0, 2-18:1), mitochondrial membrane 9.261950719504068e-05 0.0002432563625472 262.6405278048021 0.0001000115654629 0.0003257908057377 325.75313088000064 0.000206634413731 0.0006144927324486 297.38160326401925 0.0003117503669944 0.000936379731481 300.3620302066483 0.0004805443092129 0.0013129420931641 273.219777654757 0.0003909395940042 0.0014998770514331 383.6595408693224 0.0005975437881463 0.0021654664298329 362.3946014986888 0.0006707638777483 0.0027189307594172 405.34841687424415 0.0007098992668366 0.0029676388162029 418.0366081271015 +r_2469 PS decarboxylase (1-16:1, 2-18:1), mitochondrial membrane 8.883361628032877e-06 0.0001702436676434 1916.432931270756 1.894567109575543e-05 0.0002434698250657 1285.0947524382316 3.72793078960887e-05 0.000434972386338 1166.793084116412 3.239839144735387e-05 0.0004349008419769 1342.3531926999938 8.369310428120517e-05 0.0012035171868279 1438.0123633414175 6.99958609959758e-05 0.0010321435804298 1474.578018961987 0.0001452226455756 0.0015683219686034 1079.9431193303053 0.0001566925511824 0.0026781165752093 1709.1537249212265 6.598481973301203e-05 0.0010290539773409 1559.5313914696642 +r_2470 PS decarboxylase (1-18:0, 2-18:1), mitochondrial membrane 4.813089625324781e-06 8.243433636126044e-05 1712.7114344083686 1.4252730047680373e-05 0.0001955295447336 1371.8743291954502 2.4218328854761565e-05 0.0003795179853917 1567.0692543146808 4.334234256756232e-05 0.000562814969065 1298.5338025689186 5.061163856836598e-05 0.0008029638859773 1586.5202326786457 6.764970125578668e-05 0.0008473386875128 1252.5386982997006 0.0001156198318106 0.0017765140861384 1536.5132938846834 8.397015908239272e-05 0.0015421939395289 1836.5976156073275 0.0001398382299362 0.0024475955083655 1750.3049841817858 +r_2471 PS decarboxylase (1-18:1, 2-18:1), mitochondrial membrane 6.594939788700334e-06 0.0001767676622946 2680.352936618156 1.2342595912322376e-05 0.0002683522135384 2174.1958939979386 1.8614255796507577e-05 0.000398233461526 2139.4003922559423 2.1716029055915687e-05 0.0005201890151622 2395.4149896504896 5.24952169338462e-05 0.0010956765433315 2087.1930955391467 4.644311034668739e-05 0.0010247049195547 2206.3658353318533 7.902412948213361e-05 0.0016871277068528 2134.952599805956 8.956883596715579e-05 0.0022594007999059 2522.530046873058 0.0001038573322892 0.002350716424115 2263.4092098266583 +r_2472 PS decarboxylase (1-16:0, 2-16:1), Golgi membrane 0.0001127763909393 0.0002487382879747 220.55882964774875 0.0002398095825719 0.0003714050758253 154.8749936687801 0.0001652903824945 0.000580935576393 351.4636288123235 0.0004196789415789 0.000941324655988 224.2963758073128 0.0005729444618194 0.0012299820408682 214.6773592962828 0.0006600737101913 0.00165939571134 251.3955162460464 0.0008249095881982 0.002263301753716 274.3696747009112 0.000802939654602 0.0022461069129036 279.7354570832426 0.0011273964135471 0.0029321255391149 260.0793743781309 +r_2473 PS decarboxylase (1-16:1, 2-16:1), Golgi membrane 3.9181405621685074e-05 0.0001855027863532 473.4459711435673 5.880840311086909e-05 0.0002194973513057 373.2414751883677 0.0001415996416323 0.0005862450183105 414.0158912495764 0.0001748169745197 0.000681408516555 389.78395457696286 0.0002701777718058 0.0010926550371035 404.4207744405627 0.0002570562834735 0.0011379099820112 442.6695845108436 0.0003265404311232 0.0015688795681625 480.4549203190454 0.0006923456011901 0.002779201501465 401.418236309692 0.0004190218261051 0.002149421620164 512.9617328393327 +r_2474 PS decarboxylase (1-18:0, 2-16:1), Golgi membrane 4.732062840290904e-05 0.0002115117374116 446.9757578254128 8.749460407553554e-05 0.0002826026626396 322.99438991195245 0.0001579550399013 0.000406235012296 257.1839509203379 0.0001918117295759 0.0005494964275379 286.47696819833754 0.0003238279274472 0.0010202916167941 315.07215107641275 0.0006201636016057 0.0012795203046615 206.3198003476271 0.0003720723311737 0.0017686990271722 475.3642985472095 0.000524351514185 0.0022052901213161 420.57475980471895 0.0005116474814829 0.0018914007788863 369.6687362564945 +r_2475 PS decarboxylase (1-18:1, 2-16:1), Golgi membrane 1.2629212213548674e-05 0.0002349371105065 1860.2673431563228 8.684691898024197e-06 0.0002317504640266 2668.493790544474 1.666717762390746e-05 0.0003537849877756 2122.6448518087445 3.3404351417821784e-05 0.000578046454991 1730.4525621850669 7.425456289313018e-05 0.0013131963712962 1768.5059612918435 3.2070568606620294e-05 0.0007561683554796 2357.826469355336 4.602087527005137e-05 0.0011007964525585 2391.9502749547623 8.977165431411688e-05 0.002156179605979 2401.8490273493567 7.072015264239406e-05 0.0017543092235855 2480.635516238833 +r_2476 PS decarboxylase (1-16:0, 2-18:1), Golgi membrane 0.0001037472268174 0.000250535666209 241.48661501083603 0.0002119286466104 0.0003892423686202 183.6667080386906 0.0003302400346522 0.0006887389638361 208.55707714581973 0.0005839000923703 0.0011603878838625 198.73055322733308 0.0007671874939541 0.0015869404535857 206.85171044779923 0.0020489700376793 0.0021581874635205 105.3303573909234 0.0009271781363251 0.002022172331995 218.09965666467625 0.0009369052621064 0.0024571046119262 262.25753139669933 0.0011651465891871 0.0034096946420488 292.6408293764703 +r_2477 PS decarboxylase (1-16:1, 2-18:1), Golgi membrane 1.957348682929145e-05 0.0001989120491288 1016.232063625898 1.7827061991030518e-05 0.0002157990064057 1210.513580500835 4.656636350814144e-05 0.000504468777582 1083.3329888297524 5.150117421455275e-05 0.0004698121976246 912.23589518056 7.76254519760802e-05 0.0008526611058132 1098.429811495337 9.277763442306083e-05 0.0010163686060852 1095.4888130157683 0.0001224782291452 0.0016648747680418 1359.3230239042389 0.0001024244399729 0.0015256833275593 1489.5696065917286 0.0001654782866496 0.0024475559262069 1479.0798090562662 +r_2478 PS decarboxylase (1-18:0, 2-18:1), Golgi membrane 1.26490235674255e-05 0.000153808519102 1215.9714801874825 2.3307567518694683e-05 0.0002007484334584 861.301520621878 3.027987860208172e-05 0.000286255672829 945.365985745347 6.283235110945872e-05 0.0006025796206065 959.027650512103 8.691560866043742e-05 0.0009918821101223 1141.2013623438752 0.0001079451969456 0.0009870568499562 914.4055297364704 0.0001158930849928 0.0012414666566453 1071.2171970585282 0.0001410820775858 0.001970458904399 1396.6755651157562 0.0001103045956026 0.0004457816200176 404.136942420218 +r_2479 PS decarboxylase (1-18:1, 2-18:1), Golgi membrane 5.1894474476236505e-06 0.0001387787333136 2674.248746409841 1.002633775925678e-05 0.0002411319914705 2404.985721211644 1.383011061628201e-05 0.0002953984653963 2135.908190412958 3.2021762091163745e-05 0.0005939732436071 1854.904929704069 5.399964564735802e-05 0.0010706160669265 1982.6353563839875 3.4906094495313254e-05 0.0008027276451298 2299.677625744108 4.627762943590105e-05 0.0010265515578066 2218.245770839572 9.016245597308456e-05 0.0020097181193182 2228.996645697177 7.706722145325043e-05 0.0019918079002805 2584.5072168441425 +r_2480 PS decarboxylase (1-16:0, 2-16:1), vacuolar membrane 0.0001503931393929 0.0002499606252911 166.2048058176651 0.0001427812062892 0.0003712938919789 260.0439523019838 0.0008879588434059 0.0007398798154884 83.32366088618336 0.0011044004219331 0.0012088059501949 109.45359365936234 0.001549370293862 0.001899282524874 122.58415773158218 0.0017826055325794 0.0019026881383922 106.736353254724 0.0021842540149115 0.0025851186051028 118.3524712535562 0.0025450806841589 0.003207824836755 126.04020205415038 0.0025090863921522 0.0033176243302813 132.22439612513733 +r_2481 PS decarboxylase (1-16:1, 2-16:1), vacuolar membrane 6.728214924130097e-05 0.0002719904600599 404.2535250836301 9.608581435050465e-05 0.0003081024665617 320.6534373927997 0.0002422973862553 0.0005773246957086 238.27111989572663 0.0003843479396681 0.0007631269580422 198.55107294219664 0.0004968028276787 0.0012212831810475 245.82854867266573 0.0007524217978873 0.0014003405493744 186.1111085971099 0.0007295005262563 0.0020818197192241 285.3760407696706 0.0007100674012849 0.0029439986332687 414.6083354821351 0.0011457054613979 0.0032102987019359 280.2027929603142 +r_2482 PS decarboxylase (1-18:0, 2-16:1), vacuolar membrane 7.606605882136595e-05 0.0002160356568916 284.010582694914 0.0001243948230918 0.0003883076348869 312.1573914696586 0.000317632000656 0.0004024433685276 126.70114084742316 0.0004284563562452 0.000751225306332 175.33298208372926 0.0006562420205939 0.0011202756553629 170.71074698159288 0.0005856889536101 0.0012498518467433 213.3985691618823 0.0007899396909825 0.0018362206182757 232.4507350671229 0.001119375967723 0.0031976118664402 285.66022128780315 0.0011659957459364 0.0018992815131538 162.88923178089988 +r_2483 PS decarboxylase (1-18:1, 2-16:1), vacuolar membrane 9.800383158245757e-06 0.0002002271053581 2043.053849273888 1.5462483064199148e-05 0.0002977370702848 1925.5450049561964 2.0947498570313098e-05 0.0003344183295744 1596.4594934900174 4.203415965639207e-05 0.0006449829665735 1534.425742886253 4.350367932250252e-05 0.0008574213655388 1970.9168945978145 5.075117935477155e-05 0.0006524119630832 1285.5109405885253 6.776831318296791e-05 0.0012350375936047 1822.4411020388025 7.83892324194028e-05 0.0015828397813107 2019.2056133961144 0.0001820244524426 0.0027054271593791 1486.2987489172017 +r_2484 PS decarboxylase (1-16:0, 2-18:1), vacuolar membrane 0.0001925997084327 0.0003073822276101 159.59641378035667 0.0003125198262818 0.0004202714473417 134.47833129241775 0.0008866477325929 0.0009032916185523 101.87717008091911 0.0012341472728362 0.001415611149224 114.70358363072424 0.0017716340908523 0.0022345360906488 126.12853309758503 0.001153214600039 0.001977924659378 171.5140147645644 0.0024679092594987 0.0027191208835095 110.17912725290957 0.0030374172600583 0.0031991373332413 105.32426266583808 0.0037180740898817 0.0038716035997763 104.12927516190004 +r_2485 PS decarboxylase (1-16:1, 2-18:1), vacuolar membrane 2.442327536171555e-05 0.000226687414607 928.1614003435404 2.85983633962679e-05 0.000234352647024 819.4617425366905 8.012232498475257e-05 0.0004825983557118 602.3269492038671 0.0001036770893608 0.0005949678146736 573.866240209548 0.0001972253621641 0.001229361537062 623.3283202385645 0.0001537587610342 0.0009418992075569 612.5824643887075 0.0001841435834228 0.0013272601232462 720.7745708949186 0.0002858847270083 0.0018286923850324 639.6607486412238 0.0002918397415695 0.0024972627333964 855.6965956610541 +r_2486 PS decarboxylase (1-18:0, 2-18:1), vacuolar membrane 1.974162761996894e-05 0.0001126588022278 570.6662307512227 3.466133054515255e-05 0.000291212934614 840.166635365421 0.0001067184339842 0.00055951350583 524.2894642857791 0.0001320265399501 0.0006589558322649 499.1086129454532 0.000183443021804 0.001152800207413 628.4241265086712 0.0001985522835905 0.0008826881581387 444.5620781470887 0.0003138695593335 0.0021545186399635 686.4375903602389 0.0003607321607927 0.0028292350486496 784.303523820059 0.0002863339627178 0.0022335713526464 780.0581291319343 +r_2487 PS decarboxylase (1-18:1, 2-18:1), vacuolar membrane 1.5476370737659267e-05 0.000258964557688 1673.289959757156 1.7980243067933403e-05 0.0003175113060406 1765.8899539960037 3.247680560698852e-05 0.0004642467000488 1429.4715609250677 3.820901052352666e-05 0.0005954513192547 1558.4054941389804 7.74237777956319e-05 0.0012823655972132 1656.2942725401192 6.046070021522032e-05 0.0009423685022396 1558.6463585191088 8.366810115575754e-05 0.0015090541322795 1803.6194337317588 0.0001826344240173 0.0029966294129323 1640.7801700341854 0.0001503481432771 0.0024995958026233 1662.5385243474957 +r_2488 PE methyltransferase (1-16:0, 2-16:1), ER membrane 0.0003002037958613 0.0003291477259733 109.6414270941984 0.0004905836980251 0.0004683538388729 95.46869183755324 0.0010654764937211 0.0007360317594761 69.08005608884986 0.0016886583019257 0.0011330391608699 67.09700592345064 0.0023487201849303 0.0017916892277821 76.2836390336248 0.0028286580615481 0.0019264320365507 68.10409723034265 0.0032232383139884 0.0028683462347291 88.98957989798197 0.0037977011761517 0.0033196126910899 87.4111083814607 0.0041070365500357 0.0038497385701594 93.73519137846505 +r_2489 PE methyltransferase (1-16:1, 2-16:1), ER membrane 4.926642318549115e-05 0.0003461820670124 702.6734327942595 6.501595098909749e-05 0.0004062714838037 624.8797066305268 0.0001843387258269 0.0008535251638267 463.0199975603634 0.0002060683130623 0.0009972262325044 483.9299248315926 0.0003096558973246 0.0018303565289019 591.0937090867632 0.0004186048774477 0.0017976887141061 429.44762733458975 0.0004421280164742 0.0027866921235813 630.2907799881121 0.0006587366594969 0.0044736332226611 679.1231606993667 0.0006991435470908 0.0040563604044073 580.1899225539487 +r_2490 PE methyltransferase (1-18:0, 2-16:1), ER membrane 3.918065126439695e-05 0.000327467651095 835.7891983091333 6.089748061895209e-05 0.0004835026610881 793.9616814586097 0.0001057818332017 0.0005785121553809 546.891784601287 0.0001606279593768 0.0009604256821816 597.9193696463539 0.0002353781400893 0.0015057039286382 639.6957372791695 0.0002813401353822 0.0016389646892475 582.5563021858761 0.0003654693647529 0.002834097857098 775.467968160222 0.0004854192642202 0.0038873121972108 800.8153948021528 0.0004295236731973 0.002683200505506 624.6921119696899 +r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 2.856603177749897e-05 0.0003513440304776 1229.9364266421508 2.7765278062037645e-05 0.0004016408041645 1446.557831213243 4.470742175650413e-05 0.0005556008991183 1242.7486920279898 7.210862556518126e-05 0.0008615779548617 1194.8334170965263 0.0001499887869989 0.0017900113579898 1193.4301182144766 9.029390399703664e-05 0.0010957944294844 1213.5862787817512 0.0001359497414191 0.0019505932251106 1434.7899486591507 0.0002178764799522 0.003192529877647 1465.2934903057671 0.0003599694292482 0.0041371433678578 1149.3040885439182 +r_2492 PE methyltransferase (1-16:0, 2-18:1), ER membrane 0.0003951871238258 0.0003404159596279 86.14044818372403 0.0006402598691627 0.0004392090960994 68.59856712147426 0.0014765662874454 0.0007526091072628 50.9702214971256 0.0021594035632876 0.0012751829218502 59.052552451511566 0.003047806227289 0.0019645075727335 64.45644592310435 0.0035628062774472 0.0019245620366656 54.01814992996306 0.004019274775406 0.0027235300002303 67.76172698855191 0.0046454791832034 0.00362256107368 77.98035317385703 0.0056703568591325 0.004379284240929 77.23119284593054 +r_2493 PE methyltransferase (1-16:1, 2-18:1), ER membrane 4.864916230131779e-05 0.0003379288235718 694.6241365448785 6.35694733032754e-05 0.0004171162015517 656.1580266078798 0.0001421465022311 0.0007502573271718 527.805690182645 0.0001716713673621 0.0008089029552329 471.1927024653794 0.0003433586080432 0.0018768276230771 546.6085833038918 0.0002739955172208 0.00158666541769 579.0844440754446 0.000426688017837 0.0025247861437911 591.7171418569139 0.0005290613193443 0.0036038749056153 681.1828371958326 0.0004806287555544 0.003541398554167 736.8261913671626 +r_2494 PE methyltransferase (1-18:0, 2-18:1), ER membrane 3.292421511817927e-05 0.0002246351456629 682.2794252092992 5.980471273289056e-05 0.0003984503731561 666.2524656472369 0.0001214535754972 0.0006312296510433 519.7291627347813 0.0001974612927925 0.0009729663114899 492.7377400046569 0.0002720786780812 0.0016372796151327 601.7669692748245 0.0003112545517942 0.0014498962116798 465.82329585918575 0.0004981951001876 0.0029662585952044 595.4009973376249 0.0005287253624989 0.0037381364594446 707.0091061598766 0.0004426420981899 0.0031716821651612 716.5342334429753 +r_2495 PE methyltransferase (1-18:1, 2-18:1), ER membrane 2.477347812345468e-05 0.0003318240154369 1339.4324922133987 3.830250716395519e-05 0.0004758341932103 1242.3056046267054 5.9169213210862494e-05 0.000664312044669 1122.732597950307 8.425589619196711e-05 0.0009364413753494 1111.4253336239435 0.0001668278554483 0.0019092551965055 1144.4462864874772 0.0001231928298951 0.0014736792087896 1196.2378086803749 0.0001831359609784 0.0023877800347394 1303.829145287874 0.0003293696756599 0.0040429948797714 1227.4945687306276 0.0003092725046401 0.0038695483419816 1251.1776132456885 +r_2496 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 0.0003002037958613 0.0003291477259733 109.6414270941984 0.0004905836980251 0.0004683538388729 95.46869183755324 0.0010654764937211 0.0007360317594761 69.08005608884986 0.0016886583019257 0.0011330391608699 67.09700592345038 0.0023487201849303 0.0017916892277821 76.28363903362494 0.0028286580615481 0.0019264320365507 68.10409723034265 0.0032232383139884 0.0028683462347291 88.98957989798224 0.0037977011761517 0.0033196126910899 87.4111083814607 0.0041070365500357 0.0038497385701594 93.73519137846505 +r_2497 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 4.926642318549115e-05 0.0003461820670124 702.6734327942595 6.501595098909749e-05 0.0004062714838037 624.8797066305268 0.0001843387258269 0.0008535251638267 463.0199975603634 0.0002060683130623 0.0009972262325044 483.9299248315926 0.0003096558973246 0.0018303565289019 591.0937090867632 0.0004186048774477 0.0017976887141061 429.44762733458975 0.0004421280164742 0.0027866921235813 630.2907799881121 0.0006587366594969 0.0044736332226611 679.1231606993667 0.0006991435470908 0.0040563604044073 580.1899225539487 +r_2498 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 3.918065126439695e-05 0.000327467651095 835.7891983091333 6.089748061895209e-05 0.0004835026610881 793.9616814586096 0.0001057818332017 0.0005785121553809 546.891784601287 0.0001606279593768 0.0009604256821816 597.9193696463539 0.0002353781400893 0.0015057039286382 639.6957372791695 0.0002813401353822 0.0016389646892475 582.5563021858761 0.0003654693647529 0.002834097857098 775.467968160222 0.0004854192642202 0.0038873121972108 800.8153948021528 0.0004295236731973 0.002683200505506 624.6921119696899 +r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 2.856603177749897e-05 0.0003513440304776 1229.9364266421508 2.776527806203764e-05 0.0004016408041645 1446.5578312132432 4.470742175650413e-05 0.0005556008991183 1242.7486920279898 7.210862556518125e-05 0.0008615779548617 1194.8334170965263 0.0001499887869989 0.0017900113579898 1193.4301182144766 9.029390399703664e-05 0.0010957944294844 1213.5862787817512 0.0001359497414191 0.0019505932251106 1434.7899486591507 0.0002178764799522 0.003192529877647 1465.2934903057671 0.0003599694292482 0.0041371433678578 1149.3040885439182 +r_2500 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 0.0003951871238258 0.0003404159596279 86.14044818372403 0.0006402598691627 0.0004392090960994 68.59856712147415 0.0014765662874454 0.0007526091072628 50.9702214971256 0.0021594035632876 0.0012751829218502 59.052552451511566 0.003047806227289 0.0019645075727335 64.45644592310433 0.0035628062774472 0.0019245620366656 54.01814992996306 0.004019274775406 0.0027235300002303 67.76172698855184 0.0046454791832034 0.00362256107368 77.98035317385715 0.0056703568591325 0.004379284240929 77.23119284593054 +r_2501 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 4.8649162301317786e-05 0.0003379288235718 694.6241365448786 6.356947330329602e-05 0.0004171162015517 656.1580266076649 0.0001421465022311 0.0007502573271718 527.805690182645 0.0001716713673621 0.0008089029552329 471.1927024653794 0.0003433586080432 0.0018768276230771 546.6085833038918 0.0002739955172208 0.00158666541769 579.0844440754446 0.000426688017837 0.0025247861437911 591.7171418569139 0.0005290613193443 0.0036038749056153 681.1828371958326 0.0004806287555544 0.003541398554167 736.8261913671626 +r_2502 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 3.292421511817928e-05 0.0002246351456629 682.2794252092991 5.980471273289056e-05 0.0003984503731561 666.2524656472369 0.0001214535754972 0.0006312296510433 519.7291627347813 0.0001974612927925 0.0009729663114899 492.7377400046569 0.0002720786780813 0.0016372796151327 601.7669692747597 0.0003112545517942 0.0014498962116798 465.82329585918575 0.0004981951001876 0.0029662585952044 595.4009973376275 0.0005287253624989 0.0037381364594446 707.0091061598766 0.0004426420981899 0.0031716821651612 716.5342334429753 +r_2503 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-18:1), ER membrane 2.477347812345468e-05 0.0003318240154369 1339.4324922133987 3.830250716395519e-05 0.0004758341932103 1242.3056046267054 5.9169213210862494e-05 0.000664312044669 1122.732597950307 8.425589619196711e-05 0.0009364413753494 1111.4253336239435 0.0001668278554483 0.0019092551965055 1144.4462864874772 0.0001231928298951 0.0014736792087896 1196.2378086803749 0.0001831359609784 0.0023877800347394 1303.8291452878734 0.0003293696756599 0.0040429948797714 1227.4945687306276 0.0003092725046401 0.0038695483419816 1251.1776132456882 +r_2504 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 0.0003002037958613 0.0003291477259733 109.6414270941984 0.0004905836980251 0.0004683538388729 95.46869183755324 0.0010654764937211 0.0007360317594761 69.08005608884986 0.0016886583019257 0.0011330391608699 67.09700592345038 0.0023487201849303 0.0017916892277821 76.28363903362494 0.0028286580615481 0.0019264320365507 68.10409723034265 0.0032232383139884 0.0028683462347291 88.98957989798224 0.0037977011761517 0.0033196126910899 87.4111083814607 0.0041070365500357 0.0038497385701594 93.73519137846505 +r_2505 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 4.926642318547423e-05 0.0003461820670124 702.6734327945023 6.501595098912023e-05 0.0004062714838037 624.8797066303617 0.0001843387258269 0.0008535251638267 463.0199975603634 0.0002060683130623 0.0009972262325044 483.9299248315926 0.0003096558973246 0.0018303565289019 591.0937090867632 0.0004186048774477 0.0017976887141061 429.44762733458975 0.0004421280164742 0.0027866921235813 630.2907799881121 0.0006587366594969 0.0044736332226611 679.1231606993667 0.0006991435470908 0.0040563604044073 580.189922553966 +r_2506 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 3.918065126439431e-05 0.000327467651095 835.7891983091899 6.089748061895209e-05 0.0004835026610881 793.9616814586096 0.0001057818332017 0.0005785121553809 546.891784601287 0.0001606279593768 0.0009604256821816 597.9193696463539 0.0002353781400893 0.0015057039286382 639.6957372791692 0.0002813401353822 0.0016389646892475 582.5563021858761 0.000365469364753 0.002834097857098 775.4679681601729 0.0004854192642202 0.0038873121972108 800.8153948021528 0.0004295236731973 0.002683200505506 624.6921119696899 +r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 2.856603177749897e-05 0.0003513440304776 1229.9364266421508 2.7765278062037645e-05 0.0004016408041645 1446.557831213243 4.470742175650413e-05 0.0005556008991183 1242.7486920279898 7.210862556518125e-05 0.0008615779548617 1194.8334170965263 0.0001499887869989 0.0017900113579898 1193.4301182144764 9.029390399703668e-05 0.0010957944294844 1213.586278781751 0.0001359497414191 0.0019505932251106 1434.7899486591507 0.0002178764799522 0.003192529877647 1465.2934903057671 0.0003599694292482 0.0041371433678578 1149.3040885439182 +r_2508 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 0.0003951871238258 0.0003404159596279 86.14044818372403 0.0006402598691627 0.0004392090960994 68.59856712147415 0.0014765662874454 0.0007526091072628 50.9702214971256 0.0021594035632876 0.0012751829218502 59.052552451511566 0.003047806227289 0.0019645075727335 64.45644592310433 0.0035628062774472 0.0019245620366656 54.01814992996306 0.004019274775406 0.0027235300002303 67.76172698855184 0.0046454791832034 0.00362256107368 77.98035317385715 0.0056703568591325 0.004379284240929 77.23119284593054 +r_2509 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 4.8649162301317786e-05 0.0003379288235718 694.6241365448786 6.356947330329602e-05 0.0004171162015517 656.1580266076649 0.0001421465022311 0.0007502573271718 527.805690182645 0.0001716713673621 0.0008089029552329 471.1927024653794 0.0003433586080432 0.0018768276230771 546.6085833038917 0.0002739955172208 0.00158666541769 579.0844440754446 0.000426688017837 0.0025247861437911 591.7171418569139 0.0005290613193443 0.0036038749056153 681.1828371958326 0.0004806287555544 0.003541398554167 736.8261913671626 +r_2510 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 3.292421511817928e-05 0.0002246351456629 682.2794252092991 5.980471273289056e-05 0.0003984503731561 666.252465647237 0.0001214535754972 0.0006312296510433 519.7291627347813 0.0001974612927925 0.0009729663114899 492.7377400046569 0.0002720786780813 0.0016372796151327 601.7669692747597 0.0003112545517942 0.0014498962116798 465.82329585918575 0.0004981951001876 0.0029662585952044 595.4009973376275 0.0005287253624989 0.0037381364594446 707.0091061598766 0.0004426420981899 0.0031716821651612 716.5342334429753 +r_2511 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-18:1), ER membrane 2.477347812345468e-05 0.0003318240154369 1339.4324922133987 3.830250716395519e-05 0.0004758341932103 1242.3056046267054 5.9169213210862494e-05 0.000664312044669 1122.732597950307 8.425589619196711e-05 0.0009364413753494 1111.4253336239435 0.0001668278554483 0.0019092551965055 1144.4462864874772 0.0001231928298951 0.0014736792087896 1196.2378086803749 0.0001831359609784 0.0023877800347394 1303.8291452878734 0.0003293696756599 0.0040429948797714 1227.4945687306276 0.0003092725046401 0.0038695483419816 1251.1776132456882 +r_2512 DAG kinase (1-16:0, 2-16:1), ER membrane 0.0003656558856152 0.0040369271010979 1104.0235532666377 0.0007927897004491 0.0085904032206561 1083.56645095025 0.0006388060827955 0.0064964712441626 1016.9707864603084 0.0007372592874213 0.0083891102601111 1137.877867833069 0.0015533561398532 0.0185088890623868 1191.5418871125903 0.0017600764440744 0.0176550055399598 1003.0817467842616 0.0029340941726 0.0293555990001374 1000.4995502282704 0.0042735159013731 0.0456789060172343 1068.8834924554153 0.0026434221251182 0.0345963299009969 1308.770535445556 +r_2513 DAG kinase (1-16:1, 2-16:1), ER membrane 0.000457205043517 0.0045560298132813 996.4959656248724 0.0009869674523219 0.0092243426121835 934.6146714850464 0.0005713427559038 0.0061081584895558 1069.0882883240542 0.0010368641365579 0.0102021616859516 983.9439253651374 0.0019581121902605 0.0189059791405355 965.5207313744364 0.0015680961877058 0.016505738767369 1052.597340442321 0.0027858184451713 0.0279106149223655 1001.8820490883936 0.0034031108799397 0.0403864370260995 1186.750548275258 0.0039162479216195 0.0396790944168286 1013.1915856956106 +r_2514 DAG kinase (1-18:0, 2-16:1), ER membrane 0.0004177135788577 0.0045774010889513 1095.8229084790662 0.0008013376318566 0.0084869702024768 1059.1004172377022 0.0004387232583079 0.0053690149350189 1223.7816968549514 0.000948438560364 0.0100763620973984 1062.4159032010652 0.0017641669274316 0.0190791477418593 1081.481998397725 0.000856280026526 0.0112445567589193 1313.1868560030414 0.0017596314992583 0.0216780170057896 1231.9634545600247 0.0035006305250319 0.0401278253372721 1146.3027888927363 0.0037097049427628 0.0397072259911659 1070.3607592466178 +r_2515 DAG kinase (1-18:1, 2-16:1), ER membrane 0.0004657019400526 0.0049362981488694 1059.969419133456 0.0006190671943645 0.0071628502884851 1157.0392283243732 0.0005213603957568 0.0063138145051373 1211.0268744084988 0.0009355240395296 0.0103330459782194 1104.5195571259098 0.0024269219666016 0.0227584817265077 937.7508646631773 0.0011691159637076 0.0121605612932628 1040.1501365782142 0.0026942025795791 0.0301776289030052 1120.0950192735284 0.003994757367475 0.0432859678109313 1083.5693842975732 0.0042025861951528 0.0463300653878883 1102.417969233414 +r_2516 DAG kinase (1-16:0, 2-18:1), ER membrane 0.0003576374433404 0.0038227983795799 1068.9032848110526 0.0005534518580677 0.0066354209104745 1198.915644377964 0.0006485714654968 0.0071818100134288 1107.32747206624 0.0009272735295666 0.0098253921339925 1059.600195703226 0.0014872665616032 0.015982846545441 1074.645726466941 0.0011436782671795 0.0134777874492193 1178.459697626041 0.0021566563000162 0.0238461007396588 1105.6977757410327 0.003721957549197 0.0388204528115285 1043.0117028041686 0.0046209197266778 0.0462005573046472 999.8130250546936 +r_2517 DAG kinase (1-16:1, 2-18:1), ER membrane 0.0002930033853752 0.0035152703883987 1199.73712382098 0.000652369570893 0.0073642775421659 1128.8505581407146 0.0006321838604802 0.0068642681149193 1085.8024926015044 0.000680229849774 0.0088849916195839 1306.1749087510534 0.0024491635687816 0.0236929396119836 967.3890267676056 0.001649888404618 0.016971999604634 1028.675609643029 0.0028082571683409 0.0304827130769695 1085.4672934024177 0.0046765517983563 0.048546014421918 1038.0728475835565 0.0034223815815564 0.0376736868175891 1100.8032248834097 +r_2518 DAG kinase (1-18:0, 2-18:1), ER membrane 0.0003244903402924 0.0043567925832076 1342.6570970589537 0.000705351874813 0.0080067820416697 1135.1471978141526 0.0005285421515813 0.0064179006125664 1214.264669972756 0.0007172158880333 0.0090870114865065 1266.9841310158315 0.0012373430952851 0.016602040448205 1341.7491487580896 0.0013480843158573 0.0153442563562028 1138.2267544922995 0.0023643806901609 0.0291038384272454 1230.9286126535274 0.0033430444921496 0.0417102307794845 1247.6720210404408 0.0041453826759689 0.0481675917089876 1161.9576640829337 +r_2519 DAG kinase (1-18:1, 2-18:1), ER membrane 0.000332903958067 0.0040086844112238 1204.1564283284715 0.0006661482069486 0.0078752143008374 1182.2015309340782 0.0006706695668056 0.0075355549870319 1123.586839182672 0.0008394695083319 0.00986587421615 1175.251050601473 0.0008947408279805 0.0149229848307338 1667.8555805277192 0.0010359144257496 0.0142399895447032 1374.6299106124293 0.0025257357030428 0.0291086581272384 1152.482347704495 0.003113547756306 0.0400919495541295 1287.661301257689 0.0023261700546333 0.0342424371874207 1472.0521880683114 +r_2520 ethanolaminephosphotransferase (1-16:0, 2-16:1), ER membrane -1.1869331466456724e-10 1.426670492512132e-09 -1201.980496158497 -1.3899911954640754e-10 1.5924573245426203e-09 -1145.6600083074252 -1.2688386281987343e-10 1.2959236653551751e-09 -1021.3463213954096 -1.373288591976489e-10 1.377578986568592e-09 -1003.1241755135592 -1.2583443663664198e-10 1.602252330677935e-09 -1273.3019461950469 -8.84835974951671e-11 1.368583270452665e-09 -1546.7084399765915 -1.4539999999999942e-10 1.390052261268603e-09 -956.0194369110104 -6.442357496682184e-11 1.3429551888047695e-09 -2084.571043280961 -5.5386767119537095e-11 1.3045601041269494e-09 -2355.364235849721 +r_2521 ethanolaminephosphotransferase (1-16:1, 2-16:1), ER membrane -2.713999999999981e-10 1.5696607298908894e-09 -578.3569380585483 -2.5176977099271813e-10 1.6629856740912804e-09 -660.5184043875462 -1.5720000000000063e-10 1.290434502111905e-09 -820.8870878574428 -2.2539999999999914e-10 1.4494878554194703e-09 -643.0735827060673 -2.2777285083802987e-10 1.592403791180987e-09 -699.1192257207824 -1.1659790004078935e-10 1.2809808064577843e-09 -1098.6311125754924 -3.065581890543305e-10 1.615423344443531e-09 -526.9548823428213 -1.7978605742092396e-10 1.403673712324546e-09 -780.7467010849437 -2.094000000000001e-10 1.4540888951171964e-09 -694.4073042584506 +r_2522 ethanolaminephosphotransferase (1-18:0, 2-16:1), ER membrane -2.622629047951804e-11 1.3899631850428648e-09 -5299.884808827178 2.7664642747478667e-11 1.252653655013194e-09 4527.995052917719 -1.8483074015216525e-11 1.233585277490206e-09 -6674.134813692975 2.034991218773692e-11 1.370736706882707e-09 6735.835979227115 4.458448012961338e-11 1.2723624365552035e-09 2853.82364638158 -6.37109205606071e-11 1.3829867787388063e-09 -2170.7217013497625 1.9040932820692888e-11 1.4365124723063726e-09 7544.338745553634 5.738911565597199e-11 1.2504094420356123e-09 2178.8268171466293 -4.1322208555021086e-11 1.380886701826422e-09 -3341.754349813497 +r_2523 ethanolaminephosphotransferase (1-18:1, 2-16:1), ER membrane -1.0126367274084128e-10 1.4592801848266644e-09 -1441.0697788547743 -1.4912005241173735e-10 2.0117000452742936e-09 -1349.047302987637 -1.8432585326681062e-10 1.4261726816540823e-09 -773.7236293108084 -1.9549597565807318e-10 1.5670463837502523e-09 -801.5747528691084 -2.55427149161968e-10 1.6955018620406302e-09 -663.7907785462153 -1.8964788825563927e-10 1.8126332605952907e-09 -955.788792202062 -1.2943457317447435e-10 1.4336320738631112e-09 -1107.6113890611075 -1.365992839190161e-10 1.416729841847094e-09 -1037.1429492170787 -1.124246034617019e-10 1.5853860542835447e-09 -1410.177136914355 +r_2524 ethanolaminephosphotransferase (1-16:0, 2-18:1), ER membrane 4.1801414735374796e-10 1.2493343646950834e-09 298.8737038217571 3.9376100217709507e-10 1.5542692656896887e-09 394.7240222104707 4.069974237632839e-10 1.099717116674232e-09 270.20247610064604 3.8041484472668764e-10 1.00014062766984e-09 262.9078863597975 4.0387723644747006e-10 9.798494916204376e-10 242.61072504092 3.4151755213158583e-10 1.4705218652565608e-09 430.5845647107392 3.7967703356168357e-10 1.244004728078719e-09 327.64813726259115 3.6855000000001534e-10 9.583668874278859e-10 260.03714215923094 3.7362664988656546e-10 9.89722264853793e-10 264.8960573755316 +r_2525 ethanolaminephosphotransferase (1-16:1, 2-18:1), ER membrane 3.4534276171717707e-10 1.0475115133443038e-09 303.3251683445378 2.7779870257017896e-10 1.929237385831557e-09 694.4731447563848 8.773097358860398e-11 1.2927497101690923e-09 1473.538543218694 2.965859415591633e-10 1.2203307079398863e-09 411.4593906658429 3.024430448972413e-10 1.0486399683638391e-09 346.72312227253485 2.7171721983254446e-10 1.1473473832928434e-09 422.2578841340778 3.0138642200823024e-10 1.4379498440565635e-09 477.1116875388952 2.4797953585789207e-10 1.1456103536852115e-09 461.9777796268312 2.2928584671051277e-10 1.168676763878955e-09 509.7029671240372 +r_2526 ethanolaminephosphotransferase (1-18:0, 2-18:1), ER membrane 5.155681709256191e-10 1.186822645343174e-09 230.19703547882463 4.296918024408289e-10 1.1825121494021376e-09 275.2000719317833 5.625981361298152e-10 1.4151433552428955e-09 251.53715669551423 5.32369925290916e-10 1.3050979514428343e-09 245.14870007535788 5.716630084957103e-10 1.255269895462478e-09 219.58214486636624 4.421725935432931e-10 1.118196029911923e-09 252.886779108448 6.096116953304214e-10 1.6742833713471212e-09 274.6475148314908 5.40782252852563e-10 1.0357872421520484e-09 191.53499152170627 5.987256800056504e-10 1.066370309539925e-09 178.10665971933275 +r_2527 ethanolaminephosphotransferase (1-18:1, 2-18:1), ER membrane 5.646522210257721e-10 1.0749705014465499e-09 190.37745029917903 5.387727930153672e-10 1.4686545701794707e-09 272.5925639191623 5.947662566202551e-10 1.2565884331142644e-09 211.27433157603767 5.715042110912913e-10 1.4379857571996899e-09 251.61420148660773 5.798666666666997e-10 1.0291365452893687e-09 177.47813496596518 4.764329408448672e-10 1.073990146199585e-09 225.4231506946305 5.72676676392793e-10 1.738035260402378e-09 303.49328548702374 5.843080119407067e-10 1.0607078267987478e-09 181.53230917983444 5.912954025336147e-10 1.1827435360962092e-09 200.02582990301048 +r_2528 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 4.913135123430036e-05 0.0009710291761361 1976.394199918262 0.0001035323470784 0.0017677428545859 1707.4304837759112 0.0001146369262593 0.0016025140200483 1397.903862515324 0.0001645128839138 0.0021179862045984 1287.4287740939544 0.0002790021782856 0.004397540595444 1576.1671190044565 0.0002194611174508 0.0034370076864905 1566.1123603187143 0.0005754402788433 0.0088877170045871 1544.507281007768 0.0008535531523714 0.0134201067165193 1572.2637400183128 0.0008328789683728 0.0128391309558671 1541.5362187558185 +r_2529 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 6.143687940468255e-05 0.0011195661423711 1822.3030746672755 0.000143481075745 0.0024369518665935 1698.4482824223146 0.0001506700200027 0.0021179597813837 1405.6942325655484 0.0001780679875979 0.0029040050575189 1630.8406113267367 0.0002457799310909 0.0044878606071579 1825.9670703128425 0.0002391420049853 0.0040498543754683 1693.4935272943562 0.0005371043347335 0.008935157824487 1663.5795406343864 0.0005391162504695 0.0115665565639087 2145.466131624571 0.0004798053424197 0.0100861479739866 2102.1333199666883 +r_2530 cholinephosphotransferase (1-18:0, 2-16:1), ER membrane 4.923520745171633e-05 0.0011226608498713 2280.199288227412 0.0001103757745614 0.002284804497577 2070.023523418535 5.707661622814131e-05 0.0013335729012362 2336.461040202128 8.900038661332635e-05 0.0019987305091222 2245.754861499658 0.0003468709870088 0.0062573746180583 1803.9486876714104 0.0001945670466189 0.0041567642740254 2136.417418190004 0.0001310622845926 0.004251558012704 3243.9217933058144 0.0006765290270605 0.0129376701616662 1912.359949709548 0.0006703963051426 0.0128019414861078 1909.608001700452 +r_2531 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 6.436803364653863e-05 0.0012670795153758 1968.491879577574 9.3121420331139e-05 0.0020067530167458 2154.985404657504 7.145614537716228e-05 0.0015621740213746 2186.19967971835 8.012731771767227e-05 0.0020385234641717 2544.1054589577543 0.000306040260528 0.0057844215138734 1890.085148892728 0.0002715084203827 0.0048197496822848 1775.1750297431122 0.0004200142846052 0.0082733518890807 1969.778693802552 0.0008505926119055 0.0145443306680549 1709.905595755479 0.0005709211563833 0.0122441659208923 2144.633419867654 +r_2532 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 6.583873382042533e-05 0.0011530679600711 1751.3519673936742 9.09326960329052e-05 0.0018426525982671 2026.3916925990536 0.0001170956659918 0.0018696720302981 1596.7047238356238 0.0001323982787462 0.0022852756936126 1726.0614830143672 0.0003115407241859 0.0055111168535744 1768.9876236806974 0.0003480934829597 0.0050830036682048 1460.2409746330109 0.0003663302725801 0.0067854071434245 1852.264923570955 0.000584211516864 0.0108611518446803 1859.1129293343447 0.0008803288333641 0.0134012097386987 1522.2959002133068 +r_2533 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 5.401114944328856e-05 0.001102432604713 2041.120428052772 0.0001038270646158 0.0021780334514136 2097.7511590762406 9.66417439652703e-05 0.0017036054028856 1762.8049049879578 8.452509625710992e-05 0.0019005954247326 2248.55753958726 0.0002152454250472 0.0047733936710388 2217.6516272019344 0.0002256811522473 0.0044279570985538 1962.0411604868368 0.000372086713683 0.0080785125983694 2171.1370767327835 0.0005781842318331 0.0122903678906537 2125.683685922659 0.0004360342414154 0.0099325426524096 2277.9272151118275 +r_2534 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 6.489738700060875e-05 0.0011264066693302 1735.6733782203796 9.678638823173176e-05 0.0019921540289799 2058.2997933657784 0.0001083753726214 0.0019554082530092 1804.2920690467265 0.0001372401436365 0.0027758863772324 2022.6489886104844 0.0001136980650495 0.0033049039713179 2906.7372165721777 0.0002342367978925 0.004461051272691 1904.5048911307745 0.0006117143713163 0.0096296762626818 1574.2112191937133 0.0005724273999136 0.0112161337685677 1959.3984792235844 0.0007091553612538 0.0125996708746975 1776.7151689327093 +r_2535 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 4.984050717714904e-05 0.0011226703932839 2252.526021241408 0.0001554923657171 0.0026519719196159 1705.5319130200387 9.855459319510056e-05 0.0018791995958042 1906.760035104784 0.0001303831450482 0.0026500340833352 2032.4974384946595 0.0004940726476976 0.007349204746639 1487.4745203738528 0.0002829600100753 0.0049720900645604 1757.1705850719525 0.0004088161966244 0.0074941053960719 1833.1234080132035 0.0007671881037325 0.0139848194196795 1822.867084570257 0.0005911697815649 0.0123108885386597 2082.462419860165 +r_2536 phosphatidylglycerolphosphate synthase (1-16:0, 2-16:1), mitochondrial membrane 5.236520833172447e-05 0.0010249704442945 1957.350074502711 8.050898083191547e-05 0.0017133985018212 2128.207914342436 9.34004089337988e-05 0.0017015816815373 1821.8139523815696 0.0001187703613856 0.0023266367247574 1958.9371435888424 6.252758041670461e-05 0.0023078766852061 3690.9739187501614 0.0001652168879002 0.0035112956470439 2125.26436714126 0.0005185826570425 0.0083994346599793 1619.6906213332743 0.0003373436973208 0.0081260894771017 2408.845797813341 0.0005200875789425 0.0101876811508508 1958.839542287344 +r_2537 phosphatidylglycerolphosphate synthase (1-16:1, 2-16:1), mitochondrial membrane 5.254870338206187e-05 0.0010218497799215 1944.5765816370888 0.0001179104240206 0.002063788855383 1750.3022930544234 6.354190701671517e-05 0.0013870687848356 2182.919666655237 9.536257596622908e-05 0.0020579160778064 2157.9912842698177 0.0002225682191635 0.0044819042268166 2013.721565307437 0.0001839340732482 0.0036766542301841 1998.8978470682864 0.0003099892850178 0.0064592362251056 2083.696610588798 0.0004614117026596 0.0097223967422344 2107.097996473236 0.0002449098477489 0.0069562843442114 2840.3448894154376 +r_2538 phosphatidylglycerolphosphate synthase (1-18:0, 2-16:1), mitochondrial membrane 4.670009335953755e-05 0.0009564670463431 2048.1052125087813 9.522047013172668e-05 0.0018651635707813 1958.7842490181968 5.474089503821531e-05 0.0012885104009134 2353.835098994839 0.0001190410751422 0.002329734236941 1957.084337618717 0.0001616904313901 0.0038026361065242 2351.8003346459286 0.0001489887707782 0.003328390535316 2233.987513240252 0.0002155804100048 0.0053850642385709 2497.937655118929 0.0002495775444932 0.0072011328844675 2885.3288460260774 0.0003609329365318 0.0085000816834903 2355.030761439252 +r_2539 phosphatidylglycerolphosphate synthase (1-18:1, 2-16:1), mitochondrial membrane 5.237920201068043e-05 0.0010252504520399 1957.361725042936 0.0001221965280188 0.002098035475245 1716.9354230113663 9.202472220911724e-05 0.0016784100015821 1823.8685880171256 0.0001555949058997 0.0026642115865261 1712.2743004473502 0.0003639096722108 0.0057443052355619 1578.497543267841 0.0001635815684767 0.0034804324447907 2127.64339968099 0.0002952242999659 0.0062996613389912 2133.8559663676 0.0004993980856219 0.0101828165753476 2039.0179435040843 0.0002247548487016 0.0065404470559531 2910.036020906842 +r_2540 phosphatidylglycerolphosphate synthase (1-16:0, 2-18:1), mitochondrial membrane 6.640633078893425e-05 0.0011415224946327 1718.9964888453246 9.763962223212596e-05 0.0018713130121827 1916.550852413145 6.196220217305498e-05 0.0013842670997892 2234.0508426783567 0.0001093408374688 0.0022295534314061 2039.0857460200068 0.0002375180644751 0.0046525418324786 1958.815992695203 7.847886066970712e-05 0.0023693204431343 3019.055606714335 0.0003581856091303 0.0069429671413746 1938.371326037365 0.0004589703253468 0.0097754878029099 2129.873602508467 0.0005210772980991 0.0101967048649477 1956.8507210244725 +r_2541 phosphatidylglycerolphosphate synthase (1-16:1, 2-18:1), mitochondrial membrane 3.5885750829634285e-05 0.0008445754774759 2353.5120708091727 0.0001023566473516 0.0019319144830101 1887.43431227612 9.276501874595596e-05 0.0016888246756684 1820.5404348522968 6.913531587483523e-05 0.0017357547785706 2510.662975364364 0.0002908259078197 0.0051338560979319 1765.2677976384866 0.0002385349831386 0.0042105063038382 1765.1525358825986 0.0005188478384711 0.0084035868877209 1619.663081276912 0.0006254103506313 0.011402375794335 1823.1830961582336 0.0004009591933147 0.0089576194090301 2234.047643346684 +r_2542 PGP phosphatase (1-16:0, 2-16:1), mitochondrial membrane 5.236505443526401e-05 0.0010249704521593 1957.3558420079912 8.05089369839539e-05 0.0017133985038818 2128.209075997851 9.340010310806642e-05 0.0017015816983258 1821.819935634386 0.0001187702712802 0.0023266367189998 1958.9386248932733 6.252749498001143e-05 0.0023078765783678 3690.9787911791377 0.0001652166484517 0.0035112956583128 2125.2674541084443 0.0005185820834192 0.0083994346954021 1619.6924197652197 0.0003373434397478 0.0081260894209765 2408.847620410648 0.0005200873850217 0.0101876811607526 1958.840274567668 +r_2543 PGP phosphatase (1-16:1, 2-16:1), mitochondrial membrane 5.254851043128741e-05 0.0010218497786847 1944.5837194966 0.00011791038574 0.0020637888575704 1750.3028631600705 6.354184686198992e-05 0.0013870687875919 2182.921737551275 9.536255727454136e-05 0.0020579160786727 2157.9917081587246 0.0002225681830152 0.004481904228612 2013.721893171817 0.0001839339272829 0.0036766542370922 1998.8994370986843 0.000309989234346 0.0064592362275378 2083.6969519810973 0.0004614116493387 0.0097223967365815 2107.0982387449776 0.0002449097384511 0.0069562843480602 2840.346158570099 +r_2544 PGP phosphatase (1-18:0, 2-16:1), mitochondrial membrane 4.670001331118277e-05 0.0009564670502522 2048.108731530588 9.522035934692624e-05 0.0018651635050838 1958.786458984396 5.474069240796804e-05 0.0012885104095235 2353.843827770097 0.0001190410662377 0.002329734237396 1957.084484394136 0.0001616903406673 0.0038026361103825 2351.801656603827 0.0001489887233228 0.0033283905374406 2233.988226228017 0.0002155801593506 0.0053850642486073 2497.940564116887 0.0002495772040184 0.0072011328962701 2885.3327869396257 0.0003609323511397 0.0085000817024688 2355.034586294976 +r_2545 PGP phosphatase (1-18:1, 2-16:1), mitochondrial membrane 5.2379055117329166e-05 0.0010252504595445 1957.367228652739 0.0001221964739621 0.0020980354783941 1716.9361851181309 9.20244248957668e-05 0.0016784100178861 1823.874498305511 0.0001555944497435 0.0026642115978616 1712.2793276063362 0.0003639095851389 0.0057443052410792 1578.4979224675722 0.0001635812942298 0.0034804324579215 2127.6469747401115 0.0002952242699644 0.0062996613403975 2133.8561836923764 0.0004993979203004 0.0101828164999739 2039.018603411132 0.0002247546776569 0.0065404470618319 2910.038238143445 +r_2546 PGP phosphatase (1-16:0, 2-18:1), mitochondrial membrane 6.64060950374295e-05 0.0011415225083496 1719.0026121943006 9.763948627468464e-05 0.0018713130192781 1916.5535283682616 6.196181290521933e-05 0.0013842671172154 2234.064905965463 0.0001093407148069 0.0022295534374223 2039.0880390337904 0.000237517962881 0.0046525418376662 1958.8168327279827 7.847820407239348e-05 0.0023693204648873 3019.0808937239512 0.0003581849025743 0.0069429670664706 1938.37512875902 0.0004589699241034 0.0097754876807425 2129.8754378816307 0.0005210766103725 0.0101967049001943 1956.853310476399 +r_2547 PGP phosphatase (1-16:1, 2-18:1), mitochondrial membrane 3.5885700677844365e-05 0.0008445754796071 2353.515365880993 0.0001023566028086 0.0019319143461614 1887.434999942108 9.276436062236314e-05 0.0016888246270234 1820.553298371268 6.913500692829299e-05 0.0017357547908776 2510.674212672049 0.0002908258470587 0.0051338561013747 1765.268167632093 0.000238534896336 0.004210506312312 1765.1531817721466 0.0005188476684287 0.0084035868982215 1619.663614114337 0.0006254099303971 0.0114023758173889 1823.184324903312 0.0004009585774587 0.0089576194366024 2234.0510816292635 +r_2548 CL synthase (1-16:0, 2-16:1, 3-16:0, 4-16:1), mitochondrial membrane -3.4391677359406303e-10 4.952639567448487e-09 -1440.069210841766 2.079614792239252e-11 3.7897189422413834e-09 18223.17746721139 -1.0229031533685174e-11 3.9514295586739554e-09 -38629.55692004196 -1.7952025888050832e-10 4.356711100286802e-09 -2426.8632005408936 -2.7504908464819156e-10 4.350676076078095e-09 -1581.781696035432 -3.033952900749247e-10 4.505784520059768e-09 -1485.120127918613 -1.8948608241235528e-10 4.2949865153099456e-09 -2266.650120489215 -1.1303832780040608e-11 3.83766788993589e-09 -33950.14739347642 1.3828089117701408e-10 3.5012527949383604e-09 2531.985992523282 +r_2549 CL synthase (1-16:0, 2-16:1, 3-16:1, 4-16:1), mitochondrial membrane 1.3422929553874314e-10 2.231762283921461e-09 1662.6491817334304 4.4671736953597877e-10 2.0459450018232074e-09 457.995399630062 2.1819295677780343e-10 2.470591623029249e-09 1132.2966879930834 3.7810870625267247e-10 1.9908615268796475e-09 526.5315222731865 3.250321327149672e-10 2.081834660410886e-09 640.5011846125764 1.0446404872367336e-10 2.4268284757441903e-09 2323.123127425013 2.156945174585764e-10 2.428900666995246e-09 1126.0836369944875 2.2168678708352278e-10 2.3004630626134624e-09 1037.7086938188784 3.3975411433537115e-10 2.276810183056244e-09 670.1346906453662 +r_2550 CL synthase (1-16:0, 2-16:1, 3-18:0, 4-16:1), mitochondrial membrane 1.1777562705974808e-10 3.014768647732902e-09 2559.755972433496 4.719337242241996e-10 2.52913473678772e-09 535.9088802024698 3.055494263462383e-10 2.7971295041739915e-09 915.4425644394368 2.332955192559299e-10 2.682556270228979e-09 1149.853318565523 2.0635302853740118e-10 3.1098678704764903e-09 1507.0618989790262 -1.7499700766213314e-10 3.901719734246206e-09 -2229.592257816922 2.1881262755318323e-10 2.6924707656774443e-09 1230.4914920977442 1.9617441333443679e-10 2.311285867108424e-09 1178.1790641413363 1.8591666237173428e-10 2.950344746056484e-09 1586.917874072721 +r_2551 CL synthase (1-16:0, 2-16:1, 3-18:1, 4-16:1), mitochondrial membrane 1.322379632101174e-10 2.2959367830583162e-09 1736.2160814668812 5.250252766453607e-10 2.2754691374889304e-09 433.4018262945352 4.2520653662779187e-10 2.584503771050276e-09 607.8231514377313 3.7466289731666944e-10 1.544250989560582e-09 412.1707808860944 3.9374674948953956e-10 1.810123723357406e-09 459.7177565793452 2.0809753071349712e-10 2.232426018730533e-09 1072.778716343384 3.049973588674538e-10 2.8526153638665073e-09 935.2918249715732 3.4257989789483696e-10 2.063403680105677e-09 602.3131225110843 4.2235863375172727e-10 2.211190437114416e-09 523.5338549783754 +r_2552 CL synthase (1-16:0, 2-16:1, 3-16:0, 4-18:1), mitochondrial membrane 1.9370962322081027e-10 2.8045908407701632e-09 1447.8324794288612 -2.792548924356171e-10 3.7290143485648394e-09 -1335.3443214695235 1.8321617871187447e-10 3.088511138934513e-09 1685.7196567730523 3.5632214262529165e-10 2.5614221343824953e-09 718.8501156595497 6.054945288938349e-11 3.146247891006959e-09 5196.162377808388 -1.1140675505190564e-10 3.5524326436978043e-09 -3188.704887816442 -1.3536676266343354e-10 3.5007795798950446e-09 -2586.1441250531625 -1.0321538076599964e-10 3.372380876875236e-09 -3267.3239703690924 -2.1230353746947512e-09 6.090073074650849e-09 -286.8568817665827 +r_2553 CL synthase (1-16:0, 2-16:1, 3-16:1, 4-18:1), mitochondrial membrane 3.377520209175131e-10 2.8714415346594833e-09 850.1626509470261 -1.5434614507990772e-10 2.6440299940889157e-09 -1713.0521742023775 -3.0896547535000635e-10 3.796193412967249e-09 -1228.67883819925 2.6090338301314084e-10 2.880485665153478e-09 1104.043049149883 -2.7142166533256275e-10 3.1096454205590353e-09 -1145.6879894789915 8.419542846931881e-11 1.990708454132697e-09 2364.390193534225 -2.692482223171181e-10 3.1730036588623246e-09 -1178.46782108934 -2.8043171462633245e-10 3.273718570079321e-09 -1167.3852846642046 -4.4632925351235805e-10 3.615404765613573e-09 -810.030876793844 +r_2554 CL synthase (1-16:1, 2-16:1, 3-16:0, 4-16:1), mitochondrial membrane 1.1920236501883798e-10 1.772017690698228e-09 1486.5625278644343 4.12789788527442e-10 2.266535870842668e-09 549.0775047823138 3.1177679453301655e-10 2.5247072462297182e-09 809.7803590582351 2.6996106316946647e-10 1.8970467188055517e-09 702.7112341807202 2.5257284437902527e-10 2.132800957664753e-09 844.4300347919232 1.07393593182174e-10 2.540823982025999e-09 2365.899032464577 2.59721211599511e-10 1.946023119438887e-09 749.273849237869 2.2016317577983918e-10 1.8103758645155038e-09 822.2882224073026 2.355740882319928e-10 2.354781533599628e-09 999.5927613569472 +r_2555 CL synthase (1-16:1, 2-16:1, 3-16:1, 4-16:1), mitochondrial membrane -1.047246242827669e-09 5.3460454096044495e-09 -510.4859956498476 -8.366834293015917e-10 4.853933819672554e-09 -580.1398294363613 -9.584528688838071e-10 5.3303149063421334e-09 -556.1374042888201 -1.0628722610275835e-09 4.870917414053199e-09 -458.2787219739841 -1.196079935762982e-09 5.468318083279692e-09 -457.1866745504296 -6.70986760578702e-10 5.098870073390276e-09 -759.9062117101512 -1.2772050278856601e-09 5.8086271494165105e-09 -454.7920672558234 -1.4748556312702022e-09 5.498527673339916e-09 -372.8180275247939 -6.459549961856142e-10 4.972835503046475e-09 -769.842408900192 +r_2556 CL synthase (1-16:1, 2-16:1, 3-18:0, 4-16:1), mitochondrial membrane 1.1395017854712284e-10 2.5971668952730233e-09 2279.212659766912 2.0978554754546146e-10 2.108408921928318e-09 1005.0305879490654 1.8910215694981888e-10 3.2753387054018703e-09 1732.0472480232102 2.1455522022012766e-10 2.7146033258834437e-09 1265.223620799501 1.13013078161166e-10 3.2218460432512182e-09 2850.8612416136457 1.6730207784106816e-10 2.011850018701423e-09 1202.5254226744385 1.1101157552614976e-10 2.3365385915913503e-09 2104.770228255122 1.290119638511577e-10 2.3401919306383647e-09 1813.9340420693588 1.0235061247288859e-10 2.6240540998422582e-09 2563.7893476576287 +r_2557 CL synthase (1-16:1, 2-16:1, 3-18:1, 4-16:1), mitochondrial membrane 1.9040483164412488e-10 3.159105970541744e-09 1659.1522091447 2.0530462387324438e-10 2.8264179940740914e-09 1376.6947576490677 2.2715648826555727e-10 3.3791714104573782e-09 1487.596254132507 2.1288088459409708e-10 2.624545672218539e-09 1232.8705215702182 2.5347263614627087e-10 2.2973300747273588e-09 906.342439821253 1.68482928393534e-10 3.369454795901405e-09 1999.8790548269685 2.1500575965033118e-10 2.623157564251778e-09 1220.0406019438176 1.5495224936195802e-10 3.466755676064668e-09 2237.305808944122 -2.4318032841869646e-10 4.490945697607359e-09 -1846.7553386452623 +r_2558 CL synthase (1-16:1, 2-16:1, 3-16:0, 4-18:1), mitochondrial membrane 1.7927055218017043e-10 2.959141287710098e-09 1650.656648134883 -5.641372351600493e-10 4.361712850726047e-09 -773.1652120939334 4.664640147647557e-10 2.808604372151435e-09 602.1052606958017 3.3407225674020115e-10 2.571755238622199e-09 769.820057408174 3.4982309963499047e-10 2.6572834998735303e-09 759.6077853767149 2.1087562346537606e-10 2.453723947333325e-09 1163.5882360467351 -5.3970737840389706e-11 3.1524581726153433e-09 -5841.050722593902 2.6997266920238557e-10 3.2863760720620273e-09 1217.2995443469829 3.8301351129341236e-10 3.427476029265334e-09 894.8707886807871 +r_2559 CL synthase (1-16:1, 2-16:1, 3-16:1, 4-18:1), mitochondrial membrane -2.2516566488014728e-10 4.1477270807661615e-09 -1842.0779575669053 -4.1615138759139744e-10 3.7250389295659694e-09 -895.1163063820991 -3.7247812533316887e-10 4.009674336657297e-09 -1076.485856201832 -5.219452757244579e-10 3.924780750140432e-09 -751.9525384520155 -4.63249558271988e-10 4.120216395649152e-09 -889.4161520667975 -2.16877064133246e-10 3.382127694702957e-09 -1559.4676681094456 -5.735897890813953e-10 4.504721848018566e-09 -785.356004198206 -3.99343706333893e-10 4.363977510158874e-09 -1092.787351082011 -3.3512952451666556e-10 4.544953366213233e-09 -1356.1781441871196 +r_2560 CL synthase (1-18:0, 2-16:1, 3-16:0, 4-16:1), mitochondrial membrane 1.4490871212180568e-10 2.699605938967002e-09 1862.9700722878545 3.36287991718149e-10 2.992778070444081e-09 889.9449710212668 3.3450236111355064e-10 2.4336112752461952e-09 727.5318676809214 -9.167697909902777e-13 3.636933188062846e-09 -396711.7180131229 1.4538643953608158e-10 3.079343985578624e-09 2118.0407164551275 6.192983930207627e-11 2.916220896854818e-09 4708.910808940285 9.671660225811854e-11 3.232153695647714e-09 3341.880938933008 1.2139355003452655e-10 2.952379560609972e-09 2432.0728405835903 1.1527275189434092e-10 3.2298883235455863e-09 2801.9529944996057 +r_2561 CL synthase (1-18:0, 2-16:1, 3-16:1, 4-16:1), mitochondrial membrane 9.665553778454604e-11 2.8142647242650327e-09 2911.6435423889347 1.8151137079933175e-10 2.468636319201313e-09 1360.044997913927 1.2462364149353755e-10 2.684127921922768e-09 2153.787106326816 1.8864732470828358e-10 1.9344463456167742e-09 1025.43004445365 1.5620637900047235e-10 2.7060521347356524e-09 1732.3569959505112 1.4114125659957395e-10 2.2013891380811e-09 1559.7063474690256 9.274835990565788e-11 2.405651608495726e-09 2593.7403215999884 8.528362272322594e-11 3.032381146465825e-09 3555.6429823659378 1.7193210709700518e-10 1.795477704767405e-09 1044.294596909922 +r_2562 CL synthase (1-18:0, 2-16:1, 3-18:0, 4-16:1), mitochondrial membrane -8.103254038813945e-10 5.0499166776171805e-09 -623.1961448361952 -1.4375012227106044e-09 6.595224175526114e-09 -458.7978132700241 -2.090996410020626e-09 7.448850643586513e-09 -356.2345017853492 -1.0100091883804542e-09 5.476587057693085e-09 -542.2314094463604 -1.551437657693013e-09 6.621735518143643e-09 -426.81286517114455 -1.8972837155689634e-09 7.221115295084447e-09 -380.60281843081947 -1.100417167731335e-09 6.021633157922577e-09 -547.2136690067297 -1.2808546726220572e-09 6.056532768677709e-09 -472.8508938706753 -1.949249540114909e-09 7.201629607097146e-09 -369.4565246208859 +r_2563 CL synthase (1-18:0, 2-16:1, 3-18:1, 4-16:1), mitochondrial membrane 7.685600905750036e-11 3.0437202898541802e-09 3960.289282750812 3.237990832123117e-10 2.2586745847205206e-09 697.5543483054059 3.7146980025502066e-10 2.442298066581176e-09 657.4688076674053 2.515874859872462e-10 2.3406490076831516e-09 930.351920525096 1.7461439584209482e-10 2.5685307154860823e-09 1470.9730564304816 1.5034662700285894e-10 2.4599692714667993e-09 1636.198510406237 2.245562430053807e-10 3.455135375068626e-09 1538.6503304590096 1.7207242301788418e-10 2.481568505750101e-09 1442.165143157298 1.6678527205763423e-10 2.369664956228229e-09 1420.7878951142454 +r_2564 CL synthase (1-18:0, 2-16:1, 3-16:0, 4-18:1), mitochondrial membrane 2.711132755149377e-10 3.493010361755565e-09 1288.3951754561383 -8.437965070765703e-10 4.537160037198803e-09 -537.7078477035076 -9.150497677156911e-10 5.099274149775688e-09 -557.2674109852404 -1.5755467996282595e-09 5.5312620772980215e-09 -351.06936071991566 -5.617241787542035e-10 4.229344806094395e-09 -752.9219795156887 7.223495736894312e-11 3.458338457038449e-09 4787.624417599969 -5.912036663037733e-10 4.481730870045948e-09 -758.0688560451409 -6.05329734322312e-10 4.525270509239446e-09 -747.5711587678154 3.4508279535148046e-11 3.6567127097826605e-09 10596.624227696298 +r_2565 CL synthase (1-18:0, 2-16:1, 3-16:1, 4-18:1), mitochondrial membrane 3.3746778937258583e-10 3.743144261410436e-09 1109.185640611693 -4.0452884023055824e-10 3.149866294356123e-09 -778.6506130343834 -1.0323274020750276e-10 2.4077527858623312e-09 -2332.353845323328 -4.1923615620338016e-10 3.882126622887039e-09 -925.9999562165004 -2.175482861931764e-10 2.625325805764359e-09 -1206.7784360448363 1.6506387154657548e-10 2.3886284838557077e-09 1447.0934562938062 -5.195368089839182e-10 3.865977653799335e-09 -744.1200675194125 -3.1693477772033925e-10 3.410057690731462e-09 -1075.9493531317255 2.119932278337507e-10 3.269888643728048e-09 1542.4495759328502 +r_2566 CL synthase (1-18:1, 2-16:1, 3-16:0, 4-16:1), mitochondrial membrane 1.3414698700509088e-10 2.2835884673767716e-09 1702.303211096429 5.807648557888785e-10 2.367592637609873e-09 407.6680284646128 3.8232557208630256e-10 2.1968531955720994e-09 574.6027354602905 3.503705100580825e-10 2.1760711165383082e-09 621.0771323698362 3.7644731144116466e-10 2.1487344178418235e-09 570.7928712827721 1.1209614885998814e-10 2.182484851174195e-09 1946.97576443968 3.0648267990690874e-10 2.21601715596576e-09 723.0480876240233 2.663727539830214e-10 1.822326486170737e-09 684.1264577258124 3.8408449889378916e-10 2.2984593852757034e-09 598.4254485394622 +r_2567 CL synthase (1-18:1, 2-16:1, 3-16:1, 4-16:1), mitochondrial membrane 2.3278294792474463e-10 3.290207156972693e-09 1413.4227555346408 -4.4023010833236905e-11 2.950079773662943e-09 -6701.222196814544 8.339619168796735e-11 3.275882658269949e-09 3928.096225936661 1.7139914526035646e-10 2.35609334709052e-09 1374.6237436082886 1.4925431642985315e-10 2.377732380730307e-09 1593.0744501099896 1.6311636943579586e-10 2.277796432425442e-09 1396.4241849571113 1.616518367878084e-10 2.735918247204022e-09 1692.4758181345717 1.3958710264172566e-10 2.629268668182121e-09 1883.6043004134788 1.722791083090056e-10 2.992009462911681e-09 1736.7221668834695 +r_2568 CL synthase (1-18:1, 2-16:1, 3-18:0, 4-16:1), mitochondrial membrane 2.2324247075946992e-10 2.381955006218452e-09 1066.9811161447242 2.638175421060585e-10 2.280062877189658e-09 864.2574936404495 3.802902215274711e-10 2.835577607167051e-09 745.6351614242641 1.7765535750843754e-10 2.1949915305330427e-09 1235.5335416376588 1.646244045786539e-10 2.6011306719664966e-09 1580.039532184752 3.320411385993892e-10 2.005648458730711e-09 604.0361345557681 2.3806219075756777e-10 2.975173807127682e-09 1249.746462325666 2.2139866379995183e-10 1.805574850976097e-09 815.5310515367662 3.0561057082864017e-10 1.9438943480785063e-09 636.069080597501 +r_2569 CL synthase (1-18:1, 2-16:1, 3-18:1, 4-16:1), mitochondrial membrane 5.5946635182406296e-11 4.875608653475356e-09 8714.748684311586 -4.42950371939574e-10 5.33207284509964e-09 -1203.7630359698685 -4.1796113476374927e-10 5.213412337761116e-09 -1247.3438088227924 -3.864305588689575e-10 4.751300320601872e-09 -1229.535348992181 -5.44556230028215e-10 5.0065262170472214e-09 -919.377272901242 -1.0357639112310408e-10 4.794454306748543e-09 -4628.906505392883 -3.9045702347360284e-10 5.315861316317137e-09 -1361.445945836986 -9.373354984521294e-11 3.975400317629271e-09 -4241.171196646297 -1.996359215228621e-11 4.1544513741262325e-09 -20810.13949010408 +r_2570 CL synthase (1-18:1, 2-16:1, 3-16:0, 4-18:1), mitochondrial membrane 3.987175843668803e-10 2.0631631695994068e-09 517.4497565427124 -1.1290416845582631e-10 3.7199539002260645e-09 -3294.788802843444 4.0915611003788126e-10 2.88592000316876e-09 705.3346955766027 1.9188265072938688e-10 2.879682896846616e-09 1500.75209295907 4.43528156863553e-10 2.9972856033735705e-09 675.7824857319384 3.6809047300249025e-10 2.523998011833404e-09 685.7004451229924 2.0009952013739867e-10 3.176223231185982e-09 1587.3217631931466 3.863412785992534e-10 2.821958270702263e-09 730.4314674667323 4.847690737358216e-10 4.689941643656324e-09 967.4589196694794 +r_2571 CL synthase (1-18:1, 2-16:1, 3-16:1, 4-18:1), mitochondrial membrane 9.065282034262839e-11 4.129301653545946e-09 4555.0724598958695 -2.707854669601201e-10 3.5640418507461304e-09 -1316.186533478558 -2.9084164877507446e-10 4.766973446076699e-09 -1639.027101570067 -4.3762705250293646e-10 4.082759016498745e-09 -932.9311323758602 -3.7798935202821455e-10 4.183223283871828e-09 -1106.7040014290071 -1.4492772521610875e-10 3.8467097018584934e-09 -2654.2262331948414 -3.55029863086117e-10 4.226238269586619e-09 -1190.3895162085255 -3.5870087031587004e-10 4.630687728642131e-09 -1290.960828883513 -2.1390870155816249e-10 5.261877611246945e-09 -2459.8707639839613 +r_2572 CL synthase (1-16:0, 2-18:1, 3-16:0, 4-16:1), mitochondrial membrane -3.5275549613607887e-11 3.682486642064935e-09 -10439.204158124245 3.708528299635157e-11 3.6416575507787004e-09 9819.683865259884 9.564528489539244e-11 3.478593899398275e-09 3636.973744396102 1.3586780510457314e-10 3.255995722749717e-09 2396.443896509317 2.377451733098384e-10 2.961486153456338e-09 1245.655637179569 -9.126299944219792e-11 3.1093298889854222e-09 -3406.999449930131 2.8524100020734807e-10 3.023318713695116e-09 1059.91730203491 -2.705421422510807e-10 3.5849371986711953e-09 -1325.0938167496806 1.0897351414579619e-10 2.838454123376077e-09 2604.7192711235275 +r_2573 CL synthase (1-16:0, 2-18:1, 3-16:1, 4-16:1), mitochondrial membrane 2.5496311928895705e-10 2.885052901133841e-09 1131.556951915123 2.0557365719026302e-10 2.998764710950604e-09 1458.7300493346677 3.3573978642860755e-10 2.798371970237342e-09 833.4942962836471 2.0140954278828571e-10 2.7274825507385686e-09 1354.197280317347 1.5245417522285403e-10 2.6923140112437753e-09 1765.9824713283265 1.2741366632918408e-10 3.1294355233196042e-09 2456.122340310371 2.9281825014123115e-10 3.186823601160367e-09 1088.3282034583938 1.8646762687735766e-10 2.88372995079206e-09 1546.5043445255662 2.1998742464081384e-10 3.157331307777645e-09 1435.2326333802046 +r_2574 CL synthase (1-16:0, 2-18:1, 3-18:0, 4-16:1), mitochondrial membrane -3.320993885303221e-10 5.169217530645775e-09 -1556.5272653833274 1.6196942679857668e-10 3.072348630876808e-09 1896.8694843240664 -1.3873381889401437e-10 3.8673673280999975e-09 -2787.616861505464 3.492604554618612e-11 3.256493536113273e-09 9323.96864628403 -2.0984842299917732e-10 3.53013068048193e-09 -1682.2288345220345 -7.789000545477669e-11 2.960551928271186e-09 -3800.939428602424 -2.609097411343718e-10 3.741209781178027e-09 -1433.9095830275105 -5.1058930391876956e-11 3.621660466520915e-09 -7093.098971570094 6.298548466097896e-11 3.076303833925605e-09 4884.147276922441 +r_2575 CL synthase (1-16:0, 2-18:1, 3-18:1, 4-16:1), mitochondrial membrane 4.2530936387592055e-10 3.3125888456090078e-09 778.8657215116995 3.2508861488935885e-10 3.106301291699233e-09 955.5244783815136 4.751204367136781e-10 3.166704904996978e-09 666.5057236646145 4.2063226133936357e-10 3.841967238384184e-09 913.37911793801 4.734088718826171e-10 3.239488693586043e-09 684.2898149972316 3.0163430972363657e-10 3.2154720460030675e-09 1066.0166772636533 4.885095912987213e-10 3.1904204900286843e-09 653.0927021405722 3.070298258125503e-10 2.791145735139919e-09 909.079672554023 4.789976384146581e-10 3.642019729641217e-09 760.3418968192065 +r_2576 CL synthase (1-16:0, 2-18:1, 3-16:0, 4-18:1), mitochondrial membrane -2.810214443828856e-09 7.845381917298202e-09 -279.1737810090051 -2.1876453125014607e-09 7.129527356631206e-09 -325.89960154367776 -2.7882640627577262e-09 8.317492664259237e-09 -298.3036210721318 -2.147978744827558e-09 7.466537234958674e-09 -347.6075940201212 -2.587160100763058e-09 7.573543792707765e-09 -292.73579901274843 -1.9149477189898124e-09 6.828834624742712e-09 -356.6068439897205 -2.476885130350012e-09 7.890544962431091e-09 -318.5672547243265 -1.2765516922974443e-09 6.0237435471882105e-09 -471.87619455872704 -2.126040121867917e-09 7.611375258012224e-09 -358.0071316492818 +r_2577 CL synthase (1-16:0, 2-18:1, 3-16:1, 4-18:1), mitochondrial membrane -5.332979534623837e-10 4.755751666089325e-09 -891.7625944770798 -9.00306656761475e-10 5.394392820843903e-09 -599.1728240962102 -1.2300591058483927e-09 6.563709903367362e-09 -533.6093096794938 -5.805919515986176e-10 4.596247648600468e-09 -791.6485297367688 -6.322083940679965e-10 4.988645967781808e-09 -789.0825263615938 -7.587855142223062e-10 4.834196414882323e-09 -637.0965607899067 -8.40724861787668e-10 5.889813985983936e-09 -700.5637936601734 -6.95585333168805e-10 5.205979799005606e-09 -748.4315080781347 -1.0488371629241772e-09 6.102168371410312e-09 -581.8032185661076 +r_2578 CL synthase (1-16:1, 2-18:1, 3-16:0, 4-16:1), mitochondrial membrane -1.2043353188439834e-10 3.805133456893818e-09 -3159.5299061280434 -2.6635370298508075e-10 3.1392495341400324e-09 -1178.6017986451163 -2.1788952790277546e-10 3.174042505223846e-09 -1456.7209979178697 -3.46920791887911e-10 3.4982915463751883e-09 -1008.3833624781632 2.8532231797067594e-10 3.055120649431912e-09 1070.7611907687865 9.894987249533219e-11 2.384945447128244e-09 2410.256210527962 3.0381201858643277e-10 2.8081210632568592e-09 924.295581301358 -2.5050771848011877e-10 3.1328990341703e-09 -1250.619762607809 3.19388718339457e-10 2.5750070416636122e-09 806.2298051889261 +r_2579 CL synthase (1-16:1, 2-18:1, 3-16:1, 4-16:1), mitochondrial membrane -4.1427196573897015e-10 4.623388012150125e-09 -1116.0272464739476 -4.2188715019509846e-10 4.085416132247407e-09 -968.367045632496 -5.633341161267063e-10 4.403810800378893e-09 -781.740475911169 -5.572105810087901e-10 4.628105131513264e-09 -830.5845741720141 -6.918764743580056e-10 4.866369804859163e-09 -703.3581838975927 -1.2447132763901722e-10 3.368114298650491e-09 -2705.935866947972 -7.709094844932069e-10 5.007398651879495e-09 -649.544304824754 -4.1472151209514597e-10 4.793162243692014e-09 -1155.7544289123734 -4.139063862316671e-10 4.582133036734028e-09 -1107.045744921019 +r_2580 CL synthase (1-16:1, 2-18:1, 3-18:0, 4-16:1), mitochondrial membrane -2.823077759056617e-10 4.521877734542033e-09 -1601.754581514999 9.44183055828736e-11 2.847130482067978e-09 3015.4433131284827 -1.0847081335725107e-10 2.69622134036955e-09 -2485.6652742977826 9.247746891890896e-11 3.074596984144494e-09 3324.698459081452 -3.4285180894061775e-10 3.200408695542706e-09 -933.4670583864468 9.135053043117726e-11 2.856748744302486e-09 3127.23826650874 -3.0532945626891085e-10 3.226645816362927e-09 -1056.7751489791222 1.8499682864249976e-10 3.271871658853982e-09 1768.6095933983634 3.384042909512376e-11 3.391684332743488e-09 10022.58075159045 +r_2581 CL synthase (1-16:1, 2-18:1, 3-18:1, 4-16:1), mitochondrial membrane 9.080267513591115e-11 4.413387189629275e-09 4860.415382061628 -3.8939633431528406e-10 4.02769043208367e-09 -1034.3421540333643 -2.987700932446842e-10 4.254180289281244e-09 -1423.89763415751 -5.089806850010506e-10 4.3623846454030155e-09 -857.0825522375195 -3.55553632202495e-10 4.1742740992221785e-09 -1174.0209411909043 -3.583923321164799e-11 3.734667119323378e-09 -10420.611114273466 -6.62302447285179e-10 5.080978390170399e-09 -767.1688985897094 -6.205380783475348e-11 4.420779014503263e-09 -7124.105947334611 -1.2227830367464827e-10 4.307832248674482e-09 -3522.973511422384 +r_2582 CL synthase (1-16:1, 2-18:1, 3-16:0, 4-18:1), mitochondrial membrane -7.727922231132979e-10 5.448474381629782e-09 -705.0374238601764 -8.83174555433714e-10 5.7136904636667795e-09 -646.9491708647414 -1.3335032990102244e-09 6.628336973934855e-09 -497.0619104470646 -8.11707529307724e-10 5.028651708588524e-09 -619.5152227893312 -5.780997206679501e-10 4.7582940919242735e-09 -823.0922662315818 -2.336584226182066e-10 4.2099567473699e-09 -1801.7568980378203 -1.085498097963623e-09 6.205632701835322e-09 -571.6852672037832 -2.176556909634551e-09 7.986826694413667e-09 -366.9477539989834 -1.944247221782921e-09 7.520636768000118e-09 -386.8148393753915 +r_2583 CL synthase (1-16:1, 2-18:1, 3-16:1, 4-18:1), mitochondrial membrane -2.12652487735861e-09 7.384284265885681e-09 -347.2465497350689 -2.285677942296467e-09 7.366714017601128e-09 -322.298862901028 -2.2366035626914824e-09 7.720930960498886e-09 -345.20784502407207 -1.7458918021309732e-09 6.418855389574695e-09 -367.6548215496555 -2.0746531355758675e-09 7.214947714057346e-09 -347.7664574543287 -4.2716455652649255e-09 9.853796147339146e-09 -230.6791609178843 -2.5266356042967704e-09 8.308373133301873e-09 -328.8314753094091 -2.5668315727385354e-09 8.247751691838651e-09 -321.3203304585809 -1.6752276535436547e-09 7.024667861515586e-09 -419.3261642175088 +r_2584 CL (1-16:0, 2-16:1, 3-16:0, 4-16:1) phospholipase (1-position), mitochondrial membrane -1.7358228752376086e-10 2.8252902245958043e-09 -1627.637396015457 2.1027056184283435e-10 2.271122038980217e-09 1080.095101794495 2.1570201395924696e-10 1.87741719086399e-09 870.3753647931608 1.9154490541478227e-10 1.6233036136980914e-09 847.4793992473449 2.0373686530607599e-10 2.319350929727445e-09 1138.4051316599284 4.007509407856637e-11 1.9543115006471238e-09 4876.623612700042 2.2106387269757627e-10 2.7671241034611167e-09 1251.730583425835 1.3272050486723967e-10 1.654067607588462e-09 1246.278869450524 1.9453945388453863e-10 1.3901081564882435e-09 714.5636161358243 +r_2585 CL (1-16:0, 2-16:1, 3-16:1, 4-16:1) phospholipase (1-position), mitochondrial membrane 3.312813102284872e-10 3.056400490156984e-09 922.5997349651147 2.6486385816245625e-10 2.340538394375988e-09 883.676017790393 -1.6695648741927588e-11 4.2328707683100655e-09 -25353.137417656053 3.5933603856989143e-10 2.785652201072828e-09 775.2220490211182 3.270932479376837e-10 2.977319600407373e-09 910.2357261054184 2.3641851584112367e-10 3.827505178182274e-09 1618.953221394219 4.4023990523299927e-10 3.013066981944068e-09 684.4147806976713 3.4877121494401663e-10 2.770869708832632e-09 794.4662833707198 3.3972517549687714e-11 3.324484040363916e-09 9785.804173922566 +r_2586 CL (1-16:0, 2-16:1, 3-18:0, 4-16:1) phospholipase (1-position), mitochondrial membrane -5.7963907051941294e-11 2.6189487169184276e-09 -4518.240488122367 1.64665272146934e-10 2.0647712246742956e-09 1253.9202697408234 2.9115357653006837e-10 2.329015856251297e-09 799.9269265410421 1.9190095723638677e-10 2.041314476320115e-09 1063.7333475130038 2.048436981522469e-10 2.619274322173581e-09 1278.669710515988 4.634985904071132e-11 2.657008559435966e-09 5732.506235029081 2.3460506625558983e-10 3.0795959885261926e-09 1312.672414828048 -9.9465973618895e-11 2.051098390832682e-09 -2062.1106054734737 6.2083099144377604e-12 2.5603339382659364e-09 41240.433766229056 +r_2587 CL (1-16:0, 2-16:1, 3-18:1, 4-16:1) phospholipase (1-position), mitochondrial membrane 3.5052949612992836e-10 2.770664187788484e-09 790.4225517048931 1.5142878331250386e-10 2.938527006158051e-09 1940.533986919652 3.6992287524267617e-10 3.123411909082997e-09 844.341379817072 3.832888678992161e-10 2.746954306195002e-09 716.6799080940959 3.955326020091651e-10 2.8779809879552998e-09 727.6216861356506 4.827165757220746e-10 3.0467823086795843e-09 631.1741634564829 3.5774483580644803e-10 3.313442279727605e-09 926.2026864086696 3.1913054709038913e-10 2.4300760619464968e-09 761.4677078400184 1.4419178308240435e-10 2.677564414934175e-09 1856.9466010445065 +r_2588 CL (1-16:0, 2-16:1, 3-16:0, 4-18:1) phospholipase (1-position), mitochondrial membrane 3.1432301070295966e-11 1.4350657664375495e-09 4565.5765488760535 2.650244109293127e-11 4.377855156362434e-09 16518.686490091266 4.821297750314857e-10 2.229825664153546e-09 462.4949089709149 2.0281752179290123e-10 1.2997148847787482e-09 640.8296843829396 4.338945212755328e-10 2.8793712616362447e-09 663.610882472466 -9.861311089963647e-11 3.1536790866450742e-09 -3198.032247309114 3.751129278366074e-10 3.656603322640891e-09 974.8006670230365 4.781006773515277e-11 2.588755484776185e-09 5414.6660053208425 3.5988913981259037e-10 2.139108435379452e-09 594.3798238794805 +r_2589 CL (1-16:0, 2-16:1, 3-16:1, 4-18:1) phospholipase (1-position), mitochondrial membrane 1.1351942208448072e-10 2.912524005433506e-09 2565.661410138273 9.98872594777362e-10 2.961567298777797e-09 296.49099537443 9.820660727466902e-10 3.085297158152394e-09 314.1639084958189 5.7178757822616117e-11 3.4794128229279227e-09 6085.149372642891 9.657311982453523e-10 3.311119514579673e-09 342.8614008324141 -5.374039312691188e-11 4.029785551188128e-09 -7498.615690569092 1.047693512023041e-09 3.192306302175967e-09 304.69848916137613 3.5300211882123206e-10 3.6584206201103915e-09 1036.373558415692 1.2922945712753787e-09 3.683394829292581e-09 285.0274938211186 +r_2590 CL (1-18:0, 2-16:1, 3-16:0, 4-16:1) phospholipase (1-position), mitochondrial membrane -2.1518901764485016e-10 2.3242592499150913e-09 -1080.101240924418 3.1539590370498136e-10 2.495752165016954e-09 791.3077296499891 1.9453475357373772e-10 2.4056235729073395e-09 1236.6035007701057 1.0571234388163676e-10 2.342736783157938e-09 2216.143070085588 8.149990067491102e-11 2.276289418101789e-09 2792.996554905648 -3.7437684682116247e-10 2.644052651563752e-09 -706.2543194148967 -1.1308704510007391e-10 3.123559597480597e-09 -2762.0843702445945 8.984211383489169e-11 2.2921068959697797e-09 2551.261093636024 8.602854135907778e-11 3.051036681658974e-09 3546.540059216089 +r_2591 CL (1-18:0, 2-16:1, 3-16:1, 4-16:1) phospholipase (1-position), mitochondrial membrane 6.581319850847419e-11 3.050542846661462e-09 4635.153610211894 1.6908671474641956e-11 3.7079470731746396e-09 21929.26321110131 2.0013993430548968e-11 2.875575332122952e-09 14367.82390331821 -1.8291606122709928e-10 4.873356340007531e-09 -2664.2582982130903 1.2702356642384636e-10 3.161922531430498e-09 2489.2408711623966 -1.467923114127806e-10 3.606296563936935e-09 -2456.733959175841 2.0005198051088968e-10 3.0631569128675995e-09 1531.1804987108626 1.9665685691171414e-10 3.055074547761929e-09 1553.5052251615382 2.1420961921140187e-10 2.9758025945080042e-09 1389.2011971559534 +r_2592 CL (1-18:0, 2-16:1, 3-18:0, 4-16:1) phospholipase (1-position), mitochondrial membrane -1.0420376217968591e-10 3.0093266845583604e-09 -2887.925178142 2.3164458294877503e-10 3.1388572379971635e-09 1355.0315738189647 1.3039765669275927e-10 2.729657933407705e-09 2093.3335787155124 -5.3854873348395325e-11 2.759895629087993e-09 -5124.690594356819 -1.999814707369929e-11 3.255831832261234e-09 -16280.667505156838 1.1064113314663274e-11 2.818647735312349e-09 25475.586295530746 1.039275612295201e-10 2.626145848216429e-09 2526.9002920377256 8.4860139625453e-11 2.652297503938348e-09 3125.492740932064 2.8934725147860757e-10 3.4986037955837587e-09 1209.1366956849845 +r_2593 CL (1-18:0, 2-16:1, 3-18:1, 4-16:1) phospholipase (1-position), mitochondrial membrane 2.5010312194564017e-11 3.661368709476489e-09 14639.43624930954 1.7276207253328948e-10 3.1573349262342844e-09 1827.5625430610053 2.1560693271967927e-10 3.006275768779805e-09 1394.3316807388594 -8.555702653054425e-11 4.690350815626192e-09 -5482.133970553214 1.0361524926751095e-10 3.384992943496217e-09 3266.886840909814 4.370201684326982e-10 3.947716071815647e-09 903.325831842839 -6.651275202480205e-10 5.3852427570079895e-09 -809.655681515009 1.088376312102607e-10 2.844660729845901e-09 2613.6738719996324 2.7228071331064205e-10 2.8980731289456927e-09 1064.369596255359 +r_2594 CL (1-18:0, 2-16:1, 3-16:0, 4-18:1) phospholipase (1-position), mitochondrial membrane -5.951353899147335e-11 3.0716967887639887e-09 -5161.341168442493 1.1006655982331287e-09 4.868181307882754e-09 442.294309524848 7.935118255134847e-10 3.172344812248128e-09 399.7854487165697 6.652960942412549e-10 3.6970113300862387e-09 555.6941280863133 6.45169444019812e-10 3.254159199969617e-09 504.3883014195705 1.3952368507414087e-10 3.6038616313455644e-09 2582.974804192224 7.726120639456269e-10 3.981470919633907e-09 515.3260097054485 5.283169628261332e-10 4.4219279594340396e-09 836.9839074974537 1.8813748746101395e-10 2.776551176736125e-09 1475.8096401768337 +r_2595 CL (1-18:0, 2-16:1, 3-16:1, 4-18:1) phospholipase (1-position), mitochondrial membrane -6.733641704608652e-10 4.459047472877621e-09 -662.204445749727 9.572045592348648e-10 3.0853460918791563e-09 322.32881280312824 8.752162933522474e-10 3.026016709449526e-09 345.7450155388787 1.842177419376585e-09 4.389578685569972e-09 238.2820807268095 9.783791341373198e-10 3.291035431621353e-09 336.3762898033599 1.0114558404606291e-10 3.531093750616848e-09 3491.1002629721784 8.286056048635893e-10 3.320385740724992e-09 400.7196815029529 9.400536075680704e-10 3.826097104627695e-09 407.0083954601112 -5.604324325286535e-10 4.570456256679929e-09 -815.523155228218 +r_2596 CL (1-16:0, 2-18:1, 3-16:0, 4-16:1) phospholipase (1-position), mitochondrial membrane -3.0796622764975456e-10 3.973285084462746e-09 -1290.1690924959166 -4.022493978250165e-10 2.85379889727915e-09 -709.4600794208242 -4.113441738974087e-10 2.9649192477574227e-09 -720.787952255497 -1.0072588073736259e-10 3.129756309594871e-09 -3107.201730760285 2.658562830139976e-10 1.639638693408649e-09 616.7387412552972 -1.7435466788379258e-10 2.2650264442734167e-09 -1299.0913703457927 1.609092976673695e-10 1.8048308077802742e-09 1121.6448234776385 -7.461447767698628e-10 3.409483950795602e-09 -456.9467021608872 2.0171317399013003e-10 1.6458981020729195e-09 815.9596468168482 +r_2597 CL (1-16:0, 2-18:1, 3-16:1, 4-16:1) phospholipase (1-position), mitochondrial membrane -4.907690269222413e-10 4.42613696238059e-09 -901.8778120816244 1.19422321947203e-10 2.9281446205222567e-09 2451.9240396421023 4.4958226667292845e-11 2.909030911563498e-09 6470.519696186817 3.64032566699012e-12 3.7109052652766355e-09 101938.82648814969 1.9966672503485188e-11 3.033340748436043e-09 15192.019340761826 -3.521268859929444e-11 3.160034683919123e-09 -8974.136340110197 -2.9239212687200416e-11 3.37564000261491e-09 -11544.907308987187 1.6640053266081742e-11 2.9478939706282904e-09 17715.652248764916 1.6514428907492188e-10 2.823813008365137e-09 1709.906545471907 +r_2598 CL (1-16:0, 2-18:1, 3-18:0, 4-16:1) phospholipase (1-position), mitochondrial membrane -5.418763615444973e-10 5.7704273660893034e-09 -1064.8974149088162 -1.975767595828481e-12 2.704503044827231e-09 -136883.66235671437 -9.946569178770214e-10 4.195639366091483e-09 -421.81774345334907 8.442633488883354e-11 2.7268576507351484e-09 3229.866195572362 -8.62370903935688e-10 3.83645849113326e-09 -444.87336871228285 -4.96907567841618e-10 3.79170975968268e-09 -763.0613830561001 -9.405534037380506e-10 3.899556093598286e-09 -414.6023052067265 1.2335883867566368e-10 4.287786549706279e-09 3475.8648798403256 9.962644306660611e-11 2.526932335422041e-09 2536.40726060313 +r_2599 CL (1-16:0, 2-18:1, 3-18:1, 4-16:1) phospholipase (1-position), mitochondrial membrane -1.8698512095078447e-10 3.7442596110809755e-09 -2002.4371950249904 3.1763598585459495e-11 3.334822407374364e-09 10498.880970309689 -4.1136619928562167e-10 3.897813650878253e-09 -947.5289067617108 1.9161445046876526e-10 3.559665479676108e-09 1857.7228757892465 -1.9216566506000776e-10 3.6624465368215405e-09 -1905.879770810184 -5.760972458231257e-11 3.237300037297982e-09 -5619.363850060659 -2.1977281024983663e-10 3.8907363870086556e-09 -1770.3447403642358 -4.1781343940741236e-10 4.686490418783864e-09 -1121.6705775263586 1.3367563305479374e-10 2.3928757278708796e-09 1790.0612648604688 +r_2600 CL (1-16:0, 2-18:1, 3-16:0, 4-18:1) phospholipase (1-position), mitochondrial membrane -3.2415446014288235e-10 4.347423002581626e-09 -1341.157854396126 5.990877733883758e-11 4.960158491543468e-09 8279.518814896433 6.168899534418037e-11 4.452807476262287e-09 7218.155282670456 -1.5621174714080302e-10 4.774980661010565e-09 -3056.7359679465 1.982829823550475e-10 4.149249719458774e-09 2092.589928887133 1.7718048244165337e-11 4.083006227064878e-09 23044.33406433148 -1.6911066831663628e-10 3.798377170539759e-09 -2246.089621872834 3.7884508337387026e-10 4.849338075853254e-09 1280.0319414644732 3.970062488520534e-10 3.6158592520564845e-09 910.781445509175 +r_2601 CL (1-16:0, 2-18:1, 3-16:1, 4-18:1) phospholipase (1-position), mitochondrial membrane -2.4134066593502597e-10 4.246272395183923e-09 -1759.4516774587462 6.47925027306434e-10 3.9470457344594e-09 609.1824776190745 1.5856399085510539e-10 4.261389167936867e-09 2687.488593693945 4.6016270859326875e-10 3.968143649569387e-09 862.3349036040146 2.897247337015034e-10 4.082695882188799e-09 1409.163736222501 -1.0480720663339732e-10 6.362540846230024e-09 -6070.709305787917 3.3043112785393567e-10 4.576186693593518e-09 1384.913922400308 1.2256881598138036e-10 3.68478741790982e-09 3006.3008999528743 1.3098578989677922e-10 3.894980966724094e-09 2973.590470991897 +r_2602 CL (1-16:0, 2-16:1, 3-16:0, 4-16:1) phospholipase (3-position), mitochondrial membrane -5.52569828217882e-10 3.7590196556097325e-09 -680.2795707708322 3.11646880190836e-10 2.696201592265415e-09 865.1463446752313 1.939752090638999e-10 2.800390894645413e-09 1443.6849472464803 1.1332671638489544e-10 3.3873724546252317e-09 2989.032562384126 1.0340240615585204e-10 2.9967776254741082e-09 2898.1701073350764 -2.529310343156029e-10 3.2786329538256193e-09 -1296.2557017556803 2.1406411475951984e-10 3.465257682882308e-09 1618.7942975753724 -2.502420523445527e-11 3.097068748911594e-09 -12376.292153515866 1.5735568564662528e-10 2.30813858702334e-09 1466.8288454519163 +r_2603 CL (1-16:0, 2-16:1, 3-18:0, 4-16:1) phospholipase (3-position), mitochondrial membrane -2.6146227336208126e-10 3.0086779554250067e-09 -1150.7120766361934 3.182132506837553e-10 2.5319048738743232e-09 795.6629299483714 1.8471998425848184e-10 1.995112541455891e-09 1080.0740101104038 1.191183352759222e-10 2.3610438847788903e-09 1982.0994637893805 6.364992698306459e-11 2.464933767289292e-09 3872.641940257277 -5.379996413160891e-10 3.011829454922253e-09 -559.8199745179243 -3.621851656207715e-11 3.097074440750822e-09 -8551.080316728476 1.5890586987942887e-10 2.067879753670691e-09 1301.3237051845294 1.0073983442964274e-10 2.500725142645549e-09 2482.359790249675 +r_2604 CL (1-16:0, 2-16:1, 3-16:0, 4-18:1) phospholipase (3-position), mitochondrial membrane -2.035237698469844e-11 2.468291224489021e-09 -12127.778619395467 -5.150420875105548e-10 3.1160116061716876e-09 -605.0013545947022 -4.837566943372663e-10 2.745982144434388e-09 -567.6370325368438 2.559020310751945e-10 2.3619521340917315e-09 922.9907727452515 -5.96921601186033e-10 3.3228242426322035e-09 -556.6600766382102 -2.2013470047493675e-10 2.6973330314102407e-09 -1225.3102421339263 -7.06298862371986e-10 3.3009466568910204e-09 -467.3583425867834 -3.4847169687321547e-10 3.048342335446794e-09 -874.774727129668 -3.7312792453053324e-09 6.46126060805976e-09 -173.16475619425353 +r_2605 CL (1-16:1, 2-16:1, 3-16:0, 4-16:1) phospholipase (3-position), mitochondrial membrane 2.758872465556584e-10 3.379163801247044e-09 1224.8350887670772 1.6402417639440775e-10 3.095764507335565e-09 1887.383052539511 3.577180626406333e-10 2.953481903399431e-09 825.6451691584061 2.5406835160900115e-10 2.899428787820504e-09 1141.2002988402835 3.81669678293554e-10 3.084995072486626e-09 808.2892741911397 3.931498580688993e-10 2.7528926649562837e-09 700.2145895405208 3.6663869979052927e-10 3.713364677085798e-09 1012.8130716171928 2.8721557779705453e-10 2.7307865600603844e-09 950.7794044478846 1.2613908249949088e-10 3.04085557373842e-09 2410.7164199095023 +r_2606 CL (1-16:1, 2-16:1, 3-18:0, 4-16:1) phospholipase (3-position), mitochondrial membrane -2.0550826990134056e-10 3.7487136135847896e-09 -1824.1181317834328 1.5499534693624264e-10 2.98154236975078e-09 1923.63346944682 -1.0107158977940795e-11 3.730827478560654e-09 -36912.72183116251 9.425507284221403e-11 3.481152051406736e-09 3693.331240891718 -2.2613968096857807e-10 3.769320579111855e-09 -1666.8107795003027 2.9344953012530586e-11 2.8500937188263917e-09 9712.38126573034 9.535571251808032e-11 3.39689173466152e-09 3562.336901438852 2.3736708730062474e-10 2.880349118366368e-09 1213.4576664027622 2.4927829458757994e-10 3.2528059547098477e-09 1304.8893647525442 +r_2607 CL (1-16:1, 2-16:1, 3-16:0, 4-18:1) phospholipase (3-position), mitochondrial membrane -4.455686000681e-10 4.339466293006875e-09 -973.916539976928 -2.9202707773133425e-11 3.541550071591442e-09 -12127.471531423118 -1.6606731735784766e-10 3.6279825135982244e-09 -2184.6457035134263 2.0355624490631665e-11 3.635114378389632e-09 17858.034176562025 -2.8706750843507825e-11 3.216610659433347e-09 -11205.066978734028 -1.3600366537797678e-10 3.4213021854670567e-09 -2515.595573074218 1.225305543025161e-10 3.538554629312149e-09 2887.8957166681867 4.393664454994511e-11 2.927886014247352e-09 6663.881696562123 -6.655424510181922e-11 4.341942654317455e-09 -6523.915413171399 +r_2608 CL (1-18:0, 2-16:1, 3-16:0, 4-16:1) phospholipase (3-position), mitochondrial membrane -6.041341586841713e-11 2.4439260301013124e-09 -4045.3366110340185 1.5875797297249786e-10 2.303267699317152e-09 1450.8044265066007 3.3994431053440354e-10 2.8086180034639275e-09 826.1994439761878 2.0286751246410318e-10 1.9853343553772182e-09 978.635924137196 1.6342958518257718e-10 2.4167826377482123e-09 1478.7913920532055 1.2793528838564082e-10 2.3780072385340993e-09 1858.7578677791928 1.884136891605384e-10 2.662239791110915e-09 1412.9757784438616 -1.5480211370773482e-10 2.616827709561832e-09 -1690.434094783991 1.6013007742047787e-11 2.440415391095441e-09 15240.206152447374 +r_2609 CL (1-18:0, 2-16:1, 3-18:0, 4-16:1) phospholipase (3-position), mitochondrial membrane -2.3267039373330274e-10 3.436111748187348e-09 -1476.8152032810733 7.639048788371706e-11 4.139343729192809e-09 5418.66382041412 2.2649304052005223e-10 4.049607651871626e-09 1787.9611852855585 -1.9584869992054726e-10 4.121918503856412e-09 -2104.6443022234043 9.581418906281266e-11 3.7435399602778085e-09 3907.083070779492 -1.4081671001308958e-10 3.7652868770295614e-09 -2673.89209468078 -1.6377784314599612e-10 4.480043342230478e-09 -2735.4392121508417 5.825931449607636e-12 4.321757532049863e-09 74181.40033798243 2.232726839477675e-12 4.167469714073277e-09 186653.81005802832 +r_2610 CL (1-18:0, 2-16:1, 3-16:0, 4-18:1) phospholipase (3-position), mitochondrial membrane 8.476670568532874e-11 3.001160643433536e-09 3540.494607133201 -2.5964866848656233e-09 5.8626114628093454e-09 -225.79016087320144 -2.0854600637025616e-09 5.466162866927291e-09 -262.1082494968794 -3.136906897004616e-09 6.4311355899467935e-09 -205.015188563224 -1.7240713394313663e-09 4.976520387023422e-09 -288.64933098793813 -3.2988963729086783e-10 3.873709395177848e-09 -1174.244037184578 -1.8244931645137366e-09 5.382016471926028e-09 -294.9869353640708 -1.515879480917093e-09 5.42629060795867e-09 -357.96319405786886 -2.5143376640931843e-10 3.4608866452973163e-09 -1376.46056642337 +r_2611 CL (1-18:1, 2-16:1, 3-16:0, 4-16:1) phospholipase (3-position), mitochondrial membrane 4.452892795045242e-10 2.985320462852317e-09 670.4227117648326 6.258190805772522e-11 3.296044841557982e-09 5266.769492738584 2.7392217369311325e-10 3.108892556774116e-09 1134.954689815342 4.4509344067829816e-10 3.7803516552809305e-09 849.3388825321445 2.8783971430694097e-10 3.400544082032865e-09 1181.401979299722 3.703536924724191e-10 2.739886882247574e-09 739.8027717657004 3.756350261921088e-10 3.52318046823373e-09 937.926503805822 3.6250860292807636e-10 2.575738966185958e-09 710.5318178330235 1.2739349120643408e-10 3.076009164821853e-09 2414.573253069382 +r_2612 CL (1-18:1, 2-16:1, 3-18:0, 4-16:1) phospholipase (3-position), mitochondrial membrane 1.5364531107907314e-10 3.3352118146474478e-09 2170.721508664192 1.9187055433497023e-10 3.323536651551024e-09 1732.1764994480332 -1.3799716781418283e-10 4.143977757350997e-09 -3002.9440625411835 8.492697786705628e-11 3.312127357164369e-09 3899.9708224036135 -2.3098633502395668e-10 4.419715353313063e-09 -1913.409878924081 -1.0512899824526944e-09 4.636879190134705e-09 -441.06566860997856 -1.997334926522249e-10 3.752967452562072e-09 -1878.9875462182608 8.844330229246912e-11 3.0124413863894912e-09 3406.0706783966366 1.5324003849524326e-10 3.626581084143149e-09 2366.601522522929 +r_2613 CL (1-18:1, 2-16:1, 3-16:0, 4-18:1) phospholipase (3-position), mitochondrial membrane -1.6618688243299876e-11 3.23923977777869e-09 -19491.54909434352 -4.0737681304078746e-11 3.4064086543861004e-09 -8361.812811484297 1.1258636478296167e-10 3.268237371092353e-09 2902.871388904596 -1.5225976563674754e-10 3.8770793402895045e-09 -2546.3584053709983 -7.624477629198455e-11 3.235849947351422e-09 -4244.028384265323 -3.2725110960240795e-10 3.358365128438137e-09 -1026.2349094914807 6.378496408245269e-11 3.6885686379405564e-09 5782.818397722177 -2.2702172720983727e-10 3.8024228955159605e-09 -1674.9158515569573 -3.0195430524130856e-10 3.966717771801724e-09 -1313.6814752919977 +r_2614 CL (1-16:0, 2-18:1, 3-16:0, 4-16:1) phospholipase (3-position), mitochondrial membrane -9.791316293805235e-11 2.889619563340044e-09 -2951.206432957586 3.569173149591524e-10 3.0182094573682076e-09 845.6326804188885 4.606798152198463e-10 3.06623324376837e-09 665.5887977868313 2.388446382538142e-10 2.6586824242206942e-09 1113.1430220323302 2.5213273705430964e-10 2.6016118193636987e-09 1031.8421359156184 -6.322256409756143e-11 2.666799504199226e-09 -4218.113488854983 3.0744975527688806e-10 2.7019247746786267e-09 878.8183201659352 1.3681709645042128e-10 2.8220111267890872e-09 2062.615857230756 2.2584962114770536e-10 2.373543904509307e-09 1050.9399539603444 +r_2615 CL (1-16:0, 2-18:1, 3-18:0, 4-16:1) phospholipase (3-position), mitochondrial membrane 1.519067426903953e-11 4.287233279973634e-09 28222.797777393884 5.525031948437964e-11 2.8271955346844157e-09 5117.066400826369 6.348390699029521e-10 2.9189137411483462e-09 459.787980849156 -1.1051036259652708e-10 3.040122176396824e-09 -2750.983803660384 4.2758926434071906e-10 3.2766931990716142e-09 766.3179299236621 2.36946898199869e-10 3.029708028200698e-09 1278.6443085847382 4.1687978664316056e-10 4.150362339271525e-09 995.5777354165984 4.452323059894474e-11 3.034554100097373e-09 6815.664674991703 -3.064337574036686e-11 2.9585287119825513e-09 -9654.708857957998 +r_2616 CL (1-16:0, 2-18:1, 3-16:0, 4-18:1) phospholipase (3-position), mitochondrial membrane -4.201371014035875e-10 4.786055925316386e-09 -1139.1652651782488 -2.520924010426318e-10 4.6307403090120535e-09 -1836.9218151200605 4.354034418345455e-10 3.8717313157212725e-09 889.228458876662 -8.034718060581712e-11 4.370285128415573e-09 -5439.251378161197 1.9665137502834328e-10 3.958558267086787e-09 2012.982755150449 -4.1883061593069176e-10 4.49136286025663e-09 -1072.3578194674917 -7.187420175546144e-10 6.4311019596385914e-09 -894.7719491228876 1.1847502747328286e-10 3.791786350534298e-09 3200.494172824209 1.6466609272175934e-10 3.5381573140372795e-09 2148.6860200270844 +r_2617 CL (1-16:1, 2-18:1, 3-16:0, 4-16:1) phospholipase (3-position), mitochondrial membrane -1.3998690441427092e-10 4.205150229511285e-09 -3003.959725451713 1.3705473783509039e-09 3.891444215439592e-09 283.93357843068 8.727823952022501e-10 3.033024327483093e-09 347.5120882542835 5.276766985121987e-10 3.824334852123169e-09 724.749617124653 -1.6252622181089068e-10 3.6037057982728755e-09 -2217.3073108572044 2.173544896349736e-10 3.3435056873505366e-09 1538.2731191638318 -1.7812761081230182e-10 3.884579812368874e-09 -2180.784772587652 9.80310647436525e-10 3.3891922236716963e-09 345.7263503700898 1.8589680839252028e-10 2.553292274118493e-09 1373.4997906619396 +r_2618 CL (1-16:1, 2-18:1, 3-18:0, 4-16:1) phospholipase (3-position), mitochondrial membrane 4.351852864945072e-11 4.4796208447035255e-09 10293.59443833142 -3.496326780291933e-10 4.712582508233089e-09 -1347.8667196661752 7.56582380915783e-10 2.9625777517474e-09 391.57371708305374 -4.611061649100147e-10 4.284685073110769e-09 -929.2187784882314 1.0085552288818951e-09 3.585631135470259e-09 355.5215453540767 2.508884402797962e-10 3.0065962607434437e-09 1198.3797489395777 1.1526727226853292e-09 3.755911337555874e-09 325.8436903760417 -7.954297698756167e-10 4.754143237002306e-09 -597.6823369014367 5.6318978535974124e-11 3.347208408058193e-09 5943.3045397301385 +r_2619 CL (1-16:1, 2-18:1, 3-16:0, 4-18:1) phospholipase (3-position), mitochondrial membrane 2.3650350488379887e-10 4.2831749512930625e-09 1811.040793411291 4.1526428005804415e-10 5.141631194388486e-09 1238.1587921960945 7.665809937256301e-10 4.7481190992546545e-09 619.3890975796971 3.9687258255308604e-10 4.047569398251376e-09 1019.86621807264 3.742910277203735e-10 4.112471608107566e-09 1098.7363584841055 4.0232295884117054e-10 4.241796451097781e-09 1054.3262217288377 7.507810666273716e-10 4.8268249808945875e-09 642.9071263847202 -1.957562667796872e-10 5.994376168959245e-09 -3062.1631008654163 4.42413253167777e-10 3.787905939748496e-09 856.191787345033 +r_2620 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane -5.2110295645050025e-11 3.597348896324444e-09 -6903.336186821571 -3.400015342887866 73.41330469037067 -2159.2051001750983 3.8006196946252494e-10 2.896241517257345e-09 762.0445479859886 -5.639030915800701e-10 5.536713057320522e-09 -981.8554180659872 -7.113272238573406e-10 6.244455645712982e-09 -877.8597860842357 1.0643934170285127e-09 7.328996640193227e-09 688.5608763584545 -2.283963008071366e-11 2.6178170617668327e-09 -11461.73144011374 5.670478631637735e-10 2.412255087757725e-09 425.40590388593387 0.9999999010455862 31.61011932064166 3161.01224486028 +r_2621 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 1.482555795840543e-09 6.106183518447375e-09 411.8687158742271 -0.9999827674629628 83.66835410445198 -8366.979594730956 1.8257597915106677e-10 2.366541540035556e-09 1296.195453005039 2.5515190744925967e-10 2.782133811574159e-09 1090.3833090596916 6.136754944785477e-10 4.1592775472964414e-09 677.7649726474185 -1.1084846836250104e-10 2.958833747976726e-09 -2669.2599290597595 -6.599995396392388 80.97987554322421 -1226.9686670916235 2.4657564347643203e-10 2.2213993516016198e-09 900.8997483621872 2.1097764436108816e-10 3.5729976451346796e-09 1693.5432452831328 +r_2622 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 5.4403042273322174e-11 2.291100173500122e-09 4211.345685393071 9.828553188127647e-11 2.9864646657041487e-09 3038.5598048262423 -1.6900121461566606e-10 3.599840850377535e-09 -2130.0680344600537 2.680117276016398e-10 2.7559556938684463e-09 1028.2966788545805 3.6096237753840936e-10 3.847662712942576e-09 1065.9456365457788 -6.021785627954972e-11 7.841092421448645e-09 -13021.208169629774 6.599995397015134 80.97987554330219 1226.968666977034 4.48148153362751e-10 2.081462371015738e-09 464.4585401941644 1.3999990586696398 37.39408493984494 2671.00786306092 +r_2623 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -3.7115947179998286e-10 3.064725692182904e-09 -825.7166865013968 4.39999810992303 66.1929910227969 1504.3868058378514 1.2749958027428235e-10 6.039858940564974e-09 4737.159861680941 3.3674464249120947e-10 2.319175568777637e-09 688.7045185397947 2.78534538225432e-10 3.456034169381217e-09 1240.7919647595284 1.6941211376914266e-10 3.3138037259754302e-09 1956.060669009266 -1.2489687614768698e-10 3.235753831262752e-09 -2590.740402055025 -7.092248548938228e-10 4.582121013850279e-09 -646.0745110993414 -2.399998959409937 48.9358444356277 -2038.9944022167008 +r_2624 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -2.3173913565422768e-10 3.842217924227635e-09 -1657.9926879336058 -1.5208596417815987e-09 4.863709887577082e-09 -319.80004952196174 -6.43291074319583e-10 4.761002643519601e-09 -740.1008398189532 1.2725393688215966e-10 2.3052220689569967e-09 1811.5133609514105 1.0263136085815795e-09 5.428249112031347e-09 528.9074476497956 -1.2695265658838527e-10 1.4565667431691244e-09 -1147.3306524744155 1.6048071588376052e-10 2.398977768283721e-09 1494.869807299059 4.70740927491254e-10 4.618772197333804e-09 981.1707305648748 4.978058483962951e-10 4.6814260655353395e-09 940.412026218007 +r_2625 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -6.199996504006911 78.50341033930862 -1266.184751694194 2.8987135892515486e-10 1.9178843068001953e-09 661.632909823076 4.940864116759155e-10 3.031966514420019e-09 613.6510623993372 -1.2307886261765884e-10 6.497627943818491e-09 -5279.239510039345 -4.795769239464322e-10 2.376852637816249e-09 -495.61447165913626 9.286284342950907e-10 2.3214124168795548e-09 249.9829136334499 -8.022402132726152e-11 1.444990646973366e-09 -1801.1944839797416 -1.2125226047103043e-10 2.398276958050868e-09 -1977.923503227277 -1.5967774180556038e-10 5.35450796323642e-09 -3353.3214477422944 +r_2626 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 1.9909114046758846e-09 1.078261843461542e-08 541.5920773416235 8.437560804053549e-11 2.8659503321494566e-09 3396.6573974466705 3.6941310375893765e-10 2.877655273317435e-09 778.9802917211251 1.515972179912127e-10 3.1543270397105487e-09 2080.728842856067 -4.648407094619568e-10 3.3722524500591275e-09 -725.4640958539188 -8.451839632517269e-11 1.496600547803744e-09 -1770.7394045265396 1.3583410373879222e-11 2.3728830000973715e-09 17468.978222585432 -6.699109975774256e-11 2.8215124971197307e-09 -4211.772171710961 -1.3817916950744838e-10 2.468637477761165e-09 -1786.548208793581 +r_2627 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 6.199996502985537 78.50341033922446 1266.1847519014252 6.492511907028358e-10 2.4879138544941744e-09 383.197426530851 -1.7730689085853772e-10 2.968604170001056e-09 -1674.2745618214713 1.0185737589682188e-10 2.591815604771682e-09 2544.5536780734515 -3.5636263867251794e-11 3.608944063392288e-09 -10127.167305854284 -1.0128951847988327e-10 1.706570059204478e-09 -1684.8436884843252 5.656708490805192e-11 1.999741625624006e-09 3535.168250007094 4.341667580526085e-12 2.281696820641701e-09 52553.46657298037 -2.0595037236421386e-10 3.067875597291669e-09 -1489.6188640369487 +r_2628 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 1.6924348560881515e-09 6.338711049264936e-09 374.5320551903583 4.935022921086687e-10 5.028626332557451e-09 1018.9671685354908 6.270275716513426e-10 4.486118221908964e-09 715.4578880948251 -7.240975105848337e-11 5.2932691102632405e-09 -7310.160624620865 -4.2726638600329423e-10 1.2933715706642628e-08 -3027.0847720145503 9.482766390175756e-11 4.0304016773991925e-09 4250.238286556051 1.3236477679008318e-10 2.9086037268799714e-09 2197.4152016987987 1.140355032381846e-09 7.855868017491049e-09 688.8966851913294 6.641709159484253e-10 5.7155814381030354e-09 860.5588261782403 +r_2629 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 5.212383330690526e-10 4.251419270627454e-09 815.638260063316 3.9355732392689377e-11 4.5879254022158445e-09 11657.578510895875 1.4194924191613118e-10 1.0188372062382236e-08 7177.475500997674 2.1999987959508047 46.85719502321201 2129.873666724489 1.1999990739042243 34.62366119464407 2885.3073262794446 -2.586193842722588e-09 1.4355883849774246e-08 -555.0969773658281 1.8937005854527835e-10 2.997469035363682e-09 1582.863235291754 -4.007576559906971e-11 4.426877059582703e-09 -11046.269468362858 6.217707171776515e-10 5.8025095585997385e-09 933.2233568249328 +r_2630 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 1.3456112754560047e-09 6.005254822833957e-09 446.28452008169137 -4.2838198873251176e-10 1.215544224199034e-08 -2837.524116724801 -2.28807933873394e-10 6.317329604705296e-09 -2760.9748918063547 -2.2239412548275182e-10 5.227824836917707e-09 -2350.702756005648 1.2547709426956765e-10 5.695103589583776e-09 4538.759542318337 1.1140166353361995e-09 1.0598971601402316e-08 951.4195089379116 2.599998563092591 50.92892976788354 1958.806073619736 1.4124111181066158e-10 3.815762080495962e-09 2701.594480232581 1.064272162539953e-09 7.731867729242813e-09 726.4934667454066 +r_2631 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 2.7067321086118465e-10 4.988831640065432e-09 1843.119835979618 -9.9455482248602e-11 5.300343486950103e-09 -5329.362813506046 6.252707887378933e-10 6.0630544570848675e-09 969.6685925985956 -2.1999987959584404 46.85719502305927 -2129.873666710154 -1.1999990729269376 34.62366119448308 -2885.307328615841 1.9432582696369e-09 1.3656393704509221e-08 702.757524199855 -2.599998561267373 50.92892976806983 -1958.8060750019968 1.9592096370797794e-09 1.2352545317337211e-08 630.4861452064313 7.192342326398474e-10 4.599879352311789e-09 639.5523382457177 +r_2632 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -1.354688747873731e-10 4.203518676230714e-09 -3102.9405705394693 -5.051489044313722e-10 3.347903310639467e-09 -662.7557302946306 1.731849932009008e-10 3.2058268272464204e-09 1851.099664003536 -1.660938017130754e-09 1.1906103644277869e-08 -716.8300997074826 -1.853446744731862e-10 5.101387327917622e-09 -2752.378692518429 -7.290260854780066e-10 1.3333022480871974e-08 -1828.881400331484 -1.7475111554389322e-10 1.937433558364096e-09 -1108.681654096485 -2.6254481669557902e-09 1.3290075882281884e-08 -506.2021810048432 -2.066453532363062e-09 1.2268002541061515e-08 -593.6742515101524 +r_2633 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -1.0861319036987131e-10 4.150438641758261e-09 -3821.302576256493 -1.4692300622140527e-10 4.086037863605589e-09 -2781.074229755512 6.856482480008772e-10 5.314669806997727e-09 775.13066247796 2.4184725325110082e-09 1.1441211589740814e-08 473.0759368129701 -8.02341499093271e-10 4.627534859360114e-09 -576.753771877649 6.682343272521039e-10 8.435684819520289e-09 1262.384237907875 -3.634726223668591e-10 2.5710855801747955e-09 -707.3670537914008 -3.0858201829905086e-10 2.395130860561673e-09 -776.1731787756083 1.0791373753148087e-10 3.260801988259156e-09 3021.674591993356 +r_2634 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -1.0841923433829328e-09 8.942260851530805e-09 -824.7854641390353 1.0136241826111516e-09 1.2312638035073133e-08 1214.7143138747044 -1.3681414980281303e-09 1.2323221195833514e-08 -900.727096838644 -2.1026910570471782e-10 3.712212212196315e-09 -1765.457745090426 8.764690378597724e-10 1.0728916444136588e-08 1224.106726044226 -4.2032738644831376e-10 4.602724549004985e-09 -1095.0332282407596 -6.127188496435301e-10 2.983144922381661e-09 -486.8701075733521 -3.0312680141317255e-10 2.979393186408205e-09 -982.8867564723142 2.230191611776072e-11 5.001989445542634e-09 22428.518783456308 +r_2635 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -2.1045887581985023e-09 1.0257015934607484e-08 -487.3643791287445 -8.480030562690297e-11 4.2513509325775204e-09 -5013.367465068163 -6.528130719400246e-10 9.66527133087237e-09 -1480.557260005409 -6.8449198091792e-11 3.3783736986623358e-09 -4935.592808745337 -1.1017971262035823e-10 6.209779859355944e-09 -5636.046520426796 4.836620813208272e-12 1.3163414404345997e-08 272161.38938157354 -3.5568864982049997e-10 2.2305502154031928e-09 -627.1075044224355 5.818550595933163e-10 1.194784210275282e-08 2053.405209040149 -8.850280293472406e-10 1.0712738251886549e-08 -1210.4405619546098 +r_2636 MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 2.6979605169365956e-10 3.041294053699416e-09 1127.2566943094705 2.1080914369153958e-10 1.877269337234115e-09 890.5065996477718 4.687106723578098e-10 3.546309054581672e-09 756.6094103943191 1.087530685338598e-09 6.099023858102525e-09 560.8139559026438 2.0544637407831427e-10 5.520529793120959e-09 2687.0903990822367 1.9863641393130267e-11 3.187723976780652e-09 16048.034263662805 -8.302530854023881e-11 2.6306738255463267e-09 -3168.5203846864983 6.101598582382665e-10 4.1052368384739715e-09 672.8133263841952 3.1999975332363366 56.483565425224256 1765.1127801995294 +r_2637 MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 1.3489577360907186e-10 6.962238486005973e-09 5161.198382821503 -2.3473265466853727e-10 2.252318046654018e-09 -959.524804861294 -5.158912701661279e-10 7.0368687574135954e-09 -1364.0216775033964 -3.7907507369712005e-10 4.08066385522242e-09 -1076.4790771980065 6.963426011171056e-11 4.000756631795862e-09 5745.385425762634 -3.242101410238644e-10 3.592179497356141e-09 -1107.9787590887631 7.567832844356659e-11 2.3265944579412508e-09 3074.320622285143 -1.7037457965519388e-10 1.9064516643610576e-09 -1118.9765915897528 -1.9999989757224703 44.68106132115811 -2234.0542102036693 +r_2638 MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 4.2085392619108064e-10 2.3193196831992067e-09 551.0985020836337 2.412168308508294e-10 2.253602986727512e-09 934.2644038471587 -1.8109036005902008e-10 4.500615512852204e-09 -2485.2871855715475 -4.529851616503472e-10 3.868011560479988e-09 -853.8936565577065 -2.808163381785132e-10 4.812961773884185e-09 -1713.918002457754 8.318555730927337e-10 5.495658804070544e-09 660.6505963094506 5.865006358860027e-10 4.900789863589544e-09 835.5983887700512 -4.45329888547726e-10 3.5861111473134502e-09 -805.2707081952633 1.7999992881537077 42.392426518172655 2355.13573795106 +r_2639 MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -3.934239389222377e-10 6.9528638040397564e-09 -1767.2701419966277 5.960492564605756e-13 2.2960731407697704e-09 385215.33512249927 6.438881430549184e-10 5.822993394000462e-09 904.348597937112 8.435301296568392e-11 4.534268077744736e-09 5375.348097630305 3.157568443510566e-11 3.604506809989528e-09 11415.451080395453 -1.407503047489398e-10 2.910634278674277e-09 -2067.941724080851 -2.8036858876077163e-10 3.04004093939453e-09 -1084.3015449168197 5.179177713169585e-10 5.194378075483043e-09 1002.9348987726 -2.999997844980954 64.74437343226337 -2158.1473313583137 +r_2640 MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -4.6167762579297956e-10 3.679213818054534e-09 -796.9227037448695 -5.937882396221983e-10 2.0949391457499224e-09 -352.8091339570554 -1.0942958300823711e-09 5.753365953971499e-09 -525.7596525373239 -4.488945541265001e-10 5.39214730723797e-09 -1201.205774868555 8.111756068175815e-11 2.3678241123499967e-09 2919.003101732171 -6.970993515700964e-09 1.6544183686474773e-08 -237.32892089501783 -6.28864033593445e-11 3.06438824956238e-09 -4872.8947528639865 -6.228760602317278e-11 5.5795695113634295e-09 -8957.752380606293 -1.8000004054377612 42.39243591479085 -2355.134798121392 +r_2641 MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 4.3918545669095645e-10 6.828265349838767e-09 1554.7567083132358 -2.9588160992772556e-10 2.667967318063831e-09 -901.7009602981174 4.5427043713001406e-10 3.6810110665691513e-09 810.3127048779602 2.4974349835611004e-10 3.361938172925993e-09 1346.1564345239508 -2.8533094033447155e-10 2.33877246539411e-09 -819.6701215271456 9.63119594208148e-10 7.524440329181708e-09 781.2571122455573 -8.250042309737479e-11 6.493573135119205e-09 -7870.957373703256 2.1015459784840346e-10 4.6430553633898224e-09 2209.352263013119 -8.144663438198656e-11 2.3022478124150447e-09 -2826.69484121032 +r_2642 MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 2.852826245660841e-10 7.2561265482257815e-09 2543.487027736924 -6.57895833124678e-10 2.639024436260204e-09 -401.13104588702913 3.889396487215232e-10 3.727611555417551e-09 958.4035897781362 1.1528392855530172e-10 3.434973707053032e-09 2979.5772490571176 -2.639991745244677e-10 2.725798350164556e-09 -1032.5026034927723 2.266695380627407e-09 1.3881081199183136e-08 612.3928833940156 -1.81945980038718e-10 2.948622910465746e-09 -1620.6034944208611 -1.7791629719209506e-10 2.2800819900066222e-09 -1281.5475737699464 -3.8699977466949446e-11 2.6729907486203063e-09 -6906.95686038343 +r_2643 MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -7.099779385111702e-11 3.490624677435964e-09 -4916.525553957118 1.443400148537791e-09 5.107638648966942e-09 353.8615853781876 -1.5624979449941066e-10 3.437077756837333e-09 -2199.732657472581 2.057227567973612e-10 3.4135844628034633e-09 1659.3130074403366 -1.0045897578701508e-11 2.972951190226007e-09 -29593.684057948347 2.472594146205968e-09 1.2431196486594513e-08 502.7592783744699 -1.330416882950506e-10 6.178706898331535e-09 -4644.1885829266 3.8814483121205757e-11 2.4359432503020268e-09 6275.861622825997 1.8000004056048522 42.39243591472599 2355.1347978991653 +r_2644 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane -5.702636606922832e-10 2.968171120338924e-09 -520.4910158111165 3.863838420580119e-10 4.278255443777098e-09 1107.255267453642 5.855111323129452e-11 2.4526740850173587e-09 4188.945264505148 1.2821196862987724e-10 3.855678186238825e-09 3007.2685315123817 4.1362222766902895e-12 2.391331382687853e-09 57814.382852783776 1.8473503888651704e-10 2.165667184781517e-09 1172.3099190251012 0.9999995276281106 31.610105381826315 3161.0120313558573 4.1207852880902603e-10 2.895580867093695e-09 702.6769570990255 -2.0194779080145588e-10 4.147936912789186e-09 -2053.9649858646944 +r_2645 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane -3.854069909431209e-10 2.519499679971673e-09 -653.7244365511536 1.9999999095183445 44.68107333012949 2234.0537675769165 8.528156374824613e-12 3.159312567017649e-09 37045.66881939501 2.3711883507067967e-10 5.304843383332772e-09 2237.208774137035 1.0951274683982708e-10 2.3138646132055244e-09 2112.8724098115954 -4.474032189528727e-11 2.3033167792262755e-09 -5148.190003230387 1.929767489371388e-10 2.964106509027128e-09 1535.991525068479 -1.3235071046515356e-10 7.113286062265709e-09 -5374.573387075664 -2.3851696307872247e-10 4.014210809808139e-09 -1682.9875569408655 +r_2646 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane -1.7951612945018516e-10 2.1258955000613248e-09 -1184.2364842493164 -2.1999993058260925 46.85719749717892 -2129.8732855547064 -3.650091396619127e-10 3.12928933757135e-09 -857.3180771500226 1.1056497533986623e-09 6.747646526807731e-09 610.2878878294058 3.9930058476708127e-10 2.7890946590569943e-09 698.4950098893343 2.389061252386132e-10 2.070444222656518e-09 866.6350519847963 -5.999997234782528 77.23462658367815 -1287.244369646406 3.782531648162708e-10 4.0558881613504276e-09 1072.2681364266964 -1.2130085702927735e-09 8.129015756984508e-09 -670.1532005682759 +r_2647 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -4.4592146765205293e-10 2.182612593043497e-09 -489.461205923946 0.1999993968466918 42.43016456480528 21215.14626233089 1.1806320005664728e-10 2.7105926893345473e-09 2295.8827882303644 7.844518918423894e-11 8.580771402040502e-09 10938.55657851423 2.0429508495388404e-10 2.97067418580329e-09 1454.109474280239 1.4479002746984903e-10 2.5893894466169117e-09 1788.375547588127 4.999997706329324 70.5407019830639 1410.8146868501335 -1.932049466099243e-09 9.920427064411807e-09 -513.4665151426423 2.8011485864526243e-10 9.132965444774589e-09 3260.435911520344 +r_2648 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane 2.5728452297852843e-10 2.2431803601500006e-09 871.867586196471 -5.56653606096925e-10 6.803343265734514e-09 -1222.1861479416896 -1.7489010024647758e-10 2.421273011044248e-09 -1384.4540129097525 2.953989060010933e-10 3.624016599725989e-09 1226.8212664648718 1.1248878449452335e-10 2.375071380634376e-09 2111.385051680427 -5.161455466028324e-11 2.414431159727951e-09 -4677.810698201812 1.6454055170093342e-09 1.0151519118965633e-08 616.9615340427987 -1.4376990152589008e-10 3.896164714460709e-09 -2710.000266473777 -4.29560815591932e-10 5.808115899127836e-09 -1352.1056130607 +r_2649 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 3.6902296067493646e-10 2.069474354741585e-09 560.7982633266377 -5.500368269497493e-10 6.958314171353124e-09 -1265.0633249305731 1.412147620739873e-09 4.9007719421927745e-09 347.0438833884159 -1.6483193518663043e-09 1.4208903092615374e-08 -862.0236774219383 -2.717108549718154e-10 2.6380657624155063e-09 -970.9092272699788 2.864055452955332e-10 2.065332586614917e-09 721.1217172781214 -4.754958992678103e-10 4.623324772523505e-09 -972.316434199055 1.4305570821693904e-09 8.756678187781062e-09 612.11665699504 1.929974591626447e-09 1.1293741052818892e-08 585.1756340119131 +r_2650 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 2.5494675642904085e-10 2.220924523040346e-09 871.1326843879633 3.684647287994048e-11 4.476677045641338e-09 12149.540229340317 5.4681324376574446e-11 2.3300736518895224e-09 4261.187303809578 1.5082744975872548e-10 4.301100265916549e-09 2851.669422772114 -1.4740593995194354e-10 2.4143949872083288e-09 -1637.9224527827414 -3.203142555349328e-11 1.8516000949683647e-09 -5780.573492978469 -4.690053026197316e-10 4.351394127765305e-09 -927.7920960508634 9.402510029978124e-11 4.663262922938247e-09 4959.593670275614 -7.119962113167643e-11 5.652605627803694e-09 -7939.095093427219 +r_2651 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 1.0753938025302112e-09 3.50252533821449e-09 325.6969986226132 4.687002080125724e-10 5.3818788139039805e-09 1148.256118068464 -5.265423689334129e-10 2.5230563385703267e-09 -479.1744192743955 -4.960090880785332e-11 1.4294066125266156e-08 -28818.15367665799 8.853123820321241e-11 2.746175935563908e-09 3101.928755656172 1.9328630937329208e-10 2.9048524400856724e-09 1502.875423253883 -3.7625116486550636e-10 5.380681302931657e-09 -1430.0769819157954 3.212243966670962e-10 4.272172706290272e-09 1329.9652052013278 3.606167969350327e-10 5.529231981970225e-09 1533.2707818838371 +r_2652 MLCL (2-16:1, 3-16:0, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 5.276693362103478e-13 2.257322395995081e-09 427791.08829913737 2.413394589114541e-10 2.4593172101030956e-09 1019.0282273755336 3.8031264698793664e-10 3.205268509748445e-09 842.7982963843205 -8.034944414996945e-10 6.100589535027808e-09 -759.2572169685789 9.993909828256401e-11 5.934440880677843e-09 5938.057259531231 3.5358944107292915e-10 3.2470676880097587e-09 918.3157953350872 1.475106762681681e-10 2.190625418253697e-09 1485.0622840825663 3.7766217769069636e-10 5.546051294830608e-09 1468.5217695728056 -3.03075144221913e-10 1.949524217760998e-09 -643.2478066672295 +r_2653 MLCL (2-16:1, 3-16:0, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane -1.7243433452026168e-10 2.357899016467545e-09 -1367.4185150118594 9.044568090628827e-11 2.170023976213827e-09 2399.2566084633845 3.792558416757208e-10 3.979556534650349e-09 1049.3065886782126 2.8892272600177183e-10 2.6344574931723743e-09 911.8207936180896 2.7806013084392428e-11 3.464115856516734e-09 12458.15373100414 -8.12259588659691e-10 6.7489272703453324e-09 -830.8830532221517 2.317542007423156e-10 2.7998533013003997e-09 1208.1132908626407 -1.2998132841656786e-10 1.7698278691743415e-09 -1361.6016167355567 6.78595504493062e-10 6.317711714914262e-09 930.998167993147 +r_2654 MLCL (2-16:1, 3-16:0, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 1.246669491096815e-10 2.1796608426831075e-09 1748.3870891598144 2.1828866522833207e-10 2.3084389851807368e-09 1057.5166524409717 -1.989848893907861e-09 7.260542379287817e-09 -364.8790821009956 1.9007391836175063e-10 2.839429080355884e-09 1493.8551826725925 1.2536199745305776e-10 4.303972779042249e-09 3433.2356427663703 3.67627698064808e-10 6.503109373112869e-09 1768.9389040448348 7.215719924046124e-11 1.923438277814521e-09 2665.622138970129 -9.132970231679308e-11 2.0697790884022954e-09 -2266.2715807644963 -1.68190683826474e-10 3.7927262435642205e-09 -2255.015650853325 +r_2655 MLCL (2-16:1, 3-16:0, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 6.915161376357976e-12 3.452526180227353e-09 49926.90686917422 4.343096423090447e-10 3.335605028085961e-09 768.0246310793215 8.633294573076216e-10 5.031226312554388e-09 582.7701429584905 3.46703868771971e-10 3.340941059791309e-09 963.6295872973556 -3.0266672423475225e-10 4.200221766329664e-09 -1387.7382050997842 1.2256564543342867e-10 5.8086618858846234e-09 4739.225143671754 1.8927938321385848e-10 2.896234285050367e-09 1530.1372161478562 1.1199863624972514e-11 4.040118964798718e-09 36072.92999345456 -2.1691518489078108e-10 5.031954455474491e-09 -2319.779713904368 +r_2656 MLCL (2-16:1, 3-16:0, 4-18:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -9.303425642665939e-11 3.4354559365870013e-09 -3692.678448282364 -4.716373467882803e-10 2.364276866077943e-09 -501.2912743611193 -2.622560032468809e-10 1.9225568381004103e-09 -733.0840149693604 1.2457252370444684e-10 2.8447221678767126e-09 2283.5871693712543 -9.328282996220054e-11 3.693221155466779e-09 -3959.165000636583 -7.253213195404614e-10 6.395400200093228e-09 -881.7333818541462 -1.4302932238502254e-11 2.3733161099278315e-09 -16593.213687603653 -3.775303226473569e-10 2.405645320520664e-09 -637.2058550559728 1.3139203757587482e-10 1.963140311841481e-09 1494.109040441533 +r_2657 MLCL (2-16:1, 3-16:0, 4-18:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 1.3020808015282308e-10 2.654376399198573e-09 2038.5650384240173 -4.378768117995068e-11 2.3341140173458794e-09 -5330.52665600985 -1.2394887211326782e-10 2.2258380597362703e-09 -1795.7711286813797 -2.0974307204818023e-10 2.0187098591675756e-09 -962.4679563689504 1.0243259441145224e-10 6.9273946395945235e-09 6762.881170195197 3.9010113150905836e-10 2.60434812615022e-09 667.6084522174082 -3.5664673391343735e-10 2.497330228218089e-09 -700.2251782359575 -1.8898119078873238e-10 2.577018106715958e-09 -1363.6373524584685 -2.8531025195672526e-10 2.9245509066454926e-09 -1025.042348316694 +r_2658 MLCL (2-16:1, 3-16:0, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -7.754654406159002e-11 2.8806762896801407e-09 -3714.770689706317 -2.9447657818637907e-10 2.6060371854863553e-09 -884.9726526762856 5.831173212811071e-10 3.241869869270435e-09 555.954994125034 -1.9263587200302928e-10 2.567281287737318e-09 -1332.7119508130584 -4.702376827340346e-10 4.2132757708266844e-09 -895.9885448418438 1.0130482296106642e-10 3.318078108990124e-09 3275.3407113354624 -1.353660856315949e-10 2.002994631408732e-09 -1479.687192004632 1.5887867161423769e-10 6.258142943934622e-09 3938.944655283616 -4.983389166957405e-10 3.812195018489886e-09 -764.9803960258256 +r_2659 MLCL (2-16:1, 3-16:0, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -1.9689625219792358e-10 5.326580614765135e-09 -2705.27272881292 6.24490498289332e-10 2.922371465520274e-09 467.9609175040344 -5.20847557628108e-10 1.6508350583692767e-09 -316.951675051915 -1.2479844170377738e-10 3.139527046275548e-09 -2515.678083326997 -8.795123664949062e-11 3.6021617041280263e-09 -4095.635082976277 -3.3650701519615833e-10 6.033494038835841e-09 -1792.9771940471333 2.61649533337266e-10 3.6845081691762725e-09 1408.1844986235635 -1.1459424331280087e-10 3.959380462483634e-09 -3455.130334667821 -6.185091867989871e-11 2.924560833332389e-09 -4728.403224644196 +r_2660 MLCL (2-16:1, 3-16:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 2.4754349265899756e-10 2.1091346746839086e-09 852.025901399613 5.828017797589056e-10 3.5818981910313476e-09 614.5997344951681 1.0030293556261399e-09 7.588135301762252e-09 756.5217567361593 4.967724602368112e-10 2.270025942423567e-09 456.95486850085183 6.999996249809425 83.38095127195727 1191.1570848945428 1.1224902474810355e-09 4.4806224086547164e-09 399.1680478925867 1.7999990898241904 42.39241755139299 2355.135499292588 6.804047262639042e-10 2.909728771803729e-09 427.6467607420986 4.098974043827739e-10 2.980132126810432e-09 727.0434247559908 +r_2661 MLCL (2-16:1, 3-16:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 2.82992440078257e-10 3.161512621681534e-09 1117.1721127275584 4.006240387423001e-10 3.547936486168841e-09 885.602495872954 1.7462503193988547e-10 2.874402911232693e-09 1646.0428836011347 6.271726581861575e-10 3.227863232996654e-09 514.6689975822508 5.34580945598476e-10 5.0856669219807115e-09 951.337110657243 8.343330071909866e-11 3.160055190120704e-09 3787.522683250788 1.5437703500269228e-10 3.668234457809405e-09 2376.1529412360023 2.5203770177586003e-10 3.587292469850128e-09 1423.3158152824087 2.9603974053163086e-10 2.4620597741022915e-09 831.6652925316383 +r_2662 MLCL (2-16:1, 3-16:1, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 5.306753731863443e-10 3.1223650991812413e-09 588.3757296732206 7.38097149404357e-10 3.895859382762764e-09 527.824743112301 2.959933502491155e-10 6.027530538280971e-09 2036.373632450881 7.716505633653364e-10 3.128290864023639e-09 405.40252447694456 -6.999996248585191 83.38095127174066 -1191.1570850997707 5.333841621238665e-10 3.471501575218341e-09 650.8445172791169 -1.599998818156002 39.97195509776479 -2498.2490389481945 2.0540758383104463e-10 3.045723499772424e-09 1482.7707151638792 -2.4808466360593156e-10 6.798762602781477e-09 -2740.500966065733 +r_2663 MLCL (2-16:1, 3-16:1, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 1.1878353156834428e-10 2.8659685294763223e-09 2412.765887354793 -2.5582897089901974e-12 6.443946883645276e-09 -251884.95505416457 5.644662474228313e-10 4.368751092815907e-09 773.961439282189 7.01874539424835e-10 2.902380141575917e-09 413.5183681052641 1.5442832485084203e-10 4.034980011225963e-09 2612.849692647535 2.2306248548987327e-10 3.6349579056629564e-09 1629.5693548290433 -0.2000002698200054 14.142135619925073 -7071.058270397632 1.3814721529402038e-10 3.461969842371977e-09 2506.000453938811 2.936918849413247e-10 3.003812492188431e-09 1022.7768100533486 +r_2664 MLCL (2-16:1, 3-16:1, 4-18:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -6.662542009182135e-10 4.360327200430537e-09 -654.4539898467057 -8.901287236961926e-10 5.171217725275841e-09 -580.9516744727377 -1.0787310379495344e-10 2.7386073025556637e-09 -2538.7304214044334 -2.0611037105330232e-10 2.774788179936978e-09 -1346.2632500037512 3.153477295225109e-10 2.8066458156975007e-09 890.0161798999571 -1.4977963355852774e-10 2.506785281633429e-09 -1673.6489615284572 -9.054551048461164e-12 3.4735855280759634e-09 -38362.86867769446 -2.6403146339627487e-10 1.954636141145765e-09 -740.3042485933298 -3.199999806806157 56.48357493053001 -1765.1118231442929 +r_2665 MLCL (2-16:1, 3-16:1, 4-18:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -3.1175844285159664e-10 7.572105563491269e-09 -2428.83736980164 4.249241339094377e-10 3.6604173221584237e-09 861.4284362908302 1.6094568478822316e-10 2.0875021086562953e-09 1297.0227262713436 -3.904964871484712e-11 3.254537014680234e-09 -8334.356701761628 -3.3763073377216905e-10 8.703272957209983e-09 -2577.749027753762 -7.151398583201409e-11 3.153671941931228e-09 -4409.867392008024 -4.696194389464153e-10 3.16986291349466e-09 -674.9854564381328 -1.599999198284734 39.9719646025453 -2498.249039461827 -1.843866935637916e-11 2.773903300470454e-09 -15043.945128886302 +r_2666 MLCL (2-16:1, 3-16:1, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -4.48260644722333e-10 2.303335566063698e-09 -513.8384538509862 5.994713069706568e-11 2.388297340271328e-09 3984.006094203657 1.1718352505895227e-10 2.4861016894827112e-09 2121.545403444736 -2.4974384282637565e-10 2.760823752037977e-09 -1105.4621890948192 2.2683715740704963e-10 3.290393813439443e-09 1450.553274010118 -1.1979204052874384e-09 6.890657359225223e-09 -575.2182973769299 5.31057176404733e-10 6.317034578137099e-09 1189.52061262095 1.599999198577145 39.97196460252346 2498.2490390038893 -1.880065249993688e-11 2.7233783279058206e-09 -14485.552179186145 +r_2667 MLCL (2-16:1, 3-16:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -3.135662973744922e-10 4.193481148205856e-09 -1337.3507240153372 6.423699477836297e-10 3.149239752836746e-09 490.2532821939404 -3.510878259464243e-10 5.437251871803488e-09 -1548.6871004844263 -2.0321018141936915e-10 2.925185029154842e-09 -1439.4874354834 -1.7363258246048067e-10 9.43546517872651e-09 -5434.155873868922 -4.957509802173144e-10 5.283700401633436e-09 -1065.7972676760628 -1.7862472859842939e-10 4.367335154436434e-09 -2444.9779091084 -1.1339367158300364e-11 2.839731707499058e-09 -25043.12337589658 3.199999806823703 56.48357493034586 1765.11182312886 +r_2668 MLCL (2-18:1, 3-16:0, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 2.4262496308924507e-10 2.64521051989859e-09 1090.2466449528515 5.502653696910715e-10 2.149875484555878e-09 390.6979437508226 4.349380916831941e-10 4.640203071440816e-09 1066.865183843384 1.7459842571125607e-10 1.9575118663377224e-09 1121.1509258250574 -0.999999399176544 31.61010346243718 -3161.012245454019 4.144903871763321e-10 2.8746205714945516e-09 693.5313002256994 1.9279307059002862e-10 3.368330743504357e-09 1747.1223074542231 1.0198619431940835e-09 2.5929986214526753e-09 254.2499638070344 6.600000644158671 80.97992196371189 1226.968394849827 +r_2669 MLCL (2-18:1, 3-16:0, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 1.285678931558117e-10 2.379134376868548e-09 1850.4887328170416 7.71450481577581e-10 3.08080977711153e-09 399.3528879276107 2.0128446013444639e-10 3.112303222797649e-09 1546.2213132195152 2.90006057115567e-10 1.7795630370930564e-09 613.6296099442857 -4.999997453417585 70.54069846083053 -1410.8146877677857 -2.1097835414366416e-10 3.884061787647315e-09 -1840.9764373280168 1.8529887418695474e-10 2.7963662767848833e-09 1509.111314925491 2.076144197909752e-10 1.8144204022163646e-09 873.937563702517 -9.339782051438904e-11 2.2512986422427278e-09 -2410.4402328059555 +r_2670 MLCL (2-18:1, 3-16:0, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 3.876495589841026e-10 2.773137934995526e-09 715.3723951764516 7.337955393820814e-10 2.3781667554537156e-09 324.0911981362459 6.636142181561651e-10 7.516269394936373e-09 1132.6263345924278 2.6593311301401023e-10 2.560801333193106e-09 962.949406401374 4.799997780371326 69.12243605851576 1440.051417131457 3.85371687715886e-10 5.7240739905359455e-09 1485.338485674121 7.691648506921519e-11 2.4547120973898878e-09 3191.3992106906016 4.5410709717257766e-10 2.5204816919548522e-09 555.0412463597711 -3.0785847262427885e-10 1.536551752348006e-09 -499.1097822483081 +r_2671 MLCL (2-18:1, 3-16:0, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 1.4529897944184694e-10 3.1771354957702147e-09 2186.6192783837137 4.97633051573232e-10 2.5676200214495103e-09 515.9665366542997 7.46682056795027e-10 4.8523560887305405e-09 649.8557243438042 1.0482777312298354e-09 3.586317680181133e-09 342.11522131388574 1.1999990720593667 34.62366119393296 2885.3073306560063 2.7227681008169166e-10 2.9092199510148633e-09 1068.478784565606 -6.540185857390696e-10 5.541048232503379e-09 -847.2310043363293 5.495137989191313e-10 2.478993064500737e-09 451.1248069433021 -6.600000643463746 80.979921963742 -1226.9683949794728 +r_2672 MLCL (2-18:1, 3-16:0, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -2.611763113584315e-10 1.6848518244968455e-09 -645.1013170886694 -5.49751741915057e-10 3.184918772106681e-09 -579.3376408434895 -3.3376954829799724e-10 2.726067259512425e-09 -816.7513403824751 -2.5289534348566584e-10 1.3958064756454535e-09 -551.9304770135351 -4.270298894432176e-11 1.847033968684153e-09 -4325.303718417479 -1.0104407736051935e-09 5.258013021751168e-09 -520.3682550329877 -1.0501885993905096e-10 1.7811743893775167e-09 -1696.0519190660077 -3.2316943997225044e-10 4.052737975573483e-09 -1254.0597823610672 1.421999999999995e-10 9.796790873662635e-10 688.9445058834509 +r_2673 MLCL (2-18:1, 3-16:0, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -3.167925209740727e-10 2.0641799701280077e-09 -651.587342965381 -2.997264072882677e-10 4.121496344193332e-09 -1375.086159902288 -5.663350805694466e-10 6.499808301069762e-09 -1147.696571177304 -4.2772474892241327e-10 1.7894553957193791e-09 -418.3661105015871 -3.965522207659414e-10 1.0896450512315643e-09 -274.7797122726769 3.5901129665011987e-10 3.4499017379607518e-09 960.94517641959 -3.2488397951475576e-10 1.9619395013380496e-09 -603.8892728008278 -0.9999985705421436 31.610074850481613 -3161.012003581604 -2.415080825434035e-10 1.6130974181485475e-09 -667.9268872331195 +r_2674 MLCL (2-18:1, 3-16:0, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -5.024695365884123e-10 2.4180300216859557e-09 -481.2291782111826 -1.986850361520409e-09 7.00655719613159e-09 -352.6464464475281 -1.7081486512104288e-10 2.677221649353009e-09 -1567.323574242719 -3.4849425096198723e-10 1.661236922490071e-09 -476.689907481795 -2.1890224394938207e-10 1.894357500696293e-09 -865.3897130146985 -1.688331299565444e-10 3.590985989459648e-09 -2126.9439181657804 1.332085809539428e-10 1.845660572354953e-09 1385.5418015398686 0.9999985679037844 31.610074850309683 3161.012011904308 6.110187061679036e-11 1.4133605784540808e-09 2313.1216183514016 +r_2675 MLCL (2-18:1, 3-16:0, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -1.316692533996489e-10 4.008812187222683e-09 -3044.6076693812047 -1.1906532932508668e-10 4.273375517410795e-09 -3589.101497164724 -1.3869434743687227e-09 5.579329458243964e-09 -402.2751872266053 -8.504268644386358e-10 3.6994778296183515e-09 -435.0142245400922 6.381889557093397e-10 1.939195966893422e-09 303.8592174848949 -2.1525259180245935e-10 3.964372562700922e-09 -1841.730466288224 3.1296079932798955e-10 1.924470829000177e-09 614.9239243804753 -1.571293860778626e-11 2.70326204657435e-09 -17204.051476627028 1.6034074057063176e-10 1.701063568426819e-09 1060.9053958295042 +r_2676 MLCL (2-18:1, 3-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 1.9820413248511727e-10 2.693658354089179e-09 1359.032387627659 6.501781825231186e-10 3.354348541048304e-09 515.9121962584512 8.81918353776212e-12 1.953831371677165e-09 22154.33393931784 -1.7492399554784326e-10 3.356369778606353e-09 -1918.7589261808032 2.053958644255423e-10 2.425887827918241e-09 1181.0791978227223 5.468311042283976e-10 6.221844267908003e-09 1137.7999934161198 1.7270852673286375e-10 2.5117578410421672e-09 1454.3334301769703 -3.3999971446346 58.21608140166101 -1712.239126245429 -3.5999984872684245 59.89786757274148 -1663.830353945239 +r_2677 MLCL (2-18:1, 3-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane -7.69484392114865e-10 5.6325884221111914e-09 -731.9951489373916 6.694517527113409e-11 3.262909942651365e-09 4874.003136800047 -2.9098997779238813e-10 8.951940524679607e-09 -3076.374173637872 5.828759970386467e-10 9.577480125341114e-09 1643.1419674168003 3.091683832951482e-10 2.384290443196095e-09 771.1947831741664 -9.411427375212755e-10 4.406356543150347e-09 -468.1921633646711 2.5504472494012116e-10 2.6499566260640247e-09 1039.016441797091 -0.4000004885386116 19.99798966402292 -4999.491309894371 0.9999994010954972 42.41883865383488 4241.886405868357 +r_2678 MLCL (2-18:1, 3-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 4.409192952834698e-10 3.009686038421372e-09 682.593406688275 3.177047158680937e-10 3.2060664116528394e-09 1009.134032805465 -6.206351740195248e-10 3.476247965981149e-09 -560.1113361763458 -1.774130783273697e-10 8.942028404690068e-09 -5040.230680282702 2.917827782261703e-10 2.30890673330211e-09 791.3101476854133 5.763367564356391e-10 6.8150105296674284e-09 1182.470223106181 1.0376704551204015e-10 2.3903373342034462e-09 2303.561137746852 3.79999763525634 61.53302002762996 1619.2910084134585 5.0831435034425444e-12 2.680092232219164e-09 52725.09482378531 +r_2679 MLCL (2-18:1, 3-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 7.783460599669879e-11 2.4948351214915512e-09 3205.3032061309145 -9.171896091375055e-10 5.174817248475768e-09 -564.2036495967275 8.131375066986723e-10 8.664289413142519e-09 1065.5380352973043 -1.4506374437823276e-10 3.624156461393445e-09 -2498.3199468117823 3.1870788311143217e-10 2.9289778318750427e-09 919.016437020782 -1.535685855102824e-10 2.570944300421876e-09 -1674.1342585653597 1.1452640278868944e-10 2.5635735288462484e-09 2238.412686004162 -2.052270719997269e-09 9.916705692299528e-09 -483.20650856007535 2.5999990863623927 50.92894004535063 1958.806074682292 +r_2680 MLCL (2-18:1, 3-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -1.2652089776631735e-10 2.5057136618482224e-09 -1980.474139913429 -1.270152611932489e-09 3.937763252311085e-09 -310.0228441305118 -4.450981932984671e-11 3.0039641384005444e-09 -6748.991983407564 1.1095041284146076e-10 1.419156805207565e-09 1279.0910541589658 -1.0831367850800516e-10 2.1129922263244548e-09 -1950.808296265452 -1.679067911122019e-10 1.801288287150409e-09 -1072.7906091342772 -8.324000200054731e-11 1.964418013016916e-09 -2359.944697026797 2.400082307641461 48.93582989935298 2038.922987913768 -6.01322683668248e-10 4.179821373668659e-09 -695.104556537016 +r_2681 MLCL (2-18:1, 3-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 1.2427955163437774e-11 1.802825215431421e-09 14506.209522989067 3.769527581098285e-10 1.8970720285810714e-09 503.2651937854616 9.636955182205064e-11 3.286656455725348e-09 3410.4718695737647 -1.5284606603136812e-11 2.123367118677079e-09 -13892.193458491152 -4.5678244872792407e-10 2.211209534964427e-09 -484.0837341982685 3.980648194685652e-10 1.587669193563047e-09 398.8469002818834 -3.3872415669098547e-10 2.225829379199082e-09 -657.1215353942657 -2.4000823079742486 48.9358298992922 -2038.9229876285249 1.1969029083218656e-10 2.201051599300194e-09 1838.9558451204784 +r_2682 MLCL (2-18:1, 3-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -2.725899031190803e-10 2.195510701148801e-09 -805.4262744242942 2.2329863962801927e-10 2.593754857861763e-09 1161.563215155522 9.587861953357859e-11 5.205506041305816e-09 5429.26678192602 -7.404599998555996e-11 1.999002856724953e-09 -2699.677034701115 -3.2739190629813936e-10 2.302956006641367e-09 -703.4248441512112 -7.888234530714609e-11 1.6387723643438063e-09 -2077.489402683045 -3.809214166801684e-11 2.033164785672303e-09 -5337.491400173494 6.551476665682023e-11 2.434459577366174e-09 3715.894448832233 2.0139212620285319e-10 2.0830878003071287e-09 1034.3442117538043 +r_2683 MLCL (2-18:1, 3-16:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -5.1559822850588165e-11 2.387836977832428e-09 -4631.197017010676 6.716850819281147e-10 2.316624858190063e-09 344.8974706331194 -1.3111679477857282e-11 7.104569834877303e-09 -54185.048123509616 -1.0345465936900547e-10 1.9344444608010593e-09 -1869.8475956517525 -2.1260020302074622e-10 2.625553588953759e-09 -1234.972286784481 -2.1494490928082277e-10 1.7090985221292562e-09 -795.1332868722848 -2.1522961230221798e-10 2.8840713971077526e-09 -1339.9974874544864 2.530430675045983e-10 3.453997997291048e-09 1364.9842421501164 2.5087051536348265e-10 2.624758584168357e-09 1046.2602910371445 +r_2684 MLCL (2-18:1, 3-18:0, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 1.3384557556457348e-10 2.6900681344050727e-09 2009.829703416124 7.179218842348385e-10 8.054418306572928e-09 1121.907338868397 -2.653619067103875e-11 3.50024626911049e-09 -13190.462461255274 4.010561856320286e-09 1.6625319954738412e-08 414.5384250473135 -4.88309800699289e-10 9.315062599497358e-09 -1907.6132787336296 2.8162754783227103e-10 1.9529849079173683e-09 693.4637335551093 -4.362933599396063e-11 2.990570925091969e-09 -6854.495620804169 2.5128928304434686e-10 6.1968826582909916e-09 2466.035392841398 -4.19999424536349 64.67754773960412 -1539.943722803996 +r_2685 MLCL (2-18:1, 3-18:0, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane -8.642258598649581e-12 3.017663959511597e-09 -34917.538338683014 -5.29765137062052e-10 2.7229307923355873e-09 -513.9882944046292 -1.6568594325185932e-10 3.7514930502817724e-09 -2264.219267279135 -4.32040062014217e-09 1.5923888606993635e-08 -368.5743524050701 2.4847034377705836e-09 1.0479510558230608e-08 421.7610198033701 -3.017477858490545e-10 2.5922693048429634e-09 -859.0847808705092 2.558914890389149e-09 6.629391443791788e-09 259.0704156941936 -3.1459230763882886e-10 1.7134027288603871e-09 -544.6422837609485 4.199994246003655 64.67754773938158 1539.9437225639783 +r_2686 MLCL (2-18:1, 3-18:0, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 3.540161241162136e-10 2.810024636296584e-09 793.7561158581949 9.67236346524294e-11 8.392207137716739e-09 8676.480332726984 -8.47209751673557e-10 5.496297764904216e-09 -648.7528919546744 1.291022911310054e-11 3.455114550909337e-09 26762.61219410344 7.735997476666854e-11 3.3716403484485676e-09 4358.378293966661 4.806439739917064e-10 2.417488918288943e-09 502.9687355095515 -9.035804995146912e-11 2.223023144077566e-09 -2460.2380698471707 -2.48079346668414e-10 2.368188552684461e-09 -954.6093153211228 -1.5209845607081978e-10 2.429957773710988e-09 -1597.6215909644447 +r_2687 MLCL (2-18:1, 3-18:0, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 2.4674194257903017e-10 4.192555023733005e-09 1699.165930166149 -4.4825871422193885e-10 3.211792720554726e-09 -716.5042460199726 2.8028254228742233e-09 8.387046463220283e-09 299.2354213277968 1.0061911041804767e-10 3.1382303787053886e-09 3118.9208150090094 2.644593465721874e-10 9.194476187900858e-09 3476.706838716744 2.4802397691700256e-10 1.8245478814739198e-09 735.6336690321177 6.559482484024426e-11 4.185953979618008e-09 6381.53084456414 -3.8782552056254955e-10 3.042386017685984e-09 -784.4728766876754 -4.00719865259993e-11 4.196437421149376e-09 -10472.247035785624 +r_2688 MLCL (2-18:1, 3-18:0, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -3.580728436436019e-10 3.1301085728085992e-09 -874.154136057318 -5.58079457658306e-10 1.6550187068459744e-09 -296.55610579009857 6.199997958162182 78.503420978114 1266.1846263153311 -6.132112315089196e-11 1.1556506940301081e-09 -1884.588270156788 1.973887080503889e-10 3.5796003093149326e-09 1813.477753955986 -1.7599116778214496e-11 3.6539486362380363e-09 -20762.113703121555 -3.5882891726962433e-10 3.577623720537784e-09 -997.027705503889 -3.0773071331400223e-10 1.104303791891614e-09 -358.85394083651465 5.972391801676551e-12 1.440038815911796e-09 24111.59320638597 +r_2689 MLCL (2-18:1, 3-18:0, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -2.7368552766727794e-10 2.7150234025562315e-09 -992.0230074631168 3.0999579936103406e-11 1.682540180375035e-09 5427.622515669894 -6.199997960921522 78.503420978493 -1266.1846257579225 -1.9082150956165047e-10 1.4019670999974504e-09 -734.7007699593237 -5.629544372309531e-11 4.147492659257771e-09 -7367.368271681737 7.769124766750256e-10 6.772082313098215e-09 871.6660520218297 -5.509585316065815e-10 2.6733380388098717e-09 -485.21583484958165 -1.8233106596894287e-10 1.4105268270684802e-09 -773.6075142064603 -2.7046695467043395e-10 2.1228594502499447e-09 -784.8868091248578 +r_2690 MLCL (2-18:1, 3-18:0, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -5.034151792218281e-10 3.04567606964717e-09 -605.0028277564319 -3.8282116227279705e-10 1.247718925508668e-09 -325.9273646475029 4.5664886854954335e-10 1.2355936126017956e-08 2705.784898857669 -1.4980507696015486e-10 1.5945465710496354e-09 -1064.4142397615492 -3.463230911130363e-09 7.856050816404471e-09 -226.8416694698632 -2.04625492313316e-09 8.487062607592398e-09 -414.7607666887017 -1.817311634497229e-09 7.428814495474057e-09 -408.7804399892749 -1.8099116467200904e-10 1.6720164514626082e-09 -923.8110901670948 3.9616919499501065e-11 1.2422368876334727e-09 3135.622111277777 +r_2691 MLCL (2-18:1, 3-18:0, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -1.3266419467318356e-10 5.4840713436011526e-09 -4133.799143854216 8.492409253253587e-10 2.328385425421991e-09 274.17254114666537 -4.5551224706224014e-10 3.2101042144068e-09 -704.7240189720252 3.5028090433222594e-10 2.335498943240645e-09 666.7502893693368 1.2155378984553096e-10 3.8271497726659464e-09 3148.523610435709 8.148628250254753e-11 4.225470994942014e-09 5185.499773915827 -7.039766277891072e-10 4.928130817713174e-09 -700.0418228642545 5.538314622735825e-10 2.0635092641616607e-09 372.5879450204159 9.876952105894028e-11 1.914598087668937e-09 1938.4503105228268 +r_2692 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 7.002264471921322e-11 3.6563528095519556e-09 5221.671966566986 3.252865774730065e-10 3.088198462168748e-09 949.3777721046664 1.6615725489556183e-10 4.9786352356930285e-09 2996.3393646713475 5.443732647704337e-10 2.8758532377300916e-09 528.2870089042414 -0.5999997983435243 24.489988814857043 -4081.6661743002 9.45886293467309e-10 6.186945689787441e-09 654.0897920307233 6.479822220857527e-10 2.7216715910800353e-09 420.0225713476216 1.607963606762915e-10 3.366805655924061e-09 2093.83200077642 5.5150255227703297e-11 2.1628958044173554e-09 3921.823744037508 +r_2693 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 3.1425980047348185e-10 3.052155088709752e-09 971.220335566687 -1.7693925464763928e-10 2.544816777429578e-09 -1438.2431883175852 -5.131607257357522e-10 7.990724725683507e-09 -1557.1582790609475 8.454021837596212e-10 3.054441777268559e-09 361.30043616459926 0.5999997997137032 24.48998881495164 4081.666164994941 -3.6702131448196894e-10 3.5794390147853157e-09 -975.2673410364472 9.50414493604764e-10 3.689739634830056e-09 388.2242600105442 -1.1252522829393032e-10 3.286337632958231e-09 -2920.534072922648 -8.422734942422248e-11 3.169527510153617e-09 -3763.062154775715 +r_2694 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 4.97178645162004e-10 2.3923504158706103e-09 481.185271964179 4.3037253024092414e-10 3.515139025974537e-09 816.7665868466905 8.022020028908933e-12 4.783441038590964e-09 59628.88426297727 6.065851597242835e-10 3.051703998795173e-09 503.09572363792927 7.748416032799439e-11 4.238319491809512e-09 5469.917301637509 9.457629131008876e-11 3.874447583800142e-09 4096.63725457042 6.51142636728059e-10 2.73939644476416e-09 420.70604660899073 3.3386417415433336e-10 4.8511281839667774e-09 1453.0244810646489 4.1263640150595776e-10 3.590723692151303e-09 870.1907245813986 +r_2695 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 1.1621004655744923e-10 2.720812239273005e-09 2341.2883135951183 -1.100307691311512e-10 2.858934072275915e-09 -2598.304178777672 1.342223542536115e-09 6.879633721339461e-09 512.5549882950553 6.905600636113154e-10 2.98205039148625e-09 431.830705049968 -1.8998710761737328e-10 3.172007770838255e-09 -1669.5910636349895 -2.2946517142056687e-10 3.1763678440671476e-09 -1384.2483477570793 5.97233813489853e-10 3.2028268364707638e-09 536.2768758445691 -6.423472824561264e-11 2.868068186805301e-09 -4464.980650091247 4.2933296816758215e-10 3.6997882568764045e-09 861.7526561417618 +r_2696 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -2.1711485783591075e-09 7.893689959897521e-09 -363.57207602362007 1.7999994742749503 42.392422097502376 2355.135248835463 -1.7999995271327571 42.392426508314514 -2355.1354247210256 -5.415996572343256e-10 2.857014160410101e-09 -527.5140266889056 -2.560327100206161e-10 3.1975960041120627e-09 -1248.9013625855018 -2.78840225334213e-10 2.2628264316511296e-09 -811.5136289747815 -7.517426871571514e-10 3.6146157160975244e-09 -480.8315102827056 -1.0830932558727444e-09 7.06208010519002e-09 -652.0288134837914 1.660813270442854e-09 1.1345089998954454e-08 683.1044886779655 +r_2697 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 2.9471626992548165e-10 4.481054794970274e-09 1520.464002921623 -2.9999993839368333 54.695482227497806 -1823.183115315248 1.7999995259479478 42.392426508317634 2355.135426271414 -5.939929906445248e-10 2.879947796094348e-09 -484.8454176150124 -5.006405847440567e-10 2.4355682670866807e-09 -486.4903767903313 -7.064617685510381e-11 2.558581272336297e-09 -3621.683983811296 -8.120499462372586e-10 2.8261433257353484e-09 -348.0258004856302 2.4060590135141635e-10 2.011864900592674e-09 836.1660662903901 -2.4337529108929127e-09 1.0893672397791558e-08 -447.6079863750346 +r_2698 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 2.0966128192869688e-10 4.359043124599803e-09 2079.0882725224665 1.1999999088311069 34.62367389433169 2885.306377069465 1.5133800672135492e-10 4.110725048499661e-09 2716.2542559902813 -5.751002838985524e-10 2.3173527791442846e-09 -402.9475978407038 -4.659420704909419e-10 1.869063492993308e-09 -401.1364526547176 -3.6317284569850647e-10 3.462553409458832e-09 -953.4174843934568 -6.687687787530491e-10 3.0873248814065477e-09 -461.6430939199957 -2.2330705787676787e-10 7.371394271241083e-09 -3301.012668981108 1.2672180325550424e-10 3.7118168495044158e-09 2929.1067157720468 +r_2699 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 4.821147686423246e-10 5.023773212377427e-09 1042.02848349259 3.938263250546176e-10 2.163873395687847e-09 549.4486422124654 -3.8113807966102714e-10 2.8905671825200886e-09 -758.4041943777626 -7.846132896189319e-10 2.749865283589161e-09 -350.47396213804967 -2.2723534838838302e-10 2.6650783276887088e-09 -1172.8273556866015 2.1107342443070383e-10 5.2501434699893995e-09 2487.3540968740185 -8.339845677127577e-10 3.2700293911220086e-09 -392.09711039260833 3.30080394884187e-10 3.5095314890591662e-09 1063.2353643089075 -3.299880522492423e-11 2.80707422936269e-09 -8506.593527339248 +r_2700 MLCL (2-18:1, 3-16:0, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 3.673375251724837e-10 2.939087178332317e-09 800.1053464255431 3.186375514191761e-10 3.4516437535432404e-09 1083.2507776217856 7.369425464330437e-10 3.984830683352186e-09 540.7247420629466 2.8509510453078887e-10 2.744926405760984e-09 962.8107821348246 -1.0181578155361065e-11 3.1013156249139116e-09 -30460.067954012884 1.480319804685895e-09 6.500184492424439e-09 439.10677083751466 5.362019335900384e-10 3.552532907539006e-09 662.5363850804669 1.393840944952274e-09 7.583718525258527e-09 544.0877994524833 9.34273582729224e-10 5.1583651071749484e-09 552.1257587211444 +r_2701 MLCL (2-18:1, 3-16:0, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 3.8730211223588366e-10 3.39659757889873e-09 876.9891698473506 0.9999994039743972 31.61009713411737 3161.01159745558 5.240513448985525e-10 2.818377034022643e-09 537.8055149478213 4.671004607654255e-10 2.662443027960945e-09 569.9936633755545 4.37953369257259e-10 3.731407174475058e-09 852.0101536844633 -5.732888558083861e-10 3.101470842474873e-09 -540.9961856142373 1.1133463592397323e-09 3.873183131121279e-09 347.8866301557899 2.4884787316252567e-10 3.3528104513152514e-09 1347.3333762935113 7.1728203197879e-10 3.2392654563226087e-09 451.6027604074144 +r_2702 MLCL (2-18:1, 3-16:0, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 5.556860101123526e-10 2.853127176626162e-09 513.4423261887222 0.9999993995780224 31.610103478831903 3161.012245824414 2.5263478538222336e-10 3.4465768504542836e-09 1364.2526880214812 3.2622388747207137e-10 3.045643166090341e-09 933.6051966308212 3.935685278231278e-10 8.793602252408481e-09 2234.325569945059 -1.3967860555512832e-10 2.83690218535173e-09 -2031.0212677717927 4.91003621475263e-10 3.1899042499146987e-09 649.6702082013882 3.9842253411573677e-10 3.757819053344963e-09 943.174326644226 5.475124139948437e-10 2.844248308260074e-09 519.4856291033539 +r_2703 MLCL (2-18:1, 3-16:0, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 4.883761854886084e-10 3.6220868540095075e-09 741.659188476952 -1.9999988028772848 44.681052864665176 -2234.053980451642 1.485938782490237e-09 4.972480333762994e-09 334.63561166562823 7.490257693014327e-10 3.2747285378334875e-09 437.1983811568476 -4.3878679995188887e-11 8.597114494285166e-09 -19592.919602932 -2.811259959969497e-10 3.262338563394062e-09 -1160.454248218816 4.715813806737374e-10 2.787754941509385e-09 591.1503413316668 3.220085313611945e-10 3.488455698955502e-09 1083.342632013227 6.85034007335963e-10 3.633856774555894e-09 530.4637048148372 +r_2704 MLCL (2-18:1, 3-16:0, 4-18:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -1.4856673703764652e-10 3.7415147407003505e-09 -2518.406754637316 -1.6197567989415755e-09 4.3841116750783714e-09 -270.6648107878388 -8.3080550622791e-10 3.598364236169564e-09 -433.1175238001426 -5.1550183570583964e-09 1.5831288766276932e-08 -307.10441107547723 -2.660822083417185e-11 2.667216901550146e-09 -10024.033242105192 -2.5205869017066816e-10 2.463140890386825e-09 -977.2092716656746 -1.230790658687969e-10 3.338228450962913e-09 -2712.263395402665 -5.273885745275788e-10 2.8376076214354717e-09 -538.0487478283594 -7.775739720415063e-10 7.962362535604574e-09 -1024.0006509862378 +r_2705 MLCL (2-18:1, 3-16:0, 4-18:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 1.04117221714449e-10 3.127490598045677e-09 3003.816800474283 1.6532818977312068e-10 2.576262256014159e-09 1558.2716169272492 -3.338843761247345e-10 2.352089620068408e-09 -704.4623193718119 1.0312007438518448e-09 1.3037683952411088e-08 1264.3206504789182 -2.9310797411030036e-10 6.106444735800591e-09 -2083.34309373059 4.659298595778649e-11 6.3795571369785494e-09 13692.097653407456 -1.964977828887244e-09 6.148287230915014e-09 -312.8934657953243 -6.832845309124503e-10 3.262539950747562e-09 -477.4789715187617 -1.166241308869291e-09 7.942423356977413e-09 -681.0274423119047 +r_2706 MLCL (2-18:1, 3-16:0, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -2.119219913726559e-09 6.3247241571439695e-09 -298.4458628468722 9.118637285665548e-12 2.414244123424837e-09 26475.931082597363 -8.830142799797943e-10 5.030868585421259e-09 -569.7380777960213 2.312067442930141e-09 1.4489561100225352e-08 626.6928391095013 -1.9494919161422587e-10 2.700985061405437e-09 -1385.481539595335 -1.9879662270988643e-10 3.283678149023624e-09 -1651.7776329709864 -1.9053638890220127e-10 3.639359688744707e-09 -1910.060177855434 -3.3356888713702056e-10 4.498487473761013e-09 -1348.5932433240282 -2.7063374367458034e-10 3.463018085192213e-09 -1279.5958250336548 +r_2707 MLCL (2-18:1, 3-16:0, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 4.081313589768544e-11 3.418330635720086e-09 8375.564779656992 5.114941789725584e-10 2.3969544372971696e-09 468.6181262339967 -8.90174295182234e-10 3.1066595933493806e-09 -348.99452951664864 -1.71906792587948e-10 4.459987475759385e-09 -2594.4219007388224 -6.451326790091482e-11 3.6692921213639553e-09 -5687.655021598935 -6.424597215845199e-11 4.560772710195097e-09 -7098.923958916383 -5.026506796372072e-10 5.203215504161158e-09 -1035.1553703093816 -4.4003280764321735e-10 3.0995719351344606e-09 -704.395645346431 -2.7264676264392073e-10 2.289824199432925e-09 -839.8501332742607 +r_2708 MLCL (2-18:1, 3-16:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 1.5668163203724911e-09 1.4729079832493204e-08 940.0642335019554 3.8495820285720703e-10 2.7596184335202564e-09 716.8618340999183 4.910465942183665e-10 2.864545935034515e-09 583.3552189877649 1.3483841844323798e-09 7.765373735981985e-09 575.9021668776783 4.6248749184755526e-10 7.30580634520261e-09 1579.6765261731107 9.655656271854486e-11 4.719935307143562e-09 4888.259455653801 -3.343558557953875e-11 3.732130485762961e-09 -11162.150807512333 4.949095001325238e-10 2.828460618303941e-09 571.5106736780267 -7.177326828039205e-11 2.7459146892630963e-09 -3825.8181005995248 +r_2709 MLCL (2-18:1, 3-16:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 9.098209767328063e-11 4.1882967798051814e-09 4603.429561324776 1.2648962353151123e-10 3.2797768359956e-09 2592.921651931819 4.92235422947685e-10 2.812673696223415e-09 571.4082256372569 -3.684580571551597e-11 3.6346364732222014e-09 -9864.451062042148 4.666694102745838e-10 5.123289476764882e-09 1097.8412906366389 -2.4987667407234997e-10 3.789865054983752e-09 -1516.6942128765586 1.3560568229717768e-10 4.4732421992515215e-09 3298.71294732951 1.005109817493405e-09 4.116002846097002e-09 409.5077746192652 -1.6401254882427502e-10 2.8908080212947078e-09 -1762.5529522085249 +r_2710 MLCL (2-18:1, 3-16:1, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 1.3999992046553695 37.39409158173302 2671.008058960871 1.675225244613217e-09 9.59339441544976e-09 572.6629565963068 7.254630668165789e-11 3.607188303159448e-09 4972.256298295423 -5.479561942841292e-10 5.4873439976784525e-09 -1001.4201965263528 -2.855478783343033e-11 4.192494336392504e-09 -14682.281517371908 1.3600142752822155e-09 9.294831942931889e-09 683.436351504702 -1.702633589017273e-10 3.589392539317585e-09 -2108.1415064701696 3.470824446412237e-10 2.493281851996958e-09 718.3543536966392 -1.6043521791549643e-10 2.0734896105302312e-09 -1292.4154917297324 +r_2711 MLCL (2-18:1, 3-16:1, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -1.399999206121981 37.394091581217 -2671.0080561259174 -9.49749424680405e-10 9.141691649872325e-09 -962.5372137444087 4.4368872528484445e-10 2.811827989006758e-09 633.7388869193347 8.054615167295023e-11 4.180182163512032e-09 5189.797497073792 -2.5352217966682784e-10 4.443601862331421e-09 -1752.7467885338813 -5.567133127106081e-10 1.0548539792134596e-08 -1894.7884936996213 8.47837134913184e-10 7.909283991171064e-09 932.8777503925858 3.4367107912593755e-10 3.225477955438489e-09 938.5363364417756 8.292659688443721e-10 6.089820531243649e-09 734.3627690076501 +r_2712 MLCL (2-18:1, 3-16:1, 4-18:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -2.7628272574556336e-10 3.0385410241418167e-09 -1099.7940663652255 -5.07701874087036e-10 1.926481359962162e-09 -379.4512997271116 -3.6204223668780605e-10 2.532719173260165e-09 -699.5645581109818 2.9999981073332003 54.6954710584964 1823.183518842852 2.2709565842078064e-10 2.211508956201162e-09 973.8226488255912 -7.778482510702705e-10 9.390046670368296e-09 -1207.1823337583105 -1.5827741089142123e-10 6.8588744681673795e-09 -4333.451267327455 -7.573911928623486e-10 3.065593345832132e-09 -404.7569307277758 -9.290157783972639e-10 5.26536205131771e-09 -566.7677744291385 +r_2713 MLCL (2-18:1, 3-16:1, 4-18:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 3.0842748663540856e-10 7.630058998654032e-09 2473.8583068225385 -5.152570864659482e-11 2.5734329666815363e-09 -4994.463995308111 -3.2838332652206835e-10 2.993758676896482e-09 -911.665859714498 -1.1672825261502072e-10 3.550254568955944e-09 -3041.469815079793 -2.6844711330139687e-10 6.750619536892434e-09 -2514.6925418092424 -5.7233278105847057e-11 3.317269534072341e-09 -5796.050206904788 -2.064936637386852e-10 3.404659780599305e-09 -1648.7962482509167 -4.74973872159157e-10 3.195713452617748e-09 -672.8187885557859 1.6115772335273194e-10 2.4961775030286155e-09 1548.9034289502451 +r_2714 MLCL (2-18:1, 3-16:1, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -3.0405558174733383e-10 8.181131761081478e-09 -2690.669815718065 -2.981809738292322e-10 2.5681891905089703e-09 -861.285399107915 -1.5459915992257542e-11 2.859114634387579e-09 -18493.72684702458 -1.6209461419632648e-10 3.6274153987454396e-09 -2237.838324691017 4.473650061222712e-11 2.963668171611478e-09 6624.720599629258 -3.6038693536880207e-10 2.997780458871539e-09 -831.8227340299558 -5.74764649862021e-11 3.3429673151527714e-09 -5816.236812676789 -4.586365281461073e-10 2.6349039261379963e-09 -574.5080830758856 2.628470091075933e-10 3.0058492831676592e-09 1143.5737060022054 +r_2715 MLCL (2-18:1, 3-16:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -1.6061076768822775e-10 7.742244914803659e-09 -4820.501779701747 2.684099375477355e-10 2.9143840468050278e-09 1085.7958812671448 -6.350675790746286e-10 2.70964427236667e-09 -426.670225602597 -2.9999981074383446 54.69547105877079 -1823.1835187880995 -3.6074024665128137e-10 7.239436156440229e-09 -2006.827966561328 4.406804066940783e-10 8.286238488193008e-09 1880.3283200982744 -2.706520541102588e-11 3.150696723855578e-09 -11641.133610506577 -3.772024322441407e-10 2.9724495804186032e-09 -788.0250301500478 2.0295190200944507e-10 2.638299801275033e-09 1299.963082460913 +r_2716 MLCL (1-16:0, 2-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 1.6550825761712272e-09 6.376012283644412e-09 385.2383183438684 1.0282927412741487e-10 1.991307628700227e-09 1936.5182197365448 6.826381861234942e-10 6.7763037298166076e-09 992.6640301646886 1.4427334387794979e-10 2.391085138600163e-09 1657.3298118209125 1.415047100805472e-10 3.186194217076108e-09 2251.652411614048 1.463542015566418e-09 6.099746682696308e-09 416.7797451537865 1.75676000824473e-10 2.095906206344209e-09 1193.0520939159687 7.936998274346618e-12 3.0854884890503437e-09 38874.753179965184 1.4181215796416366e-10 4.7847239392736405e-09 3373.9871164521405 +r_2717 MLCL (1-16:0, 2-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane -1.3223245747514778e-10 3.339251863469985e-09 -2525.289121316963 -8.485130477372151e-12 2.1313498619836687e-09 -25118.64570223732 3.964506439254479e-10 7.219902680968212e-09 1821.1353144695368 -5.660487645792033e-10 5.463172066727922e-09 -965.141593549666 4.5634574671259536e-10 7.613607858569682e-09 1668.3858485405583 -4.962407547674193e-10 3.9164911380644335e-09 -789.2320613408773 5.861771973737441e-10 2.362219303071185e-09 402.987238953453 3.3714749973534067e-10 4.4116908828391505e-09 1308.53436145969 -2.820262204211167e-10 5.504823096247687e-09 -1951.88344120202 +r_2718 MLCL (1-16:0, 2-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane -1.1745463515566992e-10 4.604548563674018e-09 -3920.278290908932 1.04637396711817e-10 2.081570440131442e-09 1989.31787825754 -8.631915148136131e-10 5.514716058407794e-09 -638.8751469132055 4.064130607709803e-10 2.8229373645838077e-09 694.5980917120608 -4.779863680154961e-10 7.888663460612049e-09 -1650.395071592565 1.4109757653123248e-10 2.772053101099762e-09 1964.6355162493933 9.276819505986667e-11 1.6783938691870023e-09 1809.234154123484 -8.002220833599051e-11 2.3585425181816404e-09 -2947.3599482268605 4.197690011331852e-10 2.8669112486812276e-09 682.9735499624489 +r_2719 MLCL (1-16:0, 2-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -2.4140360127870777e-10 3.364923157113217e-09 -1393.899320179698 -2.7200245320022117e-10 2.285677048676469e-09 -840.3148654670335 -1.2763749181703758e-11 3.8944919153715855e-09 -30512.1313489469 3.1979109454964447e-10 3.085767800863128e-09 964.9323741202844 2.486633852392418e-10 3.274506957729961e-09 1316.843231495268 -2.6354909237649715e-10 3.404028794430476e-09 -1291.610896374326 -4.434251038230356e-11 2.5396477552355757e-09 -5727.343204838288 3.105820915826554e-10 4.8499101359074115e-09 1561.5549857344884 2.3701272944406013e-10 1.376165295537075e-09 580.6292762270721 +r_2720 MLCL (1-16:0, 2-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane 3.653772928398552e-11 1.864393552870793e-09 5102.653036755508 -6.590076938139923e-10 3.230290939533061e-09 -490.1749964158724 -2.21110366931106e-10 6.6928285721249744e-09 -3026.917581937865 8.625271813946779e-10 6.006439011459935e-09 696.3767798885737 -5.003653384957904e-10 6.669364000918648e-09 -1332.8988816388123 -4.0044090396158445e-11 3.970454591306743e-09 -9915.207342773458 -3.2860786740146257e-11 2.0890322503003808e-09 -6357.219219429689 6.743723641849077e-11 4.218555917605051e-09 6255.529054343565 1.4847440722650823e-10 2.91291266476828e-09 1961.89546682239 +r_2721 MLCL (1-16:0, 2-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 1.263823883632255e-10 1.745393156575987e-09 1381.0414403308257 -4.089467478681498e-11 2.737837205532863e-09 -6694.850172559828 2.39488428239029e-10 3.415032014370681e-09 1425.9695299190826 -1.8725722329754047e-10 4.045828375566459e-09 -2160.5726627366894 9.297838872521468e-11 4.008400163329714e-09 4311.109515111098 4.99557777785522e-10 6.285610357557637e-09 1258.2349103683202 -1.9019471223795688e-10 2.0016854107623648e-09 -1052.4400953155894 2.3861934420104664e-10 3.670786757455147e-09 1538.3441647389484 1.8631744972651968e-11 2.31351980853288e-09 12417.086064288173 +r_2722 MLCL (1-16:0, 2-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -8.607366478083897e-11 1.667655498526299e-09 -1937.474723276264 4.10726519555395e-10 6.0350159198925605e-09 1469.351413301817 2.6858031898745167e-10 3.4514429717136358e-09 1285.0692056385897 -2.3614670864415077e-10 3.094260808612377e-09 -1310.3129094528756 1.4767969960030018e-10 3.607604534293793e-09 2442.857443547007 -1.6628500070525477e-12 3.356891780398621e-09 -201875.80155523555 1.1553897978696939e-10 2.2665974319292668e-09 1961.759949852782 -1.3379809106763707e-10 1.6993041201817515e-09 -1270.0510946174309 1.1632997485809252e-10 2.1013008531754347e-09 1806.3279526525723 +r_2723 MLCL (1-16:0, 2-16:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 5.29332752691155e-10 2.5342803594445846e-09 478.7688550463148 6.701874702564812e-12 3.959103125023557e-09 59074.56198052174 -1.8639168705002167e-10 3.218701391577496e-09 -1726.8481457081816 -2.7154419356317063e-10 3.818493082042114e-09 -1406.2142268395803 4.15540731723093e-10 4.209832707474855e-09 1013.0974862604306 1.2230971440865412e-10 3.540501272776582e-09 2894.7016104929035 3.1400927738165026e-11 2.3675996744135644e-09 7539.903579141573 5.088749946780849e-11 2.119229410212884e-09 4164.538309754268 -3.3288004047058343e-10 4.676279992692098e-09 -1404.794347561773 +r_2724 MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane -2.566781286815776e-10 4.4200815777011095e-09 -1722.032804432842 6.047400021961671e-10 3.86385536236681e-09 638.9283573659546 -3.9821297308354796e-11 2.056588757314897e-09 -5164.544844909938 -1.2511805922966179e-10 2.7118004373656473e-09 -2167.39330362212 2.2151615425482492e-10 7.111742178496961e-09 3210.484672064072 -5.8186898075146826e-11 3.1231516062841122e-09 -5367.448187821673 2.1684249851607642e-09 6.5955076574311245e-09 304.16120929090573 6.030112508844525e-10 1.885229488874812e-09 312.6358730636777 6.197817029951932e-10 2.6895859555436552e-09 433.95697913407326 +r_2725 MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 9.863538806698452e-10 5.6188627031790964e-09 569.659917530132 1.4237001691677826e-10 2.2843003714253367e-09 1604.4813514074483 2.570446350925661e-09 7.250222613182913e-09 282.06084171225694 -2.1999987964890937 46.85719502275592 -2129.873666182627 5.935856462172186e-10 3.6797107898937204e-09 619.9123603044734 -1.4012023094577639e-10 2.082336568373984e-09 -1486.1070056184856 6.718674448972259e-11 3.1733462573697037e-09 4723.173122125487 2.7028505529171884e-10 1.8393107675500478e-09 680.5077571029145 5.904247278154037e-10 2.620804460737072e-09 443.8846032811261 +r_2726 MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane -1.0815102616538227e-10 2.0940360801576067e-09 -1936.2147123370328 5.584142774885566e-10 2.793937742998412e-09 500.3342241828098 -4.5895317097598576e-10 3.691685516824096e-09 -804.3708487673267 -1.453729420770907e-10 3.4731072193413763e-09 -2389.1015547443503 1.225899540608815e-09 7.1203441196058124e-09 580.8260696524657 -8.551693675578812e-10 6.440777756775903e-09 -753.1581463411064 -4.458346339164871e-11 3.2612000652220687e-09 -7314.8199290254115 4.4171275769646335e-10 2.1991210967639835e-09 497.86225515251647 6.50038649945305e-10 2.826856014182135e-09 434.8750669548633 +r_2727 MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -3.1378524610736667e-10 2.9787080694500806e-09 -949.2823854537978 8.594348475477776e-10 3.265383879004949e-09 379.9454825833578 2.527155169860572e-10 5.1357643481173045e-09 2032.2315025874148 2.1999987968999304 46.85719502273676 2129.8736657840145 2.47155308781177e-10 3.837762749572772e-09 1552.7737472030583 1.6826975957155567e-09 7.411725362681274e-09 440.46686591535087 2.002618755590344e-10 4.159944133205416e-09 2077.2521587510664 2.5962280625646736e-10 2.7185239893141366e-09 1047.1052325921837 1.2039202393699634e-09 3.562847921354618e-09 295.93720620720944 +r_2728 MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -1.2689203822014416e-10 1.269799227364871e-09 -1000.6925928338426 -4.296828281782115e-10 3.266602041667286e-09 -760.2356499833079 -1.999999042229876 44.681057319516405 -2234.0539358308783 -3.3305853809166257e-11 1.1069754082831664e-09 -3323.666207825937 1.9998165580342918e-11 3.321537402172325e-09 16609.210423966142 -1.9258789269064603e-10 4.0024375930602174e-09 -2078.239466220928 -5.190459763792734e-10 4.266363368193483e-09 -821.9625162985558 -4.875847244522968e-10 1.7011202152051295e-09 -348.8871020551342 -4.117368618605088e-09 8.548221585034696e-09 -207.61370615222503 +r_2729 MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -6.833489569035335e-11 1.219312751535964e-09 -1784.3193279478314 -6.33366083115225e-10 7.810401450568457e-09 -1233.157514869256 1.999999039568872 44.68105731934518 2234.0539387947315 -7.466708481241131e-11 1.3122966403083279e-09 -1757.530300808255 -2.593329403620604e-09 6.601877885687785e-09 -254.5715124530944 3.4407515202930376e-10 5.75766689265295e-09 1673.3748016080476 -8.497297014494103e-10 3.309789555755176e-09 -389.5108703520148 -3.9933194888329424e-10 1.8697487187648123e-09 -468.2191655321951 -8.709052105394593e-10 4.697629656622828e-09 -539.3962052096351 +r_2730 MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -3.313743774958663e-10 1.5187826338848971e-09 -458.3283250087261 -2.1566017241892718e-10 2.951171547749877e-09 -1368.4360513340994 1.5888909166139403e-10 3.626322328007329e-09 2282.2978532316906 -4.817834763906427e-11 1.425202511102282e-09 -2958.180554010305 -9.737811343403384e-11 3.929551427127852e-09 -4035.353827007359 -6.527941523872313e-10 8.538373200340479e-09 -1307.9732974194285 -3.276361108068578e-10 3.2027354752884113e-09 -977.5282301456784 -4.96625224139794e-10 1.8247776676069503e-09 -367.4355588296292 -1.122633357575082e-09 5.145046326657682e-09 -458.3015720975117 +r_2731 MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 5.983010112185335e-10 2.0700485022917343e-09 345.98779936469725 -1.40129215448226e-09 8.681995679060068e-09 -619.5707048875779 -3.0607064877056033e-10 2.735374987518004e-09 -893.7070570162781 1.3293442129695948e-10 2.1567362429162603e-09 1622.4061622823558 -2.1436889102390727e-10 4.982662447090562e-09 -2324.3402637815 -3.4804891320768085e-10 4.297382612312551e-09 -1234.7065165947813 -1.4011767688497603e-09 6.723982659095065e-09 -479.8811119752468 -5.395616695271517e-10 3.3128735260043067e-09 -613.9934901060642 -6.845373787192021e-10 3.744123615680407e-09 -546.9567816275886 +r_2732 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 1.3025155561472218e-10 4.714679389811466e-09 3619.672231598722 9.528192453786987e-10 1.0746325984733605e-08 1127.8451854173522 -2.3345148181157396e-10 3.971793412113872e-09 -1701.3357042298114 -1.778612655852772e-11 4.010578805404237e-09 -22548.916382703508 1.858343604679563e-10 5.332972286304585e-09 2869.745009951568 6.630301965615605e-09 1.723229016878648e-08 259.9020415382621 3.45320986009097e-10 5.749134626996442e-09 1664.866851400971 0.5999997988640707 24.489988815056844 4081.666170792337 -2.2069846761766197e-11 3.649933956804262e-09 -16538.102852292606 +r_2733 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane -1.6719978313675627e-09 6.780521483489977e-09 -405.5341075379292 2.1720660350199795e-10 6.541622785545193e-09 3011.7052981241523 -2.7650342524922247e-10 5.2475057719946395e-09 -1897.8085957759376 -1.1048225729852166e-10 4.815586764481783e-09 -4358.6969367127695 2.073811149384301e-10 4.691570861504366e-09 2262.294164489017 -4.327578967793653e-09 1.464723136249432e-08 -338.4624861036788 -3.5271327288217116e-10 9.444720639321693e-09 -2677.7332653644803 4.799915823446546 69.12123670380107 1440.0510185232592 -8.326486740544322e-10 1.0773387120026952e-08 -1293.869486102451 +r_2734 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 2.6149994829543947e-10 3.509466310948173e-09 1342.0523919122231 4.014745834519088e-10 5.105303295926069e-09 1271.6379831645347 -8.680992148615805e-10 4.347784040957907e-09 -500.83953153340485 2.4910166302619086e-09 1.0122551188318802e-08 406.36224846297006 7.375268899770836e-10 4.944305432352943e-09 670.3898528373074 -1.2983922585827342e-09 1.535151230783856e-08 -1182.3478002399345 9.425056990728636e-11 5.223114099312349e-09 5541.732113079305 -5.399915622481245 73.29218148154347 -1357.2838282214848 -1.6887185990087953e-11 4.077663156056635e-09 -24146.49284048892 +r_2735 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -1.7502981897622778e-10 4.359306876832323e-09 -2490.6081159944497 -1.4503258603866102e-10 6.369210808538113e-09 -4391.572254555459 2.340434824921573e-09 9.025211609461903e-09 385.6211466928729 -2.802522772355085e-10 4.74290435231663e-09 -1692.3696032382122 1.0402464801493404e-10 4.149071241193484e-09 3988.546292026705 1.2110222948385174e-10 4.420641823123379e-09 3650.33892601692 9.370939434435992e-11 4.149189397323185e-09 4427.719788771543 -5.708193561527037e-10 4.741342664426945e-09 -830.6205130084193 -5.788490815025571e-10 1.1632807270045076e-08 -2009.644247832098 +r_2736 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -5.723066924344297e-10 4.848006969968849e-09 -847.0994720237865 -5.718369276727602e-10 8.845620397885255e-09 -1546.878134275941 -1.99304694568908e-10 2.8648709217425203e-09 -1437.432734807967 3.828563612275324e-11 3.842501059518367e-09 10036.40385443344 1.2467537241045803e-10 3.582583279988799e-09 2873.5292389535985 -9.228214011273979e-10 6.776027643448434e-09 -734.272919458766 4.503774050890122e-10 5.675642225603187e-09 1260.1969285029868 -1.5999991960590865 39.971964601821256 -2498.2490428917145 2.0205110378457816e-10 4.897152798453325e-09 2423.71989399006 +r_2737 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -3.736944698100557e-11 3.3531592754536116e-09 -8972.996783061792 -1.0084016138355855e-09 1.2531408416697621e-08 -1242.700154855246 1.8760510523620688e-11 2.557768852897461e-09 13633.79130688936 -2.2302817607809915e-09 8.663616665550079e-09 -388.4539082862914 -1.3759258409380495e-10 4.438251408280372e-09 -3225.6472523654006 4.0416062335491537e-10 3.131957807115271e-09 774.9289827190631 -4.3519440066021015e-11 4.833170866138073e-09 -11105.774474133694 1.5999991967828795 39.97196460171204 2498.2490417547533 2.0111414236923656e-10 6.443609418629669e-09 3203.956391490108 +r_2738 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -1.4428639062479573e-10 3.224986947315766e-09 -2235.1289912726875 -3.5418284889125406e-11 9.886654803241448e-09 -27913.98520338002 2.002524606955444e-10 3.027782474164521e-09 1511.982656117189 1.2293128546182116e-10 4.4138950493813445e-09 3590.538431937385 1.4122867457586422e-11 3.935373821759852e-09 27865.26060361684 1.722546887780048e-11 3.196717389740236e-09 18558.08635699921 -1.6044897188133308e-10 5.069405478553162e-09 -3159.512597128049 3.703164589810865e-10 4.5205178954769654e-09 1220.717520337881 2.0966293883366127e-10 5.190625960842634e-09 2475.700278607981 +r_2739 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 2.27961765312594e-09 7.454672267062514e-09 327.0141489227479 5.082084270275754e-10 3.920590283259678e-09 771.4532217008962 -6.344780894707734e-10 3.330051873478534e-09 -524.8489945895805 3.3489228601315875e-10 6.519219431786759e-09 1946.6615697235263 -1.0804426607864183e-09 7.583689066243038e-09 -701.9057411823337 -2.0150284875509903e-10 7.277327329089358e-09 -3611.525779436508 3.501772837751099e-11 4.95309201520084e-09 14144.526914492277 1.7189047843045408e-10 4.976711922518781e-09 2895.2807438559366 1.213043959687562e-09 7.649799613508494e-09 630.6283916931433 +r_2740 MLCL (1-16:1, 2-16:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 3.5545786419383136e-11 2.794879798280512e-09 7862.75978059797 -1.399999134497945 64.79873074656102 -4628.483629012996 2.820239316838798e-10 4.764949318767547e-09 1689.554957381621 -1.3496790856481472e-10 2.6935373855352558e-09 -1995.6872816487007 -2.1999984705965496 46.85718801667724 -2129.8736632290243 1.0177486832934764e-10 3.378469598623289e-09 3319.5519228680537 -2.3933036296956433e-10 2.62714542084085e-09 -1097.706696402305 2.8371719990311897e-10 2.7214389460656152e-09 959.2083056631412 -2.159241191203053e-10 3.06826862616887e-09 -1420.9939300293445 +r_2741 MLCL (1-16:1, 2-16:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 5.1213945103844415e-11 2.270794274175067e-09 4433.937416011734 3.9999978449025577 63.12521019926873 1578.1311052382953 2.2191804523690127e-10 4.983513899532359e-09 2245.6550994816007 -1.314224612050452e-10 3.651147908451803e-09 -2778.176481381889 3.634578381507858e-11 2.7187502529815883e-09 7480.235580594839 -7.885177410952793e-10 5.7148150619738794e-09 -724.7541512554676 -1.2992445127273028e-10 2.797710804350842e-09 -2153.336632900639 5.642680901923816e-10 4.646637872066205e-09 823.4805321849725 -3.6514433749224516e-10 3.742593756613845e-09 -1024.962835879477 +r_2742 MLCL (1-16:1, 2-16:1, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 2.0854725000682e-10 2.527737205779164e-09 1212.0693059709497 1.7999651861938001e-10 2.964048433875805e-09 1646.725423697539 3.7234050941758335e-09 1.7884222922686725e-08 480.31902171110266 1.1261102876103059e-10 6.561940639150106e-09 5827.085243200342 2.1999984704895925 46.857188016682045 2129.873663332791 1.39941602099091e-10 3.239157800172894e-09 2314.6496478433087 5.917407235455462e-10 5.229937171689552e-09 883.8224180944012 -6.71359752735705e-11 2.249559453022182e-09 -3350.751134329272 1.1519446492685607e-09 6.255909404439089e-09 543.0737847006228 +r_2743 MLCL (1-16:1, 2-16:1, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -3.3180192389606556e-10 2.854976691824589e-09 -860.4460933502269 -2.599998710814039 50.92893185328484 -1958.806042536052 -4.7258893448303585e-09 1.75363446087949e-08 -371.0697252778014 -4.348729516616855e-11 3.298946783280025e-09 -7586.001315268004 -1.1236809723111688e-10 4.553224538166824e-09 -4052.0616174551983 -7.561613816587896e-11 8.188556580568901e-09 -10829.112381547022 -4.31083761808698e-10 3.3037059340139318e-09 -766.3721593577485 -3.66088462391102e-10 2.0066874391189033e-09 -548.1427701961024 -2.42242702410766e-10 2.0241924971982166e-09 -835.6051501464158 +r_2744 MLCL (1-16:1, 2-16:1, 4-18:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -1.6566547337764168e-10 4.109636989576388e-09 -2480.68405913904 -3.0525639138118424e-10 5.713897963181412e-09 -1871.835651770603 4.948580659901763e-10 5.8152991433720405e-09 1175.144863353098 -6.088901270328082e-12 1.3512201543214472e-09 -22191.52675222538 3.8383473996850166e-10 2.48579303462854e-09 647.6206491451322 -6.596469553257495e-10 9.033486475166126e-09 -1369.4426089945605 -1.3152987465463992e-10 2.7536486523492247e-09 -2093.553772159765 -3.504372491882612e-10 1.6088407866344734e-09 -459.0952561010932 -7.946821938608911e-11 1.977241775620008e-09 -2488.0912028665944 +r_2745 MLCL (1-16:1, 2-16:1, 4-18:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 1.956619833610213e-11 2.037894459718305e-09 10415.382818429936 1.6673275553392164e-10 5.206118545826353e-09 3122.4329791437845 1.3474813718978e-10 1.8183561722474715e-09 1349.4480964041002 1.4153943305022823e-10 1.5492271524751762e-09 1094.5551491119795 1.4718537387361204e-10 4.377870973217706e-09 2974.3926709572247 5.548514728081023e-10 7.718786276132826e-09 1391.1445953397329 -3.3039131793534046e-10 2.636592397001877e-09 -798.0210901056042 -1.694332167021792e-10 1.3413593071788342e-09 -791.6743441969855 -2.069429590093976e-10 1.893889121734724e-09 -915.174466819487 +r_2746 MLCL (1-16:1, 2-16:1, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 2.2882642015463312e-09 1.2226614773424343e-08 534.3183171402154 -4.5540390258577045e-11 2.360798249280821e-09 -5183.9657848259 3.1847622739880665e-11 3.8498341439579624e-09 12088.293607978065 -2.442189748821552e-11 1.7252197364456283e-09 -7064.232978940771 -8.135755330386232e-10 5.399903839651514e-09 -663.724954889365 -3.5135130327048946e-11 8.507961831162612e-09 -24214.97160240421 9.583325250670878e-10 4.913363568940918e-09 512.6992396086066 1.706243999453705e-10 1.828988829530504e-09 1071.938614943759 1.4105538005169935e-10 2.51915100211068e-09 1785.9304630474678 +r_2747 MLCL (1-16:1, 2-16:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -2.551238584206616e-09 1.1679754344973817e-08 -457.80721635667743 3.8428070727863296e-10 2.970259035878306e-09 772.9399315705539 -3.2897887165833326e-10 3.85183503403701e-09 -1170.8457186385515 1.0659362637387804e-10 2.298285606476194e-09 2156.1191645877007 4.368091563535095e-10 2.056647329370162e-09 470.8342990195284 6.263443563012672e-10 9.010453500383241e-09 1438.5782213465457 -1.6528295263659354e-10 3.2897066729990195e-09 -1990.348442184521 -2.157814193581729e-11 1.507778658778229e-09 -6987.527764267255 -2.4983193699435954e-10 1.9677720612333075e-09 -787.6383159442637 +r_2748 MLCL (1-18:0, 2-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane -1.0346827837943e-10 4.3256497092977725e-09 -4180.653024335749 2.2096565301773478e-10 2.893159330278471e-09 1309.3253592884255 3.134112169842117e-10 1.7730965490339527e-09 565.7412539651615 -1.5324700695483418e-10 2.6950401773451756e-09 -1758.6250008389873 -3.713571723131233e-10 3.843891265068931e-09 -1035.0927763495067 -2.0269374177187517e-10 5.652072571419846e-09 -2788.4790729163506 3.171984412562089e-10 2.1357087305032635e-09 673.3036650637888 3.393635112736013e-10 4.8144572868513565e-09 1418.67264066874 -1.1999997976055914 34.623682074402254 -2885.307326175246 +r_2749 MLCL (1-18:0, 2-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 1.0866140775086375e-09 6.513394186868006e-09 599.4211120291905 1.4251602286903896e-11 8.508954947322557e-09 59705.25121334334 1.9000320734966743e-10 2.19803167637962e-09 1156.8392486841185 -1.7977988760994116e-10 3.0357228679088044e-09 -1688.5775757604492 5.25062882299533e-12 3.741114336494387e-09 71250.78657455338 3.8523808697376296e-10 6.843843667527562e-09 1776.523116208307 3.3029367676768904e-10 2.1944428724269395e-09 664.3914270179606 -5.5194840063067036e-11 2.2769430257884983e-09 -4125.2824053603645 1.5734359160382772e-10 1.795042010031999e-09 1140.842147897386 +r_2750 MLCL (1-18:0, 2-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 1.606048165407597e-11 3.3132425619015504e-09 20629.78329831526 2.601104890633802e-10 4.369375654254421e-09 1679.8152469698175 -2.6827708087778416e-10 2.185361130463426e-09 -814.5910650708869 6.983980874238674e-10 6.269994468454768e-09 897.7679895405298 9.88948947238298e-10 6.537868524606125e-09 661.0926219056638 1.5205481329909014e-10 2.5854399995146486e-09 1700.3342041064598 1.7809178353486574e-10 1.59276356852157e-09 894.3498329386701 2.7749473180637057e-10 6.366698308055376e-09 2294.3492536276003 1.1999997981013282 34.62368207439025 2885.307324982285 +r_2751 MLCL (1-18:0, 2-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -2.9721758175255543e-10 2.9325011170542324e-09 -986.6512942345546 -3.6942444144141126e-10 8.023824270099743e-09 -2171.9798069647422 1.7807215633258339e-10 2.007892129427538e-09 1127.5721992591705 -3.0045020447086157e-10 3.258657755840217e-09 -1084.591625284199 -2.8009000563684784e-10 4.753314025029828e-09 -1697.066631928582 -6.470531939708709e-11 3.358617111179401e-09 -5190.635240617636 -4.7145018204710974e-11 2.420077289345902e-09 -5133.261968078051 -2.3642894756797564e-11 6.260700349986887e-09 -26480.26146708145 2.9652591279505646e-11 3.207768674331822e-09 10817.835932432885 +r_2752 MLCL (1-18:0, 2-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -2.0842699675793647e-10 3.1320947480144542e-09 -1502.7298750804414 -4.313022906220427e-10 2.0272305761281834e-09 -470.0254601487102 -4.108044899417645e-10 3.0672525638172193e-09 -746.6453358998175 1.1807198815151333e-10 6.724835208031595e-09 5695.538216399045 -1.7508504916004558e-11 2.1842232866005086e-09 -12475.213029776778 -1.793106976973566e-10 1.512095657995655e-09 -843.282457440322 8.757692231688152e-11 4.486607158328224e-09 5123.047304738838 -8.751838563250423e-10 4.277147951135193e-09 -488.7142193293228 9.386568132603982e-11 1.416451274593774e-09 1509.019329091929 +r_2753 MLCL (1-18:0, 2-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 1.4583382350243906e-10 2.07471035274096e-09 1422.653745827531 -9.156744623566037e-12 2.2460140352972077e-09 -24528.521080699444 3.61999609233057e-10 7.1102720716641675e-09 1964.1656759597608 6.287438397508078e-11 7.631012048966233e-09 12136.9174002415 -3.44033231546529e-10 1.7713351114863955e-09 -514.8732590522524 1.0918650473590644e-10 1.733722020318137e-09 1587.8537595021996 -1.0799352455946663e-09 7.0702902794945025e-09 -654.6957614668135 4.403872622346267e-10 1.842561843212636e-09 418.39580778586816 -2.8853446287599227e-10 2.5949557724096262e-09 -899.3573060715798 +r_2754 MLCL (1-18:0, 2-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -2.0090604249547422e-10 2.051607308082696e-09 -1021.1775029757564 -2.8522762190022474e-10 2.1522774278637278e-09 -754.5823975689893 5.207605392899665e-10 6.881057614750772e-09 1321.3477396218968 -2.189366272794737e-10 3.460746675906809e-09 -1580.7070378814 -1.4461489136477372e-10 2.042141733314005e-09 -1412.124100112863 -1.9597261796836427e-10 1.7683423964552702e-09 -902.341569341454 4.4359340375500736e-11 2.4555013293664073e-09 5535.477553499777 2.2075818271841827e-10 2.153972679352706e-09 975.7158954783316 7.894328664413445e-11 1.441436145079819e-09 1825.9135214088767 +r_2755 MLCL (1-18:0, 2-16:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 4.329393023035956e-10 2.817053441511124e-09 650.6809214414278 5.40557080370292e-10 2.3714947125478517e-09 438.7130977774507 -5.931326747559095e-10 2.50956157188452e-09 -423.10290407070806 -1.1160854707529634e-10 2.9867386695924597e-09 -2676.0841780132364 4.534327820627116e-10 2.5786069761044275e-09 568.6856085645336 6.490340245368015e-10 3.716190503564261e-09 572.5725251794631 1.9761525245972712e-10 3.68203518626349e-09 1863.234310324233 3.4545600140769915e-10 2.06856167120305e-09 598.791644311827 3.8175749596118976e-10 2.4562214459917678e-09 643.3983541848964 +r_2756 MLCL (1-18:0, 2-16:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane -2.365419514450543e-10 4.696818838117412e-09 -1985.6176925167645 5.53247609406737e-10 2.2291626342001515e-09 402.9231389884441 5.957969969101183e-10 2.568189445165581e-09 431.05108929460016 6.9616918784474435e-09 1.6073742049055684e-08 230.8884439257941 3.905507835180656e-10 3.1626539131829222e-09 809.7932577919483 -7.321081551230759e-11 2.9777747934063887e-09 -4067.3973818879113 6.191147460073705e-10 2.508773248125614e-09 405.2194305344081 5.354508565528387e-10 2.6404289317837006e-09 493.12255260593486 -4.474479651335658e-10 6.342211248262212e-09 -1417.4187263024037 +r_2757 MLCL (1-18:0, 2-16:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 1.6415592349915478e-10 8.052988201882288e-09 4905.694555654431 4.5443714125505877e-10 1.816396541517659e-09 399.7024839345565 -1.6381587796060066e-10 8.633764686836515e-09 -5270.407725014922 2.2780425909500468e-10 3.753980861986136e-09 1647.897575269019 7.262167871303226e-10 3.082335154056172e-09 424.4373317554604 -3.4723843477709105e-10 2.924276182641223e-09 -842.1522186961981 6.138046748587229e-10 2.27655190460251e-09 370.8919136411752 2.724223707516585e-10 2.094499399424594e-09 768.8426591566337 1.909547904881324e-10 3.474386629107132e-09 1819.4812605777809 +r_2758 MLCL (1-18:0, 2-16:1, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 6.58616129196807e-12 2.7723215390154342e-09 42093.13158480229 7.418610132233721e-10 2.3523042312503557e-09 317.0815273105723 5.774708002182704e-10 7.0069056950397106e-09 1213.3783547828325 -4.110974997393324e-09 1.6203656570357007e-08 -394.1560476682874 8.96645489597294e-10 5.578775327540617e-09 622.1829465786064 5.748620142334412e-10 5.957029968041037e-09 1036.2538871148988 4.853468359793199e-10 2.056118314734783e-09 423.6389654392209 3.9486632904377936e-10 1.9247138052577283e-09 487.4342691914693 -4.3883061636339344e-10 6.213139313402223e-09 -1415.839980558046 +r_2759 MLCL (1-18:0, 2-16:1, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -6.1640468166591e-10 8.648021476762804e-09 -1402.977902989065 6.586890919572718e-10 2.6356786051683164e-09 400.1400110234845 8.550716095360627e-10 5.746066936111312e-09 671.9983299678213 4.2619929383455484e-10 4.64572430801154e-09 1090.0356652901803 2.395969209839934e-10 3.6572443341437246e-09 1526.4154143233136 3.3231946523876857e-10 6.603529581968237e-09 1987.1028551468264 6.179071784431161e-10 2.7302046868491313e-09 441.8470576322123 1.0324830039491059e-09 3.425734893666896e-09 331.7957661834558 3.4495738927376326e-10 4.896599533859164e-09 1419.4795317091034 +r_2760 MLCL (1-18:0, 2-16:1, 4-18:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -2.0829006036919027e-10 2.560474341003835e-09 -1229.2830183377168 -3.9541816141054735e-10 3.590039132576929e-09 -907.9095203342292 -6.237989182111641e-10 3.9193336585094285e-09 -628.3008104195976 -2.9999981125509616 54.69547105893156 -1823.1835156863765 -2.9757444353578246e-10 4.790557212922088e-09 -1609.8684940818978 -5.227266065171554e-10 4.2213758880935855e-09 -807.5685904377324 -2.034607874719354e-09 9.555196317316346e-09 -469.63331047926624 -3.151325104412622e-10 2.702095417888482e-09 -857.4473684434815 -2.700137214944032e-11 1.7982348823552451e-09 -6659.790741014318 +r_2761 MLCL (1-18:0, 2-16:1, 4-18:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -1.3955658254070539e-10 2.257929266884998e-09 -1617.9310397103 1.4509132329373962e-10 2.698035326302642e-09 1859.54284863777 -1.6852177808687602e-10 4.262332645781306e-09 -2529.2473733477914 -4.829341358910244e-10 4.791105707407325e-09 -992.082636396706 -3.512078501752553e-09 7.683614995304833e-09 -218.77685796233345 7.007409658546362e-11 4.254718335585743e-09 6071.7419744350345 -1.4945783040649002e-10 3.798870248994466e-09 -2541.7672922605902 -2.992585139534826e-09 6.903031940921356e-09 -230.67119627528388 -1.792914878079116e-10 1.4330285245258263e-09 -799.2730397000984 +r_2762 MLCL (1-18:0, 2-16:1, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -3.688323661566309e-10 2.433174110341863e-09 -659.6964728709776 -5.032131687649312e-09 8.121349535683709e-09 -161.3898450952002 -9.361281796867191e-10 8.420119972817256e-09 -899.4622911186266 -3.600403272445749e-10 4.299746748925935e-09 -1194.2403179755815 -8.502699804962157e-11 3.1999456050128276e-09 -3763.446526884727 -5.494572736615674e-10 4.365073470927775e-09 -794.4336493789681 -1.7660403138781068e-10 3.5963464469544087e-09 -2036.3897803992209 -1.2135707044288412e-10 3.5168905985103044e-09 -2897.969261844951 -1.0537636509068843e-10 2.0102415816650115e-09 -1907.6778554042623 +r_2763 MLCL (1-18:0, 2-16:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 4.836065794958435e-10 2.7429650273286604e-09 567.1893525907327 2.777369783567138e-10 3.4758789942066142e-09 1251.500255663594 -2.221534693999905e-09 7.479040260985954e-09 -336.66097050772737 2.99999810675226 54.69547105900137 1823.1835192127385 -8.240138175931653e-11 5.0179813821570215e-09 -6089.681113374867 1.8548791711840408e-10 8.624715258983925e-09 4649.745057775617 -1.7999969809454815e-09 9.67209809871316e-09 -537.3396845161768 -3.2202731362443515e-10 4.535476906560198e-09 -1408.4137322120769 2.1245762080809823e-10 2.149679612678787e-09 1011.8157232968732 +r_2764 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane -2.92106522416383e-10 6.331698579175169e-09 -2167.5991781346297 1.6388807082662727e-09 1.2192759112662193e-08 743.968676375511 4.999998117753883 70.54069762085476 1410.814483517112 -2.6320227728684517e-10 2.3497603547678526e-09 -892.7583678187625 -4.4046893111330954e-10 3.6200575522635997e-09 -821.8644486714885 8.51595610831175e-10 1.2478799301123233e-08 1465.3433087734752 2.0363482178447047e-10 2.185568803132873e-09 1073.2785208249427 -2.2000833608083505 58.27376074426271 -2648.706943670165 4.5753984707086407e-10 4.150726317191468e-09 907.183569641881 +r_2765 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane -1.0743629408228524e-10 3.960844772535609e-09 -3686.691547180514 -5.937027736510547e-10 4.6613877970892415e-09 -785.1382887136286 -6.799997314643713 82.18944130153832 -1208.6687317441192 -1.9024576574992382e-10 2.762418417904564e-09 -1452.0262288180097 1.878341405805048e-09 1.2216603071523605e-08 650.3931092488283 1.556238278098975e-10 4.690179980614698e-09 3013.792968994436 3.3451333285095037e-10 3.0594565668659156e-09 914.5992898971002 1.400083764373227 61.63433390194194 4402.189031135125 1.9522700450443039e-10 7.638744818587345e-09 3912.750102363013 +r_2766 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 4.020878344075426e-09 1.011959092218592e-08 251.67612785640875 -5.757549384246403e-10 1.2582460834148426e-08 -2185.384786898414 -5.248390100485635e-10 4.609309651926604e-09 -878.2330512170012 -1.6745287828857162e-10 2.2001843856122408e-09 -1313.912551458603 1.5783193898410355e-10 1.395731878845246e-08 8843.152329173505 -1.0874652948569106e-09 1.0267522234716269e-08 -944.1701066945104 1.7184038495864328e-10 2.319667082029008e-09 1349.8963486303176 9.502363446589476e-11 2.597447346724098e-09 2733.475057362025 1.566146461302799e-09 1.2295031868981838e-08 785.049940907456 +r_2767 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -4.2559338152835214e-10 3.798984561445488e-09 -892.6324342269893 -8.351523329076347e-10 5.212868628868515e-09 -624.1817718115675 1.7999991985459218 42.39242652221014 2355.135855419028 -4.4143096963509134e-11 2.419549218182245e-09 -5481.149680509196 -1.6411457966239583e-09 1.4464300103575684e-08 -881.3537550003513 3.5347366874134547e-10 4.539492174403272e-09 1284.251862541152 2.606636558872765e-10 2.676418197293354e-09 1026.7707587323823 0.7999995989674105 28.27576885791868 3534.4728790383483 5.532228549863126e-10 3.6428533372743357e-09 658.4784602516942 +r_2768 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -1.087368824771732e-10 3.57828784779195e-09 -3290.7765665832185 3.3890029831362595e-11 3.829289228264249e-09 11299.161574418378 -1.5999993991537906 39.97196591865421 -2498.248808080467 2.1674606234702136e-10 2.8091978753999794e-09 1296.0779286971829 -7.382293808751878e-10 1.1047814507096231e-08 -1496.528693290261 4.502224230471316e-11 2.779096814097113e-09 6172.719686611839 1.4292644356000995e-10 3.245791232841105e-09 2270.9522128970543 -1.130079963771003e-09 9.58952244805234e-09 -848.5702565730593 -6.136880686097157e-10 6.7016060287007415e-09 -1092.0215613581902 +r_2769 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -9.440312400029327e-12 4.327698781391227e-09 -45842.74966766759 4.0597927720096285e-10 3.587118878419014e-09 883.5719160718056 1.5999993982485377 39.971965918733 2498.248809498859 1.7128782123572832e-10 2.7513573009094237e-09 1606.2772478861607 -2.3256643662098247e-10 3.38714013129532e-09 -1456.418295136628 3.787001284451439e-09 1.35339653884573e-08 357.37947710830383 -4.399997564849655 71.9838242398399 -1635.996910882371 4.032802678659282e-11 2.3667579940295208e-09 5868.767164220284 -3.539231938518233e-11 4.300641954148708e-09 -12151.342519668982 +r_2770 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -2.702203604939605e-09 7.82839365427983e-09 -289.7040637489193 -5.237543874805311e-10 1.054394912824854e-08 -2013.147647119324 6.448948685855644e-11 4.504884264600441e-09 6985.45527968135 6.039123430161634e-10 4.121447205006787e-09 682.4578521483339 -5.595964786020789e-10 1.2617632955482426e-08 -2254.7734730215566 -3.2904590896384382e-09 1.3792857943688278e-08 -419.17731137036753 5.999996636861341 77.23461892719857 1287.2443703168606 1.0619770930213984e-10 3.785645917846247e-09 3564.7152304159613 -1.6029291350419035e-09 1.3991770542112556e-08 -872.8876552453945 +r_2771 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 2.2357324113643115e-10 4.788159639457689e-09 2141.651485266884 7.040669023473037e-10 4.2548426255627506e-09 604.3236248398324 -1.547432867059651e-10 4.8301196987413746e-09 -3121.375926258636 2.0311821023526263e-10 2.7535523637369113e-09 1355.640324197223 1.6326870817932727e-09 1.1881828394983676e-08 727.7468246966952 -1.49572852535183e-09 1.2283271986329564e-08 -821.2233555845472 -1.5999990729494418 59.98463023460742 -3749.041561882385 -1.1927950164892772e-09 1.15783889560622e-08 -970.69394120547 -2.3949309268405016e-10 5.813890992432642e-09 -2427.581909471846 +r_2772 MLCL (1-18:1, 2-16:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane -3.8757594394748174e-10 4.253777439270551e-09 -1097.533917081024 1.2267916671239667e-09 5.443939586087672e-09 443.7542030954767 -2.799999380970652 52.84615545679751 -1887.3631121474675 -3.1542544044977006e-11 3.0935543975837902e-09 -9807.561473711956 -4.092645625239711e-10 8.135859388424245e-09 -1987.9217829781485 6.687440010294917e-10 2.3124587048426463e-09 345.7913194410347 -2.001984913374233e-10 3.86944527874807e-09 -1932.80441470777 2.5896416877134073e-10 3.8282673205491355e-09 1478.3000052526206 4.742912597385747e-10 3.500075529893275e-09 737.9591038263043 +r_2773 MLCL (1-18:1, 2-16:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane -2.2797230426229406e-10 3.268467026420604e-09 -1433.712326151716 -4.2543001961371656e-10 3.3045973499503236e-09 -776.7663769827158 4.599998579353988 67.67386469917733 1471.1714260720764 4.708386652081159e-10 2.534146341954098e-09 538.219676762098 1.1671407355068227e-09 8.191340538807279e-09 701.8297185257823 4.0697255051582924e-10 2.421178058598647e-09 594.9241676201143 -5.00196769005894e-11 3.233759275908016e-09 -6464.974338668531 -3.176613346056942e-10 2.92621465187183e-09 -921.17432406562 -1.9455469085240315e-10 6.204944005676678e-09 -3189.305782600736 +r_2774 MLCL (1-18:1, 2-16:1, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 1.8101908789357981e-09 6.352498120632118e-09 350.9297386564403 -1.0089702050309879e-10 2.861157847110228e-09 -2835.720849677969 -6.058123314401617e-10 4.501980837045388e-09 -743.1312641561941 3.409479281395202e-10 2.3454002701561274e-09 687.9057112781046 3.5901759478363975e-10 8.077556776400619e-09 2249.9055460689933 7.004805895491397e-10 2.240625182394595e-09 319.86970314720065 6.784485435189141e-10 6.916467721515379e-09 1019.4535440582838 -8.960323385374229e-11 2.5255144029919607e-09 -2818.552740087831 3.335177531355613e-11 6.551794320708985e-09 19644.51444971792 +r_2775 MLCL (1-18:1, 2-16:1, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -3.5869569408760905e-10 2.055571421056841e-09 -573.068329210214 -4.685937400919632e-10 3.5335007651670717e-09 -754.0648674635751 -1.7999991971684206 42.392426522258845 -2355.135857224069 4.4778593607062814e-10 2.716059356403243e-09 606.5530731574486 -4.489869771612693e-10 4.655529980465699e-09 -1036.896439602858 7.425240335233632e-10 2.9712746028358903e-09 400.15871119172334 1.6367088327817028e-10 6.780956791504507e-09 4143.044050162415 9.415287171151624e-10 6.3143030824344625e-09 670.6437060976158 8.490699279146323e-11 2.352861558434825e-09 2771.104571108292 +r_2776 MLCL (1-18:1, 2-16:1, 4-18:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -2.8186311312646416e-10 2.1059861556573104e-09 -747.1662866053751 -5.993410097343163e-10 2.131215538972529e-09 -355.5931438626705 -7.40592975640504e-10 5.140640645993507e-09 -694.1249532575716 -7.707783713976112e-10 7.436774321175775e-09 -964.839517706117 -5.223216740571752e-11 2.098663158030147e-09 -4017.9515081742898 -7.901126707779577e-10 2.755974664808077e-09 -348.8078051063908 8.086482269774652e-11 3.6028319040589594e-09 4455.376001411008 -4.052782208727512e-10 2.4322365702406782e-09 -600.1399643442347 -2.750731273645878e-10 3.1069351892373993e-09 -1129.494261763855 +r_2777 MLCL (1-18:1, 2-16:1, 4-18:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 8.901291805977593e-11 2.7573760594948847e-09 3097.725722959886 5.830121757266988e-10 4.8748992759588045e-09 836.1573701068008 3.674253839643227e-10 2.406653002655617e-09 655.0045553981937 3.6366659801601406e-11 2.5662327672034883e-09 7056.553395895005 -2.9973031409230247e-10 3.044638350263599e-09 -1015.792599919005 -5.609864396958026e-10 2.542046692455536e-09 -453.13870578297264 -7.367336711966982e-10 6.6641807538220805e-09 -904.5576460483004 4.448924449764448e-11 2.536316240326414e-09 5700.964961229454 -3.8812489177197423e-10 2.7287238741596433e-09 -703.0530460702287 +r_2778 MLCL (1-18:1, 2-16:1, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -4.78713052658342e-10 2.208509098756061e-09 -461.3429875145426 -3.1171742446439217e-10 2.945486631547527e-09 -944.9220352723636 8.495151284744779e-11 3.040749786620377e-09 3579.3945095254785 8.58387699298118e-11 4.051319131734697e-09 4719.684514406903 -3.058804865923589e-10 2.2069800109153e-09 -721.5170982307544 -7.366225592753097e-10 2.4047284038282317e-09 -326.4532661332022 -1.951663253630276e-11 2.9497016129133766e-09 -15113.783627511844 -3.8626285626152376e-10 1.992661266315589e-09 -515.8821859294787 4.1706228686804524e-10 5.0943642810670065e-09 1221.4876390103373 +r_2779 MLCL (1-18:1, 2-16:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -1.8100237715672608e-10 2.198082152866982e-09 -1214.3940800090763 5.543769025259939e-11 3.439064711241873e-09 6203.477626091431 -2.082303129717184e-10 3.533978145509903e-09 -1697.1487460569122 -7.317168093962507e-10 7.601917980610312e-09 -1038.9153129996776 -8.6308598812864e-11 1.897869379855845e-09 -2198.9342961885445 -7.582506144709607e-10 2.388212501587724e-09 -314.9634772474275 1.4726918654979778e-10 4.825913348888792e-09 3276.9335269309386 -2.7319821200023427e-10 2.232921209093855e-09 -817.3264359035923 -4.5381390995991214e-10 2.9565558828025833e-09 -651.4908022682142 +r_2780 MLCL (1-16:0, 2-18:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane -7.207383991686749e-11 3.244950277473002e-09 -4502.258074796408 6.462686560613259e-11 2.1996770566179692e-09 3403.6573427897097 -3.838692469927691e-11 1.6002318821180291e-09 -4168.689976220399 -5.854303354869857e-10 5.9540600627775905e-09 -1017.0398938799016 -1.0241251418625012e-10 1.5483842715634303e-09 -1511.9092465081926 1.2646417486528462e-10 4.3530190752053815e-09 3442.096609448813 3.0000044185644748 54.69547956448225 1823.179966869997 1.3999989994228648 37.394085980691926 2671.008050441983 -8.822239443335683e-11 1.7572499852280094e-09 -1991.841183312516 +r_2781 MLCL (1-16:0, 2-18:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 3.199998219907484 56.48357748863595 1765.1127784148885 -5.843022891261466e-11 1.859373782492002e-09 -3182.212045194601 -9.814225687493946e-11 2.259519512257714e-09 -2302.290149223866 3.1226673149245857e-10 3.150479630969633e-09 1008.906589540333 6.645700391735686e-11 1.876686177882333e-09 2823.910298779195 1.87183461293784e-09 1.3215272028063992e-08 706.006392697411 -0.4000071705707029 19.997989355278364 -4999.4077173033165 -1.3999989991883917 37.39408598069884 -2671.0080508898195 4.8285998051605e-10 6.025000922522992e-09 1247.773923215557 +r_2782 MLCL (1-16:0, 2-18:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane -1.3999992133416654 37.39409158213093 -2671.0080424170224 7.546158548556869e-11 2.142154518152573e-09 2838.735105244032 -4.611014104223464e-10 1.7138500159918431e-09 -371.68613611960967 1.85649171322115e-10 3.511621606929642e-09 1891.53637580031 6.809003171103023e-11 2.1148390221264873e-09 3105.9451273304285 3.1070184311070513e-10 3.109916728176827e-09 1000.9328226188678 -1.9999974491455168 44.68102716582897 -2234.054207665044 -3.11689355823358e-11 1.7850005338327782e-09 -5726.857528122911 -6.004705459230857e-11 3.2174480829412955e-09 -5358.211330740974 +r_2783 MLCL (1-16:0, 2-18:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -1.7999990066668716 42.39242200223086 -2355.135855365307 8.170032036502857e-11 2.7420852083153077e-09 3356.272283956728 6.11540257646749e-10 3.2198311794699223e-09 526.5117282482865 2.546750183988634e-10 3.0099537435894717e-09 1181.8802497838185 1.236051955570326e-10 2.9248382911679993e-09 2366.274555035554 -2.077575878500105e-09 1.2886329719806909e-08 -620.2579579962262 -0.5999997988953377 24.48998881511225 -4081.666170588869 -5.4704770291482605e-11 3.747212794319988e-09 -6849.883062032377 -2.578450899167024e-12 3.8585422127431504e-09 -149645.75102010524 +r_2784 MLCL (1-16:0, 2-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -4.791831480507525e-10 3.857054246038326e-09 -804.922765278425 -2.565683936040807e-11 3.5543549088638802e-09 -13853.44024232667 -2.243485542427112e-11 6.931689825083774e-09 -30896.966768882023 7.370497268009449e-11 2.2447115569920083e-09 3045.536108852311 -3.1999985799742365 56.48358391252985 -1765.1127805495655 -7.218105083822607e-10 7.692487624467645e-09 -1065.7212017747202 5.826548234273726e-11 2.824006877748168e-09 4846.792241650735 -2.94330334834348e-10 1.981043218915199e-09 -673.0679731092447 1.9469830998307532e-10 2.1536362334539518e-09 1106.1401784335785 +r_2785 MLCL (1-16:0, 2-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -2.372118638746213e-10 2.7417255352013393e-09 -1155.8129894592803 -9.196659190920631e-10 6.160579511444505e-09 -669.8714591410015 -1.7073112940468414e-10 2.5957019077498277e-09 -1520.3448350635772 -6.703925589027659e-11 2.614588530221667e-09 -3900.085845972059 3.199998579020141 56.48358391250176 1765.1127810749647 4.6149932483426e-10 2.637794511688716e-09 571.5706112107613 7.200001043625337 84.55519246005271 1174.3775028326602 -0.5999196177633981 24.48666492739736 -4081.6576425168073 8.814387312166516e-11 2.554068323440078e-09 2897.612996781628 +r_2786 MLCL (1-16:0, 2-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 1.7416625222704054e-10 7.4124864609810964e-09 4255.9832150021175 5.873715506621405e-11 2.759045148441603e-09 4697.274059888237 -1.4888792333747618e-10 2.617063001874592e-09 -1757.740280884056 -1.3641138747333234e-10 3.2777859669367837e-09 -2402.868285155132 4.4891053009316794e-11 2.614308661361084e-09 5823.674175828543 1.4390172411498118e-10 3.282568999668027e-09 2281.1186035861324 -7.200001044359428 84.55519246000415 -1174.3775027122497 5.399915125866743 73.29218812109046 1357.2840760034408 2.1490367827731927e-10 2.866780125050769e-09 1333.9837400788338 +r_2787 MLCL (1-16:0, 2-18:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 8.710801856418309e-11 6.704637635100233e-09 7696.923596258946 5.259133021895745e-10 3.503838967032533e-09 666.2388938337815 -6.07799366731485e-10 3.171886577739278e-09 -521.8640807075013 -8.154829044796364e-11 2.6255986594129035e-09 -3219.685716266867 2.659087770296036e-10 4.082310096680508e-09 1535.2295408534128 -9.904883008471236e-11 7.13806222579511e-09 -7206.60932561265 6.886566929886261e-12 2.272116728387284e-09 32993.46033401305 -4.799995508528049 69.12239817695563 -1440.0513095095057 -6.872187788602222e-10 5.275890228563438e-09 -767.7162485742454 +r_2788 MLCL (1-16:0, 2-18:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 1.3806170113983443e-09 1.1630521797971333e-08 842.4147828072515 6.48918900939616e-10 2.902534887062229e-09 447.2877709155092 -2.999998724336314 54.69548013838401 -1823.183446535772 2.5963040945143737e-10 2.855728245176745e-09 1099.920556767791 -3.5320666500913e-10 3.888279310450002e-09 -1100.8510585012584 4.2816768924935327e-10 4.1291877394573296e-09 964.385646823668 1.999997631786179 44.6810211970524 2234.0537052110503 4.903379115067183e-10 2.002006842151456e-09 408.29126102031495 3.1999946682733027 56.4835148569583 1765.1127802483638 +r_2789 MLCL (1-16:0, 2-18:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 1.5999990875662085 39.971959593708974 2498.248899286008 3.4884755750086747e-10 3.4743036308814103e-09 995.9374965303492 2.999998725833308 54.69548013848693 1823.1834456294373 5.06705252008251e-10 3.1276992991958076e-09 617.2620644446916 1.8231250496592915e-09 7.0288139372340834e-09 385.5365784452164 -1.057583831008606e-09 9.651982257015552e-09 -912.6446503829924 4.199999091587578 64.67760874496304 1539.9433984285752 -5.061275834383171e-10 5.431949181903083e-09 -1073.237136178547 -3.1999946674192232 56.48351485688942 -1765.1127807173204 +r_2790 MLCL (1-16:0, 2-18:1, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 2.2830353948433103e-10 3.398072892073549e-09 1488.4013185904926 6.214273549407596e-10 2.407879244862714e-09 387.47557952164107 -2.452404374823894e-10 3.3597112113401087e-09 -1369.966244486645 4.4267122509383605e-10 3.113289427279529e-09 703.2960921775713 -2.0470537485104776e-10 4.3329157636695495e-09 -2116.6594999385634 1.321609863882167e-09 1.0289558347396749e-08 778.5624660194084 -6.199996722267678 78.50339732111229 -1266.184497149207 2.545294746587974e-10 2.108191337939408e-09 828.2700228590368 -4.520474747137777e-11 4.267577113644462e-09 -9440.550721683732 +r_2791 MLCL (1-16:0, 2-18:1, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -1.599999088790925 39.97195959305227 -2498.248897332684 6.042218445338961e-10 3.4662712899202987e-09 573.6752686580244 4.631724644075914e-10 5.119126655133113e-09 1105.2312148306569 4.924473710149101e-10 2.984707319196497e-09 606.0967110140438 -3.4163563778063067e-10 3.667802113027857e-09 -1073.6005578501758 2.3728973192719667e-10 3.136019192876604e-09 1321.599197490253 -1.8374853762308632e-10 2.504620417729373e-09 -1363.0695787451484 5.92848455465645e-10 3.7033643611694716e-09 624.6730217523656 9.159057099394538e-11 4.651475970940508e-09 5078.553305719642 +r_2792 MLCL (1-16:0, 2-18:1, 4-18:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -4.885951576438583e-10 3.837096603107301e-09 -785.3325075121181 -7.787897862469931e-10 2.1824088128903473e-09 -280.2307954509044 -4.1761015473432544e-09 1.3313155611699866e-08 -318.7938669779093 -1.2671064454993632e-11 2.9361603873553235e-09 -23172.16835084593 6.023442586029185e-10 5.464977440618645e-09 907.2847234062048 -3.3572837384419887e-10 2.129727204789807e-09 -634.3602062595243 -3.476087580763366e-10 4.1303553916788314e-09 -1188.219599107967 -1.198485146388003e-10 2.6218218122619787e-09 -2187.61310489632 1.2321635665035608e-10 2.760327493447809e-09 2240.228138931774 +r_2793 MLCL (1-16:0, 2-18:1, 4-18:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 3.0021231754009755e-10 6.370318864920078e-09 2121.93787287533 -4.2931841733995565e-10 2.3594240450593484e-09 -549.5743834327608 -7.026272076025416e-11 2.7991659081376683e-09 -3983.856414682259 3.6701193376640913e-09 1.4938732606337477e-08 407.0366991348429 -5.88906991015326e-10 3.307713347917712e-09 -561.6699068582853 2.441273961593572e-10 2.9375234632468e-09 1203.2748103901024 -7.70298307724245e-10 4.09044528660636e-09 -531.0209363812697 -1.7747523142650964e-10 2.87558771146683e-09 -1620.2755101956732 -7.164795309516568e-10 7.719637228684457e-09 -1077.4400237828042 +r_2794 MLCL (1-16:0, 2-18:1, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -4.398661514279065e-10 3.305148313864243e-09 -751.3986477784147 -8.524229296401366e-10 3.1278161468118003e-09 -366.93242732598185 3.298112485025024e-09 1.3792118183843608e-08 418.18216469166174 -5.312498463458766e-09 1.4428176485243384e-08 -271.5892829802297 -5.81678268695128e-10 3.369400365652879e-09 -579.2549845830434 -6.662026039789417e-10 2.6315551435154463e-09 -395.0082344017119 -2.3577607027302973e-10 2.367908815104404e-09 -1004.3041316119804 -8.435102326201455e-12 2.718652500498347e-09 -32230.22549535124 -3.82183284435662e-10 8.183994025050887e-09 -2141.379374332267 +r_2795 MLCL (1-16:0, 2-18:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -1.761000473980128e-10 3.565553765235236e-09 -2024.7318600525664 -4.14976925730377e-10 4.860961826950881e-09 -1171.3812324372932 -3.312091445008675e-10 4.11743715656441e-09 -1243.1532235528678 -1.26751247924628e-10 4.022432054484326e-09 -3173.485169058253 -1.5868499588275646e-10 3.7017141932657925e-09 -2332.7436678391346 -5.905104883161347e-10 2.2972544153232593e-09 -389.0285542385498 -2.8740130892893966e-10 6.932801693546363e-09 -2412.237341361763 -4.073543823277661e-10 5.4148292020223e-09 -1329.267447935643 2.3975347231949656e-10 3.608429914376873e-09 1505.0584583685456 +r_2796 MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 1.479711382525861e-09 8.388875825033314e-09 566.9264914833283 1.3347506758248051e-09 8.179701934984815e-09 612.8262066569243 6.418045291760621e-10 2.891135083907937e-09 450.4697228639892 1.8212375931810486e-10 3.721567520696101e-09 2043.4277958186976 -1.1744018493001608e-10 9.792113652110113e-09 -8337.958304429903 -1.6198402711401972e-11 3.047709054903684e-09 -18814.873967532723 -1.0217439891490148e-10 3.53375586116412e-09 -3458.553119658965 2.799998597287526 52.846151714281966 1887.363506734475 1.826201831851073e-10 1.560495152315521e-09 854.5031141129525 +r_2797 MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane -9.962331057999984e-11 4.070585392740821e-09 -4085.9768351826096 -6.267515951666336e-10 8.247089239982324e-09 -1315.846549666887 4.783031535340525e-10 2.485823981290213e-09 519.7172468805886 2.720401574894941e-10 3.775647373809722e-09 1387.9007454829652 6.602621081252544e-10 5.038147390731305e-09 763.0526314824579 -3.3541170896153476e-10 3.796654369823175e-09 -1131.9385305831936 7.874176505197583e-12 3.12996152788398e-09 39749.69986789039 -0.3999995997549951 19.997979501915307 -4999.49987804096 5.16511437511387e-10 7.71711968873381e-09 1494.084956940315 +r_2798 MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 3.3479098217556536e-10 5.3070250241105195e-09 1585.1756190157776 3.7486630756243007e-10 8.401891352212065e-09 2241.303414768162 1.7518644831765678e-10 2.474126595213206e-09 1412.2819538683702 9.89984623168126e-10 4.790522329396963e-09 483.89866037175847 5.11210378134212e-10 5.0110380154063695e-09 980.2301028581194 3.531235705650542e-09 1.2985133539260548e-08 367.7220843253894 1.678634701907306e-09 8.735239084471911e-09 520.37760654815 -2.399998996824829 48.935845228001895 -2038.994403445312 4.2026253656295076e-10 2.807710941141613e-09 668.0849937527202 +r_2799 MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -1.0045681870962856e-10 3.7399144447577445e-09 -3722.90750672486 -7.687158719080842e-11 2.749290992919912e-09 -3576.4722615856776 7.690344257883796e-10 2.687230100560518e-09 349.4291036198658 3.921213048193989e-10 3.090591174115448e-09 788.1722151105499 4.2486945890721296e-10 5.806168071723118e-09 1366.5769449884426 -2.1755906161434948e-09 1.2482356360846714e-08 -573.7456425958136 7.977929193919989e-10 8.869445624986638e-09 1111.747849522916 -2.2562561298315038e-10 2.7059166801520484e-09 -1199.2949933189211 -7.673519395166098e-11 7.379599275101974e-09 -9616.96829716847 +r_2800 MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane -6.028657448918636e-10 3.5138635622834662e-09 -582.8600467113537 -5.944699529607447e-10 2.471532869866105e-09 -415.75404401125553 -6.095950829291405e-11 2.393493415886898e-09 -3926.366013954738 3.830565368461416e-11 3.789580428070698e-09 9893.005505849964 -2.3078556393043782e-10 3.587082942973564e-09 -1554.2926004049211 -2.7238822912101405e-10 2.831068756902661e-09 -1039.3506232036557 -7.800000671005273 87.9812580079099 -1127.9647492206018 -6.331451942566446e-10 4.5797601839302936e-09 -723.3349041379431 1.9602822348634783e-10 2.692541824454196e-09 1373.5480414848098 +r_2801 MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane -3.220129933487128e-10 3.056726433255354e-09 -949.2556189945972 1.2276440702540223e-09 6.14051135049076e-09 500.1866175446255 4.279221906362164e-11 2.266306350130042e-09 5296.071107601583 9.044420474854616e-11 3.936698333441372e-09 4352.626400316324 -5.547102390020555e-10 3.392344353892789e-09 -611.5525035189082 -1.1738106356290898e-10 3.859859859485466e-09 -3288.3156297325763 -2.3254103357070246e-10 2.830465702166074e-09 -1217.189783112188 1.711691111773132e-10 5.484703953184913e-09 3204.2603454915047 -1.391057658034633e-09 6.498544998585336e-09 -467.1657541332152 +r_2802 MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane -5.081150675365316e-10 2.840244877188624e-09 -558.9767079647605 -6.062689587029918e-10 2.738016467397049e-09 -451.6174592303991 8.06497321925136e-11 2.889991657635677e-09 3583.386552031159 -2.0470031154550887e-09 8.101688708396706e-09 -395.7829202714986 -1.8278606772613128e-10 3.282103890865697e-09 -1795.5985003098156 -3.613866473016485e-10 3.508266309291645e-09 -970.7791739087978 7.80000066999143 87.9812580075025 1127.9647493619916 -4.1867841464364295e-11 2.347269430302283e-09 -5606.377945947262 2.2319977702681237e-10 4.225399248400529e-09 1893.1019128629969 +r_2803 MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -2.77896805399327e-10 4.1805589986770904e-09 -1504.3566235566432 -1.198425934553407e-11 2.636490330028418e-09 -21999.610105324577 -4.974462173161131e-10 2.8168156046507982e-09 -566.2553069251283 1.4855394582824268e-10 5.345916556973328e-09 3598.6365270662345 3.35409117492856e-10 4.090670981080951e-09 1219.6063755386972 2.1536389206703422e-10 7.073209636033936e-09 3284.306189002345 -1.6115934752963907e-10 5.433861345735634e-09 -3371.7320335615545 2.066650349469476e-10 2.779625862962565e-09 1344.9908755373715 1.7138650227420264e-10 3.796607135640797e-09 2215.231121040428 +r_2804 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 3.8681609950164887e-10 4.7454259972236135e-09 1226.7912331822124 1.9468444548333026e-10 3.9710874274505745e-09 2039.7558816739647 3.000926682706042e-09 8.260698073495444e-09 275.2715726479022 4.229153802509063e-12 3.3097912553175827e-09 78261.31207037107 -5.832082215848361e-10 7.788156411840197e-09 -1335.3989404806932 1.701099978840247e-09 1.0490719083085398e-08 616.7020876831483 6.80494633685554e-10 9.93596956329553e-09 1460.109907036649 2.6372069360406317e-10 3.9977226920435984e-09 1515.8926807789965 1.6997446810529816e-10 2.4496480615660317e-09 1441.1858962538358 +r_2805 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 3.9625902753218383e-10 3.533725679307668e-09 891.7716528289471 -1.7431278700655239e-10 3.53042295442996e-09 -2025.337908398684 -1.3197951340535458e-10 4.399343067273442e-09 -3333.3529983259928 -1.3422726357060711e-11 4.934291691925509e-09 -36760.72625387271 4.3090865234831395e-10 3.765581859666662e-09 873.8700973269969 -1.7582906880780802e-10 5.2313319535274494e-09 -2975.237251154196 4.5774018895403925e-10 3.672617808563294e-09 802.3367615929512 -8.459310570836698e-11 3.319977838320862e-09 -3924.643516182535 2.1897902147879067e-10 2.9310721579457122e-09 1338.5173329170268 +r_2806 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 8.396296289427101e-10 4.842506695739418e-09 576.7431887601758 7.268206947085623e-10 7.08647254477305e-09 974.9959785631246 -5.442656122248497e-10 4.390954285716043e-09 -806.7668041283544 5.015966820220979e-09 1.5460033059153957e-08 308.21641396888 5.541269928196625e-10 4.807777162256578e-09 867.6309265845924 7.025476423737349e-11 6.069921826433073e-09 8639.872174254697 3.184596354949155e-10 3.066615066408429e-09 962.9525141051636 -3.9999959088701953 63.12517798850088 -1578.1310637972797 6.180328246779006e-10 8.760437287690574e-09 1417.4711985979452 +r_2807 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane -2.4046478216995377e-10 8.157999532080237e-09 -3392.596395389988 5.30496796743475e-10 9.85078022402742e-09 1856.897211160885 -2.965074591679802e-11 3.908551194448319e-09 -13181.965827827657 -3.823182388361425e-09 1.5501128743984446e-08 -405.4509350946258 6.976754042890374e-10 4.991826135832847e-09 715.4940686091325 -5.8207017403224966e-11 5.262594240736305e-09 -9041.168016357991 5.809172703249311e-10 1.0537753105343197e-08 1813.9851651249749 3.999995910507928 63.12517798863176 1578.131063154412 4.1636573920448125e-11 8.325138110664464e-09 19994.77220813288 +r_2808 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane 6.180993603530413e-10 1.5276151986860613e-08 2471.4718970321032 3.000015004835166 54.69547653176458 1823.173432253209 -2.0172223537107915e-09 8.396693954536963e-09 -416.2502928391004 8.195449899078481e-11 1.1187474743582456e-08 13650.836600002163 2.475485933873763e-10 2.656330385802273e-09 1073.0541222044096 -1.884732416697257e-09 9.200030680852625e-09 -488.1345807684706 1.9935296639249558e-10 3.4631799832581262e-09 1737.210158408003 -6.325943760027601e-10 3.563044384327066e-09 -563.2431332762148 8.867369910434834e-11 2.117581815578625e-09 2388.060763188331 +r_2809 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 1.3999991939342882 37.39409132311799 2671.008060942724 -3.000015005885701 54.69547653178199 -1823.173431615357 2.865552528742298e-10 2.9725931474260502e-09 1037.3542685433629 9.754999370084044e-11 3.2652972005441502e-09 3347.3064186533293 1.3124714321557423e-10 3.886666296527569e-09 2961.3340155859214 1.397192689564003e-09 1.0392832742684432e-08 743.8367535352291 -4.715148262489525e-10 8.072408941839913e-09 -1712.0159308792986 -6.327860392825139e-10 4.201153203260717e-09 -663.9136994906218 -2.3092818727752465e-11 2.4686712740702543e-09 -10690.211979637885 +r_2810 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 2.2844085196307896e-09 1.484658330387565e-08 649.9092949572427 -1.1897239234804052e-10 2.595436717282923e-09 -2181.5453703664807 2.5341236294655235e-10 4.388985768886438e-09 1731.9540837919285 -1.1624597103826026e-09 1.1756764245698954e-08 -1011.3696105501522 -1.0111752012024234e-09 9.109632246411649e-09 -900.8955357666078 -3.5273745836032565e-10 4.311615848276589e-09 -1222.3300208372598 -6.785809801231953e-10 9.24395308114696e-09 -1362.247594895562 -4.6035335901059106e-10 3.812759796642801e-09 -828.2246066016178 -4.399998146368078 66.19299238533414 -1504.3868243438303 +r_2811 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane -1.3999991979825246 37.394091322352885 -2671.0080531645885 3.0698968384092075e-10 2.957708883401548e-09 963.4554641693449 -5.1195079537213397e-11 5.297362786740854e-09 -10347.40610743701 1.9623694728442612e-10 1.0510900145401466e-08 5356.228931836648 -9.283233976976071e-11 9.42065807333422e-09 -10148.034722273493 -2.947185125338262e-10 5.439823355704801e-09 -1845.769140505026 -3.36087819737013e-10 9.048678434707146e-09 -2692.3553616991203 -2.868959736304057e-10 5.739263361330838e-09 -2000.46842369578 4.399998145696249 66.19299238531272 1504.3868245730464 +r_2812 lysoPC acyltransferase (1-16:0, 2-16:1), mitochondrial membrane 3.4707391634575807e-10 2.388566693874965e-09 688.2011529484843 1.2876079111773319e-10 1.6186097370531795e-09 1257.0672508319665 1.7227894264434596e-10 1.3297073042212951e-09 771.8339129619304 2.4353680581902937e-10 1.4931670783444763e-09 613.1176243865328 2.5399038153283077e-10 1.4293770700274314e-09 562.7681888586284 2.733859542976872e-10 1.2208361758620284e-09 446.5614113198634 1.9473085566344692e-10 1.1377758550885751e-09 584.2812384365997 1.5040129711701086e-10 1.1247816622804535e-09 747.8536979673673 3.0375957024829717e-10 1.0164866051139391e-09 334.63525257263467 +r_2813 lysoPC acyltransferase (1-16:0, 2-18:1), mitochondrial membrane 2.7843920697746304e-10 1.8527408380880086e-09 665.4022823150657 2.00529512120218e-10 1.876626356306264e-09 935.8354969622732 1.9621760395576412e-10 1.6901956057638061e-09 861.3883625573417 1.783239208167106e-10 1.6276219894062923e-09 912.7334021997168 1.55979558226685e-10 1.334046448835574e-09 855.2700520518243 2.1835642472747827e-10 1.3910539315599787e-09 637.056561672548 1.3639646370445588e-10 2.220961695074428e-09 1628.3132529643965 2.771929234346854e-10 1.477580214792837e-09 533.0512036469781 2.5612402480314056e-10 1.3067930242949844e-09 510.2188384316536 +r_2814 lysoPC acyltransferase (1-16:1, 2-16:1), mitochondrial membrane 1.9519471554241047e-10 1.1438409999452594e-09 585.9999830255315 1.8705518727631686e-10 2.627853936829022e-09 1404.854885391214 1.2018540869033856e-10 1.6756247431406272e-09 1394.1998129389624 2.4747817434045994e-10 1.5095098634330767e-09 609.9567638463416 1.3064522878949638e-10 1.5360987097485712e-09 1175.77865183552 3.761464090888695e-10 1.598729549030066e-09 425.028528891883 1.8749133572853332e-10 2.0348526787257587e-09 1085.3049133278346 2.7094679002295835e-10 1.686072477266956e-09 622.2891502512684 2.2390975621536952e-10 1.250715001761421e-09 558.5799488604731 +r_2815 lysoPC acyltransferase (1-16:1, 2-18:1), mitochondrial membrane 1.7234664176928583e-10 2.5441365342376474e-09 1476.1741268178523 1.5451608664101478e-10 2.1667133215165924e-09 1402.2574403857957 6.618993362334365e-11 2.3876165661377443e-09 3607.2200641937 2.3261514799132387e-10 1.449397365359318e-09 623.088125547773 2.5749330025661663e-10 1.4136809092299095e-09 549.0165793910139 1.4716311771273156e-10 1.168860769157964e-09 794.2620320395961 2.3999553638952236e-10 1.906204519552013e-09 794.2666552173565 3.112170909772408e-10 1.516602065172106e-09 487.313232191035 2.2590143747612647e-10 1.9425304614303763e-09 859.9017709374534 +r_2816 lysoPC acyltransferase (1-18:0, 2-16:1), mitochondrial membrane 8.020161512037914e-11 1.8424598594975594e-09 2297.2852313910475 8.855574550541149e-11 2.058695860039831e-09 2324.745670978545 2.9875643961427097e-10 1.782868415899872e-09 596.7631754487907 2.6740115362776703e-10 1.9552396970964024e-09 731.2009206281039 6.995944942672355e-11 1.4078701430838764e-09 2012.40883772034 -2.0187563547239415e-11 1.742397099790732e-09 -8631.042055736336 1.6567430960313883e-10 2.2777580572260468e-09 1374.8408324031986 2.0199468753837308e-10 1.470700244482904e-09 728.0885761926359 3.0558219815792665e-10 1.556749231649687e-09 509.4371468737029 +r_2817 lysoPC acyltransferase (1-18:0, 2-18:1), mitochondrial membrane 1.8207525484140754e-10 1.797684505526684e-09 987.3304898529544 2.3355314757664376e-10 1.775516719885288e-09 760.2195638586404 -1.1456627594090376e-10 2.616207174251106e-09 -2283.575295404219 1.7291921428278212e-10 1.7250264973758635e-09 997.59098752025 1.203906784002393e-10 1.589490092685365e-09 1320.2767139504758 2.3980873290747616e-10 1.8279698726317118e-09 762.2615950925297 7.561514818628124e-11 1.838011635562474e-09 2430.7452668537417 1.3640887716702469e-10 1.4787554167983652e-09 1084.0609845264803 1.9559448420014358e-10 1.442992907574055e-09 737.7472393840624 +r_2818 lysoPC acyltransferase (1-18:1, 2-16:1), mitochondrial membrane 2.5289106631938837e-10 1.7277934560956601e-09 683.2164857549956 2.1693592539791166e-10 1.529602045834773e-09 705.0939317815255 1.7213780223122236e-10 1.6003807663344012e-09 929.7090735390628 1.4229516496653756e-10 1.2187221571010883e-09 856.4747490806772 1.7607785473205328e-10 1.7949837546088451e-09 1019.4261835711052 3.321730264553801e-10 1.537603259893066e-09 462.8922692190986 1.4453952462480804e-10 1.542134531285107e-09 1066.9292951447983 2.0552812556214423e-10 1.61686491508888e-09 786.6879098257522 2.3692845845822524e-10 1.9229028071961468e-09 811.5963863982973 +r_2819 lysoPC acyltransferase (1-18:1, 2-18:1), mitochondrial membrane 2.1374305621184807e-10 2.1296680843426278e-09 996.3683134725278 -3.6521190085610894e-10 2.966579095190207e-09 -812.2898208508869 2.1618380534173477e-10 2.0050661463799404e-09 927.482122544014 1.2729977880852482e-10 2.3095499930072667e-09 1814.2608059681909 7.017725234449873e-11 1.554430594587582e-09 2215.0063484345515 1.704529675999889e-10 1.525786019372327e-09 895.1360840797863 5.976679217636383e-11 2.4196869443730073e-09 4048.547456307901 1.8977545991170566e-10 1.4906855056809232e-09 785.499614320247 2.474481705068856e-10 2.421677052294827e-09 978.6603179704816 +r_2820 phosphatidylinositol 4-kinase (1-16:0, 2-16:1), cell envelope 0.0003543409478346 0.0051026875848509 1440.0502160513538 0.00040165576176 0.0072000690534487 1792.5969795375518 0.000480755149824 0.0072906905693543 1516.5080544685688 0.0006189597889151 0.0100944439745628 1630.8723369986428 0.0014067176859356 0.0216579179071634 1539.6065695127747 0.0013217105163311 0.0188662994053558 1427.415396355161 0.0013816879764649 0.0261345038805957 1891.4910114120903 0.00342296526072 0.0499335124433816 1458.7794102496298 0.0030076437530269 0.0460160043958465 1529.9685792087355 +r_2821 phosphatidylinositol 4-kinase (1-16:1, 2-16:1), cell envelope 0.0002215845470484 0.0040356379582064 1821.2632658560085 0.000564572233917 0.0086871942448215 1538.72148202353 0.0004774255796073 0.0073362434709779 1536.6255568063348 0.0004477738768131 0.008575147580027 1915.062048964769 0.0007709752680827 0.0155111388398305 2011.885397880896 0.0007682568112458 0.0144584449947652 1881.9807105019872 0.0019132501626293 0.0304421390255192 1591.1217267941142 0.0032669267372239 0.0493919625180764 1511.8784867531883 0.0021690142683874 0.0392050550461187 1807.505631360632 +r_2822 phosphatidylinositol 4-kinase (1-18:0, 2-16:1), cell envelope 0.0003116303729844 0.004750316560282 1524.343251522365 0.0006448956316143 0.0092868253172129 1440.0508953620802 0.0003234439499503 0.0060126258615088 1858.9390410398528 0.0005028658673231 0.0089731686467256 1784.405987722079 0.000994557220822 0.0181429274943293 1824.221584690052 0.0011213683305517 0.0173712253853398 1549.1096825243858 0.0020634764478299 0.0319655998952759 1549.1138718298705 0.0022910133921251 0.041769401092657 1823.1845015062013 0.0025464618845843 0.0425304335857341 1670.1775056286212 +r_2823 phosphatidylinositol 4-kinase (1-18:1, 2-16:1), cell envelope 0.0002583378677089 0.0043284499059637 1675.499586781616 0.0003490224578572 0.0068366620836198 1958.802916463581 0.000408505644438 0.0067968412954893 1663.8304483747493 0.0004360916819835 0.0085421842423437 1958.8046723318207 0.0011878739907565 0.0196619101802796 1655.2185108250983 0.0009848969931355 0.0163870166294529 1663.830506506373 0.0021385060651949 0.0325959711209066 1524.2402933253077 0.0021388989651463 0.0403688003745034 1887.363593714294 0.0022741538463029 0.0404591406408003 1779.085469814365 +r_2824 phosphatidylinositol 4-kinase (1-16:0, 2-18:1), cell envelope 0.0003468850033073 0.0050216415250442 1447.6386921213918 0.0005574105216819 0.0084391772583608 1513.996763623482 0.0004652225068148 0.0071878834600937 1545.0420722992085 0.0007879528110622 0.0114066494812172 1447.6310409806913 0.0012701397125781 0.0205675747632048 1619.315935052219 0.0004924874562294 0.0115987475387196 2355.135626706564 0.0016107108221761 0.028430864034366 1765.1128708476076 0.0018326950096637 0.0373685887482706 2038.9965897886327 0.002384226924846 0.0415229205218459 1741.567469486033 +r_2825 phosphatidylinositol 4-kinase (1-16:1, 2-18:1), cell envelope 0.0002647894261622 0.0043496043073282 1642.665407893902 0.0005994640660708 0.008873682546547 1480.2693019966248 0.0003289671500259 0.0060248912183934 1831.4567937612069 0.0005366464535844 0.0094724155609112 1765.1128592468383 0.0007365389219772 0.0156873528271344 2129.8742481959684 0.0008331530274319 0.014850608274972 1782.4586583746554 0.0015322551711766 0.0270750417355558 1767.0060604047042 0.0021370862089489 0.0403346685399682 1887.367405726027 0.0024211712677551 0.0417605557220419 1724.808000086718 +r_2826 phosphatidylinositol 4-kinase (1-18:0, 2-18:1), cell envelope 0.0002582997421184 0.0042646892305544 1651.0621325356713 0.0002687641049839 0.0060043108499189 2234.044925857316 0.0004369850033686 0.006997100301181 1601.222066487628 0.0004849312453488 0.0089166766166506 1838.7506893344373 0.0007868536116222 0.0160827689368994 2043.9340557567784 0.0007107621308907 0.0139225142600519 1958.814862942011 0.0021636410190634 0.0327357953270096 1512.99568822092 0.0026728474130929 0.0446291363352016 1669.7225631581523 0.0019809524120596 0.0377257116143292 1904.422912163964 +r_2827 phosphatidylinositol 4-kinase (1-18:1, 2-18:1), cell envelope 0.0002248454879965 0.0040428723808267 1798.0669378110822 0.0003488677848233 0.0066719672471334 1912.462983795219 0.0003857992452715 0.0065080107259382 1686.8904762520851 0.0005628590250437 0.0095683970855854 1699.9633407036806 0.0009538945214148 0.0177305226985431 1858.750868203369 0.0013121654245253 0.0186573198864854 1421.8725427272025 0.0013582117372371 0.0257515394820145 1895.98858381228 0.0025171800207685 0.0432645580875029 1718.7709154903118 0.0020172560779882 0.0372478885830356 1846.4630737502653 +r_2828 phosphatidylinositol 4-kinase (1-16:0, 2-16:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2829 phosphatidylinositol 4-kinase (1-16:1, 2-16:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2830 phosphatidylinositol 4-kinase (1-18:0, 2-16:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2831 phosphatidylinositol 4-kinase (1-18:1, 2-16:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2832 phosphatidylinositol 4-kinase (1-16:0, 2-18:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2833 phosphatidylinositol 4-kinase (1-16:1, 2-18:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2834 phosphatidylinositol 4-kinase (1-18:0, 2-18:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2835 phosphatidylinositol 4-kinase (1-18:1, 2-18:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_2836 phosphatidylinositol 4-kinase (1-16:0, 2-16:1), Golgi membrane 5.90574461004445e-05 0.0020873695542116 3534.473113959996 0.0001075054056379 0.0037997495351787 3534.4729994096538 9.083265322170474e-05 0.0032104524940406 3534.469576931285 0.0002681252022483 0.0066984480201347 2498.253787396611 0.0005348383291658 0.0133617419118252 2498.276803134837 0.0001639675033526 0.0066926157753554 4081.672062153343 0.0009060248041699 0.0213381150944442 2355.135863415198 0.0007639387440312 0.0241481973083273 3161.0122535345818 0.0010264909308436 0.0274177263100215 2671.014958455347 +r_2837 phosphatidylinositol 4-kinase (1-16:1, 2-16:1), Golgi membrane 5.9057622242119525e-05 0.0020873699108271 3534.4631760986067 4.192419902320583e-05 0.0021778445113651 5194.71942722069 4.541626528099719e-05 0.0022705862759833 4999.500205344675 6.709120299021777e-05 0.0033542124482951 4999.481748425665 0.0004018382621768 0.0115942597164716 2885.3050612112347 0.000164149203255 0.0067000226606502 4081.66626933886 0.0001001691594659 0.0070830296309051 7071.068249619134 0.0006109132595681 0.0215925690386785 3534.4737899355623 0.0007338878417474 0.023198284672246 3161.012262719819 +r_2838 phosphatidylinositol 4-kinase (1-18:0, 2-16:1), Golgi membrane 5.9057445063634907e-05 0.0020873695458645 3534.473161877147 0.0001343788022709 0.0042477305159289 3161.012335387128 6.812434567541815e-05 0.0027806084560723 4081.666294925925 0.0003354548620237 0.0074942435067456 2234.0542216420376 0.0003347077897177 0.0105801559016842 3161.0127480469832 5.4720878774434376e-05 0.0038693475285227 7071.062481420647 0.0005033471999079 0.0159108667905109 3161.0122780899387 0.0006111638136703 0.0216014193396059 3534.4728952256824 0.0010274430524223 0.0274430867342595 2671.008059235959 +r_2839 phosphatidylinositol 4-kinase (1-18:1, 2-16:1), Golgi membrane 4.4293076082925954e-05 0.0018078955562182 4081.666292116286 0.0001612581480165 0.0046527933054153 2885.307417109113 4.334354805537704e-05 0.0021694381575314 5005.21589686132 0.0001341819811683 0.0047426257974415 3534.472927100336 0.0001339477336433 0.0066967169410712 4999.499998187421 0.0004377665497588 0.0109364986909929 2498.249054665631 0.0003020082102839 0.0123269671002549 4081.6662198243343 0.0001527912339571 0.0108039719051428 7071.067904441743 0.0007336075998398 0.0231892815367946 3160.99254449633 +r_2840 phosphatidylinositol 4-kinase (1-16:0, 2-18:1), Golgi membrane 7.382182561842729e-05 0.002333517595074 3161.013122508859 5.37527198037464e-05 0.0026873673994525 4999.500321591643 0.0001135406711152 0.0035890346411769 3161.012354359751 0.0001338942731172 0.0047324840955399 3534.4932873979133 0.0005342491813324 0.0133472367237981 2498.316738737707 0.0002707344856515 0.0085598742891177 3161.7229214508698 0.0003020079891342 0.0123269580655166 4081.666217126473 0.0009149927238172 0.0264005951101395 2885.33388549782 0.00044033286774 0.0179729178305988 4081.666200128108 +r_2841 phosphatidylinositol 4-kinase (1-16:1, 2-18:1), Golgi membrane 4.427614060544536e-05 0.00180720466964 4081.66711219133 0.0001595613117877 0.0046050886964653 2886.093530360245 0.0002025941777815 0.0047718936611057 2355.3952602977747 0.0001677274237378 0.0053018845066136 3161.012307027943 0.0006027643974684 0.0141959205314064 2355.135869176765 0.000164141531016 0.0066997096107957 4081.666333513315 0.000100669503242 0.0071184060230453 7071.065013533355 0.0004583736526523 0.0187092824194051 4081.6661933214896 0.0010274433099692 0.0274430936454576 2671.0080623601016 +r_2842 phosphatidylinositol 4-kinase (1-18:0, 2-18:1), Golgi membrane 5.9057472003351017e-05 0.0020873705192656 3534.473197815116 0.000213911655418 0.0053445406425626 2498.480333910172 0.0001361718262332 0.0039289789336633 2885.309716662189 6.709105271075446e-05 0.0033542122871874 4999.4927067968965 0.000132821483641 0.0066406490283681 4999.679905937333 0.0003282809263134 0.0094719141451621 2885.307486953163 0.0005033470224972 0.0159108615022325 3161.012341603922 0.0007638968415095 0.024146873162786 3161.01230567576 0.001169093536427 0.0292087984899499 2498.4141627552026 +r_2843 phosphatidylinositol 4-kinase (1-18:1, 2-18:1), Golgi membrane 4.429349154797997e-05 0.0018078953592002 4081.6275620130673 0.0002150068966738 0.0053713780271207 2498.235224178765 8.917279568521728e-05 0.0031534272324251 3536.31083134016 0.0002226388065134 0.0059652095379746 2679.32155736524 0.0003342117532338 0.0105645566206355 3161.036833208817 0.0003283249052532 0.0094731800711792 2885.306572729279 0.0006040165578417 0.0174277343409931 2885.307383503656 0.0016790370435757 0.0357615444193515 2129.884183090547 0.000440332727021 0.0179729123483024 4081.6662594877785 +r_2844 phosphatidylinositol 4-kinase (1-16:0, 2-16:1), nucleus 0.0001107327184266 0.0020188609494999 1823.1837691552737 7.938550525484319e-05 0.0022913941759558 2886.413796322137 0.0001277491117034 0.0026676143554621 2088.166657200596 0.0002452047051007 0.004459300401864 1818.6031136846727 0.0004371795160067 0.0085225126231131 1949.4309113472784 0.0004897577667682 0.0081496133108097 1664.00899869043 0.0003469797064299 0.009267448648178 2670.8906822042254 0.0008397517614446 0.0178807181843937 2129.2861778145048 0.0008072764461718 0.0171939733133744 2129.8742698252977 +r_2845 phosphatidylinositol 4-kinase (1-16:1, 2-16:1), nucleus 8.135701334005722e-05 0.0017294943495867 2125.808554891029 0.0001886376363423 0.00355070107051 1882.286663127408 0.0001142440813713 0.0025326759287403 2216.89902736215 0.0001688190456844 0.00374719736322 2219.6532079824865 0.000438098073285 0.0085272705383469 1946.4295915311104 0.0004666538697786 0.0079590701524984 1705.561802428207 0.0005069277852526 0.0112430014306417 2217.870426068168 0.0010229971781246 0.0195222044593763 1908.3341456683063 0.0011872368279944 0.0207358995558987 1746.56808708731 +r_2846 phosphatidylinositol 4-kinase (1-18:0, 2-16:1), nucleus 8.608548599868548e-05 0.0017634259587731 2048.459084961309 0.0001343140852721 0.0030006558337938 2234.058943046866 0.0001353244012564 0.0027599665921908 2039.51879081996 0.000118817160205 0.0031338669161462 2637.5541300072086 0.0007675075241286 0.0112921267267616 1471.272446427458 0.0003260857113771 0.006650289522632 2039.4299077212409 0.0005511187988149 0.0117394129688977 2130.1057039136144 0.0013714524421447 0.0228078323238572 1663.0421604842006 0.0009536428281096 0.0186800280728595 1958.80758731102 +r_2847 phosphatidylinositol 4-kinase (1-18:1, 2-16:1), nucleus 5.517085517795265e-05 0.0014015118021573 2540.3119049665293 0.0002004066051579 0.0036544992438729 1823.5423133842 0.0001929776845842 0.0033042450725195 1712.2420551572595 0.0001795542176006 0.0038380775271999 2137.559105258844 0.0005663063437357 0.0096971745631414 1712.3549242219838 0.00051048444203 0.0082788539732507 1621.764208979313 0.0008024890438916 0.0140675836207889 1752.9938542921564 0.001526162029169 0.0240849807934137 1578.1404813568822 0.0017525791188114 0.0252402258695951 1440.1761152279446 +r_2848 phosphatidylinositol 4-kinase (1-16:0, 2-18:1), nucleus 0.00011007272994 0.0020072571491621 1823.573513853324 0.000189171421656 0.0035451087141935 1874.019174333552 0.0002156905157064 0.0034926620255318 1619.2932795828938 0.0001733703337101 0.0037524586668651 2164.417975417934 0.0004351411120626 0.0085235811434997 1958.808512276744 0.0004102480716159 0.0074795875549573 1823.186523582208 0.0010059023354821 0.0158745259333797 1578.137894050272 0.0011407517662133 0.0208004154365209 1823.395418055508 0.0013929248406534 0.0225556427630739 1619.300776665984 +r_2849 phosphatidylinositol 4-kinase (1-16:1, 2-18:1), nucleus 0.0001318345728603 0.0021669372741928 1643.679064738851 0.0001881350450018 0.0035507815713087 1887.3578664057384 0.0001917344191269 0.0032834477775173 1712.4978355309236 0.000307333129835 0.0050375126179916 1639.104974037405 0.0003311181666245 0.0074016393411914 2235.346799798074 0.0003554638334409 0.0069628585244694 1958.8092709930424 0.000955829016785 0.0154776713102242 1619.2928900906988 0.0012919814808583 0.0221251712975212 1712.499105081708 0.0008066640532027 0.0171809709530348 2129.879332644224 +r_2850 phosphatidylinositol 4-kinase (1-18:0, 2-18:1), nucleus 0.0001316490837656 0.002191169405721 1664.4015613672846 0.0002543895908371 0.0041196796399099 1619.437189372625 0.000179765072497 0.0031751740669075 1766.290872193348 0.0002342540624974 0.0044212987773561 1887.3947073618715 0.0003650351884499 0.0077770071443306 2130.481496141287 0.0004919854804754 0.0081858425275723 1663.838233531039 0.0006037389333248 0.0123102200506705 2038.9972173695533 0.000992869579338 0.0194484025664376 1958.8073772392768 0.000579539663088 0.0144865529438147 2499.6654873671523 +r_2851 phosphatidylinositol 4-kinase (1-18:1, 2-18:1), nucleus 0.0001535514377947 0.0023665761976541 1541.2269866317858 0.0002575217541782 0.0041273763732857 1602.7292088218242 0.0001007658496727 0.002374329851673 2356.284256405416 0.0003017766468084 0.0050210591008698 1663.832888983315 0.0004687071795737 0.0088462135419177 1887.3646334932064 0.0002462433295053 0.0057993738188688 2355.1394592166234 0.0005528635728096 0.0117753636896005 2129.885973452599 0.0005659733906074 0.0144515861025446 2553.4038070297074 0.0011673154589882 0.0206084784698208 1765.4592262217268 +r_2852 phosphatidylinositol 3-kinase (1-16:0, 2-16:1), vacuolar membrane 0.0002850253282445 0.0040295221193837 1413.741769617846 0.000647140957363 0.0083337911371574 1287.7860754039432 0.0004086289127551 0.0064088784370816 1568.3859455440886 0.0005192638031759 0.0087681285919486 1688.5691893638214 0.0012865857374954 0.0194924427125709 1515.0519817292966 0.0009574918986494 0.0145714460192299 1521.834914716643 0.0019110303583478 0.0283825578846977 1485.19659882513 0.0028030267608231 0.0404901232768787 1444.5143315359471 0.0030429976834572 0.0442859641126386 1455.34005344112 +r_2853 phosphatidylinositol 3-kinase (1-16:1, 2-16:1), vacuolar membrane 0.0003317842926749 0.0047360301697606 1427.4425505731583 0.0004707566058567 0.0075271479817727 1598.946863012781 0.0003407688889712 0.0055437813286817 1626.8449110531094 0.000837432767717 0.0110551389522888 1320.1225672630294 0.0011062270759963 0.0178375593728866 1612.4681595612255 0.0008202576317173 0.0136177053574094 1660.174173436062 0.0029688598160298 0.0351715288434116 1184.6813599452755 0.002101669901045 0.0370510822756982 1762.935380921328 0.0024156783465269 0.0389652223596821 1613.0136868471486 +r_2854 phosphatidylinositol 3-kinase (1-18:0, 2-16:1), vacuolar membrane 0.0002745438809983 0.0040576708542993 1477.968053610862 0.000695860470016 0.0089488846915196 1286.0171079000056 0.0004306594280809 0.0064964288107494 1508.484056577502 0.0007791604454912 0.0103227436136442 1324.8546783116244 0.0015088085377685 0.0201055964466113 1332.547897452012 0.0009565956823692 0.0155521742329638 1625.783444312044 0.0014571889356302 0.0253530515391519 1739.860282989749 0.0024415050300358 0.0417191888451935 1708.7488386039126 0.0028573456734079 0.0435567337158251 1524.377471063022 +r_2855 phosphatidylinositol 3-kinase (1-18:1, 2-16:1), vacuolar membrane 0.0003687043371244 0.004694508542417 1273.2447301895563 0.0004563760717055 0.0069583701857516 1524.700924776313 0.000379730803725 0.0061601118666238 1622.2312770509209 0.0006509657058861 0.0096359412982631 1480.2532930894474 0.0012377776631223 0.0190321410218274 1537.6057905115572 0.0010977619771159 0.0168164677437939 1531.8865195143649 0.002085689409642 0.0299271176822354 1434.8789203169056 0.0033197410842441 0.047337261501181 1425.932333272877 0.0039357277569539 0.048344347283027 1228.3458173042736 +r_2856 phosphatidylinositol 3-kinase (1-16:0, 2-18:1), vacuolar membrane 0.0002430142702053 0.0038551887383118 1586.4042613855102 0.0005238294465723 0.0078450033166436 1497.6254901242648 0.0004477989558638 0.0067543358214601 1508.341127868576 0.000828685969822 0.0109087884722409 1316.395941225346 0.001137721289581 0.0179141594643827 1574.5648454007644 0.0009575685484367 0.0150805871161294 1574.8832959007505 0.0019624560537986 0.0290598391989606 1480.7892967952694 0.0027445774021951 0.0423651746217866 1543.5955490962706 0.0026407538295888 0.0400967414692178 1518.3824035374537 +r_2857 phosphatidylinositol 3-kinase (1-16:1, 2-18:1), vacuolar membrane 0.0002503633210923 0.0040304741667922 1609.8500967343682 0.0004966588535564 0.0077535862445619 1561.1493058143128 0.0004031349053629 0.006363400072866 1578.4790620243537 0.0005280075179386 0.0087977235134023 1666.2117895119138 0.0014227955587544 0.0206269889295448 1449.7507250867386 0.0016147217692149 0.0188827906617608 1169.4145097790488 0.0020621951431641 0.0307376401163577 1490.5301381514696 0.0037425351524956 0.0472520179436708 1262.5671107501057 0.002788287405443 0.0433262328020133 1553.8653840861546 +r_2858 phosphatidylinositol 3-kinase (1-18:0, 2-18:1), vacuolar membrane 0.0002657023338002 0.0041669500241059 1568.277539947522 0.0004767528726466 0.0074180652927004 1555.9560766817783 0.0003744877499273 0.0058296266444919 1556.6935488872564 0.0003809271672136 0.0069791378323649 1832.14494345858 0.0013342961441226 0.0193991147419196 1453.8837444272708 0.0010214474571057 0.0145600805085551 1425.4360718476105 0.0012576140836855 0.0243593402028571 1936.948744361296 0.0029395792014637 0.0438555709049929 1491.8996189371503 0.0023481985500269 0.0373463078301598 1590.423766752229 +r_2859 phosphatidylinositol 3-kinase (1-18:1, 2-18:1), vacuolar membrane 0.0002478997399984 0.0041461901995945 1672.5270464669095 0.00062459932543 0.008487098011999 1358.8067848384153 0.0004459445375543 0.0060070556407848 1347.0409736888807 0.0005612594502063 0.0092584487199307 1649.5844687384106 0.0015066219643805 0.0215174348317999 1428.1907034752994 0.0009153670555709 0.014599295951079 1594.911665459966 0.0016848691755353 0.0259042543718367 1537.463842770248 0.00305649290811 0.0457162988835837 1495.7109425080014 0.003880659440881 0.0497742072180636 1282.6223990107032 +r_2860 PI 4-P 5-kinase (1-16:0, 2-16:1), nucleus 0.0001107327184266 0.0020188609494999 1823.1837691552737 7.938550525484319e-05 0.0022913941759558 2886.413796322137 0.0001277491117034 0.0026676143554621 2088.166657200596 0.0002452047051007 0.004459300401864 1818.6031136846727 0.0004371795160067 0.0085225126231131 1949.4309113472784 0.0004897577667682 0.0081496133108097 1664.00899869043 0.0003469797064299 0.009267448648178 2670.8906822042254 0.0008397517614446 0.0178807181843937 2129.2861778145048 0.0008072764461718 0.0171939733133744 2129.8742698252977 +r_2861 PI 4-P 5-kinase (1-16:1, 2-16:1), nucleus 8.135701334005722e-05 0.0017294943495867 2125.808554891029 0.0001886376363423 0.00355070107051 1882.286663127408 0.0001142440813713 0.0025326759287403 2216.8990273621503 0.0001688190456844 0.00374719736322 2219.6532079824865 0.000438098073285 0.0085272705383469 1946.4295915311104 0.0004666538697786 0.0079590701524984 1705.561802428207 0.0005069277852526 0.0112430014306417 2217.870426068168 0.0010229971781246 0.0195222044593763 1908.3341456683072 0.0011872368279944 0.0207358995558987 1746.56808708731 +r_2862 PI 4-P 5-kinase (1-18:0, 2-16:1), nucleus 8.608548599868548e-05 0.0017634259587731 2048.4590849613087 0.0001343140852721 0.0030006558337938 2234.058943046866 0.0001353244012564 0.0027599665921908 2039.51879081996 0.000118817160205 0.0031338669161462 2637.5541300072086 0.0007675075241286 0.0112921267267616 1471.2724464274577 0.0003260857113771 0.006650289522632 2039.4299077212409 0.0005511187988149 0.0117394129688977 2130.1057039136144 0.0013714524421447 0.0228078323238572 1663.0421604842006 0.0009536428281096 0.0186800280728595 1958.80758731102 +r_2863 PI 4-P 5-kinase (1-18:1, 2-16:1), nucleus 5.517085517795265e-05 0.0014015118021573 2540.3119049665293 0.0002004066051579 0.0036544992438729 1823.5423133842 0.0001929776845842 0.0033042450725195 1712.2420551572595 0.0001795542176006 0.0038380775271999 2137.559105258844 0.0005663063437357 0.0096971745631414 1712.3549242219838 0.00051048444203 0.0082788539732507 1621.764208979313 0.0008024890438916 0.0140675836207889 1752.9938542921564 0.001526162029169 0.0240849807934137 1578.1404813568822 0.0017525791188114 0.0252402258695951 1440.1761152279446 +r_2864 PI 4-P 5-kinase (1-16:0, 2-18:1), nucleus 0.00011007272994 0.0020072571491621 1823.573513853324 0.000189171421656 0.0035451087141935 1874.019174333552 0.0002156905157064 0.0034926620255318 1619.2932795828938 0.0001733703337101 0.0037524586668651 2164.417975417934 0.0004351411120626 0.0085235811434997 1958.808512276744 0.0004102480716159 0.0074795875549573 1823.186523582208 0.0010059023354821 0.0158745259333797 1578.1378940502714 0.0011407517662133 0.0208004154365209 1823.395418055508 0.0013929248406534 0.0225556427630739 1619.300776665984 +r_2865 PI 4-P 5-kinase (1-16:1, 2-18:1), nucleus 0.0001318345728603 0.0021669372741928 1643.679064738851 0.0001881350450018 0.0035507815713087 1887.3578664057384 0.0001917344191269 0.0032834477775173 1712.4978355309236 0.000307333129835 0.0050375126179916 1639.104974037405 0.0003311181666245 0.0074016393411914 2235.346799798074 0.0003554638334409 0.0069628585244694 1958.8092709930424 0.000955829016785 0.0154776713102242 1619.2928900906988 0.0012919814808583 0.0221251712975212 1712.499105081708 0.0008066640532027 0.0171809709530348 2129.879332644224 +r_2866 PI 4-P 5-kinase (1-18:0, 2-18:1), nucleus 0.0001316490837656 0.002191169405721 1664.4015613672846 0.0002543895908371 0.0041196796399099 1619.437189372625 0.000179765072497 0.0031751740669075 1766.290872193348 0.0002342540624974 0.0044212987773561 1887.394707361872 0.0003650351884499 0.0077770071443306 2130.481496141287 0.0004919854804754 0.0081858425275723 1663.838233531039 0.0006037389333248 0.0123102200506705 2038.9972173695533 0.000992869579338 0.0194484025664376 1958.8073772392768 0.000579539663088 0.0144865529438147 2499.6654873671523 +r_2867 PI 4-P 5-kinase (1-18:1, 2-18:1), nucleus 0.0001535514377947 0.0023665761976541 1541.2269866317858 0.0002575217541782 0.0041273763732857 1602.7292088218242 0.0001007658496727 0.002374329851673 2356.284256405416 0.0003017766468084 0.0050210591008698 1663.832888983315 0.0004687071795737 0.0088462135419177 1887.3646334932064 0.0002462433295053 0.0057993738188688 2355.1394592166234 0.0005528635728096 0.0117753636896005 2129.8859734525995 0.0005659733906074 0.0144515861025446 2553.4038070297074 0.0011673154589882 0.0206084784698208 1765.4592262217268 +r_2868 PI 4-P 5-kinase (1-16:0, 2-16:1), cell envelope 0.000235426037608 0.0041557522679114 1765.2050343002284 0.0003398308349936 0.0065522170999592 1928.081982343074 0.000431221310729 0.0068910033196287 1598.0201228872188 0.0004023261730799 0.0082034220494854 2038.997857555534 0.0015397730609667 0.0226527339839908 1471.1735487675646 0.0013502743629004 0.0190043283845623 1407.441991547526 0.0017109900477536 0.0292962488178022 1712.2395806021746 0.0031885352354668 0.0483847688162144 1517.4606909786903 0.0032278383905739 0.0480071413677412 1487.284540264891 +r_2869 PI 4-P 5-kinase (1-16:1, 2-16:1), cell envelope 0.0001626006200203 0.0034582191831723 2126.817956007777 0.0004842173972586 0.0080490885838656 1662.2881849010969 0.0005685357267804 0.0080064419498203 1408.2566095115146 0.0005040569368702 0.0091739423455648 1820.0210481235056 0.0012712619514416 0.0202973450473535 1596.6296343830536 0.0012296373637802 0.0181820026088226 1478.6475382405624 0.002180494631013 0.0323191886940306 1482.1952888283356 0.0027723653403699 0.0457724098875386 1651.0237385030357 0.0031217105234313 0.0472346497347112 1513.101531361464 +r_2870 PI 4-P 5-kinase (1-18:0, 2-16:1), cell envelope 0.0002835561391105 0.0045397403063802 1601.002299093209 0.0006179953462142 0.0090917747723624 1471.1720449121442 0.0006859416071919 0.0087638685047451 1277.640605681057 0.0006683017883424 0.0103981889444566 1555.9121830643824 0.0010692195649267 0.0188732368691238 1765.1413692955612 0.001203435486699 0.0181043400931759 1504.3880867128803 0.0024660922059878 0.0349662781625355 1417.882027185947 0.0036665125422722 0.0522474428821938 1424.990158353986 0.0025654730114565 0.0428343015200761 1669.6453764585358 +r_2871 PI 4-P 5-kinase (1-18:1, 2-16:1), cell envelope 0.000271651844194 0.0044282179293508 1630.1078104179742 0.0006851951906874 0.009523800943593 1389.9398409434066 0.0003295731296102 0.0060361877765204 1831.5169636732635 0.0005904879788211 0.0098668258519878 1670.9613414460769 0.001579473808197 0.0226646516373214 1434.9495078486327 0.0009199808859706 0.0157663585817883 1713.7702339493785 0.0023389126105083 0.0340885900317639 1457.4546256499807 0.002444544199663 0.0431489641800452 1765.1128658664811 0.0018241686409533 0.0360810628072323 1977.9455691319563 +r_2872 PI 4-P 5-kinase (1-16:0, 2-18:1), cell envelope 0.0002949259196413 0.0045968498791254 1558.645603178979 0.0005064691266731 0.0080064256561866 1580.8319272643646 0.0004309156484176 0.0068649966796166 1593.118445530117 0.000832753470034 0.0116773685841126 1402.2599730068057 0.0011385547874586 0.0194947806380004 1712.2391344481791 0.0007096456141411 0.0139010684524997 1958.8747080925707 0.0019106562800827 0.0309393125853267 1619.3029017227054 0.0021390592144351 0.0403718250751723 1887.363603715544 0.003410931173878 0.0497121741140723 1457.4370334641585 +r_2873 PI 4-P 5-kinase (1-16:1, 2-18:1), cell envelope 0.0003527278487529 0.005031275199783 1426.390124162361 0.0005897772533792 0.0087723064281773 1487.39314341393 0.0004877149730387 0.0073603072539621 1509.141129726429 0.0008386371665714 0.011831616527577 1410.8147121534912 0.0013059665336158 0.020738703691613 1587.9965648272214 0.0012057988851865 0.0177685082057237 1473.5880439111795 0.0021387655815153 0.0325999558257578 1524.241651703587 0.0029669711938688 0.0471173037386365 1588.060707700925 0.0023682576380795 0.0409985294051623 1731.1684652016606 +r_2874 PI 4-P 5-kinase (1-18:0, 2-18:1), cell envelope 0.0003541520239799 0.0050468223121297 1425.0440405264465 0.0002687634106707 0.0060043232563966 2234.0553133370745 0.0003645592341167 0.0063232982310693 1734.5050239611644 0.0006203690710376 0.0101134288778427 1630.2277708536303 0.0016097471702177 0.0229513368828302 1425.7727739769966 0.0013371881526016 0.0189847113535386 1419.7486955446204 0.0022640530128465 0.0334904775894254 1479.2267406900612 0.0036473892099664 0.051853611887815 1421.6637957398657 0.0037616548741003 0.0516507012400829 1373.0845324409306 +r_2875 PI 4-P 5-kinase (1-18:1, 2-18:1), cell envelope 0.0003135542228116 0.0047807898868994 1524.7091377145246 0.0005394240104099 0.0083121946985151 1540.938953050614 0.0003028661311985 0.0056394589058717 1862.030225550145 0.0007013455089717 0.010675550653423 1522.1528500374334 0.001020520413562 0.0183422999189977 1797.3476743081878 0.0010112229195169 0.0163201004664496 1613.897405949329 0.001456944573183 0.0266760313155177 1830.9571830339305 0.0030528505186633 0.0474304439896265 1553.6444938808706 0.003007793155739 0.0464628530745763 1544.7489461142552 +r_2876 PI 3-P 5-kinase (1-16:0, 2-16:1), vacuolar membrane 0.000153461619135 0.0025856897654216 1684.909738340583 0.0004482277979523 0.0065000451775544 1450.165564752585 0.0002382259786492 0.0046018960927851 1931.735622990181 0.0002012708567465 0.0047402088855415 2355.1392199366137 0.0007182253081223 0.0136171753889496 1895.947585660777 0.0006977239238172 0.0117843706714379 1688.973284299307 0.0009060251810667 0.017414643354284 1922.0926435820536 0.0018869745334558 0.0307296695291424 1628.515328866842 0.0009890949869987 0.0215084407361688 2174.557653095861 +r_2877 PI 3-P 5-kinase (1-16:1, 2-16:1), vacuolar membrane 6.655235527677388e-05 0.0017289818773194 2597.9274063690623 0.0002960889339801 0.0056942593859768 1923.1584610178568 0.0002726391475607 0.0047997560605261 1760.47941151127 0.0003700379042631 0.006698940338784 1810.3389576057627 0.0005038448643553 0.0108404867384952 2151.552492723312 0.0004384241071049 0.0090418387620686 2062.349815062696 0.0014205054894781 0.0214420951117147 1509.46935936108 0.0011689011450258 0.025539821103489 2184.9427740037054 0.0018290691231893 0.0330235318331996 1805.4829866471373 +r_2878 PI 3-P 5-kinase (1-18:0, 2-16:1), vacuolar membrane 0.000228762161592 0.0036062619118459 1576.4241283382892 0.0003219828353739 0.0055224860543908 1715.1492091114137 0.0001701431256456 0.0034929644670223 2052.956564520485 0.0005107967160201 0.0078666583474787 1540.076140029073 0.001041876185966 0.0153661537886168 1474.854113722634 0.0002955053596969 0.0077873139387393 2635.2530278051067 0.001054560062492 0.0210026294401025 1991.6010654217064 0.0009167471041422 0.024143419357315 2633.596468232641 0.0011008319792711 0.0248654791335155 2258.7896792369065 +r_2879 PI 3-P 5-kinase (1-18:1, 2-16:1), vacuolar membrane 0.0002211664209726 0.0033525330443413 1515.8417944269918 0.0004476109816363 0.0068192148750803 1523.4690735582112 0.0001689263832246 0.0038270750185325 2265.5283002439264 0.0003183123661091 0.0061495643554805 1931.927568711523 0.0004350364417619 0.0097474655523392 2240.608973551757 0.000549714886562 0.0115540145130058 2101.8194695918755 0.001081575331627 0.0198638557546202 1836.5670123724765 0.0014868056757948 0.0291460349941677 1960.31233056636 0.0021194820932935 0.0314628922097431 1484.461336535845 +r_2880 PI 3-P 5-kinase (1-16:0, 2-18:1), vacuolar membrane 0.0001473772900714 0.0027549674390118 1869.3296895855103 0.0002014451105123 0.0042970187329694 2133.096565134155 0.000266526672832 0.0050208289607107 1883.7998116137665 0.000466161417795 0.0076065401293241 1631.7395303333094 0.0007024714408216 0.0130520442423745 1858.0177760833835 0.0005198480279928 0.010406598478664 2001.853987759661 0.0008053263862597 0.0158977340317964 1974.0734071350785 0.0014498100593061 0.0280118689303704 1932.106123182599 0.0013201914830367 0.0253763591704327 1922.1726163587189 +r_2881 PI 3-P 5-kinase (1-16:1, 2-18:1), vacuolar membrane 0.0001476415295201 0.0029494222217995 1997.691456722784 0.0002149211919798 0.0046485874436949 2162.926513142937 0.0002219889167291 0.0044824242515571 2019.2108316045324 0.000377589464763 0.0072253860785053 1913.5560583080303 0.0004182783051822 0.0095343429915743 2279.4256535540217 0.0007410286972646 0.0107781688470317 1454.4873750257534 0.0006537413096979 0.0154921233363557 2369.763560377217 0.0024438264112171 0.0349178931337228 1428.8205157882592 0.0013941074786857 0.0288588770269608 2070.061130019013 +r_2882 PI 3-P 5-kinase (1-18:0, 2-18:1), vacuolar membrane 0.0001308085115502 0.0027073136656893 2069.676990896755 0.0002887943546887 0.0053870634717222 1865.3631500269955 0.0002043323501957 0.0037593080695938 1839.8007295430168 0.0002930608642473 0.0059446557556008 2028.471379441357 0.0012385294474852 0.0184496947669246 1489.6452243736337 0.0008851661538793 0.0132288536711777 1494.5051404417504 0.0010531642456603 0.0221225360438898 2100.577961609358 0.0016414625935828 0.0301435248190666 1836.3820739449025 0.0022016640759846 0.0358891360456285 1630.09136757514 +r_2883 PI 3-P 5-kinase (1-18:1, 2-18:1), vacuolar membrane 0.0001874866915083 0.0035590408755836 1898.2898716443472 0.0003694245164072 0.0061642852679936 1668.6183494107663 0.0003445779665944 0.0049090111755326 1424.644536634146 0.0003099838189155 0.0066181037827099 2134.983627810751 0.000602762137841 0.012516368901603 2076.502174876744 0.0005599435269631 0.0106172755686333 1896.133280835771 0.0011294686763914 0.0194798995562442 1724.695864827487 0.0023525837395397 0.0391220271054603 1662.9387701673686 0.0015405432246595 0.0278977629094859 1810.9042617516272 +r_2884 PE (1-16:0, 2-16:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane -3.600005036205032 79.92677845746637 -2220.185184566345 1.2255961571712243e-10 9.092938606267815e-10 741.9196407448811 0.7999722444682206 34.63523318769286 4329.5543598161385 -1.2000430101619588 34.62364469313991 -2885.2003136510143 1.6000119830256732 56.55149762724873 3534.4421308837987 0.1999997373093158 50.994806024914894 25497.43650215264 0.599888440576573 37.41382186874979 6236.79660051294 2.000034455521355 44.68095932777896 2234.009479408285 -1.4000097249403418 37.39397580512345 -2670.979718138523 +r_2885 PE (1-16:1, 2-16:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane -0.6000181779358645 46.904791261746965 -7817.228375164424 0.5999971801697883 42.426378020259975 7071.096235527987 2.378431927736324e-11 9.199161956433943e-10 3867.742376461143 1.3999868837854623 37.39366774255991 2671.001291201398 0.2000054219181799 14.142135547328907 7070.876085106483 1.8000020625294193 42.39234784823978 2355.127737390963 0.1999434771751168 42.43009860679843 21221.046670923304 1.6000010600343566 59.98457534073448 3749.033474980725 4.8671425937522745e-11 1.2715469255213003e-09 2612.512169159634 +r_2886 PE (1-18:0, 2-16:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane 2.400016733770292 63.20627128971242 2633.576274712839 1.2161327941641406e-10 1.1750474120439335e-09 966.2163685434984 2.000015083971966 44.681060299279125 2234.036165894508 -1.2000049352240227 34.62365065797281 -2885.292355194281 -0.2000513693121592 46.90782259233437 -23447.888786574425 -2.200069656553076 46.85714654955628 -2129.80286374064 -1.968901048780212e-14 9.765904085598322e-10 -4960078.665024113 -0.2001880764054465 50.99486070235773 -25473.475552598047 -2.0000169518467685 44.68099403247304 -2234.03076615004 +r_2887 PE (1-18:1, 2-16:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane 1.5999994981912709 39.97196473724871 2498.248579604885 0.9999681994507632 50.985447666231806 5098.706908303263 -2.2631955909005084e-11 1.5424587819374959e-09 -6815.4020277309 1.8000060997278649 42.39240354874315 2355.125549582986 -0.4000053183272867 40.001972619428415 -10000.360191885891 1.1999974308264745 48.97990344847062 4081.667359465652 -0.7999416627304147 28.273589038791528 -3534.456368016414 -2.800008938119188 59.94053215414374 -2140.726457623624 2.0989655367966776e-11 1.4137305358792715e-09 6735.368023416084 +r_2888 PE (1-16:0, 2-18:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane -2.4000095546392424 48.93583050242479 -2038.984820199209 0.3999818885236015 48.993020339276896 12248.809694888469 -0.1999934060049144 54.77732399305743 -27389.56502981472 1.0000233861623649 31.61008682297334 3160.9347601638083 -1.5999634805063054 44.69713868503265 -2793.634931647835 -0.6000296180611991 37.41547300595735 -6235.604356807136 0.1999412921910421 46.908395458716335 23461.0844736843 0.999995248683414 58.30661969604893 5830.689673057445 -0.7999974344851148 52.914181543374816 -6614.293904258685 +r_2889 PE (1-16:1, 2-18:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane 2.2000266888142503 46.85718099186135 2129.846025509626 -0.7999849035137053 52.914229034600936 -6614.40344713885 0.4000022238523015 19.99799834225505 4999.471790346645 1.4000033030824262 37.39407416590768 2670.998995757803 -0.400003390131593 19.997967442107 -4999.4494885476015 0.8000609327577811 28.275748164539177 3534.1993349273657 -0.6000010748783245 24.48996682612417 -4081.6538255519854 -1.4000841263719856 37.394064248538285 -2670.844097449836 3.714245414432433e-11 8.663775476790002e-10 2332.58024446236 +r_2890 PE (1-18:0, 2-18:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane 1.1999996491405502 34.62365490677659 2885.305419178609 0.8000010506647671 28.2757617593606 3534.465577997008 7.512196273275504e-05 0.0022035808801624 2933.33773506644 1.6000023264424394 39.971952159443205 2498.243377453065 1.0635421534559364e-10 1.2013285316915627e-09 1129.5542238621151 1.8000081049948935 42.39238262445377 2355.12176344195 3.633958869490097e-11 7.2612603958837e-10 1998.1680191395703 1.4000051897841683 37.394040832858536 2670.9930152918487 0.2000316211282299 42.43009946368636 21211.69604304041 +r_2891 PE (1-18:1, 2-18:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane 3.0682840545403193e-11 7.208462215397647e-10 2349.346438355623 -1.4000019261903829 37.39408755567453 -2671.002579077124 3.5560764923199065e-11 1.56060401554e-09 4388.555811188123 1.000009774849253 31.610087248333336 3160.9778267515862 -1.1999243865568547 39.98594214284586 -3332.371821993239 9.096995908141116e-05 44.72578553123613 49165445.365551904 -4.860042712790838e-05 40.00391791726745 -82311864.89777893 -3.0000890317183244 54.69540858870501 -1823.1261809379632 0.2002704554311326 54.77724168880204 27351.633854769152 +r_2892 PE (1-16:0, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane -1.8000307982277357 54.74780418374824 -3041.492636551082 -0.8000386657041627 44.718638030009096 -5589.559598428847 0.4000338090223442 19.99799882433493 4999.0771713042695 1.6000158944748537 48.96810978062736 3060.476458372893 -0.400007627879784 19.997960799565305 -4999.394862933807 -1.199990215497701 59.99384618207279 -4999.527946749974 1.4000448452664214 64.7987087790978 4628.330942268276 3.50015760020753e-10 5.382469823568161e-10 153.77792769242802 -0.200013937716139 37.419699605077305 -18708.54603051891 +r_2893 PE (1-16:1, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 0.600001207723504 24.489988779934304 4081.6565808014047 0.600003350961971 24.489977552911554 4081.640129783836 1.999992774910756 59.9725956983964 2998.640617642857 1.1565217210177311e-05 63.25181729953128 546914218.2982098 -1.800083089142989 50.963433644977286 -2831.171180505936 2.0791781943762888e-10 7.720722124138147e-10 371.3352778045178 1.2000173766547757 34.62366217290293 2885.263400886866 -1.2001008812351073 34.62361520454157 -2885.0587268053664 2.0000313568808417 44.68101981376942 2234.015964802268 +r_2894 PE (1-18:0, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane -0.2000094062041823 14.142135502615073 -7070.735207412134 2.5689559508174797e-10 8.136966366857811e-10 316.7421521676348 -2.800012748167843 52.8461118531789 -1887.352544653883 3.3999478302884856 70.63587837965184 2077.557712809328 -1.800125684111415 42.392382573142655 -2354.96793070138 -0.7999547571657893 52.91413242287575 -6614.64063422144 1.4000270726008608 37.39407403136992 2670.953638196591 -1.2000857214351592 34.62363313471772 -2885.096665704179 0.999920655337732 54.768516911984136 5477.2862846288135 +r_2895 PE (1-18:1, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 1.000000549246982 31.61009709761129 3161.0079735870395 -0.3999968782485275 44.72401870488437 -11181.091937696645 -0.3999741538192401 66.33762471328635 -16585.477856468253 3.120030664776246e-10 1.1814710220225394e-09 378.6728878535779 0.599982384871872 46.90498617251317 7817.727212529725 8.414576931810219e-11 8.44177524086439e-10 1003.2322847927568 -2.0000330112242017 72.0903833011821 -3604.459671245938 0.8000233345261255 28.27578233566961 3534.369700906048 0.3998415833297249 48.991282634499605 12252.673227861716 +r_2896 PE (1-16:0, 2-18:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane -2.200001841235409 67.79433995468804 -3081.5583279974976 -0.8000023649095576 48.988132664427255 -6123.498481153301 -1.7890898098125172e-10 9.589236309808347e-10 -535.9840661555847 -0.2000049441509884 54.77731579244551 -27387.98084465993 0.6000255145217535 54.7743204214696 9128.66521436628 -1.4000454445652268 50.97599579486574 -3641.0243676551454 0.2000063578527104 14.142121389517625 7070.835918092275 -1.6000965854915603 39.97192648182092 -2498.094605304171 -0.7999297481701114 34.63523162736156 -4329.78417249662 +r_2897 PE (1-16:1, 2-18:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane -5.4499026154684435e-11 8.254000611580626e-10 -1514.5225876428178 0.599981925108932 46.90498128540085 7817.732388669015 0.6000230735777556 24.489963498776 4081.503624977248 -0.8000124076617927 44.718629462667 -5589.741988298251 0.8001246335238829 48.98810596120394 6122.559399958994 -5.3314057606135765e-11 6.027928581175774e-10 -1130.6452466454243 0.600065748464062 24.489935166742384 4081.208639124499 -1.2000017984654685 34.62365428296817 -2885.3001993200355 -2.000314419743588 44.6810392651841 -2233.7008034422706 +r_2898 PE (1-18:0, 2-18:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 0.4000004435685752 19.997989149028133 4999.49174321346 1.3618213596006156e-11 1.1442224984483779e-09 8402.148272839153 5.536129468671174e-05 0.0018307760520948 3306.9603275269187 -0.80002408241764 52.91420249111697 -6614.0762077077 1.200079424226834 34.62359352049017 2885.108503780644 1.200041260875118 34.62367298680293 2885.2068770997066 5.931752791975927e-11 7.317607049669091e-10 1233.633178302348 1.599941083684861 39.969931610523744 2498.2127165875427 0.2000039609155904 46.9083630458145 23453.717031940032 +r_2899 PE (1-18:1, 2-18:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane -3.60001321631292 59.89784236283509 -1663.822846300036 4.0865399053342917e-11 1.5235278140523547e-09 3728.160863090178 -0.4000144613741899 19.997997979300468 -4999.318752277189 1.8000678367776557 42.39240305213661 2355.04474809262 0.0002058351247196 56.5741227835038 27485164.57556598 7.613690935449324e-11 1.721502699859855e-09 2261.061966469565 3.784583717648197e-11 7.789278459821461e-10 2058.159903689976 2.000125308587442 56.53875959565568 2826.760871076888 1.799835953931551 64.7888095300958 3599.7063726042093 +r_2900 PE (1-16:0, 2-16:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane 0.4000157179886077 60.004622999499176 15000.566303049143 -2.4000324815996303 48.93581797916077 -2038.9648204488 -0.5999975580253577 46.90496126205763 -7817.5253606741 2.200028303104078 46.85713630006013 2129.842431297278 1.199972794838799 59.993918305515145 4999.606538044436 -0.0001368144125091 60.00589396229741 -43859336.79194158 2.4000139012770045 48.935735705150535 2038.9771775535423 5.1827538377511225e-11 6.412148947432671e-10 1237.2088561734597 -1.600087606063877 52.89602010022136 -3305.8202500763387 +r_2901 PE (1-16:1, 2-16:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane 1.0000086504904446 31.610101951000896 3160.982851048141 0.8000190373862751 28.275776306143808 3534.3879313826064 0.5999954291871974 46.90498094222829 7817.556378016012 -2.6000316118675606 50.92892286245847 -1958.7809098165944 -2.20023137339286 46.85716612794452 -2129.6472132241524 -1.800072061332102 42.39235739418951 -2355.0366846323927 -2.000114388453976 44.68100767335555 -2233.922616190594 -2.000081940946416 59.972588104513534 -2998.506554993201 -1.200011419937053 66.32813506979961 -5527.291988044487 +r_2902 PE (1-18:0, 2-16:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -1.3999994554978283 37.39408518013832 -2671.007123130722 -1.2000532919977702 34.62365843288996 -2885.176738713892 1.9999905331281755 63.22017175630918 3161.023550317852 -6.483148430057717e-11 1.050595530086806e-09 -1620.5020468387654 -0.8000080345014697 28.27576680307132 -3534.4353536013614 -0.4000796010462724 56.57265587105724 -14140.35000112744 -1.0001835811566022 31.61007250692405 -3160.427055838138 2.000017263159322 44.681041950618045 2234.0328142987 -1.1008949858575498e-11 2.006221198421381e-09 -18223.547424540426 +r_2903 PE (1-18:1, 2-16:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -1.0000090817347047 31.61010455009325 -3160.981747811685 1.5999994387677352 59.98461197735853 3749.039563636136 -7.585689822698492e-11 1.102873137451582e-09 -1453.8864140628043 -0.8000006716189106 28.275123745966784 -3534.387501043994 1.799998505821234 42.39236009719627 2355.133071505252 -1.6000374543367264 39.971923218396064 -2498.186721195591 -2.1999886428129827 46.85566090495842 -2129.8137632677563 -6.211626012433968e-11 9.16532407827387e-10 -1475.511252597534 0.7998212905922708 60.00054572121282 7501.744005436788 +r_2904 PE (1-16:0, 2-18:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -0.4000043450868449 60.00463667648404 -15000.996217542695 -3.400063201622482 58.21609004193365 -1712.2061147026152 0.1999670929219275 54.77707503122141 27393.04464090391 -0.1999556012025214 61.64991698807213 -30831.80296891564 2.498948029763056e-11 1.4859318782279475e-09 5946.229615542827 -1.6000725060733785 48.968491381690605 -3060.3920257251725 -0.1999645394993661 50.99481209093776 -25501.9276010682 -1.2001964335856523 34.62360723809322 -2884.8283721901507 1.4000020443715584 54.75969762791126 3911.401261738309 +r_2905 PE (1-16:1, 2-18:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane 3.2000189717985936 56.48358090077192 1765.1014384150642 -0.8000154069067926 39.99596991680453 -4999.3999579891015 0.2000022532638984 42.43009811250977 21214.810043426973 -2.1999994371706624 46.8571624072756 -2129.871563400801 0.6001625239541042 50.99170748228436 8496.316488795594 1.400006194611164 37.39401912750877 2670.989547863718 -0.3999761749917901 40.00193132569468 -10001.078520868336 -1.4000054645645872 37.3940455859965 -2670.992830562011 0.6000278282358192 54.77438722331388 9128.64114725472 +r_2906 PE (1-18:0, 2-18:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -9.833680434016916e-11 9.55505637679475e-10 -971.6663502447832 2.069300620598428e-11 1.4891079509328374e-09 7196.189553657979 1.8744163038158297e-05 0.000985059963307 5255.289133485048 0.4000029250252217 19.99797390081369 4999.456916359485 6.790000000000037e-11 6.380603531037145e-10 939.705969224906 2.2000454833217806 46.85715557808141 2129.8266755527816 1.4000894485384274 54.75974410573718 3911.160402137279 -2.55159919904927e-11 1.07103013063179e-09 -4197.485761207549 -1.000090415261291 31.610042498265503 -3160.718472639979 +r_2907 PE (1-18:1, 2-18:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -7.882932910723749e-11 9.627363402609192e-10 -1221.2920637079585 4.781848716987254e-11 1.461360618519619e-09 3056.05782409681 -1.2000370897245196 34.623664161959326 -2885.216170269165 1.9999621271802288 66.30887404708218 3315.5064861439096 2.00011014369116 52.88245251015087 2643.9770168135565 -1.6000635925147426 39.9718946834305 -2498.144128172344 -0.6000475135208577 50.99170117011054 -8497.943916292566 -1.9173464139771445e-11 9.745861055749122e-10 -5082.994384688847 -0.2000532056741382 58.31493369926866 -29149.71219919187 +r_2908 PE (1-16:0, 2-16:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane 3.199999108039153 56.48356206329832 1765.1118064813918 1.1999693559489952 72.10795843918596 6009.149990514501 -1.4000311720331184 37.39408426817294 -2670.946548559303 -0.1999862173458131 54.77731256402839 -27390.543853983847 4.39991868012553 84.74697827614293 1926.1032859299369 -0.2000361687192676 54.777280933814026 -27383.68830223344 -1.200064936712135 69.27847631851951 -5772.89396591525 -1.0000840145524093 31.610071473750423 -3160.741599084314 -1.6003510704317407 39.97188495629698 -2497.6947680307057 +r_2909 PE (1-16:1, 2-16:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane -0.6000355787079303 64.81094298812226 -10801.183344441188 -6.986510980738839e-11 9.421127403524852e-10 -1348.4738561920285 -4.400003053214508 66.19291669502294 -1504.3834264311342 2.599992407554173 67.7801289970496 2606.935651047179 0.400001400882563 19.99794869316188 4999.469664115778 -4.8000491170754165 69.12236446137929 -1440.0345241361676 -7.935059478131984e-11 1.3595661634168252e-09 -1713.366065073132 3.60001739966128 59.89778936207111 1663.819440642337 2.600004084348022 78.70486200190362 3027.1053217072035 +r_2910 PE (1-18:0, 2-16:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane -1.000008263679531 31.610101406750942 -3160.984019316156 1.8000036403958468 42.39240912095355 2355.1290769406914 -0.8000190300401612 63.24677406108294 -7905.658701382133 -2.6000044118737287 50.92848432930235 -1958.784535007771 3.799999395344372 61.53293867076855 1619.2881174180338 -2.800087571035536 52.8455050888935 -1887.280442066676 -0.2000762597349267 50.99484859471039 -25487.705868887933 -1.8000997054804049 42.39235866779902 -2355.000589063787 3.399802734054649 64.72442447008686 1903.769998822716 +r_2911 PE (1-18:1, 2-16:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane -2.600009189790147 50.928758586770165 -1958.7914837670533 -3.4000006761015875 58.21581020719438 -1712.2293714936593 2.8000039746246133 52.846113080357405 1887.358502319351 3.1006143971152853e-11 1.919064515941645e-09 6189.3040222192185 -3.4000913096846785 58.21605299532524 -1712.1908705658889 2.1999677971047302 46.85650082831799 2129.872123127599 0.7999220972766913 74.83625324184926 9355.44267330867 -1.0413615950761895e-10 1.3168519714613843e-09 -1264.5482392358044 -3.423958736460209e-11 1.1220501672398098e-09 -3277.0551680182302 +r_2912 PE (1-16:0, 2-18:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane -1.799992702273689 42.39221304825678 -2355.1324955211426 -6.510212242334399e-11 6.354803471678816e-10 -976.1284632711368 -0.1999957572006363 58.31494187988744 -29158.08949956158 -0.3999917426957284 48.993010495409 -12248.505472943656 0.2001901796554928 42.42919924233604 21194.445859108782 -2.982704326483887e-11 7.388503681898394e-10 -2477.1156887039538 2.0000086704808995 74.81374887111025 3740.6712268463 0.8001055367305626 28.275717304793616 3533.998454795786 -1.200110480655198 34.6235969243845 -2885.034126648224 +r_2913 PE (1-16:1, 2-18:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane -1.8000316474627118 42.39239652917221 -2355.091733466335 -1.4000012694731514 37.39409199937067 -2671.0041494064376 -3.000027096149916 54.69520580251067 -1823.157059904684 -6.02941067026152e-11 7.01923272143845e-10 -1164.165638286834 -2.200002620984736 46.85718472059816 -2129.8694953201725 8.438649786987838e-12 8.680114782551455e-10 10286.14174264697 -1.3999980521085622 37.3939902650142 -2671.003020946668 1.421572243592407e-11 7.585340877433364e-10 5335.881388809836 -1.2346998021971992e-11 9.882860807411195e-10 -8004.262080405488 +r_2914 PE (1-18:0, 2-18:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane -4.0000353160657305 63.12520515883264 -1578.116195756991 1.6000666152154728 39.97196697161483 2498.143926728452 6.178142171141797e-05 0.0019474294538441 3152.127937328265 1.0000113229854055 31.61006208821568 3160.9704171996664 2.4002852093636595 48.93580274032777 2038.7495014936649 -0.8001130273997291 28.275770843404505 -3533.972060834624 4.472571723080775e-11 1.3210301808378995e-09 2953.6254813325927 -2.000286306453415 44.68097685682844 -2233.7290773164136 2.600283366511768 50.92888669334758 1958.5898732901464 +r_2915 PE (1-18:1, 2-18:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane 4.000008271066161 63.12520328529714 1578.126818934596 0.2000011101283983 50.99485758004776 25497.287263710525 0.7999786918695211 56.56849139656435 7071.249768461437 -6.128247816240412e-11 7.754043441440947e-10 -1265.2953460680928 5.367504735788074e-11 1.5764767918797823e-09 2937.0757353385343 -0.4000662390904141 19.997978434052342 -4998.666840651066 1.6002576940323388 66.31975880800623 4144.317446829036 -9.050057278552548e-11 1.389919730605217e-09 -1535.8131863973338 -6.799513788746412e-11 1.855643298990465e-09 -2729.082338301398 +r_2916 PE (1-16:0, 2-16:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane 2.0000011520892045 66.3089341112995 3315.444795720896 6.9645752021563e-12 1.4972185518048455e-09 21497.62919267915 0.4000041833723038 19.99799506452449 4999.446479766279 1.521774911686955e-11 8.647176566029934e-10 5682.296704736809 1.200000030751435 34.62360952143032 2885.300719513246 1.2000051318164484 34.62360430331453 2885.28801963578 -8.198515391904949e-06 52.92021346735525 -645485321.8865409 -0.4000762768465523 34.64213317929025 -8658.882114266702 1.999828680286336 63.22007930721208 3161.274759703927 +r_2917 PE (1-16:1, 2-16:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane -1.0000189971191735 58.30673381523903 -5830.562617631007 -0.2000348793253613 37.419761935394746 -18706.618596515185 2.156420075741375e-11 8.090483848399937e-10 3751.812524569656 -1.8975851411362972e-11 7.932386229088707e-10 -4180.253131798185 -2.204263024968035e-10 6.544549498493803e-10 -296.9041999236326 -1.8000456272630063 42.392391772502585 -2355.0731787260743 1.2000020306913872 34.623626534673924 2885.297328599132 2.2000016083298304 46.8571660456216 2129.869626831502 1.3998997380660778 50.975957900352704 3641.40063136054 +r_2918 PE (1-18:0, 2-16:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane -1.399999651807763 37.39408932262975 -2671.0070444906373 9.588972873846473e-12 1.688687402360847e-09 17610.722489023534 -1.6000162511798712 39.97195401780384 -2498.2217517058366 -0.6000237581773165 58.31220664465058 -9718.316291638974 -1.0000027691036468 58.30671027742567 -5830.654882054869 -5.460000000000002e-11 5.713879039911441e-10 -1046.4979926577726 1.0000001708634672 31.61007120726041 3161.006580625497 0.6000027182483433 24.48994952353813 4081.639762405485 2.9639281115856195e-11 1.7549701675887875e-09 5921.095591788582 +r_2919 PE (1-18:1, 2-16:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane 0.5999824564998899 54.77441851383357 9129.336686504204 -8.191082383609622e-11 1.1850318924008391e-09 -1446.734188355975 -1.2000153051990543 34.62365378529369 -2885.267682444303 -0.800002220086928 28.275761052890537 -3534.460323099866 -2.3267083547336068e-10 8.528075402900449e-10 -366.52962480451737 -1.7009469024002782e-10 2.211653094775837e-09 -1300.2481686258873 -2.000081026507999 44.68099401139735 -2233.959195613551 0.5999980270065924 24.4898856044087 4081.661022551932 -2.40007061521744 48.935772518526505 -2038.9305301374663 +r_2920 PE (1-16:0, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane -2.1055356134151225e-11 6.355137946295909e-10 -3018.299907066423 0.3999990483023066 48.99302339557589 12248.284990555409 -2.1999921156237368 46.85693884235606 -2129.8684895091674 0.1999784120384747 54.77730968188602 27391.611486217407 4.332676738943283e-11 6.66030819074323e-10 1537.2271212570654 -1.200010161565921 52.906664877071 -4408.85140572742 -0.4000367388655832 34.642141874083364 -8659.740095952413 -6.447456331637496e-11 1.0790743228608595e-09 -1673.643476367371 2.0000835375972734 44.68097583101712 2233.955481914169 +r_2921 PE (1-16:1, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane 0.8000007595525325 52.91423696364191 6614.273340595155 -3.000030266765773 54.69545578605776 -1823.163465781397 -5.86283558021334e-11 1.6037167945261163e-09 -2735.3944564615604 -1.4000005826205717 37.394086344657445 -2671.0050559166084 -1.0000349472744483 31.61010241712132 -3160.899776880126 -1.6000562178744575 63.23154475451531 -3951.8326948857584 -0.2000614517133693 14.14213538412281 -7068.895713295349 2.800101796997835 52.84608289850854 1887.29148901544 0.4002761186376956 40.00195592600887 9993.590440057224 +r_2922 PE (1-18:0, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane 2.1999997001415337 46.85719468464777 2129.872775965983 0.6000014039521175 24.489969855077167 4081.652091772699 4.036523321503999e-06 5.155638386397015e-05 1277.2472684428928 -1.8826843644769613e-05 44.72531145690425 -237561390.006708 -1.0000447358548743 31.610095995948026 -3160.868195453933 -2.8000299885037703 74.7881229958488 -2670.9757860776604 1.0158258324618216e-11 1.259081967830553e-09 12394.663805499098 -1.199986833611829 56.56140962777221 -4713.502518817526 -0.8000047176585849 28.27575456348366 -3534.448477533954 +r_2923 PE (1-18:1, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane 0.8000000471383536 56.56850657381607 7071.06290507918 4.1965927880761495e-11 1.8088061359495158e-09 4310.1778687913375 1.799990909726412 42.39211800797029 2355.129560871707 1.0000262520243033 31.61004599244027 3160.9216186528733 1.800168048499386 42.39241172883061 2354.9141294985643 2.000055318327528 52.88239703658092 2644.0467197078265 -1.800160979675162 42.39242322234675 -2354.9240151842664 1.4000901807926125 58.298449430847086 4163.906741910257 -1.6000006831458509 39.9719501193922 -2498.245815795597 +r_2924 PE (1-16:0, 2-16:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -2.2000088824414683 78.71704372038398 -3578.0329956226105 -2.699678212300664e-05 56.57387493680316 -209557845.3722117 1.6000009592717537 39.97193812710893 2498.244635134613 -0.6000259277167409 58.31216165184997 -9718.2736542308 -2.000001105373733 82.44598467047173 -4122.296955184199 0.999962779613064 42.41881308152156 4242.039198492522 0.4000706349277884 19.997915976651853 4998.596305440268 -0.8000677237854115 56.56841659356039 -7070.453526848281 1.2000082219646933 34.623617330386146 2885.2816752954586 +r_2925 PE (1-16:1, 2-16:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -6.622462548473601e-11 7.93642723011049e-10 -1198.4102849988546 -3.978256749104876e-11 1.1100828048168866e-09 -2790.374967796284 -0.3999895179110354 60.00462380750365 -15001.549070805831 1.799977239144373 67.80612301462199 3767.054468247273 1.0000001944314982 31.61008037464438 3161.0074228650287 2.40000111987116 48.93582305832072 2038.991676010041 -0.600130347205601 54.7743905940017 -9127.082282882177 0.6000023204498278 24.48997070617057 4081.645998937169 -2.400083921077038 59.95790723926071 -2498.158781562712 +r_2926 PE (1-18:0, 2-16:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane 3.799996909182205 64.70232696469716 1702.694199786118 -0.6000031638193314 24.48997422748552 -4081.6408486238856 -4.879762468422938e-06 60.0059368750067 -1229689708.5320563 -0.8000479581640123 28.27574539009315 -3534.25630320733 -0.2000444483691301 42.43012212561257 -21210.347236089645 -2.4000529551456524 48.93582646046311 -2038.9477805290064 -5.058280783495686e-11 1.3844154545617798e-09 -2736.928837716746 0.5999768035708122 46.90493348399138 7817.791155396799 -1.2001709396251303 34.62366112686867 -2884.8941416364623 +r_2927 PE (1-18:1, 2-16:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -4.4716272001318166e-12 7.337397641305845e-10 -16408.786584645404 2.00001400720404 44.68106301866118 2234.0375046234785 -1.800028492856628 64.7885892257058 -3599.3090933181243 0.1999414180970946 42.4297170457173 21221.07437745229 -0.9999762272606773 58.30675403493572 -5830.814017915259 1.000001846668012 31.61010336651532 3161.0044993256374 0.5999261364860919 64.81077017228291 10803.124956664631 2.399997091380882 48.935802392159424 2038.994237447318 1.600083412298818 39.97190634628875 2498.113913252913 +r_2928 PE (1-16:0, 2-18:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -2.000008345877015 44.68106017772083 -2234.043686359116 3.3999999501446108 58.21609033381216 1712.2379761016196 -1.6000038551475904 39.97194140322352 -2498.2403182732555 2.20003601418755 70.68342112015844 3212.830183885016 -2.6000104965290056 50.92892867627361 -1958.797041175924 1.4000078324939618 37.3939807498372 2670.9836818001145 -1.0000053742065145 50.98546354416929 -5098.518953923154 -0.5999047101360557 54.77437254602329 -9130.512166440683 -0.4000256474449658 56.57268409795061 -14142.264242128049 +r_2929 PE (1-16:1, 2-18:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -3.393642174776353e-11 1.014218154226748e-09 -2988.5830679646924 1.2944347546782151e-11 1.904775550192668e-09 14715.114402704508 3.20000063520595 56.48353094181664 1765.1099915541547 2.200047109752824 73.45901344564187 3338.9745664989427 1.2000493589320094 34.62362611911217 2885.183501945758 2.600012676556287 50.92887950145621 1958.793507457488 2.598995559596988e-13 8.347733119742361e-10 321190.74189710425 -1.8000868954319744 42.39240716083442 -2355.020041999769 2.4001686754603777 48.935774378798826 2038.8473059882936 +r_2930 PE (1-18:0, 2-18:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane 1.0000010893672493 31.610106777624367 3161.007234264681 0.6000187399928506 24.48999654560614 4081.5386109270426 -5.5657877420726174e-11 1.8114867904195887e-09 -3254.6817707874325 -4.3999919231487805 77.34219084373191 -1757.780291296155 -0.4000615431351061 40.00192329897819 -9998.942409085545 -3.1999989813616287 56.4834998584678 -1765.1099324548395 0.2000709850461679 50.99486612612813 25488.38659156932 -2.600013371967424 50.927255955277566 -1958.730539787225 -0.0003058497320661 56.57409427916995 -18497349.628845423 +r_2931 PE (1-18:1, 2-18:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -1.199998791909174 59.993962890051314 -4999.501940714635 1.0000164481205702 31.610106185806185 3160.958626752008 -2.000001950734034 44.68105929506792 -2234.0507857339453 -3.800012727015222 61.53298759129951 -1619.2837238108816 1.6000384889661785 39.97192135851758 2498.184989558867 7.002484251721249e-11 2.07472580074987e-09 2962.842508699525 1.8000112115628757 42.39241637728297 2355.1195739761747 3.470811723767303e-11 7.702832469938818e-10 2219.317290301756 -3.200165962630777 56.48347887549524 -1765.017175204925 +r_2932 PE (1-16:0, 2-16:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane 0.9999997748051014 31.609819767843664 3160.982688621543 1.9999541615796603 52.88245639834644 2644.18342251291 1.1453261959141411e-11 1.5745236421920102e-09 13747.38173115219 -1.0000452252804373 31.61008872562084 -3160.8659215143584 -8.600073560215993 96.5809467905449 -1123.0246591997668 -1.0000020813853112 31.61006983313968 -3161.000404054158 0.3998860148942399 48.99296705592667 12251.733051700774 0.1999327701359918 61.64987703859419 30835.30378569792 0.2000186009872593 64.8134504370255 32403.711513387672 +r_2933 PE (1-16:1, 2-16:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane 0.599997167473255 70.71505348872942 11785.89788790654 1.200000781433146 34.62366599527377 2885.303620712909 -0.2000463321555045 67.82968668306272 -33906.98842223002 -7.046959909238372e-11 6.926250765742891e-10 -982.8707492237564 0.8000047395368995 28.27576871213097 3534.450149445243 1.599990926297652 59.98456639917133 3749.056661088351 1.4000022300878996 37.39408044216921 2671.0014911777257 -1.8001819267421195 67.80608865700755 -3766.624231125332 -4.996127913561239e-11 1.7259396930884763e-09 -3454.554653021738 +r_2934 PE (1-18:0, 2-16:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane -1.4000071613569869 37.39406505257538 -2670.990983812568 -5.4685837751513433e-05 34.64444761486491 -63351772.66970939 -1.0263256666188048e-10 7.846552506414762e-10 -764.5285275057929 4.199977865660797 64.67721006486116 1539.9416885899534 1.6000090889633496 39.97129116441822 2498.1915065442363 5.199992093435397 71.93032321572741 1383.2775497203943 -9.012147253440348e-11 1.673235975367401e-09 -1856.645179347963 -8.211901400107025e-11 6.739643868855215e-10 -820.7166087950568 -1.200200981308062 66.32813902483048 -5526.419329581075 +r_2935 PE (1-18:1, 2-16:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane -0.6000256510077701 50.99172738604131 -8498.257916207152 -0.8000172252233254 28.275766143099005 -3534.3946669655525 0.5999450259072211 54.77440061966375 9129.903283527578 -0.400017796311112 19.99796826030716 -4999.269643682008 2.399999858546489 48.93579940141444 2038.9917619016608 -2.800006967758928 52.84553101986164 -1887.3356969592896 -3.8000650076571576 61.53297613214092 -1619.2611444317804 -3.2003867249377045 69.21492715841335 -2162.7051074510573 -2.2001157397613373 46.857165800547946 -2129.759128291628 +r_2936 PE (1-16:0, 2-18:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane 5.999997107608638 77.23450202842439 1287.2423210085014 1.0000350387794663 46.89814369337441 4689.650049723574 1.1999791369701136 44.70967330097144 3725.870885877324 -5.159999999999995e-11 5.412910854686803e-10 -1049.0137315284512 1.000066708598001 58.306000741004326 5830.21114888864 3.4001455894344894 58.21602194313124 1712.162623977925 -0.8000070917080494 66.33421354326777 -8291.703189985652 -1.0003591167884505 31.610050048289224 -3159.8702423755603 1.2000900479879903 34.62360726383855 2885.084108637241 +r_2937 PE (1-16:1, 2-18:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane -1.200041069963056 34.623677738094976 -2885.2077320287785 5.200015933228642 71.93043528195608 1383.273363112469 0.400053711800873 66.33786345033515 16582.239207757895 -1.600085770045068 39.97195231619042 -2498.1131052158885 -4.2599999999999845e-11 7.370847297155103e-10 -1730.2458444026129 -1.799999870277594 42.39235935875866 -2355.1312452161987 3.0000760135325635 54.69538665696312 1823.1333609630703 4.400224326301774 74.71101351637522 1697.8910159147968 -3.200282282211174 56.483491665425625 -1764.9534223712112 +r_2938 PE (1-18:0, 2-18:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane -0.7999974362446218 44.71864009462572 -5589.847925581568 -3.00001601104585 54.69547374001916 -1823.172727699927 4.537227254208328e-05 0.0015663221887399 3452.1572338860005 -0.4000050248904284 60.00427021419143 -15000.879109113224 0.2000225310469874 14.142121174794823 7070.264085135833 -1.795715208570586e-12 1.1192610219782919e-09 -62329.53959716358 -1.6000638804880092 39.97187672320451 -2498.142556096782 -2.599999999999996e-11 6.677673117460313e-10 -2568.335814407817 0.8001970242782525 28.275701497372825 3533.5924327982148 +r_2939 PE (1-18:1, 2-18:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane 6.737721295905909e-11 1.3523072022709342e-09 2007.0690711007096 2.8000500629229776 52.84614718810582 1887.3286548648207 1.3411980439701278e-11 1.708636711000797e-09 12739.630203627506 -0.2000417777828746 14.142105580434274 -7069.5760341542855 -0.4000352227666681 60.00460428647137 -14999.83023281696 2.9778096500574467e-11 1.217573174718e-09 4088.821374779652 -4.048979359078694e-11 7.052293485149461e-10 -1741.7459709535644 -1.2000041345465573 34.623644948684785 -2885.2938045724263 1.200011063414003 34.623670128740166 2885.279243196029 +r_2940 PE (1-16:0, 2-16:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane 1.0000012883927571 31.610103403058343 3161.0062676882544 -1.2862819919925875e-11 9.73363040481377e-10 -7567.26010735433 -1.199981957842599 63.24041254594177 -5270.11361567796 -0.8000616327545786 28.27576006031312 -3534.197729612513 2.6000137714137583 61.59537948339652 2369.040508962536 -2.291522838674965e-06 56.57410165035594 -2468843019.8264565 -4.000124242933653 63.12511031254724 -1578.078741530585 -0.0003157750289725 66.33897241142488 -21008302.2166991 1.40001801083882 37.39396792801232 2670.963347507776 +r_2941 PE (1-16:1, 2-16:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane -9.104701887121672e-11 9.658503264526396e-10 -1060.8258660492834 -3.0000176197014827 61.57695374343154 -2052.55306965693 2.399973486128339 72.07821723872154 3003.292230323712 -3.200011914934352 56.48330281697852 -1765.096640839766 1.600049580898068 39.97189997009328 2498.166334799328 2.600007592507768 50.928873677246045 1958.7971136701167 -1.400122439408911 37.3940822368599 -2670.7722970747154 -3.000193777963972 64.7442293934476 -2158.001588730217 -2.4001164830684067 74.80200768568906 -3116.5990573115487 +r_2942 PE (1-18:0, 2-16:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane -0.8000186931486245 52.91392493946452 -6614.086069815668 1.1224676645403965e-12 1.92093482491004e-09 171134.98104166618 1.1999771374704895 69.27850775159835 5773.3189731960265 -2.4000048852835194 48.93539337589068 -2038.9705735998864 -1.4001318866605237 37.39409596952603 -2670.755257114761 3.40001061964058 58.216010287787945 1712.230248679107 -1.2001438397493056 34.62366850912255 -2884.9598991696685 -9.267004792141932e-11 9.86658377242018e-10 -1064.7004068441477 -3.9648019675473375e-11 1.88919240885918e-09 -4764.909885342525 +r_2943 PE (1-18:1, 2-16:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane 0.999998978348707 31.610079131073427 3161.011142558464 -1.1630477999764871e-10 1.6261776658806319e-09 -1398.203638675476 -1.0682019640443308e-10 8.884580907695833e-10 -831.7323134342337 -4.446957802950298e-11 1.2967897551155764e-09 -2916.1278621875663 -1.5436459714194598e-10 8.671362006254652e-10 -561.7455146325359 -2.2908920307357016e-10 2.482627985485776e-09 -1083.6948892298954 9.399941862504104 96.50565857065224 1026.66229198298 2.200003167703138 46.85710840016073 2129.8654969247523 1.8000039183460708 42.39234458679528 2355.1251280467977 +r_2944 PE (1-16:0, 2-18:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane 2.8000539528583377 52.84613939294351 1887.3257545268857 -1.00002444039058 31.6100943573248 -3160.932181315371 2.800009072027813 63.18956390474647 2256.7628275212533 -2.6000435089667544 50.928912559576254 -1958.771550704364 2.400070285587252 59.95784599002649 2498.170422344775 2.1075362284542242e-12 7.673274343066921e-10 36408.74230045809 -1.0599999999999998e-11 7.355241934619591e-10 -6938.907485490184 2.600148970721204 50.92880240028037 1958.687866493828 -1.399943860190428 54.75979189965464 -3911.5705605656153 +r_2945 PE (1-16:1, 2-18:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane -3.2000164077184574 56.483586674148285 -1765.103033156629 0.1999893465418357 42.430140646420206 21216.20045272974 -1.8000284750646467 42.392404669811626 -2355.096336367076 2.399955755879396 63.20625872100744 2633.642664710179 1.0000034053055284 61.64212497790071 6164.191506834654 -1.3999420248402847 61.63431721301343 -4402.633546203108 -1.0001911557177052 31.61010458311745 -3160.4063285717666 -1.4002958918346329 37.39405867089701 -2670.439789829294 1.8000179309485462 42.39240379665656 2355.1100835044044 +r_2946 PE (1-18:0, 2-18:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane 8.634629550831895e-12 1.1051794310234071e-09 12799.384438176963 -0.5999966313288615 50.99173243726065 -8498.669788249494 1.2160842222940655e-11 1.034894793231525e-09 8510.058549063828 2.6000089133138697 50.92891002200427 1958.7975164705213 -2.400077194712981 48.9357779922593 -2038.925168742808 1.600085535467744 63.23155164756339 3951.760718159312 -3.231017421094523e-11 1.498847262866396e-09 -4638.932780370631 2.8003048638964927 52.846086124974 1887.1547454101533 -2.000340046258365 44.68095722332739 -2233.6680859288444 +r_2947 PE (1-18:1, 2-18:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane 7.605786934815352e-11 1.8356406028554637e-09 2413.478866273328 -2.6000469320546675 50.92892495057499 -1958.76944845487 1.000038848887959 58.30671965099816 5830.445458777436 -1.8000015377892953 42.39241434879852 -2355.1321184349395 -3.800031933459356 61.53298179639371 -1619.27538699332 2.757906918047232e-11 1.3390063147980332e-09 4855.15412444062 -1.000117223319572 31.610100318776663 -3160.6395312198465 0.8000224695077721 63.24675023733703 7905.621735380846 1.8001130098002796 42.3923588560036 2354.983194122184 +r_2948 PC (1-16:0, 2-16:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane 1.7999999431828864 42.39240468607646 2355.133668010857 -0.8000481921084095 28.27575679814012 -3534.256695665235 1.400017251981491 37.39407782725333 2670.972645110497 0.3999682156207647 48.99297291424978 12249.216562923872 1.199957419253544 66.32815551137512 5527.5424316836 -1.2000705000130782 34.62362840518411 -2885.132865511383 4.679999999999831e-11 6.330007093041702e-10 1352.5656181713532 -1.2001074368388365 52.90659575071192 -4408.488284188243 -2.800338106312809 59.94035392814813 -2140.468459612946 +r_2949 PC (1-16:1, 2-16:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane -5.4000585390939415 73.29328463066014 -1357.2683351495257 0.5999848306946964 54.77440607378957 9129.298487491536 -2.2000172734405847 46.85718299039836 -2129.8552314145645 -0.800054488597967 56.568453488961 -7070.57510396483 -0.8000449065447877 28.275748311879127 -3534.27014915896 -0.4000721199747362 19.99797832423792 -4998.593334996888 -0.6001306453390982 61.64630944920463 -10272.148227719976 1.3367665583280214e-10 6.524743443706639e-10 488.0989431593463 1.0000125248060918 31.6100422017351 3160.96462970446 +r_2950 PC (1-18:0, 2-16:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane -3.200026975160552 56.48342141679239 -1765.092040011897 5.735722252175226e-11 1.2356368621936292e-09 2154.2829444452686 -0.400055935610552 19.997981382827305 -4998.79631889652 1.199977258186902 56.561401042960725 4713.539415607077 1.0372976673548124e-11 1.7135686234459804e-09 16519.54571358201 0.3998721862447469 60.00458180926995 15005.940366290786 -2.2001266546117835 46.85711796949359 -2129.746388521511 2.599906913103588 67.78008610651051 2607.0197269331984 2.200000644700928 46.857025146368194 2129.864155232465 +r_2951 PC (1-18:1, 2-16:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane 6.999995855836264 83.38093810482995 1191.1569638332128 -1.4000491876589978 37.39408442359066 -2670.912190315026 -1.6000630103321227 39.97195791293724 -2498.1489888101546 -1.600118427801574 39.9719121496912 -2498.059609538351 -1.6003047272755666 63.23151201292109 -3951.216973567863 0.1999009938389224 50.99481714232824 25510.0368252392 2.799884700689138 52.843840965918034 1887.3577527285868 -2.000193913333891 44.68102879756502 -2233.834854696233 2.999837395090836 54.69532580041825 1823.2763512424333 +r_2952 PC (1-16:0, 2-18:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane 0.5999697623585649 54.77439980157396 9129.526725855008 -6.40523164062064e-11 1.596765640510648e-09 -2492.9085005830148 1.2000007157037929 34.62361828200186 2885.299802650145 -1.4000399688953409 50.9760276335622 -3641.040882124479 3.1998320586451423 59.92049533686851 1872.613757180737 -3.600320170598064 59.897804820223406 -1663.6799501715857 1.800001515556086 42.39234390513992 2355.128233991702 1.199784618031818 56.56138188702975 4714.294635633489 0.9997383581840084 58.30659330608283 5832.185274154613 +r_2953 PC (1-16:1, 2-18:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane -0.8000655353842596 44.71864792415658 -5589.373113376128 1.4000002342884192 37.39408676587821 2671.0057505729324 -9.940000000000079e-11 5.29505160638722e-10 -532.7013688518286 0.3999975912106727 40.001964461065725 10000.551338319758 1.2093703695784063e-11 1.0860945541138164e-09 8980.661188949383 0.600001476939518 24.48997304427133 4081.652126789681 -0.2000739842503163 37.41976538203918 -18702.964067143585 1.0000016740594448 54.76851162058984 5476.8419934999165 0.9998185624263012 58.3066295736574 5831.721050683665 +r_2954 PC (1-18:0, 2-18:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane -0.8000620299909127 52.91422199593705 -6613.764934768627 -2.8000940599532225 52.84612885782609 -1887.2983452101928 -2.400122425233272 48.935808550856 -2038.8880182268144 -1.4000527595771568 37.394058494315104 -2670.903524064968 -9.472582328508035e-12 1.4811563387540752e-09 -15636.246668413629 0.4000017665666898 19.997971198011378 4999.470719756744 -2.400187274241276 48.93576091628329 -2038.8309462957388 2.7999957060632643 52.84606626377149 1887.362403782824 2.199820574249643 67.79433263057405 3081.8119179423825 +r_2955 PC (1-18:1, 2-18:1) diacylglycerol (1-16:0, 2-16:1) acyltransferase, ER membrane -7.014124466303563e-11 1.176221134188219e-09 -1676.9322241697928 2.400016646731108 48.93582285320473 2038.9784762475192 0.9999998009979228 31.610077373199545 3161.0083663671853 -2.6000525785671407 67.7801209129786 -2606.87500982505 -1.1075926693806184e-10 1.299096706725818e-09 -1172.90114194444 0.6000043912681247 24.489973788838725 4081.632425569176 1.1998111576861084 48.979931474380976 4082.303382545721 -3.0004350051396016 54.69536402579953 -1822.914475138071 -3.800469977948602 76.07029991467046 -2001.602442751864 +r_2956 PC (1-16:0, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 0.4000065340704414 19.997989366696054 4999.415675338541 1.3999639730865452 58.29849491450216 4164.285369856312 -0.8000676712749317 63.24675753824864 -7905.176000607929 -0.4000389896908112 56.57274922668585 -14141.80884478554 -3.4001460022055805 58.21594527789877 -1712.1601613617677 -0.0003305894270401 60.00586402921921 -18151174.57520128 0.4000794976379514 19.9979598083402 4998.496530416358 1.600168347507548 39.971932706024525 2497.98296337292 -1.0001150298942574 67.82251032181874 -6781.470960294402 +r_2957 PC (1-16:1, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 0.2000105578317511 14.142132835411743 7070.693161762043 2.23597960899092e-10 6.383012539348452e-10 285.4682803761817 1.400011008092369 37.39408218563061 2670.9848686535083 -2.600048005461903 50.92847987933868 -1958.7515219855009 3.799859372531059 64.70233702394225 1702.75609386156 1.6000267894507374 39.97194329650455 2498.204627575408 2.5998429502576403 70.66898374243972 2718.202025835312 3.738256706451256e-10 5.738224255131678e-10 153.50000563709276 -2.200057972274417 67.79295126948259 -3081.41658646378 +r_2958 PC (1-18:0, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 1.39999468743433 37.39389292207687 2671.0024872027184 -1.0000166645924278 37.40690336465941 -3740.6280004248906 -2.600038581738994 50.928853049249945 -1958.7729738682183 -2.8000985155270826 52.84608864485632 -1887.2939059756163 2.9999606019264755 70.65397043567347 2355.163277487772 0.4000222875671674 19.997990870663468 4999.219166583467 -2.200018757211423 46.85589972577272 -2129.795465251565 2.199780425728711 54.73348885129306 2488.134188809401 -2.8000959917512693 52.84598019653669 -1887.2917340053448 +r_2959 PC (1-18:1, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane -1.600035676703191 39.97195616790077 -2498.1915559696376 0.1999530946768275 54.77732855585644 27395.089155479105 2.800007070775885 52.84587556200702 1887.3479325665903 0.7999836764412055 80.00387133847423 10000.687975831976 -5.380444388528726e-05 52.92026393531366 -98356678.58242583 2.4476456215755927e-10 6.960193737895199e-10 284.3628046700158 -2.800288217970684 52.84605342619194 -1887.164795646945 -2.200354711069193 46.85710418739298 -2129.525023927813 2.799578563801093 84.8149898086991 3029.562767245317 +r_2960 PC (1-16:0, 2-18:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 4.199999239846953 64.67757347055456 1539.9425042017722 1.800001508444944 42.39241136011604 2355.1319907914776 -2.0001141162235285 44.68082069796794 -2233.913572008133 -8.346537716945419e-11 5.51426944860332e-10 -660.6654921606676 6.1999858046168 94.67477299599663 1527.0159638994237 -2.0000474153077907 56.53874582245693 -2826.870272660815 0.9994974975375356 58.30665606061134 5833.597002920125 -1.200204192628397 34.623646321106406 -2884.8129788050537 1.0000177854860783 31.610091992657114 3160.9529801804883 +r_2961 PC (1-16:1, 2-18:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 2.0000079169193574 44.68106075384869 2234.044194318571 -1.600103563846056 59.984625106635136 -3748.796419305156 1.9999756467445 44.68049018536468 2234.051712484312 -0.2001222988854114 54.77732334564058 -27371.92389390133 -5.200190449870241 71.93029902043928 -1383.2243206060682 -0.8000819471998454 52.9141841927912 -6613.595567051864 0.7999994541095038 28.275722134240617 3534.4676785704705 -1.00029750747164 31.61008314826038 -3160.068170934293 -4.2059989805267895e-11 8.802166311221007e-10 -2092.764727707699 +r_2962 PC (1-18:0, 2-18:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 1.5999990245382532 39.97195142954436 2498.248487437668 -7.732298225394001e-12 1.0414876907229076e-09 -13469.316112284829 1.3999995064849342 37.39405972135863 2671.0052073694096 -0.4000705588443491 44.72398830609247 -11179.025128788024 0.7999134846884141 48.98810338730531 6124.175217072053 0.6000010396724026 24.48997387116103 4081.655239219656 -1.8002348518793354 61.62389991404503 -3423.1033717469386 -3.400413117561848 67.74469754074671 -1992.249035591322 -0.2008586647826626 37.41971942417523 -18629.875621579435 +r_2963 PC (1-18:1, 2-18:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane -2.4000538863596126 59.95794032694484 -2498.19142260546 -4.645639398089973e-11 1.7617147344039723e-09 -3792.190016143508 -1.60013719151208 39.971901412645714 -2498.029645500178 0.5999033740381677 64.81103087444124 10803.5783226513 -4.400449350214607 79.88678904680839 -1815.4234417653813 2.399998486470776 48.935793190103645 2038.992668785565 -0.8002422854223409 28.27574911666652 -3533.3985258906346 4.799662928514252 84.72529984261719 1765.234373840584 -1.0988916007771339e-10 8.848152356596612e-10 -805.1888239330628 +r_2964 PC (1-16:0, 2-16:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane 0.9999560779802766 42.41883540905565 4242.069861181676 3.3999977618116906 70.63588378812312 2077.527361385225 0.3999612493709789 63.25053989032223 15814.166994876798 2.8000197186875053 52.84611194022928 1887.347849285884 -0.0001148356107908 60.005907840809975 -52253745.53028534 6.356522632246883e-11 7.57172646997446e-10 1191.1743114958488 -0.8002253267460069 63.246397537214094 -7903.573584004875 2.134253242526851e-11 8.67869705500219e-10 4066.38578874878 1.6000059067734862 39.97191027681922 2498.235169482913 +r_2965 PC (1-16:1, 2-16:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -2.0569997626223808e-11 1.2050567945206963e-09 -5858.3224773172615 -2.6000324888714514 67.78015412110607 -2606.8964296106224 0.3999417460000293 72.11703998556149 18031.88607011688 -1.8001176189391208 42.39240770714457 -2354.9798780441947 -1.000048478790265 31.61007844655591 -3160.854610247882 1.4000048115312878 37.39405039081051 2670.994419648451 4.399949456604126 66.19210339024099 1504.3832671961634 -5.000143278891741 70.53937690818597 -1410.7471121071694 2.199911876134173 46.855272645604174 2129.870434989481 +r_2966 PC (1-18:0, 2-16:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -2.61028996364152e-05 52.920283302759714 -202737182.61143893 -0.3999832386519551 66.33788933978637 -16585.167309350727 -2.600035015817859 50.92891755530251 -1958.778141273704 2.599887447387886 58.25701244213406 2240.751325626232 -1.40010795996975 37.39405062468384 -2670.797659452758 1.000000144849006 31.6100612349398 3161.005665625452 1.8666189414405524e-10 6.75584349736177e-10 361.92944083959566 3.1995239152625654 82.40708144687466 2575.604484585076 -0.0001125384304989 52.92017476492431 -47024091.70832457 +r_2967 PC (1-18:1, 2-16:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -2.6720584639747247e-05 56.57416351739881 -211725021.29030493 0.7998690684736686 56.56850351260388 7072.2204098415 -0.2000184588879803 64.81348598339977 -32403.752305530128 -2.4002174650180965 48.93580134120963 -2038.8069853845795 2.3999619805492736 48.93495056418691 2038.988574018464 1.3999993644240691 37.39402047769633 2671.002675281889 -0.8001767062676121 28.275778600943337 -3533.69179325832 1.799664645365467 58.28750703683103 3238.798249825833 -1.8000771661123676 42.39229777024328 -2355.026693761027 +r_2968 PC (1-16:0, 2-18:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -1.4958884208308542e-10 9.129199643447843e-10 -610.2861360727196 -7.933292830387007e-11 8.38586523888327e-10 -1057.047233497139 -1.2000309132434803 48.97993274792688 -4081.555917217366 -0.6000225160610765 24.489977057560385 -4081.509677058109 -1.400089584821367 37.394075639922775 -2670.8344984005985 -0.6001297751841397 58.31219259622505 -9716.597144064872 -0.6001588366261991 42.42628107769054 -7069.175439653684 0.2000883320958147 50.9929973673538 25485.24285910643 -1.8004513066856431 42.39239025773218 -2354.542447236194 +r_2969 PC (1-16:1, 2-18:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -1.84093383147836e-10 6.57596406024778e-10 -357.20806189796406 1.6000018355483725 39.971959370736606 2498.2445946405383 -1.4000556187246551 37.394070773925534 -2670.898946713896 1.2000025084324195 34.62364004933133 2885.297306133192 -0.2003237044202877 31.62526981202953 -15787.0831629982 0.599921116377096 58.312199698818304 9719.977861583498 1.600001170791076 39.97191522501495 2498.242873488146 3.800003842459085 61.53293157338669 1619.2860356048238 0.9994995484918604 58.30665264735598 5833.5846909920665 +r_2970 PC (1-18:0, 2-18:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -2.800091115081901 52.84612975840437 -1887.3003622547712 1.8000015356449193 42.3924187246496 2355.132364343284 2.000014038107938 44.68103798001751 2234.036218180091 -0.2000613947459827 46.908393682531226 -23446.99922845717 -1.000201817095186 31.61006205363789 -3160.3683889958047 -3.157191378900729e-11 1.1325026723782107e-09 -3587.057407880436 -2.400179085347117 48.93573874075399 -2038.836978436417 -0.8004360773169586 63.24667627323228 -7901.527438047711 -3.4095490376495726e-11 6.926424468169837e-10 -2031.478178400004 +r_2971 PC (1-18:1, 2-18:1) diacylglycerol (1-18:0, 2-16:1) acyltransferase, ER membrane -1.930793614039112e-10 8.771008330025429e-10 -454.2695949608499 0.7998930583877927 48.98812412937097 6124.334198887529 1.3999984992701615 37.39405015004989 2671.006445331472 -0.4000844728069549 56.572335462463634 -14140.09773125097 -0.0001007754344388 44.72580881471898 -44381658.15286488 -0.4001470145748358 52.91875300093929 -13224.827644201348 1.1996950178903636 56.56137793634998 4714.646397032796 -0.6003051365161839 24.48991606620876 -4079.577964022389 -8.824454620746428e-11 1.5663591194381034e-09 -1775.0208786337566 +r_2972 PC (1-16:0, 2-16:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane 0.5999961884698375 58.312215525737294 9718.764326561835 1.999999418205105 74.81382768657858 3740.692472486821 0.1999701675003716 70.71714016032303 35363.84503963153 -2.000151000905188 44.68103557510893 -2233.883119568877 -11.200511357872449 112.59229498319291 -1005.2424517569524 2.600032878907796 50.92885325729412 1958.7772781814965 0.8000182562481275 28.2756686319688 3534.3779233956675 3.200070290222856 66.26173038378685 2070.6335915881496 -3.6002083543609507 59.89773246203077 -1663.729611356419 +r_2973 PC (1-16:1, 2-16:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane 1.4000009595986924 37.39409988184457 2671.0053036366144 -0.4000166191382578 72.11707272576116 -18028.519135310053 3.200010740805752 56.48352381551264 1765.104194659368 3.1119409350140377e-11 1.0055325781309354e-09 3231.207144124025 5.799990592189719 75.9439569824497 1309.3806925258812 0.5999351281741684 46.90496589673435 7818.339632733971 2.799774052545561 87.14101391019742 3112.4302273952644 -1.200276590496126 52.90657534674495 -4407.865300853397 -1.6004396510979548 39.97192300149933 -2497.5589035223707 +r_2974 PC (1-18:0, 2-16:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane 0.1999718550610685 73.49148912223417 36750.91632259497 -2.4000770151850497 48.93583319082556 -2038.9276211227127 5.797356572967001e-11 6.69701922144956e-10 1155.1849773528986 3.0299689771200605e-11 1.6121293543232379e-09 5320.613400654493 -2.400101814836068 48.935798243371686 -2038.9050973120527 -8.9425688315506e-11 7.36794463394864e-10 -823.9181350165883 -4.000005057551638 63.12514885926464 -1578.1267261172638 -1.6005129984005313 39.97192537554231 -2497.4445952946435 2.3999125457084123 72.07813770027614 3003.3651780006817 +r_2975 PC (1-18:1, 2-16:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane -1.200017147019366 34.62365934592807 -2885.2637174333063 1.1999032215373708 63.24043007311226 5270.460895345021 0.3999550699374762 48.99300785111896 12249.627904148803 2.199908674886136 73.45870065609367 3339.1704616963607 2.600026850694578 50.928857915826185 1958.7819988174704 2.399997930534027 48.93576774660452 2038.9920809521595 0.999803465506182 67.82196030650508 6783.529228133659 -1.200475155148176 34.62361088441675 -2884.158887914937 -1.6003214397167047 39.97187109722126 -2497.74014802284 +r_2976 PC (1-16:0, 2-18:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane -8.463548065373898e-11 1.435450036304904e-09 -1696.038145252135 -4.600019212998332 67.6738342747236 -1471.164165651674 3.8000115901431593 61.53297264113682 1619.2838148374876 -1.8001487997013454 42.39237977033677 -2354.937535017656 -1.6000968197338563 39.9719633107541 -2498.09654127071 0.9999454817069156 58.30670794527026 5830.988690077404 -2.200109575706115 46.857159779662254 -2129.764821582746 2.999587331170537 61.577094749176645 2052.8522076784225 2.9992378701559668 70.65383616010857 2355.726328450048 +r_2977 PC (1-16:1, 2-18:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane 2.7999910347270807 52.84598346361279 1887.3625953864444 6.20001297092551 78.50337967196103 1266.180894138394 -0.6000240912095761 61.64733387978554 -10274.14311907243 -3.045774283694154e-11 8.547340016126157e-10 -2806.294629869708 -0.8001348321980754 28.275763639565685 -3533.874854802716 -8.849453254693265e-11 8.61874002200958e-10 -973.9290975336442 -1.6001831903258228 77.44998926720837 -4840.070170430819 -1.03372793072548e-10 6.72818928390754e-10 -650.8665465956436 0.3994095068318933 52.91703521895709 13248.817144762965 +r_2978 PC (1-18:0, 2-18:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane 0.7999279473389798 72.11373762950387 9015.029149737253 -0.200124796751112 61.64993955890568 -30805.74749343905 -1.800144344845029 42.39239925235848 -2354.944445080484 -0.2000489227448348 42.43014807572001 -21209.88580870303 -0.4001960645441546 19.99798642405365 -4997.047246537134 0.1996944297135524 46.90838750909297 23490.083111672044 6.8000314111535145 103.70998097218104 1525.1397339440866 -1.8003232310510564 42.39231960875921 -2354.706025984563 -1.8003728698751391 42.39238664011233 -2354.644826604856 +r_2979 PC (1-18:1, 2-18:1) diacylglycerol (1-18:1, 2-16:1) acyltransferase, ER membrane -6.427093733008807e-11 2.1870731162923182e-09 -3402.895938890334 -1.8001303894386775 42.39241311191329 -2354.963471570092 0.9999862841787528 31.609659510271275 3161.009306865741 1.400001758200694 37.39403374193651 2670.9990557437554 2.3997245715887687 59.957949565710905 2498.53463499834 -8.274721690063697e-11 1.181945825732814e-09 -1428.3813643570595 -5.200544693922437 71.93038153378235 -1383.131686529741 -1.5324638314628182e-10 1.3677069024784423e-09 -892.4888629657855 -3.0001669023035844 78.69056332227666 -2622.872856235317 +r_2980 PC (1-16:0, 2-16:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane 3.999999999999988e-11 5.646802393873227e-10 1411.7005984683117 1.5999848754761423 48.96852442923348 3060.561707788697 2.600007359559161 50.92881200624258 1958.7949172143003 0.7999395702009146 60.00058616469693 7500.639848285921 2.0000002294650154 44.6809776444589 2234.048625904944 -0.800032975198955 28.27573901074097 -3534.3216951412865 -7.400113799891673 96.68009767065855 -1306.4677150245152 -2.2004578707856304 46.85714675058374 -2129.427123903732 -4.000367535447899 63.12503630761948 -1577.9809167097374 +r_2981 PC (1-16:1, 2-16:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane -1.0000212082867577 31.61011400521896 -3160.944362307435 -1.400082766341058 37.39407499067943 -2670.847459140161 -2.2001128744282203 46.85706671770023 -2129.757398464283 1.3999993687994756 37.39406114341545 2671.005571629759 -1.4001578100864156 50.97603633439012 -3640.7350633743176 1.0000043462572763 31.61006593071176 3160.9928545829816 0.1998759745911457 64.81347377562601 32426.84565176207 -0.8001925780622577 39.99595213785901 -4998.290815782497 3.9999967771024494 63.12508066814681 1578.128288240119 +r_2982 PC (1-18:0, 2-16:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane 1.999990243746937 69.26003583652627 3463.018684869639 -8.142299583565696e-11 2.1692014020069403e-09 -2664.1139640516617 9.478251212156503e-11 1.636207523377777e-09 1726.2757514584853 2.142133002757506e-05 34.64443273382039 161728672.72584668 -1.600127783621749 66.31975055175539 -4144.653397720928 0.9999309071893564 42.418790937859 4242.172197386251 9.999927322867457 109.09779488988906 1090.9858778714156 -7.58500922909818e-11 1.8420790344812478e-09 -2428.57850115004 -2.2000883135778886 46.857130299066526 -2129.784064116282 +r_2983 PC (1-18:1, 2-16:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane -1.200008833836674 34.623672884477365 -2885.284833593965 -2.468280133871167e-11 1.3713197831698655e-09 -5555.770450654376 2.0000372715207897 44.68101488098799 2234.009111590876 -0.7999999962695575 56.56847261323471 -7071.059109627064 0.8000002612570101 28.275743226205808 3534.466749020457 -0.6000848090526312 50.99169462143916 -8497.414674092654 -3.000131472956545 54.69545585302644 -1823.101965565716 5.225528063335791e-11 1.354639459179118e-09 2592.3494099740124 1.199680235280924 72.10811743596904 6010.611437562259 +r_2984 PC (1-16:0, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane -2.170811515420841e-11 7.707778035320152e-10 -3550.6436098050167 -3.331160281312675e-11 1.6120144445547363e-09 -4839.198082415617 -2.200077965262978 46.857177375154805 -2129.796221542263 1.8000054769528862 42.39235560748973 2355.1237010263453 1.399870678123569 64.79871013296228 4628.9068801569965 3.600006404118275 59.89780265005088 1663.8248915760255 -1.1520000000000031e-10 5.283794062597451e-10 -458.66267904491656 0.1996329093922121 61.64842300501333 30880.891929443715 2.399920085271218 48.93392842443963 2038.9815779598987 +r_2985 PC (1-16:1, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane -1.2000219166176191 34.62367554145269 -2885.2535992878325 -1.0000319992354616 58.3067260084592 -5830.4860297505975 0.7998910148130768 48.98811818795025 6124.349102658452 0.3999896027935601 40.00197535564134 10000.753788664571 5.937765465070394e-11 1.154190214639303e-09 1943.812401195304 -9.027063125919079e-11 7.958260447944391e-10 -881.6001768165472 0.6000004666180919 24.48998879833826 4081.6616254277774 -1.2002765461989968 34.62363322500133 -2884.6379890239887 -0.8004185622532002 28.27574555521264 -3532.6199177110093 +r_2986 PC (1-18:0, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane -2.600025861281685 50.92892426657932 -1958.785296138318 1.7999978563431294 54.7481031591019 3041.564908878725 1.8000195284512956 42.392429825620574 2355.1094394011525 -0.8000210253512763 28.27573792702356 -3534.374351550091 -1.4000537376457085 37.39408799247133 -2670.903765119201 -1.5487486094254765e-11 7.782174761007167e-10 -5024.8146882237015 -1.2002860194958365 34.62362833757688 -2884.61481473558 -5.000374751475493 81.09436740464288 -1621.7657962678466 3.5999733330392 59.8973981476329 1663.8289400067808 +r_2987 PC (1-18:1, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane -6.387295550829309e-11 1.4913945882825075e-09 -2334.939062102534 1.1999988008573004 66.32822452636199 5527.357567272229 7.232754335536285e-11 1.4862506262431612e-09 2054.888853255875 -1.2000616533331905 34.62366058446347 -2885.1568157598986 0.199835260851442 50.99486619840501 25518.45253992223 2.1208108718731097e-12 1.7081297218310455e-09 80541.35069207835 3.000001517394318 54.69544618230376 1823.1806172488225 2.999679474952987 81.19303576981659 2706.723716576056 -5.200392685775924 71.93035040568697 -1383.1715170746688 +r_2988 PC (1-16:0, 2-16:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -2.6000105340438364 50.92892145576042 -1958.796735202064 -2.60006551942952 50.92892854353973 -1958.755583771368 1.785220540116457e-11 1.190733965025049e-09 6669.954430097318 -1.600070162497388 69.27042068455437 -4329.211450105236 1.800006428722146 42.39237948161547 2355.1237820695183 2.0000151165319173 44.68096026983276 2234.031128090212 -2.000438293685473 63.2201611989104 -3160.315486784539 -1.800107004372163 58.28741001882917 -3237.996956695278 1.2000068001931143 34.6236064499338 2885.284187086432 +r_2989 PC (1-16:1, 2-16:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -4.5830028928488073e-11 1.790453356768062e-09 -3906.725347177582 -1.6000313887094797 56.55123919806992 -3534.383112551426 1.3999985902570315 37.3940451378424 2671.0059137257467 4.068133687739238e-11 1.128563066996037e-09 2774.1543263373123 -4.35113504735816e-11 6.592036348524794e-10 -1515.0153412331397 -2.8000780640128142 52.84611808956931 -1887.308742165392 -0.4001847882616078 66.33780157770089 -16576.792402797353 0.6000031803727427 24.48997735708377 4081.64125761296 1.8000031104313137 42.39236488936027 2355.1273130412696 +r_2990 PC (1-18:0, 2-16:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane 1.5999899520554683 66.31978689770293 4145.012711642564 2.599999056923877 50.92891672836713 1958.80520005351 2.599988258961595 50.92868160492071 1958.804291880188 -3.2001762808774488 74.77206986383364 -2336.49847074462 2.000000646752519 44.68102517496087 2234.050536309137 -1.2001069101004176 63.24036814064616 -5269.561203955954 1.1231499012701662e-10 1.4981465690977266e-09 1333.879446905064 -1.4003182767723985 73.47856236096848 -5247.275821488928 -2.200479533366175 46.85712570001561 -2129.405204161845 +r_2991 PC (1-18:1, 2-16:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -0.6000253618076177 58.31221702047952 -9718.292047657778 0.1999337259497073 61.64993214619598 30835.18393575269 -3.4000859913247803 58.21604417163357 -1712.1932892335692 4.199998490259556 64.6775210774711 1539.9415315855051 -1.6001249561839952 52.895335853036045 -3305.700323503592 -3.2170186816327804e-11 1.6097543135375354e-09 -5003.869958008803 2.0000185154138843 44.6810196785918 2234.0303019317544 -0.200078215044338 78.74750566989478 -39358.36075528965 -4.373958890173823e-11 1.4048822192717316e-09 -3211.923693265212 +r_2992 PC (1-16:0, 2-18:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -2.0000836652530425 44.68104894570762 -2233.958994913083 -1.8000839960696773 58.28751089744973 -3238.0439482110446 2.000013903664553 44.68103703610329 2234.0363211593603 0.999867370217042 58.30667672005239 5831.44109477197 1.742932596856811e-11 9.23189972762741e-10 5296.762332792522 -2.000068125286052 63.220150347483504 -3160.899848770986 1.400001742026243 37.39403554896991 2670.9992156759017 0.799893842995298 56.568417681338325 7071.990636846401 1.200013353694049 34.62357006831454 2885.265398233397 +r_2993 PC (1-16:1, 2-18:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane -1.2712894393827422e-10 7.211326610039101e-10 -567.2450652575595 1.1999794611049053 69.27851809276424 5773.308655547708 0.6000162723084029 24.489979773267603 4081.552601740104 -0.600101720247535 58.31221463339595 -9717.055070154243 -1.5912568074528817e-11 1.1870176352483523e-09 -7459.623297061689 -1.2001085596681942 44.70966764439232 -3725.4686073361263 -3.600137916779065 69.19440215933838 -1921.9930946768984 0.9997282125725168 73.48510806028787 7350.508581846941 -1.5627915167570268e-10 6.84111948014016e-10 -437.7499753989114 +r_2994 PC (1-18:0, 2-18:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane 2.4000095390495324 48.93583866434563 2038.9851735224984 -4.400031986974614 66.19298697983108 -1504.375131266812 1.800014577963145 42.39243070846028 2355.1159655846 1.0000218728913548 31.61010100082054 3160.940961163831 -1.600182766258602 39.97194047870804 -2497.9609405597275 0.6000023266122801 24.48999692124683 4081.650326178185 1.1996884673033223 82.46150127881842 6873.576226349546 -1.3862645137772287e-10 8.848361584936383e-10 -638.288111467759 -1.800672660503535 42.39235557697141 -2354.251081099711 +r_2995 PC (1-18:1, 2-18:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane 1.8000000622354688 42.39241054891215 2355.1338379546423 -3.0813282674009184e-05 60.005958396849415 -194740557.2839666 -4.000125850335334 66.21834350528016 -1655.4065042660848 2.399938974574132 79.97188608803702 3332.2466502394304 1.7999981389330406 42.39235099611621 2355.133045928844 1.799998852550659 42.39239293427711 2355.134442125097 -0.0001696066177871 74.84056626543948 -44125970.57937133 3.1995278682069364 66.26180994438111 2070.987116655909 1.8000056566857432 42.39234419177809 2355.1228316600354 +r_2996 PC (1-16:0, 2-16:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane 1.400000005537529 37.39408722950115 2671.006220113815 -2.0000696948721663 44.6810449243718 -2233.974397938546 0.1998822672797961 76.16502008473438 38104.941034173 -1.1620000000000027e-10 6.089102678908043e-10 -524.0191634172143 2.800003920194002 52.84611225552676 1887.3585095504168 -1.400163031613945 37.39408478446308 -2670.69505051562 1.200002824938514 34.62359262542999 2885.2925931406908 2.0000197541915123 44.68093310042992 2234.0245893467054 1.599718570934937 74.82332293486216 4677.280385082517 +r_2997 PC (1-16:1, 2-16:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane -1.0424858773678283e-10 1.1501808063330802e-09 -1103.3058876895009 0.9999828643687516 54.768562757455726 5476.95012674331 -3.400065430148357 76.08933494528867 -2237.8785499421588 -0.4000738562031327 52.91836810335993 -13227.149758191465 -2.0002072365756094 44.68105420683803 -2233.8212456091696 -1.0000368997864764 31.61009524966264 -3160.892888693597 -4.400205441253984 66.19290850011889 -1504.3140458745268 2.400002457825373 48.93581151126451 2038.990058185396 -0.8001730917806753 60.00050643109799 -7498.440905776412 +r_2998 PC (1-18:0, 2-16:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane -4.000044973548092 77.36390564378563 -1934.075895530816 -1.7052048622741956e-11 6.165739891782262e-10 -3615.835274806305 2.8000113569574894 52.84612416927592 1887.3539222604747 -4.453343391957676e-11 1.298398003516476e-09 -2915.557793861713 3.6000017901864485 59.89779356167748 1663.8267715576692 1.1999311301047897 69.27841848077556 5773.532892235698 5.999947206044486 77.23381381242949 1287.241556636071 -3.0003173800430645 54.69541601404084 -1822.987673832552 -1.8000859755559966 78.72719108988356 -4373.523940464394 +r_2999 PC (1-18:1, 2-16:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane 2.9999984001873696 54.69546872058522 1823.1832629367111 -1.4000284126978924 37.39365520705628 -2670.921166163885 -1.3907231147601312e-10 1.357555285756838e-09 -976.1506595732296 -2.400226643721614 48.935801143070215 -2038.7991805304675 -0.6003193322803374 61.64731253769305 -10269.086671509182 -1.8001946978438896 42.39236124749439 -2354.8764640995846 -0.8003549092510163 66.33422774294381 -8288.101562970402 3.399271274173695 64.72453671747724 1904.0709463004143 4.199539261438805 85.9289928671012 2046.1528638658567 +r_3000 PC (1-16:0, 2-18:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane -1.4000152543071782 37.394087214314354 -2670.977126804198 -1.600085807812354 39.97194287657252 -2498.112456307726 -2.3056733096924155e-11 8.77680544541072e-10 -3806.612761884109 -1.1583770950002656e-10 8.954077867891732e-10 -772.9847134010951 -2.400383636668835 63.205579349125856 -2633.1449016558145 3.399998023248802 58.216001085495336 1712.236321533745 2.800007329762276 52.84601802881664 1887.3528460835607 -0.4000225681832056 52.91870968304588 -13228.931038413244 -1.8011214026380806 42.39232548918406 -2353.662858433226 +r_3001 PC (1-16:1, 2-18:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane -2.2000540812136182 46.85719314694657 -2129.820059745926 -1.800082777364373 42.392407434919576 -2355.025444829224 -1.6001182290150813 39.9719532437344 -2498.0624880661653 2.200004410171696 46.856751323578 2129.848063346434 1.2000022060599436 34.623655759623894 2885.2993423492376 -1.400288314211858 37.39408138668629 -2670.4558630651195 -5.907602740378539e-11 1.728521896224266e-09 -2925.927778470609 -1.600485220988643 39.97186998538712 -2497.484479156634 1.0000101404473518 31.610079577632245 3160.975904053489 +r_3002 PC (1-18:0, 2-18:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane 8.615335691329427e-12 1.076203272409754e-09 12491.71606270499 -3.2743817880923275e-11 8.147960134068859e-10 -2488.3964856205434 -2.119999671210869e-11 6.375200134768925e-10 -3007.1703412706843 2.20002061414748 46.857165586500514 2129.8512061741712 0.4000037880768522 19.997976855410545 4999.446868130248 -1.8002316944221015 50.963458950057095 -2830.938879032293 -5.600217294980974 74.63065260125393 -1332.6385150829667 2.399797519337395 69.24728419444533 2885.54695287647 0.800006913667065 28.27575686220236 3534.4390628566166 +r_3003 PC (1-18:1, 2-18:1) diacylglycerol (1-18:0, 2-18:1) acyltransferase, ER membrane -0.400033729409822 19.997989210774467 -4999.075763005762 -2.600154847375346 50.92890185315412 -1958.6872645128376 -0.0001535984867874 66.33886337979645 -43189789.67000054 -2.20018080518594 46.857181717475 -2129.6968688677853 -1.5879999999999887e-10 7.816039540254174e-10 -492.19392570870457 -1.800315846779598 42.39237395579551 -2354.7187029224297 2.1997378512166907 73.45900482790982 3339.4435972122365 -2.600591975684103 50.92884705236667 -1958.3559254415327 -1.6839782063561074e-10 1.329865089212691e-09 -789.7163301717144 +r_3004 PC (1-16:0, 2-16:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane -2.600037257469567 64.76165632767723 -2490.7972430635546 1.7999663253585827 78.72731721309972 4373.821671214652 -3.2000437115005544 56.483522341612826 -1765.0859623766437 -7.890059934358693e-11 1.2900890883926124e-09 -1635.0814811617422 3.6000253725315305 59.89781143235965 1663.8163688896343 -1.200159107256081 34.62364240963511 -2884.92102424611 -2.1961847534371265e-11 8.734197581024158e-10 -3976.986711775843 -0.800644987015159 60.00046705114875 -7494.016452264721 2.0000190652219336 44.681022823284806 2234.02984502684 +r_3005 PC (1-16:1, 2-16:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane -1.1660864739918343e-10 1.8187279983058127e-09 -1559.6853568499148 -1.6000577493134036 87.17176271208461 -5448.038531702412 0.5999257309141477 73.48949369066793 12249.765246555931 4.199951917050968 64.676694386365 1539.938924628887 -1.200103998246626 34.62366084075857 -2885.0550361755627 -0.4001274547063213 19.997970066947232 -4997.900002044348 -1.800321330842871 42.39238270365407 -2354.712015982552 1.3359627651955236e-11 7.790215443449369e-10 5831.16210002248 -4.400924612357955 79.88668528028329 -1815.225033756738 +r_3006 PC (1-18:0, 2-16:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane 1.9999907291657568 44.68087059525737 2234.0538855345 2.399852215009473 63.20628918227492 2633.757561693248 0.1998946725985399 67.82974966409301 33932.745071360376 2.199817240452572 73.45902458766452 3339.32397822974 -3.2002154152306583 56.48352247668055 -1764.9912630212566 -2.800246625879549 52.84607088665869 -1887.1934492577025 -1.0005158007526822 31.61004776063245 -3159.375167973599 5.999995787011701 77.2344412781624 1287.2415918250006 1.024268282390566e-11 8.222842157502702e-10 8028.015998221874 +r_3007 PC (1-18:1, 2-16:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane -0.6000435671624398 64.81092344694348 -10801.036290319616 0.3998731481204276 82.46894220889278 20623.775964085504 -0.0001549861669093 72.11812824124192 -46531977.452825256 -1.6020965640274624e-10 1.9414611287979204e-09 -1211.8252871832765 -2.0003389457771803 44.68102661596772 -2233.672783819547 -1.600202694197158 72.10034770494534 -4505.700931913441 -2.5483313083923737e-11 1.8176843394639398e-09 -7132.841532330561 -4.400565562075528 66.19281139373409 -1504.1887334707549 1.6000045653627517 39.97188540903876 2498.235709719764 +r_3008 PC (1-16:0, 2-18:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane -1.400102886502286 37.3938370096052 -2670.7920803607417 1.3999134156329398 50.97603802377776 3641.370777258397 -2.4001604015828164 82.43529516474268 -3434.574418875492 1.0000338438425744 31.61008742588145 3160.9017655263992 -2.200541107312913 46.85713802553169 -2129.34618080137 0.1995812805556668 78.74758404410775 39456.39782692125 3.599611607968135 74.75374531370315 2076.7169754711185 -4.6008300608124 67.6736957951071 -1470.9018785874805 -1.1345713837947671e-10 6.414808194827161e-10 -565.3948518754054 +r_3009 PC (1-16:1, 2-18:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane 4.199989495085555 64.67744260966846 1539.9429614133107 -6.314531677093715e-11 7.127048955203222e-10 -1128.6741946448626 0.9999304317512804 76.1586799493634 7616.397854396624 -3.400115628313704 58.21604332806095 -1712.178340150548 1.8000171781105596 42.3923886350525 2355.11022620078 2.199937534423071 67.79430302227809 3081.6467268493147 -0.4003846164868459 74.83943477846069 -18691.88567611199 1.999501363970688 87.16261740996796 4359.217702001315 -2.601102519531142 61.59390569322724 -2367.99223524376 +r_3010 PC (1-18:0, 2-18:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane 1.400000292217565 37.39409510551856 2671.0062357406555 2.6000012866469104 50.928921425168525 1958.8037008569704 -2.800134322069984 52.84614535242426 -1887.271797495701 -0.2000413189368224 67.82972532367202 -33907.857478731275 3.2000076946544342 56.48353089252835 1765.106096053558 -1.2867303551692307e-11 8.407809156657406e-10 -6534.243264628362 -1.200218906918305 93.80978673465944 -7816.056403871064 -2.2007496327180585 83.64426891650332 -3800.717158961768 1.5999186308551885 39.96973911810475 2498.235744447836 +r_3011 PC (1-18:1, 2-18:1) diacylglycerol (1-18:1, 2-18:1) acyltransferase, ER membrane -3.800052767421936 61.533005691924046 -1619.267138063185 -1.1919475589463323e-10 2.035265900627582e-09 -1707.5129567165973 2.200005956379845 46.85718538046167 2129.866296251585 1.9999058934819045 79.98269213884625 3999.322788113477 -1.437195381208862e-10 1.488946097006743e-09 -1036.008128382901 -2.6002468807775783 67.78013023126023 -2606.6805706922432 -3.515616111048118e-11 1.1552686796872227e-09 -3286.105886409765 -1.0156103015442058e-10 1.2263921361124101e-09 -1207.5420407293198 0.800019221493224 28.27575612936959 3534.3845959842456 +r_3022 PC phospholipase B (1-16:0, 2-16:1), ER membrane 8.326182498480481e-05 0.001817102456976 2182.395662487196 0.0002463910457861 0.0042878719965777 1740.2710325357675 0.0002624281871071 0.0037745777317503 1438.327861560656 0.0003475148764043 0.0052839654735584 1520.50051158376 0.0004734461412059 0.0092280152954987 1949.1161702140723 0.0006299472002126 0.0094213605012675 1495.5793911120402 0.0004464378503506 0.0104635840783936 2343.7941183023327 0.0004902704763197 0.0129647487470622 2644.4073982148525 0.0009280052469794 0.019424774507323 2093.1750731527627 +r_3023 PC phospholipase B (1-16:1, 2-16:1), ER membrane 6.106197500279851e-05 0.0016278887188521 2665.9614576461418 0.0002045056981645 0.0038484538730895 1881.832099364211 0.0002023041675521 0.0031188919122676 1541.6844595969071 0.0002439161394368 0.004439063969513 1819.9139998533549 0.0003502149346347 0.008083826449283 2308.2472075935307 0.0002802688869314 0.006291330484807 2244.748089482682 0.0009879431963616 0.0163285592819374 1652.7832108233704 0.0003467197180673 0.0114331874122922 3297.53019990383 0.0009776967873258 0.0199020122266516 2035.6016798508065 +r_3024 PC phospholipase B (1-18:0, 2-16:1), ER membrane 0.0001156681281681 0.002220320035671 1919.5607907156173 9.65612993292938e-05 0.0026048643298884 2697.6276706937474 0.0001857619871142 0.0031275436656422 1683.6295273467758 0.0005043437259916 0.0065791080106099 1304.488917290155 0.000479639225992 0.0093108866537733 1941.2271034580488 0.0003342605173594 0.0070673860397852 2114.3346799123046 0.0004898183015068 0.0115451688443359 2357.030925308153 0.0006890638224003 0.0160647736585209 2331.391249443108 0.0007848511937776 0.0176298477857694 2246.2662891437803 +r_3025 PC phospholipase B (1-18:1, 2-16:1), ER membrane 0.0001039324964759 0.002077959614441 1999.3358043914868 0.0004372186768779 0.0056923155437421 1301.937873374916 0.0002628463395389 0.0037364563504804 1421.5363839702964 0.000538849800881 0.0067562955328954 1253.8365091438914 0.0007512163406105 0.0117727738271417 1567.161573931319 0.0004561663826958 0.0081898750953865 1795.3701557282398 0.0004942031269158 0.0103389716084483 2092.0490068468944 0.0010648279419551 0.0201001368283578 1887.6417528498653 0.0014271763081019 0.0239891944060792 1680.8851345060991 +r_3026 PC phospholipase B (1-16:0, 2-18:1), ER membrane 0.0001844663591388 0.0026849700769042 1455.533729530984 0.000129756934467 0.0030335773208824 2337.892254730887 0.0002461660018061 0.0036497631300561 1482.6430552054248 0.0001499459803168 0.0033058581624752 2204.699422744824 0.0011989832594802 0.0147224366636527 1227.9101102741406 0.000630556360804 0.0089682420347231 1422.2744535139816 0.0007612908549326 0.0142306342206847 1869.276916763036 0.0016832859376845 0.0256282987332442 1522.516059778739 0.0015269810858362 0.022615272615864 1481.044711400513 +r_3027 PC phospholipase B (1-16:1, 2-18:1), ER membrane 8.706363839293968e-05 0.0017187920872752 1974.179024678372 0.0001634176252926 0.0034512349903699 2111.911113742972 0.000277348752988 0.003881088896529 1399.3532888522698 0.0001981396930831 0.0038620455448502 1949.1528853985983 0.0003824833781203 0.0079802278330008 2086.424741440728 0.0003742087574604 0.006648660163145 1776.7248976921512 0.0004172547491273 0.0098823797332141 2368.4283411712745 0.0015136025805537 0.0244642997866155 1616.2961203240363 0.0018359527967725 0.025868025091677 1408.970052887563 +r_3028 PC phospholipase B (1-18:0, 2-18:1), ER membrane 0.0001571577229647 0.0024182329648922 1538.7299582057776 0.0001923825532601 0.0037850212478546 1967.4451678251155 0.0002713485992342 0.0039617218342063 1460.0118981217606 0.0001682410883638 0.0035955945007681 2137.167879579896 0.0006114339558989 0.0103129368338905 1686.6804230276873 0.0003339090516826 0.0064404202328862 1928.7947422904888 0.001071010308254 0.0164335211168875 1534.3942994981353 0.0017850594348001 0.0263585046584875 1476.6177609900187 0.0017499676855627 0.0253024070027576 1445.8785274438433 +r_3029 PC phospholipase B (1-18:1, 2-18:1), ER membrane 0.0001146417399694 0.0020691137589053 1804.852019392434 0.000312380102937 0.0047690358962691 1526.6772279765696 0.0003262090784853 0.0042483620792249 1302.3433004840588 0.0005335277585639 0.0071046274871013 1331.6322108946683 0.0007596858870167 0.0113320833925706 1491.6801254622883 0.0004659232420866 0.0076689210681995 1645.9623335925037 0.0013018637203706 0.0181729364649597 1395.916959709528 0.0019455157897761 0.0271061805270221 1393.264483869405 0.0009010381116486 0.0176473874739022 1958.561712957132 +r_3030 LPC phospholipase B (16:0), ER membrane 5.766910881070633e-06 0.0002189759206355 3797.109495038495 2.120900947924882e-05 0.0006448008558606 3040.2214516029094 2.283298870070037e-05 0.0005746913939576 2516.9346049738265 1.5119289660961194e-05 0.0004509869308125 2982.8579313285904 3.0115618783862923e-05 0.0011366443965501 3774.2687763043286 4.905150730641459e-05 0.0013247987630194 2700.8319127558407 5.166595839795519e-05 0.001951448953201 3777.049751347148 0.0001056194373932 0.0032888845494096 3113.9008411518303 0.0001431686513069 0.0034338319247294 2398.4523800304705 +r_3031 LPC phospholipase B (16:1), ER membrane 5.038512841609895e-06 0.000247154349221 4905.303548697834 1.7904790991021082e-05 0.0006313265541509 3526.0202393179443 5.464973148636028e-05 0.0008963392634921 1640.1530970299702 1.729846921655829e-05 0.0006269109643822 3624.08347544532 3.927954520064361e-05 0.0013575269145273 3456.065765509714 2.25096425651184e-05 0.0009354430466622 4155.743672766469 1.9375641548936707e-05 0.0011988697981519 6187.510205140929 5.808050555437268e-05 0.002594331670412 4466.785620492515 4.288563474405878e-05 0.0021520057155811 5018.010642548115 +r_3032 LPC phospholipase B (18:0), ER membrane 1.2013944501965737e-05 0.000365545647855 3042.6780129976664 3.6121149235984883e-12 6.714144563643184e-10 18587.84868603896 1.86956583989135e-05 0.0005195477186105 2778.975244010211 2.316818110328001e-05 0.0007056282103097 3045.678066673186 6.72394987245933e-06 0.0001530266066044 2275.8439534362183 2.101272525727192e-05 0.0009245385688333 4399.898430658708 8.380045979281269e-05 0.0023794784211116 2839.45747671872 0.000104000225264 0.0034664368610996 3333.105146934932 5.678366364811157e-05 0.0024670466380528 4344.641538702223 +r_3033 LPC phospholipase B (18:1), ER membrane 9.368052932351337e-06 0.0003076103066228 3283.6098263336376 1.714512456848602e-05 0.0006020290091637 3511.3714499941934 2.770293736456223e-05 0.0006571982219909 2372.305194003307 1.4565594915861473e-05 0.0005551442921452 3811.339635298783 5.450477390460711e-05 0.0016742483632021 3071.7462770001434 3.814802866244965e-05 0.0012630886076586 3311.019342139494 0.0001374779743405 0.0033342019874877 2425.262667333523 5.923517984944048e-05 0.0025832732010903 4361.045594284243 6.18573447295559e-05 0.0024730678878135 3998.0181797746495 +r_3034 PC phospholipase B (1-16:0, 2-16:1), cell envelope 1.0045693747556565e-05 0.00034560559271 3440.335743802274 2.247917367006053e-05 0.0007079911481385 3149.5425878644182 7.662926695053642e-06 0.0003732477658866 4870.825217831496 3.3813061097588234e-05 0.0009629321874557 2847.811337390183 5.5811400782620576e-05 0.0017642089546139 3161.0189493098565 2.810458146894222e-05 0.0011179821847267 3977.935718282233 1.8150615339904845e-05 0.0011874522435339 6542.214802620601 7.672295637766568e-05 0.0031182907325608 4064.3516357884 0.0001241715248901 0.0038667682513659 3114.0539304696413 +r_3035 PC phospholipase B (1-16:1, 2-16:1), cell envelope 1.7045433716816697e-05 0.000453165419193 2658.5737079014075 8.958523838896425e-06 0.0004478937115421 4999.637435772884 1.4786178548223124e-05 0.0005230733241134 3537.5829015423888 2.795431862943293e-05 0.0008836475140125 3161.041146186845 8.892007349964659e-05 0.0022112290151875 2486.7602197791552 1.862584108856019e-05 0.0009123227460145 4898.155963409799 9.872023206787566e-05 0.0028501431399658 2887.091207409472 2.568431863406697e-05 0.0018006998375403 7010.891988981762 7.339226298544816e-05 0.0029954858027147 4081.473551658569 +r_3036 PC phospholipase B (1-18:0, 2-16:1), cell envelope 4.938437513446623e-06 0.0002355072773476 4768.862149340783 7.968827824321208e-06 0.0003941064131761 4945.600806849796 4.123897581783443e-06 0.0002682419633456 6504.573841274113 2.7320753950997828e-05 0.0008639717938791 3162.3277872518124 4.5440446788226206e-05 0.0015790835078565 3475.061579424577 1.898436166417409e-05 0.000912335520825 4805.721345620736 4.933276353555521e-05 0.002002643684614 4059.4597607949854 0.0001283084657786 0.0040249596266828 3136.9400313981537 4.858991884088271e-05 0.0023572253420253 4851.26420923763 +r_3037 PC phospholipase B (1-18:1, 2-16:1), cell envelope 7.382189823299462e-06 0.0003013159453984 4081.6607620612417 1.3481465089436864e-05 0.0005485089900697 4068.615587630024 7.560678226021719e-06 0.0003779921975873 4999.448280796175 1.1181807771541005e-05 0.0005590357150818 4999.511049587368 1.184550466304922e-05 0.0007897823573358 6667.359304660931 7.283813002973344e-05 0.0018196951100861 2498.272689514862 3.441812035553462e-05 0.0016193598835054 4704.963161200308 0.0001485932905702 0.0042959300990643 2891.0659980530013 2.439721063196346e-05 0.0017251320485994 7071.021661547249 +r_3038 PC phospholipase B (1-16:0, 2-18:1), cell envelope 1.4567851814993171e-05 0.0004182103993535 2870.7760393546378 8.876743099318537e-06 0.000443812694356 4999.724441615719 1.497709495631741e-05 0.0005269424110886 3518.321895037137 2.191611728421881e-05 0.0007746759785682 3534.731852918681 3.301660512401302e-05 0.0013479043068593 4082.504248382063 4.177041795938396e-05 0.0013309694732776 3186.392519633976 6.571600667990281e-05 0.0023236199035828 3535.850732533107 0.00010002121187 0.0035362453830035 3535.4954383041827 0.0001403444591171 0.0040499199203353 2885.699902804694 +r_3039 PC phospholipase B (1-16:1, 2-18:1), cell envelope 9.836321893441554e-06 0.0003449167973145 3506.562727929473 8.95890118718156e-06 0.0004478945259673 4999.435942079321 1.4399409273880898e-05 0.0005015857335321 3483.377157991722 1.6772765292489215e-05 0.0006846081472593 4081.665338546702 1.1162340932558771e-05 0.0007892938312281 7071.042140684449 1.7796194905548807e-05 0.0008899893297044 5001.009116993505 1.5749731539540908e-11 1.484318797821987e-09 9424.40697541727 2.683195696913786e-05 0.0018025449761658 6717.90349932033 4.892583642319856e-05 0.0024460479885518 4999.501628125621 +r_3040 PC phospholipase B (1-18:0, 2-18:1), cell envelope 1.7241770211406402e-05 0.000454044415189 2633.397903010528 2.428135566008917e-05 0.0007121747337591 2933.010593513639 2.0048907150969507e-05 0.000601277385415 2999.0531697684355 6.176022315128822e-06 0.0003964117667449 6418.561114552611 2.2305920399712643e-05 0.0011151889999356 4999.520216838817 3.30904840219154e-05 0.0011761857457186 3554.4531320233828 8.404704177528579e-05 0.0026383538444876 3139.1394494785086 0.0001008782181697 0.003565572467563 3534.531569107748 0.0001704700221375 0.004513060840825 2647.4219831935707 +r_3041 PC phospholipase B (1-18:1, 2-18:1), cell envelope 1.4619599899386838e-11 2.1688057949005502e-09 14834.918943243529 1.3394892421963633e-05 0.0005467448851047 4081.741516701004 3.7848338923572826e-06 0.0002676180171621 7070.799532380556 1.1015213827011424e-05 0.0005507675669902 5000.062419484757 6.695140542898252e-05 0.0019086459391587 2850.7929399380773 1.82401986391242e-05 0.0009119221000795 4999.518470832492 8.331644329463275e-05 0.0026337349516652 3161.122639803025 5.109203980355991e-05 0.0024910851169945 4875.681469309768 1.4807203842638257e-06 0.0001046949059915 7070.538577317388 +r_3042 LPC phospholipase B (16:0), cell envelope 2.4613545562549763e-05 0.0005497368505903 2233.4728216757408 3.135591676937907e-05 0.0008375147509377 2670.9943041935376 2.264002165137105e-05 0.0006512415983365 2876.506075678388 5.5729178381806974e-05 0.0012450837469373 2234.168496809973 8.882800590663318e-05 0.002219368095472 2498.5004141653785 6.987499942832592e-05 0.0017553523882457 2512.13223986691 8.386662201980699e-05 0.0026510403408623 3161.0195772953475 0.0001767441682477 0.0047218384852325 2671.5667804177097 0.0002645159840073 0.0056359613051103 2130.669466445084 +r_3043 LPC phospholipase B (16:1), cell envelope 2.6881755610258352e-05 0.000572674316647 2130.345669940382 1.7917425026078105e-05 0.0006332916139509 3534.5012635980866 2.918558782210396e-05 0.000732704174109 2510.4999720242063 4.472708392191436e-05 0.0011174003262521 2498.2633077599285 0.0001000824144322 0.0023474529675267 2345.5199206019174 3.642203599410886e-05 0.0012873442595982 3534.520310194878 9.872024781760712e-05 0.00285014313942 2887.090746252903 5.251627560320452e-05 0.0025476322894013 4851.129026457232 0.0001223180994086 0.003866381119892 3160.9231492185263 +r_3044 LPC phospholipase B (18:0), cell envelope 2.2180207724853043e-05 0.0005215303543011 2351.332146076936 3.225018348441039e-05 0.0008160622137015 2530.411072222439 2.4172804732753005e-05 0.000663289770228 2743.950392025786 3.349677626612669e-05 0.0009664951921315 2885.337933575682 6.77463671879383e-05 0.001932646947221 2852.768388096205 5.207484568608934e-05 0.0015080231317561 2895.876333165992 0.0001333798053108 0.0033324038387306 2498.432075953721 0.0002291866839483 0.0053976610375433 2355.137281343531 0.0002190599409784 0.0051594758476048 2355.2803970271766 +r_3045 LPC phospholipase B (18:1), cell envelope 7.382204442899429e-06 0.0003013159450377 4081.652673919317 2.6876357511400307e-05 0.0007754654512013 2885.307098897073 1.1345512118381146e-05 0.0004630769496154 4081.587016818889 2.219702159855243e-05 0.0007846141716635 3534.7723034821543 7.879691009203129e-05 0.0020831278847203 2643.666969031336 9.107832866885694e-05 0.0020347562739312 2234.0729168726943 0.0001177345636501 0.0031056664517819 2637.854471530096 0.0001996853303738 0.0049644066593344 2486.114853825912 2.5877931016227057e-05 0.0017282850873309 6678.606130633703 +r_3046 PE phospholipase B (1-16:0, 2-16:1), cell envelope 3.5162796011112227e-10 7.382594019216151e-10 209.95469236527973 2.9014550561169475e-10 1.258664281356949e-09 433.8045073982413 3.6539781461265545e-10 1.082032467908405e-09 296.12450448162286 3.14296674921637e-10 7.208562497750211e-10 229.3553534903768 3.4850000000002356e-10 7.390506600122014e-10 212.06618651711668 3.3059970950642363e-10 1.0741004214689676e-09 324.89454484777684 3.8830000000091175e-10 7.35544532704295e-10 189.42686909672105 2.501525730090978e-10 1.1061606927076244e-09 442.1944093564826 3.387121021950538e-10 6.810373478747734e-10 201.0667299636625 +r_3047 PE phospholipase B (1-16:1, 2-16:1), cell envelope 3.2221219535564473e-10 7.509198092901626e-10 233.05133080432543 2.6146646860987937e-10 1.451705790167057e-09 555.2168115036854 3.664278953193351e-10 9.73117968597596e-10 265.5687465468593 2.0680057920772855e-10 9.834069096350739e-10 475.533924229126 3.0675945397664956e-10 8.360043039902796e-10 272.5276411705688 3.346166666668341e-10 6.979772033377393e-10 208.5900891579589 3.2946805872063107e-10 7.608268732915013e-10 230.9258373166415 4.0314231018892337e-10 6.704863066376394e-10 166.3150430237479 3.014921473369184e-10 6.951907340962386e-10 230.58336352600287 +r_3048 PE phospholipase B (1-18:0, 2-16:1), cell envelope 2.9960000000000634e-10 8.217916858800816e-10 274.296290347151 2.483771614261318e-10 1.8700512593483744e-09 752.9078956418198 2.9096919185392004e-10 9.410976588039224e-10 323.4354994106719 2.809878560287416e-10 7.82446223165141e-10 278.4626475405778 3.3662222165679803e-10 8.225447751902102e-10 244.35248841914924 2.0185653403573727e-10 1.1016419968514786e-09 545.7549353623801 3.690343110955329e-10 7.760560745287014e-10 210.29374537691743 3.9991972449240006e-10 1.0293478218111367e-09 257.3886104561712 3.1953092002761056e-10 1.5732071373256e-09 492.3489523923567 +r_3049 PE phospholipase B (1-18:1, 2-16:1), cell envelope 2.236533307635482e-10 2.0116731624966432e-09 899.4604084941768 3.3409065468770505e-10 7.014970571917371e-10 209.97206816439365 3.5680309844972845e-10 1.580040192627226e-09 442.8325313015308 3.8790000000001285e-10 6.400511878784509e-10 165.00417320918527 3.351439653744035e-10 1.2030576909624383e-09 358.9674334784611 3.507886443988448e-10 6.83219807920035e-10 194.76679728070613 4.049000000028428e-10 7.586969844080267e-10 187.37885512538904 3.99498214423485e-10 1.074247427566951e-09 268.89918121841805 3.148075838936103e-10 1.3831365720265864e-09 439.3593556164199 +r_3050 PE phospholipase B (1-16:0, 2-18:1), cell envelope -3.967047840222416e-10 1.7795534201447943e-09 -448.58380635133005 -5.556857072221853e-10 1.5939906913189442e-09 -286.8511229642988 -4.316663079542811e-10 1.6154564927327355e-09 -374.2373363324507 -3.989082501792825e-10 1.2034387277613542e-09 -301.6830880836608 -5.596011138080919e-10 1.2872010535330034e-09 -230.0211743278325 -3.4382498926566747e-10 1.1438235473230388e-09 -332.6760948254481 -5.421088686039206e-10 1.369654645497906e-09 -252.65306008092864 -1.460142310188889e-09 1.6055484079933395e-09 -109.95835109973903 -3.2173333333333845e-10 1.0116505295928187e-09 -314.4375869020314 +r_3051 PE phospholipase B (1-16:1, 2-18:1), cell envelope -2.3522366705734354e-10 9.326959120461128e-10 -396.51448500662025 -1.302214703415526e-10 1.5386488096335302e-09 -1181.563075273126 -2.1799383528336567e-10 1.0643063104413843e-09 -488.2277102276376 -1.9287150872557902e-10 9.66255729163141e-10 -500.9841710410151 -1.7908527337209474e-10 9.795190262483519e-10 -546.9567697021935 -2.339000000000016e-10 8.972746571491392e-10 -383.6146460663247 -2.3107842558676926e-10 2.0431397111760707e-09 -884.1758835719943 2.729999999999989e-11 8.937921922329663e-10 3273.964074113443 -8.590000000000002e-11 8.028699209847313e-10 -934.6564854304208 +r_3052 PE phospholipase B (1-18:0, 2-18:1), cell envelope -4.4011666666667294e-10 1.2027049179021916e-09 -273.26956895569526 -3.4507602144233236e-10 2.341308399203573e-09 -678.4906089439318 -2.8320293515921475e-10 1.2896016738249582e-09 -455.3631031754501 -5.325442670727517e-10 1.2932704025573144e-09 -242.8474931607213 -4.22748838223621e-10 1.2341967219585292e-09 -291.9456212214775 -4.103714331131763e-10 1.4595007322983601e-09 -355.6535895362493 -4.2658221155982256e-10 1.982973612341254e-09 -464.8514538593619 -1.7521972449238664e-10 1.3197491275366315e-09 -753.1966685599799 -4.939508542954996e-10 1.694786775377697e-09 -343.108380244609 +r_3053 PE phospholipase B (1-18:1, 2-18:1), cell envelope -1.2504836848404835e-10 2.5843966478311714e-09 -2066.717606284361 -1.0309659132937752e-10 1.612692715622878e-09 -1564.254157026954 -4.4673492183874947e-10 1.852158161481652e-09 -414.5989200616367 -6.566108418050534e-11 1.155790014099422e-09 -1760.2359579109325 -1.6559041560411563e-10 1.5446576947708243e-09 -932.81829696213 -2.297651322288248e-10 1.3453757999748658e-09 -585.5439365077361 -2.919328640693697e-10 1.7468555884392751e-09 -598.3757923274386 1.5534921256743186e-10 1.521608569209828e-09 979.4762033630192 -3.7295856582424525e-10 1.903930329477286e-09 -510.4937931294232 +r_3054 LPE phospholipase B (16:0), cell envelope -4.507682391112616e-11 1.69326707014254e-09 -3756.40278800698 -2.655402016104452e-10 1.175585039781217e-09 -442.71452407264223 -6.626849334162766e-11 1.241131075263609e-09 -1872.88259122676 -8.461157525764826e-11 1.1178810421932782e-09 -1321.191620400934 -2.1110111380809256e-10 1.155205668706078e-09 -547.2285995403369 -1.322527975924588e-11 1.0458370817888234e-09 -7907.86358267901 -1.5380886860303256e-10 1.2405129584607803e-09 -806.5288885665217 -1.2099897371797903e-09 1.6573769529194903e-09 -136.9744636663165 1.6978768861710523e-11 8.54740083480182e-10 5034.169970990886 +r_3055 LPE phospholipase B (16:1), cell envelope 8.698852829829563e-11 9.313127878344535e-10 1070.6156386976154 1.3124499826832287e-10 1.0689666655715322e-09 814.4818314417522 1.4843406003595686e-10 8.817668923871056e-10 594.0461994864961 1.3929070482132442e-11 1.1267568720430954e-09 8089.246683678188 1.2767418060454662e-10 9.372618530600803e-10 734.1044591961169 1.0071666666682548e-10 8.487598525307962e-10 842.7203566402031 9.838963313385475e-11 2.0393624052447286e-09 2072.741141813453 4.304423101889266e-10 8.152934669089581e-10 189.40830109175727 2.1559214733691142e-10 7.868094738612994e-10 364.9527515636884 +r_3056 LPE phospholipase B (18:0), cell envelope -1.405166666666672e-10 9.957740102878943e-10 -708.651887288263 -9.669886001620091e-11 1.4637272446250735e-09 -1513.6964845085463 7.76625669470087e-12 1.226687850437707e-09 15795.097930187008 -2.515564110440123e-10 1.1842363354536363e-09 -470.763726727856 -8.612661656682393e-11 1.0613835839241071e-09 -1232.352583014335 -2.0851489907753787e-10 1.0327788839845201e-09 -495.3022007316961 -5.754790046429239e-11 1.887890327542241e-09 -3280.5546550106533 2.2470000000000063e-10 8.85503660831858e-10 394.0826260933936 -1.7441993426791003e-10 1.260561564145236e-09 -722.7164540774373 +r_3057 LPE phospholipase B (18:1), cell envelope 9.860496227949963e-11 1.6995354718888822e-09 1723.5800639236415 2.309940633583234e-10 1.4608048177296944e-09 632.3992904803187 -8.993182338903044e-11 1.1815965399662095e-09 -1313.8803322766123 3.2223891581949997e-10 9.719603654730643e-10 301.6272454247896 1.6955354977029638e-10 1.1019838710441555e-09 649.932645195028 1.2102351216995863e-10 1.1371306680167376e-09 939.594833787186 1.1296713593347192e-10 1.5466290003320904e-09 1369.0964080411177 5.548474269909309e-10 1.0792176038703551e-09 194.5070935487992 -5.815098193071382e-11 1.238588405595307e-09 -2129.95269292455 +r_3058 PS phospholipase B (1-16:0, 2-16:1), cell envelope 2.50419824873413e-10 1.1735300638258007e-09 468.6250636981394 1.766684853956075e-10 1.099153355805469e-09 622.1558719678692 3.852286797446031e-10 7.285020258324441e-10 189.10897971444464 2.8624879740767567e-10 7.83140906401338e-10 273.5874922422778 1.6737207001371275e-10 1.0140789523092742e-09 605.8830199245256 2.2975574508926435e-10 8.506799100783241e-10 370.254032058184 2.4360844816560056e-10 8.222702680134367e-10 337.5376651365031 2.8595469533741184e-10 8.207806882718886e-10 287.03172273615223 1.9516537335307868e-10 8.443676344046232e-10 432.6421331293518 +r_3059 PS phospholipase B (1-16:1, 2-16:1), cell envelope 3.0176268184044665e-11 1.1449519839516552e-09 3794.213310170124 8.558777605216062e-11 1.1252804188179834e-09 1314.7676814644565 1.83518751375172e-10 1.3154014483581392e-09 716.7667818690807 1.5470221669877019e-10 9.248335306966221e-10 597.8153063555773 1.3781624309809528e-10 1.026846965999855e-09 745.0841373385595 1.6572651092962008e-10 9.229100646491143e-10 556.8874041166843 2.4759675155392356e-10 9.728081362124778e-10 392.9002016816089 2.4419130958085e-10 8.05683602955382e-10 329.9395069948736 2.433970349021802e-10 8.232914819789827e-10 338.2504155442398 +r_3060 PS phospholipase B (1-18:0, 2-16:1), cell envelope 2.9670715682500005e-10 7.97720911800418e-10 268.8579946424816 1.6035956967297184e-10 1.010740365314217e-09 630.2962569527115 2.7588704842307137e-10 9.452276623896336e-10 342.6140037353735 1.8882211975935983e-10 8.28565189218026e-10 438.807270183161 2.0870278691754992e-10 1.2851465889056427e-09 615.7783553764199 2.332072575322308e-10 8.18573178709837e-10 351.0067342551313 2.7994529263934087e-10 9.293385630127615e-10 331.9714913763695 2.733652295443032e-10 7.491978338393146e-10 274.0647869109832 2.2419795696504248e-10 1.093587553482449e-09 487.7776623330085 +r_3061 PS phospholipase B (1-18:1, 2-16:1), cell envelope 3.418000000000105e-10 6.837150380462888e-10 200.0336565378197 2.968022555163625e-10 1.0744728767084284e-09 362.0164121863264 4.0390000000001445e-10 6.486901801244934e-10 160.60663038486518 3.4859999999995747e-10 6.150233253608917e-10 176.42665673005362 2.3316864924430456e-10 7.09684108052733e-10 304.36514958284755 1.5179999999999874e-10 7.319589556679542e-10 482.1864003082741 3.3663333333334307e-10 7.63631792476344e-10 226.84378427853903 1.7526714588749594e-10 6.675789738381181e-10 380.8922490622614 -5.6300000000000067e-11 1.2192528964596035e-09 -2165.635695310128 +r_3062 PS phospholipase B (1-16:0, 2-18:1), cell envelope -3.984745769047688e-10 1.1700507585995183e-09 -293.6324740434189 -4.657749628282385e-10 1.405536084083401e-09 -301.7629104726511 -4.85283505865074e-10 1.0725944144467395e-09 -221.0242881704203 -4.029692350718008e-10 1.1204744561046386e-09 -278.05459042177074 -2.699247890777134e-10 1.0969126233774618e-09 -406.3771345808674 -1.8819670642422108e-10 1.0516183102200715e-09 -558.7867769851296 -3.890833333333493e-10 1.2889479100580166e-09 -331.27810924599623 -3.5070623087214887e-10 1.078118249211635e-09 -307.41348579137923 -1.0959867026003844e-10 1.026434853307461e-09 -936.5395135471064 +r_3063 PS phospholipase B (1-16:1, 2-18:1), cell envelope -9.671159457296955e-12 8.640470675175423e-10 -8934.265548332087 -7.662425422724244e-11 1.1049531463639167e-09 -1442.0409797229315 -6.214199996901273e-10 1.642635786216618e-09 -264.33584162655245 -4.2820994313325175e-10 1.159140311558535e-09 -270.6943942209744 -1.6524951187466456e-10 1.224673728749018e-09 -741.1058071250983 -2.6482170809002227e-10 1.0380729594845871e-09 -391.989375407136 -2.7899034513096086e-10 1.0668337818115183e-09 -382.3909323137099 -1.5682938175258514e-10 9.191806788895111e-10 -586.1023416770307 -4.0319348092249004e-10 1.7994663180289503e-09 -446.3034258172642 +r_3064 PS phospholipase B (1-18:0, 2-18:1), cell envelope -4.411077456686096e-10 1.1641954984608503e-09 -263.9254263595439 -2.207613667176772e-10 1.178150599525216e-09 -533.6760761369563 -1.825756399250038e-10 1.3447254779429903e-09 -736.530611912608 -2.0910636233973215e-10 1.089581019706129e-09 -521.0654556440047 -1.9586217589974809e-10 9.988103531734243e-10 -509.9557117575701 -2.455950443824167e-10 9.570617482529155e-10 -389.69098528009073 -3.066531836728218e-10 1.105085970462144e-09 -360.3699649311961 -2.5114451333911157e-10 9.535233157168411e-10 -379.6711714061347 -1.339893371286531e-10 1.843830682302097e-09 -1376.1025480196972 +r_3065 PS phospholipase B (1-18:1, 2-18:1), cell envelope -6.984976785177653e-11 1.3994619306899091e-09 -2003.5312553358983 4.3742497136091615e-11 1.531862006438325e-09 3501.99944386439 4.074466593735402e-11 1.0611137597306775e-09 2604.301042404342 6.191240667902795e-11 1.0860624727993187e-09 1754.1919803405233 -1.1602327242141632e-10 1.4478031253372631e-09 -1247.8557923091455 -8.187605465434858e-11 1.1732612699177243e-09 -1432.9724055107613 -1.3305696355507662e-10 1.3393088319030235e-09 -1006.5680112628152 -2.2009825438624215e-10 1.172084805037391e-09 -532.5279876961421 4.0321123090952636e-11 1.3311326813688847e-09 3301.328384048826 +r_3066 LPS phospholipase B (16:0), cell envelope -1.4805475203135555e-10 1.207372901690027e-09 -815.4908134487474 -2.891064774325573e-10 1.4048542476066746e-09 -485.9297031608012 -1.0005482612046932e-10 9.130090060317075e-10 -912.5087129054768 -1.1672043766412672e-10 1.067483309799857e-09 -914.5641767311 -1.0255271906401494e-10 1.215290485511792e-09 -1185.0397498999414 4.15590386650218e-11 1.0835334543860031e-09 2607.214914472889 -1.4547488516780495e-10 1.1337712477776187e-09 -779.3587508041792 -6.475153553473664e-11 1.0187733441937536e-09 -1573.3578142671563 8.556670309304316e-11 9.637892688145601e-10 1126.3601774706206 +r_3067 LPS phospholipase B (16:1), cell envelope 2.050510872674558e-11 1.2109977477938034e-09 5905.834316373334 8.963521824915345e-12 1.3511278667858155e-09 15073.627232436356 -4.379012483149464e-10 1.5502881472233535e-09 -354.02688464326064 -2.735077264344768e-10 1.2256062960681011e-09 -448.1066447538605 -2.7433268776549222e-11 1.396751767860159e-09 -5091.452204391131 -9.9095197160399e-11 1.099915339283072e-09 -1109.958273257896 -3.1393593577040336e-11 1.178011939348789e-09 -3752.395967215192 8.736192782826381e-11 8.931872353693535e-10 1022.3987239901372 -1.597964460203325e-10 1.8147382264208847e-09 -1135.6561873660053 +r_3068 LPS phospholipase B (18:0), cell envelope -1.444005888436117e-10 1.0926946378155007e-09 -756.7106523359872 -6.040179704471139e-11 1.2396929029361574e-09 -2052.410629469345 9.331140849806827e-11 1.3762399134195279e-09 1474.8892290571507 -2.028424258037075e-11 1.006638335150834e-09 -4962.6616875750005 1.2840611017801872e-11 1.395750215077019e-09 10869.811515526706 -1.2387786850291488e-11 9.052264494432635e-10 -7307.410600320132 -2.670789103348269e-11 1.0548911758761824e-09 -3949.735958386623 2.222071620518844e-11 8.84903868235717e-10 3982.337293111624 9.020861983639028e-11 1.668488825807518e-09 1849.58912888106 +r_3069 LPS phospholipase B (18:1), cell envelope 2.719502321482177e-10 1.349003149920801e-09 496.0478022999333 3.40544752652448e-10 1.286512264355431e-09 377.78067473804697 4.4464466593736864e-10 9.266244434738728e-10 208.3966174474236 4.105124066789847e-10 9.94901263724647e-10 242.3559550302817 1.1714537682276266e-10 1.391796983677259e-09 1188.0938210502368 6.992394534565134e-11 1.0905073403119051e-09 1559.5620855220025 2.0357636977825598e-10 1.182158098577217e-09 580.6951464282786 -4.4831108498718334e-11 1.079062318644217e-09 -2406.949894346392 -1.5978876909046952e-11 1.1832733867229412e-09 -7405.235007805795 +r_3070 PI phospholipase B (1-16:0, 2-16:1), cell envelope 4.499688857532765e-06 0.0001824547232183 4054.829767016393 4.613209501386693e-06 0.0001906591192273 4132.895312255094 1.2066655180057417e-05 0.0003797393351244 3147.014060301245 1.47929479692488e-05 0.0005174804210573 3498.1561628764903 2.211623272775945e-05 0.0008965026790574 4053.595791349304 1.810591033388503e-05 0.000702624831365 3880.637970740769 3.4390874274276565e-05 0.0013831243146545 4021.777125012291 6.984076255043727e-05 0.002422709093879 3468.904126196297 5.133283302812298e-05 0.0020119785305356 3919.476895875573 +r_3071 PI phospholipase B (1-16:1, 2-16:1), cell envelope 4.667928409955535e-06 0.0001894024720149 4057.5273521986 1.4379957464926771e-05 0.0003432818024485 2387.224046286605 1.6748031381305902e-05 0.0004497699005516 2685.5090625976777 1.1279387114574423e-05 0.0004482230123481 3973.8241785226096 0.0001038855966664 0.0019088658640397 1837.4692212331229 3.599123264884397e-05 0.0009815036443141 2727.063154214217 0.00012732950183 0.002596526857119 2039.2185784134915 6.830115033554766e-05 0.0023972353658673 3509.8023299612023 3.33370368944087e-05 0.0016482364687075 4944.160076158313 +r_3072 PI phospholipase B (1-18:0, 2-16:1), cell envelope 6.571243825326732e-06 0.0002116822634535 3221.3423984924334 3.7263331712491306e-06 0.0001776673978725 4767.888154588932 8.590599126331389e-06 0.0002955291882782 3440.146419734367 7.310991958170226e-06 0.0003534715221348 4834.79566325895 8.490030514292399e-06 0.0005325953612931 6273.185477914855 2.34206142250202e-05 0.0008047353770335 3436.0131177682 5.617448648935214e-05 0.0017378273200894 3093.623865024213 0.0001019479350479 0.0029271448110433 2871.2153999650764 1.7641278437641412e-05 0.0011663989830742 6611.759953776608 +r_3073 PI phospholipase B (1-18:1, 2-16:1), cell envelope 2.649173531418706e-08 1.8746205133835304e-06 7076.246577096137 1.819195385956666e-06 0.0001256186249205 6905.174996061436 7.366418822011496e-06 0.0002897807213572 3933.807299841708 4.474692132926907e-07 1.8264018929336007e-05 4081.625816207711 1.51177279619378e-05 0.0007375086241099 4878.435608622993 1.6860235932430894e-05 0.0006790774821205 4027.68671115893 3.419424396396681e-05 0.0013844444286515 4048.7645526261313 9.823493386421257e-07 4.009572979284453e-05 4081.616204706541 1.6551116948509343e-05 0.0011443763434297 6914.194051011327 +r_3074 PI phospholipase B (1-16:0, 2-18:1), cell envelope 1.0270960626443724e-05 0.0002659459045197 2589.299231028917 3.4521241112848774e-06 0.0001726563653467 5001.453012142274 1.2513307068103446e-05 0.000394436036733 3152.132642365248 2.8032180102624e-05 0.0006990729349724 2493.822929266407 7.609979413709928e-06 0.0005318578433944 6988.952459401611 3.872713428806951e-05 0.0010334782733899 2668.615409811772 2.9829676715858102e-05 0.0012369585254681 4146.73795244513 6.680509781097148e-05 0.0023568848025782 3528.0014247522786 0.000175186340414 0.0037296789032995 2128.9781466315053 +r_3075 PI phospholipase B (1-16:1, 2-18:1), cell envelope 6.187117845804478e-06 0.0002186772215207 3534.395609889173 1.5988870107554544e-06 0.0001130380513502 7069.796088773142 1.0200658978005388e-05 0.000360531963846 3534.3987542713835 7.325199621537308e-06 0.0003659137243579 4995.273074635581 7.521301752246407e-06 0.0005318236534589 7070.899040849013 1.14654339871637e-05 0.0005732084977278 4999.448763733025 2.2610405909679897e-05 0.001130399401594 4999.465317472027 3.401491031290548e-05 0.0017005691898162 4999.481621949423 3.2980958420160787e-05 0.0016481401480403 4997.247584633267 +r_3076 PI phospholipase B (1-18:0, 2-18:1), cell envelope 6.204792914807996e-06 0.000216824398182 3494.466312720904 1.1639320857082783e-05 0.0003141895234557 2699.3802070895927 7.54991251350046e-06 0.0003056214490907 4048.013119943854 1.7335194114964946e-05 0.0005431902442771 3133.45348586668 2.330236764037668e-05 0.000922424553979 3958.501420176271 2.8536438891504312e-05 0.0008812557540726 3088.177040671481 6.059316020032691e-05 0.0017791321890466 2936.193100284984 9.526188768935476e-05 0.0027808738728464 2919.188292714418 0.0001291447217356 0.0032053849089819 2482.010000798948 +r_3077 PI phospholipase B (1-18:1, 2-18:1), cell envelope 5.388534082807853e-06 0.0001922682434625 3568.0992364141985 1.588902469289966e-06 0.0001123379923212 7070.162863515583 9.348646135352104e-06 0.0003315648042207 3546.661189441781 2.3914017751643527e-05 0.0006412188024588 2681.3512021199467 3.0084774680946164e-05 0.0010633291363146 3534.4427458454697 2.0534581551930083e-05 0.0007336309374398 3572.6607605056806 4.20960545378851e-05 0.0014905896437603 3540.92482092085 0.0001015761525069 0.0029308690401497 2885.3908794681693 6.476337021598304e-05 0.0022895056586318 3535.1860951591448 +r_3078 LPI phospholipase B (16:0), cell envelope 1.4770649483976494e-05 0.0003229976852454 2186.753436914517 8.065333612671578e-06 0.0002571562585475 3188.414402889609 2.4579962248160865e-05 0.0005494896192624 2235.518564734827 4.282512807187278e-05 0.0008722946408615 2036.8757319243684 2.9726212141469382e-05 0.0010422346844679 3506.113323513532 5.683304462195458e-05 0.001260240988363 2217.444088638913 6.422055099013461e-05 0.0018550060039021 2888.492819358021 0.0001366458603614 0.0033949017557333 2484.4526916177 0.0002265191734422 0.0042710842541681 1885.5288006150336 +r_3079 LPI phospholipase B (16:1), cell envelope 1.0855046255760058e-05 0.0002891972895865 2664.1737195097667 1.5978844475682225e-05 0.0003613505733884 2261.4311938414767 2.6948690359311245e-05 0.0005761378824786 2137.9067954581374 1.8604586736105417e-05 0.0005784735217963 3109.3059469778977 0.0001114068984186 0.0019811725043161 1778.3212102998025 4.745666663600759e-05 0.0011362623050306 2394.315457817109 0.0001499399077396 0.0028308999832646 1888.0230259839764 0.0001023160606484 0.002938371227913 2871.857271761396 6.631799531456922e-05 0.0023304178320975 3514.0052425342483 +r_3080 LPI phospholipase B (18:0), cell envelope 1.277603674013474e-05 0.0003042149243947 2381.1368938783253 1.5365654028331922e-05 0.0003628920071918 2361.708824907339 1.614051163983186e-05 0.0004278705658571 2650.910797655556 2.464618607313518e-05 0.0006478767695574 2628.7100472052507 3.1792398154660646e-05 0.0010649550208916 3349.715915455479 5.1957053116524495e-05 0.0012042480909131 2317.775968187432 0.0001167676466896 0.0024918483428694 2134.0229194579715 0.0001972098227373 0.0040419263070481 2049.556280181881 0.0001467860001732 0.0034278610474331 2335.277917095069 +r_3081 LPI phospholipase B (18:1), cell envelope 5.415025818122041e-06 0.0001933220470117 3570.1038832492954 3.4080978552466424e-06 0.0001705292105718 5003.647718309799 1.671506495736356e-05 0.0004484929284204 2683.1659318374354 2.4361486964936256e-05 0.0006495749267898 2666.400978416512 4.520250264288413e-05 0.0012937070819641 2862.025344448069 3.739481748436109e-05 0.0010061499885617 2690.6134492635747 7.629029850185144e-05 0.0020336332956673 2665.651250031417 0.0001025585018455 0.0029498541251919 2876.264836272603 8.131448716449175e-05 0.0025708251540773 3161.5831861262554 +r_3082 PI 4,5-P2 phospholipase C (1-16:0, 2-16:1), cytoplasm -1.7116301980490776e-11 1.6281768839180475e-09 -9512.433735825936 -8.367577733747878e-11 1.7360812626134239e-09 -2074.7715980115845 2.774089569192169e-11 1.7021161013880251e-09 6135.764757890247 -3.084897474520289e-11 1.5916017486823039e-09 -5159.334343614784 1.480327674171791e-11 1.554665808408969e-09 10502.173508839987 -1.4083403846781366e-10 1.7890056877926704e-09 -1270.293536460315 -3.853154032578098e-11 1.682349454775668e-09 -4366.161956027563 2.792435647775692e-11 1.4579881977487087e-09 5221.206078321146 -7.940914974221784e-11 1.964727148413267e-09 -2474.182326333008 +r_3083 PI 4,5-P2 phospholipase C (1-16:1, 2-16:1), cytoplasm -7.723597660254396e-11 1.6260349069557011e-09 -2105.281733308392 5.4466002780926604e-11 1.5863923367422664e-09 2912.628531091332 4.9976356178137586e-11 1.616195175603347e-09 3233.9195955834016 5.384620005009957e-11 1.539291948651934e-09 2858.682594537305 -1.2164767959188092e-11 1.587460563760194e-09 -13049.657577407215 9.606462530258376e-13 1.7165517710024327e-09 178687.18746319454 7.981200342525885e-11 1.769022278863789e-09 2216.4864969470627 -3.538082601362438e-11 1.7407978285390484e-09 -4920.17294301921 1.4786893246602675e-11 1.6040429346910004e-09 10847.734598067336 +r_3084 PI 4,5-P2 phospholipase C (1-18:0, 2-16:1), cytoplasm -2.5845668862761334e-11 1.68157743878001e-09 -6506.225270118049 -7.35523349770497e-11 1.945615949917029e-09 -2645.2130316788907 -2.433999263009422e-11 1.5337730137944687e-09 -6301.452252282508 -9.124986885114048e-11 1.829607738085218e-09 -2005.052457740985 -9.927022399129383e-11 1.694114802245085e-09 -1706.5689328893443 -1.1666260952993234e-10 2.015978126277406e-09 -1728.0413445236395 -1.707869033707509e-10 1.756297562897277e-09 -1028.3561141012303 -6.353532023324373e-11 1.625485946455203e-09 -2558.397345740765 -1.1335624055380079e-10 2.033303669393147e-09 -1793.7289199601732 +r_3085 PI 4,5-P2 phospholipase C (1-18:1, 2-16:1), cytoplasm -5.326171372458287e-11 1.700377713569219e-09 -3192.495311664019 3.586571149066883e-12 1.7611028864184762e-09 49102.68926009351 4.406151588005515e-11 2.012212853600602e-09 4566.8262051588845 -4.177826844470615e-12 1.8813651108231816e-09 -45032.14663655059 -8.259682178790706e-11 1.776171097670653e-09 -2150.410947084045 6.316292025705378e-11 1.901538512061377e-09 3010.5297606929767 3.986167337144138e-11 1.7034354657306412e-09 4273.366674443367 7.270778572377097e-11 1.517059998574065e-09 2086.516572430949 8.661088662819762e-11 1.7173580265831194e-09 1982.843142981988 +r_3086 PI 4,5-P2 phospholipase C (1-16:0, 2-18:1), cytoplasm 3.3117619358966956e-11 1.629370612829646e-09 4919.950903380609 6.033671344505609e-11 1.6234890259807602e-09 2690.715044430028 -1.5066887134354218e-10 1.898014240472721e-09 -1259.7255315897555 6.278383375727248e-11 1.6557676699524807e-09 2637.251615366172 2.8594878846276135e-11 1.6591013402506675e-09 5802.092567588302 -3.5756505240097444e-11 1.6755707842662264e-09 -4686.05858714413 5.3601997455823586e-11 1.5421041870296421e-09 2876.9528379993235 1.1446555449489347e-11 1.784001578949193e-09 15585.488462634234 3.4047423892199077e-11 1.9825419770088423e-09 5822.88393766872 +r_3087 PI 4,5-P2 phospholipase C (1-16:1, 2-18:1), cytoplasm -1.1437212326759667e-10 1.711686483602517e-09 -1496.5941303701086 5.749187649279232e-12 1.6877116700916332e-09 29355.654625453382 1.355670971794102e-11 2.117931089225932e-09 15622.751635841629 -5.845797856703966e-11 1.7065086140437015e-09 -2919.2056514350325 -4.383469743816668e-12 1.6335616826862138e-09 -37266.407165020806 4.121888214664415e-11 1.7365449978016474e-09 4212.9842134572045 2.984526161120041e-11 1.652127820807701e-09 5535.645297167327 -1.9339133433229915e-11 1.999710490958588e-09 -10340.228003818098 3.013669817031976e-11 1.58262134032306e-09 5251.47556437258 +r_3088 PI 4,5-P2 phospholipase C (1-18:0, 2-18:1), cytoplasm 1.2988274358456922e-10 1.53827482736251e-09 1184.3565857237293 7.26640072636899e-13 1.909207264348919e-09 262744.5603736951 1.744400325848284e-11 1.7294286750876663e-09 9914.1730797755 -9.557283053241756e-11 1.915231342216362e-09 -2003.9495864535804 6.35337363803743e-11 1.585731437853813e-09 2495.88884299216 7.175160203852156e-11 1.6074269549710279e-09 2240.266292741509 5.6304280524433236e-11 1.7584645272913155e-09 3123.145364637472 9.965698405449449e-12 1.9077217833769803e-09 19142.880967918903 3.496000402371472e-11 1.989387466662997e-09 5690.466927044742 +r_3089 PI 4,5-P2 phospholipase C (1-18:1, 2-18:1), cytoplasm 1.2483142149443432e-10 1.651420804974583e-09 1322.9207720335162 3.236299721767577e-11 1.7367503039624591e-09 5366.469280582871 2.222938324761957e-11 1.685902756263867e-09 7584.118450269653 1.6367744573290484e-10 1.650426813391372e-09 1008.341012410838 9.148339151384914e-11 1.629747048739574e-09 1781.467676012926 1.1615910254260152e-10 1.8270197791047902e-09 1572.8597579640627 -5.0106772691627003e-11 1.7896016188774852e-09 -3571.5763014538225 -3.789116381821614e-12 1.995810148563658e-09 -52672.17861500928 -7.776515665005544e-12 1.689495700678624e-09 -21725.61303105688 +r_3090 PI 4,5-P2 phospholipase C (1-16:0, 2-16:1), nucleus -7.658642346243793e-12 1.689905984575808e-09 -22065.346678639824 -2.2496620713168025e-11 1.5825277413920604e-09 -7034.51314563771 2.3582080612934166e-10 1.66122778968149e-09 704.4449626596343 6.273497717195919e-11 1.3510729774887731e-09 2153.619939615863 6.112173154142851e-11 1.3866321404731134e-09 2268.640147298919 -5.7650312341732204e-11 1.425822434887504e-09 -2473.2258629158755 -6.931712071806576e-12 1.354652684362118e-09 -19542.82968376472 -9.09451936424888e-12 1.4916837173752552e-09 -16402.00716091888 -7.894692047339689e-11 1.576543256926684e-09 -1996.9661229001824 +r_3091 PI 4,5-P2 phospholipase C (1-16:1, 2-16:1), nucleus -3.961914655780759e-11 1.979991238224436e-09 -4997.561558615269 2.429578385227077e-12 1.5273045116418163e-09 62862.94448981401 1.1550225947763679e-10 1.2271783476249415e-09 1062.4712911893678 1.3831523597320132e-10 1.849609379346271e-09 1337.2419649449423 -4.400728476763717e-11 1.59286741199491e-09 -3619.553945228405 1.2658503781012515e-11 1.3760106443125368e-09 10870.247132812989 5.924200035137257e-11 1.29359177873697e-09 2183.572079039359 1.6384122432520322e-10 1.19878484478226e-09 731.6747355371504 1.3141532363454536e-10 1.248277351387193e-09 949.8719912287736 +r_3092 PI 4,5-P2 phospholipase C (1-18:0, 2-16:1), nucleus 9.052093135344514e-11 1.3649707429955604e-09 1507.906207533305 -7.912186766164469e-11 1.5934926955692255e-09 -2013.9725497679208 -3.2250230886334795e-11 1.7169486981217774e-09 -5323.833817417073 -1.6394624243143374e-11 1.473197564056456e-09 -8985.857450637106 -9.685943399660148e-11 1.504681796922292e-09 -1553.469532947185 -4.7423807224034175e-11 1.553815852842027e-09 -3276.4468814190022 -1.2031962810064562e-10 1.4558946579907627e-09 -1210.0225715233494 3.5433690503846844e-11 1.3255911598934715e-09 3741.0474072678353 2.7336343383853304e-11 1.140788895749386e-09 4173.158347225083 +r_3093 PI 4,5-P2 phospholipase C (1-18:1, 2-16:1), nucleus -2.116110371633466e-10 1.940320737594813e-09 -916.927946483738 5.2543625303233393e-11 1.463092682666567e-09 2784.529377679869 6.956048993063602e-11 1.6957207488731644e-09 2437.7642402520382 1.6323657945708315e-10 1.340260943286416e-09 821.0542929434433 2.7515425470683502e-11 1.4379414538088155e-09 5225.946643423268 -1.6519683353736867e-10 1.680147255388934e-09 -1017.0577845905706 4.1308025002301405e-11 1.4582797229175531e-09 3530.2576747164926 9.461815997247624e-11 1.432284812178946e-09 1513.75255299362 1.3730819415297149e-10 1.1773733730018492e-09 857.4676699120868 +r_3094 PI 4,5-P2 phospholipase C (1-16:0, 2-18:1), nucleus 4.997006103201125e-12 1.476264968250041e-09 29542.989097098216 5.783981086828326e-11 1.3466642001956184e-09 2328.265220753113 1.2542781612801716e-11 1.860948595162593e-09 14836.80935067248 2.0485938917751328e-10 1.3079642883224231e-09 638.4692903624031 8.737329683706604e-11 1.4156555777414539e-09 1620.2382524049335 7.355441016503548e-11 1.324870675942721e-09 1801.2117464745932 3.817599267793841e-11 1.383158520762357e-09 3623.110818442904 1.061474123417426e-10 1.2768554116665728e-09 1202.9077143734078 7.895587831983818e-11 1.322349938133257e-09 1674.7960585994874 +r_3095 PI 4,5-P2 phospholipase C (1-16:1, 2-18:1), nucleus -2.4112170529606074e-11 1.931155284836465e-09 -8009.047889178209 4.394102454337185e-11 1.331537568355788e-09 3030.283390505604 8.948512001673922e-11 1.604317273527573e-09 1792.831336905473 1.1027716525177283e-10 1.3665928286464012e-09 1239.2346371312185 7.5592470828398e-11 1.37094302800167e-09 1813.597323884067 9.655795365853495e-11 1.3807112384470276e-09 1429.9300949663236 7.642937687605563e-11 1.2699362680610568e-09 1661.5813447236303 1.0694960843199627e-10 1.2947001062824342e-09 1210.570216445128 3.486919408820887e-11 1.8178414269205281e-09 5213.316437202194 +r_3096 PI 4,5-P2 phospholipase C (1-18:0, 2-18:1), nucleus 9.763577049680364e-11 1.4752110413818275e-09 1510.932964297263 3.803204846713575e-11 1.5852458708665295e-09 4168.184293928769 1.7153742166453063e-10 1.1181152179080764e-09 651.819997676503 1.673128733210921e-10 1.351076222918881e-09 807.5148051076828 5.807916339737232e-11 1.4232299946055431e-09 2450.5001645218854 3.024089343985767e-11 1.3910357873647503e-09 4599.850166898037 1.0015203923021671e-10 1.328853671714963e-09 1326.8363599270947 1.628187824081935e-10 1.2192504334751824e-09 748.8389333476715 -1.6685144263287818e-10 2.320849307305233e-09 -1390.9674802223788 +r_3097 PI 4,5-P2 phospholipase C (1-18:1, 2-18:1), nucleus -3.753668229185506e-11 1.886649156049667e-09 -5026.1478661875335 -2.4253780047733387e-10 1.960310677245122e-09 -808.2495484774221 -8.14030251829815e-10 2.4505517710865487e-09 -301.0393981769208 -9.7659349108223e-10 3.007993175882321e-09 -308.0087265940056 -3.5498396047103987e-10 2.1431226267822284e-09 -603.7237918970898 -1.4115463443545e-10 1.975454847147409e-09 -1399.4969807745026 -3.7971251354840386e-10 2.243757893318236e-09 -590.9096522393678 -8.69114076996633e-10 2.5859245408558793e-09 -297.5356871208401 -2.6989072880960415e-10 2.0757457428553903e-09 -769.1059830068247 +r_3098 PG phospholipase C (1-16:0, 2-16:1), mitochondrial membrane 5.23647280145406e-05 0.0010249705167334 1957.3681666958737 8.050700869081267e-05 0.0017133984568193 2128.259992120244 9.339847209852287e-05 0.0017015816043741 1821.8516493280435 0.0001187693149457 0.0023266365953631 1958.954294235471 6.252582546322086e-05 0.0023078766741384 3691.07749804282 0.0001652162613726 0.0035112956029381 2125.272399801791 0.0005185803001676 0.00839943469547 1619.6979894443143 0.0003373426804999 0.0081260895486032 2408.853079770356 0.0005200853197783 0.0101876810683671 1958.8480353009024 +r_3099 PG phospholipase C (1-16:1, 2-16:1), mitochondrial membrane 5.25487499708277e-05 0.00102184990523 1944.5750960723155 0.0001179097453193 0.0020637887234868 1750.3122561222729 6.354149773458107e-05 0.001387068738745 2182.9336546943955 9.536221717437963e-05 0.0020579160258769 2157.999349064912 0.0002225682198012 0.0044819040484927 2013.721479416727 0.0001839336515726 0.0036766540251804 1998.902318169592 0.000309989367794 0.0064592361610201 2083.6960335076656 0.0004614120523964 0.009722396779973 2107.0964075338325 0.0002449088121233 0.0069562842330504 2840.3568547578548 +r_3100 PG phospholipase C (1-18:0, 2-16:1), mitochondrial membrane 4.670132226070491e-05 0.0009564669077663 2048.0510218254853 9.522032212692535e-05 0.0018651634887598 1958.7872074972088 5.4741768901168873e-05 0.00128851037628 2353.7974788617826 0.0001190409531269 0.0023297342217451 1957.0863308363007 0.0001616918488559 0.0038026362188158 2351.779787121056 0.0001489903348865 0.0033283906653904 2233.9641480265363 0.0002155810816773 0.0053850641863329 2497.9298482195063 0.0002495777220393 0.007201132867126 2885.3267864949275 0.0003609335423927 0.0085000819751656 2355.026889110021 +r_3101 PG phospholipase C (1-18:1, 2-16:1), mitochondrial membrane 5.237835487088647e-05 0.0010252506173743 1957.393698029736 0.0001221955870431 0.0020980356979703 1716.948826661906 9.20232618913977e-05 0.0016784099874721 1823.8975156661493 0.0001555939160788 0.0026642117053642 1712.2852695691 0.0003639090882641 0.0057443052184504 1578.5000715018152 0.0001635807771516 0.0034804323974032 2127.653663227436 0.0002952238213479 0.0062996612101879 2133.85938215464 0.0004993969757722 0.0101828163565832 2039.0224311706515 0.0002247537218606 0.0065404469905259 2910.050581756645 +r_3102 PG phospholipase C (1-16:0, 2-18:1), mitochondrial membrane 6.640901691635446e-05 0.0011415225303071 1718.9270121932211 9.76441842143122e-05 0.0018713130914554 1916.4613914416504 6.19656817607976e-05 0.0013842670177353 2233.925260564289 0.0001093441277589 0.0022295533251603 2039.0242904275483 0.0002375208429144 0.00465254181546 1958.793071955724 7.8480559478869e-05 0.0023693207503961 3018.9906470201418 0.0003581888762214 0.0069429670355305 1938.3536163300928 0.0004589733240466 0.0097754875871506 2129.85963998136 0.0005210817467002 0.0101967051436503 1956.8340684012176 +r_3103 PG phospholipase C (1-16:1, 2-18:1), mitochondrial membrane 3.588794500481454e-05 0.000844575643137 2353.3686395913605 0.0001023603853669 0.0019319143405588 1887.3652474382584 9.276826185993553e-05 0.0016888250176459 1820.4771586599504 6.913787730294975e-05 0.00173575469225 2510.569835177769 0.0002908294260155 0.0051338559854531 1765.2464043231755 0.0002385398888039 0.004210506827317 1765.1164542875665 0.0005188520638792 0.0084035868378119 1619.6498815060495 0.0006254140768491 0.0114023760878194 1823.172280557773 0.0004009615653765 0.0089576193516961 2234.034412571212 +r_3104 PC phospholipase D (1-16:0, 2-16:1), cell envelope 4.958911392389635e-05 0.0009515026296174 1918.7732030818183 7.686773721012896e-05 0.0015917919631254 2070.819333180193 8.154223999854659e-05 0.0015459735106891 1895.9173928956773 0.0001117659933296 0.0019948606611561 1784.8547681871614 0.0002035593209292 0.0041263965959543 2027.1224020193688 0.0002003177054881 0.0034675593937336 1731.029908356373 0.0005820829140819 0.0091157805772615 1566.0622149747037 0.0007690408429377 0.0133002137637456 1729.4547989075372 0.00075490577609 0.0126890601287885 1680.8799893557484 +r_3105 PC phospholipase D (1-16:1, 2-16:1), cell envelope 5.8307785711446855e-05 0.0010722077477958 1838.875777416668 0.0001316658685767 0.0023812160366757 1808.5294711654583 0.0001425604066898 0.0020646372527892 1448.2543230124627 0.0001767354078645 0.002938020859024 1662.383839505234 0.0002182565793828 0.0042120136933304 1929.8450040961293 0.0002541867396589 0.0042630084976308 1677.1167934847829 0.0005495949329558 0.0087803751635653 1597.608463444648 0.0007391479903981 0.0120080090445137 1624.5744019469594 0.0005940966020744 0.010319907948368 1737.075740263985 +r_3106 PC phospholipase D (1-18:0, 2-16:1), cell envelope 6.75285038241981e-05 0.0011574738309962 1714.0522378662674 0.00014297927948 0.0023412074699477 1637.4452847022842 6.996940096345595e-05 0.0013574274496171 1940.0301144868968 0.0001158447431695 0.0020018611252044 1728.0552146202926 0.0003874000818709 0.0062986016047729 1625.8648099281888 0.0002963942409545 0.0044638609676987 1506.055230129439 0.0002915957183264 0.0047278528273405 1621.372513449359 0.0008283958219032 0.0129845921186431 1567.4381467558742 0.0007531248571685 0.0130013504721074 1726.3207220363945 +r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 7.837003123648772e-05 0.001280388132199 1633.7726449736244 0.0001004170507216 0.0019557227773816 1947.600296291018 8.537064666309933e-05 0.0015969823264486 1870.645694826348 0.0001200136642006 0.0021839787262291 1819.7750570947924 0.0003792529897565 0.0059382012109557 1565.7625309078694 0.0002532911570299 0.0046769527007114 1846.4729505575424 0.0004325416217914 0.0082001800202563 1895.812936173193 0.0008405977080759 0.0142310681312933 1692.970132391425 0.0008419607696989 0.0128616068906962 1527.577929230029 +r_3108 PC phospholipase D (1-16:0, 2-18:1), cell envelope 5.985038156993698e-05 0.001086785162424 1815.8366478485225 8.93857079592135e-05 0.0017833825415273 1995.154015383672 0.0001035254938224 0.0018598747833222 1796.5379489157033 0.0001393855116657 0.0023304542805672 1671.9487217264273 0.0003159664552066 0.0054654856431885 1729.767686767294 0.0003060236769275 0.004935868723471 1612.9041952004322 0.0003393065033961 0.0064877724846873 1912.06841594542 0.0004966802499726 0.0102778078679933 2069.3006956810227 0.000841955032064 0.0129317133331894 1535.9149646611486 +r_3109 PC phospholipase D (1-16:1, 2-18:1), cell envelope 5.7317987539936185e-05 0.0010736428074712 1873.134165297021 0.0001077752875029 0.0021529906094248 1997.6663104389245 0.0001023184949685 0.0017213331660653 1682.3284652440368 7.84708838340727e-05 0.001859137687758 2369.207019114513 0.0002648944207159 0.0048821693432602 1843.0623529421337 0.0002542071675276 0.0043917760498915 1727.6365936513698 0.0004865102325063 0.0083745867844909 1721.3588173363114 0.000686216347389 0.0124600028883318 1815.754307769041 0.0004967497272697 0.0099118476050088 1995.3403214708155 +r_3110 PC phospholipase D (1-18:0, 2-18:1), cell envelope 4.516675687038411e-05 0.0010013567969546 2217.0216910377244 9.148670656734489e-05 0.0019090088707885 2086.651648546649 0.0001323156037632 0.0020106615841074 1519.5952154706747 0.0001945340819723 0.0029419787771924 1512.320487682041 0.0001917835217933 0.0036053736696797 1879.9183767018988 0.000278066274019 0.0045600494697896 1639.9146159944382 0.0006806180996023 0.0095662072864648 1405.5176158339823 0.0006098582234986 0.010789667557775 1769.2091607581667 0.0006759204345121 0.0120207766649727 1778.4307221972765 +r_3111 PC phospholipase D (1-18:1, 2-18:1), cell envelope 6.535717956932011e-05 0.0011506153082812 1760.503307920217 0.000163398803473 0.0026028885432392 1592.9667096178655 0.0001241343038684 0.0019338253680349 1557.8492872404245 0.0001715579245438 0.0027856938919172 1623.762877362538 0.0005519523557442 0.0073634927902563 1334.0812324875565 0.0003255835832311 0.0050129245912774 1539.6736351163495 0.0003916111549072 0.0070705668528444 1805.5070097578564 0.0009861333456994 0.0144034602333904 1460.599653809901 0.0008052217560417 0.0127273350349064 1580.599994897195 +r_3112 PI 3-P phosphatase (1-16:0, 2-16:1), cell envelope 5.905732071164387e-05 0.0014753952375893 2498.2427577323288 5.356341297333434e-05 0.0018931620751013 3534.431377708914 3.4062554213642935e-05 0.0013903062448208 4081.62651602915 0.0001006341815725 0.0029036016400976 2885.3035765035647 0.0001673869517192 0.0052911181692397 3161.009932311191 0.0002458835519001 0.0057908593627181 2355.122706650536 0.0002013391801085 0.0071162657477652 3534.466438141316 0.0007639561396358 0.0170671912397009 2234.053809402796 0.0005131931460103 0.0137074643351699 2671.0146933439137 +r_3113 PI 3-P phosphatase (1-16:1, 2-16:1), cell envelope 2.948617556339445e-05 0.0010417037580268 3532.854763708416 4.031470685747305e-05 0.0016455048759722 4081.649115767299 8.994971957649647e-05 0.0022478127923255 2498.965869942392 0.0001005804495017 0.0029020508621641 2885.303134496119 0.0001339478537435 0.0047343419399346 3534.4664416935 0.0001352382376297 0.0042759697716849 3161.805304939327 0.0004023097941799 0.0100507229765301 2498.254609241153 0.0002289559936671 0.0093452260002744 4081.669079981396 0.0002935552037274 0.0103756261915327 3534.4719016350373 +r_3114 PI 3-P phosphatase (1-18:0, 2-16:1), cell envelope 4.4251987998524655e-05 0.0012767989879703 2885.291815619536 0.0001343038653101 0.0030004175614225 2234.051532689248 6.810902387360231e-05 0.0019651441581229 2885.2919134032927 0.0001004162413679 0.0028973238218385 2885.313951575973 0.0003335677443789 0.0074525908904759 2234.206099379395 8.208148401307775e-05 0.0033502808806776 4081.6524225413687 0.0001989770438984 0.0070341552680658 3535.1591973880177 0.0001527913368597 0.0076387954080403 4999.495105571801 0.0002935553093106 0.0103756265280846 3534.470745036319 +r_3115 PI 3-P phosphatase (1-18:1, 2-16:1), cell envelope 4.414729668464112e-05 0.0012738015040871 2885.344290017047 0.0001209425414442 0.0028483195036316 2355.101413959823 3.330071008187556e-05 0.0013599212593306 4083.7605444059454 3.343585052496705e-05 0.0016716233724643 4999.494094567976 0.0001339480807898 0.0047343432094446 3534.461398421876 5.998953791524324e-05 0.002760911211686 4602.321184048518 0.0004530127563069 0.0106690596500511 2355.1344860631098 0.0003055824865383 0.0108007257268898 3534.4714447613483 0.000730822833651 0.0163282670121257 2234.230549496357 +r_3116 PI 3-P phosphatase (1-16:0, 2-18:1), cell envelope 2.95291998391804e-05 0.0010436855590699 3534.418693205447 4.0313228650858506e-05 0.0016454435563736 4081.64667391048 4.541649348806579e-05 0.0016052262465508 3534.456588932028 0.0001504730973694 0.0035439055964065 2355.175548560152 0.0001004609234293 0.0041004711715686 4081.657854211209 0.0001094416813165 0.0038681845802974 3534.4710842915383 0.0003523294271479 0.0094107424612263 2671.0066591387763 0.0002291869802386 0.0093546390796554 4081.662522851992 0.0004403158629684 0.0127044575275563 2885.305435490691 +r_3117 PI 3-P phosphatase (1-16:1, 2-18:1), cell envelope 4.429121656661497e-05 0.001277895280834 2885.21151572356 6.717430214084413e-05 0.0021233695827644 3160.9849527165966 3.479390738399621e-05 0.0013912493476819 3998.5429987142816 8.383798857217534e-05 0.0026500620513793 3160.9322891828347 0.000100460929485 0.0041004718732399 4081.6583066254702 0.0003256525559839 0.0066425000735442 2039.750633455076 5.0334833419049806e-05 0.003559200926481 7071.049380157579 0.0009923097331883 0.0194375033962895 1958.814143023256 7.317676248074837e-05 0.0051743599946431 7071.042526655178 +r_3118 PI 3-P phosphatase (1-18:0, 2-18:1), cell envelope 3.69111948913278e-05 0.001166758141121 3160.9871871016926 5.375296393347526e-05 0.0018998743714372 3534.455093096929 6.81246162023893e-05 0.001965599191807 2885.2994723192 0.000100636693751 0.0029036714921045 2885.30096118574 0.0002339221270413 0.0062481492623367 2671.038153321977 0.0002461890122558 0.0057980823121392 2355.134479402764 5.0334884796617066e-05 0.0035592017595628 7071.043817710319 0.0003819232362118 0.0120726380441289 3161.011663985996 0.0005137216273991 0.013721543279657 2671.0075160990827 +r_3119 PI 3-P phosphatase (1-18:1, 2-18:1), cell envelope 1.4748049057639973e-05 0.000737321336463 4999.449985427428 6.719167148847968e-05 0.0021239122716475 3160.9754968094235 0.0001471295100841 0.0028820723757577 1958.8676493995897 5.022506507427297e-05 0.0020500144946173 4081.6562240103567 6.697167016169206e-05 0.0033482385933168 4999.484984073204 8.186705550213551e-05 0.0033415598660842 4081.6905476674046 0.0003020084369611 0.0087138655477314 2885.305336305348 0.000305366617972 0.0107930994802899 3534.472612614448 0.0005132256629854 0.0137083278095955 2671.0137076647443 +r_3120 PI 3-P phosphatase (1-16:0, 2-16:1), cytoplasm 5.750242546930308e-05 0.0014402273357499 2504.637541800457 0.0001921346421776 0.0035361774732611 1840.468451281092 5.671269912711823e-05 0.0017927014468475 3161.0229709386986 1.6772923060371226e-05 0.0011860117538536 7070.990247703689 0.0001155082263917 0.0042078870393812 3642.932777020846 0.0001097692701286 0.0038682447718546 3523.977855842977 0.0004026776819628 0.0100598926474252 2498.24936867356 0.0005118716245688 0.0137393695149419 2684.143612475971 0.0001823829719332 0.0077442770636314 4246.162337163949 +r_3121 PI 3-P phosphatase (1-16:1, 2-16:1), cytoplasm 2.230183596494132e-05 0.00090396088771 4053.302558278719 5.4204460127590304e-05 0.0018979680993061 3501.4980221896044 4.644591275380314e-05 0.0016054330467441 3456.564747158852 0.000101730065821 0.0029038384506279 2854.4545087926003 0.0001689755311662 0.005292802065034 3132.289053037577 0.0001390234096497 0.0043244711372698 3110.606442587125 0.0005546075495087 0.0114969220013201 2072.983321540424 0.0003456886559564 0.0111156306278022 3215.5034411083548 0.0003685773734061 0.011599281598338 3147.041146651469 +r_3122 PI 3-P phosphatase (1-18:0, 2-16:1), cytoplasm 5.311945679915998e-05 0.0013502895073286 2541.986663067697 5.354082764931032e-05 0.0018924174332136 3534.531527246538 4.526908964208765e-05 0.0016000528390511 3534.537256440835 0.0001755618889558 0.0037837150129537 2155.2029517666474 0.0002381190790113 0.0060908048863252 2557.881926813532 5.472073428677427e-05 0.0027357662750102 4999.505782712996 0.0001509492731727 0.0061612484981822 4081.6682112339295 0.0001527911142967 0.0076387949642438 4999.502097620139 0.0002201662975559 0.008986456511 4081.667635218695 +r_3123 PI 3-P phosphatase (1-18:1, 2-16:1), cytoplasm 8.846982111099801e-05 0.001766532790886 1996.7631546013065 6.719111002540985e-05 0.0021239114472294 3161.000683611587 4.479311278820728e-05 0.0015834384201064 3535.004203868032 0.0001507317356098 0.0035499693798652 2355.157237128577 0.0001672459280148 0.0052866812199842 3161.0223834663843 5.333310834563557e-05 0.0026672924764587 5001.19449099577 0.0001252155334184 0.0053182792401361 4247.299911555325 0.0004172670248125 0.0122895641685235 2945.251706397186 0.0007102717219923 0.0159467588043586 2245.1631270954013 +r_3124 PI 3-P phosphatase (1-16:0, 2-18:1), cytoplasm 5.140802101648313e-05 0.0013731850725271 2671.149453675463 8.050260956768296e-05 0.0022253355899297 2764.3024268161016 3.944503438119047e-05 0.0014383636303131 3646.50114489203 6.687858459725649e-05 0.00236383966529 3534.524062560763 0.0002337918691232 0.0060245308329323 2576.8778253605587 0.0001368021791713 0.004324328819846 3161.008725181541 0.0002013387602217 0.0071162663998015 3534.474133029702 0.0005330626911305 0.0142385866218231 2671.090447471742 0.0004397411751216 0.0126879341765542 2885.318658878149 +r_3125 PI 3-P phosphatase (1-16:1, 2-18:1), cytoplasm 7.382137799207652e-06 0.00052199889401 7071.107424546424 2.685392958987573e-05 0.0013425607781858 4999.494668713386 5.094618726710064e-05 0.001652014047984 3242.6647343065733 4.171310504793124e-05 0.0017736114494286 4251.928614258407 0.0001838697284311 0.0054182090766518 2946.765148827007 0.0002512137737827 0.0055986949242678 2228.657624923745 0.0003013981440071 0.0086963530343974 2885.337288006818 0.0006111649795138 0.0152684233305799 2498.249055880848 0.0003668764383715 0.0115970125752217 3161.013181085494 +r_3126 PI 3-P phosphatase (1-18:0, 2-18:1), cytoplasm 2.214646145125247e-05 0.0009039473750761 4081.6785880933735 7.378323160114668e-05 0.0021732753899198 2945.486857593943 7.947848324744549e-05 0.002122876786195 2671.0081766228304 5.848588922108743e-05 0.0021332883350756 3647.526546123596 0.0001674344552356 0.0052926267814935 3161.014125823217 0.0002285709046223 0.0054629989708857 2390.0675284603017 0.0001002604923875 0.0050125675402463 4999.544108431062 0.0004194020024292 0.0123552003431255 2945.908763325593 0.0003669440934522 0.0115991470074394 3161.012049087515 +r_3127 PI 3-P phosphatase (1-18:1, 2-18:1), cytoplasm 1.1772406504549169e-05 0.0006072819211397 5158.51980565785 0.0001006601588002 0.0025543385191689 2537.5864191087016 9.52618226367368e-05 0.0022181333927018 2328.459955212401 4.171307161119322e-05 0.0017736106749124 4251.930165786427 0.0001674344070875 0.0052926252066647 3161.014094252549 0.0001771118668825 0.0048185220124812 2720.609351193958 0.0003766855078913 0.0095607653463711 2538.129327005688 0.0003051021665898 0.010783797182753 3534.4872516916366 0.0004402071267302 0.0127013327312316 2885.308292388286 +r_3128 PI 3-P phosphatase (1-16:0, 2-16:1), ER membrane 3.5639815920322566e-05 0.0015019039295826 4214.118088994428 0.000241872853617 0.0056964284916983 2355.1334540072926 0.0002270209704547 0.0050717662925915 2234.0518950443206 0.0002012727780991 0.0058073415164291 2885.3089678959795 0.0007361930975097 0.0156800243848004 2129.879299037248 0.0001641623866406 0.0067005642779062 4081.668410788682 0.0007046859432498 0.0188222151318666 2671.0076044744533 0.0004582480150979 0.0187041594605975 4081.667316463461 0.0016142000470112 0.0343804275694785 2129.8740285093872 +r_3129 PI 3-P phosphatase (1-16:1, 2-16:1), ER membrane 0.0001476355179744 0.0032982592090348 2234.055364377822 0.0002150112419398 0.0053715056553707 2498.2440950099 0.0001135405899988 0.0035890337858576 3161.013859354722 0.0003023560233023 0.0071104111631742 2351.6684356122605 0.0004018428862428 0.0115944048016763 2885.307964533561 0.0003283248376815 0.0094731791874616 2885.3068973871923 0.0014079259328569 0.026572787089267 1887.371094539495 0.0007639559815246 0.0241487418213793 3161.0122055964234 0.0011737017139392 0.029322014976068 2498.251014532077 +r_3130 PI 3-P phosphatase (1-18:0, 2-16:1), ER membrane 8.858629430272985e-05 0.0025559832558957 2885.3032808450703 0.0003225161316044 0.0065760873933799 2038.9948746644827 9.083247500212928e-05 0.0032104525750756 3534.476601017831 0.0002348184527229 0.006272016944103 2671.0068443823448 0.0002009217521376 0.0082009409569695 4081.659088535073 0.0004920513338927 0.0115885167840082 2355.143861175476 0.0007045850067966 0.0188195265472893 2671.008659813788 0.0012221594856474 0.0305325891500961 2498.249165404169 0.0008806653888956 0.0254099064607899 2885.3077208649006 +r_3131 PI 3-P phosphatase (1-18:1, 2-16:1), ER membrane 0.0001327590350411 0.0031266627308222 2355.1411998832973 0.000134216342303 0.0042425931468608 3161.0108531200685 0.0001589568165679 0.0042457532110397 2671.0104685718607 0.0003326178434938 0.0074319664568971 2234.385978464508 0.0006022423155153 0.0141836537700627 2355.140680861205 0.0007108516166692 0.0139242482791483 1958.812212370287 0.0005033470736147 0.0159108652372733 3161.0127626270046 0.0019862855825059 0.0389074842526128 1958.8061553327304 0.0011739218320733 0.0293275011901612 2498.2499165522104 +r_3132 PI 3-P phosphatase (1-16:0, 2-18:1), ER membrane 8.857342105515794e-05 0.0025556061005813 2885.296819448702 0.0001880082735246 0.0050217252377576 2671.012899386866 0.0001589569590398 0.0042457533617579 2671.008169384209 0.0003352453952758 0.0074895794657216 2234.058862929174 0.0004685995833914 0.0125163431379087 2671.0102999499486 0.0003830367921897 0.0102309464619786 2671.008809229434 0.0005029770044549 0.0158991855414791 3161.016388554168 0.0009167471209616 0.0264509759825091 2885.307777652058 0.0011735866000503 0.0293191487309118 2498.2518315779143 +r_3133 PI 3-P phosphatase (1-16:1, 2-18:1), ER membrane 7.382191186981116e-05 0.0023335162835541 3161.0076526728285 0.0002148111051515 0.0053665274499142 2498.254196927531 0.0002273137775347 0.005061893114742 2226.8307577473706 0.0002012728878119 0.005807343858618 2885.308558817588 0.0007366223691331 0.0156891237039152 2129.8733735684364 0.0006018436098984 0.012818511597953 2129.8741711513785 0.0011067609870194 0.0235726351561169 2129.8758659355453 0.0012223134007382 0.0305364344753704 2498.24917708726 0.0016143464160986 0.0343835422280404 2129.873853911367 +r_3134 PI 3-P phosphatase (1-18:0, 2-18:1), ER membrane 8.858610493297463e-05 0.0025559838303888 2885.310097246941 0.0002148349740624 0.0053671036712225 2498.24484800227 0.0001360521882083 0.0039255441895307 2885.322346685594 6.696544591470373e-05 0.0033479387771886 4999.501954266109 0.0005983132584983 0.01409314745398 2355.479717991122 0.0003825254458793 0.0102173287044084 2671.019356874558 0.0007043412521652 0.0188130204839128 2671.0093191445944 0.0013749592565866 0.0323821621446074 2355.136124178414 0.0005871101445987 0.0207512521384338 3534.4734423924456 +r_3135 PI 3-P phosphatase (1-18:1, 2-18:1), ER membrane 0.0001032823976885 0.002758685711381 2671.012460128208 0.000349242116154 0.006840985100203 1958.808741493679 0.0001127205594999 0.0035634922559145 3161.350752446051 0.0002348183238276 0.0062720181789883 2671.0088364276708 0.000736503595086 0.0156866043477247 2129.8747830135035 0.0003280633787591 0.0094656555639976 2885.3130757233894 0.0006034976101006 0.0174127973104945 2885.313383028956 0.0013771457646683 0.0323762579474099 2350.9681239303964 0.0017530473387678 0.0357477675637835 2039.1786789345065 +r_3136 PI 3-P phosphatase (1-16:0, 2-16:1), Golgi membrane 0.0001328257665432 0.0031282315236902 2355.1390706038515 0.000159570048595 0.0046053516191239 2886.1002798915047 9.08326888011884e-05 0.0032104535023681 3534.469302560279 0.0002005839204439 0.0057875601669217 2885.355991703372 0.0002674974620746 0.0094546560246399 3534.48438400561 0.00043767669058 0.0109342583455474 2498.2500966767266 0.0006023275530266 0.0173793446404901 2885.3643757722025 0.0010689509806551 0.0285517953098899 2671.010722343095 0.0007332215187023 0.0231772631625783 3161.017860413604 +r_3137 PI 3-P phosphatase (1-16:1, 2-16:1), Golgi membrane 0.0001323607631721 0.0031174627471264 2355.277102075019 0.0001612261969318 0.0046518564369375 2885.2981249094623 9.083266559928324e-05 0.0032104524759052 3534.469075330742 0.0003327662290918 0.0074352287486647 2234.369986688595 0.0004014608048436 0.0115834072208619 2885.314601352565 0.0002176711469733 0.0076938892036521 3534.6389774818645 0.0006040165388838 0.0174277357932639 2885.30771449871 0.0007630692629988 0.0241207437873109 3161.016300475419 0.0005798440554541 0.0204990610355322 3535.27139628562 +r_3138 PI 3-P phosphatase (1-18:0, 2-16:1), Golgi membrane 8.858613811714703e-05 0.0025559844671019 2885.309735166325 0.0001854996454521 0.0049577029489048 2672.621253167346 0.000226448845098 0.0050590407872399 2234.076656496052 0.0002683638624444 0.0067043992993806 2498.249666818888 0.0007361999622407 0.015680148000357 2129.8762299080886 0.0003277421309266 0.0094564013501164 2885.31758897751 0.0004026776150976 0.0142325342154966 3534.4736538298785 0.0009137630934318 0.0263654257008133 2885.367760016617 0.0014629586783273 0.0326837981530891 2234.088948462892 +r_3139 PI 3-P phosphatase (1-18:1, 2-16:1), Golgi membrane 0.0001033281838876 0.002759903533894 2671.007492879224 0.0001340260779328 0.0042365723654084 3161.0060002891014 0.0001426801703465 0.003957192065676 2773.470241914856 0.0001341802762575 0.0047425695199144 3534.475894812052 0.000334341339418 0.0105685977039099 3161.0203279990947 0.0002735877108745 0.0086481456480631 3161.0139287396005 0.0010041140460821 0.022432832740181 2234.0921161006454 0.0006106059876314 0.0215817338747072 3534.4779304283747 0.0013207113704371 0.031104556490038 2355.136571569149 +r_3140 PI 3-P phosphatase (1-16:0, 2-18:1), Golgi membrane 7.350362829448806e-05 0.0023235171431234 3161.0917678980886 0.0002150053348291 0.0053713469801742 2498.238931812091 0.0002039804697214 0.0048040654218433 2355.159505419422 0.0002760888925794 0.0067254694987307 2435.979744022009 0.0003348689140648 0.0105852512098288 3161.013389191124 0.0003282878967138 0.0094721196959092 2885.3088373721994 0.0009058108629739 0.0213330831744419 2355.13660151973 0.0010655806114643 0.0284627555347586 2671.1029863470067 0.0005871101914483 0.0207512549663482 3534.47364201889 +r_3141 PI 3-P phosphatase (1-16:1, 2-18:1), Golgi membrane 0.0001248680448566 0.0029889055558076 2393.6512814290927 0.0001878195166742 0.0050167085402123 2671.026221899203 9.00810282877096e-05 0.0031842258395947 3534.8462380165784 0.0002011835365065 0.0058047600107772 2885.305682350626 0.0004018425317051 0.0115943875879261 2885.3062264781274 0.0004360118299498 0.0108932812431165 2498.3912120847594 0.0006037011792784 0.0174186492435121 2885.3097925586057 0.0009167470428362 0.0264509742317235 2885.307832560887 0.0007338877890432 0.0231982878464235 3161.012922243234 +r_3142 PI 3-P phosphatase (1-18:0, 2-18:1), Golgi membrane 0.0001180585776993 0.0029493972935972 2498.249048119554 0.0001343817030495 0.0042478254175523 3161.014722357869 9.083247395056204e-05 0.0032104527424635 3534.476826218522 0.0001548391383268 0.0049619111167659 3204.558724870228 0.0003346263033473 0.0105775926352838 3161.0164919711465 0.0001641620958981 0.0067005523003933 4081.6683435553314 0.0004026774546143 0.0142325300322157 3534.474023594488 0.0007632947075301 0.0241278783125956 3161.017373049543 0.0008804226892731 0.025402907644178 2885.3081541039187 +r_3143 PI 3-P phosphatase (1-18:1, 2-18:1), Golgi membrane 0.0001180968881601 0.0029503565063307 2498.250844958694 0.0001075053789872 0.0037997505508692 3534.474820388745 9.083264533354126e-05 0.0032104519526831 3534.46928788013 0.0002345029896932 0.006263630337846 2671.0236598859137 0.0005357122921453 0.0133834268349641 2498.248972665619 0.0003283247518015 0.0094731806046134 2885.30808372862 0.0004026776280376 0.01423253102162 3534.472747089897 0.0010688783592363 0.0285498621328061 2671.0113350225342 0.0011741793130764 0.0293339259539178 2498.249256074976 +r_3144 PI 4-P phosphatase (1-16:0, 2-16:1), cell envelope 8.858611998917572e-05 0.0020863249858873 2355.1375612141887 5.375267267076542e-05 0.0023271722488593 4329.407512652017 5.677012206313391e-05 0.0021236052390202 3740.709305959577 8.712087512802222e-05 0.0031311112161571 3593.985036945564 0.000368335852214 0.0091639201887444 2487.925118790583 0.000410404747612 0.0088571480462756 2158.1495091885404 0.0001006693641192 0.0071184089487847 7071.077691869439 0.0009207434176977 0.0228731760461535 2484.207392255394 0.0008803591091569 0.0219913515425596 2497.9978413148524 +r_3145 PI 4-P phosphatase (1-16:1, 2-16:1), cell envelope 2.9527920378929005e-05 0.0010436582805604 3534.479459329734 0.0001075056156857 0.0032902410165004 3060.5294388689235 5.6770479720617614e-05 0.0021236049694536 3740.6852644270566 0.0001060634905092 0.0033750977482564 3182.1484773415004 0.0001674273580121 0.0052924004722141 3161.0129521543017 0.0001641623120785 0.0061163807025069 3725.812962222561 0.0006543511694318 0.0155019454105207 2369.055964854681 0.0012864763108243 0.0288707065410396 2244.169309463566 0.0005136845119779 0.015560324639223 3029.159781225814 +r_3146 PI 4-P phosphatase (1-18:0, 2-16:1), cell envelope 8.10786701394182e-05 0.0018770707233448 2315.1227321774127 6.719157715273458e-05 0.0025134055144337 3740.6556311671247 7.947847446687618e-05 0.0024074920049758 3029.1119968328253 5.03181001513688e-05 0.0026517907798724 5270.053463654642 0.0003972940052655 0.0087710449421918 2207.6962717643887 0.0004375664191696 0.0102236453273288 2336.478504618621 0.0005033470884417 0.014229329635141 2826.9418780571914 0.0007636030588713 0.0215893234140655 2827.296612192129 0.0006498851537666 0.0169670202855576 2610.77210138094 +r_3147 PI 4-P phosphatase (1-18:1, 2-16:1), cell envelope 5.167544869315604e-05 0.0017306763028961 3349.1268032770995 0.0001209434649542 0.003424284702101 2831.310235238941 0.0001701823677516 0.0041659643003172 2447.9412029310347 8.386360029805574e-05 0.0031370853213052 3740.699552792777 0.000234355772755 0.0085341289492243 3641.527088877289 0.0001641623072684 0.00547016397611 3332.168064112756 0.0004530121631888 0.0137786598214697 3041.565092751261 0.0004583734279468 0.0152737689363672 3332.167181850476 0.0008072189862866 0.0200830899505542 2487.935776007944 +r_3148 PI 4-P phosphatase (1-16:0, 2-18:1), cell envelope 8.858611670446858e-05 0.0019513224450668 2202.7406975932954 0.0002284443029146 0.0051124115720038 2237.9247399810965 0.0001930190914411 0.0038458966925046 1992.495490362944 6.708352592349512e-05 0.0023710434060416 3534.4644954197584 0.0004009804521737 0.0110743191070163 2761.810219670415 0.0002188831646842 0.0066989973125801 3060.5356616825875 0.0007040464008962 0.0158931859323145 2257.406033477564 0.0003811783931123 0.0142459479725276 3737.344044138729 0.0008804772740286 0.0231896028174589 2633.7537039830727 +r_3149 PI 4-P phosphatase (1-16:1, 2-18:1), cell envelope 6.643953099769981e-05 0.0020208038506068 3041.5685063712963 0.0001612373221886 0.0042465640053043 2633.7351350544686 0.0001464504932827 0.0034786016148376 2375.274768191471 0.0001845000337839 0.0048870612535327 2648.81320252498 3.348672072993547e-05 0.0023678815692639 7071.106150884387 0.0001635536432008 0.0054398237106496 3326.0180599999176 0.0007042205153918 0.0166739426321031 2367.7161155727563 0.0005347690850614 0.0179101652640213 3349.139986647608 0.0006598399523223 0.0200654837545192 3040.962233932289 +r_3150 PI 4-P phosphatase (1-18:0, 2-18:1), cell envelope 5.905753009628576e-05 0.0018074742471703 3060.5313907024743 8.062964321302607e-05 0.0026866938727751 3332.141586781961 0.000113540580167 0.0027791279119564 2447.69571184816 0.0002009232455407 0.0050225398447803 2499.7305967571774 0.0002675916299361 0.0088451946363342 3305.482551320578 0.0003554120761183 0.00885534737188 2491.571887087608 0.0008050833909934 0.0174125752604817 2162.8287771524747 0.0008400397325467 0.0235283895524283 2800.866273443827 0.0002201659973198 0.0116028491106724 5270.0458980571575 +r_3151 PI 4-P phosphatase (1-18:1, 2-18:1), cell envelope 0.0001253264265777 0.0027057610839413 2158.9709032856026 0.0001203230772425 0.0034122438238636 2835.901393201681 9.074245014186552e-05 0.0027781319092627 3061.5570826216963 0.0002180458647472 0.0056843032728957 2606.93009678744 0.0003013821049404 0.0091667293279638 3041.563907643303 0.000437727810846 0.0102279550661787 2336.601607837098 0.0002013349207582 0.0087166633686249 4329.434424885831 0.0006856269020277 0.0208540422173716 3041.602095205961 0.0007326434090794 0.0219652747665331 2998.085356985732 +r_3152 PI 4-P phosphatase (1-16:0, 2-16:1), cytoplasm 0.0002794319343785 0.00415769077188 1487.908238236031 0.0003583719098282 0.0064467156825989 1798.889786224795 0.0003711780013739 0.0056674293584416 1526.876414405733 0.0006001369998314 0.0089276764760178 1487.6064096239636 0.0011234411152341 0.0165422309356709 1472.4608803572128 0.0010026792184645 0.0138265225942078 1378.9577304076504 0.0007128140535202 0.0161382299643111 2264.01680559074 0.0020992531154367 0.0342490777520276 1631.4887185436753 0.002266660680138 0.0361753205574078 1595.9742397439163 +r_3153 PI 4-P phosphatase (1-16:1, 2-16:1), cytoplasm 0.0001617066240775 0.0029355722776696 1815.369218432074 0.0004282765539236 0.0068133651061655 1590.8797817078043 0.000315066333953 0.005504286632745 1747.02468641599 0.0002330327669569 0.0051801171135729 2222.9136190666163 0.0008527708386585 0.0139426361405744 1634.9804083951285 0.0008263005342682 0.0127026442938236 1537.291066267066 0.0012396074728735 0.021188360144128 1709.2798008881864 0.0022193367783216 0.0342975734729772 1545.3974271950842 0.0024225065953505 0.0350724316956854 1447.7744565484072 +r_3154 PI 4-P phosphatase (1-18:0, 2-16:1), cytoplasm 0.0002127431089222 0.0033578611999634 1578.3642614677206 0.0004701337954987 0.0071561622589505 1522.1544010379753 0.000278166313469 0.0046342943847066 1666.0156749076737 0.0003670302722759 0.0068113829835577 1855.8095879449827 0.0010848894699017 0.0149153892213764 1374.8303062363273 0.00089533328851 0.0139871632389535 1562.2297772743882 0.0016525141332657 0.0262663467539533 1589.4778885820608 0.0027117862938661 0.0392477044688998 1447.3007905407076 0.0022476458132185 0.0334816346154382 1489.6312585609053 +r_3155 PI 4-P phosphatase (1-18:1, 2-16:1), cytoplasm 0.0001868501488967 0.0032514384685346 1740.1315908672889 0.0003471247937503 0.0056636100432241 1631.5775033047423 0.000309249763745 0.0048488539627 1567.941040270846 0.000421405801309 0.0075305803742682 1787.0139307230013 0.0011806987471067 0.0171640209972439 1453.717219511248 0.0009122747063091 0.0133727821392356 1465.8722911806035 0.0017546562359796 0.0255621215469639 1456.816499027324 0.0022632448307104 0.0337847148823406 1492.7556411003 0.0024627687729956 0.0347881900038534 1412.5641995021124 +r_3156 PI 4-P phosphatase (1-16:0, 2-18:1), cytoplasm 0.0003213603299034 0.004199446972857 1306.7720505885882 0.0003532390012144 0.0056628158654131 1603.1117305690132 0.0003698610690799 0.0052976179207268 1432.3264500115074 0.0006396709637684 0.0094400466071726 1475.7660018767997 0.0011566270091169 0.0173703542771933 1501.8112269793426 0.0005692977658984 0.0103407874879131 1816.411043102063 0.0013920540482776 0.0217097143823605 1559.5453645798248 0.0019743852780459 0.033982852613643 1721.18648733424 0.0027422728664393 0.0383917580879513 1399.9977375628653 +r_3157 PI 4-P phosphatase (1-16:1, 2-18:1), cytoplasm 0.000241818749428 0.0036850368141685 1523.8838274053587 0.0005018998295795 0.0072257140718768 1439.6725493869556 0.0003267760318588 0.0050753178497226 1553.1487486555543 0.0004703900795166 0.0071778076233824 1525.9266587333775 0.0008959097046637 0.015417114222155 1720.8334882299014 0.0008557878028417 0.0132166629287844 1544.3855223101832 0.0015757585283618 0.0232390189662995 1474.7830043768822 0.002582945721254 0.0379635052978788 1469.7755738919125 0.0021048054351449 0.0345150300706696 1639.820455342562 +r_3158 PI 4-P phosphatase (1-18:0, 2-18:1), cytoplasm 0.0002685721661646 0.0036745782262286 1368.190262864335 0.0003583525645696 0.0058744892610492 1639.3043728049197 0.0004743264401358 0.0061458311826131 1295.6965209134 0.0004679438105193 0.0076409296013074 1632.8733128934882 0.0006790569087374 0.0126987577279922 1870.057953110577 0.0007257987514201 0.0116007624829731 1598.3442325127664 0.0015853733717095 0.0242345983355643 1528.636645980196 0.0023471487558562 0.0373495031165506 1591.2712401956896 0.001737967311085 0.0316895536069759 1823.36879438728 +r_3159 PI 4-P phosphatase (1-18:1, 2-18:1), cytoplasm 0.000192926111199 0.0030195495001244 1565.132620648316 0.0004172794589619 0.0064491781011931 1545.5297313786457 0.0002916373137975 0.0051589744640384 1768.9692710652384 0.0005703200536216 0.0083078591775453 1456.7012197429017 0.0009365533361822 0.0155458136283726 1659.896241653796 0.000886458938791 0.0138475787168544 1562.122971622368 0.0013905670813252 0.0226963194999968 1632.1628639710057 0.0019257172898569 0.0334230085636231 1735.6134641189417 0.0022975317761598 0.0348742820433831 1517.902054946659 +r_3160 PI 4-P phosphatase (1-16:0, 2-16:1), ER membrane 9.705563666857968e-05 0.0026090172732473 2688.166666874217 6.891679068823875e-05 0.0028493095224994 4134.4199200873945 0.0001805558745287 0.0043900361025748 2431.400315294547 0.0001769065871704 0.0053148180651714 3004.307612384298 0.0003521201585691 0.0106022549742281 3010.976428418473 0.0003983845155071 0.0102497461312708 2572.827439897441 0.0009151843107186 0.0212920431630539 2326.53061396286 0.0012427204704778 0.0305471077121891 2458.083570510756 0.0006679005684598 0.0213910957062565 3202.736562357501 +r_3161 PI 4-P phosphatase (1-16:1, 2-16:1), ER membrane 0.0001117071327871 0.0028066833380117 2512.537264169539 0.0002174276437543 0.0053665140874679 2468.183895480421 0.0002198326818264 0.004883245964351 2221.34667319636 0.0002774964728699 0.0067133335937518 2419.25006264774 0.000188875200869 0.0071316270967703 3775.840906564067 0.0002444478210585 0.0077777394479799 3181.7585504746808 0.0005262191665226 0.0159302084142852 3027.295360515824 0.0007841106981421 0.0241621117666346 3081.4669183680203 0.0004200598402517 0.0156240518659505 3719.482409121811 +r_3162 PI 4-P phosphatase (1-18:0, 2-16:1), ER membrane 0.0001038940152462 0.0027607487252943 2657.2740679541903 0.0002418844969091 0.0056967092311018 2355.136151301448 0.0001011236198612 0.0032265953596608 3190.743531619373 0.0002043347627454 0.0058112736860633 2843.996590684429 0.0002798814659129 0.0094496163440294 3376.2922861671263 0.0001145544969356 0.0054833619795782 4786.684177624728 0.0004587343160438 0.0146748414600935 3198.984891003808 0.0001870765096339 0.0108556474005381 5802.784872232368 0.0006025738373443 0.0207316971262676 3440.523939379028 +r_3163 PI 4-P phosphatase (1-18:1, 2-16:1), ER membrane 7.498339096975157e-05 0.0023340953702041 3112.816505118716 8.13607481804183e-05 0.0032852826374642 4037.920878233692 0.0001220510839034 0.0035998123169846 2949.430846376393 0.0001103763389183 0.004124653494387 3736.9000773246576 0.0003391258699119 0.0105877415724265 3122.068385751805 0.0004189445220218 0.0102729232365591 2452.096326974802 0.0007333266287483 0.0188428573980315 2569.5040462655948 0.0009434425675321 0.0264619699746231 2804.8310395664225 0.000756744981913 0.0232163144933665 3067.917865101037 +r_3164 PI 4-P phosphatase (1-16:0, 2-18:1), ER membrane 4.701124852493096e-05 0.0018098694832551 3849.8647452329296 0.0001648985210323 0.0044538677223508 2700.9749356554657 0.0001180329999262 0.0035948869536478 3045.662616296983 0.0002545683874372 0.0063849544759617 2508.1490047681614 0.0001476732473819 0.0067174592383208 4548.8667429023 0.0001145545592647 0.0054833656870172 4786.684809590417 0.0005205126167062 0.0159257402662125 3059.626175248142 0.0006178829871248 0.0216064856803831 3496.85719312702 0.0001544015126281 0.0103926277986474 6730.910612047521 +r_3165 PI 4-P phosphatase (1-16:1, 2-18:1), ER membrane 8.836585588107537e-05 0.0024353991154441 2756.040883847395 0.0001244619096142 0.0039178515546084 3147.831787855838 4.7474940969462254e-05 0.0022752059630747 4792.435580990517 0.0001890894182996 0.0053302300228007 2818.893870810528 0.0001382605948454 0.0067035657759552 4848.50060384046 0.0001692752808153 0.0067101826875578 3964.065311389601 0.00020810503745 0.0100741962943934 4840.918998325514 0.0003113527929349 0.0152373435737249 4893.9158149473005 0.0004631898699301 0.0179965503275212 3885.3505864093327 +r_3166 PI 4-P phosphatase (1-18:0, 2-18:1), ER membrane 6.231890210459165e-05 0.0020893976982357 3352.751135970051 8.417144927968156e-05 0.00329328086363 3912.5866214887865 2.8882867681381296e-05 0.0016252820145829 5627.149050821728 5.031818004610309e-05 0.002651791085035 5270.04570237905 0.0002052401399856 0.0082065217957618 3998.497465620448 0.000121536682265 0.0054967178300974 4522.682146373028 0.0003769230332289 0.0128725782870091 3415.1742271451058 0.0004785283265114 0.0187268643149238 3913.428584561957 0.0006023589027727 0.0207648232918907 3447.250998749745 +r_3167 PI 4-P phosphatase (1-18:1, 2-18:1), ER membrane 6.0144300719832464e-05 0.0020880333529382 3471.7060934250176 6.87872129719748e-05 0.0025062249517471 3643.445988672722 0.0001041861228058 0.0033111365285933 3178.097465787093 7.627056639932288e-05 0.0033748910222056 4424.89308986641 0.0001846665233664 0.0071276496363122 3859.741065341091 0.0002342220347795 0.0077612296908645 3313.620641273488 0.0003191737377824 0.0123464429319937 3868.2515102195057 0.0004718100921944 0.0187210062670649 3967.911364504745 0.0001543966298043 0.0103926091116231 6731.11137515822 +r_3168 PI 4-P phosphatase (1-16:0, 2-16:1), Golgi membrane 5.90574461004445e-05 0.0020873695542116 3534.473113959996 0.0001075054056379 0.0037997495351787 3534.4729994096538 9.083265322170474e-05 0.0032104524940406 3534.469576931285 0.0002681252022483 0.0066984480201347 2498.253787396611 0.0005348383291658 0.0133617419118252 2498.276803134837 0.0001639675033526 0.0066926157753554 4081.672062153343 0.0009060248041699 0.0213381150944442 2355.135863415198 0.0007639387440312 0.0241481973083273 3161.0122535345818 0.0010264909308436 0.0274177263100215 2671.014958455348 +r_3169 PI 4-P phosphatase (1-16:1, 2-16:1), Golgi membrane 5.9057622242119525e-05 0.0020873699108271 3534.4631760986067 4.192419902320583e-05 0.0021778445113651 5194.71942722069 4.541626528099719e-05 0.0022705862759833 4999.500205344675 6.709120299021777e-05 0.0033542124482951 4999.481748425665 0.0004018382621768 0.0115942597164716 2885.3050612112347 0.000164149203255 0.0067000226606502 4081.66626933886 0.0001001691594659 0.0070830296309051 7071.068249619134 0.0006109132595681 0.0215925690386785 3534.4737899355628 0.0007338878417474 0.023198284672246 3161.012262719819 +r_3170 PI 4-P phosphatase (1-18:0, 2-16:1), Golgi membrane 5.9057445063634907e-05 0.0020873695458645 3534.473161877147 0.0001343788022709 0.0042477305159289 3161.0123353871286 6.812434567541815e-05 0.0027806084560723 4081.666294925925 0.0003354548620237 0.0074942435067456 2234.0542216420376 0.0003347077897177 0.0105801559016842 3161.0127480469832 5.4720878774434376e-05 0.0038693475285227 7071.062481420647 0.0005033471999079 0.0159108667905109 3161.0122780899387 0.0006111638136703 0.0216014193396059 3534.4728952256824 0.0010274430524223 0.0274430867342595 2671.008059235959 +r_3171 PI 4-P phosphatase (1-18:1, 2-16:1), Golgi membrane 4.4293076082925954e-05 0.0018078955562182 4081.666292116286 0.0001612581480165 0.0046527933054153 2885.307417109113 4.334354805537704e-05 0.0021694381575314 5005.21589686132 0.0001341819811683 0.0047426257974415 3534.472927100336 0.0001339477336433 0.0066967169410712 4999.499998187421 0.0004377665497588 0.0109364986909929 2498.249054665631 0.0003020082102839 0.0123269671002549 4081.6662198243343 0.0001527912339571 0.0108039719051428 7071.067904441743 0.0007336075998398 0.0231892815367946 3160.99254449633 +r_3172 PI 4-P phosphatase (1-16:0, 2-18:1), Golgi membrane 7.382182561842729e-05 0.002333517595074 3161.013122508859 5.37527198037464e-05 0.0026873673994525 4999.500321591643 0.0001135406711152 0.0035890346411769 3161.012354359751 0.0001338942731172 0.0047324840955399 3534.4932873979133 0.0005342491813324 0.0133472367237981 2498.316738737707 0.0002707344856515 0.0085598742891177 3161.7229214508698 0.0003020079891342 0.0123269580655166 4081.666217126473 0.0009149927238172 0.0264005951101395 2885.33388549782 0.00044033286774 0.0179729178305988 4081.666200128108 +r_3173 PI 4-P phosphatase (1-16:1, 2-18:1), Golgi membrane 4.427614060544536e-05 0.00180720466964 4081.6671121913296 0.0001595613117877 0.0046050886964653 2886.093530360245 0.0002025941777815 0.0047718936611057 2355.395260297775 0.0001677274237378 0.0053018845066136 3161.012307027943 0.0006027643974684 0.0141959205314064 2355.135869176765 0.000164141531016 0.0066997096107957 4081.666333513315 0.000100669503242 0.0071184060230453 7071.065013533355 0.0004583736526523 0.0187092824194051 4081.6661933214896 0.0010274433099692 0.0274430936454576 2671.0080623601016 +r_3174 PI 4-P phosphatase (1-18:0, 2-18:1), Golgi membrane 5.9057472003351017e-05 0.0020873705192656 3534.473197815116 0.000213911655418 0.0053445406425626 2498.480333910172 0.0001361718262332 0.0039289789336633 2885.309716662189 6.709105271075446e-05 0.0033542122871874 4999.4927067968965 0.000132821483641 0.0066406490283681 4999.679905937333 0.0003282809263134 0.0094719141451621 2885.307486953163 0.0005033470224972 0.0159108615022325 3161.012341603922 0.0007638968415095 0.024146873162786 3161.01230567576 0.001169093536427 0.0292087984899499 2498.4141627552026 +r_3175 PI 4-P phosphatase (1-18:1, 2-18:1), Golgi membrane 4.429349154797997e-05 0.0018078953592002 4081.6275620130673 0.0002150068966738 0.0053713780271207 2498.235224178765 8.917279568521728e-05 0.0031534272324251 3536.31083134016 0.0002226388065134 0.0059652095379746 2679.32155736524 0.0003342117532338 0.0105645566206355 3161.036833208816 0.0003283249052532 0.0094731800711792 2885.306572729279 0.0006040165578417 0.0174277343409931 2885.307383503656 0.0016790370435757 0.0357615444193515 2129.884183090547 0.000440332727021 0.0179729123483024 4081.6662594877785 +r_3176 PI 3,5-P2 phosphatase (1-16:0, 2-16:1), cell envelope 5.905732071164387e-05 0.0014753952375893 2498.2427577323288 5.356341297333434e-05 0.0018931620751013 3534.4313777089133 3.4062554213642935e-05 0.0013903062448208 4081.62651602915 0.0001006341815725 0.0029036016400976 2885.3035765035647 0.0001673869517192 0.0052911181692397 3161.009932311191 0.0002458835519001 0.0057908593627181 2355.122706650536 0.0002013391801085 0.0071162657477652 3534.466438141316 0.0007639561396358 0.0170671912397009 2234.053809402796 0.0005131931460103 0.0137074643351699 2671.0146933439146 +r_3177 PI 3,5-P2 phosphatase (1-16:1, 2-16:1), cell envelope 2.948617556339445e-05 0.0010417037580268 3532.854763708416 4.031470685747305e-05 0.0016455048759722 4081.649115767299 8.994971957649647e-05 0.0022478127923255 2498.965869942392 0.0001005804495017 0.0029020508621641 2885.3031344961187 0.0001339478537435 0.0047343419399346 3534.4664416935 0.0001352382376297 0.0042759697716849 3161.805304939327 0.0004023097941799 0.0100507229765301 2498.254609241153 0.0002289559936671 0.0093452260002744 4081.669079981397 0.0002935552037274 0.0103756261915327 3534.4719016350373 +r_3178 PI 3,5-P2 phosphatase (1-18:0, 2-16:1), cell envelope 4.4251987998524655e-05 0.0012767989879703 2885.291815619536 0.0001343038653101 0.0030004175614225 2234.051532689248 6.810902387360231e-05 0.0019651441581229 2885.2919134032927 0.0001004162413679 0.0028973238218385 2885.313951575973 0.0003335677443789 0.0074525908904759 2234.206099379395 8.208148401307775e-05 0.0033502808806776 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0.0130601405944391 1594.7824899304987 0.0022120538644335 0.0292320226792721 1321.4878330622337 0.0024394684180717 0.0372985292819879 1528.9613509926169 0.0034105746167854 0.0439663806811965 1289.1194482246997 +r_3205 PI 4,5-P2 phosphatase (1-16:1, 2-18:1), cytoplasm 0.0003376437034844 0.0045031551811054 1333.700328077662 0.0004825323333551 0.0073230516496314 1517.629212267033 0.0005546374120283 0.0070796934948664 1276.4543720511192 0.0007602010958419 0.0103875439733385 1366.4205471625276 0.0004650600331549 0.0093980648314482 2020.8283149364377 0.0010523892694258 0.0149743867257969 1422.8942807414894 0.0023385297205769 0.0305674869795004 1307.1241605584055 0.0032003804049268 0.044350704447665 1385.79477550199 0.0008800428096184 0.019387093309643 2202.971616579596 +r_3206 PI 4,5-P2 phosphatase (1-18:0, 2-18:1), cytoplasm 0.000286539939824 0.0040553202202502 1415.272238397479 0.000375334847233 0.0059884027212311 1595.482744375449 0.0002857631250981 0.0046967122587184 1643.5683425231475 0.0004856230640745 0.0077543190010582 1596.777330960426 0.0010347406461254 0.0168467087277504 1628.109303604953 0.0010393220563361 0.0146944055946142 1413.845256629645 0.0016102877749686 0.0246043856222499 1527.9496003581587 0.0019850121280308 0.0330148195820769 1663.2049303813578 0.0015327213705832 0.0296683263982313 1935.66338720396 +r_3207 PI 4,5-P2 phosphatase (1-18:1, 2-18:1), cytoplasm 0.0002973395774319 0.0039601312895516 1331.854751309657 0.0004666001658111 0.0066868512891855 1433.100924334362 0.0001336381544364 0.0029538370644307 2210.3246463455043 0.0006968596423771 0.0095575271158288 1371.5139368992047 0.0006860834349415 0.0130034449961251 1895.3153995379184 0.0003819493343161 0.0080728558884561 2113.593391361551 0.0008539394458726 0.0168429121876767 1972.3778154392007 0.0010665747950808 0.023769075713894 2228.5427917028974 0.0024137791071016 0.0359890765788383 1490.98467514919 +r_3208 PI 4,5-P2 phosphatase (1-16:0, 2-16:1), ER membrane 6.752644916353206e-05 0.002152094250874 3187.038971443944 5.552440783289496e-05 0.002688789371328 4842.535879752524 0.0001424234768666 0.003939056026089 2765.7350548866893 0.0001473201538999 0.0047652526067988 3234.623695841354 0.0004859561125851 0.0125333487228584 2579.1112403513325 0.0003436635652811 0.0094933184502964 2762.387232562478 0.0003134517557812 0.01233995909461 3936.79692871844 0.0010891884765426 0.028558788329291 2622.024465402304 0.001695028739552 0.0347687888819159 2051.221201777624 +r_3209 PI 4,5-P2 phosphatase (1-16:1, 2-16:1), ER membrane 6.014433228555872e-05 0.0020880465098816 3471.7261469755963 0.0001659735295559 0.0046561664875395 2805.366916035347 0.0001971308366848 0.0046128267728358 2339.982343914768 7.626993013752909e-05 0.0033748924740062 4424.931906874298 0.0005237239802282 0.0127580422086872 2436.0240680839192 0.0004628924395394 0.0109543861346643 2366.5078966431533 0.0009143903070051 0.0210319476845133 2300.106149790406 0.0011084789367336 0.0286013288066712 2580.232051224256 0.0007136147754467 0.0214302970424692 3003.0624056310826 +r_3210 PI 4,5-P2 phosphatase (1-18:0, 2-16:1), ER membrane 7.433300441727012e-05 0.0022134255753792 2977.715743808977 0.0001884697638335 0.005024850885859 2666.131045983863 0.000168596213188 0.0042406595672455 2515.275691581653 0.0002640411913707 0.0064499596793144 2442.785402470553 0.0004808851976681 0.012509630992132 2601.3757655239497 0.0004428793230246 0.0109422678426126 2470.7109304363203 0.0005090688537777 0.0159158277862296 3126.458762527045 0.0011038237150882 0.028585944656999 2589.720103514237 0.0010433511615207 0.0274398779388616 2629.975309450672 +r_3211 PI 4,5-P2 phosphatase (1-18:1, 2-16:1), ER membrane 0.0001180700732904 0.0029217275671545 2474.5708084449843 0.0001755571274183 0.0047483955930958 2704.758082410555 0.0001801318993324 0.0043317403134426 2404.76025040314 0.0002445305268658 0.0062822322413388 2569.0993766125143 0.0004052033521908 0.0115709608865299 2855.5935739345723 0.0003637439655303 0.0095047148905414 2613.023387668573 0.0007836542297177 0.019174041314478 2446.7476327389327 0.0009436201019192 0.0264670903131832 2804.8459607156806 0.0003158407772587 0.0146769747060938 4646.953706699278 +r_3212 PI 4,5-P2 phosphatase (1-16:0, 2-18:1), ER membrane 8.3921317089806e-05 0.0023924110676667 2850.778742076476 0.0002483357967111 0.0055400907416862 2230.8868938978057 0.0001066789297939 0.0033153672120801 3107.7994675079426 0.0002377686905145 0.0060455906045159 2542.635277770074 0.0003485945683625 0.0105981303975146 3040.245419570495 0.0001247803614255 0.005530622496829 4432.286005300055 0.0003191736553485 0.0123464429598564 3868.25251801393 0.0003123005107146 0.0152848405881266 4894.273324481883 0.0008873370645326 0.025387965743065 2861.141133154029 +r_3213 PI 4,5-P2 phosphatase (1-16:1, 2-18:1), ER membrane 0.0001105512966728 0.0027009567766476 2443.1705985697777 0.000178181476685 0.0047486009680042 2665.03626322324 2.4766226597221943e-05 0.0016122606806522 6509.916536227851 0.0001555998232737 0.0047764013886011 3069.6701886336364 0.0004731181370989 0.0125253791906714 2647.410489793026 0.0002772120436933 0.0086088451418248 3105.509063432964 0.0005101132423189 0.0159159646130598 3120.0845797896413 0.0006166823136351 0.0215639360123781 3496.765763439148 0.0008500843385708 0.0241333223004819 2838.932704142645 +r_3214 PI 4,5-P2 phosphatase (1-18:0, 2-18:1), ER membrane 9.184733763587136e-05 0.0025576019495718 2784.6228485265897 3.041919488462804e-05 0.0019045159126634 6260.901775628143 0.0001511954526124 0.0039872788585688 2637.168505846877 0.0002012727604352 0.0055598010685203 2762.3216656322425 0.0005503025099278 0.0132353912434768 2405.111916573255 0.0005267047126592 0.0117313340564738 2227.3075927580267 0.0008669742501885 0.0204357225502609 2357.1314310449834 0.0016829602498273 0.0354424499253647 2105.958826359697 0.0011893969700954 0.0293424480356273 2467.002083692298 +r_3215 PI 4,5-P2 phosphatase (1-18:1, 2-18:1), ER membrane 8.967357916029625e-05 0.0025565237653771 2850.9219653284754 0.0002167570942606 0.0052010171911295 2399.4680353465974 0.0001918459168623 0.0045333222848841 2363.001704194316 0.000248349567274 0.0062902132360695 2532.806199387311 0.0004520396276655 0.0118326857518101 2617.62133840296 0.0004530892981872 0.0109533939783895 2417.491214692536 0.0006194678196578 0.0173921518479763 2807.595696832434 0.0010829749982199 0.0285748555763277 2638.5517323387594 0.0011084497962961 0.0279315892248919 2519.8786014687853 +r_3216 PI 3,5-P2 phosphatase (1-16:0, 2-16:1), vacuolar membrane 3.690187335410847e-05 0.0015652933446578 4241.77203590002 0.0002025297428014 0.0051266073467939 2531.286158705224 0.00014745072515 0.0040076624536931 2717.967273213372 8.386375211368473e-05 0.0035574044921536 4241.885680635086 0.0004353301302112 0.0118325927809139 2718.07347108549 0.0003420711023884 0.0095221520305878 2783.6762486221937 0.0003020083189953 0.012326971084887 4081.6660699590784 0.0006111467683858 0.021600817061415 3534.472925131954 0.0002935188692551 0.0146744765313779 4999.500225868885 +r_3217 PI 3,5-P2 phosphatase (1-16:1, 2-16:1), vacuolar membrane 1.4764343748437978e-05 0.0010439977580516 7071.074582384108 0.000201569766995 0.0051135698077937 2536.873403201551 0.0001362435141875 0.0039310445727547 2885.307675888974 0.0001677273889403 0.0053018838555576 3161.012574662962 0.0002009214794454 0.0082009410319355 4081.6646655050185 0.0001641624583253 0.0067005637956246 4081.666334664618 0.0004635881457894 0.0146707360083283 3164.605510640554 0.0005942564951395 0.0210293462789525 3538.765911849801 0.0011669365460558 0.029156796539807 2498.576005555379 +r_3218 PI 3,5-P2 phosphatase (1-18:0, 2-16:1), vacuolar membrane 0.0001313907130135 0.0030954680735591 2355.926079219116 0.0001341381424144 0.0042401523240885 3161.034026389485 5.676501766480744e-05 0.0024078791940827 4241.836421686782 0.0002348185856963 0.0062720195622603 2671.0064468112178 0.0004701893625758 0.0120073421667023 2553.7247590891434 0.000158703142147 0.0064796508299578 4082.874946454032 0.000704633748756 0.0188208246798983 2671.0081248767046 0.0006111646531857 0.0216014492854834 3534.4729399654134 0.000587110373086 0.0207512567708484 3534.4728558911547 +r_3219 PI 3,5-P2 phosphatase (1-18:1, 2-16:1), vacuolar membrane 8.854930267698194e-05 0.0025549116429592 2885.2984334379644 0.0002594773301667 0.0058302380038001 2246.91613716448 9.083256641420748e-05 0.0032104538344401 3534.474430459291 0.0001341447799743 0.0047413116248697 3534.4734441233286 0.0001338424329573 0.0066914524227147 4999.499990297605 0.0004363922404011 0.0109024537349715 2498.31521407195 0.0005033470416819 0.0159108618324839 3161.012286734902 0.0007639561616881 0.0241487480956763 3161.0122814266306 0.0006783875388501 0.0217254728882356 3202.5165033337908 +r_3220 PI 3,5-P2 phosphatase (1-16:0, 2-18:1), vacuolar membrane 6.644006921576887e-05 0.0021514464882768 3238.1761693984267 8.062927229379774e-05 0.0032910098010965 4081.656335809064 0.0001816651457627 0.004538447383682 2498.248832832298 0.0002488097358283 0.0063119536212061 2536.859580752408 0.0003682186486969 0.0108415963756757 2944.3365820940594 0.0002736041684597 0.0086486614057947 3161.012295420349 0.00025165819909 0.0106749827188092 4241.857709149302 0.0006875603895369 0.0222645675031195 3238.198104767685 0.0004401344449466 0.0179648228379151 4081.667100626724 +r_3221 PI 3,5-P2 phosphatase (1-16:1, 2-18:1), vacuolar membrane 9.596816515435452e-05 0.0026084796775987 2718.067677342045 0.0001208929602491 0.0039146576752991 3238.1188013198303 0.0001362488171887 0.0039311978438028 2885.307869027754 0.0002520383711429 0.0063826130962785 2532.397375580448 0.000133947647266 0.0066967136731246 4999.500782440299 0.0001641623678979 0.0061163800624931 3725.811305484184 0.0003020083328316 0.0123269729022884 4081.6664847320367 0.0008403517022283 0.0247432140891375 2944.387929901957 0.0009540542783846 0.0259319035353938 2718.074235702952 +r_3222 PI 3,5-P2 phosphatase (1-18:0, 2-18:1), vacuolar membrane 7.175085520763394e-05 0.0022718304230218 3166.276438723334 0.0001612581591541 0.0044544675566871 2762.3207284844243 5.67292624273359e-05 0.0024061988580433 4241.547933265308 0.0001339382812752 0.0047340376083774 3534.491829598999 0.0008371728652082 0.0165556776494478 1977.569787254155 0.0004104062385511 0.0104114874676235 2536.8735875892103 0.0009025688689143 0.0212578184390662 2355.2572187245305 0.0008401373562359 0.0247366057346035 2944.352557471128 0.0013209983598295 0.0311113065453366 2355.135895047718 +r_3223 PI 3,5-P2 phosphatase (1-18:1, 2-18:1), vacuolar membrane 0.0001609662373586 0.0034297558112192 2130.72993908514 0.0002015726861185 0.0051136463970523 2536.874660709637 0.0001021866338735 0.0033090058103164 3238.19827004958 0.0002180456822301 0.0059266442441129 2718.0745720332875 0.0003683560606918 0.0108458315791939 2944.387981243862 0.0003009646019528 0.0088615627076369 2944.3870309454005 0.0004507747389944 0.0145933672811309 3237.3968678202687 0.0017421149552772 0.0360564215972972 2069.692444122298 0.0005871104356228 0.0207512596574725 3534.4729710788024 +r_3224 DGPP phosphatase (1-16:0, 2-16:1), vacuolar membrane 0.0001033499904713 0.0027604892815831 2671.010678368774 8.06293680269402e-05 0.0032910080880627 4081.6493649846143 0.0001361775710614 0.003929143571275 2885.308895325911 0.0002012728809327 0.0058073436893796 2885.308573348983 0.0004688165933783 0.0125221312955649 2671.008550556636 0.0002188831354828 0.007736367101971 3534.473811746194 0.0001006693161646 0.007118402281093 7071.074436874065 0.0007638691155899 0.024146000838189 3161.0128417798487 0.0005871102220005 0.0207512580408626 3534.4739817598097 +r_3225 DGPP phosphatase (1-16:1, 2-16:1), vacuolar membrane 1.476427989678413e-05 0.0010439988031625 7071.112241579484 0.0002150108278325 0.0053715079458067 2498.2499718529984 0.0001135407624616 0.003589035544059 3161.010606452748 -9.520000000000091e-11 2.9381835518763216e-10 -308.6327260374258 0.0003348689149263 0.0105852504898463 3161.0131660542365 0.0003830457973034 0.0102311828659967 2671.0077327624285 0.000401705342901 0.0141982881319227 3534.5031832002883 0.0012223296612402 0.0305368422908866 2498.249306975081 0.0013209978792439 0.0311112990384483 2355.136183583769 +r_3226 DGPP phosphatase (1-18:0, 2-16:1), vacuolar membrane 2.9528619683617096e-05 0.001476288140613 4999.516253826437 0.0001611715591436 0.0046502914059474 2885.305218027629 0.0001589568988106 0.0042457540497409 2671.0096142460425 0.0001006363701131 0.0041076444403316 4081.669912888056 0.0001339475943038 0.0066967145911764 4999.50344459894 0.0003283248643933 0.0094731825959673 2885.307700795145 0.0007014306844826 0.0187364851146783 2671.1812769492903 0.0010695383111831 0.0285674579546498 2671.0083833319404 0.0005871100823474 0.0207512534055326 3534.474032972057 +r_3227 DGPP phosphatase (1-18:1, 2-16:1), vacuolar membrane 8.823953055618485e-05 0.0025460684861032 2885.405747350513 0.0001612580400133 0.0046527934361851 2885.309430648412 0.0001362489424712 0.0039311977576606 2885.305152728386 0.0002011579071827 0.0058040280730531 2885.3094339365057 0.0002009213872961 0.0082009444902783 4081.668258734655 0.0004089657859164 0.0103924900566454 2541.1636901009056 0.0002515867246486 0.010671614659369 4241.724071200601 0.0004582955485223 0.0187061002201395 4081.667448102696 0.0005871104007004 0.0207512567509754 3534.472686264744 +r_3228 DGPP phosphatase (1-16:0, 2-18:1), vacuolar membrane 7.371673838456715e-05 0.0023302076271466 3161.0292020657816 0.000187894096744 0.0050186934613635 2671.022426106241 0.0001323235900454 0.0038226434671693 2888.860154002477 0.0001670497733042 0.005280587253206 3161.08615339948 0.0001339475012455 0.0066967102463196 4999.50367423711 0.0002736040071101 0.0086486597357207 3161.013549131844 0.0008053554041209 0.0201197862495241 2498.249362526484 0.0007639560212558 0.0241487475626154 3161.0127927151966 0.0003119840860495 0.0147336636902591 4722.56898639326 +r_3229 DGPP phosphatase (1-16:1, 2-18:1), vacuolar membrane 0.0001032639269217 0.0027581893588724 2671.009558801405 0.0001612580030878 0.0046527917511159 2885.3090463862736 0.0001361774212794 0.003929142554268 2885.3113220615824 0.0002012728595669 0.0058073433126789 2885.3086924749205 0.000334856298211 0.0105848375264422 3161.0089411456647 0.000109442021912 0.0054715346818105 4999.482453099482 0.000503347061274 0.0159108655518888 3161.0129026313634 0.00076395605204 0.0241487486179746 3161.0128034836616 0.0007338877585997 0.0231982880527093 3161.013081478886 +r_3230 DGPP phosphatase (1-18:0, 2-18:1), vacuolar membrane 0.0001033504414883 0.0027605015104072 2671.0108545780035 0.0001612174206624 0.0046515899924618 2885.2899229791733 6.812434404430621e-05 0.0027806125940895 4081.672466866111 0.0002683634952742 0.0067043908178663 2498.249924422402 0.0002007321557758 0.0081932279237389 4081.671863718255 0.0001641608723663 0.0067005038287726 4081.669238342468 0.0004946279533655 0.0156449766121089 3162.9786601542287 0.0004583734380563 0.0187092791677399 4081.667394837521 0.0002935549392256 0.0146762885574702 4999.503192207727 +r_3231 DGPP phosphatase (1-18:1, 2-18:1), vacuolar membrane 8.85861044019375e-05 0.002555984300248 2885.310644941492 0.0001075052960691 0.0037997499188368 3534.476958599592 0.0001135406285425 0.0035890366463112 3161.0153056056783 0.0001677273111686 0.0053018840032995 3161.0141284441124 0.0005357905038036 0.0133853826452823 2498.2493251106584 0.0003283247120702 0.0094731803404891 2885.30835244072 0.0006038179545281 0.017422011524628 2885.308625551429 0.0007639558738574 0.0241487424287012 3161.012730587207 0.000733698558565 0.0231923105426077 3161.0135077772698 +r_3232 DGPP phosphatase (1-16:0, 2-16:1), Golgi membrane 0.0001328634478881 0.0031291150634854 2355.1361290276245 0.0001075054101575 0.0037997498717883 3534.473163926836 2.270815036102684e-05 0.0016057090503277 7071.069306831553 0.0003353413687317 0.0074917111055758 2234.0551462256635 0.0004018428022982 0.0115944000568712 2885.307386510329 0.0002735611649849 0.0086473026659846 3161.012516692122 0.0004021163127038 0.0142127295852295 3534.482222236253 0.000762289665642 0.0240963005076757 3161.042526711992 0.0010274429261853 0.0274430834587496 2671.0080686076976 +r_3233 DGPP phosphatase (1-16:1, 2-16:1), Golgi membrane 8.858640972798523e-05 0.0025559830103343 2885.2992441874544 0.0001060972866295 0.0037504281965386 3534.8954866623203 0.0001134581958413 0.0035864317733364 3161.016043609931 0.0001336208745689 0.0047229054802171 3534.556629308436 0.0002678952795912 0.0094686871703452 3534.4733153914203 0.000109441582143 0.0054715324926217 4999.500542190084 0.0003020085037445 0.0123269721721734 4081.6639330792186 0.0009167108726273 0.0264499265609251 2885.307390880939 0.0010274429700441 0.0274430850421359 2671.008108698817 +r_3234 DGPP phosphatase (1-18:0, 2-16:1), Golgi membrane 4.429307001154191e-05 0.0018078960027046 4081.667859630216 0.0001343457185821 0.0042466856010951 3161.012978988008 6.806837750257118e-05 0.0027783254559415 4081.668401507889 0.0001677273634953 0.0053018830453263 3161.012571137821 0.0002009215357111 0.008200943719491 4081.664860098844 0.0003828961073696 0.0102271910583777 2671.0094100029914 -2.279999999999997e-11 1.492803299948865e-10 -654.7382894512576 0.000611164711665 0.0216014516660953 3534.4729912896987 0.0005871103632269 0.0207512573303385 3534.47301053978 +r_3235 DGPP phosphatase (1-18:1, 2-16:1), Golgi membrane 7.382180923001274e-05 0.0023335170035616 3161.013022982 8.057303721415915e-05 0.0032887240391117 4081.668201696876 0.0001362377545786 0.0039308783921706 2885.307677250274 6.709097198499718e-05 0.003354213940769 4999.501187013846 0.0002009213684933 0.0082009409823667 4081.666894796947 0.0003830456851445 0.0102311816499205 2671.008197380106 0.0007044132291926 0.0188149405978202 2671.008978548511 0.0010695384617711 0.0285674589717796 2671.0081023614284 0.0004403326538225 0.0179729099895375 4081.666402323783 +r_3236 DGPP phosphatase (1-16:0, 2-18:1), Golgi membrane 5.903599516953332e-05 0.0020866124562867 3534.4749424392376 0.0001612003116901 0.004651126270045 2885.3084843808024 9.083317802118743e-05 0.0032104511106212 3534.4476330800703 0.0001338053494739 0.0047293377741781 3534.4908053152303 0.0005347966689493 0.0133607005186124 2498.276689879456 -1.939999999999998e-11 1.3794000684753668e-10 -711.0309631316335 9.843179508220544e-05 0.0069601813833429 7071.070254819754 0.0003055823384193 0.0152775897975464 4999.500257957539 0.0005870837223702 0.0207503158509684 3534.4730334528576 +r_3237 DGPP phosphatase (1-16:1, 2-18:1), Golgi membrane 7.3821809602235e-05 0.0023335171039249 3161.01314299709 0.0001343796636057 0.0042477459231594 3161.0035396584303 0.000113540691435 0.0035890357264733 3161.012744515125 0.0001341390541806 0.004741109927403 3534.4739504556574 0.000598897658518 0.014106892775587 2355.4763614359467 0.0002188832564492 0.0077363671046393 3534.471859628684 0.0004026466916204 0.0142314395577125 3534.4732376761103 0.0003055823409932 0.015277589786189 4999.500212130019 0.001027443355183 0.0274430943639025 2671.008014744951 +r_3238 DGPP phosphatase (1-18:0, 2-18:1), Golgi membrane 4.4284414896378136e-05 0.0018075429623265 4081.6683850426616 0.0001343817557052 0.0042478246170348 3161.012888052471 4.541634773701847e-05 0.0022705861662098 4999.490886756337 0.0001340511847948 0.0047380102949918 3534.4784921100936 0.00033486916312 0.010585256477908 3161.012611397734 0.0003282834897258 0.009471985168207 2885.30659160419 0.0007046858951823 0.0188222179083733 2671.00818067366 0.0012222879527943 0.0305357976961684 2498.249093133865 0.0010258844730408 0.0274016243262881 2671.024374222685 +r_3239 DGPP phosphatase (1-18:1, 2-18:1), Golgi membrane 0.0001328563745162 0.0031289491032634 2355.136601202239 5.375313306779238e-05 0.0026873657319442 4999.458782346614 0.0001362487806556 0.0039311968362779 2885.30790320498 0.0001677281814843 0.0053018839147247 3160.997673618895 0.0006027644975779 0.0141959222428664 2355.135761961624 0.0004924903470376 0.0115987477850828 2355.121852611018 0.0002013387718376 0.0100659335568563 4999.500823902686 0.0016807035740633 0.0357968618384593 2129.873607153441 0.0008806655009916 0.0254099072947357 2885.3074483018804 +r_3240 lysoPA phosphatase (16:0), cytoplasm 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3241 lysoPA phosphatase (16:1), cytoplasm 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3242 lysoPA phosphatase (18:0), cytoplasm 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3243 lysoPA phosphatase (18:1), cytoplasm 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3244 lysoPA phosphatase (16:0), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3245 lysoPA phosphatase (16:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3246 lysoPA phosphatase (18:0), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3247 lysoPA phosphatase (18:1), vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3248 lysoPA phosphatase (16:0), Golgi membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3249 lysoPA phosphatase (16:1), Golgi membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3250 lysoPA phosphatase (18:0), Golgi membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3251 lysoPA phosphatase (18:1), Golgi membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3252 ergosteryl ester hydrolase (16:1), lipid particle 4.3969430507127856e-05 0.0013842247355665 3148.1525223351982 0.0001131551068011 0.0030038602505921 2654.639578813251 1.7254546702565073e-05 0.0007703324390612 4464.518554675906 8.3000102517251e-05 0.0028209871102707 3398.7754529393205 0.0003984625040996 0.0088488655938759 2220.7523927174534 0.0002306765017608 0.0060054861138785 2603.423438467404 0.0001952144911124 0.0074076051673811 3794.597995860474 0.0006460142898371 0.0171410273334438 2653.351110509532 0.0002740895593991 0.0107864594562745 3935.3777210342378 +r_3253 ergosteryl ester hydrolase (18:1), lipid particle 4.394766133809632e-05 0.0013773169029974 3133.9936211884283 0.000129098166919 0.0032176300560985 2492.390196458506 0.0001374916085481 0.0030361770283733 2208.263515450235 0.0002024809087633 0.0044673620786439 2206.31273631139 0.0001675001848403 0.0056841691710625 3393.5300886257983 0.0003325030970021 0.0072916093216873 2192.944783801562 0.0006004054570743 0.0132765889012539 2211.270524746548 0.0007349732708756 0.0182508938773547 2483.205117869323 0.0013216194318455 0.0239735562467457 1813.953069172749 +r_3254 episteryl ester hydrolase (16:1), lipid particle 6.125447316724851e-05 0.0016345407528774 2668.44308400872 0.0001814312570864 0.0037164928764811 2048.4303179969065 3.5624041681078026e-05 0.0011020081588447 3093.439449432572 8.054454225546658e-05 0.0027884615141889 3462.0117466738507 0.0002794327320996 0.0074636176982431 2670.9890577822835 0.0002827464125689 0.0066850499971126 2364.327078945018 0.000313913629906 0.0095628179240057 3046.321348603617 0.0005966647835321 0.0160383993701235 2688.0083780342807 0.0002663397137094 0.0107843948484791 4049.112578173036 +r_3255 episteryl ester hydrolase (18:1), lipid particle 7.41580764915811e-05 0.0017636932831126 2378.288874999114 0.000103401171181 0.0028099253742756 2717.498595208909 0.000100278212996 0.0025543237494921 2547.237005104234 0.000139119146292 0.0037162589599262 2671.277864316962 0.0004803458533415 0.0097669296942269 2033.311961846213 0.0001310799134555 0.0046029470488953 3511.5578943796445 0.0007453346531473 0.0146503610419696 1965.6084659562405 0.0007326888607506 0.0183044270451317 2498.2537644121444 0.0008330125553039 0.0186748364332733 2241.843332896565 +r_3256 fecosteryl ester hydrolase (16:1), lipid particle 4.35648749880563e-05 0.001373541294108 3152.8640779633283 0.0001130142845882 0.0029683935418156 2626.564909586236 1.842444672315632e-05 0.000774507499084 4203.694747102857 0.0001698243533654 0.003935660398029 2317.488817142398 0.0002407849496674 0.006947414353034 2885.319187361486 0.0001563463618065 0.0045908405095759 2936.3270475443014 0.0004109278812936 0.0108903247473619 2650.179080834678 0.0006232508517689 0.0166400822689148 2669.8852029941 0.001269644136911 0.0232118761881111 1828.2190665318235 +r_3257 fecosteryl ester hydrolase (18:1), lipid particle 0.0001038469676735 0.0021233181539359 2044.6607171148223 9.675760721215151e-05 0.0027874030669627 2880.81025076514 0.0001255978589822 0.0028447376800467 2264.957144253292 0.0001886603611747 0.0042735919818577 2265.230467728601 0.0004222019755432 0.009062376098935 2146.4551621946284 0.0004785425885533 0.0087469961323361 1827.8406857745304 0.0004636517536904 0.0116076645150994 2503.530812232911 0.0010924181574307 0.0222789923918174 2039.419817427344 0.0009425562720431 0.0201346791817627 2136.1779427892047 +r_3258 lanosteryl ester hydrolase (16:1), lipid particle 3.562125839743882e-05 0.0012524496460469 3516.0174075630016 9.059697968157156e-05 0.0026265895260541 2899.202087405151 4.858718502143391e-05 0.0013301470645107 2737.649987180615 7.172825410316032e-05 0.0025738171132647 3588.289085585532 0.0002575266154233 0.0068509702476601 2660.29599946306 0.0003416661509991 0.0072279926753925 2115.513244216543 0.0005299796106949 0.0121783012517323 2297.881089380818 0.0012562014125423 0.0237343962478049 1889.3782486496125 0.0005306307135984 0.0152409601078715 2872.2348174147755 +r_3259 lanosteryl ester hydrolase (18:1), lipid particle 3.905091198874504e-05 0.0012514750598642 3204.7268453677666 2.6983170982113263e-05 0.0013627110872588 5050.225891398028 0.0001050112662926 0.0026276965546078 2502.2996554349056 9.977068080747588e-05 0.0031540345309427 3161.2839617973623 0.0002257664454761 0.0065753554686317 2912.4591365929955 0.0001969806799498 0.0054011399756955 2741.96432719662 0.0002362880746022 0.0083568459009292 3536.719284287944 0.0009667596552548 0.0206425997675807 2135.235956049402 0.000671900064028 0.0169050217951749 2516.002408725622 +r_3260 zymosteryl ester hydrolase (16:1), lipid particle 7.96098629637813e-05 0.001873356156924 2353.170935335444 0.0002262134555923 0.0041597430113251 1838.857463378372 3.4421312214475154e-05 0.001090507259855 3168.116465346174 0.0002655033021555 0.0050593276831147 1905.5611143209835 0.0003563229447462 0.0083880582844822 2354.0606655167176 0.0002881758046572 0.0067987953825237 2359.2526758485624 0.0002307279614213 0.0074113047219592 3212.139818816796 0.0009308002242276 0.0199305580890267 2141.228329157708 0.0003780837519831 0.0122563354209783 3241.698527559433 +r_3261 zymosteryl ester hydrolase (18:1), lipid particle 0.0001038125536888 0.0021122663138769 2034.6925673446813 0.000166837811572 0.00360755492508 2162.312542395621 0.0002018343035814 0.0036220508592637 1794.5665305610407 0.0001569745341363 0.0039022079332005 2485.885978047802 0.0001515097904205 0.0052111525513956 3439.4823838978937 0.0002790433731459 0.0066597024028961 2386.619086421404 0.0010826107443883 0.0176219851416611 1627.7304869736568 0.0008024729113595 0.0189483965812102 2361.250618305327 0.0006590726345254 0.0165255652034044 2507.396656713642 +r_3262 zymosteryl ester hydrolase (16:1), cell envelope 4.434532953730712e-05 0.0014001103784517 3157.289376491882 0.0001917945831167 0.0039124212919604 2039.901872295961 0.0001886375870907 0.0035530493808786 1883.532033925949 0.0001990198945854 0.0043982566545295 2209.958287682768 0.000319302386772 0.0079782832949032 2498.66071329995 0.0003289031180771 0.0073349743853922 2230.1322128762363 0.0007715292965263 0.0151194257405015 1959.669685723396 0.0010084387846766 0.0214645813289074 2128.4962116753586 0.0003541222725917 0.0124508382097588 3515.971508551152 +r_3263 zymosteryl ester hydrolase (18:1), cell envelope 8.853324117922175e-05 0.0019778810913076 2234.0547628927006 0.0001290030198958 0.0032228058077987 2498.2405918865093 6.767605351421142e-05 0.0021393060181777 3161.097474054845 0.0002082235342284 0.0044878988712228 2155.3273926759766 0.0001562430905428 0.005529235191706 3538.867013252414 0.0001662915788096 0.0051745012604864 3111.7037299947788 0.0003390049132298 0.009895122210748 2918.8728023059703 0.0001826939918668 0.009133807039624 4999.511448784552 0.0009234540446505 0.0196944389824704 2132.6929148839085 +r_3264 TAG lipase (1-16:0, 2-16:1, 3-16:0), lipid particle 7.180833230528037e-05 0.0017178775139933 2392.3094421550663 0.0001288120852213 0.0031949256874077 2480.299641077001 0.0001483909052307 0.0031333699635221 2111.5646937054344 0.0002208670759856 0.0045762417399853 2071.9438239324827 0.0004517658427007 0.0092502325391939 2047.57236268566 0.0005451324174003 0.0091327226747707 1675.3218820341915 0.0006016112591287 0.0133128418574075 2212.864479412656 0.0015446715891686 0.0264546779995683 1712.6409383762275 0.0008418446508186 0.0189350860208107 2249.2375526051983 +r_3265 TAG lipase (1-16:0, 2-16:1, 3-16:1), lipid particle 8.924289408710727e-05 0.0019694203752025 2206.80917550733 0.0001285872627164 0.0032077116893056 2494.579650846315 2.9567654335722483e-05 0.0013661835918205 4620.5342375433065 0.0001194341334438 0.0034256475319681 2868.2315793571497 0.0002673085120807 0.0071881049210686 2689.066975501401 0.0002249336397139 0.0059559068065406 2647.8506345754413 0.0005503015225263 0.0127243227050237 2312.245593399014 0.0005998817845491 0.0160564654143098 2676.6049291488457 0.0005289084472485 0.0152206302609815 2877.743840198013 +r_3266 TAG lipase (1-16:0, 2-16:1, 3-18:0), lipid particle 8.796517072403985e-05 0.0019645788066434 2233.3598519425955 0.0001106349056538 0.0026833752922539 2425.432802056752 0.0001094263615062 0.0027198711032074 2485.57209228902 0.0002566044492197 0.0049225191862462 1918.3296319352248 0.0003110773578893 0.0076051892516166 2444.7903580052675 0.000264058770651 0.0061188224853014 2317.219939415152 0.0004441706448286 0.0112788824864819 2539.3129009758977 0.0005193666483456 0.0137330560384204 2644.1928995948488 0.0009791236226393 0.0204493008367976 2088.531045923972 +r_3267 TAG lipase (1-16:0, 2-16:1, 3-18:1), lipid particle 6.283704688380857e-05 0.001653710032084 2631.743715044255 8.186502610389547e-05 0.0025486622208437 3113.2491396377472 0.0001027586431942 0.0025287731803207 2460.8861130443806 0.0001855471363636 0.0042552382762482 2293.346240552843 0.0004033546068169 0.0089246722181345 2212.6119467339595 0.0003558260191832 0.0074050787567464 2081.0953548996868 0.0003020559227132 0.0093098688840917 3082.167302155148 0.0009519634515459 0.0203266703642125 2135.236424381972 0.000575780363969 0.0155071370860947 2693.23826523005 +r_3268 TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle 7.278567035242029e-05 0.0017344374403973 2382.938059097922 0.0001452039875964 0.0033903936622764 2334.917737727527 0.0001655444844453 0.0032731190252702 1977.1839794219247 9.382791279401868e-05 0.0028431127956887 3030.135394709551 0.000356559440444 0.008200618994884 2299.9304084254195 0.0003597129512225 0.0076070569241134 2114.7575860859783 0.0006034995721464 0.0134401355850686 2227.0331588251383 0.0009200746153097 0.020479936273427 2225.8995012628857 0.0011950593267106 0.0226337219246761 1893.9412813064444 +r_3269 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 7.351619067398274e-05 0.0017709626172979 2408.942303813704 0.0001287735400418 0.0032045367768344 2488.505616754145 8.314963288258221e-05 0.0023472128594498 2822.8781993114217 0.0001206196106387 0.0034470922860215 2857.8207704098763 0.0001987568717812 0.0062589481439759 3149.047420541809 0.0002974238247762 0.0069572947762978 2339.1854305996944 0.000324462797338 0.0095968429033094 2957.7637196143064 0.0004593538340052 0.014305889346799 3114.3507004308963 0.0002687540504446 0.0107844393694771 4012.754171197078 +r_3270 TAG lipase (1-16:1, 2-16:1, 3-18:0), lipid particle 7.975845415629595e-05 0.0018767179959132 2353.001967961363 0.0001230696992442 0.0027528906755515 2236.854963047228 0.0001700259894522 0.0033164243523348 1950.53965750687 0.0002355536131343 0.0047971442018506 2036.5402754889035 0.0004575632123482 0.0094362890853209 2062.2919043017264 0.000177717657224 0.0046814737830624 2634.219838470872 0.0005364355417874 0.0126227912290684 2353.086297564695 0.0010536380302954 0.0197845432937928 1877.736255234164 0.0008381644327335 0.0187050077656893 2231.663267395679 +r_3271 TAG lipase (1-16:1, 2-16:1, 3-18:1), lipid particle 7.129136481234497e-05 0.0017603752614564 2469.2685658216587 0.0001142812785632 0.0030149490946498 2638.182852479916 0.000137752855157 0.0030108490225801 2185.6890146830297 0.0002403044454259 0.00483055618721 2010.1817836316684 0.0003255712267628 0.0079863759310422 2453.034935074491 0.0001014598674499 0.0040125518339447 3954.8167514848815 0.0005430113803908 0.0125174889526975 2305.1982711093774 0.0006557513318133 0.0161124222215897 2457.09332789821 0.0009574553421117 0.0202088901133162 2110.68748843612 +r_3272 TAG lipase (1-18:0, 2-16:1, 3-16:0), lipid particle 4.427535391378653e-05 0.0013232803709829 2988.75165077093 0.0001607607534859 0.0035848007844818 2229.8979736966926 7.938383206887514e-05 0.0021768896664033 2742.233033692041 0.0002904084583909 0.0053260723429999 1833.993531906656 0.0003047550401137 0.0075553205476316 2479.145396516681 0.0003869471018788 0.0076285786126542 1971.4784205936128 0.0005576561552806 0.0126997748084971 2277.34862930113 0.0005359365295732 0.0154693255126736 2886.409986830068 0.000449890825941 0.0139074963759939 3091.3047286315427 +r_3273 TAG lipase (1-18:0, 2-16:1, 3-16:1), lipid particle 8.751497887351494e-05 0.0019537045514039 2232.423039520588 0.0001120933602212 0.0029888978283893 2666.4361051261403 8.220722856122178e-05 0.0023483721015761 2856.649156864855 0.0001661484868146 0.0040334095840188 2427.5933301262794 0.0004300935821675 0.0091555031770328 2128.7235049849646 0.0002477855852272 0.0062322724622771 2515.1876597510527 0.0004274043888109 0.011196078858619 2619.55168260362 0.000635727519501 0.0169634239434524 2668.3482188666853 0.0005316897852902 0.0152363939513843 2865.6548184516982 +r_3274 TAG lipase (1-18:0, 2-16:1, 3-18:0), lipid particle 8.645791652626233e-05 0.001933334036966 2236.156172441157 0.0001188103664185 0.0027421191556058 2307.979714451079 0.0001592472947137 0.0032440084203441 2037.0885585066503 9.67558726386024e-05 0.0030561247265579 3158.5935232820807 0.0004124928510065 0.0089881790000356 2178.990248704223 0.0002148406312705 0.005563095716156 2589.4057763914634 0.0006759227960388 0.0139027113403248 2056.849010242044 0.0006453181031941 0.0147302451469372 2282.633181066375 0.0012565869290642 0.0229527033343651 1826.590966647797 +r_3275 TAG lipase (1-18:0, 2-16:1, 3-18:1), lipid particle 7.47835660109496e-05 0.0017513538182551 2341.8966380911547 7.956041962767246e-05 0.0024887129270664 3128.07918650142 0.0001327031755522 0.0028581861997428 2153.8189932899045 0.0001516368029164 0.0037513918723972 2473.932317383917 0.0003205940526485 0.0078181142493181 2438.633588093531 0.000259440117124 0.0063356993675598 2442.066183823906 0.0006068168638857 0.0131428794536364 2165.8724791323616 0.0005307768931398 0.0151146302310872 2847.642847011803 0.0005346369177278 0.0151374111776131 2831.3441656717164 +r_3276 TAG lipase (1-18:1, 2-16:1, 3-16:0), lipid particle 6.212790986885902e-05 0.0015298937928894 2462.490362413325 0.0002038561368712 0.003984706534305 1954.665969571272 0.0001354174857329 0.0029206351479741 2156.7636794948203 0.0001855359434057 0.004133265740628 2227.743942632498 0.0004509335473881 0.0092828136035225 2058.5768473623107 0.0002983320683232 0.0066457297700803 2227.628363062993 0.0005677575312469 0.0126847413861432 2234.182848844618 0.0012518389913507 0.0236389354849363 1888.336730862648 0.0007372950956466 0.0176915218281816 2399.517090598068 +r_3277 TAG lipase (1-18:1, 2-16:1, 3-16:1), lipid particle 7.071110921618981e-05 0.0017603583993059 2489.507545305069 0.0001131935652296 0.0030132578105707 2662.039846926389 9.55990786644781e-05 0.0025474653121576 2664.738350772605 0.0001977367964906 0.0044096932251951 2230.082262612392 0.0002259994497778 0.0065242326278317 2886.8356247081847 9.973890602494155e-05 0.0040205455755484 4031.0704576437447 0.0005493732370596 0.0127103404797607 2313.607511678042 0.0010765601936229 0.0219631466420817 2040.122491262534 0.0004420716469238 0.01391827573532 3148.4208119135487 +r_3278 TAG lipase (1-18:1, 2-16:1, 3-18:0), lipid particle 0.000132360151477 0.0024127926690851 1822.89959792307 8.326846691064397e-05 0.0022037708657831 2646.585133058877 0.0001198279097513 0.002814078424741 2348.433207739887 0.0001719777187691 0.0040828872492522 2374.079199603741 0.0003688820127359 0.0084476587685708 2290.070666746464 0.000364887937749 0.0073222175966875 2006.703110510552 0.0007439670365123 0.0146870274200897 1974.150291515695 0.0006964561118568 0.0167374179978777 2403.226522523072 0.0009400312806949 0.0198061580921606 2106.967980631168 +r_3279 TAG lipase (1-18:1, 2-16:1, 3-18:1), lipid particle 0.0001076435952585 0.0021594682113438 2006.1279132836416 0.0001749675761144 0.003719105039132 2125.596708671892 6.302613149756139e-05 0.001988003517214 3154.25279955662 0.0001818786528758 0.004201784888042 2310.213332682718 0.0002457988331065 0.0069499246611839 2827.484806720036 0.0003554201131182 0.0075120975444658 2113.5825653082475 0.0006548883748569 0.0137990581338766 2107.085522306271 0.0007711236358574 0.0182506568710099 2366.761440364503 0.0007477273058989 0.017628686447882 2357.6357729356164 +r_3280 TAG lipase (1-16:0, 2-18:1, 3-16:0), lipid particle 5.783046061612003e-05 0.0015518479094931 2683.4437992710414 0.0001576555700942 0.0035045735905671 2222.930397240484 0.0001310863089898 0.0028671144315281 2187.1959425990626 0.0001859294844536 0.0041368752651122 2224.970007994602 0.0002780682042381 0.0073094943513275 2628.6695997313 0.0003024938001214 0.0066877821303283 2210.882380942097 0.0005645038454064 0.0126363379395443 2238.485714910519 0.0007919254114096 0.0187299973894439 2365.121401534966 0.000787957460585 0.0185591938765041 2355.354800844743 +r_3281 TAG lipase (1-16:0, 2-18:1, 3-16:1), lipid particle 3.5673528102583543e-05 0.0012524354098399 3510.82574798435 0.0001284553249803 0.0032082879912944 2497.590498318559 0.0001315032871959 0.0029302194560799 2228.248067832571 0.0001273188088065 0.0034277982127002 2692.2952271005843 0.0001607371047849 0.0056812101182921 3534.473341355346 0.0001962857134191 0.0056262782478129 2866.371754626637 0.000303891467026 0.0095463357297031 3141.3635345295024 0.0005254061719692 0.0152213101426301 2897.0558312207595 0.0004238118082864 0.0134335384030099 3169.6942228494104 +r_3282 TAG lipase (1-16:0, 2-18:1, 3-18:0), lipid particle 0.0001235910363962 0.0023306565554652 1885.781221215355 0.0001082855746302 0.002675406210305 2470.6949373821503 0.0001489267054009 0.0031610638746197 2122.563489274756 0.0002307763459172 0.0047290951757419 2049.21139423782 0.0003212891365352 0.0080266048839947 2498.249698247436 0.0001414792218502 0.0036978685099452 2613.7184397709684 0.0007201798032402 0.014677309692312 2038.006290411872 0.0005645036021116 0.0134541066502255 2383.351780200864 0.0006557868575904 0.0166270939692513 2535.4417791085 +r_3283 TAG lipase (1-16:0, 2-18:1, 3-18:1), lipid particle 9.222909649559278e-05 0.0019829582587514 2150.0354379447244 6.60015004566999e-05 0.0022785076523984 3452.205838704044 9.658468745792248e-05 0.002513298282069 2602.170538848584 0.0001837967146795 0.0041842278565473 2276.552039486592 0.0002629870234263 0.0070455043366307 2679.031172275613 0.0001958100450094 0.0053725612211448 2743.761802866052 0.0003085512156306 0.0094854694686181 3074.196110111174 0.0006194451373526 0.0164534534517204 2656.159917896423 0.0004299276490611 0.013110422778851 3049.448624084012 +r_3284 TAG lipase (1-16:1, 2-18:1, 3-16:0), lipid particle 6.758995622302639e-05 0.0016982229869197 2512.537486066904 0.000125696445446 0.0031319025205481 2491.6396875305377 0.0001593892977562 0.0032309765642103 2027.0975590542344 0.0002697993606054 0.0050483090194176 1871.134537935808 0.0005482151900273 0.0101880983384268 1858.4122665258064 0.0003302131628673 0.0071500395251358 2165.2799855249978 0.0006033443470203 0.0133817649028806 2217.9315956081714 0.0007207847987303 0.018023093464026 2500.481904692414 0.0011798567665246 0.0223399659597769 1893.4472889943577 +r_3285 TAG lipase (1-16:1, 2-18:1, 3-16:1), lipid particle 7.069952147329842e-05 0.0017649836239563 2496.4576664396686 0.0001099266821327 0.0029346147419806 2669.61094890304 4.270572876530662e-05 0.0016700581441479 3910.618533934739 8.104769166361957e-05 0.0028456861156755 3511.1254340052733 0.0003042373530764 0.007598531826983 2497.5670311833787 0.0001364037463169 0.0044529773171569 3264.556463728006 0.0002526150737761 0.0085510148929377 3384.99788041802 0.0001850356571336 0.0091667989350865 4954.071597382773 0.0006997464421921 0.0173885294835826 2484.9757619499665 +r_3286 TAG lipase (1-16:1, 2-18:1, 3-18:0), lipid particle 7.034937345547224e-05 0.0017576272406359 2498.426289110314 6.868003939492097e-05 0.0020988337900999 3055.958919929229 9.162361643416348e-05 0.0023952437709231 2614.2209444922664 0.0001062283320979 0.0031997480258735 3012.1418294718364 0.0004523386784906 0.0091493436247828 2022.675499542052 0.0001969860748939 0.0051853246448481 2632.3305582085586 0.0006769812646349 0.0139553673477744 2061.411161105034 0.0011958738617243 0.021594014729799 1805.7100686741385 0.0006457048082659 0.016484688264848 2552.975919308672 +r_3287 TAG lipase (1-16:1, 2-18:1, 3-18:1), lipid particle 4.563813526376697e-05 0.0014001251156847 3067.88414467999 9.851666789901947e-05 0.0027907164523858 2832.735324794344 0.0001017137249222 0.0025288147396088 2486.2079739409955 0.000229032032107 0.0046854515929464 2045.7625729645808 0.0002859361458548 0.0073195707101389 2559.861988856643 0.0003678010174588 0.0073688958176726 2003.5006614677247 0.0004642016467685 0.0112320267936146 2419.6438922187053 0.0003637290505308 0.0125056885702959 3438.188000668466 0.0012046719940409 0.0224222810692011 1861.2768604330668 +r_3288 TAG lipase (1-18:0, 2-18:1, 3-16:0), lipid particle 0.0001069072814954 0.0021134558739422 1976.9054496367569 0.0002726189863323 0.004664154698812 1710.8693571056165 0.0001182302658167 0.002795165794051 2364.17111535876 0.0001477185623756 0.0036266833237882 2455.1303948953764 0.0003713773238331 0.0083624322834194 2251.734757821738 0.0004437622838957 0.0080999487617219 1825.290038308974 0.0005536576700766 0.012668902860155 2288.219516294625 0.000726266541209 0.018148039683299 2498.812578242647 0.0010584907948183 0.0209728325075769 1981.3901651526885 +r_3289 TAG lipase (1-18:0, 2-18:1, 3-16:1), lipid particle 6.777110460971377e-05 0.0016932001864481 2498.410194431792 0.0001455334456289 0.0034173154944806 2348.1306855011035 9.361589095004546e-05 0.0025025377777864 2673.197629579594 9.147903427420604e-05 0.0028837126639703 3152.320842529302 0.0001731071818626 0.0055659252994188 3215.305823554176 0.0002568271969672 0.0063942717109536 2489.717516859523 0.0004255399644064 0.011193780008983 2630.4885428552416 0.0008038290504118 0.0189059632738112 2351.988058172944 0.00053048544931 0.0152419489805891 2873.2077383863534 +r_3290 TAG lipase (1-18:0, 2-18:1, 3-18:0), lipid particle 7.902520246610642e-05 0.001860579490646 2354.412810829579 0.0001776574758643 0.0034166854275244 1923.18697026458 0.0001641329601635 0.0033316467443916 2029.846254567705 0.0001984957516719 0.004434092793215 2233.847704983704 0.0005309304041575 0.0099451691768404 1873.1587226804493 0.0001643340616994 0.0046399213582064 2823.4690424026494 0.0007075416002023 0.0144386261091156 2040.675220366788 0.0005734286982199 0.0152252846044166 2655.1312572391835 0.0008653264292859 0.0193150213351426 2232.1081018040554 +r_3291 TAG lipase (1-18:0, 2-18:1, 3-18:1), lipid particle 7.930139185441928e-05 0.0018437347930642 2324.9715420492857 0.0001466138301688 0.0034098136437845 2325.7107735732025 4.274657538883139e-05 0.001644716266652 3847.59773547093 0.0001548810324606 0.0038276382895935 2471.340892284881 0.0003698964763452 0.0085009444508425 2298.195574836628 0.0002915336425356 0.0066746323907293 2289.4895877796243 0.0004644597808794 0.011359019836241 2445.641216712836 0.0014620837780901 0.0251156216465634 1717.7963412856527 0.0006453637815018 0.0161099972869538 2496.266098085488 +r_3292 TAG lipase (1-18:1, 2-18:1, 3-16:0), lipid particle 0.0001104497718945 0.002177796408674 1971.7527445442463 0.0001896919979048 0.0038610369369622 2035.4242559553795 0.0001351218440244 0.0029404154528224 2176.121465815567 0.0002700347261616 0.0050327184053522 1863.7300753458228 0.0003999934491739 0.0082893409116739 2072.369167243038 0.0004598991719198 0.0085739510359429 1864.3110402115103 0.000333452550035 0.0096163760606262 2883.881397703164 0.0007105333364776 0.0177663564536634 2500.4254609273767 0.00044211218786 0.0137893406303455 3118.968671072047 +r_3293 TAG lipase (1-18:1, 2-18:1, 3-16:1), lipid particle 7.190958461308626e-05 0.0017003259036693 2364.5330630375183 0.0001588523088857 0.0035493876406727 2234.3947441306727 0.0001250206121066 0.0028893989136395 2311.138031523241 0.000143042537428 0.0035938385790683 2512.426473751841 0.0003702066300498 0.0083077674015454 2244.0893077542296 0.0001973620731703 0.0056687287775083 2872.24829292031 0.0003616783782207 0.0104158618570246 2879.868547371895 0.000899645557046 0.0198659874879756 2208.2015892130653 0.00061898516691 0.0164370907499675 2655.490248986046 +r_3294 TAG lipase (1-18:1, 2-18:1, 3-18:0), lipid particle 0.0001212868433111 0.0022899903360879 1888.0781077075724 0.0001172933558537 0.0027395902292729 2335.673840459925 0.0001208521526093 0.0028291193356514 2340.975542898932 0.0001315999178815 0.0035391839400774 2689.3511766961424 0.0002209652379547 0.0063690533569484 2882.377977595039 0.0001437608946164 0.0039445342838739 2743.815899585943 0.0008037301943009 0.0152096089349802 1892.3774474106729 0.0006599039156886 0.0157370745262387 2384.7524089650565 0.0004623799416641 0.0137833656432498 2980.960980625907 +r_3295 TAG lipase (1-18:1, 2-18:1, 3-18:1), lipid particle 7.074809246417318e-05 0.0017287386293983 2443.512707107616 9.783692740318408e-05 0.0027813125186823 2842.804442560485 0.0001381654313849 0.0028425654957093 2057.3637466442365 0.0002220281699392 0.0045786099980397 2062.175263297471 0.0002091287065703 0.0063411880500253 3032.1939794965992 0.0001748313576907 0.0049114631201026 2809.257552521002 0.0005834131215906 0.0129825524511038 2225.2760472214686 0.0005901825261696 0.0158020902755507 2677.49205963587 0.0006190153081165 0.0157909343155596 2550.97638273377 +r_3296 DAG lipase (1-16:0, 2-16:1), lipid particle 2.494465336678242e-05 0.000633994289962 2541.603928665297 4.242627779972144e-05 0.0011277328158369 2658.099824737291 1.0572194787649772e-05 0.0004350310489621 4114.860326546291 8.339559015435114e-05 0.0017496489677324 2098.011375054947 0.0001611850129303 0.0034375015362598 2132.6433976495514 0.000111829986046 0.0026150270481438 2338.395219925955 9.767191600704138e-05 0.0032681468509375 3346.045603018473 0.0002073887645019 0.0059774213145965 2882.2300614742453 0.000104845031252 0.0041442924825725 3952.779099859381 +r_3297 DAG lipase (1-16:1, 2-16:1), lipid particle 3.27049374458448e-05 0.0007308881063721 2234.794387185006 5.872880438467337e-05 0.0013119749200222 2233.954758262706 3.909280720105079e-06 0.0002377240864473 6081.018567551517 5.2238869404133535e-05 0.0013901500607698 2661.141170600912 0.0002409345043091 0.0041264864854499 1712.7005105732906 3.531717384044402e-05 0.0013867759750012 3926.6334879070087 0.0001087650855116 0.0034226783670527 3146.853929227683 0.0003921423583857 0.0081324234546011 2073.844684384196 0.000136017371772 0.0047878444919611 3520.024265714126 +r_3298 DAG lipase (1-18:0, 2-16:1), lipid particle 2.2784227652905063e-05 0.0006058213768607 2658.9506832964894 2.850388940797484e-05 0.000761901661262 2672.974380292327 1.2158908323976846e-05 0.0003219659100817 2647.9836964214232 5.564556744765476e-05 0.0013712027537513 2464.17246987591 0.0001719900917855 0.0035084173492991 2039.895038648162 5.100985775159497e-05 0.0016001921908353 3137.025393459905 0.0001062428722001 0.0033025253480174 3108.467683174252 0.0001725645113671 0.0054343066679459 3149.1449921491344 0.000168404285683 0.0052709531777522 3129.940046580656 +r_3299 DAG lipase (1-18:1, 2-16:1), lipid particle 1.34525580291382e-05 0.0004697162309479 3491.649914689472 1.119072741866158e-05 0.0005594811859667 4999.506868818356 9.459497552810844e-06 0.0003368260697587 3560.7183983962072 5.177739694821359e-05 0.0013508010087532 2608.862338337171 0.0001047994248148 0.0027501776893576 2624.229755282968 0.0001085598405132 0.0025478954661425 2346.9963239594817 7.709203230678415e-05 0.0027732935773308 3597.3802925504087 0.000136863578851 0.0048302560001363 3529.2486435661167 0.0002054968544606 0.0058336001336515 2838.778310724858 +r_3300 DAG lipase (1-16:0, 2-18:1), lipid particle 7.857475877264156e-05 0.0011306516116335 1438.9501530702598 0.0001288908776984 0.0019409743460341 1505.9051351761636 6.565967701953904e-05 0.0012815643433488 1951.8285826588144 0.0001210014980635 0.0020745228995479 1714.460508958665 0.0002090333766597 0.0039149633198535 1872.889096665797 0.000193537156928 0.0033850809189435 1749.0599596866157 0.0004325668023208 0.0068520990978935 1584.055702178156 0.0005979345083451 0.0099317338709606 1661.0069718917878 0.0007062413880094 0.010550961766325 1493.959706335362 +r_3301 DAG lipase (1-16:1, 2-18:1), lipid particle 5.373047524834538e-05 0.0009144189921901 1701.862840340873 0.0001005342341105 0.0017110980410165 1702.0053478849447 7.354220756378958e-05 0.0012280551688303 1669.8644350119523 9.7467570265532e-05 0.0017986814522127 1845.415297942305 0.0001842606935748 0.003604864812975 1956.3938152177625 0.0003131928204378 0.0042408587624428 1354.072790210763 0.0003984428842763 0.0066236464239766 1662.3829124231438 0.0008371148063579 0.0117356232377181 1401.9132320423362 0.0005213919870717 0.0091710630020489 1758.9574119763 +r_3302 DAG lipase (1-18:0, 2-18:1), lipid particle 4.985199152654074e-05 0.000879862971294 1764.950495158579 0.0001074935760678 0.0017109521532366 1591.6785131012384 0.0001325180232502 0.0017721064768774 1337.256950725517 0.0001425007781408 0.0022649422844644 1589.424502809571 0.0001354724182999 0.0030601303237501 2258.858564830012 0.0001766249413254 0.0031466461365794 1781.541221169753 0.0004799875358732 0.0072302392223481 1506.3389529885808 0.0004315101416678 0.008458070324342 1960.1092784633208 0.0008108309332365 0.011396851668268 1405.5768226275975 +r_3303 DAG lipase (1-18:1, 2-18:1), lipid particle 6.638399312035737e-05 0.0010232332446842 1541.3855006117626 0.0001079118620766 0.0017872166216623 1656.1818017676862 0.0001274912621603 0.001713885548791 1344.3160886084802 0.0001680839866423 0.0024435539804779 1453.769647716211 0.0002327286926162 0.0041147895187746 1768.0628342459258 0.0002536719029295 0.0037440791327202 1475.9534223071198 0.0005964901248784 0.0079733066382329 1336.703879189468 0.0004778844335094 0.0090245689815555 1888.4417128386065 0.0008430890336102 0.0114408742866165 1357.0185153073703 +r_3304 DAG lipase (1-16:0, 2-18:1), mitochondrion 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3305 DAG lipase (1-16:1, 2-18:1), mitochondrion 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3306 DAG lipase (1-18:0, 2-18:1), mitochondrion 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3307 DAG lipase (1-18:1, 2-18:1), mitochondrion 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3308 MAG lipase (1-16:0), lipid particle 0.0001035194121394 0.0012963256119272 1252.253645124329 0.0001713171554981 0.0022463283053768 1311.2103681882784 7.623187180718884e-05 0.0013624178180389 1787.2023679084286 0.0002043970882178 0.0027315018833558 1336.3702522238864 0.0003702183895901 0.0052146285612897 1408.5276982223052 0.000305367142974 0.0042898996488815 1404.8334103995264 0.0005302387183279 0.0076534112758056 1443.3897433858267 0.0008053232728471 0.0115855530517267 1438.621413580466 0.0008110864192615 0.0113592929226688 1400.5034054214768 +r_3309 MAG lipase (1-16:1), lipid particle 8.64354126941901e-05 0.0011739779618359 1358.214099109528 0.0001592630384952 0.0021637112141047 1358.5771278435989 7.745148828389466e-05 0.0012517065920401 1616.116900752222 0.0001497064396696 0.002287815821626 1528.201343024542 0.0004251951978839 0.0055578491943812 1307.1288721134583 0.0003485099942783 0.004468422001218 1282.150318377853 0.000507207969788 0.0074498810428351 1468.8020470079894 0.0012292571647437 0.0142549815969375 1159.6419370807348 0.0006574093588437 0.0103448117070537 1573.5723210950698 +r_3310 MAG lipase (1-18:0), lipid particle 7.263621917944577e-05 0.0010727195992653 1476.8384304463634 0.0001359974654758 0.001876057240511 1379.4795615835017 0.0001446769315741 0.0018533316633647 1281.0139413375773 0.0001981463455884 0.0026950426976832 1360.1273794272329 0.0003074625100854 0.0047287541582464 1537.993740092861 0.000227634799077 0.0035576518457369 1562.876967916117 0.0005862304080733 0.008052091220585 1373.5369420785223 0.000604074653035 0.0100576550641107 1664.96889309595 0.0009792352189196 0.0125789938671248 1284.5732694340002 +r_3311 MAG lipase (1-18:1), lipid particle 7.9836551149493e-05 0.0011274673941992 1412.219563553175 0.0001191025894953 0.0018720969485946 1571.8356389456642 0.0001369507597131 0.0017652978023653 1289.0018325295616 0.0002198613835905 0.0028050865236204 1275.8432053007195 0.0003375281174311 0.00494754773044 1465.817949655495 0.0003622317434428 0.0045286816053952 1250.216660293953 0.0006735821571852 0.0085381261869032 1267.570124271499 0.0006147480123605 0.0102345577444522 1664.837874815288 0.0010485858880708 0.0128680632595445 1227.1825709211305 +r_3312 lysoPE (1-16:0) oleoyl-CoA acyltransferase, lipid particle 0.0001099493771581 0.0021587231546054 1963.3791572100704 0.0001293887727624 0.0032224783141912 2490.539360866224 6.23058140048163e-05 0.0019385583176456 3111.360229553812 0.0001959184828082 0.0043902018039912 2240.830850190266 0.0005397171839623 0.010101345027546 1871.5996688091896 0.000385384429543 0.0078463990823759 2035.9927596658447 0.0002980283472741 0.0093134200046101 3125.0114594107604 0.0003360555556987 0.0113956488015383 3391.0014604116595 0.0006097603796601 0.0162058009780137 2657.7326960874752 +r_3313 lysoPE (1-16:1) oleoyl-CoA acyltransferase, lipid particle 5.330800044331012e-05 0.0015369907699613 2883.227202633296 4.888642210880253e-05 0.0019797978545019 4049.790860324452 0.0001354785275207 0.0030273809368147 2234.583584731696 5.74307828437879e-05 0.0023268537041426 4051.579290624866 0.0006230433266942 0.0110082744921833 1766.8553727379303 0.0002507177018782 0.0062765648521322 2503.439049221837 0.0003666229338597 0.0104898024750922 2861.196479079468 0.0003891517331105 0.0130605734392372 3356.164788176912 0.0007707726065123 0.0181095272481551 2349.529173084879 +r_3314 lysoPE (1-18:0) oleoyl-CoA acyltransferase, lipid particle 3.558908159002488e-05 0.0012551742147683 3526.8519407934627 0.0001591859888692 0.0035536312130974 2232.3768808682003 0.0002699871987042 0.0042388358057628 1570.0136251297135 9.717472862894532e-05 0.0030684000875159 3157.611171966791 0.000547963574815 0.01034176226534 1887.30834322891 0.0001990356980264 0.0056775224443336 2852.5146496986 0.0003584414209974 0.0103279944419731 2881.3618730874973 0.0003867284088309 0.0130596305525785 3376.9514352611523 0.0011397437259126 0.0223022211087318 1956.7750715955128 +r_3315 lysoPE (1-18:1) oleoyl-CoA acyltransferase, lipid particle 4.6372051675394855e-05 0.0013761890804651 2967.712298128323 0.0001595455721261 0.0035565391329665 2229.1681840937867 0.0001103810867956 0.0027415937630773 2483.7531887613795 0.0001355213544158 0.0036072550483703 2661.76136146146 0.0007920421084343 0.0123239667811614 1555.973684975242 0.0002669549052887 0.0066138719893458 2477.524053057776 0.0008500490621905 0.0158452251182075 1864.036538946981 0.0007248061727957 0.0178746934548881 2466.134275035402 0.0007156569423535 0.016864357657313 2356.486279844032 +r_3316 PC phospholipase A2 (1-16:0, 2-16:1), lipid particle 8.915514652654762e-06 0.0006264107033612 7026.074520271858 6.286379357309587e-05 0.0022099648707152 3515.4812414327994 2.9451586742854084e-05 0.0013646611935241 4633.574433320786 5.272860932989367e-05 0.002164190734191 4104.3956244909605 0.0003818991992518 0.0085333153817627 2234.441810425369 0.0002193017601242 0.0058194799848648 2653.64034541645 0.0003365589774729 0.0095332613165854 2832.56782753681 0.000876748152334 0.0195686351351179 2231.956244563884 0.000426502283883 0.0130501077322104 3059.797854632416 +r_3317 PC phospholipase A2 (1-16:1, 2-16:1), lipid particle 8.379829735314262e-06 0.0005886005608023 7024.015754423189 4.665370494628572e-05 0.0019043304092393 4081.8417560446906 0.000140515810443 0.0029087079050233 2070.0217974415887 9.881036841291568e-05 0.0031243232611182 3161.938682448918 0.0003419043258503 0.0080847835099259 2364.6332902684862 6.458118996503595e-05 0.0032291929268695 5000.206606006763 0.0003969630486692 0.0101663130577094 2561.0225162747056 0.0002613717073164 0.0106574709902628 4077.5151601858274 0.0006756818402633 0.016868661574896 2496.5391356856626 +r_3318 PC phospholipase A2 (1-18:0, 2-16:1), lipid particle 4.32034128602961e-05 0.001363805038725 3156.7067239226126 0.0001235450941332 0.0030985128165698 2508.001502048733 6.932361841976596e-05 0.0021546244020473 3108.0668481565835 8.119097289466872e-05 0.0028454176726668 3504.598567082406 0.0001180007083665 0.0048171031499181 4082.266298737074 0.0002606149718531 0.0064740668016787 2484.1499917075253 0.0002887895886623 0.0088765880160812 3073.721617595952 0.0011573035602666 0.0219567955347912 1897.237361797526 0.0001765043626164 0.0088058044404178 4989.001013846125 +r_3319 PC phospholipase A2 (1-18:1, 2-16:1), lipid particle 5.874378723524007e-05 0.0015687857859851 2670.556087408828 0.0001106946364813 0.0029589662355999 2673.089076088664 6.622526897703201e-05 0.0020424918946991 3084.1579449191067 0.0001289620955567 0.0034578204894505 2681.26884455736 0.0004329563826258 0.0092412053947864 2134.442582585389 0.0001223552908586 0.0043263757718651 3535.9122940290013 0.0007964815726487 0.0149501853496777 1877.0284038035736 0.0016985568827959 0.0268808173093406 1582.5679776524778 0.0003233366988751 0.011393324413371 3523.6719039334425 +r_3320 PC phospholipase A2 (1-16:0, 2-18:1), lipid particle 5.096955749937144e-05 0.0014674969750992 2879.163655908429 0.000127342686982 0.0031727983351573 2491.543417491623 0.0001150611031556 0.0026176118193526 2274.9754239814256 0.0001021724444693 0.0031750685629028 3107.5585784345394 0.0001772196754603 0.0055007566343063 3103.919821552914 0.0003117509379794 0.0066534328764462 2134.2142286945978 0.0003329393390573 0.0095895343610748 2880.2647317750034 0.0001840098779593 0.0091340186189545 4963.874070375724 0.0011856195722732 0.0224106562259486 1890.206331781441 +r_3321 PC phospholipase A2 (1-16:1, 2-18:1), lipid particle 6.985010184065966e-05 0.0017433997646074 2495.915852183658 8.048349095933755e-05 0.0025441135386548 3161.0377585885267 0.0001268163798516 0.0028560590873783 2252.121603471077 0.0001646504169665 0.003883489235042 2358.627027242995 0.000306744735567 0.0076356747938769 2489.260257314983 0.0002656073941364 0.0063149532470016 2377.5517498421545 0.0003956027289573 0.0106437763762768 2690.521474492609 0.0003673769316509 0.0129380475784784 3521.7365228501294 0.0010079170325751 0.0206138413382993 2045.1922799272515 +r_3322 PC phospholipase A2 (1-18:0, 2-18:1), lipid particle 9.87720267195114e-05 0.0020321161928051 2057.380272833607 6.332267855089934e-05 0.0022117807578619 3492.873025079217 8.094711279964224e-05 0.0021953269361761 2712.0509432003146 9.431461632853718e-05 0.003003529560834 3184.585462736216 9.700297541189026e-05 0.0038553236498922 3974.438550489744 0.0002212402158562 0.0058560963476057 2646.9402612637027 0.0006294775843586 0.0133001637216432 2112.889172248073 0.0009177724544305 0.0204721337437364 2230.6328376828533 0.0004793660760501 0.013904656105364 2900.634149987048 +r_3323 PC phospholipase A2 (1-18:1, 2-18:1), lipid particle 3.542246687021444e-05 0.0012482717510988 3523.954883414639 0.0001097376181058 0.0029240336654859 2664.568190887848 0.0001215563022057 0.002745305566277 2258.464198450388 0.0001144269224944 0.00330680631389 2889.8848643339443 0.0002554743064846 0.006867397364208 2688.097076651012 0.0002856271200854 0.0064777866165049 2267.917211281592 0.0005005962285979 0.0118312547222823 2363.432652183388 0.0005438175659623 0.015695350889855 2886.14268317736 0.0001735793402065 0.0086783165430152 4999.625262250573 +r_3324 PE phospholipase A2 (1-16:0, 2-16:1), lipid particle 3.465864098856522e-05 0.0012158423763969 3508.0497726325875 0.0001919791523343 0.0039044613920093 2033.7944743131443 5.50178635938717e-05 0.0019263324722997 3501.285485237059 0.0001516417458479 0.0037513926550736 2473.852192941008 0.0002009848636548 0.0062335261068688 3101.490327935446 0.0001797198634236 0.0048895110241677 2720.629167539778 0.0003298161103983 0.0095048933585831 2881.8766151546824 0.0005889498966777 0.0157197858972482 2669.1210892339323 0.0006773191442288 0.016887805017622 2493.3305313329347 +r_3325 PE phospholipase A2 (1-16:1, 2-16:1), lipid particle 6.174668300035376e-05 0.0016456733134805 2665.201163066681 3.0788007739414155e-05 0.0015265208356453 4958.166986852871 5.5723698961289314e-05 0.001927625369029 3459.2559448865472 6.102031430563645e-05 0.0024184314383347 3963.321831187909 0.0002384792440741 0.0068609670293961 2876.966109161128 0.0001232883422502 0.0043270791912792 3509.7229083471348 0.0003800667589599 0.0101502035899746 2670.63702643964 0.000523729002039 0.0151344631961275 2889.7508324353525 0.0002346271813811 0.0095569261696245 4073.239133405295 +r_3326 PE phospholipase A2 (1-18:0, 2-16:1), lipid particle 2.5479671820088728e-05 0.0010367555622348 4068.951788529285 9.677597265875669e-05 0.0027916745325714 2884.6773180107207 3.664568997779488e-05 0.0015129376799483 4128.555584204077 0.000129723640263 0.0034756467818253 2679.2701582987584 0.0003169305230595 0.0079121110127702 2496.48122761704 0.0001907718761366 0.0054940020909958 2879.880516066866 0.0003528425263793 0.0101540925901198 2877.797269596297 0.000341080408655 0.0120486630442019 3532.499298834516 0.0005913347022654 0.0156820658151275 2651.977933148011 +r_3327 PE phospholipase A2 (1-18:1, 2-16:1), lipid particle 6.035202973832357e-05 0.0016139231709314 2674.1820911892755 3.207580850332762e-05 0.0016036602458768 4999.594151182518 6.537830209518839e-05 0.0020409579702003 3121.7665567832446 6.924076413548442e-05 0.0024518018523152 3540.9803501269103 7.957949365132876e-05 0.0039754737087484 4995.60065833881 6.415142385755535e-05 0.0028782874636875 4486.708619404344 0.0003021793221861 0.0087576955415049 2898.1782996087927 0.0003504298552316 0.0123929724502305 3536.5058841914083 0.0004226923730441 0.0133748243959991 3164.198185000497 +r_3328 PE phospholipase A2 (1-16:0, 2-18:1), lipid particle 6.869496177613957e-05 0.0017108945997671 2490.567802253823 0.0001861172988333 0.0037944304603394 2038.7306736800283 3.661194140535101e-05 0.0013579792189767 3709.115569540064 0.0001200770815659 0.0034646567130606 2885.360526653288 0.0001250542391604 0.0049214173935142 3935.426281070656 0.0004098957298319 0.0080506905995854 1964.082573606356 0.0003191772215085 0.0090652388398957 2840.1897845495137 0.0006307597441805 0.016789972785264 2661.8649874488765 0.000352807297613 0.0124314268378901 3523.574178311311 +r_3329 PE phospholipase A2 (1-16:1, 2-18:1), lipid particle 9.999461780246326e-05 0.0020133924376296 2013.500808220532 9.48893667010682e-05 0.0027264660032897 2873.3103592934376 0.0001306414105193 0.0029196878599791 2234.886969126514 0.0001638705025332 0.0038675111883012 2360.102110211388 0.0003387258894889 0.0079289795554996 2340.824779429025 0.0002108427281917 0.0056592029073488 2684.087308053547 0.0004747641264218 0.0117825273621803 2481.7644608030064 0.0005496144982789 0.0158418639014012 2882.3591719300143 0.0009189388618993 0.0195668218302555 2129.284399814532 +r_3330 PE phospholipase A2 (1-18:0, 2-18:1), lipid particle 7.096833440895824e-05 0.0017667732121998 2489.5232879761497 9.4743401177651e-05 0.0027310776099056 2882.6045676623603 4.307859660227543e-05 0.0016698905663026 3876.381075548874 0.0001420734600033 0.0035914206075659 2527.861718495656 0.0003830496936105 0.008435485025321 2202.1907773398243 0.0002117043541942 0.0056409447947605 2664.538864223748 0.0002854829970904 0.0089490790583265 3134.715254335002 0.0004577412362544 0.0144461847585864 3155.971892940161 0.0014389485054062 0.0245942248120155 1709.180329915398 +r_3331 PE phospholipase A2 (1-18:1, 2-18:1), lipid particle 5.21501944583332e-05 0.0014146496350762 2712.64498583318 0.0001418410552665 0.0033329471970131 2349.776086162481 0.00015900563175 0.0031498355241441 1980.9584663618857 0.0001295023009303 0.0034650592611803 2675.673896360404 0.0002735954825701 0.0072583963757861 2652.966455293841 0.0002636944079435 0.0063623192867712 2412.7623093670154 0.0009725357556277 0.0165854794123054 1705.3850530770924 0.000603626370936 0.0161798366068417 2680.438991052017 0.000718483946946 0.0170394709096065 2371.586864540865 +r_3332 PA kinase (1-16:0, 2-16:1), Golgi membrane 0.0001328634478881 0.0031291150634854 2355.1361290276245 0.0001075054101575 0.0037997498717883 3534.473163926836 2.270815036102684e-05 0.0016057090503277 7071.069306831553 0.0003353413687317 0.0074917111055758 2234.055146225664 0.0004018428022982 0.0115944000568712 2885.307386510329 0.0002735611649849 0.0086473026659846 3161.012516692122 0.0004021163127038 0.0142127295852295 3534.4822222362523 0.000762289665642 0.0240963005076757 3161.042526711992 0.0010274429261853 0.0274430834587496 2671.0080686076976 +r_3333 PA kinase (1-16:1, 2-16:1), Golgi membrane 8.858640972798523e-05 0.0025559830103343 2885.2992441874544 0.0001060972866295 0.0037504281965386 3534.8954866623203 0.0001134581958413 0.0035864317733364 3161.016043609931 0.0001336208745689 0.0047229054802171 3534.556629308436 0.0002678952795912 0.0094686871703452 3534.473315391421 0.000109441582143 0.0054715324926217 4999.500542190084 0.0003020085037445 0.0123269721721734 4081.6639330792186 0.0009167108726273 0.0264499265609251 2885.307390880939 0.0010274429700441 0.0274430850421359 2671.008108698817 +r_3334 PA kinase (1-18:0, 2-16:1), Golgi membrane 4.429307001154191e-05 0.0018078960027046 4081.667859630216 0.0001343457185821 0.0042466856010951 3161.012978988008 6.806837750257118e-05 0.0027783254559415 4081.668401507889 0.0001677273634953 0.0053018830453263 3161.012571137821 0.0002009215357111 0.008200943719491 4081.664860098844 0.0003828961073696 0.0102271910583777 2671.0094100029914 -2.279999999999997e-11 1.492803299948865e-10 -654.7382894512576 0.000611164711665 0.0216014516660953 3534.4729912896983 0.0005871103632269 0.0207512573303385 3534.47301053978 +r_3335 PA kinase (1-18:1, 2-16:1), Golgi membrane 7.382180923001274e-05 0.0023335170035616 3161.013022982 8.057303721415915e-05 0.0032887240391117 4081.668201696876 0.0001362377545786 0.0039308783921706 2885.307677250274 6.709097198499718e-05 0.003354213940769 4999.501187013846 0.0002009213684933 0.0082009409823667 4081.666894796947 0.0003830456851445 0.0102311816499205 2671.008197380106 0.0007044132291926 0.0188149405978202 2671.0089785485115 0.0010695384617711 0.0285674589717796 2671.0081023614284 0.0004403326538225 0.0179729099895375 4081.666402323783 +r_3336 PA kinase (1-16:0, 2-18:1), Golgi membrane 5.903599516953332e-05 0.0020866124562867 3534.4749424392376 0.0001612003116901 0.004651126270045 2885.308484380803 9.083317802118743e-05 0.0032104511106212 3534.4476330800703 0.0001338053494739 0.0047293377741781 3534.4908053152303 0.0005347966689493 0.0133607005186124 2498.276689879456 -1.939999999999998e-11 1.3794000684753668e-10 -711.0309631316335 9.843179508220544e-05 0.0069601813833429 7071.070254819754 0.0003055823384193 0.0152775897975464 4999.500257957539 0.0005870837223702 0.0207503158509684 3534.4730334528576 +r_3337 PA kinase (1-16:1, 2-18:1), Golgi membrane 7.3821809602235e-05 0.0023335171039249 3161.01314299709 0.0001343796636057 0.0042477459231594 3161.003539658431 0.000113540691435 0.0035890357264733 3161.012744515125 0.0001341390541806 0.004741109927403 3534.4739504556574 0.000598897658518 0.014106892775587 2355.4763614359467 0.0002188832564492 0.0077363671046393 3534.471859628684 0.0004026466916204 0.0142314395577125 3534.4732376761103 0.0003055823409932 0.015277589786189 4999.50021213002 0.001027443355183 0.0274430943639025 2671.008014744951 +r_3338 PA kinase (1-18:0, 2-18:1), Golgi membrane 4.4284414896378136e-05 0.0018075429623265 4081.6683850426616 0.0001343817557052 0.0042478246170348 3161.012888052471 4.541634773701847e-05 0.0022705861662098 4999.490886756337 0.0001340511847948 0.0047380102949918 3534.478492110093 0.00033486916312 0.010585256477908 3161.012611397734 0.0003282834897258 0.009471985168207 2885.30659160419 0.0007046858951823 0.0188222179083733 2671.00818067366 0.0012222879527943 0.0305357976961684 2498.249093133865 0.0010258844730408 0.0274016243262881 2671.024374222685 +r_3339 PA kinase (1-18:1, 2-18:1), Golgi membrane 0.0001328563745162 0.0031289491032634 2355.136601202239 5.375313306779238e-05 0.0026873657319442 4999.458782346613 0.0001362487806556 0.0039311968362779 2885.30790320498 0.0001677281814843 0.0053018839147247 3160.997673618895 0.0006027644975779 0.0141959222428664 2355.135761961624 0.0004924903470376 0.0115987477850828 2355.121852611018 0.0002013387718376 0.0100659335568563 4999.500823902686 0.0016807035740633 0.0357968618384592 2129.8736071534404 0.0008806655009916 0.0254099072947357 2885.30744830188 +r_3340 PA kinase (1-16:0, 2-16:1), vacuolar membrane 0.0001033499904713 0.0027604892815831 2671.010678368774 8.062936802694021e-05 0.0032910080880627 4081.649364984614 0.0001361775710614 0.003929143571275 2885.308895325911 0.0002012728809327 0.0058073436893796 2885.308573348983 0.0004688165933783 0.0125221312955649 2671.008550556636 0.0002188831354828 0.007736367101971 3534.473811746193 0.0001006693161646 0.007118402281093 7071.074436874065 0.0007638691155899 0.024146000838189 3161.0128417798487 0.0005871102220005 0.0207512580408626 3534.4739817598097 +r_3341 PA kinase (1-16:1, 2-16:1), vacuolar membrane 1.476427989678413e-05 0.0010439988031625 7071.112241579484 0.0002150108278325 0.0053715079458067 2498.2499718529984 0.0001135407624616 0.003589035544059 3161.010606452748 -9.520000000000091e-11 2.9381835518763216e-10 -308.6327260374258 0.0003348689149263 0.0105852504898463 3161.013166054237 0.0003830457973034 0.0102311828659967 2671.0077327624285 0.000401705342901 0.0141982881319227 3534.5031832002883 0.0012223296612402 0.0305368422908866 2498.249306975081 0.0013209978792439 0.0311112990384483 2355.136183583769 +r_3342 PA kinase (1-18:0, 2-16:1), vacuolar membrane 2.9528619683617096e-05 0.001476288140613 4999.516253826437 0.0001611715591436 0.0046502914059474 2885.305218027629 0.0001589568988106 0.0042457540497409 2671.0096142460425 0.0001006363701131 0.0041076444403316 4081.669912888056 0.0001339475943038 0.0066967145911764 4999.50344459894 0.0003283248643933 0.0094731825959673 2885.307700795145 0.0007014306844826 0.0187364851146783 2671.1812769492903 0.0010695383111831 0.0285674579546498 2671.008383331941 0.0005871100823474 0.0207512534055326 3534.474032972057 +r_3343 PA kinase (1-18:1, 2-16:1), vacuolar membrane 8.823953055618485e-05 0.0025460684861032 2885.405747350513 0.0001612580400133 0.0046527934361851 2885.309430648412 0.0001362489424712 0.0039311977576606 2885.305152728386 0.0002011579071827 0.0058040280730531 2885.3094339365066 0.0002009213872961 0.0082009444902783 4081.668258734655 0.0004089657859164 0.0103924900566454 2541.1636901009056 0.0002515867246486 0.010671614659369 4241.724071200601 0.0004582955485223 0.0187061002201395 4081.667448102696 0.0005871104007004 0.0207512567509754 3534.4726862647435 +r_3344 PA kinase (1-16:0, 2-18:1), vacuolar membrane 7.371673838456715e-05 0.0023302076271466 3161.0292020657816 0.000187894096744 0.0050186934613635 2671.022426106241 0.0001323235900454 0.0038226434671693 2888.860154002477 0.0001670497733042 0.005280587253206 3161.08615339948 0.0001339475012455 0.0066967102463196 4999.50367423711 0.0002736040071101 0.0086486597357207 3161.013549131844 0.0008053554041209 0.0201197862495241 2498.249362526484 0.0007639560212558 0.0241487475626154 3161.0127927151966 0.0003119840860495 0.0147336636902591 4722.56898639326 +r_3345 PA kinase (1-16:1, 2-18:1), vacuolar membrane 0.0001032639269217 0.0027581893588724 2671.009558801405 0.0001612580030878 0.0046527917511159 2885.3090463862736 0.0001361774212794 0.003929142554268 2885.311322061584 0.0002012728595669 0.0058073433126789 2885.3086924749205 0.000334856298211 0.0105848375264422 3161.0089411456647 0.000109442021912 0.0054715346818105 4999.482453099482 0.000503347061274 0.0159108655518888 3161.0129026313634 0.00076395605204 0.0241487486179746 3161.0128034836616 0.0007338877585997 0.0231982880527093 3161.013081478886 +r_3346 PA kinase (1-18:0, 2-18:1), vacuolar membrane 0.0001033504414883 0.0027605015104072 2671.010854578003 0.0001612174206624 0.0046515899924618 2885.2899229791733 6.812434404430621e-05 0.0027806125940895 4081.672466866111 0.0002683634952742 0.0067043908178663 2498.249924422402 0.0002007321557758 0.0081932279237389 4081.671863718254 0.0001641608723663 0.0067005038287726 4081.669238342468 0.0004946279533655 0.0156449766121089 3162.9786601542287 0.0004583734380563 0.0187092791677399 4081.667394837521 0.0002935549392256 0.0146762885574702 4999.503192207727 +r_3347 PA kinase (1-18:1, 2-18:1), vacuolar membrane 8.85861044019375e-05 0.002555984300248 2885.310644941492 0.0001075052960691 0.0037997499188368 3534.4769585995914 0.0001135406285425 0.0035890366463112 3161.0153056056783 0.0001677273111686 0.0053018840032995 3161.014128444113 0.0005357905038036 0.0133853826452823 2498.2493251106584 0.0003283247120702 0.0094731803404891 2885.30835244072 0.0006038179545281 0.017422011524628 2885.308625551429 0.0007639558738574 0.0241487424287012 3161.012730587207 0.000733698558565 0.0231923105426077 3161.0135077772698 +r_3348 inositolphosphotransferase (PI (1-16:0, 2-16:1) MIPC-A (C24)) -2.370760330236385e-10 2.526178222551949e-09 -1065.556138397198 -6.031768843640109e-11 2.450361992525036e-09 -4062.4268867808096 -7.358837817029902e-10 4.0281198861945275e-09 -547.3853326231227 -5.428816408653836e-11 2.2352599335730008e-09 -4117.398278582182 -1.806234525592684e-10 2.833093539667849e-09 -1568.5081308797485 -1.3622478250450048e-10 2.6906223937688752e-09 -1975.1342922349568 -1.0893943201051107e-10 2.423179834904996e-09 -2224.3367623499216 -1.0464687668967624e-10 2.796954090453056e-09 -2672.754485303224 -1.213708895702092e-11 2.09155830903738e-09 -17232.7838779453 +r_3349 inositolphosphotransferase (PI (1-16:1, 2-16:1) MIPC-A (C24)) -3.0474920510481845e-10 2.752517694571217e-09 -903.2075058651882 -1.1372259541448512e-11 2.372156397431374e-09 -20859.147549223333 -3.042318140521846e-11 2.532939498750446e-09 -8325.689102047603 -2.4125909292032877e-10 2.719018205809908e-09 -1127.01170053218 -5.833847877257018e-11 2.4381150807885987e-09 -4179.257210825596 -2.3419924298841325e-10 2.227663423578269e-09 -951.1830162868976 -1.8904736080243208e-10 2.962535962129528e-09 -1567.086654664059 -5.735650945968418e-12 2.1478564222417482e-09 -37447.4744449272 2.091886764949534e-11 2.383060526155324e-09 11391.919324145703 +r_3350 inositolphosphotransferase (PI (1-18:0, 2-16:1) MIPC-A (C24)) -1.4980042442193842e-10 2.617204941191698e-09 -1747.1278544711563 -1.8069062295207166e-10 2.9279695225441194e-09 -1620.4324688839915 -1.1234905851507828e-10 2.4962093257325576e-09 -2221.833772997344 -1.1600926041196188e-10 2.583046666707232e-09 -2226.5866169084634 -1.5929668535412287e-10 2.5362958613021314e-09 -1592.1837015402075 -7.931987807704471e-11 2.264678632287754e-09 -2855.121171628674 -1.1896249703993104e-10 2.754425401962716e-09 -2315.37288683354 -1.4737321835183746e-10 2.3959454819303582e-09 -1625.7672246868492 -1.7339797592536172e-10 2.5362936081283884e-09 -1462.7008156197412 +r_3351 inositolphosphotransferase (PI (1-18:1, 2-16:1) MIPC-A (C24)) 7.848897636293301e-11 2.3125687920556404e-09 2946.361258888539 -4.433656722537762e-11 2.609435785262415e-09 -5885.516061714428 1.983529872411597e-11 2.7127158671160262e-09 13676.203745890038 -3.592843063468418e-11 2.3807531864222197e-09 -6626.376783972066 1.1198126626828007e-11 2.310099336322537e-09 20629.33750711567 -9.973678951585484e-11 3.203031649410908e-09 -3211.4846136106403 1.8091187160877988e-11 2.808815663995475e-09 15525.87809201107 -7.838142234161807e-11 2.3156651137615406e-09 -2954.3545454800906 -3.5231788843556716e-11 2.2791067608345347e-09 -6468.89310944353 +r_3352 inositolphosphotransferase (PI (1-16:0, 2-18:1) MIPC-A (C24)) 9.265056709149275e-11 2.912849537229485e-09 3143.9090214666858 5.4811293465747966e-11 2.777920767586106e-09 5068.154009760876 7.928114556645843e-11 2.497079069174343e-09 3149.6505901029577 1.34715082907599e-10 2.0513642107024056e-09 1522.7427890234349 -9.180478172662748e-12 2.572264250945104e-09 -28018.84828401083 1.5728741167975768e-11 2.953871436255461e-09 18780.088022998563 5.356427261487606e-11 2.959955336757767e-09 5525.988111590108 4.813301112024346e-11 2.2211388920610606e-09 4614.585375746227 7.439812592255254e-11 2.394989040640665e-09 3219.152379098658 +r_3353 inositolphosphotransferase (PI (1-16:1, 2-18:1) MIPC-A (C24)) 1.0301940303646595e-10 2.5348600980378557e-09 2460.565702502263 -7.628689082390078e-11 2.460365911304508e-09 -3225.149019356379 -3.6935326014317566e-11 2.5037066366237798e-09 -6778.62335817273 3.1215527811670426e-11 2.384925490092132e-09 7640.189537978883 -5.553159577616415e-11 2.7771530648327767e-09 -5001.032342068613 3.87624595036762e-11 2.8069493892916047e-09 7241.411987867787 6.012615233640703e-11 2.253928434275714e-09 3748.665674904557 -1.933683806874996e-11 2.853336179920145e-09 -14755.96046145408 -1.2420032487736388e-10 2.34346300896165e-09 -1886.841287472958 +r_3354 inositolphosphotransferase (PI (1-18:0, 2-18:1) MIPC-A (C24)) 9.678782767818447e-11 2.66789604388613e-09 2756.4375685305945 8.656724397714477e-11 2.4785778138540486e-09 2863.182076708409 1.6041520830890388e-10 2.086949235830166e-09 1300.967194962854 1.3587864934882466e-10 2.2782759655656644e-09 1676.6990078896986 1.3566121553166983e-10 2.3570667593428514e-09 1737.4654576883097 -1.955580819309793e-11 2.923856537721309e-09 -14951.345957428965 1.1956436910999425e-10 2.465501330101978e-09 2062.070287707385 1.1384296946788164e-10 1.983148878672132e-09 1742.003821528597 8.116229227638759e-11 2.4113254406932044e-09 2970.992283561621 +r_3355 inositolphosphotransferase (PI (1-18:1, 2-18:1) MIPC-A (C24)) 1.1929020094473662e-10 2.3363759311435044e-09 1958.5648382182487 6.403776557826472e-14 2.742263550153577e-09 4282259.890536123 2.400186462469882e-11 2.8841898210333915e-09 12016.523991496277 1.2170000523865683e-10 2.294570315452289e-09 1885.4315667058336 1.1969701769616848e-11 2.698939835723901e-09 22548.09591475974 1.5063541867138242e-10 2.230597495733309e-09 1480.7921771701333 3.8331820969622014e-11 2.448466309945217e-09 6387.555425257851 1.7738220543641586e-11 2.553646896873451e-09 14396.29691484937 7.494019231347488e-11 2.3772386901501007e-09 3172.181197782506 +r_3356 inositolphosphotransferase (PI (1-16:0, 2-16:1) MIPC-A (C26)) -1.2785356295467216e-10 2.3040732567375467e-09 -1802.11892691204 1.3817346419481984e-11 2.1636366509794562e-09 15658.843494933317 -1.0085234291574957e-11 2.3368288924043724e-09 -23170.794300302205 -2.5215915801735447e-11 2.2490370559844427e-09 -8919.117091236703 -6.37870844507662e-12 2.405994452913393e-09 -37719.14759280854 -1.0146880587248903e-10 2.3189087054829264e-09 -2285.341475681686 -1.0499533349705354e-10 2.578863584834095e-09 -2456.1697162535943 -6.737719362732869e-11 2.198860126109058e-09 -3263.5080325120343 4.2056555634422175e-11 2.091833359328665e-09 4973.858005662631 +r_3357 inositolphosphotransferase (PI (1-16:1, 2-16:1) MIPC-A (C26)) -2.9251735031898884e-10 2.3680196258091383e-09 -809.5313400134467 2.9572208089779485e-11 2.4030015906840407e-09 8125.878133241417 -1.1590345136992448e-10 2.6969659171603196e-09 -2326.907339931164 -2.7323125888828267e-10 2.8839677376685437e-09 -1055.5043187235487 -9.235619334844271e-13 2.4654656381418684e-09 -266951.846839348 -2.2389745413266686e-10 2.6648951654767067e-09 -1190.2302220451625 -2.2919742694016693e-11 2.255224207651205e-09 -9839.657616400478 6.438510304449506e-11 2.086969827856402e-09 3241.38617346647 -4.0024285291570205e-11 2.4182825489339508e-09 -6042.038055938207 +r_3358 inositolphosphotransferase (PI (1-18:0, 2-16:1) MIPC-A (C26)) -7.912050649597211e-11 2.5337895106912077e-09 -3202.443491460964 -5.265429955564961e-11 2.739713858100784e-09 -5203.210148499304 -1.9068928472773382e-10 2.5184440321246703e-09 -1320.7055843334376 1.4883861075479298e-11 2.3742498725635433e-09 15951.841128610416 -6.925507740298691e-11 2.107022292734283e-09 -3042.408400576575 -2.3289767304020142e-11 2.904708229990026e-09 -12472.036289897287 -2.2632294739362323e-10 2.653283098583589e-09 -1172.343825113311 -1.4437290103516503e-10 2.2681006272084393e-09 -1571.001629077188 -1.4516140124202129e-11 1.910808870238437e-09 -13163.339936713815 +r_3359 inositolphosphotransferase (PI (1-18:1, 2-16:1) MIPC-A (C26)) -1.3268659942151182e-11 2.4827549957844484e-09 -18711.422303448777 7.953165049921095e-11 2.9053902389009663e-09 3653.1245367902825 -2.5732476577044817e-11 2.6557684600357966e-09 -10320.68736984659 3.35062998228255e-11 2.371174547773424e-09 7076.802154555152 1.2498464843256238e-10 2.0044867371832117e-09 1603.786354821622 1.1590214166526215e-10 2.104484564043753e-09 1815.7426030329368 -6.990702160683324e-12 2.715198424955747e-09 -38840.138837932456 -1.098562383000616e-10 2.431070914403741e-09 -2212.95663498281 1.0587757925197103e-10 2.108215167561395e-09 1991.1818748180792 +r_3360 inositolphosphotransferase (PI (1-16:0, 2-18:1) MIPC-A (C26)) 1.413270789939194e-10 2.1874326965958554e-09 1547.7803066247268 1.4336998557138915e-10 2.5716988849154684e-09 1793.7498386891623 1.0803527112053304e-10 2.313933709020201e-09 2141.831723121781 -1.9783268564022872e-10 3.214889480260514e-09 -1625.0547627438038 1.5774739487451262e-10 2.327657307904819e-09 1475.5599037032976 4.1200508033188896e-11 2.817678706855508e-09 6838.941657189614 3.5284545501521344e-11 2.65481242419674e-09 7524.009127685304 8.067362032585423e-11 2.028485564804641e-09 2514.4347763385967 3.6887530146166236e-11 2.2019668631791203e-09 5969.407153186624 +r_3361 inositolphosphotransferase (PI (1-16:1, 2-18:1) MIPC-A (C26)) 6.703204422047117e-11 2.600251543417593e-09 3879.117179934508 2.66256488920019e-11 2.8168417378607846e-09 10579.429441462133 3.780256265492755e-12 2.67764907813729e-09 70832.47510438978 -1.5256509548021213e-12 2.460262735358227e-09 -161259.869278378 2.5288393861348423e-11 2.494154383918453e-09 9862.842209724506 1.1215424063076359e-10 2.4044873103115804e-09 2143.9111858709653 1.7019970324508032e-11 2.6751321415165406e-09 15717.607554605804 1.0552651002369955e-11 2.25557774032359e-09 21374.512810259937 9.163192200303995e-11 1.868420535958931e-09 2039.0498148635847 +r_3362 inositolphosphotransferase (PI (1-18:0, 2-18:1) MIPC-A (C26)) 2.1007630105015123e-10 2.113434593895898e-09 1006.0318957117212 1.9447015244467272e-10 2.428869084760547e-09 1248.9675429506165 1.4539278333290234e-10 2.244157663718415e-09 1543.5137922767606 1.6575837998275758e-10 2.2374558007831123e-09 1349.8296743825897 1.7798889671631738e-10 2.2550010187800767e-09 1266.933533710334 1.4089199509851627e-10 2.218748455870902e-09 1574.7867395301491 1.8691798766703947e-10 2.323456779682063e-09 1243.0354128468794 1.9160768781712656e-10 2.129664635951797e-09 1111.4713925176022 1.69243488911127e-10 2.010780534312388e-09 1188.0991979362273 +r_3363 inositolphosphotransferase (PI (1-18:1, 2-18:1) MIPC-A (C26)) 7.668929654834137e-11 2.6058558240758166e-09 3397.939401404218 9.803197546815444e-11 2.5537396151166428e-09 2605.0067877559213 8.014940612437737e-11 2.358524127786217e-09 2942.6595178087973 7.564874611360816e-11 2.4904430125720204e-09 3292.114067339477 1.2228191447783742e-10 2.426745017109737e-09 1984.5494139279 1.3740075146138468e-10 2.3768790068361083e-09 1729.887923869259 5.3205411806709886e-11 2.3842221600266637e-09 4481.164751977321 3.8437347690887593e-11 2.496749139524342e-09 6495.633256496131 1.4882026285643046e-10 2.2520865647248464e-09 1513.2929625970855 +r_3364 inositolphosphotransferase (PI (1-16:0, 2-16:1) MIPC-B' (C24)) -4.3951864491185327e-10 2.953915366451524e-09 -672.0796490997419 3.275708555320601e-11 2.372446197456933e-09 7242.543582222738 1.9078527530101368e-11 2.0885836967923038e-09 10947.300275123516 -1.169242950647677e-10 2.184107901220402e-09 -1867.967559702252 -1.0653415670763168e-10 2.351492450527831e-09 -2207.266216957232 -1.1025069613057666e-10 2.123639223725533e-09 -1926.1912153465016 -9.095653845115367e-11 2.110492680039823e-09 -2320.330914058718 -1.0816769189578876e-10 2.2498903838960443e-09 -2080.0022118098263 3.852226071031077e-11 1.94366911449651e-09 5045.573854330603 +r_3365 inositolphosphotransferase (PI (1-16:1, 2-16:1) MIPC-B' (C24)) -2.071467588534456e-10 2.453055486560639e-09 -1184.2113775461737 3.1925817468030005e-11 2.522012191536184e-09 7899.600986135084 -2.2347637110191001e-10 2.868138814028365e-09 -1283.4192715257727 -1.8524179933220846e-10 2.448157089798236e-09 -1321.6007934622608 -7.305697730773043e-11 2.1814671860189915e-09 -2985.980622809264 -2.2000507568272472e-10 2.172059774219354e-09 -987.2771196205222 -4.0235841917880506e-11 2.177871368524486e-09 -5412.764502279886 -2.7321005194415216e-10 2.6555828215014637e-09 -971.9930883232292 9.998902254329336e-12 2.498907705291538e-09 24991.82051919308 +r_3366 inositolphosphotransferase (PI (1-18:0, 2-16:1) MIPC-B' (C24)) -7.459883951580463e-11 2.245440089061874e-09 -3010.020133873734 -1.1649378253284626e-10 2.533766997998694e-09 -2175.0233728433363 -2.1030799946710006e-10 2.615964887071334e-09 -1243.8732210376843 -2.3092626886092608e-10 2.406445244800872e-09 -1042.083803055831 -7.3331017142102e-11 2.3285361290975404e-09 -3175.3768321326666 -9.5938003294225e-11 2.0534939830105123e-09 -2140.4385254014583 -1.6411774298122349e-10 2.6472813115509713e-09 -1613.0378492067389 -1.9620759078548567e-10 3.052844028569813e-09 -1555.9255461770058 -9.983774410838056e-11 2.689531713710385e-09 -2693.902729603664 +r_3367 inositolphosphotransferase (PI (1-18:1, 2-16:1) MIPC-B' (C24)) 8.045798557194766e-11 2.283811618955357e-09 2838.51453988133 -2.353675744017839e-10 3.240406614198733e-09 -1376.7430039735218 -1.5369627454546782e-10 2.723171286918213e-09 -1771.7874392021265 8.643150523227766e-12 2.3684003097314795e-09 27402.048632227285 1.7583563079760168e-11 2.265067355091828e-09 12881.731335209692 1.2780695574528454e-10 2.240359458857849e-09 1752.9245147837016 -1.3455229955599248e-10 2.629737736792945e-09 -1954.435372320492 4.5576959976264895e-11 2.3196527791664107e-09 5089.529403396839 -8.182789912092631e-11 2.4176371417303427e-09 -2954.5389380674774 +r_3368 inositolphosphotransferase (PI (1-16:0, 2-18:1) MIPC-B' (C24)) 6.257767128315748e-11 2.974520854733886e-09 4753.326216430279 3.984498892911685e-11 2.711375885376021e-09 6804.810236487919 1.1952985497287998e-10 2.1951168385015447e-09 1836.4590494982133 1.0126448768280662e-10 2.2111235171611998e-09 2183.513260924362 7.224956717231051e-11 2.145535059491674e-09 2969.6164883240235 1.6566533757374103e-10 2.102471660077339e-09 1269.107763198494 5.8108955659122125e-11 2.115186907692742e-09 3640.036004262096 1.1364861796777619e-10 2.007435846794488e-09 1766.3530649916695 6.218919352956263e-11 2.212617611976759e-09 3557.881179026636 +r_3369 inositolphosphotransferase (PI (1-16:1, 2-18:1) MIPC-B' (C24)) 6.394854444419551e-11 2.8844996049779704e-09 4510.657169836164 -7.450879954188979e-11 2.590526446992958e-09 -3476.80604562221 1.4970343441300413e-11 2.170379434564308e-09 14497.8600061815 4.853906595127504e-11 2.1558023095483483e-09 4441.375760531541 -3.2918878626358524e-11 2.293411339365495e-09 -6966.857423658212 2.7976421924859704e-11 2.2186850854884736e-09 7930.553419045205 1.1294738317121043e-11 1.933538156084329e-09 17118.92831685521 3.455853303393453e-11 2.357972170076191e-09 6823.125761040827 -2.928674605399908e-11 2.595915739752366e-09 -8863.790244795378 +r_3370 inositolphosphotransferase (PI (1-18:0, 2-18:1) MIPC-B' (C24)) 1.5258302426902428e-10 2.097711110457472e-09 1374.799798671526 3.056022667169195e-11 2.340809559809833e-09 7659.660332225656 9.60757635072769e-11 2.3496028058758236e-09 2445.572868851427 1.5129736098568347e-10 2.3122538294141246e-09 1528.284310017094 1.2491749140424076e-10 2.113493975166874e-09 1691.9119583721676 1.577007507503513e-10 2.1562277263093994e-09 1367.2907174188556 1.1418303713113903e-10 1.8781133308916382e-09 1644.8269183229272 1.8695164205487208e-10 2.1511442785093524e-09 1150.6420884380211 9.677171356135512e-11 2.4214574945643915e-09 2502.2368680380355 +r_3371 inositolphosphotransferase (PI (1-18:1, 2-18:1) MIPC-B' (C24)) 8.762111560692658e-11 2.4777589087113637e-09 2827.81027329843 2.009640640792439e-11 2.659068510958054e-09 13231.562185712632 8.818905183111186e-11 2.296815908512423e-09 2604.42295366888 5.746738081594508e-11 2.2587951651080587e-09 3930.569190794452 6.557139159335976e-11 2.2153490187764472e-09 3378.52982061889 1.5559762145286614e-11 2.3342949037140084e-09 15002.124594951583 1.5792544861694012e-10 2.087625369793738e-09 1321.9056131082634 9.940910965547192e-11 1.8565713226800083e-09 1867.606831118836 1.7924089882920197e-11 2.20785137296404e-09 12317.78788984926 +r_3372 inositolphosphotransferase (PI (1-16:0, 2-16:1) MIPC-B' (C26)) -1.5285367637229127e-10 2.2856378848622086e-09 -1495.3110315091776 -4.7091825142538505e-11 2.597156162199544e-09 -5515.089199321578 -4.599546859320208e-10 3.1733838363453504e-09 -689.9340159813835 -8.303115928849635e-11 2.282294946662164e-09 -2748.7210418587606 -2.2943179450953182e-11 2.494473527491915e-09 -10872.39688302347 -1.8062636554852527e-10 2.5422467731572072e-09 -1407.461621362376 -8.131675722982517e-11 2.703620374204597e-09 -3324.8010204875336 -2.4690614139240608e-11 2.228452475120803e-09 -9025.50443886748 2.8574744995014008e-11 2.4205553662193867e-09 8470.960516504165 +r_3373 inositolphosphotransferase (PI (1-16:1, 2-16:1) MIPC-B' (C26)) -2.1473971200089838e-10 2.429858694574314e-09 -1131.5367204013703 -2.8761001324902268e-11 2.591147915508179e-09 -9009.240972652344 -6.7031768938642815e-12 2.0353280862044696e-09 -30363.633817682723 -1.2040767942493239e-10 2.2548552579199627e-09 -1872.683925717331 6.635740894592533e-11 2.4910445840413702e-09 3753.9810905988256 -1.6822209741765838e-10 2.405158191617687e-09 -1429.7516369958275 3.534675821641287e-12 2.999489097113405e-09 84858.95874096385 -7.704106146893374e-11 2.354279842907773e-09 -3055.8766948676057 4.472340662571215e-11 2.0273619898083488e-09 4533.111725533869 +r_3374 inositolphosphotransferase (PI (1-18:0, 2-16:1) MIPC-B' (C26)) -1.2658415049583123e-10 2.4738313314971446e-09 -1954.2978499339176 -1.2855829190533542e-10 2.569629682748923e-09 -1998.8050904107247 -2.9337451683324367e-11 2.2751685532126848e-09 -7755.167619094565 -1.3491583127055988e-10 2.467899605515681e-09 -1829.2142458556705 -5.868684993724367e-11 2.6433476801466082e-09 -4504.156694341666 -1.1334594225520564e-10 2.5615599353286515e-09 -2259.9485119292003 -2.7831953373532457e-10 2.6433137280913448e-09 -949.7406425684352 -1.0361766200316412e-10 2.006765563764893e-09 -1936.7022233175007 -1.3120725052400848e-10 2.36069488999968e-09 -1799.2106995395936 +r_3375 inositolphosphotransferase (PI (1-18:1, 2-16:1) MIPC-B' (C26)) -4.1674295064001976e-11 2.7961619086441286e-09 -6709.560184161188 9.602806258013132e-11 2.1175885186451724e-09 2205.1767595312413 1.0056359820143979e-10 2.096630615691973e-09 2084.880267999356 -9.14717135765707e-12 2.4367711224876353e-09 -26639.613791074567 4.474128975598551e-11 2.46890148421181e-09 5518.172358635502 1.4273185571300296e-10 2.2747273523246915e-09 1593.706843480395 7.714466552667854e-11 2.2731611552580964e-09 2946.62131171206 8.233304140251986e-11 2.0746471496974603e-09 2519.82328644301 -5.5254917362486446e-11 2.1656550639968743e-09 -3919.388838806184 +r_3376 inositolphosphotransferase (PI (1-16:0, 2-18:1) MIPC-B' (C26)) 1.4023455896655886e-10 1.979760778831394e-09 1411.749566883509 8.077076429815309e-11 2.358588056844652e-09 2920.1011991644405 1.3283797600995147e-10 2.3520749367703e-09 1770.6344280600129 1.6127405990375148e-10 1.954587024239003e-09 1211.9661558749765 6.580430781905489e-11 2.267948731293383e-09 3446.5049575928456 5.5647130044590535e-11 2.495264772518901e-09 4484.085289788392 -3.2023191482338066e-11 2.541226449070915e-09 -7935.581469050304 3.366985104553011e-11 2.473476198242943e-09 7346.264154534515 1.1963407419756515e-10 2.1473075275450484e-09 1794.8962634165237 +r_3377 inositolphosphotransferase (PI (1-16:1, 2-18:1) MIPC-B' (C26)) 1.0567086643207188e-10 2.2311193870418016e-09 2111.385533567122 7.341916078542169e-12 2.4980490346196475e-09 34024.48363473622 2.3466872834293727e-11 2.3061100909255566e-09 9827.087346531667 1.4060772642478662e-10 2.250901796856689e-09 1600.837915589748 7.827829326913416e-12 2.5287241166547994e-09 32304.282720633848 4.4388368557565024e-11 2.6487100639776828e-09 5967.126411827245 1.7712819490848395e-11 2.362177083671779e-09 13335.974461277803 2.453230443341941e-11 2.4801425742041287e-09 10109.700786304962 7.238617472519808e-11 2.7622700701388004e-09 3816.0188470039934 +r_3378 inositolphosphotransferase (PI (1-18:0, 2-18:1) MIPC-B' (C26)) 1.8151350337577315e-10 1.8878433301809864e-09 1040.0566872827817 1.0944404448466747e-10 2.402577003771144e-09 2195.256046214312 1.94677523621701e-10 2.220858268612716e-09 1140.7882262403884 1.8066106439933927e-10 2.050423044767e-09 1134.9556981656417 2.0125043873138864e-10 2.2205628581779423e-09 1103.3828657346453 1.7614908615274995e-10 2.244815672883004e-09 1274.3839448229571 1.6396222607210412e-10 2.168140668979607e-09 1322.3415666643514 1.4411667714403391e-10 2.041137715784256e-09 1416.3091713142194 5.730395457343082e-11 2.100238515960295e-09 3665.084777472021 +r_3379 inositolphosphotransferase (PI (1-18:1, 2-18:1) MIPC-B' (C26)) 1.8544454772912027e-10 2.591229621072973e-09 1397.3069862684747 4.870095767978584e-11 2.355321504903157e-09 4836.294021956725 1.1960128614702302e-10 2.184352922847241e-09 1826.3624022922868 1.5630443613024312e-10 2.0822575031763064e-09 1332.180681961728 8.251786847600801e-11 2.597160815798885e-09 3147.3920300716527 1.9787891154194347e-10 2.0371178953028154e-09 1029.4770066344422 1.4503675918183244e-10 2.269231933369417e-09 1564.5908983146014 1.0975840796102616e-10 2.225518596709056e-09 2027.6520387388548 9.526083615414643e-11 2.219127343497372e-09 2329.527466992299 +r_3380 inositolphosphotransferase (PI (1-16:0, 2-16:1) MIPC-B (C24)) -3.689631776050131e-10 3.041367711694094e-09 -824.3011488127349 -4.1924078152557525e-11 2.258565337980512e-09 -5387.274896687815 -2.8305419650189384e-10 3.013608889588465e-09 -1064.6755733820405 -8.849590470961782e-11 2.7336283200757604e-09 -3088.988500705917 -1.2449671603929592e-11 2.2610129343503557e-09 -18161.22550282124 -2.3845746886964867e-10 3.1423819984782522e-09 -1317.7955856757062 -8.745898648411859e-11 2.4552171933137863e-09 -2807.278350703986 -2.1396144184103118e-10 2.5855085027511275e-09 -1208.399270683596 -2.3852941974230984e-11 2.2977484379919156e-09 -9632.977099739894 +r_3381 inositolphosphotransferase (PI (1-16:1, 2-16:1) MIPC-B (C24)) -2.6747327050201157e-10 2.5338256206917567e-09 -947.3191904133464 6.164093056081934e-12 2.230488577115561e-09 36185.18664176885 -9.40653963253884e-11 2.6156665889150007e-09 -2780.689489540829 -1.2765334463835463e-10 2.3395873264239304e-09 -1832.7661786317035 -6.297009265954019e-11 2.500079549744837e-09 -3970.2650006599065 -2.7398725473184477e-10 2.762551136623772e-09 -1008.2772424314117 -1.0106595469702644e-10 2.824373013426998e-09 -2794.584013868813 -5.367326840723109e-11 2.558235379004645e-09 -4766.311899612189 -2.937667347179311e-10 2.4318450485326243e-09 -827.8149841804359 +r_3382 inositolphosphotransferase (PI (1-18:0, 2-16:1) MIPC-B (C24)) -1.1522027142863388e-10 2.74799191579997e-09 -2384.989968976115 -1.5635249363235339e-10 2.819059031755564e-09 -1803.015075911925 -3.911468295589742e-11 2.101719339094519e-09 -5373.22350653909 -6.271887162834474e-11 2.2936161023761696e-09 -3656.9792198551104 -1.5837474956885271e-10 2.526990541367026e-09 -1595.5766612078703 -9.6854839605135e-11 2.5093213114901357e-09 -2590.806325961948 -1.7718789897367324e-10 2.1710796243345264e-09 -1225.2979108111144 -1.6352856573067668e-10 2.378257096122186e-09 -1454.3374030681923 -2.1406836764518194e-10 2.6668076105917755e-09 -1245.773787097777 +r_3383 inositolphosphotransferase (PI (1-18:1, 2-16:1) MIPC-B (C24)) 4.969903589703769e-11 2.2385509466873354e-09 4504.214028064806 5.8027917453614486e-11 2.748704855500095e-09 4736.866281126346 -4.8392766987204595e-12 2.6086116379847358e-09 -53904.9903609453 1.6887722620307885e-11 2.399737194921206e-09 14209.951506637522 -1.2341618968433936e-10 2.909900325078207e-09 -2357.794656050261 1.0742884477076382e-10 2.207096740174011e-09 2054.4731211469384 7.834146468504059e-12 2.234104374586061e-09 28517.521130960755 4.203684462281405e-11 2.240851181419505e-09 5330.683597986706 4.610717233937917e-12 2.333154209506601e-09 50602.84747746075 +r_3384 inositolphosphotransferase (PI (1-16:0, 2-18:1) MIPC-B (C24)) 8.956663395853504e-11 2.250800479633655e-09 2512.9899161730978 -1.0931636388000172e-12 2.618128447509366e-09 -239500.1401970639 5.6836402432478405e-11 2.288223862942013e-09 4025.982935250733 1.2184249395896868e-10 2.128869642148729e-09 1747.2308494158376 -3.996439053337192e-11 2.6800097381363954e-09 -6705.994267317742 -1.056579663756514e-11 3.244639307660036e-09 -30708.89417012057 6.649307457083384e-11 2.227973312371156e-09 3350.684754391584 4.5533313024197446e-11 2.2367814574910273e-09 4912.40656330531 -1.2403286232232347e-11 2.4566297721129444e-09 -19806.28138475847 +r_3385 inositolphosphotransferase (PI (1-16:1, 2-18:1) MIPC-B (C24)) 1.0690952262242415e-10 2.298502157824981e-09 2149.950819575424 -1.3417529503307358e-10 2.838374757412705e-09 -2115.422780857727 -3.0584041861694715e-10 3.403420207977203e-09 -1112.8091647820588 -1.8333804778654968e-10 3.256072831568796e-09 -1775.9940562690304 -6.843415164578106e-11 2.6080008156033597e-09 -3810.963901624025 4.445709026255224e-12 2.52027256486311e-09 56690.0026515236 -8.337853642049438e-11 2.520328290222279e-09 -3022.754294356724 4.041064589000784e-11 2.215285234852002e-09 5481.934737894813 3.790408399827494e-11 1.967622410282493e-09 5191.056484499249 +r_3386 inositolphosphotransferase (PI (1-18:0, 2-18:1) MIPC-B (C24)) 1.7107069870926624e-10 2.2241688261264784e-09 1300.14598812532 3.697376891001267e-12 2.585688085888517e-09 69933.04069654367 6.709046112017414e-11 2.6968325897552863e-09 4019.696011515931 9.705511528485027e-11 2.952910840680106e-09 3042.509229949921 5.6087777531243856e-11 2.639005648942197e-09 4705.134995716547 1.5535378390628648e-10 2.672908559902637e-09 1720.5300654376122 1.1178015237617032e-10 2.135788646987929e-09 1910.7047195645475 1.5480304459680582e-10 2.7507533829060063e-09 1776.9375208804934 2.533529460953144e-11 2.728904504571101e-09 10771.1575753473 +r_3387 inositolphosphotransferase (PI (1-18:1, 2-18:1) MIPC-B (C24)) 9.617345986460184e-11 2.539710642729467e-09 2640.7603992879203 -3.090208521495817e-11 2.631292733912267e-09 -8514.935855003689 -1.0479834423004875e-10 2.559262421744244e-09 -2442.082878834672 1.069763929944378e-10 2.2915016651075596e-09 2142.062936471138 -2.5798817908410635e-10 3.515289062499943e-09 -1362.5775704064056 1.544184065935665e-10 2.491398592876366e-09 1613.407784626217 7.711589392673254e-11 2.447782752500032e-09 3174.16115908046 1.7326326611133934e-11 2.616629522945961e-09 15102.044314831912 1.5736389133841418e-11 2.5062257720969607e-09 15926.307812935767 +r_3388 inositolphosphotransferase (PI (1-16:0, 2-16:1) MIPC-B (C26)) -2.4753348691696945e-10 2.861825587236921e-09 -1156.1367404794275 1.7297475750702783e-11 2.4336571542563443e-09 14069.435270967017 5.716751332830575e-11 2.069461353588106e-09 3619.995401415228 -7.94257813913484e-11 2.1872305165312044e-09 -2753.804215981504 -7.892189462498628e-11 2.496729898724309e-09 -3163.545313487516 -1.6948396621945856e-10 2.1813863085263347e-09 -1287.0753246957518 -1.1489728729136524e-10 2.456661769973237e-09 -2138.137311931002 -6.578119705781649e-11 2.502686940292172e-09 -3804.5627812040366 -1.0117413220148516e-11 1.9073813660105958e-09 -18852.460846534417 +r_3389 inositolphosphotransferase (PI (1-16:1, 2-16:1) MIPC-B (C26)) -2.5816121233733177e-10 2.683778811903516e-09 -1039.5747632284513 7.036534773625274e-11 2.432397821384514e-09 3456.812052577017 -1.6863087423319182e-10 3.032180372108609e-09 -1798.1169734763678 -6.113205867898247e-11 2.0337116226630776e-09 -3326.751407706606 5.501461466532457e-11 2.019190410384414e-09 3670.28002044173 -2.3283486649842183e-10 2.461831600086071e-09 -1057.3294443007132 4.8290128828242006e-11 2.244089751102244e-09 4647.09829017853 -3.156942206004009e-10 2.743730281718172e-09 -869.1100763580747 -3.457039755597922e-11 2.358798133903689e-09 -6823.173294678289 +r_3390 inositolphosphotransferase (PI (1-18:0, 2-16:1) MIPC-B (C26)) -1.4553651237746529e-10 2.493051546597975e-09 -1713.007619786824 -1.3267645777815115e-10 2.71803768752912e-09 -2048.620933243456 -5.369131355237962e-11 2.615973706455124e-09 -4872.247545039216 -6.429797064201944e-11 2.1818340791945404e-09 -3393.31717223543 -8.861063001174668e-11 2.336933749581803e-09 -2637.306324615915 -6.869653007260306e-11 2.452294503855171e-09 -3569.7501769935443 -1.7692090342448526e-10 2.624745194186997e-09 -1483.569857140884 -1.3406288139144376e-10 2.1926429359332917e-09 -1635.5332014169524 -9.695780786886828e-11 2.5299435096609202e-09 -2609.324164055536 +r_3391 inositolphosphotransferase (PI (1-18:1, 2-16:1) MIPC-B (C26)) 4.9741029440036596e-11 2.496284051632478e-09 5018.561295844869 4.406183278564573e-11 2.834081565884414e-09 6432.055560811098 -3.250240918093644e-11 2.758932284863281e-09 -8488.39318188595 2.7988414923349177e-11 2.315334131323163e-09 8272.473227455295 6.139707020708404e-11 2.139623160338811e-09 3484.8945611283248 9.416953635054459e-11 2.7580812310312998e-09 2928.8465653737385 -8.392167352469706e-13 2.763498268016015e-09 -329294.9427662156 6.231979874849601e-11 2.136161825259783e-09 3427.741854367487 -6.716789074597687e-11 2.6761567945803604e-09 -3984.279936229283 +r_3392 inositolphosphotransferase (PI (1-16:0, 2-18:1) MIPC-B (C26)) 1.6112490733259074e-10 2.523965645017034e-09 1566.4652267616923 1.0316834420472452e-10 2.654789555203156e-09 2573.259826614122 4.510235025183842e-11 2.760923946714757e-09 6121.463585153679 5.1030091954476146e-11 2.43298143397078e-09 4767.738682778072 1.2267151071502302e-10 2.440725817037989e-09 1989.6435633763533 1.3114178961563749e-10 2.6936322885901703e-09 2053.984695866144 5.7642825224291396e-11 2.547908896955118e-09 4420.1665810811055 8.574269810536415e-11 2.375299107662e-09 2770.264010986842 1.0743413832938883e-10 2.454454935360633e-09 2284.6136000415163 +r_3393 inositolphosphotransferase (PI (1-16:1, 2-18:1) MIPC-B (C26)) 1.5513108434457934e-10 2.588749878034447e-09 1668.7499407174123 1.385920164880634e-12 2.965409634578157e-09 213966.8438140923 5.957761581344112e-11 2.392524310288424e-09 4015.810766547416 6.284651791140277e-11 2.352830075202076e-09 3743.771577796808 -2.5316924162303665e-11 2.3251064417224782e-09 -9184.000500283952 8.017856667846304e-11 2.410108980084956e-09 3005.92674567272 -1.2080508489977304e-11 2.76966980026213e-09 -22926.765065891148 5.8144123145423594e-11 2.533803244342026e-09 4357.797671150291 1.2960721835221554e-11 2.46655849720283e-09 19031.027195567203 +r_3394 inositolphosphotransferase (PI (1-18:0, 2-18:1) MIPC-B (C26)) 1.426542991698252e-10 2.1645436843086873e-09 1517.33505187381 1.0348453385536591e-10 2.718158125633977e-09 2626.632236110743 9.22911354057208e-11 2.1569012033334968e-09 2337.0621607931785 1.3090088865292515e-10 2.2252339563161462e-09 1699.9380059337902 9.928646787893567e-11 2.222372755335559e-09 2238.344059177727 1.7899504498444343e-10 2.225799320149353e-09 1243.4977294163637 1.3255180505924624e-10 2.343770263215025e-09 1768.191887064411 1.6602706625453975e-10 2.3689217604351393e-09 1426.8286574451015 2.028909220328583e-10 2.317446023064024e-09 1142.212771199646 +r_3395 inositolphosphotransferase (PI (1-18:1, 2-18:1) MIPC-B (C26)) 1.3883364603855328e-10 2.113302038311789e-09 1522.1829135892156 -1.6429992567550334e-10 3.0001417619758714e-09 -1826.0152885894968 1.2635240275415712e-10 2.625308660242169e-09 2077.767104556145 1.2572680140469155e-10 2.349272650532263e-09 1868.5535814837 1.1616463849180019e-10 2.1286020099106884e-09 1832.4010107955032 1.5142270311440019e-10 2.4731000473103673e-09 1633.2425696045957 9.932380198910316e-11 2.191466314282008e-09 2206.385851522713 1.3625323841500349e-11 2.763358538330773e-09 20281.04851287327 1.0705461300638727e-10 2.3185008073101082e-09 2165.717797860591 +r_3396 inositolphosphotransferase (PI (1-16:0, 2-16:1) MIPC-C (C24)) -1.3549879410070387e-10 2.319357745210253e-09 -1711.718366649437 -6.269128910081798e-11 2.5473191790586804e-09 -4063.274524411469 -5.2436315976266593e-11 2.635808591444608e-09 -5026.685308398881 -1.2552630559226208e-10 2.470422293067769e-09 -1968.0514625295043 -4.2268371332034114e-11 2.3241929124130715e-09 -5498.657362867505 -1.8692136467197707e-10 2.374713976044102e-09 -1270.4347521811746 -1.5114071826442635e-10 3.0132443075404767e-09 -1993.668114153522 -3.0393277022443937e-10 2.751404039631098e-09 -905.2673186900251 -1.005685104246564e-11 2.220593949608604e-09 -22080.4100630706 +r_3397 inositolphosphotransferase (PI (1-16:1, 2-16:1) MIPC-C (C24)) -2.0498216417851047e-10 2.6268890161920277e-09 -1281.5207736339337 2.88207141694478e-11 2.391988018753189e-09 8299.54457301021 -9.230607160270076e-12 2.8728934236425477e-09 -31123.55854561673 -2.082701539516264e-10 2.427520696195943e-09 -1165.5634041350772 -8.226449790594929e-11 2.421172069960987e-09 -2943.1554699684007 -2.406324611435369e-10 2.364118431121398e-09 -982.460313079375 -2.530902900654364e-11 2.306120687715093e-09 -9111.849716237028 -8.641498294317085e-14 2.357853946378747e-09 -2728524.4596175463 2.8183768279024133e-12 2.0716326901121003e-09 73504.46078049543 +r_3398 inositolphosphotransferase (PI (1-18:0, 2-16:1) MIPC-C (C24)) -8.989012583377496e-11 2.330477292003637e-09 -2592.5843026554007 -9.196873660123567e-11 2.494965326879532e-09 -2712.840709878807 -4.4409449100427725e-10 3.0235772816707062e-09 -680.8409793224806 -7.101648320823903e-11 2.3311669583107446e-09 -3282.571669277327 -1.2556323669379488e-10 2.333289430913539e-09 -1858.258430055941 -7.832154657483511e-11 2.35812231954575e-09 -3010.821954712805 -1.3205079445830782e-10 2.968262246559877e-09 -2247.818544928968 -1.3302692146047038e-10 2.1745910734114157e-09 -1634.6999912026124 -7.096336352818636e-11 2.125368283363775e-09 -2995.0219066484738 +r_3399 inositolphosphotransferase (PI (1-18:1, 2-16:1) MIPC-C (C24)) -1.5582730708578876e-10 3.344153815170037e-09 -2146.064048536085 -2.6837539877333157e-10 3.5753025880686483e-09 -1332.202058910895 2.3201237788552488e-11 3.079522499173618e-09 13273.09571687187 -1.7257615281066995e-10 2.613656786088405e-09 -1514.494756964364 4.996594443385752e-12 2.667575073841078e-09 53387.864555873326 1.293805600901702e-10 2.5349510238776802e-09 1959.2982300517 -2.7146570193912014e-11 2.880066333161738e-09 -10609.319382113445 4.1007274081746976e-11 2.2196298648713096e-09 5412.771062145054 -1.1793475831273685e-10 2.6635111029493964e-09 -2258.461492655419 +r_3400 inositolphosphotransferase (PI (1-16:0, 2-18:1) MIPC-C (C24)) 8.477013894500484e-11 2.8143615990849557e-09 3319.9917259906706 4.066057086037566e-11 2.498612370560988e-09 6145.049903851506 9.744083597615111e-11 2.0876543855482846e-09 2142.484067007844 1.4237322038463127e-10 2.235810545022761e-09 1570.387000436291 1.961146484579006e-11 2.6156647895474856e-09 13337.426908775677 8.578561981172962e-11 2.293766532158645e-09 2673.8357048566945 1.1563572089570384e-10 2.68811631613997e-09 2324.641810781361 1.484201985534873e-11 2.6850903433599284e-09 18091.13833244391 -2.2329601498802124e-11 2.6501148324404796e-09 -11868.168953138937 +r_3401 inositolphosphotransferase (PI (1-16:1, 2-18:1) MIPC-C (C24)) 7.054461764551268e-11 2.5491204125232354e-09 3613.486751508936 -1.0086385686149476e-11 2.598166040799937e-09 -25759.13832412449 -1.9778045338558896e-11 2.792709614964943e-09 -14120.250849664752 3.60531157419166e-11 2.621103429686247e-09 7270.116259713058 -4.191929375878691e-11 2.6021902571373033e-09 -6207.619508360265 1.5489615621624782e-10 2.09739068601149e-09 1354.0624488340177 -2.5319417770247424e-11 3.015795517307948e-09 -11910.998683594442 2.8946749964838438e-11 2.244972367250465e-09 7755.524782496926 4.318218231813922e-11 2.0496176138772376e-09 4746.442870295302 +r_3402 inositolphosphotransferase (PI (1-18:0, 2-18:1) MIPC-C (C24)) 1.7306249035789246e-10 2.5283408304740388e-09 1460.9409729661468 1.1271269260090146e-10 2.674442564461393e-09 2372.7962687673416 1.1384317946577616e-10 2.1910500994756442e-09 1924.6213165842964 1.3620395675342654e-10 2.324488839699543e-09 1706.6235776891738 8.448992935360497e-11 2.469007009967046e-09 2922.250058505582 1.9804859899489547e-10 1.781291183766475e-09 899.4212495350124 3.3198512082885785e-11 2.615730042604446e-09 7879.058061619831 6.634920851615803e-11 2.2876477757768204e-09 3447.890075764369 8.67100055213364e-11 2.1774534062954996e-09 2511.190482809625 +r_3403 inositolphosphotransferase (PI (1-18:1, 2-18:1) MIPC-C (C24)) 1.2061038072275508e-10 2.5265222848535446e-09 2094.780125652049 7.602756448330789e-11 2.534944076928783e-09 3334.2434341499106 7.413595814688716e-11 2.643229927213776e-09 3565.381757091057 8.608518365215715e-11 2.608401941301156e-09 3030.0242511427746 1.7130165620301462e-10 2.4258434251701124e-09 1416.123742723874 4.627034139015816e-11 2.8083759202325877e-09 6069.494704073953 9.340372396774492e-11 2.2280081077746303e-09 2385.3525460548303 -9.280077281828473e-13 2.245257747448474e-09 -241943.8631017614 1.1799914387299042e-11 2.295363628553333e-09 19452.375273366142 +r_3404 inositolphosphotransferase (PI (1-16:0, 2-16:1) MIPC-C (C26)) -2.2312795133424479e-10 2.904355961116193e-09 -1301.6549220969096 -1.22414748037243e-11 2.747149062631136e-09 -22441.32432307384 -2.2036660713307968e-10 2.7836581212080524e-09 -1263.19416422607 -7.512464320023359e-11 2.648750441329816e-09 -3525.80768240052 -8.974462467321053e-11 2.6161231394006264e-09 -2915.0750241886744 -1.6637294246383966e-10 2.714063170994044e-09 -1631.3128389755636 -9.466701689662907e-11 2.5829425816166634e-09 -2728.4503793302024 -2.4084685732115167e-10 2.48166288812686e-09 -1030.3903965073305 -3.6474814729491957e-11 2.504045700815244e-09 -6865.1361751553495 +r_3405 inositolphosphotransferase (PI (1-16:1, 2-16:1) MIPC-C (C26)) -2.1025373404857307e-10 2.7561695248689116e-09 -1310.8778007396425 6.796074824512974e-11 2.497948192508116e-09 3675.574882575144 5.65309162445414e-12 2.639970057092486e-09 46699.580202671845 -1.5630128075262562e-10 2.5245147607822404e-09 -1615.1593567411203 -3.5115563820854906e-11 2.460992022614147e-09 -7008.265722769285 -2.8286164958413485e-10 2.8131857638081555e-09 -994.5447776127024 4.935461167423369e-12 2.676436238975898e-09 54228.696127563126 -6.598101498941714e-11 2.5688157174885392e-09 -3893.2649306782528 2.24824744995684e-11 2.260003336519249e-09 10052.289113294157 +r_3406 inositolphosphotransferase (PI (1-18:0, 2-16:1) MIPC-C (C26)) -1.7992932400395712e-10 2.706376293450709e-09 -1504.1329746735385 -3.2100624630195823e-10 3.316877413284086e-09 -1033.2750379455315 -6.632119522209897e-11 2.7850973064484513e-09 -4199.407590773371 -8.058861225012553e-11 2.529818820897125e-09 -3139.176553934498 -5.292438269667664e-11 2.53714820195858e-09 -4793.911752357386 -1.1802135131507662e-10 2.7596551305033683e-09 -2338.26769457675 -1.3857739352964953e-10 2.9447383659809592e-09 -2124.9774519326006 -7.026764854445989e-11 2.3401660400202233e-09 -3330.3605407252926 -1.963620879338984e-10 2.824541936921107e-09 -1438.435477357491 +r_3407 inositolphosphotransferase (PI (1-18:1, 2-16:1) MIPC-C (C26)) -1.2811709181215878e-10 3.0711824316450964e-09 -2397.168393541096 5.797023245360827e-11 2.675897422395627e-09 4615.985324083464 6.055563084129085e-11 2.798129254662157e-09 4620.758162020841 -1.0823349244306792e-10 2.6380002618756355e-09 -2437.3234221036096 8.688507540003595e-11 2.432999088637565e-09 2800.249729237801 1.5160587112251518e-10 2.496272883227283e-09 1646.55422955883 2.231469259894733e-11 2.8072968497170007e-09 12580.486319804517 4.0991405094992616e-11 2.389255538653934e-09 5828.674408981891 -1.92997983255594e-10 3.264061511129692e-09 -1691.2412534420014 +r_3408 inositolphosphotransferase (PI (1-16:0, 2-18:1) MIPC-C (C26)) 1.1410568378520139e-10 2.771386530294275e-09 2428.7892051996987 8.775302159386843e-11 2.721995542260663e-09 3101.882411364006 8.206816920363379e-11 2.671578575937818e-09 3255.316405693045 1.1829724353391971e-10 2.6999164491635992e-09 2282.315604749864 3.967406610132168e-11 2.829457027239912e-09 7131.754582486956 1.8666454346769846e-10 2.445251671431897e-09 1309.971152531727 6.113659819045033e-11 2.505742171586047e-09 4098.596005914915 6.354015936462261e-11 2.579088924881931e-09 4058.9903309526408 1.33402839829469e-10 2.5362893672613713e-09 1901.2259188061887 +r_3409 inositolphosphotransferase (PI (1-16:1, 2-18:1) MIPC-C (C26)) 3.891477402105384e-11 2.727537935394998e-09 7009.003659945023 2.1817906714017812e-11 2.820958329269169e-09 12929.555370482578 -8.762780366933319e-11 2.547023348722421e-09 -2906.6383522902265 1.7112025064209778e-11 2.53637293525933e-09 14822.1670184683 4.703528127369919e-11 2.532761465491213e-09 5384.811989861454 4.5276299489282057e-11 3.170097021091842e-09 7001.669873312587 -1.4394954518867095e-10 3.3381631437568293e-09 -2318.9813759964195 9.131263148217159e-11 2.358662332306207e-09 2583.0624898448204 5.4354704927711446e-11 3.208928731964352e-09 5903.681633875187 +r_3410 inositolphosphotransferase (PI (1-18:0, 2-18:1) MIPC-C (C26)) 1.351958025868976e-10 2.49345752768973e-09 1844.330578301092 1.0835041979748604e-10 2.7197399477612e-09 2510.1332812965293 1.220467791564077e-10 2.4337610519719246e-09 1994.1214907875324 2.3156481955752816e-10 2.0965955548550123e-09 905.4033159532466 1.4324921441422614e-10 2.4970926790751067e-09 1743.1807143140038 1.2273546804245158e-10 3.161253354805514e-09 2575.6640726803626 1.2430027567752775e-10 2.484296961252043e-09 1998.625463789844 1.4707941718410928e-10 2.1159346076325928e-09 1438.634071403705 1.0453302239578376e-10 2.215925909736792e-09 2119.833387526896 +r_3411 inositolphosphotransferase (PI (1-18:1, 2-18:1) MIPC-C (C26)) -2.249675923400525e-11 2.794408210340261e-09 -12421.381147718112 2.3983984018140678e-11 2.757143954376316e-09 11495.771312601384 9.281455998541184e-11 2.821528181556193e-09 3039.9628915976846 5.2521883553168586e-11 2.421457842393485e-09 4610.378909854237 7.314132182004137e-11 2.686927225220218e-09 3673.6104275380703 1.6607664809740198e-10 2.332652503130408e-09 1404.5638142710682 2.257887799133001e-11 2.7808531477197283e-09 12316.170665289652 8.632221857608426e-11 2.685742132529335e-09 3111.2987789605136 1.1125573908325595e-10 2.626623104578977e-09 2360.8877404637947 +r_3412 inositolphosphotransferase (PI (1-16:0, 2-16:1) MIPC-D (C24)) -1.695180586937969e-10 2.8223421800744713e-09 -1664.9212489936026 -2.7553050415170448e-11 2.5754428338357423e-09 -9347.21490008862 -1.0839467788907424e-10 2.909935874173761e-09 -2684.5744928101044 -1.3595456928923898e-10 2.571680441251622e-09 -1891.5733797666296 -1.7754541543842058e-10 2.738416838098233e-09 -1542.3754149529248 -2.79294583019525e-10 2.9081621931501557e-09 -1041.2526307203211 -1.8255041388912926e-10 2.929088826041396e-09 -1604.536940584729 -4.5197074006029054e-10 3.015376507648961e-09 -667.1618846934042 -4.906245124508605e-11 2.5682311099904677e-09 -5234.6163813975645 +r_3413 inositolphosphotransferase (PI (1-16:1, 2-16:1) MIPC-D (C24)) -1.935271502798969e-10 2.580290919554657e-09 -1333.296602478154 1.62165254026657e-11 2.446434893192005e-09 15086.060869672216 -1.7193152598907807e-10 2.842388482459158e-09 -1653.2095938238342 -2.26207332503218e-10 3.052422988961633e-09 -1349.3917085637397 -1.1939209520715951e-10 2.5488223077569034e-09 -2134.8333851871794 -2.4995544498429273e-10 2.483277924485541e-09 -993.4882293288672 2.126840594421108e-11 2.813555441846624e-09 13228.802615611305 -8.3461996434379e-11 2.584758861095749e-09 -3096.92910728296 -1.9177337059666608e-10 3.290456899144898e-09 -1715.804904980953 +r_3414 inositolphosphotransferase (PI (1-18:0, 2-16:1) MIPC-D (C24)) -2.0165279771523175e-10 2.985184637854769e-09 -1480.3586519391413 -1.7307709390257374e-10 2.972251889064992e-09 -1717.299396497894 -1.3048649896539775e-10 2.772190163629678e-09 -2124.5034433522537 -1.6819822397071854e-10 3.1357746337479793e-09 -1864.3327852818963 -3.0494547679678996e-10 2.950108583982671e-09 -967.4216568060684 -2.194204744395869e-10 3.0086106114389155e-09 -1371.1622031276197 -4.044733748178251e-10 3.368441773574065e-09 -832.7969115621544 -1.4600591280425428e-10 2.65591282493881e-09 -1819.0447043740696 -1.8681014557770666e-10 2.861649542300341e-09 -1531.849104581952 +r_3415 inositolphosphotransferase (PI (1-18:1, 2-16:1) MIPC-D (C24)) 4.289843439551514e-11 2.594829805257264e-09 6048.775070282153 -8.00371906254827e-11 3.009212825075171e-09 -3759.7681797155446 2.1914232359804453e-11 2.633822816841288e-09 12018.77744835955 -6.40949549270832e-11 2.6079659386151716e-09 -4068.909856605861 -2.6611055072048107e-11 2.364343106198929e-09 -8884.815351355246 -8.04819440223242e-11 2.804666323371778e-09 -3484.839186530852 -5.1759220969032064e-11 2.504143967088357e-09 -4838.063479716216 4.301634775965062e-12 2.4263800429353404e-09 56405.99840071237 -9.566293648155824e-11 2.7347545959215166e-09 -2858.739963986699 +r_3416 inositolphosphotransferase (PI (1-16:0, 2-18:1) MIPC-D (C24)) 1.0122542958434939e-10 2.985548835870456e-09 2949.4059428837986 1.6543918148078453e-11 2.8915431830212315e-09 17477.982888576364 6.492943601754799e-11 2.471916352860977e-09 3807.081201495284 4.099209490895885e-11 2.370714565700161e-09 5783.345718157088 3.3554677327222e-11 2.59020813896627e-09 7719.365362112735 1.65469272354389e-11 2.965803322586215e-09 17923.589560690714 1.8291643767751602e-12 2.7393731433680157e-09 149760.9060262569 4.742230542086689e-11 2.8192015287749756e-09 5944.885015089255 -3.0747753310408755e-10 3.295969787876876e-09 -1071.9384127363614 +r_3417 inositolphosphotransferase (PI (1-16:1, 2-18:1) MIPC-D (C24)) 4.172003493757608e-12 2.8924171668926127e-09 69329.21248077606 -1.0731570386130231e-10 2.943486896960097e-09 -2742.8296055946653 -9.01645310950261e-11 3.007984593764033e-09 -3336.10629061428 -1.3642691507698238e-11 2.5795159685666195e-09 -18907.676444278328 -1.2939341492414502e-10 2.687779215557112e-09 -2077.214839049408 -2.980811814631339e-11 2.750081223884233e-09 -9225.947140927974 -1.4184049061483927e-10 2.9063358009962994e-09 -2049.0170249680737 -8.111252949374491e-11 2.570013508433729e-09 -3168.454398443978 -3.73990420678401e-11 2.5827127669347555e-09 -6905.825989472767 +r_3418 inositolphosphotransferase (PI (1-18:0, 2-18:1) MIPC-D (C24)) 9.793061905121328e-11 2.588519681495729e-09 2643.217929769289 6.692364648148312e-11 2.6500794939701034e-09 3959.855198122453 1.0715211933743502e-10 2.459821144854796e-09 2295.634617462414 2.1738228168251838e-11 2.5252551615216715e-09 11616.655883710644 9.402793493264862e-11 2.854568539804228e-09 3035.872841245457 1.3507247829114268e-10 2.6766847493087047e-09 1981.6655348095635 -1.3860937203519946e-10 3.256995859881084e-09 -2349.765973295066 7.708175749869403e-11 2.704622700799286e-09 3508.771450683529 -8.605350036325025e-12 3.0905285622501884e-09 -35914.03660751053 +r_3419 inositolphosphotransferase (PI (1-18:1, 2-18:1) MIPC-D (C24)) -4.152863877111888e-13 2.979027808667006e-09 -717342.994333533 -1.2415167323869272e-10 3.647841161384777e-09 -2938.2134499077406 -7.666939360589192e-11 2.7506191348419842e-09 -3587.6364810985065 -2.5806119698341728e-11 2.635854079453874e-09 -10214.065928025791 2.090635850039448e-11 2.7171553326980583e-09 12996.789147410766 1.0103602335400542e-10 2.590987334772326e-09 2564.4193513972173 -9.848321004298303e-11 3.098484515166419e-09 -3146.205849519004 9.011567675628254e-11 2.264093279249185e-09 2512.429979716421 -1.1588657591116495e-10 2.832522702843699e-09 -2444.2198594382694 +r_3420 inositolphosphotransferase (PI (1-16:0, 2-16:1) MIPC-D (C26)) -2.274958350812415e-10 3.0066129670976044e-09 -1321.6123126051552 2.9657682929671926e-11 2.794430926461954e-09 9422.283369501469 -4.0297632863170416e-11 2.619845637463807e-09 -6501.239530270737 -1.1527556861412303e-10 3.0107998408607647e-09 -2611.8282278348224 -7.920774591316609e-11 3.1838967155176836e-09 -4019.678478173242 -2.449126134892435e-10 3.047123786589937e-09 -1244.167763831309 -1.3416517793988623e-10 3.153049984627612e-09 -2350.1254446517864 -6.777487360068413e-10 3.8864259476395e-09 -573.4316777243343 -2.7660254080724235e-10 3.4429955639366703e-09 -1244.74473513098 +r_3421 inositolphosphotransferase (PI (1-16:1, 2-16:1) MIPC-D (C26)) -2.367914273484746e-10 3.2999609146317486e-09 -1393.6150271924137 -9.997311882869887e-11 3.074447045876021e-09 -3075.2737154714546 5.6885240964739206e-11 3.133268607583456e-09 5508.051920753292 -1.7831273905495182e-10 3.0159928369776114e-09 -1691.4062634908842 -2.706015045175264e-10 3.577723145119009e-09 -1322.1371963537204 -3.0548374442866056e-10 3.2203480009754434e-09 -1054.1798245266336 3.4247005192830536e-11 2.535310073701966e-09 7403.012495331188 -4.429582210452572e-11 2.9762695773160982e-09 -6719.075154069692 -1.1951717174858445e-12 3.1085773926740166e-09 -260094.6246630736 +r_3422 inositolphosphotransferase (PI (1-18:0, 2-16:1) MIPC-D (C26)) -1.2483143097720756e-10 2.864657093537593e-09 -2294.820359834407 -1.6063992106267002e-10 3.336788979532623e-09 -2077.185395422879 -4.3730614279164315e-10 3.5505012727871596e-09 -811.9029040209059 -9.087342034793392e-11 2.944584308267762e-09 -3240.3141611635283 -2.2898636460293544e-10 3.4773282255600433e-09 -1518.5743620978324 -4.3944300824753087e-10 3.6948897916970164e-09 -840.8120557958104 -2.973702892746301e-10 3.4218476625515797e-09 -1150.7026041163797 -2.0079087398781215e-10 3.29821686704559e-09 -1642.6129343138318 -2.6259065618084126e-10 3.58735805145328e-09 -1366.140784911529 +r_3423 inositolphosphotransferase (PI (1-18:1, 2-16:1) MIPC-D (C26)) 1.276993297297847e-10 2.7189608069902835e-09 2129.189567982604 8.396074636622652e-11 3.144455876906394e-09 3745.149981386137 -2.9972008548920696e-12 3.482965240189548e-09 -116207.26834187996 -1.2399748696969975e-11 2.658465324432346e-09 -21439.670991735285 9.579547068717983e-11 3.090948908610581e-09 3226.612789141229 7.970088632848387e-11 3.348382889055287e-09 4201.18651536078 -3.663884987350739e-11 3.044842098250582e-09 -8310.419428455449 -1.000305416693308e-10 3.226755672779641e-09 -3225.7704686297416 4.564094533233665e-12 3.2711814132711636e-09 71672.07842545558 +r_3424 inositolphosphotransferase (PI (1-16:0, 2-18:1) MIPC-D (C26)) 1.6077475541715542e-10 2.862952634902283e-09 1780.7227431159208 1.2440835106581478e-10 2.92768331554699e-09 2353.285201889848 2.457477697561229e-11 3.12047776116056e-09 12697.888425426136 -5.6970300951213796e-11 3.2983418284735603e-09 -5789.581191256259 5.378005883828828e-11 2.877929912489042e-09 5351.2955817744905 1.6556309225406263e-10 3.088598354795387e-09 1865.511396740416 9.91559324287002e-12 3.264962350477881e-09 32927.5543127549 6.950551812653495e-12 3.280884526941562e-09 47203.22379251537 2.5442298013099807e-11 3.413146533340085e-09 13415.244690486345 +r_3425 inositolphosphotransferase (PI (1-16:1, 2-18:1) MIPC-D (C26)) 1.2401870215991088e-10 3.522994489207224e-09 2840.6961432838098 4.785872140843893e-11 2.815336603198962e-09 5882.598866718853 -2.606210409301477e-11 3.735503235954843e-09 -14333.083862388688 -4.156066640541165e-11 3.042080378500762e-09 -7319.614052446114 1.0112722699596947e-11 3.34722669504161e-09 33099.16423571089 1.65168133265837e-10 2.8622595678954407e-09 1732.9369239093194 -1.0180017067305243e-10 3.25810728050815e-09 -3200.492945117041 3.2158837842891056e-11 2.94581848177018e-09 9160.21435899424 -3.7084871281403004e-10 4.0425641652875065e-09 -1090.0844537418511 +r_3426 inositolphosphotransferase (PI (1-18:0, 2-18:1) MIPC-D (C26)) 1.196436847822584e-10 3.3540117278238604e-09 2803.333693648675 1.2602599458150335e-10 3.143244754265157e-09 2494.1241405814585 1.6816424794939778e-10 3.064078196107574e-09 1822.074687973858 7.695152387074925e-11 2.787087260552707e-09 3621.874032324567 5.1881255004285397e-11 3.150890869047913e-09 6073.27418889086 1.8814519818162792e-10 2.918646591985142e-09 1551.2734952542323 -1.0003748795477792e-11 3.031159830112449e-09 -30300.23936109521 -1.4397037580783398e-11 3.644804449805311e-09 -25316.35018213923 1.7354460531392283e-11 3.219087318801425e-09 18549.048603259405 +r_3427 inositolphosphotransferase (PI (1-18:1, 2-18:1) MIPC-D (C26)) 6.126251674657739e-11 3.536176031991662e-09 5772.169051786824 1.164823155628033e-10 2.9681843830845582e-09 2548.1845623889703 1.6426656874491055e-10 2.900223202165738e-09 1765.5590083393608 3.9435189313287325e-11 2.8340616771509067e-09 7186.631347541156 1.9374711768525016e-10 3.1251835650172593e-09 1613.021965103111 1.4817625136284982e-10 3.120329778747816e-09 2105.823132957278 1.0424431436620664e-10 2.8971951960390787e-09 2779.2356961179985 1.2239845936436018e-11 3.359797228488249e-09 27449.669268194644 -8.172870975441216e-11 3.337082461816013e-09 -4083.1214292305153 +r_3428 IPC synthase (PI (1-16:0, 2-16:1) ceramide-1 (C24)) 2.768030221437073e-05 0.0008748632406044 3160.598586782119 3.776039755965696e-05 0.0013098131179041 3468.7482191755216 4.255063032464866e-05 0.0013450780401914 3161.123654171255 3.7974239989624845e-05 0.0015499845500502 4081.673656862457 7.534465556015818e-05 0.0030753773037025 4081.745786530391 0.0001031768006817 0.0032500554301053 3149.9866332642496 7.631746053861248e-05 0.0037895971638396 4965.57031260542 0.0004020956688131 0.0107273078393362 2667.849636629648 0.000165865548311 0.0067480567786356 4068.389636876672 +r_3429 IPC synthase (PI (1-16:1, 2-16:1) ceramide-1 (C24)) 1.1475268410988296e-05 0.0005551207866309 4837.540759389965 4.3841462423810766e-05 0.0014424747086509 3290.2066420748674 3.5011256144221326e-05 0.001201376128827 3431.399672945738 7.168872839995401e-05 0.0020658847829092 2881.742819294577 0.0001315005649541 0.0039955809297425 3038.4515314706173 8.581680232756689e-05 0.0029213798573681 3404.204978667325 7.926668376678798e-05 0.003794798311467 4787.381193632068 0.0001182133248341 0.0057427569905451 4857.960808227974 0.0002231359295923 0.0077714965158721 3482.8530439142824 +r_3430 IPC synthase (PI (1-18:0, 2-16:1) ceramide-1 (C24)) 1.962670661846476e-05 0.000693406424386 3532.9739108327217 5.037787919878559e-05 0.0015924507508637 3161.0118889286205 3.338597432180865e-05 0.0011805179567349 3535.9697619003355 2.5346445097235383e-05 0.001261713018458 4977.869731308739 7.426958682900464e-05 0.003032288692278 4082.813466108913 6.354642077406249e-05 0.0024728400616722 3891.3915709972 0.0001891249272568 0.0059782625568045 3161.012481811324 0.0005117553290177 0.0120528350806297 2355.194835736017 0.0002543654740965 0.0081456022111483 3202.322264874673 +r_3431 IPC synthase (PI (1-18:1, 2-16:1) ceramide-1 (C24)) 1.2915929099947556e-05 0.0005619038835298 4350.472034815432 4.028906325545543e-05 0.0014240040694816 3534.4680526639627 1.70797695343147e-05 0.0008539046338966 4999.509110360735 2.522936000487206e-05 0.001261345601925 4999.514857616003 0.0001254794181011 0.0039664513785533 3161.0374343270346 6.145096137881118e-05 0.0025082802553586 4081.759176876809 7.544817746638233e-05 0.003772047672961 4999.5212603269965 0.0001143667723079 0.0057178070446202 4999.535205229733 0.0002188774840162 0.0077055699150708 3520.494558727661 +r_3432 IPC synthase (PI (1-16:0, 2-18:1) ceramide-1 (C24)) 2.215806332202372e-05 0.0007825360082051 3531.608321686416 3.024715562832158e-05 0.0012345833300142 4081.6509994687926 1.7351120187007597e-05 0.0008525875748644 4913.732172190773 3.766774754455356e-05 0.0015375066696097 4081.758984370299 9.91053579507036e-05 0.0034936313723695 3525.169016701682 4.1142681443773575e-05 0.0020569313391573 4999.507244000228 7.64716737328055e-05 0.0037815308274749 4945.008580154483 0.0001157319005923 0.0057369631935586 4957.11481812399 0.0002175230405474 0.0076900976597724 3535.3025777957973 +r_3433 IPC synthase (PI (1-16:1, 2-18:1) ceramide-1 (C24)) 2.744725991143369e-05 0.0008676985235804 3161.3302252402736 9.76066929960886e-06 0.0006894238755951 7063.284846898544 1.7640344055271954e-05 0.0008545853172115 4844.493477757241 3.452569077832787e-05 0.0014201088030348 4113.19446771569 7.438355661916396e-05 0.0030361781730575 4081.7867698939135 6.173472264005499e-05 0.0025198178876726 4081.6865775269953 0.0002113230470752 0.0061758271967218 2922.4579534498016 0.0001721282122566 0.0070257115122257 4081.673434072671 0.0001733635677499 0.0067462545244185 3891.391145197266 +r_3434 IPC synthase (PI (1-18:0, 2-18:1) ceramide-1 (C24)) 1.4541553937733028e-05 0.0005833091994863 4011.326450969833 6.039268782389838e-05 0.0017425227022337 2885.320665499773 1.754877092443576e-05 0.0008482764314071 4833.822465742936 3.676636420477319e-05 0.0015017965991073 4084.702503470333 7.523788680122155e-05 0.0030682959732624 4078.126199063642 4.754406315770136e-05 0.0020792241060185 4373.25707548783 3.7769018169824325e-05 0.0026706766572728 7071.077795203628 0.0001479376569757 0.006178522988831 4176.436963473843 0.0001646534874683 0.0067206373792746 4081.685412565303 +r_3435 IPC synthase (PI (1-18:1, 2-18:1) ceramide-1 (C24)) 2.7185951682745303e-05 0.000859614235722 3161.97956118488 2.0117657789628045e-05 0.0010057883888406 4999.530260223619 5.094467316551554e-05 0.0014699275750133 2885.341064487173 2.468920483174965e-05 0.0012343743297877 4999.652026866208 0.0001251311512876 0.0039554635241571 3161.054208687682 3.950059086162323e-05 0.0019763385080197 5003.313785718172 7.37837300960406e-05 0.0036898410543418 5000.887119069409 0.0001644067892178 0.0067213062865774 4088.2169882116336 0.0002747137284404 0.0086820643393038 3160.404246483148 +r_3436 IPC synthase (PI (1-16:0, 2-16:1) ceramide-1 (C26)) 1.8157581824715813e-05 0.0006863841887764 3780.1519795008026 3.0365283226329025e-05 0.0012368246741849 4073.1537557750016 1.7136863217969164e-05 0.000856758365303 4999.505186017436 4.172154539489903e-05 0.0015684617712117 3759.356841569689 0.000126605985972 0.0039803830106271 3143.913757369207 8.188737862775247e-05 0.0028943969184473 3534.6068795348847 7.620358480597069e-05 0.0037895272294615 4972.898898536633 0.0001149385561872 0.0057463569629893 4999.503346491567 0.000166021168531 0.0067406794385104 4060.132510903812 +r_3437 IPC synthase (PI (1-16:1, 2-16:1) ceramide-1 (C26)) 6.042749309790485e-06 0.0003926403044421 6497.709640311599 8.07919719297154e-05 0.0020089967090384 2486.629130411779 1.8032316272151863e-05 0.000850532529574 4716.712577227376 9.27504669859608e-05 0.002347843144832 2531.3545269668625 7.722895502753477e-05 0.0030898414741182 4000.884736840735 0.0001470692070962 0.0038627694023297 2626.4977411631376 0.0001905551801343 0.0059595176244033 3127.4498128062087 0.0002505620487703 0.0081954536167366 3270.827987300988 0.000390495764492 0.0102999165399103 2637.6512824171223 +r_3438 IPC synthase (PI (1-18:0, 2-16:1) ceramide-1 (C26)) 3.3228855530091304e-05 0.0009579135793022 2882.776322027552 3.01660152272778e-05 0.0012312864429758 4081.700661154884 1.7084136368917414e-05 0.0008541299199794 4999.549883794299 6.303884816083471e-05 0.0019926696240627 3161.0184548085904 7.543812778315693e-05 0.003079139213127 4081.6750144938346 5.63807288764787e-05 0.0023196945061529 4114.339336114424 0.0001503908766036 0.0053155459257266 3534.486962087916 0.000448373436387 0.0109980056447785 2452.8673539181923 8.837190196786708e-05 0.0045412962283457 5138.846315650216 +r_3439 IPC synthase (PI (1-18:1, 2-16:1) ceramide-1 (C26)) 3.878614949141987e-05 0.0010359842352294 2671.0159394878783 3.0730618361761906e-05 0.0012351546522397 4019.296447925117 1.707965457711e-05 0.000853905037697 4999.545124533366 2.4785258771620323e-05 0.0012391588566475 4999.580065173283 9.232026680764944e-05 0.0032864830636063 3559.8717131676244 0.0001009160121195 0.0031922315614593 3163.255755367787 0.0001557146759411 0.005324855135623 3419.623168746974 0.0001147522704139 0.0057370426495133 4999.502518614488 0.0001098331536501 0.0054911531801432 4999.54066477592 +r_3440 IPC synthase (PI (1-16:0, 2-18:1) ceramide-1 (C26)) 1.2544485369690492e-05 0.0005626006160102 4484.844132144481 3.997177654510108e-05 0.0014128492572141 3534.6171207076272 4.279388756412427e-05 0.0013346416608723 3118.767040906157 4.266916070749946e-05 0.0015747268255234 3690.550269592428 0.0001506175319164 0.00434581343743 2885.3304008722384 -1.7704739611467863e-10 4.195939954833234e-09 -2369.952931764896 0.00011344347024 0.0046303928020235 4081.674152092046 0.0001817595935082 0.0070125746796227 3858.159310476216 0.0002198673605213 0.0077712033170847 3534.496115592777 +r_3441 IPC synthase (PI (1-16:1, 2-18:1) ceramide-1 (C26)) 2.762870412752221e-05 0.0008733628025497 3161.070452377028 1.630533371480155e-05 0.000777331069892 4767.342291108422 8.423299448050183e-06 0.0005956430985631 7071.375085698244 3.7803858174594704e-05 0.0015430424942226 4081.706388528376 0.0001004208754484 0.0035493943287634 3534.5184085592764 8.189931548933521e-05 0.0028947621768301 3534.537693672338 0.0001133706623996 0.0046274276238457 4081.67997425394 5.639751767627477e-05 0.003987921606095 7071.094208411821 0.0001652968187954 0.0067468801082731 4081.675713689237 +r_3442 IPC synthase (PI (1-18:0, 2-18:1) ceramide-1 (C26)) 1.7901453835977395e-05 0.0006781279624509 3788.116700824028 -1.9604089766288132e-10 4.403683932697117e-09 -2246.3087984170743 3.3963943334612776e-05 0.0012004658777365 3534.5303279703253 7.735327446222246e-05 0.0021550157633605 2785.939933820089 7.418503033659222e-05 0.003028787287279 4082.747251752621 0.000122736759466 0.0035413912619038 2885.355029177196 0.0001743768035256 0.0055559559377933 3186.178336487832 0.0002989523399989 0.0090488314810069 3026.8475172457274 0.0004186759008909 0.0105356192709029 2516.414068371973 +r_3443 IPC synthase (PI (1-18:1, 2-18:1) ceramide-1 (C26)) 3.314698030200125e-05 0.0009563954115556 2885.316860968938 1.0038723018518462e-05 0.0007098716942873 7071.334600803624 -5.171675934877294e-10 5.6374998543974435e-09 -1090.07214013134 4.2911424266547685e-05 0.0015830793408089 3689.179205461781 3.5970821852267755e-05 0.0019275636847815 5358.686806484611 6.142837931914618e-05 0.0025073211310782 4081.69832717162 -3.0619848856637976e-10 5.234446133725108e-09 -1709.4944387977766 0.0002637958605604 0.0084561279124771 3205.557469518903 -4.146139596252743e-10 5.669536676450767e-09 -1367.4254194371222 +r_3444 IPC synthase (PI (1-16:0, 2-16:1) ceramide-2' (C24)) 2.4273486278122973e-11 8.787354003180903e-09 36201.45002038996 -9.806144926623868e-11 3.50738388120458e-09 -3576.720421173837 4.248120811748163e-05 0.0013429095032275 3161.184822036469 1.266038333956672e-05 0.0008799823485511 6950.676965688424 0.000100811315161 0.0035524325133096 3523.8430404694427 0.0001434825856164 0.0038325755821329 2671.108529072011 0.0001127102547953 0.0046004748069787 4081.6825543812806 0.0002969814811254 0.0090959766999099 3062.809393178334 0.000104435026769 0.0052015260643173 4980.633629578188 +r_3445 IPC synthase (PI (1-16:1, 2-16:1) ceramide-2' (C24)) 1.679732041371738e-05 0.0006797588443548 4046.829063281598 4.0664679230707326e-05 0.0014282814367931 3512.3391203701926 4.3293914910171306e-05 0.0013547062989177 3129.0917019830927 1.3760295224721758e-05 0.0008959541553858 6511.155035221795 1.8480770146061457e-06 5.332419681590806e-05 2885.3882383939654 4.350681785752977e-05 0.0020664412114078 4749.695135541156 0.0001715393819435 0.005512351990109 3213.4614965115807 1.621421297508323e-05 0.0008087880662389 4988.142609707957 0.0002252201543094 0.0078111845415523 3468.244023498668 +r_3446 IPC synthase (PI (1-18:0, 2-16:1) ceramide-2' (C24)) 1.6474247619023808e-05 0.000672489603325 4082.0656510497065 5.031761879830635e-05 0.001590556601792 3161.033132683857 1.7048702902190368e-05 0.0008523530646686 4999.518553163037 2.4861341245162608e-05 0.0012430894554356 5000.090072282655 7.551271366784313e-05 0.0030821788961278 4081.6688295502568 6.146579183831082e-05 0.0025088868456099 4081.7612050126377 0.0001134749343252 0.004631670485726 4081.668355454138 0.0001720351035388 0.0070120657652356 4075.950559503987 -2.0415416399325398e-11 2.76646261982673e-09 -13550.850816435684 +r_3447 IPC synthase (PI (1-18:1, 2-16:1) ceramide-2' (C24)) 2.590683026040637e-05 0.0008264879851088 3190.231984388991 1.0083275075609836e-05 0.0007129973728348 7071.089179739509 8.423661038373491e-06 0.0005956436743018 7071.07837777916 1.2364662843572136e-05 0.0008743217702071 7071.133125653407 0.000105479715616 0.0035604417489733 3375.475301746642 2.0512559760456577e-05 0.0014504540824384 7071.053536841166 0.0001503679971202 0.0053149588600324 3534.6343383034864 -9.814051202092107e-11 3.188660892366545e-09 -3249.077090291523 0.0001649648987637 0.0067333635231781 4081.694696046373 +r_3448 IPC synthase (PI (1-16:0, 2-18:1) ceramide-2' (C24)) 2.247824174321985e-05 0.0007838931211268 3487.34180405057 2.0279195225147785e-05 0.001007384732334 4967.577466214329 2.549618706339572e-05 0.0010407008902504 4081.790299321185 5.852331040911659e-05 0.00186288037478 3183.142514935211 -2.665260428011193e-10 3.890093691242859e-09 -1459.554815116372 6.165472462604366e-05 0.0025165487202294 4081.680253205539 0.0001126960459438 0.0045998990185455 4081.686256178259 0.0002857329942162 0.0090321038396594 3161.0293604467743 6.227329221970474e-05 0.0039305366049917 6311.753345438174 +r_3449 IPC synthase (PI (1-16:1, 2-18:1) ceramide-2' (C24)) 1.1078494938069896e-05 0.0005538812750639 4999.607601575893 3.024961887004256e-05 0.001234697889153 4081.697341237566 -2.459602441168357e-10 5.043769069793218e-09 -2050.6440331053395 1.779577492534033e-05 0.0009577449356094 5381.866985998157 7.42886376257365e-05 0.0030326385566992 4082.237410218239 6.167120936157009e-05 0.0025172258528483 4081.6871906795263 3.781858457256991e-05 0.0026741877551614 7071.094239473648 0.0001717489423885 0.0070102613885066 4081.6911539684434 0.0001648667253074 0.0067293525097785 4081.692347093052 +r_3450 IPC synthase (PI (1-18:0, 2-18:1) ceramide-2' (C24)) 5.5121809329987385e-06 0.000389783274778 7071.307700452293 4.22384422465725e-06 0.0002986809657442 7071.306370642671 1.6995551158153933e-05 0.0008497039835062 4999.567096113552 1.244294060035004e-05 0.0008798520364355 7071.094082139983 8.935588450531513e-05 0.0032278307248674 3612.331457225325 8.011701366720108e-05 0.0028327224636647 3535.7314682641354 3.776891715836111e-05 0.0026706763151664 7071.0958007311365 0.0001143144697376 0.0057151847754207 4999.528746044032 -9.363729188985148e-11 4.0701833288523864e-09 -4346.754638782456 +r_3451 IPC synthase (PI (1-18:1, 2-18:1) ceramide-2' (C24)) 2.195997501258989e-05 0.000776228693708 3534.743064429697 2.0117628369777853e-05 0.0010057873432011 4999.532373866112 8.515537602658543e-06 0.0006021403007419 7071.077938214145 6.254546293612673e-05 0.0019771009049654 3161.0620693375336 2.4922437531899582e-05 0.0017622988726508 7071.13367380375 4.1040399440821165e-05 0.0020518246975838 4999.524189676815 -9.766786146547468e-11 4.189654037198679e-09 -4289.695683241421 0.0001142866798867 0.0057137848794388 4999.519528521103 0.0001647846774025 0.0067259890769929 4081.6835539631343 +r_3452 IPC synthase (PI (1-16:0, 2-16:1) ceramide-2' (C26)) 1.1063014295062905e-05 0.0005530959483441 4999.504959430322 2.020186238779648e-05 0.0010099952665029 4999.515624426288 2.5749602022441e-05 0.0010434106618155 4052.142867708028 1.4051225683308086e-05 0.0008978308659985 6389.69785436649 2.492252986782997e-05 0.001762298070387 7071.104256802528 6.135289889945599e-05 0.0025043204834911 4081.829104106719 0.0001516333913437 0.0053390576294375 3521.030283714332 5.6997351329617264e-05 0.0040302827107476 7070.999996895243 7.705170279219627e-05 0.004061642928569 5271.321439219958 +r_3453 IPC synthase (PI (1-16:1, 2-16:1) ceramide-2' (C26)) 2.263632695208734e-05 0.0007852164826961 3468.833456762676 4.085297820221457e-05 0.0014282627972922 3496.10447057887 1.787653323007036e-05 0.0008572824203738 4795.574227623988 7.965081236795318e-05 0.0021974239751978 2758.8217996405265 0.0001276934085432 0.0039879734351391 3123.0848018180504 8.481999917123161e-05 0.0029211215351525 3443.9065829928254 0.000113761257874 0.0045937653787053 4038.0754085814174 0.0001868560886583 0.0070852281576689 3791.81016178958 0.000391784883026 0.0103197919835808 2634.0454751273824 +r_3454 IPC synthase (PI (1-18:0, 2-16:1) ceramide-2' (C26)) 5.543638081280713e-06 0.0003919994053262 7071.157957622649 3.019821676193584e-05 0.0012312882311261 4077.3541061474857 1.7108755086398412e-05 0.0008541324855853 4992.370755627629 1.343657407621426e-05 0.0008941004205945 6654.229087884482 4.9336813065752e-05 0.0024555185693531 4977.051448541447 -1.4996364512818606e-10 3.690224547837838e-09 -2460.7460992852666 0.0001134684059641 0.004631400843289 4081.66555609671 0.0001142642405284 0.0057126547476237 4999.512289413587 0.0001103480447132 0.0054916790525429 4976.689044932184 +r_3455 IPC synthase (PI (1-18:1, 2-16:1) ceramide-2' (C26)) 5.542820282327445e-06 0.0003919439349734 7071.200490175296 3.0205159147101608e-05 0.0012328763956564 4081.674887565556 2.195831479311096e-05 0.000918622166462 4183.482089209612 4.92559381294838e-05 0.0017419917221403 3536.61261625156 0.0001004163715724 0.0035492230937156 3534.506413781345 8.225080324615468e-05 0.002907140464846 3534.482765044537 3.781870771891739e-05 0.0026741887802344 7071.073924868049 0.0002295046179841 0.0081117832951766 3534.4749776401068 0.0001649419097858 0.0067317611559674 4081.2921135117977 +r_3456 IPC synthase (PI (1-16:0, 2-18:1) ceramide-2' (C26)) -1.8472127138608487e-10 4.51148450161624e-09 -2442.319970928964 2.0148597489165224e-05 0.0010073451353381 4999.579429187785 2.519018674999372e-05 0.0010150912839893 4029.709243777835 5.0276075769926586e-05 0.0017770280647516 3534.5401118489794 0.000100411657399 0.0035490595844533 3534.5095145176565 6.126163452787974e-05 0.0025005442744746 4081.745930785859 0.0001883837098215 0.0059549208323618 3161.059328326635 0.0002861073974815 0.0090439398264359 3161.0297063430367 0.0003841630935457 0.0102611057918304 2671.028519976644 +r_3457 IPC synthase (PI (1-16:1, 2-18:1) ceramide-2' (C26)) 1.6635619588841102e-05 0.0006774905562195 4072.529746195647 3.30533576412648e-05 0.0012500232431998 3781.8343805389504 2.5503259739109208e-05 0.001040988338463 4081.78542316588 3.784402902118847e-05 0.0015446719260488 4081.679371887128 5.0142755037652784e-05 0.0024921016947863 4970.013500285287 6.169298058620168e-05 0.0025181164563537 4081.690384265489 -2.2509667448628646e-10 4.191473001250585e-09 -1862.076821355236 0.0002290694515899 0.0080964366607652 3534.489913242316 0.0002194172263628 0.0077555431989436 3534.6099882413773 +r_3458 IPC synthase (PI (1-18:0, 2-18:1) ceramide-2' (C26)) -1.9750285557483566e-10 4.9372145795720555e-09 -2499.819339422816 1.289716073898397e-05 0.0007399702469342 5737.466268041241 3.3514849219921256e-05 0.0011850997228977 3536.0437253385726 1.2550751560666918e-05 0.0008874844193611 7071.165539938415 2.512862705584356e-05 0.0017768725957757 7071.10894609153 0.000122490859269 0.0035343048284646 2885.362099307693 0.0001130336031331 0.0046136872228534 4081.695261381629 0.0002292714915823 0.0081035411973647 3534.473972947057 0.0002195340360078 0.0077594187210446 3534.4946333358585 +r_3459 IPC synthase (PI (1-18:1, 2-18:1) ceramide-2' (C26)) 5.536451594543048e-06 0.0003914995622277 7071.308319819557 4.0274976721689e-05 0.0014235112743223 3534.4806879944445 3.0350848993751145e-05 0.0010965149052798 3612.798131299798 3.7602752174133305e-05 0.001534811613854 4081.647020799368 2.511511621982456e-05 0.0017759135338955 7071.094230070689 4.055157215745459e-05 0.0020273714491176 4999.489147413992 7.550194048209264e-05 0.0037747254953231 4999.507921546 -1.5687557788201054e-10 4.589214952519747e-09 -2925.385209399128 -2.0099392490548056e-10 4.404220495464007e-09 -2191.2207035785464 +r_3460 IPC synthase (PI (1-16:0, 2-16:1) ceramide-2 (C24)) 2.215644523559605e-05 0.0007817423031029 3528.2839588682555 3.030283349537044e-05 0.0012368636236288 4081.676467046505 1.7136794378578247e-05 0.0008567579381681 4999.522776787121 3.410945601404435e-05 0.0014052498152345 4119.824762540883 5.0759007446355e-05 0.0025224350454201 4969.433352466608 2.068697630165108e-05 0.0014602897120903 7058.980929822158 3.8305740921854286e-05 0.0026799474808857 6996.203222783126 0.0002289258322195 0.0080913909546509 3534.5032389748 0.0001104747084854 0.0055231855785191 4999.502288114674 +r_3461 IPC synthase (PI (1-16:1, 2-16:1) ceramide-2 (C24)) 2.242710245368483e-05 0.0007848424320264 3499.526671567561 1.061093022767266e-05 0.0007144489392177 6733.141429528342 4.190127544062887e-05 0.001313631200729 3135.0625653158195 3.861965114053339e-05 0.001532316827967 3967.7127646520894 0.0001269482011418 0.0039738719063598 3130.309740993042 6.228024466442067e-05 0.002498687687022 4012.006857849609 0.0002661067150792 0.0070644678718174 2654.749944853117 0.000115913368194 0.0057472704775247 4958.246462049726 0.0002221730305706 0.0077946681987691 3508.377312380499 +r_3462 IPC synthase (PI (1-18:0, 2-16:1) ceramide-2 (C24)) 1.6629363157923875e-05 0.0006787624640927 4081.710511982933 1.992293404650972e-05 0.000996119168377 4999.861797723139 -7.780383599416808e-11 3.743739562382449e-09 -4811.767330679 3.784337133737821e-05 0.0015446421612054 4081.671655082731 0.0001253872986714 0.0039587084920268 3157.18460639248 6.169515911092298e-05 0.0025181971340175 4081.677023459876 3.6960948748443234e-11 5.743330797597659e-09 15538.916050794189 5.525494836071325e-05 0.0039071183316195 7071.074080303573 0.0002205142389612 0.0077755596033248 3526.1031849695605 +r_3463 IPC synthase (PI (1-18:1, 2-16:1) ceramide-2 (C24)) 1.104701943998322e-05 0.0005522993935158 4999.533100457122 -1.9536360345025063e-11 4.247026602082779e-09 -21739.088177518614 1.7645279208062955e-05 0.0008548305704492 4844.528445084681 2.5229486799350804e-05 0.0012613449685198 4999.4872212473965 0.0001023310646916 0.0035580453376936 3476.994350069995 -1.5215367856768502e-11 4.2332930906462265e-09 -27822.482706279498 7.563732785393391e-05 0.0037814937089908 4999.507275420244 0.0001124919199928 0.0056251746219446 5000.514367877449 0.0001047193757847 0.0052427859126712 5006.509896933388 +r_3464 IPC synthase (PI (1-16:0, 2-18:1) ceramide-2 (C24)) 1.1054842497281743e-05 0.0005526924466609 4999.550620434534 3.160189806310784e-05 0.0012356111256023 3909.926938992368 8.538038961354447e-06 0.0006037574527173 7071.383199937559 3.959507741639005e-05 0.0015434806759889 3898.163046273179 5.009735325897099e-05 0.0025046536702172 4999.572846233596 7.031121367365699e-05 0.0024932940166918 3546.083030601984 0.0001131245631357 0.0046174141915921 4081.707865737653 0.0001117171164366 0.0055650062044705 4981.337132548666 0.0001447367869871 0.0060267122456393 4163.9118644899 +r_3465 IPC synthase (PI (1-16:1, 2-18:1) ceramide-2 (C24)) 1.54245636723171e-05 0.0006330610410431 4104.239539555529 1.0083017040633227e-05 0.0007129962765556 7071.259263793407 8.681791145990683e-06 0.0006039450031191 6956.45625382313 -2.362297568984838e-10 4.241125141644559e-09 -1795.339078923541 7.525475624217328e-05 0.0030716914149713 4081.7239578671847 2.39230435775907e-05 0.001474227246692 6162.373286286103 0.0001105029686638 0.0045116365292447 4082.819297796216 0.0001146656656806 0.0057327214265216 4999.510003706726 0.0002197697338644 0.0077677440936243 3534.492196461354 +r_3466 IPC synthase (PI (1-18:0, 2-18:1) ceramide-2 (C24)) 1.6463784726490238e-05 0.0006720667726181 4082.09159548091 4.0217494856264505e-05 0.0014214884619677 3534.5027507258933 3.394118721443624e-05 0.001199664150866 3534.5379738389915 4.989369762308361e-05 0.0017370263934723 3481.4545247669025 0.0001503601681896 0.004338392759501 2885.333803318473 6.468735848392951e-05 0.0025155456832407 3888.774781035013 3.763434957146911e-05 0.0026611696632884 7071.119053711263 0.0001717249361575 0.0070092584154135 4081.677694720053 5.506549091761427e-05 0.0038937263840189 7071.082667444982 +r_3467 IPC synthase (PI (1-18:1, 2-18:1) ceramide-2 (C24)) -1.9342177953845592e-10 5.086245272547401e-09 -2629.613523711873 4.000730261154514e-05 0.0014140776091443 3534.548736950458 2.5546351847287368e-05 0.0010427292988032 4081.715091988572 1.2579590926770969e-05 0.0008895097099914 7071.054338487639 -4.0849315582938727e-10 5.001257219038985e-09 -1224.318485553238 9.355923362736026e-05 0.0030102575581034 3217.4884737652887 0.0001506032882546 0.0053230659134219 3534.4951462299628 0.0001145931563111 0.0057290961901821 4999.509896233805 0.0001100830024721 0.0055036079518257 4999.507488193606 +r_3468 IPC synthase (PI (1-16:0, 2-16:1) ceramide-2 (C26)) 1.110179451164171e-05 0.000555003730852 4999.225397930813 4.0341996943831103e-05 0.0014258822443108 3534.486025310428 4.423358182019383e-05 0.0013528510121751 3058.425197566796 2.786703279004883e-05 0.0012679753406177 4550.090962933683 5.014849742004271e-05 0.0025072275455737 4999.606517765257 2.065156868711681e-05 0.0014602880717335 7071.07578052681 7.971603820359859e-05 0.0037333207259312 4683.274294686039 0.0001875116090402 0.0070941064242698 3783.289184376568 -9.786249110323092e-11 3.6149231630801205e-09 -3693.880180575921 +r_3469 IPC synthase (PI (1-16:1, 2-16:1) ceramide-2 (C26)) 3.861836780383061e-05 0.0010280488789256 2662.0723178873186 5.0244805000660365e-05 0.0015764837379658 3137.605445866834 2.700924739296573e-05 0.001049894862965 3887.168152780398 6.440023136788846e-05 0.0020014221678318 3107.7872320033466 0.0002036407885158 0.0050189464791075 2464.6076631727856 7.576461234895696e-05 0.0026854017711304 3544.4011232605503 0.0002139081054355 0.0061923792658962 2894.878271810609 0.000167152314614 0.0067573340226987 4042.6206710345896 0.0001391744818146 0.0056963381309527 4092.9472534622455 +r_3470 IPC synthase (PI (1-18:0, 2-16:1) ceramide-2 (C26)) 2.213459591413401e-05 0.000782345545936 3534.4921089636314 2.016269864796584e-05 0.0010080341152764 4999.499982003534 5.5016439758214906e-05 0.0014934442835999 2714.5418536046423 6.286357225810336e-05 0.0019871567868076 3161.062464997786 0.000177586472894 0.0046342330814225 2609.564234201219 5.270091856793513e-05 0.0022120842274267 4197.430116090412 0.000111825726132 0.0045653422991591 4082.550998834492 5.6996665867174015e-05 0.0040302826429804 7071.084916392685 0.0003853744548688 0.0102934247219351 2671.0189510192267 +r_3471 IPC synthase (PI (1-18:1, 2-16:1) ceramide-2 (C26)) 2.191254517640272e-05 0.0007746122379645 3535.017186404933 4.941123568106173e-05 0.001562106862427 3161.4405932086465 1.806694089847092e-05 0.0008567349719848 4742.003512378559 2.5000779711371234e-05 0.0012499701802098 4999.724787148496 0.000100419729759 0.0035493424293311 3534.50705140132 9.331658983208294e-05 0.0030113555463388 3227.031283245164 3.781857943540884e-05 0.0026741873255852 7071.094064102863 0.0002868809454525 0.0090683427841752 3161.012583066299 0.0002749243006609 0.0086748821319714 3155.371173488562 +r_3472 IPC synthase (PI (1-16:0, 2-18:1) ceramide-2 (C26)) 1.1054625536369588e-05 0.0005526922260389 4999.646747152182 1.0081927449304317e-05 0.0007129294634606 7071.360779429371 1.696187622218962e-05 0.0008480381437137 4999.671808737406 2.5055127695953542e-05 0.0012526736393001 4999.669746255139 3.915667476248597e-05 0.0020293003059346 5182.514394400999 0.0001037560595125 0.0032525893423786 3134.8427818674463 0.000151956580047 0.0053390513953263 3513.5374813470976 0.0003655423797336 0.0100191109418485 2740.8890178890283 0.0002201502123297 0.0077787129767509 3533.3661023685854 +r_3473 IPC synthase (PI (1-16:1, 2-18:1) ceramide-2 (C26)) 1.662812713399981e-05 0.0006787076106029 4081.684035330424 8.321316619014905e-05 0.002018234803418 2425.379174740431 5.767822252320306e-05 0.0014939041162976 2590.066147923794 3.767216123289766e-05 0.0015376939213152 4081.777819458997 0.0001748747921628 0.0046712253461076 2671.182786457136 6.3060364186632e-05 0.0025216582929356 3998.800713349138 3.781442300996982e-05 0.0026689851896456 7058.114278094407 0.0002858155821638 0.0090348819389943 3161.087954195254 0.0001101650815571 0.0055077195341869 4999.514779398158 +r_3474 IPC synthase (PI (1-18:0, 2-18:1) ceramide-2 (C26)) 5.538294600545498e-06 0.0003916344772451 7071.391204190256 6.042962361242597e-05 0.0017435887911966 2885.3212827858188 4.583869260635365e-05 0.0013660233884674 2980.0662078177625 1.258844693074866e-05 0.0008901522076923 7071.1837019228615 4.9056216367912254e-05 0.0024533163522934 5001.030519545349 3.562524511540546e-05 0.0017953213151837 5039.463754896039 0.0001882161822558 0.0059495907296006 3161.0410211773656 -3.0059367657509553e-10 4.4568792955218115e-09 -1482.692299552873 0.0002202622384354 0.0077851154445179 3534.475768436581 +r_3475 IPC synthase (PI (1-18:1, 2-18:1) ceramide-2 (C26)) 1.1073291062766148e-05 0.0005536080904267 4999.490099995967 5.230020509765898e-05 0.0015975658942623 3054.607321862864 2.782326655230199e-05 0.0010531419976317 3785.112706490029 5.018144976517465e-05 0.0017736762131329 3534.525649284611 7.41475166318186e-05 0.002770564329322 3736.557143348911 6.156092054237677e-05 0.0025127113125728 4081.6662428613454 0.0004208914187637 0.008818226381158 2095.1309501767137 0.0002863129270849 0.0090504002425365 3161.016980505125 5.470120632811846e-05 0.0038679786444542 7071.103005028196 +r_3476 IPC synthase (PI (1-16:0, 2-16:1) ceramide-3 (C24)) 2.772856971478397e-05 0.0008764488383273 3160.8151712924764 3.220816535468005e-05 0.0012400960016885 3850.253462227635 1.713844215666354e-05 0.000849610885522 4957.340216547779 5.05514352368328e-05 0.0017867334429757 3534.486082551144 0.0001003905857124 0.0035483168517089 3534.511554571677 6.28410491508848e-05 0.002515712149452 4003.29431708192 0.0001136941356405 0.0046406173940959 4081.66821265854 0.0001724079037953 0.0070371180579533 4081.6678951707954 0.0001104746627612 0.0055231852493068 4999.504059355245 +r_3477 IPC synthase (PI (1-16:1, 2-16:1) ceramide-3 (C24)) 4.21824807612222e-05 0.0010504565609907 2490.2673859722327 2.040523372714574e-05 0.0010101633116534 4950.510859915489 4.3735230709240056e-05 0.0013548129488081 3097.761065478683 7.994508023372545e-05 0.0021978438227364 2749.192090758959 7.801997848761628e-05 0.0030899880524702 3960.5087214433424 6.0665526601174026e-05 0.0024200496089164 3989.16772754036 0.0001203647413997 0.0046258711259132 3843.211119899217 0.000116872483341 0.0057474517462014 4917.711664795798 5.6237485108411154e-05 0.0039000106394008 6934.895171579309 +r_3478 IPC synthase (PI (1-18:0, 2-16:1) ceramide-3 (C24)) 5.555274948830357e-06 0.0003920004947785 7056.365317454841 5.0003765138672e-05 0.0015808655227841 3161.4929763790537 2.5033258563314604e-05 0.0010223445172674 4083.945023304476 1.244284717771252e-05 0.0008798511234083 7071.139835136144 2.5209293882138784e-05 0.0017624110344321 6991.116223532502 2.0490525586560306e-05 0.0014488996151954 7071.07101316047 0.0001131455341559 0.0046182637369109 4081.702182381547 0.0001715199898305 0.0070009015832636 4081.6826016478303 0.0001654196079874 0.006751881724648 4081.669523215663 +r_3479 IPC synthase (PI (1-18:1, 2-16:1) ceramide-3 (C24)) 5.542964638274092e-06 0.0003919439331184 7071.016300772531 9.409112895008542e-06 0.0006653149364201 7070.963478109283 8.539888565898172e-06 0.0006038637140908 7071.095945001704 2.5229378319274808e-05 0.0012613449706269 4999.508726155768 7.593636421672283e-05 0.0030816797336591 4058.239771480228 0.0001028973587651 0.0032525996827267 3161.013773102734 0.0001886654585368 0.0059637522372485 3161.019660672208 0.0002272444749242 0.0080330866585137 3534.9975664712497 0.0001102634721301 0.0055126251784027 4999.502620322146 +r_3480 IPC synthase (PI (1-16:0, 2-18:1) ceramide-3 (C24)) 2.216979317025868e-05 0.0007835974522613 3534.5275720143823 1.2369315214823056e-05 0.0006184208455633 4999.636882260677 4.4284636485550834e-05 0.0013469711410251 3041.6217630343845 3.7837096486832525e-05 0.0015443925604268 4081.6888816094174 0.0001250939077426 0.0039542843116988 3161.052670794492 -2.4017628040743744e-10 4.8210006464753594e-09 -2007.275921792512 0.0001880460909117 0.0059442722240936 3161.071945325968 5.699656406847379e-05 0.0040302825688351 7071.097415614897 0.0001648903620926 0.0067303433506535 4081.7081515481946 +r_3481 IPC synthase (PI (1-16:1, 2-18:1) ceramide-3 (C24)) 5.926803978044163e-06 0.0003309297133574 5583.611581948122 3.0153573388371696e-05 0.0012307802634123 4081.706163180496 2.1754180321935764e-05 0.0008836424466453 4061.9431923818174 3.745802172828742e-05 0.0015289573340687 4081.788795893861 0.0001000464886452 0.0035361929681405 3534.5498038220285 0.000122901909341 0.0035461809361579 2885.374975189868 3.7722135993203246e-05 0.0026673767221419 7071.117930921337 0.0002870258456796 0.0090683433887676 3159.417009047809 0.0001648981326511 0.0067306551222159 4081.704876825703 +r_3482 IPC synthase (PI (1-18:0, 2-18:1) ceramide-3 (C24)) 3.413746866418459e-06 0.0002413948141562 7071.256997140606 1.0078560952237952e-05 0.0007126695313084 7071.143734564616 1.6995599419955053e-05 0.0008497042454396 4999.55444020401 5.011248837114157e-05 0.0017712383224166 3534.524786114381 2.5128738480835487e-05 0.0017768725864364 7071.077554456565 3.91319726492355e-05 0.0019588219745759 5005.68165099696 0.0001508023703154 0.0053301011350875 3534.494268186573 5.73177014590314e-05 0.004052985913355 7071.089402027002 5.470140204861987e-05 0.003867978763724 7071.077922803764 +r_3483 IPC synthase (PI (1-18:1, 2-18:1) ceramide-3 (C24)) 2.9984030677594315e-05 0.0008897397542529 2967.3787484408617 2.011886748723618e-05 0.0010057882595048 4999.229008009202 2.5546515182738977e-05 0.0010427296124621 4081.690222730381 5.004496716680344e-05 0.0017688555777979 3534.5323974380703 5.01207902867726e-05 0.0025058037632794 4999.529634194121 2.0520141982732507e-05 0.0014510061495538 7071.131139223204 0.0001112772696429 0.0045429160066022 4082.519297229576 0.0001140726030868 0.0057031189339614 4999.551846484475 0.0001100830180845 0.0055036081408914 4999.506950893258 +r_3484 IPC synthase (PI (1-16:0, 2-16:1) ceramide-3 (C26)) 5.5123542091988e-06 0.000389783330839 7071.086436872335 5.641765480587482e-05 0.0016485861734796 2922.1104265183926 3.388181022842042e-05 0.0011975726385103 3534.55919396482 8.74265255181897e-07 6.182311627347697e-05 7071.436947430129 8.091517604643289e-05 0.0031013008697186 3832.780228938692 8.212903880450282e-05 0.002897718070473 3528.250315178573 0.0001900782408996 0.0059897676548431 3151.2116413188564 0.0001500160519816 0.0062498852057964 4166.144304718981 0.0001733627290991 0.0067529892383534 3895.2947230614654 +r_3485 IPC synthase (PI (1-16:1, 2-16:1) ceramide-3 (C26)) 2.248731929313121e-05 0.0007790225361349 3464.274802968292 5.08188833110134e-05 0.0015924482988287 3133.5759368872777 4.3592566307823496e-05 0.0013547764621143 3107.815338394553 6.09118809958886e-05 0.0019091069734519 3134.211162483791 0.0001784628979848 0.0047176284796564 2643.4785789802013 2.507746766628304e-05 0.0014663974708967 5847.470288510655 0.0002024796940852 0.0060254658477777 2975.8370956642248 0.0001752993795153 0.0070380292793237 4014.862630308384 0.0002231916868337 0.0078108892262876 3499.632686635947 +r_3486 IPC synthase (PI (1-18:0, 2-16:1) ceramide-3 (C26)) 1.1107294016975904e-05 0.0005543171016541 4990.568367119699 1.8932496562810945e-05 0.0008547528139968 4514.739042265803 1.7084313044733254e-05 0.0008541303336817 4999.500602952423 2.5236188132537503e-05 0.0012616928374739 4999.538087319982 2.5170822872945887e-05 0.0017798528290121 7071.095124685857 6.17577628797299e-05 0.0025207515359413 4081.6755957471287 3.7825001581771584e-05 0.002674634138109 7071.07475548127 0.0001717639801334 0.0070108677967973 4081.6868538742897 0.0001654200768406 0.0067519000564025 4081.66903640438 +r_3487 IPC synthase (PI (1-18:1, 2-16:1) ceramide-3 (C26)) 5.542764283634494e-06 0.0003919443279737 7071.279021028806 1.2096305265360306e-05 0.0007270343648337 6010.383740196122 3.346715121799699e-05 0.0011836445319915 3536.735243109234 2.50576811016996e-05 0.0012527905071323 4999.626669553786 1.5336929249509772e-05 0.0010844913819533 7071.111591572134 0.0001004037890844 0.0031758158335164 3163.043807884764 3.781865952526154e-05 0.0026741873244536 7071.079086415916 0.0002050849129017 0.0073936395449329 3605.160145776099 0.0001653951987951 0.0067508797550896 4081.666096880404 +r_3488 IPC synthase (PI (1-16:0, 2-18:1) ceramide-3 (C26)) 1.6597142903806126e-05 0.0006774546860191 4081.754853504464 2.0305712285251505e-05 0.0010081804330986 4965.0089538150405 2.4345398100271208e-05 0.0009957305478481 4090.015467181993 5.023693563640455e-05 0.0017756429824469 3534.536810322838 9.995126037613376e-05 0.0035328595437329 3534.5822858443084 8.018652087313436e-05 0.0028362248657314 3537.034447745581 8.178315698023523e-05 0.0037860616390927 4629.3904257178365 0.0001717392258607 0.0070098609183137 4081.6888996560656 0.0002745372208115 0.0086782370391367 3161.04206689456 +r_3489 IPC synthase (PI (1-16:1, 2-18:1) ceramide-3 (C26)) 1.2115095363437772e-05 0.0005574627529157 4601.389722429493 -1.9095527652378086e-10 7.580333562821604e-09 -3969.69054786898 2.2236878413240067e-05 0.0009279417175378 4172.985525636353 -2.793602575189882e-10 4.718868841141344e-09 -1689.1697061886475 7.481481050974617e-05 0.0030539000840014 4081.945891720982 2.029168201952502e-05 0.0014348659255284 7071.202496411241 0.0001131877227662 0.0046177536772344 4079.730172478177 5.731842764895588e-05 0.0040530512646806 7071.113830099104 0.0001102632039949 0.0055126229859848 4999.512789630839 +r_3490 IPC synthase (PI (1-18:0, 2-18:1) ceramide-3 (C26)) 1.10670708621931e-05 0.0005533017838136 4999.532312600032 5.0274556847690497e-05 0.0015891889615884 3161.0203276440834 8.546339709100144e-06 0.0006026013063495 7050.987052479773 2.516712987414384e-05 0.0012582409741251 4999.54099024157 5.879460352625311e-05 0.0025283146259804 4300.2494690716485 6.136845829194481e-05 0.0025049010267902 4081.740191148093 0.0001494261807799 0.0052745983478002 3529.9024041639 0.0001700826379118 0.0069430511757953 4082.163388949609 5.506536493265082e-05 0.0038937263858029 7071.098848732349 +r_3491 IPC synthase (PI (1-18:1, 2-18:1) ceramide-3 (C26)) 2.69499139230364e-05 0.0008525689147506 3163.5311236444027 1.0078531282419904e-05 0.0007126667757961 7071.137210629457 2.5494396210980058e-05 0.0010406034135579 4081.694678886837 3.76020110933278e-05 0.0015348122615122 4081.729186513044 -1.4580215654116615e-10 5.203016975922635e-09 -3568.5459662276 4.111141564899355e-05 0.0020452658377699 4974.934104026614 9.700240335099764e-05 0.0040689888431745 4194.729926897953 0.0002284165666125 0.0080733411260022 3534.481428266043 0.0001628371647614 0.0066477850707358 4082.474096423111 +r_3492 IPC synthase (PI (1-16:0, 2-16:1) ceramide-4 (C24)) 1.1101682988419048e-05 0.0005531019545641 4982.14509584842 3.024096310638484e-05 0.0012343427888058 4081.691394759993 1.643738291014178e-05 0.0007943725347496 4832.719047139392 5.320123601609845e-05 0.0017734741764747 3333.520627111144 7.856579819400018e-05 0.0030847781514527 3926.3626442584496 0.0001239017175752 0.0035558005722206 2869.8557548736107 0.0001885237118473 0.0059428012729641 3152.283187473088 5.74692005714473e-05 0.0040636948865469 7071.083025584913 -6.142747843385532e-11 4.509022102994089e-09 -7340.399147019151 +r_3493 IPC synthase (PI (1-16:1, 2-16:1) ceramide-4 (C24)) 1.1237430151639235e-05 0.0005550823815015 4939.584709414723 3.237309256660784e-05 0.0012415690223707 3835.1881885126168 3.635317921338021e-05 0.0012154985385855 3343.582500586962 1.4415927526443685e-05 0.0008963432996475 6217.72895294671 0.0001778327876978 0.0046763835539559 2629.6520537600804 4.526059341684436e-05 0.0020045924078824 4429.001602830003 0.0001267616387864 0.0046850125847224 3695.923017068519 0.0001171969040446 0.0057397581369515 4897.533926973551 0.0002784131726902 0.0087145700698828 3130.0853999379365 +r_3494 IPC synthase (PI (1-18:0, 2-16:1) ceramide-4 (C24)) 1.1107563725404057e-05 0.000554318123693 4990.456389867598 1.0087951499194876e-05 0.0007133287767791 7071.096414729044 1.708419365592114e-05 0.0008541299188403 4999.533112552576 8.742360472041519e-05 0.002335220035491 2671.1550535569813 0.0001240976495585 0.0039234653817419 3161.595240278444 5.923774688260969e-05 0.0024122677406473 4072.180100684353 0.0001128842206447 0.0046048223163279 4079.24357366058 0.0002057693001831 0.0074109666871326 3601.590072249588 0.0004922481082272 0.0115945244551362 2355.4228571626973 +r_3495 IPC synthase (PI (1-18:1, 2-16:1) ceramide-4 (C24)) -2.5974134872029758e-11 5.088793375635493e-09 -19591.772356257992 3.2979798959121285e-05 0.0012470510813222 3781.2573777904936 2.481113464093157e-05 0.0010133795339939 4084.3740065079655 1.158369606869136e-05 0.000819086077385 7071.02528008199 7.555182295504756e-05 0.0030717575773492 4065.762356491244 0.0001751229105746 0.0041575172341533 2374.056724223275 7.319450223404837e-05 0.0036604673952046 5001.014124667205 0.0003440292592739 0.0099263142382632 2885.3110515113844 0.0001078859247336 0.0053950663001545 5000.713775660649 +r_3496 IPC synthase (PI (1-16:0, 2-18:1) ceramide-4 (C24)) 3.187009878127976e-05 0.00092331661155 2897.125038383767 4.025443248917884e-05 0.0014227882008959 3534.488285925767 1.70765108545851e-05 0.0008537551864877 4999.587994045589 3.865497935616976e-05 0.0015454544193214 3998.07332732354 7.099556936086287e-05 0.0028853381738843 4064.110197100397 0.000105189017962 0.0032154054447392 3056.7881581498364 9.95981688723303e-05 0.0041143132565747 4130.9125490536535 0.0003421316447902 0.0098721590166192 2885.4855044679416 0.0001913731138508 0.0068754488061114 3592.6931781381336 +r_3497 IPC synthase (PI (1-16:1, 2-18:1) ceramide-4 (C24)) 1.1078370409767332e-05 0.0005538810651874 4999.661906043138 2.159735559298999e-05 0.0010132637111865 4691.610076167828 5.843748691728552e-05 0.0015617585070193 2672.52852476344 1.2614388130060025e-05 0.0008919948029486 7071.249066952251 9.659613199265092e-05 0.0034215921441167 3542.162686573229 6.29568290204317e-05 0.0025186958360136 4000.67137307096 7.562726084932056e-05 0.0037810006065687 4999.52076024804 0.0001721282832081 0.0070257128112579 4081.672506291736 9.997804164667924e-05 0.0050248071840646 5025.91079131381 +r_3498 IPC synthase (PI (1-18:0, 2-18:1) ceramide-4 (C24)) 1.2580168700979255e-05 0.0005638788996176 4482.2840855365575 8.023612102673294e-05 0.0020045714959736 2498.340485958709 1.6839780559562545e-05 0.0008419777176921 4999.932835906587 5.00631529411308e-05 0.0017695030056941 3534.5416773388265 8.951414879789367e-05 0.0032335457722741 3612.329241464312 6.10804526872913e-05 0.0024931170253877 4081.6937591336696 0.0001704639587531 0.0054811346751081 3215.421438760616 5.5446869331365145e-05 0.0039206941845207 7071.083059874164 0.0002721001738539 0.0086019670316012 3161.323607318657 +r_3499 IPC synthase (PI (1-18:1, 2-18:1) ceramide-4 (C24)) 1.652823685983752e-05 0.0006746346675988 4081.70982373908 5.2910495995683103e-05 0.0015959104657929 3016.245521348218 1.697882233438116e-05 0.0008488639721484 4999.5456423943415 3.673982515263274e-05 0.0015004747952131 4084.0553513238574 -6.300758829009519e-11 6.8210197222461036e-09 -10825.711485482088 4.0948140137307806e-05 0.0020438472291005 4991.306619170184 0.0002246438072944 0.0064824667443663 2885.6645649128072 0.0001633894200417 0.0066852042767622 4091.57721170203 0.0001650177217631 0.0067354795455473 4081.670425202084 +r_3500 IPC synthase (PI (1-16:0, 2-16:1) ceramide-4 (C26)) 3.6390341860189e-05 0.0009817899051222 2697.940868195884 2.0200694972374065e-05 0.0010099406825212 4999.534342270935 5.1255233066592857e-05 0.0014721220689574 2872.140035037544 8.687168854291621e-05 0.0023214733791357 2672.3014345333663 7.502780908316089e-05 0.0030626187690188 4081.9781444293967 8.214404731118223e-05 0.0029033495425401 3534.46127574109 0.0003021655830995 0.007538799701834 2494.923354441328 0.0003592240041419 0.009966605789313 2774.482126582604 6.372496097380266e-05 0.0039460598504552 6192.3299601195 +r_3501 IPC synthase (PI (1-16:1, 2-16:1) ceramide-4 (C26)) 2.3736685625179343e-05 0.0007808136265232 3289.480422215931 5.12711011553725e-05 0.0015967340154472 3114.296317936556 9.75526468131754e-06 0.0006067336707641 6219.551089435411 3.995144202148874e-05 0.0015510452194316 3882.325996136529 5.324247030252972e-05 0.0025236055243462 4739.835529807092 8.237476943056899e-05 0.0028611982410047 3473.391501770948 0.000161988384152 0.0053754401927686 3318.4108977356523 0.0001919372777148 0.0071142498465312 3706.549311957748 0.0004517012537322 0.0110143713888581 2438.4194858550154 +r_3502 IPC synthase (PI (1-18:0, 2-16:1) ceramide-4 (C26)) 1.1065591449675224e-05 0.0005527508872282 4995.222259397859 3.0215110728744148e-05 0.0012332821898741 4081.673573682921 3.870387635692612e-05 0.0012405230751845 3205.16493940948 4.9597625727780936e-05 0.0017499067962133 3528.2067851750944 0.0001256060755552 0.0039704642664823 3161.0447575340995 2.0292039799096346e-05 0.0014348655065465 7071.075755580229 0.00011347496011 0.0046316705630664 4081.6674961365848 -4.6153515237060215e-11 6.851367070689632e-09 -14844.735087888042 0.0002330912696373 0.0078266270679343 3357.752128644984 +r_3503 IPC synthase (PI (1-18:1, 2-16:1) ceramide-4 (C26)) 2.21341896691848e-05 0.0007823236613723 3534.458107863425 2.0117084864360843e-05 0.0010057545714285 4999.504541586655 1.9942837455245207e-10 7.1332805212694284e-09 3576.8633913191165 5.524846824866723e-05 0.0017791616475815 3220.291356447556 0.0001684838080913 0.0045091590113133 2676.31593943372 5.947027482918203e-05 0.0024294714234759 4085.186137871752 0.0001890200393503 0.005974947987892 3161.0129848808488 0.0001862397967206 0.0070775970738334 3800.260308729448 0.000245551928798 0.007987164489523 3252.739462735873 +r_3504 IPC synthase (PI (1-16:0, 2-18:1) ceramide-4 (C26)) 2.756176337568773e-05 0.0008712578158232 3161.1105717270066 3.63806078079228e-05 0.0013077640325207 3594.6734024491625 8.423121874901558e-06 0.0005956438285698 7071.532828519669 3.779366738084162e-05 0.0015426291230423 4081.713233853456 0.0001286067275119 0.0039708147269179 3087.563771925147 0.000143391505105 0.0038301349249183 2671.103090879188 0.0001290539618946 0.0047391853022607 3672.2509194491727 0.0002867317134519 0.0090491477584407 3155.963339212825 0.0002334486998617 0.0078440348178732 3360.067896081752 +r_3505 IPC synthase (PI (1-16:1, 2-18:1) ceramide-4 (C26)) 1.1065163270917551e-05 0.0005532175663293 4999.633107840128 3.011711316287725e-05 0.0012292868732062 4081.6889273488487 1.7052928511608416e-05 0.0008525814733396 4999.61911386219 3.7538497526240616e-05 0.0015322362326016 4081.772935985364 2.492235240053857e-05 0.0017622979716324 7071.15421253083 0.0001026829750077 0.0032458478045896 3161.0379465008896 0.0001889458628731 0.0059726183529067 3161.020972930828 0.0001720774855672 0.0070236560982114 4081.682199770411 0.000446355970513 0.0110108191681414 2466.824663616429 +r_3506 IPC synthase (PI (1-18:0, 2-18:1) ceramide-4 (C26)) 2.2075390133490707e-05 0.0007802598212313 3534.523360688517 4.023539749003332e-05 0.001422116763984 3534.491648395748 3.408711632219882e-05 0.00120480791795 3534.4964547952345 2.324836004916281e-05 0.0011663008620126 5016.7016492618095 -1.4404269151118788e-10 7.023810868893063e-09 -4876.200795197941 0.0001038014512535 0.0032434941961664 3124.7098735113696 4.618652445309668e-05 0.0027215120721422 5892.437468218781 0.0004560297021953 0.0113934043793443 2498.39085579207 5.4701367175764535e-05 0.0038679788539407 7071.082595636535 +r_3507 IPC synthase (PI (1-18:1, 2-18:1) ceramide-4 (C26)) 5.538254316073583e-06 0.0003914993112764 7069.002052509584 5.155491506830071e-05 0.0015876399360162 3079.512271357555 5.9464384308530296e-05 0.0015741767150339 2647.259756136354 5.399628449673222e-05 0.0017690620886674 3276.266330463021 5.0038133140364725e-05 0.0025016600426478 4999.507147139756 1.8980786603874543e-05 0.0013421177576851 7070.928016287597 0.0001864094680352 0.0058933628034917 3161.51473721078 0.000206979800325 0.0074291499826685 3589.3115999737324 0.0001098899149036 0.0054939552540967 4999.508152240542 +r_3508 laurate transport, cytoplasm-ER membrane 0.0002246723383639 0.0020731137615726 922.727638243864 0.0003693629895853 0.0032919788473507 891.2584476984298 0.0002882770513911 0.0028234539268843 979.4237568545724 0.00034505991741 0.0036152534785657 1047.717598062821 0.0008943158445317 0.0084990978851193 950.3463387221532 0.0008316912353367 0.0069569371819933 836.4807618991259 0.0012253558354344 0.0109515688271438 893.7460050746147 0.0030046848703576 0.0227783373175879 758.0940531336641 0.0022904853526163 0.0202310448435026 883.2645369416383 +r_3509 myristate transport, cytoplasm-ER membrane 6.992127329778986e-05 0.0023797095676887 3403.412803359193 0.0002242858364064 0.003025723612918 1349.0480100735165 0.0001307910958486 0.0036582422525521 2797.011699316702 0.0002798371981805 0.0056452764683543 2017.3431213073663 0.000248134751771 0.0091401444700698 3683.5406587879447 1.2707175367784224e-09 1.3322455494881694e-08 1048.4198973642365 0.0001568706803298 0.0140266005127305 8941.505502007343 -0.0011672204762003 0.0155515811180603 -1332.3602040195174 -0.0001816393824322 0.0204323094270616 -11248.832248528515 +r_3510 palmitate transport, cytoplasm-ER membrane 0.0001440174338077 0.0037484291959799 2602.7607192217583 0.0012724925089162 0.0096461470663556 758.0513833099675 0.0008528663382405 0.0078790028291805 923.826217064046 0.0020767429034473 0.0126770753088863 610.4306550340331 0.0025912174888405 0.0227290947771418 877.1588982795973 0.0023587375678343 0.0234652141399295 994.8208931727092 0.0025000293093328 0.0307228691516833 1228.9003587674813 0.0060194486506091 0.0492139710288478 817.5827037558864 0.0013305737534019 0.0443711216812274 3334.735978954928 +r_3511 palmitoleate transport, cytoplasm-ER membrane 0.0007880208847924 0.0066781710613401 847.4611765015381 0.0013028199241528 0.0138788382768717 1065.2921420353816 -0.000143727344974 0.0057816938571749 -4022.681876034656 0.0006998602697676 0.0159741855456735 2282.48212332103 0.0044376586327776 0.0346108531303561 779.9350061474292 0.00184965947681 0.0260300851440515 1407.2906646008134 0.0001710716231928 0.0182144584852134 10647.27050884622 0.0112692983299507 0.0721709161826603 640.4206727835901 -0.0060976843996121 0.0410867060928767 -673.8083410071232 +r_3512 stearate transport, cytoplasm-ER membrane 0.0008097445719951 0.0052759652974709 651.5592052036349 1.5953763590823902e-10 1.3629225046744218e-08 8542.952870746632 0.0010925016586353 0.0073172978133131 669.774526699844 0.0018129700980811 0.0121431427951965 669.7927786039614 0.0010758486650475 0.0095048636516174 883.47589771816 -0.0009640047236107 0.006800022270313 -705.3930446360093 0.0034130152207958 0.0345487651625773 1012.2651944845704 0.0020016123788535 0.0220488022344478 1101.5520521049696 0.0053694599071133 0.0502650274639675 936.1281829738105 +r_3513 oleate transport, cytoplasm-ER membrane 0.0007862908089638 0.0075308520301969 957.7693067683874 0.0014968533688672 0.0129283076326683 863.6990036273321 0.0009497277504706 0.0115361159038888 1214.6760898764453 0.0033023326893364 0.0207451281070879 628.1961891385347 -0.001560442914296 0.0147921571517661 -947.946061739723 0.0041219463874834 0.0273092693334727 662.5333462948242 0.0070103066599111 0.0521268610008153 743.5746184814694 0.0187612033877705 0.0846549955200642 451.22369695776746 0.0112429451924858 0.0761137277699946 676.9910060654258 +r_3514 malonyl-CoA transport, cytoplasm-ER membrane 0.0005645852636865 0.003022583576366 535.3635262510788 0.0013084088127261 0.0058523920874366 447.2907879031322 0.0009342771790202 0.0046129283124334 493.7430150301624 0.0013694700334566 0.0068208837418833 498.067396529065 0.0023810461962617 0.0128111242175416 538.046016816267 0.0024928419806228 0.0114997575055504 461.31112982448326 0.0040634460766244 0.020488388836273 504.2121502272454 0.0067072738635728 0.0325249331990083 484.9203098094929 0.00578965605654 0.0299305972169933 516.9667580370952 +r_3515 lauroyl-CoA transport, cytoplasm-ER membrane 0.0001440906045682 0.0014646381827938 1016.470287693624 -6.531178800596483e-05 0.0023332751851791 -3572.5176976720027 0.0002210358672291 0.0022756335791189 1029.5313641382663 0.0014900922077511 0.0173818795931132 1166.496912251205 -6.4013229803705975 79.74992093569992 -1245.8349809914275 7.393727065733535e-06 0.000244348907678 3304.8137360990486 -0.0007976751085895 0.0115327806680438 -1445.7992413021448 -4.597842389212004 67.67172689170943 -1471.814846252424 0.0061360833239724 0.0577306087252621 940.838083142056 +r_3516 myristoyl-CoA transport, cytoplasm-ER membrane -8.651408630278823e-05 0.0015302836872515 -1768.826040531437 -0.0001483767325312 0.0022865393001915 -1541.036294022465 9.071361278919884e-05 0.0031010271011483 3418.480430665384 0.0006940890613427 0.0152236820711043 2193.332659882634 4.200258281718868 64.67657589517849 1539.8237812344948 7.240745736508038e-10 8.218024487130558e-09 1134.9693506975468 -0.0020555536984191 0.0186926352442591 -909.372265907478 -0.0003739605190487 0.0081236608379927 -2172.331148394262 -0.0055413939595508 0.0392059759357235 -707.5110743236339 +r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane 0.0030976348361462 0.0028222198421334 91.10886180646796 0.0044500085899105 0.0029626160659244 66.57551341904289 0.0103355172427624 0.0037649142263728 36.42695510966532 0.0149207531119835 0.0061333610000399 41.10624278820024 0.021623018675035 0.0093691279055126 43.32941688816906 0.026622523987634 0.0137557662254171 51.66965473223558 0.0295178134561129 0.01132130050777 38.35412987009533 0.0345216459611367 0.0112081563060044 32.467039140086804 0.0419255121651098 0.0373457510089169 89.07643360883206 +r_3518 palmitoleoyl-CoA transport, cytoplasm-ER membrane -0.0001326422833547 0.0019295262927725 -1454.6841655400406 0.0001777483416973 0.0038935664806919 2190.4938428742885 -0.0002935327500668 0.0026274122824311 -895.1002168693539 0.0002782271782826 0.005598183590903 2012.090848010248 -0.0001229997888828 0.0074157227267066 -6029.053215507462 -8.540422562601258e-05 0.0062175406312338 -7280.132318581744 0.0028895142607534 0.03139141822151 1086.3908390375686 0.0001344308910416 0.0243478741648202 18111.81490812941 0.0073628273355271 0.0532412214386249 723.1083795993029 +r_3519 stearoyl-CoA transport, cytoplasm-ER membrane 0.0005121938954601 0.0031594589942005 616.8482331016336 0.0014953481150599 0.0021811256948896 145.8607312185772 0.0029937783129282 0.0027210548515595 90.89032543956084 0.0040407292982113 0.0084182680230302 208.33536230097533 0.0076817772924878 0.0134884839084166 175.5906659987043 0.0094577784363518 0.0067807090891816 71.69452250138698 0.009359216371883 0.0144731266815354 154.6403684502431 0.0110065628102186 0.0120963930735852 109.90164034093152 0.0120808524302914 0.0224042079029017 185.4522106960406 +r_3520 oleoyl-CoA transport, cytoplasm-ER membrane -3.338903320889456e-05 0.0027129184382506 -8125.178172358574 -0.0004209150457073 0.0044329048548249 -1053.1590400564962 -7.335032880044875e-05 0.0035416442322875 -4828.395850716191 -0.0013714238365918 0.0144758731548545 -1055.5360617639892 0.0015453115200936 0.019935619115654 1290.0712158313495 -0.001445248710974 0.013939839815389 -964.528783837789 -0.0012711924095248 0.0131964035587584 -1038.11220550718 -0.0092968689335425 0.0575266552218209 -618.7745103544271 -0.0013393645767653 0.0251382887078704 -1876.881705247207 +r_3521 icosanoyl-CoA transport, cytoplasm-ER membrane -3.1111025389470014e-05 0.0006007813656752 -1931.088281900936 -6.228591100364239e-05 0.0010234968377565 -1643.223678139127 -7.296689497582224e-05 0.001141036897126 -1563.7734036840864 -7.998007034046627e-05 0.0014582619722232 -1823.2816825686584 -0.0001620057566679 0.0029253695117845 -1805.7194830306323 -9.599955620896932e-05 0.0020446712246862 -2129.8757050870645 -0.0003150925152977 0.0049796243096245 -1580.3689608172156 -0.0003656873127447 0.0066671523182599 -1823.1839295212635 -0.0003045178052077 0.0059649132415245 -1958.8060663496144 +r_3522 docosanoyl-CoA transport, cytoplasm-ER membrane -2.0952267272914665e-05 0.0003954455785771 -1887.3641378581256 -4.35461775990459e-05 0.0007292837400819 -1674.736521760614 -4.753725815951705e-05 0.000733855042671 -1543.7470966635567 -5.507502909915512e-05 0.0009601285612291 -1743.3101297152523 -8.79559257198638e-05 0.0017229252862542 -1958.8507222830424 -0.000105388788786 0.0017065511504026 -1619.2909796760582 -0.0001589194698904 0.0027821001278895 -1750.6351674886662 -0.0002631487189125 0.0045057404059279 -1712.2410569001872 -0.0002519332885052 0.0043138876170139 -1712.31346306317 +r_3523 tetracosanoyl-CoA transport, cytoplasm-ER membrane -0.000148178623359 0.0024351690617835 -1643.4010564959988 -3.550215081785959e-05 0.0005906511365993 -1663.7052206487108 -1.8658517421128523e-05 0.0003951931958301 -2118.031068120282 -4.618723799169843e-05 0.0007497999376791 -1623.3920240347677 -5.220023552103273e-10 8.67460289819873e-09 -1661.7938236511443 -7.31078907759866e-05 0.0012163810478199 -1663.8163608728255 -7.663919289871871e-05 0.0016754239633802 -2186.1190077959022 3.137113419477418e-09 2.0462138823106248e-08 652.2600903130509 -1.8446325782388526e-09 1.0640960873543781e-08 -576.8607254948922 +r_3524 hexacosanoyl-CoA transport, cytoplasm-ER membrane -2.727699636610494e-05 0.0003375727720776 -1237.5731093953057 -4.341884496074e-05 0.0005802860074795 -1336.4842109555968 0.0004489747768262 0.0055162205258346 1228.625929685401 0.0007489723714328 0.0162357451291288 2167.7361873935142 2.199789855434607 46.85698506540897 2130.06642201064 -6.753991411763484e-05 0.001024256308054 -1516.5200036678757 -0.0009609059883376 0.0160466409024829 -1669.949099832632 4.601754224359017 67.6736714402114 1470.6059502697087 -0.0012669403381266 0.021036589466263 -1660.4246335204723 +r_3525 H+ transport, cytoplasm-ER membrane -0.0053708786623658 0.0303508352334943 -565.099998370192 -0.0091926344737042 0.0579489331675182 -630.3843945202266 -0.0103227407853536 0.0474337354763778 -459.5071838254336 -0.0143866038182424 0.0689942711339668 -479.5730250559975 -0.0284547873679005 0.1404407006273679 -493.55737159996175 -0.02483137304044 0.1146954242990423 -461.8972302186056 -0.0387089711414211 0.2109003397073379 -544.8358183864536 -0.0565947534693658 0.3200057609174891 -565.433615839859 -0.0591675256045649 0.3072816747447602 -519.3417700081286 +r_3526 H2O transport, cytoplasm-ER membrane -0.0016792925197725 0.0159054755981215 -947.1533643391344 -0.0018413227304932 0.0299174244951031 -1624.7789700118656 -0.0142498373632338 0.0247276422404855 -173.52929447661973 -0.0217284450027313 0.0361875414944014 -166.54455249721104 -0.0252357863402654 0.0724403766118825 -287.0541683747688 -0.0372880068612278 0.0589449795107903 -158.08026352859724 -0.0329056398441884 0.1065812022092457 -323.8994978183632 -0.0299685724816128 0.1627219157423698 -542.9751979084339 -0.0383310788703721 0.1569904294110289 -409.564337966949 +r_3527 CO2 transport, cytoplasm-ER membrane -0.0005645852636864 0.0030225835763661 -535.3635262511165 -0.001308408812726 0.0058523920874366 -447.2907879031399 -0.00093427717902 0.0046129283124334 -493.74301503028937 -0.0013694700334564 0.0068208837418834 -498.0673965291375 -0.0023810461962617 0.0128111242175416 -538.046016816279 -0.0024928419806228 0.0114997575055504 -461.3111298244832 -0.0040634460766244 0.020488388836273 -504.2121502272448 -0.0067072738635728 0.0325249331990083 -484.9203098094917 -0.00578965605654 0.0299305972169933 -516.9667580370939 +r_3528 coenzyme A transport, cytoplasm-ER membrane -0.0038384401891758 0.005506997076011 -143.46965966905913 -0.0066121570908061 0.0084041173967469 -127.10099414353624 -0.0145182508644528 0.0082157864117766 -56.58936802016942 -0.0219896670162668 0.0155692598642625 -70.80261766922254 -0.0315833482825921 0.0241259068984304 -76.3880595640582 -0.03670784958125 0.0189984376794468 -51.75579037228879 -0.0401940108689683 0.0446265672228001 -111.02790256061265 -0.0459820860106031 0.0645692080985257 -140.42252907716392 -0.0645907792214167 0.0758104168128341 -117.37033943027151 +r_3529 NADPH transport, cytoplasm-ER membrane 0.0011834707076125 0.0061069756571277 516.0225443557971 0.0027272483067607 0.0118622929958055 434.9546378450228 0.0019663578895988 0.0093657584567769 476.2997878625069 0.0029091596724344 0.0138487241395914 476.03863998301705 0.0051445345673542 0.0261133025447726 507.5931010451427 0.0051261650574926 0.0232107206157591 452.7891777857104 0.0085633064429116 0.0415131265019239 484.7791770465818 0.0140345018013218 0.0657669471439739 468.60906126200825 0.0122172176512276 0.0605528600394242 495.6354365458924 +r_3530 NADP(+) transport, cytoplasm-ER membrane -0.0011834707076124 0.0061069756571277 -516.0225443558486 -0.0027272483067607 0.0118622929958055 -434.95463784502266 -0.0019663578895989 0.0093657584567768 -476.2997878624707 -0.002909159672435 0.0138487241395912 -476.038639982908 -0.0051445345673541 0.0261133025447726 -507.5931010451556 -0.0051261650574925 0.0232107206157591 -452.7891777857115 -0.0085633064429116 0.0415131265019239 -484.7791770465809 -0.0140345018013218 0.0657669471439739 -468.6090612620089 -0.0122172176512276 0.0605528600394242 -495.6354365458925 +r_3531 O2 transport, cytoplasm-ER membrane 0.0028867447789215 0.0005385207095335 18.65494703465847 0.0046928362247158 0.0008738666929323 18.62129107190868 0.0107523877963335 0.0007696697848397 7.158128960919558 0.0159984747745433 0.0011943630343626 7.465480623585111 0.0226642913228756 0.0024687636955331 10.892746039852463 0.0267676262778039 0.0020961200373298 7.830802834646638 0.0302013362924995 0.0040825293654809 13.517711024246507 0.0355024339700729 0.0054224283441117 15.273398856773222 0.0401821958426512 0.0054090703605747 13.461360802072711 +r_3532 NADH transport, cytoplasm-ER membrane 0.0054241825618805 0.0006143789803209 11.326664862620298 0.0088111905626976 0.0009225340308141 10.4700269986187 0.0203003969206951 0.0008741620989969 4.3061330397227415 0.0301813184176425 0.0013112109706992 4.344445635392823 0.0427081258890953 0.0027508805221559 6.441117386652493 0.0505052514494639 0.0024228257732128 4.797175944440507 0.0567814951818263 0.0043811562821595 7.715817042383474 0.0667838273211027 0.0060062041408138 8.993500944376013 0.0756086973761354 0.0059420785869868 7.85898817622319 +r_3533 NAD transport, cytoplasm-ER membrane -0.0054241825618805 0.0006143789803209 -11.3266648626203 -0.0088111905626976 0.0009225340308141 -10.4700269986187 -0.0203003969206951 0.0008741620989969 -4.3061330397227415 -0.0301813184176425 0.0013112109706992 -4.344445635392822 -0.0427081258890953 0.0027508805221559 -6.441117386652493 -0.0505052514494639 0.0024228257732128 -4.797175944440507 -0.0567814951818263 0.0043811562821595 -7.715817042383474 -0.0667838273211027 0.0060062041408138 -8.993500944376013 -0.0756086973761354 0.0059420785869868 -7.85898817622319 +r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane 0.0017563584198767 0.0017323357950372 98.63224814663964 0.002798659349553 0.0027355149557786 97.7437627846913 0.006158871955457 0.0027255705596929 44.254379363706704 0.0091986447175784 0.0043257848417419 47.02632805760496 0.0130375494817608 0.0076398444506548 58.59877626039098 0.0151994550742028 0.0069257693239883 45.56590542343227 0.0177373041739905 0.0121175670568382 68.31684757713677 0.0217567090990275 0.0193045286633578 88.72908386783875 0.0235998305868125 0.0176128168962265 74.63111581007911 +r_3535 dihydroxyacetone phosphate transport, cytoplasm-ER membrane 5.430027566515089e-05 0.0009038143192705 1664.4746425303986 0.0001104307992614 0.001699743588387 1539.1934132094027 9.780390923343556e-05 0.0014557246669934 1488.4115352883623 0.0001702196776809 0.0023802007437589 1398.3111566106106 0.0003824423656465 0.0052756948545891 1379.4744851739106 0.000140481284256 0.0025351759654872 1804.6360971947856 0.0004364152031054 0.0064907969209556 1487.298534690832 0.000619954389501 0.009540736574142 1538.9416924398188 0.0006379058153801 0.0094334884002128 1478.8215082490667 +r_3536 diphosphate transport, cytoplasm-ER membrane -0.006557672905746 0.0126112119958315 -192.31230616551807 -0.0113698641807752 0.0225710074315792 -198.5160690814893 -0.0119753495521871 0.0184105538877906 -153.73708974055032 -0.0193045141689473 0.0301969380152958 -156.42423192327635 -0.0318500592329801 0.0534014675939845 -167.66520653339384 -0.0305273271396211 0.0465637580311133 -152.53139529100366 -0.0497436956282591 0.0843500244409948 -169.56927581608156 -0.0788476290126226 0.1380331305001848 -175.06313408369866 -0.0595626591863168 0.1112975018063151 -186.8578457153291 +r_3537 phosphate transport, cytoplasm-ER membrane -0.0040996511378745 0.0151243157128424 -368.9171396345629 -0.0075462960267612 0.0279312117745949 -370.13140851542215 -0.0065005620926461 0.0227503344654251 -349.9748812669845 -0.0096391803012009 0.0337594915294465 -350.23197486243265 -0.0188330155890263 0.0677326374366771 -359.64839043697185 -0.0163367453052806 0.0556867839186142 -340.8682872751531 -0.0276171015565239 0.1007275045120923 -364.7287326873645 -0.0413701163502189 0.1536232207338909 -371.33862383512025 -0.0404694935887092 0.1473356595344025 -364.0659827171852 +r_3538 CTP transport, cytoplasm-ER membrane 0.0058882574697017 0.0152327452547925 258.6969970856964 0.0107146102915319 0.028327990538329 264.38656906371494 0.01223593473272 0.0234864585030406 191.94658206402207 0.0180835928259769 0.0345873050129413 191.26345823965315 0.0321246823962652 0.0698547039636925 217.44869910936052 0.0295441567077941 0.0556885199162863 188.4925011299948 0.0457388563311545 0.1033789462417012 226.01996318671783 0.0636825546951112 0.1568492079268741 246.29854860222065 0.0644439581275811 0.1517445902473867 235.4675203949681 +r_3539 CDP transport, cytoplasm-ER membrane -0.0030143115751178 0.0116821334101311 -387.5556032947339 -0.0057774834897148 0.0218523146842981 -378.2324038346408 -0.0046501995371283 0.018055333350307 -388.27007757728927 -0.0068222747995789 0.0264109890895594 -387.1287783832659 -0.0137710712777978 0.0522802403874096 -379.6381511124527 -0.0105311340354186 0.040866054105628 -388.0498906213344 -0.0200287765581699 0.0765739445777604 -382.319630734136 -0.0300271162698291 0.1167272878884081 -388.73958737654186 -0.0289868152234903 0.1131811043844595 -390.4571906634979 +r_3540 CMP transport, cytoplasm-ER membrane -0.0033327064697565 0.0065925025907934 -197.8122781174609 -0.0058346770619306 0.0123100724545209 -210.98121325068905 -0.0084002434444327 0.0103224267325391 -122.88247121433446 -0.0122575745089288 0.0149719048648656 -122.14410651927562 -0.0206658626307613 0.0313862277300092 -151.87475253653602 -0.0210286737783883 0.0257605633195201 -122.5020825897012 -0.0291326498109633 0.0470821333582299 -161.61294514483785 -0.0390772421376327 0.0715829057675862 -183.18310569478345 -0.0406278342684077 0.0688206152454253 -169.39277341431 +r_3541 CDP-ethanolamine transport, cytoplasm-ER membrane 1.0629940231372316e-09 9.333266137040082e-10 87.8016802906818 1.1077999999999308e-09 9.294901561555331e-10 83.90414841628373 1.0515999999999464e-09 7.737293916055381e-10 73.57639707166007 1.0613999999999418e-09 8.693567715496987e-10 81.9066112257157 1.101599999999937e-09 1.0089008951345627e-09 91.58504857794304 1.0603999999999404e-09 7.454280465574487e-10 70.29687349655701 1.029399999999948e-09 7.916192090863433e-10 76.90103060874135 9.844000000002023e-10 7.199029740585901e-10 73.13114324039435 9.91999999999963e-10 7.076977937181103e-10 71.34050339900573 +r_3542 CDP-choline transport, cytoplasm-ER membrane 0.0004587592491787 0.0031935047598895 696.1177928524874 0.0008975491323137 0.0061292380440593 682.8860753571378 0.000814507083641 0.0051032237778334 626.5413622949228 0.0009962552395309 0.0068715049332203 689.7333796162092 0.0023122502188938 0.0153217285201273 662.632806559184 0.0020156500326128 0.0127988183022561 634.9722469264941 0.0034225687369787 0.0226557092729779 661.9504534181384 0.0054218022941505 0.0359116885864846 662.3570288652716 0.0051706899899171 0.0343012058308998 663.3777290417171 +r_3543 ATP transport, cytoplasm-ER membrane 0.0036837270111619 0.0116102285287818 315.17613801462824 0.0064327373789575 0.0206405069714722 320.8666195357291 0.0043896143565954 0.016565442964216 377.3780933472231 0.0080431961425492 0.0279862289289017 347.9491042230322 0.0134964481145119 0.0476393022065491 352.9765891169929 0.0115143044672454 0.0423675374251041 367.9556810889144 0.0240336158552743 0.0765092331525526 318.342581546098 0.0451921905873402 0.1282060767234935 283.6907772277987 0.0241055162822257 0.0970880762066558 402.7628990391874 +r_3544 AMP transport, cytoplasm-ER membrane -0.0036837270111623 0.0116102285287817 -315.17613801458816 -0.0064327373789579 0.0206405069714724 -320.86661953571104 -0.0043896143565958 0.0165654429642162 -377.3780933471966 -0.008043196142551 0.0279862289289019 -347.94910422296 -0.0134964481145139 0.0476393022065487 -352.97658911694043 -0.0115143044672453 0.042367537425104 -367.95568108891393 -0.0240336158552759 0.0765092331525522 -318.3425815460755 -0.0451921905873404 0.1282060767234935 -283.6907772277973 -0.024105516282226 0.0970880762066559 -402.7628990391836 +r_3545 L-serine transport, cytoplasm-ER membrane 0.0013261712324544 0.0007707004814797 58.11470363848144 0.0021099145656534 0.0009846889344792 46.66961167568736 0.0047408044849819 0.0012915033688732 27.24228288604796 0.0070311155085731 0.0018546594315455 26.377883129414144 0.0101045628855116 0.0037438737785572 37.05131850805133 0.011719292547318 0.0029110798176569 24.840064414324285 0.0135797788368845 0.0057824495617578 42.58132353416452 0.0162264973021121 0.0085874303642485 52.9222678460048 0.018206672245519 0.0084356318565714 46.33263972029587 +r_3546 myo-inositol transport, cytoplasm-ER membrane 0.0015477746621293 0.0058321172946459 376.8066138660307 0.0028272122361636 0.0107658387049289 380.7934391065602 0.0028449307106096 0.0090145588682653 316.8639163916014 0.0042302025178248 0.0133670405797658 315.99055892575115 0.0082490482329559 0.0276648380453775 335.37006044955785 0.0072937301250575 0.0225493418216615 309.160627484603 0.0121303009361002 0.0414868430690789 342.0100069043848 0.01742894112317 0.0624372303530713 358.23880470895176 0.0172504706585715 0.0602429715291377 349.2250891091114 +r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane 0.0027562526443729 0.0023147657336978 83.9823496740606 0.0043385969101744 0.0029569078461937 68.15355073110047 0.0095989201586734 0.0038813142125916 40.43490463960705 0.0142207659586933 0.0055774089247235 39.22017239383646 0.0206214431346152 0.0112478508542357 54.54444085610588 0.0236704384641985 0.0087589500294471 37.00375066011127 0.0278822378731318 0.0173759046857903 62.318902682249366 0.0335771073615831 0.0257935312075892 76.81880076751536 0.0374957202512668 0.0253314949489484 67.5583634057345 +r_3548 S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane -0.0027562526443727 0.0023147657336978 -83.98234967406923 -0.0043385969101742 0.0029569078461937 -68.15355073110398 -0.0095989201586734 0.0038813142125916 -40.43490463960725 -0.0142207659586933 0.0055774089247235 -39.22017239383646 -0.0206214431346154 0.0112478508542356 -54.544440856105126 -0.0236704384641985 0.0087589500294471 -37.00375066011139 -0.0278822378731318 0.0173759046857903 -62.31890268224929 -0.033577107361583 0.0257935312075893 -76.81880076751564 -0.0374957202512669 0.0253314949489484 -67.55836340573421 +r_3549 episterol transport, cytoplasm-ER membrane -6.358000000000315e-10 4.845671481479263e-10 -76.21376976217404 -6.640000000000336e-10 4.740769450099322e-10 -71.39713027257653 -5.780000000000271e-10 4.971573524414674e-10 -86.01338277533634 -8.008000000000278e-10 4.01934908080962e-10 -50.19167183828023 -7.288000000000384e-10 4.504343883715423e-10 -61.80493803121825 -8.208000000000207e-10 3.866746221989177e-10 -47.10948126205019 -7.85600000000033e-10 4.123913836765516e-10 -52.49381156778694 -5.186000000000225e-10 5.005038869261513e-10 -96.510583672605 -8.072000000000254e-10 4.0256747523171325e-10 -49.8720856332632 +r_3550 fecosterol transport, cytoplasm-ER membrane -4.858000000000202e-10 5.050241280116707e-10 -103.95721037703782 -4.920000000000204e-10 5.019824671036354e-10 -102.02895672837688 -5.564000000000255e-10 5.020651888856504e-10 -90.23457744170152 -3.9140000000001294e-10 4.889313354348985e-10 -124.91858340186062 -5.740000000000268e-10 4.985716746295847e-10 -86.85917676473196 -7.257714818407222e-10 4.73790374039598e-10 -65.28093014042899 -6.410000000000316e-10 4.847329091351716e-10 -75.6213586794302 -4.662000000000185e-10 5.005074040734135e-10 -107.3589455326884 -6.336000000000313e-10 4.87235589529274e-10 -76.8995564282276 +r_3551 lanosterol transport, cytoplasm-ER membrane -2.5821296198038395e-10 1.128641309923432e-09 -437.0970772602707 -2.189290967612048e-10 7.532174409895676e-10 -344.046292673072 -2.2208308158779024e-10 1.1374021601407571e-09 -512.1516470362635 1.1777637370304164e-10 1.2167558324101182e-09 1033.1068907572376 -1.8726563666155367e-10 8.16379062906005e-10 -435.94707361150927 -1.04891883315033e-10 1.4241327883816347e-09 -1357.7149569375017 -2.607296070940024e-10 8.45381651839394e-10 -324.2369216375967 -1.6975802121309468e-10 9.307099419530703e-10 -548.2568277494024 -4.0762511143385767e-10 8.979242940100942e-10 -220.2818886332997 +r_3552 ergosterol transport, cytoplasm-ER membrane 8.971466724115591e-05 0.0019424860276842 2165.182224287572 0.0002377166252383 0.0043583948641295 1833.4413336715943 0.0001453382103671 0.0030458461512977 2095.695373984976 0.0002586278771318 0.0051590814391753 1994.789384806042 0.0005587816312557 0.0104414637102947 1868.61255385759 0.0005427418342265 0.00925684669604 1705.5708832969235 0.0006182843606031 0.0152328243101226 2463.7246679284726 0.0013498494347016 0.0247127872273261 1830.781018387263 0.001552146491733 0.0259908840610481 1674.5123092104309 +r_3553 zymosterol transport, cytoplasm-ER membrane 0.0001328785707165 0.002422633015468 1823.193162301795 0.0003207976030126 0.0050639929024509 1578.5631983826408 0.0002563136406049 0.0041515659470962 1619.7210329103314 0.0004072434288138 0.0062795550070302 1541.965950272014 0.0004755454773148 0.0097018381740583 2040.149394089182 0.0004951946968867 0.0089794413836663 1813.3153363958647 0.0011105342097562 0.0180551180752133 1625.8047628426475 0.0011911327789115 0.0233320507994218 1958.8119152209224 0.0012775763172422 0.0233209990315994 1825.4094661006293 +r_3554 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane 0.0001173450988731 0.0033722704947637 2873.8060022502154 0.0001168007900932 0.005931667715914 5078.448280341088 0.0001199956582097 0.0052239204320768 4353.424540533964 0.0002265067490532 0.0077963032923644 3441.9739477741828 0.0004239172201149 0.0135903858220914 3205.905581850982 0.0005876121474936 0.0136264313085717 2318.949900319831 0.0008563684275711 0.0240181792899554 2804.654926160409 0.0019808615363547 0.0331903310551954 1675.5502818371426 0.0014924504006927 0.0297642538842371 1994.321142627025 +r_3555 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane 5.336611396083687e-05 0.0037541925677575 7034.787225677762 0.0001777916204876 0.0052339434573363 2943.86397006826 0.0001172360457373 0.005197745000943 4433.572429240607 4.129766601242436e-05 0.0082666858343168 20017.31969993128 0.0001456596998712 0.0158264207878757 10865.339419114856 0.0003643336749176 0.0106146550576505 2913.443304424129 0.0003174793642862 0.0227233804975017 7157.43542846964 0.0002774107616849 0.0309587841815008 11159.907421564403 -1.0912351384281594e-05 0.0383070801880857 -351043.31632194505 +r_3556 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane 0.0001134634431844 0.0030520495121436 2689.8967865641885 9.160147192124966e-05 0.0057899158803538 6320.767296546852 0.0001009899618682 0.0052492345926419 5197.778566836221 0.0002620150554928 0.0073092250391629 2789.620247361571 0.0005015167082771 0.0162521904348142 3240.6079730914635 0.0002986652809281 0.0120235234786785 4025.751986073427 0.0003950851558188 0.0239050607385738 6050.609694263592 0.0005166313283606 0.0301090731254245 5827.961153839314 0.0011355004202504 0.0341760129644167 3009.775457139785 +r_3557 diglyceride (1-18:1, 2-16:1) transport, cytoplasm-ER membrane 0.0001211773489031 0.0031642241212633 2611.2339887824496 0.0002812912559836 0.0062723438155158 2229.839599379796 0.0001560464067027 0.0052932234188644 3392.0828622129347 0.0003330158311594 0.0073024601861811 2192.826737622987 0.0007529906934701 0.0145788201054635 1936.1222166343207 0.0002829208772094 0.011026489729637 3897.3757745965886 0.0007870552463683 0.0230334782254712 2926.53893506896 0.0019848230953553 0.0389223895283555 1961.0004347206925 0.0005391162524655 0.0376158084800029 6977.309310927498 +r_3558 diglyceride (1-16:0, 2-18:1) transport, cytoplasm-ER membrane 0.000102849992556 0.0031627812219487 3075.1399619450413 4.9533091290880097e-05 0.0053260439857873 10752.496658265292 0.0001059855747929 0.005594919150699 5278.944008778201 0.0004089468610839 0.0070551923953481 1725.2100619252485 0.0002403075828854 0.0136582969838847 5683.672907815333 0.0002667230007472 0.0095990817372499 3598.8953747353994 0.0003910557946981 0.0229441271927172 5867.225982529753 0.0010631677623598 0.0320855676889662 3017.921425471752 0.0002828895141843 0.033892874180143 11980.958105805652 +r_3559 diglyceride (1-16:1, 2-18:1) transport, cytoplasm-ER membrane 2.085231279147542e-05 0.0029489983237945 14142.308113659916 9.820631440627998e-05 0.0051566667072553 5250.850455422004 0.0001435022435115 0.0051268588002411 3572.6680467032297 0.0002022934045301 0.0066745966427671 3299.4633009751547 0.0006947662077919 0.0163398059553081 2351.842356760341 0.0002088639157921 0.0104689566279492 5012.3337907574105 0.0007578458110285 0.0248796071723818 3282.9378760587915 0.0003005096617703 0.0294360609228606 9795.379206594644 0.0011548720950134 0.0374685661587747 3244.390986721232 +r_3560 diglyceride (1-18:0, 2-18:1) transport, cytoplasm-ER membrane 4.530236909417575e-05 0.0032885143759356 7259.034001289076 4.573510351507443e-05 0.0065961958371743 14422.610489993136 -0.0002731095844871 0.0063030872589325 -2307.896762674264 2.5877718812406068e-05 0.0073472254134638 28392.09076629094 -0.0001518104003263 0.0133389272788554 -8786.570123114054 8.796314216193698e-05 0.0122039765986387 13873.966184804583 -8.534261409453325e-05 0.0254692101606956 -29843.484911867905 0.0005881203891664 0.0374247099022206 6363.443708398278 -0.0009524804635303 0.0338627032382695 -3555.2123675857247 +r_3561 diglyceride (1-18:1, 2-18:1) transport, cytoplasm-ER membrane 5.816096991290312e-05 0.0035850380265691 6163.992849393324 -9.57888809407851e-07 0.0057778163745095 -603182.3649846473 -0.0003509295108185 0.0062853140167046 -1791.047439140846 0.0001176553284131 0.0081222418370276 6903.420309621624 -0.0001384519823746 0.014414000074469 -10410.829680617946 -0.0002236401795141 0.0111079695355722 -4966.893498164407 -0.0010026894871455 0.0219617266046986 -2190.281925386394 0.0001144192387882 0.0304324182690582 26597.29132210647 -0.001245721142381 0.031825803216771 -2554.809590526714 +r_3562 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) transport, cytoplasm-ER membrane 0.0003319996141318 0.0043951539313794 1323.8430842375788 0.0005425268665548 0.0073436504084382 1353.6012428419986 0.0004060919203292 0.0059431958195629 1463.5099892516655 0.0005903896385036 0.0090063652747488 1525.4951454728948 0.0012010076228338 0.0170624460392207 1420.6775806269288 0.0010657244493636 0.0143355169677074 1345.1429190976914 0.0010735707759881 0.0190057282288753 1770.3283895169002 0.0025505981306457 0.0368786983976842 1445.8843184499128 0.0023904591638699 0.0369891797833665 1547.367147802874 +r_3563 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) transport, cytoplasm-ER membrane 3.301731942232372e-06 0.0030699649208587 92980.4410100925 0.0001903918779119 0.0070682783223155 3712.489419104486 -0.0003247374081899 0.0057393008491003 -1767.3667105647908 -0.0006905619108764 0.005935583671342 -859.5295480182162 -0.0004222134105717 0.0149081038151314 -3530.940382719002 -0.0007233856288101 0.0134256221881033 -1855.9426194554808 -0.0001365240145728 0.0240943416556943 -17648.427444121568 0.0003167554530622 0.0360463073631156 11379.853768776868 0.0002460924209245 0.0369193924171945 15002.24683006832 +r_3564 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, cytoplasm-ER membrane 0.0002628207417701 0.003615866350983 1375.791852130836 0.0005159226196379 0.0073994277170029 1434.2126968953164 0.0003128095790279 0.0049014637655706 1566.9161349861135 0.00052404897212 0.0077856896882727 1485.6797937748072 0.0012967319188582 0.0160952986104009 1241.2202072246994 0.0009211455883205 0.0142454102240586 1546.4884600957785 0.0017805989789387 0.0269722322389653 1514.784213514501 0.0028289445469589 0.0399771721433988 1413.1479595941153 0.0024236718913244 0.0346568486909135 1429.9315354923922 +r_3565 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, cytoplasm-ER membrane 0.0002747069169109 0.0036959256384326 1345.4068357628237 0.0004135742244421 0.0060449700545289 1461.6409092425909 0.0003524368794278 0.0050983443978242 1446.597871965319 0.0005682325392853 0.0083182271298432 1463.8772957819017 0.0013430643799033 0.0179492992465936 1336.4436966071164 0.0009566164969668 0.0136338081767606 1425.2114844338528 0.0018719906989061 0.0261019430024744 1394.3414899297763 0.0026734677749434 0.0359249859594805 1343.7598274488355 0.0031625478643973 0.0382244820232949 1208.6609803952629 +r_3566 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane 0.0003714810945497 0.0044146419272351 1188.389393701405 0.0004320481621309 0.0060798435085498 1407.2142972585257 0.000406892105371 0.0054870471687708 1348.52632831666 0.0007005976195718 0.0097278110994161 1388.5018772061364 0.0013863153249233 0.0183708673977028 1325.1579252879646 0.0006963021813528 0.0112026582489801 1608.8788099464384 0.0015844040465204 0.0228349533503683 1441.2329607789766 0.0024999148018105 0.0368173344733898 1472.7435689698275 0.0031692632343931 0.0404055399317573 1274.9190251308924 +r_3567 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, cytoplasm-ER membrane 0.0002480440574643 0.0037214501624556 1500.3182097961949 0.0005283005654364 0.0073475863587552 1390.7966107674629 0.0003746922731677 0.0053347038740654 1423.7560409142798 0.0005091719031652 0.0073914275536267 1451.6566031388702 0.0010741711942356 0.0163320240730801 1520.4302778479455 0.0010961480541144 0.0143400812127861 1308.224847816901 0.0018693818827566 0.0247946110017764 1326.3534449800743 0.0031828423071167 0.0408814381215812 1284.4317806814097 0.0024568651986234 0.0363915524323048 1481.2189310465292 +r_3568 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) transport, cytoplasm-ER membrane 0.0002888974989428 0.0037827345806319 1309.3690995851018 0.000428281210631 0.0062597303960916 1461.5935139597595 0.0005463475200089 0.0064973361348818 1189.231376903673 0.0005193965117491 0.0079305668891671 1526.8810455541309 0.0008326357470138 0.013750815671181 1651.4803406528383 0.0009346347302646 0.012812174728474 1370.8215962450372 0.0016658965427481 0.0247403036441077 1485.1044473203312 0.0027434275580227 0.039317213337022 1433.1420278273645 0.0020790204947717 0.0337292654737129 1622.3632984154588 +r_3569 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, cytoplasm-ER membrane 0.00020415079781 0.0030793216602696 1508.3564175609715 0.0005164073203061 0.0069306884587139 1342.0972527278984 0.0003855205029726 0.0056108406559055 1455.393581571289 0.0006101686239784 0.0084924981572594 1391.8280658036747 0.001100959405464 0.0164128273390258 1490.7749784023486 0.0010534920273177 0.0146524049381112 1390.8415591351416 0.0017639328554401 0.0246069005819185 1395.0021116749488 0.0022250140758927 0.0351034167660799 1577.6716716722142 0.0027295269232772 0.0370887968680254 1358.799451719453 +r_3570 sn-glycero-3-phosphocholine transport, ER membrane-cytoplasm 3.218742115699766e-05 0.0006008739517143 1866.7974323992908 5.6258928650870966e-05 0.0010970946742266 1950.0809925388864 0.0001238813159505 0.0013662493767202 1102.8696024392975 7.01515348966604e-05 0.0012423480676517 1770.949230807028 0.0001306238877615 0.0025647724236143 1963.4788609996224 0.0001307219037912 0.002274667988426 1740.0817479359976 0.0002923200340802 0.0047520594073486 1625.635896732264 0.0003269353480611 0.0061678199481747 1886.5564659044344 0.0003046952944286 0.0054462955046288 1787.4563881404051 +r_3571 hexadecanoate (n-C16:0) transport, cytoplasm-lipid particle -0.0001121932012752 0.0034085621637098 -3038.118286105957 -0.0010445543260996 0.0088373256062373 -846.0379116169138 -0.0008982621685026 0.007268358693975 -809.1578326281729 -0.0019726936505639 0.0118131450443594 -598.8332268916804 -0.0026318047705627 0.0212852245412575 -808.7691298130184 -0.0020221657085943 0.0221470524372686 -1095.214518926021 -0.0024140705875399 0.0288753110787073 -1196.125383729281 -0.0053009571741181 0.0468045445149787 -882.9451545751173 -0.0007605147688008 0.0419783102267114 -5519.723212331709 +r_3572 hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle -0.0007585896314075 0.0063409487970417 -835.8865629729786 -0.0012097508283976 0.0132840145758446 -1098.0785682486407 2.6208122473586144e-05 0.0041615752861327 15878.952375649927 -0.0009828446066598 0.0152200444542074 -1548.5707863761384 -0.0044303559690605 0.0330139569818095 -745.1761712233297 -0.0023433440612725 0.0248372620227939 -1059.9067560444548 0.0002634588092694 0.0091855504105587 3486.522404025789 -0.0109870943797108 0.0685026381686636 -623.4827498629954 0.0054573708564116 0.0450384299072807 825.2770627520536 +r_3573 octadecanoate (n-C18:0) transport, cytoplasm-lipid particle -0.0007863365073209 0.0051009432255762 -648.6972406960317 -3.596039572491707e-05 0.0037618857401578 -10461.19116412072 -0.0010078785857666 0.0067137768778573 -666.1295291585724 -0.0018324602666344 0.0119177243429834 -650.3674082315463 -0.0010005351838062 0.007543102791563 -753.9068004453 0.0007141659943278 0.006989707399032 978.7230776243608 -0.0028329953910682 0.0331667316682713 -1170.7301668346352 -0.0020205840087212 0.0215790912345394 -1067.9630810399335 -0.0048256050607747 0.0461670774166955 -956.710647374934 +r_3574 octadecenoate (n-C18:1) transport, cytoplasm-lipid particle -0.0006326256782855 0.0072813459421537 -1150.9722403123094 -0.0012433200331399 0.0125525108179924 -1009.5961203401436 -0.000774352434388 0.0112345495460003 -1450.8315654588191 -0.0029672417910481 0.0204822480415127 -690.2790363530671 0.0019738846144768 0.016933436899865 857.8736961457628 -0.003510856608901 0.0263820349883955 -751.4415405490921 -0.0059471302100155 0.0500706745288912 -841.9300193657674 -0.0177866108840529 0.0828589916768845 -465.8503647323504 -0.0096599978049906 0.0738176770770188 -764.1583214323538 +r_3575 lauroyl-CoA transport, cytoplasm-lipid particle -0.0002246730103589 0.0020731139841568 -922.7249774438905 -8.77014523893374e-05 0.0016998930414175 -1938.2723947045936 -0.0002882710863361 0.0028234544726771 -979.4442129325952 -0.0015403662657418 0.017468182268502 -1134.027838508217 6.401020076388006 79.74994502339257 1245.8943117140511 -0.0003549019320642 0.0059550086683762 -1677.9307550510584 0.0006844222228606 0.0105731557205423 1544.8294002422183 4.597129899514948 67.67177382411968 1472.0439775099646 -0.0066862457670113 0.0589672590355933 -881.9188090052942 +r_3576 myristoyl-CoA transport, cytoplasm-lipid particle -2.084343132533117e-09 2.3957623626791974e-08 -1149.408811478948 -1.622623121015114e-09 9.647508739627522e-09 -594.5625089818783 -0.0001843281330911 0.0023677675158419 -1284.53941139378 -0.0009157351724066 0.0147691686910832 -1612.820948251747 -4.200470386279497 64.67656211265489 -1539.745699051129 -7.273869065965231e-10 8.10687527423999e-09 -1114.520374331789 0.0017319935426983 0.017086739365177 986.5359739481024 0.0002764233630654 0.007359558537116 2662.422761773705 0.0053319151093535 0.0385241464511406 722.5198762740854 +r_3577 palmitoyl-CoA transport, cytoplasm-lipid particle -0.0002445451020208 0.0026733361308924 -1093.1873543164104 0.0001465191623982 0.0026108066569934 1781.8875116809706 0.0003890879766868 0.0034760890597175 893.3941082725615 0.0009824030415597 0.0057287915335888 583.1406552338383 0.000927500418951 0.0089053254525516 960.1424722398112 0.000242558338319 0.0129910841447938 5355.859639715844 0.0003173436665583 0.0118494209344413 3733.939631740648 0.0009524129880153 0.0100068927836269 1050.6883998378726 -0.0023556861745251 0.0395644343902583 -1679.529082358947 +r_3578 palmitoleoyl-CoA transport, cytoplasm-lipid particle 8.90951593097429e-05 0.0015898104393574 1784.395978046815 -0.0002081148517452 0.004032596579164 -1937.678423883111 0.0002324644010226 0.0026721917418441 1149.505786730585 -0.0003592329690118 0.0057676882339946 -1605.5564860485067 -0.0001106887364854 0.006509324122349 -5880.74661345696 -5.762491082059352e-05 0.0066476375518499 -11536.04831172126 -0.0033116416460304 0.0310103290735605 -936.4035239359748 -0.0004168854131965 0.0245014062506074 -5877.251991797169 -0.0078132223054592 0.054284495149861 -694.77730221411 +r_3579 stearoyl-CoA transport, cytoplasm-lipid particle 0.0003868723397444 0.0030697121703942 793.4690219573698 -0.0001709408513688 0.0033083437506566 -1935.3733903650648 0.0003570231976733 0.0021004408819985 588.3205617133139 0.0010049419026386 0.0087424619216639 869.9469987975302 -0.0005937099056779 0.0133399738554018 -2246.8841647789704 -0.0011976963361943 0.0072635320409076 -606.4585672848808 -0.0001775164814069 0.0149769719940443 -8436.947305029718 -0.0001075807260795 0.013257546285409 -12323.347098073367 0.0001980246185238 0.0190940846538639 9642.278215806877 +r_3580 oleoyl-CoA transport, cytoplasm-lipid particle 6.473294040630817e-06 0.0026767759460327 41351.06375875166 0.0003300842510462 0.0046226045577256 1400.4317210147042 1.8248522640240204e-05 0.0035873264865655 19658.174841261043 0.0013129693989045 0.0143602346663132 1093.721961707144 -0.0016944574184882 0.0203566683997048 -1201.367952808566 0.001145143978071 0.0133866425818837 1168.992095162826 0.0007014735451784 0.0111926496181928 1595.5911231613968 0.008915365289768 0.0566709708630608 635.6550631537317 0.0010857044137235 0.0256094819242151 2358.7895195510728 +r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle 0.00018160590778 0.0015788972833695 869.4085465998114 0.0003207404516999 0.0027203798954621 848.1561589888767 0.0003139970988911 0.0022110175653018 704.1522272371697 0.0004793953918167 0.0035159824104064 733.4201518045334 0.0009426919486855 0.0068624255277271 727.960553529282 0.0009259686762627 0.005755766025773 621.5940315609121 0.00127029340029 0.0102407456662149 806.1716815876177 0.0009790970468108 0.0119090350169626 1216.3283563926293 0.0019703730513988 0.0148392360223129 753.1180966862195 +r_3582 dihydroxyacetone phosphate transport, cytoplasm-lipid particle 8.518412860482325e-05 0.0011368302801274 1334.5564470129568 0.0001340110731005 0.0019623002106211 1464.2821411847906 0.0001300641124587 0.0017901707350642 1376.37562062482 0.0001348547787696 0.0022087181653186 1637.8493854421158 0.0002751006036738 0.004377621215512 1591.2801197273984 0.0003824952233237 0.0049375677906569 1290.8835168584271 0.0005903706699503 0.0080068961089131 1356.2489663632578 0.0009211490221597 0.0123895122107523 1345.0062815789536 0.00085597196722 0.0116843692676822 1365.0411129268382 +r_3583 NADPH transport, cytoplasm-lipid particle 8.518412860482325e-05 0.0011368302801274 1334.5564470129568 0.0001340110731005 0.0019623002106211 1464.2821411847906 0.0001300641124587 0.0017901707350642 1376.3756206248197 0.0001348547787696 0.0022087181653186 1637.8493854421158 0.0002751006036738 0.004377621215512 1591.2801197273975 0.0003824952233237 0.0049375677906569 1290.8835168584271 0.0005903706699503 0.0080068961089131 1356.2489663632578 0.0009211490221597 0.0123895122107523 1345.0062815789536 0.00085597196722 0.0116843692676822 1365.0411129268382 +r_3584 NADP(+) transport, cytoplasm-lipid particle -8.518412860482325e-05 0.0011368302801274 -1334.5564470129566 -0.0001340110731005 0.0019623002106211 -1464.2821411847906 -0.0001300641124587 0.0017901707350642 -1376.3756206248197 -0.0001348547787696 0.0022087181653186 -1637.8493854421165 -0.0002751006036738 0.004377621215512 -1591.280119727398 -0.0003824952233237 0.0049375677906569 -1290.8835168584271 -0.0005903706699503 0.0080068961089131 -1356.2489663632578 -0.0009211490221597 0.0123895122107523 -1345.0062815789536 -0.00085597196722 0.0116843692676822 -1365.0411129268382 +r_3585 ATP transport, cytoplasm-lipid particle 0.0026430012501694 0.0104836524359654 396.6571122617926 0.0048968221031097 0.0190692880992804 389.4217044799422 0.0051496842883649 0.0173641362124706 337.18836418191336 0.0064797506274105 0.0248269820598879 383.1471840114545 0.0143918951531168 0.048436397956946 336.55329921199655 0.01035653760679 0.0378425690980284 365.3978823310375 0.0199677783440732 0.0767979877417219 384.60957658074585 0.0185036786051608 0.084911564258862 458.8901810863684 0.0386034776900618 0.1200589977670331 311.00565273149266 +r_3586 AMP transport, cytoplasm-lipid particle -0.0026430012501697 0.0104836524359653 -396.6571122617577 -0.0048968221031119 0.0190692880992826 -389.421704479812 -0.0051496843024753 0.0173641362758905 -337.18836448952845 -0.0064797506216046 0.0248269820552777 -383.1471842836048 -0.01439189515311 0.0484363979569471 -336.5532992121622 -0.0103565376030581 0.0378425690990858 -365.397882472917 -0.0199677783405784 0.0767979877426948 -384.6095766529341 -0.0185036785919718 0.0849115642619608 -458.8901814302012 -0.0386034776795136 0.1200589977699611 -311.00565282405853 +r_3587 diphosphate transport, cytoplasm-lipid particle -0.0026430012501697 0.0104836524359651 -396.6571122617514 -0.004896822103112 0.0190692880992826 -389.4217044798053 -0.0051496844443655 0.0173641362023843 -337.1883537715246 -0.0064797509798138 0.024826982011284 -383.14716242378586 -0.0143918951531175 0.0484363979569473 -336.55329921198904 -0.0103565376103901 0.0378425690970434 -365.397882194511 -0.0199677783654739 0.0767979877370235 -384.6095761450063 -0.0185036787335609 0.0849115643017423 -458.8901781337918 -0.0386034776833781 0.120058997769187 -311.00565279091904 +r_3588 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle -6.498039563357018e-05 0.0032137905749121 -4945.784868770215 -3.629388757480738e-05 0.0056793283177905 -15648.16749400174 -2.659692254948613e-05 0.0049395277454962 -18571.801817694588 -0.0001077374022215 0.0074427620275535 -6908.243445713341 -0.0003613913187266 0.0133946815439371 -3706.420395246833 -0.0004223960846053 0.0131715613432989 -3118.296268206607 -0.0003377881728666 0.0225093946822407 -6663.76045413669 -0.0016435188370249 0.0321974190589517 -1959.0538504100664 -0.0009723652392704 0.0279845241803119 -2877.984840481205 +r_3589 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle -8.174808451323099e-07 0.0036124604208519 -441901.5371873717 -5.988181827272938e-05 0.0048113467881882 -8034.737299183462 -5.36943825241515e-05 0.0050099320642102 -9330.45847385772 5.406474332339233e-05 0.0080058253559077 14807.84863440535 7.690846375792467e-05 0.0151774140454356 19734.38722324203 -0.0001804000097258 0.0099608982878054 -5521.561946113604 -7.489857438151025e-06 0.0217861554418825 -290875.43550442747 0.0001840014191718 0.0293896886139907 15972.533661028194 0.0002558213097098 0.0376685589472371 14724.558712472712 +r_3590 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle -6.67620562484858e-05 0.0028993815672091 -4342.858399114858 3.61869753148902e-06 0.0054812047747529 151468.9947710989 -4.624824955725543e-05 0.0050891373475795 -11003.95668225072 -0.0001429742100103 0.0069304513064216 -4847.343661434273 -0.0003398250555508 0.0158045424994054 -4650.787880777654 -0.000149675110128 0.0115555846824103 -7720.445084372704 -0.000179504365248 0.0232922823982046 -12975.886333469316 -0.0002670536344229 0.0292375318028375 -10948.187193189078 -0.0007745669638776 0.033110537581021 -4274.715954223509 +r_3591 diglyceride (1-18:1, 2-16:1) transport, cytoplasm-lipid particle -6.879925890496735e-05 0.0029947259950582 -4352.846299107554 -0.0001590956128102 0.0059143411403134 -3717.475947854497 -6.402303118938645e-05 0.0050212489216322 -7842.879083276991 -0.0001774217560217 0.0068031698420591 -3834.462015596062 -0.0003890816602873 0.0134100034886434 -3446.5781498768933 -0.0001193402020916 0.0104646603236487 -8768.763702618828 -0.0004918313438506 0.022161810146523 -4505.977592443098 -0.0014854259522572 0.0375865213155731 -2530.353078755476 -0.0003143623066858 0.0370447424607492 -11784.091690666211 +r_3592 diglyceride (1-16:0, 2-18:1) transport, cytoplasm-lipid particle -3.64409375250743e-05 0.0029506710418647 -8097.132626827915 4.81112110999501e-05 0.0049855322117342 10362.516548121986 -4.40200311581982e-05 0.0054218611814268 -12316.804506434602 -0.0002996024656818 0.0066985344378641 -2235.8075133392203 -2.786624002748195e-06 0.0128415052092011 -460826.6201876069 -0.0001882424034705 0.0093036680574168 -4942.386989270124 -3.2866826698697285e-05 0.021870506722248 -66542.79989590519 -0.0006041943207192 0.030569236309344 -5059.504080236258 0.0002381923455192 0.0323188154171886 13568.368600066238 +r_3593 diglyceride (1-16:1, 2-18:1) transport, cytoplasm-lipid particle 1.503549372904522e-05 0.0028252790439927 18790.7300877984 4.154120650836441e-06 0.0047810110345767 115090.80829450728 -5.073387860983796e-05 0.0048416900769397 -9543.307568053444 -0.000133155475408 0.0064463794893918 -4841.242517168064 -0.0004039367105673 0.0155199159082178 -3842.165245743134 2.967611078858964e-05 0.009584180910513 32295.9466582062 -0.0002389936408746 0.0234226949088282 -9800.551522252144 0.0003249045026892 0.0271304447531006 8350.282784183919 -0.000753910464631 0.0363903720982675 -4826.882475504382 +r_3594 diglyceride (1-18:0, 2-18:1) transport, cytoplasm-lipid particle -4.5302031575660266e-05 0.0032885143590159 -7259.088046688906 -4.5734982756385886e-05 0.006596195831437 -14422.648558921876 0.0002731097996685 0.0063030872749207 2307.894950151611 -2.5877508072363247e-05 0.0073472253778294 -28392.321846770825 0.0001518106819392 0.0133389272883843 8786.553830066638 -8.796301456944091e-05 0.0122039766017403 -13873.98631285665 8.534277255085544e-05 0.0254692102332275 29843.429586319733 -0.0005881201335819 0.0374247099029156 -6363.446473933849 0.0009524803628389 0.033862703254248 3555.2127451024044 +r_3595 diglyceride (1-18:1, 2-18:1) transport, cytoplasm-lipid particle -5.8160743550158834e-05 0.0035850380455 -6164.01687232255 9.577210346054213e-07 0.005777816437343 603288.0378077412 0.0003509287646176 0.006285313966964 1791.0512333783818 -0.0001176550344406 0.0081222418423601 -6903.437563018552 0.0001384521472022 0.0144140000509252 10410.817269498424 0.0002236404360102 0.0111079695165308 4966.887793056855 0.0010026890581262 0.0219617265758961 2190.2828596669624 -0.0001144195445427 0.0304324182675727 -26597.220246943463 0.0012457210673138 0.031825803166852 2554.809740472461 +r_3596 H2O transport, cytoplasm-lipid particle 0.0047080731788109 0.0132006852942744 280.3840295789211 0.0081897578395892 0.0233241323952964 284.79636214086474 0.0066825949551142 0.019428452606817 290.7321592482324 0.010494280567575 0.0296271246170794 282.316871807492 0.0207191848500794 0.0591746616174332 285.6032322005482 0.0171638369229035 0.0477490802272548 278.19583955343995 0.0333149235988462 0.0911307128474541 273.5432142807317 0.0491829551259303 0.1358218127234593 276.15626668974005 0.0470378846929467 0.1312655968303062 279.0635626733217 +r_3597 glycerol transport, lipid particle-cytoplasm 0.0003424275951625 0.0023302390645138 680.5056302216627 0.0005856802489645 0.0040711203928972 695.1097292583729 0.0004353110513783 0.003167036057649 727.5340351734271 0.0007721112570666 0.0052522337437047 680.2431250204727 0.0014404042149907 0.0101936891018589 707.6964226965042 0.0012437436797721 0.0084609673049179 680.2822352004104 0.0022972592533745 0.015781706463408 686.9797755836807 0.0032534031029864 0.0232004784933422 713.1141687313568 0.0034963168850957 0.0235265895270207 672.8963735326926 +r_3598 docosanoyl-CoA transport, lipid particle-cytoplasm 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3599 tetracosanoyl-CoA transport, lipid particle-cytoplasm 2.300191837346424e-10 1.475565512582688e-08 6414.967171977047 1.2091125097972948e-10 8.20182800086524e-09 6783.345581496183 2.852066244019611e-10 5.241909078816278e-09 1837.93384526318 5.460923500843597e-10 8.146091547028306e-10 149.17058526401095 1.1818083970324995e-09 8.157722565142467e-09 690.2745475177167 -1.3165143483014342e-09 8.419046847566383e-09 -639.4952594651648 7.15836370185962e-11 3.2228159284115197e-09 4502.168460055037 3.1310849052031776e-10 4.615329352405041e-09 1474.0351961505014 6.390693908166992e-10 6.829557481780378e-09 1068.6722881614685 +r_3600 hexacosanoyl-CoA transport, lipid particle-cytoplasm 3.2812242752254e-10 2.3027896029888707e-09 701.8080477996839 0.0001529452646787 0.0033253428456951 2174.2045121047736 0.0006487689791741 0.0071253183901941 1098.2828431877915 0.0012846069219233 0.0181120356358087 1409.928229928203 2.2003112032163368 46.85695995469331 2129.560576985631 4.5662555868608737e-10 1.0118748574521453e-08 2215.9838366554736 5.763343322938689e-10 2.35477515692031e-09 408.5779772216704 4.60282228485792 67.67360156638523 1470.2631858938737 3.503634200756923e-09 1.2566957011274932e-08 358.6834781028217 +r_3601 ATP transport, cytoplasm-cell envelope 0.0045093080512799 0.0176638491689649 391.7197265764768 0.007766325132996 0.0313098660322001 403.1490504972143 0.0069084319903843 0.0270860959216253 392.0729907933608 0.0095363588438034 0.0386908250821207 405.7190560447662 0.0186420682235762 0.0766365204779247 411.0945178336182 0.0165119843611387 0.0650187570327953 393.7670700913348 0.0306286483446637 0.1202030682766436 392.453061996077 0.0441578404623964 0.1779985427341114 403.0961226142607 0.0420887078431642 0.1703632115137877 404.77177904490367 +r_3602 ADP transport, cytoplasm-cell envelope -0.0045093080512799 0.0176638491689649 -391.7197265764769 -0.0077663251329959 0.0313098660322002 -403.1490504972189 -0.0069084319903843 0.0270860959216253 -392.0729907933608 -0.0095363588438034 0.0386908250821207 -405.7190560447662 -0.0186420682235762 0.0766365204779247 -411.0945178336182 -0.0165119843611387 0.0650187570327952 -393.7670700913348 -0.0306286483446637 0.1202030682766437 -392.45306199607694 -0.0441578404623964 0.1779985427341114 -403.0961226142607 -0.0420887078431642 0.1703632115137877 -404.77177904490367 +r_3603 H+ transport, cytoplasm-cell envelope 0.0009869017563715 0.0228140674166456 2311.6857650069915 0.0017679042878232 0.0417934510690726 2364.0109567544728 0.0014835262233879 0.0352347550889676 2375.067897923758 0.0023118134194132 0.0514910858528442 2227.3028359664304 0.0036636304337125 0.0989329136834041 2700.40648131504 0.002725931298834 0.0864657150851117 3171.969708924625 0.0071820420373126 0.1536665634621923 2139.594319607902 0.0087830346080402 0.2365942135690881 2693.763876923618 0.0062189980868335 0.2266164094032508 3643.9375963634616 +r_3604 H2O transport, cytoplasm-cell envelope 0.0026528401356703 0.0110183505127357 415.3416696536597 0.0046453827341064 0.0200891533496169 432.4542131291433 0.0042327506308338 0.0171590075917886 405.3866879563467 0.0056897254965639 0.0244127329975697 429.0669736582694 0.0119411079249873 0.05010998162868 419.642649103126 0.0107390006975584 0.0431310514020652 401.63002700866855 0.0185466724656646 0.0756186331654781 407.7207558685834 0.0281445726912316 0.1168691694291547 415.24584761439576 0.0281117862526236 0.1146172668946782 407.7196157678568 +r_3605 phosphate transport, cytoplasm-cell envelope -0.0017887248814312 0.0102137862029418 -571.0093435257296 -0.0031181730640763 0.0185123348036892 -593.6917041893778 -0.0027912440884328 0.0158438610730652 -567.6272146432209 -0.0036409989611407 0.0224202065777226 -615.770749099539 -0.0078453333043188 0.0464545107543792 -592.1292181277494 -0.0071895518725616 0.0401596011378465 -558.5828136397787 -0.0120004377929006 0.0696142219310894 -580.0973525505243 -0.0186036439772809 0.10841748856923 -582.7755503256856 -0.0187648557574507 0.1066237800827906 -568.2099636734746 +r_3606 sn-glycero-3-phosphocholine transport, cell envelope-cytoplasm 8.105771334055781e-05 0.0009941910966203 1226.5225055675578 0.0001083998827912 0.0015365896344281 1417.5196456504093 8.734392632460228e-05 0.0012687848634788 1452.6309004744849 0.0001561500601683 0.0020810776031219 1332.742107737678 0.0003354536976188 0.0043076904617822 1284.1386135732157 0.0002494502097773 0.0033345067165515 1336.742398223449 0.0004337012387984 0.0060001100888207 1383.466209468124 0.0006581324581731 0.0091047130517779 1383.4165050985694 0.0006317719554106 0.0087241410154095 1380.9003297304116 +r_3607 1-(sn-glycero-3-phospho)-1D-myo-inositol transport, cell envelope-cytoplasm 4.381675829799332e-05 0.0005637492362709 1286.6064450432268 4.281792997193235e-05 0.00059784023124 1396.2380517507138 8.438422920466577e-05 0.0010103394498496 1197.3083825879348 0.000110437387846 0.0014004420594812 1268.086910416136 0.0002181280113576 0.0028109958712826 1288.690917680146 0.0001936415818588 0.0023207444977355 1198.4742509629243 0.0004072184039213 0.0046852959901513 1150.560963118019 0.0005387302455927 0.0067317678412796 1249.5618904546036 0.0005209376560945 0.0064927745101359 1246.363059797276 +r_3608 palmitate transport, cell envelope-cytoplasm 3.93840019149504e-05 0.0006370328235238 1617.491348135535 3.942069573537183e-05 0.000875816480366 2221.717460912695 4.7219817576212544e-05 0.0008514348307086 1803.1302838779627 9.8554105121665e-05 0.0015186695772911 1540.9500958040887 0.0001185539043942 0.0024508296305504 2067.2702793489007 0.000126708072384 0.0021590566056959 1703.9613696845684 0.0001480868737261 0.0032339276259397 2183.804374126588 0.0003133887538678 0.0058114373773716 1854.386063841219 0.0004910352599949 0.007063027730023 1438.3952244275 +r_3609 palmitoleate transport, cell envelope-cytoplasm 0.0001372614627229 0.0018516327146225 1348.9822109501692 0.0003031195322711 0.0042171484985248 1391.249342108665 0.0003236795894981 0.0039428390451871 1218.1302661993172 0.0003964542117279 0.0051129369084009 1289.666437422005 0.0008824208875531 0.0103066448318574 1167.996471665172 0.0006457147280713 0.0082996200215702 1285.3385033295312 0.0014729029564223 0.0174191000051734 1182.6373169542971 0.0017836552988569 0.0236566210044883 1326.300043492068 0.0009321734867708 0.0154916546606969 1661.88535509218 +r_3610 stearate transport, cell envelope-cytoplasm 3.495595954773239e-05 0.0006033023267094 1725.8926217878725 4.761568041208535e-05 0.0008925562806522 1874.500737840285 4.031341745025003e-05 0.0007888257395596 1956.732496154988 5.814269049860797e-05 0.0011628438577344 1999.98288308022 9.953869205659204e-05 0.0022056620373112 2215.884086619537 0.0001040316778999 0.0019284539779373 1853.718037492826 0.0002501473677447 0.0041572909991518 1661.9367361859556 0.0004263967536064 0.0067365791867728 1579.8851960751608 0.0003658458569403 0.0061891921506069 1691.7485966269548 +r_3611 oleate transport, cell envelope-cytoplasm 0.000171026089808 0.002190342404803 1280.706591176781 0.0002330773201204 0.0036006547509284 1544.832740082869 0.0001885571271388 0.0026054319980463 1381.7732787836812 0.0003872673174945 0.0050392191622884 1301.2250026390077 0.0004821954112637 0.0074766311317526 1550.5396685873438 0.0005049238018038 0.0064802741938165 1283.4162641305004 0.0009212362973024 0.0125283691712612 1359.951752655254 0.001061417377744 0.0143606335949438 1352.9676351697524 0.0017939409365462 0.0219300592002372 1222.451573152548 +r_3612 icosanoyl-CoA transport, cell envelope-cytoplasm 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3613 docosanoyl-CoA transport, cell envelope-cytoplasm 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3614 tetracosanoyl-CoA transport, cell envelope-cytoplasm 1.1628777033637863e-10 2.2227184503610933e-08 19113.94847395877 -8.445258431099651e-11 1.1828958670753317e-08 -14006.627230249336 3.856622415333981e-09 1.96697558068876e-08 510.0254494368023 2.693182220901141e-09 1.1719443525227452e-08 435.1522683565806 2.333665624229303e-09 1.3296514394047472e-08 569.7694757979164 6.938857321375879e-11 9.953492738085407e-10 1434.4570405594916 1.1114322901887174e-09 2.1762931889168752e-08 1958.0978599671128 4.293999792479327e-09 2.1625714535238312e-08 503.62635259355153 2.1612247123683958e-10 1.8959507803748472e-08 8772.575889608232 +r_3615 hexacosanoyl-CoA transport, cell envelope-cytoplasm -7.3226380365434e-10 1.5011235024847457e-08 -2049.9763814535618 2.590109936786481e-09 1.4072812760064558e-08 543.3287815390776 1.788642136664719e-09 1.2304445185259809e-08 687.9210174598652 8.765327808118372e-10 1.0056547773173797e-08 1147.309945882401 4.0953784765103134e-09 1.8330014595167264e-08 447.578037055719 1.225608923553293e-09 1.2898950354967115e-08 1052.4523856737594 4.960009981808269e-09 2.119020382273822e-08 427.2209914991524 3.297976355574361e-09 1.8176285720101065e-08 551.1345067522644 2.9449109691149104e-09 2.0060804885417933e-08 681.2024232925173 +r_3616 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-16:1) transport, cell envelope-cytoplasm 8.78132610163751e-05 0.0028385874012584 3232.5270333932467 0.0001651343790476 0.0047168216727164 2856.353534569896 0.0001473698260043 0.0044640721486909 3029.1629363522097 9.645779200554848e-05 0.0053041255037989 5498.908272225268 0.000635994998023 0.0155130057308972 2439.171027935578 0.0006664396670915 0.0141957073681285 2130.081396577336 0.0007546554237313 0.0197954325035466 2623.108756797776 0.0015085728876769 0.0360542269270208 2389.955912739485 0.0013937336277317 0.0323731847931711 2322.7670014576165 +r_3617 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-16:1) transport, cell envelope-cytoplasm 4.448593000234889e-05 0.0022130900316942 4974.808959995661 0.0001596430205924 0.0053495056680811 3350.917345605952 0.0002846890477556 0.0060516555449076 2125.7071856525104 0.0002524675407548 0.0072105812636626 2856.042896486106 0.0004343897768036 0.0147422943413554 3393.79403673666 0.0004640751291009 0.0132235081060039 2849.4326191585915 0.0007374802978377 0.0216612980177443 2937.203621744776 0.0011967741482193 0.0324571019111265 2712.049049473359 0.0012142827721367 0.0360251090517498 2966.7808749651945 +r_3618 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-16:1) transport, cell envelope-cytoplasm 0.0001138307848836 0.0029020646600042 2549.4550204232023 0.0003493100008158 0.0068403181596321 1958.2371371151096 0.0003687447689304 0.0069957946705464 1897.1915698864584 0.0002575185676258 0.0063601801123485 2469.794768969954 0.0003694204895847 0.012714485799916 3441.738116423708 0.0005742038086642 0.0123684584762412 2154.0188848647617 0.0013587286780243 0.0263575036200598 1939.8651140847687 0.0017564046842577 0.0414604152550982 2360.5274813201854 0.0010248897374801 0.0281195901365438 2743.669792779973 +r_3619 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-16:1) transport, cell envelope-cytoplasm 0.0001177947185453 0.0031241435070099 2652.193193030822 0.0003101795984059 0.0066341938471847 2138.823404659635 7.853035257708864e-05 0.0042986282505957 5473.843054984409 0.0001773529498735 0.0063137642994253 3559.999596243645 0.0009536100826595 0.0180416477805583 1891.9313153905464 0.0002138567373479 0.0112260822993239 5249.34703415881 0.0010301934908365 0.0266514260343435 2587.0311035165523 0.0007638987891226 0.0295802451693014 3872.272818140789 0.0008836954539378 0.0292947047919139 3315.0226881187264 +r_3620 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-18:1) transport, cell envelope-cytoplasm 0.0001105120336785 0.0034172020417156 3092.153793544769 0.0001407343431306 0.0055577523958786 3949.108847382588 0.0002149350047 0.0051024179662983 2373.935308219596 0.0004974082363108 0.0092831345145112 1866.300924842196 0.0002671081051459 0.0111043871827261 4157.263283590911 0.000408681235653 0.0113988278263392 2789.17328027695 0.0012061516207294 0.0260952162057143 2163.5104374301386 0.0012987167694524 0.0328364994647171 2528.38033950713 0.0020176498891354 0.0385169192031337 1908.9991484914613 +r_3621 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-18:1) transport, cell envelope-cytoplasm 0.0002058089921398 0.004089892411947 1987.2272680721785 0.0002943973380434 0.0069537513381637 2362.0292847676287 0.0003629030959431 0.0063851099435728 1759.4531473969955 0.000452868017826 0.0101241474474569 2235.5624705090404 0.0001339419377394 0.0066965697522067 4999.606445319587 0.0006969255737616 0.0135548454074753 1944.9487747038247 0.0013827008100665 0.0268946729825268 1945.082608379455 0.0019083990116789 0.0392462955321394 2056.5036605008754 7.337882142157796e-05 0.0155692618872858 21217.650523216987 +r_3622 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) transport, cell envelope-cytoplasm 0.0001548910835769 0.0039370843343925 2541.8405265644847 0.0001209452951545 0.0051161685950729 4230.1509856457305 0.0001059982415825 0.0039854377800158 3759.909334828745 0.0002513690733172 0.0068063943542492 2707.7294212958373 0.0006697055792884 0.0153288802131778 2288.898388671741 0.0005473366778531 0.0128182099864806 2341.9241766799114 0.0010065489981001 0.0224822826911504 2233.6004241805813 0.0009921427214773 0.0298132902987981 3004.9396778726364 0.0009531815756038 0.0279093575784638 2928.0210919711235 +r_3623 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) transport, cell envelope-cytoplasm 0.0001437882269319 0.0033485389589672 2328.799116879155 0.000209078201458 0.0059170289376468 2830.0554033764934 3.287151296282054e-05 0.0020937391085101 6369.463769064303 0.0003950821826527 0.0086495793671091 2189.3114260514794 0.0002173759918672 0.0121286750947802 5579.583555017589 0.0001357059798153 0.0073530522324096 5418.370098662311 0.0003010754432437 0.0148788504051176 4941.901021489246 0.0005006005315702 0.0206101323664619 4117.081598338169 0.0012464633704461 0.0313233906029735 2512.981235201607 +r_3624 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-16:1) transport, cell envelope-cytoplasm 8.088593016048762e-05 0.004905155411478 6064.28757355657 0.0001138519193533 0.0076634518519384 6731.069529140961 9.605932722781778e-05 0.0066188581482062 6890.38570144129 0.0002584745346111 0.009539821463294 3690.816767557305 5.026667712939569e-05 0.0213155987574176 42405.02848944522 -0.0001535184138796 0.0186587585601451 -12154.085030332535 -0.0003888211221043 0.0238164271654068 -6125.291505901403 -0.0002490715148549 0.0474162514382482 -19037.203618351352 6.565044787841283e-05 0.0460666472923807 70169.58570899312 +r_3625 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-16:1) transport, cell envelope-cytoplasm 3.5863563880028884e-05 0.0034109365503776 9510.86891918471 7.999595388444684e-05 0.0082472403785274 10309.571894649238 -8.386662969537105e-05 0.0079525373525175 -9482.361913675946 -0.0001882536273209 0.008560271104751 -4547.201149094708 -1.971706760210732e-05 0.0184320071930264 -93482.49732154122 -0.0001044284509921 0.0167636673348622 -16052.777931297243 -4.800471162853037e-06 0.0288372092023116 -600716.2260542152 -4.344195619550627e-07 0.0430577132058317 -9911550.256175091 2.098714142160412e-05 0.0463057481127681 220638.6624197477 +r_3626 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-16:1) transport, cell envelope-cytoplasm 1.2826902715097931e-05 0.0042591078618626 33204.491812739005 -1.3490443263414409e-05 0.0094510084985133 -70057.06420443713 -0.0002259029133081 0.0079954978934557 -3539.351386118484 -9.305563199419516e-06 0.0087558842452838 -94093.00713609776 -5.203873994116842e-05 0.0173839177767004 -33405.72388254128 -4.956395617846888e-06 0.0176891419466847 -356895.2785566596 -0.00025733363468 0.0360792851973999 -14020.43119713454 -0.0004160708606378 0.053519030531832 -12862.960518259682 0.0002691131616088 0.03994295929762 14842.439908485789 +r_3627 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-16:1) transport, cell envelope-cytoplasm 1.3884310300670044e-05 0.0042281805811094 30452.939249747164 -0.0001634613536833 0.0081545025512185 -4988.642494064002 3.774184020580804e-05 0.0056942175214127 15087.281092712854 6.449879289357297e-05 0.0093666050296222 14522.140042338116 -0.00033921773437 0.0229217387172482 -6757.234777190257 0.0001879334248972 0.015871924132524 8445.503582557494 -7.802621757876291e-05 0.034475209895178 -44184.13574947078 -2.6815820255222496e-05 0.0394517076950969 -147121.0178156441 -0.0001735055758346 0.0406368095776588 -23421.03957304071 +r_3628 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-18:1) transport, cell envelope-cytoplasm 0.0001007756043994 0.0050919120482127 5052.722907056028 2.3333354604247e-05 0.0069502902367461 29786.931003401827 -6.0764589452681486e-05 0.0068279366621152 -11236.703355713957 -3.110733860935662e-05 0.0127214728517051 -40895.40738749914 0.0004543779078765 0.0188057494471117 4138.790447581094 -0.0002496315035725 0.0142703796537899 -5716.578015820799 -0.0008199998161558 0.0320631388050962 -3910.1397553243737 -0.0004650831400258 0.0444927455291123 -9566.62190047186 -0.0006683017503461 0.0505232438690716 -7559.944866657318 +r_3629 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-18:1) transport, cell envelope-cytoplasm -9.582495405633623e-05 0.0051745082211661 -5399.958989934975 1.936749622441368e-05 0.0094903437133815 49001.3969974007 -0.0002278613801694 0.0077581903890271 -3404.7851300027246 -0.0002898110163252 0.0115982041153499 -4001.988696777122 0.0004308496715087 0.0151086936127084 3506.720466978684 -0.000196601466584 0.0175900893865044 -8947.07943543427 -0.0007627711922151 0.032738094750732 -4291.9941241696 -0.0006174346836727 0.0505827599032308 -8192.40662062378 0.0012247626255265 0.0337755643867222 2757.723307583796 +r_3630 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-18:1) transport, cell envelope-cytoplasm -1.7967773659367374e-05 0.0048168151288322 -26808.079955532103 -1.6982282663372883e-05 0.0071425436792569 -42058.79633991632 0.0001885633150377 0.0065905799708655 3495.154913641168 -1.767925355521998e-05 0.0095380495309313 -53950.521729550834 -0.0003556837373879 0.0186444934991994 -5241.874041281409 -0.000313523304916 0.0159585656975377 -5090.073193063574 -2.49144032590935e-05 0.0315447484998646 -126612.4986892917 0.0003621366278253 0.0447082681238426 12345.69073896691 0.0002052459405017 0.0390356002184663 19018.938997303205 +r_3631 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-18:1) transport, cell envelope-cytoplasm -0.0001044134662329 0.0041651908747714 -3989.1318859958737 -4.93207068492077e-05 0.0082295925547868 -16685.87715084426 0.000157999159361 0.0051673736213803 3270.5070345165445 -0.0001265395887554 0.0109985633170163 -8691.796318595498 0.0002504699012407 0.0181904892555619 7262.544986623554 0.0005045096044748 0.014468292531942 2867.793279575315 0.0005366276354526 0.0242283474510778 4514.927269938628 0.000859142494776 0.0361623876623538 4209.125713398536 -0.0001162473309417 0.0424957383356503 -36556.31315693329 +r_3632 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-16:1) transport, nucleus-cytoplasm 0.0001107327260853 0.0020188609527374 1823.1836459815904 7.938552775146181e-05 0.0022913941755105 2886.4129777967064 0.0001277488758826 0.0026676143454718 2088.170504076895 0.0002452046423657 0.004459300394028 1818.6035757739112 0.0004371794548849 0.0085225126063821 1949.431180068759 0.0004897578244186 0.008149613327685 1664.0088062624802 0.0003469797133616 0.0092674486907922 2670.8906411286025 0.0008397517705391 0.0178807181882198 2129.2861552099566 0.0008072765251187 0.0171939733011287 2129.8740600191627 +r_3633 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-16:1) transport, nucleus-cytoplasm 8.135705295920141e-05 0.001729494360553 2125.8075331468985 0.0001886376339127 0.0035507010631395 1882.2866834632875 0.000114243965869 0.0025326759159102 2216.901257447877 0.0001688189073692 0.0037471973604988 2219.655024957502 0.0004380981172922 0.008527270590927 1946.4294080127395 0.0004666538571201 0.0079590701429522 1705.5618466478406 0.0005069277260106 0.011243001442124 2217.87068752422 0.0010229970142834 0.0195222044599001 1908.3344513546467 0.0011872366965791 0.0207358995532224 1746.5682801896637 +r_3634 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-16:1) transport, nucleus-cytoplasm 8.608539547775355e-05 0.0017634259729855 2048.461255476502 0.000134314164394 0.0030006558525579 2234.057640976474 0.0001353244335067 0.0027599666111835 2039.5183188011445 0.0001188171765996 0.0031338668995135 2637.553752073858 0.000767507620988 0.011292126714246 1471.2722591222682 0.000326085758801 0.0066502894997359 2039.429604098222 0.0005511189191345 0.0117394129763323 2130.105240220484 0.001371452406711 0.0228078323292705 1663.0422038463098 0.0009536428007733 0.0186800280624747 1958.8076423716643 +r_3635 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-16:1) transport, nucleus-cytoplasm 5.517106678898967e-05 0.0014015118096314 2540.302175036266 0.0002004065526143 0.0036544992614666 1823.5428002689853 0.0001929776150237 0.0033042451315839 1712.2427029569403 0.0001795540543641 0.0038380775229813 2137.5610462118298 0.0005663063162203 0.0096971745407002 1712.3550034583927 0.0005104846072268 0.0082788539737465 1621.7636842608056 0.0008024890025836 0.0140675836560017 1752.9939489152714 0.0015261619345508 0.0240849808153414 1578.1405806343876 0.0017525789815032 0.0252402258760312 1440.1762284277584 +r_3636 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-18:1) transport, nucleus-cytoplasm 0.000110072724943 0.0020072571607514 1823.57360716744 0.0001891713638162 0.0035451087172465 1874.0197489353832 0.0002156905031636 0.0034926620555701 1619.2933876742145 0.0001733701288507 0.0037524586495615 2164.420522978992 0.0004351410246893 0.0085235811715606 1958.8089120406569 0.0004102479980615 0.0074795875699899 1823.1868541302688 0.001005902297306 0.0158745259421322 1578.1379548138814 0.0011407516600658 0.0208004154866721 1823.3955921195563 0.0013929247616975 0.0225556427549448 1619.300867870067 +r_3637 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-18:1) transport, nucleus-cytoplasm 0.0001318345969724 0.0021669372825685 1643.6787704677652 0.0001881350010608 0.0035507815584961 1887.358300408846 0.0001917343296418 0.003283447793428 1712.4986430761066 0.0003073330195579 0.0050375126746744 1639.105580624184 0.000331118091032 0.0074016393269799 2235.3473058237737 0.000355463736883 0.0069628585607757 1958.809813296646 0.0009558289403556 0.0154776713474624 1619.293023467479 0.0012919813739087 0.0221251713072567 1712.4992475951244 0.0008066640183335 0.0171809709717652 2129.879427033266 +r_3638 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) transport, nucleus-cytoplasm 0.0001316489861298 0.002191169418657 1664.4028055753292 0.0002543895528051 0.0041196796685535 1619.437442743402 0.0001797649009596 0.0031751740980763 1766.2925749832325 0.0002342538951845 0.0044212988012756 1887.396065620537 0.0003650351303707 0.0077770071861542 2130.48184657044 0.0004919854502345 0.0081858425160179 1663.8383334537946 0.0006037388331728 0.0123102200433142 2038.9975543929647 0.0009928694165192 0.0194484025826092 1958.8077000892144 0.0005795398299394 0.0144865529857361 2499.664774938774 +r_3639 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) transport, nucleus-cytoplasm 0.0001535514753314 0.0023665762352963 1541.2266343829835 0.000257521996716 0.004127376370914 1602.727698428169 0.000100766663703 0.0023743298124711 2356.265182569071 0.0003017776234019 0.005021059118851 1663.8275105518908 0.0004687075345576 0.0088462135420371 1887.3632040896389 0.0002462434706599 0.0057993738364682 2355.1381163225046 0.000552863952522 0.0117753637187989 2129.884515906885 0.0005659742597214 0.0144515861002299 2553.3998855957934 0.0011673157288789 0.0206084785930787 1765.4588285955724 +r_3640 diglyceride (1-16:0, 2-16:1) transport, nucleus-cytoplasm -7.658642346243793e-12 1.689905984575808e-09 -22065.346678639824 -2.2496620713168025e-11 1.5825277413920604e-09 -7034.51314563771 2.3582080612934166e-10 1.66122778968149e-09 704.4449626596343 6.273497717195919e-11 1.3510729774887731e-09 2153.619939615863 6.112173154142851e-11 1.3866321404731134e-09 2268.640147298919 -5.7650312341732204e-11 1.425822434887504e-09 -2473.2258629158755 -6.931712071806576e-12 1.354652684362118e-09 -19542.82968376472 -9.09451936424888e-12 1.4916837173752552e-09 -16402.00716091888 -7.894692047339689e-11 1.576543256926684e-09 -1996.9661229001824 +r_3641 diglyceride (1-16:1, 2-16:1) transport, nucleus-cytoplasm -3.961914655780759e-11 1.979991238224436e-09 -4997.561558615269 2.429578385227077e-12 1.5273045116418163e-09 62862.94448981401 1.1550225947763679e-10 1.2271783476249415e-09 1062.4712911893678 1.3831523597320132e-10 1.849609379346271e-09 1337.2419649449423 -4.400728476763717e-11 1.5928674119949102e-09 -3619.553945228405 1.2658503781012515e-11 1.3760106443125368e-09 10870.247132812989 5.924200035137257e-11 1.29359177873697e-09 2183.572079039359 1.6384122432520322e-10 1.19878484478226e-09 731.6747355371504 1.3141532363454536e-10 1.248277351387193e-09 949.8719912287736 +r_3642 diglyceride (1-18:0, 2-16:1) transport, nucleus-cytoplasm 9.052093135344514e-11 1.3649707429955604e-09 1507.906207533305 -7.912186766164469e-11 1.5934926955692255e-09 -2013.9725497679208 -3.2250230886334795e-11 1.7169486981217774e-09 -5323.833817417073 -1.6394624243143374e-11 1.473197564056456e-09 -8985.857450637106 -9.685943399660148e-11 1.504681796922292e-09 -1553.469532947185 -4.7423807224034175e-11 1.553815852842027e-09 -3276.4468814190022 -1.2031962810064562e-10 1.4558946579907627e-09 -1210.0225715233494 3.5433690503846844e-11 1.3255911598934715e-09 3741.0474072678353 2.7336343383853304e-11 1.140788895749386e-09 4173.158347225083 +r_3643 diglyceride (1-18:1, 2-16:1) transport, nucleus-cytoplasm -2.116110371633466e-10 1.940320737594813e-09 -916.927946483738 5.2543625303233393e-11 1.463092682666567e-09 2784.529377679869 6.956048993063602e-11 1.6957207488731644e-09 2437.7642402520382 1.6323657945708315e-10 1.340260943286416e-09 821.0542929434433 2.7515425470683502e-11 1.4379414538088155e-09 5225.946643423268 -1.6519683353736867e-10 1.680147255388934e-09 -1017.0577845905706 4.1308025002301405e-11 1.4582797229175531e-09 3530.2576747164926 9.461815997247624e-11 1.432284812178946e-09 1513.75255299362 1.3730819415297149e-10 1.1773733730018492e-09 857.4676699120868 +r_3644 diglyceride (1-16:0, 2-18:1) transport, nucleus-cytoplasm 4.997006103201125e-12 1.476264968250041e-09 29542.989097098216 5.783981086828326e-11 1.3466642001956184e-09 2328.265220753113 1.2542781612801716e-11 1.860948595162593e-09 14836.80935067248 2.0485938917751328e-10 1.3079642883224231e-09 638.4692903624031 8.737329683706604e-11 1.4156555777414539e-09 1620.2382524049335 7.355441016503548e-11 1.324870675942721e-09 1801.2117464745932 3.817599267793841e-11 1.383158520762357e-09 3623.110818442904 1.061474123417426e-10 1.2768554116665728e-09 1202.9077143734078 7.895587831983818e-11 1.322349938133257e-09 1674.7960585994874 +r_3645 diglyceride (1-16:1, 2-18:1) transport, nucleus-cytoplasm -2.4112170529606074e-11 1.931155284836465e-09 -8009.047889178209 4.394102454337185e-11 1.331537568355788e-09 3030.283390505604 8.948512001673922e-11 1.604317273527573e-09 1792.831336905473 1.1027716525177283e-10 1.3665928286464012e-09 1239.2346371312185 7.5592470828398e-11 1.37094302800167e-09 1813.597323884067 9.655795365853495e-11 1.3807112384470276e-09 1429.9300949663236 7.642937687605563e-11 1.2699362680610568e-09 1661.5813447236303 1.0694960843199627e-10 1.2947001062824342e-09 1210.570216445128 3.486919408820887e-11 1.8178414269205281e-09 5213.316437202194 +r_3646 diglyceride (1-18:0, 2-18:1) transport, nucleus-cytoplasm 2.0763577049680007e-10 1.357571765249245e-09 653.8236460900009 1.2003204846713747e-10 1.502395438181098e-09 1251.6619164359474 1.9773742166453032e-10 1.0900891074342012e-09 551.2811375095114 3.0631287332110205e-10 1.2701695028911882e-09 414.6640946297066 2.1807916339737188e-10 1.3415487762873588e-09 615.1659587224581 5.584089343985917e-11 1.363070601313778e-09 2440.989957980901 1.0215203923021658e-10 1.3252341496382684e-09 1297.3154130106336 2.456187824081988e-10 1.08714858839501e-09 442.61622736499663 -1.3565144263287747e-10 2.296291993698153e-09 -1692.7884798931043 +r_3647 diglyceride (1-18:1, 2-18:1) transport, nucleus-cytoplasm 1.0153132284792807e-10 1.6626994807777684e-09 1637.6221978986052 -2.0013780047733772e-10 1.9161297304306955e-09 -957.4052107401194 -7.684302518298108e-10 2.4224237383865926e-09 -315.2431509064407 1.3029503185724908e-10 2.105981776551901e-09 1616.3177878180416 7.334417547617076e-11 1.6902082434665271e-09 2304.488710239396 1.4033695950621712e-10 1.528936860325588e-09 1089.4755492104373 -3.789125135484037e-10 2.244071448346909e-09 -592.2399942223714 -3.0196529463179944e-10 2.056462223883823e-09 -681.0260186990578 -6.729072880960622e-11 1.8294920104830358e-09 -2718.7876292132887 +r_3648 H2O transport, cytoplasm-vacuolar membrane 0.0012715311915339 0.0095434994567754 750.5517379610769 0.0025980126717732 0.0183336917225912 705.6813818416672 0.0019032118413858 0.0144740218198495 760.505031815603 0.002780867079544 0.0212714766608798 764.9224523297939 0.0052918595759938 0.0413371362838993 781.1457520797103 0.0044652175166788 0.0343317980030034 768.871793473988 0.0077431278365392 0.0614271042286645 793.3112499937662 0.0129549625034233 0.0979985655451332 756.4558023169649 0.0111837047727633 0.0895235111591217 800.4817095775447 +r_3649 phosphate transport, cytoplasm-vacuolar membrane -0.0012715311915339 0.0095434994567754 -750.5517379610769 -0.0025980126717732 0.0183336917225912 -705.6813818416672 -0.0019032118413858 0.0144740218198495 -760.505031815603 -0.002780867079544 0.0212714766608799 -764.9224523297942 -0.0052918595759938 0.0413371362838993 -781.1457520797103 -0.0044652175166788 0.0343317980030034 -768.871793473988 -0.0077431278365392 0.0614271042286645 -793.3112499937662 -0.0129549625034233 0.0979985655451332 -756.4558023169649 -0.0111837047727633 0.0895235111591217 -800.4817095775447 +r_3650 H+ transport, cytoplasm-vacuolar membrane 0.0016120313325018 0.0172925771859259 1072.7196697280276 0.0030203895937114 0.0327705329123384 1084.9770168910743 0.0023071811996178 0.0260005891342919 1126.9417910738428 0.0036786625795659 0.0388509491537053 1056.1161376830837 0.0079620198997106 0.077577672728667 974.3466319581332 0.0063128828666588 0.0636441912310159 1008.1636642927332 0.0118705544269148 0.1157861456034202 975.4063832173769 0.016850587717377 0.1787745017816031 1060.9392668081443 0.0191926775126112 0.1730342880666654 901.5640884549164 +r_3651 ATP transport, cytoplasm-vacuolar membrane 0.0041550937155697 0.0169597920280011 408.1687006107779 0.0082164149372584 0.032149206002597 391.2802146446133 0.0061136048823894 0.0255790215540446 418.3950720748476 0.0092403967386546 0.0382105205509175 413.5160170241864 0.0185457390516984 0.0764843005359449 412.4090192509224 0.0152433179000173 0.0625934293811475 410.6286426072384 0.0273568100999926 0.1140243481847434 416.804253741462 0.0427605127242254 0.1754016572925562 410.1954025288953 0.0415600870581402 0.1693796047810127 407.5535369886501 +r_3652 ADP transport, cytoplasm-vacuolar membrane -0.0041550937155697 0.0169597920280011 -408.1687006107779 -0.0082164149372584 0.032149206002597 -391.2802146446133 -0.0061136048823894 0.0255790215540446 -418.39507207484746 -0.0092403967386546 0.0382105205509175 -413.5160170241859 -0.0185457390516984 0.0764843005359449 -412.40901925092254 -0.0152433179000173 0.0625934293811475 -410.6286426072384 -0.0273568100999926 0.1140243481847434 -416.804253741462 -0.0427605127242254 0.1754016572925562 -410.1954025288953 -0.0415600870581402 0.1693796047810127 -407.5535369886501 +r_3653 carbon dioxide transport, cytoplasm-vacuolar membrane -0.0005557827127659 0.0006390402613971 -114.9802335910848 -0.000772484090087 0.0009017167484978 -116.72949126969256 -0.0025748010260564 0.001466258992686 -56.94649714085676 -0.0034672987901735 0.0022264626902855 -64.21317645295976 -0.0049756450740733 0.0037024324900921 -74.41110519286153 -0.0047374538083107 0.0034292493799385 -72.38591696498975 -0.0068210530487442 0.0050466603367778 -73.98652819020317 -0.008319581857463 0.0070923107006302 -85.24840337099484 -0.0094494079893756 0.0073187453222157 -77.45189254654387 +r_3654 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) transport, vacuolar membrane-cytoplasm 5.750242546930308e-05 0.0014402273357499 2504.637541800457 0.0001921346421776 0.0035361774732611 1840.468451281092 5.671269912711823e-05 0.0017927014468475 3161.0229709386986 1.6772923060371226e-05 0.0011860117538536 7070.990247703689 0.0001155082263917 0.0042078870393812 3642.932777020846 0.0001097692701286 0.0038682447718546 3523.977855842977 0.0004026776819628 0.0100598926474252 2498.24936867356 0.0005118716245688 0.0137393695149419 2684.143612475971 0.0001823829719332 0.0077442770636314 4246.162337163949 +r_3655 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) transport, vacuolar membrane-cytoplasm 2.230183596494132e-05 0.00090396088771 4053.302558278719 5.4204460127590304e-05 0.0018979680993061 3501.4980221896044 4.644591275380314e-05 0.0016054330467441 3456.564747158852 0.000101730065821 0.0029038384506279 2854.4545087926003 0.0001689755311662 0.005292802065034 3132.289053037577 0.0001390234096497 0.0043244711372698 3110.606442587125 0.0005546075495087 0.0114969220013201 2072.983321540424 0.0003456886559564 0.0111156306278022 3215.5034411083548 0.0003685773734061 0.011599281598338 3147.041146651469 +r_3656 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-16:1) transport, vacuolar membrane-cytoplasm 5.311945679915998e-05 0.0013502895073286 2541.986663067697 5.354082764931032e-05 0.0018924174332136 3534.531527246538 4.526908964208765e-05 0.0016000528390511 3534.537256440835 0.0001755618889558 0.0037837150129537 2155.2029517666474 0.0002381190790113 0.0060908048863252 2557.881926813532 5.472073428677427e-05 0.0027357662750102 4999.505782712996 0.0001509492731727 0.0061612484981822 4081.6682112339295 0.0001527911142967 0.0076387949642438 4999.502097620139 0.0002201662975559 0.008986456511 4081.667635218695 +r_3657 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-16:1) transport, vacuolar membrane-cytoplasm 8.846982111099801e-05 0.001766532790886 1996.7631546013065 6.719111002540985e-05 0.0021239114472294 3161.000683611587 4.479311278820728e-05 0.0015834384201064 3535.004203868032 0.0001507317356098 0.0035499693798652 2355.157237128577 0.0001672459280148 0.0052866812199842 3161.0223834663843 5.333310834563557e-05 0.0026672924764587 5001.19449099577 0.0001252155334184 0.0053182792401361 4247.299911555326 0.0004172670248125 0.0122895641685235 2945.251706397186 0.0007102717219923 0.0159467588043586 2245.1631270954013 +r_3658 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-18:1) transport, vacuolar membrane-cytoplasm 5.140802101648313e-05 0.0013731850725271 2671.149453675463 8.050260956768296e-05 0.0022253355899297 2764.3024268161016 3.944503438119047e-05 0.0014383636303131 3646.50114489203 6.68785845972565e-05 0.00236383966529 3534.524062560762 0.0002337918691232 0.0060245308329323 2576.8778253605587 0.0001368021791713 0.004324328819846 3161.008725181541 0.0002013387602217 0.0071162663998015 3534.474133029702 0.0005330626911305 0.0142385866218231 2671.090447471742 0.0004397411751216 0.0126879341765542 2885.318658878149 +r_3659 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-18:1) transport, vacuolar membrane-cytoplasm 7.382137799207652e-06 0.00052199889401 7071.107424546424 2.685392958987573e-05 0.0013425607781858 4999.494668713386 5.094618726710064e-05 0.001652014047984 3242.6647343065733 4.171310504793124e-05 0.0017736114494286 4251.928614258407 0.0001838697284311 0.0054182090766518 2946.765148827007 0.0002512137737827 0.0055986949242678 2228.657624923745 0.0003013981440071 0.0086963530343974 2885.337288006818 0.0006111649795138 0.0152684233305799 2498.249055880848 0.0003668764383715 0.0115970125752217 3161.013181085494 +r_3660 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transport, vacuolar membrane-cytoplasm 2.214646145125247e-05 0.0009039473750761 4081.6785880933735 7.378323160114668e-05 0.0021732753899198 2945.486857593943 7.947848324744549e-05 0.002122876786195 2671.0081766228304 5.848588922108743e-05 0.0021332883350756 3647.526546123596 0.0001674344552356 0.0052926267814935 3161.014125823217 0.0002285709046223 0.0054629989708857 2390.0675284603017 0.0001002604923875 0.0050125675402463 4999.544108431062 0.0004194020024292 0.0123552003431255 2945.908763325593 0.0003669440934522 0.0115991470074394 3161.012049087515 +r_3661 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm 1.1772406504549169e-05 0.0006072819211397 5158.51980565785 0.0001006601588002 0.0025543385191689 2537.5864191087016 9.52618226367368e-05 0.0022181333927018 2328.459955212401 4.171307161119322e-05 0.0017736106749124 4251.930165786427 0.0001674344070875 0.0052926252066647 3161.014094252549 0.0001771118668825 0.0048185220124812 2720.609351193957 0.0003766855078913 0.0095607653463711 2538.129327005688 0.0003051021665898 0.010783797182753 3534.4872516916366 0.0004402071267302 0.0127013327312316 2885.308292388286 +r_3662 H2O transport, cytoplasm-Golgi membrane 0.0027582190546679 0.0139510744244342 505.8000886776444 0.0049546740088433 0.0251680364526553 507.9655373438157 0.0039701227212334 0.0207206572624107 521.9147799031587 0.0063978960244334 0.0319033189336976 498.6532887039625 0.0134289057277734 0.0655564927963626 488.1744955642957 0.0090676259366791 0.0488247565642087 538.4513753121358 0.0167900328563231 0.0901278758508921 536.7939218591209 0.028372892226656 0.143888906034996 507.1351376008612 0.0289680531392733 0.1426245636138045 492.3512219757756 +r_3663 phosphate transport, cytoplasm-Golgi membrane -0.0027582190546679 0.0139510744244342 -505.8000886776416 -0.0049546740088433 0.0251680364526553 -507.9655373438157 -0.0039701227212334 0.0207206572624107 -521.9147799031587 -0.0063978960244334 0.0319033189336976 -498.6532887039625 -0.0134289057277734 0.0655564927963626 -488.1744955642957 -0.0090676259366791 0.0488247565642087 -538.4513753121358 -0.0167900328563231 0.0901278758508921 -536.7939218591209 -0.028372892226656 0.143888906034996 -507.1351376008612 -0.0289680531392733 0.1426245636138045 -492.3512219757756 +r_3664 H+ transport, cytoplasm-Golgi membrane -0.0044239602590294 0.0233952156807406 -528.8296980740279 -0.0079098125624021 0.0420402005796045 -531.4942705397967 -0.0064245376832855 0.0349893937929463 -544.6211932724209 -0.0101260828956421 0.0528598902908951 -522.0171594056775 -0.0207055235509076 0.1063391551740987 -513.5786830632327 -0.0140345642765276 0.0793867455249158 -565.651658011839 -0.0274428340895394 0.1536238400824843 -559.7958271410528 -0.0439168172225538 0.2338934359761115 -532.5828481395358 -0.0447340684476706 0.2316454624619325 -517.8278446390555 +r_3665 carbon dioxide transport, cytoplasm-Golgi membrane -0.0003530668218392 0.0005661125880337 -160.34148580844757 -0.0006578868955357 0.0007675421749347 -116.66780112859637 -0.0009024286290309 0.0013403829275662 -148.53062995194114 -0.001549967376878 0.0019851408912218 -128.07630152966905 -0.0022269329242036 0.0031904446432377 -143.26631074344547 -0.0038539631274206 0.0034889670659056 -90.5293317697292 -0.0027813703056643 0.004500940240077 -161.8245593156265 -0.0033799826599297 0.0060204105502954 -178.11956912289898 -0.0036467825666703 0.0063465526277237 -174.0315610184117 +r_3666 ATP transport, cytoplasm-Golgi membrane 0.0010924778503064 0.0089142983837086 815.9706287141814 0.0019995354552845 0.0162266664666144 811.5218174166093 0.0015157077591812 0.0130085158320458 858.2469643800166 0.0026697091532249 0.0209460277434945 784.5808865805654 0.0061522879046389 0.0449415554416473 730.4852461108032 0.0041006875968302 0.0332338213492606 810.4450915731771 0.0061372316231066 0.0552296721754429 899.911809870488 0.0128289672307578 0.0981527265417454 765.0867351693066 0.0132020378308755 0.0975229825179895 738.6964328333668 +r_3667 ADP transport, cytoplasm-Golgi membrane -0.0010924778503064 0.0089142983837086 -815.9706287141814 -0.0019995354552845 0.0162266664666144 -811.5218174166093 -0.0015157077591812 0.0130085158320458 -858.2469643800166 -0.0026697091532248 0.0209460277434944 -784.5808865805653 -0.0061522879046389 0.0449415554416473 -730.4852461108032 -0.0041006875968302 0.0332338213492606 -810.4450915731771 -0.0061372316231066 0.0552296721754429 -899.911809870488 -0.0128289672307578 0.0981527265417454 -765.0867351693066 -0.0132020378308755 0.0975229825179895 -738.6964328333668 +r_3668 H2O transport, cytoplasm-mitochondrial membrane 0.0006125708883261 0.0049036915537042 800.5100547796902 0.0012316743971228 0.0093953855574414 762.8140667199542 0.0009168779192906 0.0074767589695392 815.458504587364 0.0013344952488191 0.0109589134294613 821.2028809513002 0.0026780891402996 0.0218943132515365 817.5348953876425 0.0019574736865061 0.016992234994273 868.0696507651069 0.0044328269920928 0.0344906349349433 778.0731121802494 0.0052642286294438 0.046362800737736 880.7140419095737 0.0045454453228232 0.0423552131446355 931.816579818142 +r_3669 carbon dioxide transport, cytoplasm-mitochondrial membrane -0.000232950770748 0.0005306001265923 -227.77350119450057 -0.0003788627785548 0.0007550321214978 -199.28907357377625 -0.0005655942099541 0.0012607262145899 -222.90295628948425 -0.0009761348892513 0.0018072681098408 -185.1453246617252 -0.0014388705904626 0.0031141964191736 -216.4333915652798 -0.001394749019235 0.0030234968938274 -216.7771299445513 -0.0020357859322194 0.0046918952312547 -230.47095261826144 -0.00224695090429 0.0061660293486445 -274.41762687702936 -0.002525381149424 0.0064848864377537 -256.78842337255264 +r_3670 palmitoleoyl-CoA transport, cytoplasm-mitochondrial membrane 8.75361313327922e-10 3.626569342547176e-09 414.293993500786 6.213076492973719e-10 4.000734519434033e-09 643.9216584502714 7.633585931801637e-10 3.211386087771705e-09 420.6916796983999 9.007112987537864e-10 3.148732586651888e-09 349.58288976816846 6.306729144810982e-10 3.0948838955958604e-09 490.727257272853 9.61517826294671e-10 3.077378076488855e-09 320.05418852689564 6.92436025619929e-10 2.9961773035293363e-09 432.7009561420346 8.288709002404853e-10 2.939627458959601e-09 354.6544411327154 1.0701799830798042e-09 2.954867297872992e-09 276.10937829068376 +r_3671 oleoyl-CoA transport, cytoplasm-mitochondrial membrane 6.890269893841576e-10 3.927036828443207e-09 569.9394782711101 2.2778070466923707e-10 4.3317772805150126e-09 1901.7314424438343 3.640250669799442e-10 3.860587328593102e-09 1060.527880846678 7.111580618993411e-10 3.414037296797952e-09 480.0672986367947 6.040407892280315e-10 2.9343504152992837e-09 485.786799108286 7.75781242947675e-10 3.0465844986335756e-09 392.7118019839856 4.34587024620759e-10 3.512625552764538e-09 808.2674709006371 9.145943514906507e-10 2.954035706397301e-09 322.988623490039 9.250681169862947e-10 3.596513621779438e-09 388.783653413138 +r_3672 diglyceride (1-16:0, 2-16:1) transport, mitochondrial membrane-cytoplasm 5.23647280145406e-05 0.0010249705167334 1957.3681666958737 8.050700869081267e-05 0.0017133984568193 2128.259992120244 9.339847209852287e-05 0.0017015816043741 1821.8516493280435 0.0001187693149457 0.0023266365953631 1958.954294235471 6.252582546322086e-05 0.0023078766741384 3691.07749804282 0.0001652162613726 0.0035112956029381 2125.272399801791 0.0005185803001676 0.00839943469547 1619.6979894443143 0.0003373426804999 0.0081260895486032 2408.853079770356 0.0005200853197783 0.0101876810683671 1958.8480353009024 +r_3673 diglyceride (1-16:1, 2-16:1) transport, mitochondrial membrane-cytoplasm 5.25487499708277e-05 0.00102184990523 1944.5750960723155 0.0001179097453193 0.0020637887234868 1750.3122561222729 6.354149773458107e-05 0.001387068738745 2182.9336546943955 9.536221717437963e-05 0.0020579160258769 2157.999349064912 0.0002225682198012 0.0044819040484927 2013.721479416727 0.0001839336515726 0.0036766540251804 1998.902318169592 0.000309989367794 0.0064592361610201 2083.6960335076656 0.0004614120523964 0.009722396779973 2107.0964075338325 0.0002449088121233 0.0069562842330504 2840.3568547578548 +r_3674 diglyceride (1-18:0, 2-16:1) transport, mitochondrial membrane-cytoplasm 4.670132226070491e-05 0.0009564669077663 2048.051021825485 9.522032212692535e-05 0.0018651634887598 1958.7872074972088 5.4741768901168873e-05 0.00128851037628 2353.7974788617826 0.0001190409531269 0.0023297342217451 1957.0863308363007 0.0001616918488559 0.0038026362188158 2351.779787121056 0.0001489903348865 0.0033283906653904 2233.9641480265363 0.0002155810816773 0.0053850641863329 2497.9298482195063 0.0002495777220393 0.007201132867126 2885.3267864949275 0.0003609335423927 0.0085000819751656 2355.026889110021 +r_3675 diglyceride (1-18:1, 2-16:1) transport, mitochondrial membrane-cytoplasm 5.237835487088647e-05 0.0010252506173743 1957.393698029736 0.0001221955870431 0.0020980356979703 1716.948826661906 9.20232618913977e-05 0.0016784099874721 1823.8975156661493 0.0001555939160788 0.0026642117053642 1712.2852695691 0.0003639090882641 0.0057443052184504 1578.5000715018152 0.0001635807771516 0.0034804323974032 2127.653663227436 0.0002952238213479 0.0062996612101879 2133.85938215464 0.0004993969757722 0.0101828163565832 2039.0224311706515 0.0002247537218606 0.0065404469905259 2910.050581756645 +r_3676 diglyceride (1-16:0, 2-18:1) transport, mitochondrial membrane-cytoplasm 6.640901691635446e-05 0.0011415225303071 1718.9270121932211 9.76441842143122e-05 0.0018713130914554 1916.4613914416504 6.19656817607976e-05 0.0013842670177353 2233.925260564289 0.0001093441277589 0.0022295533251603 2039.0242904275483 0.0002375208429144 0.00465254181546 1958.793071955724 7.8480559478869e-05 0.0023693207503961 3018.9906470201418 0.0003581888762214 0.0069429670355305 1938.3536163300928 0.0004589733240466 0.0097754875871506 2129.85963998136 0.0005210817467002 0.0101967051436503 1956.8340684012176 +r_3677 diglyceride (1-16:1, 2-18:1) transport, mitochondrial membrane-cytoplasm 3.588794500481454e-05 0.000844575643137 2353.3686395913605 0.0001023603853669 0.0019319143405588 1887.365247438298 9.276826185992918e-05 0.0016888250176459 1820.477158660076 6.913787730295187e-05 0.00173575469225 2510.5698351776928 0.0002908294260155 0.0051338559854531 1765.2464043231755 0.0002385398888039 0.004210506827317 1765.1164542875665 0.0005188520638792 0.0084035868378119 1619.6498815060495 0.0006254140768491 0.0114023760878194 1823.172280557773 0.0004009615653765 0.0089576193516961 2234.034412571212 +r_3678 palmitate transport, mitochondrial membrane-cytoplasm -2.2089888390492875e-09 8.119693260806053e-09 -367.57511478874807 1.6775764026625283e-09 7.334063006292502e-09 437.1820558904146 1.850431280589737e-09 8.737152627240665e-09 472.1684462908621 9.54466985080391e-10 8.339258407802235e-09 873.7084192702431 1.421072039770796e-09 8.00301768692948e-09 563.1676271823828 -4.351143000123657e-10 6.9450200493797875e-09 -1596.1369344060654 7.707606773785727e-10 8.779840147887501e-09 1139.1136581783771 4.1731161593915065e-11 7.3659771529630045e-09 17651.02353162644 2.5375282720621125e-10 8.02174340719949e-09 3161.2429684106146 +r_3679 stearate transport, mitochondrial membrane-cytoplasm -1.448733412148196e-09 7.307346169356979e-09 -504.3955021732793 3.2416686694158923e-09 7.80947444693541e-09 240.9090886004268 3.8838116040853364e-09 7.421217722133222e-09 191.0807855439468 1.8216930549339678e-09 6.633429219708193e-09 364.1353960120706 3.0541717409107642e-09 6.908232525594248e-09 226.19004796155275 -1.0453416495837842e-09 6.514242267226582e-09 -623.1687285989522 2.392160999928233e-09 7.53954055836555e-09 315.17697005309185 1.6882029638789801e-09 7.546807507910492e-09 447.0320020390326 1.020737677418459e-09 7.278632605603298e-09 713.0757261759594 +r_3680 coenzyme A transport, mitochondrial membrane-cytoplasm 1.7219654731279375e-09 5.517061821069806e-09 320.393289364165 8.446944947791355e-10 4.503840211905832e-09 533.1916142159139 1.1273836601601127e-09 4.7232143300981395e-09 418.9535911339482 1.6118693606531286e-09 4.784632973565502e-09 296.8375161388247 1.2347137037091359e-09 4.537886417042535e-09 367.5253950296752 1.7372990692423615e-09 4.5984115712538315e-09 264.68739048246914 1.2042099660765603e-09 4.845067987315991e-09 402.34411969714216 1.743465251731146e-09 4.538405651370629e-09 260.30949838915865 1.9952481000661103e-09 4.757584971027165e-09 238.4457838035044 +r_3681 laurate transport, ER membrane-lipid particle 0.0002246721116918 0.0020731137394486 922.7285593379412 8.770231918291661e-05 0.0016998929893126 1938.25317865003 0.0002882760973635 0.0028234539431651 979.4270038296868 0.001540367033419 0.0174681822256182 1134.0272705554676 -6.401020071135787 79.74994502331748 -1245.8943127351697 0.0003549013044023 0.0059550085163789 1677.9336797329877 -0.0006844175393122 0.01057315596202 -1544.8400069706895 -4.597129897316928 67.67177382425731 -1472.043978216785 0.0066862496221892 0.0589672588635843 881.918297933324 +r_3682 myristate transport, ER membrane-lipid particle 1.7527349244044602e-10 1.0319732868617914e-08 5887.78869236278 2.142046158856783e-09 1.0765450051786948e-08 502.577874303722 0.0001843290397231 0.0023677675513191 1284.5331125659848 0.0009157358733007 0.0147691687586354 1612.8197211932654 4.20047038834985 64.6765621126343 1539.7456982917197 1.576843102570931e-09 1.3482714199964692e-08 855.0447522636892 -0.0017319909599994 0.0170867395850712 -986.5374577403404 -0.0002764177465607 0.0073595587480946 -2662.476935603447 -0.0053319139701326 0.0385241463787666 -722.5200292908806 +r_3683 lignoceric acid transport, ER membrane-lipid particle 3.824235429671644e-10 1.6295300852723408e-08 4261.061106826928 -1.924311834403166e-09 1.1588515835548752e-08 -602.2161080323544 2.704809603649926e-10 5.170177159719969e-09 1911.4754520034328 5.460923500843597e-10 8.146091547028306e-10 149.17058526401095 -1.6468859394220927e-09 1.0533935948234804e-08 -639.6275355858135 -1.206471150061228e-09 8.537386559283032e-09 -707.6328811384973 7.118363701859619e-11 3.222824789956233e-09 4527.479804262172 -5.697980743330703e-10 5.503314725739393e-09 -965.8359642897776 -3.817490418040825e-09 1.1869316559818612e-08 -310.9193543414331 +r_3684 cerotic acid transport, ER membrane-lipid particle 7.335835570943822e-10 1.953100844772804e-08 2662.410881329936 0.0001529452738462 0.0033253428452733 2174.204381507491 0.000648769102667 0.0071253184510694 1098.2826435132629 0.0012846069216512 0.0181120356358282 1409.9282302283295 2.200311203192873 46.85695995469365 2129.560577008356 7.662402062917135e-10 1.1113741383181204e-08 1450.425244189042 6.938404779695633e-10 3.6786758986681804e-09 530.1904422517061 4.602822284907732 67.67360156637262 1470.2631858776883 3.522790189224389e-09 1.2567530262462916e-08 356.74932617062564 +r_3685 TAG (1-16:0, 2-16:1, 3-16:0) transport, ER membrane-lipid particle 3.636303693432088e-05 0.0011838921502694 3255.757082137581 9.619515013315318e-05 0.0027594795891388 2868.6265215233457 6.846547017620094e-05 0.0021540037649993 3146.116954219185 7.413829267911798e-05 0.0025951111811478 3500.3654486352084 0.0002978458160616 0.0075171454266624 2523.83784538575 0.0004210577241729 0.0080192358534354 1904.545479883457 0.0002990206029197 0.0093746755865582 3135.1269762085903 0.0009910006047517 0.0211930393676059 2138.5495897769624 0.0003982642651646 0.0128562066572628 3228.0593017676174 +r_3686 TAG (1-16:0, 2-16:1, 3-16:1) transport, ER membrane-lipid particle 7.463759406100132e-06 0.0013916210658552 18645.04186345993 -3.3920329639201346e-05 0.0039101965924925 -11527.590191734333 -0.0001134443370357 0.0032697377013377 -2882.239684036693 -5.148197608100734e-05 0.0040173994208175 -7803.506637927217 2.176824135780268e-05 0.0072003232332554 33077.19312233049 -7.407129872481591e-05 0.0071857169192786 -9701.08131352538 9.83638503875036e-06 0.0116567662532326 118506.60793890191 0.0001444555677131 0.0122106142639702 8452.851251959682 -0.0001666866534583 0.0120017779102948 -7200.203292395428 +r_3687 TAG (1-16:0, 2-16:1, 3-18:0) transport, ER membrane-lipid particle 7.016470566829252e-05 0.0017551891879157 2501.527186921436 3.147763520633864e-05 0.0010055293438291 3194.4246676658163 5.414186248042687e-05 0.0019234650093482 3552.6391616905626 0.0001649028003421 0.0039592192768864 2400.941202133416 0.00012241074368 0.0044087854888653 3601.632794902456 6.423921014773487e-05 0.0023035912474857 3585.958236703219 0.0003229866744802 0.0095297417362534 2950.506163014117 0.000242086317624 0.0079707768133505 3292.535031132636 0.0008903011664627 0.0194996978049472 2190.236129019315 +r_3688 TAG (1-16:0, 2-16:1, 3-18:1) transport, ER membrane-lipid particle -2.40664530083622e-05 0.0018393949309399 -7642.983078149634 -1.5032290325761685e-05 0.0024844684660826 -16527.544454253013 2.800612171629385e-05 0.0021523257860975 7685.197571805581 3.573875435663703e-06 0.0034734134121714 97188.9892275 8.055153055749922e-05 0.0056861676839925 7059.043626655446 0.0001230004350555 0.0062645540660133 5093.115372466837 -0.0001963835735649 0.0126120753800353 -6422.164110310056 0.0004733651114379 0.0179794120073928 3798.212325529621 -4.4668507646464165e-05 0.0069294373943896 -15513.0264239713 +r_3689 TAG (1-16:1, 2-16:1, 3-16:0) transport, ER membrane-lipid particle 4.111074151650513e-05 0.0013151481962275 3199.03788575432 9.389005180152524e-05 0.0027182789522651 2895.1724917687056 6.904950045847766e-05 0.0021544305409823 3120.124731789874 7.877573327694764e-05 0.0027981540141095 3552.05073657931 0.0002189236640905 0.006403238504894 2924.872709166831 0.0001899173907029 0.0056156255868015 2956.8780226061244 0.0002936648768873 0.0094720919515261 3225.476622170057 0.0004538893820104 0.0144899321840588 3192.3928512883936 0.0004827148519867 0.0142563287941219 2953.364441853569 +r_3690 TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle -2.532341226042632e-05 0.0022504256217608 -8886.739269642812 1.2671505001070584e-05 0.0025379489543665 20028.788641539635 -6.74799141380878e-05 0.0026905633572338 -3987.206254779766 -0.000140190975058 0.0045475619803438 -3243.833619432582 -5.1815428775663166e-05 0.0073359396065974 -14157.82862351417 -1.4093606736798765e-05 0.0065662634812494 -46590.36968943348 -0.0004117390921189 0.0122264620447058 -2969.468354774021 -0.0002665765604313 0.010552893581076 -3958.672722012488 -0.0011151509428504 0.0231047251700151 -2071.892179094329 +r_3691 TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle 2.6086363783068967e-05 0.0010843677606316 4156.837532624603 2.72586309806228e-05 0.0009101486529917 3338.9375043768773 8.369992807824022e-05 0.0022635753452042 2704.3934172659265 0.0001136554487513 0.0033089619542874 2911.3975534297424 0.0002149338393301 0.0063921716644527 2974.018276681479 7.189164977829075e-05 0.0023903073146324 3324.874755279651 0.0003539666810499 0.0102412009759299 2893.2669440955933 0.0003734925699709 0.0096397850055576 2580.9844105621064 0.0006606933722682 0.0165229435200642 2500.848988894605 +r_3692 TAG (1-16:1, 2-16:1, 3-18:1) transport, ER membrane-lipid particle -8.35127474817066e-06 0.0020657874879756 -24736.193578448903 -1.5209565125812316e-05 0.0025532168975965 -16786.915841949347 -2.76658511543734e-05 0.0027122134425979 -9803.470088319353 -5.4066080889526726e-05 0.0045289021744471 -8376.605257741998 -0.0002180160340938 0.0084406819369484 -3871.5876894234166 -3.199825017815726e-05 0.0040539915961501 -12669.416526149576 -0.0001196375228684 0.0105261147776839 -8798.338953619217 -0.0003526644523361 0.018847410902317 -5344.2899553577945 -0.0001480612193423 0.01904878267914 -12865.477377366477 +r_3693 TAG (1-18:0, 2-16:1, 3-16:0) transport, ER membrane-lipid particle 2.180609803088055e-05 0.0009285527630705 4258.225207258862 7.998189017704063e-05 0.002529047833105 3162.025587926238 6.257747529260358e-05 0.001942416023694 3104.017882811012 0.0001621041293316 0.0040138132832659 2476.0709673557462 0.0002232776525934 0.0064041167849315 2868.2300761165548 0.0003029435763134 0.0068371311409845 2256.8991969350145 0.0002396524280303 0.0083333285243763 3477.2560381995886 0.000270483615293 0.0110810842395558 4096.767276476904 0.0001839188070604 0.00880356433575 4786.658023969622 +r_3694 TAG (1-18:0, 2-16:1, 3-16:1) transport, ER membrane-lipid particle 2.7714921816154875e-05 0.0015977362351147 5764.895335852784 -2.024451971572309e-06 0.0032113272805883 -158626.99267171393 -0.0001038220965455 0.0034160676642298 -3290.308882109774 -3.348012222330176e-05 0.003859902761914 -11528.9386823912 0.0001493273980732 0.0086179243035959 5771.1608283496125 -9.045520424236128e-05 0.0067348994467582 -7445.563252185137 -0.0005222132065231 0.0148448166734069 -2842.6735455891053 -0.0001787605157403 0.0199714720045765 -11172.194218537998 -0.0002549664404794 0.0184920191596851 -7252.726721569835 +r_3695 TAG (1-18:0, 2-16:1, 3-18:0) transport, ER membrane-lipid particle 5.227044024396956e-05 0.0015114422043532 2891.581163844633 2.6870794218419298e-05 0.0009091018329706 3383.2339512596823 9.114294952015895e-05 0.0024322829729128 2668.646325051081 5.614606775986386e-05 0.0023013561457792 4098.873238322108 0.0002514463702673 0.0069731198011107 2773.2036034948155 5.007267580066482e-05 0.0020180261773802 4030.194402659448 0.0003827077510979 0.0103775560448326 2711.6137614304143 0.0003151641716985 0.0091033441012486 2888.445108524749 0.0009039372278719 0.0193007258462994 2135.184308288325 +r_3696 TAG (1-18:0, 2-16:1, 3-18:1) transport, ER membrane-lipid particle -1.2245176189614116e-05 0.0015121913405217 -12349.282012000003 -7.994304054740176e-05 0.0034243888657569 -4283.535930468448 8.508829613991656e-06 0.0018754398969539 22041.102972259345 1.3849702589771703e-05 0.0029721338954724 21459.91133172405 -0.0001122362735976 0.0079992435915165 -7127.146451953088 -6.187607999213007e-05 0.0054025286349949 -8731.207011953637 0.0001856002648431 0.0109418873267783 5895.40501789034 3.273087453895773e-05 0.0143361915457704 43800.20927551718 0.0001100816551075 0.0159725012443823 14509.684859635325 +r_3697 TAG (1-18:1, 2-16:1, 3-16:0) transport, ER membrane-lipid particle 4.6836087873169296e-05 0.0013303712065449 2840.4831978014927 0.0001425875470708 0.0033482260576777 2348.189674665708 6.479029091207577e-05 0.0020481232466247 3161.1576638916267 0.0001324093357748 0.0035410100297457 2674.290305154984 0.0002893417317488 0.0073505351658475 2540.4338051819605 0.0001940291832942 0.0052916764967902 2727.258037655566 0.0002654898746854 0.0083671597196249 3151.592779023127 0.0009757070531514 0.0208235070944912 2134.196634864321 0.0003845045199813 0.012579421758669 3271.5926874613474 +r_3698 TAG (1-18:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle -1.8290339114724944e-05 0.0014932627339547 -8164.215680138 -6.185386641961133e-05 0.0031499432079897 -5092.556682909433 -4.988638413479006e-05 0.0034013997524272 -6818.292829636394 -2.820170635371532e-05 0.0036723364003759 -13021.68157598788 2.590447781765885e-05 0.0057094277510328 22040.312069679352 -5.799977372282184e-06 0.0046603502949718 -80351.18063121167 -0.0003090048479631 0.0125024845714171 -4046.0480325243566 0.0002670180337965 0.0241816791582948 9056.196997061375 -0.0010317298175608 0.0259927021831705 -2519.3322651682 +r_3699 TAG (1-18:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle 4.372322784855293e-05 0.0013843823348841 3166.240012469626 2.742041033059342e-05 0.0009079985216807 3311.396549991295 6.450816917604085e-05 0.002054002447355 3184.09664014762 7.106156116420617e-05 0.0025687717333527 3614.854066345232 0.000172612822215 0.0057389691408975 3324.7640976223765 6.509377775617843e-05 0.0023084653189973 3546.368637021155 0.0005017140790077 0.0119641476241691 2384.6545522165466 0.0001049835799803 0.0046602606630023 4439.037670343524 0.0006753129768221 0.0166239013440733 2461.6588033451285 +r_3700 TAG (1-18:1, 2-16:1, 3-18:1) transport, ER membrane-lipid particle 9.982840327113795e-06 0.0016492261529507 16520.61035646675 6.213224924705768e-05 0.0035296634261071 5680.887894581185 -5.929547211129284e-06 0.0022222127636928 -37476.93853456316 5.3929962384712895e-05 0.0031354372344708 5813.905843479063 6.022053320720984e-06 0.0067578619152088 112218.5665802073 -2.542294107319934e-05 0.0066517810936477 -26164.482993905007 0.0001107242704273 0.0102830051828358 9287.03810207524 0.0002745808641799 0.0174063375510404 6339.239117418039 0.0004917714819038 0.0147058024409305 2990.373167634517 +r_3701 TAG (1-16:0, 2-18:1, 3-16:0) transport, ER membrane-lipid particle 3.23912403838359e-05 0.0011548747019431 3565.3920265413035 8.032977012782716e-05 0.0025132161151681 3128.623561562451 7.662858922308566e-05 0.0021969245309527 2866.9776557635887 0.0001452501875208 0.0036182274661455 2491.0311841257057 0.0001907341811585 0.0060998748923506 3198.102644894616 0.0001923768726569 0.0055269364431638 2872.973433255852 0.0002397998518947 0.008428085909367 3514.633492378683 0.0004252608464286 0.0135497398877464 3186.21852953028 0.0005260661767812 0.015229631003964 2895.002886736724 +r_3702 TAG (1-16:0, 2-18:1, 3-16:1) transport, ER membrane-lipid particle -4.214842976022126e-07 0.0012427863862567 -294859.4747958232 -3.3389650696972814e-05 0.0027836235089025 -8336.785353537514 -4.758024396904159e-05 0.00280135011446 -5887.63293496929 3.328529129324901e-05 0.0016994977574666 5105.852138993787 -7.83893410950728e-05 0.0055089593246334 -7027.689284888871 1.923567047765421e-05 0.0041066608439504 21349.19522935842 -1.6096308869685138e-05 0.0102249684696392 -63523.6845442024 0.000173861098586 0.0147232757155065 8468.412908492977 -0.0004503433462111 0.0218663583020714 -4855.486038827817 +r_3703 TAG (1-16:0, 2-18:1, 3-18:0) transport, ER membrane-lipid particle 6.168922674792827e-05 0.0016477728571447 2671.086904489456 1.652596149949791e-05 0.0006912667025377 4182.913669251836 0.0001075768711816 0.0026883275239672 2498.982815207072 0.0001392181371124 0.003707560898239 2663.1306632432675 0.0001601368850232 0.0056780009707171 3545.717134371258 9.85451879874049e-05 0.0028442071341683 2886.1958582208163 0.0003584097698812 0.010354706448417 2889.0692493811257 0.0003806582182608 0.0098587212652553 2589.9142044790447 0.000214074215511 0.0091176617073794 4259.112516475517 +r_3704 TAG (1-16:0, 2-18:1, 3-18:1) transport, ER membrane-lipid particle 2.135671346355405e-05 0.0012615655601508 5907.114698634571 1.731358566811879e-05 0.0025457932112465 14704.020646251198 -2.6945508257973334e-05 0.0026954227364526 -10003.235829315234 0.0001028503478187 0.0030730139243956 2987.849812437916 -6.0661724424203446e-05 0.0069458406899384 -11450.120740661116 7.162182927648343e-05 0.003914496540585 5465.507625438914 -0.0001166796838867 0.0119151183814352 -10211.819216960832 0.0002223486657888 0.0170164179952116 7653.033551984262 0.000178251996409 0.0119423813587471 6699.7181514558 +r_3705 TAG (1-16:1, 2-18:1, 3-16:0) transport, ER membrane-lipid particle 4.105116625534051e-05 0.0013112472459601 3194.177816542809 8.049094609536905e-05 0.0025358039683009 3150.421371984404 9.525624068880793e-05 0.0025175077165691 2642.8795618688528 0.0001280108832483 0.0034547573089113 2698.7996811253247 0.0002230224804708 0.0065158397911527 2921.606726549422 0.0001575816392396 0.0048305790472423 3065.445359339993 0.0004817012032168 0.0119549712727525 2481.8230041602105 0.0002712747138188 0.0112066271634391 4131.099064000463 0.0008395220124768 0.0188476624422339 2245.046843575615 +r_3706 TAG (1-16:1, 2-18:1, 3-16:1) transport, ER membrane-lipid particle -2.977067934206084e-06 0.0012258752405042 -41177.2679561365 -1.607033435562523e-05 0.0033544450804296 -20873.523886921867 -6.72932517540482e-05 0.0024046593923731 -3573.4034686895184 -3.3425851154326524e-06 0.0035062339297372 -104895.87575643328 0.0001789310532463 0.0070509588580762 3940.600991360457 -5.969569230729273e-06 0.0047643860938426 -79811.2210394884 -0.0002083502125329 0.0114500166368092 -5495.562734307321 -7.8671454166794e-05 0.0139714814209893 -17759.276943537814 -8.733279434285143e-05 0.0160208930166129 -18344.647205170226 +r_3707 TAG (1-16:1, 2-18:1, 3-18:0) transport, ER membrane-lipid particle 2.5908697071635508e-05 0.0010645287559339 4108.76993540285 1.641557827639269e-05 0.0006649891669576 4050.964003588893 7.693676801029777e-05 0.0021726468358942 2823.9382704553227 1.980469757805685e-05 0.001423556366055 7187.973259598202 0.0002960665475626 0.0073525515073551 2483.411776130529 6.467333183407882e-05 0.002322446900776 3591.042605836842 0.0004440519424161 0.0112809280977249 2540.452370581571 0.0002821117866015 0.0081951440467132 2904.927917204448 0.0004352857046434 0.0137448992847396 3157.6730267300845 +r_3708 TAG (1-16:1, 2-18:1, 3-18:1) transport, ER membrane-lipid particle -2.5287813873469826e-05 0.0016124917041365 -6376.556361118685 1.5543923443568337e-05 0.0011479395696561 7385.133964560183 1.9376329228570064e-05 0.0021421081512317 11055.283619320917 8.615004996264007e-05 0.0034610668997351 4017.4868165904713 -0.0001098226771376 0.0085600145423102 -7794.396171548256 6.723130780633102e-05 0.004703838017135 6996.499355159159 -7.996640794904159e-05 0.0094039199967047 -11759.83795933088 3.7495257415113e-05 0.0140628977868243 37505.80408378824 8.782752892525609e-05 0.02057067341113 23421.6693363152 +r_3709 TAG (1-18:0, 2-18:1, 3-16:0) transport, ER membrane-lipid particle 6.258777211558589e-05 0.0015864634640646 2534.7818119085905 0.0002081871746285 0.0040745897273989 1957.176149140576 7.441891936606404e-05 0.0021692057342577 2914.8578785288373 9.65114088667403e-05 0.0029822871435129 3090.087667905476 0.0001309553473074 0.0047192840545193 3603.735281949647 0.000311692647802 0.006814574619319 2186.312275047959 0.0003086819575653 0.0095454196306869 3092.3153740414614 0.0004520573552333 0.0143050956652876 3164.4426309362034 0.0003586830612101 0.0117171203982381 3266.7058094984377 +r_3710 TAG (1-18:0, 2-18:1, 3-16:1) transport, ER membrane-lipid particle 1.4675160274880874e-05 0.0016795233187548 11444.6676376657 -6.540666399962227e-05 0.0032281967829904 -4935.577792209468 -0.0002117612544071 0.0043833631633679 -2069.955231252986 -6.424487632657344e-05 0.0035527223647674 -5529.969964776627 -0.0001516814442213 0.0068223305965934 -4497.801713066709 -4.164905437368856e-05 0.0067702540115712 -16255.48073871357 -0.0004322060108282 0.0163011340577495 -3771.612066780944 -0.000193217608835 0.0235826986759046 -12205.253350398132 -0.0009765043533375 0.0240481811476705 -2462.680382886017 +r_3711 TAG (1-18:0, 2-18:1, 3-18:0) transport, ER membrane-lipid particle 2.606304814776672e-05 0.0010670648234351 4094.167410447737 3.383302623211535e-05 0.0010179758535429 3008.82293697004 8.139178649012949e-05 0.0023569947675658 2895.8631690086936 0.0001179398165517 0.0034047350164593 2886.8410313018826 0.0001542479992395 0.0051064400989068 3310.538952908276 6.530648017236429e-05 0.0023240984573271 3558.756269198912 0.0003536648568983 0.0102267708261863 2891.655935474077 0.0001052103008077 0.0046601482627555 4429.365021273814 0.0003372649617397 0.0119149184585845 3532.8064905178253 +r_3712 TAG (1-18:0, 2-18:1, 3-18:1) transport, ER membrane-lipid particle -8.171957436030418e-06 0.0018769032625276 -22967.60937902515 -2.338497803674531e-05 0.0034661061498088 -14821.934595629891 -8.464122786742258e-05 0.0026691334655175 -3153.467326464552 1.817193712121977e-05 0.0037790359324089 20795.999387407628 -0.0001498601659649 0.0078742342461013 -5254.387779032046 -7.07621177058867e-05 0.0062734775296336 -8865.587595482311 0.0001645039596868 0.0110313260612654 6705.811873626209 0.0006555802280437 0.0223301916028368 3406.172219297838 0.0001389069007852 0.0112088177101539 8069.3022785710355 +r_3713 TAG (1-18:1, 2-18:1, 3-16:0) transport, ER membrane-lipid particle 6.602739142803107e-05 0.0016702881548752 2529.689752617021 9.582352271881366e-05 0.0027585888655619 2878.8222216133768 6.413333447386898e-05 0.0020000012322425 3118.5049844202968 0.0001971644878419 0.0043492842589843 2205.916646850883 0.0002457422871392 0.006545481230335 2663.5551034100185 0.0001902839160343 0.0055245735705441 2903.3318662350007 0.0001019039721007 0.0050966003309175 5001.37553605541 0.000434471576256 0.0137794219783575 3171.5358912772567 0.0002679938885784 0.0107772863416308 4021.467205389288 +r_3714 TAG (1-18:1, 2-18:1, 3-16:1) transport, ER membrane-lipid particle -1.1804531925249792e-05 0.0016573220406754 -14039.70992810371 -1.4820052171552328e-05 0.0037192581498889 -25096.12049158768 -0.0002690203188333 0.0045124810755793 -1677.3755585258257 -6.247733300350969e-05 0.0037162579397441 -5948.169937944309 -5.587077304297781e-05 0.0079430146054514 -14216.761596159397 -0.000238145178923 0.007589139918791 -3186.770336108157 -0.0005059238172086 0.014525585806863 -2871.101401591644 8.844676020005278e-05 0.0171805225121604 19424.70529536728 -0.0005149486558969 0.0193224413242675 -3752.3044488021737 +r_3715 TAG (1-18:1, 2-18:1, 3-18:0) transport, ER membrane-lipid particle 6.939939584553807e-05 0.0017351993309763 2500.308986606115 2.562196498710037e-05 0.0009035054080865 3526.292415673003 2.4584072489636988e-05 0.0012365818038242 5030.012030535133 7.072631542979112e-05 0.0025455252678384 3599.1204297435297 0.0001023741391267 0.0041672735178678 4070.6310728601816 6.222363203108054e-05 0.002024113903018 3252.9664967275 0.0001764433637995 0.0072563617378394 4112.572772122801 0.0001344765405172 0.0057911946709886 4306.472079601013 0.0001972831205148 0.0086102614021585 4364.418699222322 +r_3716 TAG (1-18:1, 2-18:1, 3-18:1) transport, ER membrane-lipid particle 9.224813222010662e-07 0.0017646436804835 191293.1609577815 3.287055076999839e-07 0.0027885690825028 848348.7550954212 -4.313459058747467e-05 0.0031354779774303 -7269.057002110016 8.032555081480348e-05 0.0043676075709597 5437.38265926071 -0.0001979691078091 0.0074731516426069 -3774.907976962337 1.5669097776962056e-05 0.0041174876542405 26277.758380539613 -0.0001786224519395 0.0110096519652867 -6163.643957263404 -6.509089912112113e-05 0.0176399972947866 -27100.558654078806 -0.0003529603875036 0.017619041881429 -4991.790156975173 +r_3717 episterol transport, ER membrane-lipid particle -0.000135412595045 0.0024037638905521 -1775.1405545044267 -0.0002848326150675 0.0046560870371908 -1634.6748198366658 -0.000135902373696 0.0028054726549901 -2064.3293996203747 -0.0002196642223475 0.0046799687306934 -2130.510230878322 -0.0007597788881817 0.01230488233407 -1619.5346469178069 -0.000413826499217 0.0081510579403775 -1969.680036391696 -0.0010592483817645 0.0175663713220844 -1658.3807560623534 -0.0013293537370478 0.0243311802522265 -1830.301414449672 -0.001099352737165 0.0215977859591153 -1964.5910933746336 +r_3718 fecosterol transport, ER membrane-lipid particle -0.0001474118426616 0.002529073301112 -1715.651371998497 -0.0002097718918004 0.0040733142986723 -1941.7826972487744 -0.0001440223057053 0.0030111089595161 -2090.724033870404 -0.0003584847145402 0.0058154917396071 -1622.2425960520234 -0.0006629869252106 0.0114118999189293 -1721.2858180126914 -0.0006348889503597 0.0099296486812054 -1563.9977157545995 -0.0008745796349841 0.0159828931435097 -1827.494318890678 -0.0017156690091997 0.0277935659526433 -1619.9841463364485 -0.0022122004089542 0.0307218957578889 -1388.7483084053893 +r_3719 lanosterol transport, ER membrane-lipid particle -7.467216277586224e-05 0.0017736989817035 -2375.3148640243367 -0.0001175800620694 0.0029664044551757 -2522.880497735915 -0.0001535982468767 0.0029694950368891 -1933.287063668256 -0.0001714987527342 0.0040899305422515 -2384.8164940236256 -0.0004832929412106 0.0095050686212193 -1966.7302811022007 -0.0005386466455427 0.009065643720487 -1683.04096860245 -0.0007662675877289 0.0148614381023845 -1939.4580092355468 -0.0022229608892718 0.0314167011934297 -1413.2817785975665 -0.0012025307159286 0.0227843828037089 -1894.7027715723327 +r_3720 zymosterol transport, ER membrane-lipid particle -0.0001834224166525 0.0028237071611913 -1539.455870619956 -0.0003930512671643 0.0055249142916536 -1405.6472407565182 -0.0002362556157959 0.003812919794777 -1613.895941449515 -0.0004224778362918 0.0064008083691685 -1515.0637073293508 -0.0005078327351667 0.0099628870811515 -1961.844204052652 -0.0005672191778031 0.0095129185305573 -1677.1151087310448 -0.0013133387058096 0.0191482738906605 -1457.9844335628509 -0.0017332731355872 0.0274786083956231 -1585.3593892063232 -0.0010371563865085 0.02059763307333 -1985.9717725568696 +r_3721 ergosteryl palmitoleate transport, ER membrane-lipid particle 4.396943050712786e-05 0.0013842247355665 3148.1525223351973 0.0001131551068011 0.0030038602505921 2654.639578813251 1.7254546702565076e-05 0.0007703324390612 4464.518554675905 8.3000102517251e-05 0.0028209871102707 3398.7754529393205 0.0003984625040996 0.0088488655938759 2220.7523927174534 0.0002306765017608 0.0060054861138785 2603.423438467404 0.0001952144911124 0.0074076051673811 3794.597995860474 0.0006460142896371 0.0171410273334496 2653.351111331893 0.0002740895593991 0.0107864594562745 3935.3777210342378 +r_3722 ergosteryl oleate transport, ER membrane-lipid particle 4.394766133809632e-05 0.0013773169029974 3133.9936211884283 0.000129098166919 0.0032176300560985 2492.390196458506 0.0001374916085481 0.0030361770283733 2208.263515450235 0.0002024809087633 0.0044673620786439 2206.31273631139 0.0001675001848403 0.0056841691710625 3393.5300886257983 0.0003325030970021 0.0072916093216873 2192.944783801562 0.0006004054570743 0.0132765889012539 2211.270524746548 0.0007349732708756 0.0182508938773547 2483.205117869323 0.0013216194318455 0.0239735562467457 1813.953069172749 +r_3723 episteryl palmitoleate transport, ER membrane-lipid particle 6.12542884670779e-05 0.0016345407543816 2668.451132625893 0.000181431272598 0.0037164928632125 2048.430135550658 3.562393734349769e-05 0.0011020081614684 3093.4485170533894 8.054447527686717e-05 0.0027884615161249 3462.0146279924697 0.0002794329113225 0.0074636176861472 2670.9873403319107 0.0002827460934592 0.0066850500057007 2364.329750381912 0.00031391389891 0.0095628179139617 3046.318734902932 0.0005966647738017 0.0160383993704462 2688.0084219241744 0.0002663397850331 0.0107843948385498 4049.111490124138 +r_3724 episteryl oleate transport, ER membrane-lipid particle 7.415767077801203e-05 0.0017636932814064 2378.301884219129 0.0001034006784694 0.0028099253797364 2717.511549566666 0.0001002778583525 0.0025543237634148 2547.246027566457 0.0001391189462706 0.0037162589674149 2671.2817103899542 0.0004803452480591 0.0097669295378184 2033.3144914585484 0.0001310795849578 0.0046029470509269 3511.566696223824 0.0007453336972544 0.0146503610792965 1965.6109918636364 0.000732688444646 0.0183044270617905 2498.255185480983 0.0008330121449318 0.0186748364813758 2241.8444430846766 +r_3725 fecosteryl palmitoleate transport, ER membrane-lipid particle 4.3564807042056615e-05 0.0013735412962469 3152.8690002482163 0.0001130142760364 0.0029683935421234 2626.5651086110543 1.84243965607458e-05 0.0007745075002791 4203.706198602171 0.0001698243289541 0.0039356603990826 2317.4891508888168 0.0002407849377678 0.0069474143476611 2885.319327723136 0.0001563461684382 0.0045908405198505 2936.3306857530533 0.0004109278705395 0.0108903247477675 2650.1791502893907 0.0006232507790964 0.0166400822716372 2669.8855147459203 0.0012696440987731 0.0232118761901975 1828.2191216126853 +r_3726 fecosteryl oleate transport, ER membrane-lipid particle 0.0001038469476735 0.0021233181549142 2044.661111840441 9.675748787365056e-05 0.002787403071106 2880.8138081736643 0.0001255976903768 0.0028447376874913 2264.9601907139013 0.000188660345386 0.0042735919825546 2265.2306576718183 0.0004222018628428 0.0090623760972143 2146.4557347506084 0.0004785424369088 0.0087469959939627 1827.841236080048 0.0004636516303708 0.0116076645151715 2503.5314781244983 0.001092418078011 0.0222789923957112 2039.419966051384 0.0009425561955266 0.0201346791853456 2136.178116583753 +r_3727 lanosteryl palmitoleate transport, ER membrane-lipid particle 3.562117035113186e-05 0.0012524496556142 3516.026125105883 9.05970816526504e-05 0.002626589517923 2899.198815248114 4.85869586147664e-05 0.0013301470670279 2737.662749328168 7.172826889310283e-05 0.0025738171128522 3588.288345126514 0.0002575267098863 0.0068509701521838 2660.294986569096 0.0003416660914448 0.0072279926838916 2115.51361544997 0.0005299797903891 0.0121783012768547 2297.8803150044632 0.0012562014686489 0.0237343962371072 1889.378163411473 0.0005306306942419 0.0152409601085457 2872.234922316067 +r_3728 lanosteryl oleate transport, ER membrane-lipid particle 3.905073421176902e-05 0.0012514750584958 3204.7414312601013 2.6982761487692364e-05 0.0013627110953662 5050.302564427507 0.0001050110661788 0.0026276965581214 2502.3044272734824 9.977060161753292e-05 0.0031540345334483 3161.286473483629 0.0002257660440586 0.0065753554787498 2912.464319498059 0.0001969804492059 0.0054011399090714 2741.967505325126 0.0002362875366101 0.0083568459089561 3536.7273402766104 0.0009667592508648 0.0206425997820803 2135.2368507063948 0.0006718996140615 0.0169050217975301 2516.004094025472 +r_3729 zymosteryl palmitoleate transport, ER membrane-lipid particle 7.96098629637813e-05 0.001873356156924 2353.170935335444 0.0002262134555923 0.0041597430113251 1838.857463378372 3.4421312214475154e-05 0.001090507259855 3168.116465346174 0.0002655033021555 0.0050593276831147 1905.5611143209835 0.0003563229447462 0.0083880582844822 2354.0606655167185 0.0002881758046572 0.0067987953825237 2359.252675848563 0.0002307279614213 0.0074113047219592 3212.139818816796 0.0009308002242276 0.0199305580890267 2141.228329157708 0.0003780837519831 0.0122563354209783 3241.698527559433 +r_3730 zymosteryl oleate transport, ER membrane-lipid particle 0.0001038125536888 0.0021122663138769 2034.6925673446813 0.000166837811572 0.00360755492508 2162.312542395621 0.0002018343035814 0.0036220508592637 1794.5665305610407 0.0001569745341363 0.0039022079332005 2485.885978047802 0.0001515097904205 0.0052111525513956 3439.4823838978928 0.0002790433731459 0.0066597024028961 2386.619086421404 0.0010826107443883 0.0176219851416611 1627.7304869736568 0.0008024729113595 0.0189483965812102 2361.250618305327 0.0006590726345254 0.0165255652034044 2507.396656713642 +r_3731 phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-lipid particle 8.915514652654762e-06 0.0006264107033612 7026.074520271858 6.286379357309587e-05 0.0022099648707152 3515.4812414327994 2.9451586742854084e-05 0.0013646611935241 4633.574433320786 5.272860932989367e-05 0.002164190734191 4104.3956244909605 0.0003818991992518 0.0085333153817627 2234.441810425369 0.0002193017601242 0.0058194799848648 2653.64034541645 0.0003365589774729 0.0095332613165854 2832.56782753681 0.000876748152334 0.0195686351351179 2231.956244563884 0.000426502283883 0.0130501077322104 3059.797854632416 +r_3732 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-lipid particle 8.379829735314262e-06 0.0005886005608023 7024.015754423189 4.665370494628572e-05 0.0019043304092393 4081.8417560446906 0.000140515810443 0.0029087079050233 2070.0217974415887 9.881036841291568e-05 0.0031243232611182 3161.9386824489184 0.0003419043258503 0.0080847835099259 2364.633290268486 6.458118996503595e-05 0.0032291929268695 5000.206606006763 0.0003969630486692 0.0101663130577094 2561.0225162747056 0.0002613717073164 0.0106574709902628 4077.5151601858274 0.0006756818402633 0.016868661574896 2496.5391356856626 +r_3733 phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-lipid particle 4.32034128602961e-05 0.001363805038725 3156.7067239226126 0.0001235450941332 0.0030985128165698 2508.001502048733 6.932361841976596e-05 0.0021546244020473 3108.0668481565835 8.119097289466872e-05 0.0028454176726668 3504.598567082406 0.0001180007083665 0.0048171031499181 4082.266298737074 0.0002606149718531 0.0064740668016787 2484.1499917075253 0.0002887895886623 0.0088765880160812 3073.721617595952 0.0011573035602666 0.0219567955347912 1897.237361797526 0.0001765043626164 0.0088058044404178 4989.001013846124 +r_3734 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-lipid particle 5.874378723524007e-05 0.0015687857859851 2670.556087408828 0.0001106946364813 0.0029589662355999 2673.089076088664 6.622526897703201e-05 0.0020424918946991 3084.157944919106 0.0001289620955567 0.0034578204894505 2681.26884455736 0.0004329563826258 0.0092412053947864 2134.442582585389 0.0001223552908586 0.0043263757718651 3535.912294029001 0.0007964815726487 0.0149501853496777 1877.0284038035727 0.0016985568827959 0.0268808173093406 1582.5679776524778 0.0003233366988751 0.011393324413371 3523.6719039334425 +r_3735 phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-lipid particle 5.096955749937144e-05 0.0014674969750992 2879.163655908429 0.000127342686982 0.0031727983351573 2491.543417491624 0.0001150611031556 0.0026176118193526 2274.9754239814256 0.0001021724444693 0.0031750685629028 3107.5585784345394 0.0001772196754603 0.0055007566343063 3103.919821552914 0.0003117509379794 0.0066534328764462 2134.2142286945978 0.0003329393390573 0.0095895343610748 2880.2647317750043 0.0001840098779593 0.0091340186189545 4963.874070375724 0.0011856195722732 0.0224106562259486 1890.2063317814416 +r_3736 phosphatidylcholine (1-16:1, 2-18:1) transport, ER membrane-lipid particle 6.985010184065963e-05 0.0017433997646074 2495.915852183659 8.048349095933754e-05 0.0025441135386548 3161.037758588527 0.0001268163798516 0.0028560590873783 2252.121603471077 0.0001646504169665 0.003883489235042 2358.627027242995 0.000306744735567 0.0076356747938769 2489.260257314983 0.0002656073941364 0.0063149532470016 2377.551749842155 0.0003956027289573 0.0106437763762768 2690.521474492609 0.0003673769316509 0.0129380475784784 3521.7365228501294 0.0010079170325751 0.0206138413382993 2045.192279927252 +r_3737 phosphatidylcholine (1-18:0, 2-18:1) transport, ER membrane-lipid particle 9.87720267195114e-05 0.0020321161928051 2057.380272833608 6.332267855089934e-05 0.0022117807578619 3492.873025079217 8.094711279964224e-05 0.0021953269361761 2712.0509432003146 9.431461632853718e-05 0.003003529560834 3184.585462736216 9.700297541189026e-05 0.0038553236498922 3974.438550489744 0.0002212402158562 0.0058560963476057 2646.9402612637027 0.0006294775843586 0.0133001637216432 2112.889172248073 0.0009177724544305 0.0204721337437364 2230.6328376828533 0.0004793660760501 0.013904656105364 2900.634149987047 +r_3738 phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-lipid particle 3.542246687021444e-05 0.0012482717510988 3523.954883414639 0.0001097376181058 0.0029240336654859 2664.568190887848 0.0001215563022057 0.002745305566277 2258.4641984503883 0.0001144269224944 0.00330680631389 2889.8848643339443 0.0002554743064846 0.006867397364208 2688.097076651012 0.0002856271200854 0.0064777866165049 2267.917211281592 0.0005005962285979 0.0118312547222823 2363.432652183388 0.0005438175659623 0.015695350889855 2886.14268317736 0.0001735793402065 0.0086783165430152 4999.625262250573 +r_3739 phosphatidylethanolamine (1-16:0, 2-16:1) transport, ER membrane-lipid particle 3.465864098856522e-05 0.0012158423763969 3508.0497726325875 0.0001919791523343 0.0039044613920093 2033.7944743131443 5.50178635938717e-05 0.0019263324722997 3501.285485237059 0.0001516417458479 0.0037513926550736 2473.852192941008 0.0002009848636548 0.0062335261068688 3101.490327935446 0.0001797198634236 0.0048895110241677 2720.629167539778 0.0003298161103983 0.0095048933585831 2881.8766151546824 0.0005889498966777 0.0157197858972482 2669.1210892339323 0.0006773191442288 0.016887805017622 2493.3305313329347 +r_3740 phosphatidylethanolamine (1-16:1, 2-16:1) transport, ER membrane-lipid particle 6.174668300035376e-05 0.0016456733134805 2665.201163066681 3.0788007739414155e-05 0.0015265208356453 4958.166986852871 5.5723698961289314e-05 0.001927625369029 3459.2559448865472 6.102031430563645e-05 0.0024184314383347 3963.321831187909 0.0002384792440741 0.0068609670293961 2876.966109161128 0.0001232883422502 0.0043270791912792 3509.722908347136 0.0003800667589599 0.0101502035899746 2670.63702643964 0.000523729002039 0.0151344631961275 2889.750832435352 0.0002346271813811 0.0095569261696245 4073.239133405295 +r_3741 phosphatidylethanolamine (1-18:0, 2-16:1) transport, ER membrane-lipid particle 2.5479671820088728e-05 0.0010367555622348 4068.951788529285 9.677597265875669e-05 0.0027916745325714 2884.6773180107207 3.664568997779488e-05 0.0015129376799483 4128.555584204077 0.000129723640263 0.0034756467818253 2679.2701582987584 0.0003169305230595 0.0079121110127702 2496.48122761704 0.0001907718761366 0.0054940020909958 2879.880516066866 0.0003528425263793 0.0101540925901198 2877.797269596297 0.000341080408655 0.0120486630442019 3532.499298834516 0.0005913347022654 0.0156820658151275 2651.977933148011 +r_3742 phosphatidylethanolamine (1-18:1, 2-16:1) transport, ER membrane-lipid particle 6.035202973832357e-05 0.0016139231709314 2674.182091189276 3.207580850332762e-05 0.0016036602458768 4999.594151182518 6.537830209518839e-05 0.0020409579702003 3121.7665567832446 6.924076413548442e-05 0.0024518018523152 3540.98035012691 7.957949365132876e-05 0.0039754737087484 4995.60065833881 6.415142385755535e-05 0.0028782874636875 4486.708619404344 0.0003021793221861 0.0087576955415049 2898.1782996087927 0.0003504298552316 0.0123929724502305 3536.5058841914083 0.0004226923730441 0.0133748243959991 3164.198185000497 +r_3743 phosphatidylethanolamine (1-16:0, 2-18:1) transport, ER membrane-lipid particle -4.125441538201447e-05 0.0017616282902357 -4270.156961195969 5.672852607083255e-05 0.0041260406496292 7273.308395986505 -2.569387259946532e-05 0.0020441391404257 -7955.745606321201 -7.584140124228813e-05 0.004376673509123 -5770.82363647401 -0.0004146629448018 0.0097214887842685 -2344.431521102746 2.451130028887882e-05 0.0065800201225173 26844.84317424337 2.1148874234419752e-05 0.0083584810963787 39522.10885426372 0.0002947041884818 0.0170341714982199 5780.09141504647 -0.000256953082047 0.013603152733195 -5294.0220155452935 +r_3744 phosphatidylethanolamine (1-16:1, 2-18:1) transport, ER membrane-lipid particle 4.668661735915323e-05 0.0023760713881311 5089.40574951569 4.60029445922657e-05 0.0029599928940828 6434.355279467269 -4.8371170014333065e-06 0.0029511617128167 -61010.75727426745 0.0001064397196894 0.0042235833847786 3968.051961336309 -0.0002843174372053 0.0102168806933285 -3593.4766413749016 -3.98749736865132e-05 0.0057131806770863 -14327.735290816434 0.0001081411925621 0.0118256275228833 10935.358897660708 0.0001604627651684 0.0179239645485014 11170.170556197574 0.0001481662553869 0.022048099453892 14880.648361067577 +r_3745 phosphatidylethanolamine (1-18:0, 2-18:1) transport, ER membrane-lipid particle 3.537925281893335e-05 0.0015317300530219 4329.458456517238 -6.444258769154987e-05 0.0022763587912214 -3532.3826568186983 -0.0002269086021019 0.0039012970993875 -1719.325342119104 4.489873137436405e-05 0.0018807944108766 4188.97005172525 -0.0001649138812044 0.0098920936883337 -5998.339021606848 1.2668656167856728e-05 0.0065762703139706 51909.77027741998 -7.295842390700091e-05 0.011014266341416 -15096.634153522547 7.101282742349779e-05 0.0167067645922673 23526.40388846023 0.0002992047794936 0.0224209450022482 7493.511647839031 +r_3746 phosphatidylethanolamine (1-18:1, 2-18:1) transport, ER membrane-lipid particle 5.778142782938342e-06 0.0013005832891661 22508.673427151884 -1.770451685963315e-05 0.0033752912702044 -19064.57711873623 4.862454495432576e-05 0.002953627649797 6074.355354012016 -6.019053485464932e-06 0.0043542574062071 -72341.23133682035 -0.0005184466258641 0.0118435711713125 -2284.4340343755293 -3.260497345148137e-06 0.0064094557624414 -196579.08238996693 0.0001224866934371 0.0156966343374977 12814.97107728376 -0.0001211798018597 0.019317248337379 -15940.980296157522 2.827004592455028e-06 0.0174612814622569 617660.1732045026 +r_3747 1-acylglycerophosphocholine (16:0) transport, ER membrane-lipid particle -5.988507215202589e-05 0.0015968779535073 -2666.5709769097507 -0.0001902064805551 0.003876794138573 -2038.2029714543555 -0.0001445126898984 0.0029888478483306 -2068.225185227725 -0.0001549010537992 0.003890787801216 -2511.789110395056 -0.0005591188747122 0.0102332304377675 -1830.2423510626345 -0.0005310526981036 0.008926761230085 -1680.955818878545 -0.0006694983165303 0.0136522214976294 -2039.1718934234284 -0.0010607580302933 0.0216165040030711 -2037.8355275889448 -0.0016121218561562 0.0259478212829614 -1609.5446621404046 +r_3748 1-acylglycerophosphocholine (16:1) transport, ER membrane-lipid particle -7.822993157597223e-05 0.0018411006228498 -2353.4478245860746 -0.0001271371959056 0.0031777944335308 -2499.5001745121376 -0.0002673321902946 0.0040908126880593 -1530.2357278970967 -0.0002634607853794 0.0050159612553742 -1903.873947748656 -0.0006486490614174 0.0111556772097227 -1719.8324754136397 -0.0003301885841015 0.0071145027397009 -2154.6785934652285 -0.0007925657776265 0.0148433245460773 -1872.8192618317323 -0.0006287486389673 0.0167744186055601 -2667.905354532436 -0.0016835988728385 0.0266545317318567 -1583.1877867034518 +r_3749 1-acylglycerophosphocholine (18:0) transport, ER membrane-lipid particle -0.0001419754395798 0.002449645076743 -1725.400593224472 -0.0001868677726841 0.003821343991805 -2044.945437576141 -0.0001502707312194 0.0030989322272046 -2062.2327462290746 -0.0001755055892232 0.0041420889093685 -2360.0894579491446 -0.0002150036837784 0.006247843748998 -2905.924047067331 -0.0004818551877093 0.0088142806582142 -1829.238510456844 -0.000918267173021 0.0161226217654149 -1755.7658859101691 -0.0020750760146971 0.029989725611344 -1445.23503712322 -0.0006558704386666 0.0164533400558375 -2508.626564918368 +r_3750 1-acylglycerophosphocholine (18:1) transport, ER membrane-lipid particle -9.416625410545242e-05 0.0020063627598824 -2130.660053266616 -0.0002204322545872 0.0041637992805835 -1888.9246895290585 -0.0001877815711827 0.0034602739846856 -1842.712233628788 -0.0002433890180511 0.0048108362665807 -1976.603671398816 -0.0006884306891104 0.0115039019870419 -1671.0327080140505 -0.000407982410944 0.0078107867201821 -1914.4910443831875 -0.0012970778012466 0.0191683564904707 -1477.8108508254122 -0.0022423744487582 0.0311071510475599 -1387.2415940515991 -0.0004969160390817 0.0143950732494104 -2896.8823940581324 +r_3751 1-acylglycerophosphoethanolamine (16:0) transport, ER membrane-lipid particle 6.59577439344924e-06 0.0021400278388575 32445.43720268761 -0.0002487076784051 0.0056824063335157 -2284.7731802868443 -2.932399099440743e-05 0.0028068253330282 -9571.77122842382 -7.580034460566853e-05 0.0057675892748033 -7608.922234862864 0.000213678081147 0.0116159030529007 5436.169676620204 -0.0002042311637125 0.0082360046173799 -4032.68750354419 -0.0003509649846327 0.0126300515646856 -3598.664287806544 -0.0008836540851596 0.023156226203501 -2620.5080237159373 -0.0004203660621818 0.0216626609569297 -5153.284935633149 +r_3752 1-acylglycerophosphoethanolamine (16:1) transport, ER membrane-lipid particle -0.0001084333003595 0.0028960047822241 -2670.7706697320896 -7.679095233167896e-05 0.0033373689633163 -4346.044503916867 -5.0886581959856966e-05 0.003546114279379 -6968.662745272321 -0.0001674600339951 0.0049209226294122 -2938.565406929397 4.583819313118791e-05 0.0123525220887044 26948.09992477636 -8.341336856375898e-05 0.0072008735058607 -8632.757110578197 -0.0004882079515221 0.0155995338860533 -3195.264197851812 -0.0006841917672074 0.0234600778252873 -3428.8746152327726 -0.0003827934367681 0.024056273166468 -6284.40063381746 +r_3753 1-acylglycerophosphoethanolamine (18:0) transport, ER membrane-lipid particle -6.085892463902055e-05 0.0018520344565602 -3043.160009062664 -3.233338496720782e-05 0.0036033770976328 -11144.447453575904 0.0001902629121241 0.0041881767675749 2201.257576065255 -0.0001746223716373 0.0039742675323006 -2275.9211749534243 -0.000152016641855 0.0127440971330496 -8383.356570393182 -0.0002034405323045 0.0086205353814459 -4237.373587157746 -0.0002798841024723 0.0150174286355499 -5365.588292758729 -0.0004120932360785 0.0206041508086938 -4999.876000091878 -0.0008905394817591 0.0274532288644402 -3082.763810786882 +r_3754 1-acylglycerophosphoethanolamine (18:1) transport, ER membrane-lipid particle -6.613017252126173e-05 0.002072575042927 -3134.083828770768 -1.4371291643703504e-05 0.0037407869337023 -26029.58054463586 -0.0001140028470495 0.0036138538865648 -3169.9681017572866 -6.32217106500209e-05 0.0050080745964996 -7921.447466398076 0.0004388671322128 0.0125097454236968 2850.4630457562016 -6.0890926512406985e-05 0.0070366137186 -11556.095664214034 -0.0004246660156233 0.0180594215515026 -4252.617559941309 -0.0002292500533719 0.0229539679083353 -10012.633615877356 -0.0004255193776366 0.0220202109366615 -5174.90203594574 +r_3755 phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane 9.495464338095811e-05 0.0010674617489632 1124.1806729562838 0.0001507680445498 0.0017618474346535 1168.5814722303933 0.0001423773327874 0.0011946610855444 839.0809563259252 0.0002284708213602 0.0019246375616779 842.3997209880617 0.000485757124705 0.0043603426422824 897.638432978201 0.0004856432070841 0.0032213564816388 663.3175208977661 0.000663426564647 0.0064271071967324 968.7744716933458 0.000730924336496 0.0099732852375988 1364.4757384066536 0.0011365532587841 0.0099680746268904 877.0442167887722 +r_3756 phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane 6.736379311047755e-05 0.0009794431396292 1453.9607917014248 8.722046722998271e-05 0.0015527708993591 1780.282711929112 0.0001145294639005 0.0013683644758077 1194.7706984781175 0.0001444710702265 0.0020864126136819 1444.1732939406777 0.0002444981961084 0.0038174951804791 1561.3592415976077 0.0003277056114723 0.0042367599998622 1292.8554933271962 0.0003175614078524 0.0055230069853337 1739.193380796576 0.0005418929332896 0.0092893125502532 1714.2339343420374 0.0005654449109855 0.0086291357571932 1526.0789494335424 +r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane 4.847696915896e-05 0.0008180881476631 1687.5810552028256 0.0001345198220589 0.0017727051890792 1317.8022108169205 7.780395090748444e-05 0.0012352652946597 1587.6639685414216 0.0001240822520199 0.0019505084384265 1571.9479673154844 0.0001874466350137 0.0031791521882749 1696.0305465292436 0.0002861499598272 0.0034356029023556 1200.63022354767 0.0004696635733348 0.0068603042011077 1460.6847519378248 0.0004140932453629 0.0077824463299956 1879.39465739776 0.0006658086438205 0.0099227856811249 1490.3359656291298 +r_3758 phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane 5.599463073443212e-05 0.0009394617152164 1677.7710700015352 8.224319096178093e-05 0.0015443348966355 1877.7662668186308 0.0001093504637543 0.00162055616319 1481.9838046872485 0.0001172260269797 0.0020612918280937 1758.390931776887 0.000300090596532 0.004393724174082 1464.1325735818864 0.0002089651212027 0.0034314822003037 1642.1315579140994 0.0004100125244061 0.006744441129277 1644.935392899377 0.0002133355538219 0.0060561496863967 2838.7906178318854 0.0004585382050287 0.0085244362394056 1859.0460175225207 +r_3759 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane 5.236578011949228e-05 0.0010249704919274 1957.3287929418268 8.051001170339299e-05 0.0017133983719608 2128.1805029083816 9.34012219043938e-05 0.0017015817287902 1821.7981457801468 0.000118771785158 0.0023266367582085 1958.91368906634 6.252801962731268e-05 0.0023078763568145 3690.947467343906 0.0001652166948582 0.0035112955935244 2125.266817943368 0.0005185828024459 0.0083994347537237 1619.6901852715523 0.000337344062811 0.0081260894601414 2408.8431829593897 0.0005200860958881 0.0101876812620228 1958.8451494026187 +r_3760 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane 5.254803379808145e-05 0.0010218497331569 1944.6012710645907 0.0001179094349285 0.0020637890297327 1750.3171234633155 6.35417705851757e-05 0.0013870688311852 2182.924426580013 9.536202261811258e-05 0.0020579161061945 2158.0038360088784 0.0002225675287156 0.0044819042014068 2013.7278008474864 0.0001839338394386 0.0036766544628147 1998.9005144652688 0.0003099879659908 0.0064592360774181 2083.705429264533 0.0004614106025603 0.0097223965034603 2107.1029684864043 0.0002449093444222 0.0069562843748639 2840.3507392802003 +r_3761 phosphatidate (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane 4.670021003548938e-05 0.0009564670269543 2048.100053998627 9.521862590359636e-05 0.001865163596713 1958.8222146803944 5.473861635508189e-05 0.0012885104579609 2353.933189692993 0.0001190385096681 0.002329734257015 1957.126532842766 0.0001616885768872 0.0038026363047164 2351.827431425882 0.000148987464211 0.0033283903245078 2234.006963023577 0.0002155786128684 0.0053850641663843 2497.958445289355 0.0002495757201236 0.0072011329453566 2885.3499618426026 0.0003609316877739 0.0085000814820452 2355.038853603819 +r_3762 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane 5.2380337500109765e-05 0.0010252502012632 1957.3188150249748 0.0001221965019381 0.0020980353999074 1716.935727807247 9.202526857443068e-05 0.0016784096570845 1823.857385134435 0.0001555949731497 0.0026642117532481 1712.273667532656 0.0003639098835194 0.0057443050565641 1578.4965775070832 0.0001635822953167 0.0034804325009797 2127.633980339694 0.0002952244607753 0.0062996611080757 2133.854725834921 0.0004993986468873 0.0101828166482908 2039.0156664938256 0.0002247559615726 0.0065404471876404 2910.021670560628 +r_3763 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane 6.640330017407991e-05 0.0011415222159249 1719.0745233029108 9.763726399713722e-05 0.0018713130197401 1916.597150648368 6.195895162157319e-05 0.0013842668840044 2234.16769938124 0.0001093389017337 0.002229553394094 2039.1218118526992 0.0002375154988664 0.0046525419273971 1958.8371915105693 7.847644683144275e-05 0.0023693201137269 3019.148049370729 0.0003581830971794 0.0069429672479605 1938.3849496623648 0.0004589685251061 0.0097754875668542 2129.8819052117547 0.0005210749941658 0.0101967048428656 1956.8593690027708 +r_3764 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane 3.588212530193559e-05 0.0008445754571803 2353.7498129600367 0.0001023524952802 0.0019319145020389 1887.510897266704 9.276026017453898e-05 0.0016888245888786 1820.6337344256235 6.913143764091042e-05 0.0017357550065017 2510.804151821321 0.0002908221501072 0.0051338560893135 1765.2906036970037 0.0002385305078244 0.004210506237611 1765.185625945102 0.000518842791608 0.0084035872067713 1619.6788974798046 0.0006254050649566 0.0114023757020397 1823.198490218494 0.0004009553908843 0.0089576194528606 2234.0688407018424 +r_3765 phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane 5.015527048541705e-05 0.0002275924390644 453.7757186069892 0.0001329818007281 0.0003608192503947 271.32979732491617 8.774242942920747e-05 0.0004693287342931 534.8937080341159 0.0002256763424564 0.0008580979292797 380.23388714087525 0.0003036411741744 0.0011843729993762 390.0567841618984 0.000413034199867 0.0013997975278965 338.9059618664143 0.0002984349840691 0.0014651118233066 490.9316606686074 0.0005265770788919 0.0020903173745733 396.9632288157583 0.0006350422580295 0.0026096556771432 410.9420505716392 +r_3766 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane 2.52305553753852e-05 0.0001726533627096 684.3026645306649 4.415628237642885e-05 0.0002945079825064 666.967341126655 9.664841226822231e-05 0.0005156411594865 533.5226387946934 0.0001016870071039 0.0005898071558865 580.0221411605241 0.0001984259457258 0.0012776779886986 643.9067149333833 0.0001865873276228 0.0010725465489366 574.8228256446776 0.0002387473741768 0.0016157600460187 676.7655776696568 0.0002858956831095 0.0025740396452164 900.3422567351531 0.0002679135390478 0.0020667431980151 771.4217076749134 +r_3767 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane 3.724832708699908e-05 0.0002164538616654 581.1102902953195 4.896971739284922e-05 0.0002533502403921 517.3610424575683 7.981169523490686e-05 0.0004187979690896 524.732581931789 0.0002281396428301 0.0007624782951997 334.2156083620712 0.0002203302817565 0.000999360270125 453.5737267513244 0.0001966275924112 0.0009828570762529 499.8571483279632 0.0005193805749543 0.0019879976177859 382.76318246226657 0.0003713424787544 0.0018975241006225 510.99031465158544 0.0004570272788084 0.0017997871609649 393.80300573246313 +r_3768 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane 7.40571956313605e-06 0.0001921266978592 2594.3015559974674 7.202415538656133e-06 0.0002158167845869 2996.450058020332 1.464536674337826e-05 0.0003715789668058 2537.177616080273 1.1424766795543322e-05 0.000397272628236 3477.2931066835577 4.912891980942719e-05 0.0010763679323717 2190.904942642738 2.3471632731148698e-05 0.0006681247956245 2846.520322116012 4.181260400447789e-05 0.0012389975054835 2963.215362886486 6.214023955364995e-05 0.0017887531100288 2878.5745321829463 0.0001458184247431 0.0028656329249764 1965.206337967908 +r_3769 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane 9.261950719504068e-05 0.0002432563625472 262.6405278048021 0.0001000115654629 0.0003257908057377 325.75313088000064 0.000206634413731 0.0006144927324486 297.38160326401925 0.0003117503669944 0.000936379731481 300.3620302066483 0.0004805443092129 0.0013129420931641 273.219777654757 0.0003909395940042 0.0014998770514331 383.6595408693223 0.0005975437881463 0.0021654664298329 362.3946014986888 0.0006707638777483 0.0027189307594172 405.34841687424415 0.0007098992668366 0.0029676388162029 418.0366081271015 +r_3770 phosphatidyl-L-serine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane 8.883361628032877e-06 0.0001702436676434 1916.432931270756 1.894567109575543e-05 0.0002434698250657 1285.0947524382316 3.72793078960887e-05 0.000434972386338 1166.793084116412 3.239839144735387e-05 0.0004349008419769 1342.3531926999938 8.369310428120517e-05 0.0012035171868279 1438.0123633414175 6.99958609959758e-05 0.0010321435804298 1474.578018961987 0.0001452226455756 0.0015683219686034 1079.9431193303053 0.0001566925511824 0.0026781165752093 1709.1537249212265 6.598481973301203e-05 0.0010290539773409 1559.5313914696642 +r_3771 phosphatidyl-L-serine (1-18:0, 2-18:1) transport, ER membrane-mitochondrial membrane 4.813089625324781e-06 8.243433636126044e-05 1712.7114344083686 1.4252730047680373e-05 0.0001955295447336 1371.8743291954502 2.4218328854761565e-05 0.0003795179853917 1567.0692543146808 4.334234256756232e-05 0.000562814969065 1298.5338025689184 5.061163856836597e-05 0.0008029638859773 1586.5202326786457 6.764970125578668e-05 0.0008473386875128 1252.5386982997006 0.0001156198318106 0.0017765140861384 1536.5132938846834 8.397015908239272e-05 0.0015421939395289 1836.5976156073275 0.0001398382299362 0.0024475955083655 1750.3049841817858 +r_3772 phosphatidyl-L-serine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane 6.594939788700334e-06 0.0001767676622946 2680.352936618156 1.2342595912322376e-05 0.0002683522135384 2174.1958939979386 1.8614255796507577e-05 0.000398233461526 2139.4003922559423 2.171602905591568e-05 0.0005201890151622 2395.41498965049 5.24952169338462e-05 0.0010956765433315 2087.1930955391467 4.644311034668739e-05 0.0010247049195547 2206.3658353318533 7.902412948213361e-05 0.0016871277068528 2134.952599805956 8.956883596715579e-05 0.0022594007999059 2522.530046873058 0.0001038573322892 0.002350716424115 2263.4092098266583 +r_3773 phosphatidylethanolamine (1-16:0, 2-16:1) transport, mitochondrial membrane-ER membrane 5.015527048541705e-05 0.0002275924390644 453.7757186069892 0.0001329818007281 0.0003608192503947 271.3297973249161 8.774242942920747e-05 0.0004693287342931 534.8937080341159 0.0002256763424564 0.0008580979292797 380.2338871408752 0.0003036411741744 0.0011843729993762 390.0567841618984 0.000413034199867 0.0013997975278965 338.9059618664143 0.0002984349840691 0.0014651118233066 490.9316606686075 0.0005265770788919 0.0020903173745733 396.9632288157583 0.0006350422580295 0.0026096556771432 410.9420505716392 +r_3774 phosphatidylethanolamine (1-16:1, 2-16:1) transport, mitochondrial membrane-ER membrane 2.52305553753852e-05 0.0001726533627096 684.3026645306649 4.415628237642885e-05 0.0002945079825064 666.967341126655 9.66484122682223e-05 0.0005156411594865 533.5226387946934 0.0001016870071039 0.0005898071558865 580.0221411605241 0.0001984259457258 0.0012776779886986 643.9067149333833 0.0001865873276228 0.0010725465489366 574.8228256446776 0.0002387473741768 0.0016157600460187 676.7655776696568 0.0002858956831095 0.0025740396452164 900.342256735153 0.0002679135390478 0.0020667431980151 771.4217076749134 +r_3775 phosphatidylethanolamine (1-18:0, 2-16:1) transport, mitochondrial membrane-ER membrane 3.724832708699908e-05 0.0002164538616654 581.1102902953195 4.896971739284922e-05 0.0002533502403921 517.3610424575683 7.981169523490686e-05 0.0004187979690896 524.732581931789 0.0002281396428301 0.0007624782951997 334.21560836207124 0.0002203302817565 0.000999360270125 453.5737267513244 0.0001966275924112 0.0009828570762529 499.8571483279632 0.0005193805749543 0.0019879976177859 382.76318246226657 0.0003713424787544 0.0018975241006225 510.9903146515805 0.0004570272788084 0.0017997871609649 393.80300573246313 +r_3776 phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane 7.40571956313605e-06 0.0001921266978592 2594.3015559974674 7.202415538656133e-06 0.0002158167845869 2996.450058020332 1.464536674337826e-05 0.0003715789668058 2537.177616080273 1.1424766795543318e-05 0.000397272628236 3477.2931066835577 4.912891980942719e-05 0.0010763679323717 2190.904942642738 2.3471632731148698e-05 0.0006681247956245 2846.520322116012 4.1812604004477895e-05 0.0012389975054835 2963.2153628864858 6.214023955364995e-05 0.0017887531100288 2878.5745321829463 0.0001458184247431 0.0028656329249764 1965.206337967908 +r_3777 phosphatidylethanolamine (1-16:0, 2-18:1) transport, mitochondrial membrane-ER membrane 9.261950719504068e-05 0.0002432563625472 262.6405278048021 0.0001000115654629 0.0003257908057377 325.75313088000064 0.000206634413731 0.0006144927324486 297.38160326401925 0.0003117503669944 0.000936379731481 300.3620302066483 0.0004805443092129 0.0013129420931641 273.219777654757 0.0003909395940042 0.0014998770514331 383.6595408693223 0.0005975437881463 0.0021654664298329 362.3946014986888 0.0006707638777483 0.0027189307594172 405.34841687424415 0.0007098992668366 0.0029676388162029 418.0366081271015 +r_3778 phosphatidylethanolamine (1-16:1, 2-18:1) transport, mitochondrial membrane-ER membrane 8.883361628032877e-06 0.0001702436676434 1916.432931270756 1.894567109575543e-05 0.0002434698250657 1285.0947524382316 3.72793078960887e-05 0.000434972386338 1166.793084116412 3.239839144735387e-05 0.0004349008419769 1342.3531926999938 8.369310428120517e-05 0.0012035171868279 1438.0123633414175 6.99958609959758e-05 0.0010321435804298 1474.578018961987 0.0001452226455756 0.0015683219686034 1079.9431193303053 0.0001566925511824 0.0026781165752093 1709.1537249212265 6.598481973301203e-05 0.0010290539773409 1559.5313914696642 +r_3779 phosphatidylethanolamine (1-18:0, 2-18:1) transport, mitochondrial membrane-ER membrane 4.813089625324781e-06 8.243433636126044e-05 1712.7114344083686 1.4252730047680373e-05 0.0001955295447336 1371.8743291954502 2.4218328854761565e-05 0.0003795179853917 1567.0692543146808 4.334234256756232e-05 0.000562814969065 1298.5338025689186 5.061163856836598e-05 0.0008029638859773 1586.5202326786457 6.764970125578668e-05 0.0008473386875128 1252.5386982997006 0.0001156198318106 0.0017765140861384 1536.5132938846834 8.397015908239272e-05 0.0015421939395289 1836.5976156073275 0.0001398382299362 0.0024475955083655 1750.3049841817858 +r_3780 phosphatidylethanolamine (1-18:1, 2-18:1) transport, mitochondrial membrane-ER membrane 6.594939788700334e-06 0.0001767676622946 2680.352936618156 1.2342595912322376e-05 0.0002683522135384 2174.1958939979386 1.8614255796507577e-05 0.000398233461526 2139.4003922559423 2.1716029055915687e-05 0.0005201890151622 2395.4149896504896 5.24952169338462e-05 0.0010956765433315 2087.1930955391467 4.644311034668739e-05 0.0010247049195547 2206.3658353318533 7.902412948213361e-05 0.0016871277068528 2134.952599805956 8.956883596715579e-05 0.0022594007999059 2522.530046873058 0.0001038573322892 0.002350716424115 2263.4092098266583 +r_3781 phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane 7.53928516493456e-09 2.2190617163533525e-08 294.33317188667627 -4.800014465109235 69.12243046261767 -1440.0462949655848 -0.7999999777915621 69.28431914980388 -8660.540134146819 1.2457914151245193e-08 2.6123516870940493e-08 209.6941474615106 3.199998579341146 56.4835839124856 1765.1127808973938 1.7953625615829302e-08 2.4185969566342632e-08 134.71356752041444 7.800000673223202 87.9812580102583 1127.964748929973 -0.8000831001280316 28.27575411332908 -3534.1021587388 5.000000218931493 70.54070139511774 1410.813966128033 +r_3782 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane 4.799997309730707 69.12242792747938 1440.051388932077 6.000014390589348 77.2346259103312 1287.2406778135223 0.7999999942290675 69.28431915070928 8660.539956312898 -1.3300608953459398e-09 2.4601023930483133e-08 -1849.616360917413 -3.19999856682522 56.48358391308686 -1765.112787819943 -1.1663872884133022e-08 2.3612197575386242e-08 -202.438742345239 -2.800003467655384 77.41674483454977 -2764.8803199295894 4.000000501607702 63.12520553711028 1578.1299405272237 6.355939124337696e-09 2.0149192564307642e-08 317.01361781697733 +r_3783 phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane 3.2665546321708356e-09 2.3194012418630003e-08 710.0451402282561 -1.1999998988469518 34.62367389435042 -2885.306401077149 -3.771265711593596e-09 2.2336228744122023e-08 -592.2740653212569 8.138746397699597e-09 2.2058595703451865e-08 271.0318595218385 8.564266168023203e-09 2.3701670434172506e-08 276.7507451212636 9.504236162440936e-09 2.4205998086015545e-08 254.68641216717 -6.599996258443952 122.30863190617627 -1853.1621400496424 -7.9999128900045715 89.0921648635434 -1113.6641872045743 4.399998148697571 66.19299238611983 1504.386823565219 +r_3784 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane -4.799997304673326 69.1224279256118 -1440.0513904104384 -8.16585345745666e-09 1.993832977613424e-08 -244.1671269269169 1.2484188646848664e-08 2.18023522345813e-08 174.63972110101673 2.712794327928893e-09 2.3665307588568112e-08 872.3590780520245 -1.3203107746371283e-09 2.3959642816007066e-08 -1814.697211919072 1.8375553786729995e-10 2.367867176131949e-08 12885.963621090525 1.5999990794374612 59.984630234749055 3749.041546688819 4.799995509862146 69.12239817833502 1440.0513091379992 -9.399998357063312 96.50645208475656 -1026.6645633213334 +r_3785 phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane -7.539285089201351e-09 2.2190617163670843e-08 -294.33317484511684 4.800014465109235 69.12243046261767 1440.0462949655848 0.7999999777915612 69.28431914980386 8660.540134146828 -1.2457913942333897e-08 2.6123516567362372e-08 -209.69414854111864 -3.199998579341146 56.48358391248559 -1765.1127808973936 -1.795362564494545e-08 2.418596955350501e-08 -134.71356723043945 -7.800000673223202 87.9812580102583 -1127.964748929973 0.8000831001280316 28.27575411332908 3534.1021587388 -5.000000218931491 70.54070139511774 -1410.8139661280338 +r_3786 phosphatidylcholine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane -4.799997309730707 69.1224279274794 -1440.051388932077 -6.000014390589347 77.2346259103312 -1287.2406778135226 -0.7999999942290673 69.2843191507093 -8660.539956312903 1.330060969545244e-09 2.4601023998995492e-08 1849.6162628850568 3.19999856682522 56.48358391308687 1765.1127878199432 1.1663872838147094e-08 2.3612197500367607e-08 202.4387425002021 2.800003467655384 77.41674483454977 2764.8803199295894 -4.000000501607703 63.12520553711028 -1578.1299405272232 -6.355939157679325e-09 2.0149192567803625e-08 -317.0136162090085 +r_3787 phosphatidylcholine (1-18:0, 2-18:1) transport, ER membrane-mitochondrial membrane -3.266554630973157e-09 2.319401259456201e-08 -710.0451458744518 1.1999998988469518 34.62367389435042 2885.306401077149 3.771265635218564e-09 2.2336228747429243e-08 592.2740774035859 -8.138746426927081e-09 2.205859565679896e-08 -271.0318579753019 -8.564266222087681e-09 2.37016704959702e-08 -276.75074409576825 -9.504236133726204e-09 2.4205998103217064e-08 -254.68641311763088 6.599996258443952 122.30863190617627 1853.1621400496424 7.999912890004571 89.0921648635434 1113.6641872045748 -4.399998148697572 66.19299238611984 -1504.3868235652192 +r_3788 phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane 4.799997304673326 69.1224279256118 1440.0513904104384 8.165853980968392e-09 1.9938330178689887e-08 244.16711620314072 -1.2484188737676016e-08 2.1802352288369242e-08 -174.639720261293 -2.7127942389150004e-09 2.3665307644297053e-08 -872.3591087307136 1.3203107493757936e-09 2.395964278541332e-08 1814.6972443222755 -1.8375556700393092e-10 2.3678671751955588e-08 -12885.961572771856 -1.5999990794374614 59.984630234749055 -3749.041546688818 -4.799995509862147 69.12239817833502 -1440.051309137999 9.399998357063314 96.50645208475656 1026.6645633213334 +r_3789 diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane -0.000245082679389 0.0031695343359434 -1293.2510546416158 -0.0005399225232538 0.0068265044386261 -1264.3488916679212 -0.0004867540224901 0.005693226360598 -1169.6310862461448 -0.0005404999413829 0.0070829780338531 -1310.4493620721855 -0.0011021767673221 0.0143732466240987 -1304.0781706023272 -0.0010103188199991 0.0118273468613415 -1170.6549088486524 -0.0023656337577283 0.0274793723490828 -1161.60721241442 -0.0030804718894243 0.0367171758138761 -1191.933480708922 -0.0014139224124809 0.0240748783354105 -1702.7015148000796 +r_3790 diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane -0.0002950863315147 0.003352742975477 -1136.1905372799993 -0.0007061527277235 0.0075425610127642 -1068.120353663419 -0.0004671504898449 0.0053440300889166 -1143.9632848700653 -0.0009138325299488 0.0094435510479472 -1033.4006219362136 -0.0015831129542017 0.0166124072743964 -1049.350725752426 -0.0012922516952479 0.0148183204351114 -1146.7054359149213 -0.0020778129899001 0.0223297670532241 -1074.6764584572672 -0.0024102774047776 0.0330644725413733 -1371.8119116012576 -0.0033821424354846 0.0350815691091603 -1037.258772460097 +r_3791 diglyceride (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane -0.0002884518395543 0.0037310091017805 -1293.4599784648535 -0.0005544554292513 0.0069030891413055 -1245.0214710001935 -0.0003063304697975 0.004189471086326 -1367.631202046176 -0.0006450091460338 0.0080263207662471 -1244.3731713884072 -0.0015490617115919 0.0182097563186455 -1175.5345950634644 -0.0005128549553823 0.0077583166552749 -1512.7701456039129 -0.0013574958797043 0.0186683693476088 -1375.2063359245171 -0.002826793687967 0.0350202393417924 -1238.867890885147 -0.0028775830619212 0.0332634340129715 -1155.9504381695356 +r_3792 diglyceride (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane -0.000252830159016 0.0034114545627006 -1349.3068137034518 -0.0004335419167683 0.0060953216666845 -1405.9359501197423 -0.000326807913795 0.0049964593004667 -1528.867291628743 -0.0005480984224453 0.0078776738306348 -1437.2735822680727 -0.0016970506899403 0.0189830505429064 -1118.5906617540782 -0.0009609873601956 0.0111491190797388 -1160.1733322973662 -0.0020128468015626 0.026074302027364 -1295.3942648353377 -0.0030456924224324 0.0379583539072964 -1246.2963636026288 -0.0032578385871229 0.0399270373777483 -1225.5683119343514 +r_3793 diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane -0.0002717807113506 0.0033877907721103 -1246.5162649968147 -0.0003963566217414 0.0055355227120909 -1396.601547305941 -0.0003904828631088 0.0052521608232383 -1345.0425919907227 -0.0005641177443534 0.0069644871112448 -1234.5804011584314 -0.0011446354526553 0.0139896954400577 -1222.1965873592517 -0.0009415901349059 0.011879497631112 -1261.6421084634887 -0.0017822145931788 0.0220236233717463 -1235.7447557683563 -0.0030279299866015 0.0348511175335275 -1150.9882225726053 -0.0037289531478668 0.0416970639771871 -1118.1975831753216 +r_3794 diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane -0.0002299782995707 0.0030946745224913 -1345.637622448736 -0.000479642892736 0.0064427046161629 -1343.229455441652 -0.0004589213996665 0.0057527046273297 -1253.5272121784103 -0.0004548415307319 0.0070058022511326 -1540.2732111684804 -0.0016531850167854 0.0191404027865811 -1157.789514920687 -0.0011148129939208 0.013687882744621 -1227.8187300706556 -0.0017341420130114 0.0240087273235225 -1384.4729637700896 -0.0030707765868802 0.0380626967974063 -1239.5137099855078 -0.0024637321579362 0.0305951329487949 -1241.8205790041266 +r_3795 diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane -0.0002342621129998 0.003413171932614 -1456.9884514855844 -0.0004632863316154 0.0054094165987389 -1167.6184315381836 -0.0004396334006489 0.0055830698605964 -1269.9376008181114 -0.0005300821660911 0.0070765839700677 -1334.9975575014416 -0.0011052501556235 0.0152466289685606 -1379.4731347455302 -0.0011772671154869 0.0138731927064303 -1178.4235305588984 -0.0016098903017574 0.0213025576608759 -1323.230386419547 -0.0029243410987692 0.0374472645952054 -1280.5368228407178 -0.0031303213229078 0.0398221749317347 -1272.1433624182448 +r_3796 diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane -0.0002664903878455 0.003364088998789 -1262.3678572370998 -0.0005650452364183 0.0069284903216031 -1226.1832991496874 -0.0005778004347088 0.0066811099011771 -1156.3006013562028 -0.0007568882011624 0.0090082964786857 -1190.1753079055436 -0.0005868623620767 0.0106214232761332 -1809.866156443596 -0.0007196818770407 0.0106862783137544 -1484.8613887145727 -0.0024646192785705 0.0283022545075323 -1148.3418454775394 -0.0024777598046174 0.0324984419787495 -1311.60582709377 -0.0020488408818375 0.0309773107262457 -1511.9432163254598 +r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane 7.419289770086378e-05 0.0023334394272341 3145.098115243123 0.0002418829277528 0.0056741262765219 2345.8151136317574 0.0001787543084742 0.0044331554624224 2480.0271950153706 0.0001806183323827 0.005352902354606 2963.65395693251 0.0003386862034758 0.0106228368971235 3136.4835024587514 0.0002280665723567 0.0077984241569642 3419.3630729741244 0.0010362867667198 0.0225905675509944 2179.9532983036925 0.0010539064893428 0.0280836442860889 2664.7187933723826 0.0004425123731984 0.0180155977705881 4071.207690842813 +r_3798 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane 7.744767068146314e-05 0.0023396799843544 3020.981733559729 0.0002842774790295 0.0060371531924334 2123.683245343155 0.0001505904633692 0.0039574630659762 2627.963934391658 0.000357739791701 0.0075100184090979 2099.296355428477 0.0004266954058222 0.0116484300091378 2729.91690329823 0.0005796180867464 0.0122853893481107 2119.566250437781 0.0004310814735451 0.0142914127689314 3315.2463387954967 0.00095406085691 0.0264970721219735 2777.29370511972 0.0007806150537026 0.0232391019155348 2977.0245661168133 +r_3799 phosphatidate (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane 0.0001359799956568 0.0031355005348447 2305.854269003322 0.000244072256759 0.005702904297712 2336.563923093218 6.878261124106274e-05 0.0027893232508547 4055.273855595513 0.0002429197327616 0.006295533583983 2591.6106165658584 0.0006714481767862 0.0149886758972372 2232.2908029890764 5.528934368163945e-05 0.0038819208044353 7021.101257392003 0.0003018833702723 0.0122981903697436 4073.8217407104894 0.0009190621795276 0.0264636528068129 2879.419194511198 0.0007624313517475 0.0233047560242428 3056.636636311821 +r_3800 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane 0.0001034988825511 0.0027636369537622 2670.209460856712 0.0001982204913362 0.0050728759306795 2559.2086350323075 0.00015973591359 0.0042577023275019 2665.463408829273 0.000269114027801 0.0067231353820764 2498.2478382905765 0.0007352949013251 0.0156551521720593 2129.098426202321 0.0001646453473126 0.00671988401289 4081.4296441245774 0.0009913428089221 0.0221709104348888 2236.4524395950434 0.0012250975203021 0.0305791914550623 2496.06181943134 0.0015904814710301 0.0339139015392883 2132.3040951443554 +r_3801 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane 9.429069101488323e-05 0.0025882991170511 2745.0208384225148 0.000134715313306 0.0042490815596027 3154.1191979774185 0.0001600210884092 0.0042556506929815 2659.431163284083 0.0001458079489639 0.0048013835391512 3292.9504689329124 0.0002805991629539 0.0095163376169043 3391.4347843102355 0.0002746963410276 0.0086720954405606 3156.9752287625465 0.0005276567440113 0.0160163742231574 3035.377526192034 0.0008237389163052 0.0245145524312798 2976.0099888488685 0.0016159897479212 0.0343936407112625 2128.332853318276 +r_3802 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane 7.494925781477871e-05 0.0023335534199787 3113.511044693252 0.0002151101761335 0.0053739835317257 2498.2470045444265 0.0002215137191642 0.0048654843357346 2196.470879588243 0.000201589528498 0.0058044972738886 2879.3644774776026 0.0008074401233511 0.0162242843012698 2009.3482887540208 0.0004519973192524 0.0109950888472223 2432.556207502838 0.00080782997212 0.020150822156869 2494.43853933589 0.0013524009528531 0.0310517096874707 2296.0431684080168 0.000589357904808 0.0207853024075439 3526.770785285794 +r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane 0.0001251671853875 0.0029730542646444 2375.266532868017 0.0001043001378471 0.0034114175929169 3270.769975316224 0.0001813603030309 0.0045260554850483 2495.615307984374 0.0001798942314637 0.005369123553671 2984.600178662576 0.0004684878267641 0.0125058010920634 2669.39723459626 0.000438682047909 0.0109460687072611 2495.216925204601 0.0005042115557964 0.0159184709868755 3157.1015784697115 0.0012232623605508 0.0305217078327856 2495.107249032141 0.001615561122114 0.0343713439001708 2127.517395020928 +r_3804 phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane 8.858663282303296e-05 0.0025559833654995 2885.292378823755 0.0002475258689424 0.0057058583264988 2305.156366434749 0.0003071355676349 0.005794472980335 1886.617373870252 0.0003479944322925 0.0075156890031062 2159.7153016485217 0.0002014164128152 0.0082009553513109 4071.642045790914 0.0002604790278438 0.008274425017709 3176.6185117478167 0.0011245056638338 0.0236135952775108 2099.908967732822 0.0008215056743211 0.0244872285898744 2980.774126741066 0.0008967306781125 0.0254340572300352 2836.309479627492 +r_3805 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane 3.806401514494498e-05 0.0038023169092862 9989.269116269788 0.0001384695469059 0.0059878262188796 4324.291046423934 0.0002171670252148 0.0048200692332107 2219.521692320505 0.0001592976885563 0.0074354081114059 4667.618330681567 0.0004959931017716 0.0135669412575652 2735.308456731497 0.0003445755570623 0.0141304808042913 4100.836671283445 0.0007270194379818 0.0234772488612911 3229.2463770241648 0.0009576144194264 0.0371923497795897 3883.854401635362 0.00023818852058 0.0281870223231031 11833.913009100255 +r_3806 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane 8.5277897661091e-05 0.0039467330354047 4628.084349698397 0.0002606490517621 0.0065160373663248 2499.9275164338856 0.0002257273608764 0.0048329112251841 2141.0391750554577 0.0002233265091559 0.009425022211188 4220.288154240874 0.0007549567435357 0.0166245979648186 2202.059668605451 0.0004949624615281 0.0113571275992718 2294.543219339699 0.001042714977471 0.0245256951913533 2352.099636166794 0.0006931472848687 0.0312726216141113 4511.684932882979 0.0020216833263278 0.033435791104925 1653.8589733367005 +r_3807 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane 6.388570578027411e-05 0.0032696509805553 5117.96956865574 0.00012488352704 0.006322583333538 5062.784086415284 1.109901345844087e-05 0.0059586523035241 53686.32379657652 0.0001337255508278 0.008375458240139 6263.169744517123 0.0001414135725649 0.0188486899248643 13328.770062861708 0.000129823480774 0.0116144864153409 8946.368057681824 0.0006529348943344 0.0200328570163819 3068.124738041949 0.0009939684150075 0.0350460043616685 3525.8670026655345 0.0006521930318464 0.0405091473264323 6211.220505031477 +r_3808 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane 4.60030925772528e-05 0.0034174826289912 7428.810624529812 0.0001012953474993 0.0054335831500157 5364.099422287392 2.4391829858437096e-05 0.0047536321646666 19488.624642986288 0.0001448041183867 0.0062908054817218 4344.355362131947 0.0006274144491971 0.0151335895746591 2412.056272217566 0.0005227543020085 0.0124352140580514 2378.7875126560425 1.7389946558308476e-05 0.0263747890439529 151666.8780753198 0.0012099889144988 0.0312762911714483 2584.8411333919003 0.0003466457456556 0.0376990585870681 10875.384757935622 +r_3809 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane 0.0001039863920412 0.0031993970256651 3076.7458730514354 4.663597360627062e-05 0.0064514906125672 13833.721296428015 2.648130497815669e-05 0.0057202699227772 21601.16326402968 0.0001422209028099 0.0084282724326853 5926.184032135922 0.0005291673756365 0.0147737012503873 2791.876810738169 0.0003386058971644 0.0125077052551511 3693.882876787764 0.0003487469861935 0.0262147599736539 7516.842011964643 0.0011386104588318 0.0378430452332064 3323.6165134151734 0.0015258532084973 0.0315539095265437 2067.9518416858773 +r_3810 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane 3.0160996899254182e-05 0.003623129055802 12012.630311604864 7.671319992829737e-05 0.0061651709877483 8036.649486021801 0.0001473266522145 0.0044393642376634 3013.2797908127127 5.206846572729524e-05 0.0070205671143592 13483.337786692164 0.0004439023617291 0.0154791263730492 3487.0565483712526 0.0002268038447185 0.0136494377265972 6018.16858243145 0.000322610861613 0.0218263205574685 6765.525639259638 0.0008016285911908 0.0345255604516633 4306.927276679828 0.0011404864640848 0.0323597811214818 2837.3665221399738 +r_3811 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane -8.963650087080593e-06 0.0034003993493069 -37935.43161851012 0.0002246044907186 0.0059866052329465 2665.398725462312 0.0001674406236673 0.0045970785824293 2745.497766158608 0.0001953487963005 0.0067901108052371 3475.8907829607087 0.000302136025512 0.0137467488324756 4549.854261562794 0.0005744229716797 0.0108828829894086 1894.5765622125843 0.0007030012913466 0.0201239165568723 2862.5717768345494 0.0009377840306882 0.0325520724246985 3471.169412088168 0.0006343375115206 0.0325159533545727 5125.970443813511 +r_3812 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane 5.980686686238705e-05 0.0036826899133084 6157.6372522274805 0.0002100139884887 0.0054873279712773 2612.8392735954376 0.0001798322217403 0.0046458358275151 2583.427921066421 0.0001743907791766 0.0080232997041617 4600.7591353399785 -0.0001502663428838 0.0150081123808647 -9987.673948030704 0.0001308780973953 0.0116624393161736 8910.91752422646 0.0009374359866989 0.0212149637721909 2263.0839943424708 0.0005873757710599 0.035747477721066 6085.963957375887 -2.2069109351475583e-05 0.0343213420629141 -155517.5676385841 +r_3813 phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane 0.0001127763909393 0.0002487382879747 220.55882964774875 0.0002398095825719 0.0003714050758253 154.8749936687801 0.0001652903824945 0.000580935576393 351.4636288123235 0.0004196789415789 0.000941324655988 224.2963758073128 0.0005729444618194 0.0012299820408682 214.6773592962828 0.0006600737101913 0.00165939571134 251.3955162460464 0.0008249095881982 0.002263301753716 274.3696747009112 0.000802939654602 0.0022461069129036 279.7354570832426 0.0011273964135471 0.0029321255391149 260.0793743781309 +r_3814 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane 3.9181405621685074e-05 0.0001855027863532 473.4459711435673 5.880840311086909e-05 0.0002194973513057 373.2414751883677 0.0001415996416323 0.0005862450183105 414.0158912495764 0.0001748169745197 0.000681408516555 389.78395457696274 0.0002701777718058 0.0010926550371035 404.4207744405627 0.0002570562834735 0.0011379099820112 442.6695845108436 0.0003265404311232 0.0015688795681625 480.4549203190454 0.0006923456011901 0.002779201501465 401.418236309692 0.0004190218261051 0.002149421620164 512.9617328393327 +r_3815 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane 4.732062840290904e-05 0.0002115117374116 446.9757578254128 8.749460407553554e-05 0.0002826026626396 322.99438991195245 0.0001579550399013 0.000406235012296 257.1839509203379 0.0001918117295759 0.0005494964275379 286.47696819833766 0.0003238279274472 0.0010202916167941 315.0721510764127 0.0006201636016057 0.0012795203046615 206.3198003476271 0.0003720723311737 0.0017686990271722 475.3642985472095 0.000524351514185 0.0022052901213161 420.57475980471895 0.0005116474814829 0.0018914007788863 369.6687362564945 +r_3816 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane 1.2629212213548674e-05 0.0002349371105065 1860.2673431563228 8.684691898024197e-06 0.0002317504640266 2668.493790544474 1.666717762390746e-05 0.0003537849877756 2122.6448518087445 3.3404351417821784e-05 0.000578046454991 1730.4525621850669 7.425456289313018e-05 0.0013131963712962 1768.505961291844 3.2070568606620294e-05 0.0007561683554796 2357.826469355336 4.602087527005137e-05 0.0011007964525585 2391.9502749547623 8.977165431411688e-05 0.002156179605979 2401.8490273493567 7.072015264239406e-05 0.0017543092235855 2480.635516238833 +r_3817 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane 0.0001037472268174 0.000250535666209 241.48661501083603 0.0002119286466104 0.0003892423686202 183.6667080386906 0.0003302400346522 0.0006887389638361 208.55707714581973 0.0005839000923703 0.0011603878838625 198.73055322733308 0.0007671874939541 0.0015869404535857 206.85171044779923 0.0020489700376793 0.0021581874635205 105.3303573909234 0.0009271781363251 0.002022172331995 218.09965666467625 0.0009369052621064 0.0024571046119262 262.25753139669933 0.0011651465891871 0.0034096946420488 292.6408293764703 +r_3818 phosphatidyl-L-serine (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane 1.957348682929145e-05 0.0001989120491288 1016.2320636258976 1.782706199103051e-05 0.0002157990064057 1210.5135805008351 4.656636350814144e-05 0.000504468777582 1083.3329888297524 5.150117421455275e-05 0.0004698121976246 912.23589518056 7.76254519760802e-05 0.0008526611058132 1098.429811495337 9.277763442306083e-05 0.0010163686060852 1095.4888130157683 0.0001224782291452 0.0016648747680418 1359.3230239042389 0.0001024244399729 0.0015256833275593 1489.5696065917286 0.0001654782866496 0.0024475559262069 1479.0798090562662 +r_3819 phosphatidyl-L-serine (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane 1.26490235674255e-05 0.000153808519102 1215.971480187482 2.3307567518694683e-05 0.0002007484334584 861.301520621878 3.027987860208172e-05 0.000286255672829 945.365985745347 6.283235110945872e-05 0.0006025796206065 959.027650512103 8.691560866043742e-05 0.0009918821101223 1141.2013623438752 0.0001079451969456 0.0009870568499562 914.4055297364702 0.0001158930849928 0.0012414666566453 1071.2171970585282 0.0001410820775858 0.001970458904399 1396.6755651157562 0.0001103045956026 0.0004457816200176 404.13694242021785 +r_3820 phosphatidyl-L-serine (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane 5.1894474476236505e-06 0.0001387787333136 2674.248746409841 1.002633775925678e-05 0.0002411319914705 2404.9857212116444 1.383011061628201e-05 0.0002953984653963 2135.908190412958 3.2021762091163745e-05 0.0005939732436071 1854.904929704069 5.399964564735802e-05 0.0010706160669265 1982.6353563839875 3.4906094495313254e-05 0.0008027276451298 2299.677625744108 4.627762943590104e-05 0.0010265515578066 2218.245770839572 9.016245597308452e-05 0.0020097181193182 2228.9966456971783 7.706722145325042e-05 0.0019918079002805 2584.507216844143 +r_3821 phosphatidylethanolamine (1-16:0, 2-16:1) transport, Golgi membrane-ER membrane 0.0001127763909393 0.0002487382879747 220.55882964774875 0.0002398095825719 0.0003714050758253 154.87499366878012 0.0001652903824945 0.000580935576393 351.4636288123235 0.0004196789415789 0.000941324655988 224.2963758073128 0.0005729444618194 0.0012299820408682 214.6773592962828 0.0006600737101913 0.00165939571134 251.3955162460464 0.0008249095881982 0.002263301753716 274.3696747009112 0.000802939654602 0.0022461069129036 279.7354570832426 0.0011273964135471 0.0029321255391149 260.0793743781309 +r_3822 phosphatidylethanolamine (1-16:1, 2-16:1) transport, Golgi membrane-ER membrane 3.9181405621685074e-05 0.0001855027863532 473.4459711435673 5.880840311086909e-05 0.0002194973513057 373.2414751883677 0.0001415996416323 0.0005862450183105 414.0158912495764 0.0001748169745197 0.000681408516555 389.78395457696286 0.0002701777718058 0.0010926550371035 404.4207744405627 0.0002570562834735 0.0011379099820112 442.6695845108436 0.0003265404311232 0.0015688795681625 480.4549203190454 0.0006923456011901 0.002779201501465 401.4182363096919 0.0004190218261051 0.002149421620164 512.9617328393327 +r_3823 phosphatidylethanolamine (1-18:0, 2-16:1) transport, Golgi membrane-ER membrane 4.732062840290904e-05 0.0002115117374116 446.9757578254128 8.749460407553554e-05 0.0002826026626396 322.99438991195245 0.0001579550399013 0.000406235012296 257.1839509203379 0.0001918117295759 0.0005494964275379 286.47696819833754 0.0003238279274472 0.0010202916167941 315.07215107641275 0.0006201636016057 0.0012795203046615 206.31980034762708 0.0003720723311737 0.0017686990271722 475.3642985472095 0.000524351514185 0.0022052901213161 420.5747598047189 0.0005116474814829 0.0018914007788863 369.6687362564945 +r_3824 phosphatidylethanolamine (1-18:1, 2-16:1) transport, Golgi membrane-ER membrane 1.2629212213548674e-05 0.0002349371105065 1860.2673431563228 8.684691898024197e-06 0.0002317504640266 2668.493790544474 1.666717762390746e-05 0.0003537849877756 2122.6448518087445 3.3404351417821784e-05 0.000578046454991 1730.4525621850669 7.425456289312066e-05 0.0013131963712962 1768.505961292071 3.2070568606620294e-05 0.0007561683554796 2357.826469355336 4.602087527005137e-05 0.0011007964525585 2391.9502749547623 8.977165431411688e-05 0.002156179605979 2401.8490273493567 7.072015264239406e-05 0.0017543092235855 2480.635516238833 +r_3825 phosphatidylethanolamine (1-16:0, 2-18:1) transport, Golgi membrane-ER membrane 0.0001037472268174 0.000250535666209 241.48661501083603 0.0002119286466104 0.0003892423686202 183.6667080386906 0.0003302400346522 0.0006887389638361 208.55707714581973 0.0005839000923703 0.0011603878838625 198.73055322733308 0.0007671874939541 0.0015869404535857 206.85171044779923 0.0020489700376793 0.0021581874635205 105.3303573909234 0.0009271781363251 0.002022172331995 218.09965666467625 0.0009369052621064 0.0024571046119262 262.25753139669933 0.0011651465891871 0.0034096946420488 292.6408293764703 +r_3826 phosphatidylethanolamine (1-16:1, 2-18:1) transport, Golgi membrane-ER membrane 1.957348682929145e-05 0.0001989120491288 1016.232063625898 1.7827061991030518e-05 0.0002157990064057 1210.513580500835 4.656636350814144e-05 0.000504468777582 1083.3329888297524 5.150117421455275e-05 0.0004698121976246 912.23589518056 7.76254519760802e-05 0.0008526611058132 1098.429811495337 9.277763442306083e-05 0.0010163686060852 1095.4888130157683 0.0001224782291452 0.0016648747680418 1359.3230239042389 0.0001024244399729 0.0015256833275593 1489.5696065917286 0.0001654782866496 0.0024475559262069 1479.0798090562662 +r_3827 phosphatidylethanolamine (1-18:0, 2-18:1) transport, Golgi membrane-ER membrane 1.26490235674255e-05 0.000153808519102 1215.9714801874825 2.3307567518694683e-05 0.0002007484334584 861.301520621878 3.027987860208172e-05 0.000286255672829 945.365985745347 6.283235110945872e-05 0.0006025796206065 959.0276505121032 8.691560866043742e-05 0.0009918821101223 1141.2013623438752 0.0001079451969456 0.0009870568499562 914.4055297364704 0.0001158930849928 0.0012414666566453 1071.2171970585282 0.0001410820775858 0.001970458904399 1396.6755651157562 0.0001103045956026 0.0004457816200176 404.136942420218 +r_3828 phosphatidylethanolamine (1-18:1, 2-18:1) transport, Golgi membrane-ER membrane 5.1894474476236505e-06 0.0001387787333136 2674.248746409841 1.0026337759256778e-05 0.0002411319914705 2404.9857212116444 1.383011061628201e-05 0.0002953984653963 2135.908190412958 3.2021762091163745e-05 0.0005939732436071 1854.904929704069 5.399964564735802e-05 0.0010706160669265 1982.6353563839875 3.4906094495313254e-05 0.0008027276451298 2299.677625744108 4.627762943590105e-05 0.0010265515578066 2218.245770839572 9.016245597308456e-05 0.0020097181193182 2228.996645697177 7.706722145325043e-05 0.0019918079002805 2584.5072168441425 +r_3829 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3830 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3831 phosphatidate (1-18:0, 2-16:1) transport, ER membrane-vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3832 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3833 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3834 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3835 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3836 phosphatidate (1-18:1, 2-18:1) transport, ER membrane-vacuolar membrane 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_3837 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) transport, ER membrane-vacuolar membrane 0.0002850253282445 0.0040295221193837 1413.741769617846 0.000647140957363 0.0083337911371574 1287.7860754039432 0.0004086289127551 0.0064088784370816 1568.3859455440884 0.0005192638031759 0.0087681285919486 1688.5691893638214 0.0012865857374954 0.0194924427125709 1515.0519817292966 0.0009574918986494 0.0145714460192299 1521.834914716643 0.0019110303583478 0.0283825578846977 1485.19659882513 0.0028030267608231 0.0404901232768787 1444.5143315359471 0.0030429976834572 0.0442859641126386 1455.34005344112 +r_3838 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) transport, ER membrane-vacuolar membrane 0.0003317842926749 0.0047360301697606 1427.442550573158 0.0004707566058567 0.0075271479817727 1598.946863012781 0.0003407688889712 0.0055437813286817 1626.8449110531094 0.000837432767717 0.0110551389522888 1320.1225672630294 0.0011062270759963 0.0178375593728866 1612.468159561226 0.0008202576317173 0.0136177053574094 1660.174173436062 0.0029688598160298 0.0351715288434116 1184.6813599452755 0.002101669901045 0.0370510822756982 1762.935380921328 0.0024156783465269 0.0389652223596821 1613.0136868471486 +r_3839 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, ER membrane-vacuolar membrane 0.0002745438809983 0.0040576708542993 1477.968053610862 0.000695860470016 0.0089488846915196 1286.0171079000056 0.0004306594280809 0.0064964288107494 1508.484056577502 0.0007791604454912 0.0103227436136442 1324.8546783116244 0.0015088085377685 0.0201055964466113 1332.547897452012 0.0009565956823692 0.0155521742329638 1625.783444312044 0.0014571889356302 0.0253530515391519 1739.860282989749 0.0024415050300358 0.0417191888451935 1708.7488386039126 0.0028573456734079 0.0435567337158251 1524.377471063022 +r_3840 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, ER membrane-vacuolar membrane 0.0003687043371244 0.004694508542417 1273.2447301895563 0.0004563760717055 0.0069583701857516 1524.700924776313 0.000379730803725 0.0061601118666238 1622.2312770509209 0.0006509657058861 0.0096359412982631 1480.2532930894474 0.0012377776631223 0.0190321410218274 1537.6057905115572 0.0010977619771159 0.0168164677437939 1531.8865195143649 0.002085689409642 0.0299271176822354 1434.8789203169056 0.0033197410842441 0.047337261501181 1425.932333272877 0.0039357277569539 0.048344347283027 1228.3458173042736 +r_3841 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, ER membrane-vacuolar membrane 0.0002430142702053 0.0038551887383118 1586.4042613855102 0.0005238294465723 0.0078450033166436 1497.6254901242648 0.0004477989558638 0.0067543358214601 1508.341127868576 0.000828685969822 0.0109087884722409 1316.3959412253455 0.001137721289581 0.0179141594643827 1574.5648454007644 0.0009575685484367 0.0150805871161294 1574.8832959007505 0.0019624560537986 0.0290598391989606 1480.7892967952694 0.0027445774021951 0.0423651746217866 1543.5955490962706 0.0026407538295888 0.0400967414692178 1518.3824035374537 +r_3842 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, ER membrane-vacuolar membrane 0.0002503633210923 0.0040304741667922 1609.8500967343682 0.0004966588535564 0.0077535862445619 1561.1493058143128 0.0004031349053629 0.006363400072866 1578.4790620243537 0.0005280075179386 0.0087977235134023 1666.2117895119138 0.0014227955587544 0.0206269889295448 1449.7507250867386 0.0016147217692149 0.0188827906617608 1169.4145097790488 0.0020621951431641 0.0307376401163578 1490.5301381514696 0.0037425351524956 0.0472520179436708 1262.5671107501057 0.002788287405443 0.0433262328020133 1553.8653840861548 +r_3843 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) transport, ER membrane-vacuolar membrane 0.0002657023338002 0.0041669500241059 1568.277539947522 0.0004767528726466 0.0074180652927004 1555.9560766817783 0.0003744877499273 0.0058296266444919 1556.6935488872564 0.0003809271672136 0.0069791378323649 1832.14494345858 0.0013342961441226 0.0193991147419196 1453.8837444272708 0.0010214474571057 0.0145600805085551 1425.4360718476105 0.0012576140836855 0.0243593402028571 1936.948744361296 0.0029395792014637 0.0438555709049929 1491.8996189371503 0.0023481985500269 0.0373463078301598 1590.423766752229 +r_3844 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, ER membrane-vacuolar membrane 0.0002478997399984 0.0041461901995945 1672.5270464669095 0.00062459932543 0.008487098011999 1358.8067848384153 0.0004459445375543 0.0060070556407848 1347.0409736888807 0.0005612594502063 0.0092584487199307 1649.5844687384106 0.0015066219643805 0.0215174348317999 1428.1907034752994 0.0009153670555709 0.014599295951079 1594.911665459966 0.0016848691755353 0.0259042543718367 1537.463842770248 0.00305649290811 0.0457162988835837 1495.7109425080014 0.003880659440881 0.0497742072180636 1282.6223990107032 +r_3845 phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-vacuolar membrane 0.0001503931393929 0.0002499606252911 166.2048058176651 0.0001427812062892 0.0003712938919789 260.0439523019838 0.0008879588434059 0.0007398798154884 83.32366088618336 0.0011044004219331 0.0012088059501949 109.45359365936234 0.001549370293862 0.001899282524874 122.58415773158218 0.0017826055325794 0.0019026881383922 106.736353254724 0.0021842540149115 0.0025851186051028 118.3524712535562 0.0025450806841589 0.003207824836755 126.04020205415038 0.0025090863921522 0.0033176243302813 132.22439612513733 +r_3846 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-vacuolar membrane 6.728214924130097e-05 0.0002719904600599 404.25352508363017 9.608581435050465e-05 0.0003081024665617 320.6534373927997 0.0002422973862553 0.0005773246957086 238.27111989572663 0.0003843479396681 0.0007631269580422 198.55107294219664 0.0004968028276787 0.0012212831810475 245.82854867266573 0.0007524217978873 0.0014003405493744 186.1111085971099 0.0007295005262563 0.0020818197192241 285.3760407696706 0.0007100674012849 0.0029439986332687 414.6083354821351 0.0011457054613979 0.0032102987019359 280.2027929603142 +r_3847 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-vacuolar membrane 7.606605882136595e-05 0.0002160356568916 284.010582694914 0.0001243948230918 0.0003883076348869 312.1573914696586 0.000317632000656 0.0004024433685276 126.70114084742316 0.0004284563562452 0.000751225306332 175.33298208372926 0.0006562420205939 0.0011202756553629 170.71074698159288 0.0005856889536101 0.0012498518467433 213.3985691618823 0.0007899396909825 0.0018362206182757 232.4507350671229 0.001119375967723 0.0031976118664402 285.66022128780315 0.0011659957459364 0.0018992815131538 162.88923178089988 +r_3848 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-vacuolar membrane 9.800383158245757e-06 0.0002002271053581 2043.053849273888 1.5462483064199148e-05 0.0002977370702848 1925.5450049561964 2.0947498570313098e-05 0.0003344183295744 1596.4594934900174 4.203415965639207e-05 0.0006449829665735 1534.425742886253 4.350367932250252e-05 0.0008574213655388 1970.9168945978145 5.075117935477155e-05 0.0006524119630832 1285.5109405885253 6.776831318296791e-05 0.0012350375936047 1822.4411020388025 7.83892324194028e-05 0.0015828397813107 2019.2056133961144 0.0001820244524426 0.0027054271593791 1486.2987489172017 +r_3849 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-vacuolar membrane 0.0001925997084327 0.0003073822276101 159.59641378035667 0.0003125198262818 0.0004202714473417 134.47833129241775 0.0008866477325929 0.0009032916185523 101.87717008091911 0.0012341472728362 0.001415611149224 114.70358363072424 0.0017716340908523 0.0022345360906488 126.12853309758503 0.001153214600039 0.001977924659378 171.5140147645644 0.0024679092594987 0.0027191208835095 110.17912725290957 0.0030374172600583 0.0031991373332413 105.32426266583808 0.0037180740898817 0.0038716035997763 104.12927516190004 +r_3850 phosphatidyl-L-serine (1-16:1, 2-18:1) transport, ER membrane-vacuolar membrane 2.442327536171555e-05 0.000226687414607 928.1614003435404 2.85983633962679e-05 0.000234352647024 819.4617425366905 8.012232498475257e-05 0.0004825983557118 602.3269492038671 0.0001036770893608 0.0005949678146736 573.866240209548 0.0001972253621641 0.001229361537062 623.3283202385645 0.0001537587610342 0.0009418992075569 612.5824643887075 0.0001841435834228 0.0013272601232462 720.7745708949186 0.0002858847270083 0.0018286923850324 639.6607486412238 0.0002918397415695 0.0024972627333964 855.6965956610541 +r_3851 phosphatidyl-L-serine (1-18:0, 2-18:1) transport, ER membrane-vacuolar membrane 1.974162761996894e-05 0.0001126588022278 570.6662307512227 3.466133054515255e-05 0.000291212934614 840.166635365421 0.0001067184339842 0.00055951350583 524.2894642857791 0.0001320265399501 0.0006589558322649 499.1086129454532 0.000183443021804 0.001152800207413 628.4241265086712 0.0001985522835905 0.0008826881581387 444.5620781470887 0.0003138695593335 0.0021545186399635 686.4375903602389 0.0003607321607927 0.0028292350486496 784.303523820059 0.0002863339627178 0.0022335713526464 780.058129131934 +r_3852 phosphatidyl-L-serine (1-18:1, 2-18:1) transport, ER membrane-vacuolar membrane 1.5476370737659267e-05 0.000258964557688 1673.289959757156 1.7980243067933403e-05 0.0003175113060406 1765.8899539960037 3.247680560698852e-05 0.0004642467000488 1429.4715609250677 3.820901052352666e-05 0.0005954513192547 1558.4054941389804 7.74237777956319e-05 0.0012823655972132 1656.2942725401197 6.046070021522032e-05 0.0009423685022396 1558.6463585191088 8.366810115575754e-05 0.0015090541322795 1803.6194337317588 0.0001826344240173 0.0029966294129323 1640.7801700341854 0.0001503481432771 0.0024995958026233 1662.5385243474957 +r_3853 phosphatidylethanolamine (1-16:0, 2-16:1) transport, vacuolar membrane-ER membrane 0.0001503931393929 0.0002499606252911 166.20480581766583 0.0001427812062892 0.0003712938919789 260.0439523019838 0.0008879588434059 0.0007398798154884 83.32366088618336 0.0011044004219331 0.0012088059501949 109.45359365936234 0.001549370293862 0.001899282524874 122.58415773158218 0.0017826055325794 0.0019026881383922 106.736353254724 0.0021842540149115 0.0025851186051028 118.3524712535562 0.0025450806841589 0.003207824836755 126.04020205415038 0.0025090863921522 0.0033176243302813 132.22439612513733 +r_3854 phosphatidylethanolamine (1-16:1, 2-16:1) transport, vacuolar membrane-ER membrane 6.728214924130097e-05 0.0002719904600599 404.2535250836301 9.608581435050465e-05 0.0003081024665617 320.6534373927997 0.0002422973862553 0.0005773246957086 238.27111989572663 0.0003843479396681 0.0007631269580422 198.55107294219664 0.0004968028276787 0.0012212831810475 245.82854867266573 0.0007524217978873 0.0014003405493744 186.1111085971099 0.0007295005262563 0.0020818197192241 285.3760407696706 0.0007100674012849 0.0029439986332687 414.6083354821351 0.0011457054613979 0.0032102987019359 280.2027929603141 +r_3855 phosphatidylethanolamine (1-18:0, 2-16:1) transport, vacuolar membrane-ER membrane 7.606605882136595e-05 0.0002160356568916 284.010582694914 0.0001243948230918 0.0003883076348869 312.1573914696586 0.000317632000656 0.0004024433685276 126.70114084742316 0.0004284563562452 0.000751225306332 175.33298208372926 0.0006562420205939 0.0011202756553629 170.71074698159288 0.0005856889536101 0.0012498518467433 213.3985691618823 0.0007899396909825 0.0018362206182757 232.4507350671229 0.001119375967723 0.0031976118664402 285.66022128780315 0.0011659957459364 0.0018992815131538 162.88923178089988 +r_3856 phosphatidylethanolamine (1-18:1, 2-16:1) transport, vacuolar membrane-ER membrane 9.800383158245757e-06 0.0002002271053581 2043.053849273888 1.5462483064199148e-05 0.0002977370702848 1925.5450049561964 2.0947498570313098e-05 0.0003344183295744 1596.4594934900174 4.203415965639207e-05 0.0006449829665735 1534.425742886253 4.350367932250252e-05 0.0008574213655388 1970.9168945978145 5.075117935477155e-05 0.0006524119630832 1285.5109405885253 6.776831318296791e-05 0.0012350375936047 1822.4411020388025 7.83892324194028e-05 0.0015828397813107 2019.2056133961144 0.0001820244524426 0.0027054271593791 1486.2987489172017 +r_3857 phosphatidylethanolamine (1-16:0, 2-18:1) transport, vacuolar membrane-ER membrane 0.0001925997084327 0.0003073822276101 159.59641378035667 0.0003125198262818 0.0004202714473417 134.47833129241775 0.0008866477325929 0.0009032916185523 101.87717008091911 0.0012341472728362 0.001415611149224 114.70358363072424 0.0017716340908523 0.0022345360906488 126.12853309758503 0.001153214600039 0.001977924659378 171.5140147645644 0.0024679092594987 0.0027191208835095 110.17912725290957 0.0030374172600583 0.0031991373332413 105.32426266583808 0.0037180740898817 0.0038716035997763 104.12927516190004 +r_3858 phosphatidylethanolamine (1-16:1, 2-18:1) transport, vacuolar membrane-ER membrane 2.442327536171555e-05 0.000226687414607 928.1614003435404 2.85983633962679e-05 0.000234352647024 819.4617425366905 8.012232498475257e-05 0.0004825983557118 602.3269492038671 0.0001036770893608 0.0005949678146736 573.866240209548 0.0001972253621641 0.001229361537062 623.3283202385645 0.0001537587610342 0.0009418992075569 612.5824643887075 0.0001841435834228 0.0013272601232462 720.7745708949186 0.0002858847270083 0.0018286923850324 639.6607486412238 0.0002918397415695 0.0024972627333964 855.6965956610541 +r_3859 phosphatidylethanolamine (1-18:0, 2-18:1) transport, vacuolar membrane-ER membrane 1.974162761996894e-05 0.0001126588022278 570.6662307512227 3.466133054515319e-05 0.000291212934614 840.166635365407 0.0001067184339842 0.00055951350583 524.2894642857791 0.0001320265399501 0.0006589558322649 499.1086129454532 0.000183443021804 0.001152800207413 628.4241265086712 0.0001985522835905 0.0008826881581387 444.5620781470887 0.0003138695593335 0.0021545186399635 686.4375903602389 0.0003607321607927 0.0028292350486496 784.3035238200406 0.0002863339627178 0.0022335713526464 780.0581291319209 +r_3860 phosphatidylethanolamine (1-18:1, 2-18:1) transport, vacuolar membrane-ER membrane 1.5476370737659267e-05 0.000258964557688 1673.289959757156 1.7980243067933403e-05 0.0003175113060406 1765.8899539960037 3.247680560698852e-05 0.0004642467000488 1429.4715609250677 3.820901052352666e-05 0.0005954513192547 1558.4054941389804 7.74237777956319e-05 0.0012823655972132 1656.2942725401192 6.046070021522032e-05 0.0009423685022396 1558.6463585191088 8.366810115575754e-05 0.0015090541322795 1803.6194337317588 0.0001826344240173 0.0029966294129323 1640.7801700341854 0.0001503481432771 0.0024995958026233 1662.5385243474957 +r_3861 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) transport, vacuolar membrane-ER membrane 3.563981592032252e-05 0.0015019039295826 4214.11808899443 0.000241872853617 0.0056964284916983 2355.133454007292 0.0002270209704547 0.0050717662925915 2234.0518950443206 0.0002012727780991 0.0058073415164291 2885.3089678959795 0.0007361930975097 0.0156800243848004 2129.879299037248 0.0001641623866406 0.0067005642779062 4081.668410788681 0.0007046859432498 0.0188222151318666 2671.0076044744533 0.0004582480150979 0.0187041594605975 4081.667316463461 0.0016142000470112 0.0343804275694785 2129.874028509388 +r_3862 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-16:1) transport, vacuolar membrane-ER membrane 0.0001476355179744 0.0032982592090348 2234.055364377822 0.0002150112419398 0.0053715056553707 2498.2440950099 0.0001135405899988 0.0035890337858576 3161.013859354722 0.0003023560233023 0.0071104111631742 2351.6684356122605 0.0004018428862428 0.0115944048016763 2885.307964533561 0.0003283248376815 0.0094731791874616 2885.3068973871923 0.0014079259328569 0.026572787089267 1887.371094539495 0.0007639559815246 0.0241487418213793 3161.012205596424 0.0011737017139392 0.029322014976068 2498.251014532077 +r_3863 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-16:1) transport, vacuolar membrane-ER membrane 8.858629430272985e-05 0.0025559832558957 2885.3032808450703 0.0003225161316044 0.0065760873933799 2038.9948746644827 9.083247500212928e-05 0.0032104525750756 3534.4766010178305 0.0002348184527229 0.006272016944103 2671.0068443823448 0.0002009217521376 0.0082009409569695 4081.659088535074 0.0004920513338927 0.0115885167840082 2355.143861175476 0.0007045850067966 0.0188195265472893 2671.008659813788 0.0012221594856474 0.0305325891500961 2498.249165404169 0.0008806653888956 0.0254099064607899 2885.3077208649006 +r_3864 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-16:1) transport, vacuolar membrane-ER membrane 0.0001327590350411 0.0031266627308222 2355.1411998832973 0.000134216342303 0.0042425931468608 3161.0108531200685 0.0001589568165679 0.0042457532110397 2671.0104685718607 0.0003326178434938 0.0074319664568971 2234.385978464508 0.0006022423155153 0.0141836537700627 2355.140680861205 0.0007108516166692 0.0139242482791483 1958.812212370287 0.0005033470736147 0.0159108652372733 3161.0127626270046 0.0019862855825059 0.0389074842526128 1958.8061553327304 0.0011739218320733 0.0293275011901612 2498.2499165522104 +r_3865 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-18:1) transport, vacuolar membrane-ER membrane 8.857342105515794e-05 0.0025556061005813 2885.296819448702 0.0001880082735246 0.0050217252377576 2671.012899386866 0.0001589569590398 0.0042457533617579 2671.008169384209 0.0003352453952758 0.0074895794657216 2234.058862929174 0.0004685995833914 0.0125163431379087 2671.0102999499486 0.0003830367921897 0.0102309464619786 2671.008809229434 0.0005029770044549 0.0158991855414791 3161.016388554168 0.0009167471209616 0.0264509759825091 2885.307777652058 0.0011735866000503 0.0293191487309118 2498.2518315779143 +r_3866 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-18:1) transport, vacuolar membrane-ER membrane 7.382191186981116e-05 0.0023335162835541 3161.0076526728285 0.0002148111051515 0.0053665274499142 2498.254196927531 0.0002273137775347 0.005061893114742 2226.8307577473706 0.0002012728878119 0.005807343858618 2885.308558817588 0.0007366223691331 0.0156891237039152 2129.8733735684364 0.0006018436098984 0.012818511597953 2129.874171151379 0.0011067609870194 0.0235726351561169 2129.8758659355453 0.0012223134007382 0.0305364344753704 2498.24917708726 0.0016143464160986 0.0343835422280404 2129.873853911367 +r_3867 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-18:1) transport, vacuolar membrane-ER membrane 8.858610493297463e-05 0.0025559838303888 2885.310097246941 0.0002148349740624 0.0053671036712225 2498.24484800227 0.0001360521882083 0.0039255441895307 2885.322346685594 6.696544591470373e-05 0.0033479387771886 4999.501954266109 0.0005983132584983 0.01409314745398 2355.4797179911216 0.0003825254458793 0.0102173287044084 2671.0193568745576 0.0007043412521652 0.0188130204839128 2671.009319144596 0.0013749592565866 0.0323821621446074 2355.136124178414 0.0005871101445987 0.0207512521384338 3534.4734423924456 +r_3868 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-18:1) transport, vacuolar membrane-ER membrane 0.0001032823976885 0.002758685711381 2671.012460128208 0.000349242116154 0.006840985100203 1958.808741493679 0.0001127205594999 0.0035634922559145 3161.350752446051 0.0002348183238276 0.0062720181789883 2671.0088364276708 0.000736503595086 0.0156866043477247 2129.8747830135035 0.0003280633787591 0.0094656555639976 2885.3130757233894 0.0006034976101006 0.0174127973104945 2885.313383028956 0.0013771457646683 0.0323762579474099 2350.9681239303973 0.0017530473387678 0.0357477675637835 2039.1786789345065 +r_3869 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) transport, ER membrane-cell envelope 0.0002111971959913 0.0050061489286998 2370.3671373105044 0.0002989528856173 0.0070793820219855 2368.059437649259 0.0004019891287273 0.0068498928370107 1703.9995232450085 0.0004459976801838 0.0100566594390559 2254.8681048991043 0.00089311111473 0.0189445348374814 2121.18453404388 0.0006835281271528 0.0170359981389487 2492.362415268765 0.0011140703065114 0.026183858572626 2350.287806755945 0.0018081064659368 0.0477000578450962 2638.122187145719 0.0016654243308877 0.0421630116488456 2531.6678078295085 +r_3870 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) transport, ER membrane-cell envelope 0.000167238379516 0.0039050331544418 2335.010160790748 0.0004311318688387 0.0084381728974385 1957.2139077000425 0.0003474534116915 0.0074811439476599 2153.135843806489 0.0002524093239167 0.0087311795539026 3459.1351137185434 0.0005734856529934 0.0147098454804999 2564.989272829679 0.0005048474941863 0.0138279362061083 2739.032354393151 0.0009839187008475 0.0273080132908345 2775.433912101781 0.0018197955830679 0.038525166794607 2117.00518195881 0.0013951115895764 0.0353031107206033 2530.486520531353 +r_3871 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, ER membrane-cell envelope 0.0001928709586718 0.0043758621224402 2268.803013462656 0.0004471265223226 0.0091527544989348 2047.016681405816 0.0001844470507362 0.0055231838392043 2994.454949080631 0.000359442517762 0.0089063282795889 2477.8171305504 0.0002721855016918 0.0170100436258177 6249.430450956295 0.000625141041594 0.0142233514168476 2275.222785018128 0.0014173268019791 0.0291294209956713 2055.2367283956864 0.001476566931442 0.0367215318941831 2486.953426372693 0.0016206626999446 0.0371140913296939 2290.056489296724 +r_3872 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, ER membrane-cell envelope 0.0001625416140664 0.0039707924050189 2442.938953095094 0.0001089556468447 0.0064379103325983 5908.744079847687 0.0002123889854264 0.0054399046753177 2561.2932160274854 0.0003192397003737 0.0082956880143065 2598.5765569235823 0.0008346878651735 0.0186701841265159 2236.786337205672 0.0007776053838842 0.0157174346042718 2021.2610316251137 0.001266675389663 0.0310808787474901 2453.736687483773 0.0013759253999997 0.0389303841957612 2829.396433539753 0.0007526631433137 0.0408376873679116 5425.758884394586 +r_3873 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, ER membrane-cell envelope 0.0002390406473901 0.0043994479058563 1840.4601702217465 0.0002921051142277 0.0067962082445065 2326.631035706116 0.0002393002289536 0.0062001474559271 2590.949236879902 0.0005984283678719 0.0114973615128965 1921.259440588021 0.0007763083163887 0.0172020208156702 2215.874859577928 0.0002028897445166 0.0109921394628996 5417.7895926116935 0.0005841646708477 0.0264147238472192 4521.794138780327 0.0012891347341237 0.0382525967302703 2967.307894024761 0.001238620128263 0.0369530580700167 2983.4052609687155 +r_3874 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, ER membrane-cell envelope 0.0001602457964437 0.0042653839319606 2661.7758634674 0.000372651328752 0.0078627337775003 2109.9438458549685 0.0001579234083372 0.005231055064559 3312.4000549615184 0.0002756336308498 0.00838876048238 3043.44591642022 0.0006101125735145 0.0157017905892848 2573.589083541563 0.0003554122622343 0.014997213030601 4219.666743155958 0.0008003102282753 0.0216945662354144 2710.7695827109974 0.000644022301012 0.04041408928738 6275.2623975705055 0.0017211355113722 0.0355744604454442 2066.91804395352 +r_3875 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) transport, ER membrane-cell envelope 0.0001685358100456 0.0038379625366586 2277.238609183519 0.0001460208186944 0.0063098285541002 4321.184205453388 0.0002628697195127 0.0059153422289079 2250.2942673932525 0.000200706500172 0.0079408099632289 3956.428893146479 0.0003086422222851 0.0148598765376915 4814.596145554017 0.000137697481408 0.0125528364236013 9116.242574114369 0.0013688159034737 0.0261749432189673 1912.23254730908 0.0015461463320237 0.0406671627513594 2630.2272889093497 0.0013762095090763 0.037888674738119 2753.118219881316 +r_3876 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, ER membrane-cell envelope 9.015954644400852e-05 0.0033555363795973 3721.776020336656 0.0001629419385616 0.0065371450038449 4011.947483594661 0.0001572759311809 0.0064746446246497 4116.742196999844 0.0003185021129738 0.0081756588653483 2566.9088311569853 0.0006156255209936 0.0159482098416274 2590.5699646572857 0.000813105139729 0.0155270812082884 1909.603131209088 0.0008969644340556 0.0248139030907128 2766.431103462656 0.0016277626532756 0.0372987645963719 2291.412972358889 0.0008361503761392 0.0339862262151359 4064.606939730171 +r_3877 phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-cell envelope 5.963480767145262e-05 0.0010118319773835 1696.7137430174212 9.934691088018906e-05 0.001741148056502 1752.5940576067665 8.920516669359993e-05 0.0015899993663679 1782.4072587961232 0.0001455790544272 0.0022134018101477 1520.4122728066486 0.0002593707217118 0.0044851817845034 1729.2552354798115 0.0002284222869571 0.003641783946757 1594.3207623346736 0.0006002335294218 0.0091916464098143 1531.345044764044 0.0008457637993153 0.0136565513035023 1614.7003826076054 0.0008790773009802 0.013258077934978 1508.1811258457703 +r_3878 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope 7.535321942826299e-05 0.0011631853116834 1543.6438157640312 0.0001406243924156 0.0024224860547007 1722.6641929525706 0.000157346585238 0.0021288766225558 1352.985588683277 0.0002046897264939 0.0030664174644619 1498.080786459024 0.0003071766528824 0.0047530800566589 1547.3441786858798 0.0002728125807474 0.0043584519069127 1597.599309742709 0.0006483151650237 0.009225495595127 1422.995495530277 0.0007648323090322 0.0121407092893081 1587.3687795263872 0.0006674888650599 0.0107417974762155 1609.2848942508706 +r_3879 phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope 7.246694133764449e-05 0.001180907380117 1629.5808244684388 0.0001509481073043 0.0023736665609685 1572.505017358034 7.40932985452392e-05 0.0013834687324757 1867.1981942214168 0.0001431654971205 0.0021788905456636 1521.9383088017328 0.0004328405286591 0.006490814454345 1499.5856498123524 0.0003153786026187 0.0045549044808388 1444.2655408506585 0.000340928481862 0.0051317051621103 1505.2145640877438 0.0009567042876818 0.0135862912354713 1420.1139694263836 0.0008017147760094 0.013210542077578 1647.7857802913732 +r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope 8.575222105978711e-05 0.0013149249611062 1533.4004703964752 0.000113898515811 0.0020305185568411 1782.7436489241436 9.293132488911645e-05 0.0016407130947387 1765.511356581239 0.0001311954719722 0.0022537966421287 1717.892095091717 0.0003910984944195 0.0059897414412708 1531.517386728879 0.0003261292870596 0.005014805166313 1537.673973265706 0.000466959742147 0.0083567636418644 1789.6111565080928 0.0009891909986462 0.0148569327733247 1501.9276149558043 0.0008663579803309 0.0129752040878975 1497.6723689832872 +r_3881 phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope 7.441823338493e-05 0.001163725825188 1563.7643790449138 9.826245105853178e-05 0.001837344761257 1869.8340428762376 0.0001185025887787 0.0019322786804091 1630.5792981594122 0.0001613016289499 0.0024545935056057 1521.7413001868665 0.0003489830603306 0.0056273896981169 1612.5108458803704 0.0003477940948869 0.0051096682025113 1469.1647378810426 0.000405022510076 0.0068880909242468 1700.6686672680892 0.0005967014618426 0.0108645749565128 1820.772304287912 0.0009822994911812 0.0135423294329171 1378.635492993349 +r_3882 phosphatidylcholine (1-16:1, 2-18:1) transport, ER membrane-cell envelope 6.715430943337724e-05 0.00112718616612 1678.501611632752 0.0001167341886901 0.0021986465360408 1883.464099688336 0.0001167179042424 0.0017921018061135 1535.4129409239272 9.524364912656166e-05 0.0019805172215514 2079.4218194219484 0.0002760567616485 0.004944961829841 1791.284444659533 0.0002720033624331 0.004480036627412 1647.0519288205694 0.000486510248256 0.00837458677685 1721.3587600404412 0.0007130483043581 0.0125882488170456 1765.4131901171145 0.0005456755636929 0.0102068239978391 1870.4931422553527 +r_3883 phosphatidylcholine (1-18:0, 2-18:1) transport, ER membrane-cell envelope 6.240852708179033e-05 0.0010987783880479 1760.6222088976804 0.0001157680622274 0.0020364341296165 1759.063847519414 0.0001523645109142 0.0020973764087445 1376.5517942202666 0.0002007101042875 0.0029681607132925 1478.8297399521289 0.000214089442193 0.0037727719764011 1762.2410230759822 0.0003111567580409 0.0047073408293417 1512.8518689354214 0.0007646651413775 0.0099176006124916 1296.9861022596729 0.0007107364416683 0.0113581321269786 1598.079324639163 0.0008463904566496 0.012831067582903 1515.9749831883812 +r_3884 phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-cell envelope 6.53571941889197e-05 0.0011506153294737 1760.5029465429268 0.0001767936958949 0.0026588682709858 1503.9383941411002 0.0001279191377607 0.0019520143928987 1525.975258330211 0.0001825731383708 0.002838953166884 1554.9676103593677 0.0006189037611731 0.00760197554185 1228.2968724313291 0.0003438237818702 0.0050940293177999 1481.581433980507 0.0004749275982018 0.007540836006689 1587.7864405519983 0.001037225385503 0.014613842201658 1408.936033181528 0.0008067024764259 0.0127276719739338 1577.7405358072954 +r_3885 phosphatidylethanolamine (1-16:0, 2-16:1) transport, ER membrane-cell envelope 3.5162796011112227e-10 7.382594019216151e-10 209.95469236527973 2.9014550561169475e-10 1.258664281356949e-09 433.8045073982413 3.6539781461265545e-10 1.082032467908405e-09 296.12450448162286 3.14296674921637e-10 7.208562497750211e-10 229.3553534903768 3.4850000000002356e-10 7.390506600122014e-10 212.06618651711668 3.3059970950642363e-10 1.0741004214689676e-09 324.89454484777684 3.8830000000091175e-10 7.35544532704295e-10 189.42686909672105 2.501525730090978e-10 1.1061606927076244e-09 442.1944093564826 3.387121021950538e-10 6.810373478747734e-10 201.0667299636625 +r_3886 phosphatidylethanolamine (1-16:1, 2-16:1) transport, ER membrane-cell envelope 3.2221219535564473e-10 7.509198092901626e-10 233.05133080432543 2.6146646860987937e-10 1.451705790167057e-09 555.2168115036854 3.664278953193351e-10 9.73117968597596e-10 265.5687465468593 2.0680057920772855e-10 9.834069096350739e-10 475.533924229126 3.0675945397664956e-10 8.360043039902796e-10 272.5276411705688 3.346166666668341e-10 6.979772033377393e-10 208.5900891579589 3.2946805872063107e-10 7.608268732915013e-10 230.9258373166415 4.0314231018892337e-10 6.704863066376394e-10 166.3150430237479 3.014921473369184e-10 6.951907340962386e-10 230.58336352600287 +r_3887 phosphatidylethanolamine (1-18:0, 2-16:1) transport, ER membrane-cell envelope 2.9960000000000634e-10 8.217916858800816e-10 274.296290347151 2.483771614261318e-10 1.8700512593483744e-09 752.9078956418198 2.9096919185392004e-10 9.410976588039224e-10 323.4354994106719 2.809878560287416e-10 7.82446223165141e-10 278.4626475405778 3.3662222165679803e-10 8.225447751902102e-10 244.35248841914924 2.0185653403573727e-10 1.1016419968514786e-09 545.7549353623801 3.690343110955329e-10 7.760560745287014e-10 210.29374537691743 3.9991972449240006e-10 1.0293478218111367e-09 257.3886104561712 3.1953092002761056e-10 1.5732071373256e-09 492.3489523923567 +r_3888 phosphatidylethanolamine (1-18:1, 2-16:1) transport, ER membrane-cell envelope 2.236533307635482e-10 2.0116731624966432e-09 899.4604084941768 3.3409065468770505e-10 7.014970571917371e-10 209.97206816439365 3.5680309844972845e-10 1.580040192627226e-09 442.8325313015308 3.8790000000001285e-10 6.400511878784509e-10 165.00417320918527 3.351439653744035e-10 1.2030576909624383e-09 358.9674334784611 3.507886443988448e-10 6.83219807920035e-10 194.76679728070613 4.049000000028428e-10 7.586969844080267e-10 187.37885512538904 3.99498214423485e-10 1.074247427566951e-09 268.89918121841805 3.148075838936103e-10 1.3831365720265864e-09 439.3593556164199 +r_3889 phosphatidylethanolamine (1-16:0, 2-18:1) transport, ER membrane-cell envelope -3.967047840222416e-10 1.7795534201447943e-09 -448.58380635133005 -5.556857072221853e-10 1.5939906913189442e-09 -286.8511229642988 -4.316663079542811e-10 1.6154564927327355e-09 -374.2373363324507 -3.989082501792825e-10 1.2034387277613542e-09 -301.6830880836608 -5.596011138080919e-10 1.2872010535330034e-09 -230.0211743278325 -3.4382498926566747e-10 1.1438235473230388e-09 -332.6760948254481 -5.421088686039206e-10 1.369654645497906e-09 -252.65306008092864 -1.460142310188889e-09 1.6055484079933395e-09 -109.95835109973903 -3.2173333333333845e-10 1.0116505295928187e-09 -314.4375869020314 +r_3890 phosphatidylethanolamine (1-16:1, 2-18:1) transport, ER membrane-cell envelope -2.3522366705734354e-10 9.326959120461128e-10 -396.51448500662025 -1.302214703415526e-10 1.5386488096335302e-09 -1181.563075273126 -2.1799383528336567e-10 1.0643063104413843e-09 -488.2277102276376 -1.9287150872557902e-10 9.66255729163141e-10 -500.9841710410151 -1.7908527337209474e-10 9.795190262483519e-10 -546.9567697021935 -2.339000000000016e-10 8.972746571491392e-10 -383.6146460663247 -2.3107842558676926e-10 2.0431397111760707e-09 -884.1758835719943 2.729999999999989e-11 8.937921922329663e-10 3273.964074113443 -8.590000000000002e-11 8.028699209847313e-10 -934.6564854304208 +r_3891 phosphatidylethanolamine (1-18:0, 2-18:1) transport, ER membrane-cell envelope -4.4011666666667294e-10 1.2027049179021916e-09 -273.26956895569526 -3.4507602144233236e-10 2.341308399203573e-09 -678.4906089439318 -2.8320293515921475e-10 1.2896016738249582e-09 -455.3631031754501 -5.325442670727517e-10 1.2932704025573144e-09 -242.8474931607213 -4.22748838223621e-10 1.2341967219585292e-09 -291.9456212214775 -4.103714331131763e-10 1.4595007322983601e-09 -355.6535895362493 -4.2658221155982256e-10 1.982973612341254e-09 -464.8514538593619 -1.7521972449238664e-10 1.3197491275366315e-09 -753.1966685599799 -4.939508542954996e-10 1.694786775377697e-09 -343.108380244609 +r_3892 phosphatidylethanolamine (1-18:1, 2-18:1) transport, ER membrane-cell envelope -1.2504836848404835e-10 2.5843966478311714e-09 -2066.717606284361 -1.0309659132937752e-10 1.612692715622878e-09 -1564.254157026954 -4.4673492183874947e-10 1.852158161481652e-09 -414.5989200616367 -6.566108418050534e-11 1.155790014099422e-09 -1760.2359579109325 -1.6559041560411563e-10 1.5446576947708243e-09 -932.81829696213 -2.297651322288248e-10 1.3453757999748658e-09 -585.5439365077361 -2.919328640693697e-10 1.7468555884392751e-09 -598.3757923274386 1.5534921256743186e-10 1.521608569209828e-09 979.4762033630192 -3.7295856582424525e-10 1.903930329477286e-09 -510.4937931294232 +r_3893 phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-cell envelope 2.1977202102094967e-10 1.16184334651289e-09 528.6584439254611 1.7086848539560786e-10 1.1007063628818314e-09 644.1833673034508 3.758286797446024e-10 7.34078178353779e-10 195.32255464181927 2.814487974076753e-10 7.861523853000072e-10 279.3234124789224 1.4937207001371348e-10 1.019833249499273e-09 682.7469482117004 1.9108599606401856e-10 7.719545539924687e-10 403.9827982652612 2.432084481656006e-10 8.22631897865967e-10 338.2414978059632 2.077546953374057e-10 8.492929624755023e-10 408.7960376039644 1.3656537335308014e-10 8.61046928343163e-10 630.501647088085 +r_3894 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-cell envelope 2.517626818404487e-11 1.145684137821654e-09 4550.6511507043615 7.323061497432054e-11 1.122462783405386e-09 1532.7780379817857 1.8311875137517203e-10 1.3156092636860975e-09 718.4459558653768 1.5470221669877019e-10 9.248335306966221e-10 597.8153063555773 1.2751624309809602e-10 1.0287849206394944e-09 806.7873516694403 1.6572651092962008e-10 9.229100646491143e-10 556.8874041166843 2.331967515539223e-10 9.777939667436043e-10 419.2999946302889 2.2239130958084816e-10 8.132650391846475e-10 365.691015857341 2.353970349021797e-10 8.26825485311998e-10 351.2471963190145 +r_3895 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-cell envelope 2.923071568249998e-10 7.99844356466951e-10 273.6314653239253 1.417595696729724e-10 1.016177989523228e-09 716.8320218998033 2.692870484230709e-10 9.47446210918325e-10 351.8350460842861 1.7562211975936018e-10 8.338661158908055e-10 474.80699870459387 1.855759378934217e-10 1.1970277409331363e-09 645.0339168543513 2.0640725753222843e-10 8.288830526196797e-10 401.5765058504583 2.6094529263933907e-10 9.364559475695428e-10 358.8706039100114 2.529652295443013e-10 7.579163301768686e-10 299.61284858879634 1.699979569650405e-10 1.1075672936581707e-09 651.5180025874889 +r_3896 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-cell envelope 3.1480000000000847e-10 7.015692409733712e-10 222.8618935747625 2.8840225551636194e-10 1.0789854606097052e-09 374.1251810523691 3.9870000000001404e-10 6.522065506240566e-10 163.58328332682055 3.4819999999995745e-10 6.155749722894464e-10 176.78775769371674 2.0536864924430195e-10 7.263936049745011e-10 353.7022849628813 4.9800000000000005e-11 7.7455790486545e-10 1555.3371583643575 3.1003333333334096e-10 7.803460829099685e-10 251.6974786291633 1.4339999999999909e-10 6.818573354340129e-10 475.4932604142379 -1.3730000000000078e-10 1.2313821382471315e-09 -896.8551625980514 +r_3897 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-cell envelope -4.2487457690476944e-10 1.161412214482666e-09 -273.3541326345311 -7.121749628282513e-10 1.325458820129402e-09 -186.11421200004344 -5.016835058650749e-10 1.065584122000137e-09 -212.401665500783 -4.2476923507180184e-10 1.1149959007567635e-09 -262.49450494414634 -4.111247890777197e-10 1.061243472050636e-09 -258.1317157818029 -3.7519670642423184e-10 1.0174145411006892e-09 -271.16830283427566 -6.25422263689823e-10 1.3008470567557654e-09 -207.99500310096383 -5.415565489440815e-10 1.012428501771732e-09 -186.94788268108832 -2.0919867026003788e-10 1.016765627730994e-09 -486.0287240196772 +r_3898 phosphatidyl-L-serine (1-16:1, 2-18:1) transport, ER membrane-cell envelope -6.947115945729664e-11 8.651271569816713e-10 -1245.3040423392645 -1.7962425422724296e-10 1.1021463697357703e-09 -613.5843817291195 -6.350199996901285e-10 1.6388905650344964e-09 -258.0848738361356 -5.780099431332586e-10 1.1282997889513292e-09 -195.2042179127708 -2.9744951187466763e-10 1.206170773724483e-09 -405.50437152262367 -5.730217080900386e-10 9.46327488978263e-10 -165.14688285239737 -3.6479034513096334e-10 1.0403301232201587e-09 -285.1857613848497 -3.8320000000000975e-10 8.53348346620611e-10 -222.690069577398 -5.52993480922497e-10 1.761197027599137e-09 -318.4842296262026 +r_3899 phosphatidyl-L-serine (1-18:0, 2-18:1) transport, ER membrane-cell envelope -4.951077456686119e-10 1.1455945745587095e-09 -231.38288273225376 -3.555613667176817e-10 1.1499292980029287e-09 -323.4123292466644 -2.231756399250039e-10 1.3411976789376502e-09 -600.9606063584481 -2.82306362339735e-10 1.0800051999615514e-09 -382.56495213588 -3.27067798843417e-10 9.293055070826519e-10 -284.13237572420115 -3.5231009975420367e-10 9.66379578206197e-10 -274.2980058988974 -4.1245318367282756e-10 1.0660753297813751e-09 -258.47183922503643 -4.3334451333912165e-10 9.039216705497795e-10 -208.59192691391004 -2.4161639951499255e-10 1.709428004295537e-09 -707.4966797481248 +r_3900 phosphatidyl-L-serine (1-18:1, 2-18:1) transport, ER membrane-cell envelope -1.382019639993181e-10 1.387071829364266e-09 -1003.6556567105732 -2.551003417860747e-10 1.5412818105418995e-09 -604.1864937344566 -1.1345533406264568e-10 1.0743165570704152e-09 -946.907050202875 -9.528759332097235e-11 1.103581799279755e-09 -1158.1589594380716 -4.380075345084088e-10 1.342862904973527e-09 -306.5844304437979 -3.5940630562911287e-10 1.0942788548327216e-09 -304.4684630441503 -1.3445696355507674e-10 1.33954236694357e-09 -996.26105746086 -6.310285820613174e-10 1.0963845436684691e-09 -173.7456233895176 -6.487887690904669e-11 1.3403490828871524e-09 -2065.925223653579 +r_3901 lignoceric acid transport, cell envelope-ER membrane -6.332171725249531e-10 1.7799941953635152e-08 -2811.0327271539218 -5.153356762071352e-10 1.1790701802016513e-08 -2287.9653682811054 4.221671836781314e-10 5.159236458145348e-09 1222.083728345605 -8.468197355293266e-10 4.236101302708548e-09 -500.2364877645021 2.9097619745526905e-10 9.771622072348983e-09 3358.2204172735296 -6.938857321375879e-11 9.953492738085407e-10 -1434.4570405594916 1.2705543568462563e-10 5.954516111528158e-09 4686.549677660651 -4.124626698114077e-09 1.8954244802053692e-08 -459.5384307316886 -1.0998109897524772e-09 9.156410223732084e-09 -832.5439833796187 +r_3902 cerotic acid transport, cell envelope-ER membrane 6.332171726542677e-10 1.7799941962156532e-08 2811.0327279255857 5.153356762323507e-10 1.1790701802010906e-08 2287.965368168067 -4.2216718367523176e-10 5.159236458144875e-09 -1222.083728353887 8.468197355290631e-10 4.2361013027091165e-09 500.23648776472464 -2.9097623544372206e-10 9.77162207510148e-09 -3358.21997978643 6.938857321375879e-11 9.953492738085407e-10 1434.4570405594916 -1.270554356532105e-10 5.954516111539937e-09 -4686.549678828696 4.124626705728004e-09 1.89542447943037e-08 459.5384296955 1.0998109897574107e-09 9.156410223736525e-09 832.5439833762875 +r_3903 phosphatidate (1-16:0, 2-16:1) transport, cell envelope-ER membrane 4.958911392389635e-05 0.0009515026296174 1918.7732030818183 7.686773721012896e-05 0.0015917919631254 2070.819333180193 8.154223999854659e-05 0.0015459735106891 1895.9173928956773 0.0001117659933296 0.0019948606611561 1784.8547681871614 0.0002035593209292 0.0041263965959543 2027.1224020193688 0.0002003177054881 0.0034675593937336 1731.029908356373 0.0005820829140819 0.0091157805772615 1566.0622149747032 0.0007690408429377 0.0133002137637456 1729.4547989075372 0.00075490577609 0.0126890601287885 1680.8799893557484 +r_3904 phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane 5.8307785711446855e-05 0.0010722077477958 1838.875777416668 0.0001316658685767 0.0023812160366757 1808.5294711654583 0.0001425604066898 0.0020646372527892 1448.2543230124627 0.0001767354078645 0.002938020859024 1662.383839505234 0.0002182565793828 0.0042120136933304 1929.8450040961293 0.0002541867396589 0.0042630084976308 1677.1167934847829 0.0005495949329558 0.0087803751635653 1597.608463444648 0.0007391479903981 0.0120080090445137 1624.5744019469594 0.0005940966020744 0.010319907948368 1737.075740263985 +r_3905 phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane 6.75285038241981e-05 0.0011574738309962 1714.0522378662674 0.00014297927948 0.0023412074699477 1637.4452847022842 6.996940096345595e-05 0.0013574274496171 1940.0301144868968 0.0001158447431695 0.0020018611252044 1728.0552146202926 0.0003874000818709 0.0062986016047729 1625.8648099281888 0.0002963942409545 0.0044638609676987 1506.055230129439 0.0002915957183264 0.0047278528273405 1621.372513449359 0.0008283958219032 0.0129845921186431 1567.4381467558742 0.0007531248571685 0.0130013504721074 1726.3207220363945 +r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane 7.837003123648772e-05 0.001280388132199 1633.7726449736244 0.0001004170507216 0.0019557227773816 1947.600296291018 8.537064666309933e-05 0.0015969823264486 1870.645694826348 0.0001200136642006 0.0021839787262291 1819.7750570947924 0.0003792529897565 0.0059382012109557 1565.7625309078694 0.0002532911570299 0.0046769527007114 1846.4729505575424 0.0004325416217914 0.0082001800202563 1895.812936173193 0.0008405977080759 0.0142310681312933 1692.970132391425 0.0008419607696989 0.0128616068906962 1527.577929230029 +r_3907 phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane 5.985038156993698e-05 0.001086785162424 1815.8366478485225 8.93857079592135e-05 0.0017833825415273 1995.154015383672 0.0001035254938224 0.0018598747833222 1796.5379489157033 0.0001393855116657 0.0023304542805672 1671.9487217264273 0.0003159664552066 0.0054654856431885 1729.767686767294 0.0003060236769275 0.004935868723471 1612.9041952004318 0.0003393065033961 0.0064877724846873 1912.0684159454192 0.0004966802499726 0.0102778078679933 2069.3006956810227 0.000841955032064 0.0129317133331894 1535.9149646611486 +r_3908 phosphatidate (1-16:1, 2-18:1) transport, cell envelope-ER membrane 5.7317987539936185e-05 0.0010736428074712 1873.134165297021 0.0001077752875029 0.0021529906094248 1997.6663104389245 0.0001023184949685 0.0017213331660653 1682.3284652440368 7.84708838340727e-05 0.001859137687758 2369.207019114513 0.0002648944207159 0.0048821693432602 1843.0623529421337 0.0002542071675276 0.0043917760498915 1727.6365936513698 0.0004865102325063 0.0083745867844909 1721.358817336311 0.000686216347389 0.0124600028883318 1815.754307769041 0.0004967497272697 0.0099118476050088 1995.3403214708155 +r_3909 phosphatidate (1-18:0, 2-18:1) transport, cell envelope-ER membrane 4.516675687038411e-05 0.0010013567969546 2217.0216910377244 9.148670656734489e-05 0.0019090088707885 2086.651648546649 0.0001323156037632 0.0020106615841074 1519.5952154706747 0.0001945340819723 0.0029419787771924 1512.320487682041 0.0001917835217933 0.0036053736696797 1879.9183767018988 0.000278066274019 0.0045600494697896 1639.9146159944382 0.0006806180996023 0.0095662072864648 1405.5176158339823 0.0006098582234986 0.010789667557775 1769.2091607581667 0.0006759204345121 0.0120207766649727 1778.4307221972765 +r_3910 phosphatidate (1-18:1, 2-18:1) transport, cell envelope-ER membrane 6.535717956932011e-05 0.0011506153082812 1760.503307920217 0.000163398803473 0.0026028885432392 1592.9667096178655 0.0001241343038684 0.0019338253680349 1557.8492872404245 0.0001715579245438 0.0027856938919172 1623.762877362538 0.0005519523557442 0.0073634927902563 1334.0812324875565 0.0003255835832311 0.0050129245912774 1539.6736351163495 0.0003916111549072 0.0070705668528444 1805.5070097578564 0.0009861333456994 0.0144034602333904 1460.599653809901 0.0008052217560417 0.0127273350349064 1580.599994897195 +r_3911 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-16:1) transport, cell envelope-ER membrane 2.9529187505046467e-05 0.0033016066115289 11180.824433332891 1.3392382855342644e-05 0.0039166458450299 29245.324654584863 3.813239766211139e-05 0.005891765773589 15450.813834985016 2.958643327047613e-05 0.0071222291874086 24072.618427162 -0.0001338359540159 0.0164039870302583 -12256.786415031618 5.472095022598023e-05 0.0139524138620363 25497.389581901145 0.0006017325549373 0.0246078162559715 4089.493921187589 0.0001535319939351 0.0418339927938539 27247.736267610355 -0.0010271281710922 0.0401818462543637 -3912.057656021133 +r_3912 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-16:1) transport, cell envelope-ER membrane 5.1562800501562686e-05 0.0034992771154173 6786.437279160749 5.145411419839544e-05 0.0071083055549562 13814.843896735343 2.2701845141684864e-05 0.0066210200188879 29165.11841907737 0.0002012265427324 0.0074980115253655 3726.1543251456274 -0.0003348487793591 0.0142042885051961 -4242.000980974342 -0.0002184446184808 0.013394431581404 -6131.728799067728 -0.0003881711404825 0.0263773966327126 -6795.300804671821 -0.0003243682385915 0.0374463352232446 -11544.390223237124 -0.0002935549351949 0.0254234734055569 -8660.550499235995 +r_3913 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-16:1) transport, cell envelope-ER membrane 2.9561010828954948e-05 0.0035402655825517 11976.131679110498 5.341473307562552e-05 0.0076021586844259 14232.32551525196 -6.747259332681196e-05 0.0053119067616779 -7872.6880052602355 -5.970642862532961e-05 0.0086825716685434 -14542.105211196684 -0.0002010037317552 0.0156683515438061 -7795.055050462252 -0.0003283248260889 0.0122327633634307 -3725.811267197888 -5.033453773384566e-05 0.0216518875330817 -43015.96579185962 -0.0009167472054543 0.0305475428262195 -3332.166451609696 -0.0004407773241763 0.0343895826229937 -7802.030807109878 +r_3914 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-16:1) transport, cell envelope-ER membrane -4.308668232067635e-05 0.0037411843401768 -8682.925067965858 -9.419637923793616e-05 0.005775904183945 -6131.768790555513 -5.808081542899936e-05 0.0056198116417637 -9675.848385141302 -0.0001341541879475 0.0074999366893258 -5590.534894264546 -6.607748227893112e-05 0.0156868179067725 -23740.035736461872 5.520055649145588e-05 0.0139408328561502 25254.8773820932 -5.0327600969441645e-05 0.026873953996508 -53398.04298008482 -1.775343871386106e-07 0.0374261649449356 -21081079.30421112 0.0004409042046542 0.0274435258625146 6224.373814722972 +r_3915 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-18:1) transport, cell envelope-ER membrane -3.69100685648773e-05 0.0029987294424075 -8124.421218932842 -8.343727567880716e-05 0.0068539996327245 -8214.55347980097 1.1354070132289456e-05 0.0048840457003121 43015.81409491693 1.679969692265782e-05 0.0086347953744902 51398.51876044539 -0.0002009213209806 0.012529297311282 -6235.922225740197 -1.0225802160866676e-05 0.0077731722280054 -76015.2808133988 0.0002013389613576 0.0201348903523212 10000.49380236482 0.0003055824764102 0.0264650929071501 8660.54009969587 -0.0007329355519045 0.0274271438833613 -3742.094896623831 +r_3916 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-18:1) transport, cell envelope-ER membrane -2.2185440791729176e-05 0.0035003077351833 -15777.499162821408 -5.3719567070879984e-05 0.0060093541732536 -11186.527555824645 2.2708714372240284e-05 0.0027813534620089 12247.95651756048 3.348959502591873e-05 0.0071153892311875 21246.56695812757 -0.0003348575422535 0.0142044969439159 -4241.952218941495 -0.000107936762878 0.0109073903225066 -10105.352459785046 -0.0003020082048689 0.0188329855939276 -6235.918524830115 -0.0003053295207001 0.0264028793333484 -8647.339200219483 -0.0003868944686406 0.0300888496961745 -7777.017283780843 +r_3917 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-18:1) transport, cell envelope-ER membrane -2.9528435531282564e-05 0.0033016108077768 -11181.12337607282 5.37522543950553e-05 0.0038008700661997 7071.089592382464 -0.000122312584931 0.0042920336092686 -3509.069497375563 -0.0001509545803891 0.0059287290818019 -3927.492008865448 -0.0003450623699422 0.0155744009557178 -4513.5031554804345 -0.0004051680303941 0.0129399745385831 -3193.7303952621337 -0.0004900512169595 0.0236250662933063 -4820.938194967212 -0.0012044319233159 0.0400888936583493 -3328.448281906997 -0.0005870380673227 0.0359503475162656 -6124.023213728481 +r_3918 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-18:1) transport, cell envelope-ER membrane -2.952927844046436e-05 0.0033016017097965 -11180.773402415089 -0.0001479698812886 0.0054534629989262 -3685.5223180778808 -8.765979405651779e-05 0.005498741261265 -6272.820191340848 -0.0001720790008747 0.0071213519811951 -4138.420112270405 -0.000267373104299 0.0133804227050314 -5004.401149512753 -0.0002188672634077 0.0134030369290496 -6123.819853350301 -0.0003002940818754 0.021315129205847 -7098.0850081118 -0.0006111649060254 0.034163104190068 -5589.834078045824 -0.0009540531668918 0.0297983512039711 -3123.342832250149 +r_3919 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-16:1) transport, cell envelope-ER membrane 6.752644916353206e-05 0.002152094250874 3187.038971443944 5.552440783289496e-05 0.002688789371328 4842.535879752523 0.0001424234768666 0.003939056026089 2765.7350548866893 0.0001473201538999 0.0047652526067988 3234.623695841354 0.0004859561125851 0.0125333487228584 2579.1112403513325 0.0003436635652811 0.0094933184502964 2762.387232562478 0.0003134517557812 0.01233995909461 3936.79692871844 0.001089188476265 0.0285587883293048 2622.024466071825 0.001695028739352 0.0347687888819244 2051.2212020201537 +r_3920 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-16:1) transport, cell envelope-ER membrane 6.014433228555872e-05 0.0020880465098816 3471.7261469755963 0.0001659735295559 0.0046561664875395 2805.366916035347 0.0001971308366848 0.0046128267728358 2339.982343914768 7.626993013752908e-05 0.0033748924740062 4424.931906874298 0.0005237239802282 0.0127580422086872 2436.0240680839192 0.0004628924395394 0.0109543861346643 2366.5078966431533 0.0009143903070051 0.0210319476845133 2300.106149790406 0.0011084789363336 0.0286013288066867 2580.232052156742 0.000713614778046 0.0214302970423846 3003.0623946804944 +r_3921 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-16:1) transport, cell envelope-ER membrane 7.433300441727012e-05 0.0022134255753792 2977.715743808977 0.0001884697638335 0.005024850885859 2666.131045983863 0.000168596213188 0.0042406595672455 2515.275691581653 0.0002640411913707 0.0064499596793144 2442.785402470553 0.0004808851976681 0.012509630992132 2601.3757655239497 0.0004428793244246 0.0109422678425559 2470.7109226132684 0.0005090688537777 0.0159158277862296 3126.458762527045 0.0011038237150882 0.028585944656999 2589.720103514237 0.001043351155905 0.0274398779390778 2629.975323626859 +r_3922 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-16:1) transport, cell envelope-ER membrane 0.0001180700724904 0.002921727567187 2474.570825239286 0.0001755571274183 0.0047483955930958 2704.758082410555 0.0001801318993324 0.0043317403134426 2404.76025040314 0.0002445305268658 0.0062822322413388 2569.0993766125143 0.0004052033519908 0.0115709608865364 2855.5935753456547 0.0003637439671303 0.0095047148904802 2613.023376157857 0.0007836542297177 0.019174041314478 2446.7476327389327 0.0009436201027192 0.0264670903131524 2804.8459583344743 0.0003158407772587 0.0146769747060938 4646.953706699278 +r_3923 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-18:1) transport, cell envelope-ER membrane 8.3921317089806e-05 0.0023924110676667 2850.778742076476 0.0002483357967111 0.0055400907416862 2230.8868938978057 0.0001066789299939 0.0033153672120737 3107.7994616755363 0.0002377686905145 0.0060455906045159 2542.635277770074 0.0003485945683625 0.0105981303975146 3040.245419570495 0.0001247803616255 0.0055306224968249 4432.2859981926495 0.0003191736553485 0.0123464429598564 3868.25251801393 0.0003123005107146 0.0152848405881266 4894.273324481882 0.0008873370639326 0.0253879657430861 2861.141135091056 +r_3924 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-18:1) transport, cell envelope-ER membrane 0.0001105512978728 0.0027009567765985 2443.1705720054883 0.000178181476685 0.0047486009680042 2665.03626322324 2.4766226597221943e-05 0.0016122606806522 6509.916536227851 0.0001555998232737 0.0047764013886011 3069.670188633637 0.0004731181342526 0.0125253791907779 2647.4105057425345 0.0002772120399315 0.0086088451419465 3105.5091056195806 0.0005101132428022 0.0159159646130432 3120.0845768305817 0.0006166823165814 0.0215639360122925 3496.7657467185986 0.0008500843371252 0.0241333223005338 2838.932708976323 +r_3925 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) transport, cell envelope-ER membrane 9.184733763587136e-05 0.0025576019495718 2784.6228485265897 3.041919488462804e-05 0.0019045159126634 6260.901775628143 0.0001511954515124 0.0039872788586105 2637.168525060767 0.0002012727604352 0.0055598010685203 2762.3216656322425 0.0005503025097278 0.0132353912434856 2405.111917448968 0.0005267047122293 0.0117313340564933 2227.307594579466 0.0008669742501885 0.0204357225502609 2357.1314310449834 0.0016829602545594 0.0354424499251397 2105.958820424836 0.0011893969659569 0.0293424480357951 2467.002092290332 +r_3926 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) transport, cell envelope-ER membrane 8.967357916029625e-05 0.0025565237653771 2850.9219653284754 0.0002167570942606 0.0052010171911295 2399.4680353465974 0.0001918459168623 0.0045333222848841 2363.001704194316 0.000248349567274 0.0062902132360695 2532.806199387311 0.0004520396276655 0.0118326857518101 2617.62133840296 0.0004530892927968 0.0109533939786125 2417.4912435027823 0.0006194678196578 0.0173921518479763 2807.595696832434 0.0010829749984199 0.0285748555763197 2638.5517318507445 0.0011084497962961 0.0279315892248919 2519.878601468785 +r_3927 zymosteryl palmitoleate transport, ER membrane-cell envelope 4.434532953730712e-05 0.0014001103784517 3157.289376491882 0.0001917945831167 0.0039124212919604 2039.901872295961 0.0001886375870907 0.0035530493808786 1883.532033925949 0.0001990198945854 0.0043982566545295 2209.958287682768 0.000319302386772 0.0079782832949032 2498.66071329995 0.0003289031180771 0.0073349743853922 2230.132212876236 0.0007715292965263 0.0151194257405015 1959.669685723396 0.0010084387870447 0.0214645813287955 2128.496206665972 0.0003541222725917 0.0124508382097588 3515.971508551152 +r_3928 zymosteryl oleate transport, ER membrane-cell envelope 8.853324117922175e-05 0.0019778810913076 2234.0547628927006 0.0001290030198958 0.0032228058077987 2498.2405918865093 6.767605351421142e-05 0.0021393060181777 3161.097474054845 0.0002082235342284 0.0044878988712228 2155.3273926759766 0.0001562430905428 0.005529235191706 3538.867013252414 0.0001662915788096 0.0051745012604864 3111.7037299947788 0.0003390049132298 0.009895122210748 2918.8728023059707 0.0001826939918668 0.009133807039624 4999.511448784552 0.0009234540446505 0.0196944389824704 2132.6929148839085 +r_3929 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) transport, ER membrane-nucleus 0.0001107327184266 0.0020188609494999 1823.1837691552737 7.938550525484319e-05 0.0022913941759558 2886.413796322137 0.0001277491117034 0.0026676143554621 2088.166657200596 0.0002452047051007 0.004459300401864 1818.6031136846727 0.0004371795155067 0.0085225126231391 1949.430913582776 0.0004897577667682 0.0081496133108097 1664.00899869043 0.0003469797064299 0.009267448648178 2670.8906822042254 0.0008397517614446 0.0178807181843937 2129.2861778145048 0.0008072764461718 0.0171939733133744 2129.8742698252977 +r_3930 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) transport, ER membrane-nucleus 8.135701334005722e-05 0.0017294943495867 2125.808554891029 0.0001886376363423 0.00355070107051 1882.286663127408 0.0001142440813713 0.0025326759287403 2216.89902736215 0.0001688190456844 0.00374719736322 2219.6532079824865 0.000438098073285 0.0085272705383469 1946.4295915311104 0.0004666538697786 0.0079590701524984 1705.561802428207 0.0005069277852526 0.0112430014306417 2217.870426068168 0.0010229971781246 0.0195222044593763 1908.334145668307 0.0011872368279944 0.0207358995558987 1746.56808708731 +r_3931 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, ER membrane-nucleus 8.608548599868548e-05 0.0017634259587731 2048.4590849613087 0.0001343140852721 0.0030006558337938 2234.058943046866 0.0001353244012564 0.0027599665921908 2039.51879081996 0.000118817160205 0.0031338669161462 2637.554130007208 0.0007675075241286 0.0112921267267616 1471.2724464274584 0.0003260857113771 0.006650289522632 2039.4299077212409 0.0005511187988149 0.0117394129688977 2130.1057039136144 0.0013714524421447 0.0228078323238572 1663.0421604842006 0.0009536428281096 0.0186800280728595 1958.80758731102 +r_3932 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, ER membrane-nucleus 5.517085517795265e-05 0.0014015118021573 2540.3119049665293 0.0002004066051579 0.0036544992438729 1823.5423133842 0.0001929776845842 0.0033042450725195 1712.2420551572595 0.0001795542176006 0.0038380775271999 2137.559105258844 0.0005663063437357 0.0096971745631414 1712.3549242219838 0.00051048444203 0.0082788539732507 1621.764208979313 0.0008024890438916 0.0140675836207889 1752.9938542921564 0.001526162028969 0.0240849807934273 1578.1404815645878 0.0017525791213207 0.0252402258694215 1440.176113156058 +r_3933 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, ER membrane-nucleus 0.00011007272994 0.0020072571491621 1823.573513853324 0.000189171421656 0.0035451087141935 1874.019174333552 0.0002156905157064 0.0034926620255318 1619.2932795828938 0.0001733703337101 0.0037524586668651 2164.417975417934 0.0004351411120626 0.0085235811434997 1958.808512276744 0.0004102480716159 0.0074795875549573 1823.186523582208 0.0010059023354821 0.0158745259333797 1578.137894050272 0.0011407517662133 0.0208004154365209 1823.395418055508 0.0013929248406534 0.0225556427630739 1619.300776665984 +r_3934 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, ER membrane-nucleus 0.0001318345728603 0.0021669372741928 1643.6790647388502 0.0001881350450018 0.0035507815713087 1887.3578664057384 0.0001917344191269 0.0032834477775173 1712.4978355309236 0.000307333129835 0.0050375126179916 1639.104974037405 0.0003311181666245 0.0074016393411914 2235.346799798074 0.0003554638334409 0.0069628585244694 1958.8092709930424 0.000955829016785 0.0154776713102242 1619.2928900906988 0.0012919814808583 0.0221251712975212 1712.499105081708 0.0008066640532027 0.0171809709530348 2129.879332644223 +r_3935 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) transport, ER membrane-nucleus 0.0001316490837656 0.002191169405721 1664.4015613672846 0.0002543895908371 0.0041196796399099 1619.437189372625 0.000179765072497 0.0031751740669075 1766.290872193348 0.0002342540624974 0.0044212987773561 1887.3947073618715 0.0003650351884499 0.0077770071443306 2130.481496141287 0.0004919854804754 0.0081858425275723 1663.838233531039 0.0006037389333248 0.0123102200506705 2038.9972173695533 0.000992869579338 0.0194484025664376 1958.8073772392768 0.000579539663088 0.0144865529438147 2499.6654873671523 +r_3936 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, ER membrane-nucleus 0.0001535514377947 0.0023665761976541 1541.2269866317854 0.0002575217541782 0.0041273763732857 1602.7292088218242 0.0001007658496727 0.002374329851673 2356.284256405416 0.0003017766468084 0.0050210591008698 1663.832888983315 0.0004687071795737 0.0088462135419177 1887.3646334932064 0.0002462433295053 0.0057993738188688 2355.1394592166234 0.0005528635728096 0.0117753636896005 2129.885973452599 0.0005659733904074 0.0144515861025526 2553.403807933415 0.0011673154589882 0.0206084784698208 1765.4592262217268 +r_3937 lignoceric acid transport, ER membrane-ER -0.0001328278218137 0.002418713568813 -1820.93896879828 1.2536782001505378e-09 7.786835072253261e-09 621.1191254117876 1.1311841852688316e-10 7.247441900374059e-09 6406.951223996884 1.0155253782354275e-09 7.267934059698923e-09 715.6821695906463 1.3336719448470898e-09 7.90542196447282e-09 592.7561118022322 1.239143817039048e-09 7.869494096296047e-09 635.0751210703141 1.6736113708564678e-10 6.542989068360161e-09 3909.503234918748 7.317392226911526e-11 7.878893376792606e-09 10767.35144498066 2.0817465263703503e-09 9.402124235162353e-09 451.6459672713141 +r_3938 cerotic acid transport, ER membrane-ER -1.3463974845899052e-05 0.0002342692461785 -1739.9709139374777 -0.0001686987911744 0.0036069976851315 -2138.128945690777 -0.0001822580005634 0.0031069367978336 -1704.691584582704 -0.0005124709412745 0.0065647781351175 -1281.004951966767 -0.0004335087288259 0.0087857053560647 -2026.6501622375024 -3.521462980839134e-05 0.0007333546162781 -2082.5282567740774 -0.0008784168174537 0.0159754702581219 -1818.6662573730137 -0.0008738517440332 0.019145121413179 -2190.8889630195395 -0.001069348787325 0.020844908526856 -1949.3086609279565 +r_3939 ergosterol transport, ER-ER membrane 0.0002322867988396 5.817376010814202e-05 25.043937235665187 0.0003857368567301 0.0001133668355957 29.38968201192585 0.0008949197704714 0.0001887672798003 21.09320701462768 0.0013430691944697 0.0004003316955463 29.807227892260297 0.0018631159404683 0.0002759558290101 14.811522085994197 0.0022205474548123 0.0004239179233892 19.090694165106576 0.0026399460889709 0.0010835058882932 41.04272783523548 0.0029232942742905 0.0005303971121839 18.14381524462228 0.0033226681034042 0.0006887101364664 20.7276235553234 +r_3940 phosphate transport, ER-ER membrane 0.0003803101423719 0.0052597156074645 1383.006925521271 0.0005324103598624 0.0083959946845461 1576.9780826044166 0.0004696411139706 0.0072196581617362 1537.2713220733217 0.0007558363193254 0.0111346861093479 1473.161030325352 0.0014969000979975 0.0220156976406841 1470.7526354053707 0.0012326199333075 0.0181161857213745 1469.7300629206898 0.0023187648809848 0.0340109490659583 1466.7700612885285 0.0034718280777302 0.0510386086262605 1470.0788023935734 0.0030828892276787 0.0472009957059419 1531.0636296031462 +r_3941 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) transport, vacuolar membrane-Golgi membrane 0.0001328257665432 0.0031282315236903 2355.139070603852 0.000159570048595 0.0046053516191239 2886.100279891505 9.08326888011884e-05 0.0032104535023681 3534.469302560279 0.0002005839204439 0.0057875601669217 2885.355991703372 0.0002674974620746 0.0094546560246399 3534.48438400561 0.00043767669058 0.0109342583455474 2498.2500966767266 0.0006023275530266 0.0173793446404901 2885.3643757722025 0.0010689509806551 0.0285517953098899 2671.010722343095 0.0007332215187023 0.0231772631625783 3161.017860413604 +r_3942 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-16:1) transport, vacuolar membrane-Golgi membrane 0.0001323607631721 0.0031174627471264 2355.2771020750192 0.0001612261969318 0.0046518564369375 2885.2981249094623 9.083266559928324e-05 0.0032104524759052 3534.469075330742 0.0003327662290918 0.0074352287486647 2234.3699866885954 0.0004014608048436 0.0115834072208619 2885.314601352565 0.0002176711452562 0.0076938892037006 3534.63900538773 0.0006040165394842 0.0174277357932428 2885.307711627177 0.0007630692696341 0.0241207437871007 3161.0162729611834 0.0005798440554541 0.0204990610355322 3535.271396285619 +r_3943 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-16:1) transport, vacuolar membrane-Golgi membrane 8.858613811714703e-05 0.0025559844671019 2885.309735166324 0.0001854996454521 0.0049577029489048 2672.621253167346 0.000226448845098 0.0050590407872399 2234.076656496052 0.0002683638624444 0.0067043992993806 2498.249666818888 0.0007361999622407 0.015680148000357 2129.8762299080886 0.0003277421309266 0.0094564013501164 2885.3175889775093 0.0004026776150976 0.0142325342154966 3534.473653829879 0.0009137630934318 0.0263654257008133 2885.367760016617 0.0014629586783273 0.0326837981530891 2234.088948462892 +r_3944 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-16:1) transport, vacuolar membrane-Golgi membrane 0.0001033281837876 0.0027599035338977 2671.007495467798 0.0001340260779328 0.0042365723654084 3161.0060002891014 0.0001426801703465 0.003957192065676 2773.470241914856 0.0001341802762575 0.0047425695199144 3534.475894812052 0.0003343413388022 0.0105685977039295 3161.020333826927 0.0002735877142858 0.0086481456479544 3161.0138892852524 0.0010041140460821 0.022432832740181 2234.0921161006454 0.0006106059876314 0.0215817338747072 3534.4779304283747 0.0013207113704371 0.031104556490038 2355.136571569149 +r_3945 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-18:1) transport, vacuolar membrane-Golgi membrane 7.350362829448806e-05 0.0023235171431234 3161.0917678980886 0.0002150053348291 0.0053713469801742 2498.238931812091 0.0002039804697547 0.0048040654218419 2355.159505033864 0.0002760888925794 0.0067254694987307 2435.979744022009 0.0003348689140648 0.0105852512098288 3161.013389191124 0.0003282878967138 0.0094721196959092 2885.3088373722 0.0009058108621739 0.0213330831744747 2355.1366036033764 0.0010655806114643 0.0284627555347586 2671.102986347006 0.0005871101914483 0.0207512549663482 3534.47364201889 +r_3946 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-18:1) transport, vacuolar membrane-Golgi membrane 0.0001248680448566 0.0029889055558076 2393.6512814290927 0.0001878195166742 0.0050167085402123 2671.0262218992034 9.008102828770962e-05 0.0031842258395947 3534.846238016578 0.0002011835365065 0.0058047600107772 2885.305682350626 0.0004018425317051 0.0115943875879261 2885.3062264781274 0.0004360118299498 0.0108932812431165 2498.3912120847594 0.0006037011792784 0.0174186492435121 2885.3097925586057 0.0009167470427685 0.0264509742317256 2885.307832774049 0.0007338877890432 0.0231982878464235 3161.012922243234 +r_3947 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-18:1) transport, vacuolar membrane-Golgi membrane 0.0001180585725247 0.0029493972938044 2498.249157795983 0.0001343817030495 0.0042478254175523 3161.014722357869 9.083247395056204e-05 0.0032104527424635 3534.476826218522 0.0001548391383268 0.0049619111167659 3204.558724870228 0.0003346263033473 0.0105775926352838 3161.0164919711465 0.0001641620958981 0.0067005523003933 4081.6683435553314 0.0004026774547743 0.0142325300322094 3534.474022188524 0.0007632947075301 0.0241278783125956 3161.017373049543 0.0008804226892731 0.025402907644178 2885.3081541039187 +r_3948 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-18:1) transport, vacuolar membrane-Golgi membrane 0.0001180968881601 0.0029503565063307 2498.250844958694 0.0001075053789872 0.0037997505508692 3534.474820388745 9.083264533354126e-05 0.0032104519526831 3534.46928788013 0.0002345029896932 0.006263630337846 2671.0236598859133 0.0005357122921453 0.0133834268349641 2498.248972665619 0.0003283247518015 0.0094731806046134 2885.30808372862 0.0004026776280376 0.01423253102162 3534.472747089897 0.0010688783591792 0.0285498621328087 2671.011335165595 0.0011741793130764 0.0293339259539178 2498.249256074976 +r_3949 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) transport, vacuolar membrane-cell envelope 5.905732031164387e-05 0.0014753952376054 2498.242774680303 5.356341297333434e-05 0.0018931620751013 3534.4313777089133 3.4062554372149776e-05 0.001390306244817 4081.626497024489 0.0001006341815725 0.0029036016400976 2885.3035765035647 0.0001673869515192 0.0052911181692459 3161.009936091776 0.0002458835513001 0.0057908593627434 2355.1227124077545 0.0002013391801085 0.0071162657477652 3534.466438141316 0.0007639561405012 0.0170671912396621 2234.053806867101 0.0005131931458103 0.0137074643351773 2671.0146943863056 +r_3950 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) transport, vacuolar membrane-cell envelope 2.948617556339445e-05 0.0010417037580268 3532.854763708416 4.031470685747305e-05 0.0016455048759722 4081.649115767299 8.994972061933728e-05 0.0022478127922837 2498.9658409239505 0.0001005804495017 0.0029020508621641 2885.3031344961187 0.0001339478537435 0.0047343419399346 3534.4664416935 0.0001352382391297 0.0042759697716379 3161.805269835269 0.0004023097941799 0.0100507229765301 2498.254609241153 0.0002289559939297 0.0093452260002678 4081.669075295617 0.0002935552037274 0.0103756261915327 3534.4719016350373 +r_3951 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-16:1) transport, vacuolar membrane-cell envelope 4.425199177933634e-05 0.0012767989878393 2885.2915688093267 0.0001343038653101 0.0030004175614225 2234.051532689248 6.810901833873976e-05 0.0019651441583149 2885.292148157724 0.0001004162413679 0.0028973238218385 2885.313951575973 0.0003335677443789 0.0074525908904759 2234.206099379395 8.208148326307775e-05 0.0033502808806963 4081.652459859209 0.0001989770405631 0.0070341552681603 3535.159256692484 0.0001527913366597 0.0076387954080445 4999.495112118759 0.0002935553086291 0.0103756265281043 3534.470753248465 +r_3952 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-16:1) transport, vacuolar membrane-cell envelope 4.414729718464112e-05 0.0012738015040699 2885.344257299427 0.0001209425414442 0.0028483195036316 2355.101413959823 3.330070402221654e-05 0.0013599212594791 4083.761287965076 3.343585052496705e-05 0.0016716233724643 4999.494094567976 0.0001339480807898 0.0047343432094446 3534.461398421876 5.9989537815243245e-05 0.0027609112116884 4602.321191724342 0.0004530127565265 0.0106690596500424 2355.134484919614 0.0003055824892942 0.0108007257268113 3534.471412859889 0.000730822832451 0.0163282670121793 2234.2305531722604 +r_3953 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-18:1) transport, vacuolar membrane-cell envelope 2.95291998391804e-05 0.0010436855590699 3534.418693205447 4.0313228650858506e-05 0.0016454435563736 4081.64667391048 4.541649268807292e-05 0.0016052262465734 3534.456651239811 0.0001504730973694 0.0035439055964065 2355.175548560152 0.0001004609230014 0.0041004711715793 4081.6578716081367 0.0001094416803616 0.0038681845803245 3534.4711151553165 0.0003523294269479 0.0094107424612334 2671.006660656974 0.0002291869786386 0.0093546390796949 4081.662551364114 0.0004403158629684 0.0127044575275563 2885.305435490691 +r_3954 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-18:1) transport, vacuolar membrane-cell envelope 4.429122656662203e-05 0.0012778952804875 2885.2108635224367 6.717430214084413e-05 0.0021233695827644 3160.9849527165966 3.4793912273376684e-05 0.0013912493475595 3998.542436471401 8.383798857217534e-05 0.0026500620513793 3160.9322891828347 0.000100460929485 0.0041004718732399 4081.6583066254702 0.0003256525555839 0.0066425000735633 2039.750635966364 5.0334832859209824e-05 0.003559200926489 7071.049458819917 0.0009923097294749 0.0194375033964766 1958.8141503723807 7.317676192953617e-05 0.0051743599946508 7071.042579929112 +r_3955 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transport, vacuolar membrane-cell envelope 3.69111948913278e-05 0.001166758141121 3160.9871871016926 5.375296393347526e-05 0.0018998743714372 3534.455093096929 6.812460452097225e-05 0.0019655991922118 2885.299967659612 0.000100636693751 0.0029036714921045 2885.30096118574 0.0002339221270413 0.0062481492623367 2671.038153321977 0.0002461890107058 0.0057980823122048 2355.134494257288 5.033488435836092e-05 0.003559201759569 7071.0438792889445 0.0003819232349176 0.0120726380441698 3161.011674707903 0.0005137216227028 0.0137215432798325 2671.007540550439 +r_3956 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cell envelope 1.4748047645142174e-05 0.0007373213364912 4999.450464442562 6.719167148847968e-05 0.0021239122716475 3160.9754968094235 0.0001471295100841 0.0028820723757577 1958.8676493995897 5.022506507427297e-05 0.0020500144946173 4081.6562240103567 6.697167006169205e-05 0.0033482385933187 4999.484991541176 8.186705812768076e-05 0.0033415598660199 4081.690416685627 0.0003020084295055 0.0087138655479901 2885.305407619004 0.0003053666176727 0.010793099480298 3534.4726160821106 0.0005132256623064 0.0137083278096214 2671.013711203588 +r_3957 H+ transport, mitochondrion-mitochondrial membrane -0.0009188546438986 0.0073555375264191 -800.5115472029789 -0.001847502863578 0.0140930780089639 -762.8176544024197 -0.0013753058853199 0.011215138383478 -815.4650178690556 -0.0020017352079721 0.0164383702186866 -821.2060293099215 -0.0040171257121267 0.0328414695967935 -817.5365161626054 -0.0029362058135253 0.025488352500177 -868.0710453867872 -0.0066492303528667 0.0517359523158334 -778.0742968775027 -0.007896334739251 0.0695442008342718 -880.7149535921036 -0.0068181594391852 0.0635328198361161 -931.8177493911488 +r_3958 glycerol 3-phosphate transport, mitochondrion-mitochondrial membrane -4.4303695345404494e-09 7.78051244666486e-09 -175.61768574846235 -4.515460200013208e-09 7.760092103058536e-09 -171.85606249028254 -3.7901295875743926e-09 7.732262510145462e-09 -204.01050495727128 -3.334650346576935e-09 6.533465116050295e-09 -195.9265421262828 -5.375838462395932e-09 8.50862275195317e-09 -158.2752683413222 -6.329054530832873e-09 9.817287459263018e-09 -155.11459747165603 -5.411454752543433e-09 9.227556526831148e-09 -170.51896299223628 -5.125529786288199e-09 7.898027303728228e-09 -154.09192089483133 -3.004893032969157e-09 5.868368392086932e-09 -195.29375347808485 +r_3959 CMP transport, mitochondrion-mitochondrial membrane -0.0003062797913291 0.0024518460114127 -800.5249059274515 -0.0006158243445773 0.0046976923763057 -762.8299234467154 -0.0004584261023026 0.0037383794734049 -815.481373034265 -0.0006672376244885 0.0054794567043388 -821.2151867992964 -0.0013390316666103 0.0109471564343991 -817.5427592471051 -0.0009787272595611 0.0084961172327278 -868.0781238827491 -0.0022163997507481 0.0172453175901341 -778.0779430386045 -0.0026321026324048 0.0231814005045349 -880.717956022671 -0.002272713493224 0.0211776066911007 -931.8203440178752 +r_3960 CTP transport, mitochondrion-mitochondrial membrane 0.0003062797913291 0.0024518460114127 800.5249059274515 0.0006158243445773 0.0046976923763057 762.8299234467154 0.0004584261023026 0.0037383794734049 815.481373034265 0.0006672376244885 0.0054794567043388 821.2151867992964 0.0013390316666103 0.0109471564343991 817.5427592471051 0.0009787272595611 0.0084961172327278 868.0781238827491 0.0022163997507481 0.0172453175901341 778.0779430386045 0.0026321026324048 0.0231814005045349 880.717956022671 0.002272713493224 0.0211776066911007 931.8203440178752 +r_3961 phosphate transport, mitochondrion-mitochondrial membrane -0.0003062844290103 0.0024518459303576 -800.5127581183211 -0.0006158322451163 0.0046976928075188 -762.8202070892814 -0.0004584332408013 0.0037383794801786 -815.4686762338008 -0.0006672440662713 0.0054794566092022 -821.2072442730368 -0.0013390394137413 0.010947156638011 -817.5380444869995 -0.0009787336936957 0.0084961174883609 -868.0724433097772 -0.0022164083180835 0.0172453174805725 -778.0749305021629 -0.0026321100679059 0.0231814004115424 -880.7154645316471 -0.0022727193401009 0.021177606652778 -931.817945098208 +r_3962 diphosphate transport, mitochondrion-mitochondrial membrane -0.0003062797869291 0.0024518460119625 -800.5249176072334 -0.0006158243337511 0.0046976923777252 -762.8299370878456 -0.0004584260892152 0.0037383794750101 -815.4813966652566 -0.0006672376299687 0.0054794567036714 -821.2151799544646 -0.0013390316577233 0.0109471564354868 -817.5427647542772 -0.0009787272484806 0.0084961172340045 -868.0781338410504 -0.0022163997308681 0.0172453175926895 -778.07795013288 -0.0026321026224452 0.0231814005056654 -880.7179593981564 -0.0022727134747072 0.0211776066930882 -931.820351697264 +r_3963 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) [cytoplasm] SLIME rxn 4.934745715995156e-06 2.5052692841713736e-05 507.6795094124021 7.97968545102322e-06 4.327343534652688e-05 542.2950016278901 2.179878017180334e-05 0.0001099257961722 504.2749883522192 2.6520284388152147e-05 0.000142914692508 538.8882351952562 3.794171879204877e-05 0.0002013773004742 530.7542907531604 4.672403922961821e-05 0.0002420485274731 518.0385331920254 4.192095949491286e-05 0.0002471466201611 589.5538249574743 6.052660935986626e-05 0.0003274077604373 540.9319370439407 5.858448820145166e-05 0.0003342792762652 570.5934907475587 +r_3964 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) [cytoplasm] SLIME rxn 0.0001807067281002 4.620754342070495e-05 25.57046099305509 0.0002920891361392 7.93851889522096e-05 27.17841204281024 0.0006862496548967 0.0001721572279928 25.08667607545064 0.0010253247436544 0.0002412610027233 23.53020389066496 0.0014439597803965 0.0003478088174641 24.08715410124509 0.0016887095727282 0.0004526559882154 26.80484528101081 0.0019307390369551 0.0004405430955498 22.81732989895149 0.0022482699812158 0.0005517312966915 24.54025990211192 0.0025449915478321 0.0006327778979022 24.863654201181568 +r_3965 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) [cytoplasm] SLIME rxn 3.041823951248119e-06 2.098253181553544e-05 689.8009928196501 7.752003510039505e-06 4.315285688026968e-05 556.667148362137 1.0625824083167785e-05 7.62399690596483e-05 717.4970003542495 1.8543189111716604e-05 0.0001195914040526 644.9343925264328 2.6276630054885266e-05 0.0001772789941323 674.6641169817211 2.8908434476258263e-05 0.000196457187278 679.5843179933015 2.286442749980336e-05 0.000189406048818 828.3874539159161 3.5632861204061366e-05 0.0002558867672896 718.1201807631518 4.414021944999392e-05 0.0003048329221054 690.6012835997909 +r_3966 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) [cytoplasm] SLIME rxn 6.130530968296101e-07 1.0352406792645706e-05 1688.6639748144062 7.416793336656185e-07 1.508305120531079e-05 2033.6350927786389 1.6059971054552094e-06 3.206347068816175e-05 1996.4837158952143 3.904997633601339e-06 5.977568460552595e-05 1530.7482926794637 4.880295218212097e-06 8.112652453589886e-05 1662.3282180379997 8.991317687966099e-06 0.0001222066307589 1359.1626388927418 7.881070492053805e-06 0.0001231717851885 1562.8814044068345 7.044080579496549e-06 0.0001250588386451 1775.3749014341993 1.0492630590615302e-05 0.0001622479369186 1546.3037178090456 +r_3967 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) [cytoplasm] SLIME rxn 1.2872563701504435e-06 1.2843626164219747e-05 997.7519989059128 1.6934486511216766e-06 1.768455423773728e-05 1044.2923218264514 2.4139980900342203e-06 3.534027363303168e-05 1463.9727255347873 5.95192879392902e-06 7.254121619811885e-05 1218.7850142312027 4.103553316853963e-06 6.794118446743749e-05 1655.6671553015278 9.79776371705693e-06 9.902037488044404e-05 1010.6426092727612 8.988761979068671e-06 0.0001189961446907 1323.832413939197 7.533167365910078e-06 0.0001098985809018 1458.8628602515605 1.2750807167858472e-05 0.0001673324924701 1312.3286256886015 +r_3968 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) [cytoplasm] SLIME rxn 1.1568297629036546e-06 1.4389835550793408e-05 1243.9026045348949 4.531937330121712e-07 1.019591491154802e-05 2249.791682638778 3.0299459582157914e-06 4.561874024106675e-05 1505.595838017181 2.9312813993370778e-06 5.321291331101238e-05 1815.3464666697205 5.608238859211339e-06 8.96169826200946e-05 1597.9523139051362 1.0853522510107834e-05 0.0001353406000946 1246.973965996829 7.774789612275584e-06 0.0001226572547425 1577.6279598468225 1.126839365121868e-05 0.0001592469538052 1413.2178794447057 1.4816674893095902e-05 0.0001964011999801 1325.5416711047535 +r_3969 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) [cytoplasm] SLIME rxn 1.821128673068504e-06 1.649905887302073e-05 905.979852879956 3.8545855397770185e-06 3.2180340656100496e-05 834.8586462544057 7.45740337438566e-06 6.842971829819838e-05 917.6078436797128 7.033187991298311e-06 8.066230562219313e-05 1146.8811259131871 1.3855616959306006e-05 0.0001362474453245 983.3372683776032 1.973492577782414e-05 0.0001704333821912 863.6129880088918 1.9737321349042253e-05 0.0001862909282041 943.8511179389318 2.312320026270466e-05 0.0002193577722192 948.647980068149 2.589090976546436e-05 0.0002491024696249 962.1232775576368 +r_3970 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) [cytoplasm] SLIME rxn 5.477198935512928e-07 8.404769334954173e-06 1534.5013818029386 1.5322974561241138e-06 1.796161955640197e-05 1172.20187794576 1.3786334616076654e-06 2.972230588712597e-05 2155.925176258663 1.8645012544808663e-06 4.016652334746544e-05 2154.2770888963023 3.0283378057093e-06 6.0780138111037984e-05 2007.04617551086 1.0078778355808438e-05 0.0001095673173922 1087.1091071185965 3.3197337765212165e-06 6.696688682995329e-05 2017.236662276232 5.805380553986138e-06 0.0001072551668761 1847.5131109624967 8.211979612924841e-06 0.0001329588171387 1619.0836242396194 +r_3971 ergosteryl palmitoleate [endoplasmic reticulum membrane] SLIME rxn 5.488734473457181e-06 3.461534277407615e-05 630.6616386978006 5.163902990929025e-06 4.3417118975916455e-05 840.7810730020199 1.867129182529464e-05 0.0001261934436213 675.8688407966508 2.491140542997896e-05 0.0001775685124335 712.8000583214996 3.629599609380912e-05 0.0002566352817636 707.0622365629415 5.226177288740895e-05 0.000333602494938 638.3298470505279 4.655809796000317e-05 0.0003363246124407 722.3761862644304 5.602578272826969e-05 0.0003964653249062 707.6479891930428 5.789492851807675e-05 0.0004325594837167 747.145725521818 +r_3972 ergosteryl oleate [endoplasmic reticulum membrane] SLIME rxn 0.0002285956397621 3.311880476344084e-05 14.487942463776433 0.0003760363052573 4.150570676679543e-05 11.037686038955128 0.0008668405337626 0.0001207776120984 13.933083121323788 0.0012913046550811 0.0001698550725785 13.15375669948742 0.0018196388866901 0.0002454065128187 13.486550249823573 0.0021478479173885 0.0003193557362382 14.868638214687412 0.0024160524034271 0.0003216234142797 13.3119386741571 0.0028361303657512 0.0003786280429422 13.35016357197481 0.0032212106753744 0.0004136837370421 12.84249242698467 +r_3973 ergosterol ester transport, ER membrane-cytoplasm 0.000154601136484 1.142279867913823e-06 0.738856061405286 0.0002518697318674 1.5538880080201411e-06 0.6169411451304246 0.0005848953635101 1.6479754558046895e-06 0.2817556025602188 0.000869462424635 2.3539316964899343e-06 0.2707341490321522 0.0012259556042565 5.161831509228249e-06 0.4210455493907082 0.0014530445050951 4.2321725396162685e-06 0.291262416586411 0.0016267459627921 7.685839513439536e-06 0.4724671023770369 0.0019104565223431 1.121509580718756e-05 0.5870374790540903 0.0021662195628946 1.090612035379058e-05 0.5034632934076733 +r_3975 palmitate [cytoplasm] SLIME rxn 4.407040162781946e-06 2.149398336561149e-05 487.7192530971491 4.876435065638614e-06 3.142848532877163e-05 644.4971563392648 1.664051555721263e-05 8.846530505237251e-05 531.6259868765202 1.7440162972121467e-05 0.0001081594289563 620.1744165420063 2.925733461571915e-05 0.000169517451753 579.4015551298094 3.577877905779071e-05 0.0001989518701985 556.0610938602301 3.873950031916425e-05 0.0002250912658741 581.0381239295824 4.7354764652652775e-05 0.000268934294854 567.9139086143417 4.756579979027156e-05 0.0002868715143466 603.1045743191468 +r_3976 palmitoleate [cytoplasm] SLIME rxn 0.00012771846138 2.323564031971613e-05 18.1928595667733 0.0002103558912599 3.4404017293273975e-05 16.355147976699744 0.0004822696555508 9.668067002927148e-05 20.04701496693594 0.0007262061702202 0.0001167935614475 16.082700235411995 0.0010156077509555 0.0001899792279331 18.70596475405231 0.0012029436192565 0.000222758280347 18.517765652615427 0.0013482094662192 0.0002518247307105 18.678457392582377 0.0015833253168199 0.0002949915618847 18.631140344377016 0.0018034210373913 0.0003129061853977 17.350700635628634 +r_3977 stearate [cytoplasm] SLIME rxn 2.711642647105975e-07 5.263058517692435e-06 1940.91154426616 5.983786771486256e-07 1.0307254887341209e-05 1722.530444509988 1.693331222646035e-06 2.5620447897701955e-05 1513.020462568859 1.8783628064754083e-06 3.404399588083114e-05 1812.4291943744283 5.270822359017468e-06 6.81011556155807e-05 1292.040425135394 6.377494849726936e-06 8.045160810046705e-05 1261.4923256882244 6.892422380974163e-06 8.744068033403502e-05 1268.6494747536976 5.652858896562795e-06 8.698240901309352e-05 1538.7330659532815 5.853401433782608e-06 9.434306017125792e-05 1611.7647360859576 +r_3978 oleate [cytoplasm] SLIME rxn 1.9560807773745746e-07 4.792431392036142e-06 2450.01711967564 1.9638319568351889e-07 6.1815816275244885e-06 3147.7141442826965 9.27092815211817e-07 1.988800004862542e-05 2145.2005368072582 2.702915240038736e-07 1.351516948564312e-05 5000.219498355203 1.0268945555640948e-06 3.052218920646705e-05 2972.2807508411192 7.96534386080242e-07 2.830523016600868e-05 3553.5478016585257 1.0191081697633533e-06 3.260189246662849e-05 3199.0610451291896 1.9842016170121315e-06 5.231292924144943e-05 2636.472462925605 1.054301174000242e-06 3.74706175708279e-05 3554.0715020411512 +r_3979 phosphatidyl-L-serine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 5.8489439471073854e-06 3.052332111697138e-05 521.8603801472022 8.692908638560132e-06 4.893704623732659e-05 562.9536473010992 2.1406749661322465e-05 0.0001178677466487 550.6101977811951 1.8935577378776386e-05 0.0001327927541446 701.2870613253473 3.52282956106408e-05 0.0002174134158203 617.1556473332421 4.677483164583846e-05 0.0002614821673957 559.0232143978155 3.6770366316887965e-05 0.0002577552756656 700.9864232635564 4.72556179655945e-05 0.0003187297026926 674.4800225122516 5.652200683293905e-05 0.0003679253253005 650.9417232618579 +r_3980 phosphatidyl-L-serine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 0.0001721478473803 4.538498289176612e-05 26.363956089143898 0.0002882746718578 5.875820678277666e-05 20.382715694062767 0.000662184457686 0.0001510114207016 22.80503852799018 0.0009994606951576 0.0001874289838528 18.75301197545317 0.0014004360261779 0.0002885757022249 20.6061324352364 0.0016346739091481 0.000394864373884 24.15554390844028 0.0018711642293589 0.0003542686539256 18.93306041057985 0.002186891704799 0.0004442471762269 20.314091239731525 0.0024773674468637 0.0005019597428743 20.26182040576072 +r_3981 phosphatidyl-L-serine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 2.251172292172568e-06 1.795137755683204e-05 797.423529920381 3.367948157823207e-07 9.495783887436542e-06 2819.456666926226 3.193725914767003e-06 3.730199818448536e-05 1167.9774401431912 4.523352905105459e-06 5.053551135797092e-05 1117.2135453091012 6.974536042019832e-06 7.69695314070799e-05 1103.579233706124 1.750266138791435e-05 0.0001505456535698 860.1300695551465 7.614496700112282e-06 9.290915808114422e-05 1220.1615121820748 8.99654276978445e-06 0.0001096328669914 1218.6110797986964 1.2641609906191362e-05 0.0001336584600733 1057.289863119923 +r_3982 phosphatidyl-L-serine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 7.263667095986499e-07 1.1136467291299215e-05 1533.1742416241254 7.576291266281741e-07 1.441708928616032e-05 1902.921730362127 1.623776155496607e-06 3.222330027113568e-05 1984.4668960101017 4.050418186995331e-06 6.135967297281907e-05 1514.89723134827 4.286971705567216e-06 7.71861729896486e-05 1800.482445205128 4.688453552975162e-06 8.82877596289864e-05 1883.0891386982269 5.840544405866498e-06 0.0001010099297316 1729.4608637882366 5.019038058242737e-06 0.0001037203466796 2066.538358069573 8.298640960675771e-06 0.0001392564035149 1678.062759611351 +r_3983 phosphatidyl-L-serine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 1.6928923440577989e-06 1.6026028261686423e-05 946.665528847076 1.0373941629764623e-06 1.641101761183402e-05 1581.946206902494 4.446161843755538e-06 5.330784581248732e-05 1198.9632335889014 4.838586178497311e-06 6.723067324704017e-05 1389.4693773526956 7.41262627809314e-06 9.673850884038596e-05 1305.0503992934532 1.2488851260878044e-05 0.0001294663770635 1036.6556087440802 9.229337903012007e-06 0.000127968219982 1386.5373803283012 1.3275216379271184e-05 0.0001655195277654 1246.8311102177536 1.2515883975936417e-05 0.00016865858954 1347.5563521067445 +r_3984 phosphatidyl-L-serine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 6.901603678149244e-07 1.053277465749424e-05 1526.1343810339952 8.722594850220592e-07 1.5244174816779273e-05 1747.6651247184489 2.767469453482287e-06 4.258064204911016e-05 1538.6129012383944 3.086496423332301e-06 5.486652507901024e-05 1777.631254138121 3.725399120778597e-06 7.009274517875244e-05 1881.482839994424 5.561981601289565e-06 8.816381674704835e-05 1585.1152173284297 4.099708652332738e-06 8.507648108314589e-05 2075.1835873687587 1.1796524340866043e-05 0.0001571229920759 1331.9431006607338 6.825733072711199e-06 0.0001275843442959 1869.1669149211448 +r_3985 phosphatidyl-L-serine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 8.381064320352517e-07 1.1488060400424802e-05 1370.7161717548545 7.110797368772435e-12 2.5939045930416554e-10 3647.839276693454 8.674920097996577e-07 2.3283706165940563e-05 2684.0254322708747 8.699860338712099e-07 2.5894683147798723e-05 2976.4481428022664 2.3202786571227944e-06 5.43442476062218e-05 2342.143149030646 7.959173868144907e-06 0.0001099015532657 1380.8160882824588 4.046204245557838e-06 8.247310260247401e-05 2038.2832303390976 2.19098310445172e-06 6.465912806722388e-05 2951.146813311664 6.49240059406236e-06 0.0001207772087422 1860.2858371477623 +r_3986 phosphatidyl-L-serine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 1.757132280757513e-07 4.6375929071304914e-06 2639.296402392192 7.099644781656058e-07 1.1340289238402231e-05 1597.3037507035676 1.491033615748174e-06 2.9913507439361404e-05 2006.2262261170645 1.949760405985395e-06 4.2040313900633335e-05 2156.1784602650428 2.7309689964220087e-06 5.780918436829604e-05 2116.8011956208584 3.4777768015685065e-06 6.874937486702643e-05 1976.819640524944 2.805152412682961e-06 6.788111729068126e-05 2419.872695108108 4.557415630325786e-06 9.499261232572738e-05 2084.352625063009 4.437481869523413e-06 9.775022086445142e-05 2202.8308788324093 +r_3987 phosphatidyl-L-serine transport, ER membrane-cytoplasm 0.0001351788874672 9.98777403791934e-07 0.7388560614052401 0.0002202278127757 1.3586759900341392e-06 0.6169411451303637 0.0005114160627933 1.440943409313065e-06 0.281755602560229 0.0007602335010574 2.0582116997451813e-06 0.270734149032132 0.0010719411152887 4.513360358012731e-06 0.4210455493907358 0.0012705012660719 3.700492690322316e-06 0.2912624165864246 0.001422380937444 6.720281999904661e-06 0.4724671023769962 0.0016704494748101 9.806164485799868e-06 0.587037479054202 0.0018940814872478 9.536005035522272e-06 0.5034632934076428 +r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 0.00028655769294 9.187144263548544e-05 32.06036511981082 0.0004710318762279 0.0001376887616515 29.23130441916942 0.0010720933368217 0.0003624007177786 33.8030939407743 0.0016399849656858 0.0005082564481657 30.991530946942923 0.0022932524809 0.0007640118923078 33.31564660546836 0.0026786379838945 0.0008794403954813 32.83162565337413 0.0030916164861075 0.0009957937292633 32.20948438262109 0.0035804790985105 0.0011877219358467 33.172151077235654 0.0039847946453179 0.0013054386915868 32.76050104917499 +r_3989 phosphatidylcholine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 3.682878528257178e-05 9.37691149202366e-05 254.60822071861887 5.563972849167567e-05 0.0001425439315602 256.1909186555532 0.0001426099014249 0.0003347695621159 234.7449642492735 0.0001794046763125 0.0004546571196233 253.4254563305452 0.0002671723069544 0.0006927300505071 259.2821308479799 0.0003835589545148 0.0008676390541025 226.2074822890919 0.0003492502937531 0.0009250306767527 264.86181781324285 0.0004312362989803 0.0011231640801789 260.45211936814206 0.0005291140763799 0.001237738485175 233.92658415806977 +r_3990 phosphatidylcholine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 1.7658254489281956e-05 2.8507206323796925e-05 161.43841590401794 2.5764138585168893e-05 4.274092364454721e-05 165.89308236818363 6.892781367645756e-05 0.0001063463142856 154.28650440708913 9.234907269371028e-05 0.0001593190668196 172.5183179131932 0.0001416948821992 0.0002291264243063 161.70409315428364 0.0001625237003135 0.0002730774515407 168.02315663123056 0.0001649946381046 0.0003002369484645 181.96770023164967 0.0002133808103986 0.0003503682944355 164.1985958254154 0.0002878632107814 0.0004126473863064 143.34842760433654 +r_3991 phosphatidylcholine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 4.8613243566496524e-06 3.509638602599737e-05 721.951127947061 4.424658731013566e-06 3.902277689713006e-05 881.938682041384 1.718276450552405e-05 0.0001249649606924 727.2692391978873 2.491724627295207e-05 0.000171323349799 687.5693562694902 3.343261023188653e-05 0.0002503081921413 748.6947336904693 4.1063264032268376e-05 0.0003137005473252 763.9445005607207 4.3865009051216944e-05 0.0003270262398062 745.5287184014117 5.202048633942059e-05 0.0003831846113516 736.6032851970515 7.096156056478918e-05 0.0004680114527053 659.5281290044919 +r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 0.0003839833598644 0.0001258238323892 32.768042978127475 0.0006354583626537 0.0001921394988881 30.236363258438832 0.0014711412924231 0.0004694447663635 31.9102433451694 0.0021829880907698 0.0006658397476281 30.50130005030554 0.003055347431511 0.0009580549477889 31.35666137042717 0.0036551130666608 0.0011570557349582 31.6558123881857 0.0040357451642388 0.0012612275519983 31.25141704124968 0.0047523812305621 0.0015214265280829 32.01398318591945 0.0055012611362353 0.0017204226634159 31.27324118617154 +r_3993 phosphatidylcholine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 2.898878498884916e-05 7.036809405186147e-05 242.7424746464169 4.499045887968093e-05 0.0001046706825348 232.65084451518413 0.000102472869634 0.0002781714888981 271.4586698815268 0.0001436962431296 0.0003280680701962 228.30664396727195 0.0002243545937433 0.000521823487265 232.58872419698952 0.0002065390105742 0.0005606171719908 271.4340358425404 0.0002745557322375 0.0006002576176543 218.62869617124608 0.0003379010391431 0.0007940729189522 235.00162087866207 0.000310447745137 0.0008510459142444 274.1349961710091 +r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 2.1689793424185987e-05 2.9527751043738536e-05 136.13661719254807 3.538404441606252e-05 4.492606800804325e-05 126.96702355383982 7.860611601381872e-05 0.0001113001302006 141.59220152930968 0.0001249369277526 0.0001654893359504 132.45830430390885 0.000172677067305 0.0002389675264998 138.38984540881617 0.0002113267295663 0.0002895337566338 137.0076361035611 0.0002520523997129 0.0003209692515349 127.3422716469038 0.0002782792877539 0.0003797673448645 136.4698565709892 0.0002589653230445 0.0004013595847754 154.98584136931453 +r_3995 phosphatidylcholine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 2.209258733856068e-06 1.749996209105253e-05 792.1191765759313 2.419576268466228e-06 2.498628216404056e-05 1032.671814882669 8.151207237058316e-06 6.632824052676899e-05 813.7229075126072 1.3623534868811447e-05 0.0001040046497782 763.4189715059762 1.8989917158700665e-05 0.0001455447832118 766.4319017063475 1.879080532941832e-05 0.0001628625293346 866.7139405659583 2.468585834880301e-05 0.0002005025030628 812.2160478676026 2.735481656490664e-05 0.0002297559181576 839.9102864116322 2.5453510879663743e-05 0.0002130128335045 836.8701453864338 +r_3996 phosphatidylcholine transport, ER membrane-cytoplasm 0.0005856888572415 4.327397622704434e-06 0.7388560614052546 0.0009541798901745 5.88672834104652e-06 0.6169411451303869 0.0022158096948751 6.243167957383601e-06 0.2817556025602295 0.0032938597055626 8.917603044166375e-06 0.2707341490321019 0.0046443936520472 1.955501276813089e-05 0.4210455493907401 0.0055046941766699 1.6033105284659968e-05 0.2912624165864056 0.006162742432804 2.9116930599228872e-05 0.4724671023770286 0.0072375476844964 4.2487117472412245e-05 0.5870374790541839 0.0082064769327032 4.131659903812915e-05 0.5034632934076787 +r_3997 phosphatidylethanolamine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 6.137452962180825e-06 2.979959765957591e-05 485.5368805789951 7.635750733563943e-06 4.211811756744012e-05 551.5910489626699 1.9988561167224528e-05 0.0001042667633807 521.6321600560763 2.7270871958701147e-05 0.0001536832635507 563.5436365346025 4.128372125605545e-05 0.0002118693702731 513.2031799145956 4.725789738366728e-05 0.0002526216064839 534.5595561162039 4.808484826771812e-05 0.0002688855561024 559.1897776309568 6.451018440499139e-05 0.0003421695597396 530.4116906432631 7.599405039894617e-05 0.0004066620025997 535.1234740942394 +r_3998 phosphatidylethanolamine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 8.640864347276481e-05 4.889033748342136e-05 56.58037844192187 0.0001353952131332 7.201286531286066e-05 53.18715754152945 0.0003176955012219 0.0001698072123142 53.44967481790987 0.0004691940519092 0.0002541504237421 54.16744366385928 0.0006703959582595 0.0003622797082022 54.03966174598728 0.0008192759946755 0.0004604407680736 56.20093485785613 0.0008746534481628 0.0004691776063885 53.64154310189932 0.0010419808507202 0.000558606185655 53.61002414477283 0.0011755143699064 0.0006368585582765 54.17701174739804 +r_3999 phosphatidylethanolamine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 0.0001249631107001 5.201442103273647e-05 41.62382061499271 0.000210686337888 7.703373882744105e-05 36.56323404717933 0.0004831255795505 0.0001884704583552 39.01065609702751 0.0007183087065198 0.000280978634013 39.11669613115856 0.0010037990242829 0.000402512635276 40.09892673123201 0.001172195791693 0.000491693689951 41.9463790465308 0.0013395176651677 0.0005283796398014 39.44551487010724 0.0015652884473672 0.0006277390015766 40.1037267369123 0.0017792951785703 0.000710263518049 39.918251148170015 +r_4000 phosphatidylethanolamine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 3.3571787297962182e-06 2.6868070096319063e-05 800.3169404671512 4.642369874514589e-06 3.9788558685913205e-05 857.0742909638051 1.1125311821993097e-05 9.510750983092524e-05 854.8750035294452 1.868319818042491e-05 0.0001495333518925 800.3627133240176 2.942471080290902e-05 0.0002229426460377 757.6714943132451 2.9195323847477644e-05 0.0002414936834505 827.1656266329709 3.672684736522504e-05 0.0002870971983282 781.7093459539424 3.603686128826014e-05 0.0003088924665719 857.156965200576 5.205122527640078e-05 0.0003929739130344 754.9753362149336 +r_4001 phosphatidylethanolamine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 7.63216011278137e-07 1.1151645941915284e-05 1461.1388882211638 1.5538303252687776e-06 2.0414947377824937e-05 1313.846630860008 2.482840778449797e-06 3.9508875121185575e-05 1591.2770349234231 4.2210286949423725e-06 6.172170303561478e-05 1462.2431519968009 7.512179543642691e-06 0.0001004442976057 1337.0859551778892 1.0115704240484742e-05 0.000122897439252 1214.917284357156 9.632221572783311e-06 0.0001290617251335 1339.8957255946318 1.1994787922034688e-05 0.00015822408524 1319.1069843707935 1.125785312850905e-05 0.0001610081061507 1430.1848168817623 +r_4002 phosphatidylethanolamine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 2.499846522500736e-07 7.340258083829614e-06 2936.283494911017 4.408536791807744e-07 1.1834916418185302e-05 2684.545230557628 3.324893617206019e-07 1.662303029433384e-05 4999.567567609138 1.494901237819336e-06 4.310006668377217e-05 2883.138069150556 5.399436748571811e-07 2.756418616062293e-05 5105.01140103435 7.213302915487075e-07 3.232534556466639e-05 4481.3514617919855 3.163184087868105e-06 7.960582135954897e-05 2516.6357426007726 3.531206824670933e-06 9.253007939983856e-05 2620.352870677895 6.567997799223504e-07 4.361301130778712e-05 6640.229281584599 +r_4003 phosphatidylethanolamine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 7.714124998627048e-07 1.0120680744106072e-05 1311.9674293464702 1.6927930801588526e-06 1.973656473309476e-05 1165.917143945477 6.254919311273205e-06 6.386810502680379e-05 1021.0859940542266 1.021180786520007e-05 9.985467210486862e-05 977.8353982271316 1.0115358608234318e-05 0.000118353174923 1170.0343952882508 1.183743371601526e-05 0.0001222172492233 1032.4640640478988 2.3593601741359112e-05 0.0002068259049271 876.6186154807164 2.142162786385764e-05 0.0002133916275941 996.1503810558468 1.9687079750340368e-05 0.0002169518512517 1102.0011804849366 +r_4004 phosphatidylethanolamine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 3.997490616793529e-07 5.822449523749023e-06 1456.5261264876544 9.887707986264869e-07 1.2292116117590724e-05 1243.171434134771 2.179753313713837e-06 2.178485076795326e-05 999.41817410689 3.762411448104304e-06 3.869735483491173e-05 1028.5253319226808 4.564596139569975e-06 4.7172302525169725e-05 1033.4386894875165 5.421395571558225e-06 6.607429195288681e-05 1218.7690619649 8.759419497924242e-06 7.755323472744935e-05 885.3695698194097 9.383723612722866e-06 8.840644602668207e-05 942.1254256339852 8.543082448067963e-06 9.202907870566362e-05 1077.2350526299344 +r_4005 phosphatidylethanolamine transport, ER membrane-cytoplasm 0.0001574065758039 1.1630080263779302e-06 0.7388560614052856 0.0002564402367508 1.582085333185968e-06 0.6169411451304517 0.0005955090529573 1.6778801204602709e-06 0.2817556025601673 0.0008852399546631 2.396646858149569e-06 0.27073414903211 0.0012482021681232 5.255499676280907e-06 0.4210455493906811 0.0014794118933361 4.308970831797327e-06 0.29126241658639 0.0016562653906003 7.825309098643369e-06 0.4724671023770351 0.0019451242483937 1.14186083522411e-05 0.5870374790541182 0.0022055284429944 1.110402613614095e-05 0.5034632934075928 +r_4006 triglyceride (1-16:0, 2-16:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn 3.5076740016864587e-06 2.29659585229327e-05 654.7346906209319 4.729144615483629e-06 3.4145366179221845e-05 722.0199202077044 1.4240810654001606e-05 9.36545925287072e-05 657.6493066593134 1.545673755553792e-05 0.0001134079028118 733.7117707044141 3.105471067707345e-05 0.0002011106474665 647.6010984544306 3.333476304570889e-05 0.0002182356585376 654.6788955373412 3.686944123176456e-05 0.0002448707311693 664.1563392026908 4.6933772753190185e-05 0.0003050719310076 650.0051308722279 5.143353997183235e-05 0.0003400431846286 661.1312089638119 +r_4007 triglyceride (1-16:0, 2-18:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn 9.843950613467552e-07 1.0384516957538843e-05 1054.913557096857 1.6438995945504412e-06 1.831764017169495e-05 1114.2797426569286 3.7873750286103e-06 3.963078128498346e-05 1046.3917881278624 6.387829525690652e-06 6.858676313978223e-05 1073.7099802669927 1.027874621087833e-05 0.0001054172278318 1025.5844990144774 1.2999502981069755e-05 0.0001246744384959 959.0708096878092 1.5440332868456395e-05 0.0001466919335418 950.0568076578936 1.3873603838512443e-05 0.0001447919787472 1043.6508093543948 1.589126672060604e-05 0.0001610610901287 1013.51951962317 +r_4008 triglyceride (1-16:1, 2-16:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn 1.7838879302823434e-06 1.7238542673517048e-05 966.3467295722234 3.11514128486589e-06 2.999694961351293e-05 962.9402608236544 5.513919165786389e-06 5.985084715349319e-05 1085.4502098047594 7.747547540344826e-06 8.316817374217156e-05 1073.477423779318 1.721753245302832e-05 0.0001524267223121 885.2994627888329 1.8684077308809032e-05 0.0001714374259863 917.5589629224344 1.905075937449561e-05 0.0001863863862347 978.3672271050208 2.749359106059465e-05 0.0002418342780962 879.6023682873573 2.6010843638962905e-05 0.000244626906236 940.4804766487551 +r_4009 triglyceride (1-16:1, 2-18:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn 1.8719168894181642e-07 5.9134622541784985e-06 3159.0410277330966 2.040783959006512e-07 7.764768700096842e-06 3804.797007458282 2.059472585802143e-06 3.785019530859146e-05 1837.8586619471407 1.875716471068248e-06 4.3071321264669965e-05 2296.259692177264 4.418379260148524e-06 8.066671169526941e-05 1825.7081827004088 5.143965910578339e-06 9.255648469596822e-05 1799.3215022212703 5.27227872824578e-06 0.0001010921545085 1917.428112572167 5.972153095394815e-06 0.0001172257047754 1962.8717298938864 6.989622094357135e-06 0.0001346507767189 1926.438581387849 +r_4010 triglyceride (1-18:0, 2-16:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn 4.829056818673447e-07 8.307530002267487e-06 1720.3214445817152 9.59108171006457e-07 1.589046606503989e-05 1656.7960262881452 1.7194491524988537e-06 3.0101592816146783e-05 1750.6532701127287 3.414581443587754e-06 5.607751004639794e-05 1642.2952848790871 3.7094567517101856e-06 6.403282813509126e-05 1726.2050057753054 4.457724766619049e-06 8.159487210785421e-05 1830.415209096448 4.562333106928858e-06 8.316597254576643e-05 1822.88251639192 4.959297070787883e-06 9.31306356124146e-05 1877.8999177320693 6.671085379768531e-06 0.0001178085037267 1765.9570672569323 +r_4011 triglyceride (1-18:0, 2-18:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn 4.649036968133322e-07 8.19235096818647e-06 1762.1608570421536 3.266177153696864e-07 6.8204321688046014e-06 2088.200317329637 9.493969898568831e-07 2.3750204719238792e-05 2501.60943977914 1.6798264173496162e-06 3.705375782647718e-05 2205.8087337940296 2.024334426660435e-06 4.809934248064556e-05 2376.057130046221 2.615859703293688e-06 5.801932118469035e-05 2217.982910613934 2.2088088085897388e-06 5.399883770562504e-05 2444.7040185475244 1.777358012679867e-06 5.182629281636656e-05 2915.917471135928 5.891759127423207e-06 0.0001083417395994 1838.8691264582087 +r_4012 triglyceride (1-18:1, 2-16:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn 3.730029896002417e-07 8.169252960607909e-06 2190.130692883492 4.982327538961587e-07 1.2319920430109436e-05 2472.7239094114525 1.1389761588801426e-06 2.7592085931395107e-05 2422.5341080470057 2.0596264043219007e-06 4.38816008123168e-05 2130.561189166932 3.141334961829606e-06 6.625944343768763e-05 2109.276605099641 2.9496861093233665e-06 7.103673727617538e-05 2408.2812422529464 2.7756736655142697e-06 6.754679545343925e-05 2433.5279861123136 5.670823469957928e-06 0.0001106134459619 1950.5711392344167 5.328857904424233e-06 0.000104268855322 1956.68297395426 +r_4013 triglyceride (1-18:1, 2-18:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn 2.8251739300451864e-07 6.442579427681218e-06 2280.4186882675126 4.445806542829546e-07 9.644162025658167e-06 2169.271634460305 7.545341257132916e-07 1.963033381115088e-05 2601.649566557846 2.1375877877579407e-06 4.131854341556252e-05 1932.9518839972625 1.273325960079304e-06 3.596694796201036e-05 2824.645777250179 2.44687038721162e-06 5.425964583265027e-05 2217.512056062885 2.2412679246988184e-06 5.370755082352671e-05 2396.302121297878 2.0388391855658604e-06 5.4878554150210926e-05 2691.6568279994044 3.65936306507964e-06 8.762345062327921e-05 2394.500055472693 +r_4014 triglyceride (1-16:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn 5.103557166760579e-06 2.997362822498944e-05 587.3085623534777 4.448151056002856e-06 3.625414683298597e-05 815.0385716793583 1.9129566028042697e-05 0.0001145912002932 599.0266591790744 2.1726391164956053e-05 0.0001464613007507 674.1170203500524 3.420315607270692e-05 0.0002206261670486 645.0462249145758 3.397025141677983e-05 0.0002393108455099 704.4718114502413 4.370612631245614e-05 0.0002835467933149 648.7575478271783 5.879942372614479e-05 0.0003567831776975 606.7800585244847 4.272663741498778e-05 0.0003218933868383 753.3787031070922 +r_4015 triglyceride (1-16:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn 1.8912779181883991e-06 1.8426405227681044e-05 974.2833166122496 2.285557717210362e-06 2.6188436007835123e-05 1145.8225627222148 6.045331513239192e-06 6.498414532466101e-05 1074.9475886036462 9.763707289321396e-06 0.0001006809168041 1031.1750836103772 1.3725295355211503e-05 0.0001413394895498 1029.7737563526446 1.4897548110548034e-05 0.0001597373617639 1072.2392743999274 2.041107733084013e-05 0.0001990334738658 975.1247846436972 2.303706394348412e-05 0.0002285927517738 992.2824902280418 2.900873257169006e-05 0.0002726825305195 940.0015317652834 +r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn 0.0001684006371481 6.295609636860618e-05 37.38471387920637 0.0002840077720115 9.130871049885044e-05 32.15007457441426 0.0006422411047006 0.0002352711800482 36.63284369783633 0.0009654740252183 0.0003372704387279 34.93314474738967 0.0013330156260951 0.0005103250875213 38.28350377378714 0.0015911474739762 0.0005876702698177 36.93373992224361 0.0017869180444389 0.0006541716020056 36.6089314527599 0.0020731411222368 0.0007952723700351 38.36074454869044 0.0023809833727914 0.0008690391750912 36.49917025974078 +r_4017 triglyceride (1-16:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn 1.821085274063886e-06 1.785431295577997e-05 980.4215766314312 3.1174546458458576e-06 3.033519703533145e-05 973.0758096434348 8.564224254695015e-06 7.639057470401594e-05 891.9730781470099 8.350687100722213e-06 9.317782151349036e-05 1115.8102368059251 1.7348917854847598e-05 0.0001587182535688 914.8596753804848 2.4940221037208924e-05 0.0002070347821744 830.1240869741042 2.373213113876321e-05 0.000211547057566 891.3951146195448 3.269644134732539e-05 0.0002684282994289 820.9709936855768 3.134420645546087e-05 0.0002807132419352 895.5825451640118 +r_4018 triglyceride (1-18:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn 2.007155613474012e-06 1.7691287999307888e-05 881.4108821730849 1.752340635918892e-06 1.6646562232608597e-05 949.9615480799188 6.137090952962864e-06 6.006693409078391e-05 978.752548253905 1.0170339964467589e-05 9.67892782267021e-05 951.6818372331466 1.547425192884318e-05 0.0001407590819897 909.6341628468458 1.3197122575612742e-05 0.0001382038011729 1047.2267752394218 1.3957074904602176e-05 0.0001525778563171 1093.193648096265 2.2406889739701734e-05 0.0001970244481413 879.3029752461914 2.3429706128284848e-05 0.0002328067388704 993.6391758212364 +r_4019 triglyceride (1-18:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn 4.080031146414563e-07 5.708667834985711e-06 1399.1726117096816 4.919882342042651e-07 6.95347716518656e-06 1413.3421658818766 1.7702782664653431e-06 2.173185515927809e-05 1227.5954334947223 2.1177355518627733e-06 3.1087767068692584e-05 1467.9721007350324 3.096306574198932e-06 4.451522640072199e-05 1437.687946395904 4.187328928734929e-06 5.242990418454508e-05 1252.1085655524355 4.813571943790416e-06 5.940607235161975e-05 1234.1369994117265 5.523283125610618e-06 7.357366937374172e-05 1332.0640586500424 6.660402436857968e-06 8.573270357820873e-05 1287.2000512127156 +r_4020 triglyceride (1-18:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn 1.875397227468626e-06 1.840205108564473e-05 981.2348454030432 2.469084990260507e-06 2.6696199316836863e-05 1081.218322663742 5.905852949274237e-06 6.337592138253451e-05 1073.1036130915295 1.030342650587514e-05 9.961811049092528e-05 966.8444806601163 2.014298085986371e-05 0.0001697378488417 842.6649959241656 1.754355171392246e-05 0.0001714876884577 977.4969815357988 2.0426283815250324e-05 0.0001917941611195 938.9576824363812 2.417298466116882e-05 0.0002306186144459 954.0345045449624 2.8323875572584355e-05 0.0002628856837834 928.141641879912 +r_4021 triglyceride (1-18:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn 1.7468437347119072e-07 4.168194503740864e-06 2386.1290056538974 2.362599920285611e-07 7.599133228771253e-06 3216.428293052937 4.138511713443214e-07 1.2151352728082647e-05 2936.164875071189 6.819469122184348e-07 2.5258877898154083e-05 3703.936104935892 4.678921150216225e-07 1.7091921355108652e-05 3652.962041114712 1.2404798879038128e-06 3.8261742934853474e-05 3084.4307358750425 1.7507353593125122e-06 4.982646086241338e-05 2846.030417868494 1.505692478520042e-06 4.777718452577152e-05 3173.103751752292 1.4749349141254825e-06 4.720645939900187e-05 3200.579154165016 +r_4022 triglyceride (1-16:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn 4.932677034724329e-07 8.632377252907283e-06 1750.039013731966 1.2162791820646923e-06 1.731261429186154e-05 1423.407926991938 2.1051682283555973e-06 3.442507882579695e-05 1635.2649808270803 3.279309353279609e-06 5.187824080549944e-05 1581.986791017946 3.2359654446441093e-06 6.031655856839935e-05 1863.9432218978145 7.273597310534867e-06 0.0001033472011686 1420.8540390178107 5.775292346040519e-06 8.766625889448016e-05 1517.9536141505157 7.368352136488125e-06 0.0001172544632966 1591.3254568280815 7.329512729239905e-06 0.000121905664188 1663.2164877995194 +r_4023 triglyceride (1-16:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn 2.669383432802596e-07 5.372308239486251e-06 2012.5652139250165 2.145974086942946e-07 6.218727502131854e-06 2897.857686152567 1.1059326905792186e-06 2.2634080712641896e-05 2046.6056302927057 1.4995982341536407e-06 3.200768130672628e-05 2134.417111046487 1.53157394986433e-06 3.859026904961752e-05 2519.647781488835 1.9188096813843395e-06 5.1494000058334006e-05 2683.642914558534 3.0039061826334463e-06 6.199156423339206e-05 2063.6984134786017 3.5782646507375857e-06 7.462367622513732e-05 2085.4711294133926 4.484814789496122e-06 9.250130082361404e-05 2062.544501063036 +r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn 9.77149784035213e-07 1.063119470083264e-05 1087.980049172229 9.67701207566406e-07 1.3695722409681668e-05 1415.2842119649658 2.6963698996636337e-06 3.524646267216345e-05 1307.182025602658 4.906868438965848e-06 5.889794477977515e-05 1200.316362918184 6.347687357266663e-06 7.878710041094691e-05 1241.1937761987213 1.1210203086159708e-05 0.0001103715924487 984.5637193229888 6.854667978694411e-06 9.145181841241668e-05 1334.1538743622016 1.0652980429940212e-05 0.0001306185276487 1226.1219149680403 8.826567160837997e-06 0.0001212850660506 1374.0910122884238 +r_4025 triglyceride (1-16:1, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn 2.2104120620251261e-07 5.74769662274018e-06 2600.282871002016 2.4697302620268737e-07 7.802128522083735e-06 3159.101478426488 5.152524067774269e-07 1.7342878144868793e-05 3365.8994925103534 9.356388080132078e-07 2.7552824788212588e-05 2944.814233039342 2.024045301928464e-06 4.9515293715318325e-05 2446.353037065983 1.8322769379060465e-06 4.7951962897231325e-05 2617.069609140612 1.3046719368180484e-06 3.740542022301709e-05 2867.036468512138 1.193813292358926e-06 4.026359447938018e-05 3372.687734094581 2.396044154582492e-06 6.467069974129459e-05 2699.0612680325744 +r_4026 triglyceride (1-18:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn 5.821747945364431e-07 6.263352257048843e-06 1075.854247870013 7.351225852669e-07 8.94367735107466e-06 1216.6239386901016 1.4755726255873092e-06 1.7542341890549385e-05 1188.8497784761466 3.1570960442430856e-06 3.3896740465976656e-05 1073.6683328905 3.368465472483329e-06 3.893219046533422e-05 1155.7841629480113 4.2389104542676414e-06 4.895918333686384e-05 1154.9945172248877 5.393452739364729e-06 6.073439284173333e-05 1126.0762961443315 5.957760921743088e-06 6.617939299534971e-05 1110.8098136973802 6.85524312560776e-06 7.773862150907993e-05 1134.0023991080243 +r_4027 triglyceride (1-18:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn 3.130611335704522e-07 4.7050015542667554e-06 1502.901845593659 3.044460790420711e-07 5.569909121822898e-06 1829.5223703811264 1.2329665754289354e-06 1.794713574033116e-05 1455.606023552386 1.0643432615006518e-06 2.0040333368361485e-05 1882.8825336016105 2.2051333350650765e-06 3.2698369182681344e-05 1482.8295714697167 1.8484587885952424e-06 3.3718109903512524e-05 1824.1201865872808 2.4312764677167866e-06 4.343087062535714e-05 1786.3402703084237 3.955306131512936e-06 6.051184187404922e-05 1529.890224979955 4.31809270688063e-06 6.683400060582356e-05 1547.766691051525 +r_4028 triglyceride (1-18:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn 3.201212783714164e-07 6.934994597986132e-06 2166.364770647923 2.5215726073445535e-07 7.957130332362489e-06 3155.622134054698 3.5243717835145777e-07 1.231448821097819e-05 3494.094541495257 1.5304631554368715e-06 3.5474014375622233e-05 2317.8613774270284 8.340139641242148e-07 3.0951475904505246e-05 3711.1460042526887 1.2094685508960307e-06 3.879459921449333e-05 3207.5740361956896 1.9675907968945647e-06 4.872246954503758e-05 2476.250123853797 1.742861210716583e-06 5.224011555772603e-05 2997.3766836113896 2.0160345916799977e-06 6.0063546199745735e-05 2979.291449046701 +r_4029 triglyceride (1-18:1, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn 1.8311063986125722e-07 3.772254737338779e-06 2060.095874383386 1.2181471753656053e-07 4.617377875884725e-06 3790.4926180195766 8.0543485565817e-07 1.7230126246757507e-05 2139.232754296152 1.0897021318234284e-06 2.3926428196240985e-05 2195.685178316045 1.7503490298540136e-06 3.729724435623343e-05 2130.8461181221764 1.930635809389928e-06 3.939023222014479e-05 2040.2725376046933 2.3547584800348944e-06 5.0172398991576296e-05 2130.6813168725826 2.318681564641281e-06 5.645165697995349e-05 2434.6446636231835 3.120865513134135e-06 6.466403525901355e-05 2071.9904458194537 +r_4030 triglyceride (1-16:0, 2-16:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn 1.78736275913203e-07 5.422825706539733e-06 3033.9815903813155 3.03409523346072e-07 8.900893003845e-06 2933.623475520428 6.216879300224465e-07 2.037035136323952e-05 3276.620049950789 5.285530844132592e-07 2.204114448008361e-05 4170.090976680466 1.004081937660805e-06 3.708868278326818e-05 3693.790455953539 1.799910180484972e-06 5.042631854507274e-05 2801.601940574932 1.77635172955641e-06 5.794418168467235e-05 3261.97682140024 2.21712617341097e-06 6.741957366266318e-05 3040.8541683913527 1.8033367595027928e-06 6.616703996224577e-05 3669.144967714682 +r_4031 triglyceride (1-16:0, 2-18:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn 1.8710880200832637e-07 5.339487939349779e-06 2853.680790020863 2.3758075253991539e-07 7.161950787197015e-06 3014.533252643752 3.1598948351800654e-07 7.5999239935882525e-06 2405.119280862135 8.251520699801255e-07 2.89180369895054e-05 3504.570616929061 5.838668684621324e-07 1.8893057692761183e-05 3235.850279109736 6.963514723335459e-07 2.087643839238482e-05 2997.9743307536514 8.759513252712679e-07 2.947624342094354e-05 3365.0549488940187 1.6472249244241103e-06 4.387038845121708e-05 2663.290714020412 6.807782680569948e-07 2.5264432959803115e-05 3711.1103784070815 +r_4032 triglyceride (1-16:1, 2-16:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn 7.132371285411484e-08 3.166419576330389e-06 4439.504688723888 1.2947711254239633e-07 2.565507974012118e-06 1981.437432173243 3.3788960678022546e-07 1.2159743139832625e-05 3598.7325137649827 3.9870216083407693e-07 1.6429390004427887e-05 4120.717572751031 8.271045554310219e-07 2.6908012636533696e-05 3253.2782536195023 1.1152714809026271e-06 3.396421559283364e-05 3045.376500199327 9.2107430625719e-07 3.330207101514446e-05 3615.568341111188 7.043801237267518e-07 3.511490032352849e-05 4985.220215718426 1.833388866110017e-06 5.807687572947412e-05 3167.7336326743616 +r_4033 triglyceride (1-16:1, 2-18:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn 9.418236920343763e-10 5.6107064146055626e-08 5957.278906932374 9.611596129838468e-08 4.526488546421505e-06 4709.403605057194 2.8098313573122015e-07 9.924462998498028e-06 3532.0493426308203 1.2294549136841476e-07 8.685626698368278e-06 7064.615873014156 1.1532155492637349e-07 4.837302428470164e-06 4194.6212323953805 1.7194601629731825e-07 7.431113608998864e-06 4321.771314637176 2.8033972290004145e-08 1.981127669808717e-06 7066.88174374458 2.737840650000574e-07 1.935880738807774e-05 7070.830578862828 1.02018358723757e-06 4.463023668794925e-05 4374.726004835855 +r_4034 triglyceride (1-18:0, 2-16:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn 3.6147878469950265e-08 2.555633919641968e-06 7069.941661352178 6.071014605987449e-08 4.2920389783304855e-06 7069.722701865228 2.014447770455342e-07 1.0699720453558223e-05 5311.490628093911 2.299999999938098e-12 1.4508245856652968e-10 6307.932981323238 8.504327911349573e-07 3.4716226921974095e-05 4082.1834816179953 3.399386212562784e-07 2.4037673681167265e-05 7071.180553811026 -2.400000000000001e-12 1.2488938894835554e-10 -5203.724539514813 5.357356137132694e-07 3.22052917410959e-05 6011.415130287095 1.4848200117271943e-06 6.063866308474642e-05 4083.9066422744 +r_4035 triglyceride (1-18:0, 2-18:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn 7.148923879301333e-09 2.5514413070195435e-07 3568.986535731441 5.960198964322501e-08 3.2030684533011385e-06 5374.0965234123405 1.1043478975569161e-07 2.9084924355949864e-06 2633.67408226092 8.656962802215717e-09 6.10916455518692e-07 7056.937513492957 1.2189689542860698e-08 8.622991130312357e-07 7074.003894843 1.295519235223291e-07 6.42767303793939e-06 4961.464764999448 3.942022218311064e-07 1.978388360146807e-05 5018.714382067678 4.073205564343889e-07 2.2645559551802487e-05 5559.640728677595 1.5192195374158229e-07 5.172774964905652e-06 3404.8897065295064 +r_4036 triglyceride (1-18:1, 2-16:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn 3.62784566520837e-08 2.565177168663648e-06 7070.80015355701 2.9711074685268366e-08 1.258977026906002e-06 4237.399825628793 8.151462574939628e-08 3.0216407975880536e-06 3706.86949711038 4.259295303213463e-07 1.7928139678611073e-05 4209.179782647385 1.0458063603173841e-07 7.375742425417932e-06 7052.68461283743 5.167829577048019e-07 2.1054961808205097e-05 4074.236871455069 3.09660068092765e-07 1.2109931625195673e-05 3910.717871949797 6.179198751354924e-08 4.369747918196103e-06 7071.706371700604 2.0064016060696454e-07 8.756618184562263e-06 4364.339700522702 +r_4037 triglyceride (1-18:1, 2-18:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn 3.8287866894294833e-08 9.628390888660832e-07 2514.7368264841966 6.69199715605576e-08 1.9342894586111325e-06 2890.451704482188 3.07765531806052e-07 1.184097587551154e-05 3847.401561190256 3.190738439114669e-07 1.1516425249289273e-05 3609.329147169056 4.762325472404329e-07 1.7327177343460198e-05 3638.3857936346217 3.689969542256718e-07 1.7599209362512036e-05 4769.472799428226 6.8093685723685e-07 2.408734993133858e-05 3537.3837787371067 7.38849083591154e-07 2.85684210708162e-05 3866.611153114008 1.1796418549246886e-06 4.110632107768351e-05 3484.6441660301925 +r_4038 triglyceride transport, ER membrane-cytoplasm 0.0001557664716836 1.1508900176719804e-06 0.7388560614053413 0.0002537682474343 1.5656007316987176e-06 0.6169411451304117 0.0005893041225315 1.6603973813508876e-06 0.2817556025602244 0.000876016161504 2.3716749002322773e-06 0.2707341490321566 0.0012351964756453 5.200739786935824e-06 0.4210455493907094 0.0014639971018673 4.264073337653582e-06 0.2912624165863826 0.0016390078670343 7.743772977107996e-06 0.4724671023769974 0.0019248569483904 1.1299631705231317e-05 0.5870374790542104 0.0021825478510572 1.0988327291130016e-05 0.5034632934076166 +r_4039 succinyl-CoA:acetate CoA transferase -0.0327889595994926 0.0088770944325655 -27.07342514369652 -0.0529110247140541 0.0159812145488056 -30.203940738574943 -0.1184212154300742 0.0194949152054645 -16.462350208671868 -0.1757333028112084 0.0301127650130873 -17.135491413052055 -0.2503996087734349 0.0482753704067753 -19.279331402812065 -0.2942845583909854 0.0510504484016411 -17.34730788484514 -0.3337398209429811 0.0661425296515183 -19.818590860579 -0.3953780279862903 0.0973910325296347 -24.63238360150144 -0.4424328436206308 0.1013403105442746 -22.905241327691773 +r_4040 heme a transport 1.3958301013697196e-05 0.0001439642894916 1031.3883426814464 8.005891317926721e-06 0.0001060046000509 1324.082426820108 1.442112067883581e-05 0.0001678546714673 1163.9502588293217 1.3929719867077416e-05 0.0002030935302796 1457.987182927427 4.5321993977749794e-05 0.000513016162131 1131.9364332975897 3.8587116727232353e-05 0.0004661301435597 1207.9942299259296 4.060587165422495e-05 0.0005824694663705 1434.4464055113838 9.34688555710928e-05 0.0011187945380192 1196.9704038670634 9.266253253933534e-05 0.0010814233637298 1167.055695645665 +r_4041 biomass pseudoreaction 0.0227160857623202 0.0001678391766621 0.7388560618157782 0.0370081007181382 0.0002283182003614 0.6169411451303478 0.0859407216653628 0.0002421427981728 0.281755602560196 0.1277531553432387 0.0003458714179802 0.2707341490321219 0.1801339452021157 0.0007584459592154 0.4210455493907324 0.2135009117363308 0.0006218479149572 0.2912624165864284 0.2390234745059068 0.0011293072839988 0.4724671023769677 0.2807100594115241 0.0016478732562208 0.5870374790541678 0.3182902175930254 0.0016024744120882 0.5034632934076538 +r_4042 raffinose invertase -1.260000000000001e-11 1.2978678253884258e-10 -1030.053829673353 -4.599999999999987e-11 2.2515358941790342e-10 -489.4643248215306 -1.3000000000000008e-11 1.6981391978713034e-10 -1306.2609214394631 -3.464000000000097e-10 4.95637136657705e-10 -143.08231427762453 -7.872000000000323e-10 4.1563290310324e-10 -52.798895211283394 -5.424000000000242e-10 5.081868660032027e-10 -93.69226880589598 -2e-12 1.6613705277289338e-10 -8306.85263864467 -1.4519999999999938e-10 3.900607510092381e-10 -268.636880860358 -1.759999999999999e-11 1.8573405564916507e-10 -1055.307134370257 +r_4043 raffinose exchange 1.260000000000001e-11 1.2978678253884258e-10 1030.053829673353 4.599999999999987e-11 2.2515358941790342e-10 489.4643248215306 1.3000000000000008e-11 1.6981391978713034e-10 1306.2609214394631 3.464000000000097e-10 4.95637136657705e-10 143.08231427762453 7.872000000000323e-10 4.1563290310324e-10 52.798895211283394 5.424000000000242e-10 5.081868660032027e-10 93.69226880589598 2e-12 1.6613705277289338e-10 8306.85263864467 1.4519999999999938e-10 3.900607510092381e-10 268.636880860358 1.759999999999999e-11 1.8573405564916507e-10 1055.307134370257 +r_4044 melibiose exchange -1.260000000000001e-11 1.2978678253884258e-10 -1030.053829673353 -4.599999999999987e-11 2.2515358941790342e-10 -489.4643248215306 -1.3000000000000008e-11 1.6981391978713034e-10 -1306.2609214394631 -3.464000000000097e-10 4.95637136657705e-10 -143.08231427762453 -7.872000000000323e-10 4.1563290310324e-10 -52.798895211283394 -5.424000000000242e-10 5.081868660032027e-10 -93.69226880589598 -2e-12 1.6613705277289338e-10 -8306.85263864467 -1.4519999999999938e-10 3.900607510092381e-10 -268.636880860358 -1.759999999999999e-11 1.8573405564916507e-10 -1055.307134370257 +r_4045 uridine hydrolase 0.000191936974316 0.0037596696263484 1958.8042584006096 0.0003225065107568 0.0065758844713615 2038.992780620078 4.541614600084613e-05 0.0022705872353002 4999.515448224018 0.0003350196480227 0.0074845398882422 2234.05998197853 0.0006697383729509 0.0149623151203331 2234.0537327147795 0.000547212012413 0.0122249271140642 2234.038514643854 0.0011070045812317 0.0235778053245376 2129.8742321647646 0.001324187883627 0.0313686147484929 2368.8945606850616 0.000880517997255 0.0254056544230061 2885.307796343223 +r_4046 non-growth associated maintenance reaction 1.402644910835488 0.0014762718347648 0.1052491491866946 2.5532822293319803 0.0019004161462687 0.0744303204885388 2.15732013678463 0.0022705472985644 0.1052485099382878 3.1869246918126346 0.0041076989049531 0.1288922488663142 6.362718403456992 0.0082007877980367 0.1288881147652407 5.198535744544199 0.0038692723733668 0.0744300426793765 9.563804267398806 0.0100657469522277 0.1052483579838616 14.51548224843692 0.0152773004249625 0.105248314616675 13.94432242255514 0.0179725709015078 0.1288880904850346 +r_4047 protein pseudoreaction 0.0227160857625298 0.000167839176617 0.738856061610493 0.0370081007181382 0.0002283182003614 0.6169411451303478 0.0859407216651628 0.0002421427982147 0.2817556026096016 0.1277531553415437 0.0003458714183387 0.2707341493164058 0.1801339451905616 0.0007584459617127 0.4210455508040877 0.2135009117308991 0.0006218479161883 0.29126241717042 0.2390234745049951 0.0011293072842035 0.4724671024644478 0.2807100594115241 0.0016478732562208 0.5870374790541678 0.3182902175872396 0.0016024744133529 0.5034632938141678 +r_4048 carbohydrate pseudoreaction 0.0227160857623202 0.0001678391766621 0.7388560618157782 0.0370081007181382 0.0002283182003614 0.616941145130348 0.0859407216653628 0.0002421427981728 0.2817556025601961 0.1277531553432387 0.0003458714179802 0.2707341490321219 0.1801339452021157 0.0007584459592154 0.4210455493907324 0.2135009117363308 0.0006218479149572 0.2912624165864282 0.2390234745059068 0.0011293072839988 0.4724671023769677 0.2807100594115241 0.0016478732562208 0.587037479054168 0.3182902175930254 0.0016024744120882 0.5034632934076538 +r_4049 RNA pseudoreaction 0.0227160857623202 0.0001678391766621 0.7388560618157782 0.0370081007181382 0.0002283182003614 0.6169411451303478 0.0859407216653628 0.0002421427981728 0.2817556025601961 0.1277531553432387 0.0003458714179802 0.2707341490321219 0.1801339452021157 0.0007584459592154 0.4210455493907324 0.2135009117363308 0.0006218479149572 0.2912624165864283 0.2390234745059068 0.0011293072839988 0.4724671023769677 0.2807100594115241 0.0016478732562208 0.5870374790541679 0.3182902175930254 0.0016024744120882 0.5034632934076538 +r_4050 DNA pseudoreaction 0.0227160857623202 0.0001678391766621 0.7388560618157782 0.0370081007181382 0.0002283182003614 0.616941145130348 0.0859407216653628 0.0002421427981728 0.2817556025601961 0.1277531553432387 0.0003458714179802 0.2707341490321219 0.1801339452021157 0.0007584459592154 0.4210455493907324 0.2135009117363308 0.0006218479149572 0.2912624165864284 0.2390234745059068 0.0011293072839988 0.4724671023769677 0.2807100594115241 0.0016478732562208 0.5870374790541679 0.3182902175930254 0.0016024744120882 0.5034632934076538 +r_4051 ceramide transport 3.7870391316514676e-09 5.256347571214521e-09 138.79834320387155 2.268978125084485e-09 4.754611609186447e-09 209.54858738487872 2.965816874345809e-09 5.112679911269617e-09 172.38690478478568 2.286077261796244e-09 4.52685268906212e-09 198.0183594278536 3.386788451422809e-09 4.937758963373462e-09 145.7947266029882 3.149790958002098e-09 4.843469007235414e-09 153.77112550693238 3.514608986166934e-09 4.909144700556377e-09 139.67826065084802 3.725485750472289e-09 4.947372606293786e-09 132.79805474136077 3.603656242073341e-09 5.434392441008494e-09 150.80218744399022 +r_4052 inositol phosphomannosylinositol phosphoceramide transport -1.8275931253059856e-10 1.9434386303399964e-09 -1063.3869231777803 1.3419123305067312e-11 1.451961198814013e-09 10820.089850919883 5.3609831770224906e-11 1.579309396154352e-09 2945.932385916395 3.255728631909923e-11 1.731596309455828e-09 5318.613758174353 -1.7948032828941543e-11 1.4474461205586115e-09 -8064.650507127317 -7.322851230172264e-11 1.864260688163527e-09 -2545.8125934366026 2.124204283638938e-12 1.8480360644151286e-09 86998.980213395 3.131125603621287e-11 1.63289359945067e-09 5215.037038316686 3.009387771695446e-11 2.135209724503844e-09 7095.1631577239295 +r_4053 inositol-P-ceramide transport -4.9670079493349004e-09 7.0790028220302815e-09 -142.52046492049976 -3.0531276314386406e-09 6.233830135794364e-09 -204.1784978657106 -4.092670599338e-09 6.893217367661331e-09 -168.42834526620163 -3.112693284386626e-09 6.016981003928153e-09 -193.3046546574162 -4.614492104661494e-09 6.675417175197679e-09 -144.66201314884185 -4.2553806904600595e-09 6.517132531464964e-09 -153.15039958881758 -4.787590420312409e-09 6.702896772885658e-09 -140.00564343280368 -5.0870848092165755e-09 6.786505891069146e-09 -133.40658049918156 -4.973429488073933e-09 7.353941794817718e-09 -147.86460353870805 +r_4054 mannosylinositol phosphorylceramide transport -7.546948749328578e-11 1.6461690877034852e-09 -2181.237931223448 3.900846717699812e-11 1.6364883802192759e-09 4195.213241253053 1.070279528388309e-10 1.4915138864849302e-09 1393.5741522879923 9.997482795283636e-11 1.7503336718357455e-09 1750.774377587801 7.273672157334352e-11 1.4266071442005702e-09 1961.330004077874 4.05515460179602e-12 1.2457997263450092e-09 30721.38669616313 6.836497388471541e-11 1.777275441302951e-09 2599.687150177209 -1.2545150589166246e-11 1.3159580045521123e-09 -10489.774476589771 8.516380897096409e-11 1.6741603021118244e-09 1965.81191276052 +r_4055 long-chain base transport 6.570343388630857e-11 1.7253260977911092e-09 2625.929872670836 8.253880743983907e-10 1.272135888321357e-09 154.12578976847854 6.95558932422234e-10 1.3907105046210943e-09 199.94143411803293 8.336415788805103e-10 1.2754376863568275e-09 152.99592998583404 6.714835598503171e-10 1.401907922939449e-09 208.77769863076816 -7.501317488412753e-11 1.8955983999301606e-09 -2527.0206238547853 7.726251448272807e-10 1.4133271179947975e-09 182.92533286769284 5.217597722630926e-10 1.7289550683130803e-09 331.3699446037917 7.210027517972175e-10 1.4423122395931167e-09 200.04254297198125 +r_4056 long-chain base phosphate transport 2.0545670533147863e-10 2.0398561474444367e-09 992.8398998481867 9.47687430354344e-10 1.550563472565138e-09 163.61549419151592 9.029477178050223e-10 1.695335668812606e-09 187.75568456319945 8.849286213267718e-10 1.4488289544391162e-09 163.72269124563857 8.530753525873923e-10 1.438766227810423e-09 168.65640572624915 8.722921871903213e-11 2.059094250510326e-09 2360.555649526942 1.0300583000254806e-09 1.6512324277691522e-09 160.30475437441802 8.099515919847217e-10 1.74084728274823e-09 214.93226261614257 9.380931589656187e-10 1.6295712723262832e-09 173.7110282440518 +r_4057 phosphatidate transport 3.1630632846429877e-10 1.9323226083766387e-09 610.9022913826203 2.0279243046159943e-10 9.601041218045375e-10 473.4417944590599 2.6490639043959967e-10 1.0931453818610627e-09 412.65345847151485 2.4676003287239937e-10 1.054661524977473e-09 427.4037058192656 2.762180862187993e-10 1.1244845938695275e-09 407.10027690902 2.921330706599994e-10 1.1350231817238874e-09 388.52950785735936 2.427682423975994e-10 1.040631721063515e-09 428.652327333324 2.69219789572649e-10 1.1113997148974335e-09 412.822443945014 2.31720003440019e-10 1.014010845721296e-09 437.601773980542 +r_4058 diglyceride transport 2.8008686805139075e-10 1.533656773972121e-09 547.5646840003665 1.6963862886984406e-10 8.214535901235911e-10 484.23734357924735 2.3735298010399977e-10 9.655955273019223e-10 406.8183710517695 2.0752529890645064e-10 8.958472962137074e-10 431.6810051277375 2.3622246185599936e-10 9.64348769528361e-10 408.23754098212106 2.7352350071981824e-10 1.233981823218544e-09 451.1428889916718 1.932727152475156e-10 8.564825899314987e-10 443.1471813466481 2.3152283132714267e-10 9.640272750096195e-10 416.3854033244113 1.9920366299199927e-10 8.678770831877609e-10 435.6732552767454 +r_4059 sn-2-acyl-1-lysophosphatidylinositol transport -3.294413554205657e-10 1.1971224315533372e-09 -363.37952471847007 -3.4792748625653287e-10 1.0337031555092084e-09 -297.1030448416602 -3.496958935884069e-10 5.793266528237e-10 -165.66584379328435 -2.861212684252044e-10 5.64359269364362e-10 -197.2447810225938 -3.7926940869880874e-10 6.041059336552828e-10 -159.28148165912972 -2.7427754365099124e-10 5.657072426752655e-10 -206.253576266203 -3.625091224724079e-10 5.83236671661578e-10 -160.88882610284395 -3.059278080866881e-10 5.478467230285138e-10 -179.07712491218683 -2.5414513389360264e-10 5.459798598922001e-10 -214.82994835571924 +r_4060 phosphatidylglycerol transport -1.6584535127654614e-10 3.975421734556629e-09 -2397.0655215578736 2.452120803397825e-09 4.377579185258131e-09 178.52216657483837 2.461773494701266e-09 3.896416394074685e-09 158.27680338834386 2.2705999236070063e-09 3.948087618852522e-09 173.87861145439967 1.731396918062318e-09 3.6233526770046796e-09 209.27336991333743 5.970184595193441e-11 4.060830552613035e-09 6801.850910744677 2.3219218238262236e-09 4.089009332674128e-09 176.10452215552957 1.6916292125530023e-09 4.306993160799382e-09 254.60621800798057 2.087005693885227e-09 3.3808516713201676e-09 161.9953257063847 +r_4061 cardiolipin transport 6.3805403648645705e-12 2.352589777252828e-10 3687.132504023839 4.339999999999988e-11 2.0377621291256706e-10 469.5304444990039 1.954068181752877e-10 7.801106688856363e-10 399.2238736449032 6.478071239313985e-11 4.767285632702387e-10 735.9112699735042 1.0367516404512048e-10 5.919135005181674e-10 570.9308550122579 2.4189717169121223e-11 6.524179645658173e-10 2697.08802299948 1.0019219936278243e-10 9.354348594621195e-10 933.6404085462144 1.6964229631113275e-10 6.132124370341984e-10 361.4737894785008 1.3487344896449127e-11 9.414371841207903e-10 6980.152071062159 +r_4062 lipid backbone exchange 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4063 lipid backbone pseudoreaction 0.0227160857627394 0.000167839176572 0.738856061405202 0.0370081007181382 0.0002283182003614 0.6169411451303481 0.0859407216653628 0.0002421427981728 0.2817556025601963 0.1277531553432387 0.0003458714179802 0.2707341490321222 0.1801339452021157 0.0007584459592154 0.4210455493907327 0.2135009117363308 0.0006218479149572 0.2912624165864286 0.2390234745059068 0.0011293072839988 0.472467102376968 0.2807100594115241 0.0016478732562208 0.5870374790541681 0.3182902175930254 0.0016024744120882 0.5034632934076542 +r_4064 lipid chain exchange 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4065 lipid chain pseudoreaction 0.0227160857625298 0.000167839176617 0.738856061610493 0.0370081007181382 0.0002283182003614 0.6169411451303478 0.0859407216653628 0.0002421427981728 0.2817556025601961 0.1277531553434875 0.0003458714179275 0.2707341489904118 0.1801339452021157 0.0007584459592154 0.4210455493907324 0.2135009117363308 0.0006218479149572 0.2912624165864282 0.2390234745059068 0.0011293072839988 0.4724671023769679 0.2807100594115241 0.0016478732562208 0.587037479054168 0.3182902175930254 0.0016024744120882 0.5034632934076538 +r_4066 ceramide-1 (C24) [Golgi] SLIME rxn 4.4849623927077665e-10 3.145152757426381e-09 701.2662497549986 3.933146671156808e-10 3.337977154681649e-09 848.6785349654633 -1.4838622212417924e-10 3.871243300955728e-09 -2608.8967328220137 1.2962555334865126e-10 3.3535565640477063e-09 2587.110702646501 4.3029661147112567e-10 3.2917337935184552e-09 764.9918000200986 3.96844727085376e-10 3.123417436146321e-09 787.0628543022972 2.9836411731299037e-10 2.998243905082922e-09 1004.8942654648044 4.837146610103744e-10 3.3803794805982902e-09 698.8375075374839 3.9291956610076605e-10 3.22304299032709e-09 820.280604071655 +r_4067 ceramide-1 (C26) [Golgi] SLIME rxn 7.223085801008184e-10 3.727319741854749e-09 516.028722977996 -3.8831900829250565e-10 3.8824961246553405e-09 -999.82129170736 1.9788000793775016e-10 3.524676576262678e-09 1781.219140324415 2.605413700760193e-12 3.105036259346777e-09 119176.32345453648 6.675046402309972e-11 3.269067389526449e-09 4897.445189886851 4.654097888211796e-10 3.6754425470776316e-09 789.7217968678813 3.2181227350508725e-10 3.170170649358702e-09 985.0993608261452 4.4615913351297887e-10 3.264459826391797e-09 731.6806003024107 1.8980724447948638e-10 4.159943435528829e-09 2191.667365983188 +r_4068 ceramide-2 (C24) [Golgi] SLIME rxn 4.6169983245580384e-10 2.872432475267153e-09 622.1428454908777 3.3392414163853194e-10 2.9726007903705263e-09 890.2024201617396 3.9907603585391054e-10 3.2998149269475003e-09 826.8637127976938 2.068839887514652e-10 3.1030266417966004e-09 1499.887284909391 4.4261249718459117e-10 2.825995462222189e-09 638.4807207654623 3.5168566578140234e-10 3.0590895738358437e-09 869.8362974330846 3.4654362406374393e-10 2.716497628978344e-09 783.883309444085 3.08868959071337e-10 3.0991750794941402e-09 1003.3948017347864 4.5300981463802015e-10 2.9205221777840083e-09 644.6929146816977 +r_4069 ceramide-2 (C26) [Golgi] SLIME rxn 5.371659621915416e-10 3.777346014259739e-09 703.199063255765 3.7620814279792537e-11 3.814390250850639e-09 10139.042239974808 5.78405265739551e-10 3.914076747516416e-09 676.7014374448794 -9.27725662691218e-12 3.324571877995645e-09 -35835.72182698354 3.5516388256974024e-10 3.7455054081432875e-09 1054.585106189061 3.360509450558756e-10 3.7408108481911375e-09 1113.1677810247331 2.9337263619743957e-10 3.178992149111928e-09 1083.6021349218363 2.9317502199310736e-10 3.266808010814918e-09 1114.2859267498309 2.0581552047463649e-10 3.2472850414848662e-09 1577.7649003322092 +r_4070 ceramide-2' (C24) [Golgi] SLIME rxn 6.591306375685898e-10 2.7095004905362353e-09 411.0718476888099 5.186483920368464e-10 3.108681320794718e-09 599.3812703412119 3.601044987818426e-10 3.012505125524491e-09 836.564146161783 4.2826889822303155e-10 2.8826960579943912e-09 673.1042272635816 5.508396700369972e-10 2.6248439023931462e-09 476.5168605625023 7.031102030856553e-10 2.7181119990982367e-09 386.5840642291328 6.658669784946536e-10 2.4721454324714123e-09 371.2671618076434 7.700422430569251e-10 2.002160954281358e-09 260.00663889985447 7.32201057461085e-10 2.416354692988535e-09 330.01245605507194 +r_4071 ceramide-2' (C26) [Golgi] SLIME rxn 6.916708768990201e-10 3.118722790684233e-09 450.89693593381526 5.948377933708454e-10 3.299515677029013e-09 554.6916678463239 6.01823481059554e-10 2.985320365250625e-09 496.0458438734811 5.562304780561867e-10 3.031557556203578e-09 545.0182389857017 7.094525742658684e-10 2.748652654215073e-09 387.43289599862834 5.812681890651403e-10 2.957091738872901e-09 508.731046099189 7.63498171550694e-10 2.6496460652118397e-09 347.04026334867393 8.18018155839166e-10 2.610823101487933e-09 319.1644443159838 7.695008863165686e-10 2.426879323157046e-09 315.3835643743029 +r_4072 ceramide-3 (C24) [Golgi] SLIME rxn 5.519051712910676e-10 3.024262179321201e-09 547.9677192091834 4.282513279852277e-10 2.994479488509841e-09 699.2341395875682 5.836980611723774e-10 2.4296682409189803e-09 416.25429353644057 4.624660989917153e-10 3.128881786340696e-09 676.5645726600052 5.5198817165781e-10 2.683435346005437e-09 486.1400087516656 4.690830371136273e-10 2.495651273812428e-09 532.027610541777 6.256283585731362e-10 2.281849300089504e-09 364.72919886395385 6.291749895676501e-10 2.13444424728186e-09 339.24492910129584 6.307411224636237e-10 2.673152647210377e-09 423.81137871100873 +r_4073 ceramide-3 (C26) [Golgi] SLIME rxn 7.17505144816986e-10 3.277104973483026e-09 456.7360941110626 6.439874961713944e-10 3.952321456443207e-09 613.726427910537 6.06423679303227e-10 3.197991197263006e-09 527.35262596234 5.351354933970191e-10 3.177509162341662e-09 593.7765671589 5.400689496985931e-10 3.2865986777722187e-09 608.5516820780816 5.583042158673075e-10 3.1308075912125964e-09 560.7709027145688 7.275168763667913e-10 3.0028805191308996e-09 412.7575066199482 7.07836452997329e-10 2.5624492233673235e-09 362.0114805498711 6.35736347271577e-10 2.958135911214267e-09 465.3086022074801 +r_4074 ceramide-4 (C24) [Golgi] SLIME rxn 4.4846125302800874e-10 3.6288491505800555e-09 809.1778556292389 1.9581771304435063e-10 3.3655086933579877e-09 1718.6947192033315 4.866110040916619e-10 3.5381456648648782e-09 727.0993946118006 3.77033716731106e-10 3.280289850186245e-09 870.0255984070761 5.460620118747017e-10 3.298969578768854e-09 604.1382676379671 4.367390265599747e-10 3.411341666263099e-09 781.0938475393245 5.540025489986774e-10 3.096068203956596e-09 558.8545051918138 4.719580254338824e-10 2.606612446249692e-09 552.2975149862896 4.71013130071506e-10 2.9023325023076704e-09 616.1892985588443 +r_4075 ceramide-4 (C26) [Golgi] SLIME rxn 2.695603138109845e-10 3.778517118354374e-09 1401.7334617750396 5.189997631211545e-10 4.172404140593667e-09 803.9318005660949 5.86602755940309e-10 3.594712695593378e-09 612.8018764301825 5.947924138862942e-10 3.7688085645313175e-09 633.6342691236465 7.020550532496445e-10 3.74691511729191e-09 533.7067370925311 2.838780806982434e-10 3.841853281831447e-09 1353.3462225691376 4.873508957281843e-10 3.4581034478251632e-09 709.5715793562202 4.766443320122353e-10 3.365410663429504e-09 706.0632923550874 7.324335634566087e-10 4.155606395644907e-09 567.3697387696375 +r_4076 phytosphingosine [endoplasmic reticulum] SLIME rxn 3.183781131141688e-10 3.86744972879273e-09 1214.734797867805 1.4012650941117183e-09 2.949871855517226e-09 210.51490313381365 1.094454749410624e-09 3.139546067906629e-09 286.85937628735303 1.4546170458102847e-09 3.200975890021322e-09 220.0562614910264 1.1960577141995183e-09 3.250794368377632e-09 271.79243357443505 1.2657124747686247e-10 4.345140265785677e-09 3432.959975036968 1.3802469360558447e-09 3.2694254611669943e-09 236.8725027211155 1.1227514473762883e-09 3.254042020362709e-09 289.8274616315968 1.2598715571287515e-09 3.2846208089925472e-09 260.71076772922794 +r_4077 phytosphingosine 1-phosphate [endoplasmic reticulum] SLIME rxn 4.284178840539185e-10 3.5064167731232606e-09 818.4571428119842 1.3395025974691123e-09 2.8936384046800806e-09 216.02335151476296 1.2804821508065631e-09 3.2548927464421198e-09 254.1927464113338 1.261883233810019e-09 2.8031957816289484e-09 222.14383284618395 1.2089569817367084e-09 2.8692692927427794e-09 237.33427541987265 2.2444954436648708e-10 3.7087234709637286e-09 1652.3640007520032 1.4274290853840695e-09 3.209461993516269e-09 224.8421323608324 1.2560750206316523e-09 3.273046523598791e-09 260.5773118513931 1.3307041565437295e-09 3.137954322763779e-09 235.81156693115503 +r_4078 sphinganine [endoplasmic reticulum] SLIME rxn -1.1696911029642118e-10 4.05360437391363e-09 -3465.5340744586774 1.257660046758082e-09 3.0391634238609197e-09 241.65222006496 1.150517182757792e-09 3.531852811506443e-09 306.97957965656667 1.228946640426317e-09 2.873305630887061e-09 233.80230974799048 9.642967934894402e-10 3.2700116361651723e-09 339.10842162320046 -3.8080360518191847e-10 4.292641434902463e-09 -1127.258612179307 1.105309042264407e-09 3.255304832826826e-09 294.5153534759654 5.463156758330723e-10 4.415786762243069e-09 808.2848355960992 1.06100904845862e-09 3.454692114321861e-09 325.6043969974302 +r_4079 sphinganine 1-phosphate [endoplasmic reticulum] SLIME rxn 9.241834428575932e-11 3.921785893320453e-09 4243.514557233587 1.0913571222280803e-09 3.0500110426524303e-09 279.46956871694056 1.0354297703586771e-09 2.830510238181804e-09 273.3657384799072 1.0075018312744475e-09 2.634291238950297e-09 261.4676377925814 9.790763328281552e-10 2.4922605677068474e-09 254.55222275751612 -5.224362057933436e-12 3.776755969288336e-09 -72291.2372344707 1.215989446254738e-09 2.868830943756715e-09 235.92564496285297 8.165132845158311e-10 2.930926754319549e-09 358.9564076789643 1.0753329570292327e-09 2.867018227447718e-09 266.6167914511132 +r_4080 phosphatidate (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 2.8940684456708954e-10 5.858058135721894e-10 202.4160190297053 2.2502321781779431e-10 6.13635029671182e-10 272.69854000934885 2.38109534382449e-10 5.955521859688813e-10 250.11689998616845 2.49903045519892e-10 5.611425135526393e-10 224.54408764217044 2.6698420492840675e-10 6.011932929133686e-10 225.1793483717817 2.1852099306852288e-10 5.992065610351505e-10 274.2100667862395 2.584737116793024e-10 5.872576293691883e-10 227.20207233214492 1.9620576007522408e-10 5.385395178033314e-10 274.4769152530786 2.8928435450241686e-10 5.833008844583551e-10 201.6358214261745 +r_4081 phosphatidate (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 3.415465402448607e-11 1.010151581500898e-09 2957.581068678672 -2.9626823656019276e-11 1.0597157738019023e-09 -3576.8794728239463 5.0280791869019134e-11 9.103044249735231e-10 1810.441703752112 4.366951436737357e-11 9.290368434560619e-10 2127.426551256007 3.1692580711157816e-11 9.82705116577287e-10 3100.7418598489576 4.900539150681025e-11 8.84780387016883e-10 1805.475601381382 4.160856753334052e-11 9.71787692243083e-10 2335.54709967941 6.310954947735503e-11 7.922425767829042e-10 1255.3450045894826 6.633842530188054e-11 9.025238229197071e-10 1360.4842424472245 +r_4082 phosphatidate (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 3.73732616687357e-10 5.192430727577376e-10 138.93437435569246 3.574462064278704e-10 6.236888243245241e-10 174.48466737340496 3.4847017069619576e-10 5.224499522321574e-10 149.92673582027803 3.45191158857063e-10 5.018488092351627e-10 145.38286869710024 3.8425789947248007e-10 5.09330197762162e-10 132.54905064056842 3.746140038350973e-10 4.95657899163089e-10 132.31163119606032 3.84696831065493e-10 5.10542341499031e-10 132.7129054026737 3.004378914299853e-10 4.689751818796384e-10 156.09721518396734 3.890662073935884e-10 4.958585054406682e-10 127.44836123458198 +r_4083 phosphatidate (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 1.979634169819281e-10 1.555323901172039e-09 785.6622829025134 1.2331602338372671e-10 8.015910616637992e-10 650.029930959954 1.3981234167215979e-10 6.95487127611795e-10 497.4433009945675 1.4602823146302438e-10 6.77744067151147e-10 464.1185203443059 1.3767191667280573e-10 7.619633543562875e-10 553.4631701011235 1.3078816550048696e-10 7.031175946719594e-10 537.6003187913371 1.4606791676267635e-10 9.004983947291833e-10 616.4929401932026 1.1908843679188404e-10 6.372978020707045e-10 535.1466685085725 5.145787813362777e-11 1.3923178657884821e-09 2705.742864431484 +r_4084 phosphatidate (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 1.7787159831293724e-10 6.802952878896433e-10 382.4642575554812 1.6048212402594587e-10 6.310176524507394e-10 393.2012093438644 1.4603807933763967e-10 6.66482027544794e-10 456.37550874925535 1.5483180330559168e-10 6.41310882371669e-10 414.19841962695017 1.6707484757978907e-10 6.916063047168935e-10 413.9499839355572 1.3430012634047028e-10 6.91279796300455e-10 514.7275845057366 1.6002556712421443e-10 6.873493919294583e-10 429.5247342544499 1.14730387350069e-10 6.21448948875302e-10 541.6602900320707 1.9070921471737247e-10 6.774095775307804e-10 355.2054778971687 +r_4085 phosphatidate (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn -1.5525495799902707e-10 1.324177980426176e-09 -852.9054385718714 -2.0401152895980871e-10 1.3217936504479683e-09 -647.9014481129487 -2.1851286011405208e-10 1.4870074516674731e-09 -680.5125569686535 -1.3835849892214206e-10 1.251091557173505e-09 -904.2390362138342 -1.8150262056757678e-10 1.4424111439039355e-09 -794.7054094279035 -1.7368733254022823e-10 1.2925042154757011e-09 -744.1557173873579 -1.880468289794712e-10 1.332502768863081e-09 -708.6015627567689 -1.3111467276910887e-10 1.178350330417446e-09 -898.7173636107873 -2.2345138567701079e-10 1.4007431147909092e-09 -626.8670523330844 +r_4086 phosphatidate (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 1.870779958811548e-10 1.9346617496905622e-09 1034.1471430555607 1.7273934245112966e-10 7.84693219044382e-10 454.2643313965273 1.7191933424241942e-10 8.616605137631661e-10 501.2004714653901 1.6827658927194108e-10 6.307944521062399e-10 374.8557388971397 1.7357260775123567e-10 7.11272278313644e-10 409.7837138755441 1.5421664048660028e-10 6.474234999417554e-10 419.8142936449257 2.0069449911327437e-10 8.107416479134098e-10 403.9680467055639 1.5674517821570148e-10 5.656917731441023e-10 360.8989951612022 1.8634916817542277e-10 1.2390696980452627e-09 664.9182876302646 +r_4087 phosphatidate (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn -5.769053415377272e-10 1.9607657124284622e-09 -339.8765050783009 -4.5215146120240863e-10 1.737148926569867e-09 -384.1962429912884 -4.308600835445919e-10 1.7407030894637687e-09 -404.0065803133547 -5.495366967162155e-10 1.9095801937154953e-09 -347.48911312498115 -5.132163815737072e-10 1.9402062536445267e-09 -378.048387250452 -4.0481689367863427e-10 1.6964923444963475e-09 -419.0764691364674 -5.838033591099918e-10 1.936489832526631e-09 -331.7024135453434 -3.773648776252123e-10 1.6394587345689422e-09 -434.4492113007944 -5.451826080181555e-10 1.884560047919281e-09 -345.6750124091489 +r_4088 diglyceride (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 3.389540978179305e-10 1.3696170664972556e-09 404.0715469482084 2.505108898539813e-10 7.072664316294846e-10 282.32961530803664 2.505325325098593e-10 1.1646806085779551e-09 464.8819843515218 2.4743257980055616e-10 8.076778190404954e-10 326.42339165340576 2.779388598592644e-10 7.56902549255878e-10 272.32699653410793 3.2981899464297543e-10 1.3603779768429952e-09 412.4619864042659 2.6906268457180077e-10 9.837889800762563e-10 365.63560704893183 2.4819511477427604e-10 6.232160673280379e-10 251.099248224458 2.696504039409088e-10 9.934993001385942e-10 368.4397596364477 +r_4089 diglyceride (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 2.738139034367745e-11 1.2155353655958927e-09 4439.275545686699 6.473802608662142e-11 1.168255307010667e-09 1804.5890145731444 9.20988488705817e-11 9.505322044294586e-10 1032.078268171578 5.359556971767144e-11 1.0540609034149844e-09 1966.6940923802536 6.044443987619089e-11 1.124101242792563e-09 1859.7264613504133 4.036431585806657e-11 1.1087244653452404e-09 2746.793651213757 4.386507381966626e-11 1.7935525311793223e-09 4088.794056412164 6.041410185743509e-11 9.085906988746151e-10 1503.9381054090702 -1.2362866379945194e-10 1.6725308747554462e-09 -1352.8665791200283 +r_4090 diglyceride (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 1.8862317277680287e-10 1.3281441726088535e-09 704.125666564013 7.461606771027327e-11 1.2529610272466822e-09 1679.2107460176069 3.46034595185805e-11 1.875296518363336e-09 5419.390270375671 1.084696100802146e-10 1.4636156148305795e-09 1349.3324201573305 4.4435035883976876e-11 1.246599060570774e-09 2805.4417775778 1.2337126900965068e-10 1.2923890275288926e-09 1047.5607796721258 5.626480005685549e-11 2.1631687388302354e-09 3844.621746890342 2.249696272852744e-11 1.0690230969116499e-09 4751.855216242445 -1.1153935637409198e-11 1.325942026575628e-09 -11887.66072962219 +r_4091 diglyceride (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn 9.754109508815323e-11 1.244638045815582e-09 1276.014017159367 1.4312934692106646e-10 1.0694608858631603e-09 747.1988860907406 1.5363019564840435e-10 1.630810984899827e-09 1061.5172219347264 1.1559620760981574e-10 9.60861020711246e-10 831.2219237801842 1.2663354084316552e-10 8.437948429965804e-10 666.3280813111057 1.0574933209940467e-10 1.068334585844149e-09 1010.2518518414012 1.1035908658216211e-10 2.015379756412171e-09 1826.2019185087445 1.1983844380122313e-10 7.81303700813699e-10 651.9641577703171 1.4976573117115358e-10 1.1021419020711811e-09 735.910607488467 +r_4092 diglyceride (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 1.6557219538772195e-10 9.432148142298323e-10 569.6698120243543 1.7517793601444716e-10 1.512004140570888e-09 863.1247604414012 1.4976088270887247e-10 9.042424620093295e-10 603.7908201750728 1.4057372792690215e-10 1.018403533241865e-09 724.4622080246968 1.6457874360187134e-10 1.1613931821103135e-09 705.6762961563328 1.4992156448380857e-10 1.0507994921707121e-09 700.899497539727 1.5858602274141034e-10 1.391887028855372e-09 877.685816690779 1.4987809108787242e-10 8.564732995867555e-10 571.4466293039533 2.0158299578882696e-10 1.0457891951251915e-09 518.7883983134832 +r_4093 diglyceride (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn -1.6472490563160162e-10 1.624163027172149e-09 -985.9851010050064 -1.680963507875088e-10 1.5756990248142024e-09 -937.378484085029 -1.2963221518824107e-10 1.3944648956833355e-09 -1075.7086065824071 -2.018516191774357e-10 1.4799016453587028e-09 -733.1631281381048 -1.4535995367527856e-10 1.452588052175244e-09 -999.3041518300143 -1.3588472592266128e-10 1.6944956429040927e-09 -1247.00964836071 -1.7144977939331458e-10 1.5584121739696043e-09 -908.9613177013936 -1.3043411695615286e-10 1.373309644508578e-09 -1052.8761006372542 -1.0306677553575687e-10 1.7367237965409471e-09 -1685.047181803439 +r_4094 diglyceride (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn 1.1462472360198567e-10 9.731701298563752e-10 849.0054320528078 1.3189864395545679e-10 9.3694551322012e-10 710.3526504309885 9.858771120099386e-11 1.2883769209520923e-09 1306.833179568839 1.2543012383407232e-10 9.684047860264615e-10 772.0671529492664 1.4997945429539834e-10 1.0546759141702775e-09 703.2135962389865 1.169397218916585e-10 1.4679605517766863e-09 1255.313872848708 1.4061252780600147e-10 1.2498535806824064e-09 888.8636028269041 1.1224370489732832e-10 8.664164837990513e-10 771.9065265990466 1.5389173341660963e-10 1.1013069920836483e-09 715.6375249229493 +r_4095 diglyceride (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn -2.532684686400375e-10 2.0904279558061957e-09 -825.3802642828213 -3.4802482984411767e-10 1.9708813074831652e-09 -566.3047973806738 -2.2127761754746688e-10 1.556183627124456e-09 -703.2720454840555 -2.0483114088993127e-10 1.8561943301514181e-09 -906.207094334776 -2.485331058645146e-10 1.5884686757989611e-09 -639.1376594572877 -2.3253792821556919e-10 1.753255007238523e-09 -753.9651792258195 -2.4804149849424923e-10 1.904260672401415e-09 -767.7185809476815 -1.6723733862809818e-10 1.4560083126755359e-09 -870.6239435640638 -1.7733585812301342e-10 1.7614701481570267e-09 -993.2960918344778 +r_4096 sn-2-acyl-1-lysophosphatidylinositol (16:1) [endoplasmic reticulum membrane] SLIME rxn -2.882839662410561e-10 9.93934611473518e-10 -344.7762372751642 -3.285719362785513e-10 1.1999605781527144e-09 -365.2048290379345 -2.9820000000000606e-10 5.629743759973429e-10 -188.79087055577847 -2.4240000000000187e-10 5.3529458088222e-10 -220.83109772368644 -3.2663975259613576e-10 5.819794963435317e-10 -178.1716682424455 -2.361928129411056e-10 5.447809889694236e-10 -230.6509593521222 -3.0600000000000665e-10 5.596665483384492e-10 -182.89756481648269 -3.0066139772891985e-10 5.722455443896357e-10 -190.32890444605053 -2.1139999999999958e-10 5.276037463311282e-10 -249.57603894566188 +r_4097 sn-2-acyl-1-lysophosphatidylinositol (18:1) [endoplasmic reticulum membrane] SLIME rxn -2.8126872126007833e-10 1.6839255925578023e-09 -598.689248137457 -2.740817794450554e-10 1.1843545878351802e-09 -432.11722801610193 -3.0600000000000665e-10 5.60023861406884e-10 -183.01433379309543 -2.5188145148424e-10 5.40360667248999e-10 -214.5297575763767 -3.288094676923678e-10 5.813204223522218e-10 -176.79552429922776 -2.3780946769234884e-10 5.371088037358863e-10 -225.8567789364625 -3.2019053230766045e-10 5.611795793913876e-10 -175.2642638577986 -2.2980000000000088e-10 5.290065496626148e-10 -230.2030242221987 -2.2745680615408456e-10 5.334958400454052e-10 -234.5481979923709 +r_4098 phosphatidylglycerol (1-16:0, 2-16:1) [mitochondrial membrane] SLIME rxn 4.2778851472878085e-10 3.181383411150227e-09 743.6813522605282 8.069227766491412e-10 3.400986770478838e-09 421.4761150505512 7.348780844815975e-10 3.0565152591212526e-09 415.9214056951227 7.274930036201733e-10 2.840917349224389e-09 390.5078585068623 6.470917884771035e-10 2.838895394937885e-09 438.7160284662359 4.013678532509053e-10 3.388784125879393e-09 844.3088051102533 7.207641420942758e-10 2.909462685940178e-09 403.6636280887044 6.836720617839062e-10 3.174032778803184e-09 464.26246679163336 7.636689424226616e-10 2.796017417073596e-09 366.1295178776704 +r_4099 phosphatidylglycerol (1-16:1, 2-16:1) [mitochondrial membrane] SLIME rxn 5.03347768032566e-10 4.395023273586539e-09 873.1583912183323 1.109211903475672e-09 3.995173434839348e-09 360.1812622385882 1.1089618075202815e-09 4.525759578842982e-09 408.1077948899706 1.0206182845481152e-09 3.556565520068439e-09 348.4716640798895 1.068223383400537e-09 4.308017055655554e-09 403.2880315671048 5.350330025897161e-10 4.7299105529629755e-09 884.040896555694 1.1517535235068422e-09 4.211496193024623e-09 365.6595015400102 8.53494364892977e-10 4.3350078852383115e-09 507.91288888965215 1.082236416816461e-09 4.142149947682852e-09 382.7398416205143 +r_4100 phosphatidylglycerol (1-18:0, 2-16:1) [mitochondrial membrane] SLIME rxn -3.3918528935476547e-10 4.969548846683825e-09 -1465.1428003075932 2.7279667770064136e-10 3.6290576149057483e-09 1330.3159134834348 3.8676605627887376e-10 3.795133935932891e-09 981.2479338146592 3.702103422845849e-10 4.537895700168054e-09 1225.7614609479824 1.1195878285558764e-10 4.037049375266987e-09 3605.835355029055 -5.208669247950525e-11 3.7228249414947326e-09 -7147.362914163856 1.7644326364286408e-10 4.1034476132659976e-09 2325.6470825498427 8.231075702645942e-11 3.740016129467084e-09 4543.775643157829 6.729282163759442e-11 3.786061180795461e-09 5626.248221816731 +r_4101 phosphatidylglycerol (1-18:1, 2-16:1) [mitochondrial membrane] SLIME rxn -2.713110204901579e-10 3.977648836407792e-09 -1466.084506711767 3.4004804383823807e-10 2.758745176850216e-09 811.2810018582433 3.8078233550942405e-10 3.442997959977601e-09 904.1905673936886 1.6931239134285116e-10 3.912805344222644e-09 2310.997625861513 1.0174208571270247e-10 3.2712219062280823e-09 3215.210188894005 -1.7206760866094848e-10 3.5873934608676422e-09 -2084.874363504662 2.6830689143367727e-10 4.003495252951528e-09 1492.1328451755962 1.2368117059038274e-10 3.49188613157883e-09 2823.2964766670425 2.7307694057807173e-10 3.3760752687236822e-09 1236.3091741019684 +r_4102 phosphatidylglycerol (1-16:0, 2-18:1) [mitochondrial membrane] SLIME rxn -3.816832931073425e-10 4.277650286913636e-09 -1120.7329123810016 1.7297303984593934e-10 3.870942282208646e-09 2237.8876417136166 1.0912525696457919e-10 4.586452319969338e-09 4202.924645994693 2.4000405274389137e-10 3.535036877031558e-09 1472.907159948587 -6.950176712180219e-12 3.763207933568855e-09 -54145.500026982256 -7.46594632597573e-10 4.910971204793538e-09 -657.7828168556674 1.6917776442652318e-10 3.842726297722495e-09 2271.413333039672 1.0539652669233123e-10 3.925181757855156e-09 3724.20409005827 1.5470421227319301e-10 3.552792989103822e-09 2296.506951491357 +r_4103 phosphatidylglycerol (1-16:1, 2-18:1) [mitochondrial membrane] SLIME rxn -1.2521110506236488e-10 4.508750101687075e-09 -3600.918704009014 6.492381456610705e-10 3.5100593224932382e-09 540.6428051018487 6.409430697166132e-10 3.896498049109356e-09 607.9320041376147 5.740141918020673e-10 3.302071713804531e-09 575.2595947911962 4.5811358731004856e-10 3.6482039091796516e-09 796.3535704324282 1.505086778860923e-10 3.093791794303992e-09 2055.5570866454823 6.893146841673563e-10 3.791206937902509e-09 549.9965436659774 4.713759714325456e-10 4.350880224199577e-09 923.0169732616909 5.195212881389166e-10 3.6489791744906285e-09 702.3733690610416 +r_4104 cardiolipin (1-16:0, 2-16:1, 3-16:0, 4-16:1) [mitochondrial membrane] SLIME rxn 3.8223534214702916e-10 4.023106607123521e-09 1052.520832983573 -5.011212941112724e-10 3.5298088320197486e-09 -704.3821273410038 -4.199062545565452e-10 3.936992664310231e-09 -937.5884787589106 -4.843918806803331e-10 3.4951016724411794e-09 -721.5442314045961 -5.82188356110359e-10 4.097020488212869e-09 -703.7276587916235 -9.053934984880168e-11 4.36013403178667e-09 -4815.73375451445 -6.246140698694996e-10 4.5070375422751206e-09 -721.5715686994971 -1.190001324161911e-10 3.646675440072227e-09 -3064.429733000921 -2.1361424835568078e-10 3.6893371037105597e-09 -1727.1025374522717 +r_4105 cardiolipin (1-16:0, 2-16:1, 3-16:1, 4-16:1) [mitochondrial membrane] SLIME rxn 9.669398675710766e-10 3.3255003509122142e-09 343.9200784290516 1.0883259853451354e-10 3.131740529935148e-09 2877.57581102136 4.380221736873321e-10 3.469516641968554e-09 792.0869879169989 3.232014023022045e-10 2.8670338184262887e-09 887.0734464652827 3.664663714793571e-10 2.97140384060873e-09 810.8257869920565 7.12895277841697e-10 3.2170252225902787e-09 451.2619626728177 5.857334951011899e-10 3.203135463243655e-09 546.8588513433552 4.485599534432352e-10 3.1942188919468117e-09 712.1052308453648 8.223493105732822e-10 4.0397209687862e-09 491.2414854424819 +r_4106 cardiolipin (1-16:0, 2-16:1, 3-18:0, 4-16:1) [mitochondrial membrane] SLIME rxn 4.372018074737332e-10 2.512749756071317e-09 574.7345306257184 -1.0944798606385392e-11 2.0110636779623395e-09 -18374.606516642973 -1.7032413444209426e-10 2.592313485637584e-09 -1521.9883512861193 -7.772377325609998e-11 2.557933335494695e-09 -3291.0565562306138 -6.214059659779963e-11 3.053272716300894e-09 -4913.491153074976 3.166527746132562e-10 2.5825403703252663e-09 815.5748432899259 2.0426077860698848e-11 3.0960603143338438e-09 15157.390153157465 1.3673451707551778e-10 2.2641876724689062e-09 1655.9005881582973 7.896851801741069e-11 3.1701718502774403e-09 4014.475552876012 +r_4107 cardiolipin (1-16:0, 2-16:1, 3-18:1, 4-16:1) [mitochondrial membrane] SLIME rxn 3.878876726377424e-10 1.793073598831809e-09 462.2661985204164 9.112251899002298e-11 1.873762423805844e-09 2056.3110464615256 1.5585035463055618e-10 1.9455910564830314e-09 1248.3712732608544 1.5895308530708855e-10 1.7759887189603403e-09 1117.3037097891045 1.5404761184712794e-10 2.1505959051799232e-09 1396.0592309046035 3.0554150678241307e-10 2.13911163653168e-09 700.1050885223976 -1.2886306839562247e-10 2.9611922726435602e-09 -2297.9371122472458 2.465953398240977e-10 1.8019190782051154e-09 730.7190312235693 2.287229372558296e-10 2.113206861430012e-09 923.9155839741436 +r_4108 cardiolipin (1-16:0, 2-16:1, 3-16:0, 4-18:1) [mitochondrial membrane] SLIME rxn 1.8262969913520888e-10 2.1938673146998e-09 1201.2653610492907 2.0928475398225136e-10 3.695268319082677e-09 1765.665319030386 1.8484309801767328e-10 3.154687031391756e-09 1706.6837037594605 -1.023974020467302e-10 1.8781779362428904e-09 -1834.2046758039453 2.2357653280014678e-10 3.2440125589264996e-09 1450.962906659929 2.0734105632273563e-10 2.970350102244181e-09 1432.5913810435588 1.9581917187200126e-10 3.802373953058111e-09 1941.778180710294 1.9744624414192008e-10 2.579114492016206e-09 1306.236288881947 1.248354730810476e-09 4.469368135371119e-09 358.02068314904744 +r_4109 cardiolipin (1-16:0, 2-16:1, 3-16:1, 4-18:1) [mitochondrial membrane] SLIME rxn 5.31972078548582e-10 1.5636789248099563e-09 293.9400370553761 1.011740404292496e-09 1.8470943137914062e-09 182.5660323492832 1.033355851530623e-09 1.890823277469569e-09 182.9789103791159 3.440593255005837e-10 1.8087192681353167e-09 525.6998238614079 1.0510037906229788e-09 1.935151707918166e-09 184.1241416238006 7.671569207385842e-10 1.2959823629995923e-09 168.93315147986655 1.0743484144242306e-09 1.9178878130041403e-09 178.51637208698102 9.411980366814215e-10 1.9698467780252683e-09 209.291424466924 1.3255414953438367e-09 2.351524322951768e-09 177.40103431026867 +r_4110 cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) [mitochondrial membrane] SLIME rxn 9.570041898872406e-10 3.107629055588194e-09 324.72470741788 -8.070093157131327e-11 3.9893776472333445e-09 -4943.409660281353 4.751950445471946e-10 3.0718212689214846e-09 646.4337758085356 3.1189789752266555e-10 2.7628635955358022e-09 885.8230906590273 4.127483524737893e-10 2.819617334323397e-09 683.1323050532227 7.769829412696195e-10 3.064849497002701e-09 394.45518481971067 3.6799753653626755e-10 3.7192488120593727e-09 1010.6722036963492 4.854944030907595e-10 3.0587226047503837e-09 630.022217615262 6.25631419552206e-10 2.87707877033295e-09 459.8680118067298 +r_4111 cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) [mitochondrial membrane] SLIME rxn 1.327435254189853e-09 5.611876078470213e-09 422.7608134375787 5.948050528201528e-10 5.213749732851148e-09 876.5476534086529 1.169367501955357e-09 5.685654649496916e-09 486.2162356991837 7.17227494724952e-10 5.107720678233786e-09 712.1479190075578 7.142007556103671e-10 5.490847316457878e-09 768.8100682230884 1.020354928232e-09 5.750138523067411e-09 563.5429754850941 1.050285820283409e-09 5.830296071314251e-09 555.1151847161951 9.844637110039703e-10 4.878536362465845e-09 495.5526859888661 9.730382529679015e-10 5.223988701670137e-09 536.8739292351813 +r_4112 cardiolipin (1-16:1, 2-16:1, 3-18:0, 4-16:1) [mitochondrial membrane] SLIME rxn 7.515802610209406e-10 2.675721140772092e-09 356.0126947902296 2.726795697392645e-10 2.832136453042804e-09 1038.63170084612 6.148265011150543e-10 5.809132778815821e-09 944.840986567809 4.6012361033497244e-10 2.6585952659454304e-09 577.800227206328 3.6499273957673184e-10 2.8389050974412555e-09 777.7976900947195 5.247158935418619e-10 3.0068229440158304e-09 573.0382824350156 3.144409509249577e-10 3.4331220755329104e-09 1091.8177372998196 4.0401803790266487e-10 3.014598118864657e-09 746.1543386810189 5.396311307920941e-10 2.4516020020335147e-09 454.3107063587949 +r_4113 cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) [mitochondrial membrane] SLIME rxn 1.3495170597997615e-10 3.112730120160293e-09 2306.5511455054548 2.3190838658362813e-11 2.731709754646327e-09 11779.262470360249 -5.674799945549105e-10 5.253581846999137e-09 -925.7739299020852 2.8134077696154692e-11 3.143229690476074e-09 11172.321781515817 -1.08519738128069e-10 3.297436647215843e-09 -3038.559347908111 -1.0764359550933412e-11 3.170318569578671e-09 -29451.99437623544 -1.356033032214518e-10 3.798182536637794e-09 -2800.9513385046644 1.4687698521979342e-10 2.64788351195263e-09 1802.789938798252 2.0933335971474518e-10 3.2611661269746276e-09 1557.881711457056 +r_4114 cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-18:1) [mitochondrial membrane] SLIME rxn 5.845145975506573e-10 1.8508973160019403e-09 316.655447743806 4.494489199682058e-10 2.3422127900146313e-09 521.1299184299563 2.655803863007538e-10 2.456832162371381e-09 925.0804235178596 3.3592270388535036e-10 1.7756382446062041e-09 528.585363260301 3.289702350634501e-10 1.475348643176671e-09 448.4748119817323 3.7840248474940544e-10 2.2132727725894743e-09 584.899111868993 4.6420016732177647e-10 2.2619378411983416e-09 487.2763950622191 3.935870352349523e-10 1.5384724633894627e-09 390.8849442845773 4.399822479795374e-10 1.318134297126814e-09 299.5880636502675 +r_4115 cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-18:1) [mitochondrial membrane] SLIME rxn 9.183342302458171e-10 3.5473274825543403e-09 386.27847745638337 1.0733938966250855e-09 3.658916758588698e-09 340.87363176676257 1.1670935810618104e-09 2.921431302239583e-09 250.31679975325488 1.878258309313849e-09 3.838170015639205e-09 204.3472932666719 1.2669787407904495e-09 3.1407920425086166e-09 247.89619126119845 1.123075722848246e-09 2.956900680554203e-09 263.28595840850085 1.2203528059786339e-09 3.009923568978589e-09 246.6437209168253 1.29141436480207e-09 3.503990561709966e-09 271.3296876054967 7.450483330270104e-10 3.566853690512877e-09 478.7412483726162 +r_4116 cardiolipin (1-18:0, 2-16:1, 3-16:0, 4-16:1) [mitochondrial membrane] SLIME rxn 4.205111456350956e-10 2.213354904785587e-09 526.3486896269467 -1.3786588495934002e-10 2.7580478762435277e-09 -2000.529628527712 -1.9997670299450024e-10 3.228322299071832e-09 -1614.3491970465263 -3.0949662613672817e-10 3.860526816659517e-09 -1247.3566722998876 -9.954306159763064e-11 2.774838979579666e-09 -2787.576487044391 3.0837139773742613e-10 2.4035877895796647e-09 779.4457615768521 2.1389960312023813e-11 3.4043118081108963e-09 15915.465753329388 1.8635354992388142e-10 2.4152176994015397e-09 1296.0406176260483 1.3231202793401892e-11 3.1743823287872926e-09 23991.638389597407 +r_4117 cardiolipin (1-18:0, 2-16:1, 3-16:1, 4-16:1) [mitochondrial membrane] SLIME rxn 7.328310383071775e-10 2.715302929246166e-09 370.5223697291059 2.9050600225155257e-10 3.231321940885674e-09 1112.308150551614 5.17819147851649e-10 3.128356857214453e-09 604.1408221757571 4.364843743236551e-10 2.561548730382552e-09 586.8592052926855 3.7193521068831676e-10 3.085043995721808e-09 829.4573643652919 5.57827407116219e-10 2.714593382093983e-09 486.636788989541 6.711352627487519e-10 2.555155981326449e-09 380.7214615517833 4.266472740767101e-10 3.066822751319482e-09 718.819253669502 6.404269923975172e-10 2.4919016243689354e-09 389.1000307529504 +r_4118 cardiolipin (1-18:0, 2-16:1, 3-18:0, 4-16:1) [mitochondrial membrane] SLIME rxn -4.734512479683396e-10 5.518480052178156e-09 -1165.5857019828118 -1.7455362935425982e-09 7.199808563210739e-09 -412.4697143133353 -2.4478871072333526e-09 8.069032029671135e-09 -329.6325229144617 -7.603056151114756e-10 5.931503925238062e-09 -780.1473259366088 -1.6272536996802561e-09 7.079001881011371e-09 -435.02754870997336 -1.7675311188706627e-09 7.415860432684219e-09 -419.5603886975677 -1.0405668858176671e-09 6.4912354631107265e-09 -623.8172242056288 -1.371540743695438e-09 6.835075180359317e-09 -498.3501373749274 -2.240829518428031e-09 8.128068399772651e-09 -362.7258715100553 +r_4119 cardiolipin (1-18:0, 2-16:1, 3-18:1, 4-16:1) [mitochondrial membrane] SLIME rxn 2.2128578341552926e-10 2.687022335247252e-09 1214.276983262669 -3.40925660965308e-11 2.4139351999973528e-09 -7080.532433852173 3.4685848452643784e-11 2.9113189023179043e-09 8393.391057718241 1.8754569971028176e-10 1.926820004789999e-09 1027.3869290346445 1.8275311385358016e-11 2.358044823972598e-09 12902.898201022384 9.626367217716319e-11 2.507405186285222e-09 2604.726299730812 1.3930003277798492e-10 2.482209792074167e-09 1781.9161579310537 1.9465238184097384e-10 1.9163810747469107e-09 984.5145775367632 1.6053655980291928e-10 2.3071174713285686e-09 1437.1290092181323 +r_4120 cardiolipin (1-18:0, 2-16:1, 3-16:0, 4-18:1) [mitochondrial membrane] SLIME rxn 2.4586010882108057e-10 2.130320805901542e-09 866.4768010217701 6.520245795548107e-10 3.3420637764744957e-09 512.5671456674821 3.768984725879067e-10 2.506119819229358e-09 664.9323362924582 8.960640031436504e-10 3.345140398826493e-09 373.31489570954494 5.171777166571384e-10 3.1824869302865358e-09 615.3565453007244 2.6260090958701677e-10 2.153487408671181e-09 820.0609099404473 4.6067744060971026e-10 3.3123546105352674e-09 719.0181933266235 3.822327837712081e-10 2.517370363501433e-09 658.5961409862341 9.780455848369528e-11 2.102558134547985e-09 2149.754742667231 +r_4121 cardiolipin (1-18:0, 2-16:1, 3-16:1, 4-18:1) [mitochondrial membrane] SLIME rxn 3.2862741151128165e-10 2.4906438817500155e-09 757.8929190039621 1.0465014563764054e-09 2.1981648489988204e-09 210.04890491124013 8.860744951440892e-10 2.357337638197561e-09 266.0428272246142 1.2433068584023472e-09 2.6774956522943924e-09 215.35276140396928 1.05708255457979e-09 2.237784164404298e-09 211.69436149609515 5.506505166839354e-10 1.743620814326365e-09 316.6474490619929 9.880310299016966e-10 2.544459003420613e-09 257.5282482447715 9.78234175008714e-10 2.0731371027691323e-09 211.92646461678413 4.2205926074761825e-10 1.9084806370598837e-09 452.1830971506893 +r_4122 cardiolipin (1-18:1, 2-16:1, 3-16:0, 4-16:1) [mitochondrial membrane] SLIME rxn 4.2663237445404444e-10 1.5456138570089323e-09 362.2823652299789 2.082147537487241e-11 2.39300910789464e-09 11492.98531833412 1.5130494865015892e-10 1.907363985209336e-09 1260.6091223225385 1.6290673753225842e-10 2.271206753903166e-09 1394.17607172535 1.3486730156000338e-10 1.9032496870306674e-09 1411.2017257080647 3.57610319289199e-10 1.529976064692329e-09 427.8333096576666 8.125484355324538e-11 2.625327162853183e-09 3230.979284493774 1.9070337954183167e-10 2.3995971963230004e-09 1258.287714715951 2.506895653317035e-10 1.788573435197781e-09 713.4614609232758 +r_4123 cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) [mitochondrial membrane] SLIME rxn -4.3380875708248656e-12 3.558634798169966e-09 -82032.34121189741 -1.3300038333293953e-10 3.320572367090594e-09 -2496.6637568090414 5.2741335627206015e-11 3.209377436279776e-09 6085.127344830181 -1.4828647756453898e-11 3.378964023775843e-09 -22786.73065320613 -1.1758391462718348e-10 3.3672454802271364e-09 -2863.695677171037 -3.9938332376233246e-11 3.110532699186574e-09 -7788.338956880458 -3.7432720510704327e-10 4.3616799215125765e-09 -1165.2051632916452 1.1158627095789224e-10 3.5050144920044162e-09 3141.080405247214 1.2314935700210698e-10 3.712363763153085e-09 3014.52143439902 +r_4124 cardiolipin (1-18:1, 2-16:1, 3-18:0, 4-16:1) [mitochondrial membrane] SLIME rxn 2.6138981494788867e-10 2.363448084571574e-09 904.185224295276 -3.2218546365660244e-11 2.9379748956838467e-09 -9118.893392456876 1.1095185060572994e-10 2.2606703736966644e-09 2037.5238099723192 2.1458400922365403e-10 1.6952846429802802e-09 790.0330733467375 -8.264771215313767e-11 2.9075514340211263e-09 -3518.0059535510595 1.147467263905398e-10 2.618003719344202e-09 2281.5498112197483 -2.2578721567055923e-11 3.196796068099532e-09 -14158.44585622554 1.4172055338556158e-10 2.317539770811027e-09 1635.288400621738 1.993004932110899e-10 2.124339347298593e-09 1065.8976869909654 +r_4125 cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) [mitochondrial membrane] SLIME rxn -5.842128808845886e-10 4.367862116216077e-09 -747.6490606647455 -4.2391235903936145e-10 3.5509673260477047e-09 -837.6654396429116 -6.481060604502654e-10 4.296791800520939e-09 -662.976642671075 -4.4306002695001106e-10 3.5749783837676317e-09 -806.8835296150478 -6.603582245006343e-10 4.2612523689216625e-09 -645.2940556837978 -6.616946141762788e-10 4.132386117026083e-09 -624.5156041008964 -8.60554229653186e-10 4.9757978999789725e-09 -578.2085228939354 -5.680461078946537e-10 4.050368876867742e-09 -713.0352308687764 -7.216352681924002e-10 4.449405264957166e-09 -616.5725902092246 +r_4126 cardiolipin (1-18:1, 2-16:1, 3-16:0, 4-18:1) [mitochondrial membrane] SLIME rxn 1.780673000770248e-10 2.046533399066162e-09 1149.3033241818762 -2.575775950171276e-10 3.217563999143242e-09 -1249.1629945257043 -2.7365366452549704e-11 2.4857556700378715e-09 -9083.582616545838 -5.846244568407426e-11 2.801148720399145e-09 -4791.36424694974 -2.9266221778549665e-11 3.1508948503312403e-09 -10766.31918589728 1.2491920233845518e-10 1.966799952891565e-09 1574.457662291768 -1.0835166239059995e-10 2.9208135969885752e-09 -2695.679542469087 9.113591855506222e-11 2.235685419859597e-09 2453.1331392779543 7.261532922076396e-11 2.189458625743227e-09 3015.1465940295748 +r_4127 cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-18:1) [mitochondrial membrane] SLIME rxn -8.132398288854341e-10 4.964159664745543e-09 -610.4176761176402 1.9819790018851358e-10 2.6753292416119e-09 1349.8272378603876 1.3735934473700638e-10 2.496238003390508e-09 1817.304827836725 9.228888885663787e-11 3.920854633004842e-09 4248.457947191802 3.208390002739231e-10 2.2378799197847e-09 697.5086937292731 4.5882844450580927e-10 3.088151037904632e-09 673.051349558502 1.1062986385708944e-10 3.8043496047855156e-09 3438.808900370642 4.51585956909606e-10 3.647915662848513e-09 807.800952849098 1.6440440665321514e-10 2.623307538615561e-09 1595.643080388356 +r_4128 cardiolipin (1-16:0, 2-18:1, 3-16:0, 4-16:1) [mitochondrial membrane] SLIME rxn 3.706038409739632e-10 3.413520744155743e-09 921.0699854553206 8.241736586217445e-11 2.846639542389681e-09 3453.931720106272 4.630964357305445e-11 3.2782307468397383e-09 7078.937547140175 -2.250952411745228e-12 2.9663658409896195e-09 -131782.69898161513 -2.802438467584473e-10 2.8671617563684606e-09 -1023.0953469746564 1.4631423253946682e-10 2.4851626097937342e-09 1698.5105048638286 -1.8311805265902267e-10 2.794947431065769e-09 -1526.309061548474 3.3878553806815443e-10 2.731207524610623e-09 806.1759484140609 -3.1858928099207584e-10 3.099973413763305e-09 -973.0312972583688 +r_4129 cardiolipin (1-16:0, 2-18:1, 3-16:1, 4-16:1) [mitochondrial membrane] SLIME rxn 5.72549490456322e-10 1.195580596443645e-09 208.8169872425818 2.4950987778761145e-10 2.25322583050536e-09 903.0607727776444 3.0469122540699715e-10 1.7728084675814327e-09 581.8377162694363 3.649298028477939e-10 1.754990807597772e-09 480.91188878036064 2.8822721971854603e-10 2.035715609206788e-09 706.2884661603665 3.940511073422827e-10 1.7701011673500615e-09 449.20598733719766 2.750103014044766e-10 2.325117416178197e-09 845.4655713999916 3.1840625663778096e-10 2.38088873808904e-09 747.7518699632652 3.868552161570596e-10 1.8084315741448983e-09 467.4698695055704 +r_4130 cardiolipin (1-16:0, 2-18:1, 3-18:0, 4-16:1) [mitochondrial membrane] SLIME rxn 1.9458629874545648e-10 2.945001710889854e-09 1513.4681783234332 1.0869487491012943e-10 1.8715938501402883e-09 1721.8786549851131 2.210840290801148e-10 2.668960442515706e-09 1207.2153984259753 6.101007325388342e-11 2.3416839959681767e-09 3838.1924018082095 2.249332165966622e-10 2.981965310162225e-09 1325.7114068258406 1.8207066418691508e-10 2.7988936925663263e-09 1537.2568145810471 2.6276387595932817e-10 2.3813467403589114e-09 906.268691487679 -2.1894099279194267e-10 2.9893786753041322e-09 -1365.3809810504092 -5.997582665226519e-12 2.0484639895917102e-09 -34154.82710173438 +r_4131 cardiolipin (1-16:0, 2-18:1, 3-18:1, 4-16:1) [mitochondrial membrane] SLIME rxn 1.5717365222780919e-10 2.5345016453887183e-09 1612.548674325633 -6.73472848928144e-11 3.036601367215926e-09 -4508.869766685896 -6.336663313859698e-11 3.313340851177374e-09 -5228.841563872201 1.772384973909633e-11 1.812299713919649e-09 10225.203556775645 2.2267046710954148e-11 2.729721365309412e-09 12259.018453338678 1.437857447882267e-10 1.900721041934244e-09 1321.9120189791422 3.933122142887896e-11 2.9156522662170197e-09 7413.07327942834 5.836968516532253e-12 2.748005211498576e-09 47079.32214668117 1.5584882900747438e-10 1.8381079682626966e-09 1179.4172468081504 +r_4132 cardiolipin (1-16:0, 2-18:1, 3-16:0, 4-18:1) [mitochondrial membrane] SLIME rxn -2.0659228843974007e-09 7.195900764758613e-09 -348.3141030628329 -1.995461688797069e-09 6.943677067794974e-09 -347.9734593141125 -3.285356499936385e-09 8.502332111745259e-09 -258.7948099973288 -1.9114198170805604e-09 6.60196414906562e-09 -345.39581990675623 -2.982094458145177e-09 7.739351059008908e-09 -259.5273613104355 -1.513835151302985e-09 6.574433211960362e-09 -434.2899031180265 -1.589032444478952e-09 6.086453629968263e-09 -383.02890863654 -1.7738718031447707e-09 6.4860444388606675e-09 -365.6433586329081 -2.6877124634423008e-09 7.699539418676486e-09 -286.4718426321268 +r_4133 cardiolipin (1-16:0, 2-18:1, 3-16:1, 4-18:1) [mitochondrial membrane] SLIME rxn 9.225465252100664e-11 3.716322492306755e-09 4028.330702845082 6.751839738465015e-10 2.6801465708053483e-09 396.9505608281309 3.2624127270979103e-10 3.295209402509693e-09 1010.0528897338374 6.606995973764384e-10 2.2619988637030884e-09 342.364195874377 1.6442442496278686e-12 3.433469612766056e-09 208817.49250715828 2.7550514645577206e-10 2.9489576347299582e-09 1070.3820500875345 -2.4881356689249567e-10 4.8912797645625184e-09 -1965.841262456513 1.3434109042394688e-11 3.807011154233559e-09 28338.39700287964 -2.7946387872952715e-10 4.8693161163577285e-09 -1742.3776333793703 +r_4134 cardiolipin (1-16:1, 2-18:1, 3-16:0, 4-16:1) [mitochondrial membrane] SLIME rxn 9.236947672009255e-10 2.138437145536781e-09 231.5090678728096 9.162433608894483e-10 1.976433605522013e-09 215.71055135432343 9.558469036637767e-10 1.5519970503041815e-09 162.36878985069174 9.042178366707231e-10 2.624445126605298e-09 290.2447861754586 2.8439890058766497e-10 1.8606853836616782e-09 654.2519608257519 7.427559136905206e-10 1.7514295882219619e-09 235.8015003232568 2.829294832147546e-10 2.3982614514024082e-09 847.6534237974884 1.0002788931600984e-09 1.63217401026164e-09 163.17189350114623 4.2704862880543134e-10 1.728909179634005e-09 404.8506570481737 +r_4135 cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-16:1) [mitochondrial membrane] SLIME rxn 1.1476239113239682e-09 3.905240243407723e-09 340.289201442518 7.017450965859358e-10 3.677729527449074e-09 524.0833951447069 1.4113259694277142e-09 2.9812572110295916e-09 211.2380325743227 1.3645344425732534e-09 3.7729674957777555e-09 276.5021811148022 1.912080194934916e-09 3.995898611904948e-09 208.98174786235688 9.080201878287551e-10 3.1049646044271982e-09 341.9488515835473 2.257264622755451e-09 4.564240860544002e-09 202.20229451753053 9.818957138817959e-11 4.329777011508542e-09 4409.609849900798 8.232666500184246e-10 3.414827003521569e-09 414.7899108320671 +r_4136 cardiolipin (1-16:1, 2-18:1, 3-18:0, 4-16:1) [mitochondrial membrane] SLIME rxn 4.0013507910646015e-10 3.711054483537434e-09 927.4504229483136 2.806726512147352e-10 2.3139678906817142e-09 824.436538674856 8.983403323526497e-10 1.774810758429728e-09 197.5655210516601 3.5727420909481696e-10 2.409124863845301e-09 674.3069615769394 9.86805920586816e-10 2.0380535134248e-09 206.5303289032605 5.49009803043337e-10 2.145357508227865e-09 390.7685247759625 1.0325201503219975e-09 2.297388300459601e-09 222.50299906913648 2.8121870668954815e-10 2.060648449227231e-09 732.7565344015634 4.2548834123173975e-10 1.6152184047370122e-09 379.6151969901552 +r_4137 cardiolipin (1-16:1, 2-18:1, 3-18:1, 4-16:1) [mitochondrial membrane] SLIME rxn -6.224167991281846e-10 4.599070616674561e-09 -738.905283905648 9.421364252180056e-11 2.736686435599393e-09 2904.766615902933 2.6950822412761364e-10 4.048691224422206e-09 1502.2514572709767 4.0824067567115216e-10 3.4890989688419182e-09 854.6671551299492 2.6925865118583164e-10 3.2548406339567267e-09 1208.8156200821063 -1.2765518225696123e-10 3.544719669685602e-09 -2776.7926119523468 7.768884292383195e-10 4.272784224843318e-09 549.9868532000739 -4.1332126542730545e-11 3.0765157055533034e-09 -7443.400480187482 -1.0982920459639482e-10 3.097231265941582e-09 -2820.043427723458 +r_4138 cardiolipin (1-16:1, 2-18:1, 3-16:0, 4-18:1) [mitochondrial membrane] SLIME rxn 7.894061050129849e-10 2.26684595661853e-09 287.15840202189 -3.047142594896815e-10 4.348075360255266e-09 -1426.9353090128373 8.994831601225585e-10 3.208490848385284e-09 356.703826222618 6.188651144390043e-10 2.5668971342309235e-09 414.7748959089079 -1.7492911368941635e-10 3.832011070386265e-09 -2190.607949451991 -1.4975503413934488e-10 3.837367135263756e-09 -2562.4294751207776 7.758541303878682e-10 3.253604942946697e-09 419.3578168257146 3.823192407286916e-10 3.2045595811252044e-09 838.1894604669618 4.974415610883742e-10 3.296329988412914e-09 662.656731214965 +r_4139 cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) [mitochondrial membrane] SLIME rxn -5.531039617757797e-10 5.595720090101056e-09 -1011.6940895045476 2.2893483350876028e-10 4.8014626084864625e-09 2097.3053924984 1.5579442560497176e-09 4.53301636751337e-09 290.9613967194928 2.8182739433683847e-10 4.265278486866793e-09 1513.436441089526 -3.28070365318572e-10 5.542740866406428e-09 -1689.497575016921 -2.084346057180853e-09 7.910592720994853e-09 -379.5239611839787 2.907199968912949e-10 4.511687880343795e-09 1551.901461401979 1.4408147318182535e-09 3.857510679860082e-09 267.73120753645054 -1.9355983726157207e-10 5.7278995674864454e-09 -2959.2397103258054 +r_4140 cardiolipin (1-18:1, 2-18:1, 3-16:0, 4-16:1) [mitochondrial membrane] SLIME rxn -8.358621297575591e-10 4.159023456873088e-09 -497.572902133921 5.875999452711644e-10 2.036723402268684e-09 346.61735738058684 6.048722272929592e-10 1.7590445498330154e-09 290.81258329638155 -9.772103079938315e-10 3.132298559236516e-09 -320.5347440170768 -1.9968497950292425e-11 2.199263860603345e-09 -11013.666957214167 4.1540205746762606e-10 1.567091571497322e-09 377.2469450562246 1.6266540828136176e-11 2.4726950933261427e-09 15201.112021611449 9.018816507227642e-10 3.38262021075674e-09 375.0625381995435 1.22134528644016e-10 1.962773076246198e-09 1607.058297139762 +r_4141 cardiolipin (1-18:1, 2-18:1, 3-16:1, 4-16:1) [mitochondrial membrane] SLIME rxn -4.382426685725403e-10 3.772996022885301e-09 -860.9376250776398 1.7838677334343013e-12 2.982797217129341e-09 167209.5504181166 1.3462667254790476e-10 4.4927586408483195e-09 3337.198012711517 -8.183485311623562e-11 3.326326405025921e-09 -4064.681829759397 -1.1050882365548223e-09 4.441419985095099e-09 -401.9063671278855 -6.366922623160804e-11 3.138553658469647e-09 -4929.467254796853 -6.752859126617787e-10 4.545448633950091e-09 -673.1146835320859 -1.4211287753278282e-11 2.7550034245986982e-09 -19386.0223818434 -2.93697512681409e-11 2.996556243486126e-09 -10202.865581421069 +r_4142 cardiolipin (1-18:1, 2-18:1, 3-18:0, 4-16:1) [mitochondrial membrane] SLIME rxn -1.0515714849241296e-09 6.091524459282342e-09 -579.278208530145 -6.066011466960019e-11 2.746729830641112e-09 -4528.065674787846 4.5995801538252924e-10 2.079921712434421e-09 452.1981665445337 -5.1666805340472825e-11 2.7338023105012714e-09 -5291.216076717185 5.026690602950181e-10 2.356573505837945e-09 468.81212550755833 2.292436412549744e-10 2.336485957891241e-09 1019.2151656204516 6.307163769230781e-10 2.160441494720544e-09 342.53771961022505 -1.1722148168128615e-10 2.643532902029792e-09 -2255.1607982718574 -1.2610812231031748e-10 2.780228175620272e-09 -2204.638467916359 +r_4143 cardiolipin (1-18:1, 2-18:1, 3-18:1, 4-16:1) [mitochondrial membrane] SLIME rxn -1.184656257862659e-09 4.8587913202576155e-09 -410.1435575095667 -4.3692549105868926e-10 3.84786567531959e-09 -880.6686160599248 -1.4146083010575903e-09 4.734146817036876e-09 -334.66132027484423 -2.495306221396332e-09 5.108011198191361e-09 -204.7047835008001 -1.449850713643958e-09 4.832999378586089e-09 -333.3446218362131 -5.015858234569497e-10 3.447058303816296e-09 -687.2320035002246 -3.066545990435354e-09 5.871111303036821e-09 -191.45681562738625 -7.357140176926922e-10 4.848541562788491e-09 -659.0253068704919 -6.79216642416827e-10 4.31091057611224e-09 -634.6885966711465 +r_4144 cardiolipin (1-18:1, 2-18:1, 3-16:0, 4-18:1) [mitochondrial membrane] SLIME rxn -2.1228562931520677e-09 6.028965189745074e-09 -284.00251157807406 -9.338157929103103e-10 4.569973635649977e-09 -489.38705795575527 -2.937878457514662e-09 6.803410599886864e-09 -231.575631812975 -1.9836569670959394e-09 5.758029227036121e-09 -290.2734355056277 -5.79178654459635e-10 3.737276874157865e-09 -645.271859620705 -4.685082990811727e-10 3.6211155077431552e-09 -772.9031726534622 -2.781243964882061e-09 6.528868299655513e-09 -234.7463358875952 -1.9842748002200992e-09 6.606135695429603e-09 -332.92443640854776 -2.487095787175644e-09 7.023823176679634e-09 -282.41064187784724 +r_4145 cardiolipin (1-18:1, 2-18:1, 3-16:1, 4-18:1) [mitochondrial membrane] SLIME rxn -4.3252159277590287e-10 3.899591874119804e-09 -901.5947271192658 -5.889986190151e-10 4.342079043456382e-09 -737.1968122297183 -1.3409530582769578e-09 5.5249841255445844e-09 -412.0192046576074 -3.8396567140143655e-10 4.150577201788411e-09 -1080.97611607809 -3.5735520091959867e-10 3.4006464578795277e-09 -951.6152134146884 -7.54788057850828e-10 5.043256608273624e-09 -668.1685747166847 -4.493127386593176e-10 4.763459079043248e-09 -1060.1655971866503 -2.068204025411801e-09 5.791006280641895e-09 -280.001692748318 -3.0205914392749587e-10 3.591321079977153e-09 -1188.9463213334102 +r_4146 cardiolipin (1-16:0, 2-16:1, 3-18:1, 4-18:1) [mitochondrial membrane] SLIME rxn 7.169969981217987e-11 2.4071740301762515e-09 3357.300011690337 6.644938252954613e-10 1.9620483075858262e-09 295.2696071650354 6.188809137702725e-10 1.8610665196774675e-09 300.71480284303794 -2.3216864963681205e-11 2.311682424540374e-09 -9956.910324269036 6.360009295866923e-10 2.165492481946982e-09 340.4857416410124 3.803133695841903e-10 2.0018444040572166e-09 526.3670867647651 7.132398016287227e-10 1.722369371427076e-09 241.4853135640986 -4.3870652218204976e-10 2.6859676118382963e-09 -612.2470207369521 1.077118010189628e-09 2.975656168390748e-09 276.2609240808145 +r_4147 cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-18:1) [mitochondrial membrane] SLIME rxn -4.090736577016632e-10 3.917509468992107e-09 -957.6538100747472 2.0021667482755862e-10 2.6509036663765296e-09 1324.01742694992 3.324750389763854e-10 3.349702588197606e-09 1007.5049839863386 2.176222606655629e-10 2.950416645034798e-09 1355.751307798853 1.5425373716209503e-10 2.7663806534176075e-09 1793.39619532887 4.864137434577634e-10 3.50946284425118e-09 721.4974682465802 3.311283798405417e-10 2.727899823316446e-09 823.819397367901 -3.7082420788087986e-10 2.6749762254146924e-09 -721.3596546733478 -3.9518773533275036e-10 4.002596414179213e-09 -1012.8341687550104 +r_4148 cardiolipin (1-18:0, 2-16:1, 3-18:1, 4-18:1) [mitochondrial membrane] SLIME rxn -2.330724295706802e-10 3.7060264318141244e-09 -1590.0749988493403 7.652290857832344e-10 3.774883132680948e-09 493.3010523008603 5.115418050223993e-10 2.3750875012494484e-09 464.2997850675078 1.4167099171090331e-09 4.302761111956812e-09 303.7150414487895 5.6058898629424e-10 2.831068541158819e-09 505.01679668620136 1.2780566329185683e-10 3.050071514272012e-09 2386.4916747130937 7.13412602051784e-10 2.7248878853395672e-09 381.951184700516 4.4076591780822076e-10 4.0437432373242865e-09 917.4355534185692 -9.921160423994283e-11 2.643570474889521e-09 -2664.57789402947 +r_4149 cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-18:1) [mitochondrial membrane] SLIME rxn -8.525656248817413e-10 4.227441132146712e-09 -495.84935267981234 -2.7260856821940046e-10 3.467952907515118e-09 -1272.1364299613815 -4.964463918005171e-10 4.363890315093957e-09 -879.0254873777914 -1.3802897510627903e-09 4.6360632035252e-09 -335.8760868836084 -7.441515669032223e-10 4.060293350711236e-09 -545.6271989869075 -2.845972284219038e-09 4.7566557537669006e-09 -167.13640467065093 -5.281162944854262e-10 4.446649933117668e-09 -841.983097198372 -1.0202500446368815e-09 4.319102747526966e-09 -423.3376680776508 -6.99949642227692e-10 4.699889086904905e-09 -671.4610313888895 +r_4150 cardiolipin (1-16:0, 2-18:1, 3-18:1, 4-18:1) [mitochondrial membrane] SLIME rxn -8.043490351068218e-10 4.122984543817038e-09 -512.5864971379601 -2.475508058957464e-09 5.864745634856359e-09 -236.910787409282 -1.2794609254645863e-09 5.436856895276293e-09 -424.933406489308 -1.781801438174181e-09 5.479973163932046e-09 -307.5524043547409 -7.2692599699003e-10 4.428494213995268e-09 -609.2083970489783 -1.3483140699797924e-09 4.7284534748946805e-09 -350.6937723319571 -1.641084451347364e-09 6.2458470272342154e-09 -380.59266371735146 -7.13113230719279e-10 4.1882198561320055e-09 -587.3148436620047 -7.35692986416741e-10 4.341528269321938e-09 -590.1277230421541 +r_4151 cardiolipin (1-16:1, 2-18:1, 3-18:1, 4-18:1) [mitochondrial membrane] SLIME rxn -1.145736499319514e-09 5.353011975148308e-09 -467.2114380861232 -8.62424871986377e-10 4.989498023831715e-09 -578.542918450354 -1.5284498174363911e-09 6.777985536890769e-09 -443.4548952519238 -7.86718270407176e-10 4.8114363955554686e-09 -611.5831520050053 -7.252118043693108e-10 4.8009276240423605e-09 -662.0035133346382 -1.1349956980273827e-09 6.219330377031825e-09 -547.9607004538425 -1.286830659716482e-09 6.4873437846103155e-09 -504.1334487662597 -2.01262974792627e-09 7.67778359932689e-09 -381.4801807057537 -6.062096871276028e-10 4.2119289176570706e-09 -694.797362545361 +r_4152 Cytochrome c apocytochrome-c-lyase 9.859997999999993e-13 3.9059219293867837e-10 39613.820706523344 2.0892758600000008e-11 1.0592126781000719e-09 5069.759807113605 1.6078215699999988e-10 4.033478293320555e-09 2508.660394026532 -2.0394136495324064e-11 2.9155765646328304e-10 -1429.6151079018762 5.487203343219725e-12 4.069113276002831e-10 7415.641487080737 2.5366424266704267e-10 6.009255024898142e-10 236.8979940458472 -1.856438387708183e-11 2.8649312973691965e-10 -1543.240710997159 5.589994774726099e-13 3.490078100739105e-10 62434.37143302364 -2.245105480605065e-13 4.0028341999618605e-10 -178291.58739049896 +r_4153 (R)-Acetoin:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4154 Probable diacetyl reductase [(R)-acetoin forming] 2 (EC 1.1.1.303) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4155 Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial (Glu-AdT subunit B) (EC 6.3.5.-) (Cytochrome c oxidase assembly factor PET112) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4156 Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Peptidase M) 9.865999999999627e-10 1.7443200768512332e-10 17.680114300134793 9.991999999999583e-10 1.600140021878606e-10 16.01421158805717 4.781000000000196e-10 8.89510334806269e-10 186.05110537674813 9.86199999999963e-10 2.383713996788197e-10 24.17069556670337 9.886191310403472e-10 3.2721193521463433e-10 33.09787611234079 9.659999999999708e-10 2.76512733627904e-10 28.624506586740413 6.388000000000312e-10 7.715268049278281e-10 120.77752112207112 8.638000000000054e-10 5.060640079634522e-10 58.58578466814642 5.40000000000024e-10 8.558893090241994e-10 158.49802018965954 +r_4157 ADP-ribose 1''-phosphate phosphatase (EC 3.1.3.84) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4158 NADPH2:quinone oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4159 UDP-N-acetylglucosamine transferase subunit ALG14 (Asparagine-linked glycosylation protein 14) -1.5795738568152003e-10 9.128782645624903e-10 -577.9269266984908 -8.821919687771368e-11 6.028774763450724e-10 -683.3858136123819 -5.2087839979274775e-11 5.851003100312954e-10 -1123.2953992027713 -1.5753969426030138e-10 6.100606603830053e-10 -387.24250624417726 -3.459353717176088e-10 3.640515974165915e-10 -105.23688156230844 -3.6156750555305836e-10 5.63883950377776e-10 -155.95537257012404 -1.8112647737874083e-10 6.215645637145445e-10 -343.1660421545298 1.4895703145811368e-10 5.586302302211016e-10 375.0277679091551 -5.1161439024158796e-11 5.459476258794381e-10 -1067.1076425775234 +r_4160 ADP-ribose pyrophosphatase (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4161 Probable vacuolar amino acid transporter YPQ3 (PQ-loop repeat-containing protein 3) (Protein RTC2) (Restriction of telomere capping protein 2) 7.654318191713502e-10 6.829380095456594e-10 89.22257899926376 5.6800000000000065e-11 2.5453235028866367e-10 448.1203350152525 5.170000000000223e-10 5.073090502785139e-10 98.12554163994038 6.084000000000294e-10 5.066564715426092e-10 83.27686908983972 3.2780000000000827e-10 5.04378865147944e-10 153.86786612200473 4.6176839943341034e-10 5.12410236022422e-10 110.96693421445669 7.62600000000041e-10 4.371263614690737e-10 57.32052995922504 5.872000000000276e-10 5.012448596064152e-10 85.36186301198768 7.74400000000037e-10 4.241940925161568e-10 54.77712971541019 +r_4162 Probable vacuolar amino acid transporter YPQ3 (PQ-loop repeat-containing protein 3) (Protein RTC2) (Restriction of telomere capping protein 2) -1.1018601879802655e-10 8.088354691494435e-10 -734.0636116747781 -9.493429001094147e-10 1.4353412647972962e-09 -151.1931320739712 -1.062908436166227e-09 1.9114589778092117e-09 -179.83289178732988 -1.1795326578858943e-09 1.4182924142853503e-09 -120.241894516714 -4.7905751285959125e-11 1.341524818241946e-09 -2800.341884284651 -1.0563571907271666e-09 1.8484364055229821e-09 -174.98213878305415 -1.017080189192779e-09 1.691092951579182e-09 -166.26938264536875 -1.7309918598734e-09 2.441912535086761e-09 -141.070133932655 3.1056332265101575e-10 1.1095162655574615e-09 357.2592719856491 +r_4163 Probable vacuolar amino acid transporter YPQ3 (PQ-loop repeat-containing protein 3) (Protein RTC2) (Restriction of telomere capping protein 2) 1.1040815135807384e-09 8.540884791946417e-10 77.35737521993973 7.645814908414901e-10 8.41445765769926e-10 110.05311740463924 5.999605751368767e-10 5.727169715962886e-10 95.45910103603514 6.143498752766508e-10 7.407603687775549e-10 120.57630327408783 5.835165684387183e-10 6.49602901594336e-10 111.32552813923368 6.13922322723174e-10 5.639584499128045e-10 91.8615318321144 5.600926090879511e-10 5.873700524961432e-10 104.87016664130068 7.279796847011915e-10 1.5484846456687672e-09 212.7098706476077 3.4099883379084547e-10 5.69671271547613e-10 167.05959525275844 +r_4164 oxalate:CoA ligase (AMP-forming) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4165 Glucosidase 2 subunit alpha (EC 3.2.1.84) (Alpha-glucosidase II subunit alpha) (Glucosidase II subunit alpha) (Reversal of TOR2 lethality protein 2) 0.0 0.0 8.800000000000005e-12 9.759336500489743e-11 1109.0155114192885 2.400000000000001e-12 5.28658581675529e-11 2202.7440903147035 0.0 0.0 0.0 0.0 3.499999999999991e-11 1.8596213696147348e-10 531.320391318497 1.6e-12 3.9971984588086965e-11 2498.249036755435 0.0 0.0 9.400000000000006e-12 9.650649045810692e-11 1026.6647921075198 +r_4166 Glucosidase 2 subunit alpha (EC 3.2.1.84) (Alpha-glucosidase II subunit alpha) (Glucosidase II subunit alpha) (Reversal of TOR2 lethality protein 2) 0.0 0.0 8.800000000000005e-12 9.759336500489743e-11 1109.0155114192885 2.400000000000001e-12 5.28658581675529e-11 2202.7440903147035 0.0 0.0 0.0 0.0 3.499999999999991e-11 1.8596213696147348e-10 531.320391318497 1.6e-12 3.9971984588086965e-11 2498.249036755435 0.0 0.0 9.400000000000006e-12 9.650649045810692e-11 1026.6647921075198 +r_4167 Vacuolar cation-chloride cotransporter 1 (Vacuolar homolog of CCC family protein 1) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4168 Probable metabolite transport protein YBR241C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4169 Probable metabolite transport protein YBR241C 5.96600000000028e-10 5.687997421143183e-10 95.34021825583169 -2.650000000000036e-10 5.65719902249817e-10 -213.47920839615443 4.212353292283416e-10 5.384852350480296e-10 127.83477493079162 3.6480000000001103e-10 5.529756924343688e-10 151.5832490225746 5.820000000000273e-10 5.36034949134234e-10 92.10222493714927 2.0399999999999911e-10 5.983774821316521e-10 293.32229516257587 4.4248384434911274e-10 6.036721946104665e-10 136.4280758088376 3.770000000000119e-10 5.86975219222745e-10 155.69634462141283 6.412000000000318e-10 4.997124197981236e-10 77.93393945697116 +r_4170 UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase -1.5795738568152003e-10 9.128782645624903e-10 -577.9269266984908 -8.821919685549839e-11 6.02877476329893e-10 -683.3858137672651 -5.208783997918805e-11 5.851003100315334e-10 -1123.2953992050986 -1.5753969426307696e-10 6.10060660384506e-10 -387.2425062383074 -3.4593537171726195e-10 3.640515974159775e-10 -105.23688156223648 -3.615675055327621e-10 5.63883950356081e-10 -155.95537257287825 -1.8112647742002727e-10 6.215645637724982e-10 -343.16604210830394 1.4895703144336854e-10 5.586302303321241e-10 375.02776802081206 -5.1161439024158796e-11 5.459476258794381e-10 -1067.1076425775234 +r_4171 (5-glutamyl)-peptide:amino-acid 5-glutamyltransferase 5.1654514647261694e-05 0.0013802289467958 2672.039329419936 0.0001418177042512 0.0030479386807989 2149.1947686582967 4.5171578227036346e-05 0.0015995187493561 3540.984867335878 0.0001275548550358 0.0032166521807633 2521.7794962476764 0.0001339472426679 0.0047343447044966 3534.484630066182 0.0001094424876883 0.003868185088123 3534.445506334986 0.0001999400418962 0.0070673199940508 3534.719672469788 0.0006111656735843 0.0152684200389936 2498.245680168686 0.0002935561769948 0.0103756295134536 3534.461314924885 +r_4172 P-type cation-transporting ATPase (EC 3.6.3.3) (Cadmium resistance protein 2) (Cadmium-translocating P-type ATPase) (Cd(2+)-exporting ATPase) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4174 Probable ATP-dependent permease 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4175 Putative aryl-alcohol dehydrogenase AAD3 (EC 1.1.1.-) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4176 Putative aryl-alcohol dehydrogenase AAD3 (EC 1.1.1.-) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4177 Putative aryl-alcohol dehydrogenase AAD3 (EC 1.1.1.-) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4178 Putative aryl-alcohol dehydrogenase AAD3 (EC 1.1.1.-) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4179 Putative aryl-alcohol dehydrogenase AAD3 (EC 1.1.1.-) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4180 Benzyl alcohol:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4181 Manganese-transporting ATPase 1 (EC 3.6.3.-) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4183 D-Mannitol:NAD+ 2-oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4184 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4185 oxaloacetate carboxy-lyase (pyruvate-forming) 1.4764357882406654e-05 0.0010439977578514 7071.067811865219 2.687634546459268e-05 0.0019004446131526 7071.067811865619 4.541627154392912e-05 0.0022705864390535 4999.499874967265 0.0 0.0 0.0001339476699694 0.0066967135926465 4999.499874968207 5.472085309227538e-05 0.0038693486293862 7071.067811865764 0.0002013389088319 0.0100659384953155 4999.49987496786 0.0003055824950873 0.0152775964598156 4999.499874967983 0.0002935552662154 0.0146762951673995 4999.499874967525 +r_4186 L-methionine:thioredoxin-disulfide S-oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4187 L-proline:tRNA(Pro) ligase (AMP-forming) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4188 Glutathione-specific gamma-glutamylcyclotransferase (Gamma-GCG) (EC 4.3.2.-) 1.4764435322160057e-05 0.0006026321003161 4081.646789509168 1.7918068740967695e-05 0.0008957883511382 4999.357710298802 1.5138766116643108e-05 0.0007568609036704 4999.488715519732 3.354549111707457e-05 0.001369214960147 4081.6661630274566 4.464923938331165e-05 0.0022322367614394 4999.495606802583 1.8241068933329965e-05 0.0012897815871875 7070.756609174859 6.711293674133903e-05 0.0033553111684643 4999.499845158131 6.450383139932372e-12 4.5743859956089277e-10 7091.65005608781 9.785173991700632e-05 0.0048920959557569 4999.498179497123 +r_4189 4a-hydroxytetrahydrobiopterin hydro-lyase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4190 superoxide:superoxide oxidoreductase 1.1363999999999259e-09 9.145284645446724e-10 80.47592965018762 2.3853999999999004e-09 1.0031291510163287e-09 42.05286958230781 1.341399999999883e-09 8.65214285106223e-10 64.50084129314882 1.739199999999903e-09 1.097371498099446e-09 63.09633728723018 1.2245999999999095e-09 9.294770710055892e-10 75.90046309045057 1.762999999999908e-09 1.062759093764086e-09 60.28128722428483 1.0669999999999414e-09 7.38796429358478e-10 69.24052758749002 1.1271999999999243e-09 7.053507382379102e-10 62.57547358392102 1.9823999999999244e-09 1.0624104589077695e-09 53.59213372214538 +r_4191 2-Deoxy-D-glucose 6-phosphate phosphohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4192 Cytochrome c lysine N-methyltransferase 1 (EC 2.1.1.59) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4194 Zinc transporter YKE4 -3.941570079999928e-11 1.9464325731389912e-10 -493.8216329110725 -1.9585039999953133e-13 1.3848714593776298e-11 -7071.0678118653 -9.84439047711729e-10 1.8245147794279249e-10 -18.533547441752777 -1.0166156955276514e-09 1.4467397875950815e-10 -14.230940894968024 -3.7869907978245293e-10 4.860376857626961e-10 -128.34403665356277 -1.6249196847215875e-10 5.999263758441356e-10 -369.2037098725447 -8.672186693972449e-10 2.877411624565435e-10 -33.17977029444445 -9.846335915250903e-10 1.2872333247004448e-10 -13.073221711912757 -3.7943774338528205e-10 4.85334598292546e-10 -127.90888802006604 +r_4195 Zinc transporter YKE4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4196 NADH:ferricytochrome-b5 oxidoreductase 0.0025374377829588 0.0003011821899477 11.86953989455281 0.004118354337982 0.0003031471699038 7.360881192470438 0.0095480091243635 0.0004224140769779 4.424106339614276 0.0141828436430973 0.0005529112113692 3.898451010833643 0.0200438345662216 0.001242062769404 6.1967322934163445 0.0237376251716614 0.0012417643225754 5.231207054604203 0.0265801588893251 0.0016311722460617 6.136803970411493 0.0312813933510298 0.0026377527120436 8.432337659782611 0.0354265015334844 0.0025181238140889 7.10802282214874 +r_4197 NADH-cytochrome b5 reductase 1 (EC 1.6.2.2) (Microsomal cytochrome b reductase) (P35) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4198 Benzil reductase ((S)-benzoin forming) IRC24 (EC 1.1.1.320) (Increased recombination centers protein 24) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4202 L-methionine:oxidized-thioredoxin S-oxidoreductase 1.232174573116194e-05 0.0003402902063166 2761.7044998427714 6.590684161332e-06 0.0002350835812313 3566.907099122712 2.562886074710533e-06 0.000181289575972 7073.649420510111 1.4637083019135432e-05 0.0005173773649917 3534.7026748113053 7.560643698295801e-06 0.0005346829358206 7071.923465208697 2.1668467358894745e-05 0.0008844740882712 4081.8488618587658 1.1364984639942845e-05 0.0008036905545142 7071.637841811412 1.7249658594185322e-05 0.0012198028653453 7071.46091434231 1.6570698178591904e-05 0.0011717933400596 7071.478385705556 +r_4203 Vacuolar aminopeptidase 1 (EC 3.4.11.22) (Aminopeptidase yscI) (Leucine aminopeptidase IV) (LAPIV) (Lysosomal aminopeptidase III) (Polypeptidase) (Vacuolar aminopeptidase I) 9.81399999999965e-10 2.0164863608387388e-10 20.54703852495222 9.663999999999701e-10 2.0803772720154395e-10 21.527082698835923 9.81199999999965e-10 1.9301298091621247e-10 19.671115054649352 9.940758464764816e-10 7.199515876791262e-10 72.42421091217605 9.643999999999707e-10 2.629571624692034e-10 27.266400090129768 9.851999999999635e-10 1.6669288318178875e-10 16.919699876349465 9.769999999999663e-10 2.0119417441657136e-10 20.593057770376493 9.805999999999654e-10 1.9139217902840215e-10 19.517864473629302 9.663999999999701e-10 2.483613832207605e-10 25.69964644254637 +r_4204 Vacuolar aminopeptidase 1 (EC 3.4.11.22) (Aminopeptidase yscI) (Leucine aminopeptidase IV) (LAPIV) (Lysosomal aminopeptidase III) (Polypeptidase) (Vacuolar aminopeptidase I) 8.961999999999944e-10 4.909926422614961e-10 54.78605693611909 7.585513336085324e-10 6.493063247240781e-10 85.59820488815689 -1.1652590939465391e-10 9.918311248929951e-10 -851.1678905107945 6.139241535235105e-10 1.0683603804204539e-09 174.02155857344684 -7.782499142493691e-10 6.09601668283328e-10 -78.32980860284398 8.63682077572417e-10 5.166290442728117e-10 59.817038895251805 -7.409829668837711e-10 6.795619815706103e-10 -91.71087756963313 -5.915877733465839e-10 8.17470264348367e-10 -138.1824136972907 -8.172000000000221e-10 5.711824663642407e-10 -69.89506441069815 +r_4205 5-oxo-L-proline amidohydrolase (ATP-hydrolysing) 1.4764435322160057e-05 0.0006026321003161 4081.646789509168 1.791806874096769e-05 0.0008957883511382 4999.357710298803 1.5138766116643108e-05 0.0007568609036704 4999.488715519732 3.3545491117074564e-05 0.001369214960147 4081.6661630274566 4.464923938331165e-05 0.0022322367614394 4999.495606802583 1.8241068933329965e-05 0.0012897815871875 7070.756609174859 6.711293674133903e-05 0.0033553111684643 4999.499845158131 6.450383139932372e-12 4.5743859956089277e-10 7091.65005608781 9.785173991700632e-05 0.0048920959557569 4999.498179497123 +r_4206 threo-3-hydroxy-L-aspartate ammonia-lyase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4208 glutathione:dehydroascorbate oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4209 Glutathione S-transferase omega-like 2 (EC 2.5.1.18) (Extracellular mutant protein 4) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4210 urea hydro-lyase (cyanamide-forming) -1.5999999999999996e-11 1.2707174920448714e-10 -794.1984325280448 -1.2874685327207734e-10 5.106237394185562e-10 -396.6106560596619 2.0972184346828543e-11 4.735051158762593e-10 2257.776815450623 -3.01214690666137e-10 6.785418988763452e-10 -225.26852769888097 4.481401435486816e-11 3.9380118720048647e-10 878.7456175697587 -1.3813679886731014e-10 3.7523163304956286e-10 -271.63770706022984 -7.021162780272455e-11 5.117760622178108e-10 -728.9049951323752 -1.29874578149824e-10 5.745272745203656e-10 -442.37084940332807 -1.9199999999999983e-11 4.205552678859961e-10 -2190.3920202395648 +r_4211 D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5-phosphate-lyase (glutamine-hydrolyzing) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4212 D-ribulose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5-phosphate-lyase -1.4547999999998722e-09 8.574987001764091e-10 -58.94272066101761 -1.1085999999999267e-09 4.481586875670603e-10 -40.4256438361077 -1.6075999999998767e-09 9.362678887540127e-10 -58.24010255997042 -1.2063999999999056e-09 6.058650464343481e-10 -50.22090902141871 -1.2379999999998983e-09 6.724927131872033e-10 -54.32089767263801 -1.3707999999998747e-09 7.981445777260103e-10 -58.22472845973763 -1.4569999999942112e-09 8.522301679912637e-10 -58.49211859949551 -1.4161999999885524e-09 8.397133937859823e-10 -59.29341857031282 -1.4455999999942154e-09 8.53689871828121e-10 -59.0543630209973 +r_4214 L-cysteinylglycine dipeptidase 6.641894996942403e-05 0.0015055470066731 2266.7431619533454 0.0001597357729922 0.0031760484499698 1988.3138200512783 6.031034434368003e-05 0.0017691610157189 2933.42880889106 0.0001611003461529 0.0034947162068885 2169.2791420636822 0.0001785964820512 0.0052330619203654 2930.1035833745777 0.0001276835566217 0.004077057630694 3193.0952885135493 0.0002670529786375 0.0078216547124161 2928.877540448996 0.0006111656800346 0.015268420038736 2498.2456537594726 0.0003914079169118 0.0114686018844126 2930.089400055964 +r_4216 riboflavin-5-phosphate phosphohydrolase 4.406824168864255e-05 0.0018078967718546 4102.493547684745 2.650884934684284e-05 0.001900444583703 7169.094964619524 6.727348644141481e-05 0.0027806111139129 4133.294201028878 9.9221957295567e-05 0.0041016371974823 4133.799926224159 0.0002661123704911 0.0094686849474662 3558.152869778118 0.0002714909595134 0.0086486586741969 3185.615716154118 0.0002996346993987 0.0123269713439406 4113.999936815241 0.0007611754480601 0.024148740245686 3172.5590082059884 0.0007307402538822 0.0231982851474144 3174.628060267153 +r_4217 Fe(II):oxygen oxidoreductase; Fe2+:oxygen oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4218 D-aminoacyl-tRNA deacylase (DTD) (EC 3.1.1.96) (D-tyrosyl-tRNA(Tyr) deacylase) (Gly-tRNA(Ala) deacylase) (EC 3.1.1.-) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4219 D-aminoacyl-tRNA deacylase (DTD) (EC 3.1.1.96) (D-tyrosyl-tRNA(Tyr) deacylase) (Gly-tRNA(Ala) deacylase) (EC 3.1.1.-) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4220 4-nitrophenyl phosphate phosphohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4221 D-Iditol:NAD+ 2-oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4222 ATP:alpha-D-galactose 1-phosphotransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4223 3-Hydroxy-2-methylpropanoyl-CoA hydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4224 Sodium transport ATPase 5 (EC 3.6.3.7) 0.0005834901737741 0.0083127816705974 1424.6652376043137 0.001280643285129 0.0184223822055684 1438.5256549963226 0.0032872575055243 0.0410230545219464 1247.9416185986531 0.0030001588449861 0.0673505281738626 2244.8987421588645 0.0031910388623791 0.064596560695585 2024.311313069499 0.0337330036881387 0.1871747809006604 554.8713735399597 0.004121324028719 0.0835718851259519 2027.7921498913909 0.0045804504448477 0.096840276773145 2114.2085901633195 0.0152143842102662 0.1912960082235465 1257.336515101714 +r_4226 L-Alanine:2-oxoglutarate aminotransferase -0.0058425617548336 0.0056001912347341 -95.85163956719772 2.391598202267267 48.93577378904384 2046.1536449831776 -0.1694280460971502 0.0793215699015948 -46.81726061818111 2.954891981909606 54.69479961826227 1850.9915067323584 -0.6361725182531393 0.3033691432222745 -47.68661558271855 4.335571295311314 66.1904316862068 1526.683040774538 2.81569900403368 58.23799209909593 2068.331594238804 3.1205758024843395 59.91492461338481 1919.9958086480576 -1.5119765302650807 0.7031116114582453 -46.5028125360501 +r_4227 2-phenylacetamide amidohydrolase -5.199999999999999e-12 7.465972686102689e-11 -1435.7639780966715 -7.652463039852828e-10 4.290980121620777e-10 -56.073189759611054 -6.199999999999999e-12 7.850345571063667e-11 -1266.1847695263982 -7.560000000000048e-11 2.643834709733992e-10 -349.7135859436475 -6.599999999999999e-12 8.097994535877668e-11 -1226.968869072374 -1.2e-12 3.462368784447926e-11 -2885.307320373272 -8.400000000000003e-12 9.127489370710819e-11 -1086.6058774655737 -9.800000000000008e-12 9.851853216647464e-11 -1005.2911445558628 -9.800000000000008e-12 9.851853216647527e-11 -1005.2911445558696 +r_4228 Indole-3-acetamide amidohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4230 Probable amidase (EC 3.5.1.4) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4231 Acylamide aminohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4232 ATP:D-Gluconate 6-phosphotransferase 5.904876147780234e-05 0.0020869585467138 3534.2969005342225 0.000134382507334 0.0042478245372072 3160.995148459416 4.541624312202547e-05 0.0022705883791088 4999.507275421757 0.0001677129233596 0.0053014221979015 3161.0099518285315 0.0001339472116322 0.0066967148053154 4999.517887464951 0.0001094424253933 0.0054715366195094 4999.465792032969 0.0003020082370388 0.0123269724152822 4081.667618123634 0.0006111647236523 0.0216014564618893 3534.473706662685 0.0002935551680598 0.0146762944613772 4999.501306133795 +r_4234 Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19 (GPI-GlcNAc transferase complex subunit GPI19) (GPI-GnT subunit GPI19) (EC 2.4.1.198) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4236 (R)-lactate hydro-lyase -0.0002290641241042 0.0036819959317125 -1607.408382308348 -0.0004326958580629 0.0064061607237504 -1480.522774687224 -0.0002438823707999 0.0047042394586317 -1928.896887134881 -0.0007527915163367 0.0095665223496298 -1270.8063443890271 -0.000677385046468 0.0138146279421133 -2039.4055071252608 -0.0009669148044243 0.0148128434269481 -1531.9698653043608 -0.0013501589442184 0.0235000763899144 -1740.5414740645738 -0.0023101650608541 0.0378687825671324 -1639.224106052906 -0.0012749216268117 0.0283267142189696 -2221.8396506306485 +r_4237 Calcium-transporting ATPase 2 (EC 3.6.3.8) (Vacuolar Ca(2+)-ATPase) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4238 Calcium-transporting ATPase 2 (EC 3.6.3.8) (Golgi Ca(2+)-ATPase) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4241 Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A-glucosidase I) (Glucosidase I) 0.0 0.0 8.800000000000005e-12 9.759336500489743e-11 1109.0155114192885 2.400000000000001e-12 5.28658581675529e-11 2202.7440903147035 0.0 0.0 0.0 0.0 3.499999999999991e-11 1.8596213696147348e-10 531.320391318497 1.6e-12 3.9971984588086965e-11 2498.249036755435 0.0 0.0 9.400000000000006e-12 9.650649045810692e-11 1026.6647921075198 +r_4242 Initiation-specific alpha-1,6-mannosyltransferase (EC 2.4.1.232) (Outer chain elongation protein 1) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4243 Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4244 GDP-D-mannose:D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-6-mannosyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4245 2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate 6-phosphomannohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4247 ATP:L-threonyl,bicarbonate adenylyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4248 D-serine ammonia-lyase 9.593693553831396e-10 3.812573054171452e-10 39.74040897573635 7.99600000000028e-10 5.179705577537583e-10 64.77870907375438 -3.494000000000099e-10 5.386814230462048e-10 -154.17327505615043 4.1974745808207197e-10 1.3065886944151366e-09 311.27971575700724 -7.840000000000054e-11 3.6644275959447405e-10 -467.40147907458106 9.121999999999892e-10 3.6071759513045404e-10 39.54369602394853 -2.5920000000000315e-10 5.127064789786583e-10 -197.80342553188737 -1.8959999999999803e-10 6.84796049291911e-10 -361.1793508923619 -4.0580000000001415e-10 5.407262125765568e-10 -133.2494363175303 +r_4249 O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase; O3-acetyl-L-serine acetate-lyase (adding hydrogen sulfide) 2.1968844284760136e-05 0.0007141577469088 3250.775223548076 6.207607682592062e-05 0.0016585685633404 2671.8321262336594 3.437741528948472e-05 0.0010949749132232 3185.157767105845 5.589021661232353e-05 0.0017667096763884 3161.0356578916835 0.0001499997668857 0.0040152678697656 2676.849406589519 0.0001741381052839 0.0039241173401413 2253.451267166732 0.0001910083770435 0.0055265523240979 2893.355992883234 0.0002991870797237 0.0086423561042466 2888.612740973368 0.0001889356030241 0.0066907582614484 3541.290341446724 +r_4250 Dolichyl-diphosphate phosphohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4253 dolichyl beta-D-glucosyl phosphate:D-Glc-alpha-(1->3)-D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-glucosyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4254 nitric oxide, NADH2:oxygen oxidoreductase 2.6600000000000363e-10 4.43264364301176e-10 166.64073845908646 3.92000000000013e-10 4.886550488344069e-10 124.65690021285474 4.940000000000205e-10 5.00413911493834e-10 101.29836265056944 5.146000000000223e-10 5.014350680053062e-10 97.441715508217 6.938000000000356e-10 4.6139368962672254e-10 66.50240553858441 6.490000000000322e-10 4.773306704097251e-10 73.54863950842858 6.406000000000318e-10 4.815371383425515e-10 75.16970626639518 3.934000000000132e-10 4.897799678257417e-10 124.49922923887276 6.426000000000319e-10 4.80532436245948e-10 74.77940184343672 +r_4255 nitric oxide, NADPH2:oxygen oxidoreductase -2.6600000000000363e-10 4.43264364301176e-10 -166.64073845908646 -3.92000000000013e-10 4.886550488344069e-10 -124.65690021285474 -4.940000000000205e-10 5.00413911493834e-10 -101.29836265056944 -5.146000000000223e-10 5.014350680053062e-10 -97.441715508217 -6.938000000000356e-10 4.6139368962672254e-10 -66.50240553858441 -6.490000000000322e-10 4.773306704097251e-10 -73.54863950842858 -6.406000000000318e-10 4.815371383425515e-10 -75.16970626639518 -3.934000000000132e-10 4.897799678257417e-10 -124.49922923887276 -6.426000000000319e-10 4.80532436245948e-10 -74.77940184343672 +r_4260 Deaminated glutathione amidase (dGSH amidase) (EC 3.5.1.-) (Nitrilase homolog 1) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4261 Deaminated glutathione amidase (dGSH amidase) (EC 3.5.1.-) (Nitrilase homolog 1) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4262 citrate hydroxymutase 0.2719531217221357 0.0612270040768371 22.513808147933297 0.5541709736291095 0.2449931603884793 44.20894850989544 0.7849491097025397 0.1446117063052646 18.42306775277012 1.3586755798712289 0.4134575368054689 30.4309242714626 1.3914687128854242 0.4926280966970341 35.40346197763183 1.7231431444303495 0.402021523949109 23.330709653956955 2.5794303095049265 0.5401405640372806 20.940304610941418 3.0018676461643308 0.667853603288853 22.247936351964427 1.9850134672793864 0.5874639325564572 29.59495954259805 +r_4263 Anion/proton exchange transporter GEF1 (CLC protein GEF1) (ClC-A) (ClC-Y1) (Voltage-gated chloride channel) [Cleaved into: GEF1 N-terminal; GEF1 C-terminal] 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4264 succinate:NAD+ oxidoreductase 0.0017604117434099 0.0563098604987733 3198.675577436188 0.003611799816987 0.0986284010378573 2730.727228402548 0.0041509825889146 0.1239910676793832 2987.029336391474 0.0097114349786398 0.269269585391311 2772.706463911504 0.0085211571796564 0.2780443705067774 3262.9884022159063 0.0099806751126045 0.3281255982484676 3287.6092503409977 0.0121364912491753 0.3957582987101428 3260.8955140723488 0.012457711096933 0.3940468654415375 3163.0759645609933 0.0140634633779264 0.3733383539332994 2654.6686538059903 +r_4266 Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.9) (Hydroxylaminopurine sensitivity protein 1) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase) 1.771722965154378e-05 0.0008857728742766 4999.499874967463 4.837745467880508e-05 0.0019746061981586 4081.666163027364 4.087463877882822e-05 0.0016683663002948 4081.666163026666 5.978198579399859e-05 0.0024403469116615 4082.0773670361023 0.0001607372203616 0.0056812134527102 3534.4728743760747 9.849747029862584e-05 0.0040203379166167 4081.666163027212 0.0001812049640834 0.0073961817047182 4081.666163027436 0.000275024129784 0.011225566845556 4081.6661630272383 0.000264199612842 0.0107837462002207 4081.666163026835 +r_4267 2'-Deoxyguanosine 5'-triphosphate diphosphohydrolase 1.7717230250527842e-05 0.0008857729042228 4999.499874967667 1.6126212098107968e-05 0.0011402667681819 7070.890307313724 5.4499555124248986e-05 0.0019262719925222 3534.472874376175 2.01272868918459e-05 0.0014232141048113 7071.067811866399 0.0001205461465208 0.0049202912889565 4081.666175953932 9.849748664690543e-05 0.0040203385838988 4081.6661630270737 0.0002415976886311 0.008539204787576 3534.472881739142 0.0002751587728482 0.0112255706445147 4079.670267575421 0.0002641996760336 0.0107837487794926 4081.666163027326 +r_4268 dTTP diphosphohydrolase 7.972108796148032e-05 0.0018775178769351 2355.108196519196 9.634366716314154e-05 0.0027799128329553 2885.4131411129 0.0001225446785392 0.0028860765174374 2355.121863993429 0.0001610100723382 0.0040224113474216 2498.2358488547866 0.0002234979427843 0.0065465232963157 2929.120158673003 0.0001312917802496 0.0046404490243965 3534.4551011284507 0.0003020053735503 0.009546400811319 3161.003626886538 0.0005500491860263 0.015870586398477 2885.3031331850566 0.0004403336513142 0.0139189772104068 3161.006924831267 +r_4269 Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.9) (Hydroxylaminopurine sensitivity protein 1) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4270 superoxide:superoxide oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4271 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Man(9)-alpha-mannosidase) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4272 alpha 1,2-mannosyloligosaccharide alpha-D-mannohydrolase 0.0 0.0 8.800000000000005e-12 9.759336500489743e-11 1109.0155114192885 2.400000000000001e-12 5.28658581675529e-11 2202.7440903147035 0.0 0.0 0.0 0.0 3.499999999999991e-11 1.8596213696147348e-10 531.320391318497 1.6e-12 3.9971984588086965e-11 2498.249036755435 0.0 0.0 9.400000000000006e-12 9.650649045810692e-11 1026.6647921075198 +r_4273 ethylnitronate:oxygen 2-oxidoreductase (nitrite-forming) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4274 O-Succinyl-L-homoserine succinate-lyase (deaminating; 2-oxobutanoate-forming) 2.07753972221156e-05 0.000641383639978 3087.226843948491 2.948346660738993e-05 0.0007934480557164 2691.1626990213667 2.174304315443704e-05 0.0007913302496746 3639.4640991787446 9.043490518479532e-05 0.0020204872982962 2234.189657375722 6.558569621049301e-05 0.0023180305222483 3534.353763370532 9.47817169071532e-05 0.0028022213565629 2956.4998904883387 0.0001500296147604 0.0043287574358033 2885.268646937482 0.0001949214690248 0.00585409818747 3003.3111369188405 7.170470221553499e-05 0.0035847686827356 4999.349515406043 +r_4275 Fe(II):NADP+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4276 Fe(II):NADP+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4279 8-oxo-dGTP diphosphohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4282 ATP:D-fructose-6-phosphate 2-phosphotransferase 2.1480590196569954e-10 2.0238783646989864e-09 942.1893654589444 6.168000000000301e-10 4.866262642153735e-10 78.89530872492702 1.2000000000000012e-11 1.0889615087014804e-10 907.4679239178996 9.840000000000079e-11 3.2115116006878216e-10 326.37313015119867 1.2200000000000012e-11 1.0978875495305758e-10 899.9078274840776 1.8599999999999807e-10 3.8914558568404215e-10 209.21805681937963 1.5799999999999996e-11 1.2471355457262855e-10 789.3262947634722 1.3800000000000003e-11 1.1667168661029536e-10 845.4470044224298 1.6199999999999993e-11 1.2625667566363166e-10 779.3621954545167 +r_4283 ATP:D-fructose 6-phosphotransferase 2.1480590196569954e-10 2.0238783646989864e-09 942.1893654589444 6.168000000000301e-10 4.866262642153735e-10 78.89530872492702 1.2000000000000012e-11 1.0889615087014804e-10 907.4679239178996 9.840000000000079e-11 3.2115116006878216e-10 326.37313015119867 1.2200000000000012e-11 1.0978875495305758e-10 899.9078274840776 1.8599999999999807e-10 3.8914558568404215e-10 209.21805681937963 1.5799999999999996e-11 1.2471355457262855e-10 789.3262947634722 1.3800000000000003e-11 1.1667168661029536e-10 845.4470044224298 1.6199999999999993e-11 1.2625667566363166e-10 779.3621954545167 +r_4284 ATP:beta-D-glucose 6-phosphotransferase 0.0 0.0 0.0 0.0 -4e-12 9.157334293028108e-11 -2289.333573257027 -6.399999999999999e-12 1.0373616649196217e-10 -1620.8776014369096 -8.200000000000003e-12 1.0646608382673372e-10 -1298.3668759357768 0.0 0.0 -4.6e-12 7.334791055780814e-11 -1594.5197947349595 -2.800000000000001e-12 6.318986146304394e-11 -2256.780766537283 -6.000000000000003e-13 3.1620246172249993e-11 -5270.041028708331 +r_4285 ATP:alpha-D-glucose 6-phosphotransferase 0.0 0.0 0.0 0.0 4.000000000000001e-13 5.2918806487071e-11 13229.701621767745 -6.000000000000003e-13 5.477444703518056e-11 -9129.074505863426 1.6e-12 5.6551565990016855e-11 3534.4728743760534 0.0 0.0 2e-13 2.449653069320572e-11 12248.26534660286 4e-13 2.828427124746256e-11 7071.067811865639 6.000000000000003e-13 2.448999697816261e-11 4081.666163027101 +r_4286 ATP:D-glucosamine 6-phosphotransferase 9.979999999999591e-10 5.288250478052538e-11 5.298848174401558 9.989999999999588e-10 4.2418862219229535e-11 4.246132354277407 9.943999999999603e-10 8.700663210816392e-11 8.749661314176125 9.943999999999603e-10 9.148942049664468e-11 9.200464651714434 9.937999999999603e-10 8.101155827728824e-11 8.15169634506857 9.9539999999996e-10 8.354780695631979e-11 8.39339029097078 9.957999999999599e-10 6.76999014425557e-11 6.798544029178393 9.903999999999618e-10 1.07285329977618e-10 10.832525240066856 9.883999999999624e-10 1.1605228833040855e-10 11.741429414246555 +r_4287 ATP:D-fructose 6-phosphotransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4288 alpha-D-Glucose 6-phosphate ketol-isomerase 0.0 0.0 0.0 0.0 4e-12 9.157334293028108e-11 2289.333573257027 6.399999999999999e-12 1.0373616649196217e-10 1620.8776014369096 8.200000000000003e-12 1.0646608382673372e-10 1298.3668759357768 0.0 0.0 4.6e-12 7.334791055780814e-11 1594.5197947349595 2.800000000000001e-12 6.318986146304394e-11 2256.780766537283 6.000000000000003e-13 3.1620246172249993e-11 5270.041028708331 +r_4291 D-Glyceraldehyde:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4292 4-Aminobutyraldehyde:NAD+ oxidoreductase -0.0001901030155312 0.0050327405598659 -2647.3754484120136 -0.0004434596109158 0.0124190981898036 -2800.502657762949 -0.0004311558746385 0.0112081443660902 -2599.5573817676054 -0.0006038238508579 0.0159021466785627 -2633.5737907614925 -0.0019635416200737 0.0355236488194658 -1809.1619987220529 -0.0002462428172292 0.0100508447602518 -4081.680380912884 -0.0012035171162455 0.036822280839329 -3059.5560580141487 -0.0035184938672251 0.0829087313981419 -2356.369927781868 -0.0020924883794327 0.0601361030943246 -2873.9038020668804 +r_4293 4-aminobutanal:NAD+ 1-oxidoreductase; 4-aminobutyraldehyde:NAD+ oxidoreductase 4.429289015278826e-05 0.0031319934533559 7071.097511478997 0.0003225159043536 0.0113992467905421 3534.4758620156617 0.0003289703634568 0.0104064078761337 3163.3268622687174 0.0004025454280369 0.0142278698276009 3534.475573846295 0.0006577565117836 0.0246864940738747 3753.135640866612 3.0363962291298857e-11 5.821782572990522e-09 19173.32961073668 0.0006011594272692 0.0300553160850135 4999.558307109762 0.0026789785324765 0.0774335520123293 2890.4133076702 0.0012956525591225 0.052904151021808 4083.2050729429457 +r_4294 Indole-3-acetaldehyde:NAD+ oxidoreductase -9.399999999999991e-12 4.211260018354077e-10 -4480.063849312852 -5.195896446143502e-10 7.852004978925651e-10 -151.11935082450617 -4.70200000000013e-10 6.563521308138842e-10 -139.58998953931646 -2.8419999999999965e-10 7.73013499218439e-10 -271.99630514371574 -2.4600000000000017e-11 3.1939825148020865e-10 -1298.3668759358063 -1.9993727377251318e-11 2.6917015779205735e-10 -1346.2730220995052 -3.6039999999999903e-10 7.588326596826692e-10 -210.55290224269464 -2.4560000000000187e-10 5.258668531001534e-10 -214.1151682003865 -3.800000000000001e-12 1.8382687089675016e-10 -4837.549234125003 +r_4295 2-Propyn-1-al:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4296 D-Glucuronolactone:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4297 4-Trimethylammoniobutanal:NAD+ 1-oxidoreductase; 4-Trimethylammoniobutanal:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4298 (S)-Methylmalonate semialdehyde:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4299 Imidazole acetaldehyde:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4300 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4301 5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4302 N4-Acetylaminobutanal:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4303 Fatty aldehyde dehydrogenase HFD1 (EC 1.2.1.3) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4304 Fatty aldehyde dehydrogenase HFD1 (EC 1.2.1.3) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4305 Chloroacetaldehyde:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4306 Aldehyde:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4307 farnesal:NAD+ oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4309 Putative esterase YMR210W (EC 3.1.1.-) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4310 GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4311 GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4312 S-adenosyl-L-methionine:carnosine N-methyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4313 Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.259) (EC 2.4.1.261) (Asparagine-linked glycosylation protein 9) (Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) (Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4314 Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.259) (EC 2.4.1.261) (Asparagine-linked glycosylation protein 9) (Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) (Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) 1.579573856850561e-10 9.128782645756975e-10 577.9269266939143 8.821919688173764e-11 6.028774763681222e-10 683.3858136073383 5.208783998161666e-11 5.85100310038924e-10 1123.295399166914 1.5753969424551131e-10 6.100606602630998e-10 387.24250620442086 3.4593537172133856e-10 3.6405159741848407e-10 105.23688156172092 3.6156750559720706e-10 5.638839504317874e-10 155.9553725660194 1.8112647738236447e-10 6.21564563715388e-10 343.1660421481299 -1.4895703140301772e-10 5.586302304298335e-10 -375.0277681879987 5.116143902814866e-11 5.459476258799923e-10 1067.1076424953878 +r_4315 Glycolate:NAD+ oxidoreductase 9.843999999999634e-10 1.5543960979898095e-10 15.790289496036843 9.907999999999615e-10 1.1797518225764695e-10 11.907063207272056 9.86799999999963e-10 1.3201986914539356e-10 13.378584226327373 9.92599999999961e-10 9.458873826138534e-11 9.529391321921125 9.831999999999643e-10 1.3312138919366014e-10 13.539604271121336 9.799999999999654e-10 1.6614909299849138e-10 16.95398908147931 9.799999999999654e-10 1.5876095555331648e-10 16.20009750544103 9.804175140616411e-10 1.5985341514156362e-10 16.30462663598575 9.787999999999654e-10 1.6479074973505404e-10 16.835998133945626 +r_4316 Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (EC 2.4.1.260) (Asparagine-linked glycosylation protein 12) (Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase) (Extracellular mutant protein 39) (Mannosyltransferase ALG12) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4317 sucrose glucohydrolase 4.3599999999999874e-11 2.1096905362710101e-10 483.8739762089487 2.959999999999993e-11 2.1710197293745015e-10 733.4526112751712 1.6529999999999875e-10 3.772987952222912e-10 228.25093479872595 5.6000000000000046e-11 2.4428658413231636e-10 436.2260430934217 1.7419999999999848e-10 3.8766534134915716e-10 222.54037964934588 3.159999999999993e-11 2.1403411438466576e-10 677.3231467869186 1.8699999999999806e-10 4.075097702418491e-10 217.9196632309376 4.268000000000157e-10 4.994913996573568e-10 117.03172438081968 6.260000000000019e-11 2.5356281040357605e-10 405.0524127852641 +r_4318 Isomaltose 6-alpha-D-glucanohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4319 Dextrin 6-alpha-D-glucanohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4320 dolichyl beta-D-glucosyl phosphate:D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-glucosyltransferase 1.579573856850561e-10 9.128782645756975e-10 577.9269266939143 8.821919688173764e-11 6.028774763681222e-10 683.3858136073383 5.208783998161666e-11 5.85100310038924e-10 1123.295399166914 1.5753969424551131e-10 6.100606602630998e-10 387.24250620442086 3.4593537172133856e-10 3.6405159741848407e-10 105.23688156172092 3.6156750559720706e-10 5.638839504317874e-10 155.9553725660194 1.8112647738236447e-10 6.21564563715388e-10 343.1660421481299 -1.4895703140301772e-10 5.586302304298335e-10 -375.0277681879987 5.116143902814866e-11 5.459476258799923e-10 1067.1076424953878 +r_4321 dolichyl beta-D-glucosyl phosphate:D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-glucosyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4322 GPI mannosyltransferase 4 (EC 2.4.1.-) (GPI mannosyltransferase IV) (GPI-MT-IV) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4326 thiosulfate:cyanide sulfurtranserase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4327 Magnesium transporter MRS2, mitochondrial (RNA-splicing protein MRS2) -4.1358070650244176e-11 1.965729901342249e-10 -475.2953584237479 -1.975233756166205e-13 1.3967011834137348e-11 -7071.067811865656 -9.816003675230935e-10 1.8301034901008086e-10 -18.64407910439941 -9.781219423377575e-10 1.439965525938097e-10 -14.7217382987699 -7.605398755573104e-10 4.2719808623184635e-10 -56.17037317324132 -1.6445732501867827e-10 8.611152361588461e-10 -523.6101438844667 -8.905754060954706e-10 2.9726036500166846e-10 -33.378461045195515 -9.132329389037355e-10 1.2957900507717109e-10 -14.189041980102084 -3.8032768248057055e-10 4.858533953627293e-10 -127.7459984489953 +r_4328 UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase 1.5795738568152003e-10 9.128782645624903e-10 577.9269266984908 8.821919687771368e-11 6.028774763450724e-10 683.3858136123819 5.2087839981975145e-11 5.851003100331663e-10 1123.2953991481293 1.5753969426030138e-10 6.100606603830053e-10 387.24250624417726 3.4593537172099155e-10 3.6405159741787103e-10 105.23688156164926 3.6156750555305836e-10 5.63883950377776e-10 155.95537257012404 1.8112647737874083e-10 6.215645637145445e-10 343.1660421545298 -1.4895703145554547e-10 5.58630230247774e-10 -375.0277679335271 5.1161439024158796e-11 5.459476258794381e-10 1067.1076425775234 +r_4329 Putative sulfate transporter YPR003C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4330 Pyridoxine:NADP+ 4-oxidoreductase -6.461794351568912e-05 0.0015296336108134 -2367.196366195143 -0.0001596376648819 0.0031957727017002 -2001.89141081649 -7.739160117489508e-05 0.0019297623927788 -2493.5036405538044 -0.0001991414876358 0.0039869706167244 -2002.0793577753093 -0.0003920851578315 0.0078970835333663 -2014.1245787120783 -0.0002085096578431 0.0053081664980914 -2545.765291162128 -0.0003830463103373 0.0088931899699773 -2321.700987576437 -0.0008948972604447 0.0180236806479029 -2014.0502652724888 -0.0007340213344304 0.0158761292976977 -2162.8975280421523 +r_4331 [1,4-(N-Acetyl-beta-D-glucosaminyl)]n glycanohydrolase -4.2259290395399367e-10 1.301775412774392e-09 -308.0447874524916 -1.406423823824927e-10 6.900402022837375e-10 -490.634608568487 1.0243905913340556e-10 8.200040949032856e-10 800.4799163914627 7.6421043172817e-11 1.016209348083658e-09 1329.750688937369 -1.2736756431824336e-11 2.8420981368404353e-10 -2231.414373080973 3.7147178679393725e-10 8.24983228272468e-10 222.0850297656932 3.9774218037174536e-10 8.43749901217241e-10 212.13488104999053 4.378054232322861e-10 9.15890093143522e-10 209.20026215791728 3.5022982246885714e-10 7.973724339075611e-10 227.67119838244625 +r_4332 Protein PNS1 (pH nine-sensitive protein 1) 0.0001796550308906 0.0019613677028868 1091.7410401275745 0.0003583279676116 0.0051135319382411 1427.0535376636772 0.0003200709531697 0.0034457147008588 1076.547142667955 0.0005348419320261 0.0060808111879555 1136.9361345547247 0.0009274814263573 0.0101553604336774 1094.9394936739557 0.0007400343484608 0.0082386524666287 1113.279739482838 0.0013593227358211 0.0135883964903653 999.6446121499598 0.0024284948266352 0.0277516446571819 1142.7508246180853 0.0022402987864262 0.0246175689895553 1098.8520432502332 +r_4333 Polyphosphate phosphohydrolase -0.0026703363481995 0.0605684587799902 -2268.195870562461 -0.0063716277510545 0.1257950767399444 -1974.3004716357457 -0.0132489585806688 0.2155970300330294 -1627.2752965474644 -0.0207093433310605 0.345849473659751 -1670.0166110097489 -0.0444973826147062 0.6082388526775792 -1366.9092808091546 -0.0226683543682175 0.4460332584691606 -1967.64728142122 -0.0413582795031374 0.7129533362306588 -1723.846699610833 -0.0481868946279331 0.8570495953028621 -1778.59478582387 -0.0441656243423492 0.8116047601741921 -1837.6390513197507 +r_4334 Copper-transporting ATPase (EC 3.6.3.54) (Cu(2+)-ATPase) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4335 Endopolyphosphatase (EC 3.6.1.10) (Deoxyadenosine triphosphate phosphohydrolase) (dATP phosphohydrolase) (EC 3.6.1.-) (Exopolyphosphatase) (EC 3.6.1.11) (Phosphate metabolism protein 5) 0.0001180506157615 0.0029491557107376 2498.212899366609 0.0001343842645831 0.0042478246618544 3160.953907090228 0.0002497990309646 0.0053202013194509 2129.7926172511534 0.0001341995057814 0.0047426246371646 3534.0105088668174 0.0007336471376204 0.0156265310263048 2129.9791446047348 0.0005997118387634 0.0127733117480268 2129.908219648437 0.0008054079368681 0.0201197791160177 2498.085528465764 0.002132728250491 0.0402533099683696 1887.409235522672 0.001464334836448 0.0327135783443693 2234.023088853187 +r_4336 Monoamide of a dicarboxylic acid amidohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4337 Iron-sulfur clusters transporter ATM1, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4338 Oligo-1,6-glucosidase IMA2 (EC 3.2.1.10) (Alpha-glucosidase) (Isomaltase 2) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4339 UDP-N-acetylglucosamine transporter YEA4 3.1591477133733945e-10 1.8257565292784559e-09 577.9269267940878 1.7643839372599464e-10 1.205754952678895e-09 683.3858137200051 1.0417567999139795e-10 1.1702006200317815e-09 1123.295398819003 3.15079388546794e-10 1.2201213207716175e-09 387.2425062137669 6.918707434230062e-10 7.281031948318551e-10 105.23688156397397 7.23135011084929e-10 1.127767900822993e-09 155.95537258401964 3.622529547989031e-10 1.2431291274846927e-09 343.1660421306402 -2.9791406286304555e-10 1.1172604604815578e-09 -375.0277679893128 1.0232287805088264e-10 1.0918952517630334e-09 1067.107642554836 +r_4341 glycerol 2-phosphate(2-) transport 9.847999999999638e-10 1.3628160013334848e-10 13.838505293801123 9.89599999999962e-10 1.1087965935992088e-10 11.204492659652905 9.877999999999626e-10 1.2511710857501438e-10 12.666238972972174 9.89399999999962e-10 1.1175928609116152e-10 11.295662633026662 9.89399999999962e-10 1.1528355502677684e-10 11.651865274588769 9.89399999999962e-10 1.17005889063819e-10 11.825943911847936 9.88599999999962e-10 1.1862906292689429e-10 11.999702905816184 9.878978260069983e-10 1.2046985345670912e-10 12.194566106460458 9.833333333332975e-10 1.4949553246599264e-10 15.202935505016754 +r_4342 Glycerol-2-phosphate phosphohydrolase 9.847999999999638e-10 1.3628160013334848e-10 13.838505293801123 9.89599999999962e-10 1.1087965935992088e-10 11.204492659652905 9.877999999999626e-10 1.2511710857501438e-10 12.666238972972174 9.89399999999962e-10 1.1175928609116152e-10 11.295662633026662 9.89399999999962e-10 1.1528355502677684e-10 11.651865274588769 9.89399999999962e-10 1.17005889063819e-10 11.825943911847936 9.88599999999962e-10 1.1862906292689429e-10 11.999702905816184 9.878978260069983e-10 1.2046985345670912e-10 12.194566106460458 9.833333333332975e-10 1.4949553246599264e-10 15.202935505016754 +r_4343 L-Threonine phosphate transport in via proton symport 9.98199999999959e-10 4.239244536335352e-11 4.246888936421084 9.989999999999588e-10 3.16101224288684e-11 3.164176419306276 9.957999999999599e-10 6.4677636315256e-11 6.495042811333462 9.975999999999592e-10 4.8935865618057365e-11 4.905359424424556 1.0128651879937135e-09 1.222688456904982e-09 120.71581404894434 9.959999999999598e-10 6.312524819271773e-11 6.33787632457031 9.967999999999596e-10 5.6483608946456526e-11 5.6664936744039744 9.9559999999996e-10 6.619302307087072e-11 6.648555953281778 9.931999999999608e-10 8.218948243056815e-11 8.27521973727058 +r_4344 acid phosphatase / phosphotransferase 9.98199999999959e-10 4.239244536335352e-11 4.246888936421084 9.989999999999588e-10 3.16101224288684e-11 3.164176419306276 9.957999999999599e-10 6.4677636315256e-11 6.495042811333462 9.975999999999592e-10 4.8935865618057365e-11 4.905359424424556 1.0128651879937135e-09 1.222688456904982e-09 120.71581404894434 9.959999999999598e-10 6.312524819271773e-11 6.33787632457031 9.967999999999596e-10 5.6483608946456526e-11 5.6664936744039744 9.9559999999996e-10 6.619302307087072e-11 6.648555953281778 9.931999999999608e-10 8.218948243056815e-11 8.27521973727058 +r_4345 alkaline phosphatase 1.0207999999999547e-09 1.5611609285045646e-10 15.293504393658248 1.010799999999957e-09 1.1612948467741631e-10 11.488868685934037 1.0177999999999555e-09 1.5584613438748036e-10 15.312058792246727 1.0171999999999555e-09 1.4320705866795818e-10 14.078554725517542 1.023399999999956e-09 1.80163625036676e-10 17.604419096803184 1.0207999999999547e-09 1.5991395966238164e-10 15.665552474763786 1.027251589241363e-09 1.9487194427387007e-10 18.97022563068364 1.0261940907289322e-09 2.106984438182391e-10 20.532026613851823 1.0359646114485263e-09 2.2495785847630932e-10 21.714820756450788 +r_4346 Guanosine transport via proton symport 3.81999999999999e-11 1.9786002556843612e-10 517.9581821163264 1.2879999999999988e-10 3.373919481335238e-10 261.9502702900032 3.279999999999992e-11 1.8582536482741763e-10 566.5407464250551 3.4399999999999915e-11 1.8661083762992427e-10 542.4733652032696 4.199999999999988e-11 2.0553454427365942e-10 489.3679625563334 3.639999999999991e-11 1.915264380582928e-10 526.1715331271794 3.959999999999989e-11 2.040592267789039e-10 515.3010777245062 3.899409072897641e-11 2.134193940658336e-10 547.3121441635315 5.1999999999999956e-11 2.2384374283022304e-10 430.4687362119678 +r_4347 Guanosine 3'-phosphate phosphohydrolase 9.96999999999959e-10 5.4695505479554e-11 5.486008573676653 9.98199999999959e-10 4.239244536335445e-11 4.246888936421177 9.961999999999598e-10 6.153305829757593e-11 6.176777584579242 9.979999999999591e-10 4.468108413921696e-11 4.477062538999879 9.947999999999602e-10 7.193048588018595e-11 7.230647957397348 9.97199999999959e-10 5.28461781372034e-11 5.2994562913362975 9.937999999999603e-10 7.850345571063699e-11 7.899321363517821 9.945999999999604e-10 7.329334473795642e-11 7.369127763720022 9.929999999999611e-10 8.338099590491582e-11 8.39687773463435 +r_4348 Guanosine transport via proton symport(for 3'-GMP) 9.96999999999959e-10 5.4695505479554e-11 5.486008573676653 9.98199999999959e-10 4.239244536335445e-11 4.246888936421177 9.961999999999598e-10 6.153305829757593e-11 6.176777584579242 9.979999999999591e-10 4.468108413921696e-11 4.477062538999879 9.947999999999602e-10 7.193048588018595e-11 7.230647957397348 9.97199999999959e-10 5.28461781372034e-11 5.2994562913362975 9.937999999999603e-10 7.850345571063699e-11 7.899321363517821 9.945999999999604e-10 7.329334473795642e-11 7.369127763720022 9.929999999999611e-10 8.338099590491582e-11 8.39687773463435 +r_4349 2-Phosphoglycolate transport in/out via proton symport 9.843999999999634e-10 1.5543960979898095e-10 15.790289496036843 9.907999999999615e-10 1.1797518225764695e-10 11.907063207272056 9.86799999999963e-10 1.3201986914539356e-10 13.378584226327373 9.92599999999961e-10 9.458873826138534e-11 9.529391321921125 9.831999999999643e-10 1.3312138919366014e-10 13.539604271121336 9.799999999999654e-10 1.6614909299849138e-10 16.95398908147931 9.799999999999654e-10 1.5876095555331648e-10 16.20009750544103 9.804175140616411e-10 1.5985341514156362e-10 16.30462663598575 9.787999999999654e-10 1.6479074973505404e-10 16.835998133945626 +r_4350 2-phosphoglycolate phosphohydrolase 9.843999999999634e-10 1.5543960979898095e-10 15.790289496036843 9.907999999999615e-10 1.1797518225764695e-10 11.907063207272056 9.86799999999963e-10 1.3201986914539356e-10 13.378584226327373 9.92599999999961e-10 9.458873826138534e-11 9.529391321921125 9.831999999999643e-10 1.3312138919366014e-10 13.539604271121336 9.799999999999654e-10 1.6614909299849138e-10 16.95398908147931 9.799999999999654e-10 1.5876095555331648e-10 16.20009750544103 9.804175140616411e-10 1.5985341514156362e-10 16.30462663598575 9.787999999999654e-10 1.6479074973505404e-10 16.835998133945626 +r_4351 alkaline phosphatase 1.0779212996233322e-10 4.6178357080416086e-10 428.40193524845097 1.0577999999999551e-09 3.0931908389093596e-10 29.24173604565599 2.686000000000034e-10 4.838397050387886e-10 180.13391848055934 1.0685707670773404e-09 9.489552198939352e-10 88.80602475111995 2.2628366301326456e-10 5.387045465067652e-10 238.06603593613693 1.3407491297424526e-10 9.32183004226125e-10 695.2702661124902 2.59200000000003e-10 4.703824103029017e-10 181.4746953329076 1.6966799949982604e-10 1.6134897572686134e-09 950.9688108689394 2.3180000000000108e-10 4.5266957258952504e-10 195.28454382636883 +r_4352 cysteamine S-phosphate transport via proton symport 1.0779212996233322e-10 4.6178357080416086e-10 428.40193524845097 1.0577999999999551e-09 3.0931908389093596e-10 29.24173604565599 2.686000000000034e-10 4.838397050387886e-10 180.13391848055934 1.0685707670773404e-09 9.489552198939352e-10 88.80602475111995 2.2628366301326456e-10 5.387045465067652e-10 238.06603593613693 1.3407491297424526e-10 9.32183004226125e-10 695.2702661124902 2.59200000000003e-10 4.703824103029017e-10 181.4746953329076 1.6966799949982604e-10 1.6134897572686134e-09 950.9688108689394 2.3180000000000108e-10 4.5266957258952504e-10 195.28454382636883 +r_4353 Cysteamine:oxygen oxidoreductase 5.4392129962332936e-11 3.9203672722139717e-10 720.7600207840478 9.785999999999658e-10 1.4746657003488356e-10 15.06913652512658 1.6739999999999872e-10 3.7868974264459107e-10 226.21848425602985 9.53770767077359e-10 8.927822390192965e-10 93.60553602990478 1.6748366301326263e-10 4.784807785593696e-10 285.68803067167204 5.4874912974245925e-11 8.773598535759297e-10 1598.8359817312062 1.90599999999998e-10 3.9332248920712254e-10 206.3601727214726 1.1626799949982703e-10 1.5971248137986602e-09 1373.6581180284577 1.6919999999999862e-10 3.7656303581736727e-10 222.5549857076656 +r_4354 hypotaurine:NAD+ oxidoreductase 5.4392129962332936e-11 3.9203672722139717e-10 720.7600207840478 9.785999999999658e-10 1.4746657003488356e-10 15.06913652512658 1.6739999999999872e-10 3.7868974264459107e-10 226.21848425602985 9.53770767077359e-10 8.927822390192965e-10 93.60553602990478 1.6748366301326263e-10 4.784807785593696e-10 285.68803067167204 5.4874912974245925e-11 8.773598535759297e-10 1598.8359817312062 1.90599999999998e-10 3.9332248920712254e-10 206.3601727214726 1.1626799949982703e-10 1.5971248137986602e-09 1373.6581180284577 1.6919999999999862e-10 3.7656303581736727e-10 222.5549857076656 +r_4355 2-aminobutanoate:2-oxoglutarate aminotransferase -9.979999999999591e-10 5.997265496765066e-11 -6.009284064895104 -9.899999999999614e-10 1.3821657195921188e-10 -13.961269894870428 -9.871999999999624e-10 1.5697480121868058e-10 -15.901013089413135 -9.86999999999963e-10 1.5885857612807875e-10 -16.095093832632696 -9.91599999999961e-10 1.262245084177638e-10 -12.729377613732224 -9.929999999999611e-10 1.1555808381132851e-10 -11.637269265995275 -9.887999999999623e-10 1.4240300461418046e-10 -14.401598363085144 -9.89399999999962e-10 1.4032668426091228e-10 -14.183008314222526 -9.92199999999961e-10 1.1892009248936107e-10 -11.985496118662136 +r_4356 2-aminobutyrate transport 9.979999999999591e-10 5.997265496765066e-11 6.009284064895104 9.899999999999614e-10 1.3821657195921188e-10 13.961269894870428 9.871999999999624e-10 1.5697480121868058e-10 15.901013089413135 9.86999999999963e-10 1.5885857612807875e-10 16.095093832632696 9.91599999999961e-10 1.262245084177638e-10 12.729377613732224 9.929999999999611e-10 1.1555808381132851e-10 11.637269265995275 9.887999999999623e-10 1.4240300461418046e-10 14.401598363085144 9.89399999999962e-10 1.4032668426091228e-10 14.183008314222526 9.92199999999961e-10 1.1892009248936107e-10 11.985496118662136 +r_4357 alkaline phosphatase 1.3414626218051508e-10 3.6639048047505617e-10 273.1276105047337 1.505145317384558e-10 4.2354763828514725e-10 281.3998312276799 1.1653854958629838e-10 4.2843126007625687e-10 367.63050646944737 1.2845481963692936e-10 4.250102474945602e-10 330.86360534842424 1.7296983614802643e-10 5.225016682052634e-10 302.07675502340777 1.1196270707855556e-10 3.8847173496043365e-10 346.9652932631159 1.1200336971090174e-10 4.3938899565365517e-10 392.2998002540344 1.5125595221420643e-10 5.028016224008193e-10 332.41774293203287 1.2502014129013447e-10 4.684119062820383e-10 374.66915446447456 +r_4358 Uridine 2'-phosphate transport in via proton symport 1.5654626218051433e-10 3.8383992738924225e-10 245.1926491522579 1.8507663824327447e-10 4.193079614678973e-10 226.5590975975784 1.4531729095579036e-10 3.976592285072572e-10 273.6489414932986 1.6348168336168478e-10 3.9344271066809286e-10 240.66470480221645 2.0298077219163395e-10 4.244341273544049e-10 209.1006565654885 2.189542356706696e-10 4.2692721469158767e-10 194.98467950797337 2.2605726425373692e-10 4.49012995360922e-10 198.62798784334987 2.1155884348535686e-10 4.262569583422993e-10 201.48387622085053 1.5424070040359224e-10 4.1537821156092327e-10 269.3051901826356 +r_4359 Uridine 3'-monophosphate phosphohydrolase 1.2694766591614288e-10 3.797820863592739e-10 299.1642923235346 1.2011365659561732e-10 4.1355555146885614e-10 344.30352317152415 1.1901409783803696e-10 3.691230059412273e-10 310.1506566420029 1.240532471588931e-10 3.9841474231915397e-10 321.1642995598866 1.2859208212427884e-10 4.598475709363866e-10 357.60177713894035 9.823690647512016e-11 5.647028832525162e-10 574.8378114853759 1.0722066807942503e-10 3.5807485364541947e-10 333.9606626776203 1.4715824491764978e-10 4.5896544046153077e-10 311.88564440841844 1.2437884849000949e-10 3.7973123144568805e-10 305.3020960201198 +r_4360 3'-UMP transport in via proton symport 1.2694766591614288e-10 3.797820863592739e-10 299.1642923235346 1.2011365659561732e-10 4.1355555146885614e-10 344.30352317152415 1.1901409783803696e-10 3.691230059412273e-10 310.1506566420029 1.240532471588931e-10 3.9841474231915397e-10 321.1642995598866 1.2859208212427884e-10 4.598475709363866e-10 357.60177713894035 9.823690647512016e-11 5.647028832525162e-10 574.8378114853759 1.0722066807942503e-10 3.5807485364541947e-10 333.9606626776203 1.4715824491764978e-10 4.5896544046153077e-10 311.88564440841844 1.2437884849000949e-10 3.7973123144568805e-10 305.3020960201198 +r_4361 Gly-Met transport via proton symport 3.37800000000009e-10 5.123901528461726e-10 151.68447390354032 2.538000000000028e-10 4.3752010784528935e-10 172.38774934802387 1.4189999999999943e-10 4.374387506064305e-10 308.2725515196845 1.5512415352347891e-10 8.40144493282288e-10 541.5948929933257 2.0319999999999892e-10 4.0637764278774366e-10 199.98899743491424 1.3439999999999969e-10 5.381399064479426e-10 400.4017161071011 1.3999999999999962e-10 5.437454660283333e-10 388.38961859166784 2.4960000000000243e-10 4.77226769028957e-10 191.1966222071123 1.5299999999999916e-10 4.808713418883432e-10 314.2949946982653 +r_4362 dipeptidase 3.37800000000009e-10 5.123901528461726e-10 151.68447390354032 2.538000000000028e-10 4.3752010784528935e-10 172.38774934802387 1.4189999999999943e-10 4.374387506064305e-10 308.2725515196845 1.5512415352347891e-10 8.40144493282288e-10 541.5948929933257 2.0319999999999892e-10 4.0637764278774366e-10 199.98899743491424 1.3439999999999969e-10 5.381399064479426e-10 400.4017161071011 1.3999999999999962e-10 5.437454660283333e-10 388.38961859166784 2.4960000000000243e-10 4.77226769028957e-10 191.1966222071123 1.5299999999999916e-10 4.808713418883432e-10 314.2949946982653 +r_4363 R07420 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4364 N-phosphocreatine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4365 creatinine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4366 ATP:L-arginine Nomega-phosphotransferase 9.987999999999587e-10 3.998599474760312e-11 4.003403559031314 9.979999999999591e-10 5.6538830266158864e-11 5.665213453523164 9.987999999999587e-10 3.998599474760104e-11 4.003403559031106 9.98199999999959e-10 5.096351102398083e-11 5.1055410763356965 9.991999999999587e-10 3.463524101235226e-11 3.466297138946526 9.985999999999587e-10 4.6887948301661096e-11 4.695368345850494 9.97199999999959e-10 5.994062541979014e-11 6.010893042498253 9.967999999999596e-10 5.99205982581892e-11 6.011295972932547 9.973999999999594e-10 5.82573496115051e-11 5.84092135667811 +r_4367 L-arginine phosphate transport in/out via proton symport 9.987999999999587e-10 3.998599474760312e-11 4.003403559031314 9.979999999999591e-10 5.6538830266158864e-11 5.665213453523164 9.987999999999587e-10 3.998599474760104e-11 4.003403559031106 9.98199999999959e-10 5.096351102398083e-11 5.1055410763356965 9.991999999999587e-10 3.463524101235226e-11 3.466297138946526 9.985999999999587e-10 4.6887948301661096e-11 4.695368345850494 9.97199999999959e-10 5.994062541979014e-11 6.010893042498253 9.967999999999596e-10 5.99205982581892e-11 6.011295972932547 9.973999999999594e-10 5.82573496115051e-11 5.84092135667811 +r_4368 acid phosphatase / phosphotransferase 9.91399999999961e-10 9.448717143142971e-11 9.530680999741111 9.939999999999606e-10 7.723466215766028e-11 7.770086736183435 9.871999999999624e-10 1.1242191840361123e-10 11.387957698907565 9.89599999999962e-10 1.0145885264360168e-10 10.252511382741064 9.85999999999963e-10 1.175021759469603e-10 11.917056384073495 9.92199999999961e-10 8.798129427115769e-11 8.867294322834223 9.86799999999963e-10 1.1414186643442392e-10 11.566869318446312 9.871796767822754e-10 1.2978561367292435e-10 13.147111587220092 9.848837359253126e-10 1.2532869978939844e-10 12.725227884045651 +r_4369 Tripolyphosphate transport in via proton symport 9.89199999999962e-10 1.0337067814142655e-10 10.44992702602411 9.911999999999614e-10 9.340398739332839e-11 9.423323990449155 9.933999999999606e-10 8.097994535877968e-11 8.151796392065924 9.917410333546136e-10 2.0221396013238664e-10 20.38979464713564 9.917999999999614e-10 9.019083588355848e-11 9.09365153090966 9.861957919916156e-10 4.744810716839918e-10 48.11225879658039 9.874622938992356e-10 4.00257156555868e-10 40.53391800666687 9.907999999999615e-10 9.548394334487688e-11 9.637055242721091 9.927999999999604e-10 8.455524772587452e-11 8.51684606425039 +r_4370 alkaline phosphatase 9.517258090221556e-10 2.520812869168637e-10 26.486755379247622 8.90558595665875e-10 3.6075299540052806e-10 40.50861977597233 9.769389740893286e-10 2.27792752636185e-10 23.31698894995219 9.537984581632884e-10 3.92044962908826e-10 41.10354336950592 9.45217398162529e-10 3.2613921783198816e-10 34.504148830310555 9.295155509010667e-10 3.171373345476513e-10 34.11856146357317 8.743786321218082e-10 3.892779647540371e-10 44.52052582865583 9.66999999999974e-10 3.180113618178435e-10 32.88638695117394 7.68537798996669e-10 4.4927193641781903e-10 58.45801429732492 +r_4371 Cytidine- 2'- Monophosphate transport in via proton symport 9.84199999999964e-10 1.2630736601696182e-10 12.833505996440405 9.243999999999847e-10 2.6513901964807457e-10 28.682282523591407 9.805999999999652e-10 1.4222406806553116e-10 14.503780141294738 9.82999999999964e-10 1.2928396214757067e-10 13.151979872591593 9.727554932992124e-10 1.6297842458920267e-10 16.75430524030685 9.81199999999965e-10 1.4160003571334622e-10 14.431312241474858 9.677786321217748e-10 1.779209629856534e-10 18.384469038707373 9.759999999999664e-10 1.5436568839334196e-10 15.816156597679017 9.847999999999638e-10 1.2558707904431954e-10 12.752546612949246 +r_4372 cyclic phosphodiesterase -2.239999999999997e-11 1.7973508544573203e-10 -802.3887743113048 -3.456210650481987e-11 2.5929576720514856e-10 -750.2313759984172 -2.877874136949285e-11 2.673304961092192e-10 -928.9165661449152 -3.502686372475657e-11 2.9195430376530385e-10 -833.515401377355 -3.0010936043608166e-11 3.80886121367418e-10 -1269.1577524071945 -1.06991528592115e-10 3.7438288178311976e-10 -349.91824746273494 -1.1405389454283527e-10 4.1128173307132405e-10 -360.60297170900975 -6.030289127115016e-11 3.9346664075299007e-10 -652.4838734245411 -2.922055911345865e-11 3.10268489337119e-10 -1061.815717257145 +r_4373 2',3'-Cyclic UMP transport in via proton symport -2.239999999999997e-11 1.7973508544573203e-10 -802.3887743113048 -3.456210650481987e-11 2.5929576720514856e-10 -750.2313759984172 -2.877874136949285e-11 2.673304961092192e-10 -928.9165661449152 -3.502686372475657e-11 2.9195430376530385e-10 -833.515401377355 -3.0010936043608166e-11 3.80886121367418e-10 -1269.1577524071945 -1.06991528592115e-10 3.7438288178311976e-10 -349.91824746273494 -1.1405389454283527e-10 4.1128173307132405e-10 -360.60297170900975 -6.030289127115016e-11 3.9346664075299007e-10 -652.4838734245411 -2.922055911345865e-11 3.10268489337119e-10 -1061.815717257145 +r_4374 3-Sulfino-L-alanine 4-carboxy-lyase 1.1506084615745578e-10 5.50499430750597e-10 478.4420149294421 8.162000000000225e-10 3.8735974173098165e-10 47.45892449534072 6.939599999793465e-11 2.541597816793609e-10 366.24557854476495 1.4739999999999928e-10 3.5453967292240726e-10 240.52895042225845 8.020000000000059e-11 2.7162974163980264e-10 338.6904509224447 1.0380000000000068e-10 3.0568652055622655e-10 294.49568454356904 1.3419600000036264e-10 3.4148914558328925e-10 254.47043546928856 8.020000000000059e-11 2.7236518969814984e-10 339.6074684515559 7.559599997191394e-11 2.6438476629771155e-10 349.73380389959533 +r_4375 3-Sulfino-L-alanine transport via proton antiport 1.1506084615745578e-10 5.50499430750597e-10 478.4420149294421 8.162000000000225e-10 3.8735974173098165e-10 47.45892449534072 6.939599999793465e-11 2.541597816793609e-10 366.24557854476495 1.4739999999999928e-10 3.5453967292240726e-10 240.52895042225845 8.020000000000059e-11 2.7162974163980264e-10 338.6904509224447 1.0380000000000068e-10 3.0568652055622655e-10 294.49568454356904 1.3419600000036264e-10 3.4148914558328925e-10 254.47043546928856 8.020000000000059e-11 2.7236518969814984e-10 339.6074684515559 7.559599997191394e-11 2.6438476629771155e-10 349.73380389959533 +r_4376 adenosine 3'-phosphate phosphohydrolase 9.9559999999996e-10 7.734233231079549e-11 7.768414253796564 9.9559999999996e-10 6.619302307087069e-11 6.648555953281776 9.9539999999996e-10 7.334791055781481e-11 7.368687016055632 9.979999999999591e-10 4.468108413921793e-11 4.477062538999975 9.961999999999598e-10 7.607047616170677e-11 7.6360646618861505 9.967999999999596e-10 5.6483608946455285e-11 5.666493674403849 9.929999999999611e-10 9.461918705057958e-11 9.528619038326616 9.927999999999604e-10 9.354095350164462e-11 9.42193326970672 9.92599999999961e-10 1.0073365601371979e-10 10.148464236724136 +r_4377 3AMP transport via diffusion (extracellular to periplasm) 9.9559999999996e-10 7.734233231079549e-11 7.768414253796564 9.9559999999996e-10 6.619302307087069e-11 6.648555953281776 9.9539999999996e-10 7.334791055781481e-11 7.368687016055632 9.979999999999591e-10 4.468108413921793e-11 4.477062538999975 9.961999999999598e-10 7.607047616170677e-11 7.6360646618861505 9.967999999999596e-10 5.6483608946455285e-11 5.666493674403849 9.929999999999611e-10 9.461918705057958e-11 9.528619038326616 9.927999999999604e-10 9.354095350164462e-11 9.42193326970672 9.92599999999961e-10 1.0073365601371979e-10 10.148464236724136 +r_4378 alpha-glucosidase 2.9000000000000536e-10 4.542480250410136e-10 156.63725001413968 8.330000000000166e-10 3.7301317371581804e-10 44.77949264295447 1.3509999999999972e-10 3.449953541120121e-10 255.3629564115565 2.430000000000019e-10 4.29404095899784e-10 176.70950448550644 8.620000000000072e-11 2.828171796610214e-10 328.0941759408573 2.4640000000000217e-10 4.309572888778726e-10 174.90149710952468 1.0660000000000058e-10 3.112166627323153e-10 291.948088867086 1.2220000000000008e-10 3.2754941264418486e-10 268.04370920146044 1.4839999999999928e-10 3.5553160273609365e-10 239.5765517089591 +r_4379 Palatinose transport in via proton symport 2.9000000000000536e-10 4.542480250410136e-10 156.63725001413968 8.330000000000166e-10 3.7301317371581804e-10 44.77949264295447 1.3509999999999972e-10 3.449953541120121e-10 255.3629564115565 2.430000000000019e-10 4.29404095899784e-10 176.70950448550644 8.620000000000072e-11 2.828171796610214e-10 328.0941759408573 2.4640000000000217e-10 4.309572888778726e-10 174.90149710952468 1.0660000000000058e-10 3.112166627323153e-10 291.948088867086 1.2220000000000008e-10 3.2754941264418486e-10 268.04370920146044 1.4839999999999928e-10 3.5553160273609365e-10 239.5765517089591 +r_4380 Amino-Acid N-Acetyltransferase 9.63999999999971e-10 2.590703060651527e-10 26.874513077298808 8.75127751983169e-10 7.343742481523357e-10 83.91623354283249 -1.0082464972548255e-10 8.647089803454582e-10 -857.6364834391393 7.375923140577744e-10 6.318404436217813e-10 85.66255797132538 -7.298857607385357e-11 9.162850664894271e-10 -1255.3814799213003 9.46399999999977e-10 3.167761187682601e-10 33.47169471346871 3.5155130379251025e-11 8.974470258286607e-10 2552.819506419309 2.0399094289570875e-10 8.672383163897261e-10 425.1356967515492 7.000000000000035e-11 8.121772752209293e-10 1160.2532503156078 +r_4381 Acetylcysteine transport via proton symport 9.63999999999971e-10 2.590703060651527e-10 26.874513077298808 8.75127751983169e-10 7.343742481523357e-10 83.91623354283249 -1.0082464972548255e-10 8.647089803454582e-10 -857.6364834391393 7.375923140577744e-10 6.318404436217813e-10 85.66255797132538 -7.298857607385357e-11 9.162850664894271e-10 -1255.3814799213003 9.46399999999977e-10 3.167761187682601e-10 33.47169471346871 3.5155130379251025e-11 8.974470258286607e-10 2552.819506419309 2.0399094289570875e-10 8.672383163897261e-10 425.1356967515492 7.000000000000035e-11 8.121772752209293e-10 1160.2532503156078 +r_4382 thiosulfate:ferricytochrome-c oxidoreductase 9.719999999999681e-10 2.1914745063775512e-10 22.54603401623069 9.86599999999963e-10 1.3573549581802983e-10 13.75790551571406 9.707999999999686e-10 2.0483103073077144e-10 21.09919970444768 9.793999999999654e-10 1.5159233505428562e-10 15.478081994516128 9.845999999999635e-10 1.684295511563727e-10 17.106393576719366 9.68999999999969e-10 2.237163601571364e-10 23.08734366946785 9.86999999999963e-10 1.5243243463720068e-10 15.4440156673968 3.628000000000109e-10 4.82517071765247e-10 132.9980903432284 9.823999999999643e-10 1.78035331650388e-10 18.122488970927776 +r_4383 etrathionate transport via diffusion -9.719999999999681e-10 2.1914745063775512e-10 -22.54603401623069 -9.86599999999963e-10 1.3573549581802983e-10 -13.75790551571406 -9.707999999999686e-10 2.0483103073077144e-10 -21.09919970444768 -9.793999999999654e-10 1.5159233505428562e-10 -15.478081994516128 -9.845999999999635e-10 1.684295511563727e-10 -17.106393576719366 -9.68999999999969e-10 2.237163601571364e-10 -23.08734366946785 -9.86999999999963e-10 1.5243243463720068e-10 -15.4440156673968 -3.628000000000109e-10 4.82517071765247e-10 -132.9980903432284 -9.823999999999643e-10 1.78035331650388e-10 -18.122488970927776 +r_4384 D-Gluconate:NADP+ 5-oxidoreductase 8.028000000000272e-10 4.1658956944923105e-10 51.892073922423634 8.02600000000027e-10 4.0157875080561926e-10 50.03473097503185 1.9199999999999983e-11 1.401259685333539e-10 729.8227527778855 7.040000000000037e-11 2.665671615377919e-10 378.6465362752706 1.699999999999999e-11 1.411204556278101e-10 830.1203272224129 7.590000000000405e-10 4.5360792765383917e-10 59.76389033647099 1.8599999999999983e-11 1.3805017772648768e-10 742.2052565940205 2.1399999999999973e-11 2.1012108455372054e-10 981.874226886546 1.4400000000000002e-11 1.1914478207550577e-10 827.3943199687899 +r_4385 5-Dehydro-D-gluconate transport via proton symport 8.028000000000272e-10 4.1658956944923105e-10 51.892073922423634 8.02600000000027e-10 4.0157875080561926e-10 50.03473097503185 1.9199999999999983e-11 1.401259685333539e-10 729.8227527778855 7.040000000000037e-11 2.665671615377919e-10 378.6465362752706 1.699999999999999e-11 1.411204556278101e-10 830.1203272224129 7.590000000000405e-10 4.5360792765383917e-10 59.76389033647099 1.8599999999999983e-11 1.3805017772648768e-10 742.2052565940205 2.1399999999999973e-11 2.1012108455372054e-10 981.874226886546 1.4400000000000002e-11 1.1914478207550577e-10 827.3943199687899 +r_4386 dipeptidase 8.040000000000057e-11 2.7704005168577157e-10 344.5771787136438 9.940000000000079e-11 3.0714574342085755e-10 308.9997418720876 1.3599999999999966e-10 3.4860910151793264e-10 256.3302217043629 1.5159999999999915e-10 3.631030277507208e-10 239.51387054797016 2.5640000000000286e-10 4.493321932423475e-10 175.24656522712266 1.4179999999999947e-10 3.573769769595188e-10 252.02889771475324 1.5979999999999895e-10 3.7508945389025697e-10 234.72431407400464 2.2700000000000072e-10 4.2744302720747887e-10 188.30089304294168 3.3540000000000884e-10 4.759749472714865e-10 141.91262590085694 +r_4387 ala-L-asp-L transport via proton symport 8.040000000000057e-11 2.7704005168577157e-10 344.5771787136438 9.940000000000079e-11 3.0714574342085755e-10 308.9997418720876 1.3599999999999966e-10 3.4860910151793264e-10 256.3302217043629 1.5159999999999915e-10 3.631030277507208e-10 239.51387054797016 2.5640000000000286e-10 4.493321932423475e-10 175.24656522712266 1.4179999999999947e-10 3.573769769595188e-10 252.02889771475324 1.5979999999999895e-10 3.7508945389025697e-10 234.72431407400464 2.2700000000000072e-10 4.2744302720747887e-10 188.30089304294168 3.3540000000000884e-10 4.759749472714865e-10 141.91262590085694 +r_4388 cyclic phosphodiesterase -3.247419097781949e-11 2.3447426291260403e-10 -722.0326537857543 -3.3841404334121894e-11 2.767023460664985e-10 -817.6443960025107 -3.661025910639524e-12 1.9930580415100827e-10 -5443.987806035295 -2.920154183669179e-11 3.8311841701796727e-10 -1311.9800973542376 -2.7538095136696112e-11 3.036966270010106e-10 -1102.8236539001468 -5.1684449098917145e-11 3.0468149871138556e-10 -589.503233609525 -9.340000000000087e-11 3.8510531185669826e-10 -412.3183210457116 -9.000000000000004e-12 3.0089384743043257e-10 -3343.264971449249 -2.1626220100336966e-10 4.4390283244591566e-10 -205.26140508437675 +r_4389 2',3'-Cyclic CMP transport in via proton symport -3.247419097781949e-11 2.3447426291260403e-10 -722.0326537857543 -3.3841404334121894e-11 2.767023460664985e-10 -817.6443960025107 -3.661025910639524e-12 1.9930580415100827e-10 -5443.987806035295 -2.920154183669179e-11 3.8311841701796727e-10 -1311.9800973542376 -2.7538095136696112e-11 3.036966270010106e-10 -1102.8236539001468 -5.1684449098917145e-11 3.0468149871138556e-10 -589.503233609525 -9.340000000000087e-11 3.8510531185669826e-10 -412.3183210457116 -9.000000000000004e-12 3.0089384743043257e-10 -3343.264971449249 -2.1626220100336966e-10 4.4390283244591566e-10 -205.26140508437675 +r_4390 beta-glucosidase (methyl-alpha-D-glucoside) -4.5098198716341053e-10 1.76065515185276e-09 -390.4047616018857 6.790334706893117e-10 1.4298783016201307e-09 210.57552585274024 -2.684000000000038e-10 4.783379573484437e-10 -178.21831495843412 -5.66200000000026e-10 6.914572890906326e-10 -122.12244597149432 -2.7780000000000446e-10 4.777790436623576e-10 -171.9866967827034 -5.454000000000244e-10 8.030366203123906e-10 -147.23810420101844 -2.9520000000000576e-10 4.891879198878491e-10 -165.71406500265564 -2.2540000000000056e-10 4.51038276763111e-10 -200.10571284964948 -3.4820000000000977e-10 5.124541753721596e-10 -147.17236512698028 +r_4391 Methanol diffusion -4.5098198716341053e-10 1.76065515185276e-09 -390.4047616018857 6.790334706893117e-10 1.4298783016201307e-09 210.57552585274024 -2.684000000000038e-10 4.783379573484437e-10 -178.21831495843412 -5.66200000000026e-10 6.914572890906326e-10 -122.12244597149432 -2.7780000000000446e-10 4.777790436623576e-10 -171.9866967827034 -5.454000000000244e-10 8.030366203123906e-10 -147.23810420101844 -2.9520000000000576e-10 4.891879198878491e-10 -165.71406500265564 -2.2540000000000056e-10 4.51038276763111e-10 -200.10571284964948 -3.4820000000000977e-10 5.124541753721596e-10 -147.17236512698028 +r_4392 alpha-Methyl-D-glucoside transport via proton symport -4.5098198716341053e-10 1.76065515185276e-09 -390.4047616018857 6.790334706893117e-10 1.4298783016201307e-09 210.57552585274024 -2.684000000000038e-10 4.783379573484437e-10 -178.21831495843412 -5.66200000000026e-10 6.914572890906326e-10 -122.12244597149432 -2.7780000000000446e-10 4.777790436623576e-10 -171.9866967827034 -5.454000000000244e-10 8.030366203123906e-10 -147.23810420101844 -2.9520000000000576e-10 4.891879198878491e-10 -165.71406500265564 -2.2540000000000056e-10 4.51038276763111e-10 -200.10571284964948 -3.4820000000000977e-10 5.124541753721596e-10 -147.17236512698028 +r_4393 ATP:D-tagatose 6-phosphotransferase 9.973999999999594e-10 5.4715982745025655e-11 5.485861514440335 9.973999999999594e-10 6.778022448890859e-11 6.795691246131078 9.9539999999996e-10 8.354780695632103e-11 8.393390290970904 9.959999999999598e-10 7.473364050683722e-11 7.503377560927735 9.951999999999601e-10 7.468651561776135e-11 7.504673996961851 9.951999999999601e-10 7.986385695124196e-11 8.02490524027785 9.947999999999602e-10 7.729265703135543e-11 7.769667976614246 9.917999999999614e-10 1.0067167902340242e-10 10.150401192115984 9.903999999999618e-10 1.1794330046435025e-10 11.908653116352465 +r_4394 D-tagatose 6-phosphate 4-epimerase 9.973999999999594e-10 5.4715982745025655e-11 5.485861514440335 9.973999999999594e-10 6.778022448890859e-11 6.795691246131078 9.9539999999996e-10 8.354780695632103e-11 8.393390290970904 9.959999999999598e-10 7.473364050683722e-11 7.503377560927735 9.951999999999601e-10 7.468651561776135e-11 7.504673996961851 9.951999999999601e-10 7.986385695124196e-11 8.02490524027785 9.947999999999602e-10 7.729265703135543e-11 7.769667976614246 9.917999999999614e-10 1.0067167902340242e-10 10.150401192115984 9.903999999999618e-10 1.1794330046435025e-10 11.908653116352465 +r_4395 D-tagatose uptake via diffusion 9.973999999999594e-10 5.4715982745025655e-11 5.485861514440335 9.973999999999594e-10 6.778022448890859e-11 6.795691246131078 9.9539999999996e-10 8.354780695632103e-11 8.393390290970904 9.959999999999598e-10 7.473364050683722e-11 7.503377560927735 9.951999999999601e-10 7.468651561776135e-11 7.504673996961851 9.951999999999601e-10 7.986385695124196e-11 8.02490524027785 9.947999999999602e-10 7.729265703135543e-11 7.769667976614246 9.917999999999614e-10 1.0067167902340242e-10 10.150401192115984 9.903999999999618e-10 1.1794330046435025e-10 11.908653116352465 +r_4396 Acetoacetate:CoA ligase (AMP-forming) 2.731389882307747e-05 0.0004676529810069 1712.1429058376564 8.666866933130543e-05 0.0011166506202615 1288.4132511519038 4.823662481517195e-05 0.0007684677918265 1593.1209838397497 6.887845863366373e-05 0.0010897307814621 1582.1068053482234 0.0001474522368334 0.0023270696837099 1578.1854068025614 0.0001267515040575 0.0019518835506491 1539.9293011641478 0.00022684873779 0.0035174237627761 1550.5591069377233 0.0003658476614357 0.0054871424245156 1499.843514915845 0.0003497131130438 0.0052771460407827 1508.9928984507596 +r_4397 N-Acyl-Aliphatic-L-Amino Acid Amidohydrolase 9.96999999999959e-10 6.776369517430939e-11 6.79675979682168 9.989999999999588e-10 3.1610122428867234e-11 3.16417641930616 9.883999999999624e-10 1.4376916886030082e-10 14.545646384086028 9.86799999999963e-10 1.4909797463817632e-10 15.109239424217868 9.86999999999963e-10 1.4434391928102007e-10 14.624510565453445 9.957999999999599e-10 8.113985910356968e-11 8.148208385576716 9.871999999999624e-10 1.4913285393106748e-10 15.106650519760242 9.83599999999964e-10 1.5917319881639408e-10 16.182716431110197 9.823999999999643e-10 1.6029778250435878e-10 16.31695668814786 +r_4398 Ala-Gln transport via proton symport 1.739999999999985e-10 3.822999223726405e-10 219.71259906473784 3.168000000000075e-10 4.661343328304013e-10 147.13836263585557 2.418000000000018e-10 4.3054597195515404e-10 178.0587146216505 3.262000000000081e-10 4.752249233211089e-10 145.6851389702934 2.6598086895961885e-10 4.755229906559694e-10 178.78089973762863 2.4060000000000173e-10 4.335311175059745e-10 180.18749688527487 3.7160000000001136e-10 4.861694274041011e-10 130.83138520023846 3.1499614176468604e-10 4.844282589555752e-10 153.78863253425547 3.040000000000065e-10 4.621977123970709e-10 152.03872118324378 +r_4399 L-alanyl-L-glutamate transport in via proton symport 9.145999999999879e-10 2.865715698615779e-10 31.33299473666976 8.110000000000241e-10 3.956138294605176e-10 48.78099006911292 9.055999999999912e-10 2.951373599059429e-10 32.59025617335974 7.326000000000385e-10 4.4624776460336726e-10 60.91288078123721 8.740000000000074e-11 2.8944428755655145e-10 331.1719537260286 7.676000000000392e-10 4.2335101891578727e-10 55.15255587750983 4.3340000000001615e-10 4.980100830390555e-10 114.90772566659832 8.69522416879099e-10 3.4410567095223234e-10 39.57410002002027 8.796000000000004e-10 3.363427794572889e-10 38.23815137076953 +r_4400 Maltodextrin glucosidase (maltotriose) 9.657999999999703e-10 1.8394870868121526e-10 19.046252710832565 9.52599999988662e-10 2.1900418389940342e-10 22.99015157484884 9.647999999999707e-10 1.8538563473666006e-10 19.214928973535 9.681999999999707e-10 1.9389759992287408e-10 20.026606065160088 2.1459999999999976e-10 4.14464951762196e-10 193.13371470745403 9.84999999999964e-10 1.5224859909760679e-10 15.456710568285514 9.385999999999796e-10 2.442170518077608e-10 26.01928955974495 9.80399999999965e-10 1.4703796799739824e-10 14.997752753713122 9.729999999999676e-10 1.6576035502814612e-10 17.036007711012502 +r_4401 Ala-Thr transport via proton symport 8.716000000000031e-10 3.687012722050703e-10 42.301660418204335 6.608000000000332e-10 6.143442388179176e-10 92.96976979689566 -6.590000000000025e-11 7.1582796252618e-10 -1086.233630540482 3.204000000000076e-10 6.107523587254871e-10 190.6218348081999 -1.8999999999999983e-11 3.5194285438767126e-10 -1852.3308125666929 7.932000000000304e-10 4.800831760968103e-10 60.52485830771456 -8.080000000000059e-11 4.90631739597817e-10 -607.2174995022442 8.180000000000061e-11 6.449743858415526e-10 788.4772443050705 -8.000000000000005e-13 5.158028407387101e-10 -64475.35509233872 +r_4402 Ala-Thr transport via proton symport (extracellular to cytosol) 8.716000000000031e-10 3.687012722050703e-10 42.301660418204335 6.608000000000332e-10 6.143442388179176e-10 92.96976979689566 -6.590000000000025e-11 7.1582796252618e-10 -1086.233630540482 3.204000000000076e-10 6.107523587254871e-10 190.6218348081999 -1.8999999999999983e-11 3.5194285438767126e-10 -1852.3308125666929 7.932000000000304e-10 4.800831760968103e-10 60.52485830771456 -8.080000000000059e-11 4.90631739597817e-10 -607.2174995022442 8.180000000000061e-11 6.449743858415526e-10 788.4772443050705 -8.000000000000005e-13 5.158028407387101e-10 -64475.35509233872 +r_4403 Triphosphate phosphohydrolase 9.89199999999962e-10 1.0337067814142655e-10 10.44992702602411 9.911999999999614e-10 9.340398739332839e-11 9.423323990449155 9.933999999999606e-10 8.097994535877968e-11 8.151796392065924 9.917410333546136e-10 2.0221396013238664e-10 20.38979464713564 9.917999999999614e-10 9.019083588355848e-11 9.09365153090966 9.861957919916156e-10 4.744810716839918e-10 48.11225879658039 9.874622938992356e-10 4.00257156555868e-10 40.53391800666687 9.907999999999615e-10 9.548394334487688e-11 9.637055242721091 9.927999999999604e-10 8.455524772587452e-11 8.51684606425039 +r_4404 Gly-Asn transport via proton symport (extracellular to cytosol) 1.0040000000000076e-10 3.0518595592446975e-10 303.9700756219796 2.600000000000032e-10 4.4456667430833915e-10 170.9871824262822 1.477999999999993e-10 3.588605804253601e-10 242.8014752539661 2.4560000000000213e-10 4.351074622443744e-10 177.1610188291411 1.323999999999998e-10 3.488475009453101e-10 263.47998560824067 2.548000000000028e-10 4.376245686117286e-10 171.75218548340808 2.1559999999999983e-10 4.127356419574556e-10 191.4358265108793 3.032000000000064e-10 4.627230084148827e-10 152.61312942443038 3.4360000000000944e-10 4.778961361461082e-10 139.08502216126166 +r_4405 glycerol 1-phosphate transport 9.813999999999648e-10 1.4648662623711771e-10 14.926291648372016 9.89399999999962e-10 1.0995479985704526e-10 11.113280761779814 9.889999999999622e-10 1.2199170625611024e-10 12.334854019829615 9.881999999999623e-10 1.1858993513171163e-10 12.00060060025462 9.883999999999624e-10 1.1776337988834848e-10 11.914546730913896 9.883999999999624e-10 1.2111306153645962e-10 12.253446128739805 9.871999999999624e-10 1.2585439152279776e-10 12.748621507577235 9.87342624432624e-10 1.3608438173752269e-10 13.78289343233039 9.84100000000012e-10 1.4353156538581938e-10 14.58505897630501 +r_4406 D-O-Phosphoserine transport in/out via proton symport 9.593693553831396e-10 3.812573054171452e-10 39.74040897573635 7.99600000000028e-10 5.179705577537583e-10 64.77870907375438 -3.494000000000099e-10 5.386814230462048e-10 -154.17327505615043 4.1974745808207197e-10 1.3065886944151366e-09 311.27971575700724 -7.840000000000054e-11 3.6644275959447405e-10 -467.40147907458106 9.121999999999892e-10 3.6071759513045404e-10 39.54369602394853 -2.5920000000000315e-10 5.127064789786583e-10 -197.80342553188737 -1.8959999999999803e-10 6.84796049291911e-10 -361.1793508923619 -4.0580000000001415e-10 5.407262125765568e-10 -133.2494363175303 +r_4407 D-O-Phosphoserine phosphohydrolase 9.593693553831396e-10 3.812573054171452e-10 39.74040897573635 7.99600000000028e-10 5.179705577537583e-10 64.77870907375438 -3.494000000000099e-10 5.386814230462048e-10 -154.17327505615043 4.1974745808207197e-10 1.3065886944151366e-09 311.27971575700724 -7.840000000000054e-11 3.6644275959447405e-10 -467.40147907458106 9.121999999999892e-10 3.6071759513045404e-10 39.54369602394853 -2.5920000000000315e-10 5.127064789786583e-10 -197.80342553188737 -1.8959999999999803e-10 6.84796049291911e-10 -361.1793508923619 -4.0580000000001415e-10 5.407262125765568e-10 -133.2494363175303 +r_4408 L-alanyl-L-glutamate transport in via proton symport 9.145999999999879e-10 2.865715698615779e-10 31.33299473666976 8.110000000000241e-10 3.956138294605176e-10 48.78099006911292 9.055999999999912e-10 2.951373599059429e-10 32.59025617335974 7.326000000000385e-10 4.4624776460336726e-10 60.91288078123721 8.740000000000074e-11 2.8944428755655145e-10 331.1719537260286 7.676000000000392e-10 4.2335101891578727e-10 55.15255587750983 4.3340000000001615e-10 4.980100830390555e-10 114.90772566659832 8.69522416879099e-10 3.4410567095223234e-10 39.57410002002027 8.796000000000004e-10 3.363427794572889e-10 38.23815137076953 +r_4409 L-alanyl-gamma-L-glutamate peptidase 9.145999999999879e-10 2.865715698615779e-10 31.33299473666976 8.110000000000241e-10 3.956138294605176e-10 48.78099006911292 9.055999999999912e-10 2.951373599059429e-10 32.59025617335974 7.326000000000385e-10 4.4624776460336726e-10 60.91288078123721 8.740000000000074e-11 2.8944428755655145e-10 331.1719537260286 7.676000000000392e-10 4.2335101891578727e-10 55.15255587750983 4.3340000000001615e-10 4.980100830390555e-10 114.90772566659832 8.69522416879099e-10 3.4410567095223234e-10 39.57410002002027 8.796000000000004e-10 3.363427794572889e-10 38.23815137076953 +r_4410 3-oxalomalate glyoxylate-lyase (oxaloacetate-forming) 9.421999999999786e-10 3.2385202798067844e-10 34.371898533292914 -4.3680000000001647e-10 5.235079484730079e-10 -119.85072080425554 -7.780000000000054e-11 3.4780936484065175e-10 -447.0557388697293 -1.6699999999999867e-10 3.9082163234607775e-10 -234.0249295485514 -1.2160000000000008e-10 3.8163145639960916e-10 -313.8416582233626 8.738000000000022e-10 4.75309103372481e-10 54.39564012044858 -4.3520000000001624e-10 5.417191633405674e-10 -124.47591069405952 -2.2320000000000043e-10 6.93309379410902e-10 -310.6224818149197 -1.8799999999999806e-10 4.4575300239913015e-10 -237.1026608506036 +r_4411 L-cysteate bisulfite-lyase (deaminating) 1.0001761538482852e-10 4.289637595828689e-10 428.8882092743211 9.279599999491794e-11 2.9225684800935285e-10 314.9455235412718 6.520000000000025e-11 2.4690312316868686e-10 378.6857717311133 7.960000000000057e-11 2.7070001052666703e-10 340.0753901088757 7.380000000000045e-11 2.6147128608451693e-10 354.2971356158744 9.617599994521724e-11 2.990259862526905e-10 310.91539097385885 1.2039600000046835e-10 3.2608917493982577e-10 270.84718341021073 7.479999997987767e-11 2.646109669609901e-10 353.7579773157413 6.98000000002109e-11 2.5640028904272855e-10 367.33565765322913 +r_4412 cyclic phosphodiesterase 9.825999999999643e-10 1.3675152721648878e-10 13.91731398498817 8.819999999999993e-10 3.2387803166605356e-10 36.72086526826006 9.849999999999634e-10 1.2481232159976992e-10 12.671301685256298 9.827999999999644e-10 1.3002900256597468e-10 13.230464241552644 9.813999999999648e-10 1.3659345355583708e-10 13.918224328086612 9.843999999999634e-10 1.2868547699876155e-10 13.07247836232896 9.876515892413704e-10 1.1384303916173764e-10 11.52663959657901 9.87199999999963e-10 1.2099209816167402e-10 12.25608773923 9.839646114485368e-10 1.4295567053471267e-10 14.528537802214396 +r_4413 deoxynucleotide 3'-phosphatase 9.933999999999606e-10 9.251027851177855e-11 9.312490287072904 9.9539999999996e-10 7.334791055781635e-11 7.368687016055786 9.939999999999606e-10 8.697995805138615e-11 8.750498797926518 9.9419999999996e-10 8.347307081155456e-11 8.396003903797816 9.91599999999961e-10 9.965654160794639e-11 10.05007478902282 9.939999999999606e-10 7.723466215766139e-11 7.770086736183547 9.91399999999961e-10 1.0260675235638507e-10 10.349682505183484 9.90199999999962e-10 1.0443247209678831e-10 10.546603928175353 9.91599999999961e-10 9.96565416079462e-11 10.0500747890228 +r_4414 cytosol nonspecific dipeptidase 1.739999999999985e-10 3.822999223726405e-10 219.71259906473784 3.168000000000075e-10 4.661343328304013e-10 147.13836263585557 2.418000000000018e-10 4.3054597195515404e-10 178.0587146216505 3.262000000000081e-10 4.752249233211089e-10 145.6851389702934 2.6598086895961885e-10 4.755229906559694e-10 178.78089973762863 2.4060000000000173e-10 4.335311175059745e-10 180.18749688527487 3.7160000000001136e-10 4.861694274041011e-10 130.83138520023846 3.1499614176468604e-10 4.844282589555752e-10 153.78863253425547 3.040000000000065e-10 4.621977123970709e-10 152.03872118324378 +r_4415 Cytosol non-specific dipeptidase 5.166000000000226e-10 5.598098940028597e-10 108.3642845533944 1.4799999999999923e-10 5.80829986049753e-10 392.4526932768622 -1.0180000000000071e-10 4.1649904476582325e-10 -409.1346215774267 3.5740000000001047e-10 6.655477674563531e-10 186.2192969939377 -3.981150598654656e-11 3.4556703730546316e-10 -868.0079508226594 4.890000000000202e-10 5.649272772364041e-10 115.527050559587 -1.3539999999999968e-10 4.4261272146680087e-10 -326.89270418523034 -4.899999999999989e-11 5.65210485198686e-10 -1153.49078611977 -6.480000000000023e-11 3.6909105332034784e-10 -569.5849588276952 +r_4416 Cytosol non-specific dipeptidase 8.716000000000031e-10 3.687012722050703e-10 42.301660418204335 6.608000000000332e-10 6.143442388179176e-10 92.96976979689566 -6.590000000000025e-11 7.1582796252618e-10 -1086.233630540482 3.204000000000076e-10 6.107523587254871e-10 190.6218348081999 -1.8999999999999983e-11 3.5194285438767126e-10 -1852.3308125666929 7.932000000000304e-10 4.800831760968103e-10 60.52485830771456 -8.080000000000059e-11 4.90631739597817e-10 -607.2174995022442 8.180000000000061e-11 6.449743858415526e-10 788.4772443050705 -8.000000000000005e-13 5.158028407387101e-10 -64475.35509233872 +r_4417 Cytosol non-specific dipeptidase 1.0040000000000076e-10 3.0518595592446975e-10 303.9700756219796 2.600000000000032e-10 4.4456667430833915e-10 170.9871824262822 1.477999999999993e-10 3.588605804253601e-10 242.8014752539661 2.4560000000000213e-10 4.351074622443744e-10 177.1610188291411 1.323999999999998e-10 3.488475009453101e-10 263.47998560824067 2.548000000000028e-10 4.376245686117286e-10 171.75218548340808 2.1559999999999983e-10 4.127356419574556e-10 191.4358265108793 3.032000000000064e-10 4.627230084148827e-10 152.61312942443038 3.4360000000000944e-10 4.778961361461082e-10 139.08502216126166 +r_4418 Cytosol non-specific dipeptidase 5.804000000000272e-10 4.959687863237077e-10 85.45292665811246 3.678000000000112e-10 4.900726417979724e-10 133.24432892821034 3.068000000000067e-10 4.6380683841086146e-10 151.17563181579249 3.8860000000001275e-10 4.919740315194962e-10 126.60165504875974 2.736000000000041e-10 4.5649174904195454e-10 166.8463995036358 3.332000000000087e-10 4.730988527833395e-10 141.98645041516426 5.002000000000212e-10 5.016475755528118e-10 100.28939935081776 4.5680000000001795e-10 5.001837629905106e-10 109.49732114502872 3.2380000000000797e-10 4.683988038924632e-10 144.6568264028572 +r_4419 L-Cysteate transport via proton symport 1.0001761538482852e-10 4.289637595828689e-10 428.8882092743211 9.279599999491794e-11 2.9225684800935285e-10 314.9455235412718 6.520000000000025e-11 2.4690312316868686e-10 378.6857717311133 7.960000000000057e-11 2.7070001052666703e-10 340.0753901088757 7.380000000000045e-11 2.6147128608451693e-10 354.2971356158744 9.617599994521724e-11 2.990259862526905e-10 310.91539097385885 1.2039600000046835e-10 3.2608917493982577e-10 270.84718341021073 7.479999997987767e-11 2.646109669609901e-10 353.7579773157413 6.98000000002109e-11 2.5640028904272855e-10 367.33565765322913 +r_4420 alpha-glucosidase 9.22399999999986e-10 2.9119615217205433e-10 31.56940071249553 8.327999999943607e-10 4.070347595196121e-10 48.87545143160044 8.618000000000065e-10 3.598981318832565e-10 41.76121279685005 7.82000000000034e-10 4.4823674909210144e-10 57.31927737750407 1.5959999999999896e-10 3.738392584497224e-10 234.23512434193285 3.8900000000001256e-10 4.989276357921618e-10 128.25903233731248 9.320000000165307e-10 2.694262758267559e-10 28.908398693345184 7.496000000000398e-10 4.4512859702964716e-10 59.38215008399459 7.702000000000377e-10 4.4478256070271084e-10 57.748969190169966 +r_4421 2-Hydroxyethanesulfonate transport via proton symport 3.599999999999991e-11 1.884438967450162e-10 523.4552687361574 6.473599999802383e-11 1.0871697742007074e-09 1679.3897896593776 3.7348800588212636e-11 1.165781800392544e-09 3121.336648118406 7.480041268075527e-11 2.6537041939661516e-10 354.7713306465353 2.080761267985041e-11 1.4560914855622008e-10 699.7878651269996 1.457000000021042e-11 1.4225421734212764e-10 976.3501533292604 2.6975982300591942e-11 1.6333465299983468e-10 605.4817621831351 1.5883400000000048e-11 2.0038893819207544e-10 1261.6249555641414 1.5971799999999392e-11 1.847973003406962e-10 1157.0223790725106 +r_4422 3-Oxalomalate transport via proton symport 9.421999999999786e-10 3.2385202798067844e-10 34.371898533292914 -4.3680000000001647e-10 5.235079484730079e-10 -119.85072080425554 -7.780000000000054e-11 3.4780936484065175e-10 -447.0557388697293 -1.6699999999999867e-10 3.9082163234607775e-10 -234.0249295485514 -1.2160000000000008e-10 3.8163145639960916e-10 -313.8416582233626 8.738000000000022e-10 4.75309103372481e-10 54.39564012044858 -4.3520000000001624e-10 5.417191633405674e-10 -124.47591069405952 -2.2320000000000043e-10 6.93309379410902e-10 -310.6224818149197 -1.8799999999999806e-10 4.4575300239913015e-10 -237.1026608506036 +r_4423 Gly-Met transport via proton symport 3.37800000000009e-10 5.123901528461726e-10 151.68447390354032 2.538000000000028e-10 4.3752010784528935e-10 172.38774934802387 1.4189999999999943e-10 4.374387506064305e-10 308.2725515196845 1.5512415352347891e-10 8.40144493282288e-10 541.5948929933257 2.0319999999999892e-10 4.0637764278774366e-10 199.98899743491424 1.3439999999999969e-10 5.381399064479426e-10 400.4017161071011 1.3999999999999962e-10 5.437454660283333e-10 388.38961859166784 2.4960000000000243e-10 4.77226769028957e-10 191.1966222071123 1.5299999999999916e-10 4.808713418883432e-10 314.2949946982653 +r_4424 Gly-Gln transport via proton symport 5.804000000000272e-10 4.959687863237077e-10 85.45292665811246 3.678000000000112e-10 4.900726417979724e-10 133.24432892821034 3.068000000000067e-10 4.6380683841086146e-10 151.17563181579249 3.8860000000001275e-10 4.919740315194962e-10 126.60165504875974 2.736000000000041e-10 4.5649174904195454e-10 166.8463995036358 3.332000000000087e-10 4.730988527833395e-10 141.98645041516426 5.002000000000212e-10 5.016475755528118e-10 100.28939935081776 4.5680000000001795e-10 5.001837629905106e-10 109.49732114502872 3.2380000000000797e-10 4.683988038924632e-10 144.6568264028572 +r_4425 Gly-Gln transport via proton symport 5.804000000000272e-10 4.959687863237077e-10 85.45292665811246 3.678000000000112e-10 4.900726417979724e-10 133.24432892821034 3.068000000000067e-10 4.6380683841086146e-10 151.17563181579249 3.8860000000001275e-10 4.919740315194962e-10 126.60165504875974 2.736000000000041e-10 4.5649174904195454e-10 166.8463995036358 3.332000000000087e-10 4.730988527833395e-10 141.98645041516426 5.002000000000212e-10 5.016475755528118e-10 100.28939935081776 4.5680000000001795e-10 5.001837629905106e-10 109.49732114502872 3.2380000000000797e-10 4.683988038924632e-10 144.6568264028572 +r_4426 Ala-Gln transport via proton symport 1.739999999999985e-10 3.822999223726405e-10 219.71259906473784 3.168000000000075e-10 4.661343328304013e-10 147.13836263585557 2.418000000000018e-10 4.3054597195515404e-10 178.0587146216505 3.262000000000081e-10 4.752249233211089e-10 145.6851389702934 2.6598086895961885e-10 4.755229906559694e-10 178.78089973762863 2.4060000000000173e-10 4.335311175059745e-10 180.18749688527487 3.7160000000001136e-10 4.861694274041011e-10 130.83138520023846 3.1499614176468604e-10 4.844282589555752e-10 153.78863253425547 3.040000000000065e-10 4.621977123970709e-10 152.03872118324378 +r_4427 N-Acetylmethionine transport via proton symport 9.96999999999959e-10 6.776369517430939e-11 6.79675979682168 9.989999999999588e-10 3.1610122428867234e-11 3.16417641930616 9.883999999999624e-10 1.4376916886030082e-10 14.545646384086028 9.86799999999963e-10 1.4909797463817632e-10 15.109239424217868 9.86999999999963e-10 1.4434391928102007e-10 14.624510565453445 9.957999999999599e-10 8.113985910356968e-11 8.148208385576716 9.871999999999624e-10 1.4913285393106748e-10 15.106650519760242 9.83599999999964e-10 1.5917319881639408e-10 16.182716431110197 9.823999999999643e-10 1.6029778250435878e-10 16.31695668814786 +r_4428 Phosphotyrosine transport via proton symport 9.91399999999961e-10 9.448717143142971e-11 9.530680999741111 9.939999999999606e-10 7.723466215766028e-11 7.770086736183435 9.871999999999624e-10 1.1242191840361123e-10 11.387957698907565 9.89599999999962e-10 1.0145885264360168e-10 10.252511382741064 9.85999999999963e-10 1.175021759469603e-10 11.917056384073495 9.92199999999961e-10 8.798129427115769e-11 8.867294322834223 9.86799999999963e-10 1.1414186643442392e-10 11.566869318446312 9.871796767822754e-10 1.2978561367292435e-10 13.147111587220092 9.848837359253126e-10 1.2532869978939844e-10 12.725227884045651 +r_4429 Ala-His transport via proton symport 5.166000000000226e-10 5.598098940028597e-10 108.3642845533944 1.4799999999999923e-10 5.80829986049753e-10 392.4526932768622 -1.0180000000000071e-10 4.1649904476582325e-10 -409.1346215774267 3.5740000000001047e-10 6.655477674563531e-10 186.2192969939377 -3.981150598654656e-11 3.4556703730546316e-10 -868.0079508226594 4.890000000000202e-10 5.649272772364041e-10 115.527050559587 -1.3539999999999968e-10 4.4261272146680087e-10 -326.89270418523034 -4.899999999999989e-11 5.65210485198686e-10 -1153.49078611977 -6.480000000000023e-11 3.6909105332034784e-10 -569.5849588276952 +r_4430 Ala-His transport via proton symport 5.166000000000226e-10 5.598098940028597e-10 108.3642845533944 1.4799999999999923e-10 5.80829986049753e-10 392.4526932768622 -1.0180000000000071e-10 4.1649904476582325e-10 -409.1346215774267 3.5740000000001047e-10 6.655477674563531e-10 186.2192969939377 -3.981150598654656e-11 3.4556703730546316e-10 -868.0079508226594 4.890000000000202e-10 5.649272772364041e-10 115.527050559587 -1.3539999999999968e-10 4.4261272146680087e-10 -326.89270418523034 -4.899999999999989e-11 5.65210485198686e-10 -1153.49078611977 -6.480000000000023e-11 3.6909105332034784e-10 -569.5849588276952 +r_4431 ala-L-asp-L transport via proton symport 8.040000000000057e-11 2.7704005168577157e-10 344.5771787136438 9.940000000000079e-11 3.0714574342085755e-10 308.9997418720876 1.3599999999999966e-10 3.4860910151793264e-10 256.3302217043629 1.5159999999999915e-10 3.631030277507208e-10 239.51387054797016 2.5640000000000286e-10 4.493321932423475e-10 175.24656522712266 1.4179999999999947e-10 3.573769769595188e-10 252.02889771475324 1.5979999999999895e-10 3.7508945389025697e-10 234.72431407400464 2.2700000000000072e-10 4.2744302720747887e-10 188.30089304294168 3.3540000000000884e-10 4.759749472714865e-10 141.91262590085694 +r_4432 FMNH2-dependent alkanesulfonate monooxygenase 3.599999999999991e-11 1.884438967450162e-10 523.4552687361574 6.473599999802383e-11 1.0871697742007074e-09 1679.3897896593776 3.7348800588212636e-11 1.165781800392544e-09 3121.336648118406 7.480041268075527e-11 2.6537041939661516e-10 354.7713306465353 2.080761267985041e-11 1.4560914855622008e-10 699.7878651269996 1.457000000021042e-11 1.4225421734212764e-10 976.3501533292604 2.6975982300591942e-11 1.6333465299983468e-10 605.4817621831351 1.5883400000000048e-11 2.0038893819207544e-10 1261.6249555641414 1.5971799999999392e-11 1.847973003406962e-10 1157.0223790725106 +r_4433 thymidine 3-monophosphate transport 9.933999999999606e-10 9.251027851177855e-11 9.312490287072904 9.9539999999996e-10 7.334791055781635e-11 7.368687016055786 9.939999999999606e-10 8.697995805138615e-11 8.750498797926518 9.9419999999996e-10 8.347307081155456e-11 8.396003903797816 9.91599999999961e-10 9.965654160794639e-11 10.05007478902282 9.939999999999606e-10 7.723466215766139e-11 7.770086736183547 9.91399999999961e-10 1.0260675235638507e-10 10.349682505183484 9.90199999999962e-10 1.0443247209678831e-10 10.546603928175353 9.91599999999961e-10 9.96565416079462e-11 10.0500747890228 +r_4434 thymidine 5-monophosphate transport 9.912890608701722e-10 1.3386751156148603e-10 13.50438704972438 9.9419999999996e-10 8.104118418869972e-11 8.15139651867863 9.9419999999996e-10 8.583608545776783e-11 8.633683912469447 9.933999999999606e-10 8.807946184168347e-11 8.86646485219317 9.90199999999962e-10 1.1183229091929691e-10 11.293909404090204 9.945999999999604e-10 7.329334473795692e-11 7.369127763720072 9.911999999999614e-10 1.0161016152426001e-10 10.251226949582724 9.883999999999624e-10 1.1431558778539967e-10 11.565721143808585 9.917999999999614e-10 9.661587305088408e-11 9.741467337254267 +r_4435 glycerol-1-phosphate phosphohydrolase 9.813999999999648e-10 1.4648662623711771e-10 14.926291648372016 9.89399999999962e-10 1.0995479985704526e-10 11.113280761779814 9.889999999999622e-10 1.2199170625611024e-10 12.334854019829615 9.881999999999623e-10 1.1858993513171163e-10 12.00060060025462 9.883999999999624e-10 1.1776337988834848e-10 11.914546730913896 9.883999999999624e-10 1.2111306153645962e-10 12.253446128739805 9.871999999999624e-10 1.2585439152279776e-10 12.748621507577235 9.87342624432624e-10 1.3608438173752269e-10 13.78289343233039 9.84100000000012e-10 1.4353156538581938e-10 14.58505897630501 +r_4436 nucleotide-specific phosphatase (thymidine 5'-monophosphate) 9.912890608701722e-10 1.3386751156148603e-10 13.50438704972438 9.9419999999996e-10 8.104118418869972e-11 8.15139651867863 9.9419999999996e-10 8.583608545776783e-11 8.633683912469447 9.933999999999606e-10 8.807946184168347e-11 8.86646485219317 9.90199999999962e-10 1.1183229091929691e-10 11.293909404090204 9.945999999999604e-10 7.329334473795692e-11 7.369127763720072 9.911999999999614e-10 1.0161016152426001e-10 10.251226949582724 9.883999999999624e-10 1.1431558778539967e-10 11.565721143808585 9.917999999999614e-10 9.661587305088408e-11 9.741467337254267 +r_4437 Gly-Glu transport via proton symport (extracellular to cytosol) 5.26800000000023e-10 5.005315837919418e-10 95.01358841911916 1.9659999999999847e-10 3.999755443614191e-10 203.4463603059116 1.4799999999999928e-10 3.61278430605642e-10 244.1070477065159 4.04000000000014e-10 4.9359165972016e-10 122.17615339607497 1.244e-10 3.3548047548238636e-10 269.6788388122077 5.986000000000284e-10 4.922667013937302e-10 82.23633501398379 4.114000000000146e-10 4.94164830573702e-10 120.11784894839197 2.1719999999999998e-10 4.138337971726448e-10 190.5312141678844 3.4900000000000975e-10 4.783772245349777e-10 137.07083797563442 +r_4438 Gly-Glu transport via proton symport (cytosol to vacuole) 5.26800000000023e-10 5.005315837919418e-10 95.01358841911916 1.9659999999999847e-10 3.999755443614191e-10 203.4463603059116 1.4799999999999928e-10 3.61278430605642e-10 244.1070477065159 4.04000000000014e-10 4.9359165972016e-10 122.17615339607497 1.244e-10 3.3548047548238636e-10 269.6788388122077 5.986000000000284e-10 4.922667013937302e-10 82.23633501398379 4.114000000000146e-10 4.94164830573702e-10 120.11784894839197 2.1719999999999998e-10 4.138337971726448e-10 190.5312141678844 3.4900000000000975e-10 4.783772245349777e-10 137.07083797563442 +r_4439 cytosol nonspecific dipeptidase 5.26800000000023e-10 5.005315837919418e-10 95.01358841911916 1.9659999999999847e-10 3.999755443614191e-10 203.4463603059116 1.4799999999999928e-10 3.61278430605642e-10 244.1070477065159 4.04000000000014e-10 4.9359165972016e-10 122.17615339607497 1.244e-10 3.3548047548238636e-10 269.6788388122077 5.986000000000284e-10 4.922667013937302e-10 82.23633501398379 4.114000000000146e-10 4.94164830573702e-10 120.11784894839197 2.1719999999999998e-10 4.138337971726448e-10 190.5312141678844 3.4900000000000975e-10 4.783772245349777e-10 137.07083797563442 +r_4440 L-methionine transport, vacuoluar -1.3389999999999574e-09 4.97723362631428e-10 -37.17127428166121 -1.2533999999999467e-09 4.669390178698511e-10 -37.253791117749415 -1.1555999999999444e-09 4.1063653572582727e-10 -35.53448734214669 -1.1687241535234215e-09 8.406179820710163e-10 -71.92612384511399 -1.201219131040332e-09 5.005746693342557e-10 -41.67221919790156 -1.2033999999999475e-09 4.22923412502287e-10 -35.14404292025141 -1.209599999999945e-09 4.446429820387187e-10 -36.75950579023966 -1.246199999999949e-09 4.762677043273586e-10 -38.21759784363489 -1.188599999999944e-09 4.4527485212933205e-10 -37.46212789242412 +r_4441 L-threonine transport, vacuoluar -9.293999999999832e-10 2.600560820922327e-10 -27.98107188425193 -9.255999999999843e-10 2.647237347333009e-10 -28.60023063237957 -9.743999999999674e-10 1.592159223884082e-10 -16.33989351276822 -8.614000000000067e-10 3.4556319651340573e-10 -40.11646116942222 -8.933999999999954e-10 3.0992846131040045e-10 -34.69089560223886 -9.393999999999796e-10 2.3945585777249224e-10 -25.49029782547344 -8.796000000000004e-10 3.2607530575160117e-10 -37.07086240923159 -9.169999999999871e-10 2.759098136077342e-10 -30.08831118950251 -9.645999999999708e-10 1.8588639205211326e-10 -19.270826461965463 +r_4442 cysteamine exchange 5.339999999999999e-11 2.3949929432546457e-10 448.5005511712821 7.920000000000055e-11 2.7810578664549755e-10 351.14367000693886 1.0120000000000076e-10 3.0818428822881037e-10 304.5299290798499 1.1480000000000032e-10 3.2379303325685004e-10 282.049680537325 5.880000000000011e-11 2.4526432867048056e-10 417.116205221905 7.920000000000055e-11 2.7738555937486594e-10 350.23429213997974 6.860000000000031e-11 2.5827772160271686e-10 376.4981364471074 5.339999999999999e-11 2.318602851683904e-10 434.1952905775102 6.260000000000019e-11 2.5038725757463835e-10 399.9796446879196 +r_4443 23cGMP transport via diffusion (extracellular to periplasm) 9.825999999999643e-10 1.3675152721648878e-10 13.91731398498817 8.819999999999993e-10 3.2387803166605356e-10 36.72086526826006 9.849999999999634e-10 1.2481232159976992e-10 12.671301685256298 9.827999999999644e-10 1.3002900256597468e-10 13.230464241552644 9.813999999999648e-10 1.3659345355583708e-10 13.918224328086612 9.843999999999634e-10 1.2868547699876155e-10 13.07247836232896 9.876515892413704e-10 1.1384303916173764e-10 11.52663959657901 9.87199999999963e-10 1.2099209816167402e-10 12.25608773923 9.839646114485368e-10 1.4295567053471267e-10 14.528537802214396 +r_4444 D-Glycerate 2-phosphate transport in/out via proton symport 6.03200000000029e-10 4.91322744850992e-10 81.45270969014729 5.046000000000216e-10 5.028214453274356e-10 99.64753177316965 5.762000000000267e-10 4.970341724607237e-10 86.26070330800081 4.97200000000021e-10 5.008416201412514e-10 100.73242561167146 7.224000000000381e-10 4.4919772452578315e-10 62.1813018446511 5.486000000000249e-10 4.99687880176747e-10 91.0841925221882 6.484000000000321e-10 4.80024504275507e-10 74.03215673588576 5.690000000000264e-10 4.968786347545388e-10 87.32489187249838 4.934000000000208e-10 5.031968614928879e-10 101.98558198071883 +r_4445 3-Phospho-D-glycerate transport in/out via proton symport 5.92600000000028e-10 4.938360201554389e-10 83.33378672889225 4.942000000000208e-10 5.028090327198551e-10 101.74201390526794 5.820000000000274e-10 4.957067127132812e-10 85.17297469299963 4.890000000000202e-10 5.007286149494374e-10 102.39848976470684 7.188000000000377e-10 4.5096256324298645e-10 62.73825309445782 4.97200000000021e-10 5.03232360407927e-10 101.21326637327148 6.46000000000032e-10 4.80760050383988e-10 74.42106043095418 5.816000000000271e-10 4.953690726151703e-10 85.17349941801015 4.8460000000002e-10 5.037991690351995e-10 103.96185906627706 +r_4446 D-glucose 1-phosphate transport via diffusion -3.4299723652396366e-05 0.0008084629058357 -2357.053701157948 -1.584297619777329e-05 0.0005607727144695 -3539.5667295669723 -1.5894933165204438e-05 0.0007947051657123 -4999.7389573933215 -6.182829066360438e-05 0.00178422971272 -2885.782048266003 -2.3440023003395988e-05 0.0016575171393946 -7071.311914474171 -5.7320290720137735e-05 0.0020259980331911 -3534.5215590111507 -7.043924562467309e-05 0.0035216487943847 -4999.554954278563 -0.0003203482683764 0.0092431055079697 -2885.330254729928 -0.0001027149479964 0.0051352727318923 -4999.537878429184 +r_4447 carbamoyl phosphate nuclear transport via diffusion -5.907073669848533e-06 0.0002952576509985 -4998.374279732184 -0.0001084175284415 0.0018990927185768 -1751.6473082126265 -2.1016224617464257e-05 0.0008577467559114 -4081.355103136154 -0.000230628848949 0.0030247013518447 -1311.5017334682034 -6.187937603189754e-05 0.0025256686228057 -4081.600017272067 -5.445374878603124e-05 0.0017213088520557 -3161.0474768586096 -9.302187719362097e-05 0.003796812848621 -4081.634302776028 -0.0001412909563303 0.0057669879837589 -4081.639854057493 -0.0001809862930909 0.0063968920655295 -3534.46217184796 +r_4448 Met-Ala transport via proton symport (extracellular to cytosol) 9.865999999999627e-10 1.7443200768512332e-10 17.680114300134793 9.991999999999583e-10 1.600140021878606e-10 16.01421158805717 4.781000000000196e-10 8.89510334806269e-10 186.05110537674813 9.86199999999963e-10 2.383713996788197e-10 24.17069556670337 9.886191310403472e-10 3.2721193521463433e-10 33.09787611234079 9.659999999999708e-10 2.76512733627904e-10 28.624506586740413 6.388000000000312e-10 7.715268049278281e-10 120.77752112207112 8.638000000000054e-10 5.060640079634522e-10 58.58578466814642 5.40000000000024e-10 8.558893090241994e-10 158.49802018965954 +r_4449 Met-Ala transport via proton symport (cytosol to vacuole) 9.865999999999627e-10 1.7443200768512332e-10 17.680114300134793 9.991999999999583e-10 1.600140021878606e-10 16.01421158805717 4.781000000000196e-10 8.89510334806269e-10 186.05110537674813 9.86199999999963e-10 2.383713996788197e-10 24.17069556670337 9.886191310403472e-10 3.2721193521463433e-10 33.09787611234079 9.659999999999708e-10 2.76512733627904e-10 28.624506586740413 6.388000000000312e-10 7.715268049278281e-10 120.77752112207112 8.638000000000054e-10 5.060640079634522e-10 58.58578466814642 5.40000000000024e-10 8.558893090241994e-10 158.49802018965954 +r_4450 O-Phospho-L-serine transport in via proton symport 5.608000000000256e-10 4.987515519997125e-10 88.93572610550812 4.634000000000185e-10 5.015084666767114e-10 108.2236656617806 5.63400000000026e-10 4.996302293428905e-10 88.68126186419371 4.584000000000181e-10 4.99519112616096e-10 108.97013800525228 6.678000000000336e-10 4.731679803066991e-10 70.85474398123314 5.108000000000221e-10 5.015313217869132e-10 98.18545845475562 5.996000000000285e-10 4.932833928900909e-10 82.2687446447744 5.618000000000256e-10 4.974236082547686e-10 88.54104810515237 4.96600000000021e-10 5.04419793292825e-10 101.5746663900128 +r_4451 GMP transport via proton symport 4.6180000000001835e-10 5.013891085849978e-10 108.57278228345125 3.5540000000001037e-10 4.799342740224573e-10 135.04059482904995 5.590000000000257e-10 4.981652674833583e-10 89.1172213744786 3.77000000000012e-10 4.850959323811346e-10 128.67266110905018 5.281919616311348e-10 5.008790547112381e-10 94.82898095693275 4.676311462382797e-10 5.006379746498566e-10 107.0583041093586 5.626000000000261e-10 4.98127359390386e-10 88.54023451659496 5.562000000000252e-10 5.004914168411692e-10 89.98407350613921 6.980000000000361e-10 4.6307546661162786e-10 66.34319005896904 +r_4452 myo-inositol phosphate transport via diffusion (extracellular to periplasm) 1.4498397093551419e-10 9.727513467036931e-10 670.9371666584802 1.5977020128415922e-10 7.514631898792888e-10 470.34001574722566 1.526316038844819e-10 1.03777749134937e-09 679.9230729009466 2.0265189497273435e-10 6.185037784894191e-10 305.2050308104127 1.8016859115991167e-10 7.050791461167494e-10 391.34409698022455 2.5179720407441023e-10 6.61351295525067e-10 262.6523586535245 1.9211392075582735e-10 6.915153539937882e-10 359.95067472111475 2.539464243451695e-10 7.166043609151375e-10 282.1872222705973 1.5154792024671918e-10 5.27293197259737e-10 347.93826032142607 +r_4453 D-glucose 6-phosphate transport -3.4793912210782e-05 0.0008194631274923 -2355.191110812948 -3.059862089609109e-05 0.0007688751308716 -2512.777074112703 -9.486865685189808e-05 0.0019346543744961 -2039.2977393117528 -0.0001102154664434 0.002347999994908 -2130.37250639624 -0.0002571468803895 0.0054770160057107 -2129.9173442872107 -0.000103452820133 0.0026760096917541 -2586.695740447205 -0.0003517638691518 0.0078586734069384 -2234.0763495370843 -0.00053409091472 0.0119319191245232 -2234.061429556093 -0.0006664829033466 0.013055175687408 -1958.816290988549 +r_4454 UMP transport -1.7808831081674335e-05 0.0003360684030464 -1887.088498426584 -3.29806564259865e-05 0.0006224187887636 -1887.2237736092643 -2.908881677850388e-05 0.0006498559524465 -2234.040515964736 -4.4705111019477147e-05 0.0009642194695754 -2156.8439213926345 -0.0001546465118171 0.0025731604936029 -1663.8981787353096 -7.041468890540463e-05 0.0012838320414956 -1823.2446403624167 -9.049938580256584e-05 0.0024171980064178 -2670.9551506694006 -0.0003497759768242 0.0058251443543279 -1665.3929201248022 -0.0002966747629025 0.0052444394117617 -1767.7403229221309 +r_4455 Phosphoenolpyruvate transport in via proton symport 4.964000000000211e-10 5.036246296136772e-10 101.45540483756164 5.352000000000239e-10 5.020073328871426e-10 93.79808163062788 6.284000000000306e-10 4.86169427404096e-10 77.36623606048255 5.112000000000221e-10 5.011235226538321e-10 98.02885810911783 7.6560000000004e-10 4.2555006588145377e-10 55.58386440457571 5.840000000000276e-10 4.949676742977517e-10 84.75473874961101 6.680000000000339e-10 4.726739723496625e-10 70.75957669904767 6.46400000000032e-10 4.802219930745864e-10 74.29176873059444 5.278000000000231e-10 5.040614799755281e-10 95.50236452737887 +r_4456 Mannose 6-phosphate transport via diffusion (extracellular to periplasm) -2.3194130204915628e-05 0.000669255353331 -2885.4513940306406 -3.265490856131297e-05 0.0008158061033132 -2498.2648528368068 -2.3843752877335635e-05 0.0009732128013398 -4081.625935089087 -7.260079545917821e-05 0.0019391735540654 -2671.008687715805 -4.688281250749917e-05 0.0023438471258858 -4999.373972094562 -2.8662803916527123e-05 0.0014330181655545 -4999.574255637427 -0.0002114054902773 0.0060997026897111 -2885.3094977374512 -5.347949754989771e-05 0.0037813888095808 -7070.726133978259 -5.137453425074624e-05 0.0036325592970555 -7070.739131815661 +r_4457 O-Phosphoryl-Ethanolamine transport in via proton symport 1.3799999999999994e-11 2.5144026018299224e-10 1822.0308708912487 1.1400000000000007e-11 1.9919331212447056e-10 1747.3097554778108 7.2e-12 1.294276257298232e-10 1797.605912914211 8.400000000000001e-12 1.0550671226640752e-10 1256.0322888858036 1.96e-11 2.0790499007235183e-10 1060.7397452671016 2.5399999999999988e-11 2.7994734166057846e-10 1102.1548884274746 1.0800000000000023e-10 4.841310530995573e-10 448.2694936107004 1.2400000000000004e-11 1.7507818388964047e-10 1411.9208378196809 7.800000000000003e-12 1.0070346686011764e-10 1291.0700879502258 +r_4458 6-Phospho-D-gluconate transport in/out via proton symport 4.828000000000199e-10 5.025481777244697e-10 104.0903433563482 3.708000000000115e-10 4.838948138161625e-10 130.50021947576792 6.088000000000294e-10 4.89295863551291e-10 80.37054263325683 2.9260000000000564e-10 4.5631884179493244e-10 155.95312433182627 6.326000000000312e-10 4.838016668125005e-10 76.4782906753836 3.942000000000133e-10 4.932088918523364e-10 125.11641092144085 5.344000000000236e-10 5.004665157097766e-10 93.65017135287324 4.98600000000021e-10 5.01246735309007e-10 100.530833395304 4.800000000000195e-10 5.01647615429399e-10 104.50991988112052 +r_4459 MAN1P transport in/out via proton symport 1.1603536821812428e-10 5.10673770902807e-10 440.1018230431588 9.965698439872246e-11 8.692722911273565e-10 872.2642937392557 9.689831308652207e-11 7.839129646120624e-10 809.0057913723368 5.597199396786791e-11 1.18681387629934e-09 2120.3709072445404 1.61690981979324e-10 5.710821215755062e-10 353.1935514180577 1.0743615877466196e-10 6.437800621863264e-10 599.2210346393708 1.1702504188947172e-10 6.195634683699306e-10 529.4281107415443 9.580680154019336e-11 6.886642251052802e-10 718.8051516534225 6.854788952382632e-11 6.427387963352365e-10 937.6492854850468 +r_4460 Pyrophosphate transport in via proton symport -2.336000000000012e-10 4.2879810349710877e-10 -183.5608319765011 -2.732000000000042e-10 4.5453611585453964e-10 -166.37485939038535 -4.594000000000182e-10 5.031920910110935e-10 -109.53245341991152 -1.5099999999999922e-10 3.669140569466237e-10 -242.98944168650704 -2.2480000000000048e-10 4.217825744480221e-10 -187.6257003772336 -2.3877965569926033e-10 4.75459690657117e-10 -199.12068692148216 -4.370000000000165e-10 5.00480864988111e-10 -114.5265137272522 -4.996738511737994e-10 1.05902123329319e-09 -211.94249625138687 -6.374000000000313e-10 4.849415157054857e-10 -76.08119167013837 +r_4461 Choline phosphate intracellular transport 6.751210929551178e-10 1.4713411898641434e-09 217.93737526757425 7.818000000000345e-10 4.1306523041393447e-10 52.835153544885685 -1.3464779912711114e-06 9.525385345713662e-05 -7074.29709766102 6.759999847627497e-10 4.693273220026077e-10 69.42712020434789 -3.972374110887424e-06 0.0002809351109527 -7072.221878165614 -6.1415164344139896e-06 0.000307076565898 -5000.012117159134 5.869601354463537e-10 4.972465309689102e-10 84.7155540794571 5.012398863696432e-10 1.3655582647158604e-09 272.43607339516853 -8.706531302437378e-06 0.0006156882954128 -7071.568159876405 +r_4462 thiosulfate transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4463 AMP transport in/out via proton symport 4.228000000000153e-10 4.952668148014597e-10 117.13973860015174 3.0880000000000683e-10 4.6247739087162125e-10 149.7659944532419 4.228000000000153e-10 4.940536183407357e-10 116.85279525560972 2.612000000000033e-10 4.3933263324334494e-10 168.19779220648527 4.71200000000019e-10 5.000205636899557e-10 106.11641844013916 3.629919527971885e-10 8.388983535281931e-10 231.10659811153 4.6300000000001846e-10 4.990799697075026e-10 107.79265004481267 5.67600000000026e-10 4.96265549780743e-10 87.43226740322763 3.34006637341136e-10 9.29210608773331e-10 278.20124060118195 +r_4464 23cAMP transport via diffusion (extracellular to periplasm) 6.138000000000297e-10 4.885665762819576e-10 79.59703100064097 5.080000000000216e-10 5.524464131550265e-10 108.7492939281502 6.446000000000321e-10 4.795172857838047e-10 74.3898985081882 6.138000000000298e-10 4.8733670025134e-10 79.39666019083033 6.668000000000334e-10 4.739437567232171e-10 71.07734803887121 9.725999999999679e-10 1.8070907878197086e-10 18.57999987476628 6.212000000000303e-10 4.867832696286165e-10 78.36176265753268 7.752000000000367e-10 4.208329598261147e-10 54.28701752142607 8.987999999999934e-10 3.05576889582777e-10 33.99831882318416 +r_4465 Adenosine- 2'-Monophosphate transport in via proton symport 4.908000000000206e-10 5.047438095337522e-10 102.84103698731276 5.698000000000251e-10 5.480766712856073e-10 96.1875519981719 4.3720000000001644e-10 4.997060147929552e-10 114.29689267907968 4.5480000000001775e-10 4.992061711960975e-10 109.76388988480166 4.830000000000197e-10 5.041446542079877e-10 104.37777519833688 6.332000000000313e-10 4.881653624379878e-10 77.09497195798541 4.948000000000209e-10 5.055928053453593e-10 102.18124602775625 5.112000000000221e-10 5.066812658674393e-10 99.11605357343844 5.64600000000026e-10 4.990758011876326e-10 88.39458044413918 +r_4466 CMP transport in/out via proton symport 6.048000000000291e-10 4.913911405902872e-10 81.24853515050654 4.4900000000001727e-10 5.018459622971745e-10 111.76970207063592 4.5837378322213755e-10 4.995466152582904e-10 108.9823706204854 3.46580125476455e-10 4.767909998517914e-10 137.57020810017065 5.332000000000238e-10 5.017450643722457e-10 94.10072475097962 3.474000000000097e-10 4.78705621247919e-10 137.79666702587957 4.186000000000151e-10 4.962089123110696e-10 118.54011283111608 5.324000000000234e-10 5.025940311544029e-10 94.40158361276872 4.3520000000001624e-10 4.95832764171569e-10 113.932160885007 +r_4467 D-glucosamine transport via diffusion (extracellular to periplasm) 9.979999999999591e-10 5.288250478052538e-11 5.298848174401558 9.989999999999588e-10 4.2418862219229535e-11 4.246132354277407 9.943999999999603e-10 8.700663210816392e-11 8.749661314176125 9.943999999999603e-10 9.148942049664468e-11 9.200464651714434 9.937999999999603e-10 8.101155827728824e-11 8.15169634506857 9.9539999999996e-10 8.354780695631979e-11 8.39339029097078 9.957999999999599e-10 6.76999014425557e-11 6.798544029178393 9.903999999999618e-10 1.07285329977618e-10 10.832525240066856 9.883999999999624e-10 1.1605228833040855e-10 11.741429414246555 +r_4468 2-deoxy-D-ribose transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4469 L-Citrulline transport in via proton symport 8.00400000000028e-10 4.0273102494801804e-10 50.31622000849626 3.3400000000000867e-10 4.74646244914639e-10 142.1096541660559 9.231689846299567e-10 2.722436926963477e-10 29.49012555978296 9.35199999999981e-10 2.470084262378965e-10 26.41236379789367 9.300949999562223e-10 2.6022636565924545e-10 27.9784716261773 9.56999999999973e-10 2.0287738130793743e-10 21.199308391634595 9.379999999986975e-10 2.4447485268569056e-10 26.063417130706835 8.40964971875379e-10 3.7132422963197586e-10 44.15454175266192 9.630000000002871e-10 1.9400651459134302e-10 20.14605551311373 +r_4470 Dihydroxyacetone transport via facilitated diffusion 1.0983989593829344e-09 4.314220270625375e-10 39.27735212940337 1.011199999999968e-09 3.9128657149996654e-10 38.69527012460235 1.121999999999951e-09 3.9641825069728557e-10 35.33139489280774 1.0809999999999554e-09 4.000887579061042e-10 37.01098593026092 1.0963999999999601e-09 4.740801518710653e-10 43.23970739429793 1.023399999999958e-09 3.1316458039006887e-10 30.600408480562987 1.2072999999999638e-09 5.617293102229859e-10 46.52773214801646 1.254999999999953e-09 4.899214269665051e-10 39.03756390171503 1.0957999999999552e-09 3.7503398525735245e-10 34.22467469039676 +r_4471 Ala-Leu transport via proton symport (extracellular to cytosol) 8.961999999999944e-10 4.909926422614961e-10 54.78605693611909 7.585513336085324e-10 6.493063247240781e-10 85.59820488815689 -1.1652590939465391e-10 9.918311248929951e-10 -851.1678905107945 6.139241535235105e-10 1.0683603804204539e-09 174.02155857344684 -7.782499142493691e-10 6.09601668283328e-10 -78.32980860284398 8.63682077572417e-10 5.166290442728117e-10 59.817038895251805 -7.409829668837711e-10 6.795619815706103e-10 -91.71087756963313 -5.915877733465839e-10 8.17470264348367e-10 -138.1824136972907 -8.172000000000221e-10 5.711824663642407e-10 -69.89506441069815 +r_4472 Ala-Leu transport via proton symport (cytosol to vacuole) 8.961999999999944e-10 4.909926422614961e-10 54.78605693611909 7.585513336085324e-10 6.493063247240781e-10 85.59820488815689 -1.1652590939465391e-10 9.918311248929951e-10 -851.1678905107945 6.139241535235105e-10 1.0683603804204539e-09 174.02155857344684 -7.782499142493691e-10 6.09601668283328e-10 -78.32980860284398 8.63682077572417e-10 5.166290442728117e-10 59.817038895251805 -7.409829668837711e-10 6.795619815706103e-10 -91.71087756963313 -5.915877733465839e-10 8.17470264348367e-10 -138.1824136972907 -8.172000000000221e-10 5.711824663642407e-10 -69.89506441069815 +r_4473 L-alanylglycine transport via proton antiport 9.81399999999965e-10 2.0164863608387388e-10 20.54703852495222 9.663999999999701e-10 2.0803772720154395e-10 21.527082698835923 9.81199999999965e-10 1.9301298091621247e-10 19.671115054649352 9.940758464764816e-10 7.199515876791262e-10 72.42421091217605 9.643999999999707e-10 2.629571624692034e-10 27.266400090129768 9.851999999999635e-10 1.6669288318178875e-10 16.919699876349465 9.769999999999663e-10 2.0119417441657136e-10 20.593057770376493 9.805999999999654e-10 1.9139217902840215e-10 19.517864473629302 9.663999999999701e-10 2.483613832207605e-10 25.69964644254637 +r_4474 L-alanylglycine transport via proton antiport 9.81399999999965e-10 2.0164863608387388e-10 20.54703852495222 9.663999999999701e-10 2.0803772720154395e-10 21.527082698835923 9.81199999999965e-10 1.9301298091621247e-10 19.671115054649352 9.940758464764816e-10 7.199515876791262e-10 72.42421091217605 9.643999999999707e-10 2.629571624692034e-10 27.266400090129768 9.851999999999635e-10 1.6669288318178875e-10 16.919699876349465 9.769999999999663e-10 2.0119417441657136e-10 20.593057770376493 9.805999999999654e-10 1.9139217902840215e-10 19.517864473629302 9.663999999999701e-10 2.483613832207605e-10 25.69964644254637 +r_4475 N-acetyl-L-glutamate transport -1.666626156372661e-05 0.000480902268614 -2885.483746761261 -2.276493629346412e-05 0.0006568584769452 -2885.39562983012 -5.94523359130001e-05 0.0014009232085198 -2356.3804298116765 -5.750573727611226e-05 0.0016592405571963 -2885.34785534444 -8.207748387081406e-05 0.0028077152917386 -3420.8106283544253 -6.158131330608041e-05 0.0017769630473634 -2885.5556206333054 -0.0002433796230455 0.0059619636370641 -2449.656040410801 -0.0002259579600833 0.0071425866840201 -3161.024591204643 -0.0002165524021892 0.0068453439474746 -3161.056574884367 +r_4476 N-acetyl-L-glutamate transport -1.666626156372661e-05 0.000480902268614 -2885.483746761261 -2.276493629346412e-05 0.0006568584769452 -2885.39562983012 -5.94523359130001e-05 0.0014009232085198 -2356.3804298116765 -5.750573727611226e-05 0.0016592405571963 -2885.34785534444 -8.207748387081406e-05 0.0028077152917386 -3420.8106283544253 -6.158131330608041e-05 0.0017769630473634 -2885.5556206333054 -0.0002433796230455 0.0059619636370641 -2449.6560404108013 -0.0002259579600833 0.0071425866840201 -3161.024591204643 -0.0002165524021892 0.0068453439474746 -3161.056574884367 +r_4477 Lipoamide transport via proton symport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4478 L-methionine S-oxide transport via diffusion (extracellular) -1.232174573116194e-05 0.0003402902063166 -2761.7044998427714 -6.590684161332e-06 0.0002350835812313 -3566.907099122712 -2.562886074710533e-06 0.000181289575972 -7073.649420510111 -1.4637083019135432e-05 0.0005173773649917 -3534.7026748113053 -7.560643698295801e-06 0.0005346829358206 -7071.923465208697 -2.1668467358894745e-05 0.0008844740882712 -4081.8488618587658 -1.1364984639942845e-05 0.0008036905545142 -7071.637841811412 -1.7249658594185322e-05 0.0012198028653453 -7071.46091434231 -1.6570698178591904e-05 0.0011717933400596 -7071.478385705556 +r_4479 Gly-Asn transport via proton symport 1.0040000000000076e-10 3.0518595592446975e-10 303.9700756219796 2.600000000000032e-10 4.4456667430833915e-10 170.9871824262822 1.477999999999993e-10 3.588605804253601e-10 242.8014752539661 2.4560000000000213e-10 4.351074622443744e-10 177.1610188291411 1.323999999999998e-10 3.488475009453101e-10 263.47998560824067 2.548000000000028e-10 4.376245686117286e-10 171.75218548340808 2.1559999999999983e-10 4.127356419574556e-10 191.4358265108793 3.032000000000064e-10 4.627230084148827e-10 152.61312942443038 3.4360000000000944e-10 4.778961361461082e-10 139.08502216126166 +r_4480 Cysteamine transport via proton antiport -5.339999999999999e-11 2.3949929432546457e-10 -448.5005511712821 -7.920000000000055e-11 2.7810578664549755e-10 -351.14367000693886 -1.0120000000000076e-10 3.0818428822881037e-10 -304.5299290798499 -1.1480000000000032e-10 3.2379303325685004e-10 -282.049680537325 -5.880000000000011e-11 2.4526432867048056e-10 -417.116205221905 -7.920000000000055e-11 2.7738555937486594e-10 -350.23429213997974 -6.860000000000031e-11 2.5827772160271686e-10 -376.4981364471074 -5.339999999999999e-11 2.318602851683904e-10 -434.1952905775102 -6.260000000000019e-11 2.5038725757463835e-10 -399.9796446879196 +r_4481 Hydrogen sulfide oxidation 6.515644829974025e-06 0.0002302924870199 3534.4542716710685 1.1860678190810004e-05 0.0004192132992099 3534.480005829547 5.010619645706492e-06 0.0002505059872764 4999.501159324476 1.480385069698687e-05 0.0005232378659667 3534.471379620644 1.4777971390382754e-05 0.000738825066971 4999.502620852437 1.2074320220132694e-05 0.0006036554118292 4999.498115204326 1.110650933981161e-05 0.0007853488462596 7071.068165805754 1.6856923762354194e-05 0.0011919647086369 7071.06898886799 1.619346040633452e-05 0.00114505084895 7071.0695565852975 +r_4482 L-alanine transport in via proton symport -5.4213999999999805e-09 1.3283730481273104e-09 -24.50239879232884 -4.760151333608484e-09 1.8018140209443807e-09 -37.85203231298313 -2.458474090605325e-09 1.7173213628539302e-09 -69.85314058896961 -4.482399999999921e-09 2.046393849081169e-09 -45.65397664378917 -1.7257385797640827e-09 1.352862647303726e-09 -78.39325510638288 -5.2470820775723744e-09 1.6557081052863052e-09 -31.55483525526132 -1.6234170331162451e-09 1.740147930286905e-09 -107.1904442783003 -2.697130785296509e-09 1.986263437358824e-09 -73.64357146442433 -2.1425999999999512e-09 1.688915547665217e-09 -78.82551795319964 +r_4483 Glycine transport (vacuole) -2.526799999999973e-09 1.1884293133571264e-09 -47.032978999411874 -2.0445999999999584e-09 1.0351932983906891e-09 -50.63060248413922 -1.7256999999999584e-09 9.759098267760403e-10 -56.55153426296944 -2.187399999999956e-09 1.081163735520479e-09 -49.42688742436231 -1.6979999999999575e-09 1.036248407551221e-09 -61.02758583929605 -2.3061999999999423e-09 1.1161947581616603e-09 -48.39973801759121 -2.24419999999995e-09 1.1386068878805663e-09 -50.73553550844808 -2.2073999999999554e-09 1.1053640151195212e-09 -50.07538348824606 -2.1357999999999582e-09 1.1682599566300394e-09 -54.69893981786974 +r_4484 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) -2.143994205869836e-05 0.0006430792775964 -2999.445035046565 -3.402144383063742e-05 0.0008557125538695 -2515.215280484189 -3.898766874708295e-05 0.0010362432448105 -2657.874343636013 -9.56769167520238e-05 0.0020539706367205 -2146.7776203993667 -8.76302801087548e-05 0.0026219540541812 -2992.0639885290907 -0.0001121575705785 0.0030591968764112 -2727.5883925005965 -0.0001841887848598 0.0047195102047004 -2562.322243610813 -0.0002064312422141 0.0059100176249153 -2862.947275579221 -0.0001197358193989 0.0044733738343719 -3736.0364315600527 +r_4485 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) 2.865300558239811e-05 0.0004770731725959 1665.002197497325 9.468504386137882e-05 0.0011515862812405 1216.2282809168044 5.854106994823615e-05 0.0008350820026064 1426.4891354819206 7.210410544030242e-05 0.0011131559132584 1543.8176598419568 0.0001721979127269 0.0024857424738681 1443.5380978220185 0.0001353237520086 0.0019991209115593 1477.2875285275309 0.0002739208770689 0.0038180841230125 1393.8638645828214 0.0004082305159418 0.0057519769050932 1409.0021888300976 0.000397195070203 0.005548768351869 1396.9882226968496 +r_4486 Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) 2.865300558239811e-05 0.0004770731725959 1665.002197497325 9.468504386137882e-05 0.0011515862812405 1216.2282809168044 5.854106994823615e-05 0.0008350820026064 1426.4891354819206 7.210410544030242e-05 0.0011131559132584 1543.8176598419568 0.0001721979127269 0.0024857424738681 1443.5380978220185 0.0001353237520086 0.0019991209115593 1477.2875285275309 0.0002739208770689 0.0038180841230125 1393.8638645828214 0.0004082305159418 0.0057519769050932 1409.0021888300976 0.000397195070203 0.005548768351869 1396.9882226968496 +r_4487 4-Maleylacetoacetate cis-trans-isomerase 2.865300558239811e-05 0.0004770731725959 1665.002197497325 9.468504386137882e-05 0.0011515862812405 1216.2282809168044 5.854106994823615e-05 0.0008350820026064 1426.4891354819206 7.210410544030242e-05 0.0011131559132584 1543.8176598419568 0.0001721979127269 0.0024857424738681 1443.5380978220185 0.0001353237520086 0.0019991209115593 1477.2875285275309 0.0002739208770689 0.0038180841230125 1393.8638645828214 0.0004082305159418 0.0057519769050932 1409.0021888300976 0.000397195070203 0.005548768351869 1396.9882226968496 +r_4488 4-fumarylacetoacetate fumarylhydrolase 2.865300558239811e-05 0.0004770731725959 1665.002197497325 9.468504386137882e-05 0.0011515862812405 1216.2282809168044 5.854106994823615e-05 0.0008350820026064 1426.4891354819206 7.210410544030242e-05 0.0011131559132584 1543.8176598419568 0.0001721979127269 0.0024857424738681 1443.5380978220185 0.0001353237520086 0.0019991209115593 1477.2875285275309 0.0002739208768689 0.003818084123027 1393.8638656058158 0.0004082305157418 0.0057519769051073 1409.0021895238488 0.000397195070203 0.005548768351869 1396.9882226968496 +r_4489 L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming) -2.799999999999995e-11 1.7211020999603663e-10 -614.6793214144177 -1.0920000000000047e-10 3.1826972699868957e-10 -291.45579395484265 -3.999999999999999e-12 9.992996147021903e-11 -2498.249036755477 -1.759999999999999e-11 1.3890319945833868e-10 -789.2227241951066 -7.340000000000039e-11 2.7500466452971544e-10 -374.6657554900735 -3.979999999999989e-11 1.9652909386893664e-10 -493.7916931380332 -3.359999999999993e-11 1.9307639860723023e-10 -574.632138711996 -8.260000000000064e-11 2.8105700241715357e-10 -340.26271479074023 -3.85999999999999e-11 1.9979495390204103e-10 -517.6035075182424 +r_4490 Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) -2.799999999999995e-11 1.7211020999603663e-10 -614.6793214144177 -1.0920000000000047e-10 3.1826972699868957e-10 -291.45579395484265 -3.999999999999999e-12 9.992996147021903e-11 -2498.249036755477 -1.759999999999999e-11 1.3890319945833868e-10 -789.2227241951066 -7.340000000000039e-11 2.7500466452971544e-10 -374.6657554900735 -3.979999999999989e-11 1.9652909386893664e-10 -493.7916931380332 -3.359999999999993e-11 1.9307639860723023e-10 -574.632138711996 -8.260000000000064e-11 2.8105700241715357e-10 -340.26271479074023 -3.85999999999999e-11 1.9979495390204103e-10 -517.6035075182424 +r_4491 arabinose reductase (D-arabinose) 8.800000000000005e-12 1.2134869220976904e-10 1378.9624114746475 1.4e-12 6.163440402852683e-11 4402.457430609059 6.000000000000003e-13 4.2426406871193215e-11 7071.067811865535 2.0000000000000004e-12 5.288250478052487e-11 2644.1252390262425 2.000000000000001e-13 8.124826309559379e-11 40624.13154779688 6.000000000000003e-13 1.1046302737153455e-10 18410.504561922426 -1.5399999999999997e-11 1.7311508821229523e-10 -1124.123949430489 4.999999999999991e-11 2.985260852332841e-10 597.0521704665692 -4.000000000000001e-13 5.6572785825160576e-11 -14143.19645629014 +r_4492 D-arabinitol:NAT 4-oxidoreductase 8.800000000000005e-12 1.2134869220976904e-10 1378.9624114746475 1.4e-12 6.163440402852683e-11 4402.457430609059 6.000000000000003e-13 4.2426406871193215e-11 7071.067811865535 2.0000000000000004e-12 5.288250478052487e-11 2644.1252390262425 2.000000000000001e-13 8.124826309559379e-11 40624.13154779688 6.000000000000003e-13 1.1046302737153455e-10 18410.504561922426 -1.5399999999999997e-11 1.7311508821229523e-10 -1124.123949430489 4.999999999999991e-11 2.985260852332841e-10 597.0521704665692 -4.000000000000001e-13 5.6572785825160576e-11 -14143.19645629014 +r_4493 Acetoacetate transport via diffusion -1.3391067593204096e-06 9.472434010544936e-05 -7073.695913051885 -8.016374530076409e-06 0.0002839582285795 -3542.227568263152 -1.0304445133064496e-05 0.0003283491910562 -3186.4810459577247 -3.2256468066437656e-06 0.0002281377026532 -7072.618805733363 -2.474567589349005e-05 0.0008780452652187 -3548.2775616960416 -8.57224795105624e-06 0.0004345205553682 -5068.9219193046565 -4.7072139078969525e-05 0.0014922659400237 -3170.168106276772 -4.238285430611217e-05 0.0017342238731485 -4091.805286692201 -4.748195715921013e-05 0.0017244649920338 -3631.832163639716 +r_4494 methanol exchange -4.5098198716341053e-10 1.76065515185276e-09 -390.4047616018857 6.790334706893117e-10 1.4298783016201307e-09 210.57552585274024 -2.684000000000038e-10 4.783379573484437e-10 -178.21831495843412 -5.66200000000026e-10 6.914572890906326e-10 -122.12244597149432 -2.7780000000000446e-10 4.777790436623576e-10 -171.9866967827034 -5.454000000000244e-10 8.030366203123906e-10 -147.23810420101844 -2.9520000000000576e-10 4.891879198878491e-10 -165.71406500265564 -2.2540000000000056e-10 4.51038276763111e-10 -200.10571284964948 -3.4820000000000977e-10 5.124541753721596e-10 -147.17236512698028 +r_4495 alkaline phosphatase 1.104599999999946e-09 3.244686363567265e-10 29.37431073300221 1.0777999999999466e-09 2.6937273866236207e-10 24.99283157008493 1.0817999999999476e-09 2.890077249711751e-10 26.71544878639204 1.0685999999999502e-09 2.61357421054593e-10 24.45792822895425 1.1497999999999484e-09 3.7548389796571424e-10 32.6564531193017 1.605799999999994e-09 5.000563680968978e-10 31.140638192608023 1.1159999999999455e-09 3.4607506929957517e-10 31.010310869139072 1.2863999999999547e-09 4.741518786220274e-10 36.85882141029572 1.463399999999974e-09 5.148916999647112e-10 35.18461801043601 +r_4496 Ala-Gly exchange -9.81399999999965e-10 2.0164863608387388e-10 -20.54703852495222 -9.663999999999701e-10 2.0803772720154395e-10 -21.527082698835923 -9.81199999999965e-10 1.9301298091621247e-10 -19.671115054649352 -9.940758464764816e-10 7.199515876791262e-10 -72.42421091217605 -9.643999999999707e-10 2.629571624692034e-10 -27.266400090129768 -9.851999999999635e-10 1.6669288318178875e-10 -16.919699876349465 -9.769999999999663e-10 2.0119417441657136e-10 -20.593057770376493 -9.805999999999654e-10 1.9139217902840215e-10 -19.517864473629302 -9.663999999999701e-10 2.483613832207605e-10 -25.69964644254637 +r_4497 3-oxalomalate(3-) exchange -9.421999999999786e-10 3.2385202798067844e-10 -34.371898533292914 4.3680000000001647e-10 5.235079484730079e-10 119.85072080425554 7.780000000000054e-11 3.4780936484065175e-10 447.0557388697293 1.6699999999999867e-10 3.9082163234607775e-10 234.0249295485514 1.2160000000000008e-10 3.8163145639960916e-10 313.8416582233626 -8.738000000000022e-10 4.75309103372481e-10 -54.39564012044858 4.3520000000001624e-10 5.417191633405674e-10 124.47591069405952 2.2320000000000043e-10 6.93309379410902e-10 310.6224818149197 1.8799999999999806e-10 4.4575300239913015e-10 237.1026608506036 +r_4498 6-O-alpha-D-glucopyranosyl-D-fructofuranose exchange -2.9000000000000536e-10 4.542480250410136e-10 -156.63725001413968 -8.330000000000166e-10 3.7301317371581804e-10 -44.77949264295447 -1.3509999999999972e-10 3.449953541120121e-10 -255.3629564115565 -2.430000000000019e-10 4.29404095899784e-10 -176.70950448550644 -8.620000000000072e-11 2.828171796610214e-10 -328.0941759408573 -2.4640000000000217e-10 4.309572888778726e-10 -174.90149710952468 -1.0660000000000058e-10 3.112166627323153e-10 -291.948088867086 -1.2220000000000008e-10 3.2754941264418486e-10 -268.04370920146044 -1.4839999999999928e-10 3.5553160273609365e-10 -239.5765517089591 +r_4499 5-dehydro-D-gluconate exchange -8.028000000000272e-10 4.1658956944923105e-10 -51.892073922423634 -8.02600000000027e-10 4.0157875080561926e-10 -50.03473097503185 -1.9199999999999983e-11 1.401259685333539e-10 -729.8227527778855 -7.040000000000037e-11 2.665671615377919e-10 -378.6465362752706 -1.699999999999999e-11 1.411204556278101e-10 -830.1203272224129 -7.590000000000405e-10 4.5360792765383917e-10 -59.76389033647099 -1.8599999999999983e-11 1.3805017772648768e-10 -742.2052565940205 -2.1399999999999973e-11 2.1012108455372054e-10 -981.874226886546 -1.4400000000000002e-11 1.1914478207550577e-10 -827.3943199687899 +r_4500 D-tagatose exchange -9.973999999999594e-10 5.4715982745025655e-11 -5.485861514440335 -9.973999999999594e-10 6.778022448890859e-11 -6.795691246131078 -9.9539999999996e-10 8.354780695632103e-11 -8.393390290970904 -9.959999999999598e-10 7.473364050683722e-11 -7.503377560927735 -9.951999999999601e-10 7.468651561776135e-11 -7.504673996961851 -9.951999999999601e-10 7.986385695124196e-11 -8.02490524027785 -9.947999999999602e-10 7.729265703135543e-11 -7.769667976614246 -9.917999999999614e-10 1.0067167902340242e-10 -10.150401192115984 -9.903999999999618e-10 1.1794330046435025e-10 -11.908653116352465 +r_4501 turanose exchange -9.22399999999986e-10 2.9119615217205433e-10 -31.56940071249553 -8.327999999943607e-10 4.070347595196121e-10 -48.87545143160044 -8.618000000000065e-10 3.598981318832565e-10 -41.76121279685005 -7.82000000000034e-10 4.4823674909210144e-10 -57.31927737750407 -1.5959999999999896e-10 3.738392584497224e-10 -234.23512434193285 -3.8900000000001256e-10 4.989276357921618e-10 -128.25903233731248 -9.320000000165307e-10 2.694262758267559e-10 -28.908398693345184 -7.496000000000398e-10 4.4512859702964716e-10 -59.38215008399459 -7.702000000000377e-10 4.4478256070271084e-10 -57.748969190169966 +r_4502 D-glucose 6-phosphate exchange 3.4793912210782006e-05 0.0008194631274923 2355.1911108129475 3.059862089609109e-05 0.0007688751308716 2512.777074112704 9.486865685189808e-05 0.0019346543744961 2039.2977393117528 0.0001102154664434 0.002347999994908 2130.37250639624 0.0002571468803895 0.0054770160057107 2129.9173442872107 0.000103452820133 0.0026760096917541 2586.695740447205 0.0003517638691518 0.0078586734069384 2234.0763495370843 0.00053409091472 0.0119319191245232 2234.061429556093 0.0006664829033466 0.013055175687408 1958.816290988549 +r_4503 alpha-maltotriose exchange -9.657999999999703e-10 1.8394870868121526e-10 -19.046252710832565 -9.52599999988662e-10 2.1900418389940342e-10 -22.99015157484884 -9.647999999999707e-10 1.8538563473666006e-10 -19.214928973535 -9.681999999999707e-10 1.9389759992287408e-10 -20.026606065160088 -2.1459999999999976e-10 4.14464951762196e-10 -193.13371470745403 -9.84999999999964e-10 1.5224859909760679e-10 -15.456710568285514 -9.385999999999796e-10 2.442170518077608e-10 -26.01928955974495 -9.80399999999965e-10 1.4703796799739824e-10 -14.997752753713122 -9.729999999999676e-10 1.6576035502814612e-10 -17.036007711012502 +r_4504 D-glucose 1-phosphate exchange 3.4299723652396366e-05 0.0008084629058357 2357.053701157948 1.584297619777329e-05 0.0005607727144695 3539.5667295669723 1.5894933165204438e-05 0.0007947051657123 4999.7389573933215 6.182829066360436e-05 0.00178422971272 2885.7820482660045 2.3440023003395984e-05 0.0016575171393946 7071.311914474171 5.7320290720137735e-05 0.0020259980331911 3534.5215590111507 7.043924562467309e-05 0.0035216487943847 4999.554954278563 0.0003203482683764 0.0092431055079697 2885.330254729927 0.0001027149479964 0.0051352727318923 4999.537878429183 +r_4505 methyl alpha-D-glucopyranoside exchange 4.5098198716341053e-10 1.76065515185276e-09 390.4047616018857 -6.790334706893117e-10 1.4298783016201307e-09 -210.57552585274024 2.684000000000038e-10 4.783379573484437e-10 178.21831495843412 5.66200000000026e-10 6.914572890906326e-10 122.12244597149432 2.7780000000000446e-10 4.777790436623576e-10 171.9866967827034 5.454000000000244e-10 8.030366203123906e-10 147.23810420101844 2.9520000000000576e-10 4.891879198878491e-10 165.71406500265564 2.2540000000000056e-10 4.51038276763111e-10 200.10571284964948 3.4820000000000977e-10 5.124541753721596e-10 147.17236512698028 +r_4506 D-Glucosamine exchange -9.979999999999591e-10 5.288250478052538e-11 -5.298848174401558 -9.989999999999588e-10 4.2418862219229535e-11 -4.246132354277407 -9.943999999999603e-10 8.700663210816392e-11 -8.749661314176125 -9.943999999999603e-10 9.148942049664468e-11 -9.200464651714434 -9.937999999999603e-10 8.101155827728824e-11 -8.15169634506857 -9.9539999999996e-10 8.354780695631979e-11 -8.39339029097078 -9.957999999999599e-10 6.76999014425557e-11 -6.798544029178393 -9.903999999999618e-10 1.07285329977618e-10 -10.832525240066856 -9.883999999999624e-10 1.1605228833040855e-10 -11.741429414246555 +r_4507 glycerone exchange -1.0983989593829344e-09 4.314220270625375e-10 -39.27735212940337 -1.011199999999968e-09 3.9128657149996654e-10 -38.69527012460235 -1.121999999999951e-09 3.9641825069728557e-10 -35.33139489280774 -1.0809999999999554e-09 4.000887579061042e-10 -37.01098593026092 -1.0963999999999601e-09 4.740801518710653e-10 -43.23970739429793 -1.023399999999958e-09 3.1316458039006887e-10 -30.600408480562987 -1.2072999999999638e-09 5.617293102229859e-10 -46.52773214801646 -1.254999999999953e-09 4.899214269665051e-10 -39.03756390171503 -1.0957999999999552e-09 3.7503398525735245e-10 -34.22467469039676 +r_4508 Ala-Gln exchange -1.739999999999985e-10 3.822999223726405e-10 -219.71259906473784 -3.168000000000075e-10 4.661343328304013e-10 -147.13836263585557 -2.418000000000018e-10 4.3054597195515404e-10 -178.0587146216505 -3.262000000000081e-10 4.752249233211089e-10 -145.6851389702934 -2.6598086895961885e-10 4.755229906559694e-10 -178.78089973762863 -2.4060000000000173e-10 4.335311175059745e-10 -180.18749688527487 -3.7160000000001136e-10 4.861694274041011e-10 -130.83138520023846 -3.1499614176468604e-10 4.844282589555752e-10 -153.78863253425547 -3.040000000000065e-10 4.621977123970709e-10 -152.03872118324378 +r_4509 Ala-Leu exchange -8.961999999999944e-10 4.909926422614961e-10 -54.78605693611909 -7.585513336085324e-10 6.493063247240781e-10 -85.59820488815689 1.1652590939465391e-10 9.918311248929951e-10 851.1678905107945 -6.139241535235105e-10 1.0683603804204539e-09 -174.02155857344684 7.782499142493691e-10 6.09601668283328e-10 78.32980860284398 -8.63682077572417e-10 5.166290442728117e-10 -59.817038895251805 7.409829668837711e-10 6.795619815706103e-10 91.71087756963313 5.915877733465839e-10 8.17470264348367e-10 138.1824136972907 8.172000000000221e-10 5.711824663642407e-10 69.89506441069815 +r_4510 Gly-Gln exchange -5.804000000000272e-10 4.959687863237077e-10 -85.45292665811246 -3.678000000000112e-10 4.900726417979724e-10 -133.24432892821034 -3.068000000000067e-10 4.6380683841086146e-10 -151.17563181579249 -3.8860000000001275e-10 4.919740315194962e-10 -126.60165504875974 -2.736000000000041e-10 4.5649174904195454e-10 -166.8463995036358 -3.332000000000087e-10 4.730988527833395e-10 -141.98645041516426 -5.002000000000212e-10 5.016475755528118e-10 -100.28939935081776 -4.5680000000001795e-10 5.001837629905106e-10 -109.49732114502872 -3.2380000000000797e-10 4.683988038924632e-10 -144.6568264028572 +r_4511 Ala-His exchange -5.166000000000226e-10 5.598098940028597e-10 -108.3642845533944 -1.4799999999999923e-10 5.80829986049753e-10 -392.4526932768622 1.0180000000000071e-10 4.1649904476582325e-10 409.1346215774267 -3.5740000000001047e-10 6.655477674563531e-10 -186.2192969939377 3.981150598654656e-11 3.4556703730546316e-10 868.0079508226594 -4.890000000000202e-10 5.649272772364041e-10 -115.527050559587 1.3539999999999968e-10 4.4261272146680087e-10 326.89270418523034 4.899999999999989e-11 5.65210485198686e-10 1153.49078611977 6.480000000000023e-11 3.6909105332034784e-10 569.5849588276952 +r_4512 Gly-Asn exchange -1.0040000000000076e-10 3.0518595592446975e-10 -303.9700756219796 -2.600000000000032e-10 4.4456667430833915e-10 -170.9871824262822 -1.477999999999993e-10 3.588605804253601e-10 -242.8014752539661 -2.4560000000000213e-10 4.351074622443744e-10 -177.1610188291411 -1.323999999999998e-10 3.488475009453101e-10 -263.47998560824067 -2.548000000000028e-10 4.376245686117286e-10 -171.75218548340808 -2.1559999999999983e-10 4.127356419574556e-10 -191.4358265108793 -3.032000000000064e-10 4.627230084148827e-10 -152.61312942443038 -3.4360000000000944e-10 4.778961361461082e-10 -139.08502216126166 +r_4513 Ala-Glu exchange -9.145999999999879e-10 2.865715698615779e-10 -31.33299473666976 -8.110000000000241e-10 3.956138294605176e-10 -48.78099006911292 -9.055999999999912e-10 2.951373599059429e-10 -32.59025617335974 -7.326000000000385e-10 4.4624776460336726e-10 -60.91288078123721 -8.740000000000074e-11 2.8944428755655145e-10 -331.1719537260286 -7.676000000000392e-10 4.2335101891578727e-10 -55.15255587750983 -4.3340000000001615e-10 4.980100830390555e-10 -114.90772566659832 -8.69522416879099e-10 3.4410567095223234e-10 -39.57410002002027 -8.796000000000004e-10 3.363427794572889e-10 -38.23815137076953 +r_4514 Gly-Met exchange -3.37800000000009e-10 5.123901528461726e-10 -151.68447390354032 -2.538000000000028e-10 4.3752010784528935e-10 -172.38774934802387 -1.4189999999999943e-10 4.374387506064305e-10 -308.2725515196845 -1.5512415352347891e-10 8.40144493282288e-10 -541.5948929933257 -2.0319999999999892e-10 4.0637764278774366e-10 -199.98899743491424 -1.3439999999999969e-10 5.381399064479426e-10 -400.4017161071011 -1.3999999999999962e-10 5.437454660283333e-10 -388.38961859166784 -2.4960000000000243e-10 4.77226769028957e-10 -191.1966222071123 -1.5299999999999916e-10 4.808713418883432e-10 -314.2949946982653 +r_4515 Ala-Asp exchange -8.040000000000057e-11 2.7704005168577157e-10 -344.5771787136438 -9.940000000000079e-11 3.0714574342085755e-10 -308.9997418720876 -1.3599999999999966e-10 3.4860910151793264e-10 -256.3302217043629 -1.5159999999999915e-10 3.631030277507208e-10 -239.51387054797016 -2.5640000000000286e-10 4.493321932423475e-10 -175.24656522712266 -1.4179999999999947e-10 3.573769769595188e-10 -252.02889771475324 -1.5979999999999895e-10 3.7508945389025697e-10 -234.72431407400464 -2.2700000000000072e-10 4.2744302720747887e-10 -188.30089304294168 -3.3540000000000884e-10 4.759749472714865e-10 -141.91262590085694 +r_4516 Gly-Glu exchange -5.26800000000023e-10 5.005315837919418e-10 -95.01358841911916 -1.9659999999999847e-10 3.999755443614191e-10 -203.4463603059116 -1.4799999999999928e-10 3.61278430605642e-10 -244.1070477065159 -4.04000000000014e-10 4.9359165972016e-10 -122.17615339607497 -1.244e-10 3.3548047548238636e-10 -269.6788388122077 -5.986000000000284e-10 4.922667013937302e-10 -82.23633501398379 -4.114000000000146e-10 4.94164830573702e-10 -120.11784894839197 -2.1719999999999998e-10 4.138337971726448e-10 -190.5312141678844 -3.4900000000000975e-10 4.783772245349777e-10 -137.07083797563442 +r_4517 Ala-Thr exchange -8.716000000000031e-10 3.687012722050703e-10 -42.301660418204335 -6.608000000000332e-10 6.143442388179176e-10 -92.96976979689566 6.590000000000025e-11 7.1582796252618e-10 1086.233630540482 -3.204000000000076e-10 6.107523587254871e-10 -190.6218348081999 1.8999999999999983e-11 3.5194285438767126e-10 1852.3308125666929 -7.932000000000304e-10 4.800831760968103e-10 -60.52485830771456 8.080000000000059e-11 4.90631739597817e-10 607.2174995022442 -8.180000000000061e-11 6.449743858415526e-10 -788.4772443050705 8.000000000000005e-13 5.158028407387101e-10 64475.35509233872 +r_4518 Met-Ala exchange -9.865999999999627e-10 1.7443200768512332e-10 -17.680114300134793 -9.991999999999583e-10 1.600140021878606e-10 -16.01421158805717 -4.781000000000196e-10 8.89510334806269e-10 -186.05110537674813 -9.86199999999963e-10 2.383713996788197e-10 -24.17069556670337 -9.886191310403472e-10 3.2721193521463433e-10 -33.09787611234079 -9.659999999999708e-10 2.76512733627904e-10 -28.624506586740413 -6.388000000000312e-10 7.715268049278281e-10 -120.77752112207112 -8.638000000000054e-10 5.060640079634522e-10 -58.58578466814642 -5.40000000000024e-10 8.558893090241994e-10 -158.49802018965954 +r_4519 L-citrulline exchange -8.00400000000028e-10 4.0273102494801804e-10 -50.31622000849626 -3.3400000000000867e-10 4.74646244914639e-10 -142.1096541660559 -9.231689846299567e-10 2.722436926963477e-10 -29.49012555978296 -9.35199999999981e-10 2.470084262378965e-10 -26.41236379789367 -9.300949999562223e-10 2.6022636565924545e-10 -27.9784716261773 -9.56999999999973e-10 2.0287738130793743e-10 -21.199308391634595 -9.379999999986975e-10 2.4447485268569056e-10 -26.063417130706835 -8.40964971875379e-10 3.7132422963197586e-10 -44.15454175266192 -9.630000000002871e-10 1.9400651459134302e-10 -20.14605551311373 +r_4520 2-aminobutanoate exchange -9.979999999999591e-10 5.997265496765066e-11 -6.009284064895104 -9.899999999999614e-10 1.3821657195921188e-10 -13.961269894870428 -9.871999999999624e-10 1.5697480121868058e-10 -15.901013089413135 -9.86999999999963e-10 1.5885857612807875e-10 -16.095093832632696 -9.91599999999961e-10 1.262245084177638e-10 -12.729377613732224 -9.929999999999611e-10 1.1555808381132851e-10 -11.637269265995275 -9.887999999999623e-10 1.4240300461418046e-10 -14.401598363085144 -9.89399999999962e-10 1.4032668426091228e-10 -14.183008314222526 -9.92199999999961e-10 1.1892009248936107e-10 -11.985496118662136 +r_4521 choline phosphate exchange -6.751210929551178e-10 1.4713411898641434e-09 -217.93737526757425 -7.818000000000345e-10 4.1306523041393447e-10 -52.835153544885685 1.3464779912711116e-06 9.525385345713665e-05 7074.29709766102 -6.759999847627497e-10 4.693273220026077e-10 -69.42712020434789 3.972374110887424e-06 0.0002809351109527 7072.221878165614 6.14151643441399e-06 0.000307076565898 5000.012117159133 -5.869601354463537e-10 4.972465309689102e-10 -84.7155540794571 -5.012398863696432e-10 1.3655582647158604e-09 -272.43607339516853 8.706531302437378e-06 0.0006156882954128 7071.568159876405 +r_4522 glycerol 1-phosphate exchange -9.813999999999648e-10 1.4648662623711771e-10 -14.926291648372016 -9.89399999999962e-10 1.0995479985704526e-10 -11.113280761779814 -9.889999999999622e-10 1.2199170625611024e-10 -12.334854019829615 -9.881999999999623e-10 1.1858993513171163e-10 -12.00060060025462 -9.883999999999624e-10 1.1776337988834848e-10 -11.914546730913896 -9.883999999999624e-10 1.2111306153645962e-10 -12.253446128739805 -9.871999999999624e-10 1.2585439152279776e-10 -12.748621507577235 -9.87342624432624e-10 1.3608438173752269e-10 -13.78289343233039 -9.84100000000012e-10 1.4353156538581938e-10 -14.58505897630501 +r_4523 2-phospho-D-glyceric acid exchange -6.03200000000029e-10 4.91322744850992e-10 -81.45270969014729 -5.046000000000216e-10 5.028214453274356e-10 -99.64753177316965 -5.762000000000267e-10 4.970341724607237e-10 -86.26070330800081 -4.97200000000021e-10 5.008416201412514e-10 -100.73242561167146 -7.224000000000381e-10 4.4919772452578315e-10 -62.1813018446511 -5.486000000000249e-10 4.99687880176747e-10 -91.0841925221882 -6.484000000000321e-10 4.80024504275507e-10 -74.03215673588576 -5.690000000000264e-10 4.968786347545388e-10 -87.32489187249838 -4.934000000000208e-10 5.031968614928879e-10 -101.98558198071883 +r_4524 GMP exchange -4.6180000000001835e-10 5.013891085849978e-10 -108.57278228345125 -3.5540000000001037e-10 4.799342740224573e-10 -135.04059482904995 -5.590000000000257e-10 4.981652674833583e-10 -89.1172213744786 -3.77000000000012e-10 4.850959323811346e-10 -128.67266110905018 -5.281919616311348e-10 5.008790547112381e-10 -94.82898095693275 -4.676311462382797e-10 5.006379746498566e-10 -107.0583041093586 -5.626000000000261e-10 4.98127359390386e-10 -88.54023451659496 -5.562000000000252e-10 5.004914168411692e-10 -89.98407350613921 -6.980000000000361e-10 4.6307546661162786e-10 -66.34319005896904 +r_4525 3-phospho-serine exchange -5.608000000000256e-10 4.987515519997125e-10 -88.93572610550812 -4.634000000000185e-10 5.015084666767114e-10 -108.2236656617806 -5.63400000000026e-10 4.996302293428905e-10 -88.68126186419371 -4.584000000000181e-10 4.99519112616096e-10 -108.97013800525228 -6.678000000000336e-10 4.731679803066991e-10 -70.85474398123314 -5.108000000000221e-10 5.015313217869132e-10 -98.18545845475562 -5.996000000000285e-10 4.932833928900909e-10 -82.2687446447744 -5.618000000000256e-10 4.974236082547686e-10 -88.54104810515237 -4.96600000000021e-10 5.04419793292825e-10 -101.5746663900128 +r_4526 O-phosphonatooxy-D-serine(2-) exchange -9.593693553831396e-10 3.812573054171452e-10 -39.74040897573635 -7.99600000000028e-10 5.179705577537583e-10 -64.77870907375438 3.494000000000099e-10 5.386814230462048e-10 154.17327505615043 -4.1974745808207197e-10 1.3065886944151366e-09 -311.27971575700724 7.840000000000054e-11 3.6644275959447405e-10 467.40147907458106 -9.121999999999892e-10 3.6071759513045404e-10 -39.54369602394853 2.5920000000000315e-10 5.127064789786583e-10 197.80342553188737 1.8959999999999803e-10 6.84796049291911e-10 361.1793508923619 4.0580000000001415e-10 5.407262125765568e-10 133.2494363175303 +r_4527 diphosphate exchange 2.336000000000012e-10 4.2879810349710877e-10 183.5608319765011 2.732000000000042e-10 4.5453611585453964e-10 166.37485939038535 4.594000000000182e-10 5.031920910110935e-10 109.53245341991152 1.5099999999999922e-10 3.669140569466237e-10 242.98944168650704 2.2480000000000048e-10 4.217825744480221e-10 187.6257003772336 2.3877965569926033e-10 4.75459690657117e-10 199.12068692148216 4.370000000000165e-10 5.00480864988111e-10 114.5265137272522 4.996738511737994e-10 1.05902123329319e-09 211.94249625138687 6.374000000000313e-10 4.849415157054857e-10 76.08119167013837 +r_4528 triphosphate exchange -9.89199999999962e-10 1.0337067814142655e-10 -10.44992702602411 -9.911999999999614e-10 9.340398739332839e-11 -9.423323990449155 -9.933999999999606e-10 8.097994535877968e-11 -8.151796392065924 -9.917410333546136e-10 2.0221396013238664e-10 -20.38979464713564 -9.917999999999614e-10 9.019083588355848e-11 -9.09365153090966 -9.861957919916156e-10 4.744810716839918e-10 -48.11225879658039 -9.874622938992356e-10 4.00257156555868e-10 -40.53391800666687 -9.907999999999615e-10 9.548394334487688e-11 -9.637055242721091 -9.927999999999604e-10 8.455524772587452e-11 -8.51684606425039 +r_4529 phosphoenolpyruvate exchange -4.964000000000211e-10 5.036246296136772e-10 -101.45540483756164 -5.352000000000239e-10 5.020073328871426e-10 -93.79808163062788 -6.284000000000306e-10 4.86169427404096e-10 -77.36623606048255 -5.112000000000221e-10 5.011235226538321e-10 -98.02885810911783 -7.6560000000004e-10 4.2555006588145377e-10 -55.58386440457571 -5.840000000000276e-10 4.949676742977517e-10 -84.75473874961101 -6.680000000000339e-10 4.726739723496625e-10 -70.75957669904767 -6.46400000000032e-10 4.802219930745864e-10 -74.29176873059444 -5.278000000000231e-10 5.040614799755281e-10 -95.50236452737887 +r_4530 N(omega)-phospho-L-arginine exchange -9.987999999999587e-10 3.998599474760312e-11 -4.003403559031314 -9.979999999999591e-10 5.6538830266158864e-11 -5.665213453523164 -9.987999999999587e-10 3.998599474760104e-11 -4.003403559031106 -9.98199999999959e-10 5.096351102398083e-11 -5.1055410763356965 -9.991999999999587e-10 3.463524101235226e-11 -3.466297138946526 -9.985999999999587e-10 4.6887948301661096e-11 -4.695368345850494 -9.97199999999959e-10 5.994062541979014e-11 -6.010893042498253 -9.967999999999596e-10 5.99205982581892e-11 -6.011295972932547 -9.973999999999594e-10 5.82573496115051e-11 -5.84092135667811 +r_4531 carbamoyl phosphate exchange 5.907073669848533e-06 0.0002952576509985 4998.374279732183 0.0001084175284415 0.0018990927185768 1751.6473082126265 2.1016224617464257e-05 0.0008577467559114 4081.355103136154 0.000230628848949 0.0030247013518447 1311.5017334682034 6.187937603189754e-05 0.0025256686228057 4081.600017272067 5.445374878603124e-05 0.0017213088520557 3161.0474768586096 9.302187719362097e-05 0.003796812848621 4081.634302776028 0.0001412909563303 0.0057669879837589 4081.639854057493 0.0001809862930909 0.0063968920655295 3534.46217184796 +r_4532 O-phosphoethanolamine exchange -1.3799999999999994e-11 2.5144026018299224e-10 -1822.0308708912487 -1.1400000000000007e-11 1.9919331212447056e-10 -1747.3097554778108 -7.2e-12 1.294276257298232e-10 -1797.605912914211 -8.400000000000001e-12 1.0550671226640752e-10 -1256.0322888858036 -1.96e-11 2.0790499007235183e-10 -1060.7397452671016 -2.5399999999999988e-11 2.7994734166057846e-10 -1102.1548884274746 -1.0800000000000023e-10 4.841310530995573e-10 -448.2694936107004 -1.2400000000000004e-11 1.7507818388964047e-10 -1411.9208378196809 -7.800000000000003e-12 1.0070346686011764e-10 -1291.0700879502258 +r_4533 cysteamine S-phosphate exchange -1.0779212996233322e-10 4.6178357080416086e-10 -428.40193524845097 -1.0577999999999551e-09 3.0931908389093596e-10 -29.24173604565599 -2.686000000000034e-10 4.838397050387886e-10 -180.13391848055934 -1.0685707670773404e-09 9.489552198939352e-10 -88.80602475111995 -2.2628366301326456e-10 5.387045465067652e-10 -238.06603593613693 -1.3407491297424526e-10 9.32183004226125e-10 -695.2702661124902 -2.59200000000003e-10 4.703824103029017e-10 -181.4746953329076 -1.6966799949982604e-10 1.6134897572686134e-09 -950.9688108689394 -2.3180000000000108e-10 4.5266957258952504e-10 -195.28454382636883 +r_4534 guanosine 2'-monophosphate exchange -3.81999999999999e-11 1.9786002556843612e-10 -517.9581821163264 -1.2879999999999988e-10 3.373919481335238e-10 -261.9502702900032 -3.279999999999992e-11 1.8582536482741763e-10 -566.5407464250551 -3.4399999999999915e-11 1.8661083762992427e-10 -542.4733652032696 -4.199999999999988e-11 2.0553454427365942e-10 -489.3679625563334 -3.639999999999991e-11 1.915264380582928e-10 -526.1715331271794 -3.959999999999989e-11 2.040592267789039e-10 -515.3010777245062 -3.899409072897641e-11 2.134193940658336e-10 -547.3121441635315 -5.1999999999999956e-11 2.2384374283022304e-10 -430.4687362119678 +r_4535 glycerol 2-phosphate(2-) exchange -9.847999999999638e-10 1.3628160013334848e-10 -13.838505293801123 -9.89599999999962e-10 1.1087965935992088e-10 -11.204492659652905 -9.877999999999626e-10 1.2511710857501438e-10 -12.666238972972174 -9.89399999999962e-10 1.1175928609116152e-10 -11.295662633026662 -9.89399999999962e-10 1.1528355502677684e-10 -11.651865274588769 -9.89399999999962e-10 1.17005889063819e-10 -11.825943911847936 -9.88599999999962e-10 1.1862906292689429e-10 -11.999702905816184 -9.878978260069983e-10 1.2046985345670912e-10 -12.194566106460458 -9.833333333332975e-10 1.4949553246599264e-10 -15.202935505016754 +r_4536 3'-GMP exchange -9.96999999999959e-10 5.4695505479554e-11 -5.486008573676653 -9.98199999999959e-10 4.239244536335445e-11 -4.246888936421177 -9.961999999999598e-10 6.153305829757593e-11 -6.176777584579242 -9.979999999999591e-10 4.468108413921696e-11 -4.477062538999879 -9.947999999999602e-10 7.193048588018595e-11 -7.230647957397348 -9.97199999999959e-10 5.28461781372034e-11 -5.2994562913362975 -9.937999999999603e-10 7.850345571063699e-11 -7.899321363517821 -9.945999999999604e-10 7.329334473795642e-11 -7.369127763720022 -9.929999999999611e-10 8.338099590491582e-11 -8.39687773463435 +r_4537 2-phosphoglycolate exchange -9.843999999999634e-10 1.5543960979898095e-10 -15.790289496036843 -9.907999999999615e-10 1.1797518225764695e-10 -11.907063207272056 -9.86799999999963e-10 1.3201986914539356e-10 -13.378584226327373 -9.92599999999961e-10 9.458873826138534e-11 -9.529391321921125 -9.831999999999643e-10 1.3312138919366014e-10 -13.539604271121336 -9.799999999999654e-10 1.6614909299849138e-10 -16.95398908147931 -9.799999999999654e-10 1.5876095555331648e-10 -16.20009750544103 -9.804175140616411e-10 1.5985341514156362e-10 -16.30462663598575 -9.787999999999654e-10 1.6479074973505404e-10 -16.835998133945626 +r_4538 6-phospho-D-gluconate exchange -4.828000000000199e-10 5.025481777244697e-10 -104.0903433563482 -3.708000000000115e-10 4.838948138161625e-10 -130.50021947576792 -6.088000000000294e-10 4.89295863551291e-10 -80.37054263325683 -2.9260000000000564e-10 4.5631884179493244e-10 -155.95312433182627 -6.326000000000312e-10 4.838016668125005e-10 -76.4782906753836 -3.942000000000133e-10 4.932088918523364e-10 -125.11641092144085 -5.344000000000236e-10 5.004665157097766e-10 -93.65017135287324 -4.98600000000021e-10 5.01246735309007e-10 -100.530833395304 -4.800000000000195e-10 5.01647615429399e-10 -104.50991988112052 +r_4539 D-mannose 6-phosphate exchange 2.3194130204915628e-05 0.000669255353331 2885.4513940306406 3.265490856131297e-05 0.0008158061033132 2498.2648528368068 2.3843752877335635e-05 0.0009732128013398 4081.625935089087 7.260079545917821e-05 0.0019391735540654 2671.008687715805 4.688281250749917e-05 0.0023438471258858 4999.373972094562 2.8662803916527123e-05 0.0014330181655545 4999.574255637427 0.0002114054902773 0.0060997026897111 2885.3094977374512 5.347949754989771e-05 0.0037813888095808 7070.726133978259 5.137453425074624e-05 0.0036325592970555 7070.739131815661 +r_4540 2',3'-cyclic GMP exchange -9.825999999999643e-10 1.3675152721648878e-10 -13.91731398498817 -8.819999999999993e-10 3.2387803166605356e-10 -36.72086526826006 -9.849999999999634e-10 1.2481232159976992e-10 -12.671301685256298 -9.827999999999644e-10 1.3002900256597468e-10 -13.230464241552644 -9.813999999999648e-10 1.3659345355583708e-10 -13.918224328086612 -9.843999999999634e-10 1.2868547699876155e-10 -13.07247836232896 -9.876515892413704e-10 1.1384303916173764e-10 -11.52663959657901 -9.87199999999963e-10 1.2099209816167402e-10 -12.25608773923 -9.839646114485368e-10 1.4295567053471267e-10 -14.528537802214396 +r_4541 O(4)-phospho-L-tyrosine exchange -9.91399999999961e-10 9.448717143142971e-11 -9.530680999741111 -9.939999999999606e-10 7.723466215766028e-11 -7.770086736183435 -9.871999999999624e-10 1.1242191840361123e-10 -11.387957698907565 -9.89599999999962e-10 1.0145885264360168e-10 -10.252511382741064 -9.85999999999963e-10 1.175021759469603e-10 -11.917056384073495 -9.92199999999961e-10 8.798129427115769e-11 -8.867294322834223 -9.86799999999963e-10 1.1414186643442392e-10 -11.566869318446312 -9.871796767822754e-10 1.2978561367292435e-10 -13.147111587220092 -9.848837359253126e-10 1.2532869978939844e-10 -12.725227884045651 +r_4542 O-phospho-L-threonine exchange -9.98199999999959e-10 4.239244536335352e-11 -4.246888936421084 -9.989999999999588e-10 3.16101224288684e-11 -3.164176419306276 -9.957999999999599e-10 6.4677636315256e-11 -6.495042811333462 -9.975999999999592e-10 4.8935865618057365e-11 -4.905359424424556 -1.0128651879937135e-09 1.222688456904982e-09 -120.71581404894434 -9.959999999999598e-10 6.312524819271773e-11 -6.33787632457031 -9.967999999999596e-10 5.6483608946456526e-11 -5.6664936744039744 -9.9559999999996e-10 6.619302307087072e-11 -6.648555953281778 -9.931999999999608e-10 8.218948243056815e-11 -8.27521973727058 +r_4543 3-phosphonato-D-glycerate(3-) exchange -5.92600000000028e-10 4.938360201554389e-10 -83.33378672889225 -4.942000000000208e-10 5.028090327198551e-10 -101.74201390526794 -5.820000000000274e-10 4.957067127132812e-10 -85.17297469299963 -4.890000000000202e-10 5.007286149494374e-10 -102.39848976470684 -7.188000000000377e-10 4.5096256324298645e-10 -62.73825309445782 -4.97200000000021e-10 5.03232360407927e-10 -101.21326637327148 -6.46000000000032e-10 4.80760050383988e-10 -74.42106043095418 -5.816000000000271e-10 4.953690726151703e-10 -85.17349941801015 -4.8460000000002e-10 5.037991690351995e-10 -103.96185906627706 +r_4544 adenosine 2'-phosphate exchange -4.908000000000206e-10 5.047438095337522e-10 -102.84103698731276 -5.698000000000251e-10 5.480766712856073e-10 -96.1875519981719 -4.3720000000001644e-10 4.997060147929552e-10 -114.29689267907968 -4.5480000000001775e-10 4.992061711960975e-10 -109.76388988480166 -4.830000000000197e-10 5.041446542079877e-10 -104.37777519833688 -6.332000000000313e-10 4.881653624379878e-10 -77.09497195798541 -4.948000000000209e-10 5.055928053453593e-10 -102.18124602775625 -5.112000000000221e-10 5.066812658674393e-10 -99.11605357343844 -5.64600000000026e-10 4.990758011876326e-10 -88.39458044413918 +r_4545 3'-AMP exchange -9.9559999999996e-10 7.734233231079549e-11 -7.768414253796564 -9.9559999999996e-10 6.619302307087069e-11 -6.648555953281776 -9.9539999999996e-10 7.334791055781481e-11 -7.368687016055632 -9.979999999999591e-10 4.468108413921793e-11 -4.477062538999975 -9.961999999999598e-10 7.607047616170677e-11 -7.6360646618861505 -9.967999999999596e-10 5.6483608946455285e-11 -5.666493674403849 -9.929999999999611e-10 9.461918705057958e-11 -9.528619038326616 -9.927999999999604e-10 9.354095350164462e-11 -9.42193326970672 -9.92599999999961e-10 1.0073365601371979e-10 -10.148464236724136 +r_4546 2',3'-cyclic AMP exchange -6.138000000000297e-10 4.885665762819576e-10 -79.59703100064097 -5.080000000000216e-10 5.524464131550265e-10 -108.7492939281502 -6.446000000000321e-10 4.795172857838047e-10 -74.3898985081882 -6.138000000000298e-10 4.8733670025134e-10 -79.39666019083033 -6.668000000000334e-10 4.739437567232171e-10 -71.07734803887121 -9.725999999999679e-10 1.8070907878197086e-10 -18.57999987476628 -6.212000000000303e-10 4.867832696286165e-10 -78.36176265753268 -7.752000000000367e-10 4.208329598261147e-10 -54.28701752142607 -8.987999999999934e-10 3.05576889582777e-10 -33.99831882318416 +r_4547 D-mannose 1-phosphate exchange -1.1603536821812428e-10 5.10673770902807e-10 -440.1018230431588 -9.965698439872246e-11 8.692722911273565e-10 -872.2642937392557 -9.689831308652207e-11 7.839129646120624e-10 -809.0057913723368 -5.597199396786791e-11 1.18681387629934e-09 -2120.3709072445404 -1.61690981979324e-10 5.710821215755062e-10 -353.1935514180577 -1.0743615877466196e-10 6.437800621863264e-10 -599.2210346393708 -1.1702504188947172e-10 6.195634683699306e-10 -529.4281107415443 -9.580680154019336e-11 6.886642251052802e-10 -718.8051516534225 -6.854788952382632e-11 6.427387963352365e-10 -937.6492854850468 +r_4548 AMP exchange -4.228000000000153e-10 4.952668148014597e-10 -117.13973860015174 -3.0880000000000683e-10 4.6247739087162125e-10 -149.7659944532419 -4.228000000000153e-10 4.940536183407357e-10 -116.85279525560972 -2.612000000000033e-10 4.3933263324334494e-10 -168.19779220648527 -4.71200000000019e-10 5.000205636899557e-10 -106.11641844013916 -3.629919527971885e-10 8.388983535281931e-10 -231.10659811153 -4.6300000000001846e-10 4.990799697075026e-10 -107.79265004481267 -5.67600000000026e-10 4.96265549780743e-10 -87.43226740322763 -3.34006637341136e-10 9.29210608773331e-10 -278.20124060118195 +r_4549 N(alpha)-acetyl-L-methionine exchange -9.96999999999959e-10 6.776369517430939e-11 -6.79675979682168 -9.989999999999588e-10 3.1610122428867234e-11 -3.16417641930616 -9.883999999999624e-10 1.4376916886030082e-10 -14.545646384086028 -9.86799999999963e-10 1.4909797463817632e-10 -15.109239424217868 -9.86999999999963e-10 1.4434391928102007e-10 -14.624510565453445 -9.957999999999599e-10 8.113985910356968e-11 -8.148208385576716 -9.871999999999624e-10 1.4913285393106748e-10 -15.106650519760242 -9.83599999999964e-10 1.5917319881639408e-10 -16.182716431110197 -9.823999999999643e-10 1.6029778250435878e-10 -16.31695668814786 +r_4550 L-Methionine S-oxide exchange 1.232174573116194e-05 0.0003402902063166 2761.7044998427714 6.590684161332e-06 0.0002350835812313 3566.907099122712 2.5628860747105333e-06 0.000181289575972 7073.64942051011 1.463708301913543e-05 0.0005173773649917 3534.7026748113053 7.560643698295802e-06 0.0005346829358206 7071.923465208697 2.1668467358894745e-05 0.0008844740882712 4081.8488618587658 1.1364984639942845e-05 0.0008036905545142 7071.637841811412 1.7249658594185322e-05 0.0012198028653453 7071.46091434231 1.6570698178591908e-05 0.0011717933400596 7071.478385705558 +r_4551 3-sulfino-L-alanine exchange -1.1506084615745578e-10 5.50499430750597e-10 -478.4420149294421 -8.162000000000225e-10 3.8735974173098165e-10 -47.45892449534072 -6.939599999793465e-11 2.541597816793609e-10 -366.24557854476495 -1.4739999999999928e-10 3.5453967292240726e-10 -240.52895042225845 -8.020000000000059e-11 2.7162974163980264e-10 -338.6904509224447 -1.0380000000000068e-10 3.0568652055622655e-10 -294.49568454356904 -1.3419600000036264e-10 3.4148914558328925e-10 -254.47043546928856 -8.020000000000059e-11 2.7236518969814984e-10 -339.6074684515559 -7.559599997191394e-11 2.6438476629771155e-10 -349.73380389959533 +r_4552 N-acetyl-L-cysteine exchange -9.63999999999971e-10 2.590703060651527e-10 -26.874513077298808 -8.75127751983169e-10 7.343742481523357e-10 -83.91623354283249 1.0082464972548255e-10 8.647089803454582e-10 857.6364834391393 -7.375923140577744e-10 6.318404436217813e-10 -85.66255797132538 7.298857607385357e-11 9.162850664894271e-10 1255.3814799213003 -9.46399999999977e-10 3.167761187682601e-10 -33.47169471346871 -3.5155130379251025e-11 8.974470258286607e-10 -2552.819506419309 -2.0399094289570875e-10 8.672383163897261e-10 -425.1356967515492 -7.000000000000035e-11 8.121772752209293e-10 -1160.2532503156078 +r_4553 L-cysteate exchange -1.0001761538482852e-10 4.289637595828689e-10 -428.8882092743211 -9.279599999491794e-11 2.9225684800935285e-10 -314.9455235412718 -6.520000000000025e-11 2.4690312316868686e-10 -378.6857717311133 -7.960000000000057e-11 2.7070001052666703e-10 -340.0753901088757 -7.380000000000045e-11 2.6147128608451693e-10 -354.2971356158744 -9.617599994521724e-11 2.990259862526905e-10 -310.91539097385885 -1.2039600000046835e-10 3.2608917493982577e-10 -270.84718341021073 -7.479999997987767e-11 2.646109669609901e-10 -353.7579773157413 -6.98000000002109e-11 2.5640028904272855e-10 -367.33565765322913 +r_4554 2-hydroxyethane-1-sulfonate exchange -3.599999999999991e-11 1.884438967450162e-10 -523.4552687361574 -6.473599999802383e-11 1.0871697742007074e-09 -1679.3897896593776 -3.7348800588212636e-11 1.165781800392544e-09 -3121.336648118406 -7.480041268075527e-11 2.6537041939661516e-10 -354.7713306465353 -2.080761267985041e-11 1.4560914855622008e-10 -699.7878651269996 -1.457000000021042e-11 1.4225421734212764e-10 -976.3501533292604 -2.6975982300591942e-11 1.6333465299983468e-10 -605.4817621831351 -1.5883400000000048e-11 2.0038893819207544e-10 -1261.6249555641414 -1.5971799999999392e-11 1.847973003406962e-10 -1157.0223790725106 +r_4555 acetoacetate exchange 1.3391067593204098e-06 9.472434010544936e-05 7073.695913051885 8.01637453007641e-06 0.0002839582285795 3542.227568263152 1.0304445133064496e-05 0.0003283491910562 3186.4810459577247 3.225646806643466e-06 0.0002281377026532 7072.6188057340205 2.474567589349005e-05 0.0008780452652187 3548.2775616960416 8.57224795105624e-06 0.0004345205553682 5068.9219193046565 4.707213907896953e-05 0.0014922659400237 3170.168106276771 4.238285430611216e-05 0.0017342238731485 4091.805286692201 4.748195715921013e-05 0.0017244649920338 3631.832163639716 +r_4556 N-acetyl-L-glutamate exchange 1.666626156372661e-05 0.000480902268614 2885.4837467612606 2.276493629346412e-05 0.0006568584769452 2885.39562983012 5.94523359130001e-05 0.0014009232085198 2356.3804298116765 5.750573727611226e-05 0.0016592405571963 2885.34785534444 8.207748387081406e-05 0.0028077152917386 3420.8106283544253 6.158131330608041e-05 0.0017769630473634 2885.5556206333054 0.0002433796230455 0.0059619636370641 2449.6560404108013 0.0002259579600833 0.0071425866840201 3161.024591204643 0.0002165524021892 0.0068453439474746 3161.056574884368 +r_4557 UMP exchange 1.7808831081674335e-05 0.0003360684030464 1887.088498426584 3.29806564259865e-05 0.0006224187887636 1887.2237736092643 2.908881677850388e-05 0.0006498559524465 2234.040515964736 4.4705111019477147e-05 0.0009642194695754 2156.8439213926345 0.0001546465118171 0.0025731604936029 1663.8981787353096 7.041468890540463e-05 0.0012838320414956 1823.2446403624167 9.049938580256584e-05 0.0024171980064178 2670.9551506694006 0.0003497759768242 0.0058251443543279 1665.3929201248022 0.0002966747629025 0.0052444394117617 1767.7403229221309 +r_4558 CMP exchange -6.048000000000291e-10 4.913911405902872e-10 -81.24853515050654 -4.4900000000001727e-10 5.018459622971745e-10 -111.76970207063592 -4.5837378322213755e-10 4.995466152582904e-10 -108.9823706204854 -3.46580125476455e-10 4.767909998517914e-10 -137.57020810017065 -5.332000000000238e-10 5.017450643722457e-10 -94.10072475097962 -3.474000000000097e-10 4.78705621247919e-10 -137.79666702587957 -4.186000000000151e-10 4.962089123110696e-10 -118.54011283111608 -5.324000000000234e-10 5.025940311544029e-10 -94.40158361276872 -4.3520000000001624e-10 4.95832764171569e-10 -113.932160885007 +r_4559 thymidine 5'-monophosphate exchange -9.912890608701722e-10 1.3386751156148603e-10 -13.50438704972438 -9.9419999999996e-10 8.104118418869972e-11 -8.15139651867863 -9.9419999999996e-10 8.583608545776783e-11 -8.633683912469447 -9.933999999999606e-10 8.807946184168347e-11 -8.86646485219317 -9.90199999999962e-10 1.1183229091929691e-10 -11.293909404090204 -9.945999999999604e-10 7.329334473795692e-11 -7.369127763720072 -9.911999999999614e-10 1.0161016152426001e-10 -10.251226949582724 -9.883999999999624e-10 1.1431558778539967e-10 -11.565721143808585 -9.917999999999614e-10 9.661587305088408e-11 -9.741467337254267 +r_4560 thymidine 3'-monophosphate exchange -9.933999999999606e-10 9.251027851177855e-11 -9.312490287072904 -9.9539999999996e-10 7.334791055781635e-11 -7.368687016055786 -9.939999999999606e-10 8.697995805138615e-11 -8.750498797926518 -9.9419999999996e-10 8.347307081155456e-11 -8.396003903797816 -9.91599999999961e-10 9.965654160794639e-11 -10.05007478902282 -9.939999999999606e-10 7.723466215766139e-11 -7.770086736183547 -9.91399999999961e-10 1.0260675235638507e-10 -10.349682505183484 -9.90199999999962e-10 1.0443247209678831e-10 -10.546603928175353 -9.91599999999961e-10 9.96565416079462e-11 -10.0500747890228 +r_4561 cytidine 2'-phosphate exchange -9.84199999999964e-10 1.2630736601696182e-10 -12.833505996440405 -9.243999999999847e-10 2.6513901964807457e-10 -28.682282523591407 -9.805999999999652e-10 1.4222406806553116e-10 -14.503780141294738 -9.82999999999964e-10 1.2928396214757067e-10 -13.151979872591593 -9.727554932992124e-10 1.6297842458920267e-10 -16.75430524030685 -9.81199999999965e-10 1.4160003571334622e-10 -14.431312241474858 -9.677786321217748e-10 1.779209629856534e-10 -18.384469038707373 -9.759999999999664e-10 1.5436568839334196e-10 -15.816156597679017 -9.847999999999638e-10 1.2558707904431954e-10 -12.752546612949246 +r_4562 uridine 2'-phosphate exchange -1.5654626218051433e-10 3.8383992738924225e-10 -245.1926491522579 -1.8507663824327447e-10 4.193079614678973e-10 -226.5590975975784 -1.4531729095579036e-10 3.976592285072572e-10 -273.6489414932986 -1.6348168336168478e-10 3.9344271066809286e-10 -240.66470480221645 -2.0298077219163395e-10 4.244341273544049e-10 -209.1006565654885 -2.189542356706696e-10 4.2692721469158767e-10 -194.98467950797337 -2.2605726425373692e-10 4.49012995360922e-10 -198.62798784334987 -2.1155884348535686e-10 4.262569583422993e-10 -201.48387622085053 -1.5424070040359224e-10 4.1537821156092327e-10 -269.3051901826356 +r_4563 3'-UMP exchange -1.2694766591614288e-10 3.797820863592739e-10 -299.1642923235346 -1.2011365659561732e-10 4.1355555146885614e-10 -344.30352317152415 -1.1901409783803696e-10 3.691230059412273e-10 -310.1506566420029 -1.240532471588931e-10 3.9841474231915397e-10 -321.1642995598866 -1.2859208212427884e-10 4.598475709363866e-10 -357.60177713894035 -9.823690647512016e-11 5.647028832525162e-10 -574.8378114853759 -1.0722066807942503e-10 3.5807485364541947e-10 -333.9606626776203 -1.4715824491764978e-10 4.5896544046153077e-10 -311.88564440841844 -1.2437884849000949e-10 3.7973123144568805e-10 -305.3020960201198 +r_4564 2',3'-cyclic CMP exchange 3.247419097781949e-11 2.3447426291260403e-10 722.0326537857543 3.3841404334121894e-11 2.767023460664985e-10 817.6443960025107 3.661025910639524e-12 1.9930580415100827e-10 5443.987806035295 2.920154183669179e-11 3.8311841701796727e-10 1311.9800973542376 2.7538095136696112e-11 3.036966270010106e-10 1102.8236539001468 5.1684449098917145e-11 3.0468149871138556e-10 589.503233609525 9.340000000000087e-11 3.8510531185669826e-10 412.3183210457116 9.000000000000004e-12 3.0089384743043257e-10 3343.264971449249 2.1626220100336966e-10 4.4390283244591566e-10 205.26140508437675 +r_4565 2',3'-cyclic UMP exchange 2.239999999999997e-11 1.7973508544573203e-10 802.3887743113048 3.456210650481987e-11 2.5929576720514856e-10 750.2313759984172 2.877874136949285e-11 2.673304961092192e-10 928.9165661449152 3.502686372475657e-11 2.9195430376530385e-10 833.515401377355 3.0010936043608166e-11 3.80886121367418e-10 1269.1577524071945 1.06991528592115e-10 3.7438288178311976e-10 349.91824746273494 1.1405389454283527e-10 4.1128173307132405e-10 360.60297170900975 6.030289127115016e-11 3.9346664075299007e-10 652.4838734245411 2.922055911345865e-11 3.10268489337119e-10 1061.815717257145 +r_4567 6-phosphogluconate phosphatase 5.9047958677800894e-05 0.0020869585411333 3534.3449424237506 0.000134381704734 0.0042478245309608 3161.0140229785925 4.541622392202548e-05 0.0022705883794928 4999.509389840906 0.0001677128529596 0.0053014222001291 3161.011280038375 0.0001339471946322 0.0066967148056557 4999.518522236217 0.0001094416663933 0.0054715366246914 4999.500469069548 0.0003020082184388 0.0123269724157386 4081.667869655395 0.0006111647022523 0.0216014564624948 3534.4738305217534 0.0002935551536598 0.0146762944616657 4999.501551476695 +r_4569 Carboxylic ester hydrolases 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4570 phosphoglycerate dehydrogenase -0.0038519134706342 0.0040484465175188 -105.10221863452728 -0.0059148136324935 0.0023725616786337 -40.11219669880799 -0.0161340180423036 0.0048873891780413 -30.29244894375671 -0.0265081349499242 0.0065823821203438 -24.831555040663844 -0.0295479531670378 0.0128404330028318 -43.4562520464396 -0.0411459920289206 0.0146964563930335 -35.717832207578724 -0.0480236573169008 0.0202565243533454 -42.18030338604935 -0.0608121846122969 0.0288183011288764 -47.38902460519243 -0.0641567571368071 0.0281080320303853 -43.81149123614232 +r_4571 seed:rxn00681 0.0038519134706342 0.0040484465175188 105.10221863452728 0.0059148136324935 0.0023725616786337 40.11219669880799 0.0161340180423036 0.0048873891780413 30.29244894375671 0.0265081349499242 0.0065823821203438 24.831555040663844 0.0295479531670378 0.0128404330028318 43.4562520464396 0.0411459920289206 0.0146964563930335 35.717832207578724 0.0480236573169008 0.0202565243533454 42.18030338604935 0.0608121846122969 0.0288183011288764 47.38902460519243 0.0641567571368071 0.0281080320303853 43.81149123614232 +r_4572 beta-alanine:2-oxoglutarate aminotransferase 6.41972750450461e-05 0.0006796923455019 1058.755757195274 0.0001012309863397 0.0011640816008226 1149.9261667917672 8.282426147335799e-05 0.0009606007174718 1159.8059558681623 0.0001186699143223 0.0013500446373276 1137.646930173322 0.0002847321740135 0.0030179661512948 1059.9315520806138 0.0002379257066304 0.0026016313339446 1093.4637415980485 0.0003242942107965 0.0039439152503461 1216.1534554253908 0.0005769162388471 0.0065214552384759 1130.3989729093787 0.0005878831463807 0.0064687056838205 1100.33868527172 +r_4573 3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) 4.981133041682545e-06 0.0002033132055601 4081.665835037324 1.198372131891267e-05 0.0004236251821643 3535.00528667824 1.1706532119177162e-06 8.277768245648889e-05 7071.067811865982 1.1021005008781552e-05 0.0004498406159325 4081.666014796972 1.1625119908254715e-05 0.0006007984061851 5168.105025381336 3.555891574933348e-06 0.0002514394762715 7071.067015767125 9.914694672447113e-06 0.00049624294075 5005.125797056434 3.335143550786441e-05 0.0016674049364956 4999.499754973035 1.2820103803412952e-05 0.0006409412593468 4999.501323665093 +r_4574 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 5.771443005328483e-05 0.0006404163865613 1109.6295778544736 8.924720519649677e-05 0.0010852498079553 1216.0042497307516 7.649841804028195e-05 0.0009256314744271 1210.000805428038 0.0001056349506511 0.001266010689163 1198.4770962249852 0.0002664964924822 0.0029220777715754 1096.4788858411691 0.000228548147957 0.0025573684593472 1118.962670320198 0.0003044430771776 0.003850562636829 1264.7890280594436 0.0005435648033393 0.0063075671848242 1160.4075808578016 0.0005609928713359 0.0063619208032596 1134.0466391505709 +r_4575 3-oxopropanoate carboxy-lyase 1.5017119500785702e-06 0.0001061870703289 7071.067811866142 5.9824377523787e-11 4.462282403434991e-09 7458.970052234518 5.155190221158319e-06 0.0002290910384661 4443.891081378024 2.013958662395548e-06 0.00014240689911 7070.9941454646 6.610561623032173e-06 0.0004674372951097 7071.067811865312 5.821667098472737e-06 0.000411654028314 7071.067811865204 9.936438946435244e-06 0.0007026125509597 7071.069975343345 0.0 0.0 1.4070171241436305e-05 0.0009949113497275 7071.067811865464 +r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.0038305615340554 0.0040168849105479 104.86412696509488 0.0058684812014693 0.0021945477815619 37.39549819146462 0.0161071417007227 0.0048370494365062 30.030464289571707 0.0264370122080306 0.0064214042941121 24.28944785281595 0.0294421582232592 0.0126029327024309 42.80573661367904 0.0410852291936682 0.0145990087950146 35.53347293305237 0.0478425786065382 0.0198727486327411 41.53778749297036 0.0606184275056487 0.0283703851051721 46.801585380169136 0.0639234772014215 0.0275976939182151 43.17301737396947 +r_4582 malate/beta-methylmalate synthase 0.0038305615340554 0.0040168849105479 104.86412696509488 0.0058684812014693 0.0021945477815619 37.39549819146462 0.0161071417007227 0.0048370494365062 30.030464289571707 0.0264370122080306 0.0064214042941121 24.28944785281595 0.0294421582232592 0.0126029327024309 42.80573661367904 0.0410852291936682 0.0145990087950146 35.53347293305237 0.0478425786065382 0.0198727486327411 41.53778749297036 0.0606184275056487 0.0283703851051721 46.801585380169136 0.0639234772014215 0.0275976939182151 43.17301737396947 +r_4583 palmitoyl-CoA hydrolase 7.965133984210597e-05 0.0018759017535165 2355.14149195122 0.0001128810552503 0.0030150524392189 2670.999515845996 8.174929093533346e-05 0.0023587182757105 2885.3073203733725 0.0001811457024804 0.0042662259818345 2355.1350782365625 0.0002394937610262 0.0069109145936455 2885.634500052403 0.0001641625128267 0.0051891971286838 3161.012242887461 0.0004228115692535 0.0112933310483189 2671.008049343614 0.0004567616047258 0.0144386502789678 3161.0910657946188 0.0004387206829895 0.0138683893321081 3161.0976801011857 +r_4584 long-chain-fatty-acid---CoA ligase 7.965133984210597e-05 0.0018759017535165 2355.14149195122 0.0001128810552503 0.0030150524392189 2670.9995158459965 8.174929093533346e-05 0.0023587182757105 2885.3073203733725 0.0001811457024804 0.0042662259818345 2355.1350782365625 0.0002394937610262 0.0069109145936455 2885.6345000524025 0.0001641625128267 0.0051891971286838 3161.012242887461 0.0004228115692535 0.0112933310483189 2671.008049343614 0.0004567616047258 0.0144386502789678 3161.0910657946188 0.0004387206829895 0.0138683893321081 3161.0976801011857 +r_4585 a-galactosidase (stachyose) 8.100000000000246e-10 4.0191081903987166e-10 49.61861963455053 5.768000000000258e-10 5.951240160831217e-10 103.17684051371276 9.217999999999855e-10 2.816036578669209e-10 30.549322832168063 8.672000000000061e-10 3.622021508489462e-10 41.76685318830069 8.072000000000254e-10 4.1528622964230335e-10 51.44774896460484 3.864000000000125e-10 5.023400333457707e-10 130.00518461329048 6.957096411299646e-10 5.130533274715696e-10 73.74532378741702 7.082000000000362e-10 4.873399840481153e-10 68.81389212766035 8.096000000000244e-10 4.01223174813209e-10 49.558198470009486 +r_4586 stachyose synthase -4.3599999999999874e-11 2.1096905362710101e-10 -483.8739762089487 -2.959999999999993e-11 2.1710197293745015e-10 -733.4526112751712 -1.6529999999999875e-10 3.772987952222912e-10 -228.25093479872595 -5.6000000000000046e-11 2.4428658413231636e-10 -436.2260430934217 -1.7419999999999848e-10 3.8766534134915716e-10 -222.54037964934588 -3.159999999999993e-11 2.1403411438466576e-10 -677.3231467869186 -1.8699999999999806e-10 4.075097702418491e-10 -217.9196632309376 -4.268000000000157e-10 4.994913996573568e-10 -117.03172438081968 -6.260000000000019e-11 2.5356281040357605e-10 -405.0524127852641 +r_4587 Ca(2+) transport 4.929390610630358e-06 3.642110129103328e-08 0.7388560608788078 8.030757855931628e-06 4.9545049458283944e-08 0.6169411448720159 1.8649136601384257e-05 5.2544987203505453e-08 0.2817556025602022 2.772243470906083e-05 7.505409779093951e-08 0.2707341493581325 3.908906610885928e-05 1.6458277314974548e-07 0.4210455493907128 4.632969784687849e-05 1.3494099752414873e-07 0.2912624165392447 5.1868093967778415e-05 2.450596806277535e-07 0.4724671023770216 6.09140828923048e-05 3.575884965999295e-07 0.5870374790541305 6.906897721769432e-05 3.477369474231457e-07 0.5034632934075954 +r_4588 chloride transport 2.9303750634624144e-05 2.165125376287406e-07 0.7388560608788352 4.7740449926967496e-05 2.945304783464878e-07 0.6169411448720223 0.0001108635309483 3.123642096429367e-07 0.2817556025602023 0.0001648015703902 4.461741297249114e-07 0.2707341493581234 0.0002323727893106 9.783952873878329e-07 0.4210455493907543 0.0002754161761404 8.021838101665574e-07 0.2912624165391871 0.0003083402821126 1.4568063963584725e-06 0.4724671023769456 0.0003621159766408 2.125756500524765e-06 0.5870374790541791 0.000410594380695 2.067191991593954e-06 0.5034632934076742 +r_4589 Cu2(+) transport 1.496990051799742e-05 1.1060601728475865e-07 0.7388560608788522 2.4388338373542254e-05 1.5046169397700548e-07 0.6169411448720681 5.6634935577474535e-05 1.5957210399589096e-07 0.2817556025601938 8.418932936992207e-05 2.2792926471994614e-07 0.2707341493580983 0.0001187082698881 4.998158871229603e-07 0.4210455493907475 0.0001406971008345 4.097977758913144e-07 0.2912624165392151 0.0001575164696993 7.442135001552845e-07 0.472467102377076 0.0001849879291521 1.0859484758494769e-06 0.587037479054182 0.0002097532533938 1.0560306375661771e-06 0.5034632934075881 +r_4590 Mn(2+) transport 6.201491413373763e-05 4.582009517259397e-07 0.7388560608788574 0.0001010321149617 6.233086867332277e-07 0.6169411448720792 0.0002346181701464 6.610498390118012e-07 0.2817556025602278 0.0003487661140817 9.442289722085624e-07 0.2707341493581187 0.0004917656704018 2.0705574686580366e-06 0.421045549390683 0.0005828574890414 1.69764480756181e-06 0.2912624165392189 0.0006525340854011 3.083008885316726e-06 0.4724671023769492 0.0007663384621935 4.498693989482743e-06 0.5870374790540945 0.000868932294029 4.37475514500115e-06 0.5034632934076185 +r_4591 Zn(2+) transport 1.6991592735230988e-05 1.2554450088114478e-07 0.7388624647343167 2.7682059141643995e-05 1.7078205563210005e-07 0.6169413003499478 6.428267536663662e-05 1.8113567074275682e-07 0.2817799192545244 9.555834357959102e-05 2.587259972716056e-07 0.2707518648605618 0.000134739812312 5.673212039036744e-07 0.4210494241966138 0.0001596985194871 4.651474345818307e-07 0.2912659654426415 0.0001787886917117 8.447259284696907e-07 0.472471676134721 0.0002099701398062 1.2326096294888409e-06 0.5870404385244502 0.0002380807033218 1.1986366790567366e-06 0.5034581393336406 +r_4592 Mg(2+) transport 2.8225671735994728e-05 2.085514846851806e-07 0.7388716436435622 4.598415587251513e-05 2.836952208842828e-07 0.6169412387840489 0.0001067840595419 3.0088206180255386e-07 0.28176683214075 0.0001587378093215 4.29765088608071e-07 0.2707389565503551 0.0002238234100835 9.42408132191516e-07 0.4210498498971097 0.0002652838964853 7.726732527526503e-07 0.2912627803607713 0.0002969960517876 1.4032185485105145e-06 0.4724704386015647 0.0003487934029241 2.047544807871016e-06 0.5870365639674473 0.0003954888978891 1.9911332080762894e-06 0.503461214386468 +r_4593 chloride exchange -2.9303750634624144e-05 2.165125376287406e-07 -0.7388560608788352 -4.7740449926967496e-05 2.945304783464878e-07 -0.6169411448720223 -0.0001108635309483 3.123642096429368e-07 -0.2817556025602024 -0.0001648015703902 4.461741297249114e-07 -0.2707341493581234 -0.0002323727893106 9.783952873878329e-07 -0.4210455493907543 -0.0002754161761404 8.021838101665574e-07 -0.2912624165391871 -0.0003083402821126 1.4568063963584725e-06 -0.4724671023769456 -0.0003621159766408 2.125756500524765e-06 -0.5870374790541791 -0.000410594380695 2.067191991593954e-06 -0.5034632934076742 +r_4594 Cu2(+) exchange -1.496990051799742e-05 1.1060601728475865e-07 -0.7388560608788522 -2.4388338373542254e-05 1.5046169397700548e-07 -0.6169411448720681 -5.6634935577474535e-05 1.5957210399589096e-07 -0.2817556025601938 -8.418932936992207e-05 2.2792926471994614e-07 -0.2707341493580983 -0.0001187082698881 4.998158871229603e-07 -0.4210455493907475 -0.0001406971008345 4.097977758913144e-07 -0.2912624165392151 -0.0001575164696993 7.442135001552845e-07 -0.472467102377076 -0.0001849879291521 1.0859484758494769e-06 -0.587037479054182 -0.0002097532533938 1.0560306375661771e-06 -0.5034632934075881 +r_4595 Mn(2+) exchange -6.201491413373763e-05 4.582009517259396e-07 -0.7388560608788574 -0.0001010321149617 6.233086867332277e-07 -0.6169411448720792 -0.0002346181701464 6.610498390118012e-07 -0.2817556025602278 -0.0003487661140817 9.442289722085624e-07 -0.2707341493581187 -0.0004917656704018 2.0705574686580366e-06 -0.421045549390683 -0.0005828574890414 1.6976448075618095e-06 -0.2912624165392189 -0.0006525340854011 3.083008885316725e-06 -0.4724671023769491 -0.0007663384621935 4.498693989482743e-06 -0.5870374790540945 -0.000868932294029 4.37475514500115e-06 -0.5034632934076185 +r_4596 Zn(2+) exchange -1.6991592735230988e-05 1.2554450088114478e-07 -0.7388624647343167 -2.7682059141643995e-05 1.7078205563210005e-07 -0.6169413003499478 -6.428267536663662e-05 1.8113567074275682e-07 -0.2817799192545244 -9.555834357959102e-05 2.587259972716056e-07 -0.2707518648605618 -0.000134739812312 5.673212039036744e-07 -0.4210494241966138 -0.0001596985194871 4.651474345818307e-07 -0.2912659654426415 -0.0001787886917117 8.447259284696907e-07 -0.472471676134721 -0.0002099701398062 1.2326096294888409e-06 -0.5870404385244502 -0.0002380807033218 1.1986366790567366e-06 -0.5034581393336406 +r_4597 Mg(2+) exchange -2.8225671735994728e-05 2.085514846851806e-07 -0.7388716436435622 -4.598415587251513e-05 2.836952208842828e-07 -0.6169412387840489 -0.0001067840595419 3.0088206180255386e-07 -0.28176683214075 -0.0001587378093215 4.29765088608071e-07 -0.2707389565503551 -0.0002238234100835 9.42408132191516e-07 -0.4210498498971097 -0.0002652838964853 7.726732527526503e-07 -0.2912627803607713 -0.0002969960517876 1.4032185485105145e-06 -0.4724704386015647 -0.0003487934029241 2.047544807871016e-06 -0.5870365639674473 -0.0003954888978891 1.9911332080762894e-06 -0.503461214386468 +r_4598 cofactor pseudoreaction 0.0227160857625298 0.000167839176617 0.738856061610493 0.0370081007183586 0.000228318200315 0.6169411450011508 0.0859407216653628 0.0002421427981728 0.281755602560196 0.1277531553432387 0.0003458714179802 0.2707341490321217 0.1801339452021157 0.0007584459592154 0.4210455493907324 0.2135009117363308 0.0006218479149572 0.2912624165864283 0.2390234745059068 0.0011293072839988 0.4724671023769677 0.2807100594115241 0.0016478732562208 0.5870374790541678 0.3182902175929902 0.001602474412096 0.5034632934101514 +r_4599 ion pseudoreaction 0.0227160857632771 0.0001678391764563 0.7388560608787443 0.037008100718579 0.0002283182002685 0.6169411448720218 0.0859407216653628 0.0002421427981728 0.281755602560196 0.1277531553412949 0.0003458714183914 0.2707341493581141 0.1801339452021157 0.0007584459592154 0.4210455493907324 0.2135009117367695 0.0006218479148578 0.2912624165392366 0.2390234745059068 0.0011293072839988 0.4724671023769677 0.2807100594115241 0.0016478732562208 0.587037479054168 0.3182902175930254 0.0016024744120882 0.5034632934076538 +r_4600 Ca(2+) exchange -4.929390610630358e-06 3.642110129103328e-08 -0.7388560608788078 -8.030757855931628e-06 4.9545049458283944e-08 -0.6169411448720159 -1.8649136601384257e-05 5.2544987203505453e-08 -0.2817556025602022 -2.772243470906083e-05 7.505409779093951e-08 -0.2707341493581325 -3.908906610885928e-05 1.6458277314974548e-07 -0.4210455493907128 -4.632969784687849e-05 1.3494099752414873e-07 -0.2912624165392447 -5.1868093967778415e-05 2.450596806277535e-07 -0.4724671023770216 -6.09140828923048e-05 3.575884965999295e-07 -0.5870374790541305 -6.906897721769432e-05 3.477369474231457e-07 -0.5034632934075954 +r_4601 3-(4-hydroxyphenyl)pyruvate transport 7.597999999858374e-10 4.3421385091538607e-10 57.1484405005896 -6.759999999579642e-10 1.3713497437715564e-09 -202.8623881445017 7.143999998621776e-10 4.66557794015515e-10 65.30764195206096 -4.18999993618065e-10 1.302988305246148e-09 -310.9757339122713 5.425999981861973e-10 8.835957144364967e-10 162.84476914673414 7.333999998953862e-10 5.926168060929857e-10 80.80403683903977 -4.439999998263767e-10 1.362951036022971e-09 -306.9709541792667 -5.200000040212859e-10 1.2399626962395467e-09 -238.454362817426 2.2140000002278188e-10 5.032223033293017e-10 227.29101322381248 +r_4602 acetate transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4603 ADP-ribose transport 5.791478399999201e-10 1.2162956069228934e-09 210.0147014142472 9.605503200371424e-10 1.6271388989705143e-09 169.39652874277277 7.980927992625505e-10 5.361817178421285e-10 67.18287877519609 9.256000000003727e-10 3.0932794370282136e-10 33.41918147176932 4.1892528434365215e-10 8.567560787403429e-10 204.5128596338268 9.375951999943238e-10 3.4202499141905277e-10 36.47896143464935 9.540817999999558e-10 2.696010238318164e-10 28.25764246124692 8.9762520000013e-10 4.4315851093953266e-10 49.37010580133763 9.124193999999887e-10 3.7189834898805926e-10 40.75958369452293 +r_4604 farnesyl diphosphate transport 1.7799999999999986e-11 1.3223712539020804e-10 742.9051988213942 4e-13 1.9997999499871765e-11 4999.499874967941 2.3544999999733353e-10 4.5933973930758894e-10 195.0901419888685 2.6200000001064517e-11 2.3403955840895604e-10 893.2807572497973 1.263e-10 3.339095822551573e-10 264.37813321865195 2.3999999995692896e-12 6.815547692508196e-11 2839.8115390547227 2.0083333321044343e-10 4.020101782707662e-10 200.17104324485783 7.835000001560079e-11 3.74568869269893e-10 478.0713072052457 2.962000000000058e-10 4.566259535465685e-10 154.1613617645373 +r_4605 nicotinate transport -7.146105839810332e-10 9.942910352517923e-09 -1391.3746277205742 2.7445407851799964e-10 1.6117697635752052e-08 5872.63913977325 1.2344656893477678e-10 7.011147065516513e-10 567.9499338066549 4.6011703793200815e-10 6.379445186972913e-10 138.64831469065504 7.421979718401854e-11 3.5199596682768316e-10 474.2615584827778 8.289759828196107e-11 3.821424242622524e-10 460.98129762754365 5.880479612395132e-11 4.08459041234368e-10 694.6015770098076 1.1061088305595438e-10 4.3951025248294307e-10 397.3481092819858 5.1633016831327e-10 7.253241403302101e-10 140.476808221312 +r_4606 O-phosphoethanolamine transport -1.5247940231372595e-09 1.0712149060363538e-09 -70.25308925544789 -1.468599999999962e-09 1.0630334181057723e-09 -72.3841357827727 -1.353599999999953e-09 8.97289287584072e-10 -66.28910221513765 -1.3073999999999382e-09 9.70099715849703e-10 -74.20068195271136 -1.446999999999957e-09 1.1210005925358375e-09 -77.47066983661858 -1.4591999999999635e-09 9.126346149407871e-10 -62.54349060723754 -1.224399999999957e-09 9.067574547895147e-10 -74.05728967572252 -1.1596000000001884e-09 8.20891352447067e-10 -70.79090655803154 -1.15979999999995e-09 8.199990485896744e-10 -70.70176311344281 +r_4607 phosphate transport -0.0003657062921609 0.0051617083745027 -1411.435483924016 -0.0004833735073525 0.0080425384506706 -1663.8351768013554 -0.000475798129505 0.0073271814693176 -1539.976938736515 -0.0006023018544251 0.0100215432917429 -1663.8738894980293 -0.0012753435851283 0.0206063264240602 -1615.747055487557 -0.0013123427678808 0.0188984539039296 -1440.0547148551875 -0.0019093806845789 0.0309192497926282 -1619.3339569393297 -0.0027474757391641 0.045713703747157 -1663.843763769309 -0.0027885248038816 0.0451543371308564 -1619.2912133326506 +r_4608 propionyl-CoA transport 2.13519365788399e-05 0.0005251103017858 2459.309954611795 4.633243102422194e-05 0.0009124316337106 1969.3152583201324 2.6876341580996955e-05 0.0007129966011403 2652.8781790913067 7.112274189362333e-05 0.0014544943696011 2045.048223501616 0.0001057949437785 0.0025031369075789 2366.026974614899 6.0762835252474266e-05 0.0017280929095871 2843.996502807648 0.0001810787103626 0.0040084436761934 2213.6471306675667 0.0001937571066484 0.0051607730379062 2663.5270969798034 0.0002332799353854 0.0054467996564239 2334.8770426498286 +r_4609 UDP transport 0.0001619356873301 0.0034491449256726 2129.94737759094 0.0002687641289375 0.0060043230354354 2234.049260654924 0.0003177697018387 0.0059974722353112 1887.3644027755904 0.0003016790779635 0.0071049657391535 2355.1403654220035 0.0008735008977276 0.0170555749105466 1952.553793008797 0.0008745885485403 0.0154375485064296 1765.1212712759589 0.0010066942677192 0.0224900951373298 2234.0541571060094 0.0015279120662374 0.0341343844437009 2234.05424945417 0.0019078594803725 0.0373712718318317 1958.806307083681 +r_4610 UDP transport -0.0001070077735633 0.0027985145439626 -2615.2441554211587 -0.000245994652827 0.0057592554223823 -2341.211630494749 -0.000297272282877 0.0057385684353817 -1930.4081698580983 -0.0003248871577569 0.0073309247893407 -2256.452621874561 -0.0006944228334314 0.0152786903563725 -2200.1998812271854 -0.0006389252687445 0.0132560113272128 -2074.735806467573 -0.0013920121282819 0.0261980904107567 -1882.030327069902 -0.0010970547834219 0.0290094468624079 -2644.302481588226 -0.0018160509031527 0.0349099734816684 -1922.301485110509 +r_4611 UMP transport -0.0001619356873301 0.0034491449256726 -2129.94737759094 -0.0002687641289375 0.0060043230354354 -2234.049260654924 -0.0003177697018387 0.0059974722353112 -1887.3644027755904 -0.0003016790779635 0.0071049657391535 -2355.1403654220035 -0.0008735008977276 0.0170555749105466 -1952.553793008797 -0.0008745885485403 0.0154375485064296 -1765.1212712759589 -0.0010066942677192 0.0224900951373298 -2234.0541571060103 -0.0015279120662374 0.0341343844437009 -2234.05424945417 -0.0019078594803725 0.0373712718318317 -1958.806307083681 +r_4612 TRX1 disulphide transport 2e-13 1.4142135623729323e-11 7071.067811864661 2.000000000000001e-13 1.4142135623729262e-11 7071.067811864628 4e-13 1.9997999499869406e-11 4999.499874967351 0.0 0.0 3.2211161651269256e-22 2.2776730833508548e-20 7071.067811865471 1.6e-12 3.9971984588089084e-11 2498.249036755568 2e-13 1.4142135623730522e-11 7071.067811865261 1.6e-12 3.997198458808783e-11 2498.249036755489 6.599999999999999e-12 8.341361739136859e-11 1263.8426877480092 +r_4613 oleate transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4614 (R)-acetoin transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4615 L-glutamine transport -4.0160000000001374e-10 4.902708568767011e-10 -122.07939663264044 -2.2100000000000022e-10 4.149619725803107e-10 -187.7655984526291 -1.0160000000000071e-10 3.021517816260971e-10 -297.3934858524556 -1.3639999999999963e-10 3.4324714670446503e-10 -251.6474682584061 -4.988000000000212e-10 5.000485673551616e-10 -100.25031422516852 -1.6539999999999878e-10 3.7157832833846927e-10 -224.65437021673043 -1.4879999999999927e-10 3.559268137965338e-10 -239.19812755143525 -3.2700000000000823e-10 4.695903566094426e-10 -143.60561364202775 -7.880000000000056e-11 2.6945330025108163e-10 -341.9458125013702 +r_4616 UMP transport 1.5795738568152003e-10 9.128782645624903e-10 577.9269266984908 8.821919685549839e-11 6.02877476329893e-10 683.3858137672651 5.208783997918805e-11 5.851003100315334e-10 1123.2953992050986 1.5753969426307696e-10 6.10060660384506e-10 387.2425062383074 3.4593537171726195e-10 3.640515974159775e-10 105.23688156223648 3.615675055327621e-10 5.63883950356081e-10 155.95537257287825 1.8112647742002727e-10 6.215645637724982e-10 343.16604210830394 -1.4895703144336854e-10 5.586302303321241e-10 -375.02776802081206 5.1161439024158796e-11 5.459476258794381e-10 1067.1076425775234 +r_4617 S-adenosyl-L-methionine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4618 glutathione transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4619 ATP transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4620 D-mannose 6-phosphate transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4621 O-acetyl-L-serine transport 2.196885348476013e-05 0.0007141577466257 3250.773860917074 6.207609525749131e-05 0.0016585685626505 2671.8313318045807 3.437770600210604e-05 0.0010949749040941 3185.130805490858 5.589046058191445e-05 0.0017667096686686 3161.0218457214487 0.0001500002409445 0.0040152678520523 2676.840934900457 0.0001741381266839 0.0039241173391918 2253.4509896927148 0.0001910088901902 0.005526552306359 2893.348210574652 0.0002991874015567 0.0086423560931027 2888.609629996158 0.0001889364318791 0.0066907582380382 3541.2747935863936 +r_4622 hydrogen sulfide transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4623 L-cysteinylglycine transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4624 ATP transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4625 thiosulfate transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4626 sulphite transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4627 UDP-D-glucose transport -1.344158490033362e-10 9.734676943381326e-10 -724.2209170690661 -1.6528383862123508e-10 6.488126227385585e-10 -392.5445029295206 -2.870662677072116e-10 6.315158173853033e-10 -219.9895593547784 -1.2579468817893285e-10 9.37306072808972e-10 -745.10783116353 -1.2036464349591588e-10 6.982892991802361e-10 -580.1448655509289 8.25288322479413e-11 7.290839434358752e-10 883.4293707749181 -4.804485484749994e-10 7.16532603628025e-10 -149.13825963308338 -1.5977932275311468e-10 5.620424967425628e-10 -351.7617217660954 -3.705599784746434e-10 6.793152690359621e-10 -183.3212728023855 +r_4628 UDP-N-acetyl-alpha-D-glucosamine transport -5.29033766515183e-10 1.2720706441098292e-09 -240.45169224057867 -1.923963352742799e-10 1.1784781157006071e-09 -612.5262802020479 -1.1163380452736891e-10 1.180876275436326e-09 -1057.812443494044 -3.6197145657281255e-10 1.138756287949013e-09 -314.5983660509834 -6.98212119540426e-10 7.908919071351137e-10 -113.27387265286816 -7.207443663138676e-10 1.206339526997647e-09 -167.37411811725684 -3.724167682728049e-10 1.350141556021961e-09 -362.535114163535 2.7688535902156757e-10 1.2682621641601327e-09 458.0459467563769 4.6006359780008696e-11 1.2092788397695663e-09 2628.5036363495083 +r_4629 alcohol acyltransferase (hexanoyl-CoA) 5.85611122491521e-06 0.0001257434510284 2147.217602245408 5.617590284655946e-06 0.0001338209716946 2382.177498067286 4.197349390312803e-06 0.0001226205258362 2921.380005183175 7.0199953149483934e-06 0.0001896670763044 2701.812006918766 1.0093913062323037e-05 0.0003235356705867 3205.255172985773 2.091390751977822e-05 0.0004514278238781 2158.505403407804 2.207093883094728e-05 0.0005960108166706 2700.4325517632305 3.324455021461353e-05 0.0008976290840257 2700.078894829325 2.2122535399299344e-05 0.0007090482464807 3205.0948667627745 +r_4630 alcohol acyltransferase (octanoyl-CoA) 2.533704225540618e-06 8.953644141804328e-05 3533.8158462019705 4.086773766682387e-06 0.0001179439534396 2885.991742464209 3.2302001714375187e-06 0.0001142044029277 3535.520923366561 5.669192444699576e-06 0.0001795480170764 3167.0827693332403 1.4292787918584926e-05 0.0004124180362697 2885.497487397096 1.1734044753881836e-05 0.0003709042932355 3160.9244809879647 1.4103347221087306e-05 0.0004986950618974 3536.0049928561607 2.65892737158444e-05 0.0008413029634125 3164.0689866274606 3.1325070099854004e-05 0.0009038517847209 2885.394292302612 +r_4631 alcohol acyltransferase (butyryl-CoA) 1.1042055989926264e-05 0.0001788162422348 1619.4107546452817 3.1738202238560693e-06 0.0001122113668057 3535.530020330792 4.212380493690986e-06 0.0001302414616334 3091.873154112037 6.0044892499096e-06 0.0001898321988402 3161.504516693685 1.4486211171095252e-05 0.0004180241424415 2885.669258195017 4.616520148742415e-05 0.0006968789912189 1509.533087186498 1.823893653697969e-05 0.0005765640883571 3161.17163513409 3.8755034758480224e-05 0.0010351723225692 2671.0653958134467 3.538777500931679e-05 0.0009529046852012 2692.751055838708 +r_4632 alcohol acetyltransferase (hexanol) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4633 alcohol acyltransferase (decanoyl-CoA) 4.638310866311652e-06 0.0001238845635856 2670.8982462865133 5.401089317677116e-06 0.0001281551091722 2372.7641154318635 3.200976037807062e-06 0.0001131659373973 3535.3572179479684 8.886991250982595e-06 0.0002225607498251 2504.343073371448 1.399421988166714e-05 0.0003916379939795 2798.569675845869 9.403423114133514e-06 0.0003326362927995 3537.395784090694 1.7518200226738497e-05 0.0005539600301969 3162.1971608213607 4.3905513891491366e-05 0.0010645827461302 2424.713098134455 4.0946360385350845e-05 0.0010231362516693 2498.723310302855 +r_4634 ethyl hexanoate transport, mitochondrial 5.85611122491521e-06 0.0001257434510284 2147.217602245408 5.617590284655944e-06 0.0001338209716946 2382.1774980672867 4.197349390312803e-06 0.0001226205258362 2921.380005183175 7.0199953149483934e-06 0.0001896670763044 2701.812006918766 1.0093913062323037e-05 0.0003235356705867 3205.255172985773 2.091390751977822e-05 0.0004514278238781 2158.505403407804 2.207093883094728e-05 0.0005960108166706 2700.4325517632305 3.324455021461353e-05 0.0008976290840257 2700.0788948293243 2.2122535399299344e-05 0.0007090482464807 3205.0948667627745 +r_4635 ethyl octanoate transport, mitochondrial 2.5337042255406187e-06 8.953644141804328e-05 3533.81584620197 4.086773766682387e-06 0.0001179439534396 2885.991742464209 3.2302001714375187e-06 0.0001142044029277 3535.520923366561 5.669192444699576e-06 0.0001795480170764 3167.0827693332403 1.4292787918584928e-05 0.0004124180362697 2885.4974873970955 1.1734044753881836e-05 0.0003709042932355 3160.9244809879647 1.4103347221087306e-05 0.0004986950618974 3536.0049928561607 2.65892737158444e-05 0.0008413029634125 3164.0689866274606 3.1325070099854004e-05 0.0009038517847209 2885.394292302612 +r_4636 ethyl butanoate transport, mitochondrial 1.1042055989926264e-05 0.0001788162422348 1619.4107546452817 3.1738202238560693e-06 0.0001122113668057 3535.530020330792 4.212380493690986e-06 0.0001302414616334 3091.873154112037 6.0044892499096e-06 0.0001898321988402 3161.504516693685 1.4486211171095252e-05 0.0004180241424415 2885.669258195017 4.616520148742415e-05 0.0006968789912189 1509.533087186498 1.823893653697969e-05 0.0005765640883571 3161.1716351340906 3.8755034758480224e-05 0.0010351723225692 2671.0653958134467 3.538777500931679e-05 0.0009529046852012 2692.751055838708 +r_4637 hexyl acetate transport, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4638 ethyl decanoate transport, mitochondrial 4.638310866311652e-06 0.0001238845635856 2670.8982462865133 5.401089317677116e-06 0.0001281551091722 2372.7641154318635 3.200976037807062e-06 0.0001131659373973 3535.3572179479684 8.886991250982595e-06 0.0002225607498251 2504.343073371448 1.399421988166714e-05 0.0003916379939795 2798.569675845869 9.403423114133514e-06 0.0003326362927995 3537.395784090694 1.7518200226738497e-05 0.0005539600301969 3162.1971608213607 4.3905513891491366e-05 0.0010645827461302 2424.713098134455 4.0946360385350845e-05 0.0010231362516693 2498.723310302855 +r_4639 ethyl hexanoate transport 5.85611122491521e-06 0.0001257434510284 2147.217602245408 5.617590284655946e-06 0.0001338209716946 2382.177498067286 4.197349390312803e-06 0.0001226205258362 2921.380005183175 7.0199953149483934e-06 0.0001896670763044 2701.812006918766 1.0093913062323037e-05 0.0003235356705867 3205.255172985773 2.091390751977822e-05 0.0004514278238781 2158.505403407804 2.207093883094728e-05 0.0005960108166706 2700.4325517632305 3.324455021461353e-05 0.0008976290840257 2700.078894829325 2.2122535399299344e-05 0.0007090482464807 3205.0948667627745 +r_4640 ethyl octanoate transport 2.533704225540618e-06 8.953644141804328e-05 3533.8158462019705 4.086773766682388e-06 0.0001179439534396 2885.9917424642085 3.2302001714375187e-06 0.0001142044029277 3535.5209233665605 5.669192444699576e-06 0.0001795480170764 3167.0827693332403 1.4292787918584926e-05 0.0004124180362697 2885.497487397096 1.1734044753881836e-05 0.0003709042932355 3160.9244809879647 1.4103347221087306e-05 0.0004986950618974 3536.0049928561607 2.65892737158444e-05 0.0008413029634125 3164.0689866274606 3.1325070099854004e-05 0.0009038517847209 2885.394292302612 +r_4641 ethyl butanoate transport 1.1042055989926264e-05 0.0001788162422348 1619.4107546452817 3.1738202238560693e-06 0.0001122113668057 3535.530020330792 4.212380493690986e-06 0.0001302414616334 3091.873154112037 6.0044892499096e-06 0.0001898321988402 3161.504516693685 1.4486211171095252e-05 0.0004180241424415 2885.669258195017 4.616520148742415e-05 0.0006968789912189 1509.533087186498 1.823893653697969e-05 0.0005765640883571 3161.17163513409 3.8755034758480224e-05 0.0010351723225692 2671.0653958134467 3.538777500931679e-05 0.0009529046852012 2692.751055838708 +r_4642 hexyl acetate transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4643 ethyl decanoate transport 4.638310866311652e-06 0.0001238845635856 2670.8982462865133 5.401089317677116e-06 0.0001281551091722 2372.7641154318635 3.200976037807062e-06 0.0001131659373973 3535.3572179479684 8.886991250982595e-06 0.0002225607498251 2504.343073371447 1.399421988166714e-05 0.0003916379939795 2798.569675845869 9.403423114133514e-06 0.0003326362927995 3537.395784090694 1.7518200226738497e-05 0.0005539600301969 3162.1971608213607 4.3905513891491366e-05 0.0010645827461302 2424.713098134455 4.0946360385350845e-05 0.0010231362516693 2498.723310302855 +r_4644 ethyl hexanoate exchange 5.85611122491521e-06 0.0001257434510284 2147.217602245408 5.617590284655946e-06 0.0001338209716946 2382.177498067286 4.197349390312803e-06 0.0001226205258362 2921.380005183175 7.0199953149483934e-06 0.0001896670763044 2701.812006918766 1.0093913062323037e-05 0.0003235356705867 3205.255172985773 2.091390751977822e-05 0.0004514278238781 2158.505403407804 2.207093883094727e-05 0.0005960108166706 2700.4325517632315 3.324455021461353e-05 0.0008976290840257 2700.078894829325 2.2122535399299344e-05 0.0007090482464807 3205.0948667627745 +r_4645 ethyl octanoate exchange 2.533704225540618e-06 8.953644141804328e-05 3533.8158462019705 4.086773766682387e-06 0.0001179439534396 2885.991742464209 3.2302001714375187e-06 0.0001142044029277 3535.520923366561 5.669192444699576e-06 0.0001795480170764 3167.0827693332403 1.4292787918584928e-05 0.0004124180362697 2885.4974873970955 1.1734044753881836e-05 0.0003709042932355 3160.9244809879647 1.4103347221087306e-05 0.0004986950618974 3536.0049928561607 2.65892737158444e-05 0.0008413029634125 3164.0689866274606 3.1325070099854004e-05 0.0009038517847209 2885.394292302612 +r_4646 ethyl butanoate exchange 1.1042055989926264e-05 0.0001788162422348 1619.4107546452817 3.1738202238560693e-06 0.0001122113668057 3535.530020330792 4.212380493690986e-06 0.0001302414616334 3091.873154112037 6.0044892499096e-06 0.0001898321988402 3161.504516693685 1.4486211171095252e-05 0.0004180241424415 2885.669258195017 4.616520148742415e-05 0.0006968789912189 1509.533087186498 1.823893653697969e-05 0.0005765640883571 3161.17163513409 3.8755034758480224e-05 0.0010351723225692 2671.0653958134467 3.538777500931679e-05 0.0009529046852012 2692.751055838708 +r_4647 hexyl acetate exchange 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4648 ethyl decanoate exchange 4.638310866311652e-06 0.0001238845635856 2670.8982462865133 5.401089317677116e-06 0.0001281551091722 2372.7641154318635 3.200976037807063e-06 0.0001131659373973 3535.3572179479684 8.886991250982595e-06 0.0002225607498251 2504.343073371448 1.399421988166714e-05 0.0003916379939795 2798.569675845869 9.403423114133514e-06 0.0003326362927995 3537.395784090694 1.7518200226738497e-05 0.0005539600301969 3162.1971608213607 4.3905513891491366e-05 0.0010645827461302 2424.713098134455 4.0946360385350845e-05 0.0010231362516693 2498.723310302855 +r_4649 mitochondrial ethanol O-acetyltransferase 0.0004423819116839 0.005903885742197 1334.5676182200864 0.0002015668635323 0.0042468550810128 2106.921250144969 0.0004040454887865 0.0068987734893403 1707.424951101094 0.0005054823277448 0.0100306300985428 1984.368107050169 0.0014091795743213 0.0218786956595246 1552.5839331059365 0.0016278458944103 0.0211422334945875 1298.785933434208 0.0014296567358274 0.0252037621795753 1762.9240325991695 0.0024255918096797 0.0407314780652279 1679.2387697996855 0.0022188177882055 0.0380497452131933 1714.865700800302 +r_4650 ethyl acetate transport, mitochondrial 0.0004423819116839 0.005903885742197 1334.5676182200864 0.0002015668635323 0.0042468550810128 2106.9212501449697 0.0004040454887865 0.0068987734893403 1707.424951101094 0.0005054823277448 0.0100306300985428 1984.368107050169 0.0014091795743213 0.0218786956595246 1552.5839331059365 0.0016278458944103 0.0211422334945875 1298.785933434208 0.0014296567358274 0.0252037621795753 1762.9240325991695 0.0024255918096797 0.0407314780652279 1679.2387697996855 0.0022188177882055 0.0380497452131933 1714.865700800302 +r_4651 pyruvate decarboxylase (aldedyde-forming) 0.0002884294737827 0.0028098879353804 974.2027742617876 0.0002399965584746 0.002135092389725 889.6345861352623 0.0004740223088014 0.0036510781170267 770.2333939215388 0.0005228032836378 0.0044651825258177 854.0846367198978 0.0011584446037615 0.009562364032298 825.4485368785595 0.0014409189150363 0.0109899892730314 762.7069891545216 0.0020533809882683 0.0156600671132337 762.647906194952 0.0030403013428172 0.023237409595253 764.3127103223487 0.0026742051636964 0.0216508945635855 809.6198024559164 +r_4652 aldehyde dehydrogenase (1-propanol, NAD) 0.0001300090964791 0.0015918974613118 1224.4508303054745 2.290207670313788e-05 0.0006175623913952 2696.534464538832 0.0001320151574268 0.0018019708398015 1364.9726856549826 7.269511221731096e-05 0.0017269866898605 2375.657230843791 0.0003391135545604 0.0052347105806263 1543.6453395119356 0.0005537766236874 0.0061124453637505 1103.774536933282 0.0006028448836483 0.0083052365237791 1377.673884120488 0.0010642114806717 0.013881747602494 1304.416260735245 0.0009251531935463 0.0129560764900838 1400.4249869603016 +r_4653 aldehyde dehydrogenase (1-propanol, NAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4654 aldehyde dehydrogenase (1-propanol, NADP) 7.009799730221917e-06 0.000495641421071 7070.693031844283 7.248195859658979e-06 0.000362373542941 4999.499874968158 2.4895898852376608e-05 0.0008800255519724 3534.821366324986 2e-13 3.162530682865588e-11 15812.65341432794 5.539994400024289e-05 0.0022612513389849 4081.685243174626 5.704547078891835e-05 0.0023284116683743 4081.676662797641 0.000194717413613 0.0052009178145969 2671.008061422298 8.443922604090966e-05 0.0042215389803332 4999.499851275202 0.0001622322880307 0.0057340562139283 3534.4728743765027 +r_4655 1-propyl alcohol transport, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4656 propanal transport, cytosol 9.766113843243365e-05 0.002087238531058 2137.225271546541 9.055236335038912e-05 0.0011397537776236 1258.6681732572613 0.000201023777712 0.0025809013621643 1283.8786493513062 0.000311668251849 0.0034777090550222 1115.8368022377078 0.0004602922127433 0.0063893422093413 1388.1056495091932 0.0005286007066537 0.0076125946260611 1440.1408341377114 0.0009005847183595 0.010794297134862 1198.5876414297286 0.001328707706579 0.0162570201728126 1223.5211771796412 0.0010422898752873 0.0142368474718882 1365.920154214661 +r_4657 1-propyl alcohol transport, cytosol 0.0001037466495103 0.0013650047672711 1315.709734930424 1.863120596205284e-05 0.0005890825288051 3161.805682385782 0.000112562132375 0.0016939713863113 1504.921193804725 2.8755051481148115e-05 0.0011736695217301 4081.6116170045625 0.0002847480175137 0.0048930412013724 1718.375862313538 0.0005228064788629 0.0059993475776461 1147.5273968857312 0.0006323268939079 0.0087474266425228 1383.370963151866 0.0009335600996504 0.013123461082845 1405.743571062894 0.0009493852992566 0.0133007258404856 1400.9829150399253 +r_4658 propanal exchange 9.766113843243365e-05 0.002087238531058 2137.225271546541 9.055236335038912e-05 0.0011397537776236 1258.6681732572613 0.000201023777712 0.0025809013621643 1283.8786493513062 0.000311668251849 0.0034777090550222 1115.8368022377078 0.0004602922127433 0.0063893422093413 1388.1056495091932 0.0005286007066537 0.0076125946260611 1440.1408341377114 0.0009005847183595 0.010794297134862 1198.5876414297286 0.001328707706579 0.0162570201728126 1223.5211771796412 0.0010422898752873 0.0142368474718882 1365.920154214661 +r_4659 propanol exchange 0.0001037466495103 0.0013650047672711 1315.709734930424 1.863120596205284e-05 0.0005890825288051 3161.805682385782 0.000112562132375 0.0016939713863113 1504.921193804725 2.8755051481148115e-05 0.0011736695217301 4081.6116170045625 0.0002847480175137 0.0048930412013724 1718.375862313538 0.0005228064788629 0.0059993475776461 1147.5273968857312 0.0006323268939079 0.0087474266425228 1383.370963151866 0.0009335600996504 0.013123461082845 1405.743571062894 0.0009493852992566 0.0133007258404856 1400.9829150399253 +r_4660 2-oxo acid decarboxylase 1.9299140933300284e-05 0.000312646743973 1620.003424264483 1.692852501634446e-05 0.0002912956536514 1720.738536701613 1.3025978031608812e-05 0.0002771915225944 2127.9900973407043 3.265215864692784e-05 0.0005291342641208 1620.518477330883 5.585221242448881e-05 0.0009824008274427 1758.9291181096155 6.39628967807945e-05 0.0010643819022968 1664.0614416581916 7.350419045726422e-05 0.0013870839533284 1887.08146392672 0.0001246031541415 0.0021988639416517 1764.6936442340852 0.0001293258668649 0.0022150924698817 1712.7992439397349 +r_4661 aldehyde dehydrogenase (methionol, NAD) 1.110349588186912e-05 0.0002366283227892 2131.115509086473 9.414335928684916e-06 0.0002113819260257 2245.3195597332137 5.852502751611589e-06 0.0001848296945973 3158.1308449009102 1.4989914279817627e-05 0.0003531130113892 2355.670651597383 3.067822604604448e-05 0.0007227221733347 2355.8147470782337 3.836943789287076e-05 0.0008172641263923 2129.987227527903 3.079061172411809e-05 0.000888038304278 2884.120368360333 7.036854627570382e-05 0.0016577658169161 2355.833543044914 7.505490110705378e-05 0.0016772206982985 2234.658461419084 +r_4662 aldehyde dehydrogenase (methionol, NAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4663 aldehyde dehydrogenase (methionol, NADP) 9.945110799279875e-07 7.032041158017765e-05 7070.85250224357 9.946300855851278e-07 7.033096782893893e-05 7071.067811865368 4.695409800747953e-06 0.0001659579857482 3534.47287437605 1.5770537793255769e-06 0.0001115145421656 7071.0678118651895 1.0608372683556156e-05 0.0004240720241556 3997.5219273074 1.0699657933783767e-05 0.0004363935669135 4078.574937761624 2.080582217581636e-05 0.0007353761410955 3534.472874378061 2.4073856943220897e-05 0.0009621969421832 3996.8541162832 3.033314947215958e-05 0.0010721169329633 3534.472851054921 +r_4664 methionol transport, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4665 methional transport, cytosol 7.201133971503035e-06 0.0001923706371704 2671.3936712151044 6.519559002074416e-06 0.0001880927800668 2885.0537284345805 2.4780654792490386e-06 0.0001234436847061 4981.453708136808 1.6085190587784642e-05 0.0003787336432427 2354.54868362215 1.4565613694890531e-05 0.0005145882442634 3532.8977895656044 1.489380095414292e-05 0.0005261483836319 3532.666948161468 2.190775655733449e-05 0.0007734045106228 3530.277089754833 3.0160750922664225e-05 0.0010817019723868 3586.4557058292585 2.393781628576332e-05 0.0009765918061202 4079.702987365103 +r_4666 methionol transport, cytosol 7.283660186434007e-06 0.000194512691459 2670.534957428316 3.735993994199936e-06 0.0001337625707723 3580.37435231418 9.40382831908404e-06 0.0002349489786552 2498.43968523361 6.719616689904738e-06 0.0002376591120322 3536.7956685581 2.4518422063641467e-05 0.0006491454303949 2647.5824125628924 2.50537680913784e-05 0.0006687905100153 2669.420853486436 3.645713627012283e-05 0.0009737991329758 2671.0796091077573 5.6199124848184845e-05 0.0014877981653217 2647.36892138595 6.864589917272151e-05 0.0016168150462414 2355.29735312136 +r_4667 methional exchange 7.201133971503035e-06 0.0001923706371704 2671.3936712151044 6.519559002074416e-06 0.0001880927800668 2885.0537284345805 2.4780654792490386e-06 0.0001234436847061 4981.453708136808 1.6085190587784642e-05 0.0003787336432427 2354.54868362215 1.4565613694890531e-05 0.0005145882442634 3532.8977895656044 1.489380095414292e-05 0.0005261483836319 3532.666948161468 2.190775655733449e-05 0.0007734045106228 3530.277089754833 3.0160750922664225e-05 0.0010817019723868 3586.4557058292585 2.393781628576332e-05 0.0009765918061202 4079.702987365103 +r_4668 methionol exchange 7.283660186434007e-06 0.000194512691459 2670.534957428316 3.735993994199936e-06 0.0001337625707723 3580.37435231418 9.40382831908404e-06 0.0002349489786552 2498.43968523361 6.719616689904738e-06 0.0002376591120322 3536.7956685581 2.4518422063641467e-05 0.0006491454303949 2647.5824125628924 2.50537680913784e-05 0.0006687905100153 2669.420853486436 3.645713627012284e-05 0.0009737991329758 2671.079609107757 5.6199124848184845e-05 0.0014877981653217 2647.36892138595 6.864589917272151e-05 0.0016168150462414 2355.29735312136 +r_4669 pyruvate decarboxylase (hydroxy-phenyl) 5.525533325643409e-05 0.0008748154541457 1583.2235597707916 3.155362496965165e-05 0.0005771175167135 1829.005438419796 0.0001786611181135 0.001883492738399 1054.226436219618 0.0002185958086334 0.0024670995737176 1128.612478501231 0.000426702553746 0.0049612287537942 1162.6901949001983 0.0003736441907514 0.004341353467674 1161.8950796325043 0.0007132806305737 0.0078315311478367 1097.9593181350883 0.0009745426046147 0.0113373439069491 1163.3502581891617 0.0009227170241834 0.010763532631487 1166.5041772705551 +r_4670 aldehyde dehydrogenase (tyrosol, NAD) 4.6930765415232565e-05 0.0008066003736275 1718.702788013124 1.7784337098980868e-05 0.0004198833849589 2360.9729315295444 3.0951537890685005e-05 0.0007307921351589 2361.085054125328 5.048019549911445e-05 0.0011303962314622 2239.2865564121057 9.290428320883344e-05 0.0021945483199318 2362.1605421558784 0.0002880923092682 0.0037500953653055 1301.6992278729142 0.0001361463386536 0.003214681434154 2361.195656044056 0.0001655650397223 0.004432551500027 2677.226730630729 0.0002026079999463 0.0047895052928329 2363.927038468768 +r_4671 aldehyde dehydrogenase (tyrosol, NAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4672 aldehyde dehydrogenase (tyrosol, NADP) 2.723956109198533e-06 0.0001926125483724 7071.059174631429 4.169824127759516e-11 2.94851091709434e-09 7071.067811866209 3.585494766242768e-06 0.0002535327663119 7071.067811865423 5.031823016192441e-06 0.000355803617648 7071.067811866154 2.096290975119561e-05 0.0010480406468004 4999.499874966926 1.0487132966724496e-05 0.0007415522821824 7071.067798371458 1.5809459053544405e-05 0.0011178975986551 7071.067990808567 2.381205592832039e-05 0.0016837664636536 7071.067146499735 2.310631141857869e-05 0.0016236032801063 7026.66579141186 +r_4673 tyrosol transport, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4674 (4-hydroxyphenyl)acetaldehyde transport, cytosol 5.600611732002514e-06 0.0002800186023895 4999.786019613813 1.3769246172429344e-05 0.0003965506991346 2879.9739228185367 0.0001441240854566 0.0017202872383372 1193.6153717030968 0.0001630837901181 0.0021681343418868 1329.4603591910154 0.000312835360786 0.0043329566045695 1385.0597303586444 7.506474851653333e-05 0.0019564672484003 2606.372880832925 0.0005613248328664 0.0070656876128616 1258.7520093810203 0.0007851655089641 0.0103130070946904 1313.4819317645058 0.0006970027128185 0.0095170844307226 1365.4300414753538 +r_4675 tyrosol transport, cytosol 4.033727963795028e-05 0.0007614109409698 1887.6110332771848 1.2446361196301364e-05 0.0003591145371334 2885.297409175167 1.4939579074738388e-05 0.000528175885443 3535.41343300759 4.194820251762529e-05 0.0010481012389935 2498.560548698508 7.606574992115619e-05 0.0020322376004388 2671.685485971448 0.0002472402410958 0.0035243429767155 1425.4730383270864 6.573408092590913e-05 0.0023239121316871 3535.3230758737054 0.0001240106537892 0.0039207747982876 3161.643518910415 0.0001437385042486 0.0041480172027207 2885.807963846986 +r_4676 (4-hydroxyphenyl)acetaldehyde exchange 5.600611732002514e-06 0.0002800186023895 4999.786019613813 1.3769246172429344e-05 0.0003965506991346 2879.9739228185363 0.0001441240854566 0.0017202872383372 1193.6153717030968 0.0001630837901181 0.0021681343418868 1329.4603591910154 0.000312835360786 0.0043329566045695 1385.0597303586444 7.506474851653334e-05 0.0019564672484003 2606.372880832925 0.0005613248328664 0.0070656876128616 1258.7520093810203 0.0007851655089641 0.0103130070946904 1313.4819317645058 0.0006970027128185 0.0095170844307226 1365.4300414753538 +r_4677 tyrosol exchange 4.033727963795028e-05 0.0007614109409698 1887.6110332771848 1.2446361196301364e-05 0.0003591145371334 2885.297409175167 1.4939579074738388e-05 0.000528175885443 3535.41343300759 4.194820251762529e-05 0.0010481012389935 2498.560548698508 7.60657499211562e-05 0.0020322376004388 2671.685485971447 0.0002472402410958 0.0035243429767155 1425.4730383270864 6.573408092590913e-05 0.0023239121316871 3535.3230758737054 0.0001240106537892 0.0039207747982876 3161.643518910415 0.0001437385042486 0.0041480172027207 2885.807963846986 +r_4678 aldehyde dehydrogenase 5.374943914094382e-05 0.0011549041865792 2148.681372378323 0.0001192939225614 0.0015160637393664 1270.8641872221033 0.0001160874748101 0.0018144543633557 1563.006143706018 0.0001384399193714 0.0025254228509955 1824.2013304117256 0.0003036388924574 0.0049574280831236 1632.6722980056895 0.0003014961139062 0.0050094941594316 1661.5451836270736 0.0003552339726474 0.0071027273684253 1999.4504792122984 0.0005629429295254 0.0103985062722311 1847.1688206469728 0.000544529806832 0.0102340288192089 1879.424907655201 +r_4679 short-chain-fatty-acid-CoA ligase (propionate) 5.374940584157767e-05 0.0011549041881301 2148.682706436221 0.0001192939225614 0.0015160637393664 1270.8641872221033 0.0001160869178772 0.0018144543990038 1563.013673015035 0.0001384393853731 0.0025254228802792 1824.2083880044795 0.0003036385541914 0.0049574281038481 1632.6741236960129 0.0003014960009241 0.0050094941662333 1661.5458085276196 0.000355233559924 0.0071027273890731 1999.4528080602872 0.0005629426751271 0.0103985062860074 1847.1696578446408 0.0005445289321519 0.0102340288657606 1879.4279351360144 +r_4680 alcohol acyltransferase (propionyl-CoA) 6.102549869445207e-05 0.0009379193648466 1536.9302749047 2.4353419382465925e-05 0.0005440514344098 2233.983761646178 4.607886396841171e-05 0.0009828184724184 2132.9051712130063 7.12944342711562e-05 0.0014556966767781 2041.8097031834056 0.0001304533875456 0.0026788870480527 2053.520493758481 0.0002214757390115 0.0032983498106587 1489.260099268232 0.0001439319932442 0.0034142429699716 2372.1223426525607 0.0002721985698368 0.0055903093595344 2053.7614737969006 0.0002585244397412 0.0053583721645942 2072.6752836044216 +r_4681 propionyl-CoA transport, mitochondrial 5.374940584157767e-05 0.0011549041881301 2148.682706436221 0.0001192939225614 0.0015160637393664 1270.864187222106 0.0001160869178772 0.0018144543990038 1563.013673015035 0.0001384393853731 0.0025254228802792 1824.2083880044795 0.0003036385541914 0.0049574281038481 1632.6741236960129 0.0003014960033461 0.0050094941660875 1661.5457951313322 0.000355233559924 0.0071027273890731 1999.4528080602872 0.0005629426782983 0.0103985062858356 1847.1696474083933 0.0005445289449308 0.0102340288650805 1879.4278909049424 +r_4682 butyryl-CoA transport, mitochondrial 1.1042145428478837e-05 0.0001788162367218 1619.3975879057275 3.1738200239320766e-06 0.0001122113668114 3535.5302432175754 4.212421836660306e-06 0.0001302414603042 3091.842777253781 6.0044894499096e-06 0.0001898321988339 3161.5044112837386 1.448621641779994e-05 0.0004180241422596 2885.6682117906803 4.616519038092041e-05 0.0006968789919563 1509.5334519498892 1.823893965853751e-05 0.0005765640882584 3161.1710935651004 3.875512680189386e-05 0.0010351723191236 2671.059043143336 3.538787542234527e-05 0.0009529046814736 2692.743404629483 +r_4683 hexanoyl-CoA transport, mitochondrial 5.856217043880855e-06 0.0001257434461172 2147.178719214884 5.617590284655946e-06 0.0001338209716946 2382.177498067286 4.197349590312803e-06 0.0001226205258294 2921.379865818891 7.0199953149483934e-06 0.0001896670763044 2701.812006918766 1.0093913062323037e-05 0.0003235356705867 3205.255172985773 2.091399140601794e-05 0.0004514278199953 2158.496727054345 2.2070939697613936e-05 0.0005960108166385 2700.4324455789506 3.3244558572524845e-05 0.000897629083716 2700.078215079536 2.212253658929935e-05 0.0007090482464436 3205.0946941889324 +r_4684 octanoyl-CoA transport, mitochondrial 2.5337717016542e-06 8.953643952230269e-05 3533.7216633940566 4.086773766682387e-06 0.0001179439534396 2885.991742464209 3.2302001714375187e-06 0.0001142044029277 3535.520923366561 5.669191845196251e-06 0.0001795480170953 3167.083104578575 1.4292787918584926e-05 0.0004124180362697 2885.497487397096 1.1734063697612157e-05 0.0003709042926362 3160.919372815031 1.4103347906801592e-05 0.0004986950618781 3536.004820795942 2.658928584059992e-05 0.0008413029630297 3164.067542367502 3.1325072586662466e-05 0.0009038517846346 2885.394062963806 +r_4685 decanoyl-CoA transport, mitochondrial 4.638331857001686e-06 0.000123884562809 2670.8861424402658 5.401089117677116e-06 0.0001281551091806 2372.7642034503374 3.200975944927706e-06 0.0001131659374 3535.357320612144 8.886991050982595e-06 0.0002225607498331 2504.3431298211194 1.3994220548333807e-05 0.0003916379939556 2798.5695423552947 9.403425136145658e-06 0.0003326362927431 3537.395022846893 1.7518200726738495e-05 0.0005539600301811 3162.1970704766345 4.390551570815804e-05 0.0010645827460552 2424.7129976369965 4.0946383641066856e-05 0.0010231362507387 2498.7218888670004 +r_4686 propionate transport, cytosol -5.374943914094382e-05 0.0011549041865792 -2148.681372378323 -0.0001192939225614 0.0015160637393664 -1270.8641872221033 -0.0001160874748101 0.0018144543633557 -1563.0061437060183 -0.0001384399193714 0.0025254228509955 -1824.2013304117256 -0.0003036388924574 0.0049574280831236 -1632.6722980056895 -0.0003014961139062 0.0050094941594316 -1661.5451836270736 -0.0003552339726474 0.0071027273684253 -1999.4504792122984 -0.0005629429295254 0.0103985062722311 -1847.1688206469728 -0.000544529806832 0.0102340288192089 -1879.424907655201 +r_4687 alcohol acetyltransferase (tyrosol) 9.317441886480809e-06 0.0003293224331601 3534.4726285656416 5.338017600920783e-06 0.0002178800581937 4081.6661630375 1.959745358218938e-05 0.0005654466761518 2885.3068781638367 1.356381599768162e-05 0.0005536296063104 4081.665560820661 3.780144303887288e-05 0.0013365245870182 3535.64435528 5.1339201139130976e-05 0.0014871009713575 2896.61883777175 8.62217167813304e-05 0.0024880386568415 2885.6287600391465 6.536644186141215e-05 0.0026680398005722 4081.665950594264 8.197580711634461e-05 0.0029001677976492 3537.833782512402 +r_4688 tyrosyl acetate transport 9.317441886480809e-06 0.0003293224331601 3534.4726285656416 5.338017600920782e-06 0.0002178800581937 4081.6661630375 1.9597453582189385e-05 0.0005654466761518 2885.306878163836 1.356381599768162e-05 0.0005536296063104 4081.665560820661 3.780144303887288e-05 0.0013365245870182 3535.64435528 5.1339201139130976e-05 0.0014871009713575 2896.61883777175 8.62217167813304e-05 0.0024880386568415 2885.6287600391465 6.536644186141215e-05 0.0026680398005722 4081.665950594264 8.197580711634461e-05 0.0029001677976492 3537.833782512402 +r_4689 tyrosyl acetate exchange 9.317441886480809e-06 0.0003293224331601 3534.4726285656416 5.338017600920783e-06 0.0002178800581937 4081.6661630375 1.9597453582189385e-05 0.0005654466761518 2885.3068781638367 1.356381599768162e-05 0.0005536296063104 4081.665560820661 3.780144303887288e-05 0.0013365245870182 3535.6443552799988 5.1339201139130976e-05 0.0014871009713575 2896.618837771749 8.622171678133042e-05 0.0024880386568415 2885.628760039146 6.536644186141215e-05 0.0026680398005722 4081.665950594264 8.197580711634461e-05 0.0029001677976492 3537.833782512402 +r_4690 alcohol acetyltransferase (methionol) 4.814346775363105e-06 0.0001521538487253 3160.425615869928 6.672972020070107e-06 0.0001782343702156 2670.989323491277 1.1440842332755028e-06 8.043382252240378e-05 7030.410889600539 9.847351369238464e-06 0.0002841259102544 2885.3028555682995 1.676817666595916e-05 0.0005300434502645 3161.0082647838703 2.401532773527612e-05 0.0006414527612666 2671.0139804772984 1.5139297629811622e-05 0.0006171936204013 4076.765220508245 3.8243278370739904e-05 0.0012088745653634 3161.011861076162 3.67421514064918e-05 0.0011614234069909 3161.010889486826 +r_4691 methionyl acetate transport 4.814346775363104e-06 0.0001521538487253 3160.4256158699286 6.672972020070107e-06 0.0001782343702156 2670.989323491277 1.144084233275503e-06 8.043382252240379e-05 7030.410889600539 9.847351369238464e-06 0.0002841259102544 2885.3028555682995 1.6768176665959157e-05 0.0005300434502645 3161.008264783872 2.401532773527612e-05 0.0006414527612666 2671.0139804772984 1.5139297629811622e-05 0.0006171936204013 4076.765220508245 3.824327837073989e-05 0.0012088745653634 3161.011861076163 3.67421514064918e-05 0.0011614234069909 3161.010889486826 +r_4692 methionyl acetate exchange 4.814346775363104e-06 0.0001521538487253 3160.4256158699286 6.672972020070107e-06 0.0001782343702156 2670.989323491277 1.144084233275503e-06 8.043382252240379e-05 7030.410889600539 9.847351369238464e-06 0.0002841259102544 2885.3028555682995 1.6768176665959157e-05 0.0005300434502645 3161.008264783872 2.401532773527612e-05 0.0006414527612666 2671.0139804772984 1.5139297629811622e-05 0.0006171936204013 4076.765220508245 3.8243278370739904e-05 0.0012088745653634 3161.011861076162 3.67421514064918e-05 0.0011614234069909 3161.010889486826 +r_4693 alcohol acetyltransferase (propanol) 3.327224669909178e-05 0.0009600232265131 2885.3573826721035 1.1519066600743505e-05 0.0004071571433344 3534.63659380297 4.4348923904178e-05 0.0010749029294299 2423.7407242449176 4.394006093616287e-05 0.0012678763628676 2885.467921197652 0.0001097654810469 0.002932327174484 2671.447477398245 8.801561561336609e-05 0.0026115461289617 2967.139536276936 0.0001652354033533 0.0044139799354731 2671.32820563486 0.0002150906070622 0.0062065287640709 2885.541516127702 0.0001380001823204 0.0048776894829873 3534.5529266470826 +r_4694 propyl acetate transport 3.327224669909178e-05 0.0009600232265131 2885.357382672103 1.1519066600743505e-05 0.0004071571433344 3534.63659380297 4.4348923904178e-05 0.0010749029294299 2423.7407242449176 4.394006093616287e-05 0.0012678763628676 2885.467921197651 0.0001097654810469 0.002932327174484 2671.4474773982456 8.801561561336609e-05 0.0026115461289617 2967.139536276936 0.0001652354033533 0.0044139799354731 2671.32820563486 0.0002150906070622 0.0062065287640709 2885.5415161277024 0.0001380001823204 0.0048776894829873 3534.5529266470826 +r_4695 propyl acetate exchange 3.327224669909178e-05 0.0009600232265131 2885.357382672103 1.1519066600743505e-05 0.0004071571433344 3534.63659380297 4.4348923904178e-05 0.0010749029294299 2423.7407242449176 4.394006093616287e-05 0.0012678763628676 2885.467921197652 0.0001097654810469 0.002932327174484 2671.4474773982456 8.801561561336609e-05 0.0026115461289617 2967.139536276936 0.0001652354033533 0.0044139799354731 2671.32820563486 0.0002150906070622 0.0062065287640709 2885.5415161277024 0.0001380001823204 0.0048776894829873 3534.5529266470826 +r_4697 ethyl propionate transport, mitochondrial 6.102549869445207e-05 0.0009379193648466 1536.9302749047 2.435341938246592e-05 0.0005440514344098 2233.983761646178 4.607886396841171e-05 0.0009828184724184 2132.9051712130063 7.12944342711562e-05 0.0014556966767781 2041.8097031834056 0.0001304533875456 0.0026788870480527 2053.5204937584804 0.0002214757390115 0.0032983498106587 1489.260099268232 0.0001439319932442 0.0034142429699716 2372.1223426525607 0.0002721985698368 0.0055903093595344 2053.7614737969006 0.0002585244397412 0.0053583721645942 2072.6752836044216 +r_4698 ethyl propionate transport 6.102549869445207e-05 0.0009379193648466 1536.9302749047 2.4353419382465925e-05 0.0005440514344098 2233.9837616461773 4.607886396841171e-05 0.0009828184724184 2132.9051712130063 7.12944342711562e-05 0.0014556966767781 2041.8097031834056 0.0001304533875456 0.0026788870480527 2053.520493758481 0.0002214757390115 0.0032983498106587 1489.260099268232 0.0001439319932442 0.0034142429699716 2372.1223426525607 0.0002721985698368 0.0055903093595344 2053.7614737969006 0.0002585244397412 0.0053583721645942 2072.6752836044216 +r_4699 ethyl propionate exchange 6.102549869445207e-05 0.0009379193648466 1536.9302749047 2.4353419382465925e-05 0.0005440514344098 2233.9837616461773 4.607886396841171e-05 0.0009828184724184 2132.9051712130063 7.12944342711562e-05 0.0014556966767781 2041.8097031834056 0.0001304533875456 0.0026788870480527 2053.520493758481 0.0002214757390115 0.0032983498106587 1489.260099268232 0.0001439319932442 0.0034142429699716 2372.1223426525607 0.0002721985698368 0.0055903093595344 2053.7614737969006 0.0002585244397412 0.0053583721645942 2072.6752836044216 +r_4700 hydrogen sulfide transport 0.0001200318246404 0.0013941842145221 1161.5121395500666 1.989188412483697e-05 0.0005748625223849 2889.93500453376 1.6590693417254557e-05 0.0005862568115502 3533.6486354485123 2.9492408967803e-05 0.0009321560371312 3160.6642853381745 3.669128958830775e-05 0.00149756335482 4081.52281269856 0.0001471113165433 0.0026330627776808 1789.8437996133755 9.191597933344433e-05 0.0029054618131599 3160.9975047100584 8.35897835654958e-05 0.0034119674181364 4081.799560424807 8.040688433119534e-05 0.0032820099802178 4081.752461268495 +r_4701 L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming) 2.1968844284760136e-05 0.0007141577469088 3250.775223548076 6.207607682592062e-05 0.0016585685633404 2671.8321262336594 3.437741528948472e-05 0.0010949749132232 3185.157767105845 5.589021661232353e-05 0.0017667096763884 3161.0356578916835 0.0001499997668857 0.0040152678697656 2676.849406589519 0.0001741381052839 0.0039241173401413 2253.451267166732 0.0001910083770435 0.0055265523240979 2893.355992883235 0.0002991870797237 0.0086423561042466 2888.612740973368 0.0001889356030241 0.0066907582614484 3541.290341446724 +r_4702 L-cysteine:2-oxoglutarate aminotransferase 3.15436234466255e-06 0.0002229086063537 7066.677255100179 7.764235064904589e-06 0.0003880526518151 4997.950842178708 9.69114591909643e-06 0.0004844440830756 4998.83179058415 2.231923145595731e-05 0.0009109055868771 4081.258750663545 1.295199984443597e-05 0.000915703480318 7069.977542590676 2.6071497389347125e-05 0.0013033474169603 4999.127581728164 3.938419274063063e-05 0.0019689206918856 4999.266342342465 5.790350763830914e-05 0.0028947852073564 4999.326164208504 2.830582729924213e-05 0.0020013684853113 7070.517544509175 +r_4703 3-mercaptopyruvate sulfurtransferase 3.154362344662561e-06 0.0002229086063537 7066.677255100153 7.764235064904589e-06 0.0003880526518151 4997.950842178708 9.69114591909643e-06 0.0004844440830756 4998.83179058415 2.231923145595731e-05 0.0009109055868771 4081.258750663545 1.295199984443597e-05 0.000915703480318 7069.977542590676 2.6071497389347125e-05 0.0013033474169603 4999.127581728163 3.938419274063063e-05 0.0019689206918856 4999.266342342465 5.790350763830914e-05 0.0028947852073564 4999.326164208504 2.830582729924213e-05 0.0020013684853113 7070.517544509175 +r_4705 taurocholate transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4707 trithionate thiosulfohydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4708 hydrogen sulfide exchange 0.0001200318246404 0.0013941842145221 1161.5121395500666 1.989188412483697e-05 0.0005748625223849 2889.93500453376 1.6590693417254557e-05 0.0005862568115502 3533.6486354485123 2.9492408967803e-05 0.0009321560371312 3160.6642853381745 3.669128958830775e-05 0.00149756335482 4081.52281269856 0.0001471113165433 0.0026330627776808 1789.8437996133755 9.191597933344433e-05 0.0029054618131599 3160.9975047100584 8.358978356549583e-05 0.0034119674181364 4081.7995604248063 8.040688433119536e-05 0.0032820099802178 4081.7524612684942 +r_4710 taurocholate exchange 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4711 ethyl-(2S)-lactate esterase, c 6.862221431584008e-05 0.0015330775987265 2234.083545702051 3.2913863632343884e-05 0.0007751847021741 2355.1920577699234 5.3733138891004575e-05 0.0014352577855618 2671.084949035224 8.272419416868286e-05 0.0019494732309412 2356.593800075022 0.0002040666617215 0.0048060704398551 2355.1472833976445 0.0001398739241495 0.0040358512732324 2885.3492870608006 0.0002045855251014 0.0059029427806496 2885.317901997972 0.0004136636650795 0.0103343978048314 2498.2609489874467 0.0004472667089893 0.0105337669020456 2355.1421758727765 +r_4712 ethyl-(2R)-lactate esterase, c 2.006811394565132e-05 0.0008558196931394 4264.574615517933 7.756093041041221e-07 5.4896054769533416e-05 7077.797349651683 1.7339877408929628e-05 0.0008669515226913 4999.75577823209 9.74543270249004e-06 0.0006891701609177 7071.724590963333 3.6021415855713938e-06 0.0002547488435731 7072.149651018087 6.947384664730294e-05 0.0028884482979345 4157.6052533815855 3.843660335464124e-05 0.0027179352637024 7071.216045353933 5.781513966776614e-05 0.004088207945193 7071.171960641995 7.1722395926758e-06 0.0005072188789283 7071.973438342975 +r_4713 diethyl-succinate esterase, c -9.799999999999654e-10 1.4001400210035194e-10 -14.287143071464987 -9.993999999999583e-10 2.4489996978164182e-11 -2.450469979804403 -9.959999999999598e-10 6.312524819271919e-11 -6.337876324570456 -9.49799999999976e-10 2.1929336040013135e-10 -23.08837233103148 -9.929999999999611e-10 8.338099590491861e-11 -8.396877734634632 -9.733999999999675e-10 1.6092737344499402e-10 -16.532501894904392 -9.929999999999611e-10 8.338099590491689e-11 -8.396877734634462 -9.89599999999962e-10 1.0145885264360168e-10 -10.252511382741064 -9.951999999999601e-10 6.912246800510111e-11 -6.945585611445326 +r_4714 monoethyl-succinate esterase, c -9.903999999999618e-10 9.751790578345163e-11 -9.846315204306888 -9.993999999999583e-10 2.4489996978164182e-11 -2.450469979804403 -9.99799999999958e-10 1.414213562372846e-11 -1.4144964616652378 -9.99799999999958e-10 1.4142135623729846e-11 -1.4144964616653766 -9.951999999999601e-10 6.912246800509976e-11 -6.945585611445189 -9.911999999999614e-10 9.340398739332948e-11 -9.423323990449266 -9.98399999999959e-10 3.997198458809068e-11 -4.003604225570144 -9.965999999999595e-10 5.821613026957997e-11 -5.841474038689778 -9.995999999999586e-10 1.999799949987206e-11 -2.000600190063314 +r_4715 ethyl-benzoate esterase, c 9.335999999999816e-10 3.5385884645807135e-10 37.90261851521834 -9.017999999999923e-10 3.1396890816616277e-10 -34.81580263541421 -9.421999999999786e-10 3.3238720831470435e-10 -35.27777630171003 -9.711999999999683e-10 2.2886903724016782e-10 -23.56559279655841 -9.503999999999755e-10 2.9522410378270103e-10 -31.06314223302909 8.807999999999997e-10 4.6025398069472685e-10 52.25408500167199 -9.423999999999783e-10 3.2604217625966353e-10 -34.59700512093283 -6.814000000000348e-10 7.29383602837342e-10 -107.04191412346708 -9.52199999999975e-10 3.025449829254162e-10 -31.773260126593584 +r_4716 ethyl-pyruvate esterase, c 0.0464013688063878 0.0165998900738629 35.774569804453144 0.0001301309937858 0.0021089579730801 1620.642332564153 0.2022466216008976 0.0362558835392811 17.92657066520822 0.0004432882132089 0.0051601377628536 1164.059320571547 0.1945696218974703 0.0865094032091792 44.46192697787424 0.4947393430786017 0.0602538952741418 12.178917265645689 0.2090348043274515 0.1004017919240181 48.03113636843912 0.689580606434669 0.232649343031546 33.73780249337498 0.7418552287917177 0.2181854710940872 29.41078833527298 +r_4717 benzyl-acetate esterase, c 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4718 isobutyraldehyde dehydrogenase, c 4.842286502114825e-05 0.0013972090752241 2885.4324803251025 1.7319807691746057e-05 0.0004997576772014 2885.468973420827 7.422380481524617e-05 0.0016611480251776 2238.0259666187467 4.406892528951229e-05 0.0012715477449914 2885.361366627268 0.0001562712212602 0.0041740433817522 2671.0249962153584 0.0001838883962378 0.0045940063501943 2498.2578804224613 0.0002954027569026 0.0069571595341334 2355.143739036584 0.0003565119278462 0.0095224858043352 2671.0146451096343 0.0003424800820564 0.0091476968305475 2671.0157202777905 +r_4719 2-methylbutanal dehydrogenase, c 4.034221282381097e-05 0.0010775525317145 2671.0298129174066 1.2865520209608403e-05 0.0003730369779616 2899.509478699621 1.5381957562385894e-05 0.0006278806633049 4081.929499274548 3.987558636445398e-05 0.0010651031832355 2671.065883522747 6.04915423027279e-05 0.0021380899341373 3534.527064027202 4.966527444195708e-05 0.0019180201313099 3861.893753454413 6.790794954765106e-05 0.0027718158048747 4081.725075397479 0.0001380041384326 0.0048777471253833 3534.493371561777 0.0001325723424966 0.0046857666597314 3534.4978986482333 +r_4720 ethyl-isobutyrate esterase, c 4.842286502114825e-05 0.0013972090752241 2885.4324803251025 1.7319807691746057e-05 0.0004997576772014 2885.468973420827 7.422380481524617e-05 0.0016611480251776 2238.025966618747 4.406892528951229e-05 0.0012715477449914 2885.361366627268 0.0001562712212602 0.0041740433817522 2671.0249962153584 0.0001838883962378 0.0045940063501943 2498.2578804224613 0.0002954027569026 0.0069571595341334 2355.143739036584 0.0003565119278462 0.0095224858043352 2671.014645109635 0.0003424800820564 0.0091476968305475 2671.0157202777905 +r_4721 ethyl-2-methylbutyrate esterase, c 4.034221282381097e-05 0.0010775525317145 2671.0298129174066 1.2865520209608403e-05 0.0003730369779616 2899.509478699621 1.5381957562385894e-05 0.0006278806633049 4081.929499274548 3.987558636445398e-05 0.0010651031832355 2671.065883522747 6.04915423027279e-05 0.0021380899341373 3534.527064027202 4.966527444195708e-05 0.0019180201313099 3861.893753454413 6.790794954765106e-05 0.0027718158048747 4081.725075397479 0.0001380041384326 0.0048777471253833 3534.493371561777 0.0001325723424966 0.0046857666597314 3534.4978986482333 +r_4722 polyphosphate polymerase, c 4.181953992861473e-05 0.0011047172870967 2641.629460731724 3.2252790638407665e-05 0.0013164294584793 4081.598622699444 3.63333918684489e-05 0.0012841899362389 3534.4620201949624 4.025488362635099e-05 0.0016430669599235 4081.6587005309134 5.35792241968008e-05 0.0026786913425074 4999.496320940341 6.565769065178075e-05 0.0026799180889692 4081.651459815059 0.0001610603963024 0.005692635274944 3534.4724126056994 0.0005649651200195 0.0141908490735084 2511.8097685425314 0.0003370981351103 0.0107149139791252 3178.5740895949925 +r_4723 polyphosphate phosphohydrolase, v 1.0460342287145432e-10 6.813858407828201e-10 651.3991818605837 3.6003162703801224e-10 8.343883659753289e-10 231.7541858308003 1.5703050905445814e-10 4.2870239235217056e-10 273.00579672928194 2.3061878033392332e-10 5.744765943724995e-10 249.10226024987605 3.913500542382847e-10 4.535327634320557e-10 115.88928084213556 6.815005267791294e-10 5.143421303311002e-10 75.4720077417924 3.6320000000001106e-10 4.9933518514664e-10 137.4821545007227 0.0003434177624328 0.0111198621648255 3237.99854907015 0.0002196765564157 0.008966490785647 4081.678505865216 +r_4724 polyphosphate phosphohydrolase, m 0.0027121565631247 0.0605651506895823 2233.099353962187 0.0064038807230614 0.1257911411423674 1964.295504277153 0.0132852925505063 0.215596707517063 1622.8224308756069 0.0207495982902681 0.3458483621356938 1666.771362498624 0.0445509616707541 0.6082349297736258 1365.256566780032 0.0227340116519686 0.4460326001020362 1961.961693916048 0.0415193398082399 0.7129553439656983 1717.164452177065 0.048408442247919 0.8570522625259485 1770.460322058371 0.0442830460982461 0.8115983605302429 1832.7518814528569 +r_4725 polyphosphate phosphohydrolase, n -7.79600000000035e-10 4.287897061759063e-10 -55.00124501999576 -5.414000000000241e-10 5.070872385433092e-10 -93.66221620673927 -7.350000000000386e-10 4.5256597661847687e-10 -61.57360226101402 -3.0620000000000655e-10 4.665673552868997e-10 -152.3734014653461 -2.2320000000000043e-10 4.2733860539008916e-10 -191.4599486514733 -2.7460000000000425e-10 4.5567133690131743e-10 -165.94003528816836 -2.720000000000041e-10 4.561333264762559e-10 -167.6960759103857 -2.6240000000000325e-10 4.5076255099052494e-10 -171.78450876163086 -1.7719999999999842e-10 3.9323159361533235e-10 -221.9139918822437 +r_4726 ethyl-(2S)-lactate transport 6.862221431584008e-05 0.0015330775987265 2234.083545702051 3.2913863632343884e-05 0.0007751847021741 2355.192057769924 5.3733138891004575e-05 0.0014352577855618 2671.0849490352243 8.272419416868286e-05 0.0019494732309412 2356.593800075022 0.0002040666617215 0.0048060704398551 2355.1472833976445 0.0001398739241495 0.0040358512732324 2885.3492870608006 0.0002045855251014 0.0059029427806496 2885.317901997972 0.0004136636650795 0.0103343978048314 2498.2609489874467 0.0004472667089893 0.0105337669020456 2355.1421758727765 +r_4727 ethyl-(2S)-lactate exchange 6.862221431584008e-05 0.0015330775987265 2234.083545702051 3.2913863632343884e-05 0.0007751847021741 2355.192057769924 5.3733138891004575e-05 0.0014352577855618 2671.084949035224 8.272419416868286e-05 0.0019494732309412 2356.593800075022 0.0002040666617215 0.0048060704398551 2355.1472833976445 0.0001398739241495 0.0040358512732324 2885.3492870608006 0.0002045855251014 0.0059029427806496 2885.317901997972 0.0004136636650795 0.0103343978048314 2498.2609489874467 0.0004472667089893 0.0105337669020456 2355.1421758727765 +r_4728 ethyl-(2R)-lactate transport 2.006811394565132e-05 0.0008558196931394 4264.574615517933 7.756093041041221e-07 5.4896054769533416e-05 7077.797349651683 1.7339877408929628e-05 0.0008669515226913 4999.75577823209 9.74543270249004e-06 0.0006891701609177 7071.724590963333 3.6021415855713938e-06 0.0002547488435731 7072.149651018087 6.947384664730294e-05 0.0028884482979345 4157.6052533815855 3.843660335464124e-05 0.0027179352637024 7071.216045353933 5.781513966776614e-05 0.004088207945193 7071.171960641995 7.1722395926758e-06 0.0005072188789283 7071.973438342975 +r_4729 ethyl-(2R)-lactate exchange 2.006811394565132e-05 0.0008558196931394 4264.574615517933 7.756093041041221e-07 5.4896054769533416e-05 7077.797349651683 1.7339877408929628e-05 0.0008669515226913 4999.75577823209 9.74543270249004e-06 0.0006891701609177 7071.724590963333 3.6021415855713938e-06 0.0002547488435731 7072.149651018087 6.947384664730294e-05 0.0028884482979345 4157.6052533815855 3.843660335464124e-05 0.0027179352637024 7071.216045353933 5.781513966776614e-05 0.004088207945193 7071.171960641995 7.1722395926758e-06 0.0005072188789283 7071.973438342975 +r_4730 diethyl-succinate transport -9.799999999999654e-10 1.4001400210035194e-10 -14.287143071464987 -9.993999999999583e-10 2.4489996978164182e-11 -2.450469979804403 -9.959999999999598e-10 6.312524819271919e-11 -6.337876324570456 -9.49799999999976e-10 2.1929336040013135e-10 -23.08837233103148 -9.929999999999611e-10 8.338099590491861e-11 -8.396877734634632 -9.733999999999675e-10 1.6092737344499402e-10 -16.532501894904392 -9.929999999999611e-10 8.338099590491689e-11 -8.396877734634462 -9.89599999999962e-10 1.0145885264360168e-10 -10.252511382741064 -9.951999999999601e-10 6.912246800510111e-11 -6.945585611445326 +r_4731 diethyl-succinate exchange -9.799999999999654e-10 1.4001400210035194e-10 -14.287143071464987 -9.993999999999583e-10 2.4489996978164182e-11 -2.450469979804403 -9.959999999999598e-10 6.312524819271919e-11 -6.337876324570456 -9.49799999999976e-10 2.1929336040013135e-10 -23.08837233103148 -9.929999999999611e-10 8.338099590491861e-11 -8.396877734634632 -9.733999999999675e-10 1.6092737344499402e-10 -16.532501894904392 -9.929999999999611e-10 8.338099590491689e-11 -8.396877734634462 -9.89599999999962e-10 1.0145885264360168e-10 -10.252511382741064 -9.951999999999601e-10 6.912246800510111e-11 -6.945585611445326 +r_4732 monoethyl-succinate transport -9.903999999999618e-10 9.751790578345163e-11 -9.846315204306888 -9.993999999999583e-10 2.4489996978164182e-11 -2.450469979804403 -9.99799999999958e-10 1.414213562372846e-11 -1.4144964616652378 -9.99799999999958e-10 1.4142135623729846e-11 -1.4144964616653766 -9.951999999999601e-10 6.912246800509976e-11 -6.945585611445189 -9.911999999999614e-10 9.340398739332948e-11 -9.423323990449266 -9.98399999999959e-10 3.997198458809068e-11 -4.003604225570144 -9.965999999999595e-10 5.821613026957997e-11 -5.841474038689778 -9.995999999999586e-10 1.999799949987206e-11 -2.000600190063314 +r_4733 monoethyl-succinate exchange -9.903999999999618e-10 9.751790578345163e-11 -9.846315204306888 -9.993999999999583e-10 2.4489996978164182e-11 -2.450469979804403 -9.99799999999958e-10 1.414213562372846e-11 -1.4144964616652378 -9.99799999999958e-10 1.4142135623729846e-11 -1.4144964616653766 -9.951999999999601e-10 6.912246800509976e-11 -6.945585611445189 -9.911999999999614e-10 9.340398739332948e-11 -9.423323990449266 -9.98399999999959e-10 3.997198458809068e-11 -4.003604225570144 -9.965999999999595e-10 5.821613026957997e-11 -5.841474038689778 -9.995999999999586e-10 1.999799949987206e-11 -2.000600190063314 +r_4734 ethyl-benzoate transport 9.335999999999816e-10 3.5385884645807135e-10 37.90261851521834 -9.017999999999923e-10 3.1396890816616277e-10 -34.81580263541421 -9.421999999999786e-10 3.3238720831470435e-10 -35.27777630171003 -9.711999999999683e-10 2.2886903724016782e-10 -23.56559279655841 -9.503999999999755e-10 2.9522410378270103e-10 -31.06314223302909 8.807999999999997e-10 4.6025398069472685e-10 52.25408500167199 -9.423999999999783e-10 3.2604217625966353e-10 -34.59700512093283 -6.814000000000348e-10 7.29383602837342e-10 -107.04191412346708 -9.52199999999975e-10 3.025449829254162e-10 -31.773260126593584 +r_4735 ethyl-benzoate exchange 9.335999999999816e-10 3.5385884645807135e-10 37.90261851521834 -9.017999999999923e-10 3.1396890816616277e-10 -34.81580263541421 -9.421999999999786e-10 3.3238720831470435e-10 -35.27777630171003 -9.711999999999683e-10 2.2886903724016782e-10 -23.56559279655841 -9.503999999999755e-10 2.9522410378270103e-10 -31.06314223302909 8.807999999999997e-10 4.6025398069472685e-10 52.25408500167199 -9.423999999999783e-10 3.2604217625966353e-10 -34.59700512093283 -6.814000000000348e-10 7.29383602837342e-10 -107.04191412346708 -9.52199999999975e-10 3.025449829254162e-10 -31.773260126593584 +r_4736 ethyl-pyruvate transport 0.0464013688063878 0.0165998900738629 35.774569804453144 0.0001301309937858 0.0021089579730801 1620.642332564153 0.2022466216008976 0.0362558835392811 17.92657066520822 0.0004432882132089 0.0051601377628536 1164.059320571547 0.1945696218974703 0.0865094032091792 44.46192697787424 0.4947393430786017 0.0602538952741418 12.178917265645689 0.2090348043274515 0.1004017919240181 48.03113636843912 0.689580606434669 0.232649343031546 33.73780249337498 0.7418552287917177 0.2181854710940872 29.41078833527298 +r_4737 ethyl-pyruvate exchange 0.0464013688063878 0.0165998900738629 35.774569804453144 0.0001301309937858 0.0021089579730801 1620.642332564153 0.2022466216008976 0.0362558835392811 17.92657066520822 0.0004432882132089 0.0051601377628536 1164.059320571547 0.1945696218974703 0.0865094032091792 44.46192697787424 0.4947393430786017 0.0602538952741418 12.178917265645689 0.2090348043274515 0.1004017919240181 48.03113636843912 0.689580606434669 0.232649343031546 33.73780249337498 0.7418552287917177 0.2181854710940872 29.41078833527298 +r_4738 benzyl-acetate transport 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4739 benzyl-acetate exchange 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4740 ethyl-isobutyrate transport 4.842286502114825e-05 0.0013972090752241 2885.4324803251025 1.7319807691746054e-05 0.0004997576772014 2885.468973420828 7.422380481524617e-05 0.0016611480251776 2238.025966618747 4.406892528951229e-05 0.0012715477449914 2885.361366627268 0.0001562712212602 0.0041740433817522 2671.0249962153584 0.0001838883962378 0.0045940063501943 2498.2578804224613 0.0002954027569026 0.0069571595341334 2355.143739036584 0.0003565119278462 0.0095224858043352 2671.0146451096343 0.0003424800820564 0.0091476968305475 2671.0157202777905 +r_4741 ethyl-isobutyrate exchange 4.842286502114825e-05 0.0013972090752241 2885.4324803251025 1.7319807691746057e-05 0.0004997576772014 2885.468973420827 7.422380481524617e-05 0.0016611480251776 2238.025966618747 4.406892528951229e-05 0.0012715477449914 2885.361366627268 0.0001562712212602 0.0041740433817522 2671.0249962153584 0.0001838883962378 0.0045940063501943 2498.2578804224613 0.0002954027569026 0.0069571595341334 2355.143739036584 0.0003565119278462 0.0095224858043352 2671.0146451096343 0.0003424800820564 0.0091476968305475 2671.0157202777905 +r_4742 ethyl-2-methylbutyrate transport 4.034221282381097e-05 0.0010775525317145 2671.0298129174066 1.2865520209608403e-05 0.0003730369779616 2899.509478699621 1.5381957562385894e-05 0.0006278806633049 4081.929499274548 3.987558636445398e-05 0.0010651031832355 2671.065883522747 6.04915423027279e-05 0.0021380899341373 3534.527064027202 4.966527444195708e-05 0.0019180201313099 3861.893753454413 6.790794954765106e-05 0.0027718158048747 4081.725075397479 0.0001380041384326 0.0048777471253833 3534.493371561777 0.0001325723424966 0.0046857666597314 3534.4978986482333 +r_4743 ethyl-2-methylbutyrate exchange 4.034221282381097e-05 0.0010775525317145 2671.0298129174066 1.2865520209608403e-05 0.0003730369779616 2899.509478699621 1.5381957562385894e-05 0.0006278806633049 4081.929499274548 3.987558636445398e-05 0.0010651031832355 2671.065883522747 6.04915423027279e-05 0.0021380899341373 3534.527064027202 4.966527444195708e-05 0.0019180201313099 3861.893753454413 6.790794954765106e-05 0.0027718158048747 4081.725075397479 0.0001380041384326 0.0048777471253833 3534.493371561777 0.0001325723424966 0.0046857666597314 3534.4978986482333 +r_4744 polyphosphate transport, v-c 4.181943532519194e-05 0.001104717293731 2641.6360841331825 3.225243060677898e-05 0.0013164294713862 4081.64422531785 3.633323483793991e-05 0.0012841899336082 3534.4772887308104 4.025465300756734e-05 0.0016430669737432 4081.6821186718153 5.357883284674489e-05 0.0026786913553384 4999.532862166855 6.565700915124866e-05 0.0026799180975031 4081.6938391599138 0.0001610600331024 0.0056926352781469 3534.480385040841 0.0002215473575866 0.0079553394911565 3590.8076619894223 0.0001174215786945 0.0058705216860575 4999.525429075035 +r_4745 polyphosphate transport, c-m 0.0027121565631247 0.0605651506895823 2233.099353962187 0.0064038807230614 0.1257911411423674 1964.295504277153 0.0132852925505063 0.215596707517063 1622.8224308756069 0.0207495982902681 0.3458483621356938 1666.771362498624 0.0445509616707541 0.6082349297736258 1365.256566780032 0.0227340116519686 0.4460326001020362 1961.961693916048 0.0415193398082399 0.7129553439656983 1717.164452177065 0.048408442247919 0.8570522625259485 1770.460322058371 0.0442830460982461 0.8115983605302429 1832.7518814528569 +r_4746 polyphosphate transport, c-n -7.79600000000035e-10 4.287897061759063e-10 -55.00124501999576 -5.414000000000241e-10 5.070872385433092e-10 -93.66221620673927 -7.350000000000386e-10 4.5256597661847687e-10 -61.57360226101402 -3.0620000000000655e-10 4.665673552868997e-10 -152.3734014653461 -2.2320000000000043e-10 4.2733860539008916e-10 -191.4599486514733 -2.7460000000000425e-10 4.5567133690131743e-10 -165.94003528816836 -2.720000000000041e-10 4.561333264762559e-10 -167.6960759103857 -2.6240000000000325e-10 4.5076255099052494e-10 -171.78450876163086 -1.7719999999999842e-10 3.9323159361533235e-10 -221.9139918822437 +r_4747 cytidine kinase (ATP) 0.0001033507883769 0.0027605014171372 2671.0017992986154 0.0001343825840106 0.0042478246846625 3160.993454573992 0.0001361791837029 0.0039291869129967 2885.3065543162 0.000234818655456 0.0062720189386202 2671.0053877279806 0.0002678956870785 0.0094686849096377 3534.467095344789 0.0002736041754667 0.0086486562669737 3161.0103362714185 0.0007046860646005 0.018822215847651 2671.007246087812 0.0007639560680467 0.0241487400054099 3161.011609889271 0.0007338183454328 0.0231960778804384 3161.0108993329554 +r_4748 D-glyceraldehyde kinase 9.999239432012584e-12 6.713261095267676e-10 6713.771723252432 1.3896856796261367e-10 7.070549615915443e-10 508.78768627864224 3.9927488205224527e-10 6.42968553982134e-10 161.0340602136854 3.324777719151259e-11 6.71169233120353e-10 2018.6890367266049 1.3230876573205607e-10 5.821538329824493e-10 439.9964203138236 -6.366666666848212e-11 6.123537429584583e-10 -961.8121616874296 8.673333333333409e-11 6.504748326769049e-10 749.9709831017285 6.940000000000035e-11 6.23106164516509e-10 897.8474993033229 2.1160066507598808e-11 6.4582234967421e-10 3052.0809064673235 +r_4749 adenosine phosphorylase -2.0438705099186147e-05 0.0016379983662183 -8014.1983470547875 1.6554574979351963e-05 0.0032593546246228 19688.543068536528 2.2415668212096693e-05 0.0029298194526561 13070.408720071431 7.012293501051453e-05 0.004479001727771 6387.356329422699 0.0001509570430562 0.009512383022221 6301.384042527883 -6.079265169108967e-05 0.0065164421008775 -10719.12792024617 0.000429043982709 0.0147693412912296 3442.3839714460946 0.0001732194666534 0.0193951729254972 11196.878330248754 0.0004481618294406 0.0215404580161136 4806.401750679226 +r_4750 D-glucose 1-epimerase 0.0 0.0 0.0 0.0 -4e-12 9.157334293028108e-11 -2289.333573257027 -6.399999999999999e-12 1.0373616649196217e-10 -1620.8776014369096 -8.200000000000003e-12 1.0646608382673372e-10 -1298.3668759357768 0.0 0.0 -4.6e-12 7.334791055780814e-11 -1594.5197947349595 -2.800000000000001e-12 6.318986146304394e-11 -2256.780766537283 -6.000000000000003e-13 3.1620246172249993e-11 -5270.041028708331 +r_4751 D-phenylalanine N-acetyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4752 S-adenosylmethioninamine:cadaverine 3-aminopropyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4753 thiamine phosphate synthase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4754 flavin prenyltransferase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4755 (R)-2-hydroxyglutarate:pyruvate oxidoreductase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4756 cytidine nucleosidase 9.768195450521577e-06 0.0003986980158365 4081.5933491096575 1.1777384228362967e-05 0.000588802841514 4999.4364631158605 1.6381511316066193e-05 0.0006686314945464 4081.622761452511 1.614725443228534e-05 0.0008072715745045 4999.435525648501 8.913414518886963e-06 0.0006302661181418 7070.98404103569 2.643075569333277e-05 0.0013214074461192 4999.506867874299 3.477276897263079e-05 0.0018252424291991 5249.0569003456085 3.4100205144499114e-05 0.0024112273144382 7071.005303987728 3.318944530123791e-05 0.0023468372870199 7071.03498030575 +r_4757 D-ribulokinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4758 deoxyguanosine phosphorylase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4760 trans-4-hydroxy-L-proline dehydrogenase 0.000390870274707 0.0089073431385694 2278.8489468135804 0.0004031452092375 0.0127434712241912 3161.012690264343 0.000401903223854 0.0116045579309335 2887.4010563172405 0.0007044549424921 0.0188160530967121 2671.008741899982 0.0015801256817717 0.0394963790237537 2499.571994771227 0.0006566495332658 0.02320910124601 3534.473120018519 0.0021025820140802 0.0561651613864891 2671.2471147556325 0.0027502415891088 0.0793529234642298 2885.30737730361 0.0026252155024108 0.0757532828828036 2885.6024510458888 +r_4761 3-hydroxykynurenine aminotransferase (2-oxoglutarate) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4762 (S)-3-hydroxyisobutyryl-CoA hydrolase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4763 meso-2,3-butanediol dehydrogenase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4764 5-methylcytosine deaminase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4765 ureidoglycolate hydrolase 1.1425002274342856e-10 4.488279802616224e-10 392.84716929077206 -4.719259005712904e-10 7.63179590736377e-10 -161.7159791002166 -7.295085036606263e-10 8.863863821764132e-10 -121.50459901818608 -1.1348607691432306e-09 9.620869493832851e-10 -84.77576946373941 -7.14094940832377e-10 8.211696175275854e-10 -114.99445950007689 8.923587956529903e-11 7.99719376636092e-10 896.1859069825061 -1.0504352534394003e-09 1.0216395906928066e-09 -97.25869227519648 -7.947199532520643e-10 1.0218281720491043e-09 -128.57713813119867 -1.1059567640588702e-09 1.027223829820442e-09 -92.88101155514636 +r_4766 guanylate cyclase 4.429305766028359e-05 0.0014001089753928 3161.0122428921068 8.062876411681367e-05 0.0025486850797622 3161.012211559808 5.449955313032671e-05 0.0019262718158499 3534.472679516499 0.0001006361219772 0.0031811201365266 3161.0122429470475 0.0001342927357804 0.0049623762382455 3695.1933471362886 0.0001313299679502 0.0046418220931276 3534.4728743760647 0.0003020073127656 0.0095464881311463 3161.0122429564112 0.0003650884556442 0.0129043294169266 3534.57613283232 0.000264199718947 0.010783747611429 4081.665057936285 +r_4767 kynurenine aminotransferase (2-oxoglutarate) 2.54996465096473e-10 3.2135693324355587e-09 1260.240737541113 2.6053186601927497e-10 1.941283131970223e-09 745.1231059108143 1.4130044491057155e-10 1.4346796668935222e-09 1015.339808591208 1.7875953610863516e-10 1.4772399979200415e-09 826.3838842266285 1.5522060362340022e-10 1.290528110565743e-09 831.4154696220946 2.0430016213314047e-10 1.0536409671082664e-09 515.7318310993893 7.574878217226732e-10 3.1030238143109904e-09 409.6466933625569 4.4577818065972136e-11 3.9413180993309366e-10 884.1433408647445 7.92432244804832e-10 2.958639838220621e-09 373.3618688054906 +r_4768 farnesyl diphosphatase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4769 bis(5'-adenosyl)-triphosphatase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4770 nucleoside diphosphate kinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4771 nucleoside diphosphate kinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4772 nucleoside diphosphate kinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4773 nucleoside diphosphate kinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4774 nucleoside diphosphate kinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4775 nucleoside diphosphate kinase 2.9528733202568208e-05 0.0014762891295872 4999.500383100967 0.000107505407334 0.003799750050167 3534.473422680417 6.812440579914295e-05 0.0027806123303996 4081.6683797550736 6.709120243151129e-05 0.0033542139361957 4999.484007787557 0.000267790106804 0.0094649716158136 3534.473968726402 0.0002215015750387 0.0077385119185122 3493.6599963950707 0.0003020082841351 0.0123269711274785 4081.666555200105 0.0009162750721992 0.0264373705446822 2885.309373442636 0.0007665828081191 0.0233121751637508 3041.051131964381 +r_4776 nucleoside diphosphate kinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4777 nucleoside diphosphate kinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4778 nucleoside diphosphate kinase 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 +r_4779 heme a transport, cytoplasm-extracellular 1.393558492793553e-05 0.0001439642929897 1033.0696108865266 7.968883217208883e-06 0.0001060046036848 1330.2316120770463 1.4335179957169267e-05 0.0001678546758252 1170.9282780317312 1.380196671174206e-05 0.000203093535253 1471.482575597646 4.5141860032553176e-05 0.0005130161765609 1136.4533410697 3.8373615815494335e-05 0.0004661301530399 1214.715223296029 4.036684817972119e-05 0.0005824694768369 1442.940192515622 9.318814551168528e-05 0.0011187945680174 1200.5760624104291 9.23442423217436e-05 0.0010814233936429 1171.0783113852494 +r_4780 heme a exchange 1.393558492793553e-05 0.0001439642929897 1033.0696108865266 7.968883217208883e-06 0.0001060046036848 1330.2316120770463 1.4335179957169267e-05 0.0001678546758252 1170.9282780317312 1.380196671174206e-05 0.000203093535253 1471.482575597646 4.5141860032553176e-05 0.0005130161765609 1136.4533410697 3.8373615815494335e-05 0.0004661301530399 1214.715223296029 4.036684817972119e-05 0.0005824694768369 1442.940192515622 9.318814551168528e-05 0.0011187945680174 1200.5760624104291 9.23442423217436e-05 0.0010814233936429 1171.0783113852494 +r_4781 HET-P synthase (thiazole synthase) 2.70543021022721e-08 8.012374478084223e-09 29.615897862733338 3.7715204760483534e-08 1.8678517620277876e-08 49.52516561662279 1.0524919081847542e-07 9.654360777910171e-10 0.9172859860330104 1.5554149108442257e-07 1.550793243534041e-09 0.9970286595056004 2.204889798918316e-07 2.2638629417803726e-09 1.0267465262395372 2.6010675232153804e-07 1.444959934345244e-09 0.5555257298968607 2.923726969060619e-07 3.267505172131974e-09 1.1175821842153095 3.45884277045504e-07 3.389403563848888e-09 0.9799241505860596 3.898471111611594e-07 2.6901541170641747e-09 0.6900536235991469 +r_4782 adenylated thiazole synthase 2.70543021022721e-08 8.012374478084223e-09 29.615897862733338 3.7715204760481535e-08 1.867851762028045e-08 49.52516561663225 1.0524919081847542e-07 9.654360777910171e-10 0.9172859860330104 1.5554149108442257e-07 1.550793243534041e-09 0.9970286595056004 2.204889798918316e-07 2.2638629417803726e-09 1.0267465262395372 2.6010675232153804e-07 1.444959934345244e-09 0.5555257298968607 2.923726969060619e-07 3.267505172131974e-09 1.1175821842153095 3.45884277045504e-07 3.389403563848888e-09 0.9799241505860596 3.898471111611594e-07 2.6901541170641747e-09 0.6900536235991469 +r_4783 oxaloacetate/sulphate antiport, mitochondrial 0.0289446653062685 0.1238586578220149 427.91532225867866 0.0473797377699201 0.1916153641812755 404.4247038929917 0.103784561309013 0.3509018946715775 338.1060634122505 0.1031733681381262 0.5772256421898652 559.4715502716632 0.1670206118367372 0.7329819160655024 438.8571614035234 0.2900352531459723 0.8412977364683136 290.0674064076257 0.2267114693950197 1.16665222614235 514.5977965982776 0.2472392989127641 1.286102257147789 520.1852063176966 0.3090878438545075 1.0862117519294852 351.42493421410063 +r_4784 malate/sulphate antiport, mitochondrial -0.0289446653062685 0.1238586578220149 -427.91532225867866 -0.0473797377699201 0.1916153641812755 -404.4247038929917 -0.103784561309013 0.3509018946715775 -338.1060634122505 -0.1031733681381262 0.5772256421898652 -559.4715502716632 -0.1670206118367372 0.7329819160655024 -438.8571614035234 -0.2900352531459723 0.8412977364683136 -290.0674064076257 -0.2267114693950197 1.16665222614235 -514.5977965982776 -0.2472392989127641 1.286102257147789 -520.1852063176966 -0.3090878438545075 1.0862117519294852 -351.42493421410063 +r_4785 acetate transport 0.032742347336402 0.0071220721877134 21.7518680458054 0.0528116088863356 0.0121870156419172 23.07639532086004 0.1183928797982387 0.0174441313519398 14.734105109756236 0.175687733783265 0.0275082215217635 15.65745139367484 0.2502198937687939 0.0417438175832851 16.682853211446456 0.2940813052891792 0.04663629809767 15.85830083684208 0.3335773060517899 0.0561582465268946 16.83515200466777 0.3942604459572246 0.0791023966717444 20.06348784993934 0.4420963014663993 0.0861271558171798 19.481537287578004 +r_4786 ribonucleotide reductase 2.685034022098629e-06 0.0001084266253516 4038.184412534608 3.849511774048798e-06 0.0001661947383252 4317.29393440493 3.397771099045377e-06 0.0001618912640842 4764.63126458708 4.667448963114076e-06 0.0002347716314531 5029.977473958189 9.186545160433128e-06 0.0004692970446425 5108.525963207831 1.1633575641974765e-05 0.0004202279348591 3612.199273824111 1.5615005184873783e-05 0.0007042178781743 4509.879246511756 4.402199289963661e-05 0.0015284194923124 3471.945251994911 3.348370598326621e-05 0.0014392714892479 4298.423507741986 +r_4787 ribonucleotide reductase 4.1228818099388247e-10 1.091971696860201e-09 264.8564152937491 1.6218150369738354e-10 1.4507773086194823e-09 894.5393127729938 3.2182260263402864e-10 1.27612483859581e-09 396.5305196561966 -1.6098090902377107e-10 1.5519962447830427e-09 -964.0871418820656 4.5349524942346367e-10 1.0883859481572428e-09 239.99941554865825 -9.452948200420412e-10 1.785943839129579e-09 -188.9298239305015 -5.118999999999815e-10 1.672294143845759e-09 -326.68375539086145 -4.2500000000001165e-11 1.500164607224701e-09 -3529.79907582273 5.004386162749521e-10 9.922284130868459e-10 198.27175218262803 diff --git a/literature/xia2022/results/randomSampling/selectedFluxes.tsv b/literature/xia2022/results/randomSampling/selectedFluxes.tsv new file mode 100644 index 0000000..f5a58bc --- /dev/null +++ b/literature/xia2022/results/randomSampling/selectedFluxes.tsv @@ -0,0 +1,45 @@ +Row mu003 mu004 mu010 mu015 mu021 mu025 mu028 mu033 mu038 +rGlu 0.3730299360838871 0.5695554500263653 1.3101497120401149 1.8564468044982183 2.705567238071132 3.128006167774593 3.593461172180393 5.565805480213094 7.674218123681864 +ETC_rATP 2.789755094146721 5.022169681862444 7.8419754984552625 13.163065654703033 18.07693299815211 19.503244035170667 25.90639154011047 31.53082595432204 30.270244771483306 +ETC_YATP_glu 7.478635959981935 8.81770103618526 5.985556785143309 7.090462071312027 6.681383757085858 6.235040146690685 7.20931444610304 5.665096645295415 3.9444076625959297 +ETC_YATP_mu 103.32426274617484 114.14022004232828 76.69413690420795 86.59911614936205 84.37308283851627 76.78442533531758 91.13946012351968 94.47438488186376 79.97422660893874 +glycolysis_rATP 0.4223651728031219 0.5944638062383629 1.4536809948275446 2.025394280672023 2.7777173651650555 3.467492680450629 3.9636394614778654 7.418725954677164 10.936766014043652 +glycolysis_YATP_glu 1.1322554356820849 1.0437329784322924 1.109553344528793 1.0910058267031624 1.0266672829559251 1.108531279820833 1.10301441188882 1.3329114682594203 1.4251309824376628 +glycolysis_YATP_mu 15.643154548263777 13.510541050871886 14.216929044768165 13.324962372842256 12.964841844410994 13.6515459860261 13.944202151197418 22.22839237356454 28.89502249417082 +GAEC_rATP 1.209487861919706 1.982426767367212 4.729874282258439 7.183773767055699 9.685185071107153 11.7875505587985 13.274042899136267 15.784796512706087 17.6760797718252 +GAEC_YATP_glu 3.2423345820902587 3.4806563035705174 3.6101784695225865 3.869636204845316 3.579724404857876 3.7683910857454297 3.693943600086826 2.836030933675703 2.303306928073702 +GAEC_YATP_mu 44.795846737766894 45.05515380380026 46.25793919079159 47.26166952010329 45.20506450925158 46.40767936534842 46.69847985624017 47.295270450055696 46.700342858190766 +NGAM_rATP 1.402644910835488 2.5532822293319803 2.15732013678463 3.1869246918126346 6.362718403456992 5.198535744544199 9.563804267398806 14.51548224843692 13.94432242255514 +NGAM_YATP_glu 3.760140340372202 4.4829388064213695 1.6466210822771807 1.716679779938016 2.351713279908407 1.661932702723114 2.6614463908610446 2.607975125979641 1.817034934089815 +NGAM_YATP_mu 51.94981151242548 58.02914157572683 21.098485445326464 20.966609814556808 29.69763548871408 20.466676159622832 33.64574940157891 43.4920816432567 36.84101036342178 +Metabolism_rATP 0.5999874941946493 1.0809244914016145 2.4084620742397376 4.817761476506719 4.806746888753024 5.984650412278598 7.032183835053262 8.649273147856189 9.586608591146614 +Metabolism_YATP_glu 1.6084164732015604 1.8978389046256643 1.838310577872336 2.5951519132318577 1.7766133552755008 1.913247638042975 1.956938867043989 1.5540020538994903 1.249196782870076 +Metabolism_YATP_mu 22.22175904424627 24.566465713673058 23.55464131285807 31.695799187544207 22.435224684961604 23.56161579637244 24.73943301689802 25.915425162115923 25.327895881497007 +GAEC+NGAM+Metabolism_rATP 3.212120266949843 5.616633488100806 9.295656493282808 15.188459935375054 20.85465036331717 22.970736715621296 29.870031001588337 38.9495519089992 41.20701078552696 +GAEC+NGAM+Metabolism_YATP_glu 8.610891395664021 9.861434014617553 7.095110129672102 8.181467898015189 7.708051040041785 7.343571426511518 8.31232885799186 6.998008113554834 5.369538645033593 +GAEC+NGAM+Metabolism_YATP_mu 118.96741729443865 127.65076109320016 90.91106594897612 99.9240785222043 97.33792468292728 90.43597132134369 105.0836622747171 116.70277725542832 108.86924910310957 +rPDH 0.3373382673341216 0.6230043196500415 1.033248283606257 1.6675365633096388 2.4771614139187745 2.422516669873273 3.436177962702028 3.9562532535285646 4.3372378907576365 +rIDH 0.2935851269145126 0.6028683332763447 0.6410873738221198 1.4014670330075096 1.6483403291905931 1.773424407220941 2.3331633169581925 3.11572311831835 2.117527554380613 +rMDHc 0.0129634670563507 0.0204174893026789 0.0281765498408505 -0.0241724705979308 0.0316886803201147 0.096223213236944 7.031462811301913e-05 -0.0373234991432006 0.006330351378209 +rMDHm 0.2490846924019438 0.480845566875574 0.7054681044747447 1.223019351348799 1.8507159143933696 1.5725777171149842 2.572453148603946 2.9449742390371925 3.181114182077761 +rNDE 0.5128320889858105 0.8484656326356158 1.8001047749673145 2.7574209674541192 3.7157945884653576 4.294989162640974 5.127009468168347 6.490125298075176 12.81145094033337 +rNAD[c] 0.5908497388966198 0.8850067518545288 2.0899177395181363 2.9212301203026603 4.083982268499798 5.0080155487994364 5.625028124260826 9.382325548163813 13.16058459417808 +rNAD[m] 1.1447634813403489 2.1439319926782154 2.973216352814238 5.260468276004747 7.253238054939706 7.475351885320856 10.443788158212143 12.590873000567756 11.471065467624667 +rNAD[n] 8.755184442741689e-10 1.4091186001621695e-09 1.3398191461503442e-09 1.2553999999954795e-09 5.483252843425971e-10 1.497492906341907e-09 1.3988817999999915e-09 1.5504251999999211e-09 1.6954194000000227e-09 +rNAD[p] 0.0010317580894008 0.0021560117290827 0.0016822741602906 0.0026456021713067 0.0049836245927692 0.0041877797592582 0.007589850296055 0.0120344210398921 0.010943757884707 +rNAD[erm] 0.0054241825618801 0.0088111905626976 0.0203003969206968 0.0301813184176421 0.0427081258890994 0.0505052514494625 0.056781495181828 0.0667838273211041 0.0756086973761338 +rNAD[tot] 1.7420691617637682 3.0399059482336432 5.085116764753181 8.214525318151754 11.384912074469698 12.538060466826508 16.133187629349734 22.05201679864299 24.718202518759007 +rNADP[c] 0.3050371599851215 0.62595618309264 1.319826785081207 2.212373397375247 3.181904618246667 2.8836520424875376 3.9763949533688048 4.846891199018559 6.030650769615515 +rNADP[er] 0.0017022385166899 0.0027496141003778 0.0063712938165576 0.0094743377749385 0.013389895027488 0.0158440916804681 0.017778361073332 0.020903324379955 0.02366510716884 +rNADP[m] 0.0180498007568999 0.029207505011498 0.0800617539906895 0.1335318838882391 0.1456662383678431 0.2027770146722384 0.2358810524277818 0.2980844993394431 0.3146504963323029 +rNADP[p] 4.1468842661407154e-05 7.524246414415266e-05 6.658079450419747e-05 0.0001016876279765 0.0002184397901925 0.0001820772748804 0.0004249476064617 0.0004706324047729 0.0004876144501209 +rNADP[erm] 0.0011834707076126 0.0027272483067606 0.0019663578895989 0.0029091596724345 0.0051445345673541 0.0051261650574926 0.0085633064429112 0.0140345018013213 0.0122172176512269 +rNADP[lp] 8.518412860482486e-05 0.0001340110731005 0.0001300641124587 0.0001348547787696 0.0002751006036738 0.0003824952233237 0.0005903706699503 0.0009211490221598 0.00085597196722 +rNADP[tot] 0.3260993229375902 0.6608498040485213 1.408422835685016 2.3585253211176056 3.3465988266032185 3.107963886395941 4.239632991589242 5.181305305966212 6.382527177185226 +GAECpol_protein 11.2723 11.762400000000005 13.986700000000004 15.7963 12.064000000000002 14.250600000000004 14.7407 15.7963 14.7407 +GAECpol_carbohydrate 6.478658490559815 6.312258490559815 5.557058490559815 4.9426584905598165 6.209858490559816 5.467458490559816 5.301058490559816 4.9426584905598165 5.301058490559816 +GAECpol_RNA 1.4075829645596514 1.4075829645596514 1.4075829645596514 1.4075829645596514 1.4075829645596514 1.4075829645596514 1.4075829645596514 1.4075829645596514 1.4075829645596514 +GAECpol_DNA 0.085132414342395 0.085132414342395 0.085132414342395 0.085132414342395 0.085132414342395 0.085132414342395 0.085132414342395 0.085132414342395 0.085132414342395 +GAECpol_total 19.243673869461865 19.567373869461864 21.036473869461865 22.231673869461865 19.766573869461865 21.210773869461867 21.534473869461863 22.231673869461865 21.534473869461863 +GAECpol_GAEC_noPol 34.0 34.0 34.0 34.0 34.0 34.0 34.0 34.0 34.0 +GAECpol_GAEC_total 53.24367386946186 53.56737386946186 55.036473869461865 56.231673869461865 53.766573869461865 55.21077386946187 55.53447386946186 56.231673869461865 55.53447386946186 diff --git a/literature/xia2022/scripts/prepare_data.py b/literature/xia2022/scripts/prepare_data.py new file mode 100644 index 0000000..f71f188 --- /dev/null +++ b/literature/xia2022/scripts/prepare_data.py @@ -0,0 +1,97 @@ +"""Write the chemostat series in the overflow pipeline's data formats. + +Proteomics in copies/cell are converted per sample to mmol/gDW by scaling the +sample's total protein mass to Ptot: mmol/gDW_i = 1000 * Ptot * c_i / sum_j(c_j * MW_j). +Protein groups ("A:B") are assigned to the first member with a mass in +data/uniprot.tsv, isoform suffixes stripped. Byproducts not in the flux sheet are NA. +Ptot is the total protein content of Supplementary Table 6 of the paper. + +usage: prepare_data.py PROTEOMICS.xlsx FLUXES.xlsx OVERFLOW_REPO OUT_DIR +""" +import sys +from pathlib import Path + +import numpy as np +import openpyxl +import pandas as pd + +prot_xlsx, flux_xlsx, repo, out = sys.argv[1:5] +out = Path(out) + +# condition -> (row of the flux sheet by mu, proteomics sample columns, Ptot [g/gDW]) +CONDITIONS = { + "mu003": (0.027, ["S1", "S2", "S3"], 0.299), + "mu004": (0.044, ["S4", "S5", "S6"], 0.312), + "mu010": (0.10225, ["S7", "S8", "S9"], 0.371), + "mu015": (0.152, ["S10", "S11", "S12"], 0.419), + "mu021": (0.21425, ["S13", "S14", "S15"], 0.320), + "mu025": (0.254, ["S16", "S17", "S18"], 0.378), + "mu028": (0.28425, ["S19", "S20", "S21"], 0.391), + "mu033": (0.33375, ["S22", "S23", "S24"], 0.419), + "mu038": (0.3785, ["S25", "S26", "S27"], 0.391), +} + + +def sheet(path): + wb = openpyxl.load_workbook(path, read_only=True, data_only=True) + return list(wb.worksheets[0].iter_rows(values_only=True)) + + +# --- fermentation data ------------------------------------------------- +rows = sheet(flux_xlsx) +flux = pd.DataFrame(rows[2:], columns=rows[0]).dropna(subset=["mu"]) +records = [] +for name, (mu, _, ptot) in CONDITIONS.items(): + row = flux.loc[np.isclose(flux["mu"].astype(float), mu)] + assert len(row) == 1, (name, mu) + row = row.iloc[0] + etoh = float(row["qEthanol"]) + records.append({ + "Condition": name, "Ptot": ptot, "D": float(row["mu"]), + "Glucose": float(row["qGluc"]), "CO2": float(row["qCO2"]), + "Oxygen": float(row["qO2"]), "Glycerol": np.nan, "Acetate": np.nan, + "Ethanol": etoh if etoh > 0 else np.nan, "Formate": np.nan, + }) +pd.DataFrame(records).to_csv(out / "fermentationData.txt", sep="\t", index=False, na_rep="NA") + +# --- proteomics -------------------------------------------------------- +rows = sheet(prot_xlsx) +prot = pd.DataFrame(rows[2:], columns=rows[0]).dropna(subset=["Majority protein IDs"]) +uni = pd.read_csv(Path(repo) / "data" / "uniprot.tsv", sep="\t") +mass = dict(zip(uni["Entry"], uni["Mass"])) +gene = dict(zip(uni["Entry"], uni["Gene Names (ordered locus)"])) if "Gene Names (ordered locus)" in uni else {} + + +def resolve(group): + for member in group.split(":"): + member = member.split("-")[0] + if member in mass and not pd.isna(mass[member]): + return member + return None + + +prot["id"] = prot["Majority protein IDs"].map(resolve) +unresolved = prot[prot["id"].isna()] +samples = [s for _, cols, _ in CONDITIONS.values() for s in cols] +prot[samples] = prot[samples].apply(pd.to_numeric, errors="coerce") +prot = prot.dropna(subset=["id"]) +# isoform groups that resolve onto an already listed protein are summed +n_merged = prot["id"].duplicated().sum() +table = prot.groupby("id", sort=False).agg( + {"Gene Name": "first", **{s: lambda v: v.sum(min_count=1) for s in samples}} +) +mw = table.index.map(mass).to_numpy(dtype=float) + +orf = [gene.get(p) if isinstance(gene.get(p), str) else g for p, g in zip(table.index, table["Gene Name"])] +out_table = pd.DataFrame({"Protein.IDs": table.index, "Gene": [o.split()[0] for o in orf]}) +for name, (_, cols, ptot) in CONDITIONS.items(): + for k, s in enumerate(cols, start=1): + copies = table[s].to_numpy(dtype=float) + total_mg = np.nansum(copies * mw) # per cell, in copies * mg/mmol + out_table[f"{name}_{k}_abs"] = 1000.0 * ptot * copies / total_mg +out_table.to_csv(out / "abs_proteomics.txt", sep="\t", index=False, na_rep="NA", float_format="%.6E") + +print(f"proteins: {len(rows) - 2} rows, {len(unresolved)} without a mass dropped, " + f"{n_merged} isoform rows merged, {len(out_table)} written") +if len(unresolved): + print("dropped:", ", ".join(unresolved["Majority protein IDs"].astype(str))) diff --git a/literature/xia2022/scripts/run_step.py b/literature/xia2022/scripts/run_step.py new file mode 100644 index 0000000..cf36deb --- /dev/null +++ b/literature/xia2022/scripts/run_step.py @@ -0,0 +1,94 @@ +"""Run one overflow CLI step on the Xia et al. (2022) chemostat series. + +Points overflow.config at this folder's data/, models/ and results/ and at its +condition names before the step's module is imported, then calls its main(). + +usage: python literature/xia2022/scripts/run_step.py [args...] +""" +import importlib +import sys +from pathlib import Path + +RUN = Path(__file__).resolve().parents[1] +DATA = RUN / "data" +NAMES = ("mu003", "mu004", "mu010", "mu015", "mu021", "mu025", "mu028", "mu033", "mu038") + +import overflow.config as config # noqa: E402 + +# the package of this checkout, not another installed copy +assert config.ROOT == RUN.parents[1], f"overflow imported from {config.ROOT}" + +config.CONDITION_ORDER = NAMES +config.REPLICATE_PREFIX.clear() +config.REPLICATE_PREFIX.update({name: f"{name}_" for name in NAMES}) +config.FERMENTATION_DATA = DATA / "fermentationData.txt" +config.PROTEOMICS_DATA = DATA / "abs_proteomics.txt" +# so a step run without --models-dir/--results-dir cannot write into the repo +config.MODELS_DIR = RUN / "models" +config.RESULTS_DIR = RUN / "results" +config.load_conditions.__defaults__ = (config.FERMENTATION_DATA,) + +import overflow.proteomics as proteomics # noqa: E402 + +proteomics.read_proteomics.__defaults__ = (config.PROTEOMICS_DATA,) + +#: The core ribosome: the 48 subunits of this study, with the paralog this +#: dataset quantifies at the seven positions where it measures the other one +#: (data/ribosome_core.tsv). Re-selecting the core by abundance on this +#: dataset gives 77 subunits, as the paralog groups it quantifies cross the +#: threshold. +CORE = DATA / "ribosome_core.tsv" + + +def core_ids() -> list[str]: + import pandas as pd + + return pd.read_csv(CORE, sep="\t")["uniprot"].tolist() + + +def fixed_core(ribosome_table, proteomics_table, threshold=None): + """Stands in for overflow.ribosome.core_subunits.""" + from overflow.ribosome import RibosomeSubunits, _average_abundance + + core = core_ids() + rows = ribosome_table.set_index(ribosome_table["uniprot"].astype(str)) + value_columns = [c for c in proteomics_table.columns if c.endswith("_abs")] + measured = proteomics_table.set_index("Protein.IDs")[value_columns] + means = {u: _average_abundance(measured, u) for u in core if u in measured.index} + return RibosomeSubunits( + uniprot_ids=core, + genes={u: str(rows.loc[u, "gene"]) for u in core}, + masses={u: float(rows.loc[u, "mass"]) for u in core}, + mean_abundance={u: m for u, m in means.items() if m is not None}, + n_candidates=len(ribosome_table), + ) + + +def mark_core(argv: list[str]) -> None: + """The step marks the core by the abundance threshold; mark the one used.""" + import argparse + + import pandas as pd + + parser = argparse.ArgumentParser(add_help=False) + parser.add_argument("--results-dir", type=Path, default=config.RESULTS_DIR) + results_dir = parser.parse_known_args(argv)[0].results_dir + path = results_dir / "modelGeneration" / "averageRiboSubunitAbundance.tsv" + table = pd.read_csv(path, sep="\t") + table["core"] = table["uniprot"].isin(core_ids()) + table.to_csv(path, sep="\t", index=False) + + +# A forkserver worker re-imports this file; it must not run the step again. +if __name__ == "__main__": + step = sys.argv[1] + # the step must bind the patched names, so it cannot have been imported yet + assert f"overflow.{step}" not in sys.modules + module = importlib.import_module(f"overflow.{step}") + assert getattr(module, "CONDITION_ORDER", NAMES) == NAMES + if step == "build_ribosome": + module.core_subunits = fixed_core + status = module.main(sys.argv[2:]) + if step == "build_ribosome": + mark_core(sys.argv[2:]) + raise SystemExit(status) diff --git a/results/COMPARISON.md b/results/COMPARISON.md index c99f42d..a634166 100644 --- a/results/COMPARISON.md +++ b/results/COMPARISON.md @@ -11,25 +11,25 @@ deviation over glucose, CO2 and oxygen together. | condition | glucose | CO2 | oxygen | ethanol | residual G2 | residual G4 | |---|---|---|---|---|---|---| | CN4 | 1.115 / 1.183 / 1.205 | 3.088 / 2.964 / 3.101 | 2.928 / 2.630 / 2.730 | 0.000 / 0.000 / 0.000 | 0.125 | 0.105 | -| CN22 | 1.478 / 1.567 / 1.596 | 4.070 / 3.486 / 4.395 | 4.185 / 2.502 / 3.850 | 0.000 / 0.000 / 0.010 | 0.431 | 0.139 | +| CN22 | 1.478 / 1.567 / 1.596 | 4.070 / 3.486 / 4.395 | 4.185 / 2.502 / 3.850 | 0.000 / 0.000 / 0.000 | 0.431 | 0.139 | | CN38 | 2.014 / 2.135 / 2.175 | 6.303 / 4.140 / 5.799 | 5.169 / 1.831 / 4.954 | 0.790 / 0.870 / 0.747 | 0.734 | 0.120 | | CN75 | 3.227 / 3.392 / 3.486 | 7.880 / 6.061 / 8.511 | 6.661 / 1.100 / 6.128 | 2.283 / 2.511 / 2.100 | 0.868 | 0.139 | -| hGR | 5.416 / 5.668 / 5.849 | 11.033 / 11.534 / 11.916 | 7.660 / 5.591 / 8.167 | 3.680 / 4.048 / 3.386 | 0.278 | 0.131 | +| hGR | 5.416 / 5.668 / 5.849 | 11.033 / 11.534 / 11.916 | 7.660 / 5.591 / 7.574 | 3.680 / 4.048 / 3.386 | 0.278 | 0.114 | -Mean residual: GECKO 2 0.487, GECKO 4 0.127. +Mean residual: GECKO 2 0.487, GECKO 4 0.123. ## Median capacity usage per system (%) | system | CN4 | CN22 | CN38 | CN75 | hGR | |---|---|---|---|---|---| -| Amino acid metabolism | 1.7 / 1.3 | 4.6 / 2.0 | 2.1 / 3.1 | 3.2 / 5.5 | 5.6 / 7.8 | -| ETC | 100.0 / 40.6 | 96.0 / 66.2 | 100.0 / 100.0 | 70.6 / 100.0 | 99.5 / 100.0 | -| Glycolysis | 0.4 / 1.7 | 0.5 / 3.0 | 5.8 / 5.8 | 10.3 / 11.4 | 24.1 / 28.4 | +| Amino acid metabolism | 1.7 / 1.4 | 4.6 / 2.1 | 2.1 / 3.4 | 3.2 / 5.1 | 5.6 / 7.9 | +| ETC | 100.0 / 20.5 | 96.0 / 33.0 | 100.0 / 53.9 | 70.6 / 89.5 | 99.5 / 70.8 | +| Glycolysis | 0.4 / 1.7 | 0.5 / 3.1 | 5.8 / 5.7 | 10.3 / 11.5 | 24.1 / 30.2 | | Nitrogen metabolism | 10.3 / 0.9 | 1.7 / 7.1 | 2.3 / 0.1 | 4.8 / 0.1 | 18.0 / 0.1 | -| PP shunt | 5.6 / 11.0 | 11.7 / 0.8 | 20.5 / 0.0 | 20.6 / 0.2 | 41.7 / 1.8 | -| Ribosome | 28.8 / 26.3 | 33.9 / 29.0 | 33.7 / 47.3 | 33.6 / 57.3 | 66.4 / 74.0 | -| TCA cycle | 2.1 / 3.7 | 2.1 / 7.3 | 2.2 / 3.9 | 0.0 / 6.4 | 9.2 / 0.1 | -| THF cycle | 11.9 / 4.0 | 1.6 / 6.0 | 9.2 / 18.7 | 0.3 / 16.9 | 5.9 / 18.0 | +| PP shunt | 5.6 / 11.0 | 11.7 / 0.8 | 20.5 / 0.0 | 20.6 / 0.0 | 41.7 / 2.1 | +| Ribosome | 28.8 / 26.2 | 33.9 / 28.4 | 33.7 / 47.1 | 33.6 / 56.7 | 66.4 / 73.8 | +| TCA cycle | 2.1 / 1.1 | 2.1 / 7.7 | 2.2 / 16.7 | 0.0 / 46.4 | 9.2 / 2.2 | +| THF cycle | 11.9 / 4.9 | 1.6 / 9.2 | 9.2 / 13.0 | 0.3 / 12.8 | 5.9 / 17.0 | ## Sampled ATP and redox budget diff --git a/results/enzymeUsage/capUsage.tsv b/results/enzymeUsage/capUsage.tsv index 52655df..8511b37 100644 --- a/results/enzymeUsage/capUsage.tsv +++ b/results/enzymeUsage/capUsage.tsv @@ -1,172 +1,172 @@ protID geneID protName CN4 CN22 CN38 CN75 hGR GOterm -P00401 Q0045 COX1 40.644 66.173 100.0 100.0 100.0 ETC -P00163 Q0105 COB 58.216 93.386 100.0 100.0 100.0 ETC -P00410 Q0250 COX2 40.644 66.173 100.0 100.0 100.0 ETC -P00420 Q0275 COX3 40.644 66.173 100.0 100.0 100.0 ETC +P00401 Q0045 COX1 20.152 32.95 53.89 89.531 84.827 ETC +P00163 Q0105 COB 20.485 30.484 42.084 89.236 61.862 ETC +P00410 Q0250 COX2 20.152 32.95 53.89 89.531 84.827 ETC +P00420 Q0275 COX3 20.152 32.95 53.89 89.531 84.827 ETC P31373 YAL012W CYS3 3.146 4.126 6.236 6.375 12.635 Amino acid metabolism -P00549 YAL038W CDC19 3.016 3.072 4.835 9.763 30.059 Glycolysis -P39726 YAL044C GCV3 4.033 4.05 22.387 22.621 17.971 THF cycle -P07256 YBL045C COR1 58.216 93.386 100.0 100.0 100.0 ETC +P00549 YAL038W CDC19 3.017 3.237 4.817 9.973 30.16 Glycolysis +P39726 YAL044C GCV3 8.119 90.014 13.125 100.0 31.375 THF cycle +P07256 YBL045C COR1 20.485 30.484 42.084 89.236 61.862 ETC P07702 YBR115C LYS2 11.276 12.421 17.122 23.85 34.365 Amino acid metabolism -P20049 YBR166C TYR1 41.984 80.436 100.0 100.0 99.01 Amino acid metabolism -P12709 YBR196C PGI1 0.896 1.467 3.291 6.648 8.708 Glycolysis -P32473 YBR221C PDB1 39.552 4.138 9.677 14.488 28.361 Glycolysis +P20049 YBR166C TYR1 41.984 39.913 54.546 58.771 99.01 Amino acid metabolism +P12709 YBR196C PGI1 0.896 1.454 3.291 6.648 8.869 Glycolysis +P32473 YBR221C PDB1 100.0 100.0 100.0 100.0 100.0 Glycolysis P33734 YBR248C HIS7 11.653 12.9 22.139 23.828 44.428 Amino acid metabolism -P32449 YBR249C ARO4 0.736 1.297 2.982 5.632 3.109 Amino acid metabolism -P04173 YCL018W LEU2 0.364 0.439 0.637 5.618 1.548 Amino acid metabolism +P32449 YBR249C ARO4 0.736 0.944 2.283 2.476 3.109 Amino acid metabolism +P37292 YBR263W SHM1 0.0 0.0 0.0 0.0 0.001 THF cycle +P04173 YCL018W LEU2 0.364 0.439 0.637 5.222 1.548 Amino acid metabolism P00815 YCL030C HIS4 8.88 9.967 11.999 12.777 19.721 Amino acid metabolism P25379 YCL064C CHA1 0.0 0.0 0.0 0.0 0.0 Amino acid metabolism P08679 YCR005C CIT2 0.0 0.0 100.0 0.0 0.0 TCA cycle P25613 YCR010C ADY2 0.0 2.485 0.018 0.036 0.055 Nitrogen metabolism -P00560 YCR012W PGK1 0.405 0.516 1.331 2.727 4.941 Glycolysis +P00560 YCR012W PGK1 0.405 0.536 1.319 2.742 4.957 Glycolysis P16120 YCR053W THR4 0.023 0.021 0.04 0.046 0.084 Amino acid metabolism -P21954 YDL066W IDP1 14.417 0.0 0.0 0.0 0.0 TCA cycle -P07255 YDL067C COX9 40.644 66.173 100.0 100.0 100.0 ETC -P32419 YDL078C MDH3 0.0 0.0 0.001 0.001 0.0 TCA cycle +P21954 YDL066W IDP1 14.417 0.0 0.0 47.622 0.0 TCA cycle +P07255 YDL067C COX9 20.152 32.95 53.89 89.531 84.827 ETC +P32419 YDL078C MDH3 0.0 0.0 0.001 0.0 0.0 TCA cycle P48570 YDL182W LYS20 16.022 25.478 40.801 43.362 38.843 Amino acid metabolism P00912 YDR007W TRP1 0.0 0.0 0.0 0.0 0.0 Amino acid metabolism -P48015 YDR019C GCV1 8.118 5.001 32.787 30.145 34.818 THF cycle -P00942 YDR050C TPI1 0.021 0.03 0.064 0.127 0.235 Glycolysis -P08566 YDR127W ARO1 14.186 27.792 46.832 100.0 50.495 Amino acid metabolism -P19262 YDR148C KGD2 8.327 17.031 41.59 53.475 39.614 TCA cycle +P48015 YDR019C GCV1 8.119 90.014 13.125 100.0 31.375 THF cycle +P00942 YDR050C TPI1 0.021 0.032 0.062 0.126 0.236 Glycolysis +P08566 YDR127W ARO1 14.186 20.236 35.846 43.962 50.495 Amino acid metabolism +P19262 YDR148C KGD2 17.405 38.478 73.945 100.0 42.198 TCA cycle P13663 YDR158W HOM2 99.01 99.01 100.0 99.01 99.01 Amino acid metabolism -P37298 YDR178W SDH4 0.0 0.0 0.0 51.541 0.0 ETC P49367 YDR234W LYS4 89.664 100.0 100.0 100.0 100.0 Amino acid metabolism P32264 YDR300C PRO1 100.0 100.0 100.0 100.0 100.0 Amino acid metabolism P07285 YDR354W TRP4 43.615 100.0 100.0 100.0 100.0 Amino acid metabolism -Q12359 YDR384C ATO3 0.037 0.039 0.055 0.07 0.108 Nitrogen metabolism +Q12359 YDR384C ATO3 0.037 0.039 0.055 0.072 0.108 Nitrogen metabolism Q04409 YDR516C EMI2 19.855 55.462 100.0 100.0 100.0 Glycolysis -P00128 YDR529C QCR7 58.216 93.386 100.0 100.0 100.0 ETC -P08067 YEL024W RIP1 58.216 93.386 100.0 100.0 100.0 ETC -P32626 YEL038W UTR4 0.0 0.0 0.0 0.0 0.0 Amino acid metabolism +P00128 YDR529C QCR7 20.485 30.484 42.084 89.236 61.862 ETC +P08067 YEL024W RIP1 20.485 30.484 42.084 89.236 61.862 ETC +P32626 YEL038W UTR4 0.0 0.059 0.064 0.068 0.063 Amino acid metabolism P32263 YER023W PRO3 0.172 0.118 0.041 0.045 0.153 Amino acid metabolism P10869 YER052C HOM3 1.199 1.764 3.507 3.854 3.003 Amino acid metabolism P00498 YER055C HIS1 3.824 2.26 4.574 4.652 11.452 Amino acid metabolism -P28240 YER065C ICL1 0.0 0.0 0.0 100.0 0.0 TCA cycle +P28240 YER065C ICL1 0.0 40.834 0.0 100.0 0.0 TCA cycle Q01217 YER069W ARG5,6 24.521 21.182 45.264 53.426 100.0 Amino acid metabolism P00899 YER090W TRP2 0.457 0.498 0.914 1.035 1.538 Amino acid metabolism -P05694 YER091C MET6 11.9 15.395 18.814 22.528 16.42 Amino acid metabolism -P16387 YER178W PDA1 74.733 8.113 19.053 27.667 55.739 Glycolysis -P09624 YFL018C LPD1 44.564 19.835 58.939 65.684 50.059 THF cycle +P05694 YER091C MET6 11.887 15.395 18.814 22.528 16.42 Amino acid metabolism +P16387 YER178W PDA1 100.0 100.0 100.0 100.0 100.0 Glycolysis +P09624 YFL018C LPD1 44.568 100.0 100.0 100.0 100.0 THF cycle P38635 YFR025C HIS2 0.0 0.0 0.262 0.0 0.94 Amino acid metabolism -P39692 YFR030W MET10 1.229 1.042 1.582 1.852 2.262 Amino acid metabolism -P00127 YFR033C QCR6 58.216 93.386 100.0 100.0 100.0 ETC -P19955 YFR049W YMR31 30.315 56.769 100.0 100.0 93.476 Ribosome +P39692 YFR030W MET10 0.998 0.825 1.279 1.494 1.869 Amino acid metabolism +P00127 YFR033C QCR6 20.485 30.484 42.084 89.236 61.862 ETC +P19955 YFR049W YMR31 17.405 38.478 73.945 100.0 42.198 Ribosome P04806 YFR053C HXK1 0.0 0.0 12.744 54.66 17.883 Glycolysis -P07264 YGL009C LEU1 7.405 8.384 12.402 100.0 23.216 Amino acid metabolism +P07264 YGL009C LEU1 7.405 8.384 12.402 92.946 23.216 Amino acid metabolism P00931 YGL026C TRP5 0.342 0.505 0.526 0.604 1.019 Amino acid metabolism -P53128 YGL125W MET13 2.577 2.077 2.721 2.966 4.395 THF cycle -P28777 YGL148W ARO2 5.466 10.118 16.045 28.68 15.242 Amino acid metabolism -P50113 YGL154C LYS5 0.001 0.001 0.001 0.001 0.002 Amino acid metabolism -P04037 YGL187C COX4 33.069 0.0 11.401 71.542 64.127 ETC -P32799 YGL191W COX13 33.069 0.0 11.401 71.542 64.127 ETC +P53128 YGL125W MET13 2.574 2.077 2.721 2.966 4.395 THF cycle +P28777 YGL148W ARO2 5.466 7.367 12.282 12.608 15.242 Amino acid metabolism +P50113 YGL154C LYS5 11.276 12.421 17.122 23.85 34.365 Amino acid metabolism +P04037 YGL187C COX4 20.152 32.95 53.89 89.531 84.827 ETC +P32799 YGL191W COX13 20.152 32.95 53.89 89.531 84.827 ETC P53090 YGL202W ARO8 10.216 7.653 12.45 12.041 30.691 Amino acid metabolism P32582 YGR155W CYS4 0.452 0.374 0.385 0.403 1.635 Amino acid metabolism -P22289 YGR183C QCR9 58.216 93.386 100.0 100.0 100.0 ETC +P22289 YGR183C QCR9 20.485 30.484 42.084 89.236 61.862 ETC P07245 YGR204W ADE3 3.866 31.158 100.0 100.0 10.963 THF cycle -P42941 YGR208W SER2 1.941 2.666 12.962 18.334 7.878 Amino acid metabolism -P16861 YGR240C PFK1 5.845 9.754 19.408 38.344 40.116 Glycolysis -P53312 YGR244C LSC2 13.02 16.224 0.0 0.0 0.0 TCA cycle -P53315 YGR248W SOL4 100.0 0.0 0.0 0.0 0.011 PP shunt -P00924 YGR254W ENO1 1.475 2.991 5.77 10.912 42.825 Glycolysis +P42941 YGR208W SER2 1.94 2.666 12.962 18.335 7.878 Amino acid metabolism +P16861 YGR240C PFK1 4.959 7.948 15.965 30.412 34.2 Glycolysis +P53312 YGR244C LSC2 9.606 11.221 41.035 49.874 36.664 TCA cycle +P53315 YGR248W SOL4 100.0 0.0 0.0 0.0 0.003 PP shunt +P00924 YGR254W ENO1 1.475 3.113 5.712 10.977 42.966 Glycolysis P51601 YGR267C FOL2 5.957 5.952 9.37 8.774 22.953 THF cycle -P37299 YHR001W-A QCR10 58.216 93.386 100.0 100.0 100.0 ETC +P37299 YHR001W-A QCR10 20.485 30.484 42.084 89.236 61.862 ETC P04076 YHR018C ARG4 0.042 0.02 0.027 0.031 0.121 Amino acid metabolism P17423 YHR025W THR1 9.342 8.151 18.572 19.393 28.029 Amino acid metabolism P07275 YHR037W PUT2 100.0 100.0 0.0 0.0 0.0 Nitrogen metabolism -P00427 YHR051W COX6 33.069 0.0 11.401 71.542 64.127 ETC +P00427 YHR051W COX6 20.152 32.95 53.89 89.531 84.827 ETC P38840 YHR137W ARO9 3.636 8.11 0.0 0.0 0.001 Amino acid metabolism -P38858 YHR163W SOL3 100.0 14.584 0.0 0.0 100.0 PP shunt -P38720 YHR183W GND1 8.11 0.537 0.0 0.0 5.315 PP shunt -P38891 YHR208W BAT1 0.098 0.115 0.181 1.636 0.691 Amino acid metabolism +P38858 YHR163W SOL3 100.0 23.983 0.0 0.0 100.0 PP shunt +P38720 YHR183W GND1 8.108 0.884 0.0 0.0 2.322 PP shunt +P38891 YHR208W BAT1 0.098 0.115 0.181 1.534 0.691 Amino acid metabolism P40545 YIL020C HIS6 15.874 14.555 22.322 24.213 70.569 Amino acid metabolism -P40510 YIL074C SER33 0.16 0.277 1.06 1.714 0.485 Amino acid metabolism +P40510 YIL074C SER33 0.16 0.252 1.06 1.714 0.486 Amino acid metabolism P40495 YIL094C LYS12 4.401 6.765 11.92 13.243 17.844 Amino acid metabolism P07172 YIL116W HIS5 0.025 0.02 0.029 0.03 0.117 Amino acid metabolism -P20967 YIL125W KGD1 17.403 42.364 100.0 100.0 46.829 TCA cycle +P20967 YIL125W KGD1 17.405 38.478 73.945 100.0 42.198 TCA cycle P38998 YIR034C LYS1 0.002 0.002 0.002 0.002 0.006 Amino acid metabolism -P47052 YJL045W YJL045W 23.547 50.183 86.591 100.0 55.055 ETC -P00360 YJL052W TDH1 15.681 24.749 100.0 100.0 100.0 Glycolysis +P47052 YJL045W YJL045W 58.419 87.202 100.0 100.0 70.829 ETC +P00360 YJL052W TDH1 15.681 25.707 100.0 100.0 100.0 Glycolysis P05150 YJL088W ARG3 0.013 0.011 0.015 0.019 0.045 Amino acid metabolism -P46969 YJL121C RPE1 13.89 2.624 5.711 7.088 1.711 PP shunt -P07259 YJL130C URA2 0.125 0.108 0.162 0.291 0.38 Amino acid metabolism -P08525 YJL166W QCR8 58.216 93.386 100.0 100.0 100.0 ETC +P46969 YJL121C RPE1 13.885 1.493 5.205 5.044 6.366 PP shunt +P07259 YJL130C URA2 0.125 0.108 0.162 0.312 0.38 Amino acid metabolism +P08525 YJL166W QCR8 20.485 30.484 42.084 89.236 61.862 ETC P39533 YJL200C ACO2 0.0 38.369 100.0 100.0 100.0 TCA cycle -P00358 YJR009C TDH2 0.0 0.0 0.016 0.24 0.5 Glycolysis -P08536 YJR010W MET3 0.825 1.094 1.478 1.718 2.78 Amino acid metabolism -P39522 YJR016C ILV3 6.474 11.101 13.061 32.08 22.13 Amino acid metabolism +P00358 YJR009C TDH2 0.0 0.0 0.014 0.242 0.502 Glycolysis +P08536 YJR010W MET3 0.825 1.094 1.478 1.701 2.78 Amino acid metabolism +P39522 YJR016C ILV3 6.474 8.709 13.061 30.836 22.13 Amino acid metabolism P47095 YJR024C MDE1 0.312 30.708 34.076 34.637 70.436 Amino acid metabolism -P47169 YJR137C MET5 0.84 0.682 1.074 1.274 1.593 Amino acid metabolism +P47169 YJR137C MET5 0.998 0.825 1.279 1.494 1.869 Amino acid metabolism P31116 YJR139C HOM6 1.96 1.689 2.421 2.681 7.708 Amino acid metabolism -P47176 YJR148W BAT2 0.873 0.398 1.244 6.47 19.483 Amino acid metabolism -Q02196 YKL001C MET14 5.017 8.299 11.776 11.436 19.032 Amino acid metabolism -P14540 YKL060C FBA1 1.685 2.066 5.697 11.404 17.645 Glycolysis -P17505 YKL085W MDH1 7.133 13.07 25.767 43.043 22.409 TCA cycle -P33421 YKL141W SDH3 23.547 50.183 86.591 100.0 55.055 ETC -Q00711 YKL148C SDH1 0.0 0.0 0.0 51.541 0.0 ETC -P00950 YKL152C GPM1 0.603 0.649 1.53 3.404 8.641 Glycolysis +P47176 YJR148W BAT2 0.873 0.398 1.244 6.121 19.483 Amino acid metabolism +Q02196 YKL001C MET14 5.017 8.299 11.776 11.323 19.032 Amino acid metabolism +P14540 YKL060C FBA1 1.685 2.066 5.707 11.455 17.758 Glycolysis +P17505 YKL085W MDH1 7.134 12.979 25.824 43.952 20.558 TCA cycle +P33421 YKL141W SDH3 58.419 87.202 100.0 100.0 70.829 ETC +P00950 YKL152C GPM1 0.603 0.676 1.515 3.424 8.669 Glycolysis P00937 YKL211C TRP3 6.372 9.884 11.348 13.076 25.062 Amino acid metabolism Q02046 YKR080W MTD1 92.9 100.0 100.0 100.0 100.0 THF cycle -P21801 YLL041C SDH2 23.547 50.183 86.591 100.0 55.055 ETC +P21801 YLL041C SDH2 58.419 87.202 100.0 100.0 70.829 ETC Q07938 YLR017W MEU1 0.938 100.0 100.0 100.0 100.0 Nitrogen metabolism -P23542 YLR027C AAT2 0.4 0.521 0.624 0.74 1.489 Amino acid metabolism -Q01519 YLR038C COX12 33.069 0.0 11.401 71.542 64.127 ETC +P23542 YLR027C AAT2 0.4 0.521 0.624 0.741 1.489 Amino acid metabolism +Q01519 YLR038C COX12 20.152 32.95 53.89 89.531 84.827 ETC P37291 YLR058C SHM2 0.067 0.138 0.828 1.212 0.185 THF cycle P09368 YLR142W PUT1 0.003 100.0 0.0 0.0 0.0 Nitrogen metabolism -Q06236 YLR164W SHH4 23.547 50.183 86.591 100.0 55.055 ETC -P41939 YLR174W IDP2 5.142 18.054 100.0 100.0 76.347 TCA cycle +Q06236 YLR164W SHH4 58.419 87.202 100.0 100.0 70.829 ETC +P41939 YLR174W IDP2 5.143 16.446 100.0 100.0 70.027 TCA cycle P06106 YLR303W MET17 0.02 0.031 0.044 0.049 0.084 Amino acid metabolism -P19414 YLR304C ACO1 16.454 19.089 25.664 44.226 33.688 TCA cycle -P15019 YLR354C TAL1 1.455 0.107 0.065 0.406 1.35 PP shunt -P06168 YLR355C ILV5 1.377 2.157 3.925 15.122 6.752 Amino acid metabolism -P04039 YLR395C COX8 33.069 0.0 11.401 71.542 64.127 ETC +P19414 YLR304C ACO1 16.456 18.957 25.72 45.16 30.899 TCA cycle +P15019 YLR354C TAL1 1.455 0.107 0.021 0.024 0.565 PP shunt +P06168 YLR355C ILV5 1.377 1.944 3.925 14.264 6.752 Amino acid metabolism +P04039 YLR395C COX8 20.152 32.95 53.89 89.531 84.827 ETC P07991 YLR438W CAR2 0.0 0.0 8.632 10.387 56.974 Amino acid metabolism Q03677 YMR009W ADI1 0.0 0.059 0.064 0.068 0.063 Amino acid metabolism Q04728 YMR062C ARG7 8.641 8.621 26.817 30.527 79.183 Amino acid metabolism -P07342 YMR108W ILV2 0.654 0.883 1.308 5.302 2.172 Amino acid metabolism +P07342 YMR108W ILV2 0.654 0.83 1.308 4.987 2.172 Amino acid metabolism Q12676 YMR113W FOL3 0.0 0.0 0.14 0.166 0.0 THF cycle -P54114 YMR169C ALD3 0.005 0.425 0.0 0.0 0.0 Amino acid metabolism -P49095 YMR189W GCV2 24.398 16.165 100.0 100.0 77.885 THF cycle -P16862 YMR205C PFK2 4.307 6.706 13.518 25.015 29.475 Glycolysis -P10174 YMR256C COX7 33.069 0.0 11.401 71.542 64.127 ETC +P54114 YMR169C ALD3 0.005 0.422 0.0 0.0 0.0 Amino acid metabolism +P49095 YMR189W GCV2 8.119 90.014 13.125 100.0 31.375 THF cycle +P16862 YMR205C PFK2 4.959 7.948 15.965 30.412 34.2 Glycolysis +P10174 YMR256C COX7 20.152 32.95 53.89 89.531 84.827 ETC Q03266 YMR289W ABZ2 0.0 0.0 1.271 1.639 0.0 THF cycle -P53982 YNL009W IDP3 0.0 0.011 0.0 0.0 0.0 TCA cycle -P00424 YNL052W COX5A 33.069 0.0 11.401 71.542 64.127 ETC +P53982 YNL009W IDP3 0.0 0.0 0.0 0.558 0.0 TCA cycle +P28834 YNL037C IDH1 0.0 0.0 4.755 71.434 0.0 TCA cycle +P00424 YNL052W COX5A 20.152 32.95 53.89 89.531 84.827 ETC P06208 YNL104C LEU4 0.005 0.005 0.004 0.0 0.011 Amino acid metabolism -P30952 YNL117W MLS1 0.0 0.0 0.0 0.002 0.0 TCA cycle -P11412 YNL241C ZWF1 1.14 0.072 0.0 0.0 0.782 PP shunt +P30952 YNL117W MLS1 0.0 0.009 0.0 0.002 0.0 TCA cycle +P11412 YNL241C ZWF1 1.139 0.118 0.0 0.0 0.342 PP shunt P53848 YNL256W FOL1 0.0 8.782 18.668 0.0 40.128 THF cycle P08465 YNL277W MET2 15.112 17.52 24.193 31.116 50.673 Amino acid metabolism P32452 YNL316C PHA2 1.362 1.883 2.378 3.508 8.011 Amino acid metabolism -P00890 YNR001C CIT1 5.597 11.535 27.188 41.279 13.534 TCA cycle +P00890 YNR001C CIT1 5.598 11.456 27.248 42.15 12.413 TCA cycle P37254 YNR033W ABZ1 81.805 86.542 99.01 99.01 0.003 THF cycle P38999 YNR050C LYS9 0.547 0.663 1.302 1.378 1.927 Amino acid metabolism P22768 YOL058W ARG1 31.499 20.675 20.373 25.001 99.01 Amino acid metabolism -P32179 YOL064C MET22 11.321 9.717 30.703 35.564 37.936 Amino acid metabolism -P22133 YOL126C MDH2 0.003 0.006 0.021 0.076 0.096 TCA cycle +P32179 YOL064C MET22 11.321 9.717 30.703 35.392 38.422 Amino acid metabolism +P22133 YOL126C MDH2 0.003 0.0 0.024 0.099 0.096 TCA cycle P18544 YOL140W ARG8 50.038 65.748 100.0 100.0 100.0 Amino acid metabolism -P07143 YOR065W CYT1 58.216 93.386 100.0 100.0 100.0 ETC +P07143 YOR065W CYT1 20.485 30.484 42.084 89.236 61.862 ETC P06785 YOR074C CDC21 0.196 0.188 0.303 0.281 0.709 THF cycle Q12189 YOR095C RKI1 100.0 100.0 100.0 100.0 100.0 PP shunt -Q12166 YOR108W LEU9 0.0 0.0 0.001 0.032 100.0 Amino acid metabolism +Q12166 YOR108W LEU9 0.0 0.0 0.001 0.03 100.0 Amino acid metabolism Q12375 YOR130C ORT1 0.003 0.003 0.004 0.004 0.012 Amino acid metabolism -P53598 YOR142W LSC1 7.609 10.335 0.0 0.0 0.0 TCA cycle +P28241 YOR136W IDH2 0.0 0.0 4.755 71.434 0.0 TCA cycle +P53598 YOR142W LSC1 9.606 11.221 41.035 49.874 36.664 TCA cycle P33330 YOR184W SER1 100.0 100.0 100.0 100.0 100.0 Amino acid metabolism P06633 YOR202W HIS3 0.101 0.112 0.191 0.183 0.457 Amino acid metabolism P07807 YOR236W DFR1 0.0 0.0 0.0 0.0 0.0 Amino acid metabolism P54885 YOR323C PRO2 12.653 12.745 1.428 1.431 3.138 Amino acid metabolism -P07262 YOR375C GDH1 17.557 7.083 16.2 23.563 44.073 Nitrogen metabolism -P46151 YPL023C MET12 11.517 9.629 12.914 16.874 37.237 THF cycle -P19516 YPL132W COX11 0.0 66.173 100.0 100.0 100.0 Ribosome -P08417 YPL262W FUM1 2.176 4.265 7.802 12.664 4.865 TCA cycle -P43635 YPR001W CIT3 0.0 0.0 0.0 0.0 0.0 TCA cycle -P32288 YPR035W GLN1 1.581 0.242 0.442 1.163 3.12 Nitrogen metabolism -P32178 YPR060C ARO7 8.119 8.542 9.872 14.458 28.155 Amino acid metabolism -P23254 YPR074C TKL1 4.21 1.121 1.956 3.404 1.972 PP shunt +P07262 YOR375C GDH1 17.555 7.083 16.2 23.564 44.073 Nitrogen metabolism +P46151 YPL023C MET12 11.505 9.629 12.914 16.874 37.237 THF cycle +P08417 YPL262W FUM1 2.176 4.226 7.766 12.601 4.413 TCA cycle +P43635 YPR001W CIT3 0.0 0.005 0.0 0.0 0.0 TCA cycle +P32288 YPR035W GLN1 1.581 0.242 0.442 1.275 3.12 Nitrogen metabolism +P32178 YPR060C ARO7 8.119 5.969 7.292 5.85 28.155 Amino acid metabolism +P23254 YPR074C TKL1 4.208 0.816 1.573 1.569 1.972 PP shunt Q06489 YPR118W MRI1 0.025 3.146 3.266 3.243 4.755 Amino acid metabolism P49089 YPR145W ASN1 11.508 5.376 12.497 14.31 38.819 Amino acid metabolism -P18408 YPR167C MET16 99.01 99.01 100.0 100.0 99.01 Amino acid metabolism -P07257 YPR191W QCR2 58.216 93.386 100.0 100.0 100.0 ETC +P18408 YPR167C MET16 99.01 99.01 100.0 99.01 99.01 Amino acid metabolism +P07257 YPR191W QCR2 20.485 30.484 42.084 89.236 61.862 ETC P14126 YOR063W YOR063W 15.017 19.305 29.594 32.518 43.345 Ribosome P26783 YJR123W YJR123W 28.967 32.368 56.905 58.776 80.915 Ribosome P05755 YBR189W YBR189W 26.818 29.625 43.55 51.823 70.409 Ribosome diff --git a/results/enzymeUsage/enzymeUsages.tsv b/results/enzymeUsage/enzymeUsages.tsv index 019ee50..a0bc230 100644 --- a/results/enzymeUsage/enzymeUsages.tsv +++ b/results/enzymeUsage/enzymeUsages.tsv @@ -1,47 +1,47 @@ protID geneID protName capUse_CN4 capUse_CN22 capUse_CN38 capUse_CN75 capUse_hGR absUse_CN4 absUse_CN22 absUse_CN38 absUse_CN75 absUse_hGR UB_CN4 UB_CN22 UB_CN38 UB_CN75 UB_hGR -P00401 Q0045 COX1 0.4064403832321702 0.6617329222160458 0.999999999999984 1.0000000000000389 1.000000000000396 0.1269765665949233 0.17823988545995756 0.2305256572308094 0.2835792387754409 0.3799707799916717 0.31241129531754896 0.2693532080330211 0.23052565723081309 0.2835792387754299 0.3799707799915213 -P00856 Q0080 ATP8 1.0 0.9999999999999998 0.9999999999999999 1.0 1.0000000000003733 0.1272455119295709 0.1621107082817352 0.22303518852503937 0.2751175256100435 0.37317999216086234 0.1272455119295709 0.16211070828173524 0.2230351885250394 0.2751175256100435 0.37317999216072306 -P00854 Q0085 ATP6 1.0000000000000002 1.0 1.0 1.0 1.0000000000003733 0.6359871438747138 0.8102472518533516 1.1147545432652217 1.3750678250990473 1.8651948800908507 0.6359871438747137 0.8102472518533516 1.1147545432652217 1.3750678250990473 1.8651948800901545 -P00163 Q0105 COB 0.5821562574079977 0.9338617272706926 0.9999999999999836 1.0000000000000397 1.0000000000003961 0.2233392718436343 0.3099806742434078 0.40439738410706205 0.4979382250344143 0.6683311700805642 0.3836414519325685 0.3319342309373341 0.4043973841070687 0.49793822503439455 0.6683311700802995 -P61829 Q0130 OLI1 1.0 1.0 1.0 1.0 1.000000000000373 1.695805439817143 2.1604551452387213 2.9723978491339413 3.6665009982966805 4.973382959766628 1.695805439817143 2.1604551452387213 2.9723978491339413 3.6665009982966805 4.9733829597647725 -P00410 Q0250 COX2 0.4064403832321701 0.6617329222160458 0.999999999999984 1.0000000000000384 1.0000000000003957 0.06169154695597084 0.08659782319015284 0.11200085802429557 0.13777693312864414 0.1846087498217981 0.15178498372965785 0.13086521810060397 0.11200085802429736 0.13777693312863884 0.18460874982172504 -P00420 Q0275 COX3 0.4064403832321702 0.6617329222160458 0.999999999999984 1.0000000000000384 1.000000000000396 0.0655636001534384 0.09203311205422482 0.11903056147364491 0.14642446493456213 0.1961956678891655 0.16131172702882388 0.1390789379890901 0.11903056147364681 0.1464244649345565 0.19619566788908782 -P31373 YAL012W CYS3 0.03146060221216871 0.04126036610127187 0.06236310437184269 0.06374952528877574 0.1263477086755265 0.02464674273575084 0.024646742735751726 0.02464674273574815 0.02464674273601177 0.07147555393367713 0.7834161142095899 0.5973466807167273 0.39521353184714614 0.3866184512647858 0.5657051851825305 +P00401 Q0045 COX1 0.20151667323204323 0.32950143624461603 0.5389014434584413 0.8953092692728255 0.8482724115955426 0.053909127735339714 0.07634819240526798 0.0982814425689631 0.12233224345214028 0.14935474369963186 0.26751695961784866 0.2317082234160231 0.18237368587887687 0.13663685572193296 0.17606931648137156 +P00856 Q0080 ATP8 0.18606678454578027 0.2792293484145761 0.5299665414308692 0.8820433979562665 0.5896040184072172 0.00670041957038675 0.009116909049173689 0.011836933010611072 0.01524191094836809 0.018207066769735217 0.03601083120097754 0.03265025363894656 0.022335245879206368 0.017280227915864765 0.03088016058459134 +P00854 Q0085 ATP6 0.18606678454578027 0.27922934841457603 0.5299665414308693 0.8820433979562665 0.5896040184072173 0.03348943817909379 0.045567319893834626 0.05916230052830155 0.07618075690253574 0.0910009336881699 0.17998611767730086 0.16318957929228892 0.11163402951546308 0.08636849057432992 0.15434245840793945 +P00163 Q0105 COB 0.20484506483564066 0.30483730085091143 0.420838398545406 0.892359746616224 0.6186205673623894 0.04468146370537565 0.06327961759415994 0.08085499277398582 0.10102926078613235 0.12378958518125115 0.21812321298160753 0.20758489009554798 0.1921283634132593 0.11321584279123907 0.2001058350016593 +P61829 Q0130 OLI1 0.18606678454578027 0.27922934841457614 0.5299665414308693 0.8820433979562665 0.5896040184072173 0.08929672869569014 0.12150136948220314 0.15775122505896827 0.20312948651389218 0.24264622306144895 0.47991762158774437 0.4351310855111411 0.29766261212085576 0.23029420886155053 0.4115409927444937 +P00410 Q0250 COX2 0.20151667323204325 0.32950143624461603 0.5389014434584413 0.8953092692728255 0.8482724115955428 0.02619174210033419 0.03709375850269211 0.04775002499859806 0.05943510321264824 0.07256398114336175 0.1299730770672996 0.11257540763844913 0.0886062295401523 0.06638499706466987 0.08554325255830711 +P00420 Q0275 COX3 0.20151667323204325 0.3295014362446161 0.5389014434584414 0.8953092692728254 0.8482724115955428 0.027835659683065984 0.03942193818537937 0.050747042355075336 0.06316553133111634 0.07711843972109296 0.1381308019660173 0.11964117253835949 0.09416757548356579 0.07055163338409273 0.09091235158295248 +P31373 YAL012W CYS3 0.03146060221263166 0.04126036610126885 0.062363104371851566 0.06374952528801893 0.12634770867551703 0.02464674273611352 0.02464674273574992 0.024646742735751657 0.024646742735719176 0.07147555393367179 0.7834161142095899 0.5973466807167273 0.39521353184714614 0.3866184512647858 0.5657051851825305 P31381 YAL022C FUN26 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P31382 YAL023C PMT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.05156212525023815 0.06565030089067744 0.04855487759124904 0.04072519078238384 0.06262241516608258 +P31382 YAL023C PMT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.08922848362019764 0.1033909548243435 0.0743040693091965 0.06866968922231478 0.09501132644573686 P39524 YAL026C DRS2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P39730 YAL035W FUN12 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2819624501087919 0.24997662050639255 0.1567941805063925 0.13219980651363974 0.3137835784688681 -P00549 YAL038W CDC19 0.03016474948829044 0.03072463049708433 0.04835447902081869 0.09762539298098459 0.3005859624312334 0.10286249996433215 0.1490248106924185 0.2075949324377524 0.36078941974159306 0.6219099192339157 3.410023345437098 4.850336953818223 4.293189310309264 3.695651394836048 2.068991892381512 +P00549 YAL038W CDC19 0.03016661639981684 0.03236637768499047 0.04816647472519394 0.099727530615665 0.3016005284742728 0.10286886617622104 0.1569878377467468 0.20678779440548398 0.36855818762333703 0.6240090481512498 3.410023345437098 4.850336953818223 4.293189310309264 3.695651394836048 2.068991892381512 P06182 YAL039C CYC3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.006656315536037322 0.005413968146562386 0.003254333216568742 0.0028215378530860543 0.004355071773269715 -P39726 YAL044C GCV3 0.04032787270896365 0.0405017838846142 0.22386665197487357 0.2262098586904649 0.1797143326970893 0.0043405541169897624 0.006504124285787124 0.020603749016881705 0.01669461411891042 0.012222920115944443 0.10763161618552199 0.16058858800680895 0.09203581165449437 0.07380144356022324 0.06801305122695096 -Q01574 YAL054C ACS1 0.0 0.3012411037276521 1.0 1.0 0.9999999999999104 0.0 0.37887357864522986 0.024831452038058876 0.01470659530564137 0.06493959567367426 3.9479293849631776 1.2577087719999998 0.024831452038058876 0.01470659530564137 0.06493959567368007 +P39726 YAL044C GCV3 0.08119253502199797 0.9001382728239322 0.13124597964078502 1.0000000000000002 0.3137471920583541 0.0043411201614605745 0.117080127880389 0.008247779772579067 0.05538177140555007 0.011014255787667904 0.053466986346520765 0.13006904762874133 0.06284215177602323 0.05538177140555006 0.03510551191042804 +Q01574 YAL054C ACS1 0.0 0.05168838558570535 1.0 1.0 1.0 0.0 0.06500893596165996 0.024831452038058876 0.01470659530564137 0.06493959567368007 3.9479293849631776 1.2577087719999998 0.024831452038058876 0.01470659530564137 0.06493959567368007 P39714 YAL060W BDH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6171568196486232 0.2575436729063476 0.1223909085153313 0.09766798192627685 0.2817554984824013 P39713 YAL061W BDH2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P39708 YAL062W GDH3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.003953239089183651 0.02373830139284502 0.003800064434828841 0.0020657477809705588 1000.0 -P27616 YAR015W ADE1 0.007207110137582067 0.007545567381525318 0.01238369805994265 0.01258748835598088 0.03652659500720776 0.0018181943009280086 0.0018181943009278909 0.0018181943009268286 0.0018181943009346112 0.005272763472687383 0.2522778570354968 0.2409619063742755 0.14682159498123687 0.14444456666136304 0.14435409245364683 +P27616 YAR015W ADE1 0.007207110137619698 0.007545567381523617 0.012383698059944371 0.012587488355928865 0.03652659500721189 0.0018181943009375019 0.001818194300927481 0.0018181943009270812 0.001818194300927098 0.0052727634726879805 0.2522778570354968 0.2409619063742755 0.14682159498123687 0.14444456666136304 0.14435409245364683 P80235 YAR035W YAT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.19271306624894552 0.02451795121318007 1000.0 1000.0 0.02762413441158763 P35842 YAR071W PHO11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P32784 YBL011W SCT1 0.0006933781065685536 0.0006994642860962691 0.0007543571716433327 0.0007543571716042172 0.0021876730290176535 0.6933781065685536 0.6994642860962691 0.7543571716433327 0.7543571716042171 2.1876730290176534 1000.0 1000.0 1000.0 1000.0 1000.0 +P32784 YBL011W SCT1 0.0006839204828687844 0.0006994642860962832 0.0007543571716042186 0.0007543571716042176 0.002187673029017655 0.6839204828687844 0.6994642860962832 0.7543571716042186 0.7543571716042176 2.1876730290176547 1000.0 1000.0 1000.0 1000.0 1000.0 P32785 YBL013W FMT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P32316 YBL015W ACH1 0.0 1.0 0.9999999999996196 0.9999999999999999 1.0000000000006577 0.0 0.40286238046871475 2.893535893006364 3.030329791907006 4.298455689530546 0.8005095219529469 0.40286238046871475 2.8935358930074644 3.0303297919070062 4.298455689527719 +P32316 YBL015W ACH1 0.0 1.0 1.0 1.0 1.0 0.0 0.40286238046871475 0.2414838869403105 0.14602662293185484 0.8125186921989169 0.8005095219529469 0.40286238046871475 0.2414838869403105 0.14602662293185484 0.8125186921989169 P18239 YBL030C PET9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P38066 YBL033C RIB1 0.00032420617319971255 0.00038876291096845525 0.0007858770522567211 2.464763303253681e-09 0.0011911764419816964 2.464763303253681e-06 2.464763303253681e-06 2.464763303253681e-06 2.464763303253681e-06 7.147813579435674e-06 0.007602456421258132 0.006340016585207829 0.003136321764550673 1000.0 0.00600063376634971 +P38066 YBL033C RIB1 0.00032420617319971255 0.00038876291096844994 0.0007858770522567211 2.464763303253681e-09 0.0011911764419816964 2.464763303253681e-06 2.464763303253647e-06 2.464763303253681e-06 2.464763303253681e-06 7.147813579435674e-06 0.007602456421258132 0.006340016585207829 0.003136321764550673 1000.0 0.00600063376634971 P28274 YBL039C URA7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.07779217940840107 0.043723252799999994 0.025331487128492456 0.02116527432497104 0.08423141700831217 P38196 YBL042C FUI1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P07256 YBL045C COR1 0.5821562574079977 0.9338617272706929 0.9999999999999837 1.0000000000000397 1.0000000000003961 0.25696089761228846 0.3566453478536259 0.46527560493241515 0.5728981392484095 0.7689421387851975 0.441395062480966 0.3819038059263427 0.46527560493242276 0.5728981392483867 0.7689421387848929 +P07256 YBL045C COR1 0.20484506483564063 0.3048373008509114 0.420838398545406 0.8923597466162237 0.6186205673623894 0.051407837616676014 0.07280576856604969 0.09302695109610958 0.11623826531899063 0.14242494237868522 0.25095961017134377 0.2388348419396918 0.22105148061025262 0.13025942257005582 0.23022988547881948 P34227 YBL064C PRX1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.08422429918986302 0.10524121866138432 0.08350846342819905 0.061813338340314966 0.03438126134229327 P38063 YBL068W PRS4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.042413550446720294 0.03199940000622554 0.021754304961886687 0.018415928285491698 0.024412833999999994 P09436 YBL076C ILS1 0.03589337925754695 0.040851905194167815 0.06796496101986502 0.07764715412956047 0.09608561324013404 0.01128077029308413 0.01128077029308413 0.01128077029308413 0.01128077029308413 0.03271423384994398 0.31428554587019647 0.2761381688189813 0.1659792064 0.14528246939045913 0.3404696368871126 P33893 YBL080C PET112 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38174 YBL091C MAP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06744411729616957 0.07106005273598365 0.04976379648698022 0.04964151954968363 0.04161073093493075 -P38169 YBL098W BNA4 0.1797782243910308 0.3250231780239971 0.5544703624154461 0.7825504565883937 0.6516204746876538 0.004354734929347658 0.0043547349293429185 0.004354734929335698 0.004355595832489063 0.012628731295055682 0.024222816440081143 0.013398228876530768 0.0078538642 0.005565897758820198 0.01938050105179569 -P07251 YBL099W ATP1 1.0 1.0 1.0 1.0 1.0000000000003733 3.84280571788129 4.8957322523063915 6.7356473698430985 8.308530371497815 11.27001012395937 3.84280571788129 4.8957322523063915 6.7356473698430985 8.308530371497815 11.270010123955164 +P38169 YBL098W BNA4 0.17977822439053154 0.32502317802389363 0.5544703624162574 0.7823957819676276 0.6516204746890424 0.004354734929335564 0.004354734929341532 0.004354734929342069 0.0043547349293639945 0.012628731295082593 0.024222816440081143 0.013398228876530768 0.0078538642 0.005565897758820198 0.01938050105179569 +P07251 YBL099W ATP1 0.18606678454578027 0.2792293484145761 0.5299665414308693 0.8820433979562665 0.5896040184072174 0.20235221067394024 0.27533002690860786 0.35747456366500885 0.46030466344655985 0.5498521655310762 1.0875246281485187 0.9860354166633701 0.6745228910109207 0.5218616958225707 0.9325787280359306 P35172 YBR001C NTH2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.006106170916836198 1000.0 1000.0 1000.0 P35196 YBR002C RER2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P18900 YBR003W COQ1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0018518267442154124 0.00118659456 0.000816892045720525 0.0006511301255026202 0.0031384729241733375 P38211 YBR004C GPI18 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P38067 YBR006W UGA2 0.0 0.01820495235598909 0.0 0.0 0.0 0.0 0.0015079031745331318 0.0 0.0 0.0 0.05010838918686469 0.08282928430939067 0.061636802108807 0.05308134162204059 0.021924953801499558 -P00817 YBR011C IPP1 0.014025551960796133 0.07796381886359253 0.055997387263157714 0.07823357540202758 0.13725853173241517 0.01348868110361973 0.07859099823457247 0.03701244418537916 0.04706186364521601 0.09757993353329282 0.9617219444427535 1.0080444926906065 0.6609673414125646 0.6015558333282606 0.7109207151037024 +P38067 YBR006W UGA2 0.0 0.01820495235598909 0.0 0.0028480837219988435 0.016394175234756485 0.0 0.0015079031745331318 0.0 0.0001511801050155935 0.00035944153463572415 0.05010838918686469 0.08282928430939067 0.061636802108807 0.05308134162204059 0.021924953801499558 +P00817 YBR011C IPP1 0.014016284682335612 0.04151128132072906 0.051711948395163736 0.07940058243330401 0.15666814861306202 0.013479768558558987 0.04184521851989137 0.03417990905001511 0.047763883532415445 0.11137863224597118 0.9617219444427535 1.0080444926906065 0.6609673414125646 0.6015558333282606 0.7109207151037024 P08431 YBR018C GAL7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P04397 YBR019C GAL10 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P04385 YBR020W GAL1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 @@ -49,21 +49,21 @@ P05316 YBR021W FUR4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 P38218 YBR022W POA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P29465 YBR023C CHS3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38071 YBR026C ETR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2563228982048048 0.3592412837695561 0.16581794418491896 0.11913083833854826 0.04386074796107561 -P38221 YBR029C CDS1 0.024595719649042554 0.016338964688189905 0.032560258392355 0.03828638667158489 0.05887515096396152 0.00990160595636581 0.009809808375477866 0.009874399303521703 0.009874399303517065 0.02863602210371595 0.40257435430441874 0.6003935110141079 0.30326538519854523 0.257908885166371 0.48638554016183405 +P38221 YBR029C CDS1 0.02446878858498619 0.016338964688190103 0.032560258392339704 0.03828638667165159 0.058875150963956596 0.009850506765212147 0.009809808375477983 0.009874399303517065 0.009874399303534266 0.028636022103713552 0.40257435430441874 0.6003935110141079 0.30326538519854523 0.257908885166371 0.48638554016183405 P38074 YBR034C HMT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03035733556206722 0.01416581164267403 0.008793175306244029 0.0072298562869867475 0.021134455455373076 -P38075 YBR035C PDX3 0.0 0.6424895159994444 0.49831122761865393 0.4706760913040479 0.0 0.0 0.07340047937193524 0.03947178624475082 0.034415545541658855 0.0 0.13096582682136915 0.11424385541568699 0.07921111156451338 0.07311938332433177 0.07294739765328302 +P38075 YBR035C PDX3 0.0 0.0 0.49831122761865393 0.0 0.0 0.0 0.0 0.03947178624475082 0.0 0.0 0.13096582682136915 0.11424385541568699 0.07921111156451338 0.07311938332433177 0.07294739765328302 P35206 YBR036C CSG2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P14180 YBR038W CHS2 3.1141872250537375e-05 3.1141872250537375e-05 3.1141872250537375e-05 3.1141872250537375e-05 9.031142952655836e-05 0.031141872250537373 0.031141872250537373 0.031141872250537373 0.031141872250537373 0.09031142952655836 1000.0 1000.0 1000.0 1000.0 1000.0 -P38077 YBR039W ATP3 1.0 1.0 1.0 1.0 1.0000000000003733 0.75077474755972 0.9564865922682732 1.3159535831370024 1.6232501068757477 2.201838871645102 0.75077474755972 0.9564865922682732 1.3159535831370024 1.6232501068757477 2.20183887164428 -P38225 YBR041W FAT1 0.0 8.451300966099682e-09 1.537874968792357e-06 0.0 0.0 0.0 8.451300966099682e-06 0.001537874968792357 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P38077 YBR039W ATP3 0.18606678454578027 0.27922934841457603 0.5299665414308693 0.8820433979562665 0.5896040184072173 0.03953385652050073 0.05379164251943755 0.06984034452894211 0.08993041617784135 0.10742544668622028 0.21247132644877698 0.19264322616823315 0.13178255431065233 0.10195690641323782 0.18219931230527261 +P38225 YBR041W FAT1 0.0 0.0 1.5597235545241905e-06 4.125812370994774e-09 0.0 0.0 0.0 0.0015597235545241905 4.125812370994774e-06 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38226 YBR042C CST26 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38230 YBR046C ZTA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.05752637865440272 0.05826279203031916 0.024117313418042984 0.02146772821142646 0.010732918669999997 -Q3E790 YBR058C-A TSC3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q3E790 YBR058C-A TSC3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0022938955312279395 0.002317734029077169 0.001689267127689421 0.001659242071168403 0.002071008905834984 P38084 YBR068C BAP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38085 YBR069C TAT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38242 YBR070C ALG14 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P09440 YBR084W MIS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.07442561796378741 0.06215588058250112 0.038902462620469966 0.034414876391641466 0.11016626020974477 -P18238 YBR085W AAC3 0.0002208446925185842 0.00022280058054076116 0.0003374005804309326 0.00042267586462706457 0.0005701378746993962 0.22084469251858418 0.22280058054076116 0.33740058043093263 0.4226758646270646 0.5701378746993963 1000.0 1000.0 1000.0 1000.0 1000.0 +P18238 YBR085W AAC3 0.00022086655330733036 0.00021284332960340901 0.00038761667232187035 0.0004619231462740399 0.0005720700946758386 0.22086655330733035 0.21284332960340901 0.38761667232187036 0.4619231462740399 0.5720700946758386 1000.0 1000.0 1000.0 1000.0 1000.0 P24031 YBR092C PHO3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P00635 YBR093C PHO5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P22219 YBR097W VPS15 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 @@ -72,30 +72,30 @@ Q01976 YBR111C YSA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 P07702 YBR115C LYS2 0.11276340318709324 0.12420664292897146 0.17122289045831482 0.23850067463417446 0.34365375456081504 0.034086674982829246 0.034086674982829246 0.034086674982829246 0.034086674982829246 0.0988513574502048 0.30228490821861576 0.27443520071886957 0.19907779206149914 0.14292066483716775 0.2876481229676525 P33315 YBR117C TKL2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38088 YBR121C GRS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q00764 YBR126C TPS1 0.016084847010432907 0.0198163685173826 0.02371741599897351 0.02639324613163998 0.11559841436858204 0.013323613666687401 0.013323613666687401 0.013323613666687401 0.013323613666687401 0.03863847963339346 0.8283332541519032 0.6723539509774529 0.5617649775702398 0.5048114809460734 0.334247488120346 -P16140 YBR127C VMA2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5532102872696276 0.8353656507375792 0.6894931436089138 0.6539724497539716 0.5431983134887567 +Q00764 YBR126C TPS1 0.07115739113938299 0.08952681338470982 0.11748358511109494 0.15131363948350265 0.5695425042211419 0.013323613666687401 0.013323613666687401 0.013323613666687401 0.013323613666687401 0.03863847963339346 0.18724145803194397 0.14882260590951543 0.11340830001134468 0.08805295882226163 0.06784125740752601 +P16140 YBR127C VMA2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.47360165653982733 0.6097861702171545 0.5619594184960448 0.4637685774912418 0.35557631100639675 P38270 YBR128C ATG14 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38090 YBR132C AGP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P38113 YBR145W ADH5 0.0 0.005005623420005001 0.0 0.0 0.0 0.0 6.552931858380284e-05 0.0 0.0 0.0 0.01996662885874232 0.013091140320687042 0.0051548774759131045 0.004703462581027407 0.009407047876184066 +P38113 YBR145W ADH5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.01996662885874232 0.013091140320687042 0.0051548774759131045 0.004703462581027407 0.009407047876184066 P38279 YBR147W RTC2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38115 YBR149W ARA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3249191466852443 0.32292286888139143 0.18646254778311044 0.16035761599999998 0.09167513827773048 -P33312 YBR153W RIB7 5.311659714204637e-08 5.311659714204637e-08 5.311659714204637e-08 5.311659714204637e-08 1.5403813171193444e-07 5.311659714204637e-05 5.311659714204637e-05 5.311659714204637e-05 5.311659714204637e-05 0.00015403813171193444 1000.0 1000.0 1000.0 1000.0 1000.0 -P38286 YBR159W IFA38 1.0 0.6577261511705318 0.5569692108680334 0.42875310742765227 1.0 0.023147750106680166 0.029990421024164243 0.020186394627915088 0.01972280631101205 0.02900757879353351 0.023147750106680166 0.04559712422988102 0.03624328640438617 0.046000381033600025 0.02900757879353351 +P33312 YBR153W RIB7 5.311659714204637e-08 5.311659714204563e-08 5.311659714204637e-08 5.311659714204637e-08 1.5403813171193444e-07 5.311659714204637e-05 5.3116597142045634e-05 5.311659714204637e-05 5.311659714204637e-05 0.00015403813171193444 1000.0 1000.0 1000.0 1000.0 1000.0 +P38286 YBR159W IFA38 1.0 0.6540321889533526 0.5569692114421728 0.6482986944882951 1.0 0.023147750106680166 0.029821986970047034 0.02018639464872379 0.02982198697004703 0.02900757879353351 0.023147750106680166 0.04559712422988102 0.03624328640438617 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6.963555310723966e-06 0.005556845655198814 0.0071725401089092165 0.0 0.0 0.006963555310723966 1000.0 1000.0 1000.0 1000.0 1000.0 +P25358 YCR034W ELO2 5.556845655198815e-06 7.159062023746221e-06 0.0 7.1590620237462205e-06 6.963555310723966e-06 0.005556845655198815 0.007159062023746221 0.0 0.00715906202374622 0.006963555310723966 1000.0 1000.0 1000.0 1000.0 1000.0 P25332 YCR036W RBK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.10805283191892673 0.10916457573536319 0.07890136376926143 0.057802100497989395 0.062133034254344556 P25360 YCR037C PHO87 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P25628 YCR048W ARE1 0.0 0.0 2.1221371743995378e-06 2.122137173491597e-06 0.00010252783663870641 0.0 0.0 0.002122137174399538 0.002122137173491597 0.1025278366387064 1000.0 1000.0 1000.0 1000.0 1000.0 -P16120 YCR053W THR4 0.0002294748913765342 0.00021495267142013702 0.0003959085852787462 0.0004568311818380894 0.000837115957766548 9.202297541137187e-05 9.202297541137187e-05 9.340982128787836e-05 9.202297541137187e-05 0.00026686662869297836 0.4010154438220251 0.4281080798084515 0.23593785222442595 0.2014375967969427 0.31879290582990083 +P25628 YCR048W ARE1 0.0 0.0 2.122137174496394e-06 0.0 0.00010252783663870641 0.0 0.0 0.002122137174496394 0.0 0.1025278366387064 1000.0 1000.0 1000.0 1000.0 1000.0 +P16120 YCR053W THR4 0.0002294748913765342 0.00021495267142013702 0.00039590858527873774 0.0004568311818380894 0.000837115957766548 9.202297541137187e-05 9.202297541137187e-05 9.340982128787637e-05 9.202297541137187e-05 0.00026686662869297836 0.4010154438220251 0.4281080798084515 0.23593785222442595 0.2014375967969427 0.31879290582990083 P25641 YCR068W ATG15 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P17261 YCR075C ERS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P25372 YCR083W TRX3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03406676137678612 0.0370320135747965 0.022749717496179985 0.01842310690374681 0.008462111967994946 P25346 YCR098C GIT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P25377 YCR105W ADH7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P25612 YCR107W AAD3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q12165 YDL004W ATP16 1.0000000000000002 0.9999999999999999 1.0 1.0 1.000000000000373 0.37198876898682526 0.4739134756020496 0.6520197369797612 0.8042769299008827 1.0909521584640804 0.3719887689868252 0.47391347560204966 0.6520197369797612 0.8042769299008827 1.0909521584636734 -Q99190 YDL015C TSC13 0.15434211366550224 0.09607994384316983 1.0 1.0 0.2308968156566791 0.009966365805277934 0.012912507919932197 0.08223331067052125 0.07237594727561514 0.01248934086679754 0.0645732105682933 0.1343933749691729 0.08223331067052125 0.07237594727561514 0.0540905721513629 -Q00055 YDL022W GPD1 0.0006877116322591105 0.001023757783945215 0.014381626447223864 0.02911698093764816 0.007576054453551733 0.0007335101169201178 0.0007303463448745725 0.007480141757358411 0.012539624202895137 0.0021254677370704618 1.066595477686717 0.7133975988539648 0.5201179285811814 0.4306636127470704 0.2805507471074235 -P52290 YDL024C DIA3 1.7221699198018478e-09 1.7221699198018478e-09 1.7221699198018478e-09 1.7221699198018478e-09 4.9942927674253584e-09 1.7221699198018478e-06 1.7221699198018478e-06 1.7221699198018478e-06 1.7221699198018478e-06 4.994292767425358e-06 1000.0 1000.0 1000.0 1000.0 1000.0 -P12945 YDL040C NAT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.07238537838341734 0.060064505974074194 0.03742441044252903 0.03054439955847836 0.06263220342604778 +Q12165 YDL004W ATP16 0.1860667845457803 0.2792293484145761 0.5299665414308692 0.8820433979562665 0.5896040184072174 0.01958796652146728 0.026652317419604298 0.034604019209996645 0.044558111360567663 0.05322643016504525 0.10527384868441048 0.09544955632684138 0.06529472429819519 0.05051691499965962 0.090274876872165 +Q99190 YDL015C TSC13 0.15434211366550227 0.09554033373073359 1.0 0.177406837203227 0.2308968156566791 0.009966365805277936 0.012839987895754397 0.08223331067052125 0.012839987895754395 0.01248934086679754 0.0645732105682933 0.1343933749691729 0.08223331067052125 0.07237594727561514 0.0540905721513629 +Q00055 YDL022W GPD1 0.0006866688341257548 0.0010237577839452207 0.014381626447222828 0.02911698093764816 0.007577143757219666 0.0007323978731469405 0.0007303463448745765 0.007480141757357873 0.012539624202895137 0.002125773342028327 1.066595477686717 0.7133975988539648 0.5201179285811814 0.4306636127470704 0.2805507471074235 +P52290 YDL024C DIA3 1.7221699198018387e-09 0.0 1.7221699198018478e-09 1.7221699198018478e-09 0.0 1.7221699198018387e-06 0.0 1.7221699198018478e-06 1.7221699198018478e-06 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P12945 YDL040C NAT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.07238537838341734 0.060064505974074194 0.03742441044252903 0.0339402398 0.06263220342604778 P06700 YDL042C SIR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 0.0014127932697033877 0.0009618997185211998 1000.0 -P38913 YDL045C FAD1 1.1094256898262332e-07 1.1094256898262332e-07 1.1094256898262332e-07 1.1094256898262332e-07 3.217334500496076e-07 0.00011094256898262331 0.00011094256898262331 0.00011094256898262331 0.00011094256898262331 0.0003217334500496076 1000.0 1000.0 1000.0 1000.0 1000.0 +P38913 YDL045C FAD1 1.1094256898262332e-07 1.1094256898246937e-07 1.1094256898262332e-07 1.1094256898262332e-07 3.217334500496076e-07 0.00011094256898262331 0.00011094256898246937 0.00011094256898262331 0.00011094256898262331 0.0003217334500496076 1000.0 1000.0 1000.0 1000.0 1000.0 P33333 YDL052C SLC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04517264558885751 0.03422191643907132 0.024369826084604387 0.018369739820839122 0.05172672579217741 P41940 YDL055C PSA1 0.007285621566247441 0.009076480205407297 0.010421997924201638 0.010492528979721874 0.025288363248479075 0.003938647076172651 0.003938647076172651 0.003938647076172651 0.003938647076172651 0.011422076520900685 0.5406054981526174 0.43393991801207354 0.37791670127149496 0.37537633527480163 0.45167322252805925 -P21954 YDL066W IDP1 0.14417034789896635 0.0 0.0 0.0 0.0 0.04602567845162748 0.0 0.0 0.0 0.0 0.3192451091529721 0.3189371226711067 0.22150527782525947 0.19876369353338216 0.2598034709725273 -P07255 YDL067C COX9 0.4064403832321701 0.6617329222160458 0.999999999999984 1.0000000000000384 1.000000000000396 0.015036869165625544 0.021107594177653736 0.027299400511890295 0.03358213271868761 0.044997049918058606 0.03699649391639331 0.031897452082280446 0.027299400511890733 0.03358213271868632 0.04499704991804079 -P32419 YDL078C MDH3 0.0 6.186843215499791e-08 1.14985561645823e-05 7.133119396106185e-06 0.0 0.0 1.3158875200942381e-08 1.2704172638249446e-06 6.193881272471592e-07 0.0 0.3905499152702675 0.2126912666539808 0.11048493790360107 0.08683271551367411 0.12916310745416884 -Q07471 YDL080C THI3 0.0 0.0 0.0 0.0004512547064231948 0.0 0.0 0.0 0.0 0.45125470642319476 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q07500 YDL085W NDE2 0.9540461927230124 1.0 1.0 0.00017590324230978876 0.00022455820046746817 0.060699824583770476 0.028322577935113682 0.006970025919798564 0.17590324230978877 0.22455820046746816 0.0636235698509762 0.028322577935113682 0.006970025919798564 1000.0 1000.0 -P22007 YDL090C RAM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P21954 YDL066W IDP1 0.14417034790031721 0.0 0.0 0.476220807067887 0.0 0.04602567845205873 0.0 0.0 0.0946554065502614 0.0 0.3192451091529721 0.3189371226711067 0.22150527782525947 0.19876369353338216 0.2598034709725273 +P07255 YDL067C COX9 0.20151667323204328 0.32950143624461603 0.5389014434584413 0.8953092692728255 0.8482724115955427 0.006384048036007525 0.009041335822951137 0.011638723844479235 0.014486877294419075 0.017686946501250668 0.031679999146553964 0.02743944283216723 0.0215971287250352 0.016180863743525616 0.020850550200003235 +P32419 YDL078C MDH3 0.0 0.0 1.1393010972660715e-05 1.1582439439168412e-06 0.0 0.0 0.0 1.2587561098494648e-06 1.0057346687756698e-07 0.0 0.3905499152702675 0.2126912666539808 0.11048493790360107 0.08683271551367411 0.12916310745416884 +Q07471 YDL080C THI3 0.0 0.0 0.0 0.00041370850625320764 0.0 0.0 0.0 0.0 0.41370850625320765 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q07500 YDL085W NDE2 0.9540448705426727 1.0 1.0 0.0001805323194467219 0.00021231638069285668 0.06069974046193728 0.028322577935113682 0.006970025919798564 0.1805323194467219 0.2123163806928567 0.0636235698509762 0.028322577935113682 0.006970025919798564 1000.0 1000.0 +P22007 YDL090C RAM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.015407962305587603 0.019725402479977717 0.009684764424907262 1000.0 0.009385072591426248 P52867 YDL093W PMT5 2.331771784986679e-05 2.331771784986679e-05 2.331771784986679e-05 2.331771784986679e-05 6.762138176461369e-05 0.02331771784986679 0.02331771784986679 0.02331771784986679 0.02331771784986679 0.06762138176461369 1000.0 1000.0 1000.0 1000.0 1000.0 -P33775 YDL095W PMT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.13537446162585257 0.15056258595198038 0.10673921912847434 0.10307033315987824 0.13591362992057812 +P33775 YDL095W PMT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0951910869057421 0.11029995094216685 0.07926936368400812 0.07325847183927733 0.10136036236167449 Q12154 YDL100C GET3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.31664532771745874 0.2228288914362265 0.15516212868142043 0.14206249179719296 0.13220485724207337 P43123 YDL103C QRI1 0.003287837532388099 0.004774630366658245 0.007433540635123643 0.007990783035914535 0.02323977548877764 0.00029226119444444447 0.00029226119444444447 0.00029226119444444447 0.00029226119444444447 0.0008475574638888889 0.08889161692614492 0.06121127124003896 0.03931655301156274 0.03657478786883313 0.03647012271259547 Q07540 YDL120W YFH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q12122 YDL131W LYS21 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.40455898024703796 0.2579563243848051 0.20864871145702701 0.20265985644751916 0.27989250126856896 -P48445 YDL141W BPL1 0.00030880611430031315 0.9913944399697855 0.00037301606896794805 1.0000000000000002 0.0008955377314686622 0.30880611430031313 0.3092101513926891 0.37301606896794803 0.3278241363296196 0.8955377314686622 1000.0 0.31189417544253406 1000.0 0.32782413632961954 1000.0 +P48445 YDL141W BPL1 0.0003088061142995392 0.9900990099009905 0.00037301606896794805 1.0000000000028544 0.0008955377314686623 0.3088061142995392 0.30880611429953886 0.37301606896794803 0.31189417544342446 0.8955377314686623 1000.0 0.3118941754425341 1000.0 0.31189417544253417 1000.0 Q07560 YDL142C CRD1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q12055 YDL166C FAP7 1.0 1.0 1.0 1.0 1.0 0.002835505907089258 0.0023916502418240603 0.0013628593424865666 0.001555753437241106 0.0015043242809004889 0.002835505907089258 0.0023916502418240603 0.0013628593424865666 0.001555753437241106 0.0015043242809004889 P32771 YDL168W SFA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.159274916534933 0.11451202121722903 0.059752190990769984 0.054695730936560265 0.05089231992705702 Q12680 YDL171C GLT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.16167788184434287 0.8073932926177062 0.4888426669393213 0.3393987861025965 0.19792216881144173 -P32891 YDL174C DLD1 0.0 0.8453630728097136 0.0 0.0 0.0 0.0 0.10501347129527576 0.0 0.0 0.0 0.3084533914960523 0.12422292228384774 0.05674846219444069 0.04565462891219134 0.28049216584492015 -P46681 YDL178W DLD2 0.0 1.0 0.0 0.0 0.0 0.0 0.03986108872039971 0.0 0.0 0.0 0.05526599976307673 0.03986108872039971 0.023864530792483827 0.020293363200000004 0.034335117364842876 +P32891 YDL174C DLD1 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.05674846219444069 0.04565462891219134 0.0 0.3084533914960523 0.12422292228384774 0.05674846219444069 0.04565462891219134 0.28049216584492015 +P46681 YDL178W DLD2 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.023864530792483827 0.020293363200000004 0.0 0.05526599976307673 0.03986108872039971 0.023864530792483827 0.020293363200000004 0.034335117364842876 P48570 YDL182W LYS20 0.16022129205629293 0.254783497952349 0.40801327889585925 0.4336224657438433 0.3884348035380959 0.3461329320472277 0.3461329320472277 0.3461329320472277 0.3461329320472277 1.0037855029369602 2.1603429082672463 1.3585374831142454 0.8483374192720189 0.798235699004814 2.584180134719863 -P17255 YDL185W VMA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4262762113443446 1.4971169947798397 1.3362542279616856 1.2656719283210052 1.0249773254192212 -P38988 YDL198C GGC1 0.0 1.0 0.4529139774808741 0.29156306628081846 0.0 0.0 0.11029491388672448 0.035979849329662125 0.021310628451491852 0.0 0.08998862306493623 0.11029491388672448 0.07944080138525092 0.07309097384428849 0.07351524659131961 +P17255 YDL185W VMA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.97294636663692 1.2527178284654723 1.154464657952783 0.9527457224857305 0.7304802993794852 +P38988 YDL198C GGC1 0.0 0.8539564695489654 0.4529139774808741 0.29156306628081613 0.0 0.0 0.0941870552719144 0.035979849329662125 0.021310628451491682 0.0 0.08998862306493623 0.11029491388672448 0.07944080138525092 0.07309097384428849 0.07351524659131961 P28789 YDL205C HEM3 0.0 0.0 0.0 0.0 0.0003994859897636418 0.0 0.0 0.0 0.0 4.7269999880654724e-05 0.11337442335755556 0.052513345414932563 0.03942863390689165 0.033070500717109395 0.11832705299282784 P32837 YDL210W UGA4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P33327 YDL215C GDH2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4446090878686545 0.209872416 0.10858169725380888 0.09052079509713636 0.053402150262246574 @@ -191,10 +191,10 @@ P54854 YDL245C HXT15 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000. Q07786 YDL246C SOR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P0CD99 YDL247W MPH2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P32356 YDR001C NTH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.047095402426228505 0.0429408236363571 0.03602134170310798 0.029748006111396642 0.014441447254058151 -P00912 YDR007W TRP1 4.3389037023237364e-07 7.103265581898482e-07 4.3822927393458834e-07 4.382292739346558e-07 1.2708648944102696e-06 0.00043389037023237366 0.0007103265581898482 0.00043822927393458833 0.00043822927393465577 0.0012708648944102696 1000.0 1000.0 1000.0 1000.0 1000.0 +P00912 YDR007W TRP1 4.3389037023220974e-07 7.103265581898472e-07 4.38229273934602e-07 4.382292739345686e-07 1.2708648944103215e-06 0.0004338903702322097 0.0007103265581898472 0.000438229273934602 0.0004382292739345686 0.0012708648944103214 1000.0 1000.0 1000.0 1000.0 1000.0 P13045 YDR009W GAL3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 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0.9999999999999999 0.4219830452578867 0.048834071963966566 0.06645394774743148 0.0927808160052314 0.09918671238115895 0.12390142169746865 0.2805730300316707 0.1727067615559623 0.125472328 0.09918671238115896 0.2936170613720954 +P13663 YDR158W HOM2 0.9900990099025436 0.9900990099009865 1.0 0.9900990099008555 0.9900990099009831 0.9362269317993981 0.9362269317979269 0.9455892011159102 0.9362269317978027 2.715058102213976 0.9455892011159084 0.9455892011159096 0.9455892011159102 0.9455892011159093 2.742208683236135 P07250 YDR173C ARG82 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.002841544776659587 1000.0 1000.0 1000.0 1000.0 -P37298 YDR178W SDH4 0.0 0.0 0.0 0.5154117368525274 0.0 0.0 0.0 0.0 0.011380394958084412 0.0 0.07829532423036736 0.053286688600257065 0.03669658816111597 0.02208020140864708 0.08678221645841057 +P37298 YDR178W SDH4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03058295967133265 0.02985948013516846 0.030959816942778093 0.03361023711505835 0.05891543919932769 P53688 YDR191W HST4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q03941 YDR196C CAB5 0.0009763678461110039 0.0009256513874777242 0.9042371682020096 1.0 0.007993989924055972 2.590564615584701e-05 2.5905646112927775e-05 0.01520032199977925 0.017352108682007757 7.512637385188585e-05 0.026532670303546415 0.027986395810972838 0.016810105284660724 0.017352108682007757 0.009397856960741377 -O13525 YDR204W COQ4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.012777563198410787 1000.0 0.007127314589952331 0.0062176326322361 1000.0 +Q03941 YDR196C CAB5 0.0009763678489655599 0.000925651389004369 0.9042371682020529 1.0 0.0722191423262302 2.5905646231586e-05 2.5905646155653062e-05 0.015200321999779979 0.017352108682007757 0.0006787051694093346 0.026532670303546415 0.027986395810972838 0.016810105284660724 0.017352108682007757 0.009397856960741377 +O13525 YDR204W COQ4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.01003489125826384 0.00694604692238464 0.003283749108995622 0.0038520294694437325 0.00558272718314312 P38994 YDR208W MSS4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P07170 YDR226W ADK1 0.003371538854299769 0.010563204344362375 0.01557566592186502 0.02679303812876625 0.03775184720012979 0.0024479982520321853 0.0042291871514215495 0.004279046947739157 0.00652533375654943 0.015078107733668534 0.7260774257162187 0.4003697186525303 0.27472642063619623 0.24354586908692258 0.39940052876715115 -Q04935 YDR231C COX20 0.0 0.6617329222160458 1.0 1.0 1.0000000000025877 0.0 0.0720198509942119 0.08162018124756092 0.060719242571883304 0.07914022189659028 0.12623333368744394 0.1088352242669566 0.08162018124756092 0.060719242571883304 0.07914022189638549 +P07170 YDR226W ADK1 0.0033712788706997754 0.011671773188120928 0.01586124072224249 0.029656792412821154 0.04542132434300037 0.0024478094838091737 0.004673024547504122 0.004357501890470755 0.007222789282510979 0.01814130095989862 0.7260774257162187 0.4003697186525303 0.27472642063619623 0.24354586908692258 0.39940052876715115 +Q04935 YDR231C COX20 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.010567823907124527 0.005964123697941728 0.0037114429018009487 0.002433458055803021 0.005409181266758766 P09950 YDR232W HEM1 0.0 0.0 0.0 0.0 1.4613873457833548e-05 0.0 0.0 0.0 0.0 1.9924745320065227e-07 0.008832927612623222 0.005847463403844133 0.004681182269456532 0.004125484462628715 0.013634130182908396 P49367 YDR234W LYS4 0.8966383088030373 1.0 1.0 1.0 1.0 0.5450067520415278 0.41639136396627413 0.3495680924942362 0.37736103598279236 1.1805435772535076 0.6078334448692938 0.41639136396627413 0.3495680924942362 0.37736103598279236 1.1805435772535076 -Q03778 YDR236C FMN1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q03778 YDR236C FMN1 0.0 6.815833161141442e-08 0.0 0.0 1.9765916167337606e-07 0.0 6.815833161141441e-05 0.0 0.0 0.00019765916167337606 1000.0 1000.0 1000.0 1000.0 1000.0 P22580 YDR242W AMD2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q03786 YDR248C YDR248C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0203637188803726 0.01844875574987552 0.008501529315850647 0.008006924164058614 0.00469389079539558 -P15202 YDR256C CTA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9673679177948252 0.142313999298517 0.011912076673005369 0.005288523437459668 0.02088139569202663 +P15202 YDR256C CTA1 0.0 0.0 0.0 6.433549572969499e-07 0.0 0.0 0.0 0.0 3.4023977702707833e-09 0.0 0.9673679177948252 0.142313999298517 0.011912076673005369 0.005288523437459668 0.02088139569202663 P52911 YDR261C EXG2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P04803 YDR268W MSW1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.006396754833292535 0.0043346187923916715 0.0034424066533227235 0.0025444412510121604 0.0036176809074877697 P38995 YDR270W CCC2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q05584 YDR272W GLO2 0.0 0.015686606771921678 0.0 0.0 0.0 0.0 0.0007507204676283365 0.0 0.0 0.0 0.03629572298364445 0.04785741610939674 0.031489341733433665 0.02779674490455528 0.020965058900730558 +Q05584 YDR272W GLO2 0.0 0.0 0.013134820399770264 0.013910806546856492 0.0 0.0 0.0 0.0004136068481756416 0.0003866751409995874 0.0 0.03629572298364445 0.04785741610939674 0.031489341733433665 0.02779674490455528 0.020965058900730558 Q05521 YDR284C DPP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q05533 YDR287W INM2 2.8483259106279964e-08 2.8483259106279964e-08 2.7465441344488968e-08 2.746544134439346e-08 7.963424436676666e-08 2.8483259106279965e-05 2.8483259106279965e-05 2.746544134448897e-05 2.746544134439346e-05 7.963424436676667e-05 1000.0 1000.0 1000.0 1000.0 1000.0 +Q05533 YDR287W INM2 2.8448010369557607e-08 2.8483259106279964e-08 2.7465441344393637e-08 2.746544134439338e-08 7.963424436676828e-08 2.844801036955761e-05 2.8483259106279965e-05 2.7465441344393637e-05 2.746544134439338e-05 7.963424436676828e-05 1000.0 1000.0 1000.0 1000.0 1000.0 Q05567 YDR294C DPL1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.11978849854919763 0.10084817820225084 0.05351458988984713 0.03769412889116117 0.042220892131775954 P38992 YDR297W SUR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.01791713576389021 0.03399542998040653 0.03271295072509868 0.02568355890153404 0.016089045324467477 -P09457 YDR298C ATP5 0.9999999999999999 1.0 1.0 1.0 1.0000000000003733 0.4986223134938561 0.635244537742959 0.8739822725885003 1.0780713207261305 1.4623373997179516 0.49862231349385616 0.635244537742959 0.8739822725885003 1.0780713207261305 1.4623373997174058 -P32264 YDR300C PRO1 1.0 1.0 1.0 1.0 1.000000000000001 0.08752024352197224 0.08897571218087687 0.006486823808271518 0.005750759849711341 0.018532011528914486 0.08752024352197224 0.08897571218087687 0.006486823808271518 0.005750759849711341 0.018532011528914465 +P09457 YDR298C ATP5 0.18606678454578024 0.2792293484145761 0.5299665414308693 0.8820433979562665 0.5896040184072173 0.02625616147007958 0.03572538011814644 0.04638402433941618 0.05972671871797829 0.07134593288985559 0.1411114914151669 0.127942783668658 0.08752255229959018 0.06771403635735808 0.1210065241458033 +P32264 YDR300C PRO1 1.0 1.0 1.0 1.0000000000000002 1.000000000000001 0.08752024352197224 0.08897571218087687 0.006486823808271518 0.0057507598497113415 0.018532011528914486 0.08752024352197224 0.08897571218087687 0.006486823808271518 0.005750759849711341 0.018532011528914465 Q06636 YDR302W GPI11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P49775 YDR305C HNT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.003706155436570733 0.0031608876254864272 0.0020630843274484704 0.0017091699527977948 0.0015170737609786636 Q06667 YDR315C IPK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38986 YDR321W ASP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03965822327271666 0.0303437262277729 0.014789096593048369 0.013986908611638307 0.0405676592917633 -P81449 YDR322C-A TIM11 1.0 1.0 0.9999999999999999 1.0 1.0000000000003733 0.23770563169804415 0.30283683670081624 0.41664903991726693 0.5139433542656875 0.6971325308728167 0.23770563169804415 0.30283683670081624 0.416649039917267 0.5139433542656875 0.6971325308725564 +P81449 YDR322C-A TIM11 0.18606678454578027 0.27922934841457603 0.5299665414308692 0.8820433979562665 0.5896040184072172 0.012516963800674389 0.01703117533816782 0.02211241556568293 0.02847320911618883 0.03401237687867403 0.06727135007589002 0.060993500270900516 0.0417241728241581 0.032280961664882375 0.05768681321161378 Q05506 YDR341C YDR341C 0.04512172443690605 0.07169555382940941 0.10894177921152458 0.12189404030293884 0.25584401215138936 0.014432097934099927 0.014432097934099927 0.014432097934099927 0.014432097934099927 0.041853084008889783 0.31984810231001715 0.20129697259106605 0.13247532800137346 0.11839871660855902 0.16358828825794156 P39004 YDR342C HXT7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6624045583359158 0.7282362643500863 0.20571056036998536 0.2424373273643552 0.9588069202536764 P39003 YDR343C HXT6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P32466 YDR345C HXT3 0.0015694782316599115 0.0020793628830928714 0.0028330925929567893 0.004540681069070014 0.007619558160691372 1.5694782316599116 2.0793628830928714 2.833092592956789 4.540681069070014 7.619558160691372 1000.0 1000.0 1000.0 1000.0 1000.0 Q06328 YDR352W YPQ2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P29509 YDR353W TRR1 0.012668356703373183 0.01941273075680828 0.06855823652615033 0.054481608736638126 0.07882921931371366 0.0037485059674064168 0.0037927481997475972 0.007973526872366611 0.005702296341168259 0.0108706673054786 0.29589520213054216 0.1953742751218777 0.11630297505282608 0.10466461019411022 0.1379014964263063 -P07285 YDR354W TRP4 0.4361512711939023 1.0 1.0 1.0 1.0 0.01275378408168775 0.02087935610506848 0.01288132192250142 0.012881321922503405 0.03735583357525305 0.02924165289436409 0.02087935610506848 0.01288132192250142 0.012881321922503405 0.03735583357525305 +P29509 YDR353W TRR1 0.012668356703426805 0.019186282150339382 0.06842982750922857 0.03581445495715392 0.07882921931371192 0.003748505967422283 0.0037485059674063773 0.007958592521675002 0.0037485059674050338 0.010870667305478362 0.29589520213054216 0.1953742751218777 0.11630297505282608 0.10466461019411022 0.1379014964263063 +P07285 YDR354W TRP4 0.43615127119373753 0.9999999999999983 1.0 1.0 1.0 0.012753784081682932 0.020879356105068445 0.012881321922501823 0.01288132192250084 0.03735583357525457 0.02924165289436409 0.02087935610506848 0.012881321922501823 0.01288132192250084 0.03735583357525457 Q06346 YDR367W KEI1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q12458 YDR368W YPR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.11706552922088552 0.12408355386777761 0.09538961591325684 0.08752853134022819 0.04803706785293959 Q06350 YDR371W CTS2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q06389 YDR373W FRQ1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P48360 YDR376W ARH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.02382838814950288 0.014557545556590031 0.009309666543780277 0.01644000723359696 -Q06405 YDR377W ATP17 1.0 0.9999999999999998 1.0 1.0 1.0000000000003733 0.24723483870616728 0.3149770408936772 0.4333517781853737 0.534546453057508 0.7250793664245405 0.24723483870616728 0.31497704089367723 0.4333517781853737 0.534546453057508 0.7250793664242698 +Q06405 YDR377W ATP17 0.1860667845457803 0.27922934841457614 0.5299665414308693 0.8820433979562665 0.5896040184072173 0.01301874719687649 0.01771392565514476 0.022998864001379675 0.029614650746812066 0.035375874149647 0.06996814196933321 0.06343862404049527 0.04339682263579224 0.03357504949918623 0.059999377625025295 Q06408 YDR380W ARO10 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q12359 YDR384C ATO3 0.00037253831144999633 0.0003947346528379811 0.0005506056135202446 0.0007025845189384373 0.0010793726820855494 0.37253831144999633 0.3947346528379811 0.5506056135202446 0.7025845189384373 1.0793726820855494 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12359 YDR384C ATO3 0.00037250705175008285 0.00039473465283797665 0.0005506056135201768 0.0007161244430239306 0.0010793726820855875 0.37250705175008286 0.39473465283797665 0.5506056135201769 0.7161244430239306 1.0793726820855876 1000.0 1000.0 1000.0 1000.0 1000.0 Q04162 YDR387C CIN10 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q04178 YDR399W HPT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.20806795878156806 0.31167465368477687 0.21558617612485328 0.1925737021835881 0.1339285278856101 Q04179 YDR400W URH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P21595 YDR402C DIT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P21623 YDR403W DIT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P04161 YDR408C ADE8 0.026002493343028777 0.05239763639837232 0.08221943524791289 0.08267574284772916 0.11454373830821031 0.0016740252577018696 0.0016740252577017612 0.0016740252577007832 0.0016740252577079487 0.0048546732473318845 0.06437941299004978 0.031948488 0.020360456778292912 0.020248082448937183 0.0423827030533009 -Q04066 YDR428C BNA7 3.140879386131227e-08 1.785722011503037e-07 3.371865009769967e-08 3.371865009773558e-08 9.778408528330969e-08 3.1408793861312273e-05 0.0001785722011503037 3.371865009769967e-05 3.371865009773558e-05 9.77840852833097e-05 1000.0 1000.0 1000.0 1000.0 1000.0 +P04161 YDR408C ADE8 0.02600249334316454 0.05239763639836051 0.08221943524792431 0.08267574284738753 0.11454373830822331 0.00167402525771061 0.0016740252577013839 0.0016740252577010157 0.0016740252577010313 0.004854673247332435 0.06437941299004978 0.031948488 0.020360456778292912 0.020248082448937183 0.0423827030533009 +Q04066 YDR428C BNA7 3.140879386122502e-08 1.785722011503031e-07 3.371865009770694e-08 3.3718650097689163e-08 9.778408528333725e-08 3.140879386122502e-05 0.0001785722011503031 3.371865009770694e-05 3.3718650097689166e-05 9.778408528333725e-05 1000.0 1000.0 1000.0 1000.0 1000.0 Q04082 YDR437W GPI19 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P36973 YDR441C APT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q04119 YDR452W PPN1 1.0 1.0 1.0 1.0 1.0 0.027093493784673277 0.028157487121690496 0.021577302748399124 0.017132724341726295 0.01393042489424953 0.027093493784673277 0.028157487121690496 0.021577302748399124 0.017132724341726295 0.01393042489424953 Q04120 YDR453C TSA2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.003845944885811796 1000.0 1000.0 1000.0 -P15454 YDR454C GUK1 3.57766588908224e-05 4.6176086559158366e-05 7.790652771752976e-05 8.212650162728824e-05 0.00021408120299908073 8.53094965884862e-06 8.530949658848217e-06 8.53094965884862e-06 8.530949658851043e-06 2.4739754010660652e-05 0.23845014943631365 0.18474821697847466 0.10950237302039416 0.10387572208501886 0.11556247659336483 +P15454 YDR454C GUK1 3.57766588908224e-05 4.617608655916055e-05 7.790652771752976e-05 8.212650162724353e-05 0.00021408120299908073 8.53094965884862e-06 8.53094965884862e-06 8.53094965884862e-06 8.530949658846398e-06 2.4739754010660652e-05 0.23845014943631365 0.18474821697847466 0.10950237302039416 0.10387572208501886 0.11556247659336483 Q04121 YDR456W NHX1 1.3462747289314673e-06 1.3462747289314673e-06 1.3462747289314673e-06 1.3462747289314673e-06 3.904196713901254e-06 0.0013462747289314672 0.0013462747289314672 0.0013462747289314672 0.0013462747289314672 0.0039041967139012545 1000.0 1000.0 1000.0 1000.0 1000.0 -P11491 YDR481C PHO8 3.697938081816464e-05 2.384131384212846e-05 3.0058812230190497e-05 3.044955605296249e-05 0.00034706529101277624 3.99066889499834e-06 3.990668894998343e-06 3.990668894998343e-06 3.990668895103167e-06 1.1572939795498691e-05 0.10791605502053414 0.16738460478409908 0.13276202880000001 0.1310583605278839 0.03334513734210508 +P11491 YDR481C PHO8 3.697938081816467e-05 2.384131384211827e-05 3.0058812230190497e-05 3.0449556051362845e-05 0.00034706529101277624 3.990668894998343e-06 3.990668894996637e-06 3.990668894998343e-06 3.9906688948935204e-06 1.1572939795498691e-05 0.10791605502053414 0.16738460478409908 0.13276202880000001 0.1310583605278839 0.03334513734210508 P27809 YDR483W KRE2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.011994985983809393 0.015260516857097827 0.011211907156338486 0.010080679386986582 0.010175438759365416 -Q99258 YDR487C RIB3 0.003296312960458002 0.0039112079986464545 0.007536084894161825 0.009024867789587233 0.015308120330809725 0.0005698989734288502 0.0005698989734288502 0.0005698989734288502 0.0005698989734288502 0.0016527070229436654 0.172889825773602 0.14570919614248953 0.0756226849130042 0.06314762572881032 0.10796276663813273 +Q99258 YDR487C RIB3 0.003296312960458002 0.0039112079986464016 0.007536084894161825 0.009024867789587233 0.015308120330809725 0.0005698989734288502 0.0005698989734288424 0.0005698989734288502 0.0005698989734288502 0.0016527070229436654 0.172889825773602 0.14570919614248953 0.0756226849130042 0.06314762572881032 0.10796276663813273 P30605 YDR497C ITR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P19358 YDR502C SAM2 0.006395228186938011 0.008668775396352886 0.009799843740905822 0.011210853818094845 0.02862478253353273 0.022041397261908475 0.025618998419739258 0.02415631932345529 0.024000777066618316 0.06689292203398585 3.44653804643392 2.955319205815119 2.464969846674562 2.1408518437623307 2.336888392274198 -Q04396 YDR503C LPP1 3.3152784161283973e-07 1.0085118162749855e-16 3.111910298812901e-07 3.247119267669737e-07 1.1339632746609568e-06 0.0003315278416128397 1.0085118162749855e-13 0.0003111910298812901 0.0003247119267669737 0.0011339632746609567 1000.0 1000.0 1000.0 1000.0 1000.0 -P48813 YDR508C GNP1 1.408461513368406e-07 1.4084615133784363e-07 1.4084615133377842e-07 1.408461516331038e-07 4.084538388764545e-07 0.0001408461513368406 0.00014084615133784362 0.00014084615133377843 0.0001408461516331038 0.0004084538388764545 1000.0 1000.0 1000.0 1000.0 1000.0 +P19358 YDR502C SAM2 0.006384038768998123 0.008668775396352978 0.009799843740905805 0.01121085381808325 0.028624782533504225 0.0220028325072612 0.025618998419739525 0.024156319323455248 0.024000777066593492 0.06689292203391924 3.44653804643392 2.955319205815119 2.464969846674562 2.1408518437623307 2.336888392274198 +Q04396 YDR503C LPP1 3.629907833906543e-07 3.858733766492932e-07 3.1119102992143844e-07 3.247119267668969e-07 1.133963274660959e-06 0.0003629907833906543 0.0003858733766492932 0.0003111910299214384 0.0003247119267668969 0.001133963274660959 1000.0 1000.0 1000.0 1000.0 1000.0 +P48813 YDR508C GNP1 1.408461517486252e-07 1.4084615133578613e-07 1.4084615133773915e-07 1.408461513008937e-07 4.084538388703849e-07 0.0001408461517486252 0.00014084615133578613 0.00014084615133773916 0.0001408461513008937 0.00040845383887038486 1000.0 1000.0 1000.0 1000.0 1000.0 P17695 YDR513W GRX2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.15557039084034818 0.14124242665854606 0.0842190438194639 0.06677733766193839 0.04075290282420548 Q04409 YDR516C EMI2 0.19854888048801736 0.5546223349885118 1.0 1.0 1.0 0.046785044945593504 0.06198434867160301 0.046325028146612615 0.03940980015693188 0.09355400173906059 0.23563489670956383 0.11175956098646286 0.046325028146612615 0.03940980015693188 0.09355400173906059 -P00128 YDR529C QCR7 0.5821562574079976 0.9338617272706928 0.9999999999999836 1.0000000000000395 1.0000000000003961 0.07451293051132796 0.10341919828557897 0.1349195505662305 0.1661276857161958 0.2229760741300948 0.12799472575127954 0.11074358790549457 0.13491955056623273 0.16612768571618924 0.22297607413000647 +P00128 YDR529C QCR7 0.20484506483564066 0.3048373008509114 0.420838398545406 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0.00033320208301376817 0.00033061162316296185 0.0003347651122636555 0.000334765112263654 0.0009708637297525352 2.5671891881927253 2.1015593813652704 1.5878213532396845 1.1789808894923401 2.87487316835351 +P10869 YER052C HOM3 0.011990726109505379 0.017635219496535046 0.035065535861545705 0.03854494398802555 0.030029808370288368 0.0025202403312038456 0.002520240331199885 0.0025454427345118946 0.002520240331199551 0.007308696960479634 0.21018246169479107 0.14290949606241418 0.072591012 0.06538445955408559 0.24338140524769025 +P40035 YER053C PIC2 1.0 1.0 1.0 1.0 0.0 0.022899157793307576 0.017308646894449074 0.0239447428474692 0.015195171298939047 0.0 0.022899157793307576 0.017308646894449074 0.0239447428474692 0.015195171298939047 0.02664768541735028 P00498 YER055C HIS1 0.03823881714799629 0.022596913878240515 0.04574455294340898 0.046515652677831164 0.11451516135311375 0.0069351225554408645 0.0069351225554408645 0.0069351225554408645 0.0069351225554408645 0.020111855410778503 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0.5845578504477592 0.5802740778505087 0.588276790101759 0.5882767901017554 1.706109532523549 0.5845578504477592 0.5802740778505087 0.588276790101759 0.5882767901017554 1.706109532523549 +P53037 YGR170W PSD2 1.317711571010867e-07 0.0 0.0 0.0 2.8857862611939877e-07 0.0001317711571010867 0.0 0.0 0.0 0.0002885786261193988 1000.0 1000.0 1000.0 1000.0 1000.0 P22438 YGR171C MSM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P32476 YGR175C ERG1 0.9900990099054359 1.0000000000026719 0.9999999999650592 0.9999999999885618 0.9900990099009901 0.5943444739057422 0.6002879186437081 0.6002879186211296 0.600287918635238 1.7235989743189126 0.6002879186421042 0.6002879186421042 0.6002879186421042 0.6002879186421042 1.7408349640621017 +P32476 YGR175C ERG1 0.9900990099009901 1.0000000000008407 1.000000000000452 0.9900990099039315 0.9900990099009901 0.5943444739030734 0.6002879186426088 0.6002879186423754 0.5943444739048391 1.7235989743189126 0.6002879186421042 0.6002879186421042 0.6002879186421041 0.6002879186421042 1.7408349640621017 P53296 YGR177C ATF2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P49723 YGR180C RNR4 0.0015672054466445214 0.0007147930370243784 0.0012627172754422604 0.0016190425410680276 0.018120898113227705 0.0010350129288933287 0.0010350129288933287 0.0010350129288933287 0.0010350129288933287 0.0030015374937906528 0.6604194307194069 1.4479896631366165 0.8196711560240756 0.6392746963959116 0.1656395546752521 -P22289 YGR183C QCR9 0.5821562574079976 0.9338617272706928 0.9999999999999838 1.0000000000000397 1.000000000000396 0.03824638987316772 0.053083551416614375 0.06925221833389217 0.08527089450149536 0.11445033506327418 0.06569780773886481 0.05684305274160504 0.06925221833389329 0.08527089450149197 0.11445033506322887 +P22289 YGR183C QCR9 0.20484506483564066 0.3048373008509114 0.420838398545406 0.892359746616224 0.6186205673623894 0.0076516085454780185 0.010836504057493578 0.013846250824132262 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0.042035396255539016 0.09951677526917795 0.2027232103236882 0.026423093498594525 0.03635455884131801 0.042035396255539016 0.09951677526917795 +P16451 YGR193C PDX1 1.0000000000014375 1.0 0.9999999999999998 1.0000000000000002 1.0 0.2027425849475044 0.2017835006774047 0.29519304396959234 0.33082838447337604 0.39763799330183336 0.20274258494721298 0.2017835006774047 0.2951930439695924 0.330828384473376 0.39763799330183336 P42826 YGR194C XKS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.014887146878343506 0.011024366509686672 0.008062624847576524 0.012311945168487885 -P13259 YGR202C PCT1 0.09914929248740101 0.10548706567183977 0.13068630764367897 0.15808862231450627 0.323826129384176 0.0011653772412938397 0.0014010797924056662 0.0014925909912298992 0.0014925909914113426 0.004149642425785196 0.011753762553998308 0.013282005556627124 0.011421173481306883 0.009441482692169567 0.01281441504944836 -P07245 YGR204W ADE3 0.038656042739238096 0.3115806562665299 1.0 1.0 0.10962727881341507 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0.001401079792405364 0.001492590991412204 0.0014925909914109937 0.004149642425785202 0.011753762553998308 0.013282005556627124 0.011421173481306883 0.009441482692169567 0.01281441504944836 +P07245 YGR204W ADE3 0.03865604273935987 0.31158065626656856 1.0 1.0 0.10962727881346977 0.03482319641947348 0.19361243351283242 1.414288197223803 1.970425541332419 0.09914881834080104 0.9008474213015147 0.6213878481184979 1.414288197223803 1.970425541332419 0.9044173987890571 +P42941 YGR208W SER2 0.01939726015856476 0.0266554617948366 0.12962227327586506 0.18334997102686762 0.07878129207931832 0.0005555186813977453 0.0008213136926458729 0.002541703706744123 0.0033328507691181178 0.0016018176408096152 0.02863902823680275 0.03081221023171201 0.019608541360286218 0.018177536382755852 0.02033246216877071 +P22803 YGR209C TRX2 0.0788803777220308 0.05757610724057737 0.11026417304772229 0.10870794351504848 0.811915028864666 0.010603711566595791 0.01060371156654627 0.013104822052774731 0.010603711566542086 0.03075076354298377 0.13442774835539664 0.18416860872930277 0.1188493205957566 0.09754311620359381 0.037874361786335964 P53306 YGR216C GPI1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P50076 YGR227W DIE2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P39676 YGR234W YHB1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4288275794733394 0.7942549774865814 0.5859349794047529 0.34751368927568793 1.6697651253199888 -P16861 YGR240C PFK1 0.05844698152409065 0.0975366908012282 0.1940791309025205 0.3834379374735876 0.4011644963708955 0.057127612290808816 0.09025626516158437 0.13071190904522706 0.2200938602973695 0.34443833903391213 0.9774262211858107 0.9253570571255001 0.6734980130907496 0.5740012627533243 0.8585962669923378 +P16861 YGR240C PFK1 0.04959328030576242 0.0794770894653297 0.1596467268264346 0.30411663533332206 0.342004569738591 0.057129717591667885 0.09025626516158437 0.13094686346371232 0.22107113183053867 0.34664823545122486 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0.028931656145710118 0.024191870604666713 1000.0 -P00924 YGR254W ENO1 0.014753391117839736 0.029906030333254986 0.05769580050900428 0.10912443397552035 0.42824535625850163 0.09283752408190744 0.13421566573545682 0.1846704057332463 0.32096342423381236 0.5493975455867381 6.292622715712371 4.48791311450692 3.2007599184697293 2.941260839032745 1.2829036849032531 -P53318 YGR255C COQ6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 0.002749771514331938 0.002918380322720173 1000.0 +P53315 YGR248W SOL4 1.0 0.0 0.0 0.0 2.6298129761639037e-05 0.05926990877219152 0.0 0.0 0.0 0.026298129761639037 0.05926990877219152 0.045278030658851866 0.028931656145710118 0.024191870604666713 1000.0 +P00924 YGR254W ENO1 0.014754267006498078 0.031127450051487395 0.05711528014066386 0.1097717253468867 0.4296619475450331 0.09284303571877536 0.13969729130722938 0.182812299406407 0.322867276995856 0.5512148957682312 6.292622715712371 4.48791311450692 3.2007599184697293 2.941260839032745 1.2829036849032531 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0.021067660548136406 0.013382237047239195 0.014291117598204268 0.015842999444151264 -P53332 YGR277C CAB4 3.7309855357340064e-08 0.0 2.1891822801291375e-05 2.484383425732929e-05 1.0819858053618465e-07 3.730985535734006e-05 0.0 0.021891822801291375 0.024843834257329292 0.00010819858053618466 1000.0 1000.0 1000.0 1000.0 1000.0 +P51601 YGR267C FOL2 0.05956630684993754 0.059520434900224524 0.09370304185536851 0.0877437547837787 0.22953187213521806 0.0012539563181559175 0.0012539563181553815 0.0012539563181559175 0.0012539563181229796 0.0036364733226532586 0.021051436365107336 0.021067660548136406 0.013382237047239195 0.014291117598204268 0.015842999444151264 +P53332 YGR277C CAB4 3.730985546642095e-08 0.0 2.1891822801292426e-05 2.4825620086839207e-05 0.0 3.7309855466420946e-05 0.0 0.021891822801292427 0.024825620086839206 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P15703 YGR282C BGL2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4243637680502571 0.6131294674448522 0.38330827554766694 0.31983680112247054 0.20907916957277156 P32451 YGR286C BIO2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.00134188235430682 0.0006807531996678273 0.00027980575845156023 0.00018705655000831686 0.0011853498409996187 P53051 YGR287C IMA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P53048 YGR289C MAL11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.026675257484385644 1000.0 0.007876146446988164 0.010531491820459633 0.010871369682091719 P53341 YGR292W MAL12 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P38703 YHL003C LAG1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.011784180910679764 1000.0 1000.0 1000.0 1000.0 +P38703 YHL003C LAG1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.018255158698833276 0.04539539264364164 0.030801331946231112 0.028124855958089348 0.01488471964486548 P38689 YHL011C PRS3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1255293131581557 0.11184662403032673 0.07001421553394094 0.05145678391714023 0.08411136586829483 P38709 YHL012W YHL012W 2.4630850456621006e-05 2.4630850456621006e-05 2.4630850456621006e-05 2.4630850456621006e-05 7.142946632420092e-05 0.024630850456621008 0.024630850456621008 0.024630850456621008 0.024630850456621008 0.07142946632420091 1000.0 1000.0 1000.0 1000.0 1000.0 P33413 YHL016C DUR3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38744 YHL018W YHL018W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P32190 YHL032C GUT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.16185412548661546 0.035545531189201465 0.0075321775761574275 0.0043814663567326925 0.1879855981983816 P38734 YHL036W MUP3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P37299 YHR001W-A QCR10 0.5821562574079976 0.9338617272706926 0.9999999999999836 1.0000000000000395 1.0000000000003961 0.04396083844035985 0.06101484180350017 0.07959929268902291 0.09801134248947961 0.13155052557500202 0.07551381245319226 0.06533605567263405 0.07959929268902421 0.09801134248947574 0.13155052557494992 -P38702 YHR002W LEU5 3.813514262625343e-06 3.848374738852441e-06 5.769808521352122e-06 6.015999665017582e-06 1.1059341306809499e-05 0.003813514262625343 0.0038483747388524414 0.005769808521352122 0.006015999665017582 0.011059341306809498 1000.0 1000.0 1000.0 1000.0 1000.0 -P10614 YHR007C ERG11 0.07494606210888244 0.03558333942697233 0.05585668947096519 0.06829013633077563 0.24241442380938066 0.009329990409543168 0.009423290313621466 0.00942329031326703 0.009423290313488502 0.02705697218755369 0.12448940140428538 0.26482310163611483 0.1687047765006793 0.1379890394103929 0.11161453086153643 +P37299 YHR001W-A QCR10 0.20484506483564066 0.3048373008509114 0.420838398545406 0.8923597466162239 0.6186205673623894 0.008794846472885582 0.012455601841364676 0.01591503923645914 0.019886027990086933 0.024366041448197064 0.042934138930523946 0.040859835087755265 0.03781745984080395 0.02228476583070179 0.03938770020545305 +P38702 YHR002W LEU5 3.8135142626082144e-06 3.844927721589372e-06 5.769808521488445e-06 5.976265874553263e-06 1.0970312710978465e-05 0.0038135142626082143 0.003844927721589372 0.005769808521488445 0.005976265874553263 0.010970312710978465 1000.0 1000.0 1000.0 1000.0 1000.0 +P10614 YHR007C ERG11 0.09714507438407229 0.056014047808831915 0.08578750102668176 0.09897380503003654 0.3365624764562108 0.009329990409501273 0.009423290313604208 0.009423290313600546 0.009329990409528992 0.02705697218755369 0.09604182681063446 0.16823083998079508 0.10984456011452881 0.09426727007916418 0.08039212354403387 P00447 YHR008C SOD2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3103782619925256 0.25322550451725095 0.19367052246884725 0.1466166270819591 0.21208464006810493 P38705 YHR011W DIA4 1.0 1.0 1.0 1.0 1.0 0.004304725671790807 0.004494963142169967 0.002560156491140939 0.0022173670682261045 0.003925578898246396 0.004304725671790807 0.004494963142169967 0.002560156491140939 0.0022173670682261045 0.003925578898246396 -P07347 YHR013C ARD1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.023337811647239682 0.02493892875634107 0.013577663835277344 0.012649203828137475 0.017676810447700215 +P07347 YHR013C ARD1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.020201745104064188 0.016763162210225672 0.010444628698702078 0.00947224548 0.017479770599759335 P04076 YHR018C ARG4 0.00042126270914282014 0.0001980478443428139 0.0002721367922786272 0.0003139471133186933 0.0012126507023262848 9.576474603701102e-05 9.576474603701102e-05 9.576474603701102e-05 9.576474603701102e-05 0.00027771776350733187 0.22732785019559854 0.48354349099223515 0.3518992975376968 0.3050346442899079 0.22901711348088352 P38707 YHR019C DED81 0.11333390091327876 0.10240898524021419 0.17221159224050414 0.19482767530591533 0.30636999502276085 0.0327575744136394 0.0327575744136394 0.0327575744136394 0.0327575744136394 0.09499696579955424 0.28903597378779855 0.31987012015402805 0.19021701145351133 0.1681361457616531 0.31007268121180315 P38708 YHR020W YHR020W 0.36443564243934534 0.3609754239697293 0.5674626526254488 0.55950644174913 0.7412921076661773 0.0690259894225793 0.0690259894225793 0.0690259894225793 0.0690259894225793 0.20017536932547994 0.18940515521630846 0.19122074479055862 0.1216397045747777 0.12336942753829631 0.27003574873567115 -P17423 YHR025W THR1 0.09342335155424462 0.08150826279042649 0.185717828355153 0.19392961095427225 0.2802853659084459 0.00619826952034838 0.00619826952034838 0.0062916814589142 0.00619826952034838 0.0179749816090103 0.06634604108320245 0.07604467704440383 0.03387763853711694 0.031961439461712246 0.06413100288254707 -P23968 YHR026W VMA16 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P17423 YHR025W THR1 0.09342335155424462 0.08150826279042649 0.18571782835514905 0.19392961095427225 0.2802853659084459 0.00619826952034838 0.00619826952034838 0.006291681458914067 0.00619826952034838 0.0179749816090103 0.06634604108320245 0.07604467704440383 0.03387763853711694 0.031961439461712246 0.06413100288254707 +P23968 YHR026W VMA16 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.061770206879045164 0.07953227647362911 0.07329440059762436 0.06048771278574579 0.046376574044575326 P07275 YHR037W PUT2 1.0 1.0 0.0 0.0 0.0 0.8057981178568774 0.8227669200686503 0.0 0.0 0.0 0.8057981178568774 0.8227669200686503 0.33992261680717006 0.31181060187625537 0.1526161196270574 -P48836 YHR039C-A VMA10 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.10252865553574501 0.17262936827131625 0.133435648 0.134097541272152 0.08316341204052694 -P16603 YHR042W NCP1 0.13802934574367473 0.13153932607105442 0.18482713759090616 0.1864318321917781 0.5502771678180667 0.011796476016492889 0.011914440776636153 0.011914440776188018 0.01191444077646804 0.03420978044767576 0.08546353641637448 0.09057702462456174 0.06446261588792918 0.06390775993775531 0.062168271642675604 +P48836 YHR039C-A VMA10 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1042597769587495 0.1342397544887476 0.12371106144418463 0.10209509992633911 0.07827740119871032 +P16603 YHR042W NCP1 0.09714507438407233 0.05601404780883193 0.08578750102668176 0.09897380503003654 0.3365624764562108 0.011796476016439919 0.011914440776614334 0.011914440776609702 0.011796476016474964 0.03420978044767576 0.1214315403146579 0.21270451329060605 0.1388831780156885 0.1191878599887614 0.1016446658221767 P38773 YHR043C DOG2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38774 YHR044C DOG1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38710 YHR046C INM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P00427 YHR051W COX6 0.33068913983845544 0.0 0.11401216875957708 0.7154161024568377 0.6412724733187571 0.0374507231179489 0.0 0.008413570743584902 0.039317806825147385 0.05430144531416071 0.11325053836435 0.09821610050317896 0.0737953749597291 0.05495795620216627 0.08467764885203345 -P38787 YHR063C PAN5 0.0002569720803211222 0.0001006611109913857 0.00012748315560707354 0.00012288429957679238 0.0006509323947418778 9.039989179810027e-06 9.039989179874405e-06 9.039989179613487e-06 9.039989198825216e-06 2.6215968621424482e-05 0.035178876897884424 0.08980617331600903 0.07091124420763784 0.07356504638882676 0.040274487540015926 +P00427 YHR051W COX6 0.20151667323204328 0.3295014362446161 0.5389014434584413 0.8953092692728256 0.8482724115955427 0.015900066212902846 0.02251828893316367 0.028987325708883942 0.03608091713913767 0.044050987537654615 0.07890198839574018 0.0683404879499417 0.05378966054137016 0.04029994816030751 0.05193023719208044 +P38787 YHR063C PAN5 0.0002569720810724181 0.00010066111098991522 0.00012748315561065849 0.0001228842992869484 0.0006509323947322048 9.039989206239773e-06 9.039989179742348e-06 9.039989179867699e-06 9.03998917750283e-06 2.621596862103491e-05 0.035178876897884424 0.08980617331600903 0.07091124420763784 0.07356504638882676 0.040274487540015926 P38790 YHR067W HTD2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38791 YHR068W DYS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.05374499733246283 0.039637917835018556 0.01920527752503292 0.017510806116205816 0.06109478378244026 -P38604 YHR072W ERG7 9.015052802428049e-05 1.000000000002672 0.9999999999650593 9.105203330307298e-05 0.0002614365312692394 0.09015052802428049 0.09105203330435774 0.09105203330093302 0.09105203330307299 0.26143653126923944 1000.0 0.09105203330411445 0.09105203330411445 1000.0 1000.0 -P38795 YHR074W QNS1 0.028328461182015985 0.019447865925229332 0.03006918149277795 0.03769619632928867 0.11462486129508809 0.002126132122853321 0.002126132122851008 0.002126132122847483 0.0021261321228489703 0.006165783156248991 0.07505286323858187 0.10932470076795517 0.07070801456162482 0.05640176807963613 0.053790975941736714 +P38604 YHR072W ERG7 9.015052802387569e-05 1.0000000000008407 1.0000000000004519 9.01505280241435e-05 0.0002614365312692394 0.09015052802387569 0.09105203330419098 0.0910520333041556 0.0901505280241435 0.26143653126923944 1000.0 0.09105203330411445 0.09105203330411445 1000.0 1000.0 +P38795 YHR074W QNS1 0.028328461181937336 0.01944786592522314 0.030069181492821947 0.0376961963295072 0.11462486129533225 0.002126132122847418 0.0021261321228503312 0.0021261321228505936 0.002126132122861296 0.006165783156262125 0.07505286323858187 0.10932470076795517 0.07070801456162482 0.05640176807963613 0.053790975941736714 P38714 YHR091C MSR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P32467 YHR092C HXT4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 0.013234534926651276 0.008069653146921993 1000.0 P32465 YHR094C HXT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38695 YHR096C HXT5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.06748210859817774 1000.0 1000.0 1000.0 -P38812 YHR100C GEP4 0.0 1.575522814032094e-05 1.0 1.0 0.0 0.0 0.01575522814032094 0.00024951417479531006 0.0002134004977453421 0.0 0.0003409590384756142 1000.0 0.00024951417479531006 0.0002134004977453421 1000.0 -P38715 YHR104W GRE3 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.12530338055354862 0.10459429129682594 0.0 0.21779944440000001 0.20002239774409913 0.12530338055354862 0.10459429129682594 0.06074481208314759 +P38812 YHR100C GEP4 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.00024951417479531006 0.0002134004977453421 0.0 0.0003409590384756142 1000.0 0.00024951417479531006 0.0002134004977453421 1000.0 +P38715 YHR104W GRE3 0.0 0.0 0.9999999986892188 0.0 0.0 0.0 0.0 0.1253033803893033 0.0 0.0 0.21779944440000001 0.20002239774409913 0.12530338055354862 0.10459429129682594 0.06074481208314759 P38816 YHR106W TRR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 0.0013609350869441144 0.0011475615791955648 1000.0 P38818 YHR109W CTM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P38824 YHR116W COX23 0.0 0.6617329222160458 1.0 1.0000000000000002 1.0000000000025877 0.0 0.05249767570998239 0.05949567719695513 0.04426028465611058 0.05768795196587046 0.09201569462072372 0.07933363136017992 0.05949567719695513 0.04426028465611057 0.057687951965721185 -P22140 YHR123W EPT1 3.587375382700057e-05 4.3129374578747855e-05 4.594635958819108e-05 4.5946359593776444e-05 0.0001277382512542401 0.03587375382700057 0.04312937457874785 0.045946359588191085 0.045946359593776444 0.12773825125424013 1000.0 1000.0 1000.0 1000.0 1000.0 +P38824 YHR116W COX23 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0077032399370141665 0.004347449036154341 0.0027053947374942686 0.0017738288833402103 0.0039429329563822 +P22140 YHR123W EPT1 4.000382142758492e-05 4.312937457873854e-05 4.594635959380297e-05 4.594635959376572e-05 0.0001277382512542403 0.04000382142758492 0.043129374578738534 0.04594635959380297 0.045946359593765716 0.1277382512542403 1000.0 1000.0 1000.0 1000.0 1000.0 P18562 YHR128W FUR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.13313338969230767 0.09857304258076863 0.06781615724715487 0.061893305176531487 0.09658202557805477 -P38840 YHR137W ARO9 0.03635985203451687 0.08110008302602532 2.7968769602770756e-06 2.7968769602770354e-06 8.11094318480354e-06 0.002799441427355047 0.0026360564914748212 0.0027968769602770755 0.002796876960277035 0.00811094318480354 0.0769926518044546 0.03250374590404428 1000.0 1000.0 1000.0 +P38840 YHR137W ARO9 0.036359852034518116 0.08110008302602534 2.796876960277067e-06 2.796876960277087e-06 8.110943184803507e-06 0.002799441427355143 0.002636056491474822 0.0027968769602770673 0.0027968769602770872 0.008110943184803506 0.0769926518044546 0.03250374590404428 1000.0 1000.0 1000.0 P06773 YHR144C DCD1 2.5461428134059083e-09 2.5461428134059083e-09 1.6974286520521003e-09 1.6974286520521003e-09 7.383814158877133e-09 2.546142813405908e-06 2.546142813405908e-06 1.6974286520521002e-06 1.6974286520521002e-06 7.383814158877133e-06 1000.0 1000.0 1000.0 1000.0 1000.0 P38857 YHR162W MPC2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P38858 YHR163W SOL3 1.0 0.1458416373205452 1.5829272298991042e-11 0.0 1.0 0.2164150595995762 0.016945102121130307 5.617132005862593e-13 0.0 0.039706114400000006 0.2164150595995762 0.1161883700186846 0.03548572479999999 0.03411327128591647 0.039706114400000006 +P38858 YHR163W SOL3 1.0 0.2398262407486252 0.0 0.0 1.0 0.21633752869964423 0.0278650200002914 0.0 0.0 0.039706114400000006 0.21633752869964423 0.1161883700186846 0.03548572479999999 0.03411327128591647 0.039706114400000006 P00925 YHR174W ENO2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.31957267449568 10.877312057510952 6.993199690197038 6.3554542528043205 7.041004241456458 -P38720 YHR183W GND1 0.08110239793599866 0.0053728818335372465 4.193272500717667e-13 0.0 0.05315272351550637 0.12820204011128064 0.007919738651312134 2.6253142140039826e-13 0.0 0.06996179648900354 1.580742904944072 1.4740206274177743 0.6260776549949156 0.5632370187517294 1.3162410477158977 -P29704 YHR190W ERG9 0.3137230092077632 0.2167921141503041 0.24935696947665809 0.2868467426082058 0.8670532972175832 0.03210944118268141 0.03243053559444926 0.032430535593229455 0.03243053559399166 0.09311737942935794 0.10234965316623275 0.1495927825675654 0.13005666399176072 0.11305875499617377 0.10739521979580287 -P38698 YHR201C PPX1 1.0 1.0 1.0 1.0 1.0 0.035253493823022924 0.06323603115175994 0.08659455077771722 0.11711174148354647 0.16361767872931243 0.035253493823022924 0.06323603115175994 0.08659455077771722 0.11711174148354647 0.16361767872931243 -P38891 YHR208W BAT1 0.0009796225370450789 0.0011545879561795046 0.0018082640075595198 0.01635968368955156 0.006913236990966942 0.000354405683513819 0.000354405683513819 0.0004011037030241869 0.003038092454227637 0.0022120979296245836 0.36177779717363784 0.3069542529150714 0.22181700312971828 0.18570606326380107 0.319980051676947 +P38720 YHR183W GND1 0.08107947447190308 0.008835323545440579 0.0 0.0 0.02321910001554624 0.1281658040080548 0.013023449155889356 0.0 0.0 0.0305619325314828 1.580742904944072 1.4740206274177743 0.6260776549949156 0.5632370187517294 1.3162410477158977 +P29704 YHR190W ERG9 0.3137230092063545 0.21679211414990704 0.24935696948548344 0.28400667585380096 0.8670532972175832 0.032109441182537224 0.03243053559438986 0.03243053559437725 0.03210944118263262 0.09311737942935794 0.10234965316623275 0.1495927825675654 0.13005666399176072 0.11305875499617377 0.10739521979580287 +P38698 YHR201C PPX1 1.0 1.0 1.0 1.0 1.0 0.035250426149960525 0.040445538265238515 0.1007670271897525 0.12862667749013468 0.16725781740352613 0.035250426149960525 0.040445538265238515 0.1007670271897525 0.12862667749013468 0.16725781740352613 +P38891 YHR208W BAT1 0.0009796225370450789 0.0011545879561795046 0.001808264007565192 0.015340255022100907 0.0069132369910066185 0.000354405683513819 0.000354405683513819 0.0004011037030254451 0.002848778369617113 0.002212097929637279 0.36177779717363784 0.3069542529150714 0.22181700312971828 0.18570606326380107 0.319980051676947 P38693 YHR215W PHO12 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P38697 YHR216W IMD2 1.4250964064106399e-05 0.0 0.0 2.8834757794702303e-05 6.808457429244931e-05 0.014250964064106399 0.0 0.0 0.028834757794702303 0.06808457429244931 1000.0 1000.0 1000.0 1000.0 1000.0 +P38697 YHR216W IMD2 1.4250964064106399e-05 0.0 0.0 2.8834757794700263e-05 6.808457429244931e-05 0.014250964064106399 0.0 0.0 0.028834757794700263 0.06808457429244931 1000.0 1000.0 1000.0 1000.0 1000.0 P40559 YIL002C INP51 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P40556 YIL006W YIA6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P39002 YIL009W FAA3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03164152749898282 0.04822788759047143 0.02785109364171628 0.026811252529302453 0.035150614805854484 P40553 YIL010W DOT5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.012846080015940847 0.02047752618061111 0.010098834436625794 0.00946329277858775 0.01035801112550867 -P40550 YIL013C PDR11 0.0 1.382614722154855e-06 6.903358503037355e-06 6.9033585000838025e-06 0.0 0.0 0.001382614722154855 0.006903358503037355 0.0069033585000838026 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P40550 YIL013C PDR11 0.0 1.3826147196160715e-06 6.903358503352429e-06 0.0 0.0 0.0 0.0013826147196160715 0.006903358503352429 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P40545 YIL020C HIS6 0.1587390723310457 0.1455523173346931 0.22321515815953905 0.2421256605048089 0.7056893280258565 0.0021440906329501146 0.0021440906329501146 0.0021440906329501146 0.0021440906329501146 0.006217862835555332 0.013507012492038988 0.014730721380545552 0.009605488492038987 0.00885528047080962 0.008811048415525293 P40544 YIL023C YKE4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P38626 YIL043C CBR1 0.0008843191159944521 0.0010675732014427026 0.0015994716683724423 0.0017893097489465573 0.003906822350399457 8.798620132894735e-05 8.886606334207525e-05 8.886606334183781e-05 8.886606334183781e-05 0.00025515998385280156 0.09949598480634829 0.08324118966454287 0.05555963578414885 0.04966499701583643 0.06531138633081499 +P38626 YIL043C CBR1 0.0008843191159904812 0.0010675732014407476 0.001599471668373165 0.0017715938108434385 0.003906822350399457 8.798620132855227e-05 8.88660633419125e-05 8.886606334187797e-05 8.798620132881367e-05 0.00025515998385280156 0.09949598480634829 0.08324118966454287 0.05555963578414885 0.04966499701583643 0.06531138633081499 P40527 YIL048W NEO1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 0.00907268011551895 0.009771864594945534 1000.0 P41277 YIL053W GPP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.27729377698693813 0.5824529253253343 0.49797549913050315 0.4913017637006523 0.08983647233845699 P21672 YIL066C RNR3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P40510 YIL074C SER33 0.0016025197440511622 0.0027656236394322624 0.010600237212738705 0.017138304321369077 0.004850428352103833 0.0004569591866111402 0.0006720287452740863 0.0016173256253861346 0.002082769631731367 0.0013192125855328565 0.28515042532702256 0.24299356416118967 0.15257447479029368 0.12152717052260785 0.27197857380176726 -P04801 YIL078W THS1 0.39853743451011786 0.4400441806459485 0.7212357535855565 0.81003355667152 0.9900990099009901 0.170313695031388 0.170313695031388 0.170313695031388 0.170313695031388 0.49390971559102514 0.42734679426221917 0.38703771694328865 0.23614150322510954 0.21025511057988502 0.4988488127469354 -P40506 YIL083C CAB2 0.00315836925328647 0.0040126772035037365 0.008843993960743464 0.011029642572470598 0.01597677939104631 7.619473425283324e-05 7.619473425337586e-05 7.619473425117669e-05 7.619473441310526e-05 0.0002209647293330091 0.024124707449437115 0.018988503283255666 0.008615421334454578 0.006908178022312642 0.013830367430424803 +P40510 YIL074C SER33 0.001601804217258386 0.002520455477831386 0.010600237212735612 0.01713986600994777 0.0048610644537918826 0.00045675515384184723 0.0006124544598678428 0.0016173256253856625 0.0020829594193255726 0.001322105377300783 0.28515042532702256 0.24299356416118967 0.15257447479029368 0.12152717052260785 0.27197857380176726 +P04801 YIL078W THS1 0.39853743451011786 0.4400441806459485 0.7212357535855565 0.81003355667152 0.99009900990099 0.170313695031388 0.170313695031388 0.170313695031388 0.170313695031388 0.49390971559102514 0.42734679426221917 0.38703771694328865 0.23614150322510954 0.21025511057988502 0.49884881274693543 +P40506 YIL083C CAB2 0.00315836926252043 0.0040126772034451185 0.008843993960992164 0.01102964254645527 0.015976779390808896 7.619473447559983e-05 7.61947342522628e-05 7.619473425331934e-05 7.619473423338673e-05 0.00022096472932972555 0.024124707449437115 0.018988503283255666 0.008615421334454578 0.006908178022312642 0.013830367430424803 P40495 YIL094C LYS12 0.04401379538972351 0.06765044249742533 0.11920392427631667 0.13242759768913373 0.17844115877296607 0.0215665264337018 0.0215665264337018 0.0215665264337018 0.0215665264337018 0.06254292665773521 0.48999469922417155 0.318793575289956 0.18092127893130627 0.1628552266297845 0.35049607998404514 P08019 YIL099W SGA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P40433 YIL107C PFK26 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P00425 YIL111W COX5B 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.11259551219653732 0.09764572913177663 0.0734144475044439 0.05461367518117759 0.08439566637762955 +P00425 YIL111W COX5B 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.07824227277370222 0.06776907918781845 0.053339914215773415 0.03996299207201063 0.051496037884454345 P07172 YIL116W HIS5 0.0002495579946869832 0.00020482324596914729 0.00028831396464133974 0.00029674262787277196 0.0011671990610518776 3.193370984930483e-05 3.193370984930483e-05 3.193370984930483e-05 3.193370984930483e-05 9.2607758562984e-05 0.1279610773013255 0.15590862110502357 0.11076019120000001 0.10761416409305498 0.07934187205353477 P40471 YIL124W AYR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.07490420333202313 0.1618005548075472 0.05660662651973089 0.053237433599999995 0.01917337191434602 -P20967 YIL125W KGD1 0.17402850309033807 0.42364357319386403 0.9999999999967675 1.0 0.4682899282441864 0.11077850190098587 0.16599658134362955 0.28466700799907974 0.21991874501300385 0.3119502125315729 0.63655378247712 0.3918307554914037 0.28466700799999994 0.21991874501300385 0.6661476015536014 -P40464 YIL134W FLX1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P40459 YIL145C PAN6 0.00016851509107239338 0.00016575586129568455 0.0004148399282097473 0.00048822387674778205 4.2020708422960455e-09 1.4489899456206855e-06 1.4489899456310045e-06 1.4489899455891828e-06 1.4489899486685673e-06 4.2020708422960455e-06 0.00859857675891001 0.008741711661382613 0.003492889297909045 0.0029678801420380345 1000.0 -P32191 YIL155C GUT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3576554087149968 0.7118350657756667 0.2194212308608608 0.1640122237043044 0.7647646715606546 -P27796 YIL160C POT1 0.0 0.0015060555749868056 0.535194786820948 0.3898774201538424 0.0 0.0 0.0001300499114549056 0.01255560601861967 0.006121448062538782 0.0 0.17771531142356248 0.0863513363084526 0.0234598810149102 0.01570095559810391 0.011522894070188342 +P20967 YIL125W KGD1 0.17405119785908946 0.38477907378222925 0.73945241539817 1.0 0.42198304525788666 0.110792948341877 0.15076827517737346 0.21049770664977013 0.22503116899927988 0.28110299349482604 0.63655378247712 0.3918307554914037 0.28466700799999994 0.22503116899927988 0.6661476015536014 +P40464 YIL134W FLX1 0.0 2.2694625903466746e-09 0.0 0.0 6.581441512005355e-09 0.0 2.2694625903466746e-06 0.0 0.0 6.581441512005355e-06 1000.0 1000.0 1000.0 1000.0 1000.0 +P40459 YIL145C PAN6 0.0001685150915650722 0.00016575586129326315 0.00041483992822141294 0.00048822387559622116 4.2020708422336025e-09 1.448989949857022e-06 1.4489899456098373e-06 1.4489899456299296e-06 1.4489899452508726e-06 4.202070842233602e-06 0.00859857675891001 0.008741711661382613 0.003492889297909045 0.0029678801420380345 1000.0 +P32191 YIL155C GUT2 0.0 0.0 0.0 0.0 2.2897918878852727e-06 0.0 0.0 0.0 0.0 1.7511519410808318e-06 1.3576554087149968 0.7118350657756667 0.2194212308608608 0.1640122237043044 0.7647646715606546 +P27796 YIL160C POT1 0.0 0.0 0.5302822364379307 0.06330654734499737 0.0 0.0 0.0 0.012440358171154332 0.0009939732889330667 0.0 0.17771531142356248 0.0863513363084526 0.0234598810149102 0.01570095559810391 0.011522894070188342 P00724 YIL162W SUC2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P40445 YIL166C SOA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P0CW40 YIL172C IMA3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 @@ -575,33 +575,33 @@ P32459 YIR032C DAL3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 P38998 YIR034C LYS1 2.0181081671017187e-05 2.0181081671017187e-05 2.0181081671017187e-05 2.0181081671017187e-05 5.852513684594983e-05 0.020181081671017186 0.020181081671017186 0.020181081671017186 0.020181081671017186 0.05852513684594983 1000.0 1000.0 1000.0 1000.0 1000.0 P40580 YIR036C IRC24 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04749824404378497 0.0572422202013607 0.032639753952797855 0.028161518573730837 0.0187789975714057 P40581 YIR037W HYR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.16909859813967157 0.23297866353181565 0.1378544155891665 0.11229464478130191 0.06206299383716986 -P47081 YJL003W COX16 0.0 0.6617329222160458 0.9999999999999999 1.0 1.0000000000025877 0.0 0.04267292880063645 0.04836128004974808 0.035977135183281474 0.04689186394638864 0.07479529582953735 0.06448663406035643 0.04836128004974809 0.035977135183281474 0.0468918639462673 +P47081 YJL003W COX16 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.006261606917273844 0.0035338399400591672 0.002199090063500798 0.0014418633324159915 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0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.052555256860823116 0.039569489111874016 0.03448695929438306 0.02941849503957455 0.03161352272969438 P14904 YKL103C APE1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3190305228309467 0.5886156649078186 0.4934244219721263 0.4669570823631343 0.12892120318992653 P14742 YKL104C GFA1 0.005911966655525284 0.005919539928724768 0.01051857498495406 0.011775177077559266 0.03528585662468161 0.0014788025586854462 0.0014788025586854462 0.0014788025586854462 0.0014788025586854462 0.004288527420187793 0.2501371615997474 0.2498171439826779 0.14058962937477265 0.12558643907816028 0.12153672407057481 Q01802 YKL106W AAT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.01078765144035405 1000.0 1000.0 1000.0 1000.0 -P32332 YKL120W OAC1 0.8859896223193935 0.8249432508299738 1.000000000003464 2.355518115019265e-11 0.0 0.02284632463430561 0.02284632463430561 0.02023390337329013 4.3548949568445976e-13 0.0 0.02578622148473615 0.02769441972077469 0.020233903373220043 0.018488055468887703 0.030348657668986128 +P32332 YKL120W OAC1 0.8859896227019136 0.8249432508299738 0.9999999999999851 0.0 0.0 0.022846324644169358 0.02284632463430561 0.02023390337321974 0.0 0.0 0.02578622148473615 0.02769441972077469 0.020233903373220043 0.018488055468887703 0.030348657668986128 P33401 YKL127W PGM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.042492740298935974 0.07471429325591737 0.04826173107205002 0.041808846531296046 0.05449600530081699 P36001 YKL132C RMA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P34163 YKL140W TGL1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0008583555340846362 0.0021012346709672115 0.0015186293452595753 0.0012136561207055484 1000.0 -P33421 YKL141W SDH3 0.23547383535260308 0.5018308400160303 0.8659128499283815 1.0000000000000757 0.5505499450671983 0.01946881288750317 0.02834036333367679 0.03366041670896563 0.035810811250920165 0.05036153248972182 0.08267930429871409 0.05647393717925247 0.038872753432114604 0.03581081125091745 0.0914749568880165 +P33421 YKL141W SDH3 0.5841869208449427 0.8720186098184978 0.9999999999999795 1.0000000000001303 0.7082884662434322 0.019471111171841988 0.02837705947861621 0.03374098672987372 0.03662949837795468 0.045477720088930876 0.03333027576803639 0.03254180491001519 0.03374098672987441 0.036629498377949904 0.06420790716829293 P36062 YKL146W AVT3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q00711 YKL148C SDH1 0.0 0.0 0.0 0.5154117368525274 0.0 0.0 0.0 0.0 0.0394702828540328 0.0 0.2715493271457588 0.18481262549792352 0.12727367721699903 0.0765801009792027 0.3009841611762416 +Q00711 YKL148C SDH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.10606996270225792 0.1035607403038543 0.10737700548542459 0.11656937835712543 0.20433465255220426 P36060 YKL150W MCR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6549198279745498 0.35275225636148055 0.22148864737012672 0.16267247590524592 0.3277657829040566 -P00950 YKL152C GPM1 0.006029558727876267 0.0064912223482335996 0.015299206641254587 0.03404271005768507 0.08640564308769318 0.021861767661444615 0.031605665164507524 0.04348695793010415 0.07558180679431493 0.12937442714207315 3.6257657729365502 4.868985141620993 2.842432222128485 2.220205344 1.4972914096683583 +P00950 YKL152C GPM1 0.00602991669453372 0.006756336336389593 0.015145269942286153 0.03424464056651326 0.08669146400627727 0.021863065564699063 0.03289650123367494 0.043049403296788184 0.07603013398913193 0.12980238434817262 3.6257657729365502 4.868985141620993 2.842432222128485 2.220205344 1.4972914096683583 P36051 YKL165C MCD4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P36029 YKL174C TPO5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P32895 YKL181W PRS1 0.032609343863313406 0.04019189948292066 0.06850678778759214 0.06278908572191355 0.13625471934425099 0.005383183193205855 0.005828306386229947 0.005390169784515459 0.00539016978453262 0.015631492375094008 0.1650810030330636 0.14501196662045435 0.07868081337031714 0.08584564853205749 0.11472257585148775 -P07149 YKL182W FAS1 0.15094710680368378 0.13297896958356042 0.31507998080960964 0.3345076354916091 0.8582207153786986 0.4734657489878894 0.4539338997765603 0.6897046708338819 0.5758604336390275 1.4876173928641878 3.1366334805188507 3.4135766068733178 2.188982838775286 1.7215165590845611 1.7333739051122317 +P32895 YKL181W PRS1 0.032609343863330816 0.040191899482917966 0.06850678778759701 0.06278908572172322 0.13625471934426148 0.005383183193208728 0.005828306386229556 0.005390169784515842 0.005390169784516281 0.015631492375095212 0.1650810030330636 0.14501196662045435 0.07868081337031714 0.08584564853205749 0.11472257585148775 +P07149 YKL182W FAS1 0.14085011244699633 0.12644534459377774 0.2973691028454214 0.252560332857466 0.8045469318450529 0.47346574897441956 0.45340731642373544 0.6911284292277324 0.45809496993083787 1.487617392864188 3.361486481969197 3.585796834832994 2.3241433713676543 1.813804110677058 1.84901257339042 P08432 YKL184W SPE1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P34230 YKL188C PXA2 0.0 6.356191394343596e-07 0.0003578750228809792 0.00015474942845170806 0.0 0.0 0.0006356191394343596 0.35787502288097917 0.15474942845170805 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P34230 YKL188C PXA2 0.0 0.0 0.0003564520598819716 1.640115234088699e-05 0.0 0.0 0.0 0.3564520598819716 0.01640115234088699 0.0 1000.0 0.0006356191394343595 1000.0 1000.0 1000.0 P32463 YKL192C ACP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.04553297030609097 0.03464902373168408 0.02276844603269527 0.018866006900130867 0.033718110997002726 P07236 YKL194C MST1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.007027938637497542 1000.0 0.004473912915048449 0.002749287136014483 1000.0 -P00937 YKL211C TRP3 0.0637152549291732 0.09884355551763699 0.11348160556547476 0.13076486956899466 0.25062016431424233 0.007400977766556154 0.011810009174746996 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0.012199494660816924 0.035378534516369096 0.07552099266259937 0.06837176372100746 0.047112741706430435 0.0403697807605661 0.06873027582690598 +P28272 YKL216W URA1 0.1615377953957767 0.17842884250576374 0.258942575170738 0.3021937308298093 0.5147445443907182 0.01219949466081693 0.012199494660816932 0.012199494660816925 0.012199494660816927 0.03537853451636911 0.07552099266259937 0.06837176372100746 0.047112741706430435 0.0403697807605661 0.06873027582690598 P36035 YKL217W JEN1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.004337545754717083 0.0023152642212520193 1000.0 1000.0 0.000714201443740311 P36007 YKL218C SRY1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.01394223668633965 0.05318303006925103 0.0350612313535431 0.03634054556540562 0.012760026648288703 P36033 YKL220C FRE2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q02207 YKR009C FOX2 0.0 3.359424206524875e-05 0.03992908884031345 0.03327038350355433 0.0 0.0 2.1892809649758407e-05 0.002113630755514312 0.0010304943364802942 0.0 1.0181590343896312 0.6516833928634819 0.052934610252872466 0.030973323056832355 0.07710158720257067 -P36126 YKR031C SPO14 3.8331851177069105e-08 4.6084632672306826e-08 4.9094639672676256e-08 4.909463967864433e-08 1.3649097499677676e-07 3.8331851177069104e-05 4.6084632672306825e-05 4.909463967267625e-05 4.909463967864433e-05 0.00013649097499677677 1000.0 1000.0 1000.0 1000.0 1000.0 -P19145 YKR039W GAP1 4.963657852654437e-05 0.10905910223327922 0.0013225776539924987 0.0018296386655559048 0.00013683811879820328 0.04963657852654437 0.2083645101214711 1.3225776539924987 1.829638665555905 0.1368381187982033 1000.0 1.9105650592627839 1000.0 1000.0 1000.0 +Q02207 YKR009C FOX2 0.0 0.0 0.03956257992523008 0.005402295694946578 0.0 0.0 0.0 0.0020942297489401707 0.00016732704980811504 0.0 1.0181590343896312 0.6516833928634819 0.052934610252872466 0.030973323056832355 0.07710158720257067 +P36126 YKR031C SPO14 4.274491420256368e-08 4.608463267229688e-08 4.909463967867268e-08 4.909463967863285e-08 1.3649097499677695e-07 4.2744914202563684e-05 4.608463267229688e-05 4.9094639678672676e-05 4.909463967863285e-05 0.00013649097499677696 1000.0 1000.0 1000.0 1000.0 1000.0 +P19145 YKR039W GAP1 4.944132797285151e-05 0.10905910223328867 0.0013225776539919725 0.001829787834677278 0.00013683811879838155 0.04944132797285151 0.20836451012148918 1.3225776539919725 1.829787834677278 0.13683811879838156 1000.0 1.9105650592627839 1000.0 1000.0 1000.0 P36136 YKR043C SHB17 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0671544054033568 0.08626849382538176 0.04852256454232127 0.043937653514862486 0.049973376845829795 P23500 YKR052C MRS4 0.0 0.0 0.0 0.0 2.439148983740731e-10 0.0 0.0 0.0 0.0 2.439148983740731e-07 1000.0 1000.0 1000.0 1000.0 1000.0 P23501 YKR053C YSR3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P36143 YKR058W GLG1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P33550 YKR061W KTR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 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0.00011370517607300536 0.00011370517607381511 0.00011370517607053329 0.00011370517631218296 0.00032974501061140617 1000.0 1000.0 1000.0 1000.0 1000.0 +P36024 YKR072C SIS2 0.005007347964173927 0.013981170155952348 0.017103776915961152 0.011962653245345095 0.04766558988263691 0.00011370517640543928 0.00011370517607215409 0.00011370517607373076 0.00011370517604398539 0.0003297450106065062 0.022707664260396068 0.00813273673117734 0.00664795715194471 0.009505013119746684 0.0069178837693692746 P36156 YKR076W ECM4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.035418944746011545 0.030885935758253148 0.01068441791234117 0.009154992465092842 0.0053508774357737725 -Q02046 YKR080W MTD1 0.9290026593326662 1.0 0.9999999999991344 0.9999999999997936 1.0 0.08307682830901496 0.21829984435520183 1.1624500859724984 1.592476469433179 0.23437891316230705 0.08942582399999999 0.21829984435520183 1.1624500859735047 1.5924764694335076 0.23437891316230705 +Q02046 YKR080W MTD1 0.9290026593353375 1.0 1.0000000000000109 1.0000000000000526 1.0 0.08307682830925384 0.2182998443552095 1.162450085972055 1.5926029762170635 0.2343789131624736 0.08942582399999999 0.2182998443552095 1.1624500859720424 1.5926029762169795 0.2343789131624736 P36165 YKR089C TGL4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P32901 YKR093W PTR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P10963 YKR097W PCK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.11896520591620365 0.08446896962038783 0.01208784457156934 1000.0 0.05842696028300804 @@ -713,171 +713,171 @@ P54861 YLL001W DNM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.08997604195920954 Q07804 YLL012W YEH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 0.001251404928652152 1000.0 1000.0 P14772 YLL015W BPT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P04802 YLL018C DPS1 0.023253818091540243 0.027571055733962783 0.050243053172660576 0.058371191038690554 0.10450243819399993 0.017669794418287373 0.017669794418287373 0.017669794418287373 0.017669794418287373 0.051242403813033376 0.7598663732867016 0.6408820390769888 0.35168631885417095 0.30271430313243375 0.4903464904608847 -Q3E731 YLL018C-A COX19 0.0 0.6617329222160457 0.9999999999999998 1.0 1.0000000000025877 0.0 0.0336636267905852 0.03815102755931324 0.02838147944948077 0.03699184123923037 0.05900417419812547 0.05087192379344024 0.038151027559313246 0.02838147944948077 0.03699184123913465 +Q3E731 YLL018C-A COX19 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.004939628103738441 0.0027877596458305786 0.0017348082087928081 0.0011374506149378124 0.0025283676221633175 Q07824 YLL028W TPO1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q07830 YLL031C GPI13 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P21801 YLL041C SDH2 0.23547383535260305 0.5018308400160303 0.8659128499283812 1.0000000000000755 0.5505499450671982 0.026670368062448265 0.038823523832716283 0.04611147623385625 0.04905730627725971 0.06899037016026736 0.11326255429827922 0.07736376630714072 0.05325186736479322 0.049057306277256005 0.12531173743346144 +P21801 YLL041C SDH2 0.5841869208449426 0.8720186098184978 0.9999999999999792 1.0000000000001303 0.7082884662434321 0.026673516487038022 0.03887379395949096 0.04622184927636452 0.050178827508788645 0.06230002519523605 0.045659215458741534 0.04457908755821412 0.046221849276365475 0.05017882750878211 0.08795854819669492 P23900 YLL043W FPS1 0.0 0.0 4.0244717233923345e-05 7.042267567840531e-05 0.0 0.0 0.0 0.040244717233923345 0.07042267567840531 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P32386 YLL048C YBT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q12473 YLL051C FRE6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P0CD90 YLL052C AQY2 0.0018697398088155417 0.002416642993239275 0.002761600854647189 0.0034766606460484386 0.00570640575978424 1.8697398088155417 2.4166429932392752 2.761600854647189 3.4766606460484386 5.70640575978424 1000.0 1000.0 1000.0 1000.0 1000.0 -P0CD98 YLL053C YLL053C 1.1750670961844097e-06 1.4127294620555113e-06 1.5203261782558492e-06 1.520326178432245e-06 4.1841457878973396e-06 0.0011750670961844097 0.0014127294620555114 0.0015203261782558493 0.001520326178432245 0.00418414578789734 1000.0 1000.0 1000.0 1000.0 1000.0 +P0CD90 YLL052C AQY2 0.0018697785849727225 0.002416862950846772 0.0027615972830154056 0.0034788878632691822 0.005512589505285209 1.8697785849727224 2.416862950846772 2.7615972830154054 3.478887863269182 5.5125895052852085 1000.0 1000.0 1000.0 1000.0 1000.0 +P0CD98 YLL053C YLL053C 1.3103500265780468e-06 1.4127294620552066e-06 1.5203261784403696e-06 1.5050015565098e-06 4.184145787897345e-06 0.001310350026578047 0.0014127294620552065 0.0015203261784403697 0.0015050015565098 0.004184145787897345 1000.0 1000.0 1000.0 1000.0 1000.0 Q12358 YLL057C JLP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q12198 YLL058W YLL058W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q12372 YLL061W MMP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q12525 YLL062C MHT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q07923 YLR011W LOT6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.007103022546297676 0.006990983122715958 0.003342944851620657 0.00312319956 1000.0 -Q07938 YLR017W MEU1 0.009379815145923091 1.0 1.0 1.0 1.0000000000258626 0.0007684647683201542 0.09863639314388886 0.053757615271766625 0.04973791082059297 0.07414570996053742 0.08192749605029957 0.09863639314388886 0.053757615271766625 0.04973791082059297 0.07414570995861981 -Q07950 YLR020C YEH2 0.0 0.0 6.586426777889951e-08 6.586426775071996e-08 0.0 0.0 0.0 6.586426777889951e-05 6.586426775071996e-05 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P23542 YLR027C AAT2 0.004002082905146172 0.005212776407913715 0.006242957959417647 0.007395858378389265 0.01489099388875098 0.0025362233605094545 0.0025368063219826913 0.0025429911557663244 0.0025362233605110284 0.007355047745474833 0.6337258424227525 0.4866516657287408 0.40733754292388963 0.342924814234124 0.4939259125632316 +Q07938 YLR017W MEU1 0.009379815173346372 1.0 1.0 1.0 1.0000000000027647 0.0007684647705668748 0.09863639314388886 0.053757615271766625 0.04973791082059297 0.0741457099588248 0.08192749605029957 0.09863639314388886 0.053757615271766625 0.04973791082059297 0.07414570995861981 +Q07950 YLR020C YEH2 0.0 0.0 6.58642677819056e-08 0.0 0.0 0.0 0.0 6.586426778190561e-05 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P23542 YLR027C AAT2 0.004002082905150111 0.005211578504947358 0.006242957959417783 0.007406789888430492 0.01489099388875121 0.002536223360511951 0.0025362233605087325 0.0025429911557663795 0.0025399720465612147 0.007355047745474946 0.6337258424227525 0.4866516657287408 0.40733754292388963 0.342924814234124 0.4939259125632316 P54113 YLR028C ADE16 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.30212844309303827 0.32566304918664934 0.22843549879645297 0.197100138796453 0.15223805916800803 -Q01519 YLR038C COX12 0.33068913983845544 0.0 0.11401216875957708 0.7154161024568377 0.6412724733187573 0.02113756647898073 0.0 0.004748704326963962 0.022191367385799944 0.0306482843233194 0.06391974798236984 0.05543415936599675 0.04165085515545084 0.031018825701003547 0.04779292047997367 +Q01519 YLR038C COX12 0.20151667323204328 0.3295014362446161 0.5389014434584413 0.8953092692728255 0.8482724115955427 0.008974158003222987 0.012709549768066312 0.016360739478638912 0.020364434145881648 0.024862822397564488 0.044533079369017695 0.038572061818361744 0.03035942782717859 0.022745697877585628 0.02930995050375293 P22217 YLR043C TRX1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.15665326113533795 0.17027430939612867 0.09878967003388142 0.07641986063052421 0.12086536408169335 -P06169 YLR044C PDC1 0.001982213574213625 0.026207690935848262 0.03783361558955786 0.05877169997035325 0.14667906840716577 0.011210757589008703 0.14729237302827758 0.21371203364972755 0.3743235240245084 0.590234762467691 5.655675924556306 5.6201965060112675 5.648734077340269 6.369111735977211 4.023987668296754 +P06169 YLR044C PDC1 0.0019822135742100485 0.015442205116489402 0.019330211193642605 0.0418276121724141 0.12182783275822372 0.011210757588988476 0.08678822724080305 0.10919122269171332 0.26640473557522587 0.4902336966744115 5.655675924556306 5.6201965060112675 5.648734077340269 6.369111735977211 4.023987668296754 Q12209 YLR047C FRE8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P32353 YLR056W ERG3 0.0 0.5111076869497188 0.26219112153413066 0.23526110641076392 0.0 0.0 0.012455427258248707 0.008262677326098452 0.0060787201034893205 0.0 0.019936284265301626 0.024369477462924626 0.031513947832222305 0.02583818547922633 0.01737966731026596 +P32353 YLR056W ERG3 0.0 0.0 0.2621911211796031 0.0 0.0 0.0 0.0 0.008262677314925889 0.0 0.0 0.019936284265301626 0.024369477462924626 0.031513947832222305 0.02583818547922633 0.01737966731026596 Q12205 YLR057W MNL2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P37291 YLR058C SHM2 0.0006749512125277232 0.0013844751931630435 0.008277237240734274 0.012122046044749578 0.0018465885742567894 0.0010604907283487815 0.001950836368240451 0.008192520750872548 0.011033576268075752 0.0030349416464484735 1.5712109389020803 1.4090800455466952 0.9897651248360001 0.910207421036379 1.6435397081723901 -P15624 YLR060W FRS1 0.0027702858255817956 0.003334161433446808 0.005414299903736412 0.005981114685389914 0.008327478717740403 0.001035213719593679 0.001035213719593679 0.001035213719593679 0.001035213719593679 0.0030021197868216687 0.3736848053851161 0.3104869815866984 0.19119992205811823 0.17308039956538512 0.3605076504640135 +P37291 YLR058C SHM2 0.0006745957701398568 0.001384475193163082 0.008277237240731318 0.012122964288669666 0.001846588574257456 0.0010599322533808163 0.0019508363682405052 0.008192520750869622 0.011034412060506137 0.003034941646449569 1.5712109389020803 1.4090800455466952 0.9897651248360001 0.910207421036379 1.6435397081723901 +P15624 YLR060W FRS1 0.0030475295514374745 0.0035282737338931903 0.00572960947506084 0.0061698265191195 0.009320083434642634 0.001035213719593679 0.001035213719593679 0.001035213719593679 0.001035213719593679 0.0030021197868216687 0.3396894770406358 0.29340516005015205 0.18067788460969875 0.16778651982931525 0.32211297333056343 Q07993 YLR070C XYL2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P13181 YLR081W GAL2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P52893 YLR089C ALT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.07074261572014058 0.10302046946267392 0.04127973924341285 0.029483960128110363 0.028007000596254245 Q12325 YLR092W SUL2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q12452 YLR100W ERG27 0.9900990099054361 1.000000000002672 1.0 1.0 0.9900990099009901 0.11148828036743325 0.11260316317090283 0.11260316317060194 0.11260316317060194 0.32331601306410457 0.11260316317060194 0.11260316317060194 0.11260316317060194 0.11260316317060194 0.32654917319474563 -P38013 YLR109W AHP1 0.0 4.2822124240548226e-05 0.00462553274551007 0.0019479250705298399 0.0 0.0 4.3290597444804153e-05 0.004100816927151347 0.0018784397678724728 0.0 0.7622041785484704 1.010939980502236 0.886560998002218 0.964328554671527 0.17784701825037716 +Q12452 YLR100W ERG27 0.9900990099009901 1.0000000000008407 1.0000000000004519 0.9900990099039315 0.9900990099009901 0.11148828036693262 0.1126031631706966 0.11260316317065283 0.11148828036726383 0.32331601306410457 0.11260316317060194 0.11260316317060194 0.11260316317060194 0.11260316317060194 0.32654917319474563 +P38013 YLR109W AHP1 0.0 0.0 0.004609049820925187 0.0 0.0 0.0 0.0 0.0040862038090813775 0.0 0.0 0.7622041785484704 1.010939980502236 0.886560998002218 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1000.0 P09368 YLR142W PUT1 2.982920763816391e-05 1.0 0.0 0.0 0.0 0.02982920763816391 0.03045736239967182 0.0 0.0 0.0 1000.0 0.03045736239967182 0.019524865472422232 0.02154645425765747 1000.0 -Q12455 YLR146C SPE4 0.0035107911395330783 0.6177738632187691 3.933298532798979e-07 3.639187688406843e-07 0.25897235071226254 5.622647750390135e-06 0.0007216956676223701 0.0003933298532798979 0.0003639187688406843 0.0005425039982275546 0.0016015329670502488 0.0011682198140629326 1000.0 1000.0 0.0020948336636536025 +Q12455 YLR146C SPE4 0.0035107911497973955 0.6177738632187691 3.933298532798979e-07 3.639187688406843e-07 0.25897235070628083 5.622647766828778e-06 0.0007216956676223701 0.0003933298532798979 0.0003639187688406843 0.0005425039982150238 0.0016015329670502488 0.0011682198140629326 1000.0 1000.0 0.0020948336636536025 Q12524 YLR151C PCD1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P52910 YLR153C ACS2 0.05885952727240987 0.1023124735316506 0.059901522174142637 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0.8659128499283812 1.0 0.5505499450671983 0.01643750778140108 0.02392775283818497 0.02841947091360556 0.019763443349738837 0.04252021358294802 0.06980609016193769 0.0476809134277611 0.03282024388015042 0.019763443349738837 0.07723225470081219 +Q06236 YLR164W SHH4 0.5841869208449426 0.8720186098184977 0.9999999999999795 1.0000000000001303 0.7082884662434322 0.01643944822157694 0.023958735372737773 0.028487496136986 0.030926264898407267 0.038396813517172376 0.02814073310268507 0.027475027600299212 0.028487496136986586 0.030926264898403236 0.05421069994379345 P32469 YLR172C DPH5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.05342202569994703 0.041694654594661824 0.024534129530720976 0.02054682730155266 0.040813148219761494 -P41939 YLR174W IDP2 0.051424516650048054 0.1805358756803663 0.9999999999996532 0.9999999999999757 0.7634664001567036 0.03997454921143931 0.06439356180386345 0.07879530613975723 0.0822147710072712 0.12690160763112812 0.7773441894159632 0.35668014216670396 0.07879530613978455 0.0822147710072732 0.16621767193039694 +P41939 YLR174W IDP2 0.05143087716408938 0.16446108349646404 1.0 1.0 0.7002678051412016 0.03997949352007103 0.05866000264240897 0.07576568639999999 0.04064097298936423 0.11639688429837937 0.7773441894159632 0.35668014216670396 0.07576568639999999 0.04064097298936423 0.16621767193039694 P10659 YLR180W SAM1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.23554778916226426 0.21750719880220298 0.204527145523821 0.19662832855250306 0.3827414770214113 Q06321 YLR189C ATG26 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q05779 YLR201C COQ9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0051930459918978515 1000.0 0.0013901969030093457 0.0024815226433217838 1000.0 -Q05788 YLR209C PNP1 7.538728468714166e-05 0.009124676354627832 0.007186634369201227 0.007301989595861598 0.013145889165146871 4.058118328521237e-06 0.0005208802945533085 0.00028388388489016935 0.000262656579513236 0.00039154958948842833 0.05383027582652018 0.057084796688611286 0.039501645736531636 0.035970549678966485 0.029784945283619677 +Q05779 YLR201C COQ9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.007782775579648125 0.005387155971232533 0.0025467821939910125 0.002987524240701979 0.004329804047754202 +Q05788 YLR209C PNP1 7.538728490754755e-05 0.009124676354627832 0.007186634369201227 0.007301989595861598 0.013145889164843225 4.058118340385747e-06 0.0005208802945533085 0.00028388388489016935 0.000262656579513236 0.00039154958947938424 0.05383027582652018 0.057084796688611286 0.039501645736531636 0.035970549678966485 0.029784945283619677 Q05789 YLR211C ATG38 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P32791 YLR214W FRE1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q05979 YLR231C BNA5 0.03888548271031182 0.08469487146410953 0.048570003545466096 0.05623953690989616 0.27139870617750483 0.0024584463386750155 0.0060764185990873475 0.0025152335247157803 0.0025155668894167402 0.00729417722166838 0.06322272908349609 0.07174482343552883 0.05178573895637634 0.04472950930316231 0.026876241690325955 +Q05979 YLR231C BNA5 0.03888548271020383 0.08469487146410185 0.048570003545517194 0.056232084006981424 0.2713987061779178 0.002458446338668188 0.006076418599086796 0.0025152335247184267 0.00251523352472648 0.0072941772216794775 0.06322272908349609 0.07174482343552883 0.05178573895637634 0.04472950930316231 0.026876241690325955 Q05998 YLR237W THI7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 0.00032876625600000004 1000.0 1000.0 P22543 YLR240W VPS34 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q01662 YLR244C MAP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.10249161519622078 0.08373889807922572 0.0719849472211161 0.07012842870483979 0.1227856552633456 Q06549 YLR245C CDD1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P27472 YLR258W GSY2 0.5575790865566087 0.7840198986438651 1.0 1.0 1.0 0.0646094836601129 0.0646094836601129 0.054666112274385295 0.0493137773217936 0.025410143732918604 0.11587501256389639 0.08240796409870364 0.054666112274385295 0.0493137773217936 0.025410143732918604 Q06147 YLR260W LCB5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q05871 YLR284C ECI1 0.0 0.0034217854605857988 3.812525439184787e-07 7.719202256039778e-07 0.0 0.0 7.126048522191632e-05 0.0003812525439184787 0.0007719202256039777 0.0 0.016484513853288137 0.02082552691942199 1000.0 1000.0 1000.0 +Q05871 YLR284C ECI1 0.0 0.0 2.661286785745291e-07 4.5823471881495084e-07 0.0 0.0 0.0 0.0002661286785745291 0.00045823471881495083 0.0 0.016484513853288137 0.02082552691942199 1000.0 1000.0 1000.0 Q05874 YLR285W NNT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.010053061655998235 0.01036709684649056 0.005886192854190846 0.007124180458347798 0.006975559512033822 P29029 YLR286C CTS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.02309287805853606 0.02205684458033371 0.012895799455419538 0.009870711615768964 0.027275995942936723 -Q12349 YLR295C ATP14 1.0 1.0 1.0 1.0000000000000002 1.0000000000003733 0.30878127663019195 0.39338716705674254 0.5412300143390169 0.6676160085569726 0.9055800290705364 0.30878127663019195 0.39338716705674254 0.5412300143390169 0.6676160085569725 0.9055800290701984 +Q12349 YLR295C ATP14 0.18606678454578032 0.2792293484145761 0.5299665414308694 0.8820433979562666 0.5896040184072173 0.016259623443906565 0.022123615775803143 0.028724182338356795 0.036986897608819035 0.0441823152392338 0.08738595383157174 0.07923098306613484 0.05419999206139257 0.0419331947776258 0.0749355734694446 Q05902 YLR299W ECM38 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.00613333693192224 0.015751848454095444 0.010311175830871348 1000.0 1000.0 P23776 YLR300W EXG1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.003613940801307763 0.0051420428638993 0.003063488832671199 0.002893380993952715 0.0021238816961732954 -P06106 YLR303W MET17 0.00020325141935372904 0.0003135964540582285 0.00044397728157503306 0.0004883392865202095 0.0008354533247533468 0.0016681143322862374 0.0016681143322862574 0.0016681143322861797 0.001668114332291828 0.004837531563630084 8.207147274003194 5.319302277494893 3.7572065092350115 3.4158921437151144 5.790307393962771 -P19414 YLR304C ACO1 0.1645379045779371 0.19089263178052962 0.256638795505141 0.4422608525134906 0.3368750600124071 0.2933146920631292 0.4210649237278362 0.5152262318134487 0.545593234569808 0.8297834009920173 1.7826572716816997 2.2057683410847257 2.0075929315337193 1.2336457804688137 2.4631784880764296 +P06106 YLR303W MET17 0.00020325141935467587 0.00031359645405822106 0.00044397728157505317 0.0004883392865183744 0.0008354533247533266 0.0016681143322940081 0.001668114332286218 0.0016681143322862554 0.0016681143322855596 0.004837531563629967 8.207147274003194 5.319302277494893 3.7572065092350115 3.4158921437151144 5.790307393962771 +P19414 YLR304C ACO1 0.16455604032041388 0.18957329230413072 0.257203338803377 0.45159861698927395 0.30898905155915063 0.29334702187633277 0.4181547664796522 0.5163596049485321 0.5571127283143698 0.7610951848516386 1.7826572716816997 2.2057683410847257 2.0075929315337193 1.2336457804688137 2.4631784880764296 P37297 YLR305C STT4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q06702 YLR307W CDA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q06703 YLR308W CDA2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q06178 YLR328W NMA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38631 YLR342W FKS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.12206863376572352 0.1892610420808632 0.17497787964940098 0.0997796702339961 0.2108557533225419 Q06137 YLR345W YLR345W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.026372654048730883 1000.0 1000.0 0.01281918893263894 1000.0 -Q06143 YLR348C DIC1 0.0 0.0 0.0 1.506628310754014e-06 0.0 0.0 0.0 0.0 0.001506628310754014 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q06144 YLR350W ORM2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q06143 YLR348C DIC1 4.062992432212611e-15 0.0 0.0 1.581259344490812e-06 0.0 4.062992432212611e-12 0.0 0.0 0.0015812593444908122 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q06144 YLR350W ORM2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0059520590279434635 0.006013913695867318 0.004383206436864032 0.004305299267031074 0.005373726522030329 P49954 YLR351C NIT3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.05182341996081049 0.08872481040160089 0.06272993184028344 0.0580601092460735 0.039514009651916884 -P15019 YLR354C TAL1 0.014554885169930552 0.001068750477171236 0.000645422815544641 0.004061638712131651 0.013497052698647984 0.014293031920029384 0.0011635672364284887 0.00035369897487979 0.0018392345682607678 0.007587662778967636 0.9820092534675477 1.0887173959521528 0.5480112669728302 0.4528306672789937 0.5621718273151368 -P06168 YLR355C ILV5 0.013773842394622371 0.021571028258881783 0.039253443672289584 0.15121681393778555 0.06751982762493533 0.06349501004238967 0.07043986489974892 0.0634950100423894 0.19952017524050633 0.18413552912217102 4.6098255100682435 3.2654848 1.6175653421004896 1.3194311534866356 2.7271326897488857 -Q05911 YLR359W ADE13 0.0013994493063492124 0.001800461953427781 0.002750023760952845 0.0031271009277198877 0.005066683304462432 0.0010800231075783306 0.001080023107578272 0.0010800231075777334 0.0010800231075816648 0.003132067011975215 0.7717486461841344 0.599858889282324 0.39273228213981703 0.34537519976023257 0.618169090856079 +P15019 YLR354C TAL1 0.014550755967746314 0.0010687504771715508 0.00020995340668220218 0.00024404834727490243 0.00565434760475982 0.014288977005275023 0.0011635672364288315 0.0001150568324011755 0.00011051257594482964 0.003178714925242795 0.9820092534675477 1.0887173959521528 0.5480112669728302 0.4528306672789937 0.5621718273151368 +P06168 YLR355C ILV5 0.013773842394630488 0.019444282834325116 0.0392534436722898 0.14263899697974874 0.06751982762521344 0.06349501004242708 0.06349501004238958 0.06349501004238975 0.18820233631716662 0.18413552912292946 4.6098255100682435 3.2654848 1.6175653421004896 1.3194311534866356 2.7271326897488857 +Q05911 YLR359W ADE13 0.0013994493063554379 0.0018004619534274333 0.00275002376095317 0.003127100927708919 0.005066683304462921 0.0010800231075831352 0.0010800231075780635 0.0010800231075778612 0.0010800231075778766 0.0031320670119755175 0.7717486461841344 0.599858889282324 0.39273228213981703 0.34537519976023257 0.618169090856079 Q05919 YLR360W VPS38 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P40319 YLR372W ELO3 0.0 0.0 7.318074863066614e-07 0.08224204786339544 0.0 0.0 0.0 0.0007318074863066614 0.0006357042189426906 0.0 1000.0 1000.0 1000.0 0.007729673998373671 1000.0 +P40319 YLR372W ELO3 0.0 0.0 7.318074862175087e-07 0.0 0.0 0.0 0.0 0.0007318074862175088 0.0 0.0 1000.0 1000.0 1000.0 0.007729673998373671 1000.0 P09201 YLR377C FBP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1172491988260228 1000.0 1000.0 1000.0 1000.0 P11325 YLR382C NAM2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.004980640548907561 0.0035766216543847585 0.0021544557177134954 0.012907661638816978 Q06708 YLR386W VAC14 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0013482143065646846 0.0018894657193096285 0.001890272856882688 0.0014721701509663072 0.0008402762920557134 -P04039 YLR395C COX8 0.33068913983845544 0.0 0.1140121687595771 0.7154161024568377 0.6412724733187573 0.019235012732762707 0.0 0.004321282125078465 0.020193962944965275 0.027889688237413765 0.0581664482303809 0.050444631944517065 0.0379019377676339 0.02822687786257035 0.04349116701217057 +P04039 YLR395C COX8 0.20151667323204328 0.3295014362446161 0.5389014434584414 0.8953092692728255 0.8482724115955428 0.008166410434686059 0.01156558641031535 0.014888139204764691 0.01853146862866447 0.022624965171138836 0.040524738244773255 0.0351002609947025 0.027626831186828738 0.020698399161795587 0.026671815400176477 Q06685 YLR410W VIP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.08298690799680905 0.07658263447908317 0.054238284348903085 0.04299165397268529 0.05962454903680299 -P20051 YLR420W URA4 0.045068302573461796 0.03783449043243341 0.05653553650307576 0.06440536197363919 0.2497085723874901 0.0019280847311656942 0.0019280847311599887 0.0019280847311599913 0.0019280847311599907 0.0055914457203639755 0.04278139226616969 0.050961033414821645 0.034103943296887186 0.029936711355634433 0.022391885336188383 +P20051 YLR420W URA4 0.045068302573328514 0.037834490432433476 0.056535536503075745 0.06440536197363922 0.24970857238749025 0.001928084731159992 0.0019280847311599922 0.0019280847311599909 0.0019280847311599913 0.005591445720363978 0.04278139226616969 0.050961033414821645 0.034103943296887186 0.029936711355634433 0.022391885336188383 P50095 YLR432W IMD3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P07991 YLR438W CAR2 0.0 0.0 0.08632008862190506 0.10387453029484489 0.5697411026824332 0.0 0.0 0.004175463725398881 0.004433353491376152 0.012206868565109486 0.2511289931806227 0.17035855568530947 0.0483718656 0.04267988965911282 0.021425290377748027 Q06204 YLR446W YLR446W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P32366 YLR447C VMA6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.09445715661662814 0.17758534737390316 0.12906963596123522 0.15676452291529966 0.07677398496929871 +P32366 YLR447C VMA6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.10877581438856816 0.1400543818889262 0.12906963596123522 0.10651737384747789 0.08166800574472016 P12684 YLR450W HMG2 0.0 0.0 0.0 0.0 3.947254857535463e-05 0.0 0.0 0.0 0.0 0.03947254857535463 1000.0 1000.0 1000.0 1000.0 1000.0 -P50107 YML004C GLO1 0.0 0.01695549983892768 0.0 0.0 0.0 0.0 0.00047964370804847866 0.0 0.0 0.0 0.0392962581192096 0.028288385043493524 0.014013444431060883 0.00950463115657444 0.010819435281046912 -P25087 YML008C ERG6 0.0 0.29868613974496017 0.3864562355435158 0.32397096333054526 0.0 0.0 0.5474353741714318 0.363157502338985 0.26716919021250607 0.0 1.5017026367912025 1.8328114409288352 0.9397118455812642 0.8246701724929443 0.37637974492300796 +P50107 YML004C GLO1 0.0 0.0 0.018857465433001264 0.025992705111840115 0.0 0.0 0.0 0.0002642580439560147 0.0002470510748496473 0.0 0.0392962581192096 0.028288385043493524 0.014013444431060883 0.00950463115657444 0.010819435281046912 +P25087 YML008C ERG6 0.0 0.0 0.38645623502096044 0.0 0.0 0.0 0.0 0.3631575018479335 0.0 0.0 1.5017026367912025 1.8328114409288352 0.9397118455812642 0.8246701724929443 0.37637974492300796 P49435 YML022W APT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.08043803811759712 0.08032371954761552 0.04298168648324848 0.03723544763872615 0.04057669706785317 P15274 YML035C AMD1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.02381789864493858 0.025777240644938578 0.020350477248587535 0.015616081244193798 0.022394857647329736 -P32796 YML042W CAT2 0.0 2.9038140919039417e-08 1.2025691736209146e-06 1.312644527229781e-06 0.0 0.0 2.9038140919039416e-05 0.0012025691736209146 0.001312644527229781 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P00175 YML054C CYB2 0.0 0.0 0.05210857247849774 0.04814670632337203 0.0 0.0 0.0 0.001259714161262884 0.0009961535394166284 0.0 0.5228146320573119 0.17528859964358529 0.024174796993003345 0.02068996231488969 0.42411602132768444 -P50094 YML056C IMD4 1.0 3.056472782331684e-05 3.056472782331702e-05 1.0 1.0 0.016348048760320092 0.03056472782331684 0.03056472782331702 0.0017993407531882084 0.020716934415756717 0.016348048760320092 1000.0 1000.0 0.0017993407531882084 0.020716934415756717 +P32796 YML042W CAT2 0.0 0.0 1.1721432907945625e-06 2.2593309963910182e-07 0.0 0.0 0.0 0.0011721432907945625 0.0002259330996391018 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P00175 YML054C CYB2 0.0 0.0 0.05210857247307924 0.0 0.0 0.0 0.0 0.0012597141611318929 0.0 0.0 0.5228146320573119 0.17528859964358529 0.024174796993003345 0.02068996231488969 0.42411602132768444 +P50094 YML056C IMD4 1.0 3.056472782331702e-05 3.056472782331702e-05 1.0 1.0 0.016348048760320092 0.03056472782331702 0.03056472782331702 0.0017993407531882084 0.020716934415756717 0.016348048760320092 1000.0 1000.0 0.0017993407531882084 0.020716934415756717 Q04958 YML059C NTE1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P54838 YML070W DAK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.19406325682123984 0.20086677049121482 0.13719345892098436 0.11859727139298055 0.08993968122039482 -P12683 YML075C HMG1 0.30940162136537835 0.3092136107661825 0.4946567325829764 0.5077488847530589 1.0 0.03416658657310475 0.03450825243877305 0.034508252437475094 0.03450825243828613 0.0596344142062684 0.11042794935051994 0.11160004358562046 0.06976201912239513 0.06796322645803357 0.0596344142062684 -P81450 YML081C-A ATP18 1.0 0.9999999999999999 1.0 1.0 1.0000000000003733 0.14617279006955858 0.18622404963728012 0.25621081086490266 0.3160401943112282 0.4286890737842403 0.14617279006955858 0.18622404963728015 0.25621081086490266 0.3160401943112282 0.42868907378408033 +P12683 YML075C HMG1 0.309401621363989 0.30921361076561615 0.49465673260048365 0.5027216680795793 1.0 0.03416658657295133 0.03450825243870984 0.034508252438696436 0.03416658657305283 0.0596344142062684 0.11042794935051994 0.11160004358562046 0.06976201912239513 0.06796322645803357 0.0596344142062684 +P81450 YML081C-A ATP18 0.1860667845457803 0.27922934841457614 0.5299665414308693 0.8820433979562666 0.5896040184072173 0.007697081086696426 0.010473014036563663 0.013597631050320656 0.01750908629726654 0.020915297587768663 0.041367303172816526 0.03750685268589395 0.025657527385800787 0.01985059503629398 0.03547346513049586 Q04533 YML082W YML082W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P54783 YML086C ALO1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06457253658716347 0.09217665428276031 0.05476339656721177 0.04005495045658297 0.050706660719766275 -P38427 YML100W TSL1 0.0 0.0 0.0 0.0 0.3343002542050669 0.0 0.0 0.0 0.0 0.03494722296268555 0.3249010927951842 0.24170375519269885 0.17976395414628643 0.14596647347873642 0.10453842772505993 -P13298 YML106W URA5 0.00034256356755209467 0.00026649185924171396 0.0005082863789497285 0.0005352569709183385 0.0014252944070260948 2.079533926545174e-05 2.0795339265390205e-05 2.0795339265390233e-05 2.0795339265390226e-05 6.030648386963168e-05 0.06070505224490731 0.07803367549223475 0.040912643199999994 0.038851132064121906 0.0423115979213462 -P49017 YML110C COQ5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.009010800820485186 0.006237182217177395 0.0041154390707119955 0.004044760788232867 0.005012993303837189 -P32340 YML120C NDI1 0.2386651077654128 0.40421762237631986 0.6241476063785606 1.0 0.43937549650089813 0.08753957313287054 0.12016608008616388 0.14878792868547974 0.16774586447674722 0.2327636718412059 0.36678831670239115 0.29728065634479256 0.23838580355819913 0.16774586447674722 0.529760247658076 +P38427 YML100W TSL1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4102384712576349 0.3260643181195549 0.24847300439544773 0.19292047603471152 0.14863745465126157 +P13298 YML106W URA5 0.00034256356755108154 0.0002664918592417144 0.0005082863789497285 0.0005352569709183387 0.0014252944070260955 2.079533926539024e-05 2.0795339265390243e-05 2.079533926539023e-05 2.0795339265390233e-05 6.030648386963171e-05 0.06070505224490731 0.07803367549223475 0.040912643199999994 0.038851132064121906 0.0423115979213462 +P49017 YML110C COQ5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.009010800820485186 0.006237182217177395 0.0029486327658247635 0.0034589184287585335 0.005012993303837189 +P32340 YML120C NDI1 0.2386904663705064 0.39380673643941627 0.6301047146043836 1.0 0.40203801673728706 0.08754887437294674 0.11707112508171041 0.1502080187167757 0.16774586447674722 0.21298375931470687 0.36678831670239115 0.29728065634479256 0.23838580355819913 0.16774586447674722 0.529760247658076 P25297 YML123C PHO84 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q12746 YML125C PGA3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.013004868411890965 0.011889488577488267 0.005627737856411103 1000.0 -P54839 YML126C ERG13 0.06783383695417866 0.06843361310174008 0.07947695640921194 0.09001900317999587 0.36322675989845465 0.0735063430702022 0.07424140650076923 0.07424140649797681 0.07424140649972168 0.21317128513088274 1.0836235479330956 1.084867554638606 0.934124931957909 0.8247303777767192 0.5868821041447438 +P54839 YML126C ERG13 0.06783383695387406 0.06843361310161475 0.07947695641202485 0.08912772592207222 0.36322675989845465 0.07350634306987214 0.07424140650063325 0.07424140650060441 0.0735063430700905 0.21317128513088274 1.0836235479330956 1.084867554638606 0.934124931957909 0.8247303777767192 0.5868821041447438 Q03674 YMR006C PLB2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P39105 YMR008C PLB1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06076721131049813 0.06249981615486226 0.055269823356737004 0.0592346162305205 0.01978896721580308 -Q03677 YMR009W ADI1 3.861468717334737e-06 0.0005882924850174213 0.0006376591325268226 0.00067763105717835 0.0006333243948970644 2.2038945153692532e-07 2.8288116102032733e-05 1.5417247262455877e-05 1.426442868721884e-05 2.1264387159530646e-05 0.057073996365052136 0.04808512232005654 0.024177881999999998 0.021050435242174113 0.03357582201296193 +Q03677 YMR009W ADI1 3.861468728624313e-06 0.0005882924850174213 0.0006376591325268226 0.00067763105717835 0.0006333243948824359 2.203894521812665e-07 2.8288116102032733e-05 1.5417247262455877e-05 1.426442868721884e-05 2.1264387159039483e-05 0.057073996365052136 0.04808512232005654 0.024177881999999998 0.021050435242174113 0.03357582201296193 P23585 YMR011W HXT2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P20048 YMR013C SEC59 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P54781 YMR015C ERG5 0.0 1.0 1.0000000013521724 1.0 0.0 0.0 0.0500239614200397 0.03318487942782159 0.024413587236743646 0.0 0.01772962804858144 0.0500239614200397 0.033184879382949915 0.024413587236743646 0.026160979235632962 -P50264 YMR020W FMS1 7.82274953949773e-09 1.0040900127806641e-06 5.472370074050139e-07 5.063175762994422e-07 7.547819267205231e-07 7.82274953949773e-06 0.0010040900127806641 0.0005472370074050139 0.0005063175762994421 0.0007547819267205231 1000.0 1000.0 1000.0 1000.0 1000.0 +P54781 YMR015C ERG5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.033184879382949915 0.0 0.0 0.01772962804858144 0.0500239614200397 0.033184879382949915 0.024413587236743646 0.026160979235632962 +P50264 YMR020W FMS1 7.822749562368696e-09 1.0040900127806641e-06 5.472370074050139e-07 5.063175762994422e-07 7.547819267030891e-07 7.822749562368697e-06 0.0010040900127806641 0.0005472370074050139 0.0005063175762994421 0.0007547819267030891 1000.0 1000.0 1000.0 1000.0 1000.0 Q04212 YMR041C ARA2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P37296 YMR054W STV1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.013834525313617162 0.007475536745650731 0.0072338621994482415 0.008878537403771277 +P37296 YMR054W STV1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.27790852370023944 0.357821329376244 0.32975668521663526 0.2721384921894009 0.20865148229534308 P04710 YMR056C AAC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38993 YMR058W FET3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q04728 YMR062C ARG7 0.08641204858803331 0.08620968239504233 0.26817336697926847 0.3052706779348093 0.7918308076844819 0.012356298674200655 0.012356298674200655 0.019761391303747846 0.02021875310374564 0.057481877755252334 0.14299277561522603 0.14332843285026683 0.07368886599867142 0.06623221476929195 0.07259363641501171 -P07246 YMR083W ADH3 0.0 0.0 0.0 0.0015010108968009992 0.0 0.0 0.0 0.0 0.00047277792981910996 0.0 0.5893671444265082 0.5328491444265081 0.3605398017684509 0.31497301640295144 0.4436503946046802 +P07246 YMR083W ADH3 0.0 0.0 0.0 0.004005972247304267 0.0 0.0 0.0 0.0 0.0012617731623599353 0.0 0.5893671444265082 0.5328491444265081 0.3605398017684509 0.31497301640295144 0.4436503946046802 Q04299 YMR087W YMR087W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q04301 YMR088C VBA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q03161 YMR099C YMR099C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.140657271263572 0.1435388032 0.08731233988509848 0.07184385975018982 0.06730778894365028 Q03175 YMR101C SRT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P37012 YMR105C PGM2 0.020770295211557526 0.03438269909532802 0.08256545778229714 0.09587190118660052 0.34812163731125007 0.012061328936742347 0.012258563367983833 0.012168118618867935 0.012160017659397906 0.03512278945166759 0.5807008910509313 0.35653289853703046 0.14737541516395372 0.12683609596653586 0.10089229076061382 -P07342 YMR108W ILV2 0.006537190391737304 0.008830266109807798 0.013077542684554758 0.05301657337868857 0.021721304653662624 0.006561142598005447 0.0069787590457520195 0.006561142598005415 0.0229204035072472 0.019027313534124513 1.0036639909246665 0.7903226198359634 0.5017106620309072 0.43232525315302006 0.8759747095078908 -Q04458 YMR110C HFD1 0.0 0.0 9.595392622661675e-12 0.0 0.0 0.0 0.0 3.9897502164098e-13 0.0 0.0 0.07830710819117487 0.07627617170212146 0.04157985372049403 0.034546688600017694 0.021905190809891267 -Q12676 YMR113W FOL3 9.199454193987243e-09 9.199454193987252e-09 0.001401519107706227 0.0016649747952390212 2.6678417162571083e-08 9.199454193987243e-06 9.199454193987252e-06 9.199454193987252e-06 9.199454194228895e-06 2.6678417162571083e-05 1000.0 1000.0 0.006563916355762988 0.005525281355930818 1000.0 -P38009 YMR120C ADE17 0.06029055530797875 0.0632070966059038 0.0829931778695495 0.1004195342166577 0.14319391479600527 0.07840419894303043 0.07840419894302761 0.07840419894300239 0.07840419894318719 0.22737217693469697 1.3004391573858094 1.2404334822065586 0.9447065524619365 0.7807664072014927 1.5878620069757325 -P40215 YMR145C NDE1 0.0 0.3167113791873487 0.6647205051691516 0.0 0.0 0.0 0.056447257222357904 0.11781044013155077 0.0 0.0 0.280909860980515 0.178229330967508 0.1772330463937945 0.15528336426957304 0.30514887928407924 +P37012 YMR105C PGM2 0.020770295211565322 0.03438269909532802 0.08256545778229714 0.09587190118660052 0.3481216373112157 0.012061328936746874 0.012258563367983833 0.012168118618867935 0.012160017659397906 0.035122789451664124 0.5807008910509313 0.35653289853703046 0.14737541516395372 0.12683609596653586 0.10089229076061382 +P07342 YMR108W ILV2 0.006537190391741788 0.008301853487841767 0.013077542684554843 0.04986811960589564 0.021721304653766753 0.006561142598009947 0.006561142598005436 0.0065611425980054575 0.021559247432883916 0.019027313534215728 1.0036639909246665 0.7903226198359634 0.5017106620309072 0.43232525315302006 0.8759747095078908 +Q04458 YMR110C HFD1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.07830710819117487 0.07627617170212146 0.04157985372049403 0.034546688600017694 0.021905190809891267 +Q12676 YMR113W FOL3 9.199454193987252e-09 9.199454193983318e-09 0.001401519107706227 0.001664974795151553 2.6678417162571083e-08 9.199454193987252e-06 9.199454193983318e-06 9.199454193987252e-06 9.199454193745608e-06 2.6678417162571083e-05 1000.0 1000.0 0.006563916355762988 0.005525281355930818 1000.0 +P38009 YMR120C ADE17 0.06029055530815208 0.06320709660589596 0.08299317786955585 0.10041953421642921 0.1431939147960142 0.07840419894325583 0.07840419894301788 0.07840419894300839 0.0784041989430088 0.22737217693471115 1.3004391573858094 1.2404334822065586 0.9447065524619365 0.7807664072014927 1.5878620069757325 +P40215 YMR145C NDE1 0.0 0.3651834810393559 0.654242885193632 0.0 0.0 0.0 0.06508640750603005 0.11595345962433297 0.0 0.0 0.280909860980515 0.178229330967508 0.1772330463937945 0.15528336426957304 0.30514887928407924 Q12674 YMR162C DNF3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P32567 YMR165C PAH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P54114 YMR169C ALD3 4.646157495987484e-05 0.004248177806851554 8.520166192018282e-08 7.883074129923362e-08 1.175152149319297e-07 1.217957215121714e-06 0.00015754901057537878 8.520166192018282e-05 7.883074129923362e-05 0.00011751521493192969 0.026214290328590163 0.03708625621114076 1000.0 1000.0 1000.0 +P54114 YMR169C ALD3 4.6461575095712135e-05 0.004215336605348059 8.520166192018282e-08 7.942533176026275e-08 1.2002990630312464e-07 1.2179572186825921e-06 0.00015633105336213847 8.520166192018282e-05 7.942533176026275e-05 0.00012002990630312464 0.026214290328590163 0.03708625621114076 1000.0 1000.0 1000.0 P47771 YMR170C ALD2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.006428929420845675 0.005951994930110642 0.004140682006830598 0.0033679328590357333 0.001195730294552481 -P49095 YMR189W GCV2 0.24397968749775537 0.1616501868284959 0.999999999999844 1.000000000000297 0.7788465200151643 0.026434351047921845 0.03961068103190667 0.12547861856707965 0.10167164798187708 0.07443864365401784 0.1083465239218533 0.24503950047352524 0.12547861856709921 0.10167164798184687 0.09557549753521208 -P32352 YMR202W ERG2 0.0 0.025481573933137942 0.02177576880417019 0.01892942743733967 0.0 0.0 0.005581109843713914 0.0037023948519774672 0.002723792922021052 0.0 0.2054236382530838 0.21902531838725492 0.17002361134861224 0.14389198675117731 0.14954949349329866 -P16862 YMR205C PFK2 0.04306630923510056 0.0670603888554284 0.13517821886871667 0.2501475135286352 0.29475469159876205 0.0553540478155028 0.08745419976544072 0.1266538714503433 0.21326090095943503 0.3337450231828269 1.2853213753080865 1.3041111341298388 0.9369399338908874 0.8525405587732232 1.132280614 +P49095 YMR189W GCV2 0.08119253502199796 0.9001382728239322 0.131245979640785 1.0 0.3137471920583541 0.02643779830784463 0.7130281336688342 0.0502296941814211 0.33727979136575376 0.06707777306201135 0.3256185842784892 0.7921317815227518 0.38271415489371763 0.33727979136575376 0.21379561239080505 +P32352 YMR202W ERG2 0.0 0.0 0.0217757687747256 0.0 0.0 0.0 0.0 0.0037023948469711914 0.0 0.0 0.2054236382530838 0.21902531838725492 0.17002361134861224 0.14389198675117731 0.14954949349329866 +P16862 YMR205C PFK2 0.04959328030576241 0.07947708946532972 0.15964672682643463 0.30411663533332206 0.342004569738591 0.05535608775590545 0.08745419976544072 0.12688153155364135 0.21420783245204497 0.3358863119054945 1.1162013767714702 1.1003699349557945 0.7947643780481947 0.7043607865030664 0.9821105962479596 P32874 YMR207C HFA1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P07277 YMR208W ERG12 0.1753157323872569 0.17713187010574474 0.24922194905835046 0.29321830460220943 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YMR220W ERG8 0.990099009905436 1.000000000002672 0.9999999999650586 0.9999999999885613 0.9900990099009902 0.09120837520605686 0.09212045895794993 0.09212045895448502 0.0921204589566501 0.264507874358623 0.09212045895770378 0.09212045895770378 0.09212045895770384 0.09212045895770384 0.2671529531022092 +P38625 YMR217W GUA1 0.00014792537906854587 0.00019114176278785396 0.00027318124122710345 0.00027599250806231793 0.0004126100252870032 4.7056806217261684e-05 4.7056806217261684e-05 4.7056806217261684e-05 4.7056806217260186e-05 0.00013646473803005863 0.3181117838843356 0.2461879891182624 0.17225489570911645 0.17050030288008747 0.3307353909666555 +P24521 YMR220W ERG8 0.9900990099009899 1.0000000000008404 1.0000000000004514 0.9900990099039308 0.9900990099009903 0.09120837520564731 0.0921204589577812 0.09212045895774541 0.09120837520591826 0.264507874358623 0.09212045895770381 0.09212045895770378 0.09212045895770384 0.09212045895770384 0.26715295310220916 Q05016 YMR226C YMR226C 0.0 0.0 0.0 0.0 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5.906209000981077e-05 5.4740592304694584e-05 0.00044899006753461367 2.8814070205087175e-06 2.1152702343921726e-06 3.1942692125270347e-06 5.693216735375279e-06 1.1925870745876764e-05 0.03749630279940578 0.05279619631847483 0.05408324040000001 0.10400356473466629 0.026561546920984776 +P28834 YNL037C IDH1 0.0 0.0 0.04755189938499712 0.7143366710440907 0.0 0.0 0.0 0.032460672656549984 0.3373258762862628 0.0 0.6009687935091802 0.8719184352368066 0.6826367206436238 0.4722225386990418 1.0081637216672819 P53961 YNL038W GPI15 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q10740 YNL045W LAP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.056600230605659343 0.05675425706581272 0.03421714555023499 0.028760654894898367 0.03231396305510989 P53954 YNL048W ALG11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P00424 YNL052W COX5A 0.33068913983845544 0.0 0.11401216875957708 0.7154161024568377 0.6412724733187573 0.037014496265808106 0.0 0.008315569285263823 0.03885983214064273 0.05366894087675669 0.11193139358580088 0.09707207718974094 0.0729358047981638 0.054317804711401796 0.08369132172320685 -P53950 YNL054W VAC7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P53943 YNL065W AQR1 8.031475014664077e-05 0.002102607308142924 0.006797014683249274 0.013011869121048833 0.0002329127754252582 0.08031475014664077 2.1026073081429244 6.797014683249274 13.011869121048832 0.2329127754252582 1000.0 1000.0 1000.0 1000.0 1000.0 -P12695 YNL071W LAT1 1.0 0.33921312290225264 0.7419046578784385 0.9485842287951375 1.0 1.1578756792637974 0.15091837429017363 0.2076430194920216 0.24008974066063235 0.5684008929167875 1.1578756792637974 0.44490724002344134 0.27987830685118037 0.2531032388822097 0.5684008929167875 +P00424 YNL052W COX5A 0.20151667323204328 0.32950143624461603 0.5389014434584413 0.8953092692728255 0.8482724115955427 0.015714861889583365 0.022255995405052777 0.028649680697167036 0.03566064581736937 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2.2010651245613963e-05 4.548380576400166e-07 0.0 0.09476107124888865 0.0 0.022010651245613962 0.0004548380576400166 1000.0 1000.0 1000.0 1000.0 1000.0 P53915 YNL129W NRK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0011497189636754696 1000.0 0.005011172771243506 0.005926333769667911 1000.0 P17898 YNL130C CPT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P53909 YNL141W AAH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.00448987121159759 0.005870215704390169 0.007955481778130996 0.008866534455722297 0.007265663033396541 P41948 YNL142W MEP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.01240173939423033 1000.0 1000.0 1000.0 1000.0 -P39006 YNL169C PSD1 1.0 1.891026406861204e-07 0.8943107596699161 0.8864873626329558 1.0 0.00013283951171441457 0.0001891026406861204 0.00019207813978222265 0.0001920781397822225 0.0004314848361789536 0.00013283951171441457 1000.0 0.00021477784730345562 0.00021667329719369185 0.0004314848361789536 -P53871 YNL191W DUG3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P39006 YNL169C PSD1 1.0 1.8910264068612344e-07 0.8943107596699144 0.8864873626329505 1.0 0.00013283951171441457 0.00018910264068612342 0.00019207813978222227 0.00019207813978222135 0.0004314848361789536 0.00013283951171441457 1000.0 0.00021477784730345562 0.00021667329719369185 0.0004314848361789536 +P53871 YNL191W DUG3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.01150010939865655 0.014225495896711755 0.007291364833435688 0.005777665398112546 0.008260980254539767 P08004 YNL192W CHS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P32573 YNL202W SPS19 0.0 0.0020552473008419968 0.0 0.0 0.0 0.0 0.0001104168757728475 0.0 0.0 0.0 0.1283727178738387 0.05372437454490842 0.008783406075530756 0.006094875279999999 0.009858011968763873 +P32573 YNL202W SPS19 0.0 0.0 0.0 0.11649568717636918 0.0 0.0 0.0 0.0 0.0007100266839978655 0.0 0.1283727178738387 0.05372437454490842 0.008783406075530756 0.006094875279999999 0.009858011968763873 P53868 YNL219C ALG9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.01834568331359194 0.0251091179298224 0.017009147856795866 0.01446442173879292 0.015029933791384122 -P80210 YNL220W ADE12 0.06940174075495717 0.08518016527419445 0.11716966020944608 0.11927110542197664 0.18611158817242046 0.0336421530317818 0.03364215303178025 0.03364215303176559 0.03364215303187207 0.0975622437921145 0.4847450894721086 0.3949528968802345 0.28712341549534853 0.2820645697283295 0.524213697546492 +P80210 YNL220W ADE12 0.06940174075522612 0.08518016527418001 0.11716966020945815 0.1192711054216136 0.18611158817243612 0.03364215303191217 0.03364215303177455 0.03364215303176906 0.033642153031769664 0.09756224379212271 0.4847450894721086 0.3949528968802345 0.28712341549534853 0.2820645697283295 0.524213697546492 P23202 YNL229C URE2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 0.021370173391063552 -P11412 YNL241C ZWF1 0.01139581585852225 0.0007174196540795719 0.0 0.0 0.007817612061282533 0.00792247953936734 0.000489414734490143 0.0 0.0 0.004323417168247867 0.6952095082725114 0.6821875198248473 0.430149516 0.3840190708851848 0.5530355221462065 +P11412 YNL241C ZWF1 0.011392594849250998 0.0011797457971410522 0.0 0.0 0.0034150256906535573 0.007920240263095733 0.0008048078593754418 0.0 0.0 0.0018886305159732998 0.6952095082725114 0.6821875198248473 0.430149516 0.3840190708851848 0.5530355221462065 P53852 YNL247W YNL247W 0.007260895020135733 0.009697453559984255 0.012813978021152377 0.014765322299889262 0.017560856500532983 0.0006431109164638971 0.0006431109164638971 0.0006431109164638971 0.0006431109164638971 0.0018650216577453013 0.08857185163543033 0.06631750412475719 0.05018823314682581 0.043555494651730045 0.10620334251286073 -P53848 YNL256W FOL1 1.6685329599623535e-06 0.08782033744356013 0.18667823139182402 2.0709804074340937e-06 0.40127854827301734 0.0016685329599623534 0.0016685329599623552 0.002070980407379695 0.002070980407434094 0.004838745583892291 1000.0 0.01899939135436229 0.011093850589535841 1000.0 0.012058321095699738 +P53848 YNL256W FOL1 1.6685329599623552e-06 0.08782033744352256 0.18667823139182402 2.070980407325297e-06 0.40127854827301734 0.0016685329599623552 0.0016685329599616416 0.002070980407379695 0.002070980407325297 0.004838745583892291 1000.0 0.01899939135436229 0.011093850589535841 1000.0 0.012058321095699738 P39104 YNL267W PIK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P32487 YNL268W LYP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38971 YNL270C ALP1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P53839 YNL274C GOR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1707048613764505 0.22499988147523012 0.07401054492814044 0.06748079073595094 0.03180895042231668 P53838 YNL275W BOR1 2.1183364355767248e-07 2.1183364355767248e-07 2.1183364355767248e-07 2.1183364355767248e-07 6.143175663172502e-07 0.0002118336435576725 0.0002118336435576725 0.0002118336435576725 0.0002118336435576725 0.0006143175663172502 1000.0 1000.0 1000.0 1000.0 1000.0 -P08465 YNL277W MET2 0.15112149885831758 0.17520322121107162 0.24193487660653823 0.3111626175889146 0.5067263120626663 0.011693579340050192 0.011693579340050334 0.01169357934004979 0.011693579340089383 0.033911380086145526 0.07737866172842416 0.06674294718567299 0.04833358259076969 0.03758028336018849 0.0669224772404393 -P32462 YNL280C ERG24 1.546803851778942e-05 1.5622718902938905e-05 0.9999999999650593 1.562271890271847e-05 4.485731170138788e-05 0.015468038517789419 0.015622718902938907 0.015622718902351293 0.015622718902718468 0.04485731170138788 1000.0 1000.0 0.015622718902897162 1000.0 1000.0 +P08465 YNL277W MET2 0.15112149885902154 0.17520322121106746 0.24193487660654922 0.3111626175877453 0.5067263120626542 0.011693579340104666 0.011693579340050057 0.01169357934005032 0.01169357934004544 0.033911380086144714 0.07737866172842416 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0.00021574476169689292 0.00021574476169689292 0.00021574476169689295 0.00021574476169689292 0.0006256598089209894 0.015836415904029226 0.011456055111837263 0.009073628145164695 0.0061492076115524695 0.007809856255370541 P42833 YNL318C HXT14 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P42837 YNL325C FIG4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P42837 YNL325C FIG4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.001374875094822551 0.0019268296941745509 0.0019276527928035235 0.0015012821522878725 0.0008568926624587876 P42884 YNL331C AAD14 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P53824 YNL333W SNZ2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P53823 YNL334C SNO2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P0CH64 YNL335W DDI3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P00890 YNR001C CIT1 0.05597169070292898 0.11535438756986494 0.2718816284250485 0.412787431910406 0.13533585414843918 0.0927723186887165 0.1331783587721255 0.16211773021888165 0.17256533955354672 0.26245166779054524 1.6574864458018195 1.1545148960325882 0.5962805620887098 0.4180489186768685 1.939261915786801 -P40345 YNR008W LRO1 0.0 0.0009408958371689341 0.0 0.0 0.0 0.0 0.9408958371689341 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P00890 YNR001C CIT1 0.055977860030119474 0.11455712475318523 0.2724828116529181 0.4215029033247005 0.12413295663304265 0.09278254426491446 0.13225790697421588 0.16247620409191407 0.17620883295405168 0.24072631529247418 1.6574864458018195 1.1545148960325882 0.5962805620887098 0.4180489186768685 1.939261915786801 +P40345 YNR008W LRO1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P27515 YNR012W URK1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P27514 YNR013C PHO91 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 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YOL052C SPE2 0.0036000152182425705 0.41891909860085624 0.3756860858299296 0.44193401843791785 0.5425094109501096 0.0001435307239929272 0.018422904292086012 0.01004062871274909 0.00928984466615064 0.013848634106556732 0.03986947701376523 0.04397723654427905 0.026726112814554465 0.021020886101927594 0.0255269933148317 +Q08224 YOL055C THI20 9.499070103432113e-09 7.073093994939201e-09 7.073093994939201e-09 7.073093994939201e-09 2.754730329995312e-08 9.499070103432113e-06 7.0730939949392e-06 7.0730939949392e-06 7.0730939949392e-06 2.754730329995312e-05 1000.0 1000.0 1000.0 1000.0 1000.0 P22768 YOL058W ARG1 0.314991263051716 0.2067452298089327 0.20372629518521054 0.25001142807781573 0.9900990099009901 0.3181606933703285 0.3181606933703285 0.3181606933703285 0.3181606933703285 0.9226660107739524 1.0100619626332052 1.5389022211751264 1.561706568516764 1.2725846006979384 0.9318926708816919 P41911 YOL059W GPD2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.15025089710473755 0.18568833840000004 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0.9900990099009901 0.9900990099009901 0.9900990099009901 0.9900990099009901 0.018809202598948565 0.018809202598948565 0.018809202598948565 0.018809202598948565 0.05454668753695083 0.01899729462493805 0.01899729462493805 0.01899729462493805 0.01899729462493805 0.055092154412320335 +Q12362 YOL066C RIB2 0.9900990099009901 0.9900990099009764 0.9900990099009901 0.9900990099009901 0.9900990099009902 0.018809202598948565 0.018809202598948305 0.018809202598948565 0.018809202598948565 0.05454668753695083 0.01899729462493805 0.01899729462493805 0.01899729462493805 0.01899729462493805 0.05509215441232033 P53685 YOL068C HST1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P81451 YOL077W-A ATP19 1.0000000000000002 1.0 1.0 1.0 1.0000000000003733 0.16466294862201772 0.20978050089223513 0.28862025255026563 0.3560177667375588 0.482916190474053 0.1646629486220177 0.20978050089223513 0.28862025255026563 0.3560177667375588 0.48291619047387274 -P00330 YOL086C ADH1 0.0 0.0004502093752000395 0.002363112531542493 0.007909698434586013 0.014395608258804368 0.0 0.0022893996714191383 0.008494608019371496 0.022823131044747546 0.038622400641181526 2.555487265784503 5.085188797771925 3.5946692787527748 2.8854615929415126 2.682929400885859 +P81451 YOL077W-A ATP19 0.1860667845457803 0.27922934841457603 0.5299665414308693 0.8820433979562665 0.5896040184072172 0.008670725016024353 0.011797800202073957 0.015317666317750571 0.019723901938338236 0.023560982659427198 0.04660006909449756 0.04225129009203425 0.02890308183681566 0.02236160032946155 0.03996068874000536 +P00330 YOL086C ADH1 0.0 0.00030832847127520996 0.002362569618950466 0.006902584666767823 0.01604449336744395 0.0 0.0015679084881628402 0.00849265642815589 0.019917142947985543 0.043046242977833535 2.555487265784503 5.085188797771925 3.5946692787527748 2.8854615929415126 2.682929400885859 Q12010 YOL092W YPQ1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P27680 YOL096C COQ3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P27680 YOL096C COQ3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.009438414433012752 0.006533171893679457 0.0030885621166261926 0.0036230637288518458 0.005250888272213029 Q12109 YOL097C WRS1 0.031049381117295417 0.03533625448618042 0.04855211816503645 0.05720013537470737 0.09002505871695853 0.0021580729518423042 0.0021580729518423042 0.0021580729518423042 0.0021580729518423042 0.006258411560342682 0.06950454 0.06107248725770583 0.0444485850134626 0.03772845881753903 0.06951855016300867 P30606 YOL103W ITR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P38925 YOL122C SMF1 1.3994763724534114e-07 1.3994763724534114e-07 1.3994763724534114e-07 1.3994763724534114e-07 4.0584814801148926e-07 0.00013994763724534115 0.00013994763724534115 0.00013994763724534115 0.00013994763724534115 0.0004058481480114893 1000.0 1000.0 1000.0 1000.0 1000.0 -P22133 YOL126C MDH2 2.9160580226215343e-05 6.204232590276964e-05 0.00021217752974952785 0.0007580797645637448 0.0009558948826497214 1.0315557406576698e-05 8.936248969128004e-06 8.861666667469093e-06 2.319794495935121e-05 4.286435162949927e-05 0.353750073782929 0.144034718864869 0.04176533998642622 0.030600928878112218 0.04484211852947695 +P22133 YOL126C MDH2 2.916058022292262e-05 4.247264042011393e-06 0.0002353225372835865 0.000985554909544089 0.0009558948826517207 1.0315557405411897e-05 6.117534822359781e-07 9.82832577611745e-06 3.0158895692432988e-05 4.286435162958892e-05 0.353750073782929 0.144034718864869 0.04176533998642622 0.030600928878112218 0.04484211852947695 Q08269 YOL130W ALR1 6.609150916484968e-07 6.609150916484968e-07 6.609150916484968e-07 6.609150916484968e-07 1.9166537657806405e-06 0.0006609150916484968 0.0006609150916484968 0.0006609150916484968 0.0006609150916484968 0.0019166537657806404 1000.0 1000.0 1000.0 1000.0 1000.0 Q12471 YOL136C PFK27 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P18544 YOL140W ARG8 0.5003760749078202 0.6574791773287527 1.0 1.0 0.9999999999999998 0.11340012933896819 0.11340012933896819 0.18136048576115663 0.18555793101899462 0.5275408553940656 0.2266297991163124 0.17247714186127885 0.18136048576115663 0.18555793101899462 0.5275408553940657 -P50861 YOL143C RIB4 0.0022765924119901313 0.0023034086424903767 0.004580167980324618 0.005722523064411701 0.015050779902389585 0.0002811488318741518 0.0002811488318741518 0.0002811488318741518 0.0002811488318741518 0.00081533161243504 0.12349546207455712 0.12205773074211534 0.06138395645790823 0.049130222580073615 0.054172050732440205 -Q12068 YOL151W GRE2 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.06926843031545774 0.054513586810007474 0.0 0.08028550404320083 0.12995024565549085 0.06926843031545774 0.054513586810007474 0.010722460119414277 +P50861 YOL143C RIB4 0.0022765924119901313 0.0023034086424903446 0.004580167980324618 0.005722523064411701 0.015050779902389585 0.0002811488318741518 0.0002811488318741479 0.0002811488318741518 0.0002811488318741518 0.00081533161243504 0.12349546207455712 0.12205773074211534 0.06138395645790823 0.049130222580073615 0.054172050732440205 +Q12068 YOL151W GRE2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.06926843031545774 0.0 0.0 0.08028550404320083 0.12995024565549085 0.06926843031545774 0.054513586810007474 0.010722460119414277 Q12333 YOL152W FRE7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P54862 YOL156W HXT11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q08295 YOL157C IMA2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 @@ -986,163 +986,163 @@ Q12001 YOR002W ALG6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 Q08409 YOR011W AUS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P53687 YOR025W HST3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q12320 YOR040W GLO4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q08438 YOR054C VHS3 1.3403554071194294e-07 0.038890576763579834 0.06382508762820498 1.3403554099388527e-07 0.24766023062550063 0.00013403554071194295 0.00013403554071289748 0.00013403554070902886 0.00013403554099388526 0.0003887030680642699 1000.0 0.0034464786040000004 0.002100044758102254 1000.0 0.0015695013570913093 -P07143 YOR065W CYT1 0.5821562574079976 0.9338617272706927 0.9999999999999838 1.0000000000000395 1.0000000000003961 0.17422161679116194 0.2418084996646338 0.3154607136651548 0.3884296832863061 0.5213491386543342 0.29926950809885516 0.25893394343437126 0.31546071366515993 0.38842968328629074 0.5213491386541277 +Q08438 YOR054C VHS3 0.005007347964173927 0.01398117015595235 0.017103776915961155 0.011962653245345097 0.0476655898826369 0.0001340355411038157 0.00013403554071093947 0.00013403554071279806 0.00013403554067773423 0.00038870306805849375 0.026767770497037515 0.009586861415449916 0.007836604825435767 0.01120449936387566 0.008154794035184829 +P07143 YOR065W CYT1 0.2048450648356407 0.3048373008509114 0.4208383985454061 0.892359746616224 0.6186205673623894 0.034854939675796406 0.04936291408212197 0.06307304331404819 0.07881050659867457 0.09656529052930887 0.17015269420214046 0.16193200092092466 0.14987473465362253 0.08831696734138827 0.15609776917219872 P40351 YOR067C ALG8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q08485 YOR071C NRT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P06785 YOR074C CDC21 0.0019565971689782763 0.0018845692683061882 0.0030314831293000687 0.0028084542555129807 0.007090105206469729 7.30145820791087e-05 7.30145820791087e-05 7.30145820791087e-05 7.30145820791087e-05 0.00021174228802941519 0.037317125485383636 0.03874337935306177 0.024085432431869364 0.02599813827687649 0.0298644775871873 -Q12043 YOR081C TGL5 5.059285839476269e-07 3.1887113447258892e-15 7.968256017488778e-07 7.968256017489432e-07 2.30245060445112e-06 0.0005059285839476269 3.188711344725889e-12 0.0007968256017488778 0.0007968256017489432 0.00230245060445112 1000.0 1000.0 1000.0 1000.0 1000.0 -Q12189 YOR095C RKI1 1.0000000000018372 1.0 1.0 1.0 1.0 0.07580034815653519 0.026336479661299296 0.020970191086738973 0.026838128429107724 0.08586825962325949 0.07580034815639593 0.026336479661299296 0.020970191086738973 0.026838128429107724 0.08586825962325949 +Q12043 YOR081C TGL5 5.71361480257099e-14 1.991367362218303e-06 7.968256017489683e-07 7.968256017489786e-07 2.302450604451357e-06 5.7136148025709893e-11 0.001991367362218303 0.0007968256017489683 0.0007968256017489786 0.002302450604451357 1000.0 1000.0 1000.0 1000.0 1000.0 +Q12189 YOR095C RKI1 1.0000000000005471 1.0 1.0 1.0 1.0 0.07578418269692783 0.026336479661299296 0.019101433407158478 0.01906520083565863 0.06829139970481886 0.07578418269688636 0.026336479661299296 0.019101433407158478 0.01906520083565863 0.06829139970481886 P27810 YOR099W KTR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0219908697833278 0.03700296638847931 0.022810776622804115 0.025251396738091222 0.02859314792814857 -Q12289 YOR100C CRC1 0.0 0.0066876095814533375 0.1162077598713798 0.17103489515684497 0.0 0.0 0.00019037174054640184 0.00788394778260601 0.00860559303931185 0.0 0.029969381360334554 0.0284663358749825 0.06784355701660597 0.050314837983326276 0.04055782254367946 -Q12166 YOR108W LEU9 0.0 0.0 5.61132327311494e-06 0.0003224769314020637 1.0 0.0 0.0 0.00561132327311494 0.3224769314020637 0.03577359738419447 0.0577316859377644 0.04897146220802612 1000.0 1000.0 0.03577359738419447 +Q12289 YOR100C CRC1 0.0 0.0 0.1132676182455027 0.029438620439599293 0.0 0.0 0.0 0.0076844781165739205 0.0014811994178710757 0.0 0.029969381360334554 0.0284663358749825 0.06784355701660597 0.050314837983326276 0.04055782254367946 +Q12166 YOR108W LEU9 0.0 0.0 5.611323273266127e-06 0.00029972858918023485 1.0 0.0 0.0 0.005611323273266126 0.2997285891802349 0.03577359738419447 0.0577316859377644 0.04897146220802612 1000.0 1000.0 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YPL015C HST2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P46151 YPL023C MET12 0.1151731791080317 0.09629316121247929 0.12914064782274867 0.16873905798887093 0.3723707207793662 0.0028516930337032023 0.0028345176337610674 0.002856984408276243 0.0028569844082782674 0.00828549767672111 0.024760044446010585 0.02943633377562978 0.02212304534973049 0.01693137583159139 0.022250669062754694 -P41338 YPL028W ERG10 0.15476747389979056 0.1456305237549473 0.29948873322731695 0.22690317900386098 0.854346677113315 0.07327897041216393 0.07401176011615099 0.11362330917534638 0.07401176011510667 0.2125118954824091 0.4734778475457374 0.5082159852744242 0.37939093050657235 0.326182120673802 0.24874199335619687 +P46151 YPL023C MET12 0.115045422537881 0.09629316121248002 0.12914064782274856 0.16873905798875066 0.3723707207793649 0.0028485297753480013 0.002834517633761089 0.00285698440827624 0.0028569844082762313 0.008285497676721081 0.024760044446010585 0.02943633377562978 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1000.0 1000.0 -P54115 YPL061W ALD6 0.015440214834916765 0.042969603689517064 0.08557701866385566 0.11082304031335148 0.3021151250521573 0.09420595932491074 0.21482056082554926 0.19049618360466358 0.2178316927133089 0.8447169001673053 6.101337340972211 4.999360998946268 2.2260203332500716 1.9655812735094715 2.7960099648154753 +P54115 YPL061W ALD6 0.015440214834888909 0.050929171455448626 0.10083220478039356 0.36531422871341684 0.4002621514926257 0.09420595932474078 0.2546133134830174 0.22445453808759114 0.7180548069056483 1.1191369641118627 6.101337340972211 4.999360998946268 2.2260203332500716 1.9655812735094715 2.7960099648154753 Q12051 YPL069C BTS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P46961 YPL076W GPI2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P05626 YPL078C ATP4 1.0 0.9999999999999999 1.0 1.0 1.0000000000003733 0.5884722447103565 0.7497132979192236 1.0314707061210382 1.272335860022401 1.7258452918123013 0.5884722447103565 0.7497132979192237 1.0314707061210382 1.272335860022401 1.7258452918116571 +P05626 YPL078C ATP4 0.1860667845457803 0.2792293484145761 0.5299665414308694 0.8820433979562665 0.5896040184072173 0.03098742647417782 0.042162963955513846 0.05474225718150175 0.07048925666176759 0.08420221105721759 0.1665392700251323 0.15099760893655723 0.10329379857396623 0.07991585995098915 0.1428114606218004 Q02896 YPL087W YDC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q02895 YPL088W YPL088W 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P41921 YPL091W GLR1 0.0 1.5360793846039358e-07 8.289566692794027e-08 7.344592948200255e-08 0.0 0.0 0.0001536079384603936 8.289566692794027e-05 7.344592948200255e-05 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P41921 YPL091W GLR1 0.0 0.0 8.289566692794027e-08 0.0 0.0 0.0 0.0 8.289566692794027e-05 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P41930 YPL092W SSU1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q02891 YPL095C EEB1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q02891 YPL095C EEB1 0.0 1.152294810544982e-13 0.0 2.2411103815269283e-14 0.0 0.0 1.1522948105449818e-10 0.0 2.2411103815269283e-11 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P62651 YPL096C-A ERI1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P48527 YPL097W MSY1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.00576145132838256 0.0038540799230970795 0.0021205948321731585 0.018230968663875968 P15179 YPL104W MSD1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q02979 YPL110C GDE1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P00812 YPL111W CAR1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.018113815747917237 0.010914452219627535 0.003139901818914701 0.0024325396298090487 0.005735118953652761 -P15496 YPL117C IDI1 0.10332504546151089 0.10572581065300082 0.16240326122351914 0.16453908419418475 0.48284854340825695 0.008262368178368614 0.008344991860137124 0.008344991859823247 0.008344991860019378 0.02396119258885208 0.07996481532104807 0.07893050721101534 0.05138438598432979 0.05071738365925773 0.049624655424490884 +P15496 YPL117C IDI1 0.10332504546104693 0.1057258106528072 0.16240326122926704 0.1629099843530253 0.48284854340825695 0.008262368178331514 0.008344991860121841 0.008344991860118599 0.008262368178356058 0.02396119258885208 0.07996481532104807 0.07893050721101534 0.05138438598432979 0.05071738365925773 0.049624655424490884 Q02948 YPL120W VPS30 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P19516 YPL132W COX11 0.0 0.6617329222160458 1.0 1.0 1.0000000000025877 0.0 0.10320076636278096 0.11695754905261234 0.08700757193859732 0.11340389402506607 0.18088591683034522 0.15595531504942634 0.11695754905261234 0.08700757193859732 0.1134038940247726 +P19516 YPL132W COX11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.015143151658142413 0.008546284500914563 0.0053183080288286685 0.0034870210477211065 0.007751080353798107 Q03028 YPL134C ODC1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.028850933059178012 0.0 0.0 0.052398691159186994 0.054199837738845145 0.028850933059178012 0.021232152586720933 0.039648269935097034 -P41909 YPL147W PXA1 0.0 1.0 0.00036855681448499814 0.0001593683625484638 0.0 0.0 0.0006545909892502709 0.36855681448499816 0.15936836254846382 0.0 1000.0 0.0006545909892502709 1000.0 1000.0 1000.0 -Q12036 YPL148C PPT2 0.0 0.0 2.2052303026939707e-05 2.5179398716078993e-05 0.0 0.0 0.0 0.022052303026939706 0.025179398716078993 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P41909 YPL147W PXA1 0.0 0.0 0.00036709137913323116 1.689069109092541e-05 0.0 0.0 0.0 0.36709137913323114 0.01689069109092541 0.0 1000.0 0.0006545909892502709 1000.0 1000.0 1000.0 +Q12036 YPL148C PPT2 0.0 0.0 2.2052303026939707e-05 2.517939871616779e-05 8.771541646222189e-07 0.0 0.0 0.022052303026939706 0.02517939871616779 0.0008771541646222188 1000.0 1000.0 1000.0 1000.0 1000.0 P26637 YPL160W CDC60 0.06720718390502708 0.07279796136748723 0.11298206550515633 0.13139692837477396 0.149906369432583 0.03333656796809685 0.03333656796809685 0.03333656796809685 0.03333656796809685 0.09667604710748084 0.49602685354598347 0.4579327132502025 0.29506070560000003 0.25370888330824115 0.6449095356882665 P21592 YPL172C COX10 0.0 0.0 0.0 0.0 4.77855194666033e-10 0.0 0.0 0.0 0.0 4.77855194666033e-07 1000.0 1000.0 1000.0 1000.0 1000.0 P32363 YPL175W SPT14 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q06892 YPL188W POS5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03694481487604194 0.03552983968403946 0.020000786678627994 0.016101184154002024 0.01667199158192779 Q08929 YPL189W GUP2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q08959 YPL206C PGC1 0.0 0.7785250485795235 0.015840644321052793 0.015447012485081756 0.0 0.0 0.03186829763184925 0.0005046954518793926 0.00043164786421142894 0.0 0.009960037629414742 0.04093419690220027 0.03186079061245217 0.027943776482883084 1000.0 +Q08959 YPL206C PGC1 0.0 0.0 0.015840644321052793 0.015447012485081759 0.0 0.0 0.0 0.0005046954518793926 0.00043164786421142905 0.0 0.009960037629414742 0.04093419690220027 0.03186079061245217 0.027943776482883084 1000.0 Q12211 YPL212C PUS1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.03795733863711944 0.036338300270966746 0.022690272974025667 0.018446528119999996 0.029967370026136492 -P41835 YPL214C THI6 0.0 0.0 1.214189334385453e-09 1.214189334385453e-09 3.521149069717813e-09 0.0 0.0 1.214189334385453e-06 1.214189334385453e-06 3.521149069717813e-06 1000.0 1000.0 1000.0 1000.0 1000.0 +P41835 YPL214C THI6 1.214189334385453e-09 0.0 0.0 1.214189334385453e-09 3.521149069717813e-09 1.214189334385453e-06 0.0 0.0 1.214189334385453e-06 3.521149069717813e-06 1000.0 1000.0 1000.0 1000.0 1000.0 P40350 YPL227C ALG5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P19097 YPL231W FAS2 0.13201922215585793 0.12079080328582423 0.28044710933175215 0.30211581375544094 0.7571915876533546 0.42844850193403655 0.4107737460462363 0.6241273706226276 0.5211074732293611 1.346174342676647 3.2453493888050873 3.40070381909981 2.225472646552838 1.7248599692672535 1.777851688564891 -P32842 YPL234C VMA11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.027629895257528795 0.02288224667393769 0.021450260669856388 1000.0 +P19097 YPL231W FAS2 0.14085011244699638 0.12644534459377774 0.2973691028454214 0.25256033285746604 0.8045469318450529 0.42844850192184747 0.41029723037610916 0.6254157576965931 0.41453918056363004 1.346174342676647 3.041875469450391 3.2448583353878537 2.1031632126949553 1.6413471421799943 1.6732079750642885 +P32842 YPL234C VMA11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.046573686254128714 0.05996598487702333 0.055262732473965584 0.045606707502688575 0.03496714869877102 Q12520 YPL244C HUT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q12184 YPL252C YAH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0037154916901318753 0.0030950033600000005 0.0023644201628178533 0.0020222261566205904 0.004785279867831492 Q08975 YPL258C THI21 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P08417 YPL262W FUM1 0.021755136686990646 0.042652767266748055 0.07802195526143671 0.1266389662842045 0.048645437732652674 0.011283276843059787 0.016808884173160468 0.02097945026848038 0.022742591213082506 0.03182556278895853 0.518648860055523 0.3940866032920826 0.2688916241355685 0.17958604590978214 0.6542353049399328 +P08417 YPL262W FUM1 0.021757817829906413 0.04225696812080878 0.07765936525390867 0.12601001455624158 0.044128743298322615 0.011284667414776696 0.01665290503215135 0.020881952852460837 0.022629640259189517 0.02887058182839411 0.518648860055523 0.3940866032920826 0.2688916241355685 0.17958604590978214 0.6542353049399328 P53388 YPL265W DIP5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P32383 YPL268W PLC1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P21306 YPL271W ATP15 1.0 0.9999999999999999 1.0 1.0000000000000002 1.0000000000003733 0.1473748689352622 0.1877554974139025 0.2583178076647785 0.31863920906707716 0.43221447735154495 0.1473748689352622 0.18775549741390252 0.2583178076647785 0.3186392090670771 0.43221447735138363 +P21306 YPL271W ATP15 0.18606678454578024 0.2792293484145761 0.5299665414308693 0.8820433979562665 0.5896040184072172 0.0077603794508962305 0.01055914079673277 0.013709453674089739 0.017653075493790114 0.02108729839029965 0.041707494810750874 0.037815297198113475 0.02586852678864454 0.020013840061263503 0.03576518770558217 Q08985 YPL273W SAM4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q08986 YPL274W SAM3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q08992 YPL280W HSP32 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P0CX11 YPL281C ERR2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -P43635 YPR001W CIT3 0.0 0.0 0.0 7.921050065520132e-09 0.0 0.0 0.0 0.0 7.921050065520132e-06 0.0 0.06246187050936882 0.04279658620522321 1000.0 1000.0 1000.0 -Q12428 YPR002W PDH1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.026662244805253855 0.0 0.5362678599249557 0.2817033936083357 0.019654092480000003 0.026662244805253855 0.16431195181894923 +P43635 YPR001W CIT3 0.0 4.943643052766672e-05 0.0 7.921050065520132e-09 4.881521440628138e-08 0.0 2.115710460755817e-06 0.0 7.921050065520132e-06 4.881521440628138e-05 0.06246187050936882 0.04279658620522321 1000.0 1000.0 1000.0 +Q12428 YPR002W PDH1 0.0 0.0252800604378047 0.0 1.0 1.0 0.0 0.007121478815953412 0.0 0.026662244805253855 0.16431195181894923 0.5362678599249557 0.2817033936083357 0.019654092480000003 0.026662244805253855 0.16431195181894923 P53394 YPR003C YPR003C 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q12031 YPR006C ICL2 0.0 0.0 0.0 1.0238418986906962e-07 0.0 0.0 0.0 0.0 0.00010238418986906962 0.0 0.31490609899738575 0.21467254754297216 0.017060084804136743 1000.0 0.05293894605498735 -Q12251 YPR011C YPR011C 0.0 0.0 1.0 1.5837889134059322e-06 0.0 0.0 0.0 0.0013870940066107343 0.001583788913405932 0.0 1000.0 1000.0 0.0013870940066107343 1000.0 1000.0 -Q12233 YPR020W ATP20 1.0 1.0 1.0 1.0000000000000002 1.0000000000003733 0.28240110952284186 0.35977884948613886 0.49499101183992333 0.6105794483695245 0.8282134453298697 0.28240110952284186 0.35977884948613886 0.49499101183992333 0.6105794483695244 0.8282134453295606 -Q12482 YPR021C AGC1 1.0 1.0 0.00018387847225413573 0.0006269078360148603 0.0007094205735974433 0.005247130672104108 0.002572137794239356 0.18387847225413573 0.6269078360148603 0.7094205735974433 0.005247130672104108 0.002572137794239356 1000.0 1000.0 1000.0 +Q12031 YPR006C ICL2 0.0 0.0001273883942034202 0.0 1.0238418986906962e-07 0.01191873188377173 0.0 2.7346791111056606e-05 0.0 0.00010238418986906962 0.0006309651042388494 0.31490609899738575 0.21467254754297216 0.017060084804136743 1000.0 0.05293894605498735 +Q12251 YPR011C YPR011C 0.0 0.0 1.0 1.5837889134115175e-06 5.5173161874965e-08 0.0 0.0 0.0013870940066107343 0.0015837889134115175 5.5173161874965e-05 1000.0 1000.0 0.0013870940066107343 1000.0 1000.0 +Q12233 YPR020W ATP20 0.18606678454578027 0.2792293484145761 0.5299665414308693 0.8820433979562664 0.5896040184072172 0.014870512069558089 0.020233524875364693 0.026270184031278884 0.033826989241474426 0.0404076794455082 0.07992029370453982 0.0724620280434264 0.04956951425716686 0.03835070850238555 0.06853358895800493 +Q12482 YPR021C AGC1 1.0 1.0 0.00018387847225434582 0.0005952962153017427 0.0007094205735995631 0.005247130672104108 0.002572137794239356 0.1838784722543458 0.5952962153017427 0.7094205735995631 0.005247130672104108 0.002572137794239356 1000.0 1000.0 1000.0 P48016 YPR026W ATH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P07263 YPR033C HTS1 3.4792344478061566e-06 3.4792344478061566e-06 3.4792344478061566e-06 3.4792344478061566e-06 1.0089779898637854e-05 0.0034792344478061566 0.0034792344478061566 0.0034792344478061566 0.0034792344478061566 0.010089779898637853 1000.0 1000.0 1000.0 1000.0 1000.0 -P32288 YPR035W GLN1 0.01581203809346836 0.0024150522069324113 0.004417734221194269 0.011631704351645743 0.03120018942994704 0.0030614079635093955 0.0030614079635083876 0.0030614079635079786 0.007257847304341025 0.008878083094172855 0.19361248343905793 1.2676363495251204 0.692981472 0.623971095286146 0.2845522176750427 -P41807 YPR036W VMA13 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.07358058551073342 0.09884914840315177 0.0762187936928307 0.07357792344941592 0.0657821444996866 +P32288 YPR035W GLN1 0.01581203809347923 0.002415052206932297 0.004417734221194465 0.012753509241336706 0.031200189429948493 0.0030614079635115005 0.0030614079635082423 0.003061407963508114 0.00795782113005885 0.00887808309417327 0.19361248343905793 1.2676363495251204 0.692981472 0.623971095286146 0.2845522176750427 +P41807 YPR036W VMA13 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.14875586730085508 0.1915307291816694 0.17650859014517292 0.14566734727160305 0.11168470761239206 P08425 YPR047W MSF1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0159464039314012 0.011812636947342295 0.011583862922574033 0.006479775061534607 0.01045617415049068 -P32331 YPR058W YMC1 0.01570249693355325 0.00760936760595773 0.010969030356534714 0.011218100829847503 0.06829444944572305 0.00015754712346772046 0.00015754712346884242 0.0001575471234642952 0.00015754712379911336 0.0004376493257528227 0.010033252936421355 0.02070436488644489 0.014362903405626709 0.014044010317676475 0.006408270793670342 -P32178 YPR060C ARO7 0.08119413983705334 0.08541676579646522 0.09871890346928908 0.14457739232387046 0.28154708687918667 0.0006633828635753932 0.0009492871630434663 0.0008980439490849943 0.001639431558247299 0.0019238103043686396 0.008170329347742596 0.011113592913427195 0.00909698059363444 0.011339473840936198 0.006832996660321181 +P32331 YPR058W YMC1 0.015702496979461824 0.007609367605846571 0.010969030356843174 0.011218100803387665 0.06829444944466358 0.0001575471239283328 0.00015754712346654096 0.00015754712346872557 0.00015754712342751112 0.0004376493257460333 0.010033252936421355 0.02070436488644489 0.014362903405626709 0.014044010317676475 0.006408270793670342 +P32178 YPR060C ARO7 0.08119413983705333 0.05969112498028506 0.07292341197688419 0.05850208509503678 0.28154708687918667 0.0006633828635753931 0.0006633828635753931 0.0006633828635753248 0.0006633828635753931 0.0019238103043686396 0.008170329347742596 0.011113592913427195 0.00909698059363444 0.011339473840936198 0.006832996660321181 Q12178 YPR062W FCY1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.036072088792233524 0.031238959079778316 0.014463470102758398 0.014007007234463765 0.03495007395243795 Q12074 YPR069C SPE3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3985524579377695 0.7943486705424473 0.39942066237045254 0.39383654228094556 0.27221727359175774 -P23254 YPR074C TKL1 0.04209542351923485 0.011209363991289616 0.019563318982665216 0.034043078715666336 0.019717691512918304 0.05198086375735959 0.013650899831593632 0.012985714035027681 0.022609668044719117 0.028824808995667098 1.234834084365673 1.2178121650970781 0.6637786791972334 0.664148746168317 1.4618754420000002 +P23254 YPR074C TKL1 0.04208119751669878 0.008161841040616378 0.015725181142068945 0.015686777011357504 0.019717691512919067 0.051963297004543774 0.009939589308851221 0.010438039968619767 0.010418353283515066 0.028824808995668215 1.234834084365673 1.2178121650970781 0.6637786791972334 0.664148746168317 1.4618754420000002 Q06817 YPR081C GRS2 3.520490091298191e-05 3.520490091298191e-05 3.520490091298191e-05 3.520490091298191e-05 0.00010209421264764754 0.03520490091298191 0.03520490091298191 0.03520490091298191 0.03520490091298191 0.10209421264764754 1000.0 1000.0 1000.0 1000.0 1000.0 -P06197 YPR113W PIS1 9.015544945121599e-07 9.015544945121599e-07 8.693384417664731e-07 0.04946900485700612 2.520589749159035e-06 0.0009015544945121599 0.0009015544945121599 0.0008693384417664731 0.0008693384417634499 0.0025205897491590353 1000.0 1000.0 1000.0 0.01757339660007995 1000.0 -Q06489 YPR118W MRI1 0.00025373466455581915 0.03145701965109787 0.032655154973268576 0.03242685704249764 0.047553306175850636 1.827735101554447e-05 0.0023459917158453534 0.0012785840608262322 0.0011829784426357587 0.0017634994122214624 0.07203332287111928 0.07457768542174899 0.039154126258867175 0.03648144009409804 0.03708468567253972 +P06197 YPR113W PIS1 9.004387985554808e-07 9.015544945121599e-07 8.693384417634557e-07 0.049469004857006 2.5205897491575486e-06 0.0009004387985554808 0.0009015544945121599 0.0008693384417634557 0.0008693384417634476 0.0025205897491575487 1000.0 1000.0 1000.0 0.01757339660007995 1000.0 +Q06489 YPR118W MRI1 0.00025373466529765 0.03145701965109787 0.032655154973268576 0.03242685704249764 0.047553306174752244 1.827735106898101e-05 0.0023459917158453534 0.0012785840608262322 0.0011829784426357587 0.001763499412180729 0.07203332287111928 0.07457768542174899 0.039154126258867175 0.03648144009409804 0.03708468567253972 Q06490 YPR121W THI22 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q06494 YPR127W YPR127W 0.0 1.0 1.0 1.0 0.0 0.0 0.048799716576974864 0.026242498659583204 0.022880897817638367 0.0 0.04565433646208004 0.048799716576974864 0.026242498659583204 0.022880897817638367 0.0035947661892659377 +Q06494 YPR127W YPR127W 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.026242498659583204 0.0 0.0 0.04565433646208004 0.048799716576974864 0.026242498659583204 0.022880897817638367 0.0035947661892659377 Q06497 YPR128C ANT1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 0.002021490213675111 0.0012748578161235092 0.0012463245670734633 1000.0 P53390 YPR138C MEP3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -Q06508 YPR139C LOA1 1.0 1.0 1.0 7.649256845207125e-05 0.00022183897630168153 0.009316760685582735 0.017368908191782977 0.0096245806999186 0.07649256845207125 0.22183897630168153 0.009316760685582735 0.017368908191782977 0.0096245806999186 1000.0 1000.0 -Q06510 YPR140W TAZ1 0.0 0.0 2.5465307204479294e-08 2.546530727974361e-08 0.0 0.0 0.0 2.5465307204479294e-05 2.5465307279743613e-05 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +Q06508 YPR139C LOA1 1.0 1.0 1.0 7.649256845162067e-05 0.00022183897630168175 0.009316760685582735 0.017368908191782977 0.0096245806999186 0.07649256845162067 0.22183897630168176 0.009316760685582735 0.017368908191782977 0.0096245806999186 1000.0 1000.0 +Q06510 YPR140W TAZ1 0.0 0.0 2.546530728010196e-08 2.546530728049657e-08 0.0 0.0 0.0 2.5465307280101958e-05 2.546530728049657e-05 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P49089 YPR145W ASN1 0.11507966813615596 0.053755323557941555 0.1249682305221405 0.143104433147348 0.38818588462454745 0.037310924594639916 0.037310924594639916 0.037310924594639916 0.037310924594639916 0.10820168132445575 0.3242182150759739 0.6940879921301818 0.29856327835280966 0.26072514857888845 0.2787367743397166 Q06451 YPR156C TPO3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 0.013313288459977311 1000.0 1000.0 P32486 YPR159W KRE6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 P06738 YPR160W GPH1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.19639990837002338 0.2719314292914735 0.21943703156876215 0.15869300129865757 0.1197274294497957 P06780 YPR165W RHO1 0.3803363326352806 0.2726152000465546 0.32678213521426264 0.4576684530925227 0.9900990099009902 0.0914294990677141 0.0914294990677141 0.0914294990677141 0.0914294990677141 0.26514554729637085 0.2403911780770874 0.33537931506423946 0.27978732377082405 0.1997723427295755 0.26779700276933455 -P18408 YPR167C MET16 0.9900990099009948 0.9900990099010027 1.0 1.0 0.9900990099009949 0.028752298946062068 0.02875229894606242 0.029039821935522753 0.029039821935522625 0.08338166694357992 0.029039821935522552 0.02903982193552267 0.029039821935522753 0.029039821935522625 0.08421548361301531 -P0C5R9 YPR170W-B YPR170W__45__B 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 +P18408 YPR167C MET16 0.9900990099056053 0.9900990099009849 1.0 0.9900990099005923 0.9900990099041457 0.02875229894619601 0.02875229894606173 0.02903982193571583 0.02875229894605039 0.0833816669435779 0.029039821935522604 0.029039821935522504 0.02903982193571583 0.029039821935522563 0.08421548361274528 +P0C5R9 YPR170W-B YPR170W__45__B 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.025589967542695245 0.0329483820175979 0.030364174366895102 0.02505865991269987 0.019212741619369342 P14020 YPR183W DPM1 0.04899840330553012 0.05709020135422312 0.10498854564746421 0.11720457270023528 0.16934293567581635 0.008351096411220811 0.008351096411220811 0.008351096411220811 0.008351096411220811 0.02421817959254035 0.1704360927670939 0.14627897980960716 0.07954292879970488 0.07125230883764015 0.14301263584388726 Q06625 YPR184W GDB1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.06844163366351425 0.07762117990777304 0.0438088693444764 0.03132050213906149 1000.0 -P07257 YPR191W QCR2 0.5821562574079976 0.9338617272706928 0.9999999999999836 1.0000000000000397 1.000000000000396 0.20708097502489073 0.28741519452136394 0.37495870702505174 0.461690110705127 0.6196790613551649 0.3557137321634256 0.30777061113893645 0.3749587070250579 0.4616901107051087 0.6196790613549196 +P07257 YPR191W QCR2 0.20484506483564066 0.3048373008509113 0.42083839854540595 0.8923597466162239 0.6186205673623892 0.04142881363079979 0.05867308871578719 0.07496903970829663 0.09367469346942149 0.11477814799722108 0.20224462651341188 0.1924734556827834 0.17814210862749474 0.10497413607531096 0.18553884893708003 P0CD91 YPR192W AQY1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 Q06592 YPR193C HPA2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1000.0 1000.0 1000.0 1000.0 1000.0 -standard standard standard 9.157844356779493e-05 0.00027259010951337544 0.00014803505467485205 0.00029863344595108533 0.00020702899530090674 0.09157844356779493 0.2725901095133754 0.14803505467485206 0.2986334459510853 0.20702899530090674 1000.0 1000.0 1000.0 1000.0 1000.0 +standard standard standard 9.157844356762445e-05 9.768188790085282e-05 0.00015328147159975243 0.0001313722251344529 0.0002091964660418793 0.09157844356762446 0.09768188790085282 0.15328147159975242 0.1313722251344529 0.2091964660418793 1000.0 1000.0 1000.0 1000.0 1000.0 P14126 YOR063W YOR063W 0.15017087316889202 0.19305101431846675 0.295944285391921 0.3251778959337587 0.43344861802617474 0.48515937051329927 0.48515937051329927 0.48515937051329927 0.48515937051329927 1.4069621744885676 3.2307155194313695 2.5131148480419574 1.6393604960839145 1.4919813941232036 3.2459722236410617 P26783 YJR123W YJR123W 0.2896651006563543 0.32367530017087504 0.5690479184399285 0.5877639013210619 0.8091537749578586 0.27761564692816165 0.27761564692816165 0.27761564692816165 0.27761564692816165 0.8050853760916687 0.9584021212742242 0.8576979670107743 0.48785987599999997 0.4723251058872295 0.9949720325207632 P05755 YBR189W YBR189W 0.268176545496891 0.2962511160786947 0.4354965589682856 0.5182313863281959 0.7040933731587714 0.24723636370666072 0.24723636370666072 0.24723636370666072 0.24723636370666072 0.716985454749316 0.921916431015877 0.8345499823905678 0.5677114057855629 0.4770771709880303 1.0183101873728861 diff --git a/results/enzymeUsage/selectedSystemUsage.pdf b/results/enzymeUsage/selectedSystemUsage.pdf index eed5c51..20557c4 100644 Binary files a/results/enzymeUsage/selectedSystemUsage.pdf and b/results/enzymeUsage/selectedSystemUsage.pdf differ diff --git a/results/enzymeUsage/supplementSystemUsage.pdf b/results/enzymeUsage/supplementSystemUsage.pdf index f5073b7..cae738f 100644 Binary files a/results/enzymeUsage/supplementSystemUsage.pdf and b/results/enzymeUsage/supplementSystemUsage.pdf differ diff --git a/results/enzymeUsage/systemMedians.tsv b/results/enzymeUsage/systemMedians.tsv index 814e695..1181e9a 100644 --- a/results/enzymeUsage/systemMedians.tsv +++ b/results/enzymeUsage/systemMedians.tsv @@ -1,9 +1,9 @@ GOterm CN4 CN22 CN38 CN75 hGR -Amino acid metabolism 1.3 2.02 3.12 5.46 7.79 -ETC 40.64 66.17 100.0 100.0 100.0 -Glycolysis 1.68 2.99 5.77 11.4 28.36 +Amino acid metabolism 1.37 2.1 3.39 5.1 7.94 +ETC 20.48 32.95 53.89 89.53 70.83 +Glycolysis 1.68 3.11 5.71 11.46 30.16 Nitrogen metabolism 0.94 7.08 0.06 0.07 0.11 -PP shunt 11.0 0.83 0.03 0.2 1.84 -Ribosome 26.28 29.0 47.31 57.26 74.03 -TCA cycle 3.66 7.3 3.91 6.37 0.05 -THF cycle 4.03 5.95 18.67 16.87 17.97 +PP shunt 11.0 0.85 0.01 0.01 2.15 +Ribosome 26.2 28.37 47.13 56.73 73.79 +TCA cycle 1.09 7.72 16.74 46.39 2.25 +THF cycle 4.91 9.21 13.02 12.82 16.96 diff --git a/results/modelGeneration/average_riboSubunit_abundance.pdf b/results/modelGeneration/average_riboSubunit_abundance.pdf index efb6526..eef8d64 100644 Binary files a/results/modelGeneration/average_riboSubunit_abundance.pdf and b/results/modelGeneration/average_riboSubunit_abundance.pdf differ diff --git a/results/modelGeneration/minimumUsage_CN22.tsv b/results/modelGeneration/minimumUsage_CN22.tsv index 8588285..e73c382 100644 --- a/results/modelGeneration/minimumUsage_CN22.tsv +++ b/results/modelGeneration/minimumUsage_CN22.tsv @@ -1,29 +1,12 @@ protein measured_mg_gDW required_mg_gDW fold_change -P00856 0.04587696573253659 0.1136383964790469 2.477025118477985 -P00854 0.22929814940760604 0.5679772757031657 2.4770251184780183 -P61829 0.6114039455835648 1.5144629307470612 2.4770251184780245 -P07251 1.3854812131496934 3.431871766151226 2.477025118478046 -P38077 0.2706835537407016 0.6704899617746061 2.4770251184779952 -Q12165 0.13411644740085416 0.3322098090129518 2.477025118478019 -P48445 0.02378783337428263 0.31189417544253406 13.111499922465715 -P13663 0.42385502360956856 0.9455892011159087 2.2309260205605876 -P09457 0.17977277502955855 0.44530167936670645 2.4770251184779744 -P81449 0.08570214347424733 0.21228636209311688 2.47702511847801 -Q06405 0.08913779394820576 0.22079655461542277 2.4770251184780094 +P48445 0.02378783337428263 0.3118941754425341 13.111499922465718 +P13663 0.42385502360956856 0.9455892011159096 2.23092602056059 P38972 0.460011122486212 1.1642282779337183 2.5308698442799367 -P05374 0.046407857493222064 0.5802740778505086 12.503789426936127 +P05374 0.046407857493222064 0.5802740778505087 12.503789426936128 P32476 0.08428851148026975 0.6002879186421042 7.121823699337952 P38604 0.07023654273488282 0.09105203330411445 1.2963626875514427 -P00830 1.2953190280051239 3.2085377688112184 2.4770251184780143 -P30902 0.15610145846127618 0.38666723363963323 2.477025118478013 Q12452 0.03539720662601935 0.11260316317060194 3.181131335031137 -Q12349 0.11132768324790054 0.27576146778701305 2.4770251184780085 -P81450 0.05270098708677512 0.13054166878252996 2.477025118478062 P24521 0.020056871599999998 0.09212045895770378 4.592962491603316 Q12362 0.008407664000490724 0.01899729462493805 2.259521149254924 -P81451 0.05936740979541922 0.14705456528223146 2.47702511847802 -P13188 0.21118839080000001 0.21912741745994718 1.037592154710178 -P05626 0.21216717663149223 0.5255434258325733 2.4770251184770973 -P21306 0.05313438336215978 0.13161520224286227 2.477025118477115 -Q12233 0.1018166049862771 0.2522022880290708 2.4770251184771164 -P18408 0.022533577685585133 0.02903982193552267 1.2887355190871275 +P13188 0.21118839080000001 0.21912741745994715 1.037592154710178 +P18408 0.022533577685585133 0.029039821935522504 1.2887355190871201 diff --git a/results/modelGeneration/minimumUsage_CN38.tsv b/results/modelGeneration/minimumUsage_CN38.tsv index 10a931e..6dbbd17 100644 --- a/results/modelGeneration/minimumUsage_CN38.tsv +++ b/results/modelGeneration/minimumUsage_CN38.tsv @@ -1,36 +1,19 @@ protein measured_mg_gDW required_mg_gDW fold_change -P00856 0.034235299233212266 0.09585341403582083 2.799841572374275 -P00854 0.171111812502103 0.47908596616768556 2.7998415723741896 -P61829 0.4562550442296358 1.2774418404395478 2.799841572374165 -P07251 1.0339036847097756 2.894766518281301 2.799841572374204 -P38077 0.20199532187565689 0.5655548996125387 2.799841572374036 -Q12165 0.1000832691427813 0.28021729764507297 2.799841572374179 -P13663 0.2424911865362474 0.9455892011159093 3.899478635173255 +P13663 0.2424911865362474 0.9455892011159102 3.899478635173259 P49367 0.23445747886261187 0.2726539365242995 1.1629142215764852 -P09457 0.1341539190495542 0.3756097196518684 2.7998415723742256 -P81449 0.06395450265551642 0.17906247527543434 2.799841572374252 -P07285 0.011862219171716468 0.01288132192250142 1.0859116440214522 -Q06405 0.06651832788150071 0.18624077972744074 2.799841572374158 +P07285 0.011862219171716468 0.012881321922501823 1.0859116440214862 P21147 0.24667091079999998 0.27474046799297513 1.1137935442081124 -P38972 0.26872131869994015 1.1642282779330753 4.3324745634829105 -P05374 0.04315604565335354 0.5802740778505086 13.445951061213993 -P32476 0.07044974659234322 0.6002879186421042 8.520795995415915 +P38972 0.26872131869994015 1.1642282779335165 4.332474563484553 +P05374 0.04315604565335354 0.5802740778505084 13.44595106121399 +P32476 0.07044974659234322 0.6002879186421041 8.520795995415915 P38604 0.02093592504194455 0.09105203330411445 4.3490809754856405 -P00830 0.9666209135269491 2.7063854184190577 2.799841572374178 -P30902 0.11648939845584592 0.3261518605375327 2.799841572374134 -P36148 0.02540187482765399 0.027107482089064605 1.0671449360719545 +P36148 0.02540187482765399 0.027107482089067686 1.0671449360720757 Q12452 0.02438189480357763 0.11260316317060194 4.618310597996647 -Q12349 0.08307734585483044 0.2326034066468608 2.799841572374165 -P81450 0.03932766768665813 0.11011123893362372 2.7998415723742203 P24521 0.014787597783157297 0.09212045895770384 6.229575642274145 -P32462 0.010687994144126819 0.015622718902897162 1.461707285036457 -P37254 0.005816436929293343 0.00926442275107468 1.5928003455889348 +P32462 0.010687994144126819 0.015622718902897164 1.461707285036457 +P37254 0.005816436929293343 0.009264422751081016 1.5928003455900241 Q12362 0.005229192743580213 0.01899729462493805 3.632930656124828 -P81451 0.04430242947836159 0.12403978381069446 2.7998415723742323 -P18544 0.11299929321773239 0.11453413063235787 1.013582716943796 -Q12189 0.010440899651612916 0.018793604131610277 1.7999985402318304 +P18544 0.11299929321773239 0.11453413063235786 1.013582716943796 +Q12189 0.010440899651612916 0.01879360413161099 1.799998540231899 P13188 0.1427926632233914 0.21912741745994718 1.534584568376137 -P05626 0.15832796837070426 0.44329322791384984 2.799841572374229 -P21306 0.039651086006449725 0.11101675899064281 2.7998415723741994 -Q12233 0.07597978381867669 0.21273135739551322 2.7998415723739063 -P18408 0.013210018155733949 0.029039821935522753 2.198318094129016 +P18408 0.013210018155733949 0.02903982193571583 2.198318094143632 diff --git a/results/modelGeneration/minimumUsage_CN4.tsv b/results/modelGeneration/minimumUsage_CN4.tsv index 173a461..d82655d 100644 --- a/results/modelGeneration/minimumUsage_CN4.tsv +++ b/results/modelGeneration/minimumUsage_CN4.tsv @@ -1,27 +1,10 @@ protein measured_mg_gDW required_mg_gDW fold_change -P00856 0.052813207642052516 0.1244097068825561 2.355655193787072 -P00854 0.263966253723134 0.6218134765674198 2.355655193787084 -P61829 0.7038434869369382 1.6580125656162124 2.3556551937870873 -P07251 1.5949552422631814 3.7571646002951993 2.3556551937870833 -P38077 0.31160881066852386 0.7340429132811227 2.355655193787079 -Q12165 0.15439381553894432 0.3636985934629174 2.355655193787072 -P13663 0.7361453964669016 0.9455892011159078 1.2845141811036553 -P09457 0.20695302630466955 0.4875099712845447 2.3556551937870593 -P81449 0.09865964381912799 0.23240810237971102 2.355655193787068 -Q06405 0.10261473803622433 0.24172494061412905 2.355655193787047 -P21147 0.10995969167417075 0.274740467992975 2.4985561873625266 -P38972 0.48791523408390125 1.1642282779333764 2.386128156296053 -P05374 0.030510116372361774 0.5802740778505087 19.019071273558367 +P13663 0.7361453964669016 0.9455892011159084 1.2845141811036562 +P21147 0.10995969167417075 0.27474046799297513 2.4985561873625275 +P38972 0.48791523408390125 1.1642282779333144 2.386128156295926 +P05374 0.030510116372361774 0.5802740778505084 19.01907127355836 P32476 0.08762151382824664 0.6002879186421042 6.850919282435277 -P00830 1.4911612330154376 3.512661703326766 2.355655193787083 -P30902 0.17970279000155623 0.4233178106051971 2.355655193787092 Q12452 0.01815788570190743 0.11260316317060194 6.201336709525235 -Q12349 0.12815956674114015 0.30189974902726724 2.3556551937870687 -P81450 0.06066896817417507 0.14291516998119808 2.355655193787072 -P24521 0.020461367692783238 0.09212045895770378 4.502165267778988 +P24521 0.020461367692783238 0.09212045895770381 4.502165267778989 Q12362 0.01060375823236004 0.01899729462493805 1.7915624072758485 -P81451 0.06834330236606384 0.16099325517917626 2.355655193787038 -P05626 0.24424521053972242 0.5753574987655143 2.355655193787073 -P21306 0.06116789060981795 0.14409045920801802 2.355655193787087 -Q12233 0.1172104871080317 0.2761074927219503 2.355655193783683 -P18408 0.018904152205782173 0.029039821935522552 1.5361610306248066 +P18408 0.018904152205782173 0.029039821935522604 1.5361610306248092 diff --git a/results/modelGeneration/minimumUsage_CN75.tsv b/results/modelGeneration/minimumUsage_CN75.tsv index e1af5ce..8e1c7a6 100644 --- a/results/modelGeneration/minimumUsage_CN75.tsv +++ b/results/modelGeneration/minimumUsage_CN75.tsv @@ -1,36 +1,19 @@ protein measured_mg_gDW required_mg_gDW fold_change -P00856 0.02452957253306645 0.06124939214474812 2.496961252063503 -P00854 0.12260151685669884 0.30613123703538914 2.496961252063517 -P61829 0.3269064810787747 0.8162728163021216 2.496961252063474 -P07251 0.7407914051964747 1.8497274346372068 2.496961252063416 -P38077 0.14472953385148843 0.3613840380563813 2.4969612520635143 -Q12165 0.07170960572188097 0.1790561068882825 2.496961252063426 -P48445 0.02109786836862816 0.3118941754425341 14.78320795224557 -P13663 0.20091471230824523 0.9455892011159095 4.706420899954692 +P48445 0.02109786836862816 0.31189417544253417 14.783207952245572 +P13663 0.20091471230824523 0.9455892011159093 4.706420899954691 P49367 0.20194338197220035 0.2726539365242995 1.3501503929543637 -P09457 0.09612120710569874 0.24001092964449416 2.496961252063434 -P81449 0.04582336497245461 0.11441916677538098 2.496961252063456 -P07285 0.009244327460804159 0.012881321922503405 1.3934298603246218 -Q06405 0.04766034429646989 0.11900603296828778 2.4969612520634334 +P07285 0.009244327460804159 0.01288132192250084 1.3934298603243445 P21147 0.1823386311260891 0.27474046799297513 1.5067595182448703 -P38972 0.2520049564394557 1.1642282779329152 4.619862618506162 -P05374 0.04040305460465225 0.5802740778505084 14.36213384182324 +P38972 0.2520049564394557 1.1642282779336932 4.6198626185092495 +P05374 0.04040305460465225 0.5802740778505087 14.362133841823246 P32476 0.05126590884789451 0.6002879186421042 11.709300237379054 -P05375 0.007017944940143651 0.008413979548481082 1.1989235624166716 -P00830 0.6925833377070645 1.7293537580793068 2.4969612520634383 -P30902 0.08346458809344666 0.2084078423887717 2.496961252063438 -P36148 0.022843478915760454 0.027107482089066832 1.1866617247325015 +P05375 0.007017944940143651 0.00841397954848108 1.1989235624166714 +P36148 0.022843478915760454 0.027107482089068033 1.186661724732554 Q12452 0.022758014588502105 0.11260316317060194 4.947846515024723 -Q12349 0.05952487130662364 0.14863129718670356 2.4969612520634645 -P81450 0.028178251649115155 0.07036000251873406 2.496961252063468 P24521 0.013013033144246467 0.09212045895770384 7.079092010031006 P37254 0.004547940423039477 0.009264422751075948 2.037058951815458 Q12362 0.004188874821549507 0.01899729462493805 4.5351784033285485 -P81451 0.03174266565855765 0.07926020618662247 2.496961252063415 P18544 0.1029409412 0.11453413063235787 1.1126198118767334 -Q12189 0.007980294919594736 0.01879360413161142 2.3550012024575424 +Q12189 0.007980294919594736 0.01879360413161049 2.3550012024574256 P13188 0.12290499855864723 0.21912741745994718 1.7829007772648482 -P05626 0.1134418997686043 0.2832600280826759 2.496961252063497 -P21306 0.02840998069228222 0.07093862096050044 2.496961252063485 -Q12233 0.054439472122939134 0.13593325247377347 2.496961252063562 -P18408 0.012768184695667952 0.029039821935522625 2.274389243866075 +P18408 0.012768184695667952 0.029039821935522563 2.27438924386607 diff --git a/results/modelGeneration/minimumUsage_hGR.tsv b/results/modelGeneration/minimumUsage_hGR.tsv index 132b4c2..bc47d72 100644 --- a/results/modelGeneration/minimumUsage_hGR.tsv +++ b/results/modelGeneration/minimumUsage_hGR.tsv @@ -1,56 +1,25 @@ protein measured_mg_gDW required_mg_gDW fold_change -P00401 0.19586188934521737 0.27961048753338874 1.4275900659804208 -P00856 0.04674364724513464 0.2872915858737157 6.14610974550384 -P00854 0.23362991947546768 1.435915124929442 6.146109745503808 -P00163 0.3570031572836162 0.4801925257421121 1.345065207254259 -P61829 0.6229542407677768 3.8287451301857818 6.1461097455038445 -P00410 0.09515947129026199 0.1358487158979252 1.427590065980401 -P00420 0.10113212967313173 0.14437522367280708 1.4275900659804255 -P07256 0.41074662323716044 0.5524809919134764 1.3450652072542546 -P07251 1.4116549352848768 8.676186155043027 6.146109745503877 -P38077 0.27579715330086224 1.6950795716846534 6.146109745503867 P20049 0.010330203772919907 0.019380760284347577 1.8761256515726472 -Q12165 0.13665009895434413 0.839866504907362 6.146109745503866 -P07255 0.023194434088076952 0.0331121436901765 1.4275900659804297 -P13663 0.48698436 2.7422086832361363 5.630999490899741 +P13663 0.48698436 2.742208683236135 5.630999490899739 P49367 0.34963281943367314 0.7906964159204685 2.261505133303045 -P09457 0.1831689399262284 1.1257764067541924 6.1461097455038 -P81449 0.08732117956683001 0.5366855527245878 6.146109745503876 -P07285 0.011107051352484751 0.03735583357525305 3.363253881679065 -Q06405 0.09082173439315751 0.5582003468572905 6.146109745503222 -P00128 0.11910736177927135 0.1602071682571417 1.3450652072542428 -P08067 0.19107061503416925 0.2570024364111305 1.3450652072542428 -P00127 0.14112157516133783 0.18981772074242884 1.345065207254234 +P07285 0.011107051352484751 0.03735583357525457 3.363253881679202 P53199 0.06878598452463883 0.12854257398923422 1.8687320517043824 -P21147 0.19224373976015122 0.7967473571796275 4.144464512465645 +P21147 0.19224373976015122 0.7967473571796279 4.144464512465647 P53045 0.01998105485498398 0.02211135068990451 1.1066157843207742 -P38972 0.4361454300729149 3.376262006007724 7.741138100296683 +P38972 0.4361454300729149 3.376262006007444 7.74113810029604 P05374 0.06420361080462726 1.6827948257664744 26.210283264086957 P32476 0.05486887771053044 1.7408349640621017 31.72718372783485 -P22289 0.061136054697001896 0.08223198008172393 1.3450652072541505 -P37299 0.07027048127492473 0.0945183794599109 1.3450652072542268 -P04801 0.42926462881820737 0.4988488127469354 1.1621009029332272 -P08525 0.08974962550823914 0.12071909863522859 1.345065207254223 -P08524 0.42704179421841565 0.4416959631172679 1.0343155379572924 -P05375 0.008438519483048803 0.024400540690595128 2.8915665525938103 -P00830 1.3197894574801996 8.111570846633313 6.1461097455046225 -P30902 0.15905043832465085 0.9775414490139027 6.146109745504523 -P36148 0.03582292734159357 0.07861169805829706 2.194452097917245 +P04801 0.42926462881820737 0.49884881274693543 1.1621009029332272 +P08524 0.42704179421841565 0.44169596311726794 1.0343155379572924 +P05375 0.008438519483048803 0.024400540690595135 2.8915665525938112 +P36148 0.03582292734159357 0.07861169805829576 2.194452097917209 Q12452 0.015124974633723158 0.32654917319474563 21.590064188713445 -Q12349 0.11343082244576816 0.69715828327444 6.146109745503739 -P81450 0.05369658412495027 0.33002509899062105 6.146109745503791 -P24521 0.011291191391458066 0.2671529531022092 23.66029800046733 -Q00955 1.1477706702247867 2.9653439920280493 2.583568363397278 +P24521 0.011291191391458066 0.26715295310220916 23.660298000467325 +Q00955 1.1477706702247867 2.965343992028046 2.5835683633972755 P22768 0.5732167938049126 0.9318926708816919 1.6257246489516675 -Q12362 0.004688745642588283 0.055092154412320335 11.74987056493607 -P81451 0.06048894509530134 0.371771694945478 6.146109745503836 +Q12362 0.004688745642588283 0.05509215441232033 11.74987056493607 P18544 0.10591934779206906 0.33214897883383776 3.1358669191003847 -P07143 0.2784896124540395 0.3745866882936513 1.3450652072542604 -Q12189 0.04154626420985096 0.05450145198167168 1.311825576094732 +Q12189 0.04154626420985096 0.05450145198167118 1.31182557609472 P13188 0.2792691330382714 0.6354695106338467 2.2754734965527366 -P05626 0.21617531811666957 1.3286372294142705 6.146109745503908 -P21306 0.05413816787597782 0.3327391211862686 6.14610974550381 -Q12233 0.1037400663095817 0.6375978325445247 6.146109745503744 P06780 0.08725786043226363 0.26779700276933455 3.0690301302679717 -P18408 0.029250059279734147 0.08421548361301531 2.87915599786028 -P07257 0.3310146096876997 0.44523623458377254 1.3450652072542564 +P18408 0.029250059279734147 0.08421548361274528 2.879155997851048 diff --git a/results/modelGeneration/modifiedEnzymes_CN22.tsv b/results/modelGeneration/modifiedEnzymes_CN22.tsv index 3e1030a..fbebd2a 100644 --- a/results/modelGeneration/modifiedEnzymes_CN22.tsv +++ b/results/modelGeneration/modifiedEnzymes_CN22.tsv @@ -1,9 +1,6 @@ protein previous_mg_gDW modified_mg_gDW flex_mass_mg_gDW fold_change -P32264 0.012222435849325312 0.018402510797685137 0.006180074948359825 1.505633658015965 -Q12482 0.002572137794239356 0.132261385726227 0.12968924793198766 51.42080102490774 -P33330 0.26664675317123787 0.3606182043512232 0.09397145117998534 1.3524192590473352 -P38698 0.02918915828377166 0.061719947569001836 0.03253078928523018 2.11448192404083 -Q12189 0.026336479661299296 0.07949948270889251 0.053163003047593214 3.018607032196286 -P16451 0.026423093498594525 0.17687242710184317 0.15044933360324864 6.693857670800401 -P38858 0.1161883700186846 0.2920518433282457 0.1758634733095611 2.513606510542148 -P12695 0.44490724002344134 1.0102261174070046 0.5653188773835633 2.2706443647754027 +P32264 0.012222435849325312 0.08897571218087687 0.07675327633155156 7.279703757724235 +P07275 0.3850147942259282 0.8227669200686503 0.43775212584272205 2.136974818650338 +P38698 0.02918915828377166 0.03803438152595025 0.008845223242178589 1.3030311171081723 +P09368 0.01808583679762115 0.03045736239967182 0.012371525602050671 1.684044965156266 +P33330 0.26664675317123787 0.35064809194701 0.08400133877577215 1.3150285453572628 diff --git a/results/modelGeneration/modifiedEnzymes_CN38.tsv b/results/modelGeneration/modifiedEnzymes_CN38.tsv index 91542a3..50e8be5 100644 --- a/results/modelGeneration/modifiedEnzymes_CN38.tsv +++ b/results/modelGeneration/modifiedEnzymes_CN38.tsv @@ -1,14 +1,9 @@ protein previous_mg_gDW modified_mg_gDW flex_mass_mg_gDW fold_change -P33330 0.1744484494884965 0.36168954975082773 0.18724110026233123 2.073331983238282 -P16451 0.015830710004432248 0.14585109868658877 0.1300203886821565 9.213174813116638 -Q99297 0.03806399419702313 0.012853100756261216 -0.025210893440761915 0.3376708363744554 -P32264 0.006486823808271518 0.018402510797685137 0.011915686989413619 2.8369062181432483 -P38698 0.017732073600000002 0.051462692534841856 0.033730618934841854 2.902237701903169 -Q12189 0.018793604131610277 0.10540504830977569 0.08661144417816541 5.608559570140544 -P49367 0.2726539365242995 0.5449522513663239 0.2722983148420244 1.9986957031069919 -P38858 0.03548572479999999 0.40771460977055796 0.37222888497055795 11.489538738984924 -P07285 0.01288132192250142 0.026776392663392688 0.013895070740891267 2.078699129211188 -P38152 0.012772141853097618 0.07838269195536683 0.06561055010226921 6.1370044943837465 -P00856 0.09585341403582083 0.09585341403581842 -2.4147350785597155e-15 0.9999999999999748 -P12695 0.27987830685118037 0.8330444239387215 0.553166117087541 2.9764522778168585 -P05374 0.5802740778505086 0.5882874785015605 0.008013400651051938 1.0138096822810623 +P49367 0.2726539365242995 0.3495680924942362 0.07691415596993673 1.282094426914984 +P05374 0.5802740778505084 0.588276790101759 0.008002712251250599 1.0137912627096748 +P38698 0.017732073600000002 0.03865113268489674 0.02091905908489674 2.1797299941782744 +Q02046 0.06622996754243687 0.07830280654394603 0.012072839001509156 1.182286651337606 +P18544 0.11453413063235786 0.18136048576115663 0.06682635512879877 1.5834623684646818 +Q12189 0.01879360413161099 0.019101433407158478 0.00030782927554748665 1.016379470025641 +P33330 0.1744484494884965 0.35619373942199145 0.18174528993349495 2.0418280613349884 +Q99297 0.03806399419702313 0.07250998296002337 0.034445988763000236 1.9049494013871553 diff --git a/results/modelGeneration/modifiedEnzymes_CN4.tsv b/results/modelGeneration/modifiedEnzymes_CN4.tsv index 0c7b293..0d7d6c0 100644 --- a/results/modelGeneration/modifiedEnzymes_CN4.tsv +++ b/results/modelGeneration/modifiedEnzymes_CN4.tsv @@ -1,24 +1,13 @@ protein previous_mg_gDW modified_mg_gDW flex_mass_mg_gDW fold_change -Q12482 0.005247130672104108 0.1390102347043028 0.13376310403219868 26.49261918391666 -P38698 0.026039691049912786 0.0593683930489064 0.03332870199899361 2.2799192561505155 -P16451 0.0306451097874405 0.19366722750170928 0.16302211771426878 6.319678044719595 -P00856 0.1244097068825561 0.12646815454294832 0.002058447660392218 1.0165457158607039 -P12695 0.47461200059426184 1.106151447762838 0.6315394471685762 2.3306436549809644 -P33330 0.3453844651148362 0.3605448676922514 0.015160402577415188 1.0438942804575027 -P07251 3.7571646002951993 3.8193295782135595 0.062164977918360176 1.0165457158606988 -P00830 3.512661703326766 3.5707812057847703 0.058119502458004124 1.0165457158606992 -P81451 0.16099325517917626 0.16365700383486304 0.002663748655686776 1.0165457158607183 -P61829 1.6580125656162124 1.6854455704203641 0.027433004804151784 1.0165457158606974 -P38077 0.7340429132811227 0.7461881787538334 0.012145265472710665 1.016545715860701 -P00854 0.6218134765674198 0.6321018256690576 0.010288349101637784 1.0165457158606988 -P21306 0.14409045920801802 0.14647453900431132 0.0023840797962932925 1.0165457158606974 -P81450 0.14291516998119808 0.14527980377589114 0.0023646337946930662 1.0165457158607036 -P05626 0.5753574987655143 0.5848772004584135 0.009519701692899174 1.0165457158607034 -P81449 0.23240810237971102 0.2362534608054115 0.003845358425700496 1.0165457158607056 -P09457 0.4875099712845447 0.4955761727486814 0.008066201464136669 1.0165457158607094 -P30902 0.4233178106051971 0.43032190681824223 0.007004096213045152 1.0165457158606952 -Q12165 0.3636985934629174 0.3697162470492924 0.006017653586375016 1.0165457158607036 -Q12349 0.30189974902726724 0.30689489649309065 0.004995147465823413 1.0165457158607054 -Q12233 0.2761074927219503 0.28067588884394284 0.004568396121992557 1.0165457158621665 -Q06405 0.24172494061412905 0.24572445279797858 0.0039995121838495296 1.0165457158607147 -P28239 0.006707538790964384 0.019148418136993584 0.0124408793460292 2.8547607004208615 +P32473 0.3128939764878944 0.3580376305046368 0.04514365401674236 1.1442777982608079 +P16387 0.3620224085579091 0.4142542045857189 0.05223179602780975 1.1442777982608079 +P16451 0.17717951467323947 0.20274258494721298 0.025563070273973504 1.1442777982608079 +P12695 1.0119800814930915 1.1579863395347076 0.14600625804161615 1.1442777982608079 +P32264 0.02105500328 0.08752024352197224 0.06646524024197224 4.156743286053396 +P05374 0.5802740778505084 0.5845578504477592 0.004283772597250768 1.007382326319175 +P07275 0.16772672858819115 0.8057981178568774 0.6380713892686862 4.804232006666646 +P38858 0.08949454986540485 0.21633752869964423 0.1268429788342394 2.417326295567771 +P38698 0.026039691049912786 0.035250426149960525 0.009210735100047739 1.353719062272768 +P28239 0.006707538790964384 0.02186314027420716 0.015155601483242777 3.259487713087644 +Q12189 0.07555817722670258 0.07578418269688636 0.00022600547018378214 1.0029911450815665 +P33330 0.3453844651148362 0.36126857514858907 0.01588411003375284 1.045989648169241 diff --git a/results/modelGeneration/modifiedEnzymes_CN75.tsv b/results/modelGeneration/modifiedEnzymes_CN75.tsv index 6a4d684..49b7ad8 100644 --- a/results/modelGeneration/modifiedEnzymes_CN75.tsv +++ b/results/modelGeneration/modifiedEnzymes_CN75.tsv @@ -1,12 +1,10 @@ protein previous_mg_gDW modified_mg_gDW flex_mass_mg_gDW fold_change -P16451 0.012415452765071642 0.04431382578322126 0.031898373018149614 3.569247664321129 -P33330 0.15976919798682934 0.3616895497499544 0.20192035176312503 2.2638252823912306 -P32264 0.005750759849711341 0.018402510797685137 0.012651750947973796 3.2000137857623896 -P49367 0.2726539365242995 0.5449522513663239 0.2722983148420244 1.9986957031069919 -P07285 0.012881321922503405 0.03206238581894155 0.019181063896438148 2.4890602076273884 -P00856 0.06124939214474812 0.061249392144745986 -2.1371793224034263e-15 0.9999999999999651 -Q12189 0.01879360413161142 0.12824726425671867 0.10945366012510725 6.823984551265652 -P38858 0.03411327128591647 0.5140328102044597 0.4799195389185432 15.068411525126178 -P27472 0.04485511016531227 0.06460302271174691 0.01974791254643464 1.4402600389042464 -P05375 0.008413979548481082 0.008530173932764968 0.00011619438428388598 1.013809682281063 -P05374 0.5802740778505084 0.588287478501561 0.008013400651052605 1.0138096822810634 +P49367 0.2726539365242995 0.37736103598279236 0.10470709945849288 1.3840292965994319 +P05374 0.5802740778505087 0.5882767901017554 0.008002712251246713 1.013791262709668 +P38698 0.018554106585468057 0.019802643436024628 0.001248536850556571 1.0672916717819467 +P05375 0.00841397954848108 0.008530018950867958 0.00011603940238687736 1.0137912627096681 +Q02046 0.05988304705825437 0.07864374572756741 0.018760698669313042 1.3132889789502962 +P27472 0.04485511016531227 0.0493137773217936 0.004458667156481334 1.0994015428799313 +P18544 0.11453413063235787 0.18555793101899462 0.07102380038663675 1.6201103548305216 +Q12189 0.01879360413161049 0.01906520083565863 0.00027159670404814165 1.0144515496945752 +P33330 0.15976919798682934 0.3566015352790652 0.19683233729223584 2.231979253651019 diff --git a/results/modelGeneration/modifiedEnzymes_hGR.tsv b/results/modelGeneration/modifiedEnzymes_hGR.tsv index 82d288a..1ac049d 100644 --- a/results/modelGeneration/modifiedEnzymes_hGR.tsv +++ b/results/modelGeneration/modifiedEnzymes_hGR.tsv @@ -1,54 +1,17 @@ protein previous_mg_gDW modified_mg_gDW flex_mass_mg_gDW fold_change -P16451 0.015413923384667414 0.46817640950740363 0.45276248612273623 30.37360429422593 -P33330 0.2053005399367211 1.0488996942749669 0.8435991543382457 5.1090936955074 -P27472 0.025410143732918604 0.18734876586406599 0.16193862213114738 7.372991189394864 -P38698 0.016928058663478077 0.15270406476179577 0.1357760060983177 9.020766515374353 -P07285 0.03735583357525305 0.1760104558664265 0.13865462229117345 4.711726095252425 -Q05979 0.026876241690325955 0.06903309464904048 0.04215685295871452 2.5685546157999015 -P32264 0.018532011528914465 0.053367281313286885 0.034835269784372416 2.8797349510613506 -P47125 0.009396792465483174 0.01778474261892163 0.008387950153438455 1.8926397155465065 -P00044 0.05948236179883932 0.2064046023751806 0.1469222405763413 3.4700135659241456 -Q01574 0.06493959567368007 0.06493959567368007 0.0 1.0 -P49367 0.7906964159204685 1.5803615289623387 0.7896651130418703 1.9986957031069912 -P37299 0.0945183794599109 0.10363674382470041 0.009118364364789508 1.0964718652276193 -P07256 0.5524809919134764 0.6057798637061623 0.05329887179268589 1.0964718652275969 -P00163 0.4801925257421121 0.5265175943688026 0.04632506862669056 1.096471865227593 -P07257 0.44523623458377254 0.4881890046009803 0.042952770017207764 1.0964718652275953 -P07143 0.3745866882936513 0.4107237648027665 0.036137076509115185 1.0964718652275922 -P08067 0.2570024364111305 0.28179594081975157 0.024793504408621048 1.0964718652276064 -P00127 0.18981772074242884 0.20812979031570525 0.018312069573276413 1.0964718652276138 -P00128 0.1602071682571417 0.17566265260174113 0.015455484344599424 1.0964718652276064 -P08525 0.12071909863522859 0.13236509524916643 0.011645996613937837 1.0964718652276224 -P22289 0.08223198008172393 0.09016505258157341 0.00793307249984948 1.0964718652276817 -Q12189 0.05450145198167168 0.2568258858989301 0.2023244339172584 4.712276032302739 -P20485 0.05452403402063208 0.07275376181913074 0.018229727798498657 1.3343429760094505 -P00401 0.27961048753338874 0.2993445614507792 0.01973407391739046 1.07057701623239 -P00420 0.14437522367280708 0.15456479617751717 0.010189572504710087 1.0705770162323862 -P00410 0.1358487158979252 0.1454365129250044 0.009587797027079209 1.0705770162324049 -P07255 0.0331121436901765 0.0354490999928871 0.002336956302710594 1.0705770162323833 -P12695 0.2950317924047663 2.674040517156942 2.3790087247521754 9.063567337476346 -P38705 0.003925578898246396 0.28903326096883963 0.2851076820705932 73.62818795922158 -P16387 0.36480266410446566 0.9566024137296242 0.5917997496251586 2.622246238464118 -P00937 0.08643967594282718 0.09689906055209432 0.010459384609267139 1.1210021265718901 -P81451 0.371771694945478 0.3770924309310249 0.005320735985546887 1.0143118372320603 -P32473 0.6196716319622662 0.8267862045945745 0.20711457263230837 1.3342327806365037 -P09624 0.6010326641431301 0.6909254596856 0.08989279554246998 1.1495639104251127 -P05375 0.024400540690595128 0.024737504405018408 0.0003369637144232801 1.0138096822810634 -P05374 1.6827948257664744 1.706033687654527 0.023238861888052575 1.0138096822810634 -P32332 0.030348657668986128 0.0662477160053423 0.03589905833635616 2.1828878472289763 -P07251 8.676186155043027 8.800358319089 0.12417216404597298 1.0143118372320536 -P00856 0.2872915858737157 0.2914032562888807 0.00411167041516497 1.0143118372320599 -P81450 0.33002509899062105 0.33474836448987183 0.004723265499250784 1.0143118372320676 -P00830 8.111570846633313 8.227662328285604 0.11609148165229044 1.0143118372319306 -P61829 3.8287451301857818 3.8835415072920396 0.05479637710625784 1.0143118372320592 -P38077 1.6950795716846534 1.7193392746099863 0.02425970292533286 1.0143118372320554 -P00854 1.435915124929442 1.4564657084764925 0.020550583547050527 1.014311837232065 -P21306 0.3327391211862686 0.3375012293294267 0.004762108143158139 1.0143118372320648 -P81449 0.5366855527245878 0.5443665089999771 0.007680956275389228 1.014311837232054 -P05626 1.3286372294142705 1.3476524691820873 0.019015239767816716 1.0143118372320483 -P09457 1.1257764067541924 1.141888335447359 0.016111928693166577 1.0143118372320663 -P30902 0.9775414490139027 0.9915318631196713 0.013990414105768623 1.014311837231947 -Q12165 0.839866504907362 0.8518865376222516 0.012020032714889606 1.0143118372320556 -Q12349 0.69715828327444 0.7071358991496576 0.009977615875217616 1.0143118372320765 -Q12233 0.6375978325445247 0.6467230289434261 0.009125196398901414 1.0143118372320756 -Q06405 0.5582003468572905 0.5661892193644483 0.007988872507157851 1.0143118372321618 +P32473 0.20325888685578347 0.5108538039419748 0.3075949170861913 2.513315958009927 +P16387 0.23517318104452922 0.5910645088151729 0.3558913277706437 2.513315958009927 +P16451 0.1150974887096426 0.2892763551008122 0.17417886639116958 2.513315958009927 +P12695 0.6573918334681299 1.6522333857208555 0.9948415522527256 2.5133159580099274 +P07284 0.27566745708392604 0.3016596848897915 0.025992227805865464 1.094288343211844 +P49367 0.7906964159204685 1.1805435772535076 0.3898471613330391 1.4930427828981732 +Q01217 0.45018264581677947 0.6186826830505349 0.1685000372337554 1.3742926094541936 +P23337 0.02901643752090748 0.16282904336395587 0.13381260584304838 5.611613873916506 +P05374 1.6827948257664744 1.706109532523549 0.023314706757074477 1.0138547530572868 +P38698 0.016928058663478077 0.16725781740352613 0.15032975874004806 9.880507902798168 +P05375 0.024400540690595135 0.024738604156327604 0.0003380634657324695 1.0138547530572866 +Q02046 0.07396682372390692 0.23401204348791213 0.1600452197640052 3.1637433068830934 +P20485 0.05452403402063208 0.07273775721295696 0.01821372319232488 1.3340494429563436 +P18544 0.33214897883383776 0.5275408553940657 0.19539187656022794 1.5882657753344336 +Q12189 0.05450145198167118 0.05465727123367742 0.0001558192520062368 1.0028589926752527 +P33330 0.2053005399367211 1.0412658084995001 0.835965268562779 5.071909741788526 diff --git a/results/modelGeneration/relaxedEnzymes_CN22.tsv b/results/modelGeneration/relaxedEnzymes_CN22.tsv index ecf5a42..0c6c2b6 100644 --- a/results/modelGeneration/relaxedEnzymes_CN22.tsv +++ b/results/modelGeneration/relaxedEnzymes_CN22.tsv @@ -1,24 +1,4 @@ protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change -P00856 0.1136383964790469 0.16211070828173524 0.048472311802688337 1.4265487133270651 -P00854 0.5679772757031657 0.8102472518533516 0.24226997615018586 1.4265487133270454 -P61829 1.5144629307470612 2.1604551452387213 0.6459922144916601 1.426548713327042 -P07251 3.431871766151226 4.8957322523063915 1.4638604861551654 1.4265487133270294 -P38077 0.6704899617746061 0.9564865922682732 0.2859966304936671 1.426548713327059 -Q12165 0.3322098090129518 0.47391347560204966 0.1417036665890979 1.426548713327045 -P09457 0.44530167936670645 0.635244537742959 0.18994285837625252 1.426548713327071 -P32264 0.012222435849325312 0.08897571218087687 0.07675327633155156 7.279703757724235 -P81449 0.21228636209311688 0.30283683670081624 0.09055047460769935 1.4265487133270505 -Q06405 0.22079655461542277 0.31497704089367723 0.09418048627825445 1.4265487133270507 -P07275 0.3850147942259282 0.8227669200686503 0.43775212584272205 2.136974818650338 -P38698 0.02918915828377166 0.06323603115175994 0.03404687286798828 2.166421879555101 -P00830 3.2085377688112184 4.57713542575888 1.3685976569476614 1.4265487133270476 -P30902 0.38666723363963323 0.5515996446343481 0.16493241099471484 1.4265487133270487 -Q02046 0.10540202111264188 0.21829984435520183 0.11289782324255995 2.071116303566014 -P09368 0.01808583679762115 0.03045736239967182 0.012371525602050671 1.684044965156266 -Q12349 0.27576146778701305 0.39338716705674254 0.11762569926972949 1.4265487133270511 -P81450 0.13054166878252996 0.18622404963728015 0.05568238085475019 1.4265487133270203 -P81451 0.14705456528223146 0.20978050089223513 0.06272593561000367 1.4265487133270442 -P33330 0.26664675317123787 0.5341221410333665 0.26747538786212866 2.003107612153667 -P05626 0.5255434258325733 0.7497132979192237 0.2241698720866504 1.4265487133275758 -P21306 0.13161520224286227 0.18775549741390252 0.056140295171040244 1.4265487133275656 -Q12233 0.2522022880290708 0.35977884948613886 0.10757656145706807 1.426548713327565 +P38698 0.03803438152595025 0.040445538265238515 0.002411156739288267 1.063394135583437 +Q02046 0.10540202111264188 0.2182998443552095 0.11289782324256761 2.071116303566087 +P33330 0.35064809194701 0.5341221410333745 0.1834740490863645 1.523242684902706 diff --git a/results/modelGeneration/relaxedEnzymes_CN38.tsv b/results/modelGeneration/relaxedEnzymes_CN38.tsv index 9f60992..4019fb6 100644 --- a/results/modelGeneration/relaxedEnzymes_CN38.tsv +++ b/results/modelGeneration/relaxedEnzymes_CN38.tsv @@ -1,48 +1,16 @@ protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change -P00401 0.2019994703676272 0.23052565723081309 0.028526186863185893 1.1412191171158514 -P00856 0.09585341403582083 0.2230351885250394 0.12718177448921858 2.3268361463024174 -P00854 0.47908596616768556 1.1147545432652217 0.6356685770975361 2.326836146302488 -P00163 0.26548093691968927 0.4043973841070687 0.13891644718737944 1.523263360447621 -P61829 1.2774418404395478 2.9723978491339413 1.6949560086943936 2.3268361463025085 -P00410 0.09814141416361112 0.11200085802429736 0.013859443860686244 1.141219117115851 -P00420 0.10430123338142729 0.11903056147364681 0.014729328092219524 1.1412191171158514 -P32316 0.2414838869403105 2.8935358930074644 2.6520520060671537 11.982314553859583 -P07256 0.3054465938153324 0.46527560493242276 0.15982901111709036 1.523263360447621 -P07251 2.894766518281301 6.7356473698430985 3.8408808515617974 2.326836146302476 -P38077 0.5655548996125387 1.3159535831370024 0.7503986835244637 2.326836146302616 -Q12165 0.28021729764507297 0.6520197369797612 0.37180243933468826 2.3268361463024965 -P07255 0.02392126113421865 0.027299400511890733 0.0033781393776720833 1.1412191171158512 -P49367 0.2726539365242995 0.3495680924942362 0.07691415596993673 1.282094426914984 -P09457 0.3756097196518684 0.8739822725885003 0.49837255293663185 2.3268361463024583 -P81449 0.17906247527543434 0.416649039917267 0.23758656464183264 2.3268361463024365 -Q06405 0.18624077972744074 0.4333517781853737 0.24711099845793294 2.3268361463025147 -P00128 0.08857270126065774 0.13491955056623273 0.04634684930557499 1.523263360447621 -P08067 0.14208727531447085 0.21643634047236715 0.0743490651578963 1.523263360447621 -P00127 0.10494329595984693 0.15985627766024568 0.05491298170039875 1.523263360447621 -P19955 0.02211208586550311 0.02427469090675641 0.002162605041253301 1.0978019466099833 -P21147 0.27474046799297513 0.27591719289784133 0.0011767249048661999 1.0042830417865354 -P05374 0.5802740778505086 0.5882767901017606 0.008002712251252042 1.0137912627096772 -P22289 0.04546306313935305 0.06925221833389329 0.023789155194540244 1.523263360447621 -P16451 0.015830710004432248 0.03635455884131801 0.020523848836885763 2.296457886673405 -P07245 0.4622639956098288 1.4142881972243841 0.9520242016145554 3.059481617984598 -P37299 0.0522557653232291 0.07959929268902421 0.027343527365795116 1.523263360447621 -P38698 0.017732073600000002 0.08659455077771722 0.06886247717771721 4.883498271613152 -P08525 0.06674118752734079 0.10166440559316196 0.034923218065821174 1.5232633604476207 -P00044 0.0518380381593484 0.06899111139564522 0.01715307323629682 1.330897422922697 -P00830 2.7063854184190577 6.297315417403474 3.590929998984416 2.326836146302498 -P30902 0.3261518605375327 0.7589019382825541 0.43275007774502144 2.326836146302534 -Q02046 0.06622996754243687 1.1624500859735047 1.0962201184310678 17.551723624636605 -P41939 0.07576568639999999 0.07879530613978455 0.0030296197397845642 1.0399866995699067 -Q12349 0.2326034066468608 0.5412300143390169 0.30862660769215605 2.3268361463025085 -P81450 0.11011123893362372 0.25621081086490266 0.14609957193127893 2.3268361463024623 -P81451 0.12403978381069446 0.28862025255026563 0.16458046873957116 2.3268361463024525 -P18544 0.11453413063235787 0.18136048576115663 0.06682635512879875 1.5834623684646816 -P07143 0.20709532038665973 0.31546071366515993 0.1083653932785002 1.5232633604476207 -Q12189 0.018793604131610277 0.020970191086738973 0.002176586955128696 1.115815302902318 -P33330 0.1744484494884965 1.652937529079184 1.4784890795906873 9.47522052460651 -Q99297 0.03806399419702313 0.07250998295997993 0.0344459887629568 1.9049494013860142 -P46367 1.4511013724419344 2.4298436027656054 0.978742230323671 1.6744823269491018 -P05626 0.44329322791384984 1.0314707061210382 0.5881774782071884 2.3268361463024547 -P21306 0.11101675899064281 0.2583178076647785 0.1473010486741357 2.32683614630248 -Q12233 0.21273135739551322 0.49499101183992333 0.28225965444441015 2.3268361463027234 -P07257 0.2461548782443463 0.3749587070250579 0.12880382878071162 1.523263360447621 +P32473 0.21174583550017084 0.5213025079651714 0.30955667246500057 2.4619256701497245 +P16387 0.24499269123144798 0.6031537955417671 0.3581611043103191 2.4619256701497245 +P16451 0.11990331290206659 0.2951930439695924 0.17528973106752582 2.4619256701497245 +P12695 0.6848408213878672 1.6860271981412127 1.0011863767533455 2.4619256701497245 +P37298 0.021441963419871972 0.030959816942778093 0.009517853522906121 1.4438890849932693 +P47052 0.07346961854894352 0.10608198030143857 0.03261236175249506 1.4438890849932693 +P33421 0.02336812922859078 0.03374098672987441 0.010372857501283632 1.4438890849932693 +P21801 0.03201204978745368 0.046221849276365475 0.014209799488911795 1.4438890849932693 +Q00711 0.07436651928560367 0.10737700548542459 0.033010486199820915 1.443889084993269 +Q06236 0.019729698377157122 0.028487496136986586 0.008757797759829464 1.4438890849932693 +P09624 0.4018980917872603 0.474538824056851 0.07264073226959067 1.1807441581684397 +P07245 0.4622639956098288 1.414288197223803 0.9520242016139743 3.0594816179833413 +P38698 0.03865113268489674 0.1007670271897525 0.06211589450485576 2.6070911818097398 +Q02046 0.07830280654394603 1.1624500859720424 1.0841472794280964 14.845573706475493 +P33330 0.35619373942199145 1.652937529076325 1.2967437896543337 4.640557500417068 diff --git a/results/modelGeneration/relaxedEnzymes_CN4.tsv b/results/modelGeneration/relaxedEnzymes_CN4.tsv index e6b8d25..0cf96f0 100644 --- a/results/modelGeneration/relaxedEnzymes_CN4.tsv +++ b/results/modelGeneration/relaxedEnzymes_CN4.tsv @@ -1,28 +1 @@ protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change -P00856 0.1244097068825561 0.1272455119295709 0.0028358050470147916 1.0227940818933994 -P00854 0.6218134765674198 0.6359871438747137 0.014173667307293858 1.022794081893394 -P61829 1.6580125656162124 1.695805439817143 0.03779287420093058 1.022794081893393 -P07251 3.7571646002951993 3.84280571788129 0.08564111758609094 1.0227940818933943 -P38077 0.7340429132811227 0.75077474755972 0.016731834278597257 1.0227940818933965 -Q12165 0.3636985934629174 0.3719887689868252 0.008290175523907817 1.0227940818933992 -P09457 0.4875099712845447 0.49862231349385616 0.011112342209311454 1.0227940818934051 -P32264 0.02105500328 0.08752024352197224 0.06646524024197224 4.156743286053396 -P81449 0.23240810237971102 0.23770563169804415 0.005297529318333133 1.0227940818934014 -Q06405 0.24172494061412905 0.24723483870616728 0.0055098980920382234 1.0227940818934105 -P05374 0.5802740778505087 0.5859492729997433 0.005675195149234646 1.009780197609821 -P16451 0.0306451097874405 0.2027232103236882 0.1720781005362477 6.615189559763682 -P07275 0.16772672858819115 0.8057981178568774 0.6380713892686862 4.804232006666646 -P38858 0.08949454986540485 0.2164150595995762 0.12692050973417135 2.418192615360971 -P38698 0.026039691049912786 0.035253493823022924 0.009213802773110139 1.3538368698556813 -P00830 3.512661703326766 3.5927296018561874 0.0800678985294212 1.0227940818933945 -P30902 0.4233178106051971 0.43296695144706276 0.009649140841865689 1.0227940818933907 -Q12349 0.30189974902726724 0.30878127663019195 0.0068815276029247086 1.022794081893401 -P81450 0.14291516998119808 0.14617279006955858 0.003257620088360502 1.0227940818933992 -P28239 0.006707538790964384 0.021843091966547216 0.015135553175582833 3.2564987914750025 -P12695 0.47461200059426184 1.1578756792637974 0.6832636786695356 2.4396257949946922 -P81451 0.16099325517917626 0.1646629486220177 0.003669693442841432 1.022794081893414 -Q12189 0.07555817722670258 0.07580034815639593 0.00024217092969334997 1.0032050922690572 -P33330 0.3453844651148362 0.3614952555773211 0.01611079046248487 1.0466459615001162 -P05626 0.5753574987655143 0.5884722447103565 0.013114745944842188 1.0227940818933987 -P21306 0.14409045920801802 0.1473748689352622 0.0032844097272441697 1.022794081893393 -Q12233 0.2761074927219503 0.28240110952284186 0.006293616800891577 1.0227940818948709 diff --git a/results/modelGeneration/relaxedEnzymes_CN75.tsv b/results/modelGeneration/relaxedEnzymes_CN75.tsv index b2990fe..30c4328 100644 --- a/results/modelGeneration/relaxedEnzymes_CN75.tsv +++ b/results/modelGeneration/relaxedEnzymes_CN75.tsv @@ -1,55 +1,20 @@ protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change -P00401 0.15027233036205045 0.2835792387754299 0.13330690841337944 1.8871021570784436 -P00856 0.06124939214474812 0.2751175256100435 0.21386813346529537 4.491759280808368 -P00854 0.30613123703538914 1.3750678250990473 1.068936588063658 4.491759280808341 -P00163 0.17725528802146923 0.49793822503439455 0.32068293701292533 2.809158646787926 -P61829 0.8162728163021216 3.6665009982966805 2.850228181994559 4.491759280808419 -P00410 0.07300979049377011 0.13777693312863884 0.06476714263486873 1.8871021570784439 -P00420 0.07759223017435715 0.1464244649345565 0.06883223476019934 1.8871021570784436 -P32316 0.14602662293185484 3.0303297919070062 2.8843031689751513 20.751899421252435 -P07256 0.20393940367285954 0.5728981392483867 0.36895873557552716 2.8091586467879264 -P07251 1.8497274346372068 8.308530371497815 6.458802936860608 4.491759280808523 -P38077 0.3613840380563813 1.6232501068757477 1.2618660688193664 4.491759280808347 -P20049 0.011258626671619783 0.029551588300729063 0.018292961629109282 2.624795116017242 -Q12165 0.1790561068882825 0.8042769299008827 0.6252208230126002 4.491759280808505 -P07255 0.017795609311727564 0.03358213271868632 0.015786523406958755 1.8871021570784434 -P48445 0.3118941754425341 0.32782413632961954 0.015929960887085426 1.0510748905922436 -P49367 0.2726539365242995 0.37736103598279236 0.10470709945849288 1.3840292965994319 -P09457 0.24001092964449416 1.0780713207261305 0.8380603910816364 4.491759280808491 -P81449 0.11441916677538098 0.5139433542656875 0.3995241874903065 4.491759280808451 -Q06405 0.11900603296828778 0.534546453057508 0.41554042008922026 4.491759280808492 -P00128 0.059137879559114426 0.16612768571618924 0.10698980615707482 2.8091586467879264 -P08067 0.09486828396146299 0.26650006019627615 0.17163177623481315 2.809158646787927 -P00127 0.07006813508765106 0.19683250754577947 0.1267643724581284 2.8091586467879264 -P19955 0.01627797567671049 0.026311597158465688 0.010033621481755198 1.6163924606491873 -P21147 0.27474046799297513 0.2799103561676136 0.005169888174638482 1.0188173522903465 -P05374 0.5802740778505084 0.58827679010176 0.008002712251251598 1.0137912627096763 -P22289 0.030354602649086126 0.08527089450149197 0.054916291852405846 2.809158646787926 -P16451 0.012415452765071642 0.042035396255539016 0.029619943490467374 3.3857320430389035 -P07245 0.4711009058569384 1.9702619828663277 1.4991610770093893 4.182250465603323 -P37299 0.034889927844247874 0.09801134248947574 0.06312141464522786 2.809158646787926 -P38698 0.018554106585468057 0.11711174148354647 0.09855763489807842 6.311904102958571 -P20967 0.20881967827818368 0.21991874501300385 0.011099066734820168 1.0531514406416924 -P08525 0.04456149867224722 0.12518031930897197 0.08061882063672475 2.809158646787926 -P00044 0.03860557158659841 0.1290438586620156 0.09043828707541718 3.342622667107772 -P05375 0.008413979548481082 0.008530018950868027 0.00011603940238694502 1.0137912627096761 -P00830 1.7293537580793068 7.767840792653756 6.038487034574449 4.491759280808484 -P30902 0.2084078423887717 0.9361178602430369 0.7277100178542653 4.491759280808483 -P33421 0.023408097243561434 0.03581081125091745 0.012402714007356017 1.5298471669143239 -Q02046 0.05988304705825437 1.5924764694335076 1.5325934223752533 26.593110198356186 -P21801 0.03206680205592286 0.049057306277256005 0.016990504221333143 1.5298471669143239 -P41939 0.025097063639941897 0.0822147710072732 0.05711770736733131 3.2758721174228786 -P27472 0.04485511016531227 0.0493137773217936 0.004458667156481334 1.0994015428799313 -Q12349 0.14863129718670356 0.6676160085569725 0.5189847113702689 4.491759280808435 -P81450 0.07036000251873406 0.3160401943112282 0.24568019179249415 4.49175928080843 -Q00955 1.045025648284381 1.0747581420652574 0.0297324937808765 1.028451448851699 -P81451 0.07926020618662247 0.3560177667375588 0.27675756055093637 4.491759280808526 -P18544 0.11453413063235787 0.18555793101899462 0.07102380038663675 1.6201103548305216 -P07143 0.13827260476386144 0.38842968328629074 0.2501570785224293 2.809158646787926 -Q12189 0.01879360413161142 0.026838128429107724 0.008044524297496303 1.4280458522570008 -P33330 0.15976919798682934 2.16729019381329 2.0075209958264604 13.565131584324229 -P46367 1.1746796399999733 3.1178258801981817 1.9431462401982085 2.654192491323211 -P05626 0.2832600280826759 1.272335860022401 0.9890758319397251 4.491759280808377 -P21306 0.07093862096050044 0.3186392090670771 0.24770058810657666 4.4917592808084 -Q12233 0.13593325247377347 0.6105794483695244 0.4746461958957509 4.49175928080826 -P07257 0.16435173970434835 0.4616901107051087 0.2973383710007603 2.809158646787926 +P32473 0.1732853446936278 0.5842335043294654 0.41094815963583764 3.3715113379172528 +P16387 0.20049340213553685 0.6759657784775657 0.4754723763420288 3.371511337917253 +P16451 0.09812465429161062 0.330828384473376 0.23270373018176538 3.3715113379172523 +P12695 0.5604496424411047 1.8895623238218549 1.3291126813807501 3.3715113379172528 +P19262 0.09204119349782444 0.09918671238115896 0.00714551888333452 1.0776339225056162 +P20967 0.20881967827818368 0.22503116899927988 0.016211490721096206 1.0776339225056162 +P19955 0.02498367864590666 0.026923259617808195 0.0019395809719015347 1.0776339225056162 +P37298 0.012798047684081222 0.03361023711505835 0.02081218943097713 2.626200334982675 +P47052 0.043851752897275095 0.11516348814840133 0.07131173525112623 2.626200334982675 +P33421 0.013947716741187437 0.036629498377949904 0.022681781636762467 2.6262003349826744 +P21801 0.019107006742923573 0.05017882750878211 0.031071820765858536 2.626200334982675 +Q00711 0.04438708532793423 0.11656937835712543 0.0721822930291912 2.6262003349826744 +Q06236 0.01177604940736833 0.030926264898403236 0.019150215491034905 2.626200334982675 +P09624 0.3072933945060969 0.6592887237000167 0.3519953291939198 2.14546988476492 +P07245 0.4711009058569384 1.970425541332419 1.4993246354754806 4.18259764911339 +P38698 0.019802643436024628 0.12862667749013468 0.10882403405411005 6.495429658453539 +Q02046 0.07864374572756741 1.5926029762169795 1.513959230489412 20.25085353556241 +P41939 0.025097063639941897 0.04064097298936423 0.01554390934942233 1.6193517127112929 +P33330 0.3566015352790652 2.1674415080199982 1.810839972740933 6.078048728320327 diff --git a/results/modelGeneration/relaxedEnzymes_hGR.tsv b/results/modelGeneration/relaxedEnzymes_hGR.tsv index 5353202..291b959 100644 --- a/results/modelGeneration/relaxedEnzymes_hGR.tsv +++ b/results/modelGeneration/relaxedEnzymes_hGR.tsv @@ -1,49 +1,9 @@ protein measured_mg_gDW relaxed_mg_gDW added_mg_gDW fold_change -P00401 0.27961048753338874 0.3799707799915213 0.10036029245813255 1.358928927678896 -P00856 0.2872915858737157 0.37317999216072306 0.08588840628700734 1.2989590037097751 -P00854 1.435915124929442 1.8651948800901545 0.4292797551607126 1.2989590037097816 -P00163 0.4801925257421121 0.6683311700802995 0.18813864433818744 1.3917983605584638 -P61829 3.8287451301857818 4.9733829597647725 1.1446378295789907 1.298959003709774 -P00410 0.1358487158979252 0.18460874982172504 0.04876003392379985 1.358928927678915 -P00420 0.14437522367280708 0.19619566788908782 0.05182044421628074 1.3589289276788914 -P32316 0.8125186921989169 4.298455689527719 3.4859369973288024 5.290285295338648 -P07256 0.5524809919134764 0.7689421387848929 0.2164611468714165 1.3917983605584683 -P07251 8.676186155043027 11.270010123955164 2.5938239689121367 1.298959003709767 -P38077 1.6950795716846534 2.20183887164428 0.5067592999596264 1.2989590037097694 -Q12165 0.839866504907362 1.0909521584636734 0.2510856535563114 1.2989590037097698 -P07255 0.0331121436901765 0.04499704991804079 0.01188490622786429 1.3589289276788874 -P07284 0.27566745708392604 0.3016596848897915 0.025992227805865464 1.094288343211844 -P49367 0.7906964159204685 1.1805435772535076 0.3898471613330391 1.4930427828981732 -P09457 1.1257764067541924 1.4623373997174058 0.3365609929632134 1.2989590037097836 -P81449 0.5366855527245878 0.6971325308725564 0.1604469781479686 1.2989590037097674 -Q06405 0.5582003468572905 0.7250793664242698 0.16687901956697937 1.2989590037099057 -P00128 0.1602071682571417 0.22297607413000647 0.06276890587286477 1.3917983605584805 -P08067 0.2570024364111305 0.35769556965654664 0.10069313324541612 1.3917983605584807 -Q01217 0.45018264581677947 0.6186826830505349 0.1685000372337554 1.3742926094541936 -P23337 0.02901643752090748 0.16282904336395587 0.13381260584304838 5.611613873916506 -P00127 0.18981772074242884 0.26418799253426173 0.07437027179183289 1.39179836055849 -P05374 1.6827948257664744 1.7061095325235494 0.02331470675707492 1.013854753057287 -P22289 0.08223198008172393 0.11445033506322887 0.03221835498150494 1.3917983605585764 -P16451 0.015413923384667414 0.09951677526917795 0.08410285188451053 6.456291028938783 -P37299 0.0945183794599109 0.13155052557494992 0.03703214611503902 1.3917983605584971 -P38698 0.016928058663478077 0.16361767872931243 0.14668962006583436 9.665472100608563 -P08525 0.12071909863522859 0.16801664356861112 0.047297544933382535 1.391798360558501 -P00044 0.05948236179883932 0.16847634416118706 0.10899398236234775 2.832374826187123 -P05375 0.024400540690595128 0.024738604156327608 0.0003380634657324799 1.013854753057287 -P00830 8.111570846633313 10.536597985462723 2.4250271388294102 1.2989590037096097 -P30902 0.9775414490139027 1.2697862666959676 0.2922448176820649 1.2989590037096306 -Q02046 0.07396682372390692 0.23437891316230705 0.16041208943840013 3.168703228857901 -P20485 0.05452403402063208 0.07273775721295686 0.018213723192324782 1.3340494429563419 -Q12349 0.69715828327444 0.9055800290701984 0.20842174579575845 1.2989590037097962 -P81450 0.33002509899062105 0.42868907378408033 0.09866397479345929 1.2989590037097851 -P12695 0.2950317924047663 0.5684008929167875 0.27336910051202123 1.9265750591955693 -P81451 0.371771694945478 0.48291619047387274 0.11114449552839473 1.2989590037097756 -P18544 0.33214897883383776 0.5275408553940657 0.19539187656022794 1.5882657753344336 -P07143 0.3745866882936513 0.5213491386541277 0.14676245036047636 1.3917983605584623 -Q12189 0.05450145198167168 0.08586825962325949 0.03136680764158781 1.5755224219005426 -P33330 0.2053005399367211 1.0417046197023159 0.8364040797655947 5.074047150696224 -P46367 1.9633835444474308 3.282009928286654 1.3186263838392234 1.671609165498193 -P05626 1.3286372294142705 1.7258452918116571 0.3972080623973866 1.2989590037097603 -P21306 0.3327391211862686 0.43221447735138363 0.09947535616511505 1.2989590037097813 -Q12233 0.6375978325445247 0.8282134453295606 0.19061561278503591 1.2989590037097951 -P07257 0.44523623458377254 0.6196790613549196 0.17444282677114703 1.3917983605584667 +P32473 0.5108538039419748 0.702217370649955 0.19136356670798027 1.3745955598868678 +P16387 0.5910645088151729 0.8124746494240492 0.22141014060887632 1.374595559886868 +P16451 0.2892763551008122 0.39763799330183336 0.10836163820102118 1.374595559886868 +P12695 1.6522333857208555 2.271152675908735 0.6189192901878795 1.374595559886868 +P09624 0.6010326641431301 0.6377941773486022 0.03676151320547216 1.0611639190323903 +Q02046 0.23401204348791213 0.2343789131624736 0.0003668696745614819 1.0015677384338573 +Q12189 0.05465727123367742 0.06829139970481886 0.01363412847114144 1.2494476610962 +P33330 1.0412658084995001 1.0417046197026731 0.00043881120317301736 1.0004214209278661 diff --git a/results/modelGeneration/respiratoryKcats.tsv b/results/modelGeneration/respiratoryKcats.tsv new file mode 100644 index 0000000..c348164 --- /dev/null +++ b/results/modelGeneration/respiratoryKcats.tsv @@ -0,0 +1,4 @@ +complex reaction condition kcat_per_s ecmodel_kcat_per_s +ATP synthase r_0226 CN75 1607.695903 84.649052 +complex III r_0439 CN75 1452.134199 290.494288 +complex IV r_0438 CN75 3242.055529 1376.34631 diff --git a/results/modelGeneration/respiratoryTurnover.tsv b/results/modelGeneration/respiratoryTurnover.tsv new file mode 100644 index 0000000..f53e547 --- /dev/null +++ b/results/modelGeneration/respiratoryTurnover.tsv @@ -0,0 +1,16 @@ +condition complex reaction flux_mmol_gDW_h abundance_nmol_gDW apparent_turnover_per_s ecmodel_kcat_per_s relative_to_highest +CN4 complex III r_0439 5.630143 4.996409 313.010557 290.494288 0.215552 +CN4 complex IV r_0438 11.260725 4.549763 687.503779 1376.34631 0.212058 +CN4 ATP synthase r_0226 7.411385 6.185303 332.840321 84.649052 0.207029 +CN22 complex III r_0439 8.629349 4.755014 504.108161 290.494288 0.34715 +CN22 complex IV r_0438 17.260503 3.94075 1216.667914 1376.34631 0.375277 +CN22 ATP synthase r_0226 11.165828 5.608082 553.062307 84.649052 0.344009 +CN38 complex III r_0439 10.032796 4.400961 633.24522 290.494288 0.436079 +CN38 complex IV r_0438 20.126902 3.101699 1802.498061 1376.34631 0.555974 +CN38 ATP synthase r_0226 12.982189 3.836353 939.997881 84.649052 0.584686 +CN75 complex III r_0439 13.557278 2.593363 1452.134199 290.494288 1.0 +CN75 complex IV r_0438 27.122409 2.323835 3242.055529 1376.34631 1.0 +CN75 ATP synthase r_0226 17.178438 2.968091 1607.695903 84.649052 1.0 +hGR complex III r_0439 15.773079 4.583696 955.868538 290.494288 0.658251 +hGR complex IV r_0438 31.547274 2.994478 2926.430457 1376.34631 0.902647 +hGR ATP synthase r_0226 20.091471 5.304047 1052.208671 84.649052 0.654482 diff --git a/results/modelGeneration/ribosomeSummary.tsv b/results/modelGeneration/ribosomeSummary.tsv index 73f5a02..776fef1 100644 --- a/results/modelGeneration/ribosomeSummary.tsv +++ b/results/modelGeneration/ribosomeSummary.tsv @@ -1,6 +1,6 @@ condition subunits translation_kcat aa_per_protein subunits_raised growth_before growth_after pool_before pool_after ribosome_mg_gDW ribosome_fraction -CN4 48 2.5054 4.191 0 0.1 0.1 41.8 53.4 11.6 0.2171 -CN22 48 2.5054 4.191 0 0.1 0.1 74.3 85.9 11.6 0.135 -CN38 48 2.5054 4.191 3 0.1 0.1 79.4 91.0 11.6 0.1274 -CN75 48 2.5054 4.191 5 0.1 0.1 101.5 113.1 11.6 0.1026 -hGR 48 2.5054 4.191 12 0.29 0.29 133.1 166.7 33.6 0.2017 +CN4 48 2.5054 4.191 0 0.1 0.1 27.1 38.7 11.6 0.2994 +CN22 48 2.5054 4.191 0 0.1 0.1 53.1 64.7 11.6 0.1792 +CN38 48 2.5054 4.191 3 0.1 0.1 49.7 61.3 11.6 0.1892 +CN75 48 2.5054 4.191 5 0.1 0.1 69.3 80.9 11.6 0.1434 +hGR 48 2.5054 4.191 12 0.29 0.29 86.4 120.1 33.6 0.2802 diff --git a/results/modelGeneration/summary.tsv b/results/modelGeneration/summary.tsv index dadaca3..4898e7a 100644 --- a/results/modelGeneration/summary.tsv +++ b/results/modelGeneration/summary.tsv @@ -1,2 +1,6 @@ -condition f Ptot_measured Ptot_rescaled GAM pool_mg_gDW proteins_kept model_enzymes_measured raised_to_minimum flexibilized pool_increases rates_relaxed rates_added_mg NGAM NGAM_error growth glucose CO2 O2 pool_used_mg_gDW -CN22 0.5782 0.55 0.589 55.3 340.5 2116 613 28 8 0 23 6.3 0.0 inf 0.1 1.5961 4.3953 3.8505 74.3 +condition f Ptot_measured Ptot_rescaled GAM pool_mg_gDW proteins_kept model_enzymes_measured raised_to_minimum flexibilized pool_increases rates_relaxed rates_added_mg NGAM NGAM_error growth glucose CO2 O2 pool_used_mg_gDW ethanol +CN4 0.5846 0.5 0.5725 55.3 334.7 2107 627 9 12 0 0 0.0 0.0 inf 0.1 1.2047 3.1013 2.7301 27.1 0.0 +CN22 0.5782 0.55 0.589 55.3 340.5 2116 633 11 5 0 3 0.3 0.0 0.1386 0.1 1.5961 4.3953 3.8505 53.1 0.0 +CN38 0.569 0.33 0.3524 55.3 200.5 2190 640 18 8 0 15 5.42 0.3 0.1205 0.1 2.1747 5.799 4.9542 49.7 0.7467 +CN75 0.57 0.27 0.2958 55.3 168.6 2147 625 18 9 0 19 8.01 0.0 0.1386 0.1 3.4855 8.5106 6.1282 69.3 2.1 +hGR 0.5437 0.41 0.4448 55.3 241.9 2004 599 24 16 0 8 1.19 0.0 0.1137 0.29 5.8488 11.9159 7.5735 86.4 3.386 diff --git a/results/modelSimulation/allFluxes_CN22.tsv b/results/modelSimulation/allFluxes_CN22.tsv index bf32e0c..2f50cc8 100644 --- a/results/modelSimulation/allFluxes_CN22.tsv +++ b/results/modelSimulation/allFluxes_CN22.tsv @@ -1,9 +1,9 @@ rxnID rxnName equation flux -r_0001_EXP_1 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 3.143317927979973 prot_P32891 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.03340847909800042 +r_0001_EXP_1 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 3.143317927979973 prot_P32891 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 r_0001_EXP_2 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 3.143317927979973 prot_P32891 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 -r_0001_EXP_3 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 2.658626997881764 prot_P39976 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.037079922310816936 +r_0001_EXP_3 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 2.658626997881764 prot_P39976 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 r_0001_EXP_4 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 2.658626997881764 prot_P39976 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 -r_0002_EXP_1 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 2.853264009243212 prot_P46681 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.013970347150235247 +r_0002_EXP_1 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 2.853264009243212 prot_P46681 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 r_0002_EXP_2 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 2.853264009243212 prot_P46681 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 r_0003 (R,R)-butanediol dehydrogenase 0.11954621771429885 prot_P39714 + (R,R)-2,3-butanediol + NAD --> (R)-acetoin + H+ + NADH 0.0 r_0003_REV (R,R)-butanediol dehydrogenase (reversible) 0.0770037037037037 prot_P39714 + (R)-acetoin + H+ + NADH --> (R,R)-2,3-butanediol + NAD 0.0 @@ -17,10 +17,10 @@ r_0006_EXP_2 1,6-beta-glucan synthase 1.4417126800627231 prot_P32486 + UDP-D-glu r_0007 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase 0.25657118055555556 prot_P40545 + 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide --> 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide 0.008356708763266002 r_0012 1-pyrroline-5-carboxylate dehydrogenase 11.932407407407407 prot_P07275 + 1-pyrroline-5-carboxylate + 2.0 H2O + NAD --> H+ + L-glutamate + NADH 0.06895229872539321 r_0013 2,3-diketo-5-methylthio-1-phosphopentane degradation reaction 0.013992777777777778 prot_P32626 + 0.011599444444444445 prot_Q03677 + 5-(methylsulfanyl)-2,3-dioxopentyl phosphate + H2O + oxygen --> 4-methylthio-2-oxobutanoate + formate + 2.0 H+ + phosphate 0.0024387474967028553 -r_0014 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase 188.09203142536475 prot_Q12362 + 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + H+ + H2O --> 5-amino-6-(5-phosphoribitylamino)uracil + ammonium 9.999999710998968e-05 -r_0015 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH) 0.5311659867712155 prot_P33312 + 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + H+ + NADPH --> 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + NADP(+) 9.999999710998968e-05 +r_0014 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase 188.09203142536475 prot_Q12362 + 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + H+ + H2O --> 5-amino-6-(5-phosphoribitylamino)uracil + ammonium 9.99999971099883e-05 +r_0015 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH) 0.5311659867712155 prot_P33312 + 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + H+ + NADPH --> 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + NADP(+) 9.99999971099883e-05 r_0016_EXP_1 2-aceto-2-hydroxybutanoate synthase 0.08099546044098574 prot_P07342 + 0.03673476005188067 prot_P25605 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.0 -r_0016_EXP_2 2-aceto-2-hydroxybutanoate synthase 0.04049773022049287 prot_P07342 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.03686112717615209 +r_0016_EXP_2 2-aceto-2-hydroxybutanoate synthase 0.04049773022049287 prot_P07342 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.0265490320174191 r_0017 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 63.477512816721614 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + ATP --> (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + AMP + H+ 0.0 r_0018_EXP_1 2-aminoadipate transaminase 0.7210471896303212 prot_P10356 + 2-oxoadipic acid + L-glutamate --> 2-oxoglutarate + L-2-aminoadipate 0.0 r_0018_EXP_2 2-aminoadipate transaminase 1.219140625 prot_P53090 + 2-oxoadipic acid + L-glutamate --> 2-oxoglutarate + L-2-aminoadipate 0.0 @@ -28,9 +28,9 @@ r_0018_EXP_3 2-aminoadipate transaminase 0.009033549783549784 prot_P47039 + 2-ox r_0018_REV_EXP_1 2-aminoadipate transaminase (reversible) 0.7210471896303212 prot_P10356 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 r_0018_REV_EXP_2 2-aminoadipate transaminase (reversible) 0.8480978260869565 prot_P53090 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 r_0018_REV_EXP_3 2-aminoadipate transaminase (reversible) 1.8137766188613647 prot_P47039 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 -r_0019 2-dehydropantoate 2-reductase 0.4757888888888889 prot_P38787 + 2-dehydropantoate + H+ + NADPH --> (R)-pantoate + NADP(+) 1.900000061143747e-05 +r_0019 2-dehydropantoate 2-reductase 0.4757888888888889 prot_P38787 + 2-dehydropantoate + H+ + NADPH --> (R)-pantoate + NADP(+) 1.9000000611588824e-05 r_0020_EXP_1 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09351092896174863 prot_P14843 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 -r_0020_EXP_2 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.04594319592130103 +r_0020_EXP_2 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0334524833254565 r_0021 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase 0.2834173315594083 prot_O13525 + 0.266570923780901 prot_P27680 + 0.191209663200305 prot_P41735 + 0.2544937516539746 prot_P49017 + 0.39274288726487816 prot_P53318 + 0.21981040253855474 prot_Q05779 + 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine --> 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + S-adenosyl-L-homocysteine 0.0 r_0022 2-hexaprenyl-6-methoxyphenol monooxygenase 0.5305538973582232 prot_O13525 + 0.49901762096258073 prot_P27680 + 0.3579422312153493 prot_P41735 + 0.47640929737929355 prot_P49017 + 0.7352100464414428 prot_P53318 + 0.4114824774654426 prot_Q05779 + 2-hexaprenyl-6-methoxyphenol + oxygen --> 2-hexaprenyl-6-methoxy-1,4-benzoquinone + H2O 0.0 r_0023 2-isopropylmalate hydratase 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> 2-isopropylmalate 0.0 @@ -44,28 +44,28 @@ r_0026_EXP_3 2-keto-4-methylthiobutyrate transamination 1.219140625 prot_P53090 r_0026_EXP_4 2-keto-4-methylthiobutyrate transamination 1.5784250269687163 prot_P38840 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 r_0027 2-methylcitrate dehydratase 8.195345706873871 prot_P49367 + homocitrate --> but-1-ene-1,2,4-tricarboxylic acid + H2O 0.032939964005654 r_0027_REV 2-methylcitrate dehydratase (reversible) 8.350111111111111 prot_P49367 + but-1-ene-1,2,4-tricarboxylic acid + H2O --> homocitrate 0.0 -r_0028 2-methylcitrate synthase 0.10578556263269638 prot_P43635 + H2O + oxaloacetate + propionyl-CoA --> 2-methylcitrate + coenzyme A + H+ 0.0 +r_0028 2-methylcitrate synthase 0.10578556263269638 prot_P43635 + H2O + oxaloacetate + propionyl-CoA --> 2-methylcitrate + coenzyme A + H+ 1.9999991326180577e-05 r_0029 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.0362523293945085 r_0030 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.0 -r_0032 3',5'-bisphosphate nucleotidase 0.9886111111111111 prot_P32179 + adenosine 3',5'-bismonophosphate + H2O --> AMP + phosphate 0.011924916613574123 +r_0032 3',5'-bisphosphate nucleotidase 0.9886111111111111 prot_P32179 + adenosine 3',5'-bismonophosphate + H2O --> AMP + phosphate 0.011924916613574275 r_0033_EXP_1 3',5'-cyclic-nucleotide phosphodiesterase 0.5557671957671958 prot_P22434 + 3',5'-cyclic AMP + H2O --> AMP + H+ 0.0 r_0033_EXP_2 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic AMP + H2O --> AMP + H+ 0.0 r_0034 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic dAMP + H2O --> dAMP + H+ 0.0 r_0035 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic IMP + H2O --> H+ + IMP 0.0 r_0036 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic GMP + H2O --> GMP + H+ 0.0 r_0037 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic CMP + H2O --> CMP + H+ 0.0 -r_0038 3,4-dihydroxy-2-butanone-4-phosphate synthase 2.8494949494949493 prot_Q99258 + D-ribulose 5-phosphate --> 2-hydroxy-3-oxobutyl phosphate + formate + H+ 0.00019999999421997937 -r_0039 3-dehydroquinate dehydratase 0.1565905017921147 prot_P08566 + 3-dehydroquinate --> 3-dehydroshikimate + H2O 0.04594319592130103 -r_0040 3-dehydroquinate synthase 0.1565905017921147 prot_P08566 + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 3-dehydroquinate + phosphate 0.04594319592130103 +r_0038 3,4-dihydroxy-2-butanone-4-phosphate synthase 2.8494949494949493 prot_Q99258 + D-ribulose 5-phosphate --> 2-hydroxy-3-oxobutyl phosphate + formate + H+ 0.0001999999942199766 +r_0039 3-dehydroquinate dehydratase 0.1565905017921147 prot_P08566 + 3-dehydroquinate --> 3-dehydroshikimate + H2O 0.0334524833254565 +r_0040 3-dehydroquinate synthase 0.1565905017921147 prot_P08566 + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 3-dehydroquinate + phosphate 0.0334524833254565 r_0041 3-dehydrosphinganine reductase 9.338785046728972 prot_P38342 + 3-ketosphinganine + H+ + NADPH --> NADP(+) + sphinganine 0.0 r_0042_EXP_1 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 r_0042_EXP_2 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09351092896174863 prot_P14843 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 r_0043_EXP_1 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase 0.2467406921478821 prot_Q12184 + 3-hexaprenyl-4-hydroxybenzoic acid + 0.5 oxygen --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 r_0043_EXP_2 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase 0.30872310057092667 prot_P48360 + 3-hexaprenyl-4-hydroxybenzoic acid + 0.5 oxygen --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 r_0044 3-hexaprenyl-4-hydroxy-5-methoxybenzoate decarboxylase 1.6143115942028985 prot_P33751 + 3.391545893719807 prot_Q03034 + 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid + H+ --> 2-hexaprenyl-6-methoxyphenol + carbon dioxide 0.0 -r_0045 3-hydroxy-L-kynurenine hydrolase 4.0501587301587305 prot_Q05979 + 3-hydroxy-L-kynurenine + H2O --> 3-hydroxyanthranilate + H+ + L-alanine 0.0006069999974000248 -r_0057 3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxytetradecanoyl-CoA + NAD --> 3-oxotetradecanoyl-CoA + H+ + NADH 7.302847455517871e-06 -r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.22483333333333333 prot_P47096 + 3-hydroxyanthranilate + oxygen --> 2-amino-3-carboxymuconate-6-semialdehyde 0.0006069999974000248 +r_0045 3-hydroxy-L-kynurenine hydrolase 4.0501587301587305 prot_Q05979 + 3-hydroxy-L-kynurenine + H2O --> 3-hydroxyanthranilate + H+ + L-alanine 0.0006069999973989104 +r_0057 3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxytetradecanoyl-CoA + NAD --> 3-oxotetradecanoyl-CoA + H+ + NADH 0.0 +r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.22483333333333333 prot_P47096 + 3-hydroxyanthranilate + oxygen --> 2-amino-3-carboxymuconate-6-semialdehyde 0.0006069999973989104 r_0059 3-isopropylmalate 3-methyltransferase 195.1806339044363 prot_P32643 + (2R,3S)-3-isopropylmalate + S-adenosyl-L-methionine --> 3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoate + S-adenosyl-L-homocysteine 0.0 r_0060 3-isopropylmalate dehydratase 0.6097968324816225 prot_P07264 + (2R,3S)-3-isopropylmalate --> 2-isopropylmaleic acid + H2O 0.0 r_0060_REV 3-isopropylmalate dehydratase (reversible) 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> (2R,3S)-3-isopropylmalate 0.0362523293945085 @@ -73,12 +73,12 @@ r_0061 3-isopropylmalate dehydrogenase 0.06638207225630538 prot_P04173 + (2R,3S) r_0062_EXP_1 3-methyl-2-oxobutanoate decarboxylase 0.27589605734767025 prot_P26263 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 r_0062_EXP_2 3-methyl-2-oxobutanoate decarboxylase 0.11780651340996169 prot_P06169 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 r_0062_EXP_3 3-methyl-2-oxobutanoate decarboxylase 0.27738351254480287 prot_P16467 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 -r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.226834113807293 prot_P38122 + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O --> 2-dehydropantoate + THF 1.900000061143747e-05 +r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.226834113807293 prot_P38122 + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O --> 2-dehydropantoate + THF 1.9000000611588824e-05 r_0064_EXP_1 3-methyl-2-oxopentanoate decarboxylase 0.13096934865900384 prot_Q07471 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_2 3-methyl-2-oxopentanoate decarboxylase 0.27589605734767025 prot_P26263 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 -r_0064_EXP_3 3-methyl-2-oxopentanoate decarboxylase 0.11780651340996169 prot_P06169 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.010312095158732992 +r_0064_EXP_3 3-methyl-2-oxopentanoate decarboxylase 0.11780651340996169 prot_P06169 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_4 3-methyl-2-oxopentanoate decarboxylase 0.27738351254480287 prot_P16467 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 -r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 1.4447337962962963 prot_P08566 + 3-phosphoshikimic acid + phosphoenolpyruvate --> 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid + phosphate 0.04594319592130103 +r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 1.4447337962962963 prot_P08566 + 3-phosphoshikimic acid + phosphoenolpyruvate --> 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid + phosphate 0.0334524833254565 r_0066 4-amino-4-deoxychorismate synthase 1446.797385620915 prot_P37254 + chorismate + L-glutamine --> 4-amino-4-deoxychorismate + L-glutamate 6.3400002545677125e-06 r_0067 4-aminobenzoate synthase 6.233918128654971 prot_Q03266 + 4-amino-4-deoxychorismate --> 4-aminobenzoate + H+ + pyruvate 6.3400002545677125e-06 r_0068 4-aminobutyrate transaminase 43.25653594771242 prot_P17649 + 2-oxoglutarate + gamma-aminobutyrate --> L-glutamate + succinic semialdehyde 0.002263983507354179 @@ -94,8 +94,8 @@ r_0076_EXP_2 5'-nucleotidase (CMP) 51.769157967243395 prot_P53078 + CMP + H2O -- r_0077 5'-nucleotidase (IMP) 1.056172839506173 prot_Q99312 + H2O + IMP --> inosine + phosphate 0.0 r_0078_EXP_1 5'-nucleotidase (UMP) 0.029597457627118642 prot_P40025 + H2O + UMP --> phosphate + uridine 0.0 r_0078_EXP_2 5'-nucleotidase (UMP) 201.12835425109543 prot_P53078 + H2O + UMP --> phosphate + uridine 0.0 -r_0079 5'-phosphoribosylformyl glycinamidine synthetase 112.56379587281619 prot_P38972 + 5'-phosphoribosyl-N-formylglycineamide + ATP + H2O + L-glutamine --> 5'-phosphoribosyl-N-formylglycineamidine + ADP + H+ + L-glutamate + phosphate 0.01024042638525706 -r_0080_EXP_1 5,10-methylenetetrahydrofolate reductase (NADPH) 0.12837152777777777 prot_P46151 + 0.11902777777777777 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.022080578792112577 +r_0079 5'-phosphoribosylformyl glycinamidine synthetase 112.56379587281619 prot_P38972 + 5'-phosphoribosyl-N-formylglycineamide + ATP + H2O + L-glutamine --> 5'-phosphoribosyl-N-formylglycineamidine + ADP + H+ + L-glutamate + phosphate 0.01024042638525704 +r_0080_EXP_1 5,10-methylenetetrahydrofolate reductase (NADPH) 0.12837152777777777 prot_P46151 + 0.11902777777777777 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.022080578792112567 r_0080_EXP_2 5,10-methylenetetrahydrofolate reductase (NADPH) 0.3705144833549503 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.0 r_0081 5-aminolevulinate synthase 0.08588252314814815 prot_P09950 + H+ + L-glycine + succinyl-CoA --> 5-aminolevulinate + carbon dioxide + coenzyme A 0.0 r_0082 5-diphosphoinositol-1,2,3,4,6-pentakisphosphate diphosphohydrolase 2396.8888888888887 prot_Q99321 + 5-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 @@ -112,7 +112,7 @@ r_0089_REV 5PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 (reversible) 0.94850146198 r_0090_EXP_1 6-phosphofructo-2-kinase 0.4896069182389937 prot_P40433 + ATP + D-fructose 6-phosphate --> ADP + beta-D-fructose 2,6-bisphosphate + H+ 0.0 r_0090_EXP_2 6-phosphofructo-2-kinase 0.23751572327044027 prot_Q12471 + ATP + D-fructose 6-phosphate --> ADP + beta-D-fructose 2,6-bisphosphate + H+ 0.0 r_0091_EXP_1 6-phosphogluconolactonase 0.8951362104267674 prot_P53315 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.0 -r_0091_EXP_2 6-phosphogluconolactonase 0.87424298616765 prot_P38858 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.019382600019956696 +r_0091_EXP_2 6-phosphogluconolactonase 0.87424298616765 prot_P38858 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.03187331261580455 r_0092_EXP_1 6PP-IP5 depyrophosphorylation to IP6 0.9485014619883041 prot_Q06685 + 6-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0092_EXP_2 6PP-IP5 depyrophosphorylation to IP6 2396.8888888888887 prot_Q99321 + 6-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0093 6PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 1106.9444444444443 prot_Q12494 + 6-diphospho-1D-myo-inositol pentakisphosphate + ATP + H+ --> 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + ADP 0.0 @@ -120,9 +120,9 @@ r_0094 8-amino-7-oxononanoate synthase 1.1329040404040405 prot_standard + H+ + L r_0095_EXP_1 acetaldehyde condensation 0.27589605734767025 prot_P26263 + 2.0 acetaldehyde --> (R)-acetoin 0.0 r_0095_EXP_2 acetaldehyde condensation 0.11780651340996169 prot_P06169 + 2.0 acetaldehyde --> (R)-acetoin 0.0 r_0095_EXP_3 acetaldehyde condensation 0.27738351254480287 prot_P16467 + 2.0 acetaldehyde --> (R)-acetoin 0.0 -r_0096 acetohydroxy acid isomeroreductase 0.6734669095324833 prot_P06168 + 2-acetyllactic acid + H+ + NADPH --> (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) 0.06773178437260594 +r_0096 acetohydroxy acid isomeroreductase 0.6734669095324833 prot_P06168 + 2-acetyllactic acid + H+ + NADPH --> (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) 0.06773178437260609 r_0097_EXP_1 acetolactate synthase 0.16199092088197148 prot_P07342 + 0.07346952010376134 prot_P25605 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.0 -r_0097_EXP_2 acetolactate synthase 0.08099546044098574 prot_P07342 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.06773178437260594 +r_0097_EXP_2 acetolactate synthase 0.08099546044098574 prot_P07342 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.06773178437260609 r_0099 acetyl-CoA ACP transacylase 0.2585296857817232 prot_P32463 + acetyl-CoA + ACP1 --> acetyl-ACP + coenzyme A 0.0 r_0099_REV acetyl-CoA ACP transacylase (reversible) 0.29722261474049355 prot_P32463 + acetyl-ACP + coenzyme A --> acetyl-CoA + ACP1 0.0 r_0100 acetyl-CoA C-acyltransferase (palmitoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxooctadecanoyl-CoA + coenzyme A --> acetyl-CoA + palmitoyl-CoA 0.0 @@ -130,28 +130,28 @@ r_0101 acetyl-CoA C-acyltransferase (tetracosanoyl-CoA) 0.839527027027027 prot_P r_0102 acetyl-CoA C-acyltransferase (myristoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxopalmitoyl-CoA + coenzyme A --> acetyl-CoA + myristoyl-CoA 0.0 r_0103 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.0 r_0103_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA 0.0 -r_0104 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.022347724063872188 +r_0104 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.022347724063862068 r_0104_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA 0.0 -r_0105 acetyl-CoA C-acyltransferase (lauroyl-CoA) 0.839527027027027 prot_P27796 + 3-oxotetradecanoyl-CoA + coenzyme A --> acetyl-CoA + lauroyl-CoA 7.302847455517871e-06 -r_0106 acetyl-CoA C-acyltransferase (octanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxodecanoyl-CoA + coenzyme A --> acetyl-CoA + octanoyl-CoA 1.9000000606814286e-05 -r_0107 acetyl-CoA C-acyltransferase (decanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxolauroyl-CoA + coenzyme A --> acetyl-CoA + decanoyl-CoA 1.9000000606814286e-05 +r_0105 acetyl-CoA C-acyltransferase (lauroyl-CoA) 0.839527027027027 prot_P27796 + 3-oxotetradecanoyl-CoA + coenzyme A --> acetyl-CoA + lauroyl-CoA 0.0 +r_0106 acetyl-CoA C-acyltransferase (octanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxodecanoyl-CoA + coenzyme A --> acetyl-CoA + octanoyl-CoA 0.0 +r_0107 acetyl-CoA C-acyltransferase (decanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxolauroyl-CoA + coenzyme A --> acetyl-CoA + decanoyl-CoA 0.0 r_0108 acetyl-Coa carboxylase 8.46937908496732 prot_P32874 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.0 -r_0109 acetyl-CoA carboxylase, reaction 2.608229839040149 prot_P48445 + 8.55097579839999 prot_Q00955 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.11855172683206953 +r_0109 acetyl-CoA carboxylase, reaction 2.608229839040149 prot_P48445 + 8.55097579839999 prot_Q00955 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.11839681828545526 r_0111 acetyl-CoA hydrolase 2.24640342822161 prot_P32316 + acetyl-CoA + H2O --> acetate + coenzyme A + H+ 0.0 r_0112_EXP_1 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 -r_0112_EXP_2 acetyl-CoA synthetase 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.3145977928534833 -r_0113 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 1.0754243780952912 +r_0112_EXP_2 acetyl-CoA synthetase 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.37251645368397396 +r_0113 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.18452644488299888 r_0114 acetyl-CoA synthetase nuclear 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 r_0115 acetylglutamate kinase 3.4224025974025976 prot_Q01217 + ATP + N-acetyl-L-glutamate --> ADP + N-acetyl-L-gamma-glutamyl phosphate 0.0194296205196944 r_0116_EXP_1 acid phosphatase (secreted) 12.535888834043245 prot_P00635 + FMN + H2O --> phosphate + riboflavin 0.0 r_0116_EXP_2 acid phosphatase (secreted) 2.079636552290633 prot_P35842 + FMN + H2O --> phosphate + riboflavin 0.0 r_0116_EXP_3 acid phosphatase (secreted) 8.09317955304032 prot_P24031 + FMN + H2O --> phosphate + riboflavin 0.0 r_0116_EXP_4 acid phosphatase (secreted) 2.0162205390505443 prot_P38693 + FMN + H2O --> phosphate + riboflavin 0.0 -r_0117 aconitase 356.0740740740741 prot_Q12428 + 2-methylcitrate --> (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid 0.0 +r_0117 aconitase 356.0740740740741 prot_Q12428 + 2-methylcitrate --> (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid 1.9999991326180577e-05 r_0117_REV aconitase (reversible) 0.0015170737865303288 prot_Q12428 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> 2-methylcitrate 0.0 r_0118 acteylornithine transaminase 5.836456209941037 prot_P18544 + 2-acetamido-5-oxopentanoate + L-glutamate --> 2-oxoglutarate + N(2)-acetyl-L-ornithine 0.0194296205196944 r_0119 acyl carrier protein synthase 1.9814484126984127 prot_Q12036 + coenzyme A + H2O --> adenosine 3',5'-bismonophosphate + 2.0 H+ + pantetheine 4'-phosphate 0.0 -r_0120 acyl-CoA oxidase (decanoyl-CoA) 15.258169934640524 prot_P13711 + decanoyl-CoA + oxygen --> hydrogen peroxide + trans-dec-2-enoyl-CoA 1.9000000606814286e-05 +r_0120 acyl-CoA oxidase (decanoyl-CoA) 15.258169934640524 prot_P13711 + decanoyl-CoA + oxygen --> hydrogen peroxide + trans-dec-2-enoyl-CoA 0.0 r_0121 acyl-CoA oxidase (dodecanoyl-CoA) 2.7176949941792783 prot_P13711 + lauroyl-CoA + oxygen --> hydrogen peroxide + trans-dodec-2-enoyl-CoA 0.0 r_0122 acyl-CoA oxidase (hexacosanoyl-CoA) 2.7176949941792783 prot_P13711 + hexacosanoyl-CoA + oxygen --> hydrogen peroxide + trans-hexacos-2-enoyl-CoA 0.0 r_0123 acyl-CoA oxidase (hexadecanoyl-CoA) 0.2992948717948718 prot_P13711 + oxygen + palmitoyl-CoA --> hexadec-2-enoyl-CoA + hydrogen peroxide 0.0 @@ -160,7 +160,7 @@ r_0125 acyl-CoA oxidase (tetradecanoyl-CoA) 2.7176949941792783 prot_P13711 + myr r_0126 acyl-CoA:sterol acyltransferase (oleoyl-CoA:episterol), ER membrane 65.94767724903261 prot_P25628 + oleoyl-CoA + episterol --> coenzyme A + episteryl oleate 0.0 r_0126_REV acyl-CoA:sterol acyltransferase (oleoyl-CoA:episterol), ER membrane (reversible) 3.9740642147807406 prot_P25628 + coenzyme A + episteryl oleate --> oleoyl-CoA + episterol 0.0 r_0127_EXP_1 acyl-CoA:sterol acyltransferase (oleoyl-CoA:ergosterol), ER membrane 64.38822905167784 prot_P25628 + oleoyl-CoA + ergosterol --> coenzyme A + ergosteryl oleate 0.0 -r_0127_EXP_2 acyl-CoA:sterol acyltransferase (oleoyl-CoA:ergosterol), ER membrane 20.961725602079696 prot_P53629 + oleoyl-CoA + ergosterol --> coenzyme A + ergosteryl oleate 0.0002806196932011564 +r_0127_EXP_2 acyl-CoA:sterol acyltransferase (oleoyl-CoA:ergosterol), ER membrane 20.961725602079696 prot_P53629 + oleoyl-CoA + ergosterol --> coenzyme A + ergosteryl oleate 0.0002806196932010937 r_0128 acyl-CoA:sterol acyltransferase (oleoyl-CoA:fecosterol), ER membrane 65.94767724903261 prot_P25628 + oleoyl-CoA + fecosterol --> coenzyme A + fecosteryl oleate 0.0 r_0128_REV acyl-CoA:sterol acyltransferase (oleoyl-CoA:fecosterol), ER membrane (reversible) 3.9740642147807406 prot_P25628 + coenzyme A + fecosteryl oleate --> oleoyl-CoA + fecosterol 0.0 r_0129 acyl-CoA:sterol acyltransferase (oleoyl-CoA:lanosterol), ER membrane 57.54568671113769 prot_P25628 + oleoyl-CoA + lanosterol --> coenzyme A + lanosteryl oleate 0.0 @@ -169,7 +169,7 @@ r_0130_REV acyl-CoA:sterol acyltransferase (oleoyl-CoA:zymosterol), ER membrane r_0131 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:episterol), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + episterol --> coenzyme A + episteryl palmitoleate 0.0 r_0131_REV acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:episterol), ER membrane (reversible) 3.9740642147807406 prot_P25628 + coenzyme A + episteryl palmitoleate --> palmitoleoyl-CoA(4-) + episterol 0.0 r_0132_EXP_1 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane 64.38822905167784 prot_P25628 + palmitoleoyl-CoA(4-) + ergosterol --> coenzyme A + ergosteryl palmitoleate 0.0 -r_0132_EXP_2 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + ergosterol --> coenzyme A + ergosteryl palmitoleate 0.0007820180262607629 +r_0132_EXP_2 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + ergosterol --> coenzyme A + ergosteryl palmitoleate 0.0007820180262608282 r_0132_REV_EXP_1 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane (reversible) 2.799291523044568 prot_P25628 + coenzyme A + ergosteryl palmitoleate --> palmitoleoyl-CoA(4-) + ergosterol 0.0 r_0132_REV_EXP_2 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane (reversible) 1.8538886920531146 prot_P53629 + coenzyme A + ergosteryl palmitoleate --> palmitoleoyl-CoA(4-) + ergosterol 0.0 r_0133 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:fecosterol), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + fecosterol --> coenzyme A + fecosteryl palmitoleate 0.0 @@ -184,30 +184,30 @@ r_0138 adenine deaminase 2.0017676767676766 prot_P53909 + adenine + H+ + H2O --> r_0139_EXP_1 adenine phosphoribosyltransferase 0.5950339406931047 prot_P36973 + adenine + PRPP --> AMP + diphosphate 0.0 r_0139_EXP_2 adenine phosphoribosyltransferase 0.6129272359175896 prot_P49435 + adenine + PRPP --> AMP + diphosphate 0.0 r_0140 adenosine deaminase 2.0017676767676766 prot_P53909 + adenosine + H+ + H2O --> ammonium + inosine 0.0 -r_0142 adenosine kinase 0.3962091503267974 prot_P47143 + adenosine + ATP --> ADP + AMP + H+ 0.01636957964154126 +r_0142 adenosine kinase 0.3962091503267974 prot_P47143 + adenosine + ATP --> ADP + AMP + H+ 0.016369579641541253 r_0143 adenosine monophosphate deaminase 21.282895302745313 prot_P15274 + AMP + H+ + H2O --> ammonium + IMP 0.0 -r_0144 adenosylhomocysteinase 0.023732367149758453 prot_P39954 + H2O + S-adenosyl-L-homocysteine --> adenosine + L-homocysteine 0.013930832144838404 +r_0144 adenosylhomocysteinase 0.023732367149758453 prot_P39954 + H2O + S-adenosyl-L-homocysteine --> adenosine + L-homocysteine 0.013930832144838397 r_0145 adenosylmethionine decarboxylase 7.554248366013072 prot_P21182 + H+ + S-adenosyl-L-methionine --> carbon dioxide + S-adenosylmethioninamine 0.0024387474967028553 r_0146 adenosylmethionine-8-amino-7-oxononanoate transaminase 14.919166666666667 prot_P50277 + 8-amino-7-oxononanoate + S-adenosyl-L-methionine --> 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate 0.0 r_0146_REV adenosylmethionine-8-amino-7-oxononanoate transaminase (reversible) 14.919166666666667 prot_P50277 + 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate --> 8-amino-7-oxononanoate + S-adenosyl-L-methionine 0.0 r_0147 adenylate cyclase 0.013758091787439614 prot_P08678 + ATP --> 3',5'-cyclic AMP + diphosphate 0.0 r_0148_EXP_1 adenylate kinase 0.007176741835638936 prot_Q12055 + AMP + ATP --> 2.0 ADP 0.33284577502689433 -r_0148_EXP_2 adenylate kinase 0.007660602615122228 prot_P07170 + AMP + ATP --> 2.0 ADP 0.5520697736069886 -r_0149 adenylate kinase 10.450950897581233 prot_P26364 + AMP + ATP --> 2.0 ADP 0.8593402432918792 -r_0150 adenylate kinase (GTP) 10.495327582667667 prot_P26364 + AMP + GTP --> ADP + GDP 0.21608413480341207 +r_0148_EXP_2 adenylate kinase 0.007660602615122228 prot_P07170 + AMP + ATP --> 2.0 ADP 0.6100074344380895 +r_0149 adenylate kinase 10.450950897581233 prot_P26364 + AMP + ATP --> 2.0 ADP 0.0 +r_0150 adenylate kinase (GTP) 10.495327582667667 prot_P26364 + AMP + GTP --> ADP + GDP 0.18452644488299888 r_0150_REV adenylate kinase (GTP) (reversible) 2.5045140533551153 prot_P26364 + ADP + GDP --> AMP + GTP 0.0 -r_0151 adenylosuccinate lyase (AICAR) 0.04493076162215628 prot_Q05911 + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole --> AICAR + fumarate 0.010240306385252815 -r_0152 adenylosuccinate lyase 0.04493076162215628 prot_Q05911 + adenylo-succinate --> AMP + fumarate 0.01379719194741065 +r_0151 adenylosuccinate lyase (AICAR) 0.04493076162215628 prot_Q05911 + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole --> AICAR + fumarate 0.010240306385252796 +r_0152 adenylosuccinate lyase 0.04493076162215628 prot_Q05911 + adenylo-succinate --> AMP + fumarate 0.013797191947410603 r_0152_REV adenylosuccinate lyase (reversible) 5.221264367816092 prot_Q05911 + AMP + fumarate --> adenylo-succinate 0.0 -r_0153 adenylosuccinate synthase 2.4383333333333335 prot_P80210 + GTP + IMP + L-aspartate --> adenylo-succinate + GDP + 2.0 H+ + phosphate 0.01379719194741065 -r_0154 adenylyl-sulfate kinase 1.4558080808080807 prot_Q02196 + 5'-adenylyl sulfate + ATP --> 3'-phospho-5'-adenylyl sulfate + ADP + H+ 0.011924916613574123 +r_0153 adenylosuccinate synthase 2.4383333333333335 prot_P80210 + GTP + IMP + L-aspartate --> adenylo-succinate + GDP + 2.0 H+ + phosphate 0.013797191947410603 +r_0154 adenylyl-sulfate kinase 1.4558080808080807 prot_Q02196 + 5'-adenylyl sulfate + ATP --> 3'-phospho-5'-adenylyl sulfate + ADP + H+ 0.011924916613574275 r_0155 ADP-ribose 2,3-cyclic phosphodiesterase 0.00789952718676123 prot_P53314 + 2',3'-cyclic AMP + H2O --> adenosine 2'-phosphate + H+ 0.0 r_0156 alanine glyoxylate aminotransferase 0.08886132315521629 prot_P43567 + glyoxylate + L-alanine --> L-glycine + pyruvate 0.0 r_0157 alanyl-tRNA synthetase 0.25476620370370373 prot_P40825 + ATP + L-alanine + tRNA(Ala) --> Ala-tRNA(Ala) + AMP + diphosphate 0.0347736630768556 r_0158_EXP_1 alcohol acetyltransferase (2-methylbutanol) 0.00442002285061411 prot_P53296 + 2-methylbutanol + acetyl-CoA --> 2-methylbutyl acetate + coenzyme A 0.0 r_0158_EXP_2 alcohol acetyltransferase (2-methylbutanol) 0.004358469008854613 prot_P40353 + 2-methylbutanol + acetyl-CoA --> 2-methylbutyl acetate + coenzyme A 0.0 r_0159_EXP_1 alcohol acetyltransferase (ethanol) 0.00442002285061411 prot_P53296 + acetyl-CoA + ethanol --> coenzyme A + ethyl acetate 0.0 -r_0159_EXP_2 alcohol acetyltransferase (ethanol) 0.004358469008854613 prot_P40353 + acetyl-CoA + ethanol --> coenzyme A + ethyl acetate 0.16778232905888193 +r_0159_EXP_2 alcohol acetyltransferase (ethanol) 0.004358469008854613 prot_P40353 + acetyl-CoA + ethanol --> coenzyme A + ethyl acetate 0.12158141345131043 r_0160_EXP_1 alcohol acetyltransferase (isoamyl alcohol) 0.00442002285061411 prot_P53296 + acetyl-CoA + isoamylol --> coenzyme A + isoamyl acetate 0.0 r_0160_EXP_2 alcohol acetyltransferase (isoamyl alcohol) 0.004358469008854613 prot_P40353 + acetyl-CoA + isoamylol --> coenzyme A + isoamyl acetate 0.0 r_0161_EXP_1 alcohol acetyltransferase (isobutyl alcohol) 0.00442002285061411 prot_P53296 + acetyl-CoA + isobutanol --> coenzyme A + isobutyl acetate 0.0 @@ -219,7 +219,7 @@ r_0164_EXP_1 alcohol dehydrogenase (glycerol, NADP) 1.4852564102564103 prot_Q124 r_0164_EXP_2 alcohol dehydrogenase (glycerol, NADP) 60.65196078431372 prot_P38715 + D-glyceraldehyde + H+ + NADPH --> glycerol + NADP(+) 0.0 r_0165_EXP_1 mitochondrial alcohol dehydrogenase 0.012698148148148148 prot_P10127 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.0 r_0165_EXP_2 mitochondrial alcohol dehydrogenase 0.03581110330487606 prot_P07246 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.0 -r_0166_EXP_1 aldehyde dehydrogenase (2-methylbutanol, NAD) 0.006354607630660375 prot_P38113 + 2-methylbutanal + H+ + NADH --> 2-methylbutanol + NAD 0.010312095158732992 +r_0166_EXP_1 aldehyde dehydrogenase (2-methylbutanol, NAD) 0.006354607630660375 prot_P38113 + 2-methylbutanal + H+ + NADH --> 2-methylbutanol + NAD 0.0 r_0166_EXP_2 aldehyde dehydrogenase (2-methylbutanol, NAD) 0.0069274810448778975 prot_P32771 + 2-methylbutanal + H+ + NADH --> 2-methylbutanol + NAD 0.0 r_0166_EXP_3 aldehyde dehydrogenase (2-methylbutanol, NAD) 0.011373148148148148 prot_P00330 + 2-methylbutanal + H+ + NADH --> 2-methylbutanol + NAD 0.0 r_0167_EXP_1 aldehyde dehydrogenase (2-methylbutanol, NAD) 0.012698148148148148 prot_P10127 + 2-methylbutanal + H+ + NADH --> 2-methylbutanol + NAD 0.0 @@ -236,10 +236,10 @@ r_0171_EXP_1 aldehyde dehydrogenase (2-phenylethanol, NADP) 1.6815384615384616 p r_0171_EXP_2 aldehyde dehydrogenase (2-phenylethanol, NADP) 0.012227777777777778 prot_Q04894 + H+ + NADPH + phenylacetaldehyde --> 2-phenylethanol + NADP(+) 0.0 r_0172_EXP_1 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.483596214511041 prot_P47771 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 0.0 r_0172_EXP_2 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.06410300925925926 prot_P54114 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 0.0024387474967028553 -r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.3126729962399134 -r_0174 aldehyde dehydrogenase (acetylaldehyde, NAD) 1.6231765567058962 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 1.1486826521636846 +r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.3705916570704039 +r_0174 aldehyde dehydrogenase (acetylaldehyde, NAD) 1.6231765567058962 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.26809681411012504 r_0175_EXP_1 aldehyde dehydrogenase (acetylaldehyde, NADP) 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.0 -r_0175_EXP_2 aldehyde dehydrogenase (acetylaldehyde, NADP) 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.12402253206845248 +r_0175_EXP_2 aldehyde dehydrogenase (acetylaldehyde, NADP) 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.11371043690971966 r_0176 aldehyde dehydrogenase (indole-3-acetaldehyde, NAD) 2.9233283159832175 prot_P46367 + H2O + indol-3-ylacetaldehyde + NAD --> 2.0 H+ + indole-3-acetate + NADH 0.0 r_0177 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + H2O + indol-3-ylacetaldehyde + NADP(+) --> 2.0 H+ + indole-3-acetate + NADPH 0.0 r_0178_EXP_1 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 2.027300005914026 prot_P40047 + H2O + indol-3-ylacetaldehyde + NADP(+) --> 2.0 H+ + indole-3-acetate + NADPH 0.0 @@ -294,8 +294,8 @@ r_0199_EXP_1 amidase 0.002363959719142646 prot_P22580 + 4-guanidinobutanamide + r_0199_EXP_2 amidase 0.002263428815277111 prot_Q03557 + 4-guanidinobutanamide + H2O --> 4-guanidinobutanoic acid + ammonium 0.0 r_0200 Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing) 0.062476381011109826 prot_standard + aminoacetone + H2O + oxygen --> ammonium + hydrogen peroxide + methylglyoxal 0.0 r_0201 Aminobutyraldehyde dehydrogenase 6.571504396261395 prot_P46367 + 4-aminobutanal + H2O + NAD --> gamma-aminobutyrate + 2.0 H+ + NADH 0.0 -r_0202 anthranilate phosphoribosyltransferase 2.8570423609142406 prot_P07285 + anthranilate + PRPP --> diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate 0.007308031687142077 -r_0203 anthranilate synthase 0.11426731078904992 prot_P00899 + 0.1076670692431562 prot_P00937 + chorismate + L-glutamine --> anthranilate + H+ + L-glutamate + pyruvate 0.004463981443245845 +r_0202 anthranilate phosphoribosyltransferase 2.8570423609142406 prot_P07285 + anthranilate + PRPP --> diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate 0.0073080316871415064 +r_0203 anthranilate synthase 0.11426731078904992 prot_P00899 + 0.1076670692431562 prot_P00937 + chorismate + L-glutamine --> anthranilate + H+ + L-glutamate + pyruvate 0.004463981443244731 r_0204 Ap4A hydrolase 0.16307795442894646 prot_P49775 + H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate --> 2.0 ADP + 2.0 H+ 0.0 r_0204_REV Ap4A hydrolase (reversible) 0.1607002693067822 prot_P49775 + 2.0 ADP + 2.0 H+ --> H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate 0.0 r_0205 arabinose reductase 0.01001051779935275 prot_P38715 + H+ + L-arabinose + NADPH --> L-arabinitol + NADP(+) 0.0 @@ -310,50 +310,50 @@ r_0211_EXP_1 asparagine synthase (glutamine-hydrolysing) 1.9523939064200218 prot r_0211_EXP_2 asparagine synthase (glutamine-hydrolysing) 1.948676097207109 prot_P49089 + ATP + H2O + L-aspartate + L-glutamine --> AMP + diphosphate + H+ + L-asparagine + L-glutamate 0.019146806720785902 r_0212 Asparaginyl-tRNA synthetase 1.710863586358636 prot_P38707 + ATP + L-asparagine + tRNA(Asn) --> AMP + Asn-tRNA(Asn) + diphosphate 0.019146806720785902 r_0213 asparaginyl-tRNA synthetase, miotchondrial 1.5617436743674367 prot_P25345 + ATP + L-asparagine + tRNA(Asn) --> AMP + Asn-tRNA(Asn) + diphosphate 0.0 -r_0214 aspartate carbamoyltransferase 0.1632300826005862 prot_P07259 + carbamoyl phosphate + L-aspartate --> H+ + N-carbamoyl-L-aspartate + phosphate 0.010726833614579987 -r_0215 aspartate kinase 0.0711086637298091 prot_P10869 + ATP + L-aspartate --> 4-phospho-L-aspartate + ADP 0.03544209944340998 +r_0214 aspartate carbamoyltransferase 0.1632300826005862 prot_P07259 + carbamoyl phosphate + L-aspartate --> H+ + N-carbamoyl-L-aspartate + phosphate 0.01072683361457999 +r_0215 aspartate kinase 0.0711086637298091 prot_P10869 + ATP + L-aspartate --> 4-phospho-L-aspartate + ADP 0.03544209944341013 r_0216 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.0 -r_0216_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.13284515615360928 +r_0216_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.13281885330554702 r_0217 aspartate transaminase 0.021473880597014924 prot_Q01802 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.0 -r_0218 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 2.630284806233215e-05 +r_0218 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.0 r_0218_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.0 -r_0219 aspartate-semialdehyde dehydrogenase 26.415673633916466 prot_P13663 + 4-phospho-L-aspartate + H+ + NADPH --> L-aspartate 4-semialdehyde + NADP(+) + phosphate 0.03544209944340998 +r_0219 aspartate-semialdehyde dehydrogenase 26.415673633916466 prot_P13663 + 4-phospho-L-aspartate + H+ + NADPH --> L-aspartate 4-semialdehyde + NADP(+) + phosphate 0.03544209944341013 r_0220 Aspartyl-tRNA synthetase 0.7351388888888889 prot_P04802 + ATP + L-aspartate + tRNA(Asp) --> AMP + Asp-tRNA(Asp) + diphosphate 0.0240359946744132 r_0221 Aspartyl-tRNA synthetase 0.8733912037037037 prot_P15179 + ATP + L-aspartate + tRNA(Asp) --> AMP + Asp-tRNA(Asp) + diphosphate 0.0 r_0222 ATP adenylyltransferase 0.10660011574074074 prot_P22108 + ADP + ATP + H+ --> P(1),P(4)-bis(5'-adenosyl) tetraphosphate + phosphate 0.0 r_0223 ATP adenylyltransferase 0.10559317129629629 prot_P16550 + ADP + GTP + H+ --> P1-(5'-adenosyl),P4-(5'-guanosyl) tetraphosphate + phosphate 0.0 r_0224 ATP adenylyltransferase 0.10559317129629629 prot_P16550 + GDP + GTP + H+ --> P(1),P(4)-bis(5'-guanosyl) tetraphosphate + phosphate 0.0 r_0225 ATP phosphoribosyltransferase 0.8298868312757202 prot_P00498 + ATP + PRPP --> 5-phosphoribosyl-ATP + diphosphate 0.008356708763266002 -r_0226 ATP synthase 0.5394232482136998 prot_P00830 + 0.09548902616935218 prot_P00854 + 0.019105024583592853 prot_P00856 + 0.08835499603456501 prot_P05626 + 0.5769704298154636 prot_P07251 + 0.07486465662145093 prot_P09457 + 0.022127306899204155 prot_P21306 + 0.06500696272775239 prot_P30902 + 0.11272358287031914 prot_P38077 + 0.25461333861919777 prot_P61829 + 0.0356898398095424 prot_P81449 + 0.021946823156143762 prot_P81450 + 0.024722991276672712 prot_P81451 + 0.03712058366362115 prot_Q06405 + 0.05585151467068882 prot_Q12165 + 0.04240055352878791 prot_Q12233 + 0.04636135130831326 prot_Q12349 + ADP + 3.0 H+ + phosphate --> ATP + 2.0 H+ + H2O 8.485239449571491 +r_0226 ATP synthase 0.028401930104729925 prot_P00830 + 0.005027726661784965 prot_P00854 + 0.0010059254484659976 prot_P00856 + 0.004652102834068531 prot_P05626 + 0.03037887943165331 prot_P07251 + 0.0039418040503784385 prot_P09457 + 0.0011650558740993167 prot_P21306 + 0.0034227727815375154 prot_P30902 + 0.005935167482008843 prot_P38077 + 0.013406004044396558 prot_P61829 + 0.0018791558188794555 prot_P81449 + 0.0011555529713742 prot_P81450 + 0.0013017248932914508 prot_P81451 + 0.0019544879204821996 prot_Q06405 + 0.0029407164432997735 prot_Q12165 + 0.002232491020204252 prot_Q12233 + 0.0024410365400081785 prot_Q12349 + ADP + 3.0 H+ + phosphate --> ATP + 2.0 H+ + H2O 9.063205492092886 r_0226_REV ATP synthase (reversible) 0.3805138888888889 prot_P00830 + 0.06735879629629629 prot_P00854 + 0.013476851851851853 prot_P00856 + 0.06232638888888889 prot_P05626 + 0.407 prot_P07251 + 0.05281018518518518 prot_P09457 + 0.015608796296296296 prot_P21306 + 0.045856481481481484 prot_P30902 + 0.0795162037037037 prot_P38077 + 0.17960648148148148 prot_P61829 + 0.025175925925925925 prot_P81449 + 0.015481481481481481 prot_P81450 + 0.017439814814814814 prot_P81451 + 0.026185185185185186 prot_Q06405 + 0.03939814814814815 prot_Q12165 + 0.029909722222222223 prot_Q12233 + 0.03270370370370371 prot_Q12349 + ATP + 2.0 H+ + H2O --> ADP + 3.0 H+ + phosphate 0.0 r_0227_EXP_1 ATPase, plasma membrane 4.61199074074074 prot_P05030 + 0.20837962962962964 prot_P32903 + 0.22444444444444445 prot_P40975 + ATP + H2O --> ADP + H+ + phosphate 0.0 r_0227_EXP_2 ATPase, plasma membrane 4.730185185185185 prot_P19657 + 0.20837962962962964 prot_P32903 + 0.22444444444444445 prot_P40975 + ATP + H2O --> ADP + H+ + phosphate 0.0 -r_0227_EXP_3 ATPase, plasma membrane 0.023208010335917312 prot_P40009 + ATP + H2O --> ADP + H+ + phosphate 0.5569386307739062 +r_0227_EXP_3 ATPase, plasma membrane 0.023208010335917312 prot_P40009 + ATP + H2O --> ADP + H+ + phosphate 0.6513726938538268 r_0228 beta-1,4 mannosyltransferase 63.94951949233543 prot_P16661 + GDP-alpha-D-mannose + N,N'-diacetylchitobiosyldiphosphodolichol --> beta-D-mannosyldiacetylchitobiosyldiphosphodolichol + GDP + H+ 0.0 r_0229 biotin synthase 0.8370103916866507 prot_P32451 + dethiobiotin + polysulphur --> biotin + 2.0 H+ 0.0 r_0229_REV biotin synthase (reversible) 0.8370103916866507 prot_P32451 + biotin + 2.0 H+ --> dethiobiotin + polysulphur 0.0 r_0230 biotin-[acetyl-CoA-carboxylase] ligase 4.713765432098766e-05 prot_P48445 + ATP + biotin + H+ --> biotinyl-5'-AMP + diphosphate 0.0 -r_0231 C-14 sterol reductase 4.194445624507709 prot_P32462 + 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H+ + NADPH --> 14-demethyllanosterol + NADP(+) 0.003724620677312031 -r_0233 C-22 sterol desaturase (NADP) 100.21895424836602 prot_P54781 + ergosta-5,7,24(28)-trien-3beta-ol + H+ + NADPH + oxygen --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2.0 H2O + NADP(+) 0.0004991467112704911 -r_0234 C-3 sterol dehydrogenase 3.093923129380329 prot_P53199 + NADP(+) + zymosterol intermediate 1c --> carbon dioxide + NADPH + zymosterol intermediate 2 0.003724620677312031 -r_0235 C-3 sterol dehydrogenase (4-methylzymosterol) 8.806624430682128 prot_P53199 + 4beta-methylzymosterol-4alpha-carboxylic acid + NAD --> 3-dehydro-4-methylzymosterol + carbon dioxide + NADH 0.003724620677312031 -r_0236 C-3 sterol keto reductase (4-methylzymosterol) 15.116057838660579 prot_Q12452 + 3-dehydro-4-methylzymosterol + H+ + NADPH --> 4alpha-methylzymosterol + NADP(+) 0.003724620677312031 -r_0237 C-3 sterol keto reductase (zymosterol) 15.116057838660579 prot_Q12452 + H+ + NADPH + zymosterol intermediate 2 --> NADP(+) + zymosterol 0.003724620677312031 -r_0238 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + 4alpha-methylzymosterol + H+ + NADPH + oxygen --> H2O + NADP(+) + zymosterol intermediate 1a 0.003724620677312031 -r_0239 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + H+ + NADPH + oxygen + zymosterol intermediate 1a --> 2.0 H2O + NADP(+) + zymosterol intermediate 1b 0.003724620677312031 -r_0240 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + NADPH + oxygen + zymosterol intermediate 1b --> H2O + NADP(+) + zymosterol intermediate 1c 0.003724620677312031 -r_0241 C-4 sterol methyl oxidase (4,4-dimethylzymosterol) 0.511770482603816 prot_P53045 + 14-demethyllanosterol + 5.0 H+ + 3.0 oxygen + 6.0 ferrocytochrome b5 --> 4beta-methylzymosterol-4alpha-carboxylic acid + 4.0 H2O + 6.0 ferricytochrome b5 0.003724620677312031 -r_0242 C-5 sterol desaturase 24.953439493862604 prot_P32353 + episterol + H+ + NADPH + oxygen --> ergosta-5,7,24(28)-trien-3beta-ol + 2.0 H2O + NADP(+) 0.0004991467112704911 -r_0243 C-8 sterol isomerase 11.181301444435384 prot_P32352 + fecosterol --> episterol 0.0004991467112704911 -r_0244 C-s24 sterol reductase 1.5624148864343401 prot_P25340 + ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + NADPH --> ergosterol + NADP(+) 0.003720927744308719 +r_0231 C-14 sterol reductase 4.194445624507709 prot_P32462 + 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H+ + NADPH --> 14-demethyllanosterol + NADP(+) 0.0037246206773103446 +r_0233 C-22 sterol desaturase (NADP) 100.21895424836602 prot_P54781 + ergosta-5,7,24(28)-trien-3beta-ol + H+ + NADPH + oxygen --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2.0 H2O + NADP(+) 0.0 +r_0234 C-3 sterol dehydrogenase 3.093923129380329 prot_P53199 + NADP(+) + zymosterol intermediate 1c --> carbon dioxide + NADPH + zymosterol intermediate 2 0.0037246206773103446 +r_0235 C-3 sterol dehydrogenase (4-methylzymosterol) 8.806624430682128 prot_P53199 + 4beta-methylzymosterol-4alpha-carboxylic acid + NAD --> 3-dehydro-4-methylzymosterol + carbon dioxide + NADH 0.0037246206773103446 +r_0236 C-3 sterol keto reductase (4-methylzymosterol) 15.116057838660579 prot_Q12452 + 3-dehydro-4-methylzymosterol + H+ + NADPH --> 4alpha-methylzymosterol + NADP(+) 0.0037246206773103446 +r_0237 C-3 sterol keto reductase (zymosterol) 15.116057838660579 prot_Q12452 + H+ + NADPH + zymosterol intermediate 2 --> NADP(+) + zymosterol 0.0037246206773103446 +r_0238 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + 4alpha-methylzymosterol + H+ + NADPH + oxygen --> H2O + NADP(+) + zymosterol intermediate 1a 0.0037246206773103446 +r_0239 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + H+ + NADPH + oxygen + zymosterol intermediate 1a --> 2.0 H2O + NADP(+) + zymosterol intermediate 1b 0.0037246206773103446 +r_0240 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + NADPH + oxygen + zymosterol intermediate 1b --> H2O + NADP(+) + zymosterol intermediate 1c 0.0037246206773103446 +r_0241 C-4 sterol methyl oxidase (4,4-dimethylzymosterol) 0.511770482603816 prot_P53045 + 14-demethyllanosterol + 5.0 H+ + 3.0 oxygen + 6.0 ferrocytochrome b5 --> 4beta-methylzymosterol-4alpha-carboxylic acid + 4.0 H2O + 6.0 ferricytochrome b5 0.0037246206773103446 +r_0242 C-5 sterol desaturase 24.953439493862604 prot_P32353 + episterol + H+ + NADPH + oxygen --> ergosta-5,7,24(28)-trien-3beta-ol + 2.0 H2O + NADP(+) 0.0 +r_0243 C-8 sterol isomerase 11.181301444435384 prot_P32352 + fecosterol --> episterol 0.0 +r_0244 C-s24 sterol reductase 1.5624148864343401 prot_P25340 + ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + NADPH --> ergosterol + NADP(+) 0.003720927744308722 r_0249 CAAX farnesyltransferase 4.1518225763666585 prot_P22007 + 3.231511956720494 prot_P29703 + 4-hydroxybenzoate + nonaprenyl diphosphate --> diphosphate + nonaprenyl 4-hydroxybenzoate 0.0 r_0250_EXP_1 carbamoyl-phosphate synthase (glutamine-hydrolysing) 0.01089245390373571 prot_P07259 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.03015645413427439 r_0250_EXP_2 carbamoyl-phosphate synthase (glutamine-hydrolysing) 3.661790780141844 prot_P03965 + 1.34048463356974 prot_P07258 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.0 r_0252_EXP_1 carnitine O-acetyltransferase 0.016201655041376033 prot_P80235 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 r_0252_EXP_2 carnitine O-acetyltransferase 0.05053501564945227 prot_P40017 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 -r_0253 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0001739085472208489 -r_0254 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + coenzyme A + O-acetylcarnitine --> (R)-carnitine + acetyl-CoA 0.0001739085472208489 -r_0255 catalase 6.339124460149195e-06 prot_P06115 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0 +r_0253 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 +r_0254 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + coenzyme A + O-acetylcarnitine --> (R)-carnitine + acetyl-CoA 0.0 +r_0255 catalase 6.339124460149195e-06 prot_P06115 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0012193737483514276 r_0256 catalase 5.747447978013349e-06 prot_P15202 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0 r_0259 ceramide-1 hydroxylase (24C) 0.035359375 prot_P38992 + ceramide-1 (C24) + H+ + NADPH + oxygen --> ceramide-2 (C24) + H2O + NADP(+) 0.0 r_0260 ceramide-1 hydroxylase (24C) 0.03895920138888889 prot_Q03529 + ceramide-1 (C24) + H+ + NADPH + oxygen --> ceramide-2' (C24) + H2O + NADP(+) 0.0 @@ -372,10 +372,10 @@ r_0271_EXP_2 chitin deacetylase 0.01794357473933983 prot_Q06703 + chitin + H2O - r_0272_EXP_1 chitin synthase 80.72709323101475 prot_P29465 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0 r_0272_EXP_2 chitin synthase 13.190119547029806 prot_P14180 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0023610000000000003 r_0272_EXP_3 chitin synthase 188.53265572369114 prot_P08004 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0 -r_0273 choline kinase 7.224074074074074 prot_P20485 + ATP + choline --> ADP + choline phosphate + H+ 0.003399616352539276 -r_0274 choline phosphate cytididyltransferase 0.4121287954621288 prot_P13259 + choline phosphate + CTP + H+ --> CDP-choline + diphosphate 0.003399616352539276 -r_0278 chorismate mutase 0.02288935056940597 prot_P32178 + chorismate --> prephenate 0.041472874477800736 -r_0279 chorismate synthase 0.3336437908496732 prot_P28777 + 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid --> chorismate + phosphate 0.04594319592130103 +r_0273 choline kinase 7.224074074074074 prot_P20485 + ATP + choline --> ADP + choline phosphate + H+ 0.0033996163525392663 +r_0274 choline phosphate cytididyltransferase 0.4121287954621288 prot_P13259 + choline phosphate + CTP + H+ --> CDP-choline + diphosphate 0.0033996163525392663 +r_0278 chorismate mutase 0.02288935056940597 prot_P32178 + chorismate --> prephenate 0.0289821618819572 +r_0279 chorismate synthase 0.3336437908496732 prot_P28777 + 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid --> chorismate + phosphate 0.0334524833254565 r_0280 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.0 r_0280_REV cis-aconitate(3-) to isocitrate (reversible) 0.16582750582750583 prot_P19414 + isocitrate --> cis-aconitate + H2O 0.0 r_0281_EXP_1 cis-prenyltransferase step 01 40.954572225982666 prot_P35196 + farnesyl diphosphate + isopentenyl diphosphate --> diphosphate + geranylgeranyl diphosphate 0.0 @@ -420,28 +420,28 @@ r_0298_EXP_1 cis-prenyltransferase step 18 40.954572225982666 prot_P35196 + icos r_0298_EXP_2 cis-prenyltransferase step 18 30.078354060470264 prot_Q03175 + icosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + henicosaprenyl diphosphate 0.0 r_0299_EXP_1 cis-prenyltransferase step 19 40.954572225982666 prot_P35196 + henicosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + docosaprenyl diphosphate 0.0 r_0299_EXP_2 cis-prenyltransferase step 19 30.078354060470264 prot_Q03175 + henicosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + docosaprenyl diphosphate 0.0 -r_0300_EXP_1 citrate synthase 0.10489895415585436 prot_P00890 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 1.269587097829964 +r_0300_EXP_1 citrate synthase 0.10489895415585436 prot_P00890 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 1.260812446021116 r_0300_EXP_2 citrate synthase 0.10578556263269638 prot_P43635 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.0 r_0301 citrate synthase, peroxisomal 1.275124007936508 prot_P08679 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.0 r_0302 citrate to cis-aconitate(3-) 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.0 r_0302_REV citrate to cis-aconitate(3-) (reversible) 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> citrate 0.0 -r_0303 citrate to cis-aconitate(3-), cytoplasmic 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 1.269587097829964 +r_0303 citrate to cis-aconitate(3-), cytoplasmic 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 1.260812446021116 r_0303_REV citrate to cis-aconitate(3-), cytoplasmic (reversible) 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> citrate 0.0 r_0304 coproporphyrinogen oxidase (O2 required) 616.2091503267974 prot_P11353 + coproporphyrinogen III + 2.0 H+ + oxygen --> 2.0 carbon dioxide + 2.0 H2O + protoporphyrinogen 0.0 r_0306_EXP_1 CTP synthase (glutamine) 0.5634796238244514 prot_P28274 + ATP + H2O + L-glutamine + UTP --> ADP + CTP + 2.0 H+ + L-glutamate + phosphate 0.0 r_0306_EXP_2 CTP synthase (glutamine) 0.5617467781260884 prot_P38627 + ATP + H2O + L-glutamine + UTP --> ADP + CTP + 2.0 H+ + L-glutamate + phosphate 0.0 r_0307_EXP_1 CTP synthase (NH3) 0.5634796238244514 prot_P28274 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.0 -r_0307_EXP_2 CTP synthase (NH3) 0.5617467781260884 prot_P38627 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.004927623923664108 +r_0307_EXP_2 CTP synthase (NH3) 0.5617467781260884 prot_P38627 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.004927623923664103 r_0308_EXP_1 cystathionine b-lyase 11.285409035409035 prot_P43623 + H2O + L-cystathionine --> ammonium + L-homocysteine + pyruvate 0.0 r_0308_EXP_2 cystathionine b-lyase 15.820512820512821 prot_P53101 + H2O + L-cystathionine --> ammonium + L-homocysteine + pyruvate 0.0 -r_0309 cystathionine beta-synthase 0.7237984496124031 prot_P32582 + L-homocysteine + L-serine --> H2O + L-cystathionine 0.0037750499662957075 -r_0310 cystathionine g-lyase 6.5288520564763655 prot_P31373 + H2O + L-cystathionine --> 2-oxobutanoate + ammonium + L-cysteine 0.0037750499662957075 +r_0309 cystathionine beta-synthase 0.7237984496124031 prot_P32582 + L-homocysteine + L-serine --> H2O + L-cystathionine 0.003775049966295859 +r_0310 cystathionine g-lyase 6.5288520564763655 prot_P31373 + H2O + L-cystathionine --> 2-oxobutanoate + ammonium + L-cysteine 0.003775049966295859 r_0311 cystathionine gamma-synthase 0.16609504132231406 prot_P47164 + L-cysteine + O-acetyl-L-homoserine --> acetate + H+ + L-cystathionine 0.0 r_0312 cysteine synthase 0.05827586206896552 prot_P06106 + hydrogen sulfide + O-acetyl-L-serine --> acetate + L-cysteine 0.0 r_0313 cysteinyl-tRNA synthetase 0.1712245696400626 prot_P53852 + ATP + L-cysteine + tRNA(Cys) --> AMP + Cys-tRNA(Cys) + diphosphate 0.00375594996568427 r_0314 cytidine deaminase 0.34727251593751957 prot_Q06549 + cytidine + H+ + H2O --> ammonium + uridine 0.0 r_0315 cytidine kinase (GTP) 3.6366925064599482 prot_P27515 + cytidine + GTP --> CMP + GDP + H+ 0.0 -r_0317 cytochrome P450 lanosterol 14-alpha-demethylase (NADP) 2.53 prot_P10614 + 3.1988333333333334 prot_P16603 + 2.0 H+ + lanosterol + 3.0 NADPH + 3.0 oxygen --> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 4.0 H2O + 3.0 NADP(+) 0.003724620677312031 +r_0317 cytochrome P450 lanosterol 14-alpha-demethylase (NADP) 2.53 prot_P10614 + 3.1988333333333334 prot_P16603 + 2.0 H+ + lanosterol + 3.0 NADPH + 3.0 oxygen --> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 4.0 H2O + 3.0 NADP(+) 0.0037246206773103446 r_0318 cytosine deaminase 0.028606209150326797 prot_Q12178 + cytosine + H+ + H2O --> ammonium + uracil 0.0 r_0319 D-arabinono-1,4-lactone oxidase 0.790723019670388 prot_P54783 + D-arabinono-1,4-lactone + oxygen --> dehydro-D-arabinono-1,4-lactone + H+ + hydrogen peroxide 0.0 r_0320 D-arabinose 1-dehydrogenase (NAD) 4.371122252366052 prot_Q04212 + D-arabinose + NAD --> D-arabinono-1,4-lactone + H+ + NADH 0.0 @@ -459,7 +459,7 @@ r_0330 deoxyguanylate kinase (dGMP:ATP) 0.06369444444444444 prot_P15454 + ATP + r_0330_REV deoxyguanylate kinase (dGMP:ATP) (reversible) 0.014549492385786802 prot_P15454 + ADP + dGDP --> ATP + dGMP 0.00024000001139938803 r_0331 deoxyhypusine synthase, cytosolic/mitochondrial 66.19135802469135 prot_P38791 + H2O + spermidine + ubiquinone-6 --> 4-aminobutanal + trimethylenediamine + ubiquinol-6 0.0 r_0332 deoxyribokinase 0.214529735759604 prot_P25332 + 2-deoxy-D-ribose + ATP --> 2-deoxy-D-ribose 5-phosphate + ADP + H+ 0.0 -r_0334 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 1.9000000605489682e-05 +r_0334 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 1.9000000611588824e-05 r_0335 dethiobiotin synthase 0.18895365572826714 prot_P53630 + 7,8-diaminononanoate + ATP + carbon dioxide --> ADP + dethiobiotin + 3.0 H+ + phosphate 0.0 r_0335_REV dethiobiotin synthase (reversible) 0.14884920634920634 prot_P53630 + ADP + dethiobiotin + 3.0 H+ + phosphate --> 7,8-diaminononanoate + ATP + carbon dioxide 0.0 r_0340 dihydroceramidase 2.6755547192301745 prot_Q02896 + lignoceric acid + sphinganine --> ceramide-1 (C24) + H2O 0.0 @@ -474,14 +474,14 @@ r_0346 dihydrofolate synthase 1.4510179534077177 prot_Q12676 + 7,8-dihydropteroa r_0347 dihydroneopterin aldolase 25.866666666666667 prot_P53848 + 7,8-dihydroneopterin --> 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + glycolaldehyde 6.3400002545677125e-06 r_0348 dihydroneopterin monophosphate dephosphorylase 1.3136097495034373 prot_Q12154 + 7,8-dihydroneopterin 3'-phosphate + H2O --> 7,8-dihydroneopterin + phosphate 0.0 r_0349 dihydroorotase 5.893713450292398 prot_P20051 + (S)-dihydroorotate + H2O --> H+ + N-carbamoyl-L-aspartate 0.0 -r_0349_REV dihydroorotase (reversible) 0.17974406991260924 prot_P20051 + H+ + N-carbamoyl-L-aspartate --> (S)-dihydroorotate + H2O 0.010726833614579987 +r_0349_REV dihydroorotase (reversible) 0.17974406991260924 prot_P20051 + H+ + N-carbamoyl-L-aspartate --> (S)-dihydroorotate + H2O 0.01072683361457999 r_0350 dihydropteroate synthase 237.30886850152908 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + 4-aminobenzoate --> 7,8-dihydropteroate + H2O 6.3400002545677125e-06 r_0351 dihydropteroate synthase 237.30886850152908 prot_P53848 + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + 4-aminobenzoate --> 7,8-dihydropteroate + diphosphate 0.0 -r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.23036133098798006 prot_P39522 + (R)-2,3-dihydroxy-3-methylbutanoate --> 3-methyl-2-oxobutanoate + H2O 0.06773178437260594 -r_0353 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate) 1.419625112917796 prot_P39522 + (2R,3R)-2,3-dihydroxy-3-methylpentanoate --> (S)-3-methyl-2-oxopentanoate + H2O 0.03686112717615209 +r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.23036133098798006 prot_P39522 + (R)-2,3-dihydroxy-3-methylbutanoate --> 3-methyl-2-oxobutanoate + H2O 0.06773178437260609 +r_0353 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate) 1.419625112917796 prot_P39522 + (2R,3R)-2,3-dihydroxy-3-methylpentanoate --> (S)-3-methyl-2-oxopentanoate + H2O 0.0265490320174191 r_0354_EXP_1 dihydroxyacetone kinase 0.7185562956795263 prot_P43550 + ATP + glycerone --> ADP + dihydroxyacetone phosphate + H+ 0.0 r_0354_EXP_2 dihydroxyacetone kinase 0.719388935146637 prot_P54838 + ATP + glycerone --> ADP + dihydroxyacetone phosphate + H+ 0.0 -r_0355 dimethylallyltranstransferase 10.222979797979797 prot_P08524 + isopentenyl diphosphate + prenyl diphosphate(3-) --> diphosphate + geranyl diphosphate 0.007449241354624062 +r_0355 dimethylallyltranstransferase 10.222979797979797 prot_P08524 + isopentenyl diphosphate + prenyl diphosphate(3-) --> diphosphate + geranyl diphosphate 0.007449241354620689 r_0356 diphosphoglyceromutase 0.013314525462962964 prot_P00950 + 1,3-bisphospho-D-glycerate --> 2,3-bisphospho-D-glyceric acid + H+ 0.0 r_0356_REV diphosphoglyceromutase (reversible) 0.013314525462962964 prot_P00950 + 2,3-bisphospho-D-glyceric acid + H+ --> 1,3-bisphospho-D-glycerate 0.0 r_0357 diphosphoinositol-1,3,4,6-tetrakisphosphate diphosphohydrolase 2396.8888888888887 prot_Q99321 + 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + 3.0 H2O --> 3.0 H+ + myo-inositol 1,3,4,5,6-pentakisphosphate + 3.0 phosphate 0.0 @@ -498,7 +498,7 @@ r_0364_EXP_1 dUTP diphosphatase 0.006082204603017289 prot_P47119 + dUTP + H2O -- r_0364_EXP_2 dUTP diphosphatase 0.4429108796296296 prot_P33317 + dUTP + H2O --> diphosphate + dUMP + H+ 0.0 r_0365 endopolygalacturonase 1.7035361842105263 prot_P47180 + H2O + pectin --> D-galacturonate 0.0 r_0366_EXP_1 enolase 0.05715942028985507 prot_P0CX11 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 -r_0366_EXP_2 enolase 0.056541062801932364 prot_P00924 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 2.373773308889234 +r_0366_EXP_2 enolase 0.056541062801932364 prot_P00924 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 2.4707227700441305 r_0366_EXP_3 enolase 0.18354460093896713 prot_P00925 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 r_0366_EXP_4 enolase 0.057141304347826084 prot_P42222 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 r_0366_EXP_5 enolase 0.05715942028985507 prot_P0CX10 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 @@ -519,7 +519,7 @@ r_0373 farnesyltranstransferase 290.1726726726727 prot_Q12051 + farnesyl diphosp r_0399 fatty-acid--CoA ligase (decanoate) 799.2145593869732 prot_P39518 + ATP + coenzyme A + decanoate --> AMP + decanoyl-CoA + diphosphate 0.0 r_0399_REV fatty-acid--CoA ligase (decanoate) (reversible) 33.739859453840296 prot_P39518 + AMP + decanoyl-CoA + diphosphate --> ATP + coenzyme A + decanoate 0.0 r_0400 fatty-acid--CoA ligase (dodecanoate) 799.2145593869732 prot_P39518 + ATP + coenzyme A + laurate --> AMP + diphosphate + lauroyl-CoA 0.0 -r_0400_REV fatty-acid--CoA ligase (dodecanoate) (reversible) 33.739859453840296 prot_P39518 + AMP + diphosphate + lauroyl-CoA --> ATP + coenzyme A + laurate 7.302847455517871e-06 +r_0400_REV fatty-acid--CoA ligase (dodecanoate) (reversible) 33.739859453840296 prot_P39518 + AMP + diphosphate + lauroyl-CoA --> ATP + coenzyme A + laurate 0.0 r_0402 fatty-acid--CoA ligase (hexadecanoate) 799.2145593869732 prot_P39518 + ATP + coenzyme A + palmitate --> AMP + diphosphate + palmitoyl-CoA 0.0 r_0402_REV fatty-acid--CoA ligase (hexadecanoate) (reversible) 33.739859453840296 prot_P39518 + AMP + diphosphate + palmitoyl-CoA --> ATP + coenzyme A + palmitate 0.0 r_0410 fatty-acid--CoA ligase (octanoate) 799.2145593869732 prot_P39518 + ATP + coenzyme A + octanoate --> AMP + diphosphate + octanoyl-CoA 0.0 @@ -529,20 +529,20 @@ r_0412_REV fatty-acid--CoA ligase (tetradecanoate) (reversible) 33.7398594538402 r_0436 ferrochelatase 8.096586782861293 prot_P16622 + iron(2+) + protoporphyrin --> ferroheme b + 2.0 H+ 0.0 r_0437_EXP_1 ferrocytochrome-c:hydrogen-peroxide oxidoreductase 0.003481111111111111 prot_P00045 + 0.011209166666666666 prot_P00431 + 2.0 ferrocytochrome c + hydrogen peroxide --> 2.0 ferricytochrome c + 2.0 H2O 0.0 r_0437_EXP_2 ferrocytochrome-c:hydrogen-peroxide oxidoreductase 0.003383888888888889 prot_P00044 + 0.011209166666666666 prot_P00431 + 2.0 ferrocytochrome c + hydrogen peroxide --> 2.0 ferricytochrome c + 2.0 H2O 0.0 -r_0438_EXP_1 ferrocytochrome-c:oxygen oxidoreductase 0.0025292407050374562 prot_P00045 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003470743090051798 prot_P00425 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_2 ferrocytochrome-c:oxygen oxidoreductase 0.0025292407050374562 prot_P00045 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003459239202389243 prot_P00424 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_3 ferrocytochrome-c:oxygen oxidoreductase 0.002458602798337559 prot_P00044 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003470743090051798 prot_P00425 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_4 ferrocytochrome-c:oxygen oxidoreductase 0.002458602798337559 prot_P00044 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003459239202389243 prot_P00424 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_5 ferrocytochrome-c:oxygen oxidoreductase 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.0014052906981468086 prot_P07255 + 0.006870848273403699 prot_P19516 + 0.003495163623510905 prot_P38824 + 0.0028410566074698585 prot_P47081 + 0.007194975353860941 prot_P53239 + 0.004794901106789011 prot_Q04935 + 0.0022412398682924474 prot_Q3E731 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 15.020091007140557 -r_0439_EXP_1 ubiquinol:ferricytochrome c reductase 0.011983406387337664 prot_P00045 + 0.01650156750927913 prot_P00127 + 0.013927410950492583 prot_P00128 + 0.041744940093010934 prot_P00163 + 0.03256422793814109 prot_P07143 + 0.04802924800695788 prot_P07256 + 0.03870605839025327 prot_P07257 + 0.022342187219928544 prot_P08067 + 0.010494564722393141 prot_P08525 + 0.007148734930716276 prot_P22289 + 0.008216837782188999 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 1.5028339923117395 -r_0439_EXP_2 ubiquinol:ferricytochrome c reductase 0.01164872778571237 prot_P00044 + 0.01650156750927913 prot_P00127 + 0.013927410950492583 prot_P00128 + 0.041744940093010934 prot_P00163 + 0.03256422793814109 prot_P07143 + 0.04802924800695788 prot_P07256 + 0.03870605839025327 prot_P07257 + 0.022342187219928544 prot_P08067 + 0.010494564722393141 prot_P08525 + 0.007148734930716276 prot_P22289 + 0.008216837782188999 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 5.922752762699486 -r_0440 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 9.99999974737875e-07 +r_0438_EXP_1 ferrocytochrome-c:oxygen oxidoreductase 0.0010737358074137757 prot_P00045 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0014734307915811285 prot_P00425 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_2 ferrocytochrome-c:oxygen oxidoreductase 0.0010737358074137757 prot_P00045 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.001468547058655611 prot_P00424 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_3 ferrocytochrome-c:oxygen oxidoreductase 0.0010437479736605981 prot_P00044 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0014734307915811285 prot_P00425 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_4 ferrocytochrome-c:oxygen oxidoreductase 0.0010437479736605981 prot_P00044 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.001468547058655611 prot_P00424 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 15.155112172862445 +r_0438_EXP_5 ferrocytochrome-c:oxygen oxidoreductase 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0005965865326382158 prot_P07255 + 0.0029168737494090794 prot_P19516 + 0.001483798014107227 prot_P38824 + 0.0012061106735528025 prot_P47081 + 0.00305447506657366 prot_P53239 + 0.0020355741551656946 prot_Q04935 + 0.0009514711252258203 prot_Q3E731 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0439_EXP_1 ubiquinol:ferricytochrome c reductase 0.0023972378816698543 prot_P00045 + 0.003301079965207204 prot_P00127 + 0.002786129089253226 prot_P00128 + 0.00835092698389556 prot_P00163 + 0.006514358128013637 prot_P07143 + 0.009608080459664334 prot_P07256 + 0.007743009493634883 prot_P07257 + 0.004469475191925961 prot_P08067 + 0.0020994003950946896 prot_P08525 + 0.0014300790299524282 prot_P22289 + 0.001643749211393956 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 0.0 +r_0439_EXP_2 ubiquinol:ferricytochrome c reductase 0.002330286616222643 prot_P00044 + 0.003301079965207204 prot_P00127 + 0.002786129089253226 prot_P00128 + 0.00835092698389556 prot_P00163 + 0.006514358128013637 prot_P07143 + 0.009608080459664334 prot_P07256 + 0.007743009493634883 prot_P07257 + 0.004469475191925961 prot_P08067 + 0.0020994003950946896 prot_P08525 + 0.0014300790299524282 prot_P22289 + 0.001643749211393956 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 7.577556086431223 +r_0440 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 0.0 r_0441 FMN reductase 0.10556051587301588 prot_Q07923 + FMN + 2.0 H+ + NADH --> FMNH2 + NAD 0.0 r_0442 FMN reductase 0.10556051587301588 prot_Q07923 + FMN + 2.0 H+ + NADPH --> FMNH2 + NADP(+) 0.0 r_0443 formaldehyde dehydrogenase 8.906684027777779 prot_P32771 + formaldehyde + glutathione + NAD --> H+ + NADH + S-formylglutathione 0.0 r_0445 formate dehydrogenase 0.012874691358024692 prot_Q08911 + formate + NAD --> carbon dioxide + NADH 0.0 r_0446 formate-tetrahydrofolate ligase 0.3982132433666004 prot_P07245 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.0 -r_0446_REV formate-tetrahydrofolate ligase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.03479817931310432 +r_0446_REV formate-tetrahydrofolate ligase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.03479817931310658 r_0447 formate-tetrahydrofolate ligase 0.42978473739580797 prot_P09440 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.0 r_0447_REV formate-tetrahydrofolate ligase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.0 r_0448_EXP_1 fructose-2,6-bisphosphate 2-phosphatase 5.915698747876994 prot_Q06137 + beta-D-fructose 2,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 @@ -550,56 +550,56 @@ r_0448_EXP_2 fructose-2,6-bisphosphate 2-phosphatase 146.09722222222223 prot_P32 r_0449 fructose-bisphosphatase 0.15249083373186673 prot_P09201 + D-fructose 1,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 r_0450 fructose-bisphosphate aldolase 0.166213415970673 prot_P14540 + D-fructose 1,6-bisphosphate --> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate 1.312744149620483 r_0450_REV fructose-bisphosphate aldolase (reversible) 0.33864102564102566 prot_P14540 + dihydroxyacetone phosphate + glyceraldehyde 3-phosphate --> D-fructose 1,6-bisphosphate 0.0 -r_0451 fumarase 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 1.1200951332156535 +r_0451 fumarase 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 1.0173590915715822 r_0451_REV fumarase (reversible) 0.014265163714439076 prot_P08417 + (S)-malate --> fumarate + H2O 0.0 -r_0452 fumarase, cytoplasmic 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.05822181495555532 +r_0452 fumarase, cytoplasmic 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.15002358734501564 r_0452_REV fumarase, cytoplasmic (reversible) 0.014265163714439076 prot_P08417 + (S)-malate --> fumarate + H2O 0.0 -r_0453 dihydoorotic acid dehydrogenase 1.1372875816993464 prot_P28272 + (S)-dihydroorotate + fumarate --> orotate + succinate 0.010726833614579987 -r_0454 fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.06895229872539321 +r_0453 dihydoorotic acid dehydrogenase 1.1372875816993464 prot_P28272 + (S)-dihydroorotate + fumarate --> orotate + succinate 0.01072683361457999 +r_0454 fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.06895129872541847 r_0454_REV fumarate reductase (reversible) 0.9170995670995671 prot_P32614 + FAD + H+ + succinate --> FADH2 + fumarate 0.0 -r_0455 soluble fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.0 +r_0455 soluble fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 9.99999974737875e-07 r_0455_REV soluble fumarate reductase (reversible) 0.9170995670995671 prot_P32614 + FAD + H+ + succinate --> FADH2 + fumarate 0.0 r_0457 g-glutamyltransferase 17.374169040835707 prot_Q05902 + glutathione + L-alanine --> L-cysteinylglycine + L-gamma-glutamyl-L-alanine 0.0 r_0458 galactokinase 0.7217737917289487 prot_P04385 + ATP + D-galactose --> ADP + alpha-D-galactose 1-phosphate + H+ 0.0 r_0459 galactose-1-phosphate uridylyltransferase 0.3270447530864197 prot_P08431 + alpha-D-galactose 1-phosphate + H+ + UTP --> diphosphate + UDP-D-galactose 0.0 -r_0460 gamma-glutamylcysteine synthetase 0.00213319158216116 prot_P32477 + ATP + L-cysteine + L-glutamate --> ADP + H+ + L-gamma-glutamyl-L-cysteine + phosphate 9.999999999940612e-08 +r_0460 gamma-glutamylcysteine synthetase 0.00213319158216116 prot_P32477 + ATP + L-cysteine + L-glutamate --> ADP + H+ + L-gamma-glutamyl-L-cysteine + phosphate 1e-07 r_0461 geranylgeranyltranstransferase 0.6162073031087573 prot_standard + geranylgeranyl diphosphate + isopentenyl diphosphate --> diphosphate + pentaprenyl diphosphate 0.0 -r_0462 geranyltranstransferase 10.222979797979797 prot_P08524 + geranyl diphosphate + isopentenyl diphosphate --> farnesyl diphosphate + diphosphate 0.007449241354624062 +r_0462 geranyltranstransferase 10.222979797979797 prot_P08524 + geranyl diphosphate + isopentenyl diphosphate --> farnesyl diphosphate + diphosphate 0.007449241354620689 r_0463 glucan 1,4-alpha-glucosidase 44.78465926163774 prot_Q06625 + glycogen + H2O --> D-glucose 0.0 r_0464 glucan 1,4-alpha-glucosidase, vacuole 0.05205199864498645 prot_P08019 + glycogen + H2O --> D-glucose 0.0 r_0465 glucosamine-6-phosphate deaminase 0.1225001911377612 prot_standard + alpha-D-glucosamine 6-phosphate + H2O --> ammonium + D-fructose 6-phosphate 0.0 -r_0466 glucose 6-phosphate dehydrogenase 0.025250210703750525 prot_P11412 + D-glucose 6-phosphate + NADP(+) --> 6-O-phosphono-D-glucono-1,5-lactone + H+ + NADPH 0.019382600019956696 -r_0467 glucose-6-phosphate isomerase 0.024857664233576642 prot_P12709 + D-glucose 6-phosphate --> D-fructose 6-phosphate 1.4142870602066606 +r_0466 glucose 6-phosphate dehydrogenase 0.025250210703750525 prot_P11412 + D-glucose 6-phosphate + NADP(+) --> 6-O-phosphono-D-glucono-1,5-lactone + H+ + NADPH 0.03187331261580455 +r_0467 glucose-6-phosphate isomerase 0.024857664233576642 prot_P12709 + D-glucose 6-phosphate --> D-fructose 6-phosphate 1.4017963476108126 r_0467_REV glucose-6-phosphate isomerase (reversible) 0.024857664233576642 prot_P12709 + D-fructose 6-phosphate --> D-glucose 6-phosphate 0.0 r_0468 glutamate 5-kinase 1.0234809027777778 prot_P32264 + ATP + L-glutamate --> ADP + L-gamma-glutamyl phosphate 0.0869344136655529 r_0469 glutamate decarboxylase 34.13511276639768 prot_Q04792 + H+ + L-glutamate --> carbon dioxide + gamma-aminobutyrate 0.002263983507354179 r_0470 glutamate dehydrogenase (NAD) 1.4390277777777778 prot_P33327 + H2O + L-glutamate + NAD --> 2-oxoglutarate + ammonium + H+ + NADH 0.0 r_0471_EXP_1 glutamate dehydrogenase (NADP) 0.5307169380898228 prot_P39708 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.0 -r_0471_EXP_2 glutamate dehydrogenase (NADP) 0.5301073734280234 prot_P07262 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.592426831765378 +r_0471_EXP_2 glutamate dehydrogenase (NADP) 0.5301073734280234 prot_P07262 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.5924268317653809 r_0472 glutamate synthase (NADH2) 0.9448492063492063 prot_Q12680 + 2-oxoglutarate + H+ + L-glutamine + NADH --> 2.0 L-glutamate + NAD 0.0 r_0473 glutamate-5-semialdehyde dehydrogenase 0.2646166013940106 prot_P54885 + H+ + L-gamma-glutamyl phosphate + NADPH --> L-glutamic 5-semialdehyde + NADP(+) + phosphate 0.0869344136655529 r_0475_EXP_1 glutaminase 0.0011171565228214292 prot_P43544 + H2O + L-glutamine --> ammonium + L-glutamate 0.0 r_0475_EXP_2 glutaminase 0.0011205348411301363 prot_P53823 + H2O + L-glutamine --> ammonium + L-glutamate 0.0 -r_0476 glutamine synthetase 0.029297138047138047 prot_P32288 + ammonium + ATP + L-glutamate --> ADP + H+ + L-glutamine + phosphate 0.10449512025995478 +r_0476 glutamine synthetase 0.029297138047138047 prot_P32288 + ammonium + ATP + L-glutamate --> ADP + H+ + L-glutamine + phosphate 0.10449512025995251 r_0477 glutamine-fructose-6-phosphate transaminase 0.6263458528951487 prot_P14742 + D-fructose 6-phosphate + L-glutamine --> alpha-D-glucosamine 6-phosphate + L-glutamate 0.0023610000000000003 r_0478 glutaminyl-tRNA synthetase 15.369603878657363 prot_P13188 + ATP + L-glutamine + tRNA(Gln) --> AMP + diphosphate + Gln-tRNA(Gln) 0.0141160332291015 r_0479 glutamyl-tRNA synthetase 4.974688861932783 prot_P46655 + ATP + L-glutamate + tRNA(Glu) --> AMP + diphosphate + Glu-tRNA(Glu) 0.029648731201628798 r_0480 glutamyl-tRNA synthetase 11.407962962962962 prot_P48525 + ATP + L-glutamate + tRNA(Glu) --> AMP + diphosphate + Glu-tRNA(Glu) 0.0 -r_0481_EXP_1 glutathione oxidoreductase 0.0038209876543209877 prot_P25373 + 0.016494135802469136 prot_P41921 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.009312881881171296 +r_0481_EXP_1 glutathione oxidoreductase 0.0038209876543209877 prot_P25373 + 0.016494135802469136 prot_P41921 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0 r_0481_EXP_2 glutathione oxidoreductase 0.016494135802469136 prot_P41921 + 0.00872253086419753 prot_Q03835 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0 r_0481_EXP_3 glutathione oxidoreductase 0.00489537037037037 prot_P17695 + 0.016494135802469136 prot_P41921 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0 r_0481_EXP_4 glutathione oxidoreductase 0.008485493827160493 prot_P32642 + 0.016494135802469136 prot_P41921 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0 r_0482 glutathione oxidoreductase 0.016494135802469136 prot_P41921 + 0.0052256172839506175 prot_Q02784 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0 r_0483_EXP_1 glutathione peridoxase 0.009786866919412851 prot_P23202 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0483_EXP_2 glutathione peridoxase 0.269093567251462 prot_P38143 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 -r_0483_EXP_3 glutathione peridoxase 0.0030086516963157383 prot_P25373 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.009312881881171296 +r_0483_EXP_3 glutathione peridoxase 0.0030086516963157383 prot_P25373 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0483_EXP_4 glutathione peridoxase 0.0038546223388743073 prot_P17695 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0483_EXP_5 glutathione peridoxase 0.2725292397660819 prot_P40581 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0483_EXP_6 glutathione peridoxase 0.3697285294019552 prot_P36014 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0484 glutathione peroxidase, mitochondria 1.0350179133060056 prot_Q02784 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 -r_0485 glutathione synthetase 0.2818939393939394 prot_Q08220 + ATP + L-gamma-glutamyl-L-cysteine + L-glycine --> ADP + glutathione + H+ + phosphate 9.999999999940612e-08 +r_0485 glutathione synthetase 0.2818939393939394 prot_Q08220 + ATP + L-gamma-glutamyl-L-cysteine + L-glycine --> ADP + glutathione + H+ + phosphate 1e-07 r_0486_EXP_1 glyceraldehyde-3-phosphate dehydrogenase 1.091178266178266 prot_P00359 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 0.0 -r_0486_EXP_2 glyceraldehyde-3-phosphate dehydrogenase 0.1416581138487952 prot_P00360 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 2.503946499056416 +r_0486_EXP_2 glyceraldehyde-3-phosphate dehydrogenase 0.1416581138487952 prot_P00360 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 2.6008959602113144 r_0486_EXP_3 glyceraldehyde-3-phosphate dehydrogenase 0.5962574850299401 prot_P00358 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 0.0 r_0486_REV_EXP_1 glyceraldehyde-3-phosphate dehydrogenase (reversible) 1.091178266178266 prot_P00359 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 r_0486_REV_EXP_2 glyceraldehyde-3-phosphate dehydrogenase (reversible) 0.3424329501915709 prot_P00360 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 @@ -609,19 +609,19 @@ r_0488 glycerol kinase 0.013277445109780439 prot_P32190 + ATP + glycerol --> ADP r_0489_EXP_1 glycerol-3-phosphatase 0.6923038630027878 prot_P40106 + glycerol 3-phosphate + H2O --> glycerol + phosphate 0.0 r_0489_EXP_2 glycerol-3-phosphatase 0.6956142970927918 prot_P41277 + glycerol 3-phosphate + H2O --> glycerol + phosphate 0.0 r_0490 glycerol-3-phosphate dehydrogenase (fad) 0.6038455121788456 prot_P32191 + FAD + glycerol 3-phosphate + H+ --> dihydroxyacetone phosphate + FADH2 0.0 -r_0491_EXP_1 glycerol-3-phosphate dehydrogenase (NAD) 0.10538102261553589 prot_Q00055 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.006930530058899856 +r_0491_EXP_1 glycerol-3-phosphate dehydrogenase (NAD) 0.10538102261553589 prot_Q00055 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.006930530058899849 r_0491_EXP_2 glycerol-3-phosphate dehydrogenase (NAD) 0.1214896755162242 prot_P41911 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.0 r_0492 glycerol-3-phosphate dehydrogenase (NAD) 0.1214896755162242 prot_P41911 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.0 r_0497 glycerophosphodiester phosphodiesterase (glycerophosphocholine) 0.174260101010101 prot_Q02979 + H2O + sn-glycero-3-phosphocholine --> choline + glycerol 3-phosphate + H+ 0.0 -r_0499 glycinamide ribotide transformylase 0.1634722222222222 prot_P04161 + 10-formyl-THF + 5-phospho-ribosyl-glycineamide --> 5'-phosphoribosyl-N-formylglycineamide + H+ + THF 0.01024042638525706 +r_0499 glycinamide ribotide transformylase 0.1634722222222222 prot_P04161 + 10-formyl-THF + 5-phospho-ribosyl-glycineamide --> 5'-phosphoribosyl-N-formylglycineamide + H+ + THF 0.01024042638525704 r_0500 glycine C-acetyltransferase 0.062476381011109826 prot_standard + coenzyme A + L-2-amino-3-oxobutanoate --> acetyl-CoA + L-glycine 0.0 r_0501 glycine cleavage system 0.17131712790948955 prot_P09624 + 0.05961049407152449 prot_P39726 + 0.14105353380868527 prot_P48015 + 0.3630330791773559 prot_P49095 + L-glycine + NAD + THF --> 5,10-methylenetetrahydrofolate + ammonium + carbon dioxide + NADH 0.0 -r_0502 glycine hydroxymethyltransferase 0.0226640625 prot_P37291 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 0.08607619963280878 +r_0502 glycine hydroxymethyltransferase 0.0226640625 prot_P37291 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 0.08607619963281099 r_0502_REV glycine hydroxymethyltransferase (reversible) 63.06521739130435 prot_P37291 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF 0.0 -r_0503 glycine hydroxymethyltransferase 0.023301215277777777 prot_P37292 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 1.8993174939193698e-05 -r_0503_REV glycine hydroxymethyltransferase (reversible) 64.83816425120773 prot_P37292 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF -6.825672243772735e-09 +r_0503 glycine hydroxymethyltransferase 0.023301215277777777 prot_P37292 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 1.8993174939345e-05 +r_0503_REV glycine hydroxymethyltransferase (reversible) 64.83816425120773 prot_P37292 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF -6.825672243827108e-09 r_0504 glycine-cleavage complex (lipoamide) 0.023116760828625234 prot_P09624 + 0.00804357130628317 prot_P39726 + 0.019033127889060093 prot_P48015 + 0.048986046909775725 prot_P49095 + H+ + L-glycine + lipoamide --> carbon dioxide + S(8)-aminomethyldihydrolipoamide 0.0 -r_0505_EXP_1 glycine-cleavage complex (lipoamide) 0.016688295637127672 prot_P09624 + 0.005806760598195526 prot_P39726 + 0.013740266963292547 prot_P48015 + 0.0353636756890372 prot_P49095 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 1.1200951332156535 +r_0505_EXP_1 glycine-cleavage complex (lipoamide) 0.016688295637127672 prot_P09624 + 0.005806760598195526 prot_P39726 + 0.013740266963292547 prot_P48015 + 0.0353636756890372 prot_P49095 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 1.017339091580256 r_0505_EXP_2 glycine-cleavage complex (lipoamide) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 0.0 r_0506 glycine-cleavage complex (lipoylprotein) 0.04357695209331861 prot_P09624 + 0.015162778387145652 prot_P39726 + 0.0358789757940712 prot_P48015 + 0.09234263551254228 prot_P49095 + L-glycine + lipoylprotein --> carbon dioxide + S(8)-aminomethyldihydrolipoylprotein 0.0 r_0507 glycine-cleavage complex (lipoylprotein) 0.2838103427329358 prot_P09624 + 0.0987529674315879 prot_P39726 + 0.23367454417683617 prot_P48015 + 0.6014141369399599 prot_P49095 + H+ + S(8)-aminomethyldihydrolipoylprotein + THF --> 5,10-methylenetetrahydrofolate + ammonium + dihydrolipoylprotein 0.0 @@ -634,7 +634,7 @@ r_0510_EXP_4 glycogen (starch) synthase 18.96007470955954 prot_P27472 + 16.50835 r_0511 glycogen phosphorylase 0.568069306930693 prot_P06738 + glycogen + phosphate --> D-glucose 1-phosphate 0.0 r_0512_EXP_1 glycyl-tRNA synthetase 29.750380517503807 prot_P38088 + ATP + L-glycine + tRNA(Gly) --> AMP + diphosphate + Gly-tRNA(Gly) 0.0 r_0512_EXP_2 glycyl-tRNA synthetase 1.2407058001397624 prot_Q06817 + ATP + L-glycine + tRNA(Gly) --> AMP + diphosphate + Gly-tRNA(Gly) 0.0283748983111195 -r_0514 GMP synthase 0.0098038624019312 prot_P38625 + ATP + H2O + L-glutamine + xanthosine-5-phosphate --> AMP + diphosphate + GMP + 2.0 H+ + L-glutamate 0.0047998232011081665 +r_0514 GMP synthase 0.0098038624019312 prot_P38625 + ATP + H2O + L-glutamine + xanthosine-5-phosphate --> AMP + diphosphate + GMP + 2.0 H+ + L-glutamate 0.004799823201108194 r_0518 GPI-anchor assembly, step 2 149.73523909383033 prot_P23797 + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O --> 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate + H+ 0.0 r_0518_REV GPI-anchor assembly, step 2 (reversible) 60.09087553078704 prot_P23797 + 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate + H+ --> 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O 0.0 r_0519 GPI-anchor assembly, step 5 1.0741619906421145 prot_P25580 + 1.0571943419782979 prot_P47088 + 6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol + dolichyl D-mannosyl phosphate --> 6-O-[alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + dolichyl phosphate 0.0 @@ -650,10 +650,10 @@ r_0523_EXP_2 GPI-anchor assembly, step 9 0.03254362265000563 prot_Q07830 + 6-O-{ r_0523_REV_EXP_1 GPI-anchor assembly, step 9 (reversible) 0.007109647641562535 prot_Q06636 + 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone --> 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone 0.0 r_0523_REV_EXP_2 GPI-anchor assembly, step 9 (reversible) 0.03254362265000563 prot_Q07830 + 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone --> 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone 0.0 r_0524 GTP cyclohydrolase I 197.7849002849003 prot_P51601 + GTP + H2O --> 7,8-dihydroneopterin 3'-triphosphate + formate + H+ 6.3400002545677125e-06 -r_0525 GTP cyclohydrolase II 0.024647633744855967 prot_P38066 + GTP + 3.0 H2O --> 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + diphosphate + formate + 2.0 H+ 9.999999710998968e-05 +r_0525 GTP cyclohydrolase II 0.024647633744855967 prot_P38066 + GTP + 3.0 H2O --> 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + diphosphate + formate + 2.0 H+ 9.99999971099883e-05 r_0526 guanine deaminase 1.7229712858926343 prot_Q07729 + guanine + H+ + H2O --> 9H-xanthine + ammonium 0.0 r_0527 guanine phosphoribosyltransferase 0.09123207301173403 prot_Q04178 + guanine + PRPP --> diphosphate + GMP 0.0 -r_0528 guanylate kinase 0.014549492385786802 prot_P15454 + ATP + GMP --> ADP + GDP 0.0003463400087639259 +r_0528 guanylate kinase 0.014549492385786802 prot_P15454 + ATP + GMP --> ADP + GDP 0.00034634000876395364 r_0529 guanylate kinase (GMP:dATP) 0.014549492385786802 prot_P15454 + dATP + GMP --> dADP + GDP 0.0 r_0529_REV guanylate kinase (GMP:dATP) (reversible) 0.014549492385786802 prot_P15454 + dADP + GDP --> dATP + GMP 0.0 r_0530_EXP_1 heme O monooxygenase 0.5821949882086304 prot_P40086 + heme o + NADH + oxygen --> H2O + heme a + NAD 0.0 @@ -686,40 +686,40 @@ r_0543_EXP_2 homocitrate synthase 21.204303979830723 prot_P48570 + 2-oxoglutarat r_0544_EXP_1 homocysteine S-methyltransferase 26.83845029239766 prot_Q12525 + L-homocysteine + S-adenosyl-L-methionine --> H+ + L-methionine + S-adenosyl-L-homocysteine 0.0 r_0544_EXP_2 homocysteine S-methyltransferase 26.80482456140351 prot_Q08985 + L-homocysteine + S-adenosyl-L-methionine --> H+ + L-methionine + S-adenosyl-L-homocysteine 0.0 r_0545 homoisocitrate dehydrogenase 0.6547222222222222 prot_P40495 + homoisocitrate + NAD --> 2-oxoadipic acid + carbon dioxide + NADH 0.032939964005654 -r_0546 homoserine dehydrogenase (NADH) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADH --> L-homoserine + NAD 0.03544209944340998 +r_0546 homoserine dehydrogenase (NADH) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADH --> L-homoserine + NAD 0.03544209944341013 r_0547 homoserine dehydrogenase (NADP) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADPH --> L-homoserine + NADP(+) 0.0 r_0548 homoserine kinase 0.263562091503268 prot_P17423 + ATP + L-homoserine --> ADP + H+ + O-phospho-L-homoserine 0.023517302829840103 -r_0549 homoserine O-trans-acetylase 0.9806103801169591 prot_P08465 + acetyl-CoA + L-homoserine --> coenzyme A + O-acetyl-L-homoserine 0.011924796613569879 +r_0549 homoserine O-trans-acetylase 0.9806103801169591 prot_P08465 + acetyl-CoA + L-homoserine --> coenzyme A + O-acetyl-L-homoserine 0.011924796613570031 r_0550_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.3160087719298246 prot_Q04120 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0550_EXP_2 hydrogen peroxide reductase (thioredoxin) 0.1642543859649123 prot_P22217 + 0.3160087719298246 prot_Q04120 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0551 hydrogen peroxide reductase (thioredoxin) 0.07592592592592592 prot_P25372 + 0.15517676767676766 prot_P34227 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 -r_0552_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.2794590643274854 prot_P38013 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.00015490854661425363 +r_0552_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.2794590643274854 prot_P38013 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0552_EXP_2 hydrogen peroxide reductase (thioredoxin) 0.1642543859649123 prot_P22217 + 0.2794590643274854 prot_P38013 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 -r_0553 hydroxyacylglutathione hydrolase 0.008888605152650096 prot_Q05584 + (R)-S-lactoylglutathione + H2O --> (R)-lactate + glutathione + H+ 0.08445874855905258 +r_0553 hydroxyacylglutathione hydrolase 0.008888605152650096 prot_Q05584 + (R)-S-lactoylglutathione + H2O --> (R)-lactate + glutathione + H+ 0.0 r_0554 hydroxyacylglutathione hydrolase 0.009175746226308025 prot_Q12320 + (R)-S-lactoylglutathione + H2O --> (R)-lactate + glutathione + H+ 0.0 r_0555 hydroxybenzoate octaprenyltransferase 0.8535401716463751 prot_P32378 + 4-hydroxybenzoate + hexaprenyl diphosphate --> 3-hexaprenyl-4-hydroxybenzoic acid + diphosphate 0.0 r_0556 hydroxyethylthiazole kinase 12.64725296618268 prot_P41835 + 5-(2-hydroxyethyl)-4-methylthiazole + ATP --> 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ 0.0 r_0557 hydroxymethylbilane synthase 163.0 prot_P28789 + H2O + 4.0 porphobilinogen --> 4.0 ammonium + preuroporphyrinogen 0.0 r_0558_EXP_1 hydroxymethylglutaryl CoA reductase 1.5450320512820512 prot_P12684 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.0 -r_0558_EXP_2 hydroxymethylglutaryl CoA reductase 1.544150641025641 prot_P12683 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.022347724063872188 -r_0560 hydroxymethylglutaryl CoA synthase 3.322101449275362 prot_P54839 + acetoacetyl-CoA + acetyl-CoA + H2O --> 3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ 0.022347724063872188 -r_0561_EXP_1 hydroxymethylpyrimidine kinase (ATP) 39.57945736434109 prot_Q08224 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 +r_0558_EXP_2 hydroxymethylglutaryl CoA reductase 1.544150641025641 prot_P12683 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.022347724063862068 +r_0560 hydroxymethylglutaryl CoA synthase 3.322101449275362 prot_P54839 + acetoacetyl-CoA + acetyl-CoA + H2O --> 3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ 0.022347724063862068 +r_0561_EXP_1 hydroxymethylpyrimidine kinase (ATP) 39.57945736434109 prot_Q08224 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 1.20000004244503e-07 r_0561_EXP_2 hydroxymethylpyrimidine kinase (ATP) 39.62144702842377 prot_Q08975 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 -r_0561_EXP_3 hydroxymethylpyrimidine kinase (ATP) 340.09581877502734 prot_Q06490 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 1.20000004244503e-07 +r_0561_EXP_3 hydroxymethylpyrimidine kinase (ATP) 340.09581877502734 prot_Q06490 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 r_0562 hypoxanthine phosphoribosyltransferase (Hypoxanthine) 0.30556768558951963 prot_Q04178 + hypoxanthine + PRPP --> diphosphate + IMP 0.0 r_0563 Imidazole-glycerol-3-phosphate synthase 2.4584541062801932 prot_P33734 + 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + L-glutamine --> AICAR + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H+ + L-glutamate 0.008356708763266002 r_0564 imidazoleglycerol-phosphate dehydratase 0.004728769841269841 prot_P06633 + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate --> 3-(imidazol-4-yl)-2-oxopropyl dihydrogen phosphate + H2O 0.008356708763266002 r_0565_EXP_1 IMP dehydrogenase 6.383242999096658 prot_P38697 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0 r_0565_EXP_2 IMP dehydrogenase 6.389453477868112 prot_P50095 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0 -r_0565_EXP_3 IMP dehydrogenase 6.367886178861789 prot_P50094 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0047998232011081665 -r_0566 indole-3-glycerol-phosphate synthase 1.550264949662187 prot_P00937 + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ --> 1-C-(indol-3-yl)glycerol 3-phosphate + carbon dioxide + H2O 0.007308031687142077 +r_0565_EXP_3 IMP dehydrogenase 6.367886178861789 prot_P50094 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.004799823201108194 +r_0566 indole-3-glycerol-phosphate synthase 1.550264949662187 prot_P00937 + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ --> 1-C-(indol-3-yl)glycerol 3-phosphate + carbon dioxide + H2O 0.0073080316871415064 r_0567_EXP_1 indole-3-pyruvate decarboxylase 0.27589605734767025 prot_P26263 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 r_0567_EXP_2 indole-3-pyruvate decarboxylase 0.11780651340996169 prot_P06169 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 r_0567_EXP_3 indole-3-pyruvate decarboxylase 0.27738351254480287 prot_P16467 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 -r_0568 inorganic diphosphatase 0.03450854700854701 prot_P00817 + diphosphate + H2O --> H+ + 2.0 phosphate 2.2774357383143236 -r_0569 inorganic diphosphatase 0.03800534188034188 prot_P28239 + diphosphate + H2O --> H+ + 2.0 phosphate 0.0 +r_0568 inorganic diphosphatase 0.03450854700854701 prot_P00817 + diphosphate + H2O --> H+ + 2.0 phosphate 1.212604474756219 +r_0569 inorganic diphosphatase 0.03800534188034188 prot_P28239 + diphosphate + H2O --> H+ + 2.0 phosphate 0.1668792646874777 r_0570_EXP_1 inosine monophosphate cyclohydrolase 2.10859173126615 prot_P54113 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.0 -r_0570_EXP_2 inosine monophosphate cyclohydrolase 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.018597015148518817 +r_0570_EXP_2 inosine monophosphate cyclohydrolase 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.018597015148518796 r_0570_REV_EXP_1 inosine monophosphate cyclohydrolase (reversible) 2.10859173126615 prot_P54113 + H2O + IMP --> phosphoribosyl-formamido-carboxamide 0.0 r_0570_REV_EXP_2 inosine monophosphate cyclohydrolase (reversible) 2.1079780361757106 prot_P38009 + H2O + IMP --> phosphoribosyl-formamido-carboxamide 0.0 r_0571 inositol-1,3,4,5,6-pentakisphosphate 2-kinase 12.457614290039357 prot_Q06667 + ATP + myo-inositol 1,3,4,5,6-pentakisphosphate --> ADP + H+ + myo-inositol hexakisphosphate 0.0 @@ -790,23 +790,23 @@ r_0655 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol-P-ce r_0656 isoamyl acetate-hydrolyzing esterase 6.693496157764181 prot_P41734 + H2O + isoamyl acetate --> acetate + H+ + isoamylol 0.0 r_0657 isobutyl acetate-hydrolyzing esterase 9.93658635305908 prot_P41734 + H2O + isobutyl acetate --> acetate + H+ + isobutanol 0.0 r_0658 isocitrate dehydrogenase (NAD+) 0.5194640522875817 prot_P28241 + 0.5140392156862745 prot_P28834 + isocitrate + NAD --> 2-oxoglutarate + carbon dioxide + NADH 0.0 -r_0659 isocitrate dehydrogenase (NADP) 0.05072113289760349 prot_P41939 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 1.2695607949819017 +r_0659 isocitrate dehydrogenase (NADP) 0.05072113289760349 prot_P41939 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 1.1565199610358126 r_0659_REV isocitrate dehydrogenase (NADP) (reversible) 2.6395691609977323 prot_P41939 + 2-oxoglutarate + carbon dioxide + NADPH --> isocitrate + NADP(+) 0.0 -r_0661 isocitrate dehydrogenase (NADP+), peroxisomal 0.05213071895424837 prot_P53982 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 2.6302848062332158e-05 -r_0662 isocitrate lyase 1.3133207070707071 prot_P28240 + isocitrate --> glyoxylate + succinate 0.0 +r_0661 isocitrate dehydrogenase (NADP+), peroxisomal 0.05213071895424837 prot_P53982 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.0 +r_0662 isocitrate lyase 1.3133207070707071 prot_P28240 + isocitrate --> glyoxylate + succinate 0.10429248498530364 r_0663 isoleucine transaminase 0.010755813953488373 prot_P47176 + 2-oxoglutarate + L-isoleucine --> (S)-3-methyl-2-oxopentanoate + L-glutamate 0.0 r_0663_REV isoleucine transaminase (reversible) 0.010755813953488373 prot_P47176 + (S)-3-methyl-2-oxopentanoate + L-glutamate --> 2-oxoglutarate + L-isoleucine 0.0265490320174191 r_0664 isoleucine transaminase 0.011265116279069768 prot_P38891 + 2-oxoglutarate + L-isoleucine --> (S)-3-methyl-2-oxopentanoate + L-glutamate 0.0 r_0664_REV isoleucine transaminase (reversible) 0.011265116279069768 prot_P38891 + (S)-3-methyl-2-oxopentanoate + L-glutamate --> 2-oxoglutarate + L-isoleucine 0.0 r_0665 isoleucyl-tRNA synthetase 0.4249032614704257 prot_P09436 + ATP + L-isoleucine + tRNA(Ile) --> AMP + diphosphate + Ile-tRNA(Ile) 0.0265490320174191 r_0666 isoleucyl-tRNA synthetase 0.40006218905472635 prot_P48526 + ATP + L-isoleucine + tRNA(Ile) --> AMP + diphosphate + Ile-tRNA(Ile) 0.0 -r_0667 isopentenyl-diphosphate D-isomerase 1.1202472121456402 prot_P15496 + isopentenyl diphosphate --> prenyl diphosphate(3-) 0.007449241354624062 +r_0667 isopentenyl-diphosphate D-isomerase 1.1202472121456402 prot_P15496 + isopentenyl diphosphate --> prenyl diphosphate(3-) 0.007449241354620689 r_0667_REV isopentenyl-diphosphate D-isomerase (reversible) 1.1202472121456402 prot_P15496 + prenyl diphosphate(3-) --> isopentenyl diphosphate 0.0 r_0668 itaconate-CoA ligase (ADP-forming) 0.22156557067271354 prot_P53312 + 0.16549508692365836 prot_P53598 + ATP + coenzyme A + itaconate --> ADP + itaconyl-CoA + phosphate 0.0 r_0668_REV itaconate-CoA ligase (ADP-forming) (reversible) 0.5921843434343435 prot_P53312 + 0.44232323232323234 prot_P53598 + ADP + itaconyl-CoA + phosphate --> ATP + coenzyme A + itaconate 0.0 -r_0669 ketol-acid reductoisomerase (2-aceto-2-hydroxybutanoate) 0.6734669095324833 prot_P06168 + (S)-2-acetyl-2-hydroxybutanoate + H+ + NADPH --> (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) 0.03686112717615209 -r_0670 kynureninase 1.2721196709441296 prot_Q05979 + H2O + L-kynurenine --> anthranilate + H+ + L-alanine 0.002844050243896232 -r_0671 kynurenine 3-monooxygenase 7.174192665571977 prot_P38169 + H+ + L-kynurenine + NADPH + oxygen --> 3-hydroxy-L-kynurenine + H2O + NADP(+) 0.0006069999974000248 +r_0669 ketol-acid reductoisomerase (2-aceto-2-hydroxybutanoate) 0.6734669095324833 prot_P06168 + (S)-2-acetyl-2-hydroxybutanoate + H+ + NADPH --> (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) 0.0265490320174191 +r_0670 kynureninase 1.2721196709441296 prot_Q05979 + H2O + L-kynurenine --> anthranilate + H+ + L-alanine 0.002844050243896775 +r_0671 kynurenine 3-monooxygenase 7.174192665571977 prot_P38169 + H+ + L-kynurenine + NADPH + oxygen --> 3-hydroxy-L-kynurenine + H2O + NADP(+) 0.0006069999973989104 r_0672 L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase 11.932407407407407 prot_P07275 + 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H2O + NAD --> erythro-4-hydroxy-L-glutamic acid + H+ + NADH 0.0 r_0672_REV L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase (reversible) 11.932407407407407 prot_P07275 + erythro-4-hydroxy-L-glutamic acid + H+ + NADH --> 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H2O + NAD 0.0 r_0673 L-4-hydroxyglutamate semialdehyde dehydrogenase 11.932407407407407 prot_P07275 + H2O + L-4-hydroxyglutamic semialdehyde + NAD --> erythro-4-hydroxy-L-glutamic acid + 2.0 H+ + NADH 0.0 @@ -833,11 +833,11 @@ r_0690 L-serine dehydrogenase 0.7363131313131314 prot_Q05016 + L-serine + NADP(+ r_0691 L-sorbitol dehydrogenase (L-sorbose-producing) 0.7983182730923695 prot_P35497 + L-glucitol + NAD --> H+ + L-sorbose + NADH 0.0 r_0692 L-threonine deaminase 0.007720611346848971 prot_P25379 + L-threonine --> 2-oxobutanoate + ammonium 0.0 r_0693 L-threonine deaminase 0.01253948609146629 prot_P00927 + L-threonine --> 2-oxobutanoate + ammonium 0.0 -r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.3527200202735511 prot_P47125 + L-tryptophan + oxygen --> N-formyl-L-kynurenine 0.0034510502412962566 +r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.3527200202735511 prot_P47125 + L-tryptophan + oxygen --> N-formyl-L-kynurenine 0.003451050241295686 r_0695 L-tyrosine N-formyltransferase 52.20067092135934 prot_P21623 + 10-formyl-THF + L-tyrosine --> H+ + N-formyl-L-tyrosine + THF 0.0 r_0696 lactaldehyde dehydrogenase 0.033859544541667556 prot_Q12068 + (S)-lactaldehyde + H2O + NAD --> (S)-lactate + 2.0 H+ + NADH 0.0 -r_0697 lactoylglutathione lyase 0.005679029304029304 prot_P50107 + glutathione + methylglyoxal --> (R)-S-lactoylglutathione 0.08445874855905258 -r_0698 lanosterol synthase 24.44598824754819 prot_P38604 + (S)-2,3-epoxysqualene --> lanosterol 0.003724620677312031 +r_0697 lactoylglutathione lyase 0.005679029304029304 prot_P50107 + glutathione + methylglyoxal --> (R)-S-lactoylglutathione 0.0 +r_0698 lanosterol synthase 24.44598824754819 prot_P38604 + (S)-2,3-epoxysqualene --> lanosterol 0.0037246206773103446 r_0699 leucine transaminase 0.012875835189309577 prot_P47176 + 2-oxoglutarate + L-leucine --> 4-methyl-2-oxopentanoate + L-glutamate 0.0 r_0699_REV leucine transaminase (reversible) 0.010755813953488373 prot_P47176 + 4-methyl-2-oxopentanoate + L-glutamate --> 2-oxoglutarate + L-leucine 0.0362523293945085 r_0700 leucine transaminase 0.013485523385300667 prot_P38891 + 2-oxoglutarate + L-leucine --> 4-methyl-2-oxopentanoate + L-glutamate 0.0 @@ -858,16 +858,16 @@ r_0708 leukotriene A4 hydrolase 1.0690022111663904 prot_Q10740 + H2O + leukotrie r_0708_REV leukotriene A4 hydrolase (reversible) 4.1321047008547005 prot_Q10740 + leukotriene B4 --> H2O + leukotriene A4 0.0 r_0711 lysyl-tRNA synthetase 0.41307439824945297 prot_P15180 + ATP + L-lysine + tRNA(Lys) --> AMP + diphosphate + Lys-tRNA(Lys) 0.032939964005654 r_0712 lysyl-tRNA synthetase 0.40194505227327987 prot_P32048 + ATP + L-lysine + tRNA(Lys) --> AMP + diphosphate + Lys-tRNA(Lys) 0.0 -r_0713 malate dehydrogenase 0.05201038748832867 prot_P17505 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 1.269587097829964 +r_0713 malate dehydrogenase 0.05201038748832867 prot_P17505 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 1.2608324460124423 r_0713_REV malate dehydrogenase (reversible) 0.05201038748832867 prot_P17505 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.0 r_0714 malate dehydrogenase, cytoplasmic 0.009916009348524686 prot_P22133 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.0 -r_0714_REV malate dehydrogenase, cytoplasmic (reversible) 9.304413377192983e-05 prot_P22133 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.09604312068741344 +r_0714_REV malate dehydrogenase, cytoplasmic (reversible) 9.304413377192983e-05 prot_P22133 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.0065748742816788 r_0715 malate dehydrogenase, peroxisomal 0.009052974973220372 prot_P32419 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.0 -r_0715_REV malate dehydrogenase, peroxisomal (reversible) 8.494608918128655e-05 prot_P32419 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.00015490854661425363 +r_0715_REV malate dehydrogenase, peroxisomal (reversible) 8.494608918128655e-05 prot_P32419 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.0 r_0716_EXP_1 malate synthase 0.9084780092592593 prot_P21826 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 -r_0716_EXP_2 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 1.9000000606814286e-05 +r_0716_EXP_2 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.10431248498588974 r_0717 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 -r_0718 malic enzyme (NAD) 0.15417910447761193 prot_P36013 + (S)-malate + NAD --> carbon dioxide + NADH + pyruvate 0.004946879575879359 +r_0718 malic enzyme (NAD) 0.15417910447761193 prot_P36013 + (S)-malate + NAD --> carbon dioxide + NADH + pyruvate 0.01743759217172386 r_0719 malic enzyme (NADP) 0.15417910447761193 prot_P36013 + (S)-malate + NADP(+) --> carbon dioxide + NADPH + pyruvate 0.0 r_0721 malonyl-CoA-ACP transacylase 0.0018443121693121694 prot_P32463 + 0.0053845238095238095 prot_Q12283 + H+ + malonyl-CoA + ACP1 --> carboxyacetyl-ACP + coenzyme A 0.0 r_0721_REV malonyl-CoA-ACP transacylase (reversible) 0.0018443121693121694 prot_P32463 + 0.0053845238095238095 prot_Q12283 + carboxyacetyl-ACP + coenzyme A --> H+ + malonyl-CoA + ACP1 0.0 @@ -876,23 +876,23 @@ r_0723 mannose-6-phosphate isomerase 0.6692916666666666 prot_P29952 + D-mannose r_0723_REV mannose-6-phosphate isomerase (reversible) 0.09493498817966903 prot_P29952 + D-fructose 6-phosphate --> D-mannose 6-phosphate 0.070204 r_0724 methenyltetrahydrifikate cyclohydrolase 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.0 r_0724_REV methenyltetrahydrifikate cyclohydrolase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O 0.0 -r_0725 methenyltetrahydrofolate cyclohydrolase 1.3619742369207077 prot_P07245 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.0636356208468802 +r_0725 methenyltetrahydrofolate cyclohydrolase 1.3619742369207077 prot_P07245 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.06363562084688242 r_0725_REV methenyltetrahydrofolate cyclohydrolase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O 0.0 -r_0726_EXP_1 methionine adenosyltransferase 1.565037037037037 prot_P19358 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.016369579641541263 +r_0726_EXP_1 methionine adenosyltransferase 1.565037037037037 prot_P19358 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.016369579641541253 r_0726_EXP_2 methionine adenosyltransferase 19.92471888698304 prot_P10659 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.0 -r_0727 methionine synthase 24.2238162581693 prot_P05694 + 5-methyltetrahydrofolate + L-homocysteine --> L-methionine + THF 0.022080578792112577 +r_0727 methionine synthase 24.2238162581693 prot_P05694 + 5-methyltetrahydrofolate + L-homocysteine --> L-methionine + THF 0.022080578792112567 r_0728 methionyl-tRNA formyltransferase 95.33547008547009 prot_P32785 + 10-formyl-THF + Met-tRNA(Met) --> fMet-tRNA(fMet) + H+ + THF 0.0 r_0729 methionyl-tRNA synthetase 0.9519777777777778 prot_P00958 + ATP + L-methionine + tRNA(Met) --> AMP + diphosphate + Met-tRNA(Met) 0.00814974664727417 r_0730 methionyl-tRNA synthetase 0.7414888888888889 prot_P22438 + ATP + L-methionine + tRNA(Met) --> AMP + diphosphate + Met-tRNA(Met) 0.0 -r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 3.4304661673761956 prot_Q02046 + 5,10-methylenetetrahydrofolate + NAD --> 5,10-methenyl-THF + NADH 0.0636356208468802 +r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 3.4304661673761956 prot_Q02046 + 5,10-methylenetetrahydrofolate + NAD --> 5,10-methenyl-THF + NADH 0.06363562084688243 r_0732 methylenetetrahydrofolate dehydrogenase (NADP) 3.1493641930417993 prot_P07245 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) 0.0 r_0733 methylenetetrahydrofolate dehydrogenase (NADP) 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) 0.0 -r_0734 methylisocitrate lyase 1.3673400673400673 prot_Q12031 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> pyruvate + succinate 0.0 -r_0735 mevalonate kinase (atp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + ATP --> (R)-5-phosphomevalonic acid + ADP + H+ 0.022347724063872188 +r_0734 methylisocitrate lyase 1.3673400673400673 prot_Q12031 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> pyruvate + succinate 1.9999991326180577e-05 +r_0735 mevalonate kinase (atp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + ATP --> (R)-5-phosphomevalonic acid + ADP + H+ 0.022347724063862068 r_0736 mevalonate kinase (ctp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + CTP --> (R)-5-phosphomevalonic acid + CDP + H+ 0.0 r_0737 mevalonate kinase (gtp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + GTP --> (R)-5-phosphomevalonic acid + GDP + H+ 0.0 r_0738 mevalonate kinase (UTP) 0.4723196881091618 prot_P07277 + (R)-mevalonate + UTP --> (R)-5-phosphomevalonic acid + H+ + UDP 0.0 -r_0739 mevalonate pyrophoshate decarboxylase 2.500907029478458 prot_P32377 + (R)-5-diphosphomevalonic acid + ATP --> ADP + carbon dioxide + isopentenyl diphosphate + phosphate 0.022347724063872188 +r_0739 mevalonate pyrophoshate decarboxylase 2.500907029478458 prot_P32377 + (R)-5-diphosphomevalonic acid + ATP --> ADP + carbon dioxide + isopentenyl diphosphate + phosphate 0.022347724063862068 r_0747_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide A (C24) --> GDP + H+ + mannosylinositol phosphorylceramide A (C24) 0.0 r_0747_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide A (C24) --> GDP + H+ + mannosylinositol phosphorylceramide A (C24) 0.0 r_0748_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide A (C26) --> GDP + H+ + mannosylinositol phosphorylceramide A (C26) 0.0 @@ -913,16 +913,16 @@ r_0755_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 pro r_0755_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide D (C24) --> GDP + H+ + mannosylinositol phosphorylceramide D (C24) 0.0 r_0756_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide D (C26) --> GDP + H+ + mannosylinositol phosphorylceramide D (C26) 0.0 r_0756_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide D (C26) --> GDP + H+ + mannosylinositol phosphorylceramide D (C26) 0.0 -r_0757_EXP_1 myo-inositol 1-phosphatase 0.03326388888888889 prot_Q05533 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0008562816933829467 +r_0757_EXP_1 myo-inositol 1-phosphatase 0.03326388888888889 prot_Q05533 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0008562816933829475 r_0757_EXP_2 myo-inositol 1-phosphatase 0.0340205223880597 prot_P38710 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0 -r_0758 myo-inositol-1-phosphate synthase 1.7257523148148148 prot_P11986 + D-glucose 6-phosphate --> 1D-myo-inositol 1-phosphate 0.0008562816933829467 +r_0758 myo-inositol-1-phosphate synthase 1.7257523148148148 prot_P11986 + D-glucose 6-phosphate --> 1D-myo-inositol 1-phosphate 0.0008562816933829475 r_0759 N-acetyl-g-glutamyl-phosphate reductase 3.4224025974025976 prot_Q01217 + H+ + N-acetyl-L-gamma-glutamyl phosphate + NADPH --> 2-acetamido-5-oxopentanoate + NADP(+) + phosphate 0.0194296205196944 r_0760 N-acetylglucosamine-6-phosphate synthase 0.4886032977691562 prot_P43577 + acetyl-CoA + alpha-D-glucosamine 6-phosphate --> coenzyme A + H+ + N-acetyl-D-glucosamine 6-phosphate 0.0023610000000000003 r_0761_EXP_1 N-acteylglutamate synthase 82.8409090909091 prot_P40360 + acetyl-CoA + L-glutamate --> coenzyme A + H+ + N-acetyl-L-glutamate 0.0 r_0761_EXP_2 N-acteylglutamate synthase 0.6359516214779373 prot_Q04728 + acetyl-CoA + L-glutamate --> coenzyme A + H+ + N-acetyl-L-glutamate 0.0 r_0761_REV_EXP_1 N-acteylglutamate synthase (reversible) 23.365384615384617 prot_P40360 + coenzyme A + H+ + N-acetyl-L-glutamate --> acetyl-CoA + L-glutamate 0.0 r_0761_REV_EXP_2 N-acteylglutamate synthase (reversible) 0.6359516214779373 prot_Q04728 + coenzyme A + H+ + N-acetyl-L-glutamate --> acetyl-CoA + L-glutamate 0.0 -r_0762 N-formyl-L-kynurenine amidohydrolase 0.05174430641821946 prot_Q04066 + H2O + N-formyl-L-kynurenine --> formate + H+ + L-kynurenine 0.0034510502412962566 +r_0762 N-formyl-L-kynurenine amidohydrolase 0.05174430641821946 prot_Q04066 + H2O + N-formyl-L-kynurenine --> formate + H+ + L-kynurenine 0.003451050241295686 r_0763 N-formyltyrosine oxidase 70.69806925295306 prot_P21595 + 77.40588128458634 prot_P21623 + H+ + 2.0 N-formyl-L-tyrosine + NADPH --> N,N'-diformyldityrosine + NADP(+) 0.0 r_0764 NAD diphosphatase 4835.111111111111 prot_P53164 + H2O + NAD --> AMP + 2.0 H+ + NMN 0.0 r_0765_EXP_1 NAD kinase 18.47685185185185 prot_P32622 + ATP + NAD --> ADP + H+ + NADP(+) 0.0 @@ -935,17 +935,17 @@ r_0767_EXP_2 NAD nucleosidase nuclear 42.186868686868685 prot_P53688 + H2O + NAD r_0767_EXP_3 NAD nucleosidase nuclear 58.28484848484848 prot_P53685 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 r_0767_EXP_4 NAD nucleosidase nuclear 51.03434343434343 prot_P53687 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 r_0767_EXP_5 NAD nucleosidase nuclear 40.38282828282828 prot_P53686 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 -r_0768 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0006071199974042692 +r_0768 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0006071199974031549 r_0769 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0 r_0769_REV NAD synthase (reversible) 3.5019965277777776 prot_P38795 + AMP + diphosphate + H+ + L-glutamate + NAD --> ATP + deamido-NAD(+) + H2O + L-glutamine 0.0 r_0770_EXP_1 NADH dehydrogenase, cytosolic/mitochondrial 0.034255 prot_Q07500 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 0.8268158789990857 -r_0770_EXP_2 NADH dehydrogenase, cytosolic/mitochondrial 0.034874444444444444 prot_P40215 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 1.6185851307905448 +r_0770_EXP_2 NADH dehydrogenase, cytosolic/mitochondrial 0.034874444444444444 prot_P40215 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 1.8663066478293082 r_0771_EXP_1 NADH kinase 0.9640096618357487 prot_P32622 + ATP + NADH --> ADP + H+ + NADPH 0.0 -r_0771_EXP_2 NADH kinase 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0003270000044722221 +r_0771_EXP_2 NADH kinase 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.00032700000447230537 r_0772_EXP_1 NADH kinase mitochondrial 0.9640096618357487 prot_P32622 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0772_EXP_2 NADH kinase mitochondrial 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0772_EXP_3 NADH kinase mitochondrial 0.7979123533471358 prot_Q06892 + ATP + NADH --> ADP + H+ + NADPH 0.0 -r_0773 NADH:ubiquinone oxidoreductase 0.03180555555555555 prot_P32340 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 3.7781474961586134 +r_0773 NADH:ubiquinone oxidoreductase 0.03180555555555555 prot_P32340 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 3.6808388671986148 r_0774 NAPRtase 62.59351652704193 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 1.20000004244503e-07 r_0775 NAPRtase 54.465555555555554 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 0.0 r_0781 nicotinamidase 1.8269736842105264 prot_P53184 + H2O + nicotinamide --> ammonium + nicotinate 1.20000004244503e-07 @@ -954,9 +954,9 @@ r_0783_EXP_1 nicotinamide-nucleotide adenylyltransferase 0.15292207792207793 pro r_0783_EXP_2 nicotinamide-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + NMN --> diphosphate + NAD 0.0 r_0784_EXP_1 nicotinamide-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + NMN --> diphosphate + NAD 0.0 r_0784_EXP_2 nicotinamide-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + NMN --> diphosphate + NAD 0.0 -r_0785_EXP_1 nicotinate-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0006071199974042692 +r_0785_EXP_1 nicotinate-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0006071199974031549 r_0785_EXP_2 nicotinate-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0 -r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0006069999974000248 +r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0006069999973989104 r_0787 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0 r_0788 nucleoside diphosphatase 0.25820037372430643 prot_P40009 + ADP + H2O --> AMP + H+ + phosphate 0.0 r_0789 nucleoside diphosphatase 0.19246758812814743 prot_P40009 + GDP + H2O --> GMP + H+ + phosphate 0.0 @@ -964,12 +964,12 @@ r_0790 nucleoside diphosphatase 0.24671061667353386 prot_P40009 + H2O + UDP --> r_0791 nucleoside diphosphatase 0.004121119814331302 prot_P32621 + H2O + UDP --> H+ + phosphate + UMP 0.0 r_0792 nucleoside diphosphatase 0.00661109270913842 prot_P40009 + CDP + H2O --> CMP + H+ + phosphate 0.0 r_0793 nucleoside diphosphatase 0.24979835905993603 prot_P40009 + H2O + IDP --> H+ + IMP + phosphate 0.0 -r_0795 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + CDP --> ADP + CTP 0.1303015483470964 +r_0795 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + CDP --> ADP + CTP 0.004569617104888575 r_0796 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dADP --> ADP + dATP 0.0 r_0797 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dCDP --> ADP + dCTP 0.0 r_0798 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dGDP --> ADP + dGTP 0.0 r_0799 nucleoside diphosphate kinase 0.3585421888053467 prot_P36010 + ATP + dTDP --> ADP + dTTP 0.0 -r_0800 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + GDP --> ADP + GTP 0.30019166674818726 +r_0800 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + GDP --> ADP + GTP 0.268633976827774 r_0801 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + IDP --> ADP + ITP 0.0 r_0802 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dIDP --> ADP + dITP 0.0 r_0802_REV nucleoside diphosphate kinase (reversible) 0.3585421888053467 prot_P36010 + ADP + dITP --> ATP + dIDP 0.0 @@ -984,7 +984,7 @@ r_0807 nucleoside triphosphatase 0.00673132000048749 prot_P47119 + H2O + ITP --> r_0810 nucleoside-diphosphatase (GDP), Golgi 0.004121119814331302 prot_P32621 + GDP + H2O --> GMP + H+ + phosphate 0.0 r_0811 nucleoside-diphosphate kinase (ATP:UDP) 0.014855486327448944 prot_P36010 + ATP + UDP --> ADP + UTP 0.1552426239236641 r_0812 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + methanethiol + O-acetyl-L-homoserine --> acetate + H+ + L-methionine 0.0 -r_0813 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + hydrogen sulfide + O-acetyl-L-homoserine --> acetate + L-homocysteine 0.011924796613569879 +r_0813 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + hydrogen sulfide + O-acetyl-L-homoserine --> acetate + L-homocysteine 0.011924796613570031 r_0815_EXP_1 O-succinylhomoserine lyase (L-cysteine) 84.53345338034984 prot_Q12198 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 r_0815_EXP_2 O-succinylhomoserine lyase (L-cysteine) 0.170599173553719 prot_Q04533 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 r_0815_EXP_3 O-succinylhomoserine lyase (L-cysteine) 78.78148148148148 prot_P31373 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 @@ -994,16 +994,16 @@ r_0818 ornithine transacetylase 0.6359516214779373 prot_Q04728 + L-glutamate + N r_0819 ornithine transaminase 0.3585901027077497 prot_P07991 + 2-oxoglutarate + ornithine --> L-glutamate + L-glutamic 5-semialdehyde 0.0 r_0820_EXP_1 orotate phosphoribosyltransferase 5.27008547008547 prot_P13298 + diphosphate + orotidine 5'-(dihydrogen phosphate) --> orotate + PRPP 0.0 r_0820_EXP_2 orotate phosphoribosyltransferase 5.301495726495727 prot_P30402 + diphosphate + orotidine 5'-(dihydrogen phosphate) --> orotate + PRPP 0.0 -r_0820_REV_EXP_1 orotate phosphoribosyltransferase (reversible) 0.0019386279318367604 prot_P13298 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.010726833614579987 +r_0820_REV_EXP_1 orotate phosphoribosyltransferase (reversible) 0.0019386279318367604 prot_P13298 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.01072683361457999 r_0820_REV_EXP_2 orotate phosphoribosyltransferase (reversible) 0.001950182355530403 prot_P30402 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.0 -r_0821 orotidine-5'-phosphate decarboxylase 0.014249512670565302 prot_P03962 + H+ + orotidine 5'-(dihydrogen phosphate) --> carbon dioxide + UMP 0.010726833614579987 -r_0831_EXP_1 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.04684031538764905 prot_P09624 + 0.043736418169126635 prot_P19262 + 0.011871821465312496 prot_P19955 + 0.09922757869641279 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 1.1200951332156535 +r_0821 orotidine-5'-phosphate decarboxylase 0.014249512670565302 prot_P03962 + H+ + orotidine 5'-(dihydrogen phosphate) --> carbon dioxide + UMP 0.01072683361457999 +r_0831_EXP_1 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.04684031538764905 prot_P09624 + 0.043736418169126635 prot_P19262 + 0.011871821465312496 prot_P19955 + 0.09922757869641279 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 1.017339091580256 r_0831_EXP_2 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 0.0 -r_0832_EXP_1 oxoglutarate dehydrogenase (lipoamide) 0.023116760828625234 prot_P09624 + 0.021584916966272898 prot_P19262 + 0.005859013867488444 prot_P19955 + 0.048971066598185245 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 1.1200951332156535 +r_0832_EXP_1 oxoglutarate dehydrogenase (lipoamide) 0.023116760828625234 prot_P09624 + 0.021584916966272898 prot_P19262 + 0.005859013867488444 prot_P19955 + 0.048971066598185245 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 1.017339091580256 r_0832_EXP_2 oxoglutarate dehydrogenase (lipoamide) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 0.0 r_0841 pantetheine-phosphate adenylyltransferase 1.9636765345605238 prot_P53332 + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 0.0 -r_0842 pantothenate kinase 5.359407756813417 prot_Q04430 + (R)-pantothenate + ATP --> (R)-4'-phosphopantothenic acid + ADP + H+ 1.900000061143747e-05 -r_0843 pantothenate synthase 0.07626262626262627 prot_P40459 + (R)-pantoate + ATP + beta-alanine --> (R)-pantothenate + AMP + diphosphate + H+ 1.900000061143747e-05 +r_0842 pantothenate kinase 5.359407756813417 prot_Q04430 + (R)-pantothenate + ATP --> (R)-4'-phosphopantothenic acid + ADP + H+ 1.9000000611588824e-05 +r_0843 pantothenate synthase 0.07626262626262627 prot_P40459 + (R)-pantoate + ATP + beta-alanine --> (R)-pantothenate + AMP + diphosphate + H+ 1.9000000611588824e-05 r_0844 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + decanoyl-CoA + H2O --> coenzyme A + decanoate + H+ 0.0 r_0845 peroxisomal acyl-CoA thioesterase 1.1039815728858178 prot_P41903 + H2O + lauroyl-CoA --> coenzyme A + H+ + laurate 0.0 r_0847 peroxisomal acyl-CoA thioesterase 302.2522522522523 prot_P41903 + H2O + palmitoyl-CoA --> coenzyme A + H+ + palmitate 0.0 @@ -1011,14 +1011,14 @@ r_0848 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + r_0849 peroxisomal acyl-CoA thioesterase 588.5964912280702 prot_P41903 + H2O + stearoyl-CoA --> coenzyme A + H+ + stearate 0.0 r_0850 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + octanoyl-CoA --> coenzyme A + H+ + octanoate 0.0 r_0851 phenylalanine transaminase 1.8801204819277106 prot_P53090 + 2-oxoglutarate + L-phenylalanine --> keto-phenylpyruvate + L-glutamate 0.0 -r_0851_REV phenylalanine transaminase (reversible) 0.550322030209992 prot_P53090 + keto-phenylpyruvate + L-glutamate --> 2-oxoglutarate + L-phenylalanine 0.06030477471751655 +r_0851_REV phenylalanine transaminase (reversible) 0.550322030209992 prot_P53090 + keto-phenylpyruvate + L-glutamate --> 2-oxoglutarate + L-phenylalanine 0.060304774717517134 r_0852 phenylalanyl-tRNA synthetase 0.06206467661691542 prot_P15624 + 0.05298599594619495 prot_P15625 + ATP + L-phenylalanine + tRNA(Phe) --> AMP + diphosphate + Phe-tRNA(Phe) 0.016679595802671702 r_0853 phenylalanyl-tRNA synthetase 0.025257508752533627 prot_P08425 + ATP + L-phenylalanine + tRNA(Phe) --> AMP + diphosphate + Phe-tRNA(Phe) 0.0 r_0854 phenylpyruvate decarboxylase 0.9914444444444445 prot_Q06408 + H+ + keto-phenylpyruvate --> carbon dioxide + phenylacetaldehyde 0.0 -r_0855 phopshoribosylaminoimidazole synthetase 3.4153968253968254 prot_P07244 + 5'-phosphoribosyl-N-formylglycineamidine + ATP --> 5'-phosphoribosyl-5-aminoimidazole + ADP + H+ + phosphate 0.01024042638525706 +r_0855 phopshoribosylaminoimidazole synthetase 3.4153968253968254 prot_P07244 + 5'-phosphoribosyl-N-formylglycineamidine + ATP --> 5'-phosphoribosyl-5-aminoimidazole + ADP + H+ + phosphate 0.01024042638525704 r_0882 phosphoacetylglucosamine mutase 0.4264366394591475 prot_P38628 + N-acetyl-D-glucosamine 6-phosphate --> N-acetyl-alpha-D-glucosamine 1-phosphate 0.0023610000000000003 r_0882_REV phosphoacetylglucosamine mutase (reversible) 0.4264366394591475 prot_P38628 + N-acetyl-alpha-D-glucosamine 1-phosphate --> N-acetyl-D-glucosamine 6-phosphate 0.0 -r_0883_EXP_1 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8892063492063492 prot_P22803 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.011924916613574123 +r_0883_EXP_1 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8892063492063492 prot_P22803 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.011924916613574275 r_0883_EXP_2 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8916666666666667 prot_P22217 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.0 r_0884 phosphoenolpyruvate carboxykinase 0.27322132616487455 prot_P10963 + ATP + oxaloacetate --> ADP + carbon dioxide + phosphoenolpyruvate 0.0 r_0885 phosphoethanolamine cytidyltransferase 8.904106280193236 prot_P33412 + CTP + H+ + O-phosphoethanolamine --> CDP-ethanolamine + diphosphate 0.0 @@ -1028,49 +1028,49 @@ r_0888_EXP_2 phosphoglucomutase 0.08154005167958657 prot_P33401 + D-glucose 6-ph r_0888_REV_EXP_1 phosphoglucomutase (reversible) 0.08151033591731266 prot_P37012 + D-glucose 1-phosphate --> D-glucose 6-phosphate 0.0 r_0888_REV_EXP_2 phosphoglucomutase (reversible) 0.08154005167958657 prot_P33401 + D-glucose 1-phosphate --> D-glucose 6-phosphate 0.0 r_0889_EXP_1 phosphogluconate dehydrogenase 0.41150030525030523 prot_P53319 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.0 -r_0889_EXP_2 phosphogluconate dehydrogenase 0.40860042735042734 prot_P38720 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.019382600019956696 +r_0889_EXP_2 phosphogluconate dehydrogenase 0.40860042735042734 prot_P38720 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.03187331261580455 r_0890 phosphoglucosamine mutase 0.4264366394591475 prot_P38628 + alpha-D-glucosamine 1-phosphate --> alpha-D-glucosamine 6-phosphate 0.0 r_0890_REV phosphoglucosamine mutase (reversible) 0.4264366394591475 prot_P38628 + alpha-D-glucosamine 6-phosphate --> alpha-D-glucosamine 1-phosphate 0.0 r_0891_EXP_1 phosphoglycerate dehydrogenase 0.0036935786435786434 prot_P40054 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.0 -r_0891_EXP_2 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.1301731901671821 -r_0892 phosphoglycerate kinase 0.02315487650870546 prot_P00560 + 1,3-bisphospho-D-glycerate + ADP --> 3-phosphonato-D-glycerate(3-) + ATP 2.503946499056416 +r_0891_EXP_2 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.13017319016718404 +r_0892 phosphoglycerate kinase 0.02315487650870546 prot_P00560 + 1,3-bisphospho-D-glycerate + ADP --> 3-phosphonato-D-glycerate(3-) + ATP 2.6008959602113144 r_0892_REV phosphoglycerate kinase (reversible) 0.02315487650870546 prot_P00560 + 3-phosphonato-D-glycerate(3-) + ATP --> 1,3-bisphospho-D-glycerate + ADP 0.0 r_0893_EXP_1 phosphoglycerate mutase 1.1738045797601886 prot_Q12040 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 0.0 -r_0893_EXP_2 phosphoglycerate mutase 0.013314525462962964 prot_P00950 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 2.373773308889234 +r_0893_EXP_2 phosphoglycerate mutase 0.013314525462962964 prot_P00950 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 2.4707227700441305 r_0893_REV_EXP_1 phosphoglycerate mutase (reversible) 2.640272344101795 prot_Q12040 + 2-phospho-D-glyceric acid --> 3-phosphonato-D-glycerate(3-) 0.0 r_0893_REV_EXP_2 phosphoglycerate mutase (reversible) 0.013314525462962964 prot_P00950 + 2-phospho-D-glyceric acid --> 3-phosphonato-D-glycerate(3-) 0.0 r_0902 phosphomannomutase 1.8347853535353533 prot_P07283 + D-mannose 1-phosphate --> D-mannose 6-phosphate 0.0 r_0902_REV phosphomannomutase (reversible) 0.40001070189485594 prot_P07283 + D-mannose 6-phosphate --> D-mannose 1-phosphate 0.070204 -r_0903_EXP_1 phosphomethylpyrimidine kinase 39.57945736434109 prot_Q08224 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 1.7870618916851721e-07 +r_0903_EXP_1 phosphomethylpyrimidine kinase 39.57945736434109 prot_Q08224 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 1.20000004244503e-07 r_0903_EXP_2 phosphomethylpyrimidine kinase 39.62144702842377 prot_Q08975 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 0.0 -r_0903_EXP_3 phosphomethylpyrimidine kinase 695.1822835935426 prot_Q06490 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP -5.870618492401421e-08 -r_0904 phosphomevalonate kinase 4.122140522875817 prot_P24521 + (R)-5-phosphomevalonic acid + ATP --> (R)-5-diphosphomevalonic acid + ADP 0.022347724063872188 -r_0905 phosphopantothenate-cysteine ligase 4.010249042145594 prot_P40506 + (R)-4'-phosphopantothenic acid + CTP + L-cysteine --> CMP + diphosphate + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine 1.900000061143747e-05 -r_0906 phosphopantothenoylcysteine decarboxylase 5.98448275862069 prot_P36024 + 6.248850574712644 prot_P36076 + 7.054501915708812 prot_Q08438 + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine --> carbon dioxide + pantetheine 4'-phosphate 1.900000061143747e-05 +r_0903_EXP_3 phosphomethylpyrimidine kinase 695.1822835935426 prot_Q06490 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 0.0 +r_0904 phosphomevalonate kinase 4.122140522875817 prot_P24521 + (R)-5-phosphomevalonic acid + ATP --> (R)-5-diphosphomevalonic acid + ADP 0.022347724063862068 +r_0905 phosphopantothenate-cysteine ligase 4.010249042145594 prot_P40506 + (R)-4'-phosphopantothenic acid + CTP + L-cysteine --> CMP + diphosphate + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine 1.9000000611588824e-05 +r_0906 phosphopantothenoylcysteine decarboxylase 5.98448275862069 prot_P36024 + 6.248850574712644 prot_P36076 + 7.054501915708812 prot_Q08438 + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine --> carbon dioxide + pantetheine 4'-phosphate 1.9000000611588824e-05 r_0907_EXP_1 phosphopentomutase 0.08154005167958657 prot_P33401 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_EXP_2 phosphopentomutase 0.08151033591731266 prot_P37012 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_EXP_3 phosphopentomutase 0.10671021021021021 prot_Q03262 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_REV_EXP_1 phosphopentomutase (reversible) 0.08154005167958657 prot_P33401 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0 -r_0907_REV_EXP_2 phosphopentomutase (reversible) 0.08151033591731266 prot_P37012 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0024387474967028575 +r_0907_REV_EXP_2 phosphopentomutase (reversible) 0.08151033591731266 prot_P37012 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0024387474967028553 r_0907_REV_EXP_3 phosphopentomutase (reversible) 0.10671021021021021 prot_Q03262 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0 -r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.17755272474518155 prot_P27616 + ATP + L-aspartate + phosphoribosyl-carboxy-aminoimidazole --> 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + 2.0 H+ + phosphate 0.010240306385252815 +r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.17755272474518155 prot_P27616 + ATP + L-aspartate + phosphoribosyl-carboxy-aminoimidazole --> 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + 2.0 H+ + phosphate 0.010240306385252796 r_0909 phosphoribosyl-AMP cyclohydrolase 0.00852140040022537 prot_P00815 + 1-(5-phosphoribosyl)-5'-AMP + H2O --> 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide 0.008356708763266002 r_0910 phosphoribosyl-ATP pyrophosphatase 6.601766492974471 prot_P00815 + 5-phosphoribosyl-ATP + H2O --> 1-(5-phosphoribosyl)-5'-AMP + diphosphate + H+ 0.008356708763266002 -r_0911 phosphoribosylaminoimidazole-carboxylase 0.2248881673881674 prot_P21264 + 5'-phosphoribosyl-5-aminoimidazole + carbon dioxide --> H+ + phosphoribosyl-carboxy-aminoimidazole 0.010240306385252815 +r_0911 phosphoribosylaminoimidazole-carboxylase 0.2248881673881674 prot_P21264 + 5'-phosphoribosyl-5-aminoimidazole + carbon dioxide --> H+ + phosphoribosyl-carboxy-aminoimidazole 0.010240306385252796 r_0912_EXP_1 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.10859173126615 prot_P54113 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.0 -r_0912_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.1079780361757106 prot_P38009 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.018597015148518817 +r_0912_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.1079780361757106 prot_P38009 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.018597015148518796 r_0912_REV_EXP_1 phosphoribosylaminoimidazolecarboxamide formyltransferase (reversible) 2.10859173126615 prot_P54113 + phosphoribosyl-formamido-carboxamide + THF --> 10-formyl-THF + AICAR 0.0 r_0912_REV_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase (reversible) 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide + THF --> 10-formyl-THF + AICAR 0.0 -r_0913 phosphoribosylanthranilate isomerase 0.09719806763285024 prot_P00912 + N-(5-phospho-beta-D-ribosyl)anthranilate --> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 0.007308031687142077 -r_0914 phosphoribosylglycinamidine synthetase 3.4153968253968254 prot_P07244 + 5-phosphoribosylamine + ATP + L-glycine --> 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate 0.01024042638525706 -r_0915 phosphoribosylpyrophosphate amidotransferase 0.28336830535571544 prot_P04046 + H2O + L-glutamine + PRPP --> 5-phosphoribosylamine + diphosphate + L-glutamate 0.01024042638525706 -r_0916_EXP_1 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11565202927478377 prot_P38620 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.03723912044764935 +r_0913 phosphoribosylanthranilate isomerase 0.09719806763285024 prot_P00912 + N-(5-phospho-beta-D-ribosyl)anthranilate --> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 0.0073080316871415064 +r_0914 phosphoribosylglycinamidine synthetase 3.4153968253968254 prot_P07244 + 5-phosphoribosylamine + ATP + L-glycine --> 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate 0.01024042638525704 +r_0915 phosphoribosylpyrophosphate amidotransferase 0.28336830535571544 prot_P04046 + H2O + L-glutamine + PRPP --> 5-phosphoribosylamine + diphosphate + L-glutamate 0.01024042638525704 +r_0916_EXP_1 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11565202927478377 prot_P38620 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.03723912044764769 r_0916_EXP_2 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11684630738522954 prot_P38689 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_3 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11882900864936793 prot_P38063 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_4 phosphoribosylpyrophosphate synthetase 0.11565202927478377 prot_P38620 + 0.17799401197604792 prot_Q12265 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_5 phosphoribosylpyrophosphate synthetase 0.11882900864936793 prot_P38063 + 0.17799401197604792 prot_Q12265 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 -r_0917 phosphoserine phosphatase (L-serine) 0.006309392061384094 prot_P42941 + 3-phospho-serine + H2O --> L-serine + phosphate 0.1301731901671821 -r_0918 phosphoserine transaminase 4.103165485515034 prot_P33330 + 3-phospho-hydroxypyruvate + L-glutamate --> 2-oxoglutarate + 3-phospho-serine 0.13017319016718207 +r_0917 phosphoserine phosphatase (L-serine) 0.006309392061384094 prot_P42941 + 3-phospho-serine + H2O --> L-serine + phosphate 0.13017319016718404 +r_0918 phosphoserine transaminase 4.103165485515034 prot_P33330 + 3-phospho-hydroxypyruvate + L-glutamate --> 2-oxoglutarate + 3-phospho-serine 0.13017319016718404 r_0919 phytoceramidase 13.387690165065315 prot_P38298 + lignoceric acid + phytosphingosine --> ceramide-2 (C24) + H2O 0.0 r_0920 phytoceramidase 107.0999354737445 prot_P21595 + cerotic acid + phytosphingosine --> ceramide-2 (C26) + H2O 0.0 r_0921 Phytosphingosine phosphate lyase 82.78535353535354 prot_Q05567 + phytosphingosine 1-phosphate --> 2-hydroxyhexadecanal + O-phosphoethanolamine 0.0 @@ -1079,8 +1079,8 @@ r_0929 polyamine oxidase 0.4117236467236467 prot_P50264 + H2O + N(1)-acetylsperm r_0935 porphobilinogen synthase 1.9935529153386848 prot_P05373 + 2.0 5-aminolevulinate --> H+ + 2.0 H2O + porphobilinogen 0.0 r_0936 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + N(1)-acetylspermine + oxygen --> 3-aminopropanal + hydrogen peroxide + N(1)-acetylspermidine 0.0 r_0937 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + oxygen + spermine --> 3-aminopropanal + hydrogen peroxide + spermidine 0.0024387474967028553 -r_0938 prephenate dehydratase 0.012934651669576752 prot_P32452 + H+ + prephenate --> carbon dioxide + H2O + keto-phenylpyruvate 0.016679595802671705 -r_0939 prephenate dehydrogenase (NADP) 0.537843261512463 prot_P20049 + NAD + prephenate --> 3-(4-hydroxyphenyl)pyruvate + carbon dioxide + NADH 0.024793278675129028 +r_0938 prephenate dehydratase 0.012934651669576752 prot_P32452 + H+ + prephenate --> carbon dioxide + H2O + keto-phenylpyruvate 0.016679595802671702 +r_0939 prephenate dehydrogenase (NADP) 0.537843261512463 prot_P20049 + NAD + prephenate --> 3-(4-hydroxyphenyl)pyruvate + carbon dioxide + NADH 0.012302566079285501 r_0940 proline oxidase (NAD) 0.44171641791044775 prot_P09368 + FAD + L-proline --> 1-pyrroline-5-carboxylate + FADH2 0.06895229872539321 r_0941 prolyl-tRNA synthetase 3.83859126984127 prot_P38708 + ATP + L-proline + tRNA(Pro) --> AMP + diphosphate + Pro-tRNA(Pro) 0.0179821149401597 r_0942 protoporphyrinogen oxidase 34.59572043825653 prot_P40012 + 3.0 oxygen + 2.0 protoporphyrinogen --> 6.0 H2O + 2.0 protoporphyrin 0.0 @@ -1094,25 +1094,25 @@ r_0951_REV inosine phosphorylase (reversible) 0.07382983377077865 prot_Q05788 + r_0953 pyridoxal oxidase 10.677777777777777 prot_P38075 + ammonium + 2.0 H2O + 0.5 oxygen + pyridoxal --> 2.0 hydrogen peroxide + pyridoxamine 0.0 r_0954 pyridoxamine 5'-phosphate oxidase 72.56742179072278 prot_P38075 + H2O + oxygen + pyridoxamine 5'-phosphate --> ammonium + hydrogen peroxide + pyridoxal 5'-phosphate 0.0 r_0955 pyridoxine 5'-phosphate oxidase 10.677777777777777 prot_P38075 + oxygen + pyridoxine 5'-phosphate --> hydrogen peroxide + pyridoxal 5'-phosphate 0.0 -r_0956 pyridoxine oxidase 10.677777777777777 prot_P38075 + oxygen + pyridoxine --> hydrogen peroxide + pyridoxal 0.006874134384468441 +r_0956 pyridoxine oxidase 10.677777777777777 prot_P38075 + oxygen + pyridoxine --> hydrogen peroxide + pyridoxal 0.0 r_0957 pyrroline-5-carboxylate reductase 0.0020925 prot_P32263 + 1-pyrroline-5-carboxylate + 2.0 H+ + NADPH --> L-proline + NADP(+) 0.0869344136655529 r_0958_EXP_1 pyruvate carboxylase 0.602625 prot_P32327 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.0 -r_0958_EXP_2 pyruvate carboxylase 0.6023101851851852 prot_P11154 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.22901688253957464 +r_0958_EXP_2 pyruvate carboxylase 0.6023101851851852 prot_P11154 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.1393937275872258 r_0959_EXP_1 pyruvate decarboxylase 0.27589605734767025 prot_P26263 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.0 -r_0959_EXP_2 pyruvate decarboxylase 0.08176022088979121 prot_P06169 + H+ + pyruvate --> acetaldehyde + carbon dioxide 1.7866578571085567 +r_0959_EXP_2 pyruvate decarboxylase 0.08176022088979121 prot_P06169 + H+ + pyruvate --> acetaldehyde + carbon dioxide 1.0614969761113306 r_0959_EXP_3 pyruvate decarboxylase 0.27738351254480287 prot_P16467 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.0 r_0960_EXP_1 pyruvate decarboxylase (acetoin-forming) 0.27589605734767025 prot_P26263 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 r_0960_EXP_2 pyruvate decarboxylase (acetoin-forming) 0.11780651340996169 prot_P06169 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 r_0960_EXP_3 pyruvate decarboxylase (acetoin-forming) 0.27738351254480287 prot_P16467 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 -r_0961 pyruvate dehydrogenase 0.23664570803230708 prot_P09624 + 1.1352071189426114 prot_P12695 + 0.4061052415234663 prot_P16387 + 0.19875435304131667 prot_P16451 + 0.35099452655160257 prot_P32473 + coenzyme A + NAD + pyruvate --> acetyl-CoA + carbon dioxide + NADH 0.1329434706423851 -r_0962_EXP_1 pyruvate kinase 0.06530771072796934 prot_P00549 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 2.281886917046632 +r_0961 pyruvate dehydrogenase 0.23664570803230708 prot_P09624 + 1.1352071189426114 prot_P12695 + 0.4061052415234663 prot_P16387 + 0.19875435304131667 prot_P16451 + 0.35099452655160257 prot_P32473 + coenzyme A + NAD + pyruvate --> acetyl-CoA + carbon dioxide + NADH 1.0152406605930202 +r_0962_EXP_1 pyruvate kinase 0.06530771072796934 prot_P00549 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 2.4038178033932174 r_0962_EXP_2 pyruvate kinase 0.06608596743295019 prot_P52489 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 0.0 r_0963 quinone oxidoreductase 0.2834173315594083 prot_O13525 + 0.266570923780901 prot_P27680 + 0.191209663200305 prot_P41735 + 0.2544937516539746 prot_P49017 + 0.39274288726487816 prot_P53318 + 0.21981040253855474 prot_Q05779 + 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + NADH + oxygen --> 2-hexaprenyl-5-hydroxy-6-methoxy-3-methyl-1,4-benzoquinone + H2O + NAD 0.0 r_0964 reduced glutathione via ABC system 161.4141633681904 prot_P39109 + ATP + glutathione + H2O --> ADP + glutathione + H+ + phosphate 0.0 r_0965 riboflavin kinase 68.15833333333333 prot_Q03778 + ATP + riboflavin --> ADP + FMN + H+ 0.0 -r_0966 riboflavin kinase 68.15833333333333 prot_Q03778 + ATP + riboflavin --> ADP + FMN + H+ 0.0 -r_0967 riboflavin synthase 1.4057441999969114 prot_P50861 + 2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil --> 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ + 2.0 H2O + phosphate 0.00019999999421997937 -r_0968 riboflavin synthase 54.506866416978774 prot_P38145 + 2.0 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ --> 5-amino-6-(D-ribitylamino)uracil + riboflavin 9.999999710998968e-05 +r_0966 riboflavin kinase 68.15833333333333 prot_Q03778 + ATP + riboflavin --> ADP + FMN + H+ 9.999999747364874e-07 +r_0967 riboflavin synthase 1.4057441999969114 prot_P50861 + 2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil --> 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ + 2.0 H2O + phosphate 0.0001999999942199766 +r_0968 riboflavin synthase 54.506866416978774 prot_P38145 + 2.0 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ --> 5-amino-6-(D-ribitylamino)uracil + riboflavin 9.99999971099883e-05 r_0969 ribokinase 0.214529735759604 prot_P25332 + ATP + D-ribose --> ADP + H+ + ribose-5-phosphate 0.0 r_0970 ribonucleoside-triphosphate reductase (ATP) 1.6386358549460274 prot_P22803 + ATP + H+ + TRX1 --> dATP + H2O + TRX1 disulphide 0.0 r_0971 ribonucleoside-triphosphate reductase (CTP) 3.573997388312029 prot_P22803 + CTP + H+ + TRX1 --> dCTP + H2O + TRX1 disulphide 0.0 @@ -1146,9 +1146,9 @@ r_0982 ribose-5-phosphate isomerase 0.5468480156600358 prot_Q12189 + D-ribulose r_0982_REV ribose-5-phosphate isomerase (reversible) 0.817650462962963 prot_Q12189 + ribose-5-phosphate --> D-ribulose 5-phosphate 0.0 r_0983 ribosylnicotinamide kinase 4.5245098039215685 prot_P53915 + ATP + nicotinamide riboside --> ADP + H+ + NMN 0.0 r_0984 ribulose 5-phosphate 3-epimerase 0.06355115026921195 prot_P46969 + D-ribulose 5-phosphate --> D-xylulose 5-phosphate 0.0 -r_0984_REV ribulose 5-phosphate 3-epimerase (reversible) 0.06355115026921195 prot_P46969 + D-xylulose 5-phosphate --> D-ribulose 5-phosphate 0.02897791058617734 +r_0984_REV ribulose 5-phosphate 3-epimerase (reversible) 0.06355115026921195 prot_P46969 + D-xylulose 5-phosphate --> D-ribulose 5-phosphate 0.016487197990329494 r_0985 S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase 0.55303275478674 prot_O13525 + 0.5201603286342985 prot_P27680 + 0.37310776373372107 prot_P41735 + 0.49659412068703435 prot_P49017 + 0.7663599105669565 prot_P53318 + 0.42891643844723004 prot_Q05779 + 3-hexaprenyl-4,5-dihydroxybenzoic acid + S-adenosyl-L-methionine --> 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid + H+ + S-adenosyl-L-homocysteine 0.0 -r_0986 S-adenosyl-methionine delta-24-sterol-c-methyltransferase 1096.7424242424245 prot_P25087 + S-adenosyl-L-methionine + zymosterol --> fecosterol + H+ + S-adenosyl-L-homocysteine 0.0004991467112704911 +r_0986 S-adenosyl-methionine delta-24-sterol-c-methyltransferase 1096.7424242424245 prot_P25087 + S-adenosyl-L-methionine + zymosterol --> fecosterol + H+ + S-adenosyl-L-homocysteine 0.0 r_0987 S-formylglutathione hydralase 0.3307407407407407 prot_P40363 + H2O + S-formylglutathione --> formate + glutathione + H+ 0.0 r_0988 saccharopine dehydrogenase (NAD, L-lysine forming) 0.6126625295508275 prot_P38998 + H2O + L-saccharopine + NAD --> 2-oxoglutarate + H+ + L-lysine + NADH 0.032939964005654 r_0989 saccharopine dehydrogenase (NADP, L-glutamate forming) 0.2203315572298126 prot_P38999 + H+ + L-allysine + L-glutamate + NADPH --> H2O + L-saccharopine + NADP(+) 0.032939964005654 @@ -1158,8 +1158,8 @@ r_0992 serine O-acetyltransferase 17.435821109618253 prot_P07347 + 62.4747269081 r_0993 serine palmitotransferase 11.220598845598845 prot_P25045 + 12.829184704184705 prot_P32368 + 11.383658008658008 prot_P40970 + 4.553571428571429 prot_P53224 + 4.483225108225108 prot_Q06144 + 1.727813852813853 prot_Q3E790 + H+ + L-serine + palmitoyl-CoA --> 3-ketosphinganine + carbon dioxide + coenzyme A 0.0 r_0995_EXP_1 seryl-tRNA synthetase 3.797008547008547 prot_P07284 + ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + Ser-tRNA(Ser) 0.026520149099018314 r_0995_EXP_2 seryl-tRNA synthetase 3.589031339031339 prot_P38705 + ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + Ser-tRNA(Ser) 0.001252416799286889 -r_0996 shikimate dehydrogenase 0.12478934590117109 prot_P08566 + 3-dehydroshikimate + H+ + NADPH --> NADP(+) + shikimate 0.04594319592130103 -r_0997 shikimate kinase 0.1645527306967985 prot_P08566 + ATP + shikimate --> 3-phosphoshikimic acid + ADP + H+ 0.04594319592130103 +r_0996 shikimate dehydrogenase 0.12478934590117109 prot_P08566 + 3-dehydroshikimate + H+ + NADPH --> NADP(+) + shikimate 0.0334524833254565 +r_0997 shikimate kinase 0.1645527306967985 prot_P08566 + ATP + shikimate --> 3-phosphoshikimic acid + ADP + H+ 0.0334524833254565 r_0998 sirohydrochlorin dehydrogenase 147.7685185185185 prot_P15807 + NAD + precorrin-2 --> 2.0 H+ + NADH + sirohydrochlorin 0.0 r_0999 sirohydrochlorin ferrochetalase 147.7685185185185 prot_P15807 + iron(2+) + sirohydrochlorin --> 2.0 H+ + siroheme 0.0 r_1000 fumarate reductase (FMN) 0.9170995670995671 prot_P32614 + FMNH2 + fumarate --> FMN + H+ + succinate 0.0 @@ -1180,23 +1180,23 @@ r_1008_REV spontaneous cis-aconitate(3-) to trans-aconitate (reversible) 1.13290 r_1009 spontaneous cis-aconitate(3-) to trans-aconitate 1.1329040404040405 prot_standard + cis-aconitate --> trans-aconitate 0.0 r_1009_REV spontaneous cis-aconitate(3-) to trans-aconitate (reversible) 1.1329040404040405 prot_standard + trans-aconitate --> cis-aconitate 0.0 r_1010 squalene epoxidase (NAD) 201.483918128655 prot_P32476 + H+ + NADH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NAD 0.0 -r_1011 squalene epoxidase (NADP) 161.16753104520652 prot_P32476 + H+ + NADPH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NADP(+) 0.003724620677312031 -r_1012 squalene synthase 8.707070707070708 prot_P29704 + 2.0 farnesyl diphosphate + H+ + NADPH --> 2.0 diphosphate + NADP(+) + squalene 0.003724620677312031 +r_1011 squalene epoxidase (NADP) 161.16753104520652 prot_P32476 + H+ + NADPH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NADP(+) 0.0037246206773103446 +r_1012 squalene synthase 8.707070707070708 prot_P29704 + 2.0 farnesyl diphosphate + H+ + NADPH --> 2.0 diphosphate + NADP(+) + squalene 0.0037246206773103446 r_1021_EXP_1 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07412606837606837 prot_P47052 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.0 r_1021_EXP_2 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07503098290598291 prot_Q00711 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.0 -r_1021_EXP_3 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.07412606837606837 prot_P47052 + 0.019905982905982906 prot_Q06236 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 1.2020382490629808 +r_1021_EXP_3 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.07412606837606837 prot_P47052 + 0.019905982905982906 prot_Q06236 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 1.2035946924042131 r_1021_REV_EXP_1 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.022498888888888888 prot_P37298 + 0.07709111111111111 prot_P47052 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 r_1021_REV_EXP_2 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.022498888888888888 prot_P37298 + 0.07803222222222223 prot_Q00711 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 r_1021_REV_EXP_3 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.07709111111111111 prot_P47052 + 0.020702222222222223 prot_Q06236 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 -r_1022 succinate-CoA ligase (ADP-forming) 0.06481619679380873 prot_P53312 + 0.048413488114980655 prot_P53598 + ADP + phosphate + succinyl-CoA --> ATP + coenzyme A + succinate 0.9228143270788077 +r_1022 succinate-CoA ligase (ADP-forming) 0.06481619679380873 prot_P53312 + 0.048413488114980655 prot_P53598 + ADP + phosphate + succinyl-CoA --> ATP + coenzyme A + succinate 0.8200582854434102 r_1023 succinate-semialdehyde dehydrogenase (NADP) 0.6660398230088496 prot_P38067 + H2O + NADP(+) + succinic semialdehyde --> 2.0 H+ + NADPH + succinate 0.002263983507354179 r_1024 sucrose hydrolyzing enzyme 0.004910835762876579 prot_P00724 + H2O + sucrose --> D-fructose + D-glucose 0.0 -r_1025 sulfate adenylyltransferase 0.6571607468123861 prot_P08536 + ATP + H+ + sulphate --> 5'-adenylyl sulfate + diphosphate 0.011924916613574123 +r_1025 sulfate adenylyltransferase 0.6571607468123861 prot_P08536 + ATP + H+ + sulphate --> 5'-adenylyl sulfate + diphosphate 0.011924916613574275 r_1026 sulfate adenylyltransferase (ADP) 0.10559317129629629 prot_P16550 + 5'-adenylyl sulfate + phosphate --> ADP + H+ + sulphate 0.0 -r_1027 sulfite reductase (NADPH2) 0.4089351851851852 prot_P39692 + 0.574141737891738 prot_P47169 + 4.0 H+ + 3.0 NADPH + sulphite --> 3.0 H2O + hydrogen sulfide + 3.0 NADP(+) 0.011924916613574123 +r_1027 sulfite reductase (NADPH2) 0.4089351851851852 prot_P39692 + 0.574141737891738 prot_P47169 + 4.0 H+ + 3.0 NADPH + sulphite --> 3.0 H2O + hydrogen sulfide + 3.0 NADP(+) 0.011924916613574275 r_1028 taurcholate via ABC system 571.7858889359086 prot_P32386 + ATP + H2O + taurocholate --> ADP + H+ + phosphate + taurocholate 0.0 r_1029 taurine dioxygenase 0.6971220085126848 prot_Q12358 + 2-oxoglutarate + oxygen + taurine --> aminoacetaldehyde + carbon dioxide + H+ + succinate + sulphite 0.0 -r_1030 tetrahydrofolate aminomethyltransferase 0.12487609595740357 prot_P09624 + 0.0434511474046933 prot_P39726 + 0.10281642494222884 prot_P48015 + 0.2646212564047546 prot_P49095 + 5,10-methenyl-THF + H2O --> 5-formyltetrahydrofolic acid + H+ 0.0 +r_1030 tetrahydrofolate aminomethyltransferase 0.12487609595740357 prot_P09624 + 0.0434511474046933 prot_P39726 + 0.10281642494222884 prot_P48015 + 0.2646212564047546 prot_P49095 + 5,10-methenyl-THF + H2O --> 5-formyltetrahydrofolic acid + H+ 2.558567263896446 r_1031_EXP_1 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) 6.686527777777778 prot_P36001 + ATP + L-glutamate + THF --> 5,6,7,8-tetrahydrofolyl-L-glutamic acid + ADP + H+ + phosphate 0.0 r_1031_EXP_2 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) 8.632083333333334 prot_Q08645 + ATP + L-glutamate + THF --> 5,6,7,8-tetrahydrofolyl-L-glutamic acid + ADP + H+ + phosphate 0.0 r_1031_REV_EXP_1 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) (reversible) 6.686527777777778 prot_P36001 + 5,6,7,8-tetrahydrofolyl-L-glutamic acid + ADP + H+ + phosphate --> ATP + L-glutamate + THF 0.0 @@ -1210,7 +1210,7 @@ r_1037_EXP_1 thioredoxin 0.16380116959064328 prot_P22803 + 0.3526315789473684 pr r_1037_EXP_2 thioredoxin 0.1642543859649123 prot_P22217 + 0.3526315789473684 prot_P40553 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_1038_EXP_1 thioredoxin reductase (NADPH) 0.09346012679346014 prot_P22803 + 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1038_EXP_2 thioredoxin reductase (NADPH) 0.09371871871871873 prot_P22217 + 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 -r_1038_EXP_3 thioredoxin reductase (NADPH) 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.01327982517061919 +r_1038_EXP_3 thioredoxin reductase (NADPH) 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.013124916624005088 r_1039_EXP_1 thioredoxin reductase (NADPH) 0.12038705372038706 prot_P25372 + 0.3093677010343677 prot_P38816 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1039_EXP_2 thioredoxin reductase (NADPH) 0.004454320987654321 prot_P25372 + 0.016494135802469136 prot_P41921 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1040 threonine aldolase 0.2765826873385013 prot_P37303 + L-threonine --> acetaldehyde + L-glycine 0.0 @@ -1221,22 +1221,22 @@ r_1045 thymidylate synthase 0.20281828703703703 prot_P06785 + 5,10-methylenetetr r_1046 trans-aconitate 3-methyltransferase 147.17240726195595 prot_P32643 + S-adenosyl-L-methionine + trans-aconitate --> (2E)-3-(methoxycarbonyl)pent-2-enedioic acid + S-adenosyl-L-homocysteine 0.0 r_1047 trans-pentaprenyltranstransferase 1.43565817535086 prot_P18900 + isopentenyl diphosphate + pentaprenyl diphosphate --> diphosphate + hexaprenyl diphosphate 0.0 r_1048_EXP_1 transaldolase 0.796025641025641 prot_P53228 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.0 -r_1048_EXP_2 transaldolase 0.13717037037037036 prot_P15019 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.008482642667561845 +r_1048_EXP_2 transaldolase 0.13717037037037036 prot_P15019 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.008482642667563503 r_1048_REV_EXP_1 transaldolase (reversible) 0.4518922852983988 prot_P53228 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 r_1048_REV_EXP_2 transaldolase (reversible) 0.13717037037037036 prot_P15019 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 r_1049_EXP_1 transketolase 1 0.30204911433172305 prot_P33315 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 -r_1049_EXP_2 transketolase 1 0.2971256038647343 prot_P23254 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.008482642667561845 +r_1049_EXP_2 transketolase 1 0.2971256038647343 prot_P23254 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.008482642667563503 r_1049_REV_EXP_1 transketolase 1 (reversible) 0.30204911433172305 prot_P33315 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0 r_1049_REV_EXP_2 transketolase 1 (reversible) 0.2971256038647343 prot_P23254 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0 r_1050_EXP_1 transketolase 2 0.30204911433172305 prot_P33315 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.0 r_1050_EXP_2 transketolase 2 0.2971256038647343 prot_P23254 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.0 r_1050_REV_EXP_1 transketolase 2 (reversible) 0.30204911433172305 prot_P33315 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.0 -r_1050_REV_EXP_2 transketolase 2 (reversible) 0.2971256038647343 prot_P23254 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.03746055325373918 +r_1050_REV_EXP_2 transketolase 2 (reversible) 0.2971256038647343 prot_P23254 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.024969840657892997 r_1051_EXP_1 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5532575757575757 prot_P38427 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.0 r_1051_EXP_2 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5004419191919192 prot_P38426 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.013655 -r_1054 triose-phosphate isomerase 0.0008592271925605259 prot_P00942 + dihydroxyacetone phosphate --> glyceraldehyde 3-phosphate 1.2213548710025306 +r_1054 triose-phosphate isomerase 0.0008592271925605259 prot_P00942 + dihydroxyacetone phosphate --> glyceraldehyde 3-phosphate 1.3058136195615833 r_1054_REV triose-phosphate isomerase (reversible) 0.0008592271925605259 prot_P00942 + glyceraldehyde 3-phosphate --> dihydroxyacetone phosphate 0.0 -r_1055 tryptophan synthase (indoleglycerol phosphate) 0.43168564547057753 prot_P00931 + 1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> glyceraldehyde 3-phosphate + H2O + L-tryptophan 0.007308031687142077 +r_1055 tryptophan synthase (indoleglycerol phosphate) 0.43168564547057753 prot_P00931 + 1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> glyceraldehyde 3-phosphate + H2O + L-tryptophan 0.0073080316871415064 r_1056 tryptophan transaminase 1.2484 prot_P53090 + 2-oxoglutarate + L-tryptophan --> indole-3-pyruvate + L-glutamate 0.0 r_1057 tryptophanyl-tRNA synthetase 0.5595238095238095 prot_Q12109 + ATP + L-tryptophan + tRNA(Trp) --> AMP + diphosphate + Trp-tRNA(Trp) 0.0038569814458458205 r_1058 tryptophanyl-tRNA synthetase 0.4876984126984127 prot_P04803 + ATP + L-tryptophan + tRNA(Trp) --> AMP + diphosphate + Trp-tRNA(Trp) 0.0 @@ -1252,7 +1252,7 @@ r_1070 UDPglucose 4-epimerase 0.532373366013072 prot_P04397 + UDP-D-glucose --> r_1070_REV UDPglucose 4-epimerase (reversible) 0.532373366013072 prot_P04397 + UDP-D-galactose --> UDP-D-glucose 0.0 r_1071 UDPglucose--hexose-1-phosphate uridylyltransferase 0.3270447530864197 prot_P08431 + alpha-D-galactose 1-phosphate + UDP-D-glucose --> D-glucose 1-phosphate + UDP-D-galactose 0.0 r_1071_REV UDPglucose--hexose-1-phosphate uridylyltransferase (reversible) 0.3270447530864197 prot_P08431 + D-glucose 1-phosphate + UDP-D-galactose --> alpha-D-galactose 1-phosphate + UDP-D-glucose 0.0 -r_1072 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.004927623923664108 +r_1072 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.0049276239236641095 r_1073 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.0 r_1074 uracil phosphoribosyltransferase 1.1199453551912568 prot_P18562 + PRPP + uracil --> diphosphate + UMP 0.0 r_1075 urea carboxylase 0.26596036263967954 prot_P32528 + ATP + bicarbonate + urea --> ADP + H+ + phosphate + urea-1-carboxylic acid 0.0 @@ -1313,23 +1313,23 @@ r_1103_REV 5-formyltetrahydrofolic acid transport (reversible) 5-formyltetrahydr r_1104 8-Amino-7-oxononanoate transport 1.86456462002342 prot_P53744 + 8-amino-7-oxononanoate + H+ --> 8-amino-7-oxononanoate + H+ 0.0 r_1106 acetate transport 0.7536246695645853 prot_P25613 + acetate --> acetate 0.01 r_1106_REV acetate transport (reversible) 0.7536246695645853 prot_P25613 + acetate --> acetate 0.0 -r_1107 acetic ester transport ethyl acetate --> ethyl acetate 0.16778232905888193 +r_1107 acetic ester transport ethyl acetate --> ethyl acetate 0.12158141345131043 r_1108_EXP_1 adenine transport 13.568751070237582 prot_P17064 + adenine + H+ --> adenine + H+ 0.0 r_1108_EXP_2 adenine transport 96.43325000488205 prot_P40039 + adenine + H+ --> adenine + H+ 0.0 r_1108_EXP_3 adenine transport 170.37838815188596 prot_Q12119 + adenine + H+ --> adenine + H+ 0.0 r_1109 adenosine transport 38.061322453849215 prot_P31381 + adenosine + H+ --> adenosine + H+ 0.0 r_1110_EXP_1 ADP/ATP transporter 0.06555300613384876 prot_P18239 + ADP + ATP --> ADP + ATP 0.0 -r_1110_EXP_2 ADP/ATP transporter 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 7.453821534742222 +r_1110_EXP_2 ADP/ATP transporter 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 7.120700448235984 r_1110_EXP_3 ADP/ATP transporter 0.045422922213833025 prot_P04710 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_1 ADP/ATP transporter (reversible) 0.06555300613384876 prot_P18239 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_2 ADP/ATP transporter (reversible) 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_3 ADP/ATP transporter (reversible) 0.045422922213833025 prot_P04710 + ADP + ATP --> ADP + ATP 0.0 r_1111 ADP/ATP transporter 1.0879458482506026 prot_Q06497 + ADP + ATP + H+ --> ADP + ATP + H+ 0.0 -r_1112 AKG transporter, mitochonrial 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 1.069205057718473 +r_1112 AKG transporter, mitochonrial 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 0.9664490160830757 r_1112_REV AKG transporter, mitochonrial (reversible) 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 0.0 r_1113 allantoate uniport 1.2976708311906466 prot_P15365 + allantoate --> allantoate 0.0 r_1114 allantoin uniport 10.243314336688835 prot_Q04895 + allantoin --> allantoin 0.0 -r_1115_EXP_1 ammonia transport 0.565835007774522 prot_Q12359 + ammonium --> ammonium 0.6976144059917709 +r_1115_EXP_1 ammonia transport 0.565835007774522 prot_Q12359 + ammonium --> ammonium 0.6976144059917715 r_1115_EXP_2 ammonia transport 1.0213597006592061 prot_P40260 + ammonium --> ammonium 0.0 r_1115_EXP_3 ammonia transport 1.006265993411724 prot_P41948 + ammonium --> ammonium 0.0 r_1115_EXP_4 ammonia transport 1.0117117879117519 prot_P53390 + ammonium --> ammonium 0.0 @@ -1340,7 +1340,7 @@ r_1115_REV_EXP_4 ammonia transport (reversible) 1.3558080808080808 prot_P53390 + r_1116 AMP/ATP transporter 0.6269423034333512 prot_Q06497 + AMP + ATP + H+ --> AMP + ATP + H+ 0.0 r_1118 aspartate-glutamate transporter 3.465624071522008 prot_Q12482 + L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 r_1119 biotin uptake 12.492477484389962 prot_P53241 + biotin + H+ --> biotin + H+ 0.0 -r_1120 carnithine-acetylcarnithine carrier 1.094665810308139 prot_Q12289 + (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.0001739085472208489 +r_1120 carnithine-acetylcarnithine carrier 1.094665810308139 prot_Q12289 + (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.0 r_1121 ceramide-2' (sphinganine:n-C24:0OH) transport ceramide-2' (C24) --> ceramide-2' (C24) 0.0 r_1121_REV ceramide-2' (sphinganine:n-C24:0OH) transport (reversible) ceramide-2' (C24) --> ceramide-2' (C24) 0.0 r_1122 ceramide-2' (sphinganine:n-C26:0OH) transport ceramide-2' (C26) --> ceramide-2' (C26) 0.0 @@ -1351,14 +1351,14 @@ r_1124 ceramide-3 (Phytosphingosine:n-C26:0OH) transport ceramide-3 (C26) --> ce r_1124_REV ceramide-3 (Phytosphingosine:n-C26:0OH) transport (reversible) ceramide-3 (C26) --> ceramide-3 (C26) 0.0 r_1125 choline transport 49.19344031664132 prot_P19807 + choline + H+ --> choline + H+ 0.0 r_1126 citrate transport 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.0 -r_1126_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.15443884419018983 +r_1126_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.2609109466125842 r_1127 citrate transport 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.0 -r_1127_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.04594319592130103 +r_1127_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.0334524833254565 r_1128 citrate transport 0.3417805406736961 prot_P38152 + citrate + isocitrate --> citrate + isocitrate 0.0 r_1128_REV citrate transport (reversible) 0.3417805406736961 prot_P38152 + citrate + isocitrate --> citrate + isocitrate 0.0 -r_1129 coenzyme A transport 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.02232872406326644 +r_1129 coenzyme A transport 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.02230872406266448 r_1130 CTP transport 0.2701553629071786 prot_P38127 + CMP + CTP + H+ --> CMP + CTP + H+ 0.0 -r_1131 CTP/CMP antiport 0.2701553629071786 prot_P38127 + CMP + CTP + 2.0 H+ --> CMP + CTP + 2.0 H+ 0.06499172648942508 +r_1131 CTP/CMP antiport 0.2701553629071786 prot_P38127 + CMP + CTP + 2.0 H+ --> CMP + CTP + 2.0 H+ 0.0 r_1132 cytidine transport 19.950758151174124 prot_P31381 + cytidine + H+ --> cytidine + H+ 0.0 r_1133_EXP_1 cytosine transport 1.2026606480417619 prot_P17064 + cytosine + H+ --> cytosine + H+ 0.0 r_1133_EXP_2 cytosine transport 10.825248896185835 prot_P40039 + cytosine + H+ --> cytosine + H+ 0.0 @@ -1385,9 +1385,9 @@ r_1135_EXP_3 D-galactose transport 7.895711187219881 prot_P13181 + D-galactose + r_1135_EXP_4 D-galactose transport 9.049001302171312 prot_P42833 + D-galactose + H+ --> D-galactose + H+ 0.0 r_1135_EXP_5 D-galactose transport 0.8760873219329858 prot_P54862 + D-galactose + H+ --> D-galactose + H+ 0.0 r_1136 D-lactate transport 1398.5378967792055 prot_P36035 + (R)-lactate + H+ --> (R)-lactate + H+ 0.0 -r_1137 D-lactate transport (R)-lactate + H+ --> (R)-lactate + H+ 0.30032128698786975 +r_1137 D-lactate transport (R)-lactate + H+ --> (R)-lactate + H+ 1.1597956691926015 r_1138 D-lactate/pyruvate antiport (R)-lactate + pyruvate --> (R)-lactate + pyruvate 0.0 -r_1138_REV D-lactate/pyruvate antiport (reversible) (R)-lactate + pyruvate --> (R)-lactate + pyruvate 0.2863509398376345 +r_1138_REV D-lactate/pyruvate antiport (reversible) (R)-lactate + pyruvate --> (R)-lactate + pyruvate 1.1597956691926015 r_1139_EXP_1 D-mannose transport 21.752276959457756 prot_P54854 + D-mannose + H+ --> D-mannose + H+ 0.0 r_1139_EXP_10 D-mannose transport 5.737789186505133 prot_P40885 + D-mannose + H+ --> D-mannose + H+ 0.0 r_1139_EXP_11 D-mannose transport 24.62776935429521 prot_P47185 + D-mannose + H+ --> D-mannose + H+ 0.0 @@ -1415,7 +1415,7 @@ r_1148_REV_EXP_1 ergosterol transport (reversible) 220.04126278706457 prot_P4055 r_1148_REV_EXP_2 ergosterol transport (reversible) 300.989150017774 prot_Q08409 + ergosterol --> ergosterol 0.0 r_1149 ethanolamine transport 19.35463221575592 prot_P19807 + ethanolamine --> ethanolamine 0.0 r_1149_REV ethanolamine transport (reversible) 19.35463221575592 prot_P19807 + ethanolamine --> ethanolamine 0.0 -r_1151 fadH2 transport 2.2694626476781234 prot_P40464 + FADH2 --> FADH2 0.0 +r_1151 fadH2 transport 2.2694626476781234 prot_P40464 + FADH2 --> FADH2 9.99999974737875e-07 r_1161_EXP_1 fecosterol transport 202.39396969322675 prot_P40550 + fecosterol --> fecosterol 0.0 r_1161_EXP_2 fecosterol transport 242.95341636695454 prot_Q08409 + fecosterol --> fecosterol 0.0 r_1161_REV_EXP_1 fecosterol transport (reversible) 202.39396969322675 prot_P40550 + fecosterol --> fecosterol 0.0 @@ -1467,12 +1467,12 @@ r_1173_EXP_3 glycine transport 12.596301854889402 prot_P38967 + H+ + L-glycine - r_1173_EXP_4 glycine transport 14.445193920799005 prot_P15380 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_EXP_5 glycine transport 7.968919773312661 prot_P53388 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_1 glycine transport (reversible) 25.955237884466197 prot_P25376 + H+ + L-glycine --> H+ + L-glycine 0.0 -r_1173_REV_EXP_2 glycine transport (reversible) 4.0449974975144505 prot_P19145 + H+ + L-glycine --> H+ + L-glycine 0.047479654937039414 +r_1173_REV_EXP_2 glycine transport (reversible) 4.0449974975144505 prot_P19145 + H+ + L-glycine --> H+ + L-glycine 0.04747965493704179 r_1173_REV_EXP_3 glycine transport (reversible) 12.596301854889402 prot_P38967 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_4 glycine transport (reversible) 14.445193920799005 prot_P15380 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_5 glycine transport (reversible) 9.41498101418254 prot_P53388 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1174 glycogen vacuolar 'transport' via autophagy glycogen --> glycogen 0.0 -r_1175 GTP/GDP translocase 0.5104257838599212 prot_P38988 + GDP + GTP + H+ --> GDP + GTP + H+ 0.21608413480341204 +r_1175 GTP/GDP translocase 0.5104257838599212 prot_P38988 + GDP + GTP + H+ --> GDP + GTP + H+ 0.18452644488299888 r_1176_EXP_1 guanine transport 1.98390967747123 prot_P17064 + guanine + H+ --> guanine + H+ 0.0 r_1176_EXP_2 guanine transport 26.93240415537185 prot_P40039 + guanine + H+ --> guanine + H+ 0.0 r_1176_EXP_3 guanine transport 75.93503728388835 prot_Q12119 + guanine + H+ --> guanine + H+ 0.0 @@ -1637,13 +1637,13 @@ r_1241 pantothenate transport 34.938176452130854 prot_P25621 + (R)-pantothenate r_1242 pentaprenyl diphosphate transport pentaprenyl diphosphate --> pentaprenyl diphosphate 0.0 r_1242_REV pentaprenyl diphosphate transport (reversible) pentaprenyl diphosphate --> pentaprenyl diphosphate 0.0 r_1243 phenethyl acetate transport phenethyl acetate --> phenethyl acetate 0.0 -r_1244_EXP_1 phosphate transport 1.5821717171717171 prot_P38361 + H+ + phosphate --> H+ + phosphate 0.027912664680937338 +r_1244_EXP_1 phosphate transport 1.5821717171717171 prot_P38361 + H+ + phosphate --> H+ + phosphate 0.027912664680954827 r_1244_EXP_2 phosphate transport 2.5893939393939394 prot_P25360 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_3 phosphate transport 2.4668939393939393 prot_P39535 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_4 phosphate transport 1.6258080808080808 prot_P25297 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_5 phosphate transport 2.5123737373737374 prot_P27514 + H+ + phosphate --> H+ + phosphate 0.0 -r_1245_EXP_1 phosphate transport 0.8466666666666667 prot_P40035 + H+ + phosphate --> H+ + phosphate 0.0 -r_1245_EXP_2 phosphate transport 0.8285858585858585 prot_P23641 + H+ + phosphate --> H+ + phosphate 0.897245674887089 +r_1245_EXP_1 phosphate transport 0.8466666666666667 prot_P40035 + H+ + phosphate --> H+ + phosphate 0.02044328373360127 +r_1245_EXP_2 phosphate transport 0.8285858585858585 prot_P23641 + H+ + phosphate --> H+ + phosphate 0.9417941176429128 r_1249_EXP_1 potassium transport 1.7714141414141413 prot_Q04121 + H+ + potassium --> H+ + potassium 0.000362999993376434 r_1249_EXP_2 potassium transport 3.562449494949495 prot_P12685 + H+ + potassium --> H+ + potassium 0.0 r_1250 putrescine excretion 14.581286007528888 prot_P36029 + putrescine --> putrescine 0.0 @@ -1687,8 +1687,8 @@ r_1263_REV_EXP_2 spermine transport (reversible) 14.118248201928578 prot_Q07824 r_1263_REV_EXP_3 spermine transport (reversible) 4.735615277275769 prot_Q12256 + H+ + spermine --> H+ + spermine 0.0 r_1263_REV_EXP_4 spermine transport (reversible) 5.6450672243090425 prot_Q06451 + H+ + spermine --> H+ + spermine 0.0 r_1264 succinate transport 0.32879485380079526 prot_Q06143 + phosphate + succinate --> phosphate + succinate 0.0 -r_1265 succinate-fumarate transport 0.5875590154537462 prot_P33303 + fumarate + succinate --> fumarate + succinate 0.012990817121934166 -r_1266_EXP_1 sulfate uniport 2.4230050505050507 prot_P38359 + sulphate --> sulphate 0.013924916568870642 +r_1265 succinate-fumarate transport 0.5875590154537462 prot_P33303 + fumarate + succinate --> fumarate + succinate 0.11728430210721255 +r_1266_EXP_1 sulfate uniport 2.4230050505050507 prot_P38359 + sulphate --> sulphate 0.013924916568870795 r_1266_EXP_2 sulfate uniport 2.516439393939394 prot_Q12325 + sulphate --> sulphate 0.0 r_1267 sulfite transport 296.1052693373152 prot_P41930 + sulphite --> sulphite 0.0 r_1268 taurine transport taurine --> taurine 0.0 @@ -1705,11 +1705,11 @@ r_1275 UTP transport 0.3655624733979681 prot_P38127 + FMN + H+ + UMP + UTP --> F r_1276 UTP/UMP antiport 0.3655624733979681 prot_P38127 + 2.0 H+ + UMP + UTP --> 2.0 H+ + UMP + UTP 0.0 r_1277_EXP_1 water diffusion 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_1277_EXP_2 water diffusion 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_1277_REV_EXP_1 water diffusion (reversible) 0.4050171892049932 prot_P0CD90 + H2O --> H2O 5.932272301617025 +r_1277_REV_EXP_1 water diffusion (reversible) 0.4050171892049932 prot_P0CD90 + H2O --> H2O 5.9328944757129065 r_1277_REV_EXP_2 water diffusion (reversible) 0.77827345573678 prot_P0CD91 + H2O --> H2O 0.0 r_1278_EXP_1 zymosterol transport 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 0.0 r_1278_EXP_2 zymosterol transport 254.30179320863886 prot_Q08409 + zymosterol --> zymosterol 0.0 -r_1278_REV_EXP_1 zymosterol transport (reversible) 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 3.692933003312214e-06 +r_1278_REV_EXP_1 zymosterol transport (reversible) 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 3.6929330016225934e-06 r_1278_REV_EXP_2 zymosterol transport (reversible) 254.30179320863886 prot_Q08409 + zymosterol --> zymosterol 0.0 r_1449 inositol-P-ceramide B' (C24) [Golgi] SLIME rxn inositol-P-ceramide B' (C24) --> 0.910263542 inositol-P-ceramide backbone + 0.28448264 C18:0 chain + 0.36864392 C24:0 chain 0.0 r_1450 inositol-P-ceramide B' (C26) [Golgi] SLIME rxn inositol-P-ceramide B' (C26) --> 0.938317302 inositol-P-ceramide backbone + 0.28448264 C18:0 chain + 0.39669768 C26:0 chain 0.0 @@ -1763,15 +1763,15 @@ r_1564 2'-deoxyguanosine exchange 2'-deoxyguanosine --> 0.0 r_1565 2'-deoxyinosine exchange 2'-deoxyinosine --> 0.0 r_1566 2'-deoxyuridine exchange 2'-deoxyuridine --> 0.0 r_1567 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.0 -r_1567_REV 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport (reversible) 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.04594319592130103 +r_1567_REV 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport (reversible) 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.0334524833254565 r_1568 2-dehydropantoate transport 2-dehydropantoate --> 2-dehydropantoate 0.0 -r_1568_REV 2-dehydropantoate transport (reversible) 2-dehydropantoate --> 2-dehydropantoate 1.900000061143747e-05 +r_1568_REV 2-dehydropantoate transport (reversible) 2-dehydropantoate --> 2-dehydropantoate 1.9000000611588824e-05 r_1572 2-isopropylmalate exchange 2-isopropylmalate --> 0.0 r_1573 2-isopropylmalate transport 2-isopropylmalate --> 2-isopropylmalate 0.0 r_1573_REV 2-isopropylmalate transport (reversible) 2-isopropylmalate --> 2-isopropylmalate 0.0 r_1574 2-isopropylmalate transport 0.6302029418767878 prot_P32332 + 2-isopropylmalate --> 2-isopropylmalate 0.0 r_1574_REV 2-isopropylmalate transport (reversible) 0.6302029418767878 prot_P32332 + 2-isopropylmalate --> 2-isopropylmalate 0.0362523293945085 -r_1575 2-methyl-1-butanol transport 2-methylbutanol --> 2-methylbutanol 0.010312095158732992 +r_1575 2-methyl-1-butanol transport 2-methylbutanol --> 2-methylbutanol 0.0 r_1575_REV 2-methyl-1-butanol transport (reversible) 2-methylbutanol --> 2-methylbutanol 0.0 r_1576 2-methyl-1-butanol transport 2-methylbutanol --> 2-methylbutanol 0.0 r_1576_REV 2-methyl-1-butanol transport (reversible) 2-methylbutanol --> 2-methylbutanol 0.0 @@ -1780,13 +1780,13 @@ r_1578 2-methylbutanal transport 2-methylbutanal --> 2-methylbutanal 0.0 r_1578_REV 2-methylbutanal transport (reversible) 2-methylbutanal --> 2-methylbutanal 0.0 r_1579 2-methylbutanal transport 2-methylbutanal --> 2-methylbutanal 0.0 r_1579_REV 2-methylbutanal transport (reversible) 2-methylbutanal --> 2-methylbutanal 0.0 -r_1580 2-methylbutanol exchange 2-methylbutanol --> 0.010312095158732992 +r_1580 2-methylbutanol exchange 2-methylbutanol --> 0.0 r_1581 2-methylbutyl acetate exchange 2-methylbutyl acetate --> 0.0 r_1582 2-methylpropanal transport isobutyraldehyde --> isobutyraldehyde 0.0 r_1582_REV 2-methylpropanal transport (reversible) isobutyraldehyde --> isobutyraldehyde 0.0 r_1583 2-methylpropanal transport isobutyraldehyde --> isobutyraldehyde 0.0 r_1583_REV 2-methylpropanal transport (reversible) isobutyraldehyde --> isobutyraldehyde 0.0 -r_1585_EXP_1 2-oxobutanoate transporter 3.025147963735379 prot_P53943 + 2-oxobutanoate --> 2-oxobutanoate 0.03686112717615209 +r_1585_EXP_1 2-oxobutanoate transporter 3.025147963735379 prot_P53943 + 2-oxobutanoate --> 2-oxobutanoate 0.0265490320174191 r_1585_EXP_2 2-oxobutanoate transporter 39.053720824554496 prot_P36035 + 2-oxobutanoate --> 2-oxobutanoate 0.0 r_1585_REV_EXP_1 2-oxobutanoate transporter (reversible) 3.025147963735379 prot_P53943 + 2-oxobutanoate --> 2-oxobutanoate 0.0 r_1585_REV_EXP_2 2-oxobutanoate transporter (reversible) 39.053720824554496 prot_P36035 + 2-oxobutanoate --> 2-oxobutanoate 0.0 @@ -1803,7 +1803,7 @@ r_1591_REV 2-phenylethanol transport (reversible) 2-phenylethanol --> 2-phenylet r_1595 3-carboxy-4-methyl-2-oxopentanoate transport (2S)-2-isopropyl-3-oxosuccinate --> (2S)-2-isopropyl-3-oxosuccinate 0.0 r_1595_REV 3-carboxy-4-methyl-2-oxopentanoate transport (reversible) (2S)-2-isopropyl-3-oxosuccinate --> (2S)-2-isopropyl-3-oxosuccinate 0.0 r_1596 3-methyl-2-oxopentanoate transport (S)-3-methyl-2-oxopentanoate --> (S)-3-methyl-2-oxopentanoate 0.0 -r_1596_REV 3-methyl-2-oxopentanoate transport (reversible) (S)-3-methyl-2-oxopentanoate --> (S)-3-methyl-2-oxopentanoate 0.03686112717615209 +r_1596_REV 3-methyl-2-oxopentanoate transport (reversible) (S)-3-methyl-2-oxopentanoate --> (S)-3-methyl-2-oxopentanoate 0.0265490320174191 r_1597 3-methyl-oxopentanoate trasport (S)-3-methyl-2-oxopentanoate --> (S)-3-methyl-2-oxopentanoate 0.0 r_1597_REV 3-methyl-oxopentanoate trasport (reversible) (S)-3-methyl-2-oxopentanoate --> (S)-3-methyl-2-oxopentanoate 0.0 r_1598 3-methylbutanal exchange 3-methylbutanal --> 0.0 @@ -1844,7 +1844,7 @@ r_1620 5'-nucleotidase (XMP) 0.5934259259259259 prot_standard + H2O + xanthosine r_1621 5-aminolevulinate exchange 5-aminolevulinate --> 0.0 r_1622 5-aminolevulinate transport 5-aminolevulinate --> 5-aminolevulinate 0.0 r_1622_REV 5-aminolevulinate transport (reversible) 5-aminolevulinate --> 5-aminolevulinate 0.0 -r_1623 5-formethyltetrahydrofolate cyclo-ligase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP --> 5,10-methenyl-THF + ADP + phosphate 0.0 +r_1623 5-formethyltetrahydrofolate cyclo-ligase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP --> 5,10-methenyl-THF + ADP + phosphate 2.558567263896446 r_1624 5-formyltetrahydrofolate:10-formyltetrahydrofolate isomerase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP + H2O --> 10-formyl-THF + ADP + H+ + phosphate 0.0 r_1625 5-formyltetrahydrofolic acid exchange 5-formyltetrahydrofolic acid --> 0.0 r_1627 7,8-diaminononanoate exchange 7,8-diaminononanoate --> 0.0 @@ -1852,17 +1852,17 @@ r_1628 7,8-diaminononanoate transport 7,8-diaminononanoate --> 7,8-diaminononano r_1628_REV 7,8-diaminononanoate transport (reversible) 7,8-diaminononanoate --> 7,8-diaminononanoate 0.0 r_1629 8-amino-7-oxononanoate exchange 8-amino-7-oxononanoate --> 0.0 r_1630 9H-xanthine exchange 9H-xanthine --> 0.0 -r_1631 acetaldehyde exchange acetaldehyde --> 0.0 +r_1631 acetaldehyde exchange acetaldehyde --> 0.17123751545051236 r_1632 acetaldehyde transport acetaldehyde --> acetaldehyde 0.0 -r_1632_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 1.272705184232137 +r_1632_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.3818072510198447 r_1633 acetaldehyde transport acetaldehyde --> acetaldehyde 0.0 -r_1633_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.0 +r_1633_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.17123751545051236 r_1634 acetate exchange acetate --> 0.01 r_1635 acetate transport acetate --> acetate 0.0 r_1635_REV acetate transport (reversible) acetate --> acetate 0.0 r_1637 acetyl-CoA transport acetyl-CoA --> acetyl-CoA 0.0 r_1637_REV acetyl-CoA transport (reversible) acetyl-CoA --> acetyl-CoA 0.0 -r_1638 acetylcarnitine transport O-acetylcarnitine --> O-acetylcarnitine 0.0001739085472208489 +r_1638 acetylcarnitine transport O-acetylcarnitine --> O-acetylcarnitine 0.0 r_1639 adenine exchange adenine --> 0.0 r_1640 adenine transport adenine --> adenine 0.0 r_1640_REV adenine transport (reversible) adenine --> adenine 0.0 @@ -1882,12 +1882,12 @@ r_1650 trehalose exchange trehalose --> 0.0 r_1651 alpha-D-glucosamine 6-phosphate exchange alpha-D-glucosamine 6-phosphate --> 0.0 r_1652 alpha-ketoglutarate/malate transporter (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 r_1652_REV alpha-ketoglutarate/malate transporter (reversible) (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 -r_1654 ammonium exchange ammonium <=> -0.6976144059917709 +r_1654 ammonium exchange ammonium <=> -0.6976144059917715 r_1656 AMP transport AMP --> AMP 0.0 r_1656_REV AMP transport (reversible) AMP --> AMP 0.0 r_1657 arginine transport 25.141189431578304 prot_P38279 + H+ + L-arginine --> H+ + L-arginine 0.0 r_1658 asparagine transport 5.8602645666708675 prot_P48813 + L-asparagine --> L-asparagine 0.0 -r_1659 aspartate-glutamate transporter L-aspartate + L-glutamate --> L-aspartate + L-glutamate 2.630284806233215e-05 +r_1659 aspartate-glutamate transporter L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 r_1659_REV aspartate-glutamate transporter (reversible) L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 r_1660 ATP diffusion ATP --> ATP 0.0 r_1660_REV ATP diffusion (reversible) ATP --> ATP 0.0 @@ -1898,7 +1898,7 @@ r_1664 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + r_1664_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1665 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + H2O --> bicarbonate + H+ 0.0 r_1665_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 -r_1667 bicarbonate formation 7.346040189125295e-06 prot_P53615 + carbon dioxide + H2O --> bicarbonate + H+ 0.37772506350591856 +r_1667 bicarbonate formation 7.346040189125295e-06 prot_P53615 + carbon dioxide + H2O --> bicarbonate + H+ 0.28794700000695544 r_1667_REV bicarbonate formation (reversible) 7.346040189125295e-06 prot_P53615 + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1668 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + H2O --> bicarbonate + H+ 0.0 r_1668_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 @@ -1906,7 +1906,7 @@ r_1669 bicarbonate transport bicarbonate --> bicarbonate 0.0 r_1669_REV bicarbonate transport (reversible) bicarbonate --> bicarbonate 0.0 r_1671 biotin exchange biotin --> 0.0 r_1672 carbon dioxide exchange carbon dioxide --> 4.39533734616 -r_1673 carnitine transport (R)-carnitine --> (R)-carnitine 0.0001739085472208489 +r_1673 carnitine transport (R)-carnitine --> (R)-carnitine 0.0 r_1674 carnitine-acetylcarnitine carrier (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.0 r_1675 CDP transport CDP --> CDP 0.0 r_1675_REV CDP transport (reversible) CDP --> CDP 0.0 @@ -1922,10 +1922,10 @@ r_1680 ceramide transport ceramide-2 (C26) --> ceramide-2 (C26) 0.0 r_1680_REV ceramide transport (reversible) ceramide-2 (C26) --> ceramide-2 (C26) 0.0 r_1681 ceramide transport ceramide-4 (C26) --> ceramide-4 (C26) 0.0 r_1681_REV ceramide transport (reversible) ceramide-4 (C26) --> ceramide-4 (C26) 0.0 -r_1682 cholestenol delta-isomerase, lumped reaction 2.489610027058053 prot_standard + oxygen + S-adenosyl-L-methionine + zymosterol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + 2.0 H2O + S-adenosyl-L-homocysteine 0.003221781033038228 +r_1682 cholestenol delta-isomerase, lumped reaction 2.489610027058053 prot_standard + oxygen + S-adenosyl-L-methionine + zymosterol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + 2.0 H2O + S-adenosyl-L-homocysteine 0.003720927744308722 r_1683 choline exchange choline --> 0.0 r_1684_EXP_1 choline transport 49.19344031664132 prot_P19807 + choline --> choline 0.0 -r_1684_EXP_2 choline transport 4.890140948879145 prot_Q12412 + choline --> choline 0.003399616352539276 +r_1684_EXP_2 choline transport 4.890140948879145 prot_Q12412 + choline --> choline 0.0033996163525392663 r_1684_REV_EXP_1 choline transport (reversible) 49.19344031664132 prot_P19807 + choline --> choline 0.0 r_1684_REV_EXP_2 choline transport (reversible) 4.890140948879145 prot_Q12412 + choline --> choline 0.0 r_1685 chorismate pyruvate lyase 0.6162073031087573 prot_standard + chorismate --> 4-hydroxybenzoate + pyruvate 0.0 @@ -1933,28 +1933,28 @@ r_1686 citrate transport citrate --> citrate 0.0 r_1686_REV citrate transport (reversible) citrate --> citrate 0.0 r_1687 citrate exchange citrate --> 0.0 r_1688 citrate/isocitrate antiport citrate + isocitrate --> citrate + isocitrate 0.0 -r_1688_REV citrate/isocitrate antiport (reversible) citrate + isocitrate --> citrate + isocitrate 2.6302848062332158e-05 -r_1689 citrate/malate antiport (S)-malate + citrate --> (S)-malate + citrate 0.0 -r_1689_REV citrate/malate antiport (reversible) (S)-malate + citrate --> (S)-malate + citrate 2.6302848062332158e-05 +r_1688_REV citrate/isocitrate antiport (reversible) citrate + isocitrate --> citrate + isocitrate 0.0 +r_1689 citrate/malate antiport (S)-malate + citrate --> (S)-malate + citrate 1000.0 +r_1689_REV citrate/malate antiport (reversible) (S)-malate + citrate --> (S)-malate + citrate 1000.0 r_1690 CMP nucleosidase 0.9660422049956934 prot_standard + CMP + H2O --> cytosine + ribose-5-phosphate 0.0 r_1691 CO2 transport carbon dioxide --> carbon dioxide 0.0 r_1691_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1694 CO2 transport carbon dioxide --> carbon dioxide 0.0 r_1694_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1695 CO2 transport carbon dioxide --> carbon dioxide 0.0 -r_1695_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 2.6302848062332158e-05 +r_1695_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1696 CO2 transport carbon dioxide --> carbon dioxide 0.0 -r_1696_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 1.39551835898833 +r_1696_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 2.177238124740679 r_1697 CO2 transport carbon dioxide --> carbon dioxide 4.39533734616 r_1697_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1698 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1698_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 r_1699 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1699_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 -r_1700 coenzyme A transport coenzyme A --> coenzyme A 1.9000000606595314e-05 +r_1700 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1700_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 r_1702 cytidine exchange cytidine --> 0.0 -r_1703 cytidylate kinase (CMP) 0.015537262872628726 prot_P15700 + ATP + CMP --> ADP + CDP 0.07016134359952889 +r_1703 cytidylate kinase (CMP) 0.015537262872628726 prot_P15700 + ATP + CMP --> ADP + CDP 0.005169617110103981 r_1704 cytidylate kinase (dCMP) 0.0872640791476408 prot_P15700 + ATP + dCMP --> ADP + dCDP 0.0 r_1704_REV cytidylate kinase (dCMP) (reversible) 0.6446121633029441 prot_P15700 + ADP + dCDP --> ATP + dCMP 0.0006000000052154061 r_1705 cytosine exchange cytosine --> 0.0 @@ -1963,7 +1963,7 @@ r_1707_EXP_1 D-arabinose transport 12.279417568370668 prot_P39004 + D-arabinose r_1707_EXP_2 D-arabinose transport 21.95512360185767 prot_P32467 + D-arabinose --> D-arabinose 0.0 r_1707_REV_EXP_1 D-arabinose transport (reversible) 12.279417568370668 prot_P39004 + D-arabinose --> D-arabinose 0.0 r_1707_REV_EXP_2 D-arabinose transport (reversible) 21.95512360185767 prot_P32467 + D-arabinose --> D-arabinose 0.0 -r_1708 D-erythrose 4-phosphate transport D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.04594319592130103 +r_1708 D-erythrose 4-phosphate transport D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.0334524833254565 r_1708_REV D-erythrose 4-phosphate transport (reversible) D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.0 r_1709 D-fructose exchange D-fructose --> 0.0 r_1710 D-galactose exchange D-galactose --> 0.0 @@ -2030,38 +2030,38 @@ r_1751_REV dUDP diffusion (reversible) dUDP --> dUDP 0.0 r_1752 dUMP transport dUMP --> dUMP 0.0 r_1752_REV dUMP transport (reversible) dUMP --> dUMP 0.0 r_1753 episterol exchange episterol --> 0.0 -r_1754 ergosta-5,6,22,24,(28)-tetraen-3beta-ol transport ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.003720927744308719 +r_1754 ergosta-5,6,22,24,(28)-tetraen-3beta-ol transport ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.003720927744308722 r_1754_REV ergosta-5,6,22,24,(28)-tetraen-3beta-ol transport (reversible) ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 r_1757 ergosterol exchange ergosterol --> 0.0 r_1758 ergosterol transport ergosterol --> ergosterol 0.0 r_1758_REV ergosterol transport (reversible) ergosterol --> ergosterol 0.0 r_1759 ergosterol transport ergosterol --> ergosterol 0.0 r_1759_REV ergosterol transport (reversible) ergosterol --> ergosterol 0.0 -r_1761 ethanol exchange ethanol --> 0.01 -r_1762 ethanol transport ethanol --> ethanol 0.01 +r_1761 ethanol exchange ethanol --> 0.0 +r_1762 ethanol transport ethanol --> ethanol 0.0 r_1762_REV ethanol transport (reversible) ethanol --> ethanol 0.0 -r_1763 ethanol transport, mitochondrial ethanol --> ethanol 0.0 +r_1763 ethanol transport, mitochondrial ethanol --> ethanol 9.25992615918858e-12 r_1763_REV ethanol transport, mitochondrial (reversible) ethanol --> ethanol 0.0 r_1764 ethanolamine exchange ethanolamine --> 0.0 -r_1765 ethyl acetate exchange ethyl acetate --> 0.16778232905888193 +r_1765 ethyl acetate exchange ethyl acetate --> 0.12158141345131043 r_1766 farnesyl diphosphate transport farnesyl diphosphate --> farnesyl diphosphate 0.0 r_1766_REV farnesyl diphosphate transport (reversible) farnesyl diphosphate --> farnesyl diphosphate 0.0 r_1770 fatty acid transport 0.6366271866276696 prot_P38225 + decanoate --> decanoate 0.0 r_1770_REV fatty acid transport (reversible) 0.6366271866276696 prot_P38225 + decanoate --> decanoate 0.0 r_1771 fatty acid transport 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + laurate --> laurate 0.0 -r_1771_REV fatty acid transport (reversible) 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + laurate --> laurate 7.302847455517872e-06 +r_1771_REV fatty acid transport (reversible) 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + laurate --> laurate 0.0 r_1772 fatty acid transport 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + myristate --> myristate 0.0 r_1772_REV fatty acid transport (reversible) 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + myristate --> myristate 0.0 r_1774 fatty acid transport 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + palmitate --> palmitate 0.0 r_1774_REV fatty acid transport (reversible) 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + palmitate --> palmitate 0.0 -r_1775 fatty acid transport 0.44480530037780946 prot_P38225 + palmitoleate --> palmitoleate 1.9000000606814286e-05 +r_1775 fatty acid transport 0.44480530037780946 prot_P38225 + palmitoleate --> palmitoleate 0.0 r_1775_REV fatty acid transport (reversible) 0.44480530037780946 prot_P38225 + palmitoleate --> palmitoleate 0.0 r_1776 fatty acid transport octanoate --> octanoate 0.0 r_1776_REV fatty acid transport (reversible) octanoate --> octanoate 0.0 r_1777 myristate (n-C14:0) transport myristate --> myristate 0.0 r_1777_REV myristate (n-C14:0) transport (reversible) myristate --> myristate 0.0 r_1788 fecosterol exchange fecosterol --> 0.0 -r_1790 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 0.0 +r_1790 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 9.999999747364874e-07 r_1791 FMN exchange FMN --> 0.0 r_1792 folic acid exchange folate --> 0.0 r_1793 formate exchange formate --> 0.04471893772 @@ -2086,9 +2086,9 @@ r_1807 glutathione exchange glutathione --> 0.0 r_1808 glycerol exchange glycerol --> 0.0 r_1809 glycerol-3-phosphate shuttle glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_1809_REV glycerol-3-phosphate shuttle (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 -r_1810 L-glycine exchange L-glycine --> 0.047479654937039414 +r_1810 L-glycine exchange L-glycine --> 0.04747965493704179 r_1811 glycine transport 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 0.0 -r_1811_REV glycine transport (reversible) 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 1.900000061143747e-05 +r_1811_REV glycine transport (reversible) 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 1.9000000611588824e-05 r_1812 glycoaldehyde transport glycolaldehyde --> glycolaldehyde 0.0 r_1812_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 6.3400002545677125e-06 r_1813 glycoaldehyde transport glycolaldehyde --> glycolaldehyde 0.0 @@ -2107,7 +2107,7 @@ r_1821 guanosine kinase 0.5934259259259259 prot_standard + ATP + guanosine --> A r_1822 guanosine transport guanosine --> guanosine 0.0 r_1823 guanosine transport guanosine --> guanosine 0.0 r_1824 H+ diffusion H+ --> H+ 0.0 -r_1825 H+ diffusion H+ --> H+ 0.00744554842162075 +r_1825 H+ diffusion H+ --> H+ 0.007445548421619067 r_1825_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1826 H+ diffusion H+ --> H+ 0.0 r_1826_REV H+ diffusion (reversible) H+ --> H+ 0.0 @@ -2115,11 +2115,11 @@ r_1827 H+ diffusion H+ --> H+ 0.0 r_1827_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1829 H+ diffusion H+ --> H+ 0.0 r_1829_REV H+ diffusion (reversible) H+ --> H+ 0.0 -r_1830 H+ diffusion H+ --> H+ 0.00020021139528340022 +r_1830 H+ diffusion H+ --> H+ 0.0 r_1830_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1831 H+ diffusion H+ --> H+ 0.0 r_1831_REV H+ diffusion (reversible) H+ --> H+ 0.0 -r_1832 H+ exchange H+ <=> 0.5759799667276804 +r_1832 H+ exchange H+ <=> 0.6704140298075858 r_1833 hexacosanoyl-CoA transport hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_1833_REV hexacosanoyl-CoA transport (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_1834 hexadecanal exchange hexadecanal --> 0.0 @@ -2133,7 +2133,7 @@ r_1838_EXP_2 homocitrate synthase 10.507993633138625 prot_P48570 + 2-oxoglutarat r_1839 hydrogen peroxide transport hydrogen peroxide --> hydrogen peroxide 0.0 r_1839_REV hydrogen peroxide transport (reversible) hydrogen peroxide --> hydrogen peroxide 0.0 r_1840 hydroxymethylglutaryl-CoA transport 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.0 -r_1840_REV hydroxymethylglutaryl-CoA transport (reversible) 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.022347724063872188 +r_1840_REV hydroxymethylglutaryl-CoA transport (reversible) 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.022347724063862068 r_1841 hypoxanthine exchange hypoxanthine --> 0.0 r_1842 hypoxanthine transport hypoxanthine --> hypoxanthine 0.0 r_1842_REV hypoxanthine transport (reversible) hypoxanthine --> hypoxanthine 0.0 @@ -2293,13 +2293,13 @@ r_1928 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide C (C26 r_1928_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide C (C26) --> inositol phosphomannosylinositol phosphoceramide C (C26) 0.0 r_1929 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide D (C26) --> inositol phosphomannosylinositol phosphoceramide D (C26) 0.0 r_1929_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide D (C26) --> inositol phosphomannosylinositol phosphoceramide D (C26) 0.0 -r_1930 malate/oxaloacetate shuttle (S)-malate + oxaloacetate --> (S)-malate + oxaloacetate 0.00012860569855192147 +r_1930 malate/oxaloacetate shuttle (S)-malate + oxaloacetate --> (S)-malate + oxaloacetate 0.0 r_1930_REV malate/oxaloacetate shuttle (reversible) (S)-malate + oxaloacetate --> (S)-malate + oxaloacetate 0.0 r_1931 maltose exchange maltose --> 0.0 r_1932 mannan transport mannan --> mannan 0.0 r_1932_REV mannan transport (reversible) mannan --> mannan 0.070204 r_1935 methionine transport 6.982964031081571 prot_P48813 + L-methionine --> L-methionine 0.0 -r_1936 methylglyoxal synthase 1.1329040404040405 prot_standard + dihydroxyacetone phosphate --> methylglyoxal + phosphate 0.08445874855905258 +r_1936 methylglyoxal synthase 1.1329040404040405 prot_standard + dihydroxyacetone phosphate --> methylglyoxal + phosphate 0.0 r_1937 MIPC transport mannosylinositol phosphorylceramide A (C24) --> mannosylinositol phosphorylceramide A (C24) 0.0 r_1937_REV MIPC transport (reversible) mannosylinositol phosphorylceramide A (C24) --> mannosylinositol phosphorylceramide A (C24) 0.0 r_1938 MIPC transport mannosylinositol phosphorylceramide B (C24) --> mannosylinositol phosphorylceramide B (C24) 0.0 @@ -2323,8 +2323,8 @@ r_1946_REV MIPC transport (reversible) mannosylinositol phosphorylceramide D (C2 r_1947 myo-inositol exchange myo-inositol --> 0.0 r_1952 N,N'-diformyldityrosine exchange N,N'-diformyldityrosine --> 0.0 r_1963 NADP(+) transport NADP(+) --> NADP(+) 0.0 -r_1963_REV NADP(+) transport (reversible) NADP(+) --> NADP(+) 0.00744554842162075 -r_1964 NADPH transport NADPH --> NADPH 0.00744554842162075 +r_1963_REV NADP(+) transport (reversible) NADP(+) --> NADP(+) 0.007445548421619067 +r_1964 NADPH transport NADPH --> NADPH 0.007445548421619067 r_1964_REV NADPH transport (reversible) NADPH --> NADPH 0.0 r_1965 NH3 transport ammonium --> ammonium 0.0 r_1965_REV NH3 transport (reversible) ammonium --> ammonium 0.0 @@ -2340,13 +2340,13 @@ r_1972 NMN transport NMN --> NMN 0.0 r_1974 nucleoside-diphosphatase (dGDP) 0.5934259259259259 prot_standard + dGDP + H2O --> dGMP + H+ + phosphate 0.0 r_1975 nucleoside-triphosphatase (dGTP) 0.5934259259259259 prot_standard + dGTP + H2O --> dGDP + H+ + phosphate 0.0 r_1976 O-acetylcarnintine transport into mitochondria 1.094665810308139 prot_Q12289 + O-acetylcarnitine --> O-acetylcarnitine 0.0 -r_1977 O2 transport oxygen --> oxygen 0.003724620677312031 +r_1977 O2 transport oxygen --> oxygen 0.0037246206773103446 r_1977_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1978 O2 transport oxygen --> oxygen 3.7550227517851393 +r_1978 O2 transport oxygen --> oxygen 3.7887780432156113 r_1978_REV O2 transport (reversible) oxygen --> oxygen 0.0 r_1979 O2 transport oxygen --> oxygen 3.8504781436 r_1979_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1980 O2 transport oxygen --> oxygen 0.00015490854661425358 +r_1980 O2 transport oxygen --> oxygen 0.0 r_1980_REV O2 transport (reversible) oxygen --> oxygen 0.0 r_1981 octadecanoate (n-C18:0) transport 0.6366271866276696 prot_P38225 + stearate --> stearate 0.0 r_1981_REV octadecanoate (n-C18:0) transport (reversible) 0.6366271866276696 prot_P38225 + stearate --> stearate 0.0 @@ -2357,15 +2357,15 @@ r_1988_REV oxaloacetate transport (reversible) oxaloacetate --> oxaloacetate 0.0 r_1989 oxaloacetate(2-) exchange oxaloacetate --> 0.0 r_1990 oxidized glutathione uniport 6.850627360229916 prot_P40897 + glutathione disulfide --> glutathione disulfide 0.0 r_1991 oxidized thioredoxin transport TRX1 disulphide --> TRX1 disulphide 0.0 -r_1991_REV oxidized thioredoxin transport (reversible) TRX1 disulphide --> TRX1 disulphide 0.00015490854661425363 +r_1991_REV oxidized thioredoxin transport (reversible) TRX1 disulphide --> TRX1 disulphide 0.0 r_1992 oxygen exchange oxygen <-- -3.8504781436 r_1993 palmitate exchange palmitate --> 0.0 r_1994 palmitoleate exchange palmitoleate --> 0.0 r_1995 palmitoyl-CoA transport palmitoyl-CoA --> palmitoyl-CoA 0.0 r_1995_REV palmitoyl-CoA transport (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 -r_1996 panthetheine 4'-phosphate transport pantetheine 4'-phosphate --> pantetheine 4'-phosphate 1.900000061143747e-05 +r_1996 panthetheine 4'-phosphate transport pantetheine 4'-phosphate --> pantetheine 4'-phosphate 1.9000000611588824e-05 r_1996_REV panthetheine 4'-phosphate transport (reversible) pantetheine 4'-phosphate --> pantetheine 4'-phosphate 0.0 -r_1997 panthetheine-phosphate adenylyltransferase 3.214741247115812 prot_standard + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 1.9000000605489682e-05 +r_1997 panthetheine-phosphate adenylyltransferase 3.214741247115812 prot_standard + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 1.9000000611588824e-05 r_1998 PAP uniport adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0 r_1998_REV PAP uniport (reversible) adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0 r_1999 pectin exchange pectin --> 0.0 @@ -2376,7 +2376,7 @@ r_2002_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phen r_2003 phenylacetaldehyde transport phenylacetaldehyde --> phenylacetaldehyde 0.0 r_2003_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phenylacetaldehyde 0.0 r_2004 phenylalanine transport L-phenylalanine --> L-phenylalanine 0.0 -r_2005 phosphate exchange phosphate <=> -0.027912664680937338 +r_2005 phosphate exchange phosphate <=> -0.027912664680954827 r_2008 phosphate transport 2.5123737373737374 prot_P27514 + phosphate --> phosphate 0.0 r_2008_REV phosphate transport (reversible) 2.5123737373737374 prot_P27514 + phosphate --> phosphate 0.0 r_2020 potassium exchange potassium <=> -0.000362999993376434 @@ -2390,20 +2390,20 @@ r_2026 pyridoxamine kinase 0.07735564304461942 prot_P53727 + ATP + pyridoxamine r_2027 pyridoxamine phosphatase 11.27565182849182 prot_standard + H2O + pyridoxamine 5'-phosphate --> phosphate + pyridoxamine 0.0 r_2028 pyridoxine exchange pyridoxine --> 0.0 r_2029 pyridoxine kinase 0.08096311475409836 prot_P39988 + ATP + pyridoxine --> ADP + H+ + pyridoxine 5'-phosphate 0.0 -r_2030 pyrimidine phosphatase 3.5775737902860114 prot_standard + 5-amino-6-(5-phosphoribitylamino)uracil + H2O --> 5-amino-6-(D-ribitylamino)uracil + phosphate 9.999999710998968e-05 +r_2030 pyrimidine phosphatase 3.5775737902860114 prot_standard + 5-amino-6-(5-phosphoribitylamino)uracil + H2O --> 5-amino-6-(D-ribitylamino)uracil + phosphate 9.99999971099883e-05 r_2031 pyrimidine-nucleoside phosphorylase (uracil) 0.9660422049956934 prot_standard + phosphate + uridine --> alpha-D-ribose 1-phosphate(2-) + uracil 0.0 r_2031_REV pyrimidine-nucleoside phosphorylase (uracil) (reversible) 0.9660422049956934 prot_standard + alpha-D-ribose 1-phosphate(2-) + uracil --> phosphate + uridine 0.0 r_2032 pyrophosphate transport diphosphate --> diphosphate 0.0 -r_2032_REV pyrophosphate transport (reversible) diphosphate --> diphosphate 1.1404351045853218 +r_2032_REV pyrophosphate transport (reversible) diphosphate --> diphosphate 0.01766718019610752 r_2033 pyruvate exchange pyruvate --> 0.0 r_2034_EXP_1 pyruvate transport 0.010426331697901588 prot_P53157 + 0.011285052581323294 prot_P53311 + H+ + pyruvate --> H+ + pyruvate 0.0 r_2034_EXP_2 pyruvate transport 0.011066557295101342 prot_P38857 + 0.011401101108900353 prot_P53157 + H+ + pyruvate --> H+ + pyruvate 0.0 r_2036 quinolinate transport quinolinate --> quinolinate 0.0 r_2036_REV quinolinate transport (reversible) quinolinate --> quinolinate 0.0 -r_2037 reduced thioredoxin transport TRX1 --> TRX1 0.00015490854661425363 +r_2037 reduced thioredoxin transport TRX1 --> TRX1 0.0 r_2037_REV reduced thioredoxin transport (reversible) TRX1 --> TRX1 0.0 r_2038 riboflavin exchange riboflavin --> 0.0 -r_2039 riboflavin transport riboflavin --> riboflavin 0.0 +r_2039 riboflavin transport riboflavin --> riboflavin 9.999999747364874e-07 r_2040 riboflavin transport 71.18089610319483 prot_Q08777 + riboflavin --> riboflavin 0.0 r_2041_EXP_1 ribose transporter 11.163122614359402 prot_P39004 + D-ribose --> D-ribose 0.0 r_2041_EXP_2 ribose transporter 10.784451386239029 prot_P32467 + D-ribose --> D-ribose 0.0 @@ -2411,23 +2411,23 @@ r_2042 S-adenosyl-L-homocysteine transport S-adenosyl-L-homocysteine --> S-adeno r_2042_REV S-adenosyl-L-homocysteine transport (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.0 r_2043 S-adenosyl-L-methionine exchange S-adenosyl-L-methionine --> 0.0 r_2044 S-methyl-L-methionine exchange S-methyl-L-methionine --> 0.0 -r_2045 serine transport 7.412955094957308 prot_P48813 + L-serine --> L-serine 1.900000061143747e-05 +r_2045 serine transport 7.412955094957308 prot_P48813 + L-serine --> L-serine 1.9000000611588824e-05 r_2045_REV serine transport (reversible) 7.412955094957308 prot_P48813 + L-serine --> L-serine 0.0 r_2046 sn-glycero-3-phosphocholine exchange sn-glycero-3-phosphocholine --> 0.0 r_2049 sodium exchange sodium <=> -0.0003969999961555 r_2050 spermidine acetyltransferase 0.31953703703703706 prot_standard + acetyl-CoA + spermidine --> coenzyme A + H+ + N(1)-acetylspermidine 0.0 r_2051 spermidine exchange spermidine --> 0.0 r_2052 spermine exchange spermine --> 0.0 -r_2053 squalene transport squalene --> squalene 0.003724620677312031 +r_2053 squalene transport squalene --> squalene 0.0037246206773103446 r_2053_REV squalene transport (reversible) squalene --> squalene 0.0 -r_2054 squalene-2,3-epoxide transport (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.003724620677312031 +r_2054 squalene-2,3-epoxide transport (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.0037246206773103446 r_2054_REV squalene-2,3-epoxide transport (reversible) (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.0 r_2055 stearate exchange stearate --> 0.0 r_2056 succinate exchange succinate --> 0.0 r_2057 succinate transport succinate --> succinate 0.0 r_2057_REV succinate transport (reversible) succinate --> succinate 0.0 r_2058 sucrose exchange sucrose --> 0.0 -r_2060 sulphate exchange sulphate <=> -0.013924916568870642 +r_2060 sulphate exchange sulphate <=> -0.013924916568870795 r_2061 sulphite exchange sulphite --> 0.0 r_2062 taurine exchange taurine --> 0.0 r_2063 tetracosanoyl-CoA transport tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 @@ -2464,19 +2464,19 @@ r_2093 valine transport L-valine --> L-valine 0.0 r_2093_REV valine transport (reversible) L-valine --> L-valine 0.031460454977486 r_2094_EXP_1 water diffusion 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_2094_EXP_2 water diffusion 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_2094_REV_EXP_1 water diffusion (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.003724620677312031 +r_2094_REV_EXP_1 water diffusion (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0037246206773103446 r_2094_REV_EXP_2 water diffusion (reversible) 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_2095 water diffusion H2O --> H2O 0.0 r_2095_REV water diffusion (reversible) H2O --> H2O 0.0 r_2096 water diffusion H2O --> H2O 0.0 -r_2096_REV water diffusion (reversible) H2O --> H2O 7.971896699160814 +r_2096_REV water diffusion (reversible) H2O --> H2O 8.098807079965 r_2097 water diffusion H2O --> H2O 0.0 r_2097_REV water diffusion (reversible) H2O --> H2O 0.0 r_2098 water diffusion H2O --> H2O 0.0 -r_2098_REV water diffusion (reversible) H2O --> H2O 0.00015490854661425366 +r_2098_REV water diffusion (reversible) H2O --> H2O 0.0 r_2099 water diffusion H2O --> H2O 0.0 r_2099_REV water diffusion (reversible) H2O --> H2O 0.0 -r_2100 water exchange H2O <=> 5.932272301617025 +r_2100 water exchange H2O <=> 5.9328944757129065 r_2101 xanthine transport 9H-xanthine --> 9H-xanthine 0.0 r_2101_REV xanthine transport (reversible) 9H-xanthine --> 9H-xanthine 0.0 r_2102 xanthosine exchange xanthosine --> 0.0 @@ -2486,30 +2486,30 @@ r_2105_EXP_1 xylitol transport 157.39707095807333 prot_P54854 + xylitol --> xyli r_2105_EXP_2 xylitol transport 0.8243345214851523 prot_P23900 + xylitol --> xylitol 0.0 r_2105_REV_EXP_1 xylitol transport (reversible) 157.39707095807333 prot_P54854 + xylitol --> xylitol 0.0 r_2105_REV_EXP_2 xylitol transport (reversible) 0.8243345214851523 prot_P23900 + xylitol --> xylitol 0.0 -r_2106 zymosterol exchange zymosterol --> 3.692933003312214e-06 +r_2106 zymosterol exchange zymosterol --> 3.6929330016225934e-06 r_2107_EXP_1 zymosterol transport 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 0.0 r_2107_EXP_2 zymosterol transport 254.30179320863886 prot_Q08409 + zymosterol --> zymosterol 0.0 -r_2107_REV_EXP_1 zymosterol transport (reversible) 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 3.692933003312214e-06 +r_2107_REV_EXP_1 zymosterol transport (reversible) 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 3.6929330016225934e-06 r_2107_REV_EXP_2 zymosterol transport (reversible) 254.30179320863886 prot_Q08409 + zymosterol --> zymosterol 0.0 r_2108 lipid pseudoreaction - merge lipid backbone + lipid chain --> lipid 0.1 r_2111 growth biomass --> 0.1 r_2112 kynurenine aminotransferase 0.06921227197346601 prot_P47039 + L-kynurenine + pyruvate --> H2O + L-alanine + kynurenic acid 0.0 r_2112_REV kynurenine aminotransferase (reversible) 0.009033549783549784 prot_P47039 + H2O + L-alanine + kynurenic acid --> L-kynurenine + pyruvate 0.0 r_2113 spontaneous kynurenic acid to quinaldic acid 0.41264716703458426 prot_standard + 2.0 H+ + NADPH + kynurenic acid --> H2O + NADP(+) + quinaldic acid 0.0 -r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.41264716703458426 prot_standard + 2-amino-3-carboxymuconate-6-semialdehyde --> H+ + H2O + quinolinate 0.0006069999974000248 +r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.41264716703458426 prot_standard + 2-amino-3-carboxymuconate-6-semialdehyde --> H+ + H2O + quinolinate 0.0006069999973989104 r_2115_EXP_1 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.03339649287148808 prot_P38113 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.0 -r_2115_EXP_2 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.011373148148148148 prot_P00330 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.20127967663650642 +r_2115_EXP_2 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.011373148148148148 prot_P00330 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.13786055257056973 r_2116_EXP_1 acetaldehyde dehydrogenase 0.06942013888888889 prot_Q04458 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_2 acetaldehyde dehydrogenase 0.483596214511041 prot_P47771 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_3 acetaldehyde dehydrogenase 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_4 acetaldehyde dehydrogenase 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 -r_2117 phenylalanine transaminase 0.05744797801334904 prot_P38840 + L-phenylalanine + pyruvate --> keto-phenylpyruvate + L-alanine 0.043625178914844846 +r_2117 phenylalanine transaminase 0.05744797801334904 prot_P38840 + L-phenylalanine + pyruvate --> keto-phenylpyruvate + L-alanine 0.043625178914845436 r_2117_REV phenylalanine transaminase (reversible) 0.010556998556998556 prot_P38840 + keto-phenylpyruvate + L-alanine --> L-phenylalanine + pyruvate 0.0 r_2118 tryptophan transaminase 0.05744797801334904 prot_P38840 + keto-phenylpyruvate + L-tryptophan --> indole-3-pyruvate + L-phenylalanine 0.0 r_2119 tyrosine transaminase 0.010556998556998556 prot_P38840 + 3-(4-hydroxyphenyl)pyruvate + L-alanine --> L-tyrosine + pyruvate 0.012302566079285501 r_2119_REV tyrosine transaminase (reversible) 0.11696243005595523 prot_P38840 + L-tyrosine + pyruvate --> 3-(4-hydroxyphenyl)pyruvate + L-alanine 0.0 r_2125 coenzyme A: cytoplasm to LP coenzyme A --> coenzyme A 0.0 -r_2125_REV coenzyme A: cytoplasm to LP (reversible) coenzyme A --> coenzyme A 0.0007027567012357741 +r_2125_REV coenzyme A: cytoplasm to LP (reversible) coenzyme A --> coenzyme A 0.0013878634961654581 r_2126 sedoheptulose bisphosphatase 2.051719576719577 prot_P36136 + H2O + sedoheptulose 1,7-bisphosphate --> phosphate + sedoheptulose 7-phosphate 0.0 r_2129 proton leak H+ --> H+ 0.0 r_2131 isocitrate dehydrogenase 0.47807539682539685 prot_P21954 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.0 @@ -2521,7 +2521,7 @@ r_2136_REV 14-demethyllanosterol transport (reversible) 14-demethyllanosterol -- r_2137 ergosta-5,7,22,24(28)-tetraen-3beta-ol exchange ergosta-5,7,22,24(28)-tetraen-3beta-ol --> 0.0 r_2139 ergosta-5,7,22,24(28)-tetraen-3beta-ol transport ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 r_2139_REV ergosta-5,7,22,24(28)-tetraen-3beta-ol transport (reversible) ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 -r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 27.714912457481013 prot_P07149 + 25.079771343596047 prot_P19097 + acetyl-CoA + 21.0 H+ + 7.0 malonyl-CoA + 14.0 NADPH --> 7.0 carbon dioxide + 7.0 coenzyme A + 7.0 H2O + 14.0 NADP(+) + palmitoyl-CoA 0.01637868784444658 +r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 27.714912457481013 prot_P07149 + 25.079771343596047 prot_P19097 + acetyl-CoA + 21.0 H+ + 7.0 malonyl-CoA + 14.0 NADPH --> 7.0 carbon dioxide + 7.0 coenzyme A + 7.0 H2O + 14.0 NADP(+) + palmitoyl-CoA 0.016359687843839763 r_2141 fatty-acyl-CoA synthase (n-C18:0CoA) 50.82022222222222 prot_P07149 + 45.98822222222222 prot_P19097 + acetyl-CoA + 24.0 H+ + 8.0 malonyl-CoA + 16.0 NADPH --> 8.0 carbon dioxide + 8.0 coenzyme A + 8.0 H2O + 16.0 NADP(+) + stearoyl-CoA 0.0 r_2142 B-ketoacyl-ACP synthase (acetoacetyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + acetyl-ACP + carboxyacetyl-ACP --> carbon dioxide + ACP1 + acetoacetyl-ACP 0.0 r_2143 B-ketoacyl-ACP synthase (3-oxo-hexanoyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + carboxyacetyl-ACP + butanoyl-ACP --> carbon dioxide + ACP1 + 3-oxo-hexanoyl-ACP 0.0 @@ -2538,9 +2538,9 @@ r_2150_REV 3-hydroxyacyl-thioester dehydratase (trans-oct-2-enoyl-ACP) (reversib r_2151 enoyl-ACP reductase (butanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NADPH + trans-but-2-enoyl-ACP --> NADP(+) + butanoyl-ACP 0.0 r_2152 enoyl-ACP reductase (hexanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NADPH + trans-hex-2-enoyl-ACP --> NADP(+) + hexanoyl-ACP 0.0 r_2153 enoyl-ACP reductase (octanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NADPH + trans-oct-2-enoyl-ACP --> NADP(+) + octanoyl-ACP 0.0 -r_2154 elongase I (3-oxotetradecanoyl-CoA) 0.36517429674617 prot_P39540 + lauroyl-CoA + malonyl-CoA + H+ --> carbon dioxide + coenzyme A + 3-oxotetradecanoyl-CoA 7.302847455517871e-06 -r_2155 elongase I (3-oxopalmitoyl-CoA) 0.36517429674617 prot_P39540 + malonyl-CoA + H+ + myristoyl-CoA --> carbon dioxide + coenzyme A + 3-oxopalmitoyl-CoA 7.302847455517871e-06 -r_2156 elongase II (3-oxooctadecanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + palmitoyl-CoA --> carbon dioxide + coenzyme A + 3-oxooctadecanoyl-CoA 0.0038863062260324375 +r_2154 elongase I (3-oxotetradecanoyl-CoA) 0.36517429674617 prot_P39540 + lauroyl-CoA + malonyl-CoA + H+ --> carbon dioxide + coenzyme A + 3-oxotetradecanoyl-CoA 0.0 +r_2155 elongase I (3-oxopalmitoyl-CoA) 0.36517429674617 prot_P39540 + malonyl-CoA + H+ + myristoyl-CoA --> carbon dioxide + coenzyme A + 3-oxopalmitoyl-CoA 0.0 +r_2156 elongase II (3-oxooctadecanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + palmitoyl-CoA --> carbon dioxide + coenzyme A + 3-oxooctadecanoyl-CoA 0.0038790033785769183 r_2157_EXP_1 elongase II or III (3-oxoicosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + stearoyl-CoA --> carbon dioxide + coenzyme A + 3-oxoicosanoyl-CoA 0.0 r_2157_EXP_2 elongase II or III (3-oxoicosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + stearoyl-CoA --> carbon dioxide + coenzyme A + 3-oxoicosanoyl-CoA 0.0 r_2158_EXP_1 elongase II or III (3-oxodocosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + icosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxodocosanoyl-CoA 0.0 @@ -2548,18 +2548,18 @@ r_2158_EXP_2 elongase II or III (3-oxodocosanoyl-CoA) 0.49218897590613386 prot_P r_2159_EXP_1 elongase II or III (3-oxotetracosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + docosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxotetracosanoyl-CoA 0.0 r_2159_EXP_2 elongase II or III (3-oxotetracosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + docosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxotetracosanoyl-CoA 0.0 r_2160 elongase III (3-oxohexacosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + tetracosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxohexacosanoyl-CoA 0.0 -r_2161 B-ketoacyl-CoA reductase ((S)-3-hydroxytetradecanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxotetradecanoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxytetradecanoyl-CoA 7.302847455517871e-06 -r_2162 B-ketoacyl-CoA reductase ((S)-3-hydroxypalmitoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxopalmitoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxypalmitoyl-CoA 7.302847455517871e-06 -r_2163 B-ketoacyl-CoA reductase (3-hydroxyoctadecanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxooctadecanoyl-CoA + NADPH --> NADP(+) + 3-hydroxyoctadecanoyl-CoA 0.0038863062260324375 +r_2161 B-ketoacyl-CoA reductase ((S)-3-hydroxytetradecanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxotetradecanoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxytetradecanoyl-CoA 0.0 +r_2162 B-ketoacyl-CoA reductase ((S)-3-hydroxypalmitoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxopalmitoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxypalmitoyl-CoA 0.0 +r_2163 B-ketoacyl-CoA reductase (3-hydroxyoctadecanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxooctadecanoyl-CoA + NADPH --> NADP(+) + 3-hydroxyoctadecanoyl-CoA 0.0038790033785769183 r_2164 B-ketoacyl-CoA reductase (3-hydroxyicosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxoicosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxyicosanoyl-CoA 0.0 r_2165 B-ketoacyl-CoA reductase (3-hydroxydocosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxodocosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxydocosanoyl-CoA 0.0 r_2166 B-ketoacyl-CoA reductase (3-hydroxytetracosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxotetracosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxytetracosanoyl-CoA 0.0 r_2167 B-ketoacyl-CoA reductase ((S)-3-hydroxyhexacosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxohexacosanoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxyhexacosanoyl-CoA 0.0 -r_2168 B-hydroxyacyl-CoA dehydratase (trans-tetradec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxytetradecanoyl-CoA --> H2O + trans-tetradec-2-enoyl-CoA 7.302847455517871e-06 +r_2168 B-hydroxyacyl-CoA dehydratase (trans-tetradec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxytetradecanoyl-CoA --> H2O + trans-tetradec-2-enoyl-CoA 0.0 r_2168_REV B-hydroxyacyl-CoA dehydratase (trans-tetradec-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-tetradec-2-enoyl-CoA --> (S)-3-hydroxytetradecanoyl-CoA 0.0 -r_2169 B-hydroxyacyl-CoA dehydratase (trans-hexadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxypalmitoyl-CoA --> H2O + trans-hexadec-2-enoyl-CoA 7.302847455517871e-06 +r_2169 B-hydroxyacyl-CoA dehydratase (trans-hexadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxypalmitoyl-CoA --> H2O + trans-hexadec-2-enoyl-CoA 0.0 r_2169_REV B-hydroxyacyl-CoA dehydratase (trans-hexadec-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-hexadec-2-enoyl-CoA --> (S)-3-hydroxypalmitoyl-CoA 0.0 -r_2170 B-hydroxyacyl-CoA dehydratase (trans-octadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxyoctadecanoyl-CoA --> H2O + trans-octadec-2-enoyl-CoA 0.0038863062260324375 +r_2170 B-hydroxyacyl-CoA dehydratase (trans-octadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxyoctadecanoyl-CoA --> H2O + trans-octadec-2-enoyl-CoA 0.0038790033785769183 r_2170_REV B-hydroxyacyl-CoA dehydratase (trans-octadec-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-octadec-2-enoyl-CoA --> 3-hydroxyoctadecanoyl-CoA 0.0 r_2171 B-hydroxyacyl-CoA dehydratase (trans-icos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxyicosanoyl-CoA --> H2O + trans-icos-2-enoyl-CoA 0.0 r_2171_REV B-hydroxyacyl-CoA dehydratase (trans-icos-2-enoyl-CoA) (reversible) 7.243203309692672e-06 prot_P40857 + H2O + trans-icos-2-enoyl-CoA --> 3-hydroxyicosanoyl-CoA 0.0 @@ -2568,15 +2568,15 @@ r_2172_REV B-hydroxyacyl-CoA dehydratase (trans-docos-2-enoyl-CoA) (reversible) r_2173 B-hydroxyacyl-CoA dehydratase (trans-tetracos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxytetracosanoyl-CoA --> H2O + trans-tetracos-2-enoyl-CoA 0.0 r_2174 B-hydroxyacyl-CoA dehydratase (trans-hexacos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxyhexacosanoyl-CoA --> H2O + trans-hexacos-2-enoyl-CoA 0.0 r_2174_REV B-hydroxyacyl-CoA dehydratase (trans-hexacos-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-hexacos-2-enoyl-CoA --> (S)-3-hydroxyhexacosanoyl-CoA 0.0 -r_2175 trans-2-enoyl-CoA reductase (n-C14:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-tetradec-2-enoyl-CoA --> myristoyl-CoA + NADP(+) 7.302847455517871e-06 -r_2176 trans-2-enoyl-CoA reductase (n-C16:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexadec-2-enoyl-CoA --> palmitoyl-CoA + NADP(+) 7.302847455517871e-06 -r_2177 trans-2-enoyl-CoA reductase (n-C18:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-octadec-2-enoyl-CoA --> stearoyl-CoA + NADP(+) 0.0038863062260324375 +r_2175 trans-2-enoyl-CoA reductase (n-C14:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-tetradec-2-enoyl-CoA --> myristoyl-CoA + NADP(+) 0.0 +r_2176 trans-2-enoyl-CoA reductase (n-C16:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexadec-2-enoyl-CoA --> palmitoyl-CoA + NADP(+) 0.0 +r_2177 trans-2-enoyl-CoA reductase (n-C18:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-octadec-2-enoyl-CoA --> stearoyl-CoA + NADP(+) 0.0038790033785769183 r_2178 trans-2-enoyl-CoA reductase (n-C20:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-icos-2-enoyl-CoA --> icosanoyl-CoA + NADP(+) 0.0 r_2179 trans-2-enoyl-CoA reductase (n-C22:0CoA) 3.5110799393544463 prot_Q99190 + H+ + NADPH + trans-docos-2-enoyl-CoA --> docosanoyl-CoA + NADP(+) 0.0 r_2180 trans-2-enoyl-CoA reductase (n-C24:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-tetracos-2-enoyl-CoA --> tetracosanoyl-CoA + NADP(+) 0.0 r_2181 trans-2-enoyl-CoA reductase (n-C26:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexacos-2-enoyl-CoA --> NADP(+) + hexacosanoyl-CoA 0.0 -r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 13.846040131031963 prot_P21147 + H+ + palmitoyl-CoA + oxygen + NADH --> 2.0 H2O + palmitoleoyl-CoA(4-) + NAD 0.009346435743774896 -r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 46.3515873015873 prot_P21147 + H+ + stearoyl-CoA + oxygen + NADH --> 2.0 H2O + NAD + oleoyl-CoA 0.0030896614901154127 +r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 13.846040131031963 prot_P21147 + H+ + palmitoyl-CoA + oxygen + NADH --> 2.0 H2O + palmitoleoyl-CoA(4-) + NAD 0.00932743574316808 +r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 46.3515873015873 prot_P21147 + H+ + stearoyl-CoA + oxygen + NADH --> 2.0 H2O + NAD + oleoyl-CoA 0.0030823586426598935 r_2184 octanoate (n-C8:0) transport octanoate --> octanoate 0.0 r_2184_REV octanoate (n-C8:0) transport (reversible) octanoate --> octanoate 0.0 r_2185 decanoate (n-C10:0) transport decanoate --> decanoate 0.0 @@ -2593,7 +2593,7 @@ r_2191_REV hexanoate (n-C6:0) transport (reversible) 21.555294308917937 prot_P53 r_2192 octadecenoate (n-C18:1) transport 1.1688088711408016 prot_P38225 + oleate --> oleate 0.0 r_2192_REV octadecenoate (n-C18:1) transport (reversible) 1.1688088711408016 prot_P38225 + oleate --> oleate 0.0 r_2193 myristate exchange myristate --> 0.0 -r_2194 fatty-acid--CoA ligase (dodecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + laurate --> lauroyl-CoA + AMP + diphosphate 7.302847455517871e-06 +r_2194 fatty-acid--CoA ligase (dodecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + laurate --> lauroyl-CoA + AMP + diphosphate 0.0 r_2194_REV fatty-acid--CoA ligase (dodecanoate), ER membrane (reversible) 4.27578504719294 prot_P30624 + lauroyl-CoA + AMP + diphosphate --> coenzyme A + ATP + laurate 0.0 r_2195_EXP_1 fatty-acid--CoA ligase (tetradecanoate), ER membrane 740.1053639846743 prot_P47912 + coenzyme A + ATP + myristate --> myristoyl-CoA + AMP + diphosphate 0.0 r_2195_EXP_2 fatty-acid--CoA ligase (tetradecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + myristate --> myristoyl-CoA + AMP + diphosphate 0.0 @@ -2605,7 +2605,7 @@ r_2196_REV_EXP_1 fatty-acid--CoA ligase (hexadecanoate), ER membrane (reversible r_2196_REV_EXP_2 fatty-acid--CoA ligase (hexadecanoate), ER membrane (reversible) 4.27578504719294 prot_P30624 + palmitoyl-CoA + AMP + diphosphate --> coenzyme A + ATP + palmitate 0.0 r_2197_EXP_1 fatty-acid--CoA ligase (hexadecenoate), ER membrane 789.6458183044103 prot_P47912 + coenzyme A + ATP + palmitoleate --> palmitoleoyl-CoA(4-) + AMP + diphosphate 0.0 r_2197_EXP_2 fatty-acid--CoA ligase (hexadecenoate), ER membrane 795.767420607649 prot_P30624 + coenzyme A + ATP + palmitoleate --> palmitoleoyl-CoA(4-) + AMP + diphosphate 0.0 -r_2197_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), ER membrane (reversible) 3.189962202455639 prot_P47912 + palmitoleoyl-CoA(4-) + AMP + diphosphate --> coenzyme A + ATP + palmitoleate 0.0 +r_2197_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), ER membrane (reversible) 3.189962202455639 prot_P47912 + palmitoleoyl-CoA(4-) + AMP + diphosphate --> coenzyme A + ATP + palmitoleate 0.0005840846230801189 r_2197_REV_EXP_2 fatty-acid--CoA ligase (hexadecenoate), ER membrane (reversible) 4.583272040765874 prot_P30624 + palmitoleoyl-CoA(4-) + AMP + diphosphate --> coenzyme A + ATP + palmitoleate 0.0 r_2198_EXP_1 fatty-acid--CoA ligase (octadecanoate), ER membrane 740.1053639846743 prot_P47912 + coenzyme A + ATP + stearate --> stearoyl-CoA + AMP + diphosphate 0.0 r_2198_EXP_2 fatty-acid--CoA ligase (octadecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + stearate --> stearoyl-CoA + AMP + diphosphate 0.0 @@ -2627,7 +2627,7 @@ r_2202_REV_EXP_1 fatty-acid--CoA ligase (hexadecanoate), lipid particle (reversi r_2202_REV_EXP_2 fatty-acid--CoA ligase (hexadecanoate), lipid particle (reversible) 4.27578504719294 prot_P30624 + diphosphate + AMP + palmitoyl-CoA --> coenzyme A + ATP + palmitate 0.0 r_2203_EXP_1 fatty-acid--CoA ligase (hexadecenoate), lipid particle 376.2385922203972 prot_P47912 + coenzyme A + ATP + palmitoleate --> diphosphate + AMP + palmitoleoyl-CoA(4-) 0.0 r_2203_EXP_2 fatty-acid--CoA ligase (hexadecenoate), lipid particle 379.1553214416692 prot_P30624 + coenzyme A + ATP + palmitoleate --> diphosphate + AMP + palmitoleoyl-CoA(4-) 0.0 -r_2203_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), lipid particle (reversible) 3.189962202455639 prot_P47912 + diphosphate + AMP + palmitoleoyl-CoA(4-) --> coenzyme A + ATP + palmitoleate 0.0006030846236869334 +r_2203_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), lipid particle (reversible) 3.189962202455639 prot_P47912 + diphosphate + AMP + palmitoleoyl-CoA(4-) --> coenzyme A + ATP + palmitoleate 0.0 r_2203_REV_EXP_2 fatty-acid--CoA ligase (hexadecenoate), lipid particle (reversible) 4.583272040765874 prot_P30624 + diphosphate + AMP + palmitoleoyl-CoA(4-) --> coenzyme A + ATP + palmitoleate 0.0 r_2204_EXP_1 fatty-acid--CoA ligase (octadecanoate), lipid particle 740.1053639846743 prot_P47912 + coenzyme A + ATP + stearate --> diphosphate + AMP + stearoyl-CoA 0.0 r_2204_EXP_2 fatty-acid--CoA ligase (octadecanoate), lipid particle 745.8429118773946 prot_P30624 + coenzyme A + ATP + stearate --> diphosphate + AMP + stearoyl-CoA 0.0 @@ -2635,13 +2635,13 @@ r_2204_REV_EXP_1 fatty-acid--CoA ligase (octadecanoate), lipid particle (reversi r_2204_REV_EXP_2 fatty-acid--CoA ligase (octadecanoate), lipid particle (reversible) 4.27578504719294 prot_P30624 + diphosphate + AMP + stearoyl-CoA --> coenzyme A + ATP + stearate 0.0 r_2205_EXP_1 fatty-acid--CoA ligase (octadecenoate), lipid particle 1069.982099501589 prot_P47912 + coenzyme A + ATP + oleate --> diphosphate + AMP + oleoyl-CoA 0.0 r_2205_EXP_2 fatty-acid--CoA ligase (octadecenoate), lipid particle 1078.2769637722536 prot_P30624 + coenzyme A + ATP + oleate --> diphosphate + AMP + oleoyl-CoA 0.0 -r_2205_REV_EXP_1 fatty-acid--CoA ligase (octadecenoate), lipid particle (reversible) 3.15048984865542 prot_P47912 + diphosphate + AMP + oleoyl-CoA --> coenzyme A + ATP + oleate 7.302847455517871e-06 +r_2205_REV_EXP_1 fatty-acid--CoA ligase (octadecenoate), lipid particle (reversible) 3.15048984865542 prot_P47912 + diphosphate + AMP + oleoyl-CoA --> coenzyme A + ATP + oleate 0.0 r_2205_REV_EXP_2 fatty-acid--CoA ligase (octadecenoate), lipid particle (reversible) 4.477103447320649 prot_P30624 + diphosphate + AMP + oleoyl-CoA --> coenzyme A + ATP + oleate 0.0 -r_2206 fatty-acid--CoA ligase (hexadecenoate), peroxisome 799.2145593869732 prot_P39518 + ATP + coenzyme A + palmitoleate --> AMP + diphosphate + palmitoleoyl-CoA(4-) 1.9000000606814286e-05 +r_2206 fatty-acid--CoA ligase (hexadecenoate), peroxisome 799.2145593869732 prot_P39518 + ATP + coenzyme A + palmitoleate --> AMP + diphosphate + palmitoleoyl-CoA(4-) 0.0 r_2206_REV fatty-acid--CoA ligase (hexadecenoate), peroxisome (reversible) 35.32799384939581 prot_P39518 + AMP + diphosphate + palmitoleoyl-CoA(4-) --> ATP + coenzyme A + palmitoleate 0.0 r_2207 fatty-acid--CoA ligase (octadecanoate), peroxisome 799.2145593869732 prot_P39518 + ATP + coenzyme A + stearate --> AMP + diphosphate + stearoyl-CoA 0.0 r_2207_REV fatty-acid--CoA ligase (octadecanoate), peroxisome (reversible) 33.739859453840296 prot_P39518 + AMP + diphosphate + stearoyl-CoA --> ATP + coenzyme A + stearate 0.0 -r_2208 fatty-acid--CoA ligase (octadecenoate), peroxisome 799.2145593869732 prot_P39518 + ATP + coenzyme A + oleate --> AMP + diphosphate + oleoyl-CoA 7.302847455517871e-06 +r_2208 fatty-acid--CoA ligase (octadecenoate), peroxisome 799.2145593869732 prot_P39518 + ATP + coenzyme A + oleate --> AMP + diphosphate + oleoyl-CoA 0.0 r_2208_REV fatty-acid--CoA ligase (octadecenoate), peroxisome (reversible) 34.05612082872681 prot_P39518 + AMP + diphosphate + oleoyl-CoA --> ATP + coenzyme A + oleate 0.0 r_2209 fatty-acid--CoA ligase (arachidate), cell envelope 746.6187739463601 prot_P39002 + ATP + coenzyme A + arachidate --> AMP + diphosphate + icosanoyl-CoA 0.0 r_2209_REV fatty-acid--CoA ligase (arachidate), cell envelope (reversible) 16.828378818782944 prot_P39002 + AMP + diphosphate + icosanoyl-CoA --> ATP + coenzyme A + arachidate 0.0 @@ -2677,88 +2677,88 @@ r_2229 butyrate (n-C4:0) transport, cytoplasm-peroxisome butyrate --> butyrate 0 r_2229_REV butyrate (n-C4:0) transport, cytoplasm-peroxisome (reversible) butyrate --> butyrate 0.0 r_2230 hexanoate (n-C6:0) transport, cytoplasm-peroxisome hexanoate --> hexanoate 0.0 r_2230_REV hexanoate (n-C6:0) transport, cytoplasm-peroxisome (reversible) hexanoate --> hexanoate 0.0 -r_2231 octadecenoate (n-C18:1) transport, cytoplasm-peroxisome 58.44825801339124 prot_P34230 + 60.19281147982475 prot_P41909 + oleate --> oleate 7.302847455517871e-06 +r_2231 octadecenoate (n-C18:1) transport, cytoplasm-peroxisome 58.44825801339124 prot_P34230 + 60.19281147982475 prot_P41909 + oleate --> oleate 0.0 r_2231_REV octadecenoate (n-C18:1) transport, cytoplasm-peroxisome (reversible) 58.44825801339124 prot_P34230 + 60.19281147982475 prot_P41909 + oleate --> oleate 0.0 r_2232 peroxisomal acyl-CoA thioesterase (4:0) 0.12566955088586731 prot_P41903 + H2O + butanoyl-CoA --> coenzyme A + H+ + butyrate 0.0 r_2233 peroxisomal acyl-CoA thioesterase (6:0) 931.9444444444443 prot_P41903 + H2O + hexanoyl-CoA --> coenzyme A + 5.0 H+ + hexanoate 0.0 r_2234 peroxisomal acyl-CoA thioesterase (16:1) 0.12566955088586731 prot_P41903 + H2O + palmitoleoyl-CoA(4-) --> coenzyme A + H+ + palmitoleate 0.0 r_2235 peroxisomal acyl-CoA thioesterase (18:1) 0.12566955088586731 prot_P41903 + H2O + oleoyl-CoA --> coenzyme A + H+ + oleate 0.0 -r_2236 acyl-CoA oxidase (butanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + butanoyl-CoA --> hydrogen peroxide + trans-but-2-enoyl-CoA 1.9000000606814286e-05 -r_2237 acyl-CoA oxidase (hexanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + hexanoyl-CoA --> hydrogen peroxide + trans-hex-2-enoyl-CoA 1.9000000606814286e-05 -r_2238 acyl-CoA oxidase (octanoyl-CoA) 6.727665706051873 prot_P13711 + octanoyl-CoA + oxygen --> hydrogen peroxide + trans-oct-2-enoyl-CoA 1.9000000606814286e-05 +r_2236 acyl-CoA oxidase (butanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + butanoyl-CoA --> hydrogen peroxide + trans-but-2-enoyl-CoA 0.0 +r_2237 acyl-CoA oxidase (hexanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + hexanoyl-CoA --> hydrogen peroxide + trans-hex-2-enoyl-CoA 0.0 +r_2238 acyl-CoA oxidase (octanoyl-CoA) 6.727665706051873 prot_P13711 + octanoyl-CoA + oxygen --> hydrogen peroxide + trans-oct-2-enoyl-CoA 0.0 r_2239 acyl-CoA oxidase (icosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + icosanoyl-CoA --> hydrogen peroxide + trans-icos-2-enoyl-CoA 0.0 r_2240 acyl-CoA oxidase (docosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + docosanoyl-CoA --> hydrogen peroxide + trans-docos-2-enoyl-CoA 0.0 r_2241 acyl-CoA oxidase (tetracosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + tetracosanoyl-CoA --> hydrogen peroxide + trans-tetracos-2-enoyl-CoA 0.0 -r_2242 acyl-CoA oxidase (palmitoleoyl-CoA) 2.7176949941792783 prot_P13711 + 4.0 H+ + oxygen + palmitoleoyl-CoA(4-) --> hydrogen peroxide + trans-2,cis-9-hexadecadienoyl-CoA 1.9000000606814286e-05 -r_2243 acyl-CoA oxidase (cis-tetradec-7-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-tetradec-7-enoyl-CoA --> hydrogen peroxide + trans-2,cis-7-tetradecadienoyl-CoA 1.9000000606814286e-05 -r_2244 acyl-CoA oxidase (cis-dodec-5-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-dodec-5-enoyl-CoA --> hydrogen peroxide + trans-2,cis-5-dodecadienoyl-CoA 1.9000000606814286e-05 -r_2245 acyl-CoA oxidase (oleoyl-CoA) 2.7176949941792783 prot_P13711 + oleoyl-CoA + oxygen --> hydrogen peroxide + trans-2,cis-9-octadecadienoyl-CoA 7.302847455517871e-06 -r_2246 acyl-CoA oxidase (cis-hexadec-7-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-hexadec-7-enoyl-CoA --> hydrogen peroxide + trans-2,cis-7-hexadecadienoyl-CoA 7.302847455517871e-06 -r_2247 acyl-CoA oxidase (cis-tetradec-5-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-tetradec-5-enoyl-CoA --> hydrogen peroxide + trans-2,cis-5-tetradecadienoyl-CoA 7.302847455517871e-06 -r_2248 2-enoyl-CoA hydratase (3-hydroxydecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dec-2-enoyl-CoA --> (R)-3-hydroxydecanoyl-CoA 1.9000000606814286e-05 -r_2249 2-enoyl-CoA hydratase (3-hydroxydodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dodec-2-enoyl-CoA --> (R)-3-hydroxylauroyl-CoA 1.9000000606814286e-05 -r_2250 2-enoyl-CoA hydratase (3-hydroxytetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetradec-2-enoyl-CoA --> (S)-3-hydroxytetradecanoyl-CoA 7.302847455517871e-06 +r_2242 acyl-CoA oxidase (palmitoleoyl-CoA) 2.7176949941792783 prot_P13711 + 4.0 H+ + oxygen + palmitoleoyl-CoA(4-) --> hydrogen peroxide + trans-2,cis-9-hexadecadienoyl-CoA 0.0 +r_2243 acyl-CoA oxidase (cis-tetradec-7-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-tetradec-7-enoyl-CoA --> hydrogen peroxide + trans-2,cis-7-tetradecadienoyl-CoA 0.0 +r_2244 acyl-CoA oxidase (cis-dodec-5-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-dodec-5-enoyl-CoA --> hydrogen peroxide + trans-2,cis-5-dodecadienoyl-CoA 0.0 +r_2245 acyl-CoA oxidase (oleoyl-CoA) 2.7176949941792783 prot_P13711 + oleoyl-CoA + oxygen --> hydrogen peroxide + trans-2,cis-9-octadecadienoyl-CoA 0.0 +r_2246 acyl-CoA oxidase (cis-hexadec-7-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-hexadec-7-enoyl-CoA --> hydrogen peroxide + trans-2,cis-7-hexadecadienoyl-CoA 0.0 +r_2247 acyl-CoA oxidase (cis-tetradec-5-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-tetradec-5-enoyl-CoA --> hydrogen peroxide + trans-2,cis-5-tetradecadienoyl-CoA 0.0 +r_2248 2-enoyl-CoA hydratase (3-hydroxydecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dec-2-enoyl-CoA --> (R)-3-hydroxydecanoyl-CoA 0.0 +r_2249 2-enoyl-CoA hydratase (3-hydroxydodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dodec-2-enoyl-CoA --> (R)-3-hydroxylauroyl-CoA 0.0 +r_2250 2-enoyl-CoA hydratase (3-hydroxytetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetradec-2-enoyl-CoA --> (S)-3-hydroxytetradecanoyl-CoA 0.0 r_2251 2-enoyl-CoA hydratase (3-hydroxyhexadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + hexadec-2-enoyl-CoA --> (S)-3-hydroxypalmitoyl-CoA 0.0 r_2252 2-enoyl-CoA hydratase (3-hydroxyoctadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-octadec-2-enoyl-CoA --> 3-hydroxyoctadecanoyl-CoA 0.0 r_2253 2-enoyl-CoA hydratase (3-hydroxyhexacosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hexacos-2-enoyl-CoA --> (S)-3-hydroxyhexacosanoyl-CoA 0.0 -r_2254 2-enoyl-CoA hydratase (3-hydroxybutanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-but-2-enoyl-CoA --> (R)-3-hydroxybutanoyl-CoA 1.9000000606814286e-05 -r_2255 2-enoyl-CoA hydratase (3-hydroxyhexanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hex-2-enoyl-CoA --> (R)-3-hydroxyhexanoyl-CoA 1.9000000606814286e-05 -r_2256 2-enoyl-CoA hydratase (3-hydroxyoctanoyl-CoA) 0.07066365979381443 prot_Q02207 + 4.0 H+ + H2O + trans-oct-2-enoyl-CoA --> (R)-3-hydroxyoctanoyl-CoA 1.9000000606814286e-05 +r_2254 2-enoyl-CoA hydratase (3-hydroxybutanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-but-2-enoyl-CoA --> (R)-3-hydroxybutanoyl-CoA 0.0 +r_2255 2-enoyl-CoA hydratase (3-hydroxyhexanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hex-2-enoyl-CoA --> (R)-3-hydroxyhexanoyl-CoA 0.0 +r_2256 2-enoyl-CoA hydratase (3-hydroxyoctanoyl-CoA) 0.07066365979381443 prot_Q02207 + 4.0 H+ + H2O + trans-oct-2-enoyl-CoA --> (R)-3-hydroxyoctanoyl-CoA 0.0 r_2257 2-enoyl-CoA hydratase (3-hydroxyicosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-icos-2-enoyl-CoA --> (R)-3-hydroxyicosanoyl-CoA 0.0 r_2258 2-enoyl-CoA hydratase (3-hydroxydocosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-docos-2-enoyl-CoA --> (R)-3-hydroxydocosanoyl-CoA 0.0 r_2259 2-enoyl-CoA hydratase (3-hydroxytetracosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetracos-2-enoyl-CoA --> (R)-3-hydroxytetracosanoyl-CoA 0.0 -r_2260 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-9-hexadecadienoyl-CoA --> (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA 1.9000000606814286e-05 -r_2261 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-7-tetradecadienoyl-CoA --> (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA 1.9000000606814286e-05 +r_2260 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-9-hexadecadienoyl-CoA --> (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA 0.0 +r_2261 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-7-tetradecadienoyl-CoA --> (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA 0.0 r_2262 2-enoyl-CoA hydratase (3-hydroxy-cis-dodec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-5-dodecadienoyl-CoA --> (R)-3-hydroxy-cis-dodec-5-enoyl-CoA 0.0 -r_2263 2-enoyl-CoA hydratase (3-hydroxy-cis-octadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + 4.0 H+ + H2O + trans-2,cis-9-octadecadienoyl-CoA --> (R)-3-hydroxy-cis-octadec-9-enoyl-CoA 7.302847455517871e-06 -r_2264 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-7-hexadecadienoyl-CoA --> (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA 7.302847455517871e-06 +r_2263 2-enoyl-CoA hydratase (3-hydroxy-cis-octadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + 4.0 H+ + H2O + trans-2,cis-9-octadecadienoyl-CoA --> (R)-3-hydroxy-cis-octadec-9-enoyl-CoA 0.0 +r_2264 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-7-hexadecadienoyl-CoA --> (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA 0.0 r_2265 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-5-tetradecadienoyl-CoA --> (R)-3-hydroxy-cis-tetradec-5-enoyl-CoA 0.0 -r_2266 3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxydecanoyl-CoA + NAD --> 3-oxodecanoyl-CoA + H+ + NADH 1.9000000606814286e-05 -r_2267 3-hydroxyacyl-CoA dehydrogenase (3-oxododecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxylauroyl-CoA + NAD --> 3-oxolauroyl-CoA + H+ + NADH 1.9000000606814286e-05 +r_2266 3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxydecanoyl-CoA + NAD --> 3-oxodecanoyl-CoA + H+ + NADH 0.0 +r_2267 3-hydroxyacyl-CoA dehydrogenase (3-oxododecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxylauroyl-CoA + NAD --> 3-oxolauroyl-CoA + H+ + NADH 0.0 r_2268 3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxypalmitoyl-CoA + NAD --> 3-oxopalmitoyl-CoA + H+ + NADH 0.0 r_2269 3-hydroxyacyl-CoA dehydrogenase (3-oxooctadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + 3-hydroxyoctadecanoyl-CoA + NAD --> 3-oxooctadecanoyl-CoA + H+ + NADH 0.0 r_2270 3-hydroxyacyl-CoA dehydrogenase (3-oxohexacosanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxyhexacosanoyl-CoA + NAD --> 3-oxohexacosanoyl-CoA + H+ + NADH 0.0 -r_2271 3-hydroxyacyl-CoA dehydrogenase (3-oxobutanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxybutanoyl-CoA --> H+ + NADH + acetoacetyl-CoA 1.9000000606814286e-05 -r_2272 3-hydroxyacyl-CoA dehydrogenase (3-oxohexanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyhexanoyl-CoA --> H+ + NADH + 3-oxohexanoyl-CoA 1.9000000606814286e-05 -r_2273 3-hydroxyacyl-CoA dehydrogenase (3-oxooctanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyoctanoyl-CoA --> H+ + NADH + 3-oxooctanoyl-CoA 1.9000000606814286e-05 +r_2271 3-hydroxyacyl-CoA dehydrogenase (3-oxobutanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxybutanoyl-CoA --> H+ + NADH + acetoacetyl-CoA 0.0 +r_2272 3-hydroxyacyl-CoA dehydrogenase (3-oxohexanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyhexanoyl-CoA --> H+ + NADH + 3-oxohexanoyl-CoA 0.0 +r_2273 3-hydroxyacyl-CoA dehydrogenase (3-oxooctanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyoctanoyl-CoA --> H+ + NADH + 3-oxooctanoyl-CoA 0.0 r_2274 3-hydroxyacyl-CoA dehydrogenase (3-oxoicosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyicosanoyl-CoA --> H+ + NADH + 3-oxoicosanoyl-CoA 0.0 r_2275 3-hydroxyacyl-CoA dehydrogenase (3-oxodocosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxydocosanoyl-CoA --> H+ + NADH + 3-oxodocosanoyl-CoA 0.0 r_2276 3-hydroxyacyl-CoA dehydrogenase (3-oxotetracosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxytetracosanoyl-CoA --> H+ + NADH + 3-oxotetracosanoyl-CoA 0.0 -r_2277 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA --> H+ + NADH + 3-oxo-cis-hexadec-9-enoyl-CoA 1.9000000606814286e-05 -r_2278 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA --> H+ + NADH + 3-oxo-cis-tetradec-7-enoyl-CoA 1.9000000606814286e-05 +r_2277 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA --> H+ + NADH + 3-oxo-cis-hexadec-9-enoyl-CoA 0.0 +r_2278 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA --> H+ + NADH + 3-oxo-cis-tetradec-7-enoyl-CoA 0.0 r_2279 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-dodec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-dodec-5-enoyl-CoA --> H+ + NADH + 3-oxo-cis-dodec-5-enoyl-CoA 0.0 -r_2280 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-octadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-octadec-9-enoyl-CoA --> H+ + NADH + 3-oxo-cis-octadec-9-enoyl-CoA 7.302847455517871e-06 -r_2281 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA --> H+ + NADH + 3-oxo-cis-hexadec-7-enoyl-CoA 7.302847455517871e-06 +r_2280 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-octadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-octadec-9-enoyl-CoA --> H+ + NADH + 3-oxo-cis-octadec-9-enoyl-CoA 0.0 +r_2281 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA --> H+ + NADH + 3-oxo-cis-hexadec-7-enoyl-CoA 0.0 r_2282 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-tetradec-5-enoyl-CoA --> H+ + NADH + 3-oxo-cis-tetradec-5-enoyl-CoA 0.0 -r_2283 acetyl-CoA C-acyltransferase (acetyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + acetoacetyl-CoA --> 2.0 acetyl-CoA 1.9000000606814286e-05 -r_2284 acetyl-CoA C-acyltransferase (butanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxohexanoyl-CoA --> acetyl-CoA + 4.0 H+ + butanoyl-CoA 1.9000000606814286e-05 -r_2285 acetyl-CoA C-acyltransferase (hexanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxooctanoyl-CoA --> acetyl-CoA + hexanoyl-CoA 1.9000000606814286e-05 +r_2283 acetyl-CoA C-acyltransferase (acetyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + acetoacetyl-CoA --> 2.0 acetyl-CoA 0.0 +r_2284 acetyl-CoA C-acyltransferase (butanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxohexanoyl-CoA --> acetyl-CoA + 4.0 H+ + butanoyl-CoA 0.0 +r_2285 acetyl-CoA C-acyltransferase (hexanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxooctanoyl-CoA --> acetyl-CoA + hexanoyl-CoA 0.0 r_2286 acetyl-CoA C-acyltransferase (stearoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxoicosanoyl-CoA --> acetyl-CoA + stearoyl-CoA 0.0 r_2287 acetyl-CoA C-acyltransferase (icosanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxodocosanoyl-CoA --> acetyl-CoA + icosanoyl-CoA 0.0 r_2288 acetyl-CoA C-acyltransferase (docosanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxotetracosanoyl-CoA --> acetyl-CoA + docosanoyl-CoA 0.0 -r_2289 acetyl-CoA C-acyltransferase (cis-tetradec-7-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-hexadec-9-enoyl-CoA --> acetyl-CoA + cis-tetradec-7-enoyl-CoA 1.9000000606814286e-05 -r_2290 acetyl-CoA C-acyltransferase (cis-dodec-5-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-tetradec-7-enoyl-CoA --> acetyl-CoA + cis-dodec-5-enoyl-CoA 1.9000000606814286e-05 +r_2289 acetyl-CoA C-acyltransferase (cis-tetradec-7-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-hexadec-9-enoyl-CoA --> acetyl-CoA + cis-tetradec-7-enoyl-CoA 0.0 +r_2290 acetyl-CoA C-acyltransferase (cis-dodec-5-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-tetradec-7-enoyl-CoA --> acetyl-CoA + cis-dodec-5-enoyl-CoA 0.0 r_2291 acetyl-CoA C-acyltransferase (cis-dec-3-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-dodec-5-enoyl-CoA --> acetyl-CoA + cis-dec-3-enoyl-CoA 0.0 -r_2292 acetyl-CoA C-acyltransferase (cis-hexadec-7-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-octadec-9-enoyl-CoA --> acetyl-CoA + cis-hexadec-7-enoyl-CoA 7.302847455517871e-06 -r_2293 acetyl-CoA C-acyltransferase (cis-tetradec-5-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-hexadec-7-enoyl-CoA --> acetyl-CoA + cis-tetradec-5-enoyl-CoA 7.302847455517871e-06 +r_2292 acetyl-CoA C-acyltransferase (cis-hexadec-7-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-octadec-9-enoyl-CoA --> acetyl-CoA + cis-hexadec-7-enoyl-CoA 0.0 +r_2293 acetyl-CoA C-acyltransferase (cis-tetradec-5-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-hexadec-7-enoyl-CoA --> acetyl-CoA + cis-tetradec-5-enoyl-CoA 0.0 r_2294 acetyl-CoA C-acyltransferase (cis-dodec-3-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-tetradec-5-enoyl-CoA --> acetyl-CoA + cis-dodec-3-enoyl-CoA 0.0 r_2295 delta3,delta2-enoyl-CoA isomerase (cis-dec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + cis-dec-3-enoyl-CoA --> 4.0 H+ + trans-dec-2-enoyl-CoA 0.0 -r_2296 delta3,delta2-enoyl-CoA isomerase (trans-2,cis-5-dodecadienoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-2,cis-5-dodecadienoyl-CoA --> trans-3,cis-5-dodecadienoyl-CoA 1.9000000606814286e-05 -r_2297 delta3,delta2-enoyl-CoA isomerase (trans-dodec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-dodec-3-enoyl-CoA --> 4.0 H+ + trans-dodec-2-enoyl-CoA 1.9000000606814286e-05 +r_2296 delta3,delta2-enoyl-CoA isomerase (trans-2,cis-5-dodecadienoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-2,cis-5-dodecadienoyl-CoA --> trans-3,cis-5-dodecadienoyl-CoA 0.0 +r_2297 delta3,delta2-enoyl-CoA isomerase (trans-dodec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-dodec-3-enoyl-CoA --> 4.0 H+ + trans-dodec-2-enoyl-CoA 0.0 r_2298 delta3,delta2-enoyl-CoA isomerase (cis-dodec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + cis-dodec-3-enoyl-CoA --> 4.0 H+ + trans-dodec-2-enoyl-CoA 0.0 -r_2299 delta3,delta2-enoyl-CoA isomerase (trans-2,cis-5-tetradecadienoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-2,cis-5-tetradecadienoyl-CoA --> trans-3,cis-5-tetradecadienoyl-CoA 7.302847455517871e-06 -r_2300 delta3,delta2-enoyl-CoA isomerase (trans-tetradec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-tetradec-3-enoyl-CoA --> 4.0 H+ + trans-tetradec-2-enoyl-CoA 7.302847455517871e-06 -r_2301 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-dodecadienoyl-CoA) 0.0026092013888888888 prot_Q08558 + trans-3,cis-5-dodecadienoyl-CoA --> trans-2,trans-4-dodecadienoyl-CoA 1.9000000606814286e-05 -r_2302 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-tetradecadienoyl-CoA) 0.0026092013888888888 prot_Q08558 + trans-3,cis-5-tetradecadienoyl-CoA --> trans-2,trans-4-tetradecadienoyl-CoA 7.302847455517871e-06 -r_2303 2,4-dienoyl-CoA reductase (trans-2,trans-4-dodecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-dodecadienoyl-CoA --> NADP(+) + trans-dodec-3-enoyl-CoA 1.9000000606814286e-05 -r_2304 2,4-dienoyl-CoA reductase (trans-2,trans-4-tetradecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-tetradecadienoyl-CoA --> NADP(+) + trans-tetradec-3-enoyl-CoA 7.302847455517871e-06 -r_2305 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 1.269587097829964 +r_2299 delta3,delta2-enoyl-CoA isomerase (trans-2,cis-5-tetradecadienoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-2,cis-5-tetradecadienoyl-CoA --> trans-3,cis-5-tetradecadienoyl-CoA 0.0 +r_2300 delta3,delta2-enoyl-CoA isomerase (trans-tetradec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-tetradec-3-enoyl-CoA --> 4.0 H+ + trans-tetradec-2-enoyl-CoA 0.0 +r_2301 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-dodecadienoyl-CoA) 0.0026092013888888888 prot_Q08558 + trans-3,cis-5-dodecadienoyl-CoA --> trans-2,trans-4-dodecadienoyl-CoA 0.0 +r_2302 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-tetradecadienoyl-CoA) 0.0026092013888888888 prot_Q08558 + trans-3,cis-5-tetradecadienoyl-CoA --> trans-2,trans-4-tetradecadienoyl-CoA 0.0 +r_2303 2,4-dienoyl-CoA reductase (trans-2,trans-4-dodecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-dodecadienoyl-CoA --> NADP(+) + trans-dodec-3-enoyl-CoA 0.0 +r_2304 2,4-dienoyl-CoA reductase (trans-2,trans-4-tetradecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-tetradecadienoyl-CoA --> NADP(+) + trans-tetradec-3-enoyl-CoA 0.0 +r_2305 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 1.260812446021116 r_2305_REV cis-aconitate(3-) to isocitrate (reversible) 0.16582750582750583 prot_P19414 + isocitrate --> cis-aconitate + H2O 0.0 -r_2308_EXP_1 glycerol-3-phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.003153248722094766 +r_2308_EXP_1 glycerol-3-phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0031532487220947655 r_2308_EXP_2 glycerol-3-phosphate acyltransferase (16:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0 -r_2309_EXP_1 glycerol-3-phosphate acyltransferase (16:1), ER membrane 124.56838874829987 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.003083349588722361 +r_2309_EXP_1 glycerol-3-phosphate acyltransferase (16:1), ER membrane 124.56838874829987 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.003083349588722355 r_2309_EXP_2 glycerol-3-phosphate acyltransferase (16:1), ER membrane 121.5898765007065 prot_P36148 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0 -r_2310 glycerol-3-phosphate acyltransferase (18:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + stearoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0006939317486876009 +r_2310 glycerol-3-phosphate acyltransferase (18:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + stearoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0 r_2311 glycerol-3-phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 0.0 r_2312_EXP_1 dihydroxyacetone phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (16:0) 0.0 r_2312_EXP_2 dihydroxyacetone phosphate acyltransferase (16:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + palmitoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (16:0) 0.0 @@ -2768,7 +2768,7 @@ r_2314 dihydroxyacetone phosphate acyltransferase (18:0), ER membrane 97.6248832 r_2315 dihydroxyacetone phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (18:1) 0.0 r_2316 glycerol-3-phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0 r_2317 glycerol-3-phosphate acyltransferase (16:1), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoleoyl-CoA(4-) --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0 -r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + stearoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) -6.04871976524318e-13 +r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + stearoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.000693931748082729 r_2319 glycerol-3-phosphate acyltransferase (18:1), lipid particle 106.58129459734965 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + oleoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 0.0 r_2320 dihydroxyacetone phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + dihydroxyacetone phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + acylglycerone phosphate (16:0) 0.0 r_2321 dihydroxyacetone phosphate acyltransferase (16:1), lipid particle 97.624883286648 prot_P36148 + dihydroxyacetone phosphate + 2.0 H+ + palmitoleoyl-CoA(4-) --> coenzyme A + acylglycerone phosphate (16:1) 0.0 @@ -2782,13 +2782,13 @@ r_2328 acyl dhap reductase (16:0), lipid particle 0.09115 prot_P40471 + H+ + acy r_2329 acyl dhap reductase (16:1), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (16:1) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (16:1) + NADP(+) 0.0 r_2330 acyl dhap reductase (18:0), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (18:0) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (18:0) + NADP(+) 0.0 r_2331 acyl dhap reductase (18:1), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (18:1) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (18:1) + NADP(+) 0.0 -r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-16:1) 0.0004438790033342618 -r_2333_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.002306272984998046 +r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-16:1) 0.001045441520718695 +r_2333_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0017047104676136127 r_2333_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.000403096733762458 -r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 113.27321041547852 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-16:1) 0.003083349588722361 +r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 113.27321041547852 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-16:1) 0.003083349588722355 r_2335_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 r_2335_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 -r_2336 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-16:1) 0.0006939317486876009 +r_2336 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-16:1) 0.0 r_2337_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 r_2337_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 r_2338 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-16:1) 0.0 @@ -2802,7 +2802,7 @@ r_2341_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), li r_2341_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 r_2342_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 r_2342_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 -r_2342_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) -6.04871976524318e-13 +r_2342_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0006939317480827291 r_2343_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2343_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2343_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 @@ -2822,12 +2822,12 @@ r_2356 PA phosphatase (1-18:0, 2-16:1), vacuolar membrane 0.0963012769674609 pro r_2357 PA phosphatase (1-18:0, 2-18:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0 r_2358 PA phosphatase (1-18:1, 2-16:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:1, 2-16:1) --> phosphate + diglyceride (1-18:1, 2-16:1) + 2.0 H+ 0.0 r_2359 PA phosphatase (1-18:1, 2-18:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:1, 2-18:1) --> phosphate + diglyceride (1-18:1, 2-18:1) + 2.0 H+ 0.0 -r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + phosphatidate (1-16:0, 2-16:1) + H2O --> phosphate + diglyceride (1-16:0, 2-16:1) + 2.0 H+ 0.0 -r_2361 PA phosphatase (1-16:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:0, 2-18:1) --> phosphate + diglyceride (1-16:0, 2-18:1) + 2.0 H+ 0.0 -r_2362 PA phosphatase (1-16:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-16:1) --> phosphate + diglyceride (1-16:1, 2-16:1) + 2.0 H+ 0.0 +r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + phosphatidate (1-16:0, 2-16:1) + H2O --> phosphate + diglyceride (1-16:0, 2-16:1) + 2.0 H+ 0.000601562517384425 +r_2361 PA phosphatase (1-16:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:0, 2-18:1) --> phosphate + diglyceride (1-16:0, 2-18:1) + 2.0 H+ 0.002104122087072112 +r_2362 PA phosphatase (1-16:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-16:1) --> phosphate + diglyceride (1-16:1, 2-16:1) + 2.0 H+ 0.0008519053834980219 r_2363 PA phosphatase (1-16:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-18:1) --> phosphate + diglyceride (1-16:1, 2-18:1) + 2.0 H+ 0.0 r_2364 PA phosphatase (1-18:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-16:1) --> phosphate + diglyceride (1-18:0, 2-16:1) + 2.0 H+ 0.0 -r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ -6.04871976524318e-13 +r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0006939317480827291 r_2366 PA phosphatase (1-18:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:1, 2-16:1) --> phosphate + diglyceride (1-18:1, 2-16:1) + 2.0 H+ 0.0 r_2367 PA phosphatase (1-18:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:1, 2-18:1) --> phosphate + diglyceride (1-18:1, 2-18:1) + 2.0 H+ 0.0 r_2368_EXP_1 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:0), ER membrane 67.08130559354814 prot_P25628 + palmitoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-16:0) 0.0 @@ -2862,7 +2862,7 @@ r_2377_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membran r_2377_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 r_2378_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_2378_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 -r_2378_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.000656823164360569 +r_2378_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0007491923956637269 r_2379_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2379_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2379_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 @@ -2886,7 +2886,7 @@ r_2385_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membran r_2385_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 r_2386_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 67.08130559354814 prot_P25628 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 r_2386_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 20.519322196722364 prot_P53629 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 -r_2386_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.00010271298783429586 +r_2386_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.00010271298783429562 r_2387_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 67.08130559354814 prot_P25628 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2387_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 20.519322196722364 prot_P53629 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2387_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 @@ -2951,22 +2951,22 @@ r_2421 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:0), lipid particle 1 r_2422 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-18:1, 2-16:1) --> coenzyme A + triglyceride (1-18:1, 2-16:1, 3-18:0) 0.0 r_2423 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-18:0) 0.0 r_2424 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-18:1) 0.0 -r_2425 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:1) 9.236923130306665e-05 +r_2425 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:1) 0.0 r_2426 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:1) 0.0 r_2427 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:1) 0.0 r_2428 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:0, 2-16:1) --> coenzyme A + triglyceride (1-18:0, 2-16:1, 3-18:1) 0.0 r_2429 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:0, 2-18:1) --> coenzyme A + triglyceride (1-18:0, 2-18:1, 3-18:1) 0.0 r_2430 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:1, 2-16:1) --> coenzyme A + triglyceride (1-18:1, 2-16:1, 3-18:1) 0.0 r_2431 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-18:1) 0.0 -r_2432 CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) 0.0004438790033342618 +r_2432 CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) 0.00044387900333427025 r_2432_REV CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) --> H+ + phosphatidate (1-16:0, 2-16:1) + CTP 0.0 -r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0022314442052243405 +r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.002231444205224333 r_2433_REV CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) --> H+ + phosphatidate (1-16:1, 2-16:1) + CTP 0.0 r_2434 CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) 0.0 r_2434_REV CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) --> H+ + phosphatidate (1-18:0, 2-16:1) + CTP 0.0 -r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.003399616352539276 +r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.0033996163525392663 r_2435_REV CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) --> H+ + phosphatidate (1-18:1, 2-16:1) + CTP 0.0 -r_2436 CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 3.685114303957405e-06 +r_2436 CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 3.6851143039588976e-06 r_2436_REV CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) --> H+ + phosphatidate (1-16:0, 2-18:1) + CTP 0.0 r_2437 CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 0.0 r_2437_REV CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) --> H+ + phosphatidate (1-16:1, 2-18:1) + CTP 0.0 @@ -2976,26 +2976,26 @@ r_2439 CDP-diacylglycerol synthase (1-18:1, 2-18:1), ER membrane 1.6138203786746 r_2439_REV CDP-diacylglycerol synthase (1-18:1, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:1, 2-18:1) --> H+ + phosphatidate (1-18:1, 2-18:1) + CTP 0.0 r_2440 CDP-diacylglycerol synthase (1-16:0, 2-16:1), mitochondrial membrane 1.6138203786746388 prot_P38221 + phosphatidate (1-16:0, 2-16:1) + CTP + H+ --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) 0.0 r_2440_REV CDP-diacylglycerol synthase (1-16:0, 2-16:1), mitochondrial membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) + CTP + H+ 0.0 -r_2441 CDP-diacylglycerol synthase (1-16:1, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0008519053834980207 +r_2441 CDP-diacylglycerol synthase (1-16:1, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0 r_2441_REV CDP-diacylglycerol synthase (1-16:1, 2-16:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) --> CTP + H+ + phosphatidate (1-16:1, 2-16:1) 0.0 -r_2442 CDP-diacylglycerol synthase (1-18:0, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-18:0, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) 0.06143413650147051 +r_2442 CDP-diacylglycerol synthase (1-18:0, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-18:0, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) 0.0 r_2442_REV CDP-diacylglycerol synthase (1-18:0, 2-16:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) --> CTP + H+ + phosphatidate (1-18:0, 2-16:1) 0.0 r_2443 CDP-diacylglycerol synthase (1-18:1, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-18:1, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.0 r_2443_REV CDP-diacylglycerol synthase (1-18:1, 2-16:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) --> CTP + H+ + phosphatidate (1-18:1, 2-16:1) 0.0 -r_2444 CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:0, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0027056846044565467 +r_2444 CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:0, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0 r_2444_REV CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) --> CTP + H+ + phosphatidate (1-16:0, 2-18:1) 0.0 r_2445 CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 0.0 r_2445_REV CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) --> CTP + H+ + phosphatidate (1-16:1, 2-18:1) 0.0 -r_2446 PS synthase (1-16:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0004438790033342618 -r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0013751625118413938 +r_2446 PS synthase (1-16:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-16:1) 0.00044387900333427025 +r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0013751625118413853 r_2448 PS synthase (1-18:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-16:1) 0.003399616352539276 -r_2450 PS synthase (1-16:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-18:1) 3.685114303957405e-06 +r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0033996163525392663 +r_2450 PS synthase (1-16:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-18:1) 3.6851143039589006e-06 r_2451 PS synthase (1-16:1, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-18:1) 0.0 r_2452 PS synthase (1-18:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-18:1) 0.0 r_2453 PS synthase (1-18:1, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-18:1) 0.0 r_2454 PI synthase (1-16:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:0, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) 0.0 -r_2455 PI synthase (1-16:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) 0.0008562816933829467 +r_2455 PI synthase (1-16:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) 0.0008562816933829475 r_2456 PI synthase (1-18:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:0, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 0.0 r_2457 PI synthase (1-18:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 r_2458 PI synthase (1-16:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0 @@ -3009,8 +3009,8 @@ r_2463_REV lysoPI acyltransferase (1-18:0, 2-18:1), ER membrane (reversible) 77. r_2464 PS decarboxylase (1-16:0, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-16:1) 0.0 r_2465 PS decarboxylase (1-16:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-16:1) 0.0010072557503258324 r_2466 PS decarboxylase (1-18:0, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_2467 PS decarboxylase (1-18:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.003399616352539276 -r_2468 PS decarboxylase (1-16:0, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-18:1) 3.685114303957405e-06 +r_2467 PS decarboxylase (1-18:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.0033996163525392663 +r_2468 PS decarboxylase (1-16:0, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-18:1) 3.6851143039589006e-06 r_2469 PS decarboxylase (1-16:1, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:1, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2470 PS decarboxylase (1-18:0, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 r_2471 PS decarboxylase (1-18:1, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:1, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 @@ -3033,30 +3033,30 @@ r_2487 PS decarboxylase (1-18:1, 2-18:1), vacuolar membrane 0.09853409090909093 r_2488 PE methyltransferase (1-16:0, 2-16:1), ER membrane 1627.5240996397504 prot_P05374 + phosphatidylethanolamine (1-16:0, 2-16:1) + S-adenosyl-L-methionine --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) 0.0 r_2489 PE methyltransferase (1-16:1, 2-16:1), ER membrane 1772.794398518638 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) 0.0 r_2490 PE methyltransferase (1-18:0, 2-16:1), ER membrane 2311.996703472735 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) 0.0 -r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 169.40036397185034 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) 0.003399616352539276 -r_2492 PE methyltransferase (1-16:0, 2-18:1), ER membrane 1187.9768182494734 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) 3.685114303957405e-06 +r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 169.40036397185034 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) 0.0033996163525392663 +r_2492 PE methyltransferase (1-16:0, 2-18:1), ER membrane 1187.9768182494734 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) 3.6851143039589006e-06 r_2493 PE methyltransferase (1-16:1, 2-18:1), ER membrane 1927.895637345238 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) 0.0 r_2494 PE methyltransferase (1-18:0, 2-18:1), ER membrane 1845.2830881909267 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) 0.0 r_2495 PE methyltransferase (1-18:1, 2-18:1), ER membrane 1146.7320397250028 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-18:1) 0.0 r_2496 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) 0.0 r_2497 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) 0.0 r_2498 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) 0.0 -r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) 0.003399616352539276 -r_2500 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) 3.685114303957429e-06 +r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) 0.0033996163525392663 +r_2500 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) 3.6851143039588925e-06 r_2501 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) 0.0 r_2502 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) 0.0 r_2503 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-18:1) 0.0 r_2504 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2505 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2506 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:0, 2-16:1) 0.0 -r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-16:1) 0.003399616352539276 -r_2508 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-18:1) 3.685114303957429e-06 +r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-16:1) 0.0033996163525392663 +r_2508 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-18:1) 3.6851143039588925e-06 r_2509 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2510 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2511 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_2512 DAG kinase (1-16:0, 2-16:1), ER membrane 38.37566351210669 prot_Q12382 + H+ + diglyceride (1-16:0, 2-16:1) + CTP --> phosphatidate (1-16:0, 2-16:1) + CDP 0.0 r_2513 DAG kinase (1-16:1, 2-16:1), ER membrane 38.37566351210669 prot_Q12382 + H+ + diglyceride (1-16:1, 2-16:1) + CTP --> phosphatidate (1-16:1, 2-16:1) + CDP 0.0 -r_2514 DAG kinase (1-18:0, 2-16:1), ER membrane 38.37566351210669 prot_Q12382 + H+ + diglyceride (1-18:0, 2-16:1) + CTP --> phosphatidate (1-18:0, 2-16:1) + CDP 0.06074020475278291 +r_2514 DAG kinase (1-18:0, 2-16:1), ER membrane 38.37566351210669 prot_Q12382 + H+ + diglyceride (1-18:0, 2-16:1) + CTP --> phosphatidate (1-18:0, 2-16:1) + CDP 0.0 r_2515 DAG kinase (1-18:1, 2-16:1), ER membrane 38.37566351210669 prot_Q12382 + H+ + diglyceride (1-18:1, 2-16:1) + CTP --> phosphatidate (1-18:1, 2-16:1) + CDP 0.0 r_2516 DAG kinase (1-16:0, 2-18:1), ER membrane 38.37566351210669 prot_Q12382 + H+ + diglyceride (1-16:0, 2-18:1) + CTP --> phosphatidate (1-16:0, 2-18:1) + CDP 0.0 r_2517 DAG kinase (1-16:1, 2-18:1), ER membrane 38.37566351210669 prot_Q12382 + H+ + diglyceride (1-16:1, 2-18:1) + CTP --> phosphatidate (1-16:1, 2-18:1) + CDP 0.0 @@ -3070,33 +3070,33 @@ r_2524 ethanolaminephosphotransferase (1-16:0, 2-18:1), ER membrane 12.259319894 r_2525 ethanolaminephosphotransferase (1-16:1, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2526 ethanolaminephosphotransferase (1-18:0, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 r_2527 ethanolaminephosphotransferase (1-18:1, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-18:1, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 -r_2528_EXP_1 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.0 +r_2528_EXP_1 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.000601562517384425 r_2528_EXP_2 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2529_EXP_1 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2529_EXP_2 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-16:1) 0.0 -r_2530_EXP_1 cholinephosphotransferase (1-18:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-16:1) 0.0006939317486876009 +r_2530_EXP_1 cholinephosphotransferase (1-18:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_2530_EXP_2 cholinephosphotransferase (1-18:0, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_2531_EXP_1 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2531_EXP_2 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-16:1) 0.0 -r_2532_EXP_1 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0027056846044565467 +r_2532_EXP_1 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.002104122087072112 r_2532_EXP_2 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_2533_EXP_1 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2533_EXP_2 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0 -r_2534_EXP_1 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) -6.04871976524318e-13 +r_2534_EXP_1 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0006939317480827291 r_2534_EXP_2 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2535_EXP_1 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_2535_EXP_2 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_2536 phosphatidylglycerolphosphate synthase (1-16:0, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:0, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-16:1) 0.0 -r_2537 phosphatidylglycerolphosphate synthase (1-16:1, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) 0.0008519053834980207 -r_2538 phosphatidylglycerolphosphate synthase (1-18:0, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-18:0, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:0, 2-16:1) 0.06143413650147051 +r_2537 phosphatidylglycerolphosphate synthase (1-16:1, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) 0.0 +r_2538 phosphatidylglycerolphosphate synthase (1-18:0, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-18:0, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:0, 2-16:1) 0.0 r_2539 phosphatidylglycerolphosphate synthase (1-18:1, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-18:1, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:1, 2-16:1) 0.0 -r_2540 phosphatidylglycerolphosphate synthase (1-16:0, 2-18:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:0, 2-18:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-18:1) 0.0027056846044565467 +r_2540 phosphatidylglycerolphosphate synthase (1-16:0, 2-18:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:0, 2-18:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-18:1) 0.0 r_2541 phosphatidylglycerolphosphate synthase (1-16:1, 2-18:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-18:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) 0.0 r_2542 PGP phosphatase (1-16:0, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-16:1) + H2O --> 2.0 H+ + phosphatidylglycerol (1-16:0, 2-16:1) + phosphate 0.0 -r_2543 PGP phosphatase (1-16:1, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-16:1) 0.0008519053834980207 -r_2544 PGP phosphatase (1-18:0, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:0, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-18:0, 2-16:1) 0.06143413650147051 +r_2543 PGP phosphatase (1-16:1, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-16:1) 0.0 +r_2544 PGP phosphatase (1-18:0, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:0, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-18:0, 2-16:1) 0.0 r_2545 PGP phosphatase (1-18:1, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:1, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-18:1, 2-16:1) 0.0 -r_2546 PGP phosphatase (1-16:0, 2-18:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-18:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:0, 2-18:1) 0.0027056846044565467 +r_2546 PGP phosphatase (1-16:0, 2-18:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-18:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:0, 2-18:1) 0.0 r_2547 PGP phosphatase (1-16:1, 2-18:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-18:1) 0.0 r_2548 CL synthase (1-16:0, 2-16:1, 3-16:0, 4-16:1), mitochondrial membrane 4334.5245830625945 prot_Q07560 + CDP-diacylglycerol (1-16:0, 2-16:1) + phosphatidylglycerol (1-16:0, 2-16:1) --> 2.0 H+ + CMP + cardiolipin (1-16:0, 2-16:1, 3-16:0, 4-16:1) 0.0 r_2549 CL synthase (1-16:0, 2-16:1, 3-16:1, 4-16:1), mitochondrial membrane 4334.5245830625945 prot_Q07560 + CDP-diacylglycerol (1-16:0, 2-16:1) + phosphatidylglycerol (1-16:1, 2-16:1) --> 2.0 H+ + CMP + cardiolipin (1-16:0, 2-16:1, 3-16:1, 4-16:1) 0.0 @@ -3798,7 +3798,7 @@ r_2956 PC (1-16:0, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER m r_2956_REV PC (1-16:0, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane (reversible) 5093.1236446912435 prot_P40345 + triglyceride (1-16:1, 2-16:1, 3-16:1) + 1-acylglycerophosphocholine (16:0) --> diglyceride (1-16:1, 2-16:1) + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2957 PC (1-16:1, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 5093.1236446912435 prot_P40345 + diglyceride (1-16:1, 2-16:1) + phosphatidylcholine (1-16:1, 2-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) + 1-acylglycerophosphocholine (16:1) 0.0 r_2957_REV PC (1-16:1, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane (reversible) 5093.1236446912435 prot_P40345 + triglyceride (1-16:1, 2-16:1, 3-16:1) + 1-acylglycerophosphocholine (16:1) --> diglyceride (1-16:1, 2-16:1) + phosphatidylcholine (1-16:1, 2-16:1) 0.0 -r_2958 PC (1-18:0, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 5093.1236446912435 prot_P40345 + diglyceride (1-16:1, 2-16:1) + phosphatidylcholine (1-18:0, 2-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) + 1-acylglycerophosphocholine (18:0) 9.236923130306665e-05 +r_2958 PC (1-18:0, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 5093.1236446912435 prot_P40345 + diglyceride (1-16:1, 2-16:1) + phosphatidylcholine (1-18:0, 2-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) + 1-acylglycerophosphocholine (18:0) 0.0 r_2958_REV PC (1-18:0, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane (reversible) 5093.1236446912435 prot_P40345 + triglyceride (1-16:1, 2-16:1, 3-16:1) + 1-acylglycerophosphocholine (18:0) --> diglyceride (1-16:1, 2-16:1) + phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_2959 PC (1-18:1, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane 5093.1236446912435 prot_P40345 + diglyceride (1-16:1, 2-16:1) + phosphatidylcholine (1-18:1, 2-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2959_REV PC (1-18:1, 2-16:1) diacylglycerol (1-16:1, 2-16:1) acyltransferase, ER membrane (reversible) 5093.1236446912435 prot_P40345 + triglyceride (1-16:1, 2-16:1, 3-16:1) + 1-acylglycerophosphocholine (18:1) --> diglyceride (1-16:1, 2-16:1) + phosphatidylcholine (1-18:1, 2-16:1) 0.0 @@ -3855,7 +3855,7 @@ r_2984_REV PC (1-16:0, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, r_2985 PC (1-16:1, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane 5093.1236446912435 prot_P40345 + diglyceride (1-16:0, 2-18:1) + phosphatidylcholine (1-16:1, 2-18:1) --> triglyceride (1-16:0, 2-18:1, 3-18:1) + 1-acylglycerophosphocholine (16:1) 0.0 r_2985_REV PC (1-16:1, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane (reversible) 5093.1236446912435 prot_P40345 + triglyceride (1-16:0, 2-18:1, 3-18:1) + 1-acylglycerophosphocholine (16:1) --> diglyceride (1-16:0, 2-18:1) + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2986 PC (1-18:0, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane 5093.1236446912435 prot_P40345 + diglyceride (1-16:0, 2-18:1) + phosphatidylcholine (1-18:0, 2-18:1) --> triglyceride (1-16:0, 2-18:1, 3-18:1) + 1-acylglycerophosphocholine (18:0) 0.0 -r_2986_REV PC (1-18:0, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane (reversible) 5093.1236446912435 prot_P40345 + triglyceride (1-16:0, 2-18:1, 3-18:1) + 1-acylglycerophosphocholine (18:0) --> diglyceride (1-16:0, 2-18:1) + phosphatidylcholine (1-18:0, 2-18:1) 9.236923130306665e-05 +r_2986_REV PC (1-18:0, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane (reversible) 5093.1236446912435 prot_P40345 + triglyceride (1-16:0, 2-18:1, 3-18:1) + 1-acylglycerophosphocholine (18:0) --> diglyceride (1-16:0, 2-18:1) + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2987 PC (1-18:1, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane 5093.1236446912435 prot_P40345 + diglyceride (1-16:0, 2-18:1) + phosphatidylcholine (1-18:1, 2-18:1) --> triglyceride (1-16:0, 2-18:1, 3-18:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2987_REV PC (1-18:1, 2-18:1) diacylglycerol (1-16:0, 2-18:1) acyltransferase, ER membrane (reversible) 5093.1236446912435 prot_P40345 + triglyceride (1-16:0, 2-18:1, 3-18:1) + 1-acylglycerophosphocholine (18:1) --> diglyceride (1-16:0, 2-18:1) + phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_2988 PC (1-16:0, 2-16:1) diacylglycerol (1-16:1, 2-18:1) acyltransferase, ER membrane 5093.1236446912435 prot_P40345 + diglyceride (1-16:1, 2-18:1) + phosphatidylcholine (1-16:0, 2-16:1) --> triglyceride (1-16:1, 2-18:1, 3-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 @@ -4007,15 +4007,15 @@ r_3095 PI 4,5-P2 phospholipase C (1-16:1, 2-18:1), nucleus 0.0321987491713981 pr r_3096 PI 4,5-P2 phospholipase C (1-18:0, 2-18:1), nucleus 0.0321987491713981 prot_P32383 + H2O + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) --> 1D-myo-inositol 1,4,5-trisphosphate + 6.0 H+ + diglyceride (1-18:0, 2-18:1) 0.0 r_3097 PI 4,5-P2 phospholipase C (1-18:1, 2-18:1), nucleus 0.0321987491713981 prot_P32383 + H2O + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) --> 1D-myo-inositol 1,4,5-trisphosphate + 6.0 H+ + diglyceride (1-18:1, 2-18:1) 0.0 r_3098 PG phospholipase C (1-16:0, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:0, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:0, 2-16:1) 0.0 -r_3099 PG phospholipase C (1-16:1, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-16:1) 0.0008519053834980207 -r_3100 PG phospholipase C (1-18:0, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-18:0, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-18:0, 2-16:1) 0.06143413650147051 +r_3099 PG phospholipase C (1-16:1, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-16:1) 0.0 +r_3100 PG phospholipase C (1-18:0, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-18:0, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-18:0, 2-16:1) 0.0 r_3101 PG phospholipase C (1-18:1, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-18:1, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-18:1, 2-16:1) 0.0 -r_3102 PG phospholipase C (1-16:0, 2-18:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:0, 2-18:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:0, 2-18:1) 0.0027056846044565467 +r_3102 PG phospholipase C (1-16:0, 2-18:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:0, 2-18:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:0, 2-18:1) 0.0 r_3103 PG phospholipase C (1-16:1, 2-18:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-18:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-18:1) 0.0 r_3104 PC phospholipase D (1-16:0, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + phosphatidylcholine (1-16:0, 2-16:1) + H2O --> choline + phosphatidate (1-16:0, 2-16:1) 0.0 r_3105 PC phospholipase D (1-16:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-16:1) --> choline + phosphatidate (1-16:1, 2-16:1) 0.0 r_3106 PC phospholipase D (1-18:0, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:0, 2-16:1) --> choline + phosphatidate (1-18:0, 2-16:1) 0.0 -r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:1, 2-16:1) --> choline + phosphatidate (1-18:1, 2-16:1) 0.003399616352539276 +r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:1, 2-16:1) --> choline + phosphatidate (1-18:1, 2-16:1) 0.0033996163525392663 r_3108 PC phospholipase D (1-16:0, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:0, 2-18:1) --> choline + phosphatidate (1-16:0, 2-18:1) 0.0 r_3109 PC phospholipase D (1-16:1, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-18:1) --> choline + phosphatidate (1-16:1, 2-18:1) 0.0 r_3110 PC phospholipase D (1-18:0, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:0, 2-18:1) --> choline + phosphatidate (1-18:0, 2-18:1) 0.0 @@ -4620,32 +4620,32 @@ r_3504 IPC synthase (PI (1-16:0, 2-18:1) ceramide-4 (C26)) 142.7071089252805 pro r_3505 IPC synthase (PI (1-16:1, 2-18:1) ceramide-4 (C26)) 142.7071089252805 prot_P36107 + 80.47148814754162 prot_Q06346 + ceramide-4 (C26) + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> inositol-P-ceramide D (C26) + diglyceride (1-16:1, 2-18:1) 0.0 r_3506 IPC synthase (PI (1-18:0, 2-18:1) ceramide-4 (C26)) 142.7071089252805 prot_P36107 + 80.47148814754162 prot_Q06346 + ceramide-4 (C26) + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> inositol-P-ceramide D (C26) + diglyceride (1-18:0, 2-18:1) 0.0 r_3507 IPC synthase (PI (1-18:1, 2-18:1) ceramide-4 (C26)) 142.7071089252805 prot_P36107 + 80.47148814754162 prot_Q06346 + ceramide-4 (C26) + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> inositol-P-ceramide D (C26) + diglyceride (1-18:1, 2-18:1) 0.0 -r_3508 laurate transport, cytoplasm-ER membrane laurate --> laurate 7.302847455517871e-06 +r_3508 laurate transport, cytoplasm-ER membrane laurate --> laurate 0.0 r_3508_REV laurate transport, cytoplasm-ER membrane (reversible) laurate --> laurate 0.0 r_3509 myristate transport, cytoplasm-ER membrane myristate --> myristate 0.0 r_3509_REV myristate transport, cytoplasm-ER membrane (reversible) myristate --> myristate 0.0 r_3510 palmitate transport, cytoplasm-ER membrane palmitate --> palmitate 0.0 r_3510_REV palmitate transport, cytoplasm-ER membrane (reversible) palmitate --> palmitate 0.0 r_3511 palmitoleate transport, cytoplasm-ER membrane palmitoleate --> palmitoleate 0.0 -r_3511_REV palmitoleate transport, cytoplasm-ER membrane (reversible) palmitoleate --> palmitoleate 0.0 +r_3511_REV palmitoleate transport, cytoplasm-ER membrane (reversible) palmitoleate --> palmitoleate 0.0005840846230801189 r_3512 stearate transport, cytoplasm-ER membrane stearate --> stearate 0.0 r_3512_REV stearate transport, cytoplasm-ER membrane (reversible) stearate --> stearate 0.0 r_3513 oleate transport, cytoplasm-ER membrane oleate --> oleate 0.0 r_3513_REV oleate transport, cytoplasm-ER membrane (reversible) oleate --> oleate 0.0 -r_3514 malonyl-CoA transport, cytoplasm-ER membrane malonyl-CoA --> malonyl-CoA 0.0039009119209434673 +r_3514 malonyl-CoA transport, cytoplasm-ER membrane malonyl-CoA --> malonyl-CoA 0.003879003378576912 r_3514_REV malonyl-CoA transport, cytoplasm-ER membrane (reversible) malonyl-CoA --> malonyl-CoA 0.0 r_3515 lauroyl-CoA transport, cytoplasm-ER membrane lauroyl-CoA --> lauroyl-CoA 0.0 r_3515_REV lauroyl-CoA transport, cytoplasm-ER membrane (reversible) lauroyl-CoA --> lauroyl-CoA 0.0 r_3516 myristoyl-CoA transport, cytoplasm-ER membrane myristoyl-CoA --> myristoyl-CoA 0.0 r_3516_REV myristoyl-CoA transport, cytoplasm-ER membrane (reversible) myristoyl-CoA --> myristoyl-CoA 0.0 -r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane palmitoyl-CoA --> palmitoyl-CoA 0.01637868784444658 +r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane palmitoyl-CoA --> palmitoyl-CoA 0.016359687843839763 r_3517_REV palmitoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3518 palmitoleoyl-CoA transport, cytoplasm-ER membrane palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 -r_3518_REV palmitoleoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0006030846236869334 +r_3518_REV palmitoleoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3519 stearoyl-CoA transport, cytoplasm-ER membrane stearoyl-CoA --> stearoyl-CoA 0.0 -r_3519_REV stearoyl-CoA transport, cytoplasm-ER membrane (reversible) stearoyl-CoA --> stearoyl-CoA -6.04871976524318e-13 +r_3519_REV stearoyl-CoA transport, cytoplasm-ER membrane (reversible) stearoyl-CoA --> stearoyl-CoA 0.0006939317480827291 r_3520 oleoyl-CoA transport, cytoplasm-ER membrane oleoyl-CoA --> oleoyl-CoA 0.0 -r_3520_REV oleoyl-CoA transport, cytoplasm-ER membrane (reversible) oleoyl-CoA --> oleoyl-CoA 9.967207815371254e-05 +r_3520_REV oleoyl-CoA transport, cytoplasm-ER membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.0006939317480827291 r_3521 icosanoyl-CoA transport, cytoplasm-ER membrane icosanoyl-CoA --> icosanoyl-CoA 0.0 r_3521_REV icosanoyl-CoA transport, cytoplasm-ER membrane (reversible) icosanoyl-CoA --> icosanoyl-CoA 0.0 r_3522 docosanoyl-CoA transport, cytoplasm-ER membrane docosanoyl-CoA --> docosanoyl-CoA 0.0 @@ -4654,56 +4654,56 @@ r_3523 tetracosanoyl-CoA transport, cytoplasm-ER membrane tetracosanoyl-CoA --> r_3523_REV tetracosanoyl-CoA transport, cytoplasm-ER membrane (reversible) tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 r_3524 hexacosanoyl-CoA transport, cytoplasm-ER membrane hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_3524_REV hexacosanoyl-CoA transport, cytoplasm-ER membrane (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 -r_3525 H+ transport, cytoplasm-ER membrane H+ --> H+ 0.06787809040689645 +r_3525 H+ transport, cytoplasm-ER membrane H+ --> H+ 0.007045857178956623 r_3525_REV H+ transport, cytoplasm-ER membrane (reversible) H+ --> H+ 0.0 r_3526_EXP_1 H2O transport, cytoplasm-ER membrane 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_3526_EXP_2 H2O transport, cytoplasm-ER membrane 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_3526_REV_EXP_1 H2O transport, cytoplasm-ER membrane (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.028773106388724087 +r_3526_REV_EXP_1 H2O transport, cytoplasm-ER membrane (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.028698592150232863 r_3526_REV_EXP_2 H2O transport, cytoplasm-ER membrane (reversible) 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_3527 CO2 transport, cytoplasm-ER membrane carbon dioxide --> carbon dioxide 0.0 -r_3527_REV CO2 transport, cytoplasm-ER membrane (reversible) carbon dioxide --> carbon dioxide 0.0039009119209434734 +r_3527_REV CO2 transport, cytoplasm-ER membrane (reversible) carbon dioxide --> carbon dioxide 0.0038790033785769183 r_3528 coenzyme A transport, cytoplasm-ER membrane coenzyme A --> coenzyme A 0.0 -r_3528_REV coenzyme A transport, cytoplasm-ER membrane (reversible) coenzyme A --> coenzyme A 0.01957684306416014 -r_3529 NADPH transport, cytoplasm-ER membrane NADPH --> NADPH 0.007801823841886947 +r_3528_REV coenzyme A transport, cytoplasm-ER membrane (reversible) coenzyme A --> coenzyme A 0.018850827726251223 +r_3529 NADPH transport, cytoplasm-ER membrane NADPH --> NADPH 0.007758006757153837 r_3529_REV NADPH transport, cytoplasm-ER membrane (reversible) NADPH --> NADPH 0.0 r_3530 NADP(+) transport, cytoplasm-ER membrane NADP(+) --> NADP(+) 0.0 -r_3530_REV NADP(+) transport, cytoplasm-ER membrane (reversible) NADP(+) --> NADP(+) 0.007801823841886947 -r_3531 O2 transport, cytoplasm-ER membrane oxygen --> oxygen 0.012436097233890308 +r_3530_REV NADP(+) transport, cytoplasm-ER membrane (reversible) NADP(+) --> NADP(+) 0.007758006757153837 +r_3531 O2 transport, cytoplasm-ER membrane oxygen --> oxygen 0.012409794385827972 r_3531_REV O2 transport, cytoplasm-ER membrane (reversible) oxygen --> oxygen 0.0 -r_3532 NADH transport, cytoplasm-ER membrane NADH --> NADH 0.023609959265826402 +r_3532 NADH transport, cytoplasm-ER membrane NADH --> NADH 0.023583656417759006 r_3532_REV NADH transport, cytoplasm-ER membrane (reversible) NADH --> NADH 0.0 r_3533 NAD transport, cytoplasm-ER membrane NAD --> NAD 0.0 -r_3533_REV NAD transport, cytoplasm-ER membrane (reversible) NAD --> NAD 0.023609959265826402 -r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.006930530059504728 +r_3533_REV NAD transport, cytoplasm-ER membrane (reversible) NAD --> NAD 0.023583656417759006 +r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.006236598310817121 r_3534_REV glycerol 3-phosphate transport, cytoplasm-ER membrane (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3535 dihydroxyacetone phosphate transport, cytoplasm-ER membrane dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3535_REV dihydroxyacetone phosphate transport, cytoplasm-ER membrane (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3536 diphosphate transport, cytoplasm-ER membrane diphosphate --> diphosphate 0.0 -r_3536_REV diphosphate transport, cytoplasm-ER membrane (reversible) diphosphate --> diphosphate 0.006085927522857353 +r_3536_REV diphosphate transport, cytoplasm-ER membrane (reversible) diphosphate --> diphosphate 0.00549454005232171 r_3537 phosphate transport, cytoplasm-ER membrane phosphate --> phosphate 0.0 r_3537_REV phosphate transport, cytoplasm-ER membrane (reversible) phosphate --> phosphate 0.0 -r_3538 CTP transport, cytoplasm-ER membrane CTP --> CTP 0.0668188294281847 +r_3538 CTP transport, cytoplasm-ER membrane CTP --> CTP 0.006078624675401828 r_3538_REV CTP transport, cytoplasm-ER membrane (reversible) CTP --> CTP 0.0 r_3539 CDP transport, cytoplasm-ER membrane CDP --> CDP 0.0 -r_3539_REV CDP transport, cytoplasm-ER membrane (reversible) CDP --> CDP 0.06074020475278291 +r_3539_REV CDP transport, cytoplasm-ER membrane (reversible) CDP --> CDP 0.0 r_3540 CMP transport, cytoplasm-ER membrane CMP --> CMP 0.0 -r_3540_REV CMP transport, cytoplasm-ER membrane (reversible) CMP --> CMP 0.009478241027941066 +r_3540_REV CMP transport, cytoplasm-ER membrane (reversible) CMP --> CMP 0.009478241027941092 r_3541 CDP-ethanolamine transport, cytoplasm-ER membrane CDP-ethanolamine --> CDP-ethanolamine 0.0 r_3541_REV CDP-ethanolamine transport, cytoplasm-ER membrane (reversible) CDP-ethanolamine --> CDP-ethanolamine 0.0 -r_3542 CDP-choline transport, cytoplasm-ER membrane CDP-choline --> CDP-choline 0.003399616352539276 +r_3542 CDP-choline transport, cytoplasm-ER membrane CDP-choline --> CDP-choline 0.0033996163525392663 r_3542_REV CDP-choline transport, cytoplasm-ER membrane (reversible) CDP-choline --> CDP-choline 0.0 -r_3543 ATP transport, cytoplasm-ER membrane ATP --> ATP 7.302847455517871e-06 -r_3543_REV ATP transport, cytoplasm-ER membrane (reversible) ATP --> ATP 0.0 -r_3544 AMP transport, cytoplasm-ER membrane AMP --> AMP 0.0 -r_3544_REV AMP transport, cytoplasm-ER membrane (reversible) AMP --> AMP 7.302847455517871e-06 -r_3545 L-serine transport, cytoplasm-ER membrane 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.005222342982018888 +r_3543 ATP transport, cytoplasm-ER membrane ATP --> ATP 0.0 +r_3543_REV ATP transport, cytoplasm-ER membrane (reversible) ATP --> ATP 0.0005840846230801189 +r_3544 AMP transport, cytoplasm-ER membrane AMP --> AMP 0.0005840846230801189 +r_3544_REV AMP transport, cytoplasm-ER membrane (reversible) AMP --> AMP 0.0 +r_3545 L-serine transport, cytoplasm-ER membrane 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.005222342982018881 r_3545_REV L-serine transport, cytoplasm-ER membrane (reversible) 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.0 -r_3546 myo-inositol transport, cytoplasm-ER membrane myo-inositol --> myo-inositol 0.0008562816933829467 +r_3546 myo-inositol transport, cytoplasm-ER membrane myo-inositol --> myo-inositol 0.0008562816933829475 r_3546_REV myo-inositol transport, cytoplasm-ER membrane (reversible) myo-inositol --> myo-inositol 0.0 -r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.010209904400529688 +r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.010209904400529674 r_3547_REV S-adenosyl-L-methionine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.0 r_3548 S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.0 -r_3548_REV S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.010209904400529685 +r_3548_REV S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.010209904400529674 r_3549 episterol transport, cytoplasm-ER membrane episterol --> episterol 0.0 r_3549_REV episterol transport, cytoplasm-ER membrane (reversible) episterol --> episterol 0.0 r_3550 fecosterol transport, cytoplasm-ER membrane fecosterol --> fecosterol 0.0 @@ -4716,13 +4716,13 @@ r_3553 zymosterol transport, cytoplasm-ER membrane zymosterol --> zymosterol 0.0 r_3553_REV zymosterol transport, cytoplasm-ER membrane (reversible) zymosterol --> zymosterol 0.0 r_3554 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3554_REV diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3555 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0008519053834980207 +r_3555 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3555_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 -r_3556 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.06143413650147051 +r_3556 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3556_REV diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3557 diglyceride (1-18:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3557_REV diglyceride (1-18:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 -r_3558 diglyceride (1-16:0, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.00261331537315348 +r_3558 diglyceride (1-16:0, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3558_REV diglyceride (1-16:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3559 diglyceride (1-16:1, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3559_REV diglyceride (1-16:1, 2-18:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 @@ -4751,24 +4751,24 @@ r_3570_REV sn-glycero-3-phosphocholine transport, ER membrane-cytoplasm (reversi r_3571 hexadecanoate (n-C16:0) transport, cytoplasm-lipid particle palmitate --> palmitate 0.0 r_3571_REV hexadecanoate (n-C16:0) transport, cytoplasm-lipid particle (reversible) palmitate --> palmitate 0.0 r_3572 hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle palmitoleate --> palmitoleate 0.0 -r_3572_REV hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle (reversible) palmitoleate --> palmitoleate 0.0006030846236869334 +r_3572_REV hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle (reversible) palmitoleate --> palmitoleate 0.0 r_3573 octadecanoate (n-C18:0) transport, cytoplasm-lipid particle stearate --> stearate 0.0 r_3573_REV octadecanoate (n-C18:0) transport, cytoplasm-lipid particle (reversible) stearate --> stearate 0.0 r_3574 octadecenoate (n-C18:1) transport, cytoplasm-lipid particle oleate --> oleate 0.0 -r_3574_REV octadecenoate (n-C18:1) transport, cytoplasm-lipid particle (reversible) oleate --> oleate 7.302847455517871e-06 +r_3574_REV octadecenoate (n-C18:1) transport, cytoplasm-lipid particle (reversible) oleate --> oleate 0.0 r_3575 lauroyl-CoA transport, cytoplasm-lipid particle lauroyl-CoA --> lauroyl-CoA 0.0 r_3575_REV lauroyl-CoA transport, cytoplasm-lipid particle (reversible) lauroyl-CoA --> lauroyl-CoA 0.0 r_3576 myristoyl-CoA transport, cytoplasm-lipid particle myristoyl-CoA --> myristoyl-CoA 0.0 r_3576_REV myristoyl-CoA transport, cytoplasm-lipid particle (reversible) myristoyl-CoA --> myristoyl-CoA 0.0 r_3577 palmitoyl-CoA transport, cytoplasm-lipid particle palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3577_REV palmitoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 -r_3578 palmitoleoyl-CoA transport, cytoplasm-lipid particle palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0006030846236869334 -r_3578_REV palmitoleoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 -r_3579 stearoyl-CoA transport, cytoplasm-lipid particle stearoyl-CoA --> stearoyl-CoA -6.04871976524318e-13 +r_3578 palmitoleoyl-CoA transport, cytoplasm-lipid particle palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 1000.0 +r_3578_REV palmitoleoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 1000.0 +r_3579 stearoyl-CoA transport, cytoplasm-lipid particle stearoyl-CoA --> stearoyl-CoA 0.0006939317480827291 r_3579_REV stearoyl-CoA transport, cytoplasm-lipid particle (reversible) stearoyl-CoA --> stearoyl-CoA 0.0 -r_3580 oleoyl-CoA transport, cytoplasm-lipid particle oleoyl-CoA --> oleoyl-CoA 9.967207815371254e-05 +r_3580 oleoyl-CoA transport, cytoplasm-lipid particle oleoyl-CoA --> oleoyl-CoA 0.0006939317480827291 r_3580_REV oleoyl-CoA transport, cytoplasm-lipid particle (reversible) oleoyl-CoA --> oleoyl-CoA 0.0 -r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle glycerol 3-phosphate --> glycerol 3-phosphate -6.04871976524318e-13 +r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle glycerol 3-phosphate --> glycerol 3-phosphate 0.0006939317480827291 r_3581_REV glycerol 3-phosphate transport, cytoplasm-lipid particle (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3582 dihydroxyacetone phosphate transport, cytoplasm-lipid particle dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3582_REV dihydroxyacetone phosphate transport, cytoplasm-lipid particle (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 @@ -4777,10 +4777,10 @@ r_3583_REV NADPH transport, cytoplasm-lipid particle (reversible) NADPH --> NADP r_3584 NADP(+) transport, cytoplasm-lipid particle NADP(+) --> NADP(+) 0.0 r_3584_REV NADP(+) transport, cytoplasm-lipid particle (reversible) NADP(+) --> NADP(+) 0.0 r_3585 ATP transport, cytoplasm-lipid particle ATP --> ATP 0.0 -r_3585_REV ATP transport, cytoplasm-lipid particle (reversible) ATP --> ATP 0.0006103874711424513 -r_3586 AMP transport, cytoplasm-lipid particle AMP --> AMP 0.0006103874711424513 +r_3585_REV ATP transport, cytoplasm-lipid particle (reversible) ATP --> ATP 0.0 +r_3586 AMP transport, cytoplasm-lipid particle AMP --> AMP 0.0 r_3586_REV AMP transport, cytoplasm-lipid particle (reversible) AMP --> AMP 0.0 -r_3587 diphosphate transport, cytoplasm-lipid particle diphosphate --> diphosphate 0.0006103874711424513 +r_3587 diphosphate transport, cytoplasm-lipid particle diphosphate --> diphosphate 0.0 r_3587_REV diphosphate transport, cytoplasm-lipid particle (reversible) diphosphate --> diphosphate 0.0 r_3588 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3588_REV diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 @@ -4790,7 +4790,7 @@ r_3590 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle diglycer r_3590_REV diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3591 diglyceride (1-18:1, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3591_REV diglyceride (1-18:1, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 -r_3592 diglyceride (1-16:0, 2-18:1) transport, cytoplasm-lipid particle diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 9.236923130306665e-05 +r_3592 diglyceride (1-16:0, 2-18:1) transport, cytoplasm-lipid particle diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3592_REV diglyceride (1-16:0, 2-18:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3593 diglyceride (1-16:1, 2-18:1) transport, cytoplasm-lipid particle diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3593_REV diglyceride (1-16:1, 2-18:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 @@ -4812,10 +4812,10 @@ r_3601 ATP transport, cytoplasm-cell envelope ATP --> ATP 0.0 r_3601_REV ATP transport, cytoplasm-cell envelope (reversible) ATP --> ATP 0.0 r_3602 ADP transport, cytoplasm-cell envelope ADP --> ADP 0.0 r_3602_REV ADP transport, cytoplasm-cell envelope (reversible) ADP --> ADP 0.0 -r_3603 H+ transport, cytoplasm-cell envelope H+ --> H+ 0.003399616352539276 +r_3603 H+ transport, cytoplasm-cell envelope H+ --> H+ 0.0033996163525392663 r_3603_REV H+ transport, cytoplasm-cell envelope (reversible) H+ --> H+ 0.0 r_3604_EXP_1 H2O transport, cytoplasm-cell envelope 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 -r_3604_EXP_2 H2O transport, cytoplasm-cell envelope 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.003399616352539276 +r_3604_EXP_2 H2O transport, cytoplasm-cell envelope 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0033996163525392663 r_3604_EXP_3 H2O transport, cytoplasm-cell envelope 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_3604_REV_EXP_1 H2O transport, cytoplasm-cell envelope (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_3604_REV_EXP_2 H2O transport, cytoplasm-cell envelope (reversible) 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0 @@ -4938,35 +4938,35 @@ r_3660 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transpor r_3660_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) 0.0 r_3661 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 r_3661_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 -r_3662 H2O transport, cytoplasm-Golgi membrane H2O --> H2O -6.04871976524318e-13 +r_3662 H2O transport, cytoplasm-Golgi membrane H2O --> H2O 0.004251521736037288 r_3662_REV H2O transport, cytoplasm-Golgi membrane (reversible) H2O --> H2O 0.0 r_3663 phosphate transport, cytoplasm-Golgi membrane phosphate --> phosphate 0.0 -r_3663_REV phosphate transport, cytoplasm-Golgi membrane (reversible) phosphate --> phosphate -6.04871976524318e-13 +r_3663_REV phosphate transport, cytoplasm-Golgi membrane (reversible) phosphate --> phosphate 0.004251521736037288 r_3664 H+ transport, cytoplasm-Golgi membrane H+ --> H+ 0.0 -r_3664_REV H+ transport, cytoplasm-Golgi membrane (reversible) H+ --> H+ -1.209743953048636e-12 +r_3664_REV H+ transport, cytoplasm-Golgi membrane (reversible) H+ --> H+ 0.008503043472074576 r_3665 carbon dioxide transport, cytoplasm-Golgi membrane carbon dioxide --> carbon dioxide 0.0 r_3665_REV carbon dioxide transport, cytoplasm-Golgi membrane (reversible) carbon dioxide --> carbon dioxide 0.0 r_3666 ATP transport, cytoplasm-Golgi membrane ATP --> ATP 0.0 r_3666_REV ATP transport, cytoplasm-Golgi membrane (reversible) ATP --> ATP 0.0 r_3667 ADP transport, cytoplasm-Golgi membrane ADP --> ADP 0.0 r_3667_REV ADP transport, cytoplasm-Golgi membrane (reversible) ADP --> ADP 0.0 -r_3668 H2O transport, cytoplasm-mitochondrial membrane H2O --> H2O 0.12998345297885017 +r_3668 H2O transport, cytoplasm-mitochondrial membrane H2O --> H2O 0.0 r_3668_REV H2O transport, cytoplasm-mitochondrial membrane (reversible) H2O --> H2O 0.0 r_3669 carbon dioxide transport, cytoplasm-mitochondrial membrane carbon dioxide --> carbon dioxide 0.0 -r_3669_REV carbon dioxide transport, cytoplasm-mitochondrial membrane (reversible) carbon dioxide --> carbon dioxide 0.0044105572171690656 +r_3669_REV carbon dioxide transport, cytoplasm-mitochondrial membrane (reversible) carbon dioxide --> carbon dioxide 0.004410557217169058 r_3670 palmitoleoyl-CoA transport, cytoplasm-mitochondrial membrane palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3670_REV palmitoleoyl-CoA transport, cytoplasm-mitochondrial membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3671 oleoyl-CoA transport, cytoplasm-mitochondrial membrane oleoyl-CoA --> oleoyl-CoA 0.0 r_3671_REV oleoyl-CoA transport, cytoplasm-mitochondrial membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.0 r_3672 diglyceride (1-16:0, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3672_REV diglyceride (1-16:0, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3673 diglyceride (1-16:1, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0008519053834980207 +r_3673 diglyceride (1-16:1, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3673_REV diglyceride (1-16:1, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 -r_3674 diglyceride (1-18:0, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.06143413650147051 +r_3674 diglyceride (1-18:0, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3674_REV diglyceride (1-18:0, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3675 diglyceride (1-18:1, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3675_REV diglyceride (1-18:1, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 -r_3676 diglyceride (1-16:0, 2-18:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0027056846044565467 +r_3676 diglyceride (1-16:0, 2-18:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3676_REV diglyceride (1-16:0, 2-18:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3677 diglyceride (1-16:1, 2-18:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3677_REV diglyceride (1-16:1, 2-18:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 @@ -5023,7 +5023,7 @@ r_3702_REV TAG (1-16:0, 2-18:1, 3-16:1) transport, ER membrane-lipid particle (r r_3703 TAG (1-16:0, 2-18:1, 3-18:0) transport, ER membrane-lipid particle triglyceride (1-16:0, 2-18:1, 3-18:0) --> triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 r_3703_REV TAG (1-16:0, 2-18:1, 3-18:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:0, 2-18:1, 3-18:0) --> triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 r_3704 TAG (1-16:0, 2-18:1, 3-18:1) transport, ER membrane-lipid particle triglyceride (1-16:0, 2-18:1, 3-18:1) --> triglyceride (1-16:0, 2-18:1, 3-18:1) 0.0 -r_3704_REV TAG (1-16:0, 2-18:1, 3-18:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:0, 2-18:1, 3-18:1) --> triglyceride (1-16:0, 2-18:1, 3-18:1) 9.236923130306665e-05 +r_3704_REV TAG (1-16:0, 2-18:1, 3-18:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:0, 2-18:1, 3-18:1) --> triglyceride (1-16:0, 2-18:1, 3-18:1) 0.0 r_3705 TAG (1-16:1, 2-18:1, 3-16:0) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-18:1, 3-16:0) --> triglyceride (1-16:1, 2-18:1, 3-16:0) 0.0 r_3705_REV TAG (1-16:1, 2-18:1, 3-16:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-18:1, 3-16:0) --> triglyceride (1-16:1, 2-18:1, 3-16:0) 0.0 r_3706 TAG (1-16:1, 2-18:1, 3-16:1) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-18:1, 3-16:1) --> triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 @@ -5128,19 +5128,19 @@ r_3755 phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane phos r_3755_REV phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3756 phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3756_REV phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) -6.04871976524318e-13 +r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0006939317480827291 r_3757_REV phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 r_3758 phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3758_REV phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3759 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 r_3759_REV phosphatidate (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 -r_3760 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0008519053834980207 +r_3760 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3760_REV phosphatidate (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 -r_3761 phosphatidate (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.06143413650147051 +r_3761 phosphatidate (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3761_REV phosphatidate (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3762 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3762_REV phosphatidate (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 -r_3763 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0027056846044565467 +r_3763 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3763_REV phosphatidate (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3764 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3764_REV phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 @@ -5150,9 +5150,9 @@ r_3766 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-mitochondri r_3766_REV phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:1, 2-16:1) --> phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0 r_3767 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 r_3767_REV phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_3768 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.003399616352539276 +r_3768 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0033996163525392663 r_3768_REV phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0 -r_3769 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 3.685114303957405e-06 +r_3769 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 3.6851143039589006e-06 r_3769_REV phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 r_3770 phosphatidyl-L-serine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:1, 2-18:1) --> phosphatidyl-L-serine (1-16:1, 2-18:1) 0.0 r_3770_REV phosphatidyl-L-serine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:1, 2-18:1) --> phosphatidyl-L-serine (1-16:1, 2-18:1) 0.0 @@ -5166,9 +5166,9 @@ r_3774 phosphatidylethanolamine (1-16:1, 2-16:1) transport, mitochondrial membra r_3774_REV phosphatidylethanolamine (1-16:1, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:1, 2-16:1) --> phosphatidylethanolamine (1-16:1, 2-16:1) 0.0 r_3775 phosphatidylethanolamine (1-18:0, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 r_3775_REV phosphatidylethanolamine (1-18:0, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_3776 phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.003399616352539276 +r_3776 phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0033996163525392663 r_3776_REV phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0 -r_3777 phosphatidylethanolamine (1-16:0, 2-18:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 3.685114303957405e-06 +r_3777 phosphatidylethanolamine (1-16:0, 2-18:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 3.6851143039589006e-06 r_3777_REV phosphatidylethanolamine (1-16:0, 2-18:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_3778 phosphatidylethanolamine (1-16:1, 2-18:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-16:1, 2-18:1) --> phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_3778_REV phosphatidylethanolamine (1-16:1, 2-18:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:1, 2-18:1) --> phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 @@ -5193,34 +5193,34 @@ r_3787_REV phosphatidylcholine (1-18:0, 2-18:1) transport, ER membrane-mitochond r_3788 phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:1, 2-18:1) --> phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_3788_REV phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:1, 2-18:1) --> phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_3789 diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3789_REV diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 +r_3789_REV diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.000601562517384425 r_3790 diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 -r_3790_REV diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 +r_3790_REV diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0008519053834980219 r_3791 diglyceride (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3791_REV diglyceride (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3792 diglyceride (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3792_REV diglyceride (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3793 diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 -r_3793_REV diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 +r_3793_REV diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.002104122087072112 r_3794 diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3794_REV diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3795 diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 -r_3795_REV diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) -6.04871976524318e-13 +r_3795_REV diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0006939317480827291 r_3796 diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 r_3796_REV diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 -r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 +r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.000601562517384425 r_3797_REV phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 -r_3798 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 +r_3798 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0008519053834980219 r_3798_REV phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3799 phosphatidate (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3799_REV phosphatidate (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3800 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3800_REV phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 -r_3801 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 +r_3801 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.002104122087072112 r_3801_REV phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3802 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3802_REV phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) -6.04871976524318e-13 +r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0006939317480827291 r_3803_REV phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 r_3804 phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3804_REV phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 @@ -5390,7 +5390,7 @@ r_3878 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope r_3878_REV phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_3879 phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_3879_REV phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 -r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.003399616352539276 +r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0033996163525392663 r_3880_REV phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_3881 phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_3881_REV phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 @@ -5442,7 +5442,7 @@ r_3904 phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane phosp r_3904_REV phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3905 phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3905_REV phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 -r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.003399616352539276 +r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0033996163525392663 r_3906_REV phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3907 phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3907_REV phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 @@ -5508,7 +5508,7 @@ r_3937 lignoceric acid transport, ER membrane-ER lignoceric acid --> lignoceric r_3937_REV lignoceric acid transport, ER membrane-ER (reversible) lignoceric acid --> lignoceric acid 0.0 r_3938 cerotic acid transport, ER membrane-ER cerotic acid --> cerotic acid 0.0 r_3938_REV cerotic acid transport, ER membrane-ER (reversible) cerotic acid --> cerotic acid 0.0 -r_3939 ergosterol transport, ER-ER membrane ergosterol --> ergosterol 0.003720927744308719 +r_3939 ergosterol transport, ER-ER membrane ergosterol --> ergosterol 0.003720927744308722 r_3939_REV ergosterol transport, ER-ER membrane (reversible) ergosterol --> ergosterol 0.0 r_3940 phosphate transport, ER-ER membrane phosphate --> phosphate 0.0 r_3941 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) transport, vacuolar membrane-Golgi membrane 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) 0.0 @@ -5544,19 +5544,19 @@ r_3955_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) tran r_3956 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cell envelope 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 r_3956_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cell envelope (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 r_3957 H+ transport, mitochondrion-mitochondrial membrane H+ --> H+ 0.0 -r_3957_REV H+ transport, mitochondrion-mitochondrial membrane (reversible) H+ --> H+ 0.19497517946827522 +r_3957_REV H+ transport, mitochondrion-mitochondrial membrane (reversible) H+ --> H+ 0.0 r_3958 glycerol 3-phosphate transport, mitochondrion-mitochondrial membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3958_REV glycerol 3-phosphate transport, mitochondrion-mitochondrial membrane (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3959 CMP transport, mitochondrion-mitochondrial membrane 0.2701553629071786 prot_P38127 + CMP --> CMP 0.0 -r_3959_REV CMP transport, mitochondrion-mitochondrial membrane (reversible) 0.2701553629071786 prot_P38127 + CMP --> CMP 0.06499172648942508 -r_3960 CTP transport, mitochondrion-mitochondrial membrane 0.5351086635753655 prot_P38127 + CTP --> CTP 0.06499172648942508 +r_3959_REV CMP transport, mitochondrion-mitochondrial membrane (reversible) 0.2701553629071786 prot_P38127 + CMP --> CMP 0.0 +r_3960 CTP transport, mitochondrion-mitochondrial membrane 0.5351086635753655 prot_P38127 + CTP --> CTP 0.0 r_3960_REV CTP transport, mitochondrion-mitochondrial membrane (reversible) 0.5351086635753655 prot_P38127 + CTP --> CTP 0.0 r_3961_EXP_1 phosphate transport, mitochondrion-mitochondrial membrane 0.8466666666666667 prot_P40035 + phosphate --> phosphate 0.0 r_3961_EXP_2 phosphate transport, mitochondrion-mitochondrial membrane 0.8285858585858585 prot_P23641 + phosphate --> phosphate 0.0 -r_3961_REV_EXP_1 phosphate transport, mitochondrion-mitochondrial membrane (reversible) 0.8466666666666667 prot_P40035 + phosphate --> phosphate 0.02044328373360127 -r_3961_REV_EXP_2 phosphate transport, mitochondrion-mitochondrial membrane (reversible) 0.8285858585858585 prot_P23641 + phosphate --> phosphate 0.04454844275582384 +r_3961_REV_EXP_1 phosphate transport, mitochondrion-mitochondrial membrane (reversible) 0.8466666666666667 prot_P40035 + phosphate --> phosphate 0.0 +r_3961_REV_EXP_2 phosphate transport, mitochondrion-mitochondrial membrane (reversible) 0.8285858585858585 prot_P23641 + phosphate --> phosphate 0.0 r_3962 diphosphate transport, mitochondrion-mitochondrial membrane diphosphate --> diphosphate 0.0 -r_3962_REV diphosphate transport, mitochondrion-mitochondrial membrane (reversible) diphosphate --> diphosphate 0.06499172648942507 +r_3962_REV diphosphate transport, mitochondrion-mitochondrial membrane (reversible) diphosphate --> diphosphate 0.0 r_3963 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) --> 0.809028342 1-phosphatidyl-1D-myo-inositol backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0 r_3964 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) --> 0.807012462 1-phosphatidyl-1D-myo-inositol backbone + 0.508826 C16:1 chain 0.0008562816933829467 r_3965 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 @@ -5565,16 +5565,16 @@ r_3967 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) [cytoplasm] SLIME rxn 1-p r_3968 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_3969 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> 0.865135862 1-phosphatidyl-1D-myo-inositol backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_3970 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> 0.863119982 1-phosphatidyl-1D-myo-inositol backbone + 0.56493352 C18:1 chain 0.0 -r_3971 ergosteryl palmitoleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl palmitoleate --> 0.63305448 ergosterol ester backbone + 0.254413 C16:1 chain 0.0007820180262607629 -r_3972 ergosteryl oleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl oleate --> 0.66110824 ergosterol ester backbone + 0.28246676 C18:1 chain 0.0002806196932011564 +r_3971 ergosteryl palmitoleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl palmitoleate --> 0.63305448 ergosterol ester backbone + 0.254413 C16:1 chain 0.0007820180262608282 +r_3972 ergosteryl oleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl oleate --> 0.66110824 ergosterol ester backbone + 0.28246676 C18:1 chain 0.0002806196932010939 r_3973 ergosterol ester transport, ER membrane-cytoplasm ergosterol ester backbone --> ergosterol ester backbone 0.00068058000644669 r_3973_REV ergosterol ester transport, ER membrane-cytoplasm (reversible) ergosterol ester backbone --> ergosterol ester backbone 0.0 r_3975 palmitate [cytoplasm] SLIME rxn H+ + palmitate --> 0.25542094 fatty acid backbone + 0.25642888 C16:0 chain 0.0 r_3976 palmitoleate [cytoplasm] SLIME rxn H+ + palmitoleate --> 0.25340506 fatty acid backbone + 0.254413 C16:1 chain 0.0005840846230801192 r_3977 stearate [cytoplasm] SLIME rxn H+ + stearate --> 0.2834747 fatty acid backbone + 0.28448264 C18:0 chain 0.0 r_3978 oleate [cytoplasm] SLIME rxn H+ + oleate --> 0.28145882 fatty acid backbone + 0.28246676 C18:1 chain 0.0 -r_3979 phosphatidyl-L-serine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:0, 2-16:1) --> 0.733964182 phosphatidyl-L-serine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0004438790033342618 -r_3980 phosphatidyl-L-serine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:1, 2-16:1) --> 0.731948302 phosphatidyl-L-serine backbone + 0.508826 C16:1 chain 0.0003679067615155614 +r_3979 phosphatidyl-L-serine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:0, 2-16:1) --> 0.733964182 phosphatidyl-L-serine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.00044387900333427036 +r_3980 phosphatidyl-L-serine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:1, 2-16:1) --> 0.731948302 phosphatidyl-L-serine backbone + 0.508826 C16:1 chain 0.0003679067615155532 r_3981 phosphatidyl-L-serine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:0, 2-16:1) --> 0.762017942 phosphatidyl-L-serine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_3982 phosphatidyl-L-serine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:1, 2-16:1) --> 0.760002062 phosphatidyl-L-serine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_3983 phosphatidyl-L-serine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:0, 2-18:1) --> 0.762017942 phosphatidyl-L-serine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5583,13 +5583,13 @@ r_3985 phosphatidyl-L-serine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] S r_3986 phosphatidyl-L-serine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:1, 2-18:1) --> 0.788055822 phosphatidyl-L-serine backbone + 0.56493352 C18:1 chain 0.0 r_3987 phosphatidyl-L-serine transport, ER membrane-cytoplasm phosphatidyl-L-serine backbone --> phosphatidyl-L-serine backbone 0.000595080018974841 r_3987_REV phosphatidyl-L-serine transport, ER membrane-cytoplasm (reversible) phosphatidyl-L-serine backbone --> phosphatidyl-L-serine backbone 0.0 -r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-16:1) --> 0.732035022 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0 +r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-16:1) --> 0.732035022 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.000601562517384425 r_3989 phosphatidylcholine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-16:1) --> 0.730019142 phosphatidylcholine backbone + 0.508826 C16:1 chain 0.0 -r_3990 phosphatidylcholine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-16:1) --> 0.744089382 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0006015625173845342 +r_3990 phosphatidylcholine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-16:1) --> 0.744089382 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_3991 phosphatidylcholine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-16:1) --> 0.742073502 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-18:1) --> 0.760088782 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0027093697187605043 +r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-18:1) --> 0.760088782 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.002107807201376071 r_3993 phosphatidylcholine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-18:1) --> 0.758072902 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-18:1) --> 0.772143142 phosphatidylcholine backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 9.236923069819467e-05 +r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-18:1) --> 0.772143142 phosphatidylcholine backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0006939317480827291 r_3995 phosphatidylcholine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-18:1) --> 0.770127262 phosphatidylcholine backbone + 0.56493352 C18:1 chain 0.0 r_3996 phosphatidylcholine transport, ER membrane-cytoplasm phosphatidylcholine backbone --> phosphatidylcholine backbone 0.0025783000793308 r_3996_REV phosphatidylcholine transport, ER membrane-cytoplasm (reversible) phosphatidylcholine backbone --> phosphatidylcholine backbone 0.0 @@ -5613,7 +5613,7 @@ r_4012 triglyceride (1-18:1, 2-16:1, 3-16:0) [endoplasmic reticulum membrane] SL r_4013 triglyceride (1-18:1, 2-18:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-16:0) --> 0.85941128 triglyceride backbone + 0.25642888 C16:0 chain + 0.56493352 C18:1 chain 0.0 r_4014 triglyceride (1-16:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-16:1) --> 0.80330376 triglyceride backbone + 0.25642888 C16:0 chain + 0.508826 C16:1 chain 0.0 r_4015 triglyceride (1-16:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-18:1, 3-16:1) --> 0.83135752 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-16:1) --> 0.80128788 triglyceride backbone + 0.763239 C16:1 chain 0.0007491923956637266 +r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-16:1) --> 0.80128788 triglyceride backbone + 0.763239 C16:1 chain 0.0007491923956637269 r_4017 triglyceride (1-16:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-18:1, 3-16:1) --> 0.82934164 triglyceride backbone + 0.508826 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_4018 triglyceride (1-18:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-16:1, 3-16:1) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_4019 triglyceride (1-18:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-18:1, 3-16:1) --> 0.85941128 triglyceride backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5621,7 +5621,7 @@ r_4020 triglyceride (1-18:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SL r_4021 triglyceride (1-18:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-16:1) --> 0.8573954 triglyceride backbone + 0.254413 C16:1 chain + 0.56493352 C18:1 chain 0.0 r_4022 triglyceride (1-16:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-18:0) --> 0.8333734 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_4023 triglyceride (1-16:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-18:1, 3-18:0) --> 0.86142716 triglyceride backbone + 0.25642888 C16:0 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 -r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-18:0) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.00010271298783429586 +r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-18:0) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.00010271298783429566 r_4025 triglyceride (1-16:1, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-18:1, 3-18:0) --> 0.85941128 triglyceride backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_4026 triglyceride (1-18:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-16:1, 3-18:0) --> 0.86142716 triglyceride backbone + 0.254413 C16:1 chain + 0.56896528 C18:0 chain 0.0 r_4027 triglyceride (1-18:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-18:1, 3-18:0) --> 0.88948092 triglyceride backbone + 0.56896528 C18:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5904,7 +5904,7 @@ r_4195_EXP_1 Zinc transporter YKE4 1.2208333333333334 prot_P20107 + Zn(2+) --> Z r_4195_EXP_2 Zinc transporter YKE4 1.2160353535353536 prot_P32798 + Zn(2+) --> Zn(2+) 0.0 r_4195_REV_EXP_1 Zinc transporter YKE4 (reversible) 1.2208333333333334 prot_P20107 + Zn(2+) --> Zn(2+) 0.0 r_4195_REV_EXP_2 Zinc transporter YKE4 (reversible) 1.2160353535353536 prot_P32798 + Zn(2+) --> Zn(2+) 0.0 -r_4196_EXP_1 NADH:ferricytochrome-b5 oxidoreductase 0.007953030303030304 prot_P38626 + NADH + 2.0 ferricytochrome b5 --> H+ + NAD + 2.0 ferrocytochrome b5 0.011173862031936094 +r_4196_EXP_1 NADH:ferricytochrome-b5 oxidoreductase 0.007953030303030304 prot_P38626 + NADH + 2.0 ferricytochrome b5 --> H+ + NAD + 2.0 ferrocytochrome b5 0.011173862031931034 r_4196_EXP_2 NADH:ferricytochrome-b5 oxidoreductase 0.008910858585858586 prot_Q12746 + NADH + 2.0 ferricytochrome b5 --> H+ + NAD + 2.0 ferrocytochrome b5 0.0 r_4196_REV_EXP_1 NADH:ferricytochrome-b5 oxidoreductase (reversible) 0.02916111111111111 prot_P38626 + H+ + NAD + 2.0 ferrocytochrome b5 --> NADH + 2.0 ferricytochrome b5 0.0 r_4196_REV_EXP_2 NADH:ferricytochrome-b5 oxidoreductase (reversible) 0.032673148148148146 prot_Q12746 + H+ + NAD + 2.0 ferrocytochrome b5 --> NADH + 2.0 ferricytochrome b5 0.0 @@ -5944,7 +5944,7 @@ r_4212_REV_EXP_2 D-ribulose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5 r_4214 L-cysteinylglycine dipeptidase 0.44291358035466905 prot_P43616 + H2O + L-cysteinylglycine --> L-cysteine + L-glycine 0.0 r_4214_REV L-cysteinylglycine dipeptidase (reversible) 1.1513279129330525 prot_P43616 + L-cysteine + L-glycine --> H2O + L-cysteinylglycine 0.0 r_4216 riboflavin-5-phosphate phosphohydrolase 2.307741115456161 prot_P52290 + FMN + H2O --> phosphate + riboflavin 0.0 -r_4216_REV riboflavin-5-phosphate phosphohydrolase (reversible) 1.7221699633075207 prot_P52290 + phosphate + riboflavin --> FMN + H2O 9.99999974737875e-07 +r_4216_REV riboflavin-5-phosphate phosphohydrolase (reversible) 1.7221699633075207 prot_P52290 + phosphate + riboflavin --> FMN + H2O 0.0 r_4217 Fe(II):oxygen oxidoreductase; Fe2+:oxygen oxidoreductase 2.4608585858585856 prot_Q07540 + 4.0 H+ + 4.0 iron(2+) + oxygen --> 2.0 H2O + 4.0 iron(3+) 0.0 r_4217_REV Fe(II):oxygen oxidoreductase; Fe2+:oxygen oxidoreductase (reversible) 2.4608585858585856 prot_Q07540 + 2.0 H2O + 4.0 iron(3+) --> 4.0 H+ + 4.0 iron(2+) + oxygen 0.0 r_4218 D-aminoacyl-tRNA deacylase (DTD) (EC 3.1.1.96) (D-tyrosyl-tRNA(Tyr) deacylase) (Gly-tRNA(Ala) deacylase) (EC 3.1.1.-) 0.015505555555555555 prot_Q07648 + H2O + Glycyl-tRNA(Ala) --> H+ + L-glycine + tRNA(Ala) 0.0 @@ -6127,7 +6127,7 @@ r_4328_REV UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase (reversible) r_4329 Putative sulfate transporter YPR003C 2.105656565656566 prot_P53394 + sulphate --> sulphate 0.0 r_4329_REV Putative sulfate transporter YPR003C (reversible) 2.105656565656566 prot_P53394 + sulphate --> sulphate 0.0 r_4330 Pyridoxine:NADP+ 4-oxidoreductase 28.426997929479914 prot_Q06494 + NADP(+) + pyridoxine --> H+ + NADPH + pyridoxal 0.0 -r_4330_REV Pyridoxine:NADP+ 4-oxidoreductase (reversible) 7.099034416207216 prot_Q06494 + H+ + NADPH + pyridoxal --> NADP(+) + pyridoxine 0.00687413438446844 +r_4330_REV Pyridoxine:NADP+ 4-oxidoreductase (reversible) 7.099034416207216 prot_Q06494 + H+ + NADPH + pyridoxal --> NADP(+) + pyridoxine 0.0 r_4331_EXP_1 [1,4-(N-Acetyl-beta-D-glucosaminyl)]n glycanohydrolase 0.19676092339643741 prot_Q06350 + chitin + H2O --> N-Acetyl-D-glucosamine 0.0 r_4331_EXP_2 [1,4-(N-Acetyl-beta-D-glucosaminyl)]n glycanohydrolase 0.1964181111377373 prot_P29029 + chitin + H2O --> N-Acetyl-D-glucosamine 0.0 r_4331_REV_EXP_1 [1,4-(N-Acetyl-beta-D-glucosaminyl)]n glycanohydrolase (reversible) 12.632051282051282 prot_Q06350 + N-Acetyl-D-glucosamine --> chitin + H2O 0.0 @@ -6136,7 +6136,7 @@ r_4332 Protein PNS1 (pH nine-sensitive protein 1) 4.890140948879145 prot_Q12412 r_4332_REV Protein PNS1 (pH nine-sensitive protein 1) (reversible) 4.890140948879145 prot_Q12412 + choline --> choline 0.0 r_4333_EXP_1 Polyphosphate phosphohydrolase 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4333_EXP_2 Polyphosphate phosphohydrolase 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 -r_4333_REV_EXP_1 Polyphosphate phosphohydrolase (reversible) 0.008073655913978494 prot_P38698 + H+ + 2.0 phosphate --> H2O + polyphosphate 2.1847137327624497 +r_4333_REV_EXP_1 Polyphosphate phosphohydrolase (reversible) 0.008073655913978494 prot_P38698 + H+ + 2.0 phosphate --> H2O + polyphosphate 0.9824006928676805 r_4333_REV_EXP_2 Polyphosphate phosphohydrolase (reversible) 0.014040143369175627 prot_Q04119 + H+ + 2.0 phosphate --> H2O + polyphosphate 2.0054985466536426 r_4334 Copper-transporting ATPase (EC 3.6.3.54) (Cu(2+)-ATPase) 117.33867521367522 prot_P38995 + ATP + H2O + Cu2(+) --> ADP + H+ + phosphate + Cu2(+) 0.0 r_4335 Endopolyphosphatase (EC 3.6.1.10) (Deoxyadenosine triphosphate phosphohydrolase) (dATP phosphohydrolase) (EC 3.6.1.-) (Exopolyphosphatase) (EC 3.6.1.11) (Phosphate metabolism protein 5) 0.014040143369175627 prot_Q04119 + dATP + H2O --> dADP + H+ + phosphate 0.0 @@ -6394,17 +6394,17 @@ r_4484_EXP_3 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropy r_4484_REV_EXP_1 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) (reversible) 0.16609504132231406 prot_P47164 + L-homocysteine + succinate --> hydrogen sulfide + O-succinyl-L-homoserine 0.0 r_4484_REV_EXP_2 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) (reversible) 11.75934135228728 prot_Q12198 + L-homocysteine + succinate --> hydrogen sulfide + O-succinyl-L-homoserine 0.0 r_4484_REV_EXP_3 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) (reversible) 0.170599173553719 prot_Q04533 + L-homocysteine + succinate --> hydrogen sulfide + O-succinyl-L-homoserine 0.0 -r_4485 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) 1.1329040404040405 prot_standard + 3-(4-hydroxyphenyl)pyruvate + oxygen --> carbon dioxide + homogentisate 0.012490712595843527 -r_4486 Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) 1.1329040404040405 prot_standard + oxygen + homogentisate --> H+ + 4-maleylacetoacetate 0.012490712595843527 -r_4487 4-Maleylacetoacetate cis-trans-isomerase 1.1329040404040405 prot_standard + 4-maleylacetoacetate --> 4-fumarylacetoacetate 0.012490712595843527 -r_4488 4-fumarylacetoacetate fumarylhydrolase 1.1329040404040405 prot_standard + H2O + 4-fumarylacetoacetate --> fumarate + H+ + acetoacetate 0.012490712595843527 +r_4485 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) 1.1329040404040405 prot_standard + 3-(4-hydroxyphenyl)pyruvate + oxygen --> carbon dioxide + homogentisate 0.0 +r_4486 Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) 1.1329040404040405 prot_standard + oxygen + homogentisate --> H+ + 4-maleylacetoacetate 0.0 +r_4487 4-Maleylacetoacetate cis-trans-isomerase 1.1329040404040405 prot_standard + 4-maleylacetoacetate --> 4-fumarylacetoacetate 0.0 +r_4488 4-fumarylacetoacetate fumarylhydrolase 1.1329040404040405 prot_standard + H2O + 4-fumarylacetoacetate --> fumarate + H+ + acetoacetate 0.0 r_4489 L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming) 1.1329040404040405 prot_standard + L-arabinitol + NAD --> H+ + NADH + L-xylulose 0.0 r_4490 Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) 1.1329040404040405 prot_standard + H+ + NADPH + L-xylulose --> NADP(+) + xylitol 0.0 r_4490_REV Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) (reversible) 1.1329040404040405 prot_standard + NADP(+) + xylitol --> H+ + NADPH + L-xylulose 0.0 r_4491 arabinose reductase (D-arabinose) 0.45405614353626883 prot_standard + D-arabinose + H+ + NADPH --> NADP(+) + D-arabinitol 0.0 r_4492 D-arabinitol:NAT 4-oxidoreductase 1.1329040404040405 prot_standard + NAD + D-arabinitol --> D-xylulose + H+ + NADH 0.0 r_4493 Acetoacetate transport via diffusion 83.31663433619322 prot_P53943 + acetoacetate --> acetoacetate 0.0 -r_4493_REV Acetoacetate transport via diffusion (reversible) 83.31663433619322 prot_P53943 + acetoacetate --> acetoacetate 0.012490712595843527 +r_4493_REV Acetoacetate transport via diffusion (reversible) 83.31663433619322 prot_P53943 + acetoacetate --> acetoacetate 0.0 r_4494 methanol exchange methanol --> 0.0 r_4495 alkaline phosphatase 0.5934259259259259 prot_standard + adenosine 2'-phosphate + H2O --> adenosine + phosphate 0.0 r_4496 Ala-Gly exchange Ala-Gly --> 0.0 @@ -6466,7 +6466,7 @@ r_4551 3-sulfino-L-alanine exchange 3-sulfino-L-alanine --> 0.0 r_4552 N-acetyl-L-cysteine exchange N-acetyl-L-cysteine --> 0.0 r_4553 L-cysteate exchange L-cysteate --> 0.0 r_4554 2-hydroxyethane-1-sulfonate exchange 2-hydroxyethane-1-sulfonate --> 0.0 -r_4555 acetoacetate exchange acetoacetate --> 0.012490712595843527 +r_4555 acetoacetate exchange acetoacetate --> 0.0 r_4556 N-acetyl-L-glutamate exchange N-acetyl-L-glutamate --> 0.0 r_4557 UMP exchange UMP --> 0.0 r_4558 CMP exchange CMP --> 0.0 @@ -6481,17 +6481,17 @@ r_4567 6-phosphogluconate phosphatase 0.17308256172839506 prot_standard + 6-phos r_4569 Carboxylic ester hydrolases 0.45405614353626883 prot_standard + acetate + H+ + Hydroquinone --> H2O + 4-hydroxyphenyl acetate 0.0 r_4570_EXP_1 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + NAD + 2-hydroxyglutarate --> 2-oxoglutarate + H+ + NADH 0.0 r_4570_EXP_2 phosphoglycerate dehydrogenase 0.0036935786435786434 prot_P40054 + NAD + 2-hydroxyglutarate --> 2-oxoglutarate + H+ + NADH 0.0 -r_4570_REV_EXP_1 phosphoglycerate dehydrogenase (reversible) 0.005777687480247415 prot_P40510 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.0331050772104632 +r_4570_REV_EXP_1 phosphoglycerate dehydrogenase (reversible) 0.005777687480247415 prot_P40510 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.02279398205170935 r_4570_REV_EXP_2 phosphoglycerate dehydrogenase (reversible) 0.0057782518398121815 prot_P40054 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.0 -r_4571 seed:rxn00681 1.1329040404040405 prot_standard + coenzyme A + H+ + 2-hydroxyglutarate --> glyoxylate + H2O + propionyl-CoA 0.0331050772104632 +r_4571 seed:rxn00681 1.1329040404040405 prot_standard + coenzyme A + H+ + 2-hydroxyglutarate --> glyoxylate + H2O + propionyl-CoA 0.02279398205170935 r_4571_REV seed:rxn00681 (reversible) 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + 2-hydroxyglutarate 0.0 -r_4572 beta-alanine:2-oxoglutarate aminotransferase 1.1329040404040405 prot_standard + 2-oxoglutarate + beta-alanine --> L-glutamate + 3-oxopropanoate 0.002419747496091418 +r_4572 beta-alanine:2-oxoglutarate aminotransferase 1.1329040404040405 prot_standard + 2-oxoglutarate + beta-alanine --> L-glutamate + 3-oxopropanoate 0.0024197474960912665 r_4572_REV beta-alanine:2-oxoglutarate aminotransferase (reversible) 1.1329040404040405 prot_standard + L-glutamate + 3-oxopropanoate --> 2-oxoglutarate + beta-alanine 0.0 r_4573 3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NAD + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADH 0.0 -r_4574 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NADP(+) + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADPH 0.002419747496091418 +r_4574 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NADP(+) + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADPH 0.0024197474960912665 r_4575 3-oxopropanoate carboxy-lyase 0.45405614353626883 prot_standard + H+ + 3-oxopropanoate --> acetaldehyde + carbon dioxide 0.0 -r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.048490056204063985 prot_standard + NAD + (2R,3S)-3-methylmalate --> 2-oxobutanoate + carbon dioxide + NADH 0.03308607720985639 -r_4582 malate/beta-methylmalate synthase 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + (2R,3S)-3-methylmalate 0.03308607720985639 +r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.048490056204063985 prot_standard + NAD + (2R,3S)-3-methylmalate --> 2-oxobutanoate + carbon dioxide + NADH 0.022773982051123243 +r_4582 malate/beta-methylmalate synthase 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + (2R,3S)-3-methylmalate 0.022773982051123243 r_4583 palmitoyl-CoA hydrolase 2.0068374645606704 prot_standard + H2O + trans-2,cis-9-octadecadienoyl-CoA --> coenzyme A + H+ + (9Z,12Z)-octadecadienoate 0.0 r_4584_EXP_1 long-chain-fatty-acid---CoA ligase 745.8429118773946 prot_P30624 + ATP + coenzyme A + (9Z,12Z)-octadecadienoate --> AMP + diphosphate + trans-2,cis-9-octadecadienoyl-CoA 0.0 r_4584_EXP_2 long-chain-fatty-acid---CoA ligase 799.2145593869732 prot_P39518 + ATP + coenzyme A + (9Z,12Z)-octadecadienoate --> AMP + diphosphate + trans-2,cis-9-octadecadienoyl-CoA 0.0 @@ -6530,7 +6530,7 @@ r_4606 O-phosphoethanolamine transport H+ + O-phosphoethanolamine --> H+ + O-pho r_4606_REV O-phosphoethanolamine transport (reversible) H+ + O-phosphoethanolamine --> H+ + O-phosphoethanolamine 0.0 r_4607 phosphate transport phosphate --> phosphate 0.0 r_4607_REV phosphate transport (reversible) phosphate --> phosphate 0.0 -r_4608 propionyl-CoA transport ATP + H2O + propionyl-CoA --> ADP + H+ + phosphate + propionyl-CoA 1.9000000606814286e-05 +r_4608 propionyl-CoA transport ATP + H2O + propionyl-CoA --> ADP + H+ + phosphate + propionyl-CoA 2.0000000586106736e-05 r_4609 UDP transport UDP --> UDP 0.0 r_4609_REV UDP transport (reversible) UDP --> UDP 0.0 r_4610 UDP transport UDP --> UDP 0.0 @@ -6621,7 +6621,7 @@ r_4651_EXP_2 pyruvate decarboxylase (aldedyde-forming) 0.11780651340996169 prot_ r_4651_EXP_3 pyruvate decarboxylase (aldedyde-forming) 0.27738351254480287 prot_P16467 + 2-oxobutanoate + H+ --> carbon dioxide + propanal 0.0 r_4652_EXP_1 aldehyde dehydrogenase (1-propanol, NAD) 14.32572298325723 prot_P38113 + H+ + NADH + propanal --> NAD + propanol 0.0 r_4652_EXP_2 aldehyde dehydrogenase (1-propanol, NAD) 15.617199391171994 prot_P32771 + H+ + NADH + propanal --> NAD + propanol 0.0 -r_4652_EXP_3 aldehyde dehydrogenase (1-propanol, NAD) 0.011373148148148148 prot_P00330 + H+ + NADH + propanal --> NAD + propanol 1.9000000606814286e-05 +r_4652_EXP_3 aldehyde dehydrogenase (1-propanol, NAD) 0.011373148148148148 prot_P00330 + H+ + NADH + propanal --> NAD + propanol 0.0 r_4653_EXP_1 aldehyde dehydrogenase (1-propanol, NAD) 0.012698148148148148 prot_P10127 + H+ + NADH + propanal --> NAD + propanol 0.0 r_4653_EXP_2 aldehyde dehydrogenase (1-propanol, NAD) 15.361491628614916 prot_P07246 + H+ + NADH + propanal --> NAD + propanol 0.0 r_4654_EXP_1 aldehyde dehydrogenase (1-propanol, NADP) 1.6815384615384616 prot_P25377 + H+ + NADPH + propanal --> NADP(+) + propanol 0.0 @@ -6631,10 +6631,10 @@ r_4655 1-propyl alcohol transport, mitochondrial propanol --> propanol 0.0 r_4655_REV 1-propyl alcohol transport, mitochondrial (reversible) propanol --> propanol 0.0 r_4656 propanal transport, cytosol propanal --> propanal 0.0 r_4656_REV propanal transport, cytosol (reversible) propanal --> propanal 0.0 -r_4657 1-propyl alcohol transport, cytosol propanol --> propanol 1.9000000606814286e-05 +r_4657 1-propyl alcohol transport, cytosol propanol --> propanol 0.0 r_4657_REV 1-propyl alcohol transport, cytosol (reversible) propanol --> propanol 0.0 r_4658 propanal exchange propanal --> 0.0 -r_4659 propanol exchange propanol --> 1.9000000606814286e-05 +r_4659 propanol exchange propanol --> 0.0 r_4660 2-oxo acid decarboxylase 0.010556998556998556 prot_P38840 + 4-methylthio-2-oxobutanoate + H+ --> carbon dioxide + methional 0.0 r_4660_REV 2-oxo acid decarboxylase (reversible) 0.010556998556998556 prot_P38840 + carbon dioxide + methional --> 4-methylthio-2-oxobutanoate + H+ 0.0 r_4661_EXP_1 aldehyde dehydrogenase (methionol, NAD) 0.006354607630660375 prot_P38113 + H+ + NADH + methional --> NAD + methionol 0.0 @@ -6676,7 +6676,7 @@ r_4678_EXP_1 aldehyde dehydrogenase 0.483596214511041 prot_P47771 + H2O + NAD + r_4678_EXP_2 aldehyde dehydrogenase 0.7809503666102651 prot_P54114 + H2O + NAD + propanal --> H+ + NADH + propionate 0.0 r_4678_EXP_3 aldehyde dehydrogenase 5.830373503190885 prot_P46367 + H2O + NAD + propanal --> H+ + NADH + propionate 0.0 r_4678_REV_EXP_1 aldehyde dehydrogenase (reversible) 0.483596214511041 prot_P47771 + H+ + NADH + propionate --> H2O + NAD + propanal 0.0 -r_4678_REV_EXP_2 aldehyde dehydrogenase (reversible) 0.06410300925925926 prot_P54114 + H+ + NADH + propionate --> H2O + NAD + propanal 1.9000000606814286e-05 +r_4678_REV_EXP_2 aldehyde dehydrogenase (reversible) 0.06410300925925926 prot_P54114 + H+ + NADH + propionate --> H2O + NAD + propanal 0.0 r_4678_REV_EXP_3 aldehyde dehydrogenase (reversible) 4.681477254164319 prot_P46367 + H+ + NADH + propionate --> H2O + NAD + propanal 0.0 r_4679_EXP_1 short-chain-fatty-acid-CoA ligase (propionate) 745.8429118773946 prot_P30624 + ATP + coenzyme A + propionate --> AMP + diphosphate + H+ + propionyl-CoA 0.0 r_4679_EXP_2 short-chain-fatty-acid-CoA ligase (propionate) 799.2145593869732 prot_P39518 + ATP + coenzyme A + propionate --> AMP + diphosphate + H+ + propionyl-CoA 0.0 @@ -6685,13 +6685,13 @@ r_4679_EXP_4 short-chain-fatty-acid-CoA ligase (propionate) 740.1053639846743 pr r_4679_REV_EXP_1 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 4.2393447911960855 prot_P30624 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 r_4679_REV_EXP_2 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 85.88964551313514 prot_P39518 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 r_4679_REV_EXP_3 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 57.978811271186636 prot_P39002 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 -r_4679_REV_EXP_4 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 2.7763568922936326 prot_P47912 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 1.9000000606814286e-05 +r_4679_REV_EXP_4 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 2.7763568922936326 prot_P47912 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 r_4680_EXP_1 alcohol acyltransferase (propionyl-CoA) 23.194229036950972 prot_P38295 + ethanol + propionyl-CoA --> coenzyme A + ethyl propionate 0.0 -r_4680_EXP_2 alcohol acyltransferase (propionyl-CoA) 14.276408471502988 prot_Q02891 + ethanol + propionyl-CoA --> coenzyme A + ethyl propionate 0.0 +r_4680_EXP_2 alcohol acyltransferase (propionyl-CoA) 14.276408471502988 prot_Q02891 + ethanol + propionyl-CoA --> coenzyme A + ethyl propionate 9.25992615918858e-12 r_4680_REV_EXP_1 alcohol acyltransferase (propionyl-CoA) (reversible) 2.0370798777168075 prot_P38295 + coenzyme A + ethyl propionate --> ethanol + propionyl-CoA 0.0 r_4680_REV_EXP_2 alcohol acyltransferase (propionyl-CoA) (reversible) 1.7854367520755017 prot_Q02891 + coenzyme A + ethyl propionate --> ethanol + propionyl-CoA 0.0 r_4681 propionyl-CoA transport, mitochondrial propionyl-CoA --> propionyl-CoA 0.0 -r_4681_REV propionyl-CoA transport, mitochondrial (reversible) propionyl-CoA --> propionyl-CoA 1.9000000606814286e-05 +r_4681_REV propionyl-CoA transport, mitochondrial (reversible) propionyl-CoA --> propionyl-CoA 0.0 r_4682 butyryl-CoA transport, mitochondrial butanoyl-CoA --> butanoyl-CoA 0.0 r_4682_REV butyryl-CoA transport, mitochondrial (reversible) butanoyl-CoA --> butanoyl-CoA 0.0 r_4683 hexanoyl-CoA transport, mitochondrial hexanoyl-CoA --> hexanoyl-CoA 0.0 @@ -6700,7 +6700,7 @@ r_4684 octanoyl-CoA transport, mitochondrial octanoyl-CoA --> octanoyl-CoA 0.0 r_4684_REV octanoyl-CoA transport, mitochondrial (reversible) octanoyl-CoA --> octanoyl-CoA 0.0 r_4685 decanoyl-CoA transport, mitochondrial decanoyl-CoA --> decanoyl-CoA 0.0 r_4685_REV decanoyl-CoA transport, mitochondrial (reversible) decanoyl-CoA --> decanoyl-CoA 0.0 -r_4686 propionate transport, cytosol propionate --> propionate 1.9000000606814286e-05 +r_4686 propionate transport, cytosol propionate --> propionate 0.0 r_4686_REV propionate transport, cytosol (reversible) propionate --> propionate 0.0 r_4687_EXP_1 alcohol acetyltransferase (tyrosol) 0.00442002285061411 prot_P53296 + acetyl-CoA + tyrosol --> coenzyme A + tyrosyl acetate 0.0 r_4687_EXP_2 alcohol acetyltransferase (tyrosol) 0.004358469008854613 prot_P40353 + acetyl-CoA + tyrosol --> coenzyme A + tyrosyl acetate 0.0 @@ -6717,11 +6717,11 @@ r_4693_EXP_2 alcohol acetyltransferase (propanol) 0.004358469008854613 prot_P403 r_4693_EXP_3 alcohol acetyltransferase (propanol) 1.451522803795531 prot_P53208 + acetyl-CoA + propanol --> coenzyme A + propyl acetate 0.0 r_4694 propyl acetate transport propyl acetate --> propyl acetate 0.0 r_4695 propyl acetate exchange propyl acetate --> 0.0 -r_4697 ethyl propionate transport, mitochondrial ethyl propionate --> ethyl propionate 0.0 +r_4697 ethyl propionate transport, mitochondrial ethyl propionate --> ethyl propionate 9.25992615918858e-12 r_4697_REV ethyl propionate transport, mitochondrial (reversible) ethyl propionate --> ethyl propionate 0.0 -r_4698_EXP_1 ethyl propionate transport 1.5359391245241716 prot_P53943 + ethyl propionate --> ethyl propionate 0.0 +r_4698_EXP_1 ethyl propionate transport 1.5359391245241716 prot_P53943 + ethyl propionate --> ethyl propionate 9.25992615918858e-12 r_4698_EXP_2 ethyl propionate transport 52.43332434737383 prot_P36035 + ethyl propionate --> ethyl propionate 0.0 -r_4699 ethyl propionate exchange ethyl propionate --> 0.0 +r_4699 ethyl propionate exchange ethyl propionate --> 9.25992615918858e-12 r_4700 hydrogen sulfide transport 1.563080808080808 prot_P40445 + hydrogen sulfide --> hydrogen sulfide 0.0 r_4701 L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming) 0.011042712066905616 prot_P43623 + H2O + L-cysteine --> ammonium + H+ + pyruvate + hydrogen sulfide 0.0 r_4701_REV L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming) (reversible) 8.086395450568679 prot_P43623 + ammonium + H+ + pyruvate + hydrogen sulfide --> H2O + L-cysteine 0.0 @@ -6741,7 +6741,7 @@ r_4713 diethyl-succinate esterase, c 0.6999026130385602 prot_P41734 + 2.0 H2O + r_4714 monoethyl-succinate esterase, c 1.904471172313294 prot_P41734 + H2O + monoethyl succinate --> ethanol + H+ + succinate 0.0 r_4715 ethyl-benzoate esterase, c 0.6373394427505839 prot_P41734 + ethanol + H+ + Benzoate --> H2O + ethyl benzoate 0.0 r_4715_REV ethyl-benzoate esterase, c (reversible) 0.18097415408676656 prot_P41734 + H2O + ethyl benzoate --> ethanol + H+ + Benzoate 0.0 -r_4716 ethyl-pyruvate esterase, c 0.4678722720909454 prot_P41734 + ethanol + H+ + pyruvate --> H2O + ethyl pyruvate 0.023497347577624478 +r_4716 ethyl-pyruvate esterase, c 0.4678722720909454 prot_P41734 + ethanol + H+ + pyruvate --> H2O + ethyl pyruvate 0.01627913910999937 r_4716_REV ethyl-pyruvate esterase, c (reversible) 0.9013497163220969 prot_P41734 + H2O + ethyl pyruvate --> ethanol + H+ + pyruvate 0.0 r_4717 benzyl-acetate esterase, c 0.49634581652286863 prot_P41734 + acetate + H+ + benzyl alcohol --> H2O + benzyl acetate 0.0 r_4717_REV benzyl-acetate esterase, c (reversible) 0.2685694933176656 prot_P41734 + H2O + benzyl acetate --> acetate + H+ + benzyl alcohol 0.0 @@ -6760,7 +6760,7 @@ r_4721_REV ethyl-2-methylbutyrate esterase, c (reversible) 0.1481119020744172 pr r_4722 polyphosphate polymerase, c 0.6242867867867868 prot_P47075 + 2.0 ATP + H2O --> 2.0 ADP + H+ + polyphosphate 0.0 r_4723_EXP_1 polyphosphate phosphohydrolase, v 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4723_EXP_2 polyphosphate phosphohydrolase, v 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 -r_4724_EXP_1 polyphosphate phosphohydrolase, m 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 4.190212279416091 +r_4724_EXP_1 polyphosphate phosphohydrolase, m 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 2.9878992395213224 r_4724_EXP_2 polyphosphate phosphohydrolase, m 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4725_EXP_1 polyphosphate phosphohydrolase, n 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4725_EXP_2 polyphosphate phosphohydrolase, n 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 @@ -6779,9 +6779,9 @@ r_4733 monoethyl-succinate exchange monoethyl succinate --> 0.0 r_4734 ethyl-benzoate transport ethyl benzoate --> ethyl benzoate 0.0 r_4734_REV ethyl-benzoate transport (reversible) ethyl benzoate --> ethyl benzoate 0.0 r_4735 ethyl-benzoate exchange ethyl benzoate --> 0.0 -r_4736 ethyl-pyruvate transport ethyl pyruvate --> ethyl pyruvate 0.02349734757762448 +r_4736 ethyl-pyruvate transport ethyl pyruvate --> ethyl pyruvate 0.01627913910999937 r_4736_REV ethyl-pyruvate transport (reversible) ethyl pyruvate --> ethyl pyruvate 0.0 -r_4737 ethyl-pyruvate exchange ethyl pyruvate --> 0.02349734757762448 +r_4737 ethyl-pyruvate exchange ethyl pyruvate --> 0.01627913910999937 r_4738 benzyl-acetate transport benzyl acetate --> benzyl acetate 0.0 r_4738_REV benzyl-acetate transport (reversible) benzyl acetate --> benzyl acetate 0.0 r_4739 benzyl-acetate exchange benzyl acetate --> 0.0 @@ -6793,7 +6793,7 @@ r_4742_REV ethyl-2-methylbutyrate transport (reversible) ethyl 2-methylbutyrate r_4743 ethyl-2-methylbutyrate exchange ethyl 2-methylbutyrate --> 0.0 r_4744 polyphosphate transport, v-c H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4744_REV polyphosphate transport, v-c (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 -r_4745 polyphosphate transport, c-m H+ + polyphosphate --> H+ + polyphosphate 4.190212279416092 +r_4745 polyphosphate transport, c-m H+ + polyphosphate --> H+ + polyphosphate 2.9878992395213224 r_4745_REV polyphosphate transport, c-m (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4746 polyphosphate transport, c-n H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4746_REV polyphosphate transport, c-n (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 @@ -6809,8 +6809,8 @@ r_4751_EXP_1 D-phenylalanine N-acetyltransferase 2.211905943882526 prot_P39979 + r_4751_EXP_2 D-phenylalanine N-acetyltransferase 12.731944444444444 prot_Q06592 + acetyl-CoA + D-phenylalanine --> coenzyme A + N-acetyl-D-phenylalanine 0.0 r_4752_EXP_1 S-adenosylmethioninamine:cadaverine 3-aminopropyltransferase 0.4077826725403818 prot_Q12074 + S-adenosylmethioninamine + cadaverine --> 5'-S-methyl-5'-thioadenosine + H+ + aminopropylcadaverine 0.0 r_4752_EXP_2 S-adenosylmethioninamine:cadaverine 3-aminopropyltransferase 0.29592881944444444 prot_Q12455 + S-adenosylmethioninamine + cadaverine --> 5'-S-methyl-5'-thioadenosine + H+ + aminopropylcadaverine 0.0 -r_4753 thiamine phosphate synthase 9.517444068934074 prot_P41835 + 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2.0 H+ + 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate --> carbon dioxide + diphosphate + TMP -5.5491073587190844e-08 -r_4753_REV thiamine phosphate synthase (reversible) 12.363360462224389 prot_P41835 + carbon dioxide + diphosphate + TMP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2.0 H+ + 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate -5.5491073587190844e-08 +r_4753 thiamine phosphate synthase 9.517444068934074 prot_P41835 + 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2.0 H+ + 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate --> carbon dioxide + diphosphate + TMP 0.0 +r_4753_REV thiamine phosphate synthase (reversible) 12.363360462224389 prot_P41835 + carbon dioxide + diphosphate + TMP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2.0 H+ + 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate 0.0 r_4754 flavin prenyltransferase 0.10225155363919607 prot_P33751 + dimethylallyl phosphate + FMNH2 --> phosphate + prenylated FMNH2 0.0 r_4754_REV flavin prenyltransferase (reversible) 2.250252525252525 prot_P33751 + phosphate + prenylated FMNH2 --> dimethylallyl phosphate + FMNH2 0.0 r_4755_EXP_1 (R)-2-hydroxyglutarate:pyruvate oxidoreductase 3.359863945578231 prot_P46681 + pyruvate + 2-hydroxyglutarate --> (R)-lactate + 2-oxoglutarate 0.0 @@ -6846,8 +6846,8 @@ r_4777 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dI r_4777_REV nucleoside diphosphate kinase (reversible) 0.3585421888053467 prot_P36010 + ADP + dITP --> ATP + dIDP 0.0 r_4778 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dUDP --> ADP + dUTP 0.0 r_4778_REV nucleoside diphosphate kinase (reversible) 0.3585421888053467 prot_P36010 + ADP + dUTP --> ATP + dUDP 0.0 -r_4779 heme a transport, cytoplasm-extracellular heme a --> heme a 0.0 -r_4779_REV heme a transport, cytoplasm-extracellular (reversible) heme a --> heme a 9.99999997475243e-08 +r_4779 heme a transport, cytoplasm-extracellular heme a --> heme a -9.99999997475243e-08 +r_4779_REV heme a transport, cytoplasm-extracellular (reversible) heme a --> heme a 0.0 r_4780 heme a exchange heme a --> -9.99999997475243e-08 r_4781 HET-P synthase (thiazole synthase) 0.11030922652440288 prot_P32318 + H2O + ADP-5-ethyl-4-methylthiazole-2-carboxylate --> 4-methyl-5-(2-phosphonooxyethyl)thiazole + AMP + carbon dioxide + H+ 1.20000004244503e-07 r_4782 adenylated thiazole synthase 0.0938740910644444 prot_P32318 + hydrogen sulfide + L-glycine + NAD --> H+ + 3.0 H2O + nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate 1.20000004244503e-07 @@ -6865,56 +6865,56 @@ r_4787_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + H+ + UDP + r_4787_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 r_4787_EXP_4 ribonucleotide reductase 0.9936907838070629 prot_P09938 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 usage_prot_O13525 usage_prot_O13525 prot_pool --> prot_O13525 0.0 -usage_prot_P00044 usage_prot_P00044 prot_pool --> prot_P00044 0.0689925346747622 -usage_prot_P00045 usage_prot_P00045 prot_pool --> prot_P00045 0.06896405972418108 -usage_prot_P00127 usage_prot_P00127 prot_pool --> prot_P00127 0.12253382113382669 -usage_prot_P00128 usage_prot_P00128 prot_pool --> prot_P00128 0.10341919828557603 -usage_prot_P00163 usage_prot_P00163 prot_pool --> prot_P00163 0.30998067424339903 +usage_prot_P00044 usage_prot_P00044 prot_pool --> prot_P00044 0.03347599515291135 +usage_prot_P00045 usage_prot_P00045 prot_pool --> prot_P00045 0.0 +usage_prot_P00127 usage_prot_P00127 prot_pool --> prot_P00127 0.025014118582152016 +usage_prot_P00128 usage_prot_P00128 prot_pool --> prot_P00128 0.02111204943785386 +usage_prot_P00163 usage_prot_P00163 prot_pool --> prot_P00163 0.06327961759416054 usage_prot_P00175 usage_prot_P00175 prot_pool --> prot_P00175 0.0 -usage_prot_P00330 usage_prot_P00330 prot_pool --> prot_P00330 0.0022893996714200573 +usage_prot_P00330 usage_prot_P00330 prot_pool --> prot_P00330 0.0015679084881706554 usage_prot_P00331 usage_prot_P00331 prot_pool --> prot_P00331 0.0 usage_prot_P00358 usage_prot_P00358 prot_pool --> prot_P00358 0.0 usage_prot_P00359 usage_prot_P00359 prot_pool --> prot_P00359 0.0 -usage_prot_P00360 usage_prot_P00360 prot_pool --> prot_P00360 0.354704338234626 -usage_prot_P00401 usage_prot_P00401 prot_pool --> prot_P00401 0.17823988545995265 -usage_prot_P00410 usage_prot_P00410 prot_pool --> prot_P00410 0.08659782319015047 -usage_prot_P00420 usage_prot_P00420 prot_pool --> prot_P00420 0.09203311205422231 -usage_prot_P00424 usage_prot_P00424 prot_pool --> prot_P00424 0.0 +usage_prot_P00360 usage_prot_P00360 prot_pool --> prot_P00360 0.36843801604048587 +usage_prot_P00401 usage_prot_P00401 prot_pool --> prot_P00401 0.0763481924052687 +usage_prot_P00410 usage_prot_P00410 prot_pool --> prot_P00410 0.03709375850269246 +usage_prot_P00420 usage_prot_P00420 prot_pool --> prot_P00420 0.03942193818537974 +usage_prot_P00424 usage_prot_P00424 prot_pool --> prot_P00424 0.02225599540505299 usage_prot_P00425 usage_prot_P00425 prot_pool --> prot_P00425 0.0 -usage_prot_P00427 usage_prot_P00427 prot_pool --> prot_P00427 0.0 +usage_prot_P00427 usage_prot_P00427 prot_pool --> prot_P00427 0.022518288933163884 usage_prot_P00431 usage_prot_P00431 prot_pool --> prot_P00431 0.0 usage_prot_P00445 usage_prot_P00445 prot_pool --> prot_P00445 0.0 usage_prot_P00447 usage_prot_P00447 prot_pool --> prot_P00447 0.0 usage_prot_P00498 usage_prot_P00498 prot_pool --> prot_P00498 0.0069351225554408645 -usage_prot_P00549 usage_prot_P00549 prot_pool --> prot_P00549 0.1490248106924192 -usage_prot_P00560 usage_prot_P00560 prot_pool --> prot_P00560 0.057978571970056694 +usage_prot_P00549 usage_prot_P00549 prot_pool --> prot_P00549 0.15698783774674693 +usage_prot_P00560 usage_prot_P00560 prot_pool --> prot_P00560 0.060223424770683896 usage_prot_P00572 usage_prot_P00572 prot_pool --> prot_P00572 0.0 usage_prot_P00635 usage_prot_P00635 prot_pool --> prot_P00635 0.0 usage_prot_P00724 usage_prot_P00724 prot_pool --> prot_P00724 0.0 usage_prot_P00812 usage_prot_P00812 prot_pool --> prot_P00812 0.0 usage_prot_P00815 usage_prot_P00815 prot_pool --> prot_P00815 0.06105817814264418 -usage_prot_P00817 usage_prot_P00817 prot_pool --> prot_P00817 0.07859099823456481 -usage_prot_P00830 usage_prot_P00830 prot_pool --> prot_P00830 4.57713542575888 -usage_prot_P00854 usage_prot_P00854 prot_pool --> prot_P00854 0.8102472518533514 -usage_prot_P00856 usage_prot_P00856 prot_pool --> prot_P00856 0.1621107082817352 -usage_prot_P00890 usage_prot_P00890 prot_pool --> prot_P00890 0.13317835877212958 -usage_prot_P00899 usage_prot_P00899 prot_pool --> prot_P00899 0.0005100871549319246 -usage_prot_P00912 usage_prot_P00912 prot_pool --> prot_P00912 0.0007103265581898482 -usage_prot_P00924 usage_prot_P00924 prot_pool --> prot_P00924 0.13421566573545698 +usage_prot_P00817 usage_prot_P00817 prot_pool --> prot_P00817 0.04184521851989944 +usage_prot_P00830 usage_prot_P00830 prot_pool --> prot_P00830 0.2574125289112265 +usage_prot_P00854 usage_prot_P00854 prot_pool --> prot_P00854 0.04556731989383132 +usage_prot_P00856 usage_prot_P00856 prot_pool --> prot_P00856 0.009116909049173028 +usage_prot_P00890 usage_prot_P00890 prot_pool --> prot_P00890 0.13225790697429965 +usage_prot_P00899 usage_prot_P00899 prot_pool --> prot_P00899 0.0005100871549317973 +usage_prot_P00912 usage_prot_P00912 prot_pool --> prot_P00912 0.0007103265581897928 +usage_prot_P00924 usage_prot_P00924 prot_pool --> prot_P00924 0.1396972913072295 usage_prot_P00925 usage_prot_P00925 prot_pool --> prot_P00925 0.0 usage_prot_P00927 usage_prot_P00927 prot_pool --> prot_P00927 0.0 -usage_prot_P00931 usage_prot_P00931 prot_pool --> prot_P00931 0.0031547723759833613 -usage_prot_P00937 usage_prot_P00937 prot_pool --> prot_P00937 0.011810009174747095 -usage_prot_P00942 usage_prot_P00942 prot_pool --> prot_P00942 0.0010494213169316275 -usage_prot_P00950 usage_prot_P00950 prot_pool --> prot_P00950 0.03160566516450756 +usage_prot_P00931 usage_prot_P00931 prot_pool --> prot_P00931 0.003154772375983115 +usage_prot_P00937 usage_prot_P00937 prot_pool --> prot_P00937 0.01181000917474609 +usage_prot_P00942 usage_prot_P00942 prot_pool --> prot_P00942 0.0011219905703431978 +usage_prot_P00950 usage_prot_P00950 prot_pool --> prot_P00950 0.03289650123367496 usage_prot_P00958 usage_prot_P00958 prot_pool --> prot_P00958 0.007758377702723959 -usage_prot_P03962 usage_prot_P03962 prot_pool --> prot_P03962 0.00015285215150600333 +usage_prot_P03962 usage_prot_P03962 prot_pool --> prot_P03962 0.00015285215150600336 usage_prot_P03965 usage_prot_P03965 prot_pool --> prot_P03965 0.0 -usage_prot_P04037 usage_prot_P04037 prot_pool --> prot_P04037 0.0 -usage_prot_P04039 usage_prot_P04039 prot_pool --> prot_P04039 0.0 -usage_prot_P04046 usage_prot_P04046 prot_pool --> prot_P04046 0.0029018122709102475 +usage_prot_P04037 usage_prot_P04037 prot_pool --> prot_P04037 0.02225989085349028 +usage_prot_P04039 usage_prot_P04039 prot_pool --> prot_P04039 0.01156558641031546 +usage_prot_P04046 usage_prot_P04046 prot_pool --> prot_P04046 0.0029018122709102423 usage_prot_P04076 usage_prot_P04076 prot_pool --> prot_P04076 9.576474603701102e-05 -usage_prot_P04161 usage_prot_P04161 prot_pool --> prot_P04161 0.0016740252577010497 +usage_prot_P04161 usage_prot_P04161 prot_pool --> prot_P04161 0.0016740252577010467 usage_prot_P04173 usage_prot_P04173 prot_pool --> prot_P04173 0.002406504749325647 usage_prot_P04385 usage_prot_P04385 prot_pool --> prot_P04385 0.0 usage_prot_P04397 usage_prot_P04397 prot_pool --> prot_P04397 0.0 @@ -6929,17 +6929,17 @@ usage_prot_P05030 usage_prot_P05030 prot_pool --> prot_P05030 0.0 usage_prot_P05150 usage_prot_P05150 prot_pool --> prot_P05150 6.007467226861394e-05 usage_prot_P05316 usage_prot_P05316 prot_pool --> prot_P05316 0.0 usage_prot_P05373 usage_prot_P05373 prot_pool --> prot_P05373 0.0 -usage_prot_P05374 usage_prot_P05374 prot_pool --> prot_P05374 0.5802740778505086 -usage_prot_P05375 usage_prot_P05375 prot_pool --> prot_P05375 0.008359552738834127 -usage_prot_P05626 usage_prot_P05626 prot_pool --> prot_P05626 0.7497132979192236 -usage_prot_P05694 usage_prot_P05694 prot_pool --> prot_P05694 0.5348758835341649 -usage_prot_P06106 usage_prot_P06106 prot_pool --> prot_P06106 0.0016681143322862363 -usage_prot_P06115 usage_prot_P06115 prot_pool --> prot_P06115 0.0 -usage_prot_P06168 usage_prot_P06168 prot_pool --> prot_P06168 0.07043986489974646 -usage_prot_P06169 usage_prot_P06169 prot_pool --> prot_P06169 0.1472923730282787 +usage_prot_P05374 usage_prot_P05374 prot_pool --> prot_P05374 0.5802740778505087 +usage_prot_P05375 usage_prot_P05375 prot_pool --> prot_P05375 0.008359552738834108 +usage_prot_P05626 usage_prot_P05626 prot_pool --> prot_P05626 0.04216296395551079 +usage_prot_P05694 usage_prot_P05694 prot_pool --> prot_P05694 0.5348758835341646 +usage_prot_P06106 usage_prot_P06106 prot_pool --> prot_P06106 0.0016681143322862578 +usage_prot_P06115 usage_prot_P06115 prot_pool --> prot_P06115 7.729761954238344e-09 +usage_prot_P06168 usage_prot_P06168 prot_pool --> prot_P06168 0.06349501004238978 +usage_prot_P06169 usage_prot_P06169 prot_pool --> prot_P06169 0.08678822724070781 usage_prot_P06174 usage_prot_P06174 prot_pool --> prot_P06174 0.0 usage_prot_P06182 usage_prot_P06182 prot_pool --> prot_P06182 0.0 -usage_prot_P06197 usage_prot_P06197 prot_pool --> prot_P06197 0.0009015544945121599 +usage_prot_P06197 usage_prot_P06197 prot_pool --> prot_P06197 0.0009015544945121608 usage_prot_P06208 usage_prot_P06208 prot_pool --> prot_P06208 0.049955394439387076 usage_prot_P06633 usage_prot_P06633 prot_pool --> prot_P06633 3.951695237200766e-05 usage_prot_P06700 usage_prot_P06700 prot_pool --> prot_P06700 0.0 @@ -6949,31 +6949,31 @@ usage_prot_P06775 usage_prot_P06775 prot_pool --> prot_P06775 0.0002071093245123 usage_prot_P06776 usage_prot_P06776 prot_pool --> prot_P06776 0.0 usage_prot_P06780 usage_prot_P06780 prot_pool --> prot_P06780 0.0914294990677141 usage_prot_P06785 usage_prot_P06785 prot_pool --> prot_P06785 7.30145820791087e-05 -usage_prot_P07143 usage_prot_P07143 prot_pool --> prot_P07143 0.24180849966462695 -usage_prot_P07149 usage_prot_P07149 prot_pool --> prot_P07149 0.4539338997772454 -usage_prot_P07170 usage_prot_P07170 prot_pool --> prot_P07170 0.004229187151423634 +usage_prot_P07143 usage_prot_P07143 prot_pool --> prot_P07143 0.049362914082122435 +usage_prot_P07149 usage_prot_P07149 prot_pool --> prot_P07149 0.45340731642373533 +usage_prot_P07170 usage_prot_P07170 prot_pool --> prot_P07170 0.004673024547500429 usage_prot_P07172 usage_prot_P07172 prot_pool --> prot_P07172 3.193370984930483e-05 usage_prot_P07236 usage_prot_P07236 prot_pool --> prot_P07236 0.0 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0.011789105063252862 +usage_prot_P32178 usage_prot_P32178 prot_pool --> prot_P32178 0.0006633828635753931 +usage_prot_P32179 usage_prot_P32179 prot_pool --> prot_P32179 0.011789105063253013 usage_prot_P32190 usage_prot_P32190 prot_pool --> prot_P32190 0.0 usage_prot_P32191 usage_prot_P32191 prot_pool --> prot_P32191 0.0 usage_prot_P32263 usage_prot_P32263 prot_pool --> prot_P32263 0.00018191026059516946 usage_prot_P32264 usage_prot_P32264 prot_pool --> prot_P32264 0.08897571218087687 -usage_prot_P32288 usage_prot_P32288 prot_pool --> prot_P32288 0.003061407963508187 +usage_prot_P32288 usage_prot_P32288 prot_pool --> prot_P32288 0.0030614079635081204 usage_prot_P32316 usage_prot_P32316 prot_pool --> prot_P32316 0.40286238046871475 usage_prot_P32318 usage_prot_P32318 prot_pool --> prot_P32318 2.4501998977318376e-08 usage_prot_P32327 usage_prot_P32327 prot_pool --> prot_P32327 0.0 -usage_prot_P32331 usage_prot_P32331 prot_pool --> prot_P32331 0.00015754712346761616 +usage_prot_P32331 usage_prot_P32331 prot_pool --> prot_P32331 0.00015754712346887118 usage_prot_P32332 usage_prot_P32332 prot_pool --> prot_P32332 0.02284632463430561 -usage_prot_P32340 usage_prot_P32340 prot_pool --> prot_P32340 0.12016608008615588 +usage_prot_P32340 usage_prot_P32340 prot_pool --> prot_P32340 0.1170711250817337 usage_prot_P32347 usage_prot_P32347 prot_pool --> prot_P32347 0.0 -usage_prot_P32352 usage_prot_P32352 prot_pool --> prot_P32352 0.005581109843713914 -usage_prot_P32353 usage_prot_P32353 prot_pool --> prot_P32353 0.012455427258248707 +usage_prot_P32352 usage_prot_P32352 prot_pool --> prot_P32352 0.0 +usage_prot_P32353 usage_prot_P32353 prot_pool --> prot_P32353 0.0 usage_prot_P32356 usage_prot_P32356 prot_pool --> prot_P32356 0.0 usage_prot_P32363 usage_prot_P32363 prot_pool --> prot_P32363 0.0 usage_prot_P32366 usage_prot_P32366 prot_pool --> prot_P32366 0.0 usage_prot_P32368 usage_prot_P32368 prot_pool --> prot_P32368 0.0 usage_prot_P32375 usage_prot_P32375 prot_pool --> prot_P32375 0.0 -usage_prot_P32377 usage_prot_P32377 prot_pool --> prot_P32377 0.05588958020418285 +usage_prot_P32377 usage_prot_P32377 prot_pool --> prot_P32377 0.05588958020415754 usage_prot_P32378 usage_prot_P32378 prot_pool --> prot_P32378 0.0 usage_prot_P32383 usage_prot_P32383 prot_pool --> prot_P32383 0.0 usage_prot_P32386 usage_prot_P32386 prot_pool --> prot_P32386 0.0 -usage_prot_P32419 usage_prot_P32419 prot_pool --> prot_P32419 1.3158875215637873e-08 -usage_prot_P32449 usage_prot_P32449 prot_pool --> prot_P32449 0.004158005680045069 +usage_prot_P32419 usage_prot_P32419 prot_pool --> prot_P32419 0.0 +usage_prot_P32449 usage_prot_P32449 prot_pool --> prot_P32449 0.003027556374552756 usage_prot_P32451 usage_prot_P32451 prot_pool --> prot_P32451 0.0 -usage_prot_P32452 usage_prot_P32452 prot_pool --> prot_P32452 0.00021574476169689295 +usage_prot_P32452 usage_prot_P32452 prot_pool --> prot_P32452 0.00021574476169689292 usage_prot_P32459 usage_prot_P32459 prot_pool --> prot_P32459 0.0 -usage_prot_P32462 usage_prot_P32462 prot_pool --> prot_P32462 0.015622718902902387 +usage_prot_P32462 usage_prot_P32462 prot_pool --> prot_P32462 0.015622718902895313 usage_prot_P32463 usage_prot_P32463 prot_pool --> prot_P32463 0.0 usage_prot_P32465 usage_prot_P32465 prot_pool --> prot_P32465 0.0 usage_prot_P32466 usage_prot_P32466 prot_pool --> prot_P32466 2.0793628830928714 usage_prot_P32467 usage_prot_P32467 prot_pool --> prot_P32467 0.0 usage_prot_P32469 usage_prot_P32469 prot_pool --> prot_P32469 0.0 -usage_prot_P32473 usage_prot_P32473 prot_pool --> prot_P32473 0.046662430536250826 -usage_prot_P32476 usage_prot_P32476 prot_pool --> prot_P32476 0.6002879186423049 -usage_prot_P32477 usage_prot_P32477 prot_pool --> prot_P32477 2.1331915821484914e-10 +usage_prot_P32473 usage_prot_P32473 prot_pool --> prot_P32473 0.3563439150007834 +usage_prot_P32476 usage_prot_P32476 prot_pool --> prot_P32476 0.6002879186420331 +usage_prot_P32477 usage_prot_P32477 prot_pool --> prot_P32477 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usage_prot_P32837 prot_pool --> prot_P32837 0.0 usage_prot_P32842 usage_prot_P32842 prot_pool --> prot_P32842 0.0 usage_prot_P32861 usage_prot_P32861 prot_pool --> prot_P32861 0.0 usage_prot_P32874 usage_prot_P32874 prot_pool --> prot_P32874 0.0 -usage_prot_P32891 usage_prot_P32891 prot_pool --> prot_P32891 0.10501347129528892 -usage_prot_P32895 usage_prot_P32895 prot_pool --> prot_P32895 0.005828306386229404 +usage_prot_P32891 usage_prot_P32891 prot_pool --> prot_P32891 0.0 +usage_prot_P32895 usage_prot_P32895 prot_pool --> prot_P32895 0.005828306386229144 usage_prot_P32901 usage_prot_P32901 prot_pool --> prot_P32901 0.0 usage_prot_P32903 usage_prot_P32903 prot_pool --> prot_P32903 0.0 usage_prot_P32906 usage_prot_P32906 prot_pool --> prot_P32906 0.0 usage_prot_P33300 usage_prot_P33300 prot_pool --> prot_P33300 0.0 -usage_prot_P33303 usage_prot_P33303 prot_pool --> prot_P33303 0.007632871718103308 -usage_prot_P33312 usage_prot_P33312 prot_pool --> prot_P33312 5.311659714204637e-05 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prot_pool --> prot_P33421 0.02837705947860703 usage_prot_P33550 usage_prot_P33550 prot_pool --> prot_P33550 0.0 usage_prot_P33734 usage_prot_P33734 prot_pool --> prot_P33734 0.020544584974038976 usage_prot_P33751 usage_prot_P33751 prot_pool --> prot_P33751 0.0 @@ -7324,7 +7324,7 @@ usage_prot_P33775 usage_prot_P33775 prot_pool --> prot_P33775 0.0 usage_prot_P33893 usage_prot_P33893 prot_pool --> prot_P33893 0.0 usage_prot_P34163 usage_prot_P34163 prot_pool --> prot_P34163 0.0 usage_prot_P34227 usage_prot_P34227 prot_pool --> prot_P34227 0.0 -usage_prot_P34230 usage_prot_P34230 prot_pool --> prot_P34230 0.0006356191394343596 +usage_prot_P34230 usage_prot_P34230 prot_pool --> prot_P34230 0.0 usage_prot_P34756 usage_prot_P34756 prot_pool --> prot_P34756 0.0 usage_prot_P35172 usage_prot_P35172 prot_pool --> prot_P35172 0.0 usage_prot_P35196 usage_prot_P35196 prot_pool --> prot_P35196 0.0 @@ -7335,20 +7335,20 @@ usage_prot_P35731 usage_prot_P35731 prot_pool --> prot_P35731 0.0 usage_prot_P35842 usage_prot_P35842 prot_pool --> prot_P35842 0.0 usage_prot_P36001 usage_prot_P36001 prot_pool --> prot_P36001 0.0 usage_prot_P36007 usage_prot_P36007 prot_pool --> prot_P36007 0.0 -usage_prot_P36010 usage_prot_P36010 prot_pool --> prot_P36010 0.008701390748042815 -usage_prot_P36013 usage_prot_P36013 prot_pool --> prot_P36013 0.0007627054629676683 +usage_prot_P36010 usage_prot_P36010 prot_pool --> prot_P36010 0.006364776931411873 +usage_prot_P36013 usage_prot_P36013 prot_pool --> prot_P36013 0.002688512345282201 usage_prot_P36014 usage_prot_P36014 prot_pool --> prot_P36014 0.0 -usage_prot_P36024 usage_prot_P36024 prot_pool --> prot_P36024 0.0001137051760729301 +usage_prot_P36024 usage_prot_P36024 prot_pool --> prot_P36024 0.00011370517607383587 usage_prot_P36029 usage_prot_P36029 prot_pool --> prot_P36029 0.0 usage_prot_P36033 usage_prot_P36033 prot_pool --> prot_P36033 0.0 usage_prot_P36035 usage_prot_P36035 prot_pool --> prot_P36035 0.0 usage_prot_P36051 usage_prot_P36051 prot_pool --> prot_P36051 0.0 usage_prot_P36060 usage_prot_P36060 prot_pool --> prot_P36060 0.0 usage_prot_P36062 usage_prot_P36062 prot_pool --> prot_P36062 0.0 -usage_prot_P36076 usage_prot_P36076 prot_pool --> prot_P36076 0.00011872816474032161 +usage_prot_P36076 usage_prot_P36076 prot_pool --> prot_P36076 0.0001187281647412674 usage_prot_P36088 usage_prot_P36088 prot_pool --> prot_P36088 0.0 usage_prot_P36107 usage_prot_P36107 prot_pool --> prot_P36107 0.0 -usage_prot_P36126 usage_prot_P36126 prot_pool --> prot_P36126 4.6084632672297e-05 +usage_prot_P36126 usage_prot_P36126 prot_pool --> prot_P36126 4.608463267229687e-05 usage_prot_P36136 usage_prot_P36136 prot_pool --> prot_P36136 0.0 usage_prot_P36143 usage_prot_P36143 prot_pool --> prot_P36143 0.0 usage_prot_P36148 usage_prot_P36148 prot_pool --> prot_P36148 0.06774500591547604 @@ -7360,31 +7360,31 @@ usage_prot_P36973 usage_prot_P36973 prot_pool --> prot_P36973 0.0 usage_prot_P37012 usage_prot_P37012 prot_pool --> prot_P37012 0.012258563367983833 usage_prot_P37020 usage_prot_P37020 prot_pool --> prot_P37020 0.0 usage_prot_P37254 usage_prot_P37254 prot_pool --> prot_P37254 0.009172695793144503 -usage_prot_P37291 usage_prot_P37291 prot_pool --> prot_P37291 0.0019508363682404551 +usage_prot_P37291 usage_prot_P37291 prot_pool --> prot_P37291 0.0019508363682405052 usage_prot_P37292 usage_prot_P37292 prot_pool --> prot_P37292 0.0 usage_prot_P37296 usage_prot_P37296 prot_pool --> prot_P37296 0.0 usage_prot_P37297 usage_prot_P37297 prot_pool --> prot_P37297 0.0 usage_prot_P37298 usage_prot_P37298 prot_pool --> prot_P37298 0.0 -usage_prot_P37299 usage_prot_P37299 prot_pool --> prot_P37299 0.061014841803498435 +usage_prot_P37299 usage_prot_P37299 prot_pool --> prot_P37299 0.012455601841364794 usage_prot_P37303 usage_prot_P37303 prot_pool --> prot_P37303 0.0 -usage_prot_P38009 usage_prot_P38009 prot_pool --> prot_P38009 0.07840419894300928 -usage_prot_P38013 usage_prot_P38013 prot_pool --> prot_P38013 4.3290597493149975e-05 +usage_prot_P38009 usage_prot_P38009 prot_pool --> prot_P38009 0.07840419894300918 +usage_prot_P38013 usage_prot_P38013 prot_pool --> prot_P38013 0.0 usage_prot_P38063 usage_prot_P38063 prot_pool --> prot_P38063 0.0 -usage_prot_P38066 usage_prot_P38066 prot_pool --> prot_P38066 2.464763303253681e-06 +usage_prot_P38066 usage_prot_P38066 prot_pool --> prot_P38066 2.464763303253647e-06 usage_prot_P38067 usage_prot_P38067 prot_pool --> prot_P38067 0.0015079031745331318 usage_prot_P38071 usage_prot_P38071 prot_pool --> prot_P38071 0.0 usage_prot_P38074 usage_prot_P38074 prot_pool --> prot_P38074 0.0 -usage_prot_P38075 usage_prot_P38075 prot_pool --> prot_P38075 0.07340047937193524 -usage_prot_P38077 usage_prot_P38077 prot_pool --> prot_P38077 0.9564865922682732 +usage_prot_P38075 usage_prot_P38075 prot_pool --> prot_P38075 0.0 +usage_prot_P38077 usage_prot_P38077 prot_pool --> prot_P38077 0.05379164251943365 usage_prot_P38084 usage_prot_P38084 prot_pool --> prot_P38084 0.0 usage_prot_P38085 usage_prot_P38085 prot_pool --> prot_P38085 0.0 usage_prot_P38088 usage_prot_P38088 prot_pool --> prot_P38088 0.0 usage_prot_P38090 usage_prot_P38090 prot_pool --> prot_P38090 0.0 -usage_prot_P38113 usage_prot_P38113 prot_pool --> prot_P38113 6.552931858378057e-05 +usage_prot_P38113 usage_prot_P38113 prot_pool --> prot_P38113 0.0 usage_prot_P38115 usage_prot_P38115 prot_pool --> prot_P38115 0.0 -usage_prot_P38122 usage_prot_P38122 prot_pool --> prot_P38122 0.00023230985563828306 +usage_prot_P38122 usage_prot_P38122 prot_pool --> prot_P38122 0.00023230985564013366 usage_prot_P38125 usage_prot_P38125 prot_pool --> prot_P38125 0.0 -usage_prot_P38127 usage_prot_P38127 prot_pool --> prot_P38127 0.06989336281664138 +usage_prot_P38127 usage_prot_P38127 prot_pool --> prot_P38127 0.0 usage_prot_P38130 usage_prot_P38130 prot_pool --> prot_P38130 0.0 usage_prot_P38131 usage_prot_P38131 prot_pool --> prot_P38131 0.0 usage_prot_P38137 usage_prot_P38137 prot_pool --> prot_P38137 0.0 @@ -7392,24 +7392,24 @@ usage_prot_P38138 usage_prot_P38138 prot_pool --> prot_P38138 0.0 usage_prot_P38139 usage_prot_P38139 prot_pool --> prot_P38139 0.0 usage_prot_P38142 usage_prot_P38142 prot_pool --> prot_P38142 0.0 usage_prot_P38143 usage_prot_P38143 prot_pool --> prot_P38143 0.0 -usage_prot_P38145 usage_prot_P38145 prot_pool --> prot_P38145 0.005450686484172471 +usage_prot_P38145 usage_prot_P38145 prot_pool --> prot_P38145 0.0054506864841723955 usage_prot_P38149 usage_prot_P38149 prot_pool --> prot_P38149 0.0 -usage_prot_P38152 usage_prot_P38152 prot_pool --> prot_P38152 0.08184299963218877 +usage_prot_P38152 usage_prot_P38152 prot_pool --> prot_P38152 0.12022827033173503 usage_prot_P38156 usage_prot_P38156 prot_pool --> prot_P38156 0.0 usage_prot_P38158 usage_prot_P38158 prot_pool --> prot_P38158 0.0 -usage_prot_P38169 usage_prot_P38169 prot_pool --> prot_P38169 0.004354734929349467 +usage_prot_P38169 usage_prot_P38169 prot_pool --> prot_P38169 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0.02999042102416425 +usage_prot_P38286 usage_prot_P38286 prot_pool --> prot_P38286 0.029821986970047027 usage_prot_P38287 usage_prot_P38287 prot_pool --> prot_P38287 0.0 usage_prot_P38295 usage_prot_P38295 prot_pool --> prot_P38295 0.0 usage_prot_P38298 usage_prot_P38298 prot_pool --> prot_P38298 0.0 @@ -7417,16 +7417,16 @@ usage_prot_P38329 usage_prot_P38329 prot_pool --> prot_P38329 0.0 usage_prot_P38331 usage_prot_P38331 prot_pool --> prot_P38331 0.0 usage_prot_P38342 usage_prot_P38342 prot_pool --> prot_P38342 0.0 usage_prot_P38358 usage_prot_P38358 prot_pool --> prot_P38358 0.0 -usage_prot_P38359 usage_prot_P38359 prot_pool --> prot_P38359 0.03374014317423503 +usage_prot_P38359 usage_prot_P38359 prot_pool --> prot_P38359 0.0337401431742354 usage_prot_P38360 usage_prot_P38360 prot_pool --> prot_P38360 0.0 -usage_prot_P38361 usage_prot_P38361 prot_pool --> prot_P38361 0.044162628609076965 +usage_prot_P38361 usage_prot_P38361 prot_pool --> prot_P38361 0.04416262860910464 usage_prot_P38426 usage_prot_P38426 prot_pool --> prot_P38426 0.028198896311191803 usage_prot_P38427 usage_prot_P38427 prot_pool --> prot_P38427 0.0 -usage_prot_P38604 usage_prot_P38604 prot_pool --> prot_P38604 0.0910520333041449 -usage_prot_P38620 usage_prot_P38620 prot_pool --> prot_P38620 0.004306779848178741 -usage_prot_P38625 usage_prot_P38625 prot_pool --> prot_P38625 4.705680621726141e-05 -usage_prot_P38626 usage_prot_P38626 prot_pool --> prot_P38626 8.886606334186752e-05 -usage_prot_P38627 usage_prot_P38627 prot_pool --> prot_P38627 0.002768076862935347 +usage_prot_P38604 usage_prot_P38604 prot_pool --> prot_P38604 0.09105203330410366 +usage_prot_P38620 usage_prot_P38620 prot_pool --> prot_P38620 0.004306779848178549 +usage_prot_P38625 usage_prot_P38625 prot_pool --> prot_P38625 4.7056806217261684e-05 +usage_prot_P38626 usage_prot_P38626 prot_pool --> prot_P38626 8.886606334182728e-05 +usage_prot_P38627 usage_prot_P38627 prot_pool --> prot_P38627 0.002768076862935344 usage_prot_P38628 usage_prot_P38628 prot_pool --> prot_P38628 0.0010068169057630475 usage_prot_P38631 usage_prot_P38631 prot_pool --> prot_P38631 0.0 usage_prot_P38635 usage_prot_P38635 prot_pool --> prot_P38635 4.185079666463251e-05 @@ -7434,8 +7434,8 @@ usage_prot_P38689 usage_prot_P38689 prot_pool --> prot_P38689 0.0 usage_prot_P38693 usage_prot_P38693 prot_pool --> prot_P38693 0.0 usage_prot_P38695 usage_prot_P38695 prot_pool --> prot_P38695 0.0 usage_prot_P38697 usage_prot_P38697 prot_pool --> prot_P38697 0.0 -usage_prot_P38698 usage_prot_P38698 prot_pool --> prot_P38698 0.06323603115175994 -usage_prot_P38702 usage_prot_P38702 prot_pool --> prot_P38702 0.003848374738838978 +usage_prot_P38698 usage_prot_P38698 prot_pool --> prot_P38698 0.040445538265238515 +usage_prot_P38702 usage_prot_P38702 prot_pool --> prot_P38702 0.00384492772158554 usage_prot_P38703 usage_prot_P38703 prot_pool --> prot_P38703 0.0 usage_prot_P38705 usage_prot_P38705 prot_pool --> prot_P38705 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9.039989179876055e-06 usage_prot_P38790 usage_prot_P38790 prot_pool --> prot_P38790 0.0 usage_prot_P38791 usage_prot_P38791 prot_pool --> prot_P38791 0.0 -usage_prot_P38795 usage_prot_P38795 prot_pool --> prot_P38795 0.0021261321228542044 -usage_prot_P38812 usage_prot_P38812 prot_pool --> prot_P38812 0.015755228140289446 +usage_prot_P38795 usage_prot_P38795 prot_pool --> prot_P38795 0.0021261321228503017 +usage_prot_P38812 usage_prot_P38812 prot_pool --> prot_P38812 0.0 usage_prot_P38816 usage_prot_P38816 prot_pool --> prot_P38816 0.0 usage_prot_P38818 usage_prot_P38818 prot_pool --> prot_P38818 0.0 -usage_prot_P38824 usage_prot_P38824 prot_pool --> prot_P38824 0.05249767570998095 -usage_prot_P38840 usage_prot_P38840 prot_pool --> prot_P38840 0.0026360564914748212 +usage_prot_P38824 usage_prot_P38824 prot_pool --> prot_P38824 0.0 +usage_prot_P38840 usage_prot_P38840 prot_pool --> prot_P38840 0.002636056491474855 usage_prot_P38857 usage_prot_P38857 prot_pool --> prot_P38857 0.0 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1.1527012652806743 usage_prot_P38986 usage_prot_P38986 prot_pool --> prot_P38986 0.0 -usage_prot_P38988 usage_prot_P38988 prot_pool --> prot_P38988 0.11029491388672448 +usage_prot_P38988 usage_prot_P38988 prot_pool --> prot_P38988 0.09418705527228925 usage_prot_P38992 usage_prot_P38992 prot_pool --> prot_P38992 0.0 usage_prot_P38993 usage_prot_P38993 prot_pool --> prot_P38993 0.0 usage_prot_P38994 usage_prot_P38994 prot_pool --> prot_P38994 0.0 @@ -7480,37 +7480,37 @@ usage_prot_P38999 usage_prot_P38999 prot_pool --> prot_P38999 0.0072577135644597 usage_prot_P39002 usage_prot_P39002 prot_pool --> prot_P39002 0.0 usage_prot_P39003 usage_prot_P39003 prot_pool --> prot_P39003 0.0 usage_prot_P39004 usage_prot_P39004 prot_pool --> prot_P39004 0.0 -usage_prot_P39006 usage_prot_P39006 prot_pool --> prot_P39006 0.00018910264068612372 +usage_prot_P39006 usage_prot_P39006 prot_pool --> prot_P39006 0.0001891026406861234 usage_prot_P39104 usage_prot_P39104 prot_pool --> prot_P39104 0.0 usage_prot_P39105 usage_prot_P39105 prot_pool --> prot_P39105 0.0 usage_prot_P39109 usage_prot_P39109 prot_pool --> prot_P39109 0.0 usage_prot_P39111 usage_prot_P39111 prot_pool --> prot_P39111 0.0 -usage_prot_P39518 usage_prot_P39518 prot_pool --> prot_P39518 0.021268016171521305 -usage_prot_P39522 usage_prot_P39522 prot_pool --> prot_P39522 0.06793176582798652 +usage_prot_P39518 usage_prot_P39518 prot_pool --> prot_P39518 0.0 +usage_prot_P39522 usage_prot_P39522 prot_pool --> prot_P39522 0.05329245657385118 usage_prot_P39524 usage_prot_P39524 prot_pool --> prot_P39524 0.0 usage_prot_P39525 usage_prot_P39525 prot_pool --> prot_P39525 0.0 usage_prot_P39533 usage_prot_P39533 prot_pool --> prot_P39533 0.1509840990781967 usage_prot_P39535 usage_prot_P39535 prot_pool --> prot_P39535 0.0 -usage_prot_P39540 usage_prot_P39540 prot_pool --> prot_P39540 5.333624367626592e-06 +usage_prot_P39540 usage_prot_P39540 prot_pool --> prot_P39540 0.0 usage_prot_P39676 usage_prot_P39676 prot_pool --> prot_P39676 0.0 usage_prot_P39683 usage_prot_P39683 prot_pool --> prot_P39683 7.5112222489234e-06 -usage_prot_P39692 usage_prot_P39692 prot_pool --> prot_P39692 0.004876517983689825 +usage_prot_P39692 usage_prot_P39692 prot_pool --> prot_P39692 0.004876517983689888 usage_prot_P39708 usage_prot_P39708 prot_pool --> prot_P39708 0.0 usage_prot_P39713 usage_prot_P39713 prot_pool --> prot_P39713 0.0 usage_prot_P39714 usage_prot_P39714 prot_pool --> prot_P39714 0.0 -usage_prot_P39726 usage_prot_P39726 prot_pool --> prot_P39726 0.0065041242857872255 +usage_prot_P39726 usage_prot_P39726 prot_pool --> prot_P39726 0.11708012788037957 usage_prot_P39730 usage_prot_P39730 prot_pool --> prot_P39730 0.0 usage_prot_P39924 usage_prot_P39924 prot_pool --> prot_P39924 0.0 usage_prot_P39932 usage_prot_P39932 prot_pool --> prot_P39932 0.0 usage_prot_P39953 usage_prot_P39953 prot_pool --> prot_P39953 0.0 -usage_prot_P39954 usage_prot_P39954 prot_pool --> prot_P39954 0.000330611623162962 +usage_prot_P39954 usage_prot_P39954 prot_pool --> prot_P39954 0.00033061162316296185 usage_prot_P39965 usage_prot_P39965 prot_pool --> prot_P39965 0.0 -usage_prot_P39976 usage_prot_P39976 prot_pool --> prot_P39976 0.09858168253489627 +usage_prot_P39976 usage_prot_P39976 prot_pool --> prot_P39976 0.0 usage_prot_P39979 usage_prot_P39979 prot_pool --> prot_P39979 0.0 usage_prot_P39986 usage_prot_P39986 prot_pool --> prot_P39986 0.0 usage_prot_P39988 usage_prot_P39988 prot_pool --> prot_P39988 0.0 usage_prot_P40004 usage_prot_P40004 prot_pool --> prot_P40004 0.0 -usage_prot_P40009 usage_prot_P40009 prot_pool --> prot_P40009 0.01292543749947245 +usage_prot_P40009 usage_prot_P40009 prot_pool --> prot_P40009 0.015117064211493916 usage_prot_P40011 usage_prot_P40011 prot_pool --> prot_P40011 0.0 usage_prot_P40012 usage_prot_P40012 prot_pool --> prot_P40012 0.0 usage_prot_P40015 usage_prot_P40015 prot_pool --> prot_P40015 0.0 @@ -7523,39 +7523,39 @@ usage_prot_P40047 usage_prot_P40047 prot_pool --> prot_P40047 0.0 usage_prot_P40054 usage_prot_P40054 prot_pool --> prot_P40054 0.0 usage_prot_P40074 usage_prot_P40074 prot_pool --> prot_P40074 0.0 usage_prot_P40086 usage_prot_P40086 prot_pool --> prot_P40086 0.0 -usage_prot_P40099 usage_prot_P40099 prot_pool --> prot_P40099 0.0 +usage_prot_P40099 usage_prot_P40099 prot_pool --> prot_P40099 17.099047167245722 usage_prot_P40106 usage_prot_P40106 prot_pool --> prot_P40106 0.0 usage_prot_P40107 usage_prot_P40107 prot_pool --> prot_P40107 0.0 -usage_prot_P40215 usage_prot_P40215 prot_pool --> prot_P40215 0.0564472572223587 +usage_prot_P40215 usage_prot_P40215 prot_pool --> prot_P40215 0.06508640750602056 usage_prot_P40260 usage_prot_P40260 prot_pool --> prot_P40260 0.0 usage_prot_P40308 usage_prot_P40308 prot_pool --> prot_P40308 0.0 usage_prot_P40319 usage_prot_P40319 prot_pool --> prot_P40319 0.0 -usage_prot_P40345 usage_prot_P40345 prot_pool --> prot_P40345 0.9408958319832066 +usage_prot_P40345 usage_prot_P40345 prot_pool --> prot_P40345 0.0 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usage_prot_P40559 prot_pool --> prot_P40559 0.0 usage_prot_P40580 usage_prot_P40580 prot_pool --> prot_P40580 0.0 usage_prot_P40581 usage_prot_P40581 prot_pool --> prot_P40581 0.0 usage_prot_P40825 usage_prot_P40825 prot_pool --> prot_P40825 0.008859154130962155 -usage_prot_P40857 usage_prot_P40857 prot_pool --> prot_P40857 0.0035484086387397333 +usage_prot_P40857 usage_prot_P40857 prot_pool --> prot_P40857 0.0035284798470696876 usage_prot_P40884 usage_prot_P40884 prot_pool --> prot_P40884 0.0 usage_prot_P40885 usage_prot_P40885 prot_pool --> prot_P40885 0.0 usage_prot_P40886 usage_prot_P40886 prot_pool --> prot_P40886 0.0 @@ -7565,18 +7565,18 @@ usage_prot_P40975 usage_prot_P40975 prot_pool --> prot_P40975 0.0 usage_prot_P40988 usage_prot_P40988 prot_pool --> prot_P40988 2.4101980169772022e-05 usage_prot_P40989 usage_prot_P40989 prot_pool --> prot_P40989 0.0 usage_prot_P41277 usage_prot_P41277 prot_pool --> prot_P41277 0.0 -usage_prot_P41338 usage_prot_P41338 prot_pool --> prot_P41338 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usage_prot_P52910 prot_pool --> prot_P52910 0.12518701977168165 usage_prot_P52911 usage_prot_P52911 prot_pool --> prot_P52911 0.0 usage_prot_P53008 usage_prot_P53008 prot_pool --> prot_P53008 0.0 usage_prot_P53037 usage_prot_P53037 prot_pool --> prot_P53037 0.0 -usage_prot_P53045 usage_prot_P53045 prot_pool --> prot_P53045 0.007624603686176521 +usage_prot_P53045 usage_prot_P53045 prot_pool --> prot_P53045 0.007624603686173068 usage_prot_P53048 usage_prot_P53048 prot_pool --> prot_P53048 0.0 usage_prot_P53051 usage_prot_P53051 prot_pool --> prot_P53051 0.0 usage_prot_P53078 usage_prot_P53078 prot_pool --> prot_P53078 0.0 -usage_prot_P53090 usage_prot_P53090 prot_pool --> prot_P53090 0.03318704605389991 +usage_prot_P53090 usage_prot_P53090 prot_pool --> prot_P53090 0.03318704605390023 usage_prot_P53095 usage_prot_P53095 prot_pool --> prot_P53095 0.0 usage_prot_P53099 usage_prot_P53099 prot_pool --> prot_P53099 0.0 usage_prot_P53101 usage_prot_P53101 prot_pool --> prot_P53101 0.0 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0.00014051304866717317 usage_prot_P53206 usage_prot_P53206 prot_pool --> prot_P53206 0.0 usage_prot_P53208 usage_prot_P53208 prot_pool --> prot_P53208 0.0 usage_prot_P53223 usage_prot_P53223 prot_pool --> prot_P53223 0.0 usage_prot_P53224 usage_prot_P53224 prot_pool --> prot_P53224 0.0 usage_prot_P53228 usage_prot_P53228 prot_pool --> prot_P53228 0.0 -usage_prot_P53230 usage_prot_P53230 prot_pool --> prot_P53230 0.08945672368063616 -usage_prot_P53239 usage_prot_P53239 prot_pool --> prot_P53239 0.10806918460912467 +usage_prot_P53230 usage_prot_P53230 prot_pool --> prot_P53230 0.0 +usage_prot_P53239 usage_prot_P53239 prot_pool --> prot_P53239 0.0 usage_prot_P53241 usage_prot_P53241 prot_pool --> prot_P53241 0.0 usage_prot_P53257 usage_prot_P53257 prot_pool --> prot_P53257 0.0 usage_prot_P53262 usage_prot_P53262 prot_pool --> prot_P53262 0.0 @@ -7711,7 +7711,7 @@ usage_prot_P53283 usage_prot_P53283 prot_pool --> prot_P53283 0.0 usage_prot_P53296 usage_prot_P53296 prot_pool --> prot_P53296 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usage_prot_Q12265 prot_pool --> prot_Q12265 0.0 usage_prot_Q12271 usage_prot_Q12271 prot_pool --> prot_Q12271 0.0 usage_prot_Q12283 usage_prot_Q12283 prot_pool --> prot_Q12283 0.0 -usage_prot_Q12289 usage_prot_Q12289 prot_pool --> prot_Q12289 0.0001903717407630218 +usage_prot_Q12289 usage_prot_Q12289 prot_pool --> prot_Q12289 0.0 usage_prot_Q12305 usage_prot_Q12305 prot_pool --> prot_Q12305 0.0 usage_prot_Q12320 usage_prot_Q12320 prot_pool --> prot_Q12320 0.0 usage_prot_Q12325 usage_prot_Q12325 prot_pool --> prot_Q12325 0.0 usage_prot_Q12333 usage_prot_Q12333 prot_pool --> prot_Q12333 0.0 -usage_prot_Q12349 usage_prot_Q12349 prot_pool --> prot_Q12349 0.39338716705674254 +usage_prot_Q12349 usage_prot_Q12349 prot_pool --> prot_Q12349 0.022123615775801537 usage_prot_Q12358 usage_prot_Q12358 prot_pool --> prot_Q12358 0.0 -usage_prot_Q12359 usage_prot_Q12359 prot_pool --> prot_Q12359 0.39473465283797227 -usage_prot_Q12362 usage_prot_Q12362 prot_pool --> prot_Q12362 0.018809202598948565 +usage_prot_Q12359 usage_prot_Q12359 prot_pool --> prot_Q12359 0.39473465283797254 +usage_prot_Q12362 usage_prot_Q12362 prot_pool --> prot_Q12362 0.018809202598948305 usage_prot_Q12372 usage_prot_Q12372 prot_pool --> prot_Q12372 0.0 usage_prot_Q12375 usage_prot_Q12375 prot_pool --> prot_Q12375 0.026678809377455353 -usage_prot_Q12382 usage_prot_Q12382 prot_pool --> prot_Q12382 2.330945659249261 -usage_prot_Q12412 usage_prot_Q12412 prot_pool --> prot_Q12412 0.016624603136031472 -usage_prot_Q12428 usage_prot_Q12428 prot_pool --> prot_Q12428 0.0 +usage_prot_Q12382 usage_prot_Q12382 prot_pool --> prot_Q12382 0.0 +usage_prot_Q12412 usage_prot_Q12412 prot_pool --> prot_Q12412 0.016624603136031424 +usage_prot_Q12428 usage_prot_Q12428 prot_pool --> prot_Q12428 0.007121478392959262 usage_prot_Q12436 usage_prot_Q12436 prot_pool --> prot_Q12436 0.0 usage_prot_Q12447 usage_prot_Q12447 prot_pool --> prot_Q12447 0.0 -usage_prot_Q12452 usage_prot_Q12452 prot_pool --> prot_Q12452 0.1126031631706396 +usage_prot_Q12452 usage_prot_Q12452 prot_pool --> prot_Q12452 0.11260316317058862 usage_prot_Q12455 usage_prot_Q12455 prot_pool --> prot_Q12455 0.0007216956676223701 usage_prot_Q12458 usage_prot_Q12458 prot_pool --> prot_Q12458 0.0 usage_prot_Q12471 usage_prot_Q12471 prot_pool --> prot_Q12471 0.0 @@ -7998,14 +7998,14 @@ usage_prot_Q12676 usage_prot_Q12676 prot_pool --> prot_Q12676 9.199454193987252e usage_prot_Q12680 usage_prot_Q12680 prot_pool --> prot_Q12680 0.0 usage_prot_Q12691 usage_prot_Q12691 prot_pool --> prot_Q12691 0.0 usage_prot_Q12746 usage_prot_Q12746 prot_pool --> prot_Q12746 0.0 -usage_prot_Q3E731 usage_prot_Q3E731 prot_pool --> prot_Q3E731 0.033663626790584274 +usage_prot_Q3E731 usage_prot_Q3E731 prot_pool --> prot_Q3E731 0.0 usage_prot_Q3E790 usage_prot_Q3E790 prot_pool --> prot_Q3E790 0.0 usage_prot_Q3E7B6 usage_prot_Q3E7B6 prot_pool --> prot_Q3E7B6 0.0 -usage_prot_Q99190 usage_prot_Q99190 prot_pool --> prot_Q99190 0.0129125079199322 -usage_prot_Q99258 usage_prot_Q99258 prot_pool --> prot_Q99258 0.0005698989734288502 +usage_prot_Q99190 usage_prot_Q99190 prot_pool --> prot_Q99190 0.012839987895754395 +usage_prot_Q99258 usage_prot_Q99258 prot_pool --> prot_Q99258 0.0005698989734288424 usage_prot_Q99271 usage_prot_Q99271 prot_pool --> prot_Q99271 0.0 usage_prot_Q99297 usage_prot_Q99297 prot_pool --> prot_Q99297 0.012854386194880702 usage_prot_Q99312 usage_prot_Q99312 prot_pool --> prot_Q99312 0.0 usage_prot_Q99321 usage_prot_Q99321 prot_pool --> prot_Q99321 0.0 -prot_pool_exchange prot_pool_exchange --> prot_pool 74.32151659601705 -usage_prot_standard usage_prot_standard prot_pool --> prot_standard 0.2725901095134601 +prot_pool_exchange prot_pool_exchange --> prot_pool 53.110960187868436 +usage_prot_standard usage_prot_standard prot_pool --> prot_standard 0.09768188790085316 diff --git a/results/modelSimulation/allFluxes_CN38.tsv b/results/modelSimulation/allFluxes_CN38.tsv index 4a6cc70..162cf35 100644 --- a/results/modelSimulation/allFluxes_CN38.tsv +++ b/results/modelSimulation/allFluxes_CN38.tsv @@ -1,14 +1,14 @@ rxnID rxnName equation flux r_0001_EXP_1 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 3.143317927979973 prot_P32891 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 -r_0001_EXP_2 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 3.143317927979973 prot_P32891 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 +r_0001_EXP_2 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 3.143317927979973 prot_P32891 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.018053681967483835 r_0001_EXP_3 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 2.658626997881764 prot_P39976 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 -r_0001_EXP_4 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 2.658626997881764 prot_P39976 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 +r_0001_EXP_4 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 2.658626997881764 prot_P39976 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.020114633140970395 r_0002_EXP_1 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 2.853264009243212 prot_P46681 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 -r_0002_EXP_2 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 2.853264009243212 prot_P46681 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 +r_0002_EXP_2 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 2.853264009243212 prot_P46681 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.008363940636118547 r_0003 (R,R)-butanediol dehydrogenase 0.11954621771429885 prot_P39714 + (R,R)-2,3-butanediol + NAD --> (R)-acetoin + H+ + NADH 0.0 r_0003_REV (R,R)-butanediol dehydrogenase (reversible) 0.0770037037037037 prot_P39714 + (R)-acetoin + H+ + NADH --> (R,R)-2,3-butanediol + NAD 0.0 r_0004_EXP_1 (S)-lactate:ferricytochrome-c 2-oxidoreductase 0.009357825567502987 prot_P00045 + 0.04893891875746714 prot_P00175 + (S)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 -r_0004_EXP_2 (S)-lactate:ferricytochrome-c 2-oxidoreductase 0.00909647550776583 prot_P00044 + 0.04893891875746714 prot_P00175 + (S)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.02574053929360006 +r_0004_EXP_2 (S)-lactate:ferricytochrome-c 2-oxidoreductase 0.00909647550776583 prot_P00044 + 0.04893891875746714 prot_P00175 + (S)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.025740539283085017 r_0005_EXP_1 1,3-beta-glucan synthase 1.236971332463594 prot_P06780 + 11.479117473701436 prot_P38631 + UDP-D-glucose --> (1->3)-beta-D-glucan + H+ + UDP 0.0 r_0005_EXP_2 1,3-beta-glucan synthase 1.236971332463594 prot_P06780 + 11.593400545580307 prot_P40989 + UDP-D-glucose --> (1->3)-beta-D-glucan + H+ + UDP 0.0 r_0005_EXP_3 1,3-beta-glucan synthase 1.236971332463594 prot_P06780 + 11.085457972250513 prot_Q04952 + UDP-D-glucose --> (1->3)-beta-D-glucan + H+ + UDP 0.07391400000000001 @@ -21,14 +21,14 @@ r_0014 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase 188. r_0015 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH) 0.5311659867712155 prot_P33312 + 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + H+ + NADPH --> 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + NADP(+) 9.999999710998968e-05 r_0016_EXP_1 2-aceto-2-hydroxybutanoate synthase 0.08099546044098574 prot_P07342 + 0.03673476005188067 prot_P25605 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.0 r_0016_EXP_2 2-aceto-2-hydroxybutanoate synthase 0.04049773022049287 prot_P07342 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.0265490320174191 -r_0017 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 63.477512816721614 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + ATP --> (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + AMP + H+ 6.3400002545677125e-06 +r_0017 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 63.477512816721614 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + ATP --> (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + AMP + H+ 6.340000254623224e-06 r_0018_EXP_1 2-aminoadipate transaminase 0.7210471896303212 prot_P10356 + 2-oxoadipic acid + L-glutamate --> 2-oxoglutarate + L-2-aminoadipate 0.0 r_0018_EXP_2 2-aminoadipate transaminase 1.219140625 prot_P53090 + 2-oxoadipic acid + L-glutamate --> 2-oxoglutarate + L-2-aminoadipate 0.0 r_0018_EXP_3 2-aminoadipate transaminase 0.009033549783549784 prot_P47039 + 2-oxoadipic acid + L-glutamate --> 2-oxoglutarate + L-2-aminoadipate 0.032939964005654 r_0018_REV_EXP_1 2-aminoadipate transaminase (reversible) 0.7210471896303212 prot_P10356 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 r_0018_REV_EXP_2 2-aminoadipate transaminase (reversible) 0.8480978260869565 prot_P53090 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 r_0018_REV_EXP_3 2-aminoadipate transaminase (reversible) 1.8137766188613647 prot_P47039 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 -r_0019 2-dehydropantoate 2-reductase 0.4757888888888889 prot_P38787 + 2-dehydropantoate + H+ + NADPH --> (R)-pantoate + NADP(+) 1.900000061120133e-05 +r_0019 2-dehydropantoate 2-reductase 0.4757888888888889 prot_P38787 + 2-dehydropantoate + H+ + NADPH --> (R)-pantoate + NADP(+) 1.9000000611330134e-05 r_0020_EXP_1 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09351092896174863 prot_P14843 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 r_0020_EXP_2 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.03127094379016974 r_0021 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase 0.2834173315594083 prot_O13525 + 0.266570923780901 prot_P27680 + 0.191209663200305 prot_P41735 + 0.2544937516539746 prot_P49017 + 0.39274288726487816 prot_P53318 + 0.21981040253855474 prot_Q05779 + 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine --> 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + S-adenosyl-L-homocysteine 0.0 @@ -36,8 +36,8 @@ r_0022 2-hexaprenyl-6-methoxyphenol monooxygenase 0.5305538973582232 prot_O13525 r_0023 2-isopropylmalate hydratase 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> 2-isopropylmalate 0.0 r_0023_REV 2-isopropylmalate hydratase (reversible) 0.8071027799745517 prot_P07264 + 2-isopropylmalate --> 2-isopropylmaleic acid + H2O 0.0362523293945085 r_0024_EXP_1 2-isopropylmalate synthase 1.3779912980420594 prot_P06208 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.0 -r_0024_EXP_2 2-isopropylmalate synthase 1.353637901861252 prot_Q12166 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.0041453650674776465 -r_0025 2-isopropylmalate synthase 1.3779912980420594 prot_P06208 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.032106964327030856 +r_0024_EXP_2 2-isopropylmalate synthase 1.353637901861252 prot_Q12166 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.0041453650681246845 +r_0025 2-isopropylmalate synthase 1.3779912980420594 prot_P06208 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.03210696432638382 r_0026_EXP_1 2-keto-4-methylthiobutyrate transamination 0.011265116279069768 prot_P38891 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 r_0026_EXP_2 2-keto-4-methylthiobutyrate transamination 0.010755813953488373 prot_P47176 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0013291366958389087 r_0026_EXP_3 2-keto-4-methylthiobutyrate transamination 1.219140625 prot_P53090 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 @@ -47,7 +47,7 @@ r_0027_REV 2-methylcitrate dehydratase (reversible) 8.350111111111111 prot_P4936 r_0028 2-methylcitrate synthase 0.10578556263269638 prot_P43635 + H2O + oxaloacetate + propionyl-CoA --> 2-methylcitrate + coenzyme A + H+ 0.0 r_0029 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.0362523293945085 r_0030 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.0 -r_0032 3',5'-bisphosphate nucleotidase 0.9886111111111111 prot_P32179 + adenosine 3',5'-bismonophosphate + H2O --> AMP + phosphate 0.023173551175571926 +r_0032 3',5'-bisphosphate nucleotidase 0.9886111111111111 prot_P32179 + adenosine 3',5'-bismonophosphate + H2O --> AMP + phosphate 0.023173551175652 r_0033_EXP_1 3',5'-cyclic-nucleotide phosphodiesterase 0.5557671957671958 prot_P22434 + 3',5'-cyclic AMP + H2O --> AMP + H+ 0.0 r_0033_EXP_2 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic AMP + H2O --> AMP + H+ 0.0 r_0034 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic dAMP + H2O --> dAMP + H+ 0.0 @@ -55,17 +55,17 @@ r_0035 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + r_0036 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic GMP + H2O --> GMP + H+ 0.0 r_0037 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic CMP + H2O --> CMP + H+ 0.0 r_0038 3,4-dihydroxy-2-butanone-4-phosphate synthase 2.8494949494949493 prot_Q99258 + D-ribulose 5-phosphate --> 2-hydroxy-3-oxobutyl phosphate + formate + H+ 0.00019999999421997937 -r_0039 3-dehydroquinate dehydratase 0.1565905017921147 prot_P08566 + 3-dehydroquinate --> 3-dehydroshikimate + H2O 0.04370445988538707 -r_0040 3-dehydroquinate synthase 0.1565905017921147 prot_P08566 + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 3-dehydroquinate + phosphate 0.04370445988538707 +r_0039 3-dehydroquinate dehydratase 0.1565905017921147 prot_P08566 + 3-dehydroquinate --> 3-dehydroshikimate + H2O 0.033452483324956706 +r_0040 3-dehydroquinate synthase 0.1565905017921147 prot_P08566 + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 3-dehydroquinate + phosphate 0.033452483324956706 r_0041 3-dehydrosphinganine reductase 9.338785046728972 prot_P38342 + 3-ketosphinganine + H+ + NADPH --> NADP(+) + sphinganine 0.0 -r_0042_EXP_1 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.012433516095217333 +r_0042_EXP_1 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.002181539534786968 r_0042_EXP_2 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09351092896174863 prot_P14843 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 r_0043_EXP_1 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase 0.2467406921478821 prot_Q12184 + 3-hexaprenyl-4-hydroxybenzoic acid + 0.5 oxygen --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 r_0043_EXP_2 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase 0.30872310057092667 prot_P48360 + 3-hexaprenyl-4-hydroxybenzoic acid + 0.5 oxygen --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 r_0044 3-hexaprenyl-4-hydroxy-5-methoxybenzoate decarboxylase 1.6143115942028985 prot_P33751 + 3.391545893719807 prot_Q03034 + 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid + H+ --> 2-hexaprenyl-6-methoxyphenol + carbon dioxide 0.0 -r_0045 3-hydroxy-L-kynurenine hydrolase 4.0501587301587305 prot_Q05979 + 3-hydroxy-L-kynurenine + H2O --> 3-hydroxyanthranilate + H+ + L-alanine 0.000606999997398135 -r_0057 3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxytetradecanoyl-CoA + NAD --> 3-oxotetradecanoyl-CoA + H+ + NADH 0.002857383788379246 -r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.22483333333333333 prot_P47096 + 3-hydroxyanthranilate + oxygen --> 2-amino-3-carboxymuconate-6-semialdehyde 0.000606999997398135 +r_0045 3-hydroxy-L-kynurenine hydrolase 4.0501587301587305 prot_Q05979 + 3-hydroxy-L-kynurenine + H2O --> 3-hydroxyanthranilate + H+ + L-alanine 0.0006069999973967727 +r_0057 3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxytetradecanoyl-CoA + NAD --> 3-oxotetradecanoyl-CoA + H+ + NADH 0.0029317468748953617 +r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.22483333333333333 prot_P47096 + 3-hydroxyanthranilate + oxygen --> 2-amino-3-carboxymuconate-6-semialdehyde 0.0006069999973967727 r_0059 3-isopropylmalate 3-methyltransferase 195.1806339044363 prot_P32643 + (2R,3S)-3-isopropylmalate + S-adenosyl-L-methionine --> 3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoate + S-adenosyl-L-homocysteine 0.0 r_0060 3-isopropylmalate dehydratase 0.6097968324816225 prot_P07264 + (2R,3S)-3-isopropylmalate --> 2-isopropylmaleic acid + H2O 0.0 r_0060_REV 3-isopropylmalate dehydratase (reversible) 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> (2R,3S)-3-isopropylmalate 0.0362523293945085 @@ -73,14 +73,14 @@ r_0061 3-isopropylmalate dehydrogenase 0.06638207225630538 prot_P04173 + (2R,3S) r_0062_EXP_1 3-methyl-2-oxobutanoate decarboxylase 0.27589605734767025 prot_P26263 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 r_0062_EXP_2 3-methyl-2-oxobutanoate decarboxylase 0.11780651340996169 prot_P06169 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 r_0062_EXP_3 3-methyl-2-oxobutanoate decarboxylase 0.27738351254480287 prot_P16467 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 -r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.226834113807293 prot_P38122 + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O --> 2-dehydropantoate + THF 1.900000061120133e-05 +r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.226834113807293 prot_P38122 + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O --> 2-dehydropantoate + THF 1.9000000611330134e-05 r_0064_EXP_1 3-methyl-2-oxopentanoate decarboxylase 0.13096934865900384 prot_Q07471 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_2 3-methyl-2-oxopentanoate decarboxylase 0.27589605734767025 prot_P26263 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_3 3-methyl-2-oxopentanoate decarboxylase 0.11780651340996169 prot_P06169 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_4 3-methyl-2-oxopentanoate decarboxylase 0.27738351254480287 prot_P16467 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 -r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 1.4447337962962963 prot_P08566 + 3-phosphoshikimic acid + phosphoenolpyruvate --> 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid + phosphate 0.04370445988538707 -r_0066 4-amino-4-deoxychorismate synthase 1446.797385620915 prot_P37254 + chorismate + L-glutamine --> 4-amino-4-deoxychorismate + L-glutamate 6.3400002545677125e-06 -r_0067 4-aminobenzoate synthase 6.233918128654971 prot_Q03266 + 4-amino-4-deoxychorismate --> 4-aminobenzoate + H+ + pyruvate 6.3400002545677125e-06 +r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 1.4447337962962963 prot_P08566 + 3-phosphoshikimic acid + phosphoenolpyruvate --> 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid + phosphate 0.033452483324956706 +r_0066 4-amino-4-deoxychorismate synthase 1446.797385620915 prot_P37254 + chorismate + L-glutamine --> 4-amino-4-deoxychorismate + L-glutamate 6.340000254623224e-06 +r_0067 4-aminobenzoate synthase 6.233918128654971 prot_Q03266 + 4-amino-4-deoxychorismate --> 4-aminobenzoate + H+ + pyruvate 6.340000254623224e-06 r_0068 4-aminobutyrate transaminase 43.25653594771242 prot_P17649 + 2-oxoglutarate + gamma-aminobutyrate --> L-glutamate + succinic semialdehyde 0.0 r_0069 4-hydroxy-L-threonine synthase 0.003912990196078431 prot_P16120 + 4-(phosphonooxy)-L-threonine + H2O --> 4-hydroxy-L-threonine + phosphate 0.0 r_0070 4-hydroxybenzoate formation 0.6162073031087573 prot_standard + 4-hydroxybenzoyl-CoA + H2O --> 4-hydroxybenzoate + coenzyme A + H+ 0.0 @@ -94,8 +94,8 @@ r_0076_EXP_2 5'-nucleotidase (CMP) 51.769157967243395 prot_P53078 + CMP + H2O -- r_0077 5'-nucleotidase (IMP) 1.056172839506173 prot_Q99312 + H2O + IMP --> inosine + phosphate 0.0 r_0078_EXP_1 5'-nucleotidase (UMP) 0.029597457627118642 prot_P40025 + H2O + UMP --> phosphate + uridine 0.0 r_0078_EXP_2 5'-nucleotidase (UMP) 201.12835425109543 prot_P53078 + H2O + UMP --> phosphate + uridine 0.0 -r_0079 5'-phosphoribosylformyl glycinamidine synthetase 112.56379587281619 prot_P38972 + 5'-phosphoribosyl-N-formylglycineamide + ATP + H2O + L-glutamine --> 5'-phosphoribosyl-N-formylglycineamidine + ADP + H+ + L-glutamate + phosphate 0.010240426385259176 -r_0080_EXP_1 5,10-methylenetetrahydrofolate reductase (NADPH) 0.12837152777777777 prot_P46151 + 0.11902777777777777 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.02225559248068932 +r_0079 5'-phosphoribosylformyl glycinamidine synthetase 112.56379587281619 prot_P38972 + 5'-phosphoribosyl-N-formylglycineamide + ATP + H2O + L-glutamine --> 5'-phosphoribosyl-N-formylglycineamidine + ADP + H+ + L-glutamate + phosphate 0.01024042638550752 +r_0080_EXP_1 5,10-methylenetetrahydrofolate reductase (NADPH) 0.12837152777777777 prot_P46151 + 0.11902777777777777 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.022255592479884387 r_0080_EXP_2 5,10-methylenetetrahydrofolate reductase (NADPH) 0.3705144833549503 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.0 r_0081 5-aminolevulinate synthase 0.08588252314814815 prot_P09950 + H+ + L-glycine + succinyl-CoA --> 5-aminolevulinate + carbon dioxide + coenzyme A 0.0 r_0082 5-diphosphoinositol-1,2,3,4,6-pentakisphosphate diphosphohydrolase 2396.8888888888887 prot_Q99321 + 5-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 @@ -112,7 +112,7 @@ r_0089_REV 5PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 (reversible) 0.94850146198 r_0090_EXP_1 6-phosphofructo-2-kinase 0.4896069182389937 prot_P40433 + ATP + D-fructose 6-phosphate --> ADP + beta-D-fructose 2,6-bisphosphate + H+ 0.0 r_0090_EXP_2 6-phosphofructo-2-kinase 0.23751572327044027 prot_Q12471 + ATP + D-fructose 6-phosphate --> ADP + beta-D-fructose 2,6-bisphosphate + H+ 0.0 r_0091_EXP_1 6-phosphogluconolactonase 0.8951362104267674 prot_P53315 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.0 -r_0091_EXP_2 6-phosphogluconolactonase 0.87424298616765 prot_P38858 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 6.34934813059651e-13 +r_0091_EXP_2 6-phosphogluconolactonase 0.87424298616765 prot_P38858 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.0 r_0092_EXP_1 6PP-IP5 depyrophosphorylation to IP6 0.9485014619883041 prot_Q06685 + 6-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0092_EXP_2 6PP-IP5 depyrophosphorylation to IP6 2396.8888888888887 prot_Q99321 + 6-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0093 6PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 1106.9444444444443 prot_Q12494 + 6-diphospho-1D-myo-inositol pentakisphosphate + ATP + H+ --> 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + ADP 0.0 @@ -120,26 +120,26 @@ r_0094 8-amino-7-oxononanoate synthase 1.1329040404040405 prot_standard + H+ + L r_0095_EXP_1 acetaldehyde condensation 0.27589605734767025 prot_P26263 + 2.0 acetaldehyde --> (R)-acetoin 0.0 r_0095_EXP_2 acetaldehyde condensation 0.11780651340996169 prot_P06169 + 2.0 acetaldehyde --> (R)-acetoin 0.0 r_0095_EXP_3 acetaldehyde condensation 0.27738351254480287 prot_P16467 + 2.0 acetaldehyde --> (R)-acetoin 0.0 -r_0096 acetohydroxy acid isomeroreductase 0.6734669095324833 prot_P06168 + 2-acetyllactic acid + H+ + NADPH --> (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) 0.06773178437260571 +r_0096 acetohydroxy acid isomeroreductase 0.6734669095324833 prot_P06168 + 2-acetyllactic acid + H+ + NADPH --> (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) 0.06773178437260584 r_0097_EXP_1 acetolactate synthase 0.16199092088197148 prot_P07342 + 0.07346952010376134 prot_P25605 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.0 -r_0097_EXP_2 acetolactate synthase 0.08099546044098574 prot_P07342 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.06773178437260571 +r_0097_EXP_2 acetolactate synthase 0.08099546044098574 prot_P07342 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.06773178437260584 r_0099 acetyl-CoA ACP transacylase 0.2585296857817232 prot_P32463 + acetyl-CoA + ACP1 --> acetyl-ACP + coenzyme A 0.0 r_0099_REV acetyl-CoA ACP transacylase (reversible) 0.29722261474049355 prot_P32463 + acetyl-ACP + coenzyme A --> acetyl-CoA + ACP1 0.0 -r_0100 acetyl-CoA C-acyltransferase (palmitoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxooctadecanoyl-CoA + coenzyme A --> acetyl-CoA + palmitoyl-CoA 0.003112777446067193 -r_0101 acetyl-CoA C-acyltransferase (tetracosanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxohexacosanoyl-CoA + coenzyme A --> acetyl-CoA + tetracosanoyl-CoA 0.0003717106244277723 -r_0102 acetyl-CoA C-acyltransferase (myristoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxopalmitoyl-CoA + coenzyme A --> acetyl-CoA + myristoyl-CoA 0.003112777444882465 +r_0100 acetyl-CoA C-acyltransferase (palmitoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxooctadecanoyl-CoA + coenzyme A --> acetyl-CoA + palmitoyl-CoA 0.003187140532803099 +r_0101 acetyl-CoA C-acyltransferase (tetracosanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxohexacosanoyl-CoA + coenzyme A --> acetyl-CoA + tetracosanoyl-CoA 0.0003717106243194283 +r_0102 acetyl-CoA C-acyltransferase (myristoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxopalmitoyl-CoA + coenzyme A --> acetyl-CoA + myristoyl-CoA 0.003187140538307717 r_0103 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.0 -r_0103_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA 0.010251976559931349 -r_0104 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.022347724063098005 +r_0103_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA -4.977216555568376e-13 +r_0104 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.022347724064798527 r_0104_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA 0.0 -r_0105 acetyl-CoA C-acyltransferase (lauroyl-CoA) 0.839527027027027 prot_P27796 + 3-oxotetradecanoyl-CoA + coenzyme A --> acetyl-CoA + lauroyl-CoA 0.002857383788379246 -r_0106 acetyl-CoA C-acyltransferase (octanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxodecanoyl-CoA + coenzyme A --> acetyl-CoA + octanoyl-CoA 0.00028144707955366557 -r_0107 acetyl-CoA C-acyltransferase (decanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxolauroyl-CoA + coenzyme A --> acetyl-CoA + decanoyl-CoA 0.002415660218418773 +r_0105 acetyl-CoA C-acyltransferase (lauroyl-CoA) 0.839527027027027 prot_P27796 + 3-oxotetradecanoyl-CoA + coenzyme A --> acetyl-CoA + lauroyl-CoA 0.0029317468748953617 +r_0106 acetyl-CoA C-acyltransferase (octanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxodecanoyl-CoA + coenzyme A --> acetyl-CoA + octanoyl-CoA 0.0002365045025291035 +r_0107 acetyl-CoA C-acyltransferase (decanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxolauroyl-CoA + coenzyme A --> acetyl-CoA + decanoyl-CoA 0.002490023304934889 r_0108 acetyl-Coa carboxylase 8.46937908496732 prot_P32874 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.0 r_0109 acetyl-CoA carboxylase, reaction 2.608229839040149 prot_P48445 + 8.55097579839999 prot_Q00955 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.14301503011146485 r_0111 acetyl-CoA hydrolase 2.24640342822161 prot_P32316 + acetyl-CoA + H2O --> acetate + coenzyme A + H+ 0.0 r_0112_EXP_1 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 -r_0112_EXP_2 acetyl-CoA synthetase 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.15868889711923395 +r_0112_EXP_2 acetyl-CoA synthetase 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.1791822269417091 r_0113 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.07048353427211616 r_0114 acetyl-CoA synthetase nuclear 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 r_0115 acetylglutamate kinase 3.4224025974025976 prot_Q01217 + ATP + N-acetyl-L-glutamate --> ADP + N-acetyl-L-gamma-glutamyl phosphate 0.031073733655750127 @@ -151,12 +151,12 @@ r_0117 aconitase 356.0740740740741 prot_Q12428 + 2-methylcitrate --> (2S,3R)-3-h r_0117_REV aconitase (reversible) 0.0015170737865303288 prot_Q12428 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> 2-methylcitrate 0.0 r_0118 acteylornithine transaminase 5.836456209941037 prot_P18544 + 2-acetamido-5-oxopentanoate + L-glutamate --> 2-oxoglutarate + N(2)-acetyl-L-ornithine 0.031073733655750127 r_0119 acyl carrier protein synthase 1.9814484126984127 prot_Q12036 + coenzyme A + H2O --> adenosine 3',5'-bismonophosphate + 2.0 H+ + pantetheine 4'-phosphate 0.011129385395862026 -r_0120 acyl-CoA oxidase (decanoyl-CoA) 15.258169934640524 prot_P13711 + decanoyl-CoA + oxygen --> hydrogen peroxide + trans-dec-2-enoyl-CoA 0.0 -r_0121 acyl-CoA oxidase (dodecanoyl-CoA) 2.7176949941792783 prot_P13711 + lauroyl-CoA + oxygen --> hydrogen peroxide + trans-dodec-2-enoyl-CoA 0.002415660218418773 -r_0122 acyl-CoA oxidase (hexacosanoyl-CoA) 2.7176949941792783 prot_P13711 + hexacosanoyl-CoA + oxygen --> hydrogen peroxide + trans-hexacos-2-enoyl-CoA 0.0003717106244277723 -r_0123 acyl-CoA oxidase (hexadecanoyl-CoA) 0.2992948717948718 prot_P13711 + oxygen + palmitoyl-CoA --> hexadec-2-enoyl-CoA + hydrogen peroxide 0.003112777444882465 -r_0124 acyl-CoA oxidase (octadecanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + stearoyl-CoA --> hydrogen peroxide + trans-octadec-2-enoyl-CoA 0.003112777446067193 -r_0125 acyl-CoA oxidase (tetradecanoyl-CoA) 2.7176949941792783 prot_P13711 + myristoyl-CoA + oxygen --> hydrogen peroxide + trans-tetradec-2-enoyl-CoA 0.002857383788379246 +r_0120 acyl-CoA oxidase (decanoyl-CoA) 15.258169934640524 prot_P13711 + decanoyl-CoA + oxygen --> hydrogen peroxide + trans-dec-2-enoyl-CoA 4.004380852183325e-05 +r_0121 acyl-CoA oxidase (dodecanoyl-CoA) 2.7176949941792783 prot_P13711 + lauroyl-CoA + oxygen --> hydrogen peroxide + trans-dodec-2-enoyl-CoA 0.002490023304934889 +r_0122 acyl-CoA oxidase (hexacosanoyl-CoA) 2.7176949941792783 prot_P13711 + hexacosanoyl-CoA + oxygen --> hydrogen peroxide + trans-hexacos-2-enoyl-CoA 0.0003717106243194283 +r_0123 acyl-CoA oxidase (hexadecanoyl-CoA) 0.2992948717948718 prot_P13711 + oxygen + palmitoyl-CoA --> hexadec-2-enoyl-CoA + hydrogen peroxide 0.003187140538307717 +r_0124 acyl-CoA oxidase (octadecanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + stearoyl-CoA --> hydrogen peroxide + trans-octadec-2-enoyl-CoA 0.003187140532803099 +r_0125 acyl-CoA oxidase (tetradecanoyl-CoA) 2.7176949941792783 prot_P13711 + myristoyl-CoA + oxygen --> hydrogen peroxide + trans-tetradec-2-enoyl-CoA 0.0029317468748953617 r_0126 acyl-CoA:sterol acyltransferase (oleoyl-CoA:episterol), ER membrane 65.94767724903261 prot_P25628 + oleoyl-CoA + episterol --> coenzyme A + episteryl oleate 0.0 r_0126_REV acyl-CoA:sterol acyltransferase (oleoyl-CoA:episterol), ER membrane (reversible) 3.9740642147807406 prot_P25628 + coenzyme A + episteryl oleate --> oleoyl-CoA + episterol 0.0 r_0127_EXP_1 acyl-CoA:sterol acyltransferase (oleoyl-CoA:ergosterol), ER membrane 64.38822905167784 prot_P25628 + oleoyl-CoA + ergosterol --> coenzyme A + ergosteryl oleate 0.0 @@ -184,23 +184,23 @@ r_0138 adenine deaminase 2.0017676767676766 prot_P53909 + adenine + H+ + H2O --> r_0139_EXP_1 adenine phosphoribosyltransferase 0.5950339406931047 prot_P36973 + adenine + PRPP --> AMP + diphosphate 0.0 r_0139_EXP_2 adenine phosphoribosyltransferase 0.6129272359175896 prot_P49435 + adenine + PRPP --> AMP + diphosphate 0.0 r_0140 adenosine deaminase 2.0017676767676766 prot_P53909 + adenosine + H+ + H2O --> ammonium + inosine 0.0 -r_0142 adenosine kinase 0.3962091503267974 prot_P47143 + adenosine + ATP --> ADP + AMP + H+ 0.015434982529254616 +r_0142 adenosine kinase 0.3962091503267974 prot_P47143 + adenosine + ATP --> ADP + AMP + H+ 0.01543498252844911 r_0143 adenosine monophosphate deaminase 21.282895302745313 prot_P15274 + AMP + H+ + H2O --> ammonium + IMP 0.0 -r_0144 adenosylhomocysteinase 0.023732367149758453 prot_P39954 + H2O + S-adenosyl-L-homocysteine --> adenosine + L-homocysteine 0.014105845833415707 +r_0144 adenosylhomocysteinase 0.023732367149758453 prot_P39954 + H2O + S-adenosyl-L-homocysteine --> adenosine + L-homocysteine 0.014105845832610202 r_0145 adenosylmethionine decarboxylase 7.554248366013072 prot_P21182 + H+ + S-adenosyl-L-methionine --> carbon dioxide + S-adenosylmethioninamine 0.0013291366958389087 r_0146 adenosylmethionine-8-amino-7-oxononanoate transaminase 14.919166666666667 prot_P50277 + 8-amino-7-oxononanoate + S-adenosyl-L-methionine --> 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate 0.0 r_0146_REV adenosylmethionine-8-amino-7-oxononanoate transaminase (reversible) 14.919166666666667 prot_P50277 + 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate --> 8-amino-7-oxononanoate + S-adenosyl-L-methionine 0.0 r_0147 adenylate cyclase 0.013758091787439614 prot_P08678 + ATP --> 3',5'-cyclic AMP + diphosphate 0.0 r_0148_EXP_1 adenylate kinase 0.007176741835638936 prot_Q12055 + AMP + ATP --> 2.0 ADP 0.18949508429581247 -r_0148_EXP_2 adenylate kinase 0.007660602615122228 prot_P07170 + AMP + ATP --> 2.0 ADP 0.5585783735484514 +r_0148_EXP_2 adenylate kinase 0.007660602615122228 prot_P07170 + AMP + ATP --> 2.0 ADP 0.5688197284199163 r_0149 adenylate kinase 10.450950897581233 prot_P26364 + AMP + ATP --> 2.0 ADP 0.0 -r_0150 adenylate kinase (GTP) 10.495327582667667 prot_P26364 + AMP + GTP --> ADP + GDP 0.07048987427237073 +r_0150 adenylate kinase (GTP) 10.495327582667667 prot_P26364 + AMP + GTP --> ADP + GDP 0.07048987427237079 r_0150_REV adenylate kinase (GTP) (reversible) 2.5045140533551153 prot_P26364 + ADP + GDP --> AMP + GTP 0.0 -r_0151 adenylosuccinate lyase (AICAR) 0.04493076162215628 prot_Q05911 + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole --> AICAR + fumarate 0.010240306385254931 -r_0152 adenylosuccinate lyase 0.04493076162215628 prot_Q05911 + adenylo-succinate --> AMP + fumarate 0.013797191947412739 +r_0151 adenylosuccinate lyase (AICAR) 0.04493076162215628 prot_Q05911 + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole --> AICAR + fumarate 0.010240306385503275 +r_0152 adenylosuccinate lyase 0.04493076162215628 prot_Q05911 + adenylo-succinate --> AMP + fumarate 0.013797191947661028 r_0152_REV adenylosuccinate lyase (reversible) 5.221264367816092 prot_Q05911 + AMP + fumarate --> adenylo-succinate 0.0 -r_0153 adenylosuccinate synthase 2.4383333333333335 prot_P80210 + GTP + IMP + L-aspartate --> adenylo-succinate + GDP + 2.0 H+ + phosphate 0.013797191947412739 -r_0154 adenylyl-sulfate kinase 1.4558080808080807 prot_Q02196 + 5'-adenylyl sulfate + ATP --> 3'-phospho-5'-adenylyl sulfate + ADP + H+ 0.012044165779709898 +r_0153 adenylosuccinate synthase 2.4383333333333335 prot_P80210 + GTP + IMP + L-aspartate --> adenylo-succinate + GDP + 2.0 H+ + phosphate 0.013797191947661028 +r_0154 adenylyl-sulfate kinase 1.4558080808080807 prot_Q02196 + 5'-adenylyl sulfate + ATP --> 3'-phospho-5'-adenylyl sulfate + ADP + H+ 0.012044165779789976 r_0155 ADP-ribose 2,3-cyclic phosphodiesterase 0.00789952718676123 prot_P53314 + 2',3'-cyclic AMP + H2O --> adenosine 2'-phosphate + H+ 0.0 r_0156 alanine glyoxylate aminotransferase 0.08886132315521629 prot_P43567 + glyoxylate + L-alanine --> L-glycine + pyruvate 0.0 r_0157 alanyl-tRNA synthetase 0.25476620370370373 prot_P40825 + ATP + L-alanine + tRNA(Ala) --> Ala-tRNA(Ala) + AMP + diphosphate 0.0347736630768556 @@ -236,10 +236,10 @@ r_0171_EXP_1 aldehyde dehydrogenase (2-phenylethanol, NADP) 1.6815384615384616 p r_0171_EXP_2 aldehyde dehydrogenase (2-phenylethanol, NADP) 0.012227777777777778 prot_Q04894 + H+ + NADPH + phenylacetaldehyde --> 2-phenylethanol + NADP(+) 0.0 r_0172_EXP_1 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.483596214511041 prot_P47771 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 0.0 r_0172_EXP_2 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.06410300925925926 prot_P54114 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 0.0013291366958389087 -r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.27726867610406014 -r_0174 aldehyde dehydrogenase (acetylaldehyde, NAD) 1.6231765567058962 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 1.464364125891696 -r_0175_EXP_1 aldehyde dehydrogenase (acetylaldehyde, NADP) 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.004776839999999999 -r_0175_EXP_2 aldehyde dehydrogenase (acetylaldehyde, NADP) 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.12057771004577494 +r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.32669532503386556 +r_0174 aldehyde dehydrogenase (acetylaldehyde, NAD) 1.6231765567058962 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.1367268745307243 +r_0175_EXP_1 aldehyde dehydrogenase (acetylaldehyde, NADP) 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.0 +r_0175_EXP_2 aldehyde dehydrogenase (acetylaldehyde, NADP) 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.12535455004577506 r_0176 aldehyde dehydrogenase (indole-3-acetaldehyde, NAD) 2.9233283159832175 prot_P46367 + H2O + indol-3-ylacetaldehyde + NAD --> 2.0 H+ + indole-3-acetate + NADH 0.0 r_0177 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + H2O + indol-3-ylacetaldehyde + NADP(+) --> 2.0 H+ + indole-3-acetate + NADPH 0.0 r_0178_EXP_1 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 2.027300005914026 prot_P40047 + H2O + indol-3-ylacetaldehyde + NADP(+) --> 2.0 H+ + indole-3-acetate + NADPH 0.0 @@ -265,7 +265,7 @@ r_0186_EXP_2 aldehyde dehydrogenase (tryptophol, NAD) 0.0069274810448778975 prot r_0186_EXP_3 aldehyde dehydrogenase (tryptophol, NAD) 0.011373148148148148 prot_P00330 + H+ + indol-3-ylacetaldehyde + NADH --> NAD + tryptophol 0.0 r_0187_EXP_1 aldehyde dehydrogenase (tryptophol, NAD) 0.012698148148148148 prot_P10127 + H+ + indol-3-ylacetaldehyde + NADH --> NAD + tryptophol 0.0 r_0187_EXP_2 aldehyde dehydrogenase (tryptophol, NAD) 0.006814054134343373 prot_P07246 + H+ + indol-3-ylacetaldehyde + NADH --> NAD + tryptophol 0.0 -r_0188 alkaline phosphatase (dihydroneopterin) 0.6294430181013366 prot_P11491 + 7,8-dihydroneopterin 3'-triphosphate + 3.0 H2O --> 7,8-dihydroneopterin + 2.0 H+ + 3.0 phosphate 6.3400002545677125e-06 +r_0188 alkaline phosphatase (dihydroneopterin) 0.6294430181013366 prot_P11491 + 7,8-dihydroneopterin 3'-triphosphate + 3.0 H2O --> 7,8-dihydroneopterin + 2.0 H+ + 3.0 phosphate 6.340000254623224e-06 r_0189 allantoate amidinohydrolase 0.014338518518518518 prot_P25335 + allantoate + H2O --> urea + ureidoglycolic acid 0.0 r_0189_REV allantoate amidinohydrolase (reversible) 0.014338518518518518 prot_P25335 + urea + ureidoglycolic acid --> allantoate + H2O 0.0 r_0190 allantoinase, reaction 0.033152116402116405 prot_P32375 + allantoin + H2O --> allantoate + H+ 0.0 @@ -294,8 +294,8 @@ r_0199_EXP_1 amidase 0.002363959719142646 prot_P22580 + 4-guanidinobutanamide + r_0199_EXP_2 amidase 0.002263428815277111 prot_Q03557 + 4-guanidinobutanamide + H2O --> 4-guanidinobutanoic acid + ammonium 0.0 r_0200 Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing) 0.062476381011109826 prot_standard + aminoacetone + H2O + oxygen --> ammonium + hydrogen peroxide + methylglyoxal 0.0 r_0201 Aminobutyraldehyde dehydrogenase 6.571504396261395 prot_P46367 + 4-aminobutanal + H2O + NAD --> gamma-aminobutyrate + 2.0 H+ + NADH 0.0 -r_0202 anthranilate phosphoribosyltransferase 2.8570423609142406 prot_P07285 + anthranilate + PRPP --> diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate 0.004508621257676927 -r_0203 anthranilate synthase 0.11426731078904992 prot_P00899 + 0.1076670692431562 prot_P00937 + chorismate + L-glutamine --> anthranilate + H+ + L-glutamate + pyruvate 0.004463981443243956 +r_0202 anthranilate phosphoribosyltransferase 2.8570423609142406 prot_P07285 + anthranilate + PRPP --> diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate 0.004508621257677068 +r_0203 anthranilate synthase 0.11426731078904992 prot_P00899 + 0.1076670692431562 prot_P00937 + chorismate + L-glutamine --> anthranilate + H+ + L-glutamate + pyruvate 0.004463981443242593 r_0204 Ap4A hydrolase 0.16307795442894646 prot_P49775 + H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate --> 2.0 ADP + 2.0 H+ 0.0 r_0204_REV Ap4A hydrolase (reversible) 0.1607002693067822 prot_P49775 + 2.0 ADP + 2.0 H+ --> H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate 0.0 r_0205 arabinose reductase 0.01001051779935275 prot_P38715 + H+ + L-arabinose + NADPH --> L-arabinitol + NADP(+) 0.0 @@ -310,30 +310,30 @@ r_0211_EXP_1 asparagine synthase (glutamine-hydrolysing) 1.9523939064200218 prot r_0211_EXP_2 asparagine synthase (glutamine-hydrolysing) 1.948676097207109 prot_P49089 + ATP + H2O + L-aspartate + L-glutamine --> AMP + diphosphate + H+ + L-asparagine + L-glutamate 0.019146806720785902 r_0212 Asparaginyl-tRNA synthetase 1.710863586358636 prot_P38707 + ATP + L-asparagine + tRNA(Asn) --> AMP + Asn-tRNA(Asn) + diphosphate 0.019146806720785902 r_0213 asparaginyl-tRNA synthetase, miotchondrial 1.5617436743674367 prot_P25345 + ATP + L-asparagine + tRNA(Asn) --> AMP + Asn-tRNA(Asn) + diphosphate 0.0 -r_0214 aspartate carbamoyltransferase 0.1632300826005862 prot_P07259 + carbamoyl phosphate + L-aspartate --> H+ + N-carbamoyl-L-aspartate + phosphate 0.010726833614579979 -r_0215 aspartate kinase 0.0711086637298091 prot_P10869 + ATP + L-aspartate --> 4-phospho-L-aspartate + ADP 0.03579652043784406 +r_0214 aspartate carbamoyltransferase 0.1632300826005862 prot_P07259 + carbamoyl phosphate + L-aspartate --> H+ + N-carbamoyl-L-aspartate + phosphate 0.010726833614579982 +r_0215 aspartate kinase 0.0711086637298091 prot_P10869 + ATP + L-aspartate --> 4-phospho-L-aspartate + ADP 0.03579652043784409 r_0216 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.0 -r_0216_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.1331732742999852 +r_0216_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.1331732743004819 r_0217 aspartate transaminase 0.021473880597014924 prot_Q01802 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.0 r_0218 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.0 r_0218_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.0 -r_0219 aspartate-semialdehyde dehydrogenase 26.415673633916466 prot_P13663 + 4-phospho-L-aspartate + H+ + NADPH --> L-aspartate 4-semialdehyde + NADP(+) + phosphate 0.03579652043784406 +r_0219 aspartate-semialdehyde dehydrogenase 26.415673633916466 prot_P13663 + 4-phospho-L-aspartate + H+ + NADPH --> L-aspartate 4-semialdehyde + NADP(+) + phosphate 0.03579652043784409 r_0220 Aspartyl-tRNA synthetase 0.7351388888888889 prot_P04802 + ATP + L-aspartate + tRNA(Asp) --> AMP + Asp-tRNA(Asp) + diphosphate 0.0240359946744132 r_0221 Aspartyl-tRNA synthetase 0.8733912037037037 prot_P15179 + ATP + L-aspartate + tRNA(Asp) --> AMP + Asp-tRNA(Asp) + diphosphate 0.0 r_0222 ATP adenylyltransferase 0.10660011574074074 prot_P22108 + ADP + ATP + H+ --> P(1),P(4)-bis(5'-adenosyl) tetraphosphate + phosphate 0.0 r_0223 ATP adenylyltransferase 0.10559317129629629 prot_P16550 + ADP + GTP + H+ --> P1-(5'-adenosyl),P4-(5'-guanosyl) tetraphosphate + phosphate 0.0 r_0224 ATP adenylyltransferase 0.10559317129629629 prot_P16550 + GDP + GTP + H+ --> P(1),P(4)-bis(5'-guanosyl) tetraphosphate + phosphate 0.0 r_0225 ATP phosphoribosyltransferase 0.8298868312757202 prot_P00498 + ATP + PRPP --> 5-phosphoribosyl-ATP + diphosphate 0.008356708763266002 -r_0226 ATP synthase 0.5394232482136998 prot_P00830 + 0.09548902616935218 prot_P00854 + 0.019105024583592853 prot_P00856 + 0.08835499603456501 prot_P05626 + 0.5769704298154636 prot_P07251 + 0.07486465662145093 prot_P09457 + 0.022127306899204155 prot_P21306 + 0.06500696272775239 prot_P30902 + 0.11272358287031914 prot_P38077 + 0.25461333861919777 prot_P61829 + 0.0356898398095424 prot_P81449 + 0.021946823156143762 prot_P81450 + 0.024722991276672712 prot_P81451 + 0.03712058366362115 prot_Q06405 + 0.05585151467068882 prot_Q12165 + 0.04240055352878791 prot_Q12233 + 0.04636135130831326 prot_Q12349 + ADP + 3.0 H+ + phosphate --> ATP + 2.0 H+ + H2O 11.674163911653855 +r_0226 ATP synthase 0.028401930104729925 prot_P00830 + 0.005027726661784965 prot_P00854 + 0.0010059254484659976 prot_P00856 + 0.004652102834068531 prot_P05626 + 0.03037887943165331 prot_P07251 + 0.0039418040503784385 prot_P09457 + 0.0011650558740993167 prot_P21306 + 0.0034227727815375154 prot_P30902 + 0.005935167482008843 prot_P38077 + 0.013406004044396558 prot_P61829 + 0.0018791558188794555 prot_P81449 + 0.0011555529713742 prot_P81450 + 0.0013017248932914508 prot_P81451 + 0.0019544879204821996 prot_Q06405 + 0.0029407164432997735 prot_Q12165 + 0.002232491020204252 prot_Q12233 + 0.0024410365400081785 prot_Q12349 + ADP + 3.0 H+ + phosphate --> ATP + 2.0 H+ + H2O 11.767207031755502 r_0226_REV ATP synthase (reversible) 0.3805138888888889 prot_P00830 + 0.06735879629629629 prot_P00854 + 0.013476851851851853 prot_P00856 + 0.06232638888888889 prot_P05626 + 0.407 prot_P07251 + 0.05281018518518518 prot_P09457 + 0.015608796296296296 prot_P21306 + 0.045856481481481484 prot_P30902 + 0.0795162037037037 prot_P38077 + 0.17960648148148148 prot_P61829 + 0.025175925925925925 prot_P81449 + 0.015481481481481481 prot_P81450 + 0.017439814814814814 prot_P81451 + 0.026185185185185186 prot_Q06405 + 0.03939814814814815 prot_Q12165 + 0.029909722222222223 prot_Q12233 + 0.03270370370370371 prot_Q12349 + ATP + 2.0 H+ + H2O --> ADP + 3.0 H+ + phosphate 0.0 r_0227_EXP_1 ATPase, plasma membrane 4.61199074074074 prot_P05030 + 0.20837962962962964 prot_P32903 + 0.22444444444444445 prot_P40975 + ATP + H2O --> ADP + H+ + phosphate 0.0 r_0227_EXP_2 ATPase, plasma membrane 4.730185185185185 prot_P19657 + 0.20837962962962964 prot_P32903 + 0.22444444444444445 prot_P40975 + ATP + H2O --> ADP + H+ + phosphate 0.0 -r_0227_EXP_3 ATPase, plasma membrane 0.023208010335917312 prot_P40009 + ATP + H2O --> ADP + H+ + phosphate 1.1153291299658687 +r_0227_EXP_3 ATPase, plasma membrane 0.023208010335917312 prot_P40009 + ATP + H2O --> ADP + H+ + phosphate 1.0564536134859268 r_0228 beta-1,4 mannosyltransferase 63.94951949233543 prot_P16661 + GDP-alpha-D-mannose + N,N'-diacetylchitobiosyldiphosphodolichol --> beta-D-mannosyldiacetylchitobiosyldiphosphodolichol + GDP + H+ 0.0 r_0229 biotin synthase 0.8370103916866507 prot_P32451 + dethiobiotin + polysulphur --> biotin + 2.0 H+ 0.0 r_0229_REV biotin synthase (reversible) 0.8370103916866507 prot_P32451 + biotin + 2.0 H+ --> dethiobiotin + polysulphur 0.0 r_0230 biotin-[acetyl-CoA-carboxylase] ligase 4.713765432098766e-05 prot_P48445 + ATP + biotin + H+ --> biotinyl-5'-AMP + diphosphate 0.0 -r_0231 C-14 sterol reductase 4.194445624507709 prot_P32462 + 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H+ + NADPH --> 14-demethyllanosterol + NADP(+) 0.003724620677183001 +r_0231 C-14 sterol reductase 4.194445624507709 prot_P32462 + 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H+ + NADPH --> 14-demethyllanosterol + NADP(+) 0.003724620677466421 r_0233 C-22 sterol desaturase (NADP) 100.21895424836602 prot_P54781 + ergosta-5,7,24(28)-trien-3beta-ol + H+ + NADPH + oxygen --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2.0 H2O + NADP(+) 0.00033112378423656285 r_0234 C-3 sterol dehydrogenase 3.093923129380329 prot_P53199 + NADP(+) + zymosterol intermediate 1c --> carbon dioxide + NADPH + zymosterol intermediate 2 0.0037246206773107857 r_0235 C-3 sterol dehydrogenase (4-methylzymosterol) 8.806624430682128 prot_P53199 + 4beta-methylzymosterol-4alpha-carboxylic acid + NAD --> 3-dehydro-4-methylzymosterol + carbon dioxide + NADH 0.0037246206773107857 @@ -347,12 +347,12 @@ r_0242 C-5 sterol desaturase 24.953439493862604 prot_P32353 + episterol + H+ + N r_0243 C-8 sterol isomerase 11.181301444435384 prot_P32352 + fecosterol --> episterol 0.0003311237842365629 r_0244 C-s24 sterol reductase 1.5624148864343401 prot_P25340 + ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + NADPH --> ergosterol + NADP(+) 0.003687743244862164 r_0249 CAAX farnesyltransferase 4.1518225763666585 prot_P22007 + 3.231511956720494 prot_P29703 + 4-hydroxybenzoate + nonaprenyl diphosphate --> diphosphate + nonaprenyl 4-hydroxybenzoate 0.0 -r_0250_EXP_1 carbamoyl-phosphate synthase (glutamine-hydrolysing) 0.01089245390373571 prot_P07259 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.03015645413427438 +r_0250_EXP_1 carbamoyl-phosphate synthase (glutamine-hydrolysing) 0.01089245390373571 prot_P07259 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.030156454134274382 r_0250_EXP_2 carbamoyl-phosphate synthase (glutamine-hydrolysing) 3.661790780141844 prot_P03965 + 1.34048463356974 prot_P07258 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.0 r_0252_EXP_1 carnitine O-acetyltransferase 0.016201655041376033 prot_P80235 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 r_0252_EXP_2 carnitine O-acetyltransferase 0.05053501564945227 prot_P40017 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 -r_0253 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.007202150381957033 -r_0254 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + coenzyme A + O-acetylcarnitine --> (R)-carnitine + acetyl-CoA 0.007202150381957033 +r_0253 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.007019930692418554 +r_0254 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + coenzyme A + O-acetylcarnitine --> (R)-carnitine + acetyl-CoA 0.007019930692418554 r_0255 catalase 6.339124460149195e-06 prot_P06115 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0 r_0256 catalase 5.747447978013349e-06 prot_P15202 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0 r_0259 ceramide-1 hydroxylase (24C) 0.035359375 prot_P38992 + ceramide-1 (C24) + H+ + NADPH + oxygen --> ceramide-2 (C24) + H2O + NADP(+) 0.0 @@ -372,11 +372,11 @@ r_0271_EXP_2 chitin deacetylase 0.01794357473933983 prot_Q06703 + chitin + H2O - r_0272_EXP_1 chitin synthase 80.72709323101475 prot_P29465 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0 r_0272_EXP_2 chitin synthase 13.190119547029806 prot_P14180 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0023610000000000003 r_0272_EXP_3 chitin synthase 188.53265572369114 prot_P08004 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0 -r_0273 choline kinase 7.224074074074074 prot_P20485 + ATP + choline --> ADP + choline phosphate + H+ 0.0036216614344410166 -r_0274 choline phosphate cytididyltransferase 0.4121287954621288 prot_P13259 + choline phosphate + CTP + H+ --> CDP-choline + diphosphate 0.0036216614344410166 -r_0278 chorismate mutase 0.02288935056940597 prot_P32178 + chorismate --> prephenate 0.03923413844188855 -r_0279 chorismate synthase 0.3336437908496732 prot_P28777 + 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid --> chorismate + phosphate 0.04370445988538707 -r_0280 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.0 +r_0273 choline kinase 7.224074074074074 prot_P20485 + ATP + choline --> ADP + choline phosphate + H+ 0.0036216615321250233 +r_0274 choline phosphate cytididyltransferase 0.4121287954621288 prot_P13259 + choline phosphate + CTP + H+ --> CDP-choline + diphosphate 0.0036216615321250233 +r_0278 chorismate mutase 0.02288935056940597 prot_P32178 + chorismate --> prephenate 0.028982161881459488 +r_0279 chorismate synthase 0.3336437908496732 prot_P28777 + 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid --> chorismate + phosphate 0.033452483324956706 +r_0280 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.0631482417411815 r_0280_REV cis-aconitate(3-) to isocitrate (reversible) 0.16582750582750583 prot_P19414 + isocitrate --> cis-aconitate + H2O 0.0 r_0281_EXP_1 cis-prenyltransferase step 01 40.954572225982666 prot_P35196 + farnesyl diphosphate + isopentenyl diphosphate --> diphosphate + geranylgeranyl diphosphate 0.0 r_0281_EXP_2 cis-prenyltransferase step 01 30.078354060470264 prot_Q03175 + farnesyl diphosphate + isopentenyl diphosphate --> diphosphate + geranylgeranyl diphosphate 0.0 @@ -420,28 +420,28 @@ r_0298_EXP_1 cis-prenyltransferase step 18 40.954572225982666 prot_P35196 + icos r_0298_EXP_2 cis-prenyltransferase step 18 30.078354060470264 prot_Q03175 + icosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + henicosaprenyl diphosphate 0.0 r_0299_EXP_1 cis-prenyltransferase step 19 40.954572225982666 prot_P35196 + henicosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + docosaprenyl diphosphate 0.0 r_0299_EXP_2 cis-prenyltransferase step 19 30.078354060470264 prot_Q03175 + henicosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + docosaprenyl diphosphate 0.0 -r_0300_EXP_1 citrate synthase 0.10489895415585436 prot_P00890 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 1.5454656485715652 +r_0300_EXP_1 citrate synthase 0.10489895415585436 prot_P00890 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 1.5488829740907137 r_0300_EXP_2 citrate synthase 0.10578556263269638 prot_P43635 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.0 -r_0301 citrate synthase, peroxisomal 1.275124007936508 prot_P08679 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.008034867649931332 -r_0302 citrate to cis-aconitate(3-) 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.0 +r_0301 citrate synthase, peroxisomal 1.275124007936508 prot_P08679 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.00803486765046755 +r_0302 citrate to cis-aconitate(3-) 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.0631482417411815 r_0302_REV citrate to cis-aconitate(3-) (reversible) 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> citrate 0.0 -r_0303 citrate to cis-aconitate(3-), cytoplasmic 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 1.5535005162214965 +r_0303 citrate to cis-aconitate(3-), cytoplasmic 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 1.4937695999999998 r_0303_REV citrate to cis-aconitate(3-), cytoplasmic (reversible) 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> citrate 0.0 r_0304 coproporphyrinogen oxidase (O2 required) 616.2091503267974 prot_P11353 + coproporphyrinogen III + 2.0 H+ + oxygen --> 2.0 carbon dioxide + 2.0 H2O + protoporphyrinogen 0.0 r_0306_EXP_1 CTP synthase (glutamine) 0.5634796238244514 prot_P28274 + ATP + H2O + L-glutamine + UTP --> ADP + CTP + 2.0 H+ + L-glutamate + phosphate 0.0 r_0306_EXP_2 CTP synthase (glutamine) 0.5617467781260884 prot_P38627 + ATP + H2O + L-glutamine + UTP --> ADP + CTP + 2.0 H+ + L-glutamate + phosphate 0.0 r_0307_EXP_1 CTP synthase (NH3) 0.5634796238244514 prot_P28274 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.0 -r_0307_EXP_2 CTP synthase (NH3) 0.5617467781260884 prot_P38627 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.004327623918448699 +r_0307_EXP_2 CTP synthase (NH3) 0.5617467781260884 prot_P38627 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.004327623918448702 r_0308_EXP_1 cystathionine b-lyase 11.285409035409035 prot_P43623 + H2O + L-cystathionine --> ammonium + L-homocysteine + pyruvate 0.0 r_0308_EXP_2 cystathionine b-lyase 15.820512820512821 prot_P53101 + H2O + L-cystathionine --> ammonium + L-homocysteine + pyruvate 0.0 -r_0309 cystathionine beta-synthase 0.7237984496124031 prot_P32582 + L-homocysteine + L-serine --> H2O + L-cystathionine 0.003775049966295471 -r_0310 cystathionine g-lyase 6.5288520564763655 prot_P31373 + H2O + L-cystathionine --> 2-oxobutanoate + ammonium + L-cysteine 0.003775049966295471 +r_0309 cystathionine beta-synthase 0.7237984496124031 prot_P32582 + L-homocysteine + L-serine --> H2O + L-cystathionine 0.0037750499662956034 +r_0310 cystathionine g-lyase 6.5288520564763655 prot_P31373 + H2O + L-cystathionine --> 2-oxobutanoate + ammonium + L-cysteine 0.0037750499662956034 r_0311 cystathionine gamma-synthase 0.16609504132231406 prot_P47164 + L-cysteine + O-acetyl-L-homoserine --> acetate + H+ + L-cystathionine 0.0 r_0312 cysteine synthase 0.05827586206896552 prot_P06106 + hydrogen sulfide + O-acetyl-L-serine --> acetate + L-cysteine 0.0 r_0313 cysteinyl-tRNA synthetase 0.1712245696400626 prot_P53852 + ATP + L-cysteine + tRNA(Cys) --> AMP + Cys-tRNA(Cys) + diphosphate 0.00375594996568427 r_0314 cytidine deaminase 0.34727251593751957 prot_Q06549 + cytidine + H+ + H2O --> ammonium + uridine 0.0 r_0315 cytidine kinase (GTP) 3.6366925064599482 prot_P27515 + cytidine + GTP --> CMP + GDP + H+ 0.0 -r_0317 cytochrome P450 lanosterol 14-alpha-demethylase (NADP) 2.53 prot_P10614 + 3.1988333333333334 prot_P16603 + 2.0 H+ + lanosterol + 3.0 NADPH + 3.0 oxygen --> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 4.0 H2O + 3.0 NADP(+) 0.003724620677183001 +r_0317 cytochrome P450 lanosterol 14-alpha-demethylase (NADP) 2.53 prot_P10614 + 3.1988333333333334 prot_P16603 + 2.0 H+ + lanosterol + 3.0 NADPH + 3.0 oxygen --> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 4.0 H2O + 3.0 NADP(+) 0.003724620677466421 r_0318 cytosine deaminase 0.028606209150326797 prot_Q12178 + cytosine + H+ + H2O --> ammonium + uracil 0.0 r_0319 D-arabinono-1,4-lactone oxidase 0.790723019670388 prot_P54783 + D-arabinono-1,4-lactone + oxygen --> dehydro-D-arabinono-1,4-lactone + H+ + hydrogen peroxide 0.0 r_0320 D-arabinose 1-dehydrogenase (NAD) 4.371122252366052 prot_Q04212 + D-arabinose + NAD --> D-arabinono-1,4-lactone + H+ + NADH 0.0 @@ -468,20 +468,20 @@ r_0341 dihydroceramidase 2.6755547192301745 prot_Q02896 + cerotic acid + sphinga r_0341_REV dihydroceramidase (reversible) 64.05862892989363 prot_Q02896 + ceramide-1 (C26) + H2O --> cerotic acid + sphinganine 0.0 r_0342 dihydroceramidase 31.281410816343165 prot_Q02896 + ceramide-2 (C24) + H2O --> lignoceric acid + phytosphingosine 0.0 r_0343 dihydroceramidase 31.281410816343165 prot_Q02896 + ceramide-2 (C26) + H2O --> cerotic acid + phytosphingosine 0.0 -r_0344 dihydrofolate reductase 0.030913608562691132 prot_P07807 + dihydrofolic acid + H+ + NADPH --> NADP(+) + THF 0.00036633999407058575 +r_0344 dihydrofolate reductase 0.030913608562691132 prot_P07807 + dihydrofolic acid + H+ + NADPH --> NADP(+) + THF 0.00036633999407064126 r_0345 dihydrofolate reductase 0.030913608562691132 prot_P07807 + dihydrofolic acid + H+ + NADPH --> NADP(+) + THF 0.0 -r_0346 dihydrofolate synthase 1.4510179534077177 prot_Q12676 + 7,8-dihydropteroate + ATP + L-glutamate --> ADP + dihydrofolic acid + H+ + phosphate 6.3400002545677125e-06 -r_0347 dihydroneopterin aldolase 25.866666666666667 prot_P53848 + 7,8-dihydroneopterin --> 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + glycolaldehyde 6.3400002545677125e-06 +r_0346 dihydrofolate synthase 1.4510179534077177 prot_Q12676 + 7,8-dihydropteroate + ATP + L-glutamate --> ADP + dihydrofolic acid + H+ + phosphate 6.340000254623224e-06 +r_0347 dihydroneopterin aldolase 25.866666666666667 prot_P53848 + 7,8-dihydroneopterin --> 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + glycolaldehyde 6.340000254623224e-06 r_0348 dihydroneopterin monophosphate dephosphorylase 1.3136097495034373 prot_Q12154 + 7,8-dihydroneopterin 3'-phosphate + H2O --> 7,8-dihydroneopterin + phosphate 0.0 r_0349 dihydroorotase 5.893713450292398 prot_P20051 + (S)-dihydroorotate + H2O --> H+ + N-carbamoyl-L-aspartate 0.0 -r_0349_REV dihydroorotase (reversible) 0.17974406991260924 prot_P20051 + H+ + N-carbamoyl-L-aspartate --> (S)-dihydroorotate + H2O 0.010726833614579979 +r_0349_REV dihydroorotase (reversible) 0.17974406991260924 prot_P20051 + H+ + N-carbamoyl-L-aspartate --> (S)-dihydroorotate + H2O 0.010726833614579982 r_0350 dihydropteroate synthase 237.30886850152908 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + 4-aminobenzoate --> 7,8-dihydropteroate + H2O 0.0 -r_0351 dihydropteroate synthase 237.30886850152908 prot_P53848 + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + 4-aminobenzoate --> 7,8-dihydropteroate + diphosphate 6.3400002545677125e-06 -r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.23036133098798006 prot_P39522 + (R)-2,3-dihydroxy-3-methylbutanoate --> 3-methyl-2-oxobutanoate + H2O 0.06773178437260571 +r_0351 dihydropteroate synthase 237.30886850152908 prot_P53848 + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + 4-aminobenzoate --> 7,8-dihydropteroate + diphosphate 6.340000254623224e-06 +r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.23036133098798006 prot_P39522 + (R)-2,3-dihydroxy-3-methylbutanoate --> 3-methyl-2-oxobutanoate + H2O 0.06773178437260584 r_0353 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate) 1.419625112917796 prot_P39522 + (2R,3R)-2,3-dihydroxy-3-methylpentanoate --> (S)-3-methyl-2-oxopentanoate + H2O 0.0265490320174191 r_0354_EXP_1 dihydroxyacetone kinase 0.7185562956795263 prot_P43550 + ATP + glycerone --> ADP + dihydroxyacetone phosphate + H+ 0.0 r_0354_EXP_2 dihydroxyacetone kinase 0.719388935146637 prot_P54838 + ATP + glycerone --> ADP + dihydroxyacetone phosphate + H+ 0.0 -r_0355 dimethylallyltranstransferase 10.222979797979797 prot_P08524 + isopentenyl diphosphate + prenyl diphosphate(3-) --> diphosphate + geranyl diphosphate 0.007449241354366002 +r_0355 dimethylallyltranstransferase 10.222979797979797 prot_P08524 + isopentenyl diphosphate + prenyl diphosphate(3-) --> diphosphate + geranyl diphosphate 0.007449241354932842 r_0356 diphosphoglyceromutase 0.013314525462962964 prot_P00950 + 1,3-bisphospho-D-glycerate --> 2,3-bisphospho-D-glyceric acid + H+ 0.0 r_0356_REV diphosphoglyceromutase (reversible) 0.013314525462962964 prot_P00950 + 2,3-bisphospho-D-glyceric acid + H+ --> 1,3-bisphospho-D-glycerate 0.0 r_0357 diphosphoinositol-1,3,4,6-tetrakisphosphate diphosphohydrolase 2396.8888888888887 prot_Q99321 + 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + 3.0 H2O --> 3.0 H+ + myo-inositol 1,3,4,5,6-pentakisphosphate + 3.0 phosphate 0.0 @@ -498,7 +498,7 @@ r_0364_EXP_1 dUTP diphosphatase 0.006082204603017289 prot_P47119 + dUTP + H2O -- r_0364_EXP_2 dUTP diphosphatase 0.4429108796296296 prot_P33317 + dUTP + H2O --> diphosphate + dUMP + H+ 0.0 r_0365 endopolygalacturonase 1.7035361842105263 prot_P47180 + H2O + pectin --> D-galacturonate 0.0 r_0366_EXP_1 enolase 0.05715942028985507 prot_P0CX11 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 -r_0366_EXP_2 enolase 0.056541062801932364 prot_P00924 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 3.2661290145912427 +r_0366_EXP_2 enolase 0.056541062801932364 prot_P00924 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 3.233266060938113 r_0366_EXP_3 enolase 0.18354460093896713 prot_P00925 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 r_0366_EXP_4 enolase 0.057141304347826084 prot_P42222 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 r_0366_EXP_5 enolase 0.05715942028985507 prot_P0CX10 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 @@ -529,32 +529,32 @@ r_0412_REV fatty-acid--CoA ligase (tetradecanoate) (reversible) 33.7398594538402 r_0436 ferrochelatase 8.096586782861293 prot_P16622 + iron(2+) + protoporphyrin --> ferroheme b + 2.0 H+ 0.0 r_0437_EXP_1 ferrocytochrome-c:hydrogen-peroxide oxidoreductase 0.003481111111111111 prot_P00045 + 0.011209166666666666 prot_P00431 + 2.0 ferrocytochrome c + hydrogen peroxide --> 2.0 ferricytochrome c + 2.0 H2O 0.0 r_0437_EXP_2 ferrocytochrome-c:hydrogen-peroxide oxidoreductase 0.003383888888888889 prot_P00044 + 0.011209166666666666 prot_P00431 + 2.0 ferrocytochrome c + hydrogen peroxide --> 2.0 ferricytochrome c + 2.0 H2O 0.0 -r_0438_EXP_1 ferrocytochrome-c:oxygen oxidoreductase 0.0025292407050374562 prot_P00045 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003470743090051798 prot_P00425 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_2 ferrocytochrome-c:oxygen oxidoreductase 0.0025292407050374562 prot_P00045 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003459239202389243 prot_P00424 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 2.403872296406759 -r_0438_EXP_3 ferrocytochrome-c:oxygen oxidoreductase 0.002458602798337559 prot_P00044 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003470743090051798 prot_P00425 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_4 ferrocytochrome-c:oxygen oxidoreductase 0.002458602798337559 prot_P00044 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003459239202389243 prot_P00424 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_5 ferrocytochrome-c:oxygen oxidoreductase 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.0014052906981468086 prot_P07255 + 0.006870848273403699 prot_P19516 + 0.003495163623510905 prot_P38824 + 0.0028410566074698585 prot_P47081 + 0.007194975353860941 prot_P53239 + 0.004794901106789011 prot_Q04935 + 0.0022412398682924474 prot_Q3E731 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 17.02228668115729 -r_0439_EXP_1 ubiquinol:ferricytochrome c reductase 0.011983406387337664 prot_P00045 + 0.01650156750927913 prot_P00127 + 0.013927410950492583 prot_P00128 + 0.041744940093010934 prot_P00163 + 0.03256422793814109 prot_P07143 + 0.04802924800695788 prot_P07256 + 0.03870605839025327 prot_P07257 + 0.022342187219928544 prot_P08067 + 0.010494564722393141 prot_P08525 + 0.007148734930716276 prot_P22289 + 0.008216837782188999 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 3.7848091217467004 -r_0439_EXP_2 ubiquinol:ferricytochrome c reductase 0.01164872778571237 prot_P00044 + 0.01650156750927913 prot_P00127 + 0.013927410950492583 prot_P00128 + 0.041744940093010934 prot_P00163 + 0.03256422793814109 prot_P07143 + 0.04802924800695788 prot_P07256 + 0.03870605839025327 prot_P07257 + 0.022342187219928544 prot_P08067 + 0.010494564722393141 prot_P08525 + 0.007148734930716276 prot_P22289 + 0.008216837782188999 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 5.902529827741736 +r_0438_EXP_1 ferrocytochrome-c:oxygen oxidoreductase 0.0010737358074137757 prot_P00045 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0014734307915811285 prot_P00425 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_2 ferrocytochrome-c:oxygen oxidoreductase 0.0010737358074137757 prot_P00045 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.001468547058655611 prot_P00424 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_3 ferrocytochrome-c:oxygen oxidoreductase 0.0010437479736605981 prot_P00044 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0014734307915811285 prot_P00425 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_4 ferrocytochrome-c:oxygen oxidoreductase 0.0010437479736605981 prot_P00044 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.001468547058655611 prot_P00424 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 19.508861175609596 +r_0438_EXP_5 ferrocytochrome-c:oxygen oxidoreductase 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0005965865326382158 prot_P07255 + 0.0029168737494090794 prot_P19516 + 0.001483798014107227 prot_P38824 + 0.0012061106735528025 prot_P47081 + 0.00305447506657366 prot_P53239 + 0.0020355741551656946 prot_Q04935 + 0.0009514711252258203 prot_Q3E731 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0439_EXP_1 ubiquinol:ferricytochrome c reductase 0.0023972378816698543 prot_P00045 + 0.003301079965207204 prot_P00127 + 0.002786129089253226 prot_P00128 + 0.00835092698389556 prot_P00163 + 0.006514358128013637 prot_P07143 + 0.009608080459664334 prot_P07256 + 0.007743009493634883 prot_P07257 + 0.004469475191925961 prot_P08067 + 0.0020994003950946896 prot_P08525 + 0.0014300790299524282 prot_P22289 + 0.001643749211393956 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 0.0 +r_0439_EXP_2 ubiquinol:ferricytochrome c reductase 0.002330286616222643 prot_P00044 + 0.003301079965207204 prot_P00127 + 0.002786129089253226 prot_P00128 + 0.00835092698389556 prot_P00163 + 0.006514358128013637 prot_P07143 + 0.009608080459664334 prot_P07256 + 0.007743009493634883 prot_P07257 + 0.004469475191925961 prot_P08067 + 0.0020994003950946896 prot_P08525 + 0.0014300790299524282 prot_P22289 + 0.001643749211393956 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 9.68215779277714 r_0440 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 9.99999974737875e-07 r_0441 FMN reductase 0.10556051587301588 prot_Q07923 + FMN + 2.0 H+ + NADH --> FMNH2 + NAD 0.0 r_0442 FMN reductase 0.10556051587301588 prot_Q07923 + FMN + 2.0 H+ + NADPH --> FMNH2 + NADP(+) 0.0 r_0443 formaldehyde dehydrogenase 8.906684027777779 prot_P32771 + formaldehyde + glutathione + NAD --> H+ + NADH + S-formylglutathione 0.0 r_0445 formate dehydrogenase 0.012874691358024692 prot_Q08911 + formate + NAD --> carbon dioxide + NADH 0.0 r_0446 formate-tetrahydrofolate ligase 0.3982132433666004 prot_P07245 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.0 -r_0446_REV formate-tetrahydrofolate ligase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.3100232349035625 +r_0446_REV formate-tetrahydrofolate ligase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.31002323490327893 r_0447 formate-tetrahydrofolate ligase 0.42978473739580797 prot_P09440 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.0 r_0447_REV formate-tetrahydrofolate ligase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.0 r_0448_EXP_1 fructose-2,6-bisphosphate 2-phosphatase 5.915698747876994 prot_Q06137 + beta-D-fructose 2,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 r_0448_EXP_2 fructose-2,6-bisphosphate 2-phosphatase 146.09722222222223 prot_P32604 + beta-D-fructose 2,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 r_0449 fructose-bisphosphatase 0.15249083373186673 prot_P09201 + D-fructose 1,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 -r_0450 fructose-bisphosphate aldolase 0.166213415970673 prot_P14540 + D-fructose 1,6-bisphosphate --> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate 1.9011565964717327 +r_0450 fructose-bisphosphate aldolase 0.166213415970673 prot_P14540 + D-fructose 1,6-bisphosphate --> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate 1.9045739219918443 r_0450_REV fructose-bisphosphate aldolase (reversible) 0.33864102564102566 prot_P14540 + dihydroxyacetone phosphate + glyceraldehyde 3-phosphate --> D-fructose 1,6-bisphosphate 0.0 -r_0451 fumarase 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 1.4169580512683144 +r_0451 fumarase 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 1.4203753767879987 r_0451_REV fumarase (reversible) 0.014265163714439076 prot_P08417 + (S)-malate --> fumarate + H2O 0.0 -r_0452 fumarase, cytoplasmic 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.05371909541229343 +r_0452 fumarase, cytoplasmic 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.04346711885236103 r_0452_REV fumarase, cytoplasmic (reversible) 0.014265163714439076 prot_P08417 + (S)-malate --> fumarate + H2O 0.0 -r_0453 dihydoorotic acid dehydrogenase 1.1372875816993464 prot_P28272 + (S)-dihydroorotate + fumarate --> orotate + succinate 0.010726833614579979 +r_0453 dihydoorotic acid dehydrogenase 1.1372875816993464 prot_P28272 + (S)-dihydroorotate + fumarate --> orotate + succinate 0.010726833614579982 r_0454 fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.0 r_0454_REV fumarate reductase (reversible) 0.9170995670995671 prot_P32614 + FAD + H+ + succinate --> FADH2 + fumarate 0.0 r_0455 soluble fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.0 @@ -562,25 +562,25 @@ r_0455_REV soluble fumarate reductase (reversible) 0.9170995670995671 prot_P3261 r_0457 g-glutamyltransferase 17.374169040835707 prot_Q05902 + glutathione + L-alanine --> L-cysteinylglycine + L-gamma-glutamyl-L-alanine 0.0 r_0458 galactokinase 0.7217737917289487 prot_P04385 + ATP + D-galactose --> ADP + alpha-D-galactose 1-phosphate + H+ 0.0 r_0459 galactose-1-phosphate uridylyltransferase 0.3270447530864197 prot_P08431 + alpha-D-galactose 1-phosphate + H+ + UTP --> diphosphate + UDP-D-galactose 0.0 -r_0460 gamma-glutamylcysteine synthetase 0.00213319158216116 prot_P32477 + ATP + L-cysteine + L-glutamate --> ADP + H+ + L-gamma-glutamyl-L-cysteine + phosphate 9.999999999940612e-08 +r_0460 gamma-glutamylcysteine synthetase 0.00213319158216116 prot_P32477 + ATP + L-cysteine + L-glutamate --> ADP + H+ + L-gamma-glutamyl-L-cysteine + phosphate 1.0000000000287557e-07 r_0461 geranylgeranyltranstransferase 0.6162073031087573 prot_standard + geranylgeranyl diphosphate + isopentenyl diphosphate --> diphosphate + pentaprenyl diphosphate 0.0 -r_0462 geranyltranstransferase 10.222979797979797 prot_P08524 + geranyl diphosphate + isopentenyl diphosphate --> farnesyl diphosphate + diphosphate 0.007449241354366002 +r_0462 geranyltranstransferase 10.222979797979797 prot_P08524 + geranyl diphosphate + isopentenyl diphosphate --> farnesyl diphosphate + diphosphate 0.007449241354932842 r_0463 glucan 1,4-alpha-glucosidase 44.78465926163774 prot_Q06625 + glycogen + H2O --> D-glucose 0.0 r_0464 glucan 1,4-alpha-glucosidase, vacuole 0.05205199864498645 prot_P08019 + glycogen + H2O --> D-glucose 0.0 r_0465 glucosamine-6-phosphate deaminase 0.1225001911377612 prot_standard + alpha-D-glucosamine 6-phosphate + H2O --> ammonium + D-fructose 6-phosphate 0.0 -r_0466 glucose 6-phosphate dehydrogenase 0.025250210703750525 prot_P11412 + D-glucose 6-phosphate + NADP(+) --> 6-O-phosphono-D-glucono-1,5-lactone + H+ + NADPH 6.34934813059651e-13 -r_0467 glucose-6-phosphate isomerase 0.024857664233576642 prot_P12709 + D-glucose 6-phosphate --> D-fructose 6-phosphate 2.0122689809052674 +r_0466 glucose 6-phosphate dehydrogenase 0.025250210703750525 prot_P11412 + D-glucose 6-phosphate + NADP(+) --> 6-O-phosphono-D-glucono-1,5-lactone + H+ + NADPH 0.0 +r_0467 glucose-6-phosphate isomerase 0.024857664233576642 prot_P12709 + D-glucose 6-phosphate --> D-fructose 6-phosphate 2.0122689809058234 r_0467_REV glucose-6-phosphate isomerase (reversible) 0.024857664233576642 prot_P12709 + D-fructose 6-phosphate --> D-glucose 6-phosphate 0.0 r_0468 glutamate 5-kinase 1.0234809027777778 prot_P32264 + ATP + L-glutamate --> ADP + L-gamma-glutamyl phosphate 0.006338001804103973 r_0469 glutamate decarboxylase 34.13511276639768 prot_Q04792 + H+ + L-glutamate --> carbon dioxide + gamma-aminobutyrate 0.0 r_0470 glutamate dehydrogenase (NAD) 1.4390277777777778 prot_P33327 + H2O + L-glutamate + NAD --> 2-oxoglutarate + ammonium + H+ + NADH 0.0 r_0471_EXP_1 glutamate dehydrogenase (NADP) 0.5307169380898228 prot_P39708 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.0 -r_0471_EXP_2 glutamate dehydrogenase (NADP) 0.5301073734280234 prot_P07262 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.8682519439347083 +r_0471_EXP_2 glutamate dehydrogenase (NADP) 0.5301073734280234 prot_P07262 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.8682519439345084 r_0472 glutamate synthase (NADH2) 0.9448492063492063 prot_Q12680 + 2-oxoglutarate + H+ + L-glutamine + NADH --> 2.0 L-glutamate + NAD 0.0 r_0473 glutamate-5-semialdehyde dehydrogenase 0.2646166013940106 prot_P54885 + H+ + L-gamma-glutamyl phosphate + NADPH --> L-glutamic 5-semialdehyde + NADP(+) + phosphate 0.006338001804103973 r_0475_EXP_1 glutaminase 0.0011171565228214292 prot_P43544 + H2O + L-glutamine --> ammonium + L-glutamate 0.0 r_0475_EXP_2 glutaminase 0.0011205348411301363 prot_P53823 + H2O + L-glutamine --> ammonium + L-glutamate 0.0 -r_0476 glutamine synthetase 0.029297138047138047 prot_P32288 + ammonium + ATP + L-glutamate --> ADP + H+ + L-glutamine + phosphate 0.10449512025995522 +r_0476 glutamine synthetase 0.029297138047138047 prot_P32288 + ammonium + ATP + L-glutamate --> ADP + H+ + L-glutamine + phosphate 0.1044951202604493 r_0477 glutamine-fructose-6-phosphate transaminase 0.6263458528951487 prot_P14742 + D-fructose 6-phosphate + L-glutamine --> alpha-D-glucosamine 6-phosphate + L-glutamate 0.0023610000000000003 r_0478 glutaminyl-tRNA synthetase 15.369603878657363 prot_P13188 + ATP + L-glutamine + tRNA(Gln) --> AMP + diphosphate + Gln-tRNA(Gln) 0.0141160332291015 r_0479 glutamyl-tRNA synthetase 4.974688861932783 prot_P46655 + ATP + L-glutamate + tRNA(Glu) --> AMP + diphosphate + Glu-tRNA(Glu) 0.029648731201628798 @@ -597,10 +597,10 @@ r_0483_EXP_4 glutathione peridoxase 0.0038546223388743073 prot_P17695 + 2.0 glut r_0483_EXP_5 glutathione peridoxase 0.2725292397660819 prot_P40581 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0483_EXP_6 glutathione peridoxase 0.3697285294019552 prot_P36014 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0484 glutathione peroxidase, mitochondria 1.0350179133060056 prot_Q02784 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 -r_0485 glutathione synthetase 0.2818939393939394 prot_Q08220 + ATP + L-gamma-glutamyl-L-cysteine + L-glycine --> ADP + glutathione + H+ + phosphate 9.999999999940612e-08 +r_0485 glutathione synthetase 0.2818939393939394 prot_Q08220 + ATP + L-gamma-glutamyl-L-cysteine + L-glycine --> ADP + glutathione + H+ + phosphate 1.0000000000287557e-07 r_0486_EXP_1 glyceraldehyde-3-phosphate dehydrogenase 1.091178266178266 prot_P00359 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 0.0 r_0486_EXP_2 glyceraldehyde-3-phosphate dehydrogenase 0.1416581138487952 prot_P00360 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 3.4018794517052906 -r_0486_EXP_3 glyceraldehyde-3-phosphate dehydrogenase 0.5962574850299401 prot_P00358 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 0.2670940337985613 +r_0486_EXP_3 glyceraldehyde-3-phosphate dehydrogenase 0.5962574850299401 prot_P00358 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 0.23423108014473532 r_0486_REV_EXP_1 glyceraldehyde-3-phosphate dehydrogenase (reversible) 1.091178266178266 prot_P00359 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 r_0486_REV_EXP_2 glyceraldehyde-3-phosphate dehydrogenase (reversible) 0.3424329501915709 prot_P00360 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 r_0486_REV_EXP_3 glyceraldehyde-3-phosphate dehydrogenase (reversible) 0.5962574850299401 prot_P00358 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 @@ -609,19 +609,19 @@ r_0488 glycerol kinase 0.013277445109780439 prot_P32190 + ATP + glycerol --> ADP r_0489_EXP_1 glycerol-3-phosphatase 0.6923038630027878 prot_P40106 + glycerol 3-phosphate + H2O --> glycerol + phosphate 0.06402693448 r_0489_EXP_2 glycerol-3-phosphatase 0.6956142970927918 prot_P41277 + glycerol 3-phosphate + H2O --> glycerol + phosphate 0.0 r_0490 glycerol-3-phosphate dehydrogenase (fad) 0.6038455121788456 prot_P32191 + FAD + glycerol 3-phosphate + H+ --> dihydroxyacetone phosphate + FADH2 0.0 -r_0491_EXP_1 glycerol-3-phosphate dehydrogenase (NAD) 0.10538102261553589 prot_Q00055 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.07098186724424138 +r_0491_EXP_1 glycerol-3-phosphate dehydrogenase (NAD) 0.10538102261553589 prot_Q00055 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.07098186724421478 r_0491_EXP_2 glycerol-3-phosphate dehydrogenase (NAD) 0.1214896755162242 prot_P41911 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.0 r_0492 glycerol-3-phosphate dehydrogenase (NAD) 0.1214896755162242 prot_P41911 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.0 r_0497 glycerophosphodiester phosphodiesterase (glycerophosphocholine) 0.174260101010101 prot_Q02979 + H2O + sn-glycero-3-phosphocholine --> choline + glycerol 3-phosphate + H+ 0.0 -r_0499 glycinamide ribotide transformylase 0.1634722222222222 prot_P04161 + 10-formyl-THF + 5-phospho-ribosyl-glycineamide --> 5'-phosphoribosyl-N-formylglycineamide + H+ + THF 0.010240426385259176 +r_0499 glycinamide ribotide transformylase 0.1634722222222222 prot_P04161 + 10-formyl-THF + 5-phospho-ribosyl-glycineamide --> 5'-phosphoribosyl-N-formylglycineamide + H+ + THF 0.01024042638550752 r_0500 glycine C-acetyltransferase 0.062476381011109826 prot_standard + coenzyme A + L-2-amino-3-oxobutanoate --> acetyl-CoA + L-glycine 0.0 r_0501 glycine cleavage system 0.17131712790948955 prot_P09624 + 0.05961049407152449 prot_P39726 + 0.14105353380868527 prot_P48015 + 0.3630330791773559 prot_P49095 + L-glycine + NAD + THF --> 5,10-methylenetetrahydrofolate + ammonium + carbon dioxide + NADH 0.0 -r_0502 glycine hydroxymethyltransferase 0.0226640625 prot_P37291 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 0.361476268911848 +r_0502 glycine hydroxymethyltransferase 0.0226640625 prot_P37291 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 0.3614762689112561 r_0502_REV glycine hydroxymethyltransferase (reversible) 63.06521739130435 prot_P37291 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF 0.0 -r_0503 glycine hydroxymethyltransferase 0.023301215277777777 prot_P37292 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 1.8993174938957644e-05 -r_0503_REV glycine hydroxymethyltransferase (reversible) 64.83816425120773 prot_P37292 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF -6.825672243687903e-09 +r_0503 glycine hydroxymethyltransferase 0.023301215277777777 prot_P37292 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 1.89931749390864e-05 +r_0503_REV glycine hydroxymethyltransferase (reversible) 64.83816425120773 prot_P37292 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF -6.825672243734174e-09 r_0504 glycine-cleavage complex (lipoamide) 0.023116760828625234 prot_P09624 + 0.00804357130628317 prot_P39726 + 0.019033127889060093 prot_P48015 + 0.048986046909775725 prot_P49095 + H+ + L-glycine + lipoamide --> carbon dioxide + S(8)-aminomethyldihydrolipoamide 0.0 -r_0505_EXP_1 glycine-cleavage complex (lipoamide) 0.016688295637127672 prot_P09624 + 0.005806760598195526 prot_P39726 + 0.013740266963292547 prot_P48015 + 0.0353636756890372 prot_P49095 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 1.4169580512683144 +r_0505_EXP_1 glycine-cleavage complex (lipoamide) 0.016688295637127672 prot_P09624 + 0.005806760598195526 prot_P39726 + 0.013740266963292547 prot_P48015 + 0.0353636756890372 prot_P49095 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 1.4203753767879987 r_0505_EXP_2 glycine-cleavage complex (lipoamide) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 0.0 r_0506 glycine-cleavage complex (lipoylprotein) 0.04357695209331861 prot_P09624 + 0.015162778387145652 prot_P39726 + 0.0358789757940712 prot_P48015 + 0.09234263551254228 prot_P49095 + L-glycine + lipoylprotein --> carbon dioxide + S(8)-aminomethyldihydrolipoylprotein 0.0 r_0507 glycine-cleavage complex (lipoylprotein) 0.2838103427329358 prot_P09624 + 0.0987529674315879 prot_P39726 + 0.23367454417683617 prot_P48015 + 0.6014141369399599 prot_P49095 + H+ + S(8)-aminomethyldihydrolipoylprotein + THF --> 5,10-methylenetetrahydrofolate + ammonium + dihydrolipoylprotein 0.0 @@ -634,7 +634,7 @@ r_0510_EXP_4 glycogen (starch) synthase 18.96007470955954 prot_P27472 + 16.50835 r_0511 glycogen phosphorylase 0.568069306930693 prot_P06738 + glycogen + phosphate --> D-glucose 1-phosphate 0.0 r_0512_EXP_1 glycyl-tRNA synthetase 29.750380517503807 prot_P38088 + ATP + L-glycine + tRNA(Gly) --> AMP + diphosphate + Gly-tRNA(Gly) 0.0 r_0512_EXP_2 glycyl-tRNA synthetase 1.2407058001397624 prot_Q06817 + ATP + L-glycine + tRNA(Gly) --> AMP + diphosphate + Gly-tRNA(Gly) 0.0283748983111195 -r_0514 GMP synthase 0.0098038624019312 prot_P38625 + ATP + H2O + L-glutamine + xanthosine-5-phosphate --> AMP + diphosphate + GMP + 2.0 H+ + L-glutamate 0.004799823201108194 +r_0514 GMP synthase 0.0098038624019312 prot_P38625 + ATP + H2O + L-glutamine + xanthosine-5-phosphate --> AMP + diphosphate + GMP + 2.0 H+ + L-glutamate 0.00479982320110825 r_0518 GPI-anchor assembly, step 2 149.73523909383033 prot_P23797 + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O --> 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate + H+ 0.0 r_0518_REV GPI-anchor assembly, step 2 (reversible) 60.09087553078704 prot_P23797 + 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate + H+ --> 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O 0.0 r_0519 GPI-anchor assembly, step 5 1.0741619906421145 prot_P25580 + 1.0571943419782979 prot_P47088 + 6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol + dolichyl D-mannosyl phosphate --> 6-O-[alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + dolichyl phosphate 0.0 @@ -649,11 +649,11 @@ r_0523_EXP_1 GPI-anchor assembly, step 9 0.007109647641562535 prot_Q06636 + 6-O- r_0523_EXP_2 GPI-anchor assembly, step 9 0.03254362265000563 prot_Q07830 + 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone --> 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone 0.0 r_0523_REV_EXP_1 GPI-anchor assembly, step 9 (reversible) 0.007109647641562535 prot_Q06636 + 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone --> 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone 0.0 r_0523_REV_EXP_2 GPI-anchor assembly, step 9 (reversible) 0.03254362265000563 prot_Q07830 + 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone --> 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone 0.0 -r_0524 GTP cyclohydrolase I 197.7849002849003 prot_P51601 + GTP + H2O --> 7,8-dihydroneopterin 3'-triphosphate + formate + H+ 6.3400002545677125e-06 +r_0524 GTP cyclohydrolase I 197.7849002849003 prot_P51601 + GTP + H2O --> 7,8-dihydroneopterin 3'-triphosphate + formate + H+ 6.340000254623224e-06 r_0525 GTP cyclohydrolase II 0.024647633744855967 prot_P38066 + GTP + 3.0 H2O --> 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + diphosphate + formate + 2.0 H+ 9.999999710998968e-05 r_0526 guanine deaminase 1.7229712858926343 prot_Q07729 + guanine + H+ + H2O --> 9H-xanthine + ammonium 0.0 r_0527 guanine phosphoribosyltransferase 0.09123207301173403 prot_Q04178 + guanine + PRPP --> diphosphate + GMP 0.0 -r_0528 guanylate kinase 0.014549492385786802 prot_P15454 + ATP + GMP --> ADP + GDP 0.00034634000876395364 +r_0528 guanylate kinase 0.014549492385786802 prot_P15454 + ATP + GMP --> ADP + GDP 0.00034634000876400915 r_0529 guanylate kinase (GMP:dATP) 0.014549492385786802 prot_P15454 + dATP + GMP --> dADP + GDP 0.0 r_0529_REV guanylate kinase (GMP:dATP) (reversible) 0.014549492385786802 prot_P15454 + dADP + GDP --> dATP + GMP 0.0 r_0530_EXP_1 heme O monooxygenase 0.5821949882086304 prot_P40086 + heme o + NADH + oxygen --> H2O + heme a + NAD 0.0 @@ -686,23 +686,23 @@ r_0543_EXP_2 homocitrate synthase 21.204303979830723 prot_P48570 + 2-oxoglutarat r_0544_EXP_1 homocysteine S-methyltransferase 26.83845029239766 prot_Q12525 + L-homocysteine + S-adenosyl-L-methionine --> H+ + L-methionine + S-adenosyl-L-homocysteine 0.0 r_0544_EXP_2 homocysteine S-methyltransferase 26.80482456140351 prot_Q08985 + L-homocysteine + S-adenosyl-L-methionine --> H+ + L-methionine + S-adenosyl-L-homocysteine 0.0 r_0545 homoisocitrate dehydrogenase 0.6547222222222222 prot_P40495 + homoisocitrate + NAD --> 2-oxoadipic acid + carbon dioxide + NADH 0.032939964005654 -r_0546 homoserine dehydrogenase (NADH) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADH --> L-homoserine + NAD 0.03579652043784406 +r_0546 homoserine dehydrogenase (NADH) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADH --> L-homoserine + NAD 0.03579652043784409 r_0547 homoserine dehydrogenase (NADP) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADPH --> L-homoserine + NADP(+) 0.0 -r_0548 homoserine kinase 0.263562091503268 prot_P17423 + ATP + L-homoserine --> ADP + H+ + O-phospho-L-homoserine 0.02387172382427442 -r_0549 homoserine O-trans-acetylase 0.9806103801169591 prot_P08465 + acetyl-CoA + L-homoserine --> coenzyme A + O-acetyl-L-homoserine 0.011924796613569637 +r_0548 homoserine kinase 0.263562091503268 prot_P17423 + ATP + L-homoserine --> ADP + H+ + O-phospho-L-homoserine 0.023871723824274306 +r_0549 homoserine O-trans-acetylase 0.9806103801169591 prot_P08465 + acetyl-CoA + L-homoserine --> coenzyme A + O-acetyl-L-homoserine 0.011924796613569787 r_0550_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.3160087719298246 prot_Q04120 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0550_EXP_2 hydrogen peroxide reductase (thioredoxin) 0.1642543859649123 prot_P22217 + 0.3160087719298246 prot_Q04120 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0551 hydrogen peroxide reductase (thioredoxin) 0.07592592592592592 prot_P25372 + 0.15517676767676766 prot_P34227 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 -r_0552_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.2794590643274854 prot_P38013 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.01467412387278076 +r_0552_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.2794590643274854 prot_P38013 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.014621833146349733 r_0552_EXP_2 hydrogen peroxide reductase (thioredoxin) 0.1642543859649123 prot_P22217 + 0.2794590643274854 prot_P38013 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 -r_0553 hydroxyacylglutathione hydrolase 0.008888605152650096 prot_Q05584 + (R)-S-lactoylglutathione + H2O --> (R)-lactate + glutathione + H+ 0.0 +r_0553 hydroxyacylglutathione hydrolase 0.008888605152650096 prot_Q05584 + (R)-S-lactoylglutathione + H2O --> (R)-lactate + glutathione + H+ 0.04653225574457277 r_0554 hydroxyacylglutathione hydrolase 0.009175746226308025 prot_Q12320 + (R)-S-lactoylglutathione + H2O --> (R)-lactate + glutathione + H+ 0.0 r_0555 hydroxybenzoate octaprenyltransferase 0.8535401716463751 prot_P32378 + 4-hydroxybenzoate + hexaprenyl diphosphate --> 3-hexaprenyl-4-hydroxybenzoic acid + diphosphate 0.0 r_0556 hydroxyethylthiazole kinase 12.64725296618268 prot_P41835 + 5-(2-hydroxyethyl)-4-methylthiazole + ATP --> 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ 0.0 r_0557 hydroxymethylbilane synthase 163.0 prot_P28789 + H2O + 4.0 porphobilinogen --> 4.0 ammonium + preuroporphyrinogen 0.0 r_0558_EXP_1 hydroxymethylglutaryl CoA reductase 1.5450320512820512 prot_P12684 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.0 -r_0558_EXP_2 hydroxymethylglutaryl CoA reductase 1.544150641025641 prot_P12683 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.022347724063098005 -r_0560 hydroxymethylglutaryl CoA synthase 3.322101449275362 prot_P54839 + acetoacetyl-CoA + acetyl-CoA + H2O --> 3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ 0.022347724063098005 +r_0558_EXP_2 hydroxymethylglutaryl CoA reductase 1.544150641025641 prot_P12683 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.022347724064798527 +r_0560 hydroxymethylglutaryl CoA synthase 3.322101449275362 prot_P54839 + acetoacetyl-CoA + acetyl-CoA + H2O --> 3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ 0.022347724064798527 r_0561_EXP_1 hydroxymethylpyrimidine kinase (ATP) 39.57945736434109 prot_Q08224 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 1.20000004244503e-07 r_0561_EXP_2 hydroxymethylpyrimidine kinase (ATP) 39.62144702842377 prot_Q08975 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 r_0561_EXP_3 hydroxymethylpyrimidine kinase (ATP) 340.09581877502734 prot_Q06490 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 @@ -711,15 +711,15 @@ r_0563 Imidazole-glycerol-3-phosphate synthase 2.4584541062801932 prot_P33734 + r_0564 imidazoleglycerol-phosphate dehydratase 0.004728769841269841 prot_P06633 + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate --> 3-(imidazol-4-yl)-2-oxopropyl dihydrogen phosphate + H2O 0.008356708763266002 r_0565_EXP_1 IMP dehydrogenase 6.383242999096658 prot_P38697 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0 r_0565_EXP_2 IMP dehydrogenase 6.389453477868112 prot_P50095 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0 -r_0565_EXP_3 IMP dehydrogenase 6.367886178861789 prot_P50094 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.004799823201108194 -r_0566 indole-3-glycerol-phosphate synthase 1.550264949662187 prot_P00937 + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ --> 1-C-(indol-3-yl)glycerol 3-phosphate + carbon dioxide + H2O 0.0045086212576769275 +r_0565_EXP_3 IMP dehydrogenase 6.367886178861789 prot_P50094 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.00479982320110825 +r_0566 indole-3-glycerol-phosphate synthase 1.550264949662187 prot_P00937 + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ --> 1-C-(indol-3-yl)glycerol 3-phosphate + carbon dioxide + H2O 0.004508621257677068 r_0567_EXP_1 indole-3-pyruvate decarboxylase 0.27589605734767025 prot_P26263 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 r_0567_EXP_2 indole-3-pyruvate decarboxylase 0.11780651340996169 prot_P06169 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 r_0567_EXP_3 indole-3-pyruvate decarboxylase 0.27738351254480287 prot_P16467 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 -r_0568 inorganic diphosphatase 0.03450854700854701 prot_P00817 + diphosphate + H2O --> H+ + 2.0 phosphate 1.0725587542228485 -r_0569 inorganic diphosphatase 0.03800534188034188 prot_P28239 + diphosphate + H2O --> H+ + 2.0 phosphate 0.0 +r_0568 inorganic diphosphatase 0.03450854700854701 prot_P00817 + diphosphate + H2O --> H+ + 2.0 phosphate 0.9904766225429371 +r_0569 inorganic diphosphatase 0.03800534188034188 prot_P28239 + diphosphate + H2O --> H+ + 2.0 phosphate 0.09232348665073833 r_0570_EXP_1 inosine monophosphate cyclohydrolase 2.10859173126615 prot_P54113 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.0 -r_0570_EXP_2 inosine monophosphate cyclohydrolase 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.018597015148520933 +r_0570_EXP_2 inosine monophosphate cyclohydrolase 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.018597015148769276 r_0570_REV_EXP_1 inosine monophosphate cyclohydrolase (reversible) 2.10859173126615 prot_P54113 + H2O + IMP --> phosphoribosyl-formamido-carboxamide 0.0 r_0570_REV_EXP_2 inosine monophosphate cyclohydrolase (reversible) 2.1079780361757106 prot_P38009 + H2O + IMP --> phosphoribosyl-formamido-carboxamide 0.0 r_0571 inositol-1,3,4,5,6-pentakisphosphate 2-kinase 12.457614290039357 prot_Q06667 + ATP + myo-inositol 1,3,4,5,6-pentakisphosphate --> ADP + H+ + myo-inositol hexakisphosphate 0.0 @@ -789,8 +789,8 @@ r_0654 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol-P-ce r_0655 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol-P-ceramide D (C26) --> 1D-myo-inositol 1-phosphate + ceramide-4 (C26) + 2.0 H+ 0.0 r_0656 isoamyl acetate-hydrolyzing esterase 6.693496157764181 prot_P41734 + H2O + isoamyl acetate --> acetate + H+ + isoamylol 0.0 r_0657 isobutyl acetate-hydrolyzing esterase 9.93658635305908 prot_P41734 + H2O + isobutyl acetate --> acetate + H+ + isobutanol 0.0 -r_0658 isocitrate dehydrogenase (NAD+) 0.5194640522875817 prot_P28241 + 0.5140392156862745 prot_P28834 + isocitrate + NAD --> 2-oxoglutarate + carbon dioxide + NADH 0.0 -r_0659 isocitrate dehydrogenase (NADP) 0.05072113289760349 prot_P41939 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 1.5535005162214965 +r_0658 isocitrate dehydrogenase (NAD+) 0.5194640522875817 prot_P28241 + 0.5140392156862745 prot_P28834 + isocitrate + NAD --> 2-oxoglutarate + carbon dioxide + NADH 0.0631482417411815 +r_0659 isocitrate dehydrogenase (NADP) 0.05072113289760349 prot_P41939 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 1.4937695999999998 r_0659_REV isocitrate dehydrogenase (NADP) (reversible) 2.6395691609977323 prot_P41939 + 2-oxoglutarate + carbon dioxide + NADPH --> isocitrate + NADP(+) 0.0 r_0661 isocitrate dehydrogenase (NADP+), peroxisomal 0.05213071895424837 prot_P53982 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.0 r_0662 isocitrate lyase 1.3133207070707071 prot_P28240 + isocitrate --> glyoxylate + succinate 0.0 @@ -800,13 +800,13 @@ r_0664 isoleucine transaminase 0.011265116279069768 prot_P38891 + 2-oxoglutarate r_0664_REV isoleucine transaminase (reversible) 0.011265116279069768 prot_P38891 + (S)-3-methyl-2-oxopentanoate + L-glutamate --> 2-oxoglutarate + L-isoleucine 0.0 r_0665 isoleucyl-tRNA synthetase 0.4249032614704257 prot_P09436 + ATP + L-isoleucine + tRNA(Ile) --> AMP + diphosphate + Ile-tRNA(Ile) 0.0265490320174191 r_0666 isoleucyl-tRNA synthetase 0.40006218905472635 prot_P48526 + ATP + L-isoleucine + tRNA(Ile) --> AMP + diphosphate + Ile-tRNA(Ile) 0.0 -r_0667 isopentenyl-diphosphate D-isomerase 1.1202472121456402 prot_P15496 + isopentenyl diphosphate --> prenyl diphosphate(3-) 0.007449241354366002 +r_0667 isopentenyl-diphosphate D-isomerase 1.1202472121456402 prot_P15496 + isopentenyl diphosphate --> prenyl diphosphate(3-) 0.007449241354932842 r_0667_REV isopentenyl-diphosphate D-isomerase (reversible) 1.1202472121456402 prot_P15496 + prenyl diphosphate(3-) --> isopentenyl diphosphate 0.0 r_0668 itaconate-CoA ligase (ADP-forming) 0.22156557067271354 prot_P53312 + 0.16549508692365836 prot_P53598 + ATP + coenzyme A + itaconate --> ADP + itaconyl-CoA + phosphate 0.0 r_0668_REV itaconate-CoA ligase (ADP-forming) (reversible) 0.5921843434343435 prot_P53312 + 0.44232323232323234 prot_P53598 + ADP + itaconyl-CoA + phosphate --> ATP + coenzyme A + itaconate 0.0 r_0669 ketol-acid reductoisomerase (2-aceto-2-hydroxybutanoate) 0.6734669095324833 prot_P06168 + (S)-2-acetyl-2-hydroxybutanoate + H+ + NADPH --> (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) 0.0265490320174191 -r_0670 kynureninase 1.2721196709441296 prot_Q05979 + H2O + L-kynurenine --> anthranilate + H+ + L-alanine 4.463981443297198e-05 -r_0671 kynurenine 3-monooxygenase 7.174192665571977 prot_P38169 + H+ + L-kynurenine + NADPH + oxygen --> 3-hydroxy-L-kynurenine + H2O + NADP(+) 0.000606999997398135 +r_0670 kynureninase 1.2721196709441296 prot_Q05979 + H2O + L-kynurenine --> anthranilate + H+ + L-alanine 4.4639814434474794e-05 +r_0671 kynurenine 3-monooxygenase 7.174192665571977 prot_P38169 + H+ + L-kynurenine + NADPH + oxygen --> 3-hydroxy-L-kynurenine + H2O + NADP(+) 0.0006069999973967727 r_0672 L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase 11.932407407407407 prot_P07275 + 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H2O + NAD --> erythro-4-hydroxy-L-glutamic acid + H+ + NADH 0.0 r_0672_REV L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase (reversible) 11.932407407407407 prot_P07275 + erythro-4-hydroxy-L-glutamic acid + H+ + NADH --> 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H2O + NAD 0.0 r_0673 L-4-hydroxyglutamate semialdehyde dehydrogenase 11.932407407407407 prot_P07275 + H2O + L-4-hydroxyglutamic semialdehyde + NAD --> erythro-4-hydroxy-L-glutamic acid + 2.0 H+ + NADH 0.0 @@ -826,18 +826,18 @@ r_0681 L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase 0.0397325741 r_0682 L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase 0.04468167701863354 prot_Q01802 + 2-oxoglutarate + erythro-4-hydroxy-L-glutamic acid --> 4-hydroxy-2-oxoglutarate + L-glutamate 0.0 r_0683 L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase 0.039732574189095926 prot_P23542 + 2-oxoglutarate + erythro-4-hydroxy-L-glutamic acid --> 4-hydroxy-2-oxoglutarate + L-glutamate 0.0 r_0687 L-hydroxyproline reductase (NADP) 0.0020925 prot_P32263 + 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H+ + NADPH --> NADP(+) + trans-4-hydroxy-L-proline 0.0 -r_0688_EXP_1 L-lactaldehyde:NADP+ 1-oxidoreductase 60.65196078431372 prot_P38715 + H+ + methylglyoxal + NADPH --> (S)-lactaldehyde + NADP(+) 0.0020659411325405254 -r_0688_EXP_2 L-lactaldehyde:NADP+ 1-oxidoreductase 2.8890402664244625 prot_Q12068 + H+ + methylglyoxal + NADPH --> (S)-lactaldehyde + NADP(+) 0.02367459816105954 +r_0688_EXP_1 L-lactaldehyde:NADP+ 1-oxidoreductase 60.65196078431372 prot_P38715 + H+ + methylglyoxal + NADPH --> (S)-lactaldehyde + NADP(+) 0.0020659411219022435 +r_0688_EXP_2 L-lactaldehyde:NADP+ 1-oxidoreductase 2.8890402664244625 prot_Q12068 + H+ + methylglyoxal + NADPH --> (S)-lactaldehyde + NADP(+) 0.023674598161182777 r_0689 L-serine deaminase 0.018661443494776827 prot_P25379 + L-serine --> ammonium + pyruvate 0.0 r_0690 L-serine dehydrogenase 0.7363131313131314 prot_Q05016 + L-serine + NADP(+) --> H+ + L-alpha-formylglycine + NADPH 0.0 r_0691 L-sorbitol dehydrogenase (L-sorbose-producing) 0.7983182730923695 prot_P35497 + L-glucitol + NAD --> H+ + L-sorbose + NADH 0.0 -r_0692 L-threonine deaminase 0.007720611346848971 prot_P25379 + L-threonine --> 2-oxobutanoate + ammonium 0.00035442099443431727 +r_0692 L-threonine deaminase 0.007720611346848971 prot_P25379 + L-threonine --> 2-oxobutanoate + ammonium 0.0003544209944342028 r_0693 L-threonine deaminase 0.01253948609146629 prot_P00927 + L-threonine --> 2-oxobutanoate + ammonium 0.0 -r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.3527200202735511 prot_P47125 + L-tryptophan + oxygen --> N-formyl-L-kynurenine 0.000651639811831107 +r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.3527200202735511 prot_P47125 + L-tryptophan + oxygen --> N-formyl-L-kynurenine 0.0006516398118312475 r_0695 L-tyrosine N-formyltransferase 52.20067092135934 prot_P21623 + 10-formyl-THF + L-tyrosine --> H+ + N-formyl-L-tyrosine + THF 0.0 -r_0696 lactaldehyde dehydrogenase 0.033859544541667556 prot_Q12068 + (S)-lactaldehyde + H2O + NAD --> (S)-lactate + 2.0 H+ + NADH 0.02574053929360006 -r_0697 lactoylglutathione lyase 0.005679029304029304 prot_P50107 + glutathione + methylglyoxal --> (R)-S-lactoylglutathione 0.0 -r_0698 lanosterol synthase 24.44598824754819 prot_P38604 + (S)-2,3-epoxysqualene --> lanosterol 0.003724620677183001 +r_0696 lactaldehyde dehydrogenase 0.033859544541667556 prot_Q12068 + (S)-lactaldehyde + H2O + NAD --> (S)-lactate + 2.0 H+ + NADH 0.025740539283085017 +r_0697 lactoylglutathione lyase 0.005679029304029304 prot_P50107 + glutathione + methylglyoxal --> (R)-S-lactoylglutathione 0.04653225574457277 +r_0698 lanosterol synthase 24.44598824754819 prot_P38604 + (S)-2,3-epoxysqualene --> lanosterol 0.003724620677466421 r_0699 leucine transaminase 0.012875835189309577 prot_P47176 + 2-oxoglutarate + L-leucine --> 4-methyl-2-oxopentanoate + L-glutamate 0.0 r_0699_REV leucine transaminase (reversible) 0.010755813953488373 prot_P47176 + 4-methyl-2-oxopentanoate + L-glutamate --> 2-oxoglutarate + L-leucine 0.0362523293945085 r_0700 leucine transaminase 0.013485523385300667 prot_P38891 + 2-oxoglutarate + L-leucine --> 4-methyl-2-oxopentanoate + L-glutamate 0.0 @@ -858,16 +858,16 @@ r_0708 leukotriene A4 hydrolase 1.0690022111663904 prot_Q10740 + H2O + leukotrie r_0708_REV leukotriene A4 hydrolase (reversible) 4.1321047008547005 prot_Q10740 + leukotriene B4 --> H2O + leukotriene A4 0.0 r_0711 lysyl-tRNA synthetase 0.41307439824945297 prot_P15180 + ATP + L-lysine + tRNA(Lys) --> AMP + diphosphate + Lys-tRNA(Lys) 0.032939964005654 r_0712 lysyl-tRNA synthetase 0.40194505227327987 prot_P32048 + ATP + L-lysine + tRNA(Lys) --> AMP + diphosphate + Lys-tRNA(Lys) 0.0 -r_0713 malate dehydrogenase 0.05201038748832867 prot_P17505 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 1.5454656485715652 +r_0713 malate dehydrogenase 0.05201038748832867 prot_P17505 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 1.5488829740907137 r_0713_REV malate dehydrogenase (reversible) 0.05201038748832867 prot_P17505 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.0 r_0714 malate dehydrogenase, cytoplasmic 0.009916009348524686 prot_P22133 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.0 -r_0714_REV malate dehydrogenase, cytoplasmic (reversible) 9.304413377192983e-05 prot_P22133 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.09524154084916688 +r_0714_REV malate dehydrogenase, cytoplasmic (reversible) 9.304413377192983e-05 prot_P22133 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.10563079452118801 r_0715 malate dehydrogenase, peroxisomal 0.009052974973220372 prot_P32419 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.0 -r_0715_REV malate dehydrogenase, peroxisomal (reversible) 8.494608918128655e-05 prot_P32419 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.014955570952334435 +r_0715_REV malate dehydrogenase, peroxisomal (reversible) 8.494608918128655e-05 prot_P32419 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.014818293840356989 r_0716_EXP_1 malate synthase 0.9084780092592593 prot_P21826 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 r_0716_EXP_2 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 r_0717 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 -r_0718 malic enzyme (NAD) 0.15417910447761193 prot_P36013 + (S)-malate + NAD --> carbon dioxide + NADH + pyruvate 0.03540860991054395 +r_0718 malic enzyme (NAD) 0.15417910447761193 prot_P36013 + (S)-malate + NAD --> carbon dioxide + NADH + pyruvate 0.03540860991119099 r_0719 malic enzyme (NADP) 0.15417910447761193 prot_P36013 + (S)-malate + NADP(+) --> carbon dioxide + NADPH + pyruvate 0.0 r_0721 malonyl-CoA-ACP transacylase 0.0018443121693121694 prot_P32463 + 0.0053845238095238095 prot_Q12283 + H+ + malonyl-CoA + ACP1 --> carboxyacetyl-ACP + coenzyme A 0.0 r_0721_REV malonyl-CoA-ACP transacylase (reversible) 0.0018443121693121694 prot_P32463 + 0.0053845238095238095 prot_Q12283 + carboxyacetyl-ACP + coenzyme A --> H+ + malonyl-CoA + ACP1 0.0 @@ -876,23 +876,23 @@ r_0723 mannose-6-phosphate isomerase 0.6692916666666666 prot_P29952 + D-mannose r_0723_REV mannose-6-phosphate isomerase (reversible) 0.09493498817966903 prot_P29952 + D-fructose 6-phosphate --> D-mannose 6-phosphate 0.070204 r_0724 methenyltetrahydrifikate cyclohydrolase 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.0 r_0724_REV methenyltetrahydrifikate cyclohydrolase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O 0.0 -r_0725 methenyltetrahydrofolate cyclohydrolase 1.3619742369207077 prot_P07245 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.3388606764373425 +r_0725 methenyltetrahydrofolate cyclohydrolase 1.3619742369207077 prot_P07245 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.3388606764375557 r_0725_REV methenyltetrahydrofolate cyclohydrolase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O 0.0 -r_0726_EXP_1 methionine adenosyltransferase 1.565037037037037 prot_P19358 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.015434982529254057 +r_0726_EXP_1 methionine adenosyltransferase 1.565037037037037 prot_P19358 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.015434982528449125 r_0726_EXP_2 methionine adenosyltransferase 19.92471888698304 prot_P10659 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.0 -r_0727 methionine synthase 24.2238162581693 prot_P05694 + 5-methyltetrahydrofolate + L-homocysteine --> L-methionine + THF 0.02225559248068932 +r_0727 methionine synthase 24.2238162581693 prot_P05694 + 5-methyltetrahydrofolate + L-homocysteine --> L-methionine + THF 0.022255592479884387 r_0728 methionyl-tRNA formyltransferase 95.33547008547009 prot_P32785 + 10-formyl-THF + Met-tRNA(Met) --> fMet-tRNA(fMet) + H+ + THF 0.0 r_0729 methionyl-tRNA synthetase 0.9519777777777778 prot_P00958 + ATP + L-methionine + tRNA(Met) --> AMP + diphosphate + Met-tRNA(Met) 0.00814974664727417 r_0730 methionyl-tRNA synthetase 0.7414888888888889 prot_P22438 + ATP + L-methionine + tRNA(Met) --> AMP + diphosphate + Met-tRNA(Met) 0.0 -r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 3.4304661673761956 prot_Q02046 + 5,10-methylenetetrahydrofolate + NAD --> 5,10-methenyl-THF + NADH 0.33886067643734274 +r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 3.4304661673761956 prot_Q02046 + 5,10-methylenetetrahydrofolate + NAD --> 5,10-methenyl-THF + NADH 0.3388606764375558 r_0732 methylenetetrahydrofolate dehydrogenase (NADP) 3.1493641930417993 prot_P07245 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) 0.0 r_0733 methylenetetrahydrofolate dehydrogenase (NADP) 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) 0.0 r_0734 methylisocitrate lyase 1.3673400673400673 prot_Q12031 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> pyruvate + succinate 0.0 -r_0735 mevalonate kinase (atp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + ATP --> (R)-5-phosphomevalonic acid + ADP + H+ 0.022347724063098005 +r_0735 mevalonate kinase (atp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + ATP --> (R)-5-phosphomevalonic acid + ADP + H+ 0.022347724064798527 r_0736 mevalonate kinase (ctp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + CTP --> (R)-5-phosphomevalonic acid + CDP + H+ 0.0 r_0737 mevalonate kinase (gtp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + GTP --> (R)-5-phosphomevalonic acid + GDP + H+ 0.0 r_0738 mevalonate kinase (UTP) 0.4723196881091618 prot_P07277 + (R)-mevalonate + UTP --> (R)-5-phosphomevalonic acid + H+ + UDP 0.0 -r_0739 mevalonate pyrophoshate decarboxylase 2.500907029478458 prot_P32377 + (R)-5-diphosphomevalonic acid + ATP --> ADP + carbon dioxide + isopentenyl diphosphate + phosphate 0.022347724063098005 +r_0739 mevalonate pyrophoshate decarboxylase 2.500907029478458 prot_P32377 + (R)-5-diphosphomevalonic acid + ATP --> ADP + carbon dioxide + isopentenyl diphosphate + phosphate 0.022347724064798527 r_0747_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide A (C24) --> GDP + H+ + mannosylinositol phosphorylceramide A (C24) 0.0 r_0747_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide A (C24) --> GDP + H+ + mannosylinositol phosphorylceramide A (C24) 0.0 r_0748_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide A (C26) --> GDP + H+ + mannosylinositol phosphorylceramide A (C26) 0.0 @@ -913,16 +913,16 @@ r_0755_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 pro r_0755_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide D (C24) --> GDP + H+ + mannosylinositol phosphorylceramide D (C24) 0.0 r_0756_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide D (C26) --> GDP + H+ + mannosylinositol phosphorylceramide D (C26) 0.0 r_0756_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide D (C26) --> GDP + H+ + mannosylinositol phosphorylceramide D (C26) 0.0 -r_0757_EXP_1 myo-inositol 1-phosphatase 0.03326388888888889 prot_Q05533 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.00082568341409782 +r_0757_EXP_1 myo-inositol 1-phosphatase 0.03326388888888889 prot_Q05533 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0008256834141765318 r_0757_EXP_2 myo-inositol 1-phosphatase 0.0340205223880597 prot_P38710 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0 -r_0758 myo-inositol-1-phosphate synthase 1.7257523148148148 prot_P11986 + D-glucose 6-phosphate --> 1D-myo-inositol 1-phosphate 0.00082568341409782 +r_0758 myo-inositol-1-phosphate synthase 1.7257523148148148 prot_P11986 + D-glucose 6-phosphate --> 1D-myo-inositol 1-phosphate 0.0008256834141766589 r_0759 N-acetyl-g-glutamyl-phosphate reductase 3.4224025974025976 prot_Q01217 + H+ + N-acetyl-L-gamma-glutamyl phosphate + NADPH --> 2-acetamido-5-oxopentanoate + NADP(+) + phosphate 0.031073733655750127 r_0760 N-acetylglucosamine-6-phosphate synthase 0.4886032977691562 prot_P43577 + acetyl-CoA + alpha-D-glucosamine 6-phosphate --> coenzyme A + H+ + N-acetyl-D-glucosamine 6-phosphate 0.0023610000000000003 r_0761_EXP_1 N-acteylglutamate synthase 82.8409090909091 prot_P40360 + acetyl-CoA + L-glutamate --> coenzyme A + H+ + N-acetyl-L-glutamate 0.0 r_0761_EXP_2 N-acteylglutamate synthase 0.6359516214779373 prot_Q04728 + acetyl-CoA + L-glutamate --> coenzyme A + H+ + N-acetyl-L-glutamate 0.0 r_0761_REV_EXP_1 N-acteylglutamate synthase (reversible) 23.365384615384617 prot_P40360 + coenzyme A + H+ + N-acetyl-L-glutamate --> acetyl-CoA + L-glutamate 0.0 r_0761_REV_EXP_2 N-acteylglutamate synthase (reversible) 0.6359516214779373 prot_Q04728 + coenzyme A + H+ + N-acetyl-L-glutamate --> acetyl-CoA + L-glutamate 0.0 -r_0762 N-formyl-L-kynurenine amidohydrolase 0.05174430641821946 prot_Q04066 + H2O + N-formyl-L-kynurenine --> formate + H+ + L-kynurenine 0.000651639811831107 +r_0762 N-formyl-L-kynurenine amidohydrolase 0.05174430641821946 prot_Q04066 + H2O + N-formyl-L-kynurenine --> formate + H+ + L-kynurenine 0.0006516398118312475 r_0763 N-formyltyrosine oxidase 70.69806925295306 prot_P21595 + 77.40588128458634 prot_P21623 + H+ + 2.0 N-formyl-L-tyrosine + NADPH --> N,N'-diformyldityrosine + NADP(+) 0.0 r_0764 NAD diphosphatase 4835.111111111111 prot_P53164 + H2O + NAD --> AMP + 2.0 H+ + NMN 0.0 r_0765_EXP_1 NAD kinase 18.47685185185185 prot_P32622 + ATP + NAD --> ADP + H+ + NADP(+) 0.0 @@ -935,17 +935,17 @@ r_0767_EXP_2 NAD nucleosidase nuclear 42.186868686868685 prot_P53688 + H2O + NAD r_0767_EXP_3 NAD nucleosidase nuclear 58.28484848484848 prot_P53685 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 r_0767_EXP_4 NAD nucleosidase nuclear 51.03434343434343 prot_P53687 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 r_0767_EXP_5 NAD nucleosidase nuclear 40.38282828282828 prot_P53686 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 -r_0768 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0006071199974023795 +r_0768 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0006071199974010172 r_0769 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0 r_0769_REV NAD synthase (reversible) 3.5019965277777776 prot_P38795 + AMP + diphosphate + H+ + L-glutamate + NAD --> ATP + deamido-NAD(+) + H2O + L-glutamine 0.0 r_0770_EXP_1 NADH dehydrogenase, cytosolic/mitochondrial 0.034255 prot_Q07500 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 0.20347470208140603 -r_0770_EXP_2 NADH dehydrogenase, cytosolic/mitochondrial 0.034874444444444444 prot_P40215 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 3.378130949705206 +r_0770_EXP_2 NADH dehydrogenase, cytosolic/mitochondrial 0.034874444444444444 prot_P40215 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 3.3248833485831866 r_0771_EXP_1 NADH kinase 0.9640096618357487 prot_P32622 + ATP + NADH --> ADP + H+ + NADPH 0.0 -r_0771_EXP_2 NADH kinase 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.00032700000447105637 +r_0771_EXP_2 NADH kinase 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0003270000044708343 r_0772_EXP_1 NADH kinase mitochondrial 0.9640096618357487 prot_P32622 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0772_EXP_2 NADH kinase mitochondrial 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0772_EXP_3 NADH kinase mitochondrial 0.7979123533471358 prot_Q06892 + ATP + NADH --> ADP + H+ + NADPH 0.0 -r_0773 NADH:ubiquinone oxidoreductase 0.03180555555555555 prot_P32340 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 4.678048412818931 +r_0773 NADH:ubiquinone oxidoreductase 0.03180555555555555 prot_P32340 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 4.722697531709967 r_0774 NAPRtase 62.59351652704193 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 1.20000004244503e-07 r_0775 NAPRtase 54.465555555555554 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 0.0 r_0781 nicotinamidase 1.8269736842105264 prot_P53184 + H2O + nicotinamide --> ammonium + nicotinate 1.20000004244503e-07 @@ -954,9 +954,9 @@ r_0783_EXP_1 nicotinamide-nucleotide adenylyltransferase 0.15292207792207793 pro r_0783_EXP_2 nicotinamide-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + NMN --> diphosphate + NAD 0.0 r_0784_EXP_1 nicotinamide-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + NMN --> diphosphate + NAD 0.0 r_0784_EXP_2 nicotinamide-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + NMN --> diphosphate + NAD 0.0 -r_0785_EXP_1 nicotinate-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0006071199974023795 +r_0785_EXP_1 nicotinate-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0006071199974010172 r_0785_EXP_2 nicotinate-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0 -r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.000606999997398135 +r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0006069999973967727 r_0787 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0 r_0788 nucleoside diphosphatase 0.25820037372430643 prot_P40009 + ADP + H2O --> AMP + H+ + phosphate 0.0 r_0789 nucleoside diphosphatase 0.19246758812814743 prot_P40009 + GDP + H2O --> GMP + H+ + phosphate 0.0 @@ -964,12 +964,12 @@ r_0790 nucleoside diphosphatase 0.24671061667353386 prot_P40009 + H2O + UDP --> r_0791 nucleoside diphosphatase 0.004121119814331302 prot_P32621 + H2O + UDP --> H+ + phosphate + UMP 0.0 r_0792 nucleoside diphosphatase 0.00661109270913842 prot_P40009 + CDP + H2O --> CMP + H+ + phosphate 0.0 r_0793 nucleoside diphosphatase 0.24979835905993603 prot_P40009 + H2O + IDP --> H+ + IMP + phosphate 0.0 -r_0795 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + CDP --> ADP + CTP 0.006460954116156428 +r_0795 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + CDP --> ADP + CTP 0.006460954213813954 r_0796 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dADP --> ADP + dATP 0.0 r_0797 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dCDP --> ADP + dCTP 0.0 r_0798 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dGDP --> ADP + dGTP 0.0 r_0799 nucleoside diphosphate kinase 0.3585421888053467 prot_P36010 + ATP + dTDP --> ADP + dTTP 0.0 -r_0800 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + GDP --> ADP + GTP 0.15459740621714804 +r_0800 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + GDP --> ADP + GTP 0.15459740621739643 r_0801 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + IDP --> ADP + ITP 0.0 r_0802 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dIDP --> ADP + dITP 0.0 r_0802_REV nucleoside diphosphate kinase (reversible) 0.3585421888053467 prot_P36010 + ADP + dITP --> ATP + dIDP 0.0 @@ -984,7 +984,7 @@ r_0807 nucleoside triphosphatase 0.00673132000048749 prot_P47119 + H2O + ITP --> r_0810 nucleoside-diphosphatase (GDP), Golgi 0.004121119814331302 prot_P32621 + GDP + H2O --> GMP + H+ + phosphate 0.0 r_0811 nucleoside-diphosphate kinase (ATP:UDP) 0.014855486327448944 prot_P36010 + ATP + UDP --> ADP + UTP 0.1546426239184487 r_0812 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + methanethiol + O-acetyl-L-homoserine --> acetate + H+ + L-methionine 0.0 -r_0813 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + hydrogen sulfide + O-acetyl-L-homoserine --> acetate + L-homocysteine 0.011924796613569637 +r_0813 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + hydrogen sulfide + O-acetyl-L-homoserine --> acetate + L-homocysteine 0.011924796613569787 r_0815_EXP_1 O-succinylhomoserine lyase (L-cysteine) 84.53345338034984 prot_Q12198 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 r_0815_EXP_2 O-succinylhomoserine lyase (L-cysteine) 0.170599173553719 prot_Q04533 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 r_0815_EXP_3 O-succinylhomoserine lyase (L-cysteine) 78.78148148148148 prot_P31373 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 @@ -994,49 +994,49 @@ r_0818 ornithine transacetylase 0.6359516214779373 prot_Q04728 + L-glutamate + N r_0819 ornithine transaminase 0.3585901027077497 prot_P07991 + 2-oxoglutarate + ornithine --> L-glutamate + L-glutamic 5-semialdehyde 0.011644113136055727 r_0820_EXP_1 orotate phosphoribosyltransferase 5.27008547008547 prot_P13298 + diphosphate + orotidine 5'-(dihydrogen phosphate) --> orotate + PRPP 0.0 r_0820_EXP_2 orotate phosphoribosyltransferase 5.301495726495727 prot_P30402 + diphosphate + orotidine 5'-(dihydrogen phosphate) --> orotate + PRPP 0.0 -r_0820_REV_EXP_1 orotate phosphoribosyltransferase (reversible) 0.0019386279318367604 prot_P13298 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.010726833614579979 +r_0820_REV_EXP_1 orotate phosphoribosyltransferase (reversible) 0.0019386279318367604 prot_P13298 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.010726833614579982 r_0820_REV_EXP_2 orotate phosphoribosyltransferase (reversible) 0.001950182355530403 prot_P30402 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.0 -r_0821 orotidine-5'-phosphate decarboxylase 0.014249512670565302 prot_P03962 + H+ + orotidine 5'-(dihydrogen phosphate) --> carbon dioxide + UMP 0.010726833614579979 -r_0831_EXP_1 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.04684031538764905 prot_P09624 + 0.043736418169126635 prot_P19262 + 0.011871821465312496 prot_P19955 + 0.09922757869641279 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 1.3454307817377134 -r_0831_EXP_2 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 0.07152726953060107 -r_0832_EXP_1 oxoglutarate dehydrogenase (lipoamide) 0.023116760828625234 prot_P09624 + 0.021584916966272898 prot_P19262 + 0.005859013867488444 prot_P19955 + 0.048971066598185245 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 1.4169580512683144 +r_0821 orotidine-5'-phosphate decarboxylase 0.014249512670565302 prot_P03962 + H+ + orotidine 5'-(dihydrogen phosphate) --> carbon dioxide + UMP 0.010726833614579982 +r_0831_EXP_1 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.04684031538764905 prot_P09624 + 0.043736418169126635 prot_P19262 + 0.011871821465312496 prot_P19955 + 0.09922757869641279 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 1.4203753767879987 +r_0831_EXP_2 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 0.0 +r_0832_EXP_1 oxoglutarate dehydrogenase (lipoamide) 0.023116760828625234 prot_P09624 + 0.021584916966272898 prot_P19262 + 0.005859013867488444 prot_P19955 + 0.048971066598185245 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 1.4203753767879987 r_0832_EXP_2 oxoglutarate dehydrogenase (lipoamide) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 0.0 -r_0841 pantetheine-phosphate adenylyltransferase 1.9636765345605238 prot_P53332 + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 0.011148385396473228 -r_0842 pantothenate kinase 5.359407756813417 prot_Q04430 + (R)-pantothenate + ATP --> (R)-4'-phosphopantothenic acid + ADP + H+ 1.900000061120133e-05 -r_0843 pantothenate synthase 0.07626262626262627 prot_P40459 + (R)-pantoate + ATP + beta-alanine --> (R)-pantothenate + AMP + diphosphate + H+ 1.900000061120133e-05 -r_0844 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + decanoyl-CoA + H2O --> coenzyme A + decanoate + H+ 0.002415660218418773 +r_0841 pantetheine-phosphate adenylyltransferase 1.9636765345605238 prot_P53332 + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 0.011148385396473356 +r_0842 pantothenate kinase 5.359407756813417 prot_Q04430 + (R)-pantothenate + ATP --> (R)-4'-phosphopantothenic acid + ADP + H+ 1.9000000611330134e-05 +r_0843 pantothenate synthase 0.07626262626262627 prot_P40459 + (R)-pantoate + ATP + beta-alanine --> (R)-pantothenate + AMP + diphosphate + H+ 1.9000000611330134e-05 +r_0844 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + decanoyl-CoA + H2O --> coenzyme A + decanoate + H+ 0.0024499794964130558 r_0845 peroxisomal acyl-CoA thioesterase 1.1039815728858178 prot_P41903 + H2O + lauroyl-CoA --> coenzyme A + H+ + laurate 0.00044172356996047285 -r_0847 peroxisomal acyl-CoA thioesterase 302.2522522522523 prot_P41903 + H2O + palmitoyl-CoA --> coenzyme A + H+ + palmitate 1.1847279353553024e-12 -r_0848 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + myristoyl-CoA --> coenzyme A + H+ + myristate 0.00025539365650321597 +r_0847 peroxisomal acyl-CoA thioesterase 302.2522522522523 prot_P41903 + H2O + palmitoyl-CoA --> coenzyme A + H+ + palmitate -5.504618137176787e-12 +r_0848 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + myristoyl-CoA --> coenzyme A + H+ + myristate 0.00025539366341234895 r_0849 peroxisomal acyl-CoA thioesterase 588.5964912280702 prot_P41903 + H2O + stearoyl-CoA --> coenzyme A + H+ + stearate 0.0 r_0850 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + octanoyl-CoA --> coenzyme A + H+ + octanoate 0.0 r_0851 phenylalanine transaminase 1.8801204819277106 prot_P53090 + 2-oxoglutarate + L-phenylalanine --> keto-phenylpyruvate + L-glutamate 0.0 -r_0851_REV phenylalanine transaminase (reversible) 0.550322030209992 prot_P53090 + keto-phenylpyruvate + L-glutamate --> 2-oxoglutarate + L-phenylalanine 0.0631041851469817 +r_0851_REV phenylalanine transaminase (reversible) 0.550322030209992 prot_P53090 + keto-phenylpyruvate + L-glutamate --> 2-oxoglutarate + L-phenylalanine 0.06310418514698156 r_0852 phenylalanyl-tRNA synthetase 0.06206467661691542 prot_P15624 + 0.05298599594619495 prot_P15625 + ATP + L-phenylalanine + tRNA(Phe) --> AMP + diphosphate + Phe-tRNA(Phe) 0.016679595802671702 r_0853 phenylalanyl-tRNA synthetase 0.025257508752533627 prot_P08425 + ATP + L-phenylalanine + tRNA(Phe) --> AMP + diphosphate + Phe-tRNA(Phe) 0.0 r_0854 phenylpyruvate decarboxylase 0.9914444444444445 prot_Q06408 + H+ + keto-phenylpyruvate --> carbon dioxide + phenylacetaldehyde 0.0 -r_0855 phopshoribosylaminoimidazole synthetase 3.4153968253968254 prot_P07244 + 5'-phosphoribosyl-N-formylglycineamidine + ATP --> 5'-phosphoribosyl-5-aminoimidazole + ADP + H+ + phosphate 0.010240426385259176 +r_0855 phopshoribosylaminoimidazole synthetase 3.4153968253968254 prot_P07244 + 5'-phosphoribosyl-N-formylglycineamidine + ATP --> 5'-phosphoribosyl-5-aminoimidazole + ADP + H+ + phosphate 0.01024042638550752 r_0882 phosphoacetylglucosamine mutase 0.4264366394591475 prot_P38628 + N-acetyl-D-glucosamine 6-phosphate --> N-acetyl-alpha-D-glucosamine 1-phosphate 0.0023610000000000003 r_0882_REV phosphoacetylglucosamine mutase (reversible) 0.4264366394591475 prot_P38628 + N-acetyl-alpha-D-glucosamine 1-phosphate --> N-acetyl-D-glucosamine 6-phosphate 0.0 -r_0883_EXP_1 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8892063492063492 prot_P22803 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.012044165779709898 +r_0883_EXP_1 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8892063492063492 prot_P22803 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.012044165779789976 r_0883_EXP_2 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8916666666666667 prot_P22217 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.0 r_0884 phosphoenolpyruvate carboxykinase 0.27322132616487455 prot_P10963 + ATP + oxaloacetate --> ADP + carbon dioxide + phosphoenolpyruvate 0.0 r_0885 phosphoethanolamine cytidyltransferase 8.904106280193236 prot_P33412 + CTP + H+ + O-phosphoethanolamine --> CDP-ethanolamine + diphosphate 0.0 -r_0886 phosphofructokinase 0.06875388870533351 prot_P16861 + 0.06661937879572642 prot_P16862 + ATP + D-fructose 6-phosphate --> ADP + D-fructose 1,6-bisphosphate + H+ 1.9011565964717327 +r_0886 phosphofructokinase 0.06875388870533351 prot_P16861 + 0.06661937879572642 prot_P16862 + ATP + D-fructose 6-phosphate --> ADP + D-fructose 1,6-bisphosphate + H+ 1.9045739219918443 r_0888_EXP_1 phosphoglucomutase 0.08151033591731266 prot_P37012 + D-glucose 6-phosphate --> D-glucose 1-phosphate 0.147954 r_0888_EXP_2 phosphoglucomutase 0.08154005167958657 prot_P33401 + D-glucose 6-phosphate --> D-glucose 1-phosphate 0.0 r_0888_REV_EXP_1 phosphoglucomutase (reversible) 0.08151033591731266 prot_P37012 + D-glucose 1-phosphate --> D-glucose 6-phosphate 0.0 r_0888_REV_EXP_2 phosphoglucomutase (reversible) 0.08154005167958657 prot_P33401 + D-glucose 1-phosphate --> D-glucose 6-phosphate 0.0 r_0889_EXP_1 phosphogluconate dehydrogenase 0.41150030525030523 prot_P53319 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.0 -r_0889_EXP_2 phosphogluconate dehydrogenase 0.40860042735042734 prot_P38720 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 6.34934813059651e-13 +r_0889_EXP_2 phosphogluconate dehydrogenase 0.40860042735042734 prot_P38720 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.0 r_0890 phosphoglucosamine mutase 0.4264366394591475 prot_P38628 + alpha-D-glucosamine 1-phosphate --> alpha-D-glucosamine 6-phosphate 0.0 r_0890_REV phosphoglucosamine mutase (reversible) 0.4264366394591475 prot_P38628 + alpha-D-glucosamine 6-phosphate --> alpha-D-glucosamine 1-phosphate 0.0 r_0891_EXP_1 phosphoglycerate dehydrogenase 0.0036935786435786434 prot_P40054 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.0 -r_0891_EXP_2 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.4028444709126094 -r_0892 phosphoglycerate kinase 0.02315487650870546 prot_P00560 + 1,3-bisphospho-D-glycerate + ADP --> 3-phosphonato-D-glycerate(3-) + ATP 3.668973485503852 +r_0891_EXP_2 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.40284447091191267 +r_0892 phosphoglycerate kinase 0.02315487650870546 prot_P00560 + 1,3-bisphospho-D-glycerate + ADP --> 3-phosphonato-D-glycerate(3-) + ATP 3.6361105318500258 r_0892_REV phosphoglycerate kinase (reversible) 0.02315487650870546 prot_P00560 + 3-phosphonato-D-glycerate(3-) + ATP --> 1,3-bisphospho-D-glycerate + ADP 0.0 r_0893_EXP_1 phosphoglycerate mutase 1.1738045797601886 prot_Q12040 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 0.0 -r_0893_EXP_2 phosphoglycerate mutase 0.013314525462962964 prot_P00950 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 3.2661290145912427 +r_0893_EXP_2 phosphoglycerate mutase 0.013314525462962964 prot_P00950 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 3.233266060938113 r_0893_REV_EXP_1 phosphoglycerate mutase (reversible) 2.640272344101795 prot_Q12040 + 2-phospho-D-glyceric acid --> 3-phosphonato-D-glycerate(3-) 0.0 r_0893_REV_EXP_2 phosphoglycerate mutase (reversible) 0.013314525462962964 prot_P00950 + 2-phospho-D-glyceric acid --> 3-phosphonato-D-glycerate(3-) 0.0 r_0902 phosphomannomutase 1.8347853535353533 prot_P07283 + D-mannose 1-phosphate --> D-mannose 6-phosphate 0.0 @@ -1044,33 +1044,33 @@ r_0902_REV phosphomannomutase (reversible) 0.40001070189485594 prot_P07283 + D-m r_0903_EXP_1 phosphomethylpyrimidine kinase 39.57945736434109 prot_Q08224 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 1.20000004244503e-07 r_0903_EXP_2 phosphomethylpyrimidine kinase 39.62144702842377 prot_Q08975 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 0.0 r_0903_EXP_3 phosphomethylpyrimidine kinase 695.1822835935426 prot_Q06490 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 0.0 -r_0904 phosphomevalonate kinase 4.122140522875817 prot_P24521 + (R)-5-phosphomevalonic acid + ATP --> (R)-5-diphosphomevalonic acid + ADP 0.022347724063098005 -r_0905 phosphopantothenate-cysteine ligase 4.010249042145594 prot_P40506 + (R)-4'-phosphopantothenic acid + CTP + L-cysteine --> CMP + diphosphate + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine 1.900000061120133e-05 -r_0906 phosphopantothenoylcysteine decarboxylase 5.98448275862069 prot_P36024 + 6.248850574712644 prot_P36076 + 7.054501915708812 prot_Q08438 + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine --> carbon dioxide + pantetheine 4'-phosphate 1.900000061120133e-05 +r_0904 phosphomevalonate kinase 4.122140522875817 prot_P24521 + (R)-5-phosphomevalonic acid + ATP --> (R)-5-diphosphomevalonic acid + ADP 0.022347724064798527 +r_0905 phosphopantothenate-cysteine ligase 4.010249042145594 prot_P40506 + (R)-4'-phosphopantothenic acid + CTP + L-cysteine --> CMP + diphosphate + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine 1.9000000611330134e-05 +r_0906 phosphopantothenoylcysteine decarboxylase 5.98448275862069 prot_P36024 + 6.248850574712644 prot_P36076 + 7.054501915708812 prot_Q08438 + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine --> carbon dioxide + pantetheine 4'-phosphate 1.9000000611330134e-05 r_0907_EXP_1 phosphopentomutase 0.08154005167958657 prot_P33401 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_EXP_2 phosphopentomutase 0.08151033591731266 prot_P37012 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_EXP_3 phosphopentomutase 0.10671021021021021 prot_Q03262 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_REV_EXP_1 phosphopentomutase (reversible) 0.08154005167958657 prot_P33401 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0 r_0907_REV_EXP_2 phosphopentomutase (reversible) 0.08151033591731266 prot_P37012 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0013291366958389087 r_0907_REV_EXP_3 phosphopentomutase (reversible) 0.10671021021021021 prot_Q03262 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0 -r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.17755272474518155 prot_P27616 + ATP + L-aspartate + phosphoribosyl-carboxy-aminoimidazole --> 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + 2.0 H+ + phosphate 0.010240306385254931 +r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.17755272474518155 prot_P27616 + ATP + L-aspartate + phosphoribosyl-carboxy-aminoimidazole --> 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + 2.0 H+ + phosphate 0.010240306385503276 r_0909 phosphoribosyl-AMP cyclohydrolase 0.00852140040022537 prot_P00815 + 1-(5-phosphoribosyl)-5'-AMP + H2O --> 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide 0.008356708763266002 r_0910 phosphoribosyl-ATP pyrophosphatase 6.601766492974471 prot_P00815 + 5-phosphoribosyl-ATP + H2O --> 1-(5-phosphoribosyl)-5'-AMP + diphosphate + H+ 0.008356708763266002 -r_0911 phosphoribosylaminoimidazole-carboxylase 0.2248881673881674 prot_P21264 + 5'-phosphoribosyl-5-aminoimidazole + carbon dioxide --> H+ + phosphoribosyl-carboxy-aminoimidazole 0.010240306385254931 +r_0911 phosphoribosylaminoimidazole-carboxylase 0.2248881673881674 prot_P21264 + 5'-phosphoribosyl-5-aminoimidazole + carbon dioxide --> H+ + phosphoribosyl-carboxy-aminoimidazole 0.010240306385503276 r_0912_EXP_1 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.10859173126615 prot_P54113 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.0 -r_0912_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.1079780361757106 prot_P38009 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.018597015148520933 +r_0912_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.1079780361757106 prot_P38009 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.018597015148769276 r_0912_REV_EXP_1 phosphoribosylaminoimidazolecarboxamide formyltransferase (reversible) 2.10859173126615 prot_P54113 + phosphoribosyl-formamido-carboxamide + THF --> 10-formyl-THF + AICAR 0.0 r_0912_REV_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase (reversible) 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide + THF --> 10-formyl-THF + AICAR 0.0 -r_0913 phosphoribosylanthranilate isomerase 0.09719806763285024 prot_P00912 + N-(5-phospho-beta-D-ribosyl)anthranilate --> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 0.0045086212576769275 -r_0914 phosphoribosylglycinamidine synthetase 3.4153968253968254 prot_P07244 + 5-phosphoribosylamine + ATP + L-glycine --> 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate 0.010240426385259176 -r_0915 phosphoribosylpyrophosphate amidotransferase 0.28336830535571544 prot_P04046 + H2O + L-glutamine + PRPP --> 5-phosphoribosylamine + diphosphate + L-glutamate 0.010240426385259176 -r_0916_EXP_1 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11565202927478377 prot_P38620 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.034439710018184466 +r_0913 phosphoribosylanthranilate isomerase 0.09719806763285024 prot_P00912 + N-(5-phospho-beta-D-ribosyl)anthranilate --> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 0.004508621257677068 +r_0914 phosphoribosylglycinamidine synthetase 3.4153968253968254 prot_P07244 + 5-phosphoribosylamine + ATP + L-glycine --> 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate 0.01024042638550752 +r_0915 phosphoribosylpyrophosphate amidotransferase 0.28336830535571544 prot_P04046 + H2O + L-glutamine + PRPP --> 5-phosphoribosylamine + diphosphate + L-glutamate 0.01024042638550752 +r_0916_EXP_1 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11565202927478377 prot_P38620 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.03443971001843159 r_0916_EXP_2 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11684630738522954 prot_P38689 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_3 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11882900864936793 prot_P38063 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_4 phosphoribosylpyrophosphate synthetase 0.11565202927478377 prot_P38620 + 0.17799401197604792 prot_Q12265 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_5 phosphoribosylpyrophosphate synthetase 0.11882900864936793 prot_P38063 + 0.17799401197604792 prot_Q12265 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 -r_0917 phosphoserine phosphatase (L-serine) 0.006309392061384094 prot_P42941 + 3-phospho-serine + H2O --> L-serine + phosphate 0.4028444709126094 -r_0918 phosphoserine transaminase 4.103165485515034 prot_P33330 + 3-phospho-hydroxypyruvate + L-glutamate --> 2-oxoglutarate + 3-phospho-serine 0.4028444709126094 +r_0917 phosphoserine phosphatase (L-serine) 0.006309392061384094 prot_P42941 + 3-phospho-serine + H2O --> L-serine + phosphate 0.40284447091191267 +r_0918 phosphoserine transaminase 4.103165485515034 prot_P33330 + 3-phospho-hydroxypyruvate + L-glutamate --> 2-oxoglutarate + 3-phospho-serine 0.40284447091191267 r_0919 phytoceramidase 13.387690165065315 prot_P38298 + lignoceric acid + phytosphingosine --> ceramide-2 (C24) + H2O 0.0 r_0920 phytoceramidase 107.0999354737445 prot_P21595 + cerotic acid + phytosphingosine --> ceramide-2 (C26) + H2O 0.0 r_0921 Phytosphingosine phosphate lyase 82.78535353535354 prot_Q05567 + phytosphingosine 1-phosphate --> 2-hydroxyhexadecanal + O-phosphoethanolamine 0.0 @@ -1079,8 +1079,8 @@ r_0929 polyamine oxidase 0.4117236467236467 prot_P50264 + H2O + N(1)-acetylsperm r_0935 porphobilinogen synthase 1.9935529153386848 prot_P05373 + 2.0 5-aminolevulinate --> H+ + 2.0 H2O + porphobilinogen 0.0 r_0936 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + N(1)-acetylspermine + oxygen --> 3-aminopropanal + hydrogen peroxide + N(1)-acetylspermidine 0.0 r_0937 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + oxygen + spermine --> 3-aminopropanal + hydrogen peroxide + spermidine 0.0013291366958389087 -r_0938 prephenate dehydratase 0.012934651669576752 prot_P32452 + H+ + prephenate --> carbon dioxide + H2O + keto-phenylpyruvate 0.0166795958026717 -r_0939 prephenate dehydrogenase (NADP) 0.537843261512463 prot_P20049 + NAD + prephenate --> 3-(4-hydroxyphenyl)pyruvate + carbon dioxide + NADH 0.02255454263921685 +r_0938 prephenate dehydratase 0.012934651669576752 prot_P32452 + H+ + prephenate --> carbon dioxide + H2O + keto-phenylpyruvate 0.016679595802671705 +r_0939 prephenate dehydrogenase (NADP) 0.537843261512463 prot_P20049 + NAD + prephenate --> 3-(4-hydroxyphenyl)pyruvate + carbon dioxide + NADH 0.012302566078787781 r_0940 proline oxidase (NAD) 0.44171641791044775 prot_P09368 + FAD + L-proline --> 1-pyrroline-5-carboxylate + FADH2 0.0 r_0941 prolyl-tRNA synthetase 3.83859126984127 prot_P38708 + ATP + L-proline + tRNA(Pro) --> AMP + diphosphate + Pro-tRNA(Pro) 0.0179821149401597 r_0942 protoporphyrinogen oxidase 34.59572043825653 prot_P40012 + 3.0 oxygen + 2.0 protoporphyrinogen --> 6.0 H2O + 2.0 protoporphyrin 0.0 @@ -1097,15 +1097,15 @@ r_0955 pyridoxine 5'-phosphate oxidase 10.677777777777777 prot_P38075 + oxygen + r_0956 pyridoxine oxidase 10.677777777777777 prot_P38075 + oxygen + pyridoxine --> hydrogen peroxide + pyridoxal 0.003696629304919432 r_0957 pyrroline-5-carboxylate reductase 0.0020925 prot_P32263 + 1-pyrroline-5-carboxylate + 2.0 H+ + NADPH --> L-proline + NADP(+) 0.0179821149401597 r_0958_EXP_1 pyruvate carboxylase 0.602625 prot_P32327 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.0 -r_0958_EXP_2 pyruvate carboxylase 0.6023101851851852 prot_P11154 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.25140525375141787 +r_0958_EXP_2 pyruvate carboxylase 0.6023101851851852 prot_P11154 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.26165723031249444 r_0959_EXP_1 pyruvate decarboxylase 0.27589605734767025 prot_P26263 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.0 -r_0959_EXP_2 pyruvate decarboxylase 0.08176022088979121 prot_P06169 + H+ + pyruvate --> acetaldehyde + carbon dioxide 2.613887674517869 +r_0959_EXP_2 pyruvate decarboxylase 0.08176022088979121 prot_P06169 + H+ + pyruvate --> acetaldehyde + carbon dioxide 1.3355054756878937 r_0959_EXP_3 pyruvate decarboxylase 0.27738351254480287 prot_P16467 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.0 r_0960_EXP_1 pyruvate decarboxylase (acetoin-forming) 0.27589605734767025 prot_P26263 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 r_0960_EXP_2 pyruvate decarboxylase (acetoin-forming) 0.11780651340996169 prot_P06169 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 r_0960_EXP_3 pyruvate decarboxylase (acetoin-forming) 0.27738351254480287 prot_P16467 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 -r_0961 pyruvate dehydrogenase 0.23664570803230708 prot_P09624 + 1.1352071189426114 prot_P12695 + 0.4061052415234663 prot_P16387 + 0.19875435304131667 prot_P16451 + 0.35099452655160257 prot_P32473 + coenzyme A + NAD + pyruvate --> acetyl-CoA + carbon dioxide + NADH 0.18291201317115655 -r_0962_EXP_1 pyruvate kinase 0.06530771072796934 prot_P00549 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 3.1787200948204686 +r_0961 pyruvate dehydrogenase 0.23664570803230708 prot_P09624 + 1.1352071189426114 prot_P12695 + 0.4061052415234663 prot_P16387 + 0.19875435304131667 prot_P16451 + 0.35099452655160257 prot_P32473 + coenzyme A + NAD + pyruvate --> acetyl-CoA + carbon dioxide + NADH 1.4852154906425028 +r_0962_EXP_1 pyruvate kinase 0.06530771072796934 prot_P00549 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 3.1663610942882 r_0962_EXP_2 pyruvate kinase 0.06608596743295019 prot_P52489 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 0.0 r_0963 quinone oxidoreductase 0.2834173315594083 prot_O13525 + 0.266570923780901 prot_P27680 + 0.191209663200305 prot_P41735 + 0.2544937516539746 prot_P49017 + 0.39274288726487816 prot_P53318 + 0.21981040253855474 prot_Q05779 + 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + NADH + oxygen --> 2-hexaprenyl-5-hydroxy-6-methoxy-3-methyl-1,4-benzoquinone + H2O + NAD 0.0 r_0964 reduced glutathione via ABC system 161.4141633681904 prot_P39109 + ATP + glutathione + H2O --> ADP + glutathione + H+ + phosphate 0.0 @@ -1142,11 +1142,11 @@ r_0979_EXP_1 ribonucleotide reductase 2.143863049095607 prot_P21524 + GDP + H+ + r_0979_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 r_0979_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 r_0979_EXP_4 ribonucleotide reductase 0.9936907838070629 prot_P09938 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 -r_0982 ribose-5-phosphate isomerase 0.5468480156600358 prot_Q12189 + D-ribulose 5-phosphate --> ribose-5-phosphate 0.0383473844399496 +r_0982 ribose-5-phosphate isomerase 0.5468480156600358 prot_Q12189 + D-ribulose 5-phosphate --> ribose-5-phosphate 0.03493005891975925 r_0982_REV ribose-5-phosphate isomerase (reversible) 0.817650462962963 prot_Q12189 + ribose-5-phosphate --> D-ribulose 5-phosphate 0.0 r_0983 ribosylnicotinamide kinase 4.5245098039215685 prot_P53915 + ATP + nicotinamide riboside --> ADP + H+ + NMN 0.0 r_0984 ribulose 5-phosphate 3-epimerase 0.06355115026921195 prot_P46969 + D-ribulose 5-phosphate --> D-xylulose 5-phosphate 0.0 -r_0984_REV ribulose 5-phosphate 3-epimerase (reversible) 0.06355115026921195 prot_P46969 + D-xylulose 5-phosphate --> D-ribulose 5-phosphate 0.038547384433534636 +r_0984_REV ribulose 5-phosphate 3-epimerase (reversible) 0.06355115026921195 prot_P46969 + D-xylulose 5-phosphate --> D-ribulose 5-phosphate 0.03513005891397922 r_0985 S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase 0.55303275478674 prot_O13525 + 0.5201603286342985 prot_P27680 + 0.37310776373372107 prot_P41735 + 0.49659412068703435 prot_P49017 + 0.7663599105669565 prot_P53318 + 0.42891643844723004 prot_Q05779 + 3-hexaprenyl-4,5-dihydroxybenzoic acid + S-adenosyl-L-methionine --> 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid + H+ + S-adenosyl-L-homocysteine 0.0 r_0986 S-adenosyl-methionine delta-24-sterol-c-methyltransferase 1096.7424242424245 prot_P25087 + S-adenosyl-L-methionine + zymosterol --> fecosterol + H+ + S-adenosyl-L-homocysteine 0.0003311237842365629 r_0987 S-formylglutathione hydralase 0.3307407407407407 prot_P40363 + H2O + S-formylglutathione --> formate + glutathione + H+ 0.0 @@ -1158,8 +1158,8 @@ r_0992 serine O-acetyltransferase 17.435821109618253 prot_P07347 + 62.4747269081 r_0993 serine palmitotransferase 11.220598845598845 prot_P25045 + 12.829184704184705 prot_P32368 + 11.383658008658008 prot_P40970 + 4.553571428571429 prot_P53224 + 4.483225108225108 prot_Q06144 + 1.727813852813853 prot_Q3E790 + H+ + L-serine + palmitoyl-CoA --> 3-ketosphinganine + carbon dioxide + coenzyme A 0.0 r_0995_EXP_1 seryl-tRNA synthetase 3.797008547008547 prot_P07284 + ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + Ser-tRNA(Ser) 0.027059237913871412 r_0995_EXP_2 seryl-tRNA synthetase 3.589031339031339 prot_P38705 + ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + Ser-tRNA(Ser) 0.0007133279844337922 -r_0996 shikimate dehydrogenase 0.12478934590117109 prot_P08566 + 3-dehydroshikimate + H+ + NADPH --> NADP(+) + shikimate 0.04370445988538707 -r_0997 shikimate kinase 0.1645527306967985 prot_P08566 + ATP + shikimate --> 3-phosphoshikimic acid + ADP + H+ 0.04370445988538707 +r_0996 shikimate dehydrogenase 0.12478934590117109 prot_P08566 + 3-dehydroshikimate + H+ + NADPH --> NADP(+) + shikimate 0.033452483324956706 +r_0997 shikimate kinase 0.1645527306967985 prot_P08566 + ATP + shikimate --> 3-phosphoshikimic acid + ADP + H+ 0.033452483324956706 r_0998 sirohydrochlorin dehydrogenase 147.7685185185185 prot_P15807 + NAD + precorrin-2 --> 2.0 H+ + NADH + sirohydrochlorin 0.0 r_0999 sirohydrochlorin ferrochetalase 147.7685185185185 prot_P15807 + iron(2+) + sirohydrochlorin --> 2.0 H+ + siroheme 0.0 r_1000 fumarate reductase (FMN) 0.9170995670995671 prot_P32614 + FMNH2 + fumarate --> FMN + H+ + succinate 0.0 @@ -1180,23 +1180,23 @@ r_1008_REV spontaneous cis-aconitate(3-) to trans-aconitate (reversible) 1.13290 r_1009 spontaneous cis-aconitate(3-) to trans-aconitate 1.1329040404040405 prot_standard + cis-aconitate --> trans-aconitate 0.0 r_1009_REV spontaneous cis-aconitate(3-) to trans-aconitate (reversible) 1.1329040404040405 prot_standard + trans-aconitate --> cis-aconitate 0.0 r_1010 squalene epoxidase (NAD) 201.483918128655 prot_P32476 + H+ + NADH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NAD 0.0 -r_1011 squalene epoxidase (NADP) 161.16753104520652 prot_P32476 + H+ + NADPH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NADP(+) 0.003724620677183001 -r_1012 squalene synthase 8.707070707070708 prot_P29704 + 2.0 farnesyl diphosphate + H+ + NADPH --> 2.0 diphosphate + NADP(+) + squalene 0.003724620677183001 +r_1011 squalene epoxidase (NADP) 161.16753104520652 prot_P32476 + H+ + NADPH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NADP(+) 0.003724620677466421 +r_1012 squalene synthase 8.707070707070708 prot_P29704 + 2.0 farnesyl diphosphate + H+ + NADPH --> 2.0 diphosphate + NADP(+) + squalene 0.003724620677466421 r_1021_EXP_1 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07412606837606837 prot_P47052 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.0 r_1021_EXP_2 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07503098290598291 prot_Q00711 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.0 -r_1021_EXP_3 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.07412606837606837 prot_P47052 + 0.019905982905982906 prot_Q06236 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 1.4276848848828945 +r_1021_EXP_3 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.07412606837606837 prot_P47052 + 0.019905982905982906 prot_Q06236 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 1.4311022104025788 r_1021_REV_EXP_1 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.022498888888888888 prot_P37298 + 0.07709111111111111 prot_P47052 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 r_1021_REV_EXP_2 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.022498888888888888 prot_P37298 + 0.07803222222222223 prot_Q00711 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 r_1021_REV_EXP_3 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.07709111111111111 prot_P47052 + 0.020702222222222223 prot_Q06236 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 -r_1022 succinate-CoA ligase (ADP-forming) 0.06481619679380873 prot_P53312 + 0.048413488114980655 prot_P53598 + ADP + phosphate + succinyl-CoA --> ATP + coenzyme A + succinate 0.0 +r_1022 succinate-CoA ligase (ADP-forming) 0.06481619679380873 prot_P53312 + 0.048413488114980655 prot_P53598 + ADP + phosphate + succinyl-CoA --> ATP + coenzyme A + succinate 1.3021212577778893 r_1023 succinate-semialdehyde dehydrogenase (NADP) 0.6660398230088496 prot_P38067 + H2O + NADP(+) + succinic semialdehyde --> 2.0 H+ + NADPH + succinate 0.0 r_1024 sucrose hydrolyzing enzyme 0.004910835762876579 prot_P00724 + H2O + sucrose --> D-fructose + D-glucose 0.0 -r_1025 sulfate adenylyltransferase 0.6571607468123861 prot_P08536 + ATP + H+ + sulphate --> 5'-adenylyl sulfate + diphosphate 0.012044165779709898 +r_1025 sulfate adenylyltransferase 0.6571607468123861 prot_P08536 + ATP + H+ + sulphate --> 5'-adenylyl sulfate + diphosphate 0.012044165779789976 r_1026 sulfate adenylyltransferase (ADP) 0.10559317129629629 prot_P16550 + 5'-adenylyl sulfate + phosphate --> ADP + H+ + sulphate 0.0 -r_1027 sulfite reductase (NADPH2) 0.4089351851851852 prot_P39692 + 0.574141737891738 prot_P47169 + 4.0 H+ + 3.0 NADPH + sulphite --> 3.0 H2O + hydrogen sulfide + 3.0 NADP(+) 0.012044165779709898 +r_1027 sulfite reductase (NADPH2) 0.4089351851851852 prot_P39692 + 0.574141737891738 prot_P47169 + 4.0 H+ + 3.0 NADPH + sulphite --> 3.0 H2O + hydrogen sulfide + 3.0 NADP(+) 0.012044165779789976 r_1028 taurcholate via ABC system 571.7858889359086 prot_P32386 + ATP + H2O + taurocholate --> ADP + H+ + phosphate + taurocholate 0.0 r_1029 taurine dioxygenase 0.6971220085126848 prot_Q12358 + 2-oxoglutarate + oxygen + taurine --> aminoacetaldehyde + carbon dioxide + H+ + succinate + sulphite 0.0 -r_1030 tetrahydrofolate aminomethyltransferase 0.12487609595740357 prot_P09624 + 0.0434511474046933 prot_P39726 + 0.10281642494222884 prot_P48015 + 0.2646212564047546 prot_P49095 + 5,10-methenyl-THF + H2O --> 5-formyltetrahydrofolic acid + H+ 0.2848213125470931 +r_1030 tetrahydrofolate aminomethyltransferase 0.12487609595740357 prot_P09624 + 0.0434511474046933 prot_P39726 + 0.10281642494222884 prot_P48015 + 0.2646212564047546 prot_P49095 + 5,10-methenyl-THF + H2O --> 5-formyltetrahydrofolic acid + H+ 0.0 r_1031_EXP_1 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) 6.686527777777778 prot_P36001 + ATP + L-glutamate + THF --> 5,6,7,8-tetrahydrofolyl-L-glutamic acid + ADP + H+ + phosphate 0.0 r_1031_EXP_2 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) 8.632083333333334 prot_Q08645 + ATP + L-glutamate + THF --> 5,6,7,8-tetrahydrofolyl-L-glutamic acid + ADP + H+ + phosphate 0.0 r_1031_REV_EXP_1 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) (reversible) 6.686527777777778 prot_P36001 + 5,6,7,8-tetrahydrofolyl-L-glutamic acid + ADP + H+ + phosphate --> ATP + L-glutamate + THF 0.0 @@ -1210,33 +1210,33 @@ r_1037_EXP_1 thioredoxin 0.16380116959064328 prot_P22803 + 0.3526315789473684 pr r_1037_EXP_2 thioredoxin 0.1642543859649123 prot_P22217 + 0.3526315789473684 prot_P40553 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_1038_EXP_1 thioredoxin reductase (NADPH) 0.09346012679346014 prot_P22803 + 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1038_EXP_2 thioredoxin reductase (NADPH) 0.09371871871871873 prot_P22217 + 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 -r_1038_EXP_3 thioredoxin reductase (NADPH) 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.02791828966292147 +r_1038_EXP_3 thioredoxin reductase (NADPH) 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.027865998936570522 r_1039_EXP_1 thioredoxin reductase (NADPH) 0.12038705372038706 prot_P25372 + 0.3093677010343677 prot_P38816 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1039_EXP_2 thioredoxin reductase (NADPH) 0.004454320987654321 prot_P25372 + 0.016494135802469136 prot_P41921 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1040 threonine aldolase 0.2765826873385013 prot_P37303 + L-threonine --> acetaldehyde + L-glycine 0.0 -r_1041 threonine synthase 0.003912990196078431 prot_P16120 + H2O + O-phospho-L-homoserine --> L-threonine + phosphate 0.02387172382427442 +r_1041 threonine synthase 0.003912990196078431 prot_P16120 + H2O + O-phospho-L-homoserine --> L-threonine + phosphate 0.023871723824274306 r_1042 threonyl-tRNA synthetase 7.242059017723929 prot_P04801 + ATP + L-threonine + tRNA(Thr) --> AMP + diphosphate + Thr-tRNA(Thr) 0.023517302829840103 r_1043 threonyl-tRNA synthetase 4.525769745649264 prot_P07236 + ATP + L-threonine + tRNA(Thr) --> AMP + diphosphate + Thr-tRNA(Thr) 0.0 r_1045 thymidylate synthase 0.20281828703703703 prot_P06785 + 5,10-methylenetetrahydrofolate + dUMP --> dihydrofolic acid + dTMP 0.00035999999381601804 r_1046 trans-aconitate 3-methyltransferase 147.17240726195595 prot_P32643 + S-adenosyl-L-methionine + trans-aconitate --> (2E)-3-(methoxycarbonyl)pent-2-enedioic acid + S-adenosyl-L-homocysteine 0.0 r_1047 trans-pentaprenyltranstransferase 1.43565817535086 prot_P18900 + isopentenyl diphosphate + pentaprenyl diphosphate --> diphosphate + hexaprenyl diphosphate 0.0 r_1048_EXP_1 transaldolase 0.796025641025641 prot_P53228 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.0 -r_1048_EXP_2 transaldolase 0.13717037037037036 prot_P15019 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.0025785377259262207 +r_1048_EXP_2 transaldolase 0.13717037037037036 prot_P15019 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.0 r_1048_REV_EXP_1 transaldolase (reversible) 0.4518922852983988 prot_P53228 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 -r_1048_REV_EXP_2 transaldolase (reversible) 0.13717037037037036 prot_P15019 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 +r_1048_REV_EXP_2 transaldolase (reversible) 0.13717037037037036 prot_P15019 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.000838787794511256 r_1049_EXP_1 transketolase 1 0.30204911433172305 prot_P33315 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 -r_1049_EXP_2 transketolase 1 0.2971256038647343 prot_P23254 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0025785377259262207 +r_1049_EXP_2 transketolase 1 0.2971256038647343 prot_P23254 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 r_1049_REV_EXP_1 transketolase 1 (reversible) 0.30204911433172305 prot_P33315 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0 -r_1049_REV_EXP_2 transketolase 1 (reversible) 0.2971256038647343 prot_P23254 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0 +r_1049_REV_EXP_2 transketolase 1 (reversible) 0.2971256038647343 prot_P23254 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.000838787794511256 r_1050_EXP_1 transketolase 2 0.30204911433172305 prot_P33315 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.0 r_1050_EXP_2 transketolase 2 0.2971256038647343 prot_P23254 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.0 r_1050_REV_EXP_1 transketolase 2 (reversible) 0.30204911433172305 prot_P33315 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.0 -r_1050_REV_EXP_2 transketolase 2 (reversible) 0.2971256038647343 prot_P23254 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.04112592215946085 +r_1050_REV_EXP_2 transketolase 2 (reversible) 0.2971256038647343 prot_P23254 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.03429127111946796 r_1051_EXP_1 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5532575757575757 prot_P38427 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.0 r_1051_EXP_2 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5004419191919192 prot_P38426 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.013655 -r_1054 triose-phosphate isomerase 0.0008592271925605259 prot_P00942 + dihydroxyacetone phosphate --> glyceraldehyde 3-phosphate 1.8044341899338914 +r_1054 triose-phosphate isomerase 0.0008592271925605259 prot_P00942 + dihydroxyacetone phosphate --> glyceraldehyde 3-phosphate 1.7613192597199716 r_1054_REV triose-phosphate isomerase (reversible) 0.0008592271925605259 prot_P00942 + glyceraldehyde 3-phosphate --> dihydroxyacetone phosphate 0.0 -r_1055 tryptophan synthase (indoleglycerol phosphate) 0.43168564547057753 prot_P00931 + 1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> glyceraldehyde 3-phosphate + H2O + L-tryptophan 0.0045086212576769275 +r_1055 tryptophan synthase (indoleglycerol phosphate) 0.43168564547057753 prot_P00931 + 1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> glyceraldehyde 3-phosphate + H2O + L-tryptophan 0.004508621257677068 r_1056 tryptophan transaminase 1.2484 prot_P53090 + 2-oxoglutarate + L-tryptophan --> indole-3-pyruvate + L-glutamate 0.0 r_1057 tryptophanyl-tRNA synthetase 0.5595238095238095 prot_Q12109 + ATP + L-tryptophan + tRNA(Trp) --> AMP + diphosphate + Trp-tRNA(Trp) 0.0038569814458458205 r_1058 tryptophanyl-tRNA synthetase 0.4876984126984127 prot_P04803 + ATP + L-tryptophan + tRNA(Trp) --> AMP + diphosphate + Trp-tRNA(Trp) 0.0 @@ -1252,7 +1252,7 @@ r_1070 UDPglucose 4-epimerase 0.532373366013072 prot_P04397 + UDP-D-glucose --> r_1070_REV UDPglucose 4-epimerase (reversible) 0.532373366013072 prot_P04397 + UDP-D-galactose --> UDP-D-glucose 0.0 r_1071 UDPglucose--hexose-1-phosphate uridylyltransferase 0.3270447530864197 prot_P08431 + alpha-D-galactose 1-phosphate + UDP-D-glucose --> D-glucose 1-phosphate + UDP-D-galactose 0.0 r_1071_REV UDPglucose--hexose-1-phosphate uridylyltransferase (reversible) 0.3270447530864197 prot_P08431 + D-glucose 1-phosphate + UDP-D-galactose --> alpha-D-galactose 1-phosphate + UDP-D-glucose 0.0 -r_1072 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.0049276239236641 +r_1072 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.004927623923664103 r_1073 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.0 r_1074 uracil phosphoribosyltransferase 1.1199453551912568 prot_P18562 + PRPP + uracil --> diphosphate + UMP 0.0 r_1075 urea carboxylase 0.26596036263967954 prot_P32528 + ATP + bicarbonate + urea --> ADP + H+ + phosphate + urea-1-carboxylic acid 0.0 @@ -1274,10 +1274,10 @@ r_1085_EXP_1 V-ATPase, Golgi 0.0066673789173789175 prot_P0C5R9 + 0.1233952991452 r_1085_EXP_2 V-ATPase, Golgi 0.04113176638176638 prot_P16140 + 0.08449928774928775 prot_P17255 + 0.018853988603988604 prot_P22203 + 0.016094017094017095 prot_P23968 + 0.011646011396011397 prot_P25515 + 0.03147364672364673 prot_P31412 + 0.02834116809116809 prot_P32366 + 0.020793447293447294 prot_P32610 + 0.012134615384615384 prot_P32842 + 0.07240811965811966 prot_P37296 + 0.009587606837606838 prot_P39111 + 0.03875783475783476 prot_P41807 + 0.009054843304843305 prot_P48836 + 0.021138176638176638 prot_P53262 + 0.005969373219373219 prot_Q3E7B6 + ATP + H+ + H2O --> ADP + 2.0 H+ + phosphate 0.0 r_1086_EXP_1 V-ATPase, vacuole 0.0066673789173789175 prot_P0C5R9 + 0.12339529914529915 prot_P16140 + 0.2534978632478633 prot_P17255 + 0.05656196581196581 prot_P22203 + 0.016094017094017095 prot_P23968 + 0.09316809116809117 prot_P25515 + 0.03147364672364673 prot_P31412 + 0.02834116809116809 prot_P32366 + 0.06804059829059829 prot_P32563 + 0.020793447293447294 prot_P32610 + 0.012134615384615384 prot_P32842 + 0.009587606837606838 prot_P39111 + 0.03875783475783476 prot_P41807 + 0.027164529914529913 prot_P48836 + 0.021138176638176638 prot_P53262 + 0.005969373219373219 prot_Q3E7B6 + ATP + H+ + H2O --> ADP + 2.0 H+ + phosphate 0.0 r_1086_EXP_2 V-ATPase, vacuole 0.04113176638176638 prot_P16140 + 0.08449928774928775 prot_P17255 + 0.018853988603988604 prot_P22203 + 0.016094017094017095 prot_P23968 + 0.011646011396011397 prot_P25515 + 0.03147364672364673 prot_P31412 + 0.02834116809116809 prot_P32366 + 0.06804059829059829 prot_P32563 + 0.020793447293447294 prot_P32610 + 0.012134615384615384 prot_P32842 + 0.009587606837606838 prot_P39111 + 0.03875783475783476 prot_P41807 + 0.009054843304843305 prot_P48836 + 0.021138176638176638 prot_P53262 + 0.005969373219373219 prot_Q3E7B6 + ATP + H+ + H2O --> ADP + 2.0 H+ + phosphate 0.0 -r_1087 valine transaminase 0.009354773462783171 prot_P47176 + 2-oxoglutarate + L-valine --> 3-methyl-2-oxobutanoate + L-glutamate 0.0041453650674776465 +r_1087 valine transaminase 0.009354773462783171 prot_P47176 + 2-oxoglutarate + L-valine --> 3-methyl-2-oxobutanoate + L-glutamate 0.0041453650681246845 r_1087_REV valine transaminase (reversible) 0.010755813953488373 prot_P47176 + 3-methyl-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-valine 0.0 r_1088 valine transaminase, mitochondiral 0.009797734627831714 prot_P38891 + 2-oxoglutarate + L-valine --> 3-methyl-2-oxobutanoate + L-glutamate 0.0 -r_1088_REV valine transaminase, mitochondiral (reversible) 0.011265116279069768 prot_P38891 + 3-methyl-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-valine 0.03560582004496365 +r_1088_REV valine transaminase, mitochondiral (reversible) 0.011265116279069768 prot_P38891 + 3-methyl-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-valine 0.035605820045610685 r_1089 valyl-tRNA synthetase 0.6987222222222222 prot_P07806 + ATP + L-valine + tRNA(Val) --> AMP + diphosphate + Val-tRNA(Val) 0.031460454977486 r_1090 valyl-tRNA synthetase 0.6987222222222222 prot_P07806 + ATP + L-valine + tRNA(Val) --> AMP + diphosphate + Val-tRNA(Val) 0.0 r_1091 xanthine phosphoribosyltransferase 1.5042841315863547 prot_P47165 + 9H-xanthine + PRPP --> diphosphate + xanthosine-5-phosphate 0.0 @@ -1299,8 +1299,8 @@ r_1096_REV_EXP_2 (R)-mevalonate transport (reversible) 182.48664015357193 prot_P r_1097 (R,R)-butanediol transport (R,R)-2,3-butanediol --> (R,R)-2,3-butanediol 0.0 r_1097_REV (R,R)-butanediol transport (reversible) (R,R)-2,3-butanediol --> (R,R)-2,3-butanediol 0.0 r_1098 2-methylbutyl transport 2-methylbutyl acetate --> 2-methylbutyl acetate 0.0 -r_1099_EXP_1 2-oxoadipate and 2-oxoglutarate transport 0.3902368014935992 prot_Q99297 + 2-oxoadipic acid + 2-oxoglutarate --> 2-oxoadipic acid + 2-oxoglutarate 0.021894005155858633 -r_1099_EXP_2 2-oxoadipate and 2-oxoglutarate transport 2.6118993789038507 prot_Q03028 + 2-oxoadipic acid + 2-oxoglutarate --> 2-oxoadipic acid + 2-oxoglutarate 0.011045958849795368 +r_1099_EXP_1 2-oxoadipate and 2-oxoglutarate transport 0.3902368014935992 prot_Q99297 + 2-oxoadipic acid + 2-oxoglutarate --> 2-oxoadipic acid + 2-oxoglutarate 0.032939964005654 +r_1099_EXP_2 2-oxoadipate and 2-oxoglutarate transport 2.6118993789038507 prot_Q03028 + 2-oxoadipic acid + 2-oxoglutarate --> 2-oxoadipic acid + 2-oxoglutarate 0.0 r_1099_REV_EXP_1 2-oxoadipate and 2-oxoglutarate transport (reversible) 0.3902368014935992 prot_Q99297 + 2-oxoadipic acid + 2-oxoglutarate --> 2-oxoadipic acid + 2-oxoglutarate 0.0 r_1099_REV_EXP_2 2-oxoadipate and 2-oxoglutarate transport (reversible) 2.6118993789038507 prot_Q03028 + 2-oxoadipic acid + 2-oxoglutarate --> 2-oxoadipic acid + 2-oxoglutarate 0.0 r_1100 3-hexaprenyl-4,5-dihydroxybenzoate transport 3-hexaprenyl-4,5-dihydroxybenzoic acid --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 @@ -1319,17 +1319,17 @@ r_1108_EXP_2 adenine transport 96.43325000488205 prot_P40039 + adenine + H+ --> r_1108_EXP_3 adenine transport 170.37838815188596 prot_Q12119 + adenine + H+ --> adenine + H+ 0.0 r_1109 adenosine transport 38.061322453849215 prot_P31381 + adenosine + H+ --> adenosine + H+ 0.0 r_1110_EXP_1 ADP/ATP transporter 0.06555300613384876 prot_P18239 + ADP + ATP --> ADP + ATP 0.0 -r_1110_EXP_2 ADP/ATP transporter 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 11.28777899117864 +r_1110_EXP_2 ADP/ATP transporter 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 12.967764681605324 r_1110_EXP_3 ADP/ATP transporter 0.045422922213833025 prot_P04710 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_1 ADP/ATP transporter (reversible) 0.06555300613384876 prot_P18239 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_2 ADP/ATP transporter (reversible) 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_3 ADP/ATP transporter (reversible) 0.045422922213833025 prot_P04710 + ADP + ATP --> ADP + ATP 0.0 r_1111 ADP/ATP transporter 1.0879458482506026 prot_Q06497 + ADP + ATP + H+ --> ADP + ATP + H+ 0.0 -r_1112 AKG transporter, mitochonrial 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 1.5141947047813955 +r_1112 AKG transporter, mitochonrial 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 1.4544637885593625 r_1112_REV AKG transporter, mitochonrial (reversible) 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 0.0 r_1113 allantoate uniport 1.2976708311906466 prot_P15365 + allantoate --> allantoate 0.0 r_1114 allantoin uniport 10.243314336688835 prot_Q04895 + allantoin --> allantoin 0.0 -r_1115_EXP_1 ammonia transport 0.565835007774522 prot_Q12359 + ammonium --> ammonium 0.9730850971666676 +r_1115_EXP_1 ammonia transport 0.565835007774522 prot_Q12359 + ammonium --> ammonium 0.9730850971669617 r_1115_EXP_2 ammonia transport 1.0213597006592061 prot_P40260 + ammonium --> ammonium 0.0 r_1115_EXP_3 ammonia transport 1.006265993411724 prot_P41948 + ammonium --> ammonium 0.0 r_1115_EXP_4 ammonia transport 1.0117117879117519 prot_P53390 + ammonium --> ammonium 0.0 @@ -1340,7 +1340,7 @@ r_1115_REV_EXP_4 ammonia transport (reversible) 1.3558080808080808 prot_P53390 + r_1116 AMP/ATP transporter 0.6269423034333512 prot_Q06497 + AMP + ATP + H+ --> AMP + ATP + H+ 0.0 r_1118 aspartate-glutamate transporter 3.465624071522008 prot_Q12482 + L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 r_1119 biotin uptake 12.492477484389962 prot_P53241 + biotin + H+ --> biotin + H+ 0.0 -r_1120 carnithine-acetylcarnithine carrier 1.094665810308139 prot_Q12289 + (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.007202150381957033 +r_1120 carnithine-acetylcarnithine carrier 1.094665810308139 prot_Q12289 + (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.007019930692418554 r_1121 ceramide-2' (sphinganine:n-C24:0OH) transport ceramide-2' (C24) --> ceramide-2' (C24) 0.0 r_1121_REV ceramide-2' (sphinganine:n-C24:0OH) transport (reversible) ceramide-2' (C24) --> ceramide-2' (C24) 0.0 r_1122 ceramide-2' (sphinganine:n-C26:0OH) transport ceramide-2' (C26) --> ceramide-2' (C26) 0.0 @@ -1356,7 +1356,7 @@ r_1127 citrate transport 0.4084348057672835 prot_P38152 + citrate + phosphoenolp r_1127_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.03127094379016974 r_1128 citrate transport 0.3417805406736961 prot_P38152 + citrate + isocitrate --> citrate + isocitrate 0.0 r_1128_REV citrate transport (reversible) 0.3417805406736961 prot_P38152 + citrate + isocitrate --> citrate + isocitrate 0.0 -r_1129 coenzyme A transport 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.033477109458960166 +r_1129 coenzyme A transport 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.033477109460660584 r_1130 CTP transport 0.2701553629071786 prot_P38127 + CMP + CTP + H+ --> CMP + CTP + H+ 0.0 r_1131 CTP/CMP antiport 0.2701553629071786 prot_P38127 + CMP + CTP + 2.0 H+ --> CMP + CTP + 2.0 H+ 0.0010292683075824678 r_1132 cytidine transport 19.950758151174124 prot_P31381 + cytidine + H+ --> cytidine + H+ 0.0 @@ -1385,9 +1385,9 @@ r_1135_EXP_3 D-galactose transport 7.895711187219881 prot_P13181 + D-galactose + r_1135_EXP_4 D-galactose transport 9.049001302171312 prot_P42833 + D-galactose + H+ --> D-galactose + H+ 0.0 r_1135_EXP_5 D-galactose transport 0.8760873219329858 prot_P54862 + D-galactose + H+ --> D-galactose + H+ 0.0 r_1136 D-lactate transport 1398.5378967792055 prot_P36035 + (R)-lactate + H+ --> (R)-lactate + H+ 0.0 -r_1137 D-lactate transport (R)-lactate + H+ --> (R)-lactate + H+ 0.30951600402324314 +r_1137 D-lactate transport (R)-lactate + H+ --> (R)-lactate + H+ 1.6118194814939426 r_1138 D-lactate/pyruvate antiport (R)-lactate + pyruvate --> (R)-lactate + pyruvate 0.0 -r_1138_REV D-lactate/pyruvate antiport (reversible) (R)-lactate + pyruvate --> (R)-lactate + pyruvate 0.30951600402324314 +r_1138_REV D-lactate/pyruvate antiport (reversible) (R)-lactate + pyruvate --> (R)-lactate + pyruvate 1.6034555408578242 r_1139_EXP_1 D-mannose transport 21.752276959457756 prot_P54854 + D-mannose + H+ --> D-mannose + H+ 0.0 r_1139_EXP_10 D-mannose transport 5.737789186505133 prot_P40885 + D-mannose + H+ --> D-mannose + H+ 0.0 r_1139_EXP_11 D-mannose transport 24.62776935429521 prot_P47185 + D-mannose + H+ --> D-mannose + H+ 0.0 @@ -1467,12 +1467,12 @@ r_1173_EXP_3 glycine transport 12.596301854889402 prot_P38967 + H+ + L-glycine - r_1173_EXP_4 glycine transport 14.445193920799005 prot_P15380 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_EXP_5 glycine transport 7.968919773312661 prot_P53388 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_1 glycine transport (reversible) 25.955237884466197 prot_P25376 + H+ + L-glycine --> H+ + L-glycine 0.0 -r_1173_REV_EXP_2 glycine transport (reversible) 4.0449974975144505 prot_P19145 + H+ + L-glycine --> H+ + L-glycine 0.32287972421607625 +r_1173_REV_EXP_2 glycine transport (reversible) 4.0449974975144505 prot_P19145 + H+ + L-glycine --> H+ + L-glycine 0.32287972421523614 r_1173_REV_EXP_3 glycine transport (reversible) 12.596301854889402 prot_P38967 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_4 glycine transport (reversible) 14.445193920799005 prot_P15380 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_5 glycine transport (reversible) 9.41498101418254 prot_P53388 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1174 glycogen vacuolar 'transport' via autophagy glycogen --> glycogen 0.0 -r_1175 GTP/GDP translocase 0.5104257838599212 prot_P38988 + GDP + GTP + H+ --> GDP + GTP + H+ 0.07048987427237073 +r_1175 GTP/GDP translocase 0.5104257838599212 prot_P38988 + GDP + GTP + H+ --> GDP + GTP + H+ 0.07048987427237079 r_1176_EXP_1 guanine transport 1.98390967747123 prot_P17064 + guanine + H+ --> guanine + H+ 0.0 r_1176_EXP_2 guanine transport 26.93240415537185 prot_P40039 + guanine + H+ --> guanine + H+ 0.0 r_1176_EXP_3 guanine transport 75.93503728388835 prot_Q12119 + guanine + H+ --> guanine + H+ 0.0 @@ -1516,7 +1516,7 @@ r_1192_EXP_5 L-cystine transport 3.8637388807060162 prot_P48813 + H+ + L-cystein r_1192_EXP_6 L-cystine transport 2.0808020354818835 prot_P19145 + H+ + L-cysteine --> H+ + L-cysteine 0.0 r_1192_EXP_7 L-cystine transport 4.954940745719529 prot_P38967 + H+ + L-cysteine --> H+ + L-cysteine 0.0 r_1193 L-cystine transport 7.973877475373074 prot_P17261 + H+ + L-cystine --> H+ + L-cystine 0.0 -r_1194 L-glutamate transport 1.8810464305164725 prot_Q12482 + L-glutamate --> L-glutamate 0.09775328735646391 +r_1194 L-glutamate transport 1.8810464305164725 prot_Q12482 + L-glutamate --> L-glutamate 0.09775328735711095 r_1195 L-glutamate transport 51.467278676926874 prot_P40074 + H+ + L-glutamate --> H+ + L-glutamate 0.0 r_1196_EXP_1 L-glutamate transport 7.883394470362304 prot_P25376 + H+ + L-glutamate --> H+ + L-glutamate 0.0 r_1196_EXP_2 L-glutamate transport 92.56119945738607 prot_P43548 + H+ + L-glutamate --> H+ + L-glutamate 0.0 @@ -1637,7 +1637,7 @@ r_1241 pantothenate transport 34.938176452130854 prot_P25621 + (R)-pantothenate r_1242 pentaprenyl diphosphate transport pentaprenyl diphosphate --> pentaprenyl diphosphate 0.0 r_1242_REV pentaprenyl diphosphate transport (reversible) pentaprenyl diphosphate --> pentaprenyl diphosphate 0.0 r_1243 phenethyl acetate transport phenethyl acetate --> phenethyl acetate 0.0 -r_1244_EXP_1 phosphate transport 1.5821717171717171 prot_P38361 + H+ + phosphate --> H+ + phosphate 0.027952688297521157 +r_1244_EXP_1 phosphate transport 1.5821717171717171 prot_P38361 + H+ + phosphate --> H+ + phosphate 0.0279526882977384 r_1244_EXP_2 phosphate transport 2.5893939393939394 prot_P25360 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_3 phosphate transport 2.4668939393939393 prot_P39535 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_4 phosphate transport 1.6258080808080808 prot_P25297 + H+ + phosphate --> H+ + phosphate 0.0 @@ -1687,8 +1687,8 @@ r_1263_REV_EXP_2 spermine transport (reversible) 14.118248201928578 prot_Q07824 r_1263_REV_EXP_3 spermine transport (reversible) 4.735615277275769 prot_Q12256 + H+ + spermine --> H+ + spermine 0.0 r_1263_REV_EXP_4 spermine transport (reversible) 5.6450672243090425 prot_Q06451 + H+ + spermine --> H+ + spermine 0.0 r_1264 succinate transport 0.32879485380079526 prot_Q06143 + phosphate + succinate --> phosphate + succinate 0.0 -r_1265 succinate-fumarate transport 0.5875590154537462 prot_P33303 + fumarate + succinate --> fumarate + succinate 0.010726833614579979 -r_1266_EXP_1 sulfate uniport 2.4230050505050507 prot_P38359 + sulphate --> sulphate 0.013924916568870401 +r_1265 succinate-fumarate transport 0.5875590154537462 prot_P33303 + fumarate + succinate --> fumarate + succinate 0.010726833614579982 +r_1266_EXP_1 sulfate uniport 2.4230050505050507 prot_P38359 + sulphate --> sulphate 0.01392491656887055 r_1266_EXP_2 sulfate uniport 2.516439393939394 prot_Q12325 + sulphate --> sulphate 0.0 r_1267 sulfite transport 296.1052693373152 prot_P41930 + sulphite --> sulphite 0.0 r_1268 taurine transport taurine --> taurine 0.0 @@ -1705,7 +1705,7 @@ r_1275 UTP transport 0.3655624733979681 prot_P38127 + FMN + H+ + UMP + UTP --> F r_1276 UTP/UMP antiport 0.3655624733979681 prot_P38127 + 2.0 H+ + UMP + UTP --> 2.0 H+ + UMP + UTP 0.0 r_1277_EXP_1 water diffusion 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_1277_EXP_2 water diffusion 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_1277_REV_EXP_1 water diffusion (reversible) 0.4050171892049932 prot_P0CD90 + H2O --> H2O 6.784795892257734 +r_1277_REV_EXP_1 water diffusion (reversible) 0.4050171892049932 prot_P0CD90 + H2O --> H2O 6.784967488655567 r_1277_REV_EXP_2 water diffusion (reversible) 0.77827345573678 prot_P0CD91 + H2O --> H2O 0.0 r_1278_EXP_1 zymosterol transport 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 0.0 r_1278_EXP_2 zymosterol transport 254.30179320863886 prot_Q08409 + zymosterol --> zymosterol 0.0 @@ -1765,12 +1765,12 @@ r_1566 2'-deoxyuridine exchange 2'-deoxyuridine --> 0.0 r_1567 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.0 r_1567_REV 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport (reversible) 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.03127094379016974 r_1568 2-dehydropantoate transport 2-dehydropantoate --> 2-dehydropantoate 0.0 -r_1568_REV 2-dehydropantoate transport (reversible) 2-dehydropantoate --> 2-dehydropantoate 1.900000061120133e-05 +r_1568_REV 2-dehydropantoate transport (reversible) 2-dehydropantoate --> 2-dehydropantoate 1.9000000611330134e-05 r_1572 2-isopropylmalate exchange 2-isopropylmalate --> 0.0 r_1573 2-isopropylmalate transport 2-isopropylmalate --> 2-isopropylmalate 0.0 r_1573_REV 2-isopropylmalate transport (reversible) 2-isopropylmalate --> 2-isopropylmalate 0.0 r_1574 2-isopropylmalate transport 0.6302029418767878 prot_P32332 + 2-isopropylmalate --> 2-isopropylmalate 0.0 -r_1574_REV 2-isopropylmalate transport (reversible) 0.6302029418767878 prot_P32332 + 2-isopropylmalate --> 2-isopropylmalate 0.032106964327030856 +r_1574_REV 2-isopropylmalate transport (reversible) 0.6302029418767878 prot_P32332 + 2-isopropylmalate --> 2-isopropylmalate 0.03210696432638382 r_1575 2-methyl-1-butanol transport 2-methylbutanol --> 2-methylbutanol 0.0 r_1575_REV 2-methyl-1-butanol transport (reversible) 2-methylbutanol --> 2-methylbutanol 0.0 r_1576 2-methyl-1-butanol transport 2-methylbutanol --> 2-methylbutanol 0.0 @@ -1817,7 +1817,7 @@ r_1603 4-amino-5-hydroxymethyl-2-methylpyrimidine synthetase 2.0579120900093906 r_1604 4-aminobenzoate exchange 4-aminobenzoate --> 0.0 r_1605 4-aminobenzoate transport 4-aminobenzoate --> 4-aminobenzoate 0.0 r_1605_REV 4-aminobenzoate transport (reversible) 4-aminobenzoate --> 4-aminobenzoate 0.0 -r_1606 4-aminobenzoate transport 4-aminobenzoate --> 4-aminobenzoate 6.3400002545677125e-06 +r_1606 4-aminobenzoate transport 4-aminobenzoate --> 4-aminobenzoate 6.340000254623224e-06 r_1606_REV 4-aminobenzoate transport (reversible) 4-aminobenzoate --> 4-aminobenzoate 0.0 r_1607 4-aminobutanal transport 4-aminobutanal --> 4-aminobutanal 0.0 r_1607_REV 4-aminobutanal transport (reversible) 4-aminobutanal --> 4-aminobutanal 0.0 @@ -1844,7 +1844,7 @@ r_1620 5'-nucleotidase (XMP) 0.5934259259259259 prot_standard + H2O + xanthosine r_1621 5-aminolevulinate exchange 5-aminolevulinate --> 0.0 r_1622 5-aminolevulinate transport 5-aminolevulinate --> 5-aminolevulinate 0.0 r_1622_REV 5-aminolevulinate transport (reversible) 5-aminolevulinate --> 5-aminolevulinate 0.0 -r_1623 5-formethyltetrahydrofolate cyclo-ligase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP --> 5,10-methenyl-THF + ADP + phosphate 0.2848213125470931 +r_1623 5-formethyltetrahydrofolate cyclo-ligase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP --> 5,10-methenyl-THF + ADP + phosphate 0.0 r_1624 5-formyltetrahydrofolate:10-formyltetrahydrofolate isomerase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP + H2O --> 10-formyl-THF + ADP + H+ + phosphate 0.0 r_1625 5-formyltetrahydrofolic acid exchange 5-formyltetrahydrofolic acid --> 0.0 r_1627 7,8-diaminononanoate exchange 7,8-diaminononanoate --> 0.0 @@ -1854,7 +1854,7 @@ r_1629 8-amino-7-oxononanoate exchange 8-amino-7-oxononanoate --> 0.0 r_1630 9H-xanthine exchange 9H-xanthine --> 0.0 r_1631 acetaldehyde exchange acetaldehyde --> 0.0 r_1632 acetaldehyde transport acetaldehyde --> acetaldehyde 0.0 -r_1632_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 1.5897186759374708 +r_1632_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.26208142457649936 r_1633 acetaldehyde transport acetaldehyde --> acetaldehyde 0.0 r_1633_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.0 r_1634 acetate exchange acetate --> 0.232781666 @@ -1862,7 +1862,7 @@ r_1635 acetate transport acetate --> acetate 0.0 r_1635_REV acetate transport (reversible) acetate --> acetate 0.0 r_1637 acetyl-CoA transport acetyl-CoA --> acetyl-CoA 0.0 r_1637_REV acetyl-CoA transport (reversible) acetyl-CoA --> acetyl-CoA 0.0 -r_1638 acetylcarnitine transport O-acetylcarnitine --> O-acetylcarnitine 0.007202150381957033 +r_1638 acetylcarnitine transport O-acetylcarnitine --> O-acetylcarnitine 0.0 r_1639 adenine exchange adenine --> 0.0 r_1640 adenine transport adenine --> adenine 0.0 r_1640_REV adenine transport (reversible) adenine --> adenine 0.0 @@ -1882,7 +1882,7 @@ r_1650 trehalose exchange trehalose --> 0.0 r_1651 alpha-D-glucosamine 6-phosphate exchange alpha-D-glucosamine 6-phosphate --> 0.0 r_1652 alpha-ketoglutarate/malate transporter (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 r_1652_REV alpha-ketoglutarate/malate transporter (reversible) (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 -r_1654 ammonium exchange ammonium <=> -0.9730850971666676 +r_1654 ammonium exchange ammonium <=> -0.9730850971669617 r_1656 AMP transport AMP --> AMP 0.0 r_1656_REV AMP transport (reversible) AMP --> AMP 0.0 r_1657 arginine transport 25.141189431578304 prot_P38279 + H+ + L-arginine --> H+ + L-arginine 0.0 @@ -1898,7 +1898,7 @@ r_1664 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + r_1664_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1665 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + H2O --> bicarbonate + H+ 0.0 r_1665_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 -r_1667 bicarbonate formation 7.346040189125295e-06 prot_P53615 + carbon dioxide + H2O --> bicarbonate + H+ 0.4245767379971571 +r_1667 bicarbonate formation 7.346040189125295e-06 prot_P53615 + carbon dioxide + H2O --> bicarbonate + H+ 0.4348287145582337 r_1667_REV bicarbonate formation (reversible) 7.346040189125295e-06 prot_P53615 + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1668 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + H2O --> bicarbonate + H+ 0.0 r_1668_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 @@ -1906,8 +1906,8 @@ r_1669 bicarbonate transport bicarbonate --> bicarbonate 0.0 r_1669_REV bicarbonate transport (reversible) bicarbonate --> bicarbonate 0.0 r_1671 biotin exchange biotin --> 0.0 r_1672 carbon dioxide exchange carbon dioxide --> 5.799021406960001 -r_1673 carnitine transport (R)-carnitine --> (R)-carnitine 0.007202150381957033 -r_1674 carnitine-acetylcarnitine carrier (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.0 +r_1673 carnitine transport (R)-carnitine --> (R)-carnitine 0.0 +r_1674 carnitine-acetylcarnitine carrier (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.007019930692418554 r_1675 CDP transport CDP --> CDP 0.0 r_1675_REV CDP transport (reversible) CDP --> CDP 0.0 r_1676 ceramide transport ceramide-1 (C24) --> ceramide-1 (C24) 0.0 @@ -1925,7 +1925,7 @@ r_1681_REV ceramide transport (reversible) ceramide-4 (C26) --> ceramide-4 (C26) r_1682 cholestenol delta-isomerase, lumped reaction 2.489610027058053 prot_standard + oxygen + S-adenosyl-L-methionine + zymosterol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + 2.0 H2O + S-adenosyl-L-homocysteine 0.003356619460625601 r_1683 choline exchange choline --> 0.0 r_1684_EXP_1 choline transport 49.19344031664132 prot_P19807 + choline --> choline 0.0 -r_1684_EXP_2 choline transport 4.890140948879145 prot_Q12412 + choline --> choline 0.0036216614344410166 +r_1684_EXP_2 choline transport 4.890140948879145 prot_Q12412 + choline --> choline 0.0036216615321250254 r_1684_REV_EXP_1 choline transport (reversible) 49.19344031664132 prot_P19807 + choline --> choline 0.0 r_1684_REV_EXP_2 choline transport (reversible) 4.890140948879145 prot_Q12412 + choline --> choline 0.0 r_1685 chorismate pyruvate lyase 0.6162073031087573 prot_standard + chorismate --> 4-hydroxybenzoate + pyruvate 0.0 @@ -1934,7 +1934,7 @@ r_1686_REV citrate transport (reversible) citrate --> citrate 0.0 r_1687 citrate exchange citrate --> 0.0 r_1688 citrate/isocitrate antiport citrate + isocitrate --> citrate + isocitrate 0.0 r_1688_REV citrate/isocitrate antiport (reversible) citrate + isocitrate --> citrate + isocitrate 0.0 -r_1689 citrate/malate antiport (S)-malate + citrate --> (S)-malate + citrate 0.008034867649931332 +r_1689 citrate/malate antiport (S)-malate + citrate --> (S)-malate + citrate 0.008034867650467552 r_1689_REV citrate/malate antiport (reversible) (S)-malate + citrate --> (S)-malate + citrate 0.0 r_1690 CMP nucleosidase 0.9660422049956934 prot_standard + CMP + H2O --> cytosine + ribose-5-phosphate 0.0 r_1691 CO2 transport carbon dioxide --> carbon dioxide 0.0 @@ -1944,17 +1944,17 @@ r_1694_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1695 CO2 transport carbon dioxide --> carbon dioxide 0.0 r_1695_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1696 CO2 transport carbon dioxide --> carbon dioxide 0.0 -r_1696_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 1.7624994547456938 +r_1696_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 3.131368499478553 r_1697 CO2 transport carbon dioxide --> carbon dioxide 5.799021406960001 r_1697_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1698 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1698_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 r_1699 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1699_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 -r_1700 coenzyme A transport coenzyme A --> coenzyme A 0.0033942245256211303 +r_1700 coenzyme A transport coenzyme A --> coenzyme A 0.003383601226810361 r_1700_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 r_1702 cytidine exchange cytidine --> 0.0 -r_1703 cytidylate kinase (CMP) 0.015537262872628726 prot_P15700 + ATP + CMP --> ADP + CDP 0.006460954116156428 +r_1703 cytidylate kinase (CMP) 0.015537262872628726 prot_P15700 + ATP + CMP --> ADP + CDP 0.006460954213813954 r_1704 cytidylate kinase (dCMP) 0.0872640791476408 prot_P15700 + ATP + dCMP --> ADP + dCDP 0.0 r_1704_REV cytidylate kinase (dCMP) (reversible) 0.6446121633029441 prot_P15700 + ADP + dCDP --> ATP + dCMP 0.0 r_1705 cytosine exchange cytosine --> 0.0 @@ -1995,7 +1995,7 @@ r_1724 ADP deamination 0.5934259259259259 prot_standard + ADP + H+ + H2O --> amm r_1725 dADP deamination 0.5934259259259259 prot_standard + dADP + H+ + H2O --> ammonium + dIDP 0.0 r_1726 deamino-NAD+ diffusion deamido-NAD(+) --> deamido-NAD(+) 0.0 r_1726_REV deamino-NAD+ diffusion (reversible) deamido-NAD(+) --> deamido-NAD(+) 0.0 -r_1727 decanoate exchange decanoate --> 0.002415660218418773 +r_1727 decanoate exchange decanoate --> 0.0024499794964130558 r_1728 deoxyadenosine transport 2'-deoxyadenosine --> 2'-deoxyadenosine 0.0 r_1729 deoxyadenylate kinase 0.007176741835638936 prot_Q12055 + ATP + dAMP --> ADP + dADP 0.0 r_1729_REV deoxyadenylate kinase (reversible) 0.008061231729814105 prot_Q12055 + ADP + dADP --> ATP + dAMP 0.00035999999381601804 @@ -2005,17 +2005,17 @@ r_1732 deoxyguanosine transport 2'-deoxyguanosine --> 2'-deoxyguanosine 0.0 r_1733 deoxyinosine transport 2'-deoxyinosine --> 2'-deoxyinosine 0.0 r_1734 deoxyuridine kinase (ATP:deoxyuridine) 0.9660422049956934 prot_standard + 2'-deoxyuridine + ATP --> ADP + dUMP + H+ 0.0 r_1735 deoxyuridine transport 3.240537611534019 prot_P38196 + 2'-deoxyuridine --> 2'-deoxyuridine 0.0 -r_1736 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 0.011148385396473228 +r_1736 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 0.011148385396473356 r_1737 dGDP transport dGDP --> dGDP 0.0 r_1737_REV dGDP transport (reversible) dGDP --> dGDP 0.0 -r_1738 dhnpt transport 7,8-dihydroneopterin --> 7,8-dihydroneopterin 6.3400002545677125e-06 +r_1738 dhnpt transport 7,8-dihydroneopterin --> 7,8-dihydroneopterin 6.340000254623224e-06 r_1738_REV dhnpt transport (reversible) 7,8-dihydroneopterin --> 7,8-dihydroneopterin 0.0 r_1739 diamine transaminase 1.1676441038721457 prot_Q12447 + acetyl-CoA + spermine --> coenzyme A + H+ + N(1)-acetylspermine 0.0 r_1743 dihydrofolate transport dihydrofolic acid --> dihydrofolic acid 0.0 r_1743_REV dihydrofolate transport (reversible) dihydrofolic acid --> dihydrofolic acid 0.0 r_1744 dihydroneopterin triphosphate pyrophosphatase 6.230972222222222 prot_standard + 7,8-dihydroneopterin 3'-triphosphate + H2O --> 7,8-dihydroneopterin 3'-phosphate + diphosphate + H+ 0.0 r_1745 dihydropteroate transport 7,8-dihydropteroate --> 7,8-dihydropteroate 0.0 -r_1745_REV dihydropteroate transport (reversible) 7,8-dihydropteroate --> 7,8-dihydropteroate 6.3400002545677125e-06 +r_1745_REV dihydropteroate transport (reversible) 7,8-dihydropteroate --> 7,8-dihydropteroate 6.340000254623224e-06 r_1746 dihydroxyacetone phosphate transport dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_1746_REV dihydroxyacetone phosphate transport (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_1747 diphosphate transport diphosphate --> diphosphate 0.0 @@ -2037,8 +2037,8 @@ r_1758 ergosterol transport ergosterol --> ergosterol 0.0 r_1758_REV ergosterol transport (reversible) ergosterol --> ergosterol 0.0 r_1759 ergosterol transport ergosterol --> ergosterol 0.0 r_1759_REV ergosterol transport (reversible) ergosterol --> ergosterol 0.0 -r_1761 ethanol exchange ethanol --> 0.7469003224717745 -r_1762 ethanol transport ethanol --> ethanol 0.7469003224717745 +r_1761 ethanol exchange ethanol --> 0.7467287260775288 +r_1762 ethanol transport ethanol --> ethanol 0.7467287260775288 r_1762_REV ethanol transport (reversible) ethanol --> ethanol 0.0 r_1763 ethanol transport, mitochondrial ethanol --> ethanol 0.0 r_1763_REV ethanol transport, mitochondrial (reversible) ethanol --> ethanol 0.0 @@ -2047,13 +2047,13 @@ r_1765 ethyl acetate exchange ethyl acetate --> 0.0 r_1766 farnesyl diphosphate transport farnesyl diphosphate --> farnesyl diphosphate 0.0 r_1766_REV farnesyl diphosphate transport (reversible) farnesyl diphosphate --> farnesyl diphosphate 0.0 r_1770 fatty acid transport 0.6366271866276696 prot_P38225 + decanoate --> decanoate 0.0 -r_1770_REV fatty acid transport (reversible) 0.6366271866276696 prot_P38225 + decanoate --> decanoate 0.002415660218418773 +r_1770_REV fatty acid transport (reversible) 0.6366271866276696 prot_P38225 + decanoate --> decanoate 0.0024499794964130558 r_1771 fatty acid transport 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + laurate --> laurate 0.0 r_1771_REV fatty acid transport (reversible) 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + laurate --> laurate 0.00044172356996047285 r_1772 fatty acid transport 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + myristate --> myristate 0.0 -r_1772_REV fatty acid transport (reversible) 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + myristate --> myristate 0.00025539365650321597 +r_1772_REV fatty acid transport (reversible) 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + myristate --> myristate 0.00025539366341234895 r_1774 fatty acid transport 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + palmitate --> palmitate 0.0 -r_1774_REV fatty acid transport (reversible) 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + palmitate --> palmitate 1.1847279353553024e-12 +r_1774_REV fatty acid transport (reversible) 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + palmitate --> palmitate -5.504618137176787e-12 r_1775 fatty acid transport 0.44480530037780946 prot_P38225 + palmitoleate --> palmitoleate 0.0 r_1775_REV fatty acid transport (reversible) 0.44480530037780946 prot_P38225 + palmitoleate --> palmitoleate 0.0 r_1776 fatty acid transport octanoate --> octanoate 0.0 @@ -2086,14 +2086,14 @@ r_1807 glutathione exchange glutathione --> 0.0 r_1808 glycerol exchange glycerol --> 0.06402693448 r_1809 glycerol-3-phosphate shuttle glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_1809_REV glycerol-3-phosphate shuttle (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 -r_1810 L-glycine exchange L-glycine --> 0.32287972421607625 +r_1810 L-glycine exchange L-glycine --> 0.32287972421523614 r_1811 glycine transport 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 0.0 -r_1811_REV glycine transport (reversible) 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 1.900000061120133e-05 +r_1811_REV glycine transport (reversible) 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 1.9000000611330134e-05 r_1812 glycoaldehyde transport glycolaldehyde --> glycolaldehyde 0.0 -r_1812_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 6.3400002545677125e-06 +r_1812_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 6.340000254623224e-06 r_1813 glycoaldehyde transport glycolaldehyde --> glycolaldehyde 0.0 -r_1813_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 6.4600002588122155e-06 -r_1814 glycolaldehyde exchange glycolaldehyde --> 6.4600002588122155e-06 +r_1813_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 6.460000258867727e-06 +r_1814 glycolaldehyde exchange glycolaldehyde --> 6.460000258867727e-06 r_1815 glyoxylate exchange glyoxylate --> 0.0 r_1816 glyoxylate transport 200.53975994321283 prot_P53943 + glyoxylate --> glyoxylate 0.0 r_1816_REV glyoxylate transport (reversible) 200.53975994321283 prot_P53943 + glyoxylate --> glyoxylate 0.0 @@ -2107,19 +2107,19 @@ r_1821 guanosine kinase 0.5934259259259259 prot_standard + ATP + guanosine --> A r_1822 guanosine transport guanosine --> guanosine 0.0 r_1823 guanosine transport guanosine --> guanosine 0.0 r_1824 H+ diffusion H+ --> H+ 0.0 -r_1825 H+ diffusion H+ --> H+ 0.007412363922045165 +r_1825 H+ diffusion H+ --> H+ 0.007412363922328585 r_1825_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1826 H+ diffusion H+ --> H+ 0.0 r_1826_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1827 H+ diffusion H+ --> H+ 0.0 -r_1827_REV H+ diffusion (reversible) H+ --> H+ 0.0005472067037335731 +r_1827_REV H+ diffusion (reversible) H+ --> H+ 0.0005472083134696547 r_1829 H+ diffusion H+ --> H+ 0.0 r_1829_REV H+ diffusion (reversible) H+ --> H+ 0.0 -r_1830 H+ diffusion H+ --> H+ 0.0035264787767822466 +r_1830 H+ diffusion H+ --> H+ 0.0034398687716009043 r_1830_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1831 H+ diffusion H+ --> H+ 0.10856224543938205 r_1831_REV H+ diffusion (reversible) H+ --> H+ 0.0 -r_1832 H+ exchange H+ <=> 1.409730511582096 +r_1832 H+ exchange H+ <=> 1.3508549951010966 r_1833 hexacosanoyl-CoA transport hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_1833_REV hexacosanoyl-CoA transport (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_1834 hexadecanal exchange hexadecanal --> 0.0 @@ -2133,7 +2133,7 @@ r_1838_EXP_2 homocitrate synthase 10.507993633138625 prot_P48570 + 2-oxoglutarat r_1839 hydrogen peroxide transport hydrogen peroxide --> hydrogen peroxide 0.0 r_1839_REV hydrogen peroxide transport (reversible) hydrogen peroxide --> hydrogen peroxide 0.0 r_1840 hydroxymethylglutaryl-CoA transport 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.0 -r_1840_REV hydroxymethylglutaryl-CoA transport (reversible) 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.022347724063098005 +r_1840_REV hydroxymethylglutaryl-CoA transport (reversible) 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.022347724064798527 r_1841 hypoxanthine exchange hypoxanthine --> 0.0 r_1842 hypoxanthine transport hypoxanthine --> hypoxanthine 0.0 r_1842_REV hypoxanthine transport (reversible) hypoxanthine --> hypoxanthine 0.0 @@ -2293,13 +2293,13 @@ r_1928 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide C (C26 r_1928_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide C (C26) --> inositol phosphomannosylinositol phosphoceramide C (C26) 0.0 r_1929 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide D (C26) --> inositol phosphomannosylinositol phosphoceramide D (C26) 0.0 r_1929_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide D (C26) --> inositol phosphomannosylinositol phosphoceramide D (C26) 0.0 -r_1930 malate/oxaloacetate shuttle (S)-malate + oxaloacetate --> (S)-malate + oxaloacetate 0.022990438602265767 +r_1930 malate/oxaloacetate shuttle (S)-malate + oxaloacetate --> (S)-malate + oxaloacetate 0.02285316149082454 r_1930_REV malate/oxaloacetate shuttle (reversible) (S)-malate + oxaloacetate --> (S)-malate + oxaloacetate 0.0 r_1931 maltose exchange maltose --> 0.0 r_1932 mannan transport mannan --> mannan 0.0 r_1932_REV mannan transport (reversible) mannan --> mannan 0.070204 r_1935 methionine transport 6.982964031081571 prot_P48813 + L-methionine --> L-methionine 0.0 -r_1936 methylglyoxal synthase 1.1329040404040405 prot_standard + dihydroxyacetone phosphate --> methylglyoxal + phosphate 0.025740539293600064 +r_1936 methylglyoxal synthase 1.1329040404040405 prot_standard + dihydroxyacetone phosphate --> methylglyoxal + phosphate 0.0722727950276578 r_1937 MIPC transport mannosylinositol phosphorylceramide A (C24) --> mannosylinositol phosphorylceramide A (C24) 0.0 r_1937_REV MIPC transport (reversible) mannosylinositol phosphorylceramide A (C24) --> mannosylinositol phosphorylceramide A (C24) 0.0 r_1938 MIPC transport mannosylinositol phosphorylceramide B (C24) --> mannosylinositol phosphorylceramide B (C24) 0.0 @@ -2323,8 +2323,8 @@ r_1946_REV MIPC transport (reversible) mannosylinositol phosphorylceramide D (C2 r_1947 myo-inositol exchange myo-inositol --> 0.0 r_1952 N,N'-diformyldityrosine exchange N,N'-diformyldityrosine --> 0.0 r_1963 NADP(+) transport NADP(+) --> NADP(+) 0.0 -r_1963_REV NADP(+) transport (reversible) NADP(+) --> NADP(+) 0.007412363922045165 -r_1964 NADPH transport NADPH --> NADPH 0.007412363922045165 +r_1963_REV NADP(+) transport (reversible) NADP(+) --> NADP(+) 0.007412363922328585 +r_1964 NADPH transport NADPH --> NADPH 0.007412363922328585 r_1964_REV NADPH transport (reversible) NADPH --> NADPH 0.0 r_1965 NH3 transport ammonium --> ammonium 0.0 r_1965_REV NH3 transport (reversible) ammonium --> ammonium 0.0 @@ -2340,13 +2340,13 @@ r_1972 NMN transport NMN --> NMN 0.0 r_1974 nucleoside-diphosphatase (dGDP) 0.5934259259259259 prot_standard + dGDP + H2O --> dGMP + H+ + phosphate 0.0 r_1975 nucleoside-triphosphatase (dGTP) 0.5934259259259259 prot_standard + dGTP + H2O --> dGDP + H+ + phosphate 0.0 r_1976 O-acetylcarnintine transport into mitochondria 1.094665810308139 prot_Q12289 + O-acetylcarnitine --> O-acetylcarnitine 0.0 -r_1977 O2 transport oxygen --> oxygen 0.003724620677183001 +r_1977 O2 transport oxygen --> oxygen 0.003724620677466421 r_1977_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1978 O2 transport oxygen --> oxygen 4.856539744391012 +r_1978 O2 transport oxygen --> oxygen 4.877215293902399 r_1978_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1979 O2 transport oxygen --> oxygen 4.954133177486228 +r_1979 O2 transport oxygen --> oxygen 4.954167496766072 r_1979_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1980 O2 transport oxygen --> oxygen 0.014674123872780763 +r_1980 O2 transport oxygen --> oxygen 0.014621833146349737 r_1980_REV O2 transport (reversible) oxygen --> oxygen 0.0 r_1981 octadecanoate (n-C18:0) transport 0.6366271866276696 prot_P38225 + stearate --> stearate 0.0 r_1981_REV octadecanoate (n-C18:0) transport (reversible) 0.6366271866276696 prot_P38225 + stearate --> stearate 0.0 @@ -2357,8 +2357,8 @@ r_1988_REV oxaloacetate transport (reversible) oxaloacetate --> oxaloacetate 0.0 r_1989 oxaloacetate(2-) exchange oxaloacetate --> 0.0 r_1990 oxidized glutathione uniport 6.850627360229916 prot_P40897 + glutathione disulfide --> glutathione disulfide 0.0 r_1991 oxidized thioredoxin transport TRX1 disulphide --> TRX1 disulphide 0.0 -r_1991_REV oxidized thioredoxin transport (reversible) TRX1 disulphide --> TRX1 disulphide 0.01467412387278076 -r_1992 oxygen exchange oxygen <-- -4.954133177486228 +r_1991_REV oxidized thioredoxin transport (reversible) TRX1 disulphide --> TRX1 disulphide 0.014621833146349733 +r_1992 oxygen exchange oxygen <-- -4.954167496766072 r_1993 palmitate exchange palmitate --> 0.0 r_1994 palmitoleate exchange palmitoleate --> 0.0 r_1995 palmitoyl-CoA transport palmitoyl-CoA --> palmitoyl-CoA 0.0 @@ -2376,7 +2376,7 @@ r_2002_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phen r_2003 phenylacetaldehyde transport phenylacetaldehyde --> phenylacetaldehyde 0.0 r_2003_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phenylacetaldehyde 0.0 r_2004 phenylalanine transport L-phenylalanine --> L-phenylalanine 0.0 -r_2005 phosphate exchange phosphate <=> -0.027952688297521157 +r_2005 phosphate exchange phosphate <=> -0.0279526882977384 r_2008 phosphate transport 2.5123737373737374 prot_P27514 + phosphate --> phosphate 0.0 r_2008_REV phosphate transport (reversible) 2.5123737373737374 prot_P27514 + phosphate --> phosphate 0.0 r_2020 potassium exchange potassium <=> -0.000362999993376434 @@ -2393,14 +2393,14 @@ r_2029 pyridoxine kinase 0.08096311475409836 prot_P39988 + ATP + pyridoxine --> r_2030 pyrimidine phosphatase 3.5775737902860114 prot_standard + 5-amino-6-(5-phosphoribitylamino)uracil + H2O --> 5-amino-6-(D-ribitylamino)uracil + phosphate 9.999999710998968e-05 r_2031 pyrimidine-nucleoside phosphorylase (uracil) 0.9660422049956934 prot_standard + phosphate + uridine --> alpha-D-ribose 1-phosphate(2-) + uracil 0.0 r_2031_REV pyrimidine-nucleoside phosphorylase (uracil) (reversible) 0.9660422049956934 prot_standard + alpha-D-ribose 1-phosphate(2-) + uracil --> phosphate + uridine 0.0 -r_2032 pyrophosphate transport diphosphate --> diphosphate 0.0 -r_2032_REV pyrophosphate transport (reversible) diphosphate --> diphosphate 0.0715191425799532 +r_2032 pyrophosphate transport diphosphate --> diphosphate 0.02080434407078508 +r_2032_REV pyrophosphate transport (reversible) diphosphate --> diphosphate 0.0 r_2033 pyruvate exchange pyruvate --> 0.0 r_2034_EXP_1 pyruvate transport 0.010426331697901588 prot_P53157 + 0.011285052581323294 prot_P53311 + H+ + pyruvate --> H+ + pyruvate 0.0 r_2034_EXP_2 pyruvate transport 0.011066557295101342 prot_P38857 + 0.011401101108900353 prot_P53157 + H+ + pyruvate --> H+ + pyruvate 0.0 r_2036 quinolinate transport quinolinate --> quinolinate 0.0 r_2036_REV quinolinate transport (reversible) quinolinate --> quinolinate 0.0 -r_2037 reduced thioredoxin transport TRX1 --> TRX1 0.01467412387278076 +r_2037 reduced thioredoxin transport TRX1 --> TRX1 0.014621833146349733 r_2037_REV reduced thioredoxin transport (reversible) TRX1 --> TRX1 0.0 r_2038 riboflavin exchange riboflavin --> 0.0 r_2039 riboflavin transport riboflavin --> riboflavin 0.0 @@ -2411,23 +2411,23 @@ r_2042 S-adenosyl-L-homocysteine transport S-adenosyl-L-homocysteine --> S-adeno r_2042_REV S-adenosyl-L-homocysteine transport (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.0 r_2043 S-adenosyl-L-methionine exchange S-adenosyl-L-methionine --> 0.0 r_2044 S-methyl-L-methionine exchange S-methyl-L-methionine --> 0.0 -r_2045 serine transport 7.412955094957308 prot_P48813 + L-serine --> L-serine 1.900000061120133e-05 +r_2045 serine transport 7.412955094957308 prot_P48813 + L-serine --> L-serine 1.9000000611330134e-05 r_2045_REV serine transport (reversible) 7.412955094957308 prot_P48813 + L-serine --> L-serine 0.0 r_2046 sn-glycero-3-phosphocholine exchange sn-glycero-3-phosphocholine --> 0.0 r_2049 sodium exchange sodium <=> -0.0003969999961555 r_2050 spermidine acetyltransferase 0.31953703703703706 prot_standard + acetyl-CoA + spermidine --> coenzyme A + H+ + N(1)-acetylspermidine 0.0 r_2051 spermidine exchange spermidine --> 0.0 r_2052 spermine exchange spermine --> 0.0 -r_2053 squalene transport squalene --> squalene 0.003724620677183001 +r_2053 squalene transport squalene --> squalene 0.003724620677466421 r_2053_REV squalene transport (reversible) squalene --> squalene 0.0 -r_2054 squalene-2,3-epoxide transport (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.003724620677183001 +r_2054 squalene-2,3-epoxide transport (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.003724620677466421 r_2054_REV squalene-2,3-epoxide transport (reversible) (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.0 r_2055 stearate exchange stearate --> 0.0 r_2056 succinate exchange succinate --> 0.0 r_2057 succinate transport succinate --> succinate 0.0 r_2057_REV succinate transport (reversible) succinate --> succinate 0.0 r_2058 sucrose exchange sucrose --> 0.0 -r_2060 sulphate exchange sulphate <=> -0.013924916568870401 +r_2060 sulphate exchange sulphate <=> -0.01392491656887055 r_2061 sulphite exchange sulphite --> 0.0 r_2062 taurine exchange taurine --> 0.0 r_2063 tetracosanoyl-CoA transport tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 @@ -2461,22 +2461,22 @@ r_2090 uracil exchange uracil --> 0.0 r_2091 urea exchange urea --> 0.0 r_2092 uridine exchange uridine --> 0.0 r_2093 valine transport L-valine --> L-valine 0.0 -r_2093_REV valine transport (reversible) L-valine --> L-valine 0.03560582004496365 +r_2093_REV valine transport (reversible) L-valine --> L-valine 0.035605820045610685 r_2094_EXP_1 water diffusion 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_2094_EXP_2 water diffusion 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_2094_REV_EXP_1 water diffusion (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.003724620677183001 +r_2094_REV_EXP_1 water diffusion (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.003724620677466421 r_2094_REV_EXP_2 water diffusion (reversible) 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_2095 water diffusion H2O --> H2O 0.0 r_2095_REV water diffusion (reversible) H2O --> H2O 0.0 r_2096 water diffusion H2O --> H2O 0.0 -r_2096_REV water diffusion (reversible) H2O --> H2O 11.245652899296074 +r_2096_REV water diffusion (reversible) H2O --> H2O 12.145678186075333 r_2097 water diffusion H2O --> H2O 0.0 r_2097_REV water diffusion (reversible) H2O --> H2O 0.0 r_2098 water diffusion H2O --> H2O 0.0 -r_2098_REV water diffusion (reversible) H2O --> H2O 0.003245031697228573 +r_2098_REV water diffusion (reversible) H2O --> H2O 0.003243408077593645 r_2099 water diffusion H2O --> H2O 0.0 r_2099_REV water diffusion (reversible) H2O --> H2O 0.0 -r_2100 water exchange H2O <=> 6.784795892257734 +r_2100 water exchange H2O <=> 6.784967488655567 r_2101 xanthine transport 9H-xanthine --> 9H-xanthine 0.0 r_2101_REV xanthine transport (reversible) 9H-xanthine --> 9H-xanthine 0.0 r_2102 xanthosine exchange xanthosine --> 0.0 @@ -2496,33 +2496,33 @@ r_2111 growth biomass --> 0.1 r_2112 kynurenine aminotransferase 0.06921227197346601 prot_P47039 + L-kynurenine + pyruvate --> H2O + L-alanine + kynurenic acid 0.0 r_2112_REV kynurenine aminotransferase (reversible) 0.009033549783549784 prot_P47039 + H2O + L-alanine + kynurenic acid --> L-kynurenine + pyruvate 0.0 r_2113 spontaneous kynurenic acid to quinaldic acid 0.41264716703458426 prot_standard + 2.0 H+ + NADPH + kynurenic acid --> H2O + NADP(+) + quinaldic acid 0.0 -r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.41264716703458426 prot_standard + 2-amino-3-carboxymuconate-6-semialdehyde --> H+ + H2O + quinolinate 0.000606999997398135 +r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.41264716703458426 prot_standard + 2-amino-3-carboxymuconate-6-semialdehyde --> H+ + H2O + quinolinate 0.0006069999973967727 r_2115_EXP_1 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.03339649287148808 prot_P38113 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.0 -r_2115_EXP_2 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.011373148148148148 prot_P00330 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.7469003224717745 -r_2116_EXP_1 acetaldehyde dehydrogenase 0.06942013888888889 prot_Q04458 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 4.5636827650241685e-12 +r_2115_EXP_2 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.011373148148148148 prot_P00330 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.7467287260775288 +r_2116_EXP_1 acetaldehyde dehydrogenase 0.06942013888888889 prot_Q04458 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_2 acetaldehyde dehydrogenase 0.483596214511041 prot_P47771 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_3 acetaldehyde dehydrogenase 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_4 acetaldehyde dehydrogenase 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 -r_2117 phenylalanine transaminase 0.05744797801334904 prot_P38840 + L-phenylalanine + pyruvate --> keto-phenylpyruvate + L-alanine 0.04642458934431 +r_2117 phenylalanine transaminase 0.05744797801334904 prot_P38840 + L-phenylalanine + pyruvate --> keto-phenylpyruvate + L-alanine 0.046424589344309854 r_2117_REV phenylalanine transaminase (reversible) 0.010556998556998556 prot_P38840 + keto-phenylpyruvate + L-alanine --> L-phenylalanine + pyruvate 0.0 r_2118 tryptophan transaminase 0.05744797801334904 prot_P38840 + keto-phenylpyruvate + L-tryptophan --> indole-3-pyruvate + L-phenylalanine 0.0 -r_2119 tyrosine transaminase 0.010556998556998556 prot_P38840 + 3-(4-hydroxyphenyl)pyruvate + L-alanine --> L-tyrosine + pyruvate 0.012302566079285501 +r_2119 tyrosine transaminase 0.010556998556998556 prot_P38840 + 3-(4-hydroxyphenyl)pyruvate + L-alanine --> L-tyrosine + pyruvate 0.012302566079285503 r_2119_REV tyrosine transaminase (reversible) 0.11696243005595523 prot_P38840 + L-tyrosine + pyruvate --> 3-(4-hydroxyphenyl)pyruvate + L-alanine 0.0 r_2125 coenzyme A: cytoplasm to LP coenzyme A --> coenzyme A 0.0 -r_2125_REV coenzyme A: cytoplasm to LP (reversible) coenzyme A --> coenzyme A 0.00029994594906580915 +r_2125_REV coenzyme A: cytoplasm to LP (reversible) coenzyme A --> coenzyme A 0.0003771973053287472 r_2126 sedoheptulose bisphosphatase 2.051719576719577 prot_P36136 + H2O + sedoheptulose 1,7-bisphosphate --> phosphate + sedoheptulose 7-phosphate 0.0 r_2129 proton leak H+ --> H+ 0.0 r_2131 isocitrate dehydrogenase 0.47807539682539685 prot_P21954 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.0 -r_2132_EXP_1 oxoglutarate/malate exchange 0.3902368014935992 prot_Q99297 + (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.16391620721379474 -r_2132_EXP_2 oxoglutarate/malate exchange 2.6118993789038507 prot_Q03028 + (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 -r_2134 14-demethyllanosterol exchange 14-demethyllanosterol --> -1.2778450173001055e-13 -r_2136 14-demethyllanosterol transport 14-demethyllanosterol --> 14-demethyllanosterol 1.2778450173001055e-13 -r_2136_REV 14-demethyllanosterol transport (reversible) 14-demethyllanosterol --> 14-demethyllanosterol 0.0 +r_2132_EXP_1 oxoglutarate/malate exchange 0.3902368014935992 prot_Q99297 + (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.15287024836411067 +r_2132_EXP_2 oxoglutarate/malate exchange 2.6118993789038507 prot_Q03028 + (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.011045958849795368 +r_2134 14-demethyllanosterol exchange 14-demethyllanosterol --> 1.5563548713681818e-13 +r_2136 14-demethyllanosterol transport 14-demethyllanosterol --> 14-demethyllanosterol 0.0 +r_2136_REV 14-demethyllanosterol transport (reversible) 14-demethyllanosterol --> 14-demethyllanosterol 1.5563548713681818e-13 r_2137 ergosta-5,7,22,24(28)-tetraen-3beta-ol exchange ergosta-5,7,22,24(28)-tetraen-3beta-ol --> 0.0 r_2139 ergosta-5,7,22,24(28)-tetraen-3beta-ol transport ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 r_2139_REV ergosta-5,7,22,24(28)-tetraen-3beta-ol transport (reversible) ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 -r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 27.714912457481013 prot_P07149 + 25.079771343596047 prot_P19097 + acetyl-CoA + 21.0 H+ + 7.0 malonyl-CoA + 14.0 NADPH --> 7.0 carbon dioxide + 7.0 coenzyme A + 7.0 H2O + 14.0 NADP(+) + palmitoyl-CoA 0.012065014317168105 -r_2141 fatty-acyl-CoA synthase (n-C18:0CoA) 50.82022222222222 prot_P07149 + 45.98822222222222 prot_P19097 + acetyl-CoA + 24.0 H+ + 8.0 malonyl-CoA + 16.0 NADPH --> 8.0 carbon dioxide + 8.0 coenzyme A + 8.0 H2O + 16.0 NADP(+) + stearoyl-CoA 0.006991780824644111 +r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 27.714912457481013 prot_P07149 + 25.079771343596047 prot_P19097 + acetyl-CoA + 21.0 H+ + 7.0 malonyl-CoA + 14.0 NADPH --> 7.0 carbon dioxide + 7.0 coenzyme A + 7.0 H2O + 14.0 NADP(+) + palmitoyl-CoA 0.011980027931401956 +r_2141 fatty-acyl-CoA synthase (n-C18:0CoA) 50.82022222222222 prot_P07149 + 45.98822222222222 prot_P19097 + acetyl-CoA + 24.0 H+ + 8.0 malonyl-CoA + 16.0 NADPH --> 8.0 carbon dioxide + 8.0 coenzyme A + 8.0 H2O + 16.0 NADP(+) + stearoyl-CoA 0.0070661439113800205 r_2142 B-ketoacyl-ACP synthase (acetoacetyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + acetyl-ACP + carboxyacetyl-ACP --> carbon dioxide + ACP1 + acetoacetyl-ACP 0.0 r_2143 B-ketoacyl-ACP synthase (3-oxo-hexanoyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + carboxyacetyl-ACP + butanoyl-ACP --> carbon dioxide + ACP1 + 3-oxo-hexanoyl-ACP 0.0 r_2144 B-ketoacyl-ACP synthase (3-oxo-octanoyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + carboxyacetyl-ACP + hexanoyl-ACP --> carbon dioxide + ACP1 + 3-oxo-octanoyl-ACP 0.0 @@ -2539,48 +2539,48 @@ r_2151 enoyl-ACP reductase (butanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NA r_2152 enoyl-ACP reductase (hexanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NADPH + trans-hex-2-enoyl-ACP --> NADP(+) + hexanoyl-ACP 0.0 r_2153 enoyl-ACP reductase (octanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NADPH + trans-oct-2-enoyl-ACP --> NADP(+) + octanoyl-ACP 0.0 r_2154 elongase I (3-oxotetradecanoyl-CoA) 0.36517429674617 prot_P39540 + lauroyl-CoA + malonyl-CoA + H+ --> carbon dioxide + coenzyme A + 3-oxotetradecanoyl-CoA 0.00044172356996047285 -r_2155 elongase I (3-oxopalmitoyl-CoA) 0.36517429674617 prot_P39540 + malonyl-CoA + H+ + myristoyl-CoA --> carbon dioxide + coenzyme A + 3-oxopalmitoyl-CoA 0.0006971172264636886 +r_2155 elongase I (3-oxopalmitoyl-CoA) 0.36517429674617 prot_P39540 + malonyl-CoA + H+ + myristoyl-CoA --> carbon dioxide + coenzyme A + 3-oxopalmitoyl-CoA 0.0006971172333728216 r_2156 elongase II (3-oxooctadecanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + palmitoyl-CoA --> carbon dioxide + coenzyme A + 3-oxooctadecanoyl-CoA 0.0 r_2157_EXP_1 elongase II or III (3-oxoicosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + stearoyl-CoA --> carbon dioxide + coenzyme A + 3-oxoicosanoyl-CoA 0.0 -r_2157_EXP_2 elongase II or III (3-oxoicosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + stearoyl-CoA --> carbon dioxide + coenzyme A + 3-oxoicosanoyl-CoA 0.0003717106244277723 +r_2157_EXP_2 elongase II or III (3-oxoicosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + stearoyl-CoA --> carbon dioxide + coenzyme A + 3-oxoicosanoyl-CoA 0.0003717106243194283 r_2158_EXP_1 elongase II or III (3-oxodocosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + icosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxodocosanoyl-CoA 0.0 -r_2158_EXP_2 elongase II or III (3-oxodocosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + icosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxodocosanoyl-CoA 0.0003717106244277723 +r_2158_EXP_2 elongase II or III (3-oxodocosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + icosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxodocosanoyl-CoA 0.0003717106243194283 r_2159_EXP_1 elongase II or III (3-oxotetracosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + docosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxotetracosanoyl-CoA 0.0 -r_2159_EXP_2 elongase II or III (3-oxotetracosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + docosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxotetracosanoyl-CoA 0.0003717106244277723 -r_2160 elongase III (3-oxohexacosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + tetracosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxohexacosanoyl-CoA 0.0003717106244277723 +r_2159_EXP_2 elongase II or III (3-oxotetracosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + docosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxotetracosanoyl-CoA 0.0003717106243194283 +r_2160 elongase III (3-oxohexacosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + tetracosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxohexacosanoyl-CoA 0.0003717106243194283 r_2161 B-ketoacyl-CoA reductase ((S)-3-hydroxytetradecanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxotetradecanoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxytetradecanoyl-CoA 0.00044172356996047285 -r_2162 B-ketoacyl-CoA reductase ((S)-3-hydroxypalmitoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxopalmitoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxypalmitoyl-CoA 0.0006971172264636886 +r_2162 B-ketoacyl-CoA reductase ((S)-3-hydroxypalmitoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxopalmitoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxypalmitoyl-CoA 0.0006971172333728216 r_2163 B-ketoacyl-CoA reductase (3-hydroxyoctadecanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxooctadecanoyl-CoA + NADPH --> NADP(+) + 3-hydroxyoctadecanoyl-CoA 0.0 -r_2164 B-ketoacyl-CoA reductase (3-hydroxyicosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxoicosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxyicosanoyl-CoA 0.0003717106244277723 -r_2165 B-ketoacyl-CoA reductase (3-hydroxydocosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxodocosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxydocosanoyl-CoA 0.0003717106244277723 -r_2166 B-ketoacyl-CoA reductase (3-hydroxytetracosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxotetracosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxytetracosanoyl-CoA 0.0003717106244277723 -r_2167 B-ketoacyl-CoA reductase ((S)-3-hydroxyhexacosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxohexacosanoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxyhexacosanoyl-CoA 0.0003717106244277723 +r_2164 B-ketoacyl-CoA reductase (3-hydroxyicosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxoicosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxyicosanoyl-CoA 0.0003717106243194283 +r_2165 B-ketoacyl-CoA reductase (3-hydroxydocosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxodocosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxydocosanoyl-CoA 0.0003717106243194283 +r_2166 B-ketoacyl-CoA reductase (3-hydroxytetracosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxotetracosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxytetracosanoyl-CoA 0.0003717106243194283 +r_2167 B-ketoacyl-CoA reductase ((S)-3-hydroxyhexacosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxohexacosanoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxyhexacosanoyl-CoA 0.0003717106243194283 r_2168 B-hydroxyacyl-CoA dehydratase (trans-tetradec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxytetradecanoyl-CoA --> H2O + trans-tetradec-2-enoyl-CoA 0.00044172356996047285 r_2168_REV B-hydroxyacyl-CoA dehydratase (trans-tetradec-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-tetradec-2-enoyl-CoA --> (S)-3-hydroxytetradecanoyl-CoA 0.0 -r_2169 B-hydroxyacyl-CoA dehydratase (trans-hexadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxypalmitoyl-CoA --> H2O + trans-hexadec-2-enoyl-CoA 0.0006971172264636841 +r_2169 B-hydroxyacyl-CoA dehydratase (trans-hexadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxypalmitoyl-CoA --> H2O + trans-hexadec-2-enoyl-CoA 0.0006971172333728206 r_2169_REV B-hydroxyacyl-CoA dehydratase (trans-hexadec-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-hexadec-2-enoyl-CoA --> (S)-3-hydroxypalmitoyl-CoA 0.0 r_2170 B-hydroxyacyl-CoA dehydratase (trans-octadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxyoctadecanoyl-CoA --> H2O + trans-octadec-2-enoyl-CoA 0.0 r_2170_REV B-hydroxyacyl-CoA dehydratase (trans-octadec-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-octadec-2-enoyl-CoA --> 3-hydroxyoctadecanoyl-CoA 0.0 -r_2171 B-hydroxyacyl-CoA dehydratase (trans-icos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxyicosanoyl-CoA --> H2O + trans-icos-2-enoyl-CoA 0.0003717106244277723 +r_2171 B-hydroxyacyl-CoA dehydratase (trans-icos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxyicosanoyl-CoA --> H2O + trans-icos-2-enoyl-CoA 0.0003717106243194283 r_2171_REV B-hydroxyacyl-CoA dehydratase (trans-icos-2-enoyl-CoA) (reversible) 7.243203309692672e-06 prot_P40857 + H2O + trans-icos-2-enoyl-CoA --> 3-hydroxyicosanoyl-CoA 0.0 -r_2172 B-hydroxyacyl-CoA dehydratase (trans-docos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxydocosanoyl-CoA --> H2O + trans-docos-2-enoyl-CoA 0.0003717106244277723 +r_2172 B-hydroxyacyl-CoA dehydratase (trans-docos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxydocosanoyl-CoA --> H2O + trans-docos-2-enoyl-CoA 0.0003717106243194283 r_2172_REV B-hydroxyacyl-CoA dehydratase (trans-docos-2-enoyl-CoA) (reversible) 1.0640387527540613 prot_P40857 + H2O + trans-docos-2-enoyl-CoA --> 3-hydroxydocosanoyl-CoA 0.0 -r_2173 B-hydroxyacyl-CoA dehydratase (trans-tetracos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxytetracosanoyl-CoA --> H2O + trans-tetracos-2-enoyl-CoA 0.0003717106244277723 -r_2174 B-hydroxyacyl-CoA dehydratase (trans-hexacos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxyhexacosanoyl-CoA --> H2O + trans-hexacos-2-enoyl-CoA 0.0003717106244277723 +r_2173 B-hydroxyacyl-CoA dehydratase (trans-tetracos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxytetracosanoyl-CoA --> H2O + trans-tetracos-2-enoyl-CoA 0.0003717106243194283 +r_2174 B-hydroxyacyl-CoA dehydratase (trans-hexacos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxyhexacosanoyl-CoA --> H2O + trans-hexacos-2-enoyl-CoA 0.0003717106243194283 r_2174_REV B-hydroxyacyl-CoA dehydratase (trans-hexacos-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-hexacos-2-enoyl-CoA --> (S)-3-hydroxyhexacosanoyl-CoA 0.0 r_2175 trans-2-enoyl-CoA reductase (n-C14:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-tetradec-2-enoyl-CoA --> myristoyl-CoA + NADP(+) 0.00044172356996047285 -r_2176 trans-2-enoyl-CoA reductase (n-C16:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexadec-2-enoyl-CoA --> palmitoyl-CoA + NADP(+) 0.0006971172264636841 +r_2176 trans-2-enoyl-CoA reductase (n-C16:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexadec-2-enoyl-CoA --> palmitoyl-CoA + NADP(+) 0.0006971172333728206 r_2177 trans-2-enoyl-CoA reductase (n-C18:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-octadec-2-enoyl-CoA --> stearoyl-CoA + NADP(+) 0.0 -r_2178 trans-2-enoyl-CoA reductase (n-C20:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-icos-2-enoyl-CoA --> icosanoyl-CoA + NADP(+) 0.0003717106244277723 -r_2179 trans-2-enoyl-CoA reductase (n-C22:0CoA) 3.5110799393544463 prot_Q99190 + H+ + NADPH + trans-docos-2-enoyl-CoA --> docosanoyl-CoA + NADP(+) 0.0003717106244277723 -r_2180 trans-2-enoyl-CoA reductase (n-C24:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-tetracos-2-enoyl-CoA --> tetracosanoyl-CoA + NADP(+) 0.0003717106244277723 -r_2181 trans-2-enoyl-CoA reductase (n-C26:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexacos-2-enoyl-CoA --> NADP(+) + hexacosanoyl-CoA 0.0003717106244277723 -r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 13.846040131031963 prot_P21147 + H+ + palmitoyl-CoA + oxygen + NADH --> 2.0 H2O + palmitoleoyl-CoA(4-) + NAD 0.009608882822721758 -r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 46.3515873015873 prot_P21147 + H+ + stearoyl-CoA + oxygen + NADH --> 2.0 H2O + NAD + oleoyl-CoA 0.0030823586426598935 +r_2178 trans-2-enoyl-CoA reductase (n-C20:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-icos-2-enoyl-CoA --> icosanoyl-CoA + NADP(+) 0.0003717106243194283 +r_2179 trans-2-enoyl-CoA reductase (n-C22:0CoA) 3.5110799393544463 prot_Q99190 + H+ + NADPH + trans-docos-2-enoyl-CoA --> docosanoyl-CoA + NADP(+) 0.0003717106243194283 +r_2180 trans-2-enoyl-CoA reductase (n-C24:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-tetracos-2-enoyl-CoA --> tetracosanoyl-CoA + NADP(+) 0.0003717106243194283 +r_2181 trans-2-enoyl-CoA reductase (n-C26:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexacos-2-enoyl-CoA --> NADP(+) + hexacosanoyl-CoA 0.0003717106243194283 +r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 13.846040131031963 prot_P21147 + H+ + palmitoyl-CoA + oxygen + NADH --> 2.0 H2O + palmitoleoyl-CoA(4-) + NAD 0.0095238964371754 +r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 46.3515873015873 prot_P21147 + H+ + stearoyl-CoA + oxygen + NADH --> 2.0 H2O + NAD + oleoyl-CoA 0.003082358642659894 r_2184 octanoate (n-C8:0) transport octanoate --> octanoate 0.0 r_2184_REV octanoate (n-C8:0) transport (reversible) octanoate --> octanoate 0.0 r_2185 decanoate (n-C10:0) transport decanoate --> decanoate 0.0 -r_2185_REV decanoate (n-C10:0) transport (reversible) decanoate --> decanoate 0.002415660218418773 +r_2185_REV decanoate (n-C10:0) transport (reversible) decanoate --> decanoate 0.0024499794964130558 r_2186 laurate (n-C12:0) transport 0.6366271866276696 prot_P38225 + laurate --> laurate 0.0 r_2186_REV laurate (n-C12:0) transport (reversible) 0.6366271866276696 prot_P38225 + laurate --> laurate 0.0 r_2187 butyrate exchange butyrate --> 0.0 @@ -2593,7 +2593,7 @@ r_2191_REV hexanoate (n-C6:0) transport (reversible) 21.555294308917937 prot_P53 r_2192 octadecenoate (n-C18:1) transport 1.1688088711408016 prot_P38225 + oleate --> oleate 0.0 r_2192_REV octadecenoate (n-C18:1) transport (reversible) 1.1688088711408016 prot_P38225 + oleate --> oleate 0.0 r_2193 myristate exchange myristate --> 0.0 -r_2194 fatty-acid--CoA ligase (dodecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + laurate --> lauroyl-CoA + AMP + diphosphate 0.00044172356996047285 +r_2194 fatty-acid--CoA ligase (dodecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + laurate --> lauroyl-CoA + AMP + diphosphate 0.0 r_2194_REV fatty-acid--CoA ligase (dodecanoate), ER membrane (reversible) 4.27578504719294 prot_P30624 + lauroyl-CoA + AMP + diphosphate --> coenzyme A + ATP + laurate 0.0 r_2195_EXP_1 fatty-acid--CoA ligase (tetradecanoate), ER membrane 740.1053639846743 prot_P47912 + coenzyme A + ATP + myristate --> myristoyl-CoA + AMP + diphosphate 0.0 r_2195_EXP_2 fatty-acid--CoA ligase (tetradecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + myristate --> myristoyl-CoA + AMP + diphosphate 0.0 @@ -2605,7 +2605,7 @@ r_2196_REV_EXP_1 fatty-acid--CoA ligase (hexadecanoate), ER membrane (reversible r_2196_REV_EXP_2 fatty-acid--CoA ligase (hexadecanoate), ER membrane (reversible) 4.27578504719294 prot_P30624 + palmitoyl-CoA + AMP + diphosphate --> coenzyme A + ATP + palmitate 0.0 r_2197_EXP_1 fatty-acid--CoA ligase (hexadecenoate), ER membrane 789.6458183044103 prot_P47912 + coenzyme A + ATP + palmitoleate --> palmitoleoyl-CoA(4-) + AMP + diphosphate 0.0 r_2197_EXP_2 fatty-acid--CoA ligase (hexadecenoate), ER membrane 795.767420607649 prot_P30624 + coenzyme A + ATP + palmitoleate --> palmitoleoyl-CoA(4-) + AMP + diphosphate 0.0 -r_2197_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), ER membrane (reversible) 3.189962202455639 prot_P47912 + palmitoleoyl-CoA(4-) + AMP + diphosphate --> coenzyme A + ATP + palmitoleate 4.85703771638254e-10 +r_2197_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), ER membrane (reversible) 3.189962202455639 prot_P47912 + palmitoleoyl-CoA(4-) + AMP + diphosphate --> coenzyme A + ATP + palmitoleate -1.117289749032978e-09 r_2197_REV_EXP_2 fatty-acid--CoA ligase (hexadecenoate), ER membrane (reversible) 4.583272040765874 prot_P30624 + palmitoleoyl-CoA(4-) + AMP + diphosphate --> coenzyme A + ATP + palmitoleate 0.0 r_2198_EXP_1 fatty-acid--CoA ligase (octadecanoate), ER membrane 740.1053639846743 prot_P47912 + coenzyme A + ATP + stearate --> stearoyl-CoA + AMP + diphosphate 0.0 r_2198_EXP_2 fatty-acid--CoA ligase (octadecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + stearate --> stearoyl-CoA + AMP + diphosphate 0.0 @@ -2615,9 +2615,9 @@ r_2199_EXP_1 fatty-acid--CoA ligase (octadecenoate), ER membrane 646.43697171813 r_2199_EXP_2 fatty-acid--CoA ligase (octadecenoate), ER membrane 651.4483704531559 prot_P30624 + coenzyme A + ATP + oleate --> oleoyl-CoA + AMP + diphosphate 0.0 r_2199_REV_EXP_1 fatty-acid--CoA ligase (octadecenoate), ER membrane (reversible) 3.15048984865542 prot_P47912 + oleoyl-CoA + AMP + diphosphate --> coenzyme A + ATP + oleate 0.0 r_2199_REV_EXP_2 fatty-acid--CoA ligase (octadecenoate), ER membrane (reversible) 4.477103447320649 prot_P30624 + oleoyl-CoA + AMP + diphosphate --> coenzyme A + ATP + oleate 0.0 -r_2200 fatty-acid--CoA ligase (dodecanoate), lipid particle 745.8429118773946 prot_P30624 + coenzyme A + ATP + laurate --> diphosphate + AMP + lauroyl-CoA 0.0 +r_2200 fatty-acid--CoA ligase (dodecanoate), lipid particle 745.8429118773946 prot_P30624 + coenzyme A + ATP + laurate --> diphosphate + AMP + lauroyl-CoA 0.00044172356996047285 r_2200_REV fatty-acid--CoA ligase (dodecanoate), lipid particle (reversible) 4.27578504719294 prot_P30624 + diphosphate + AMP + lauroyl-CoA --> coenzyme A + ATP + laurate 0.0 -r_2201_EXP_1 fatty-acid--CoA ligase (tetradecanoate), lipid particle 740.1053639846743 prot_P47912 + coenzyme A + ATP + myristate --> diphosphate + AMP + myristoyl-CoA 0.00025539365650321597 +r_2201_EXP_1 fatty-acid--CoA ligase (tetradecanoate), lipid particle 740.1053639846743 prot_P47912 + coenzyme A + ATP + myristate --> diphosphate + AMP + myristoyl-CoA 0.00025539366341234895 r_2201_EXP_2 fatty-acid--CoA ligase (tetradecanoate), lipid particle 745.8429118773946 prot_P30624 + coenzyme A + ATP + myristate --> diphosphate + AMP + myristoyl-CoA 0.0 r_2201_REV_EXP_1 fatty-acid--CoA ligase (tetradecanoate), lipid particle (reversible) 3.0403097470779796 prot_P47912 + diphosphate + AMP + myristoyl-CoA --> coenzyme A + ATP + myristate 0.0 r_2201_REV_EXP_2 fatty-acid--CoA ligase (tetradecanoate), lipid particle (reversible) 4.27578504719294 prot_P30624 + diphosphate + AMP + myristoyl-CoA --> coenzyme A + ATP + myristate 0.0 @@ -2666,13 +2666,13 @@ r_2218_REV fatty-acid--CoA ligase (cerotic acid), lipid particle (reversible) 1. r_2219 fatty acyl-CoA transport via ABC system (C12:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + lauroyl-CoA --> ADP + H+ + lauroyl-CoA + phosphate 0.0 r_2220 fatty acyl-CoA transport via ABC system (C14:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + myristoyl-CoA --> ADP + H+ + myristoyl-CoA + phosphate 0.0 r_2221 fatty acyl-CoA transport via ABC system (C16:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + palmitoyl-CoA --> ADP + H+ + palmitoyl-CoA + phosphate 0.0 -r_2222 fatty acyl-CoA transport via ABC system (C16:1) 102.59519988879609 prot_P34230 + 105.65744361835995 prot_P41909 + ATP + H2O + palmitoleoyl-CoA(4-) --> ADP + H+ + phosphate + palmitoleoyl-CoA(4-) 0.00028144707955366557 -r_2223 fatty acyl-CoA transport via ABC system (C18:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + stearoyl-CoA --> ADP + H+ + phosphate + stearoyl-CoA 0.002741066821639421 +r_2222 fatty acyl-CoA transport via ABC system (C16:1) 102.59519988879609 prot_P34230 + 105.65744361835995 prot_P41909 + ATP + H2O + palmitoleoyl-CoA(4-) --> ADP + H+ + phosphate + palmitoleoyl-CoA(4-) 0.00019646069400727024 +r_2223 fatty acyl-CoA transport via ABC system (C18:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + stearoyl-CoA --> ADP + H+ + phosphate + stearoyl-CoA 0.0028154299084836706 r_2224 fatty acyl-CoA transport via ABC system (C18:1) 102.6162244595619 prot_P34230 + 105.67909572686696 prot_P41909 + ATP + H2O + oleoyl-CoA --> ADP + H+ + oleoyl-CoA + phosphate 0.0 r_2225 fatty acyl-CoA transport via ABC system (C20:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + icosanoyl-CoA --> ADP + H+ + phosphate + icosanoyl-CoA 0.0 r_2226 fatty acyl-CoA transport via ABC system (C22:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + docosanoyl-CoA --> ADP + H+ + phosphate + docosanoyl-CoA 0.0 r_2227 fatty acyl-CoA transport via ABC system (C24:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + tetracosanoyl-CoA --> ADP + H+ + phosphate + tetracosanoyl-CoA 0.0 -r_2228 fatty acyl-CoA transport via ABC system (C26:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + hexacosanoyl-CoA --> ADP + H+ + hexacosanoyl-CoA + phosphate 0.0003717106244277723 +r_2228 fatty acyl-CoA transport via ABC system (C26:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + hexacosanoyl-CoA --> ADP + H+ + hexacosanoyl-CoA + phosphate 0.0003717106243194283 r_2229 butyrate (n-C4:0) transport, cytoplasm-peroxisome butyrate --> butyrate 0.0 r_2229_REV butyrate (n-C4:0) transport, cytoplasm-peroxisome (reversible) butyrate --> butyrate 0.0 r_2230 hexanoate (n-C6:0) transport, cytoplasm-peroxisome hexanoate --> hexanoate 0.0 @@ -2683,66 +2683,66 @@ r_2232 peroxisomal acyl-CoA thioesterase (4:0) 0.12566955088586731 prot_P41903 + r_2233 peroxisomal acyl-CoA thioesterase (6:0) 931.9444444444443 prot_P41903 + H2O + hexanoyl-CoA --> coenzyme A + 5.0 H+ + hexanoate 0.0 r_2234 peroxisomal acyl-CoA thioesterase (16:1) 0.12566955088586731 prot_P41903 + H2O + palmitoleoyl-CoA(4-) --> coenzyme A + H+ + palmitoleate 0.0 r_2235 peroxisomal acyl-CoA thioesterase (18:1) 0.12566955088586731 prot_P41903 + H2O + oleoyl-CoA --> coenzyme A + H+ + oleate 0.0 -r_2236 acyl-CoA oxidase (butanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + butanoyl-CoA --> hydrogen peroxide + trans-but-2-enoyl-CoA 0.00028144707955366557 -r_2237 acyl-CoA oxidase (hexanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + hexanoyl-CoA --> hydrogen peroxide + trans-hex-2-enoyl-CoA 0.00028144707955366557 -r_2238 acyl-CoA oxidase (octanoyl-CoA) 6.727665706051873 prot_P13711 + octanoyl-CoA + oxygen --> hydrogen peroxide + trans-oct-2-enoyl-CoA 0.00028144707955366557 -r_2239 acyl-CoA oxidase (icosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + icosanoyl-CoA --> hydrogen peroxide + trans-icos-2-enoyl-CoA 0.0003717106244277723 -r_2240 acyl-CoA oxidase (docosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + docosanoyl-CoA --> hydrogen peroxide + trans-docos-2-enoyl-CoA 0.0003717106244277723 -r_2241 acyl-CoA oxidase (tetracosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + tetracosanoyl-CoA --> hydrogen peroxide + trans-tetracos-2-enoyl-CoA 0.0003717106244277723 -r_2242 acyl-CoA oxidase (palmitoleoyl-CoA) 2.7176949941792783 prot_P13711 + 4.0 H+ + oxygen + palmitoleoyl-CoA(4-) --> hydrogen peroxide + trans-2,cis-9-hexadecadienoyl-CoA 0.00028144707955366557 -r_2243 acyl-CoA oxidase (cis-tetradec-7-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-tetradec-7-enoyl-CoA --> hydrogen peroxide + trans-2,cis-7-tetradecadienoyl-CoA 0.00028144707955366557 -r_2244 acyl-CoA oxidase (cis-dodec-5-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-dodec-5-enoyl-CoA --> hydrogen peroxide + trans-2,cis-5-dodecadienoyl-CoA 0.00028144707955366557 +r_2236 acyl-CoA oxidase (butanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + butanoyl-CoA --> hydrogen peroxide + trans-but-2-enoyl-CoA 0.0002365045025291035 +r_2237 acyl-CoA oxidase (hexanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + hexanoyl-CoA --> hydrogen peroxide + trans-hex-2-enoyl-CoA 0.0002365045025291035 +r_2238 acyl-CoA oxidase (octanoyl-CoA) 6.727665706051873 prot_P13711 + octanoyl-CoA + oxygen --> hydrogen peroxide + trans-oct-2-enoyl-CoA 0.0002365045025291035 +r_2239 acyl-CoA oxidase (icosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + icosanoyl-CoA --> hydrogen peroxide + trans-icos-2-enoyl-CoA 0.0003717106243194283 +r_2240 acyl-CoA oxidase (docosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + docosanoyl-CoA --> hydrogen peroxide + trans-docos-2-enoyl-CoA 0.0003717106243194283 +r_2241 acyl-CoA oxidase (tetracosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + tetracosanoyl-CoA --> hydrogen peroxide + trans-tetracos-2-enoyl-CoA 0.0003717106243194283 +r_2242 acyl-CoA oxidase (palmitoleoyl-CoA) 2.7176949941792783 prot_P13711 + 4.0 H+ + oxygen + palmitoleoyl-CoA(4-) --> hydrogen peroxide + trans-2,cis-9-hexadecadienoyl-CoA 0.00019646069400727024 +r_2243 acyl-CoA oxidase (cis-tetradec-7-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-tetradec-7-enoyl-CoA --> hydrogen peroxide + trans-2,cis-7-tetradecadienoyl-CoA 0.00019646069400727024 +r_2244 acyl-CoA oxidase (cis-dodec-5-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-dodec-5-enoyl-CoA --> hydrogen peroxide + trans-2,cis-5-dodecadienoyl-CoA 0.00019646069400727024 r_2245 acyl-CoA oxidase (oleoyl-CoA) 2.7176949941792783 prot_P13711 + oleoyl-CoA + oxygen --> hydrogen peroxide + trans-2,cis-9-octadecadienoyl-CoA 0.0 r_2246 acyl-CoA oxidase (cis-hexadec-7-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-hexadec-7-enoyl-CoA --> hydrogen peroxide + trans-2,cis-7-hexadecadienoyl-CoA 0.0 r_2247 acyl-CoA oxidase (cis-tetradec-5-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-tetradec-5-enoyl-CoA --> hydrogen peroxide + trans-2,cis-5-tetradecadienoyl-CoA 0.0 -r_2248 2-enoyl-CoA hydratase (3-hydroxydecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dec-2-enoyl-CoA --> (R)-3-hydroxydecanoyl-CoA 0.00028144707955366557 -r_2249 2-enoyl-CoA hydratase (3-hydroxydodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dodec-2-enoyl-CoA --> (R)-3-hydroxylauroyl-CoA 0.002415660218418773 -r_2250 2-enoyl-CoA hydratase (3-hydroxytetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetradec-2-enoyl-CoA --> (S)-3-hydroxytetradecanoyl-CoA 0.002857383788379246 -r_2251 2-enoyl-CoA hydratase (3-hydroxyhexadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + hexadec-2-enoyl-CoA --> (S)-3-hydroxypalmitoyl-CoA 0.003112777444882465 -r_2252 2-enoyl-CoA hydratase (3-hydroxyoctadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-octadec-2-enoyl-CoA --> 3-hydroxyoctadecanoyl-CoA 0.003112777446067193 -r_2253 2-enoyl-CoA hydratase (3-hydroxyhexacosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hexacos-2-enoyl-CoA --> (S)-3-hydroxyhexacosanoyl-CoA 0.0003717106244277723 -r_2254 2-enoyl-CoA hydratase (3-hydroxybutanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-but-2-enoyl-CoA --> (R)-3-hydroxybutanoyl-CoA 0.00028144707955366557 -r_2255 2-enoyl-CoA hydratase (3-hydroxyhexanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hex-2-enoyl-CoA --> (R)-3-hydroxyhexanoyl-CoA 0.00028144707955366557 -r_2256 2-enoyl-CoA hydratase (3-hydroxyoctanoyl-CoA) 0.07066365979381443 prot_Q02207 + 4.0 H+ + H2O + trans-oct-2-enoyl-CoA --> (R)-3-hydroxyoctanoyl-CoA 0.00028144707955366557 -r_2257 2-enoyl-CoA hydratase (3-hydroxyicosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-icos-2-enoyl-CoA --> (R)-3-hydroxyicosanoyl-CoA 0.0003717106244277723 -r_2258 2-enoyl-CoA hydratase (3-hydroxydocosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-docos-2-enoyl-CoA --> (R)-3-hydroxydocosanoyl-CoA 0.0003717106244277723 -r_2259 2-enoyl-CoA hydratase (3-hydroxytetracosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetracos-2-enoyl-CoA --> (R)-3-hydroxytetracosanoyl-CoA 0.0003717106244277723 -r_2260 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-9-hexadecadienoyl-CoA --> (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA 0.00028144707955366557 -r_2261 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-7-tetradecadienoyl-CoA --> (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA 0.00028144707955366557 -r_2262 2-enoyl-CoA hydratase (3-hydroxy-cis-dodec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-5-dodecadienoyl-CoA --> (R)-3-hydroxy-cis-dodec-5-enoyl-CoA 0.00028144707955366557 +r_2248 2-enoyl-CoA hydratase (3-hydroxydecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dec-2-enoyl-CoA --> (R)-3-hydroxydecanoyl-CoA 0.0002365045025291035 +r_2249 2-enoyl-CoA hydratase (3-hydroxydodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dodec-2-enoyl-CoA --> (R)-3-hydroxylauroyl-CoA 0.002490023304934889 +r_2250 2-enoyl-CoA hydratase (3-hydroxytetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetradec-2-enoyl-CoA --> (S)-3-hydroxytetradecanoyl-CoA 0.0029317468748953617 +r_2251 2-enoyl-CoA hydratase (3-hydroxyhexadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + hexadec-2-enoyl-CoA --> (S)-3-hydroxypalmitoyl-CoA 0.003187140538307717 +r_2252 2-enoyl-CoA hydratase (3-hydroxyoctadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-octadec-2-enoyl-CoA --> 3-hydroxyoctadecanoyl-CoA 0.003187140532803099 +r_2253 2-enoyl-CoA hydratase (3-hydroxyhexacosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hexacos-2-enoyl-CoA --> (S)-3-hydroxyhexacosanoyl-CoA 0.0003717106243194283 +r_2254 2-enoyl-CoA hydratase (3-hydroxybutanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-but-2-enoyl-CoA --> (R)-3-hydroxybutanoyl-CoA 0.0002365045025291035 +r_2255 2-enoyl-CoA hydratase (3-hydroxyhexanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hex-2-enoyl-CoA --> (R)-3-hydroxyhexanoyl-CoA 0.0002365045025291035 +r_2256 2-enoyl-CoA hydratase (3-hydroxyoctanoyl-CoA) 0.07066365979381443 prot_Q02207 + 4.0 H+ + H2O + trans-oct-2-enoyl-CoA --> (R)-3-hydroxyoctanoyl-CoA 0.0002365045025291035 +r_2257 2-enoyl-CoA hydratase (3-hydroxyicosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-icos-2-enoyl-CoA --> (R)-3-hydroxyicosanoyl-CoA 0.0003717106243194283 +r_2258 2-enoyl-CoA hydratase (3-hydroxydocosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-docos-2-enoyl-CoA --> (R)-3-hydroxydocosanoyl-CoA 0.0003717106243194283 +r_2259 2-enoyl-CoA hydratase (3-hydroxytetracosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetracos-2-enoyl-CoA --> (R)-3-hydroxytetracosanoyl-CoA 0.0003717106243194283 +r_2260 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-9-hexadecadienoyl-CoA --> (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA 0.00019646069400727024 +r_2261 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-7-tetradecadienoyl-CoA --> (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA 0.00019646069400727024 +r_2262 2-enoyl-CoA hydratase (3-hydroxy-cis-dodec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-5-dodecadienoyl-CoA --> (R)-3-hydroxy-cis-dodec-5-enoyl-CoA 0.00019646069400727024 r_2263 2-enoyl-CoA hydratase (3-hydroxy-cis-octadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + 4.0 H+ + H2O + trans-2,cis-9-octadecadienoyl-CoA --> (R)-3-hydroxy-cis-octadec-9-enoyl-CoA 0.0 r_2264 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-7-hexadecadienoyl-CoA --> (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA 0.0 r_2265 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-5-tetradecadienoyl-CoA --> (R)-3-hydroxy-cis-tetradec-5-enoyl-CoA 0.0 -r_2266 3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxydecanoyl-CoA + NAD --> 3-oxodecanoyl-CoA + H+ + NADH 0.00028144707955366557 -r_2267 3-hydroxyacyl-CoA dehydrogenase (3-oxododecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxylauroyl-CoA + NAD --> 3-oxolauroyl-CoA + H+ + NADH 0.002415660218418773 -r_2268 3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxypalmitoyl-CoA + NAD --> 3-oxopalmitoyl-CoA + H+ + NADH 0.003112777444882465 -r_2269 3-hydroxyacyl-CoA dehydrogenase (3-oxooctadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + 3-hydroxyoctadecanoyl-CoA + NAD --> 3-oxooctadecanoyl-CoA + H+ + NADH 0.003112777446067193 -r_2270 3-hydroxyacyl-CoA dehydrogenase (3-oxohexacosanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxyhexacosanoyl-CoA + NAD --> 3-oxohexacosanoyl-CoA + H+ + NADH 0.0003717106244277723 -r_2271 3-hydroxyacyl-CoA dehydrogenase (3-oxobutanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxybutanoyl-CoA --> H+ + NADH + acetoacetyl-CoA 0.00028144707955366557 -r_2272 3-hydroxyacyl-CoA dehydrogenase (3-oxohexanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyhexanoyl-CoA --> H+ + NADH + 3-oxohexanoyl-CoA 0.00028144707955366557 -r_2273 3-hydroxyacyl-CoA dehydrogenase (3-oxooctanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyoctanoyl-CoA --> H+ + NADH + 3-oxooctanoyl-CoA 0.00028144707955366557 -r_2274 3-hydroxyacyl-CoA dehydrogenase (3-oxoicosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyicosanoyl-CoA --> H+ + NADH + 3-oxoicosanoyl-CoA 0.0003717106244277723 -r_2275 3-hydroxyacyl-CoA dehydrogenase (3-oxodocosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxydocosanoyl-CoA --> H+ + NADH + 3-oxodocosanoyl-CoA 0.0003717106244277723 -r_2276 3-hydroxyacyl-CoA dehydrogenase (3-oxotetracosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxytetracosanoyl-CoA --> H+ + NADH + 3-oxotetracosanoyl-CoA 0.0003717106244277723 -r_2277 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA --> H+ + NADH + 3-oxo-cis-hexadec-9-enoyl-CoA 0.00028144707955366557 -r_2278 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA --> H+ + NADH + 3-oxo-cis-tetradec-7-enoyl-CoA 0.00028144707955366557 -r_2279 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-dodec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-dodec-5-enoyl-CoA --> H+ + NADH + 3-oxo-cis-dodec-5-enoyl-CoA 0.00028144707955366557 +r_2266 3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxydecanoyl-CoA + NAD --> 3-oxodecanoyl-CoA + H+ + NADH 0.0002365045025291035 +r_2267 3-hydroxyacyl-CoA dehydrogenase (3-oxododecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxylauroyl-CoA + NAD --> 3-oxolauroyl-CoA + H+ + NADH 0.002490023304934889 +r_2268 3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxypalmitoyl-CoA + NAD --> 3-oxopalmitoyl-CoA + H+ + NADH 0.003187140538307717 +r_2269 3-hydroxyacyl-CoA dehydrogenase (3-oxooctadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + 3-hydroxyoctadecanoyl-CoA + NAD --> 3-oxooctadecanoyl-CoA + H+ + NADH 0.003187140532803099 +r_2270 3-hydroxyacyl-CoA dehydrogenase (3-oxohexacosanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxyhexacosanoyl-CoA + NAD --> 3-oxohexacosanoyl-CoA + H+ + NADH 0.0003717106243194283 +r_2271 3-hydroxyacyl-CoA dehydrogenase (3-oxobutanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxybutanoyl-CoA --> H+ + NADH + acetoacetyl-CoA 0.0002365045025291035 +r_2272 3-hydroxyacyl-CoA dehydrogenase (3-oxohexanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyhexanoyl-CoA --> H+ + NADH + 3-oxohexanoyl-CoA 0.0002365045025291035 +r_2273 3-hydroxyacyl-CoA dehydrogenase (3-oxooctanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyoctanoyl-CoA --> H+ + NADH + 3-oxooctanoyl-CoA 0.0002365045025291035 +r_2274 3-hydroxyacyl-CoA dehydrogenase (3-oxoicosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyicosanoyl-CoA --> H+ + NADH + 3-oxoicosanoyl-CoA 0.0003717106243194283 +r_2275 3-hydroxyacyl-CoA dehydrogenase (3-oxodocosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxydocosanoyl-CoA --> H+ + NADH + 3-oxodocosanoyl-CoA 0.0003717106243194283 +r_2276 3-hydroxyacyl-CoA dehydrogenase (3-oxotetracosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxytetracosanoyl-CoA --> H+ + NADH + 3-oxotetracosanoyl-CoA 0.0003717106243194283 +r_2277 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA --> H+ + NADH + 3-oxo-cis-hexadec-9-enoyl-CoA 0.00019646069400727024 +r_2278 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA --> H+ + NADH + 3-oxo-cis-tetradec-7-enoyl-CoA 0.00019646069400727024 +r_2279 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-dodec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-dodec-5-enoyl-CoA --> H+ + NADH + 3-oxo-cis-dodec-5-enoyl-CoA 0.00019646069400727024 r_2280 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-octadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-octadec-9-enoyl-CoA --> H+ + NADH + 3-oxo-cis-octadec-9-enoyl-CoA 0.0 r_2281 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA --> H+ + NADH + 3-oxo-cis-hexadec-7-enoyl-CoA 0.0 r_2282 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-tetradec-5-enoyl-CoA --> H+ + NADH + 3-oxo-cis-tetradec-5-enoyl-CoA 0.0 -r_2283 acetyl-CoA C-acyltransferase (acetyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + acetoacetyl-CoA --> 2.0 acetyl-CoA 0.00028144707955366557 -r_2284 acetyl-CoA C-acyltransferase (butanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxohexanoyl-CoA --> acetyl-CoA + 4.0 H+ + butanoyl-CoA 0.00028144707955366557 -r_2285 acetyl-CoA C-acyltransferase (hexanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxooctanoyl-CoA --> acetyl-CoA + hexanoyl-CoA 0.00028144707955366557 -r_2286 acetyl-CoA C-acyltransferase (stearoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxoicosanoyl-CoA --> acetyl-CoA + stearoyl-CoA 0.0003717106244277723 -r_2287 acetyl-CoA C-acyltransferase (icosanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxodocosanoyl-CoA --> acetyl-CoA + icosanoyl-CoA 0.0003717106244277723 -r_2288 acetyl-CoA C-acyltransferase (docosanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxotetracosanoyl-CoA --> acetyl-CoA + docosanoyl-CoA 0.0003717106244277723 -r_2289 acetyl-CoA C-acyltransferase (cis-tetradec-7-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-hexadec-9-enoyl-CoA --> acetyl-CoA + cis-tetradec-7-enoyl-CoA 0.00028144707955366557 -r_2290 acetyl-CoA C-acyltransferase (cis-dodec-5-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-tetradec-7-enoyl-CoA --> acetyl-CoA + cis-dodec-5-enoyl-CoA 0.00028144707955366557 -r_2291 acetyl-CoA C-acyltransferase (cis-dec-3-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-dodec-5-enoyl-CoA --> acetyl-CoA + cis-dec-3-enoyl-CoA 0.00028144707955366557 +r_2283 acetyl-CoA C-acyltransferase (acetyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + acetoacetyl-CoA --> 2.0 acetyl-CoA 0.0002365045025291035 +r_2284 acetyl-CoA C-acyltransferase (butanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxohexanoyl-CoA --> acetyl-CoA + 4.0 H+ + butanoyl-CoA 0.0002365045025291035 +r_2285 acetyl-CoA C-acyltransferase (hexanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxooctanoyl-CoA --> acetyl-CoA + hexanoyl-CoA 0.0002365045025291035 +r_2286 acetyl-CoA C-acyltransferase (stearoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxoicosanoyl-CoA --> acetyl-CoA + stearoyl-CoA 0.0003717106243194283 +r_2287 acetyl-CoA C-acyltransferase (icosanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxodocosanoyl-CoA --> acetyl-CoA + icosanoyl-CoA 0.0003717106243194283 +r_2288 acetyl-CoA C-acyltransferase (docosanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxotetracosanoyl-CoA --> acetyl-CoA + docosanoyl-CoA 0.0003717106243194283 +r_2289 acetyl-CoA C-acyltransferase (cis-tetradec-7-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-hexadec-9-enoyl-CoA --> acetyl-CoA + cis-tetradec-7-enoyl-CoA 0.00019646069400727024 +r_2290 acetyl-CoA C-acyltransferase (cis-dodec-5-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-tetradec-7-enoyl-CoA --> acetyl-CoA + cis-dodec-5-enoyl-CoA 0.00019646069400727024 +r_2291 acetyl-CoA C-acyltransferase (cis-dec-3-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-dodec-5-enoyl-CoA --> acetyl-CoA + cis-dec-3-enoyl-CoA 0.00019646069400727024 r_2292 acetyl-CoA C-acyltransferase (cis-hexadec-7-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-octadec-9-enoyl-CoA --> acetyl-CoA + cis-hexadec-7-enoyl-CoA 0.0 r_2293 acetyl-CoA C-acyltransferase (cis-tetradec-5-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-hexadec-7-enoyl-CoA --> acetyl-CoA + cis-tetradec-5-enoyl-CoA 0.0 r_2294 acetyl-CoA C-acyltransferase (cis-dodec-3-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-tetradec-5-enoyl-CoA --> acetyl-CoA + cis-dodec-3-enoyl-CoA 0.0 -r_2295 delta3,delta2-enoyl-CoA isomerase (cis-dec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + cis-dec-3-enoyl-CoA --> 4.0 H+ + trans-dec-2-enoyl-CoA 0.00028144707955366557 +r_2295 delta3,delta2-enoyl-CoA isomerase (cis-dec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + cis-dec-3-enoyl-CoA --> 4.0 H+ + trans-dec-2-enoyl-CoA 0.00019646069400727024 r_2296 delta3,delta2-enoyl-CoA isomerase (trans-2,cis-5-dodecadienoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-2,cis-5-dodecadienoyl-CoA --> trans-3,cis-5-dodecadienoyl-CoA 0.0 r_2297 delta3,delta2-enoyl-CoA isomerase (trans-dodec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-dodec-3-enoyl-CoA --> 4.0 H+ + trans-dodec-2-enoyl-CoA 0.0 r_2298 delta3,delta2-enoyl-CoA isomerase (cis-dodec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + cis-dodec-3-enoyl-CoA --> 4.0 H+ + trans-dodec-2-enoyl-CoA 0.0 @@ -2752,11 +2752,11 @@ r_2301 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-dodecadienoyl- r_2302 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-tetradecadienoyl-CoA) 0.0026092013888888888 prot_Q08558 + trans-3,cis-5-tetradecadienoyl-CoA --> trans-2,trans-4-tetradecadienoyl-CoA 0.0 r_2303 2,4-dienoyl-CoA reductase (trans-2,trans-4-dodecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-dodecadienoyl-CoA --> NADP(+) + trans-dodec-3-enoyl-CoA 0.0 r_2304 2,4-dienoyl-CoA reductase (trans-2,trans-4-tetradecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-tetradecadienoyl-CoA --> NADP(+) + trans-tetradec-3-enoyl-CoA 0.0 -r_2305 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 1.5535005162214965 +r_2305 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 1.4937695999999998 r_2305_REV cis-aconitate(3-) to isocitrate (reversible) 0.16582750582750583 prot_P19414 + isocitrate --> cis-aconitate + H2O 0.0 -r_2308_EXP_1 glycerol-3-phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0031532487209100383 +r_2308_EXP_1 glycerol-3-phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0031532487275993844 r_2308_EXP_2 glycerol-3-phosphate acyltransferase (16:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0 -r_2309_EXP_1 glycerol-3-phosphate acyltransferase (16:1), ER membrane 124.56838874829987 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0035240142405468236 +r_2309_EXP_1 glycerol-3-phosphate acyltransferase (16:1), ER membrane 124.56838874829987 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0035240142338308455 r_2309_EXP_2 glycerol-3-phosphate acyltransferase (16:1), ER membrane 121.5898765007065 prot_P36148 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0 r_2310 glycerol-3-phosphate acyltransferase (18:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + stearoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0 r_2311 glycerol-3-phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 0.0 @@ -2768,7 +2768,7 @@ r_2314 dihydroxyacetone phosphate acyltransferase (18:0), ER membrane 97.6248832 r_2315 dihydroxyacetone phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (18:1) 0.0 r_2316 glycerol-3-phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0 r_2317 glycerol-3-phosphate acyltransferase (16:1), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoleoyl-CoA(4-) --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0 -r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + stearoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.00027766980278451256 +r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + stearoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0002776698027845441 r_2319 glycerol-3-phosphate acyltransferase (18:1), lipid particle 106.58129459734965 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + oleoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 0.0 r_2320 dihydroxyacetone phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + dihydroxyacetone phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + acylglycerone phosphate (16:0) 0.0 r_2321 dihydroxyacetone phosphate acyltransferase (16:1), lipid particle 97.624883286648 prot_P36148 + dihydroxyacetone phosphate + 2.0 H+ + palmitoleoyl-CoA(4-) --> coenzyme A + acylglycerone phosphate (16:1) 0.0 @@ -2782,11 +2782,11 @@ r_2328 acyl dhap reductase (16:0), lipid particle 0.09115 prot_P40471 + H+ + acy r_2329 acyl dhap reductase (16:1), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (16:1) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (16:1) + NADP(+) 0.0 r_2330 acyl dhap reductase (18:0), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (18:0) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (18:0) + NADP(+) 0.0 r_2331 acyl dhap reductase (18:1), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (18:1) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (18:1) + NADP(+) 0.0 -r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-16:1) 0.002394439484361775 -r_2333_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0005354424594813091 +r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-16:1) 0.002394439523657025 +r_2333_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0005354424268754053 r_2333_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.00022336677706695398 -r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 113.27321041547852 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-16:1) 0.002507587857235077 -r_2335_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.001016426383311754 +r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 113.27321041547852 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-16:1) 0.0025075878179132184 +r_2335_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.001016426415917627 r_2335_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 r_2336 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-16:1) 0.0 r_2337_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 @@ -2802,7 +2802,7 @@ r_2341_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), li r_2341_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 r_2342_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 r_2342_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 -r_2342_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.00027766980278451256 +r_2342_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0002776698027845441 r_2343_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2343_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2343_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 @@ -2822,12 +2822,12 @@ r_2356 PA phosphatase (1-18:0, 2-16:1), vacuolar membrane 0.0963012769674609 pro r_2357 PA phosphatase (1-18:0, 2-18:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0 r_2358 PA phosphatase (1-18:1, 2-16:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:1, 2-16:1) --> phosphate + diglyceride (1-18:1, 2-16:1) + 2.0 H+ 0.0 r_2359 PA phosphatase (1-18:1, 2-18:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:1, 2-18:1) --> phosphate + diglyceride (1-18:1, 2-18:1) + 2.0 H+ 0.0 -r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + phosphatidate (1-16:0, 2-16:1) + H2O --> phosphate + diglyceride (1-16:0, 2-16:1) + 2.0 H+ 0.002394439425894307 +r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + phosphatidate (1-16:0, 2-16:1) + H2O --> phosphate + diglyceride (1-16:0, 2-16:1) + 2.0 H+ 0.002394439523657025 r_2361 PA phosphatase (1-16:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:0, 2-18:1) --> phosphate + diglyceride (1-16:0, 2-18:1) + 2.0 H+ 0.0 r_2362 PA phosphatase (1-16:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-16:1) --> phosphate + diglyceride (1-16:1, 2-16:1) + 2.0 H+ 0.0 -r_2363 PA phosphatase (1-16:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-18:1) --> phosphate + diglyceride (1-16:1, 2-18:1) + 2.0 H+ 0.0007565683704506696 +r_2363 PA phosphatase (1-16:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-18:1) --> phosphate + diglyceride (1-16:1, 2-18:1) + 2.0 H+ 0.0007565683703719278 r_2364 PA phosphatase (1-18:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-16:1) --> phosphate + diglyceride (1-18:0, 2-16:1) + 2.0 H+ 0.0 -r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.00027766980278451256 +r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0002776698027845441 r_2366 PA phosphatase (1-18:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:1, 2-16:1) --> phosphate + diglyceride (1-18:1, 2-16:1) + 2.0 H+ 0.0 r_2367 PA phosphatase (1-18:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:1, 2-18:1) --> phosphate + diglyceride (1-18:1, 2-18:1) + 2.0 H+ 0.0 r_2368_EXP_1 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:0), ER membrane 67.08130559354814 prot_P25628 + palmitoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-16:0) 0.0 @@ -2859,10 +2859,10 @@ r_2376_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:1), ER membran r_2376_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-16:1) 0.0 r_2377_EXP_1 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 r_2377_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 -r_2377_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 +r_2377_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0005472083134696547 r_2378_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_2378_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 -r_2378_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.000864516242872001 +r_2378_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.00031730953913846043 r_2379_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2379_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2379_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 @@ -2886,7 +2886,7 @@ r_2385_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membran r_2385_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 r_2386_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 67.08130559354814 prot_P25628 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 r_2386_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 20.519322196722364 prot_P53629 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 -r_2386_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0005189749331325122 +r_2386_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 r_2387_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 67.08130559354814 prot_P25628 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2387_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 20.519322196722364 prot_P53629 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2387_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 @@ -2944,7 +2944,7 @@ r_2414 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:1), lipid particle 1 r_2415 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-16:1) 0.0 r_2416 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-18:0) 0.0 r_2417 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 -r_2418 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 +r_2418 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0005189749331324809 r_2419 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2420 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-18:0, 2-16:1) --> coenzyme A + triglyceride (1-18:0, 2-16:1, 3-18:0) 0.0 r_2421 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-18:0, 2-18:1) --> coenzyme A + triglyceride (1-18:0, 2-18:1, 3-18:0) 0.0 @@ -2958,17 +2958,17 @@ r_2428 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:1), lipid particle 1 r_2429 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:0, 2-18:1) --> coenzyme A + triglyceride (1-18:0, 2-18:1, 3-18:1) 0.0 r_2430 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:1, 2-16:1) --> coenzyme A + triglyceride (1-18:1, 2-16:1, 3-18:1) 0.0 r_2431 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-18:1) 0.0 -r_2432 CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) 5.846746774310264e-11 +r_2432 CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) 0.0 r_2432_REV CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) --> H+ + phosphatidate (1-16:0, 2-16:1) + CTP 0.0 -r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0018202639565357203 +r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0018202640151935097 r_2433_REV CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) --> H+ + phosphatidate (1-16:1, 2-16:1) + CTP 0.0 r_2434 CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) 0.0 r_2434_REV CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) --> H+ + phosphatidate (1-18:0, 2-16:1) + CTP 0.0 -r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.0034727008628694335 +r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.0034727008625737923 r_2435_REV CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) --> H+ + phosphatidate (1-18:1, 2-16:1) + CTP 0.0 -r_2436 CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0007588092365482631 +r_2436 CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0007588092039423592 r_2436_REV CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) --> H+ + phosphatidate (1-16:0, 2-18:1) + CTP 0.0 -r_2437 CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 6.687417754955684e-05 +r_2437 CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 6.687421023417254e-05 r_2437_REV CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) --> H+ + phosphatidate (1-16:1, 2-18:1) + CTP 0.0 r_2438 CDP-diacylglycerol synthase (1-18:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:0, 2-18:1) 0.0 r_2438_REV CDP-diacylglycerol synthase (1-18:0, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:0, 2-18:1) --> H+ + phosphatidate (1-18:0, 2-18:1) + CTP 0.0 @@ -2976,7 +2976,7 @@ r_2439 CDP-diacylglycerol synthase (1-18:1, 2-18:1), ER membrane 1.6138203786746 r_2439_REV CDP-diacylglycerol synthase (1-18:1, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:1, 2-18:1) --> H+ + phosphatidate (1-18:1, 2-18:1) + CTP 0.0 r_2440 CDP-diacylglycerol synthase (1-16:0, 2-16:1), mitochondrial membrane 1.6138203786746388 prot_P38221 + phosphatidate (1-16:0, 2-16:1) + CTP + H+ --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) 0.0 r_2440_REV CDP-diacylglycerol synthase (1-16:0, 2-16:1), mitochondrial membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) + CTP + H+ 0.0 -r_2441 CDP-diacylglycerol synthase (1-16:1, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0008362844722709401 +r_2441 CDP-diacylglycerol synthase (1-16:1, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0008362844722709413 r_2441_REV CDP-diacylglycerol synthase (1-16:1, 2-16:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) --> CTP + H+ + phosphatidate (1-16:1, 2-16:1) 0.0 r_2442 CDP-diacylglycerol synthase (1-18:0, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-18:0, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) 0.0 r_2442_REV CDP-diacylglycerol synthase (1-18:0, 2-16:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) --> CTP + H+ + phosphatidate (1-18:0, 2-16:1) 0.0 @@ -2984,12 +2984,12 @@ r_2443 CDP-diacylglycerol synthase (1-18:1, 2-16:1), mitochondrial membrane 1.37 r_2443_REV CDP-diacylglycerol synthase (1-18:1, 2-16:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) --> CTP + H+ + phosphatidate (1-18:1, 2-16:1) 0.0 r_2444 CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:0, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0 r_2444_REV CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) --> CTP + H+ + phosphatidate (1-16:0, 2-18:1) 0.0 -r_2445 CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 0.00019298383531152772 +r_2445 CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 0.00019298383531152655 r_2445_REV CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) --> CTP + H+ + phosphatidate (1-16:1, 2-18:1) 0.0 -r_2446 PS synthase (1-16:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-16:1) 5.846746774310264e-11 -r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0018202639565357203 +r_2446 PS synthase (1-16:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 +r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0018202640151935097 r_2448 PS synthase (1-18:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0034727008628694335 +r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0034727008625737923 r_2450 PS synthase (1-16:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 r_2451 PS synthase (1-16:1, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-18:1) 0.0 r_2452 PS synthase (1-18:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-18:1) 0.0 @@ -2998,8 +2998,8 @@ r_2454 PI synthase (1-16:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 r_2455 PI synthase (1-16:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) 0.0 r_2456 PI synthase (1-18:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:0, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 0.0 r_2457 PI synthase (1-18:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 -r_2458 PI synthase (1-16:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0007588092365482631 -r_2459 PI synthase (1-16:1, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 6.687417754955684e-05 +r_2458 PI synthase (1-16:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0007588092039423592 +r_2459 PI synthase (1-16:1, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 6.687421023417254e-05 r_2460 PI synthase (1-18:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) 0.0 r_2461 PI synthase (1-18:1, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:1, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) 0.0 r_2462 lysoPI acyltransferase (1-18:0, 2-16:1), ER membrane 128.62503770539482 prot_P38226 + stearoyl-CoA + sn-2-acyl-1-lysophosphatidylinositol (16:1) --> coenzyme A + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 0.0 @@ -3009,7 +3009,7 @@ r_2463_REV lysoPI acyltransferase (1-18:0, 2-18:1), ER membrane (reversible) 77. r_2464 PS decarboxylase (1-16:0, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-16:1) 0.0 r_2465 PS decarboxylase (1-16:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-16:1) 0.0010072557503258324 r_2466 PS decarboxylase (1-18:0, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_2467 PS decarboxylase (1-18:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.0034727008628694335 +r_2467 PS decarboxylase (1-18:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.0034727008625737923 r_2468 PS decarboxylase (1-16:0, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_2469 PS decarboxylase (1-16:1, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:1, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2470 PS decarboxylase (1-18:0, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3033,7 +3033,7 @@ r_2487 PS decarboxylase (1-18:1, 2-18:1), vacuolar membrane 0.09853409090909093 r_2488 PE methyltransferase (1-16:0, 2-16:1), ER membrane 1627.5240996397504 prot_P05374 + phosphatidylethanolamine (1-16:0, 2-16:1) + S-adenosyl-L-methionine --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) 0.0 r_2489 PE methyltransferase (1-16:1, 2-16:1), ER membrane 1772.794398518638 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) 0.0 r_2490 PE methyltransferase (1-18:0, 2-16:1), ER membrane 2311.996703472735 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) 0.0 -r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 169.40036397185034 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) 0.0034727008628694335 +r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 169.40036397185034 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) 0.0034727008625737945 r_2492 PE methyltransferase (1-16:0, 2-18:1), ER membrane 1187.9768182494734 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) 0.0 r_2493 PE methyltransferase (1-16:1, 2-18:1), ER membrane 1927.895637345238 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) 0.0 r_2494 PE methyltransferase (1-18:0, 2-18:1), ER membrane 1845.2830881909267 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3041,7 +3041,7 @@ r_2495 PE methyltransferase (1-18:1, 2-18:1), ER membrane 1146.7320397250028 pro r_2496 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) 0.0 r_2497 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) 0.0 r_2498 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) 0.0 -r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) 0.0034727008628694335 +r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) 0.0034727008625737923 r_2500 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) 0.0 r_2501 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) 0.0 r_2502 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3049,7 +3049,7 @@ r_2503 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-18:1), ER r_2504 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2505 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2506 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:0, 2-16:1) 0.0 -r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-16:1) 0.0034727008628694335 +r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-16:1) 0.0034727008625737923 r_2508 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_2509 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2510 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:0, 2-18:1) 0.0 @@ -3070,7 +3070,7 @@ r_2524 ethanolaminephosphotransferase (1-16:0, 2-18:1), ER membrane 12.259319894 r_2525 ethanolaminephosphotransferase (1-16:1, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2526 ethanolaminephosphotransferase (1-18:0, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 r_2527 ethanolaminephosphotransferase (1-18:1, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-18:1, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 -r_2528_EXP_1 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.002394439425894307 +r_2528_EXP_1 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.002394439523657025 r_2528_EXP_2 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2529_EXP_1 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2529_EXP_2 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-16:1) 0.0 @@ -3080,24 +3080,24 @@ r_2531_EXP_1 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 12.68654168 r_2531_EXP_2 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2532_EXP_1 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_2532_EXP_2 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0 -r_2533_EXP_1 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0009495522057621973 +r_2533_EXP_1 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0009495522056834543 r_2533_EXP_2 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0 -r_2534_EXP_1 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.00027766980278451256 +r_2534_EXP_1 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0002776698027845441 r_2534_EXP_2 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2535_EXP_1 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_2535_EXP_2 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_2536 phosphatidylglycerolphosphate synthase (1-16:0, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:0, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-16:1) 0.0 -r_2537 phosphatidylglycerolphosphate synthase (1-16:1, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) 0.0008362844722709401 +r_2537 phosphatidylglycerolphosphate synthase (1-16:1, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) 0.0008362844722709413 r_2538 phosphatidylglycerolphosphate synthase (1-18:0, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-18:0, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:0, 2-16:1) 0.0 r_2539 phosphatidylglycerolphosphate synthase (1-18:1, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-18:1, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:1, 2-16:1) 0.0 r_2540 phosphatidylglycerolphosphate synthase (1-16:0, 2-18:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:0, 2-18:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-18:1) 0.0 -r_2541 phosphatidylglycerolphosphate synthase (1-16:1, 2-18:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-18:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) 0.00019298383531152772 +r_2541 phosphatidylglycerolphosphate synthase (1-16:1, 2-18:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-18:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) 0.00019298383531152655 r_2542 PGP phosphatase (1-16:0, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-16:1) + H2O --> 2.0 H+ + phosphatidylglycerol (1-16:0, 2-16:1) + phosphate 0.0 -r_2543 PGP phosphatase (1-16:1, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-16:1) 0.0008362844722709402 +r_2543 PGP phosphatase (1-16:1, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-16:1) 0.0008362844722709413 r_2544 PGP phosphatase (1-18:0, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:0, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-18:0, 2-16:1) 0.0 r_2545 PGP phosphatase (1-18:1, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:1, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-18:1, 2-16:1) 0.0 r_2546 PGP phosphatase (1-16:0, 2-18:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-18:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:0, 2-18:1) 0.0 -r_2547 PGP phosphatase (1-16:1, 2-18:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-18:1) 0.00019298383531152772 +r_2547 PGP phosphatase (1-16:1, 2-18:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-18:1) 0.00019298383531152655 r_2548 CL synthase (1-16:0, 2-16:1, 3-16:0, 4-16:1), mitochondrial membrane 4334.5245830625945 prot_Q07560 + CDP-diacylglycerol (1-16:0, 2-16:1) + phosphatidylglycerol (1-16:0, 2-16:1) --> 2.0 H+ + CMP + cardiolipin (1-16:0, 2-16:1, 3-16:0, 4-16:1) 0.0 r_2549 CL synthase (1-16:0, 2-16:1, 3-16:1, 4-16:1), mitochondrial membrane 4334.5245830625945 prot_Q07560 + CDP-diacylglycerol (1-16:0, 2-16:1) + phosphatidylglycerol (1-16:1, 2-16:1) --> 2.0 H+ + CMP + cardiolipin (1-16:0, 2-16:1, 3-16:1, 4-16:1) 0.0 r_2550 CL synthase (1-16:0, 2-16:1, 3-18:0, 4-16:1), mitochondrial membrane 4334.5245830625945 prot_Q07560 + CDP-diacylglycerol (1-16:0, 2-16:1) + phosphatidylglycerol (1-18:0, 2-16:1) --> 2.0 H+ + CMP + cardiolipin (1-16:0, 2-16:1, 3-18:0, 4-16:1) 0.0 @@ -3170,10 +3170,10 @@ r_2616 CL (1-16:0, 2-18:1, 3-16:0, 4-18:1) phospholipase (3-position), mitochond r_2617 CL (1-16:1, 2-18:1, 3-16:0, 4-16:1) phospholipase (3-position), mitochondrial membrane 8.108213373216179 prot_P53264 + H2O + cardiolipin (1-16:1, 2-18:1, 3-16:0, 4-16:1) --> H+ + palmitate + monolysocardiolipin (1-16:1, 2-18:1, 4-16:1) 0.0 r_2618 CL (1-16:1, 2-18:1, 3-18:0, 4-16:1) phospholipase (3-position), mitochondrial membrane 8.108213373216179 prot_P53264 + H2O + cardiolipin (1-16:1, 2-18:1, 3-18:0, 4-16:1) --> H+ + stearate + monolysocardiolipin (1-16:1, 2-18:1, 4-16:1) 0.0 r_2619 CL (1-16:1, 2-18:1, 3-16:0, 4-18:1) phospholipase (3-position), mitochondrial membrane 8.108213373216179 prot_P53264 + H2O + cardiolipin (1-16:1, 2-18:1, 3-16:0, 4-18:1) --> H+ + palmitate + monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) 0.0 -r_2620 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.00014896057157158318 +r_2620 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 r_2620_REV MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2621 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.0 -r_2621_REV MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) 0.00014896057157158318 +r_2621_REV MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2622 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-18:0, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (18:0) 0.0 r_2622_REV MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (18:0) --> monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_2623 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 @@ -3227,8 +3227,8 @@ r_2646_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mi r_2647 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2647_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2648 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 -r_2648_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 0.00014896057157158318 -r_2649 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.00014896057157158318 +r_2648_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 0.0 +r_2649 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.0 r_2649_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2650 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) 0.0 r_2650_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) 0.0 @@ -3323,8 +3323,8 @@ r_2694_REV MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mi r_2695 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) --> cardiolipin (1-16:1, 2-18:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2695_REV MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-18:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) --> monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2696 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) --> 1-acylglycerophosphocholine (16:0) + cardiolipin (1-18:1, 2-18:1, 3-18:1, 4-16:1) 0.0 -r_2696_REV MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + 1-acylglycerophosphocholine (16:0) + cardiolipin (1-18:1, 2-18:1, 3-18:1, 4-16:1) --> monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 0.0 -r_2697 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) --> 1-acylglycerophosphocholine (16:1) + cardiolipin (1-18:1, 2-18:1, 3-18:1, 4-16:1) 0.0 +r_2696_REV MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + 1-acylglycerophosphocholine (16:0) + cardiolipin (1-18:1, 2-18:1, 3-18:1, 4-16:1) --> monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 0.0001489606695512331 +r_2697 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) --> 1-acylglycerophosphocholine (16:1) + cardiolipin (1-18:1, 2-18:1, 3-18:1, 4-16:1) 0.0001489606695512331 r_2697_REV MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + 1-acylglycerophosphocholine (16:1) + cardiolipin (1-18:1, 2-18:1, 3-18:1, 4-16:1) --> monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2698 MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) --> 1-acylglycerophosphocholine (18:0) + cardiolipin (1-18:1, 2-18:1, 3-18:1, 4-16:1) 0.0 r_2698_REV MLCL (2-18:1, 3-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + 1-acylglycerophosphocholine (18:0) + cardiolipin (1-18:1, 2-18:1, 3-18:1, 4-16:1) --> monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) 0.0 @@ -3538,10 +3538,10 @@ r_2802 MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitoch r_2802_REV MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-18:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) --> monolysocardiolipin (1-16:1, 2-18:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2803 MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-18:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-18:1) --> cardiolipin (1-16:1, 2-18:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2803_REV MLCL (1-16:1, 2-18:1, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-18:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) --> monolysocardiolipin (1-16:1, 2-18:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-18:1) 0.0 -r_2804 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) + 1-acylglycerophosphocholine (16:0) 0.0 +r_2804 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) + 1-acylglycerophosphocholine (16:0) 0.0001489606695512331 r_2804_REV MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2805 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) + phosphatidylcholine (1-16:1, 2-16:1) --> cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) + 1-acylglycerophosphocholine (16:1) 0.0 -r_2805_REV MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) + phosphatidylcholine (1-16:1, 2-16:1) 0.0 +r_2805_REV MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) + phosphatidylcholine (1-16:1, 2-16:1) 0.0001489606695512331 r_2806 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) + phosphatidylcholine (1-18:0, 2-16:1) --> cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) + 1-acylglycerophosphocholine (18:0) 0.0 r_2806_REV MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) + 1-acylglycerophosphocholine (18:0) --> monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) + phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_2807 MLCL (1-16:1, 2-18:1, 4-18:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) + phosphatidylcholine (1-18:1, 2-16:1) --> cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) + 1-acylglycerophosphocholine (18:1) 0.0 @@ -4007,15 +4007,15 @@ r_3095 PI 4,5-P2 phospholipase C (1-16:1, 2-18:1), nucleus 0.0321987491713981 pr r_3096 PI 4,5-P2 phospholipase C (1-18:0, 2-18:1), nucleus 0.0321987491713981 prot_P32383 + H2O + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) --> 1D-myo-inositol 1,4,5-trisphosphate + 6.0 H+ + diglyceride (1-18:0, 2-18:1) 0.0 r_3097 PI 4,5-P2 phospholipase C (1-18:1, 2-18:1), nucleus 0.0321987491713981 prot_P32383 + H2O + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) --> 1D-myo-inositol 1,4,5-trisphosphate + 6.0 H+ + diglyceride (1-18:1, 2-18:1) 0.0 r_3098 PG phospholipase C (1-16:0, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:0, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:0, 2-16:1) 0.0 -r_3099 PG phospholipase C (1-16:1, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-16:1) 0.0008362844722709401 +r_3099 PG phospholipase C (1-16:1, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-16:1) 0.0008362844722709413 r_3100 PG phospholipase C (1-18:0, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-18:0, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-18:0, 2-16:1) 0.0 r_3101 PG phospholipase C (1-18:1, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-18:1, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-18:1, 2-16:1) 0.0 r_3102 PG phospholipase C (1-16:0, 2-18:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:0, 2-18:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:0, 2-18:1) 0.0 -r_3103 PG phospholipase C (1-16:1, 2-18:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-18:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-18:1) 0.00019298383531152772 +r_3103 PG phospholipase C (1-16:1, 2-18:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-18:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-18:1) 0.00019298383531152655 r_3104 PC phospholipase D (1-16:0, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + phosphatidylcholine (1-16:0, 2-16:1) + H2O --> choline + phosphatidate (1-16:0, 2-16:1) 0.0 -r_3105 PC phospholipase D (1-16:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-16:1) --> choline + phosphatidate (1-16:1, 2-16:1) 0.00014896057157158318 +r_3105 PC phospholipase D (1-16:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-16:1) --> choline + phosphatidate (1-16:1, 2-16:1) 0.0001489606695512331 r_3106 PC phospholipase D (1-18:0, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:0, 2-16:1) --> choline + phosphatidate (1-18:0, 2-16:1) 0.0 -r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:1, 2-16:1) --> choline + phosphatidate (1-18:1, 2-16:1) 0.0034727008628694335 +r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:1, 2-16:1) --> choline + phosphatidate (1-18:1, 2-16:1) 0.0034727008625737923 r_3108 PC phospholipase D (1-16:0, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:0, 2-18:1) --> choline + phosphatidate (1-16:0, 2-18:1) 0.0 r_3109 PC phospholipase D (1-16:1, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-18:1) --> choline + phosphatidate (1-16:1, 2-18:1) 0.0 r_3110 PC phospholipase D (1-18:0, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:0, 2-18:1) --> choline + phosphatidate (1-18:0, 2-18:1) 0.0 @@ -4283,7 +4283,7 @@ r_3268_EXP_1 TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle 0.9775745257452 r_3268_EXP_2 TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle 2.3197154471544716 prot_P36165 + triglyceride (1-16:1, 2-16:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:1, 2-16:1) 0.0 r_3268_EXP_3 TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle 1.6624435411020777 prot_P40308 + triglyceride (1-16:1, 2-16:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:1, 2-16:1) 0.0 r_3268_EXP_4 TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle 1.9131887985546523 prot_Q12043 + triglyceride (1-16:1, 2-16:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:1, 2-16:1) 0.0 -r_3269_EXP_1 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 0.9775745257452575 prot_P38139 + triglyceride (1-16:1, 2-16:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:1, 2-16:1) 0.0005472067037335731 +r_3269_EXP_1 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 0.9775745257452575 prot_P38139 + triglyceride (1-16:1, 2-16:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:1, 2-16:1) 0.0 r_3269_EXP_2 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 2.3197154471544716 prot_P36165 + triglyceride (1-16:1, 2-16:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:1, 2-16:1) 0.0 r_3269_EXP_3 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 1.6624435411020777 prot_P40308 + triglyceride (1-16:1, 2-16:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:1, 2-16:1) 0.0 r_3269_EXP_4 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 1.9131887985546523 prot_Q12043 + triglyceride (1-16:1, 2-16:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:1, 2-16:1) 0.0 @@ -4331,7 +4331,7 @@ r_3280_EXP_1 TAG lipase (1-16:0, 2-18:1, 3-16:0), lipid particle 0.9775745257452 r_3280_EXP_2 TAG lipase (1-16:0, 2-18:1, 3-16:0), lipid particle 2.3197154471544716 prot_P36165 + triglyceride (1-16:0, 2-18:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:0, 2-18:1) 0.0 r_3280_EXP_3 TAG lipase (1-16:0, 2-18:1, 3-16:0), lipid particle 1.6624435411020777 prot_P40308 + triglyceride (1-16:0, 2-18:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:0, 2-18:1) 0.0 r_3280_EXP_4 TAG lipase (1-16:0, 2-18:1, 3-16:0), lipid particle 1.9131887985546523 prot_Q12043 + triglyceride (1-16:0, 2-18:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:0, 2-18:1) 0.0 -r_3281_EXP_1 TAG lipase (1-16:0, 2-18:1, 3-16:1), lipid particle 0.9775745257452575 prot_P38139 + triglyceride (1-16:0, 2-18:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:0, 2-18:1) 0.0 +r_3281_EXP_1 TAG lipase (1-16:0, 2-18:1, 3-16:1), lipid particle 0.9775745257452575 prot_P38139 + triglyceride (1-16:0, 2-18:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:0, 2-18:1) 0.0005472083134696547 r_3281_EXP_2 TAG lipase (1-16:0, 2-18:1, 3-16:1), lipid particle 2.3197154471544716 prot_P36165 + triglyceride (1-16:0, 2-18:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:0, 2-18:1) 0.0 r_3281_EXP_3 TAG lipase (1-16:0, 2-18:1, 3-16:1), lipid particle 1.6624435411020777 prot_P40308 + triglyceride (1-16:0, 2-18:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:0, 2-18:1) 0.0 r_3281_EXP_4 TAG lipase (1-16:0, 2-18:1, 3-16:1), lipid particle 1.9131887985546523 prot_Q12043 + triglyceride (1-16:0, 2-18:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:0, 2-18:1) 0.0 @@ -4622,30 +4622,30 @@ r_3506 IPC synthase (PI (1-18:0, 2-18:1) ceramide-4 (C26)) 142.7071089252805 pro r_3507 IPC synthase (PI (1-18:1, 2-18:1) ceramide-4 (C26)) 142.7071089252805 prot_P36107 + 80.47148814754162 prot_Q06346 + ceramide-4 (C26) + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> inositol-P-ceramide D (C26) + diglyceride (1-18:1, 2-18:1) 0.0 r_3508 laurate transport, cytoplasm-ER membrane laurate --> laurate 0.00044172356996047285 r_3508_REV laurate transport, cytoplasm-ER membrane (reversible) laurate --> laurate 0.0 -r_3509 myristate transport, cytoplasm-ER membrane myristate --> myristate 0.00025539365650321597 +r_3509 myristate transport, cytoplasm-ER membrane myristate --> myristate 0.00025539366341234895 r_3509_REV myristate transport, cytoplasm-ER membrane (reversible) myristate --> myristate 0.0 r_3510 palmitate transport, cytoplasm-ER membrane palmitate --> palmitate 0.0 r_3510_REV palmitate transport, cytoplasm-ER membrane (reversible) palmitate --> palmitate 0.0 r_3511 palmitoleate transport, cytoplasm-ER membrane palmitoleate --> palmitoleate 0.0 -r_3511_REV palmitoleate transport, cytoplasm-ER membrane (reversible) palmitoleate --> palmitoleate 4.85703771638254e-10 +r_3511_REV palmitoleate transport, cytoplasm-ER membrane (reversible) palmitoleate --> palmitoleate -1.117289749032978e-09 r_3512 stearate transport, cytoplasm-ER membrane stearate --> stearate 0.0 r_3512_REV stearate transport, cytoplasm-ER membrane (reversible) stearate --> stearate 0.0 r_3513 oleate transport, cytoplasm-ER membrane oleate --> oleate 0.0 r_3513_REV oleate transport, cytoplasm-ER membrane (reversible) oleate --> oleate 0.0 -r_3514 malonyl-CoA transport, cytoplasm-ER membrane malonyl-CoA --> malonyl-CoA 0.0026256832941352337 +r_3514 malonyl-CoA transport, cytoplasm-ER membrane malonyl-CoA --> malonyl-CoA 0.002625683300610998 r_3514_REV malonyl-CoA transport, cytoplasm-ER membrane (reversible) malonyl-CoA --> malonyl-CoA 0.0 -r_3515 lauroyl-CoA transport, cytoplasm-ER membrane lauroyl-CoA --> lauroyl-CoA 0.0 +r_3515 lauroyl-CoA transport, cytoplasm-ER membrane lauroyl-CoA --> lauroyl-CoA 0.00044172356996047285 r_3515_REV lauroyl-CoA transport, cytoplasm-ER membrane (reversible) lauroyl-CoA --> lauroyl-CoA 0.0 -r_3516 myristoyl-CoA transport, cytoplasm-ER membrane myristoyl-CoA --> myristoyl-CoA 0.0002553936565032158 +r_3516 myristoyl-CoA transport, cytoplasm-ER membrane myristoyl-CoA --> myristoyl-CoA 0.00025539366341234895 r_3516_REV myristoyl-CoA transport, cytoplasm-ER membrane (reversible) myristoyl-CoA --> myristoyl-CoA 0.0 -r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane palmitoyl-CoA --> palmitoyl-CoA 0.012065014317168105 +r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane palmitoyl-CoA --> palmitoyl-CoA 0.011980027931401956 r_3517_REV palmitoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3518 palmitoleoyl-CoA transport, cytoplasm-ER membrane palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 -r_3518_REV palmitoleoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.00028144707955366557 -r_3519 stearoyl-CoA transport, cytoplasm-ER membrane stearoyl-CoA --> stearoyl-CoA 0.0039730442002201775 +r_3518_REV palmitoleoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.00019646069400727024 +r_3519 stearoyl-CoA transport, cytoplasm-ER membrane stearoyl-CoA --> stearoyl-CoA 0.003454069266979322 r_3519_REV stearoyl-CoA transport, cytoplasm-ER membrane (reversible) stearoyl-CoA --> stearoyl-CoA 0.0 r_3520 oleoyl-CoA transport, cytoplasm-ER membrane oleoyl-CoA --> oleoyl-CoA 0.0 -r_3520_REV oleoyl-CoA transport, cytoplasm-ER membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.00027766980278451256 +r_3520_REV oleoyl-CoA transport, cytoplasm-ER membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.0002776698027845441 r_3521 icosanoyl-CoA transport, cytoplasm-ER membrane icosanoyl-CoA --> icosanoyl-CoA 0.0 r_3521_REV icosanoyl-CoA transport, cytoplasm-ER membrane (reversible) icosanoyl-CoA --> icosanoyl-CoA 0.0 r_3522 docosanoyl-CoA transport, cytoplasm-ER membrane docosanoyl-CoA --> docosanoyl-CoA 0.0 @@ -4653,57 +4653,57 @@ r_3522_REV docosanoyl-CoA transport, cytoplasm-ER membrane (reversible) docosano r_3523 tetracosanoyl-CoA transport, cytoplasm-ER membrane tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 r_3523_REV tetracosanoyl-CoA transport, cytoplasm-ER membrane (reversible) tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 r_3524 hexacosanoyl-CoA transport, cytoplasm-ER membrane hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 -r_3524_REV hexacosanoyl-CoA transport, cytoplasm-ER membrane (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0003717106244277723 -r_3525 H+ transport, cytoplasm-ER membrane H+ --> H+ 0.0031458825293727982 +r_3524_REV hexacosanoyl-CoA transport, cytoplasm-ER membrane (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0003717106243194283 +r_3525 H+ transport, cytoplasm-ER membrane H+ --> H+ 0.0030608960663486015 r_3525_REV H+ transport, cytoplasm-ER membrane (reversible) H+ --> H+ 0.0 r_3526_EXP_1 H2O transport, cytoplasm-ER membrane 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_3526_EXP_2 H2O transport, cytoplasm-ER membrane 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_3526_REV_EXP_1 H2O transport, cytoplasm-ER membrane (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.028008166224898545 +r_3526_REV_EXP_1 H2O transport, cytoplasm-ER membrane (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.02783819346028159 r_3526_REV_EXP_2 H2O transport, cytoplasm-ER membrane (reversible) 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_3527 CO2 transport, cytoplasm-ER membrane carbon dioxide --> carbon dioxide 0.0 -r_3527_REV CO2 transport, cytoplasm-ER membrane (reversible) carbon dioxide --> carbon dioxide 0.002625683294135251 +r_3527_REV CO2 transport, cytoplasm-ER membrane (reversible) carbon dioxide --> carbon dioxide 0.0026256833006110076 r_3528 coenzyme A transport, cytoplasm-ER membrane coenzyme A --> coenzyme A 0.0 -r_3528_REV coenzyme A transport, cytoplasm-ER membrane (reversible) coenzyme A --> coenzyme A 0.01798830796126085 -r_3529 NADPH transport, cytoplasm-ER membrane NADPH --> NADPH 0.005251366588270498 +r_3528_REV coenzyme A transport, cytoplasm-ER membrane (reversible) coenzyme A --> coenzyme A 0.017911056611253813 +r_3529 NADPH transport, cytoplasm-ER membrane NADPH --> NADPH 0.005251366601222016 r_3529_REV NADPH transport, cytoplasm-ER membrane (reversible) NADPH --> NADPH 0.0 r_3530 NADP(+) transport, cytoplasm-ER membrane NADP(+) --> NADP(+) 0.0 -r_3530_REV NADP(+) transport, cytoplasm-ER membrane (reversible) NADP(+) --> NADP(+) 0.005251366588270498 -r_3531 O2 transport, cytoplasm-ER membrane oxygen --> oxygen 0.012691241465381652 +r_3530_REV NADP(+) transport, cytoplasm-ER membrane (reversible) NADP(+) --> NADP(+) 0.005251366601222016 +r_3531 O2 transport, cytoplasm-ER membrane oxygen --> oxygen 0.012606255079835295 r_3531_REV O2 transport, cytoplasm-ER membrane (reversible) oxygen --> oxygen 0.0 -r_3532 NADH transport, cytoplasm-ER membrane NADH --> NADH 0.023865103497314008 +r_3532 NADH transport, cytoplasm-ER membrane NADH --> NADH 0.023780117111767654 r_3532_REV NADH transport, cytoplasm-ER membrane (reversible) NADH --> NADH 0.0 r_3533 NAD transport, cytoplasm-ER membrane NAD --> NAD 0.0 -r_3533_REV NAD transport, cytoplasm-ER membrane (reversible) NAD --> NAD 0.023865103497314008 -r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.006677262961456862 +r_3533_REV NAD transport, cytoplasm-ER membrane (reversible) NAD --> NAD 0.023780117111767654 +r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.00667726296143023 r_3534_REV glycerol 3-phosphate transport, cytoplasm-ER membrane (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3535 dihydroxyacetone phosphate transport, cytoplasm-ER membrane dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3535_REV dihydroxyacetone phosphate transport, cytoplasm-ER membrane (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3536 diphosphate transport, cytoplasm-ER membrane diphosphate --> diphosphate 0.0 -r_3536_REV diphosphate transport, cytoplasm-ER membrane (reversible) diphosphate --> diphosphate 0.006560371376227143 +r_3536_REV diphosphate transport, cytoplasm-ER membrane (reversible) diphosphate --> diphosphate 0.006118649409233583 r_3537 phosphate transport, cytoplasm-ER membrane phosphate --> phosphate 0.0 r_3537_REV phosphate transport, cytoplasm-ER membrane (reversible) phosphate --> phosphate 0.0 -r_3538 CTP transport, cytoplasm-ER membrane CTP --> CTP 0.006118648291970442 +r_3538 CTP transport, cytoplasm-ER membrane CTP --> CTP 0.006118648291943834 r_3538_REV CTP transport, cytoplasm-ER membrane (reversible) CTP --> CTP 0.0 r_3539 CDP transport, cytoplasm-ER membrane CDP --> CDP 0.0 r_3539_REV CDP transport, cytoplasm-ER membrane (reversible) CDP --> CDP 0.0 r_3540 CMP transport, cytoplasm-ER membrane CMP --> CMP 0.0 -r_3540_REV CMP transport, cytoplasm-ER membrane (reversible) CMP --> CMP 0.009740309726411458 +r_3540_REV CMP transport, cytoplasm-ER membrane (reversible) CMP --> CMP 0.009740309824068856 r_3541 CDP-ethanolamine transport, cytoplasm-ER membrane CDP-ethanolamine --> CDP-ethanolamine 0.0 r_3541_REV CDP-ethanolamine transport, cytoplasm-ER membrane (reversible) CDP-ethanolamine --> CDP-ethanolamine 0.0 -r_3542 CDP-choline transport, cytoplasm-ER membrane CDP-choline --> CDP-choline 0.0036216614344410166 +r_3542 CDP-choline transport, cytoplasm-ER membrane CDP-choline --> CDP-choline 0.0036216615321250233 r_3542_REV CDP-choline transport, cytoplasm-ER membrane (reversible) CDP-choline --> CDP-choline 0.0 -r_3543 ATP transport, cytoplasm-ER membrane ATP --> ATP 0.0004417230842567012 -r_3543_REV ATP transport, cytoplasm-ER membrane (reversible) ATP --> ATP 0.0 -r_3544 AMP transport, cytoplasm-ER membrane AMP --> AMP 0.0 -r_3544_REV AMP transport, cytoplasm-ER membrane (reversible) AMP --> AMP 0.0004417230842567012 -r_3545 L-serine transport, cytoplasm-ER membrane 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.005292964877872622 +r_3543 ATP transport, cytoplasm-ER membrane ATP --> ATP 0.0 +r_3543_REV ATP transport, cytoplasm-ER membrane (reversible) ATP --> ATP -1.117289749032978e-09 +r_3544 AMP transport, cytoplasm-ER membrane AMP --> AMP -1.117289749032978e-09 +r_3544_REV AMP transport, cytoplasm-ER membrane (reversible) AMP --> AMP 0.0 +r_3545 L-serine transport, cytoplasm-ER membrane 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.005292964877767302 r_3545_REV L-serine transport, cytoplasm-ER membrane (reversible) 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.0 -r_3546 myo-inositol transport, cytoplasm-ER membrane myo-inositol --> myo-inositol 0.00082568341409782 +r_3546 myo-inositol transport, cytoplasm-ER membrane myo-inositol --> myo-inositol 0.0008256834141765318 r_3546_REV myo-inositol transport, cytoplasm-ER membrane (reversible) myo-inositol --> myo-inositol 0.0 -r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.010418102588552984 +r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.010418102587748052 r_3547_REV S-adenosyl-L-methionine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.0 r_3548 S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.0 -r_3548_REV S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.010418102588553543 +r_3548_REV S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.010418102587748038 r_3549 episterol transport, cytoplasm-ER membrane episterol --> episterol 0.0 r_3549_REV episterol transport, cytoplasm-ER membrane (reversible) episterol --> episterol 0.0 r_3550 fecosterol transport, cytoplasm-ER membrane fecosterol --> fecosterol 0.0 @@ -4716,15 +4716,15 @@ r_3553 zymosterol transport, cytoplasm-ER membrane zymosterol --> zymosterol 3.6 r_3553_REV zymosterol transport, cytoplasm-ER membrane (reversible) zymosterol --> zymosterol 0.0 r_3554 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3554_REV diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3555 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0013834911760045132 +r_3555 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.00031730953913846043 r_3555_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3556 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3556_REV diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3557 diglyceride (1-18:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3557_REV diglyceride (1-18:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 -r_3558 diglyceride (1-16:0, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 +r_3558 diglyceride (1-16:0, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0005472083134696547 r_3558_REV diglyceride (1-16:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 -r_3559 diglyceride (1-16:1, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.00019298383531152772 +r_3559 diglyceride (1-16:1, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.00019298383531152655 r_3559_REV diglyceride (1-16:1, 2-18:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3560 diglyceride (1-18:0, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 r_3560_REV diglyceride (1-18:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 @@ -4739,9 +4739,9 @@ r_3564_REV 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, cytoplasm- r_3565 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 r_3565_REV 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 r_3566 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0 -r_3566_REV 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0007588092365482631 +r_3566_REV 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0007588092039423592 r_3567 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 0.0 -r_3567_REV 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 6.687417754955684e-05 +r_3567_REV 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 6.687421023417254e-05 r_3568 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) 0.0 r_3568_REV 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) 0.0 r_3569 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) 0.0 @@ -4751,24 +4751,24 @@ r_3570_REV sn-glycero-3-phosphocholine transport, ER membrane-cytoplasm (reversi r_3571 hexadecanoate (n-C16:0) transport, cytoplasm-lipid particle palmitate --> palmitate 0.0 r_3571_REV hexadecanoate (n-C16:0) transport, cytoplasm-lipid particle (reversible) palmitate --> palmitate 0.0 r_3572 hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle palmitoleate --> palmitoleate 0.0 -r_3572_REV hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle (reversible) palmitoleate --> palmitoleate 0.0005472067037335731 +r_3572_REV hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle (reversible) palmitoleate --> palmitoleate 0.0005472083134696547 r_3573 octadecanoate (n-C18:0) transport, cytoplasm-lipid particle stearate --> stearate 0.0 r_3573_REV octadecanoate (n-C18:0) transport, cytoplasm-lipid particle (reversible) stearate --> stearate 0.0 r_3574 octadecenoate (n-C18:1) transport, cytoplasm-lipid particle oleate --> oleate 0.0 r_3574_REV octadecenoate (n-C18:1) transport, cytoplasm-lipid particle (reversible) oleate --> oleate 0.0 r_3575 lauroyl-CoA transport, cytoplasm-lipid particle lauroyl-CoA --> lauroyl-CoA 0.0 -r_3575_REV lauroyl-CoA transport, cytoplasm-lipid particle (reversible) lauroyl-CoA --> lauroyl-CoA 0.0 +r_3575_REV lauroyl-CoA transport, cytoplasm-lipid particle (reversible) lauroyl-CoA --> lauroyl-CoA 0.00044172356996047285 r_3576 myristoyl-CoA transport, cytoplasm-lipid particle myristoyl-CoA --> myristoyl-CoA 0.0 -r_3576_REV myristoyl-CoA transport, cytoplasm-lipid particle (reversible) myristoyl-CoA --> myristoyl-CoA 0.0002553936565032158 +r_3576_REV myristoyl-CoA transport, cytoplasm-lipid particle (reversible) myristoyl-CoA --> myristoyl-CoA 0.00025539366341234895 r_3577 palmitoyl-CoA transport, cytoplasm-lipid particle palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3577_REV palmitoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3578 palmitoleoyl-CoA transport, cytoplasm-lipid particle palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3578_REV palmitoleoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 -r_3579 stearoyl-CoA transport, cytoplasm-lipid particle stearoyl-CoA --> stearoyl-CoA 0.00027766980278451256 +r_3579 stearoyl-CoA transport, cytoplasm-lipid particle stearoyl-CoA --> stearoyl-CoA 0.000796644735917025 r_3579_REV stearoyl-CoA transport, cytoplasm-lipid particle (reversible) stearoyl-CoA --> stearoyl-CoA 0.0 -r_3580 oleoyl-CoA transport, cytoplasm-lipid particle oleoyl-CoA --> oleoyl-CoA 0.00027766980278451256 +r_3580 oleoyl-CoA transport, cytoplasm-lipid particle oleoyl-CoA --> oleoyl-CoA 0.0002776698027845441 r_3580_REV oleoyl-CoA transport, cytoplasm-lipid particle (reversible) oleoyl-CoA --> oleoyl-CoA 0.0 -r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle glycerol 3-phosphate --> glycerol 3-phosphate 0.00027766980278451256 +r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle glycerol 3-phosphate --> glycerol 3-phosphate 0.0002776698027845441 r_3581_REV glycerol 3-phosphate transport, cytoplasm-lipid particle (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3582 dihydroxyacetone phosphate transport, cytoplasm-lipid particle dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3582_REV dihydroxyacetone phosphate transport, cytoplasm-lipid particle (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 @@ -4776,29 +4776,29 @@ r_3583 NADPH transport, cytoplasm-lipid particle NADPH --> NADPH 0.0 r_3583_REV NADPH transport, cytoplasm-lipid particle (reversible) NADPH --> NADPH 0.0 r_3584 NADP(+) transport, cytoplasm-lipid particle NADP(+) --> NADP(+) 0.0 r_3584_REV NADP(+) transport, cytoplasm-lipid particle (reversible) NADP(+) --> NADP(+) 0.0 -r_3585 ATP transport, cytoplasm-lipid particle ATP --> ATP 0.00025539365650321597 +r_3585 ATP transport, cytoplasm-lipid particle ATP --> ATP 0.0006971172333728219 r_3585_REV ATP transport, cytoplasm-lipid particle (reversible) ATP --> ATP 0.0 -r_3586 AMP transport, cytoplasm-lipid particle AMP --> AMP 0.0 -r_3586_REV AMP transport, cytoplasm-lipid particle (reversible) AMP --> AMP 0.00025539365650321597 +r_3586 AMP transport, cytoplasm-lipid particle AMP --> AMP 999.9993028827666 +r_3586_REV AMP transport, cytoplasm-lipid particle (reversible) AMP --> AMP 1000.0 r_3587 diphosphate transport, cytoplasm-lipid particle diphosphate --> diphosphate 0.0 -r_3587_REV diphosphate transport, cytoplasm-lipid particle (reversible) diphosphate --> diphosphate 0.00025539365650321597 +r_3587_REV diphosphate transport, cytoplasm-lipid particle (reversible) diphosphate --> diphosphate 0.0006971172333728219 r_3588 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3588_REV diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3589 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 -r_3589_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0005472067037335731 +r_3589 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0005189749331324809 +r_3589_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3590 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3590_REV diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3591 diglyceride (1-18:1, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3591_REV diglyceride (1-18:1, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3592 diglyceride (1-16:0, 2-18:1) transport, cytoplasm-lipid particle diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 -r_3592_REV diglyceride (1-16:0, 2-18:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 +r_3592_REV diglyceride (1-16:0, 2-18:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0005472083134696547 r_3593 diglyceride (1-16:1, 2-18:1) transport, cytoplasm-lipid particle diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3593_REV diglyceride (1-16:1, 2-18:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3594 diglyceride (1-18:0, 2-18:1) transport, cytoplasm-lipid particle diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 r_3594_REV diglyceride (1-18:0, 2-18:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 r_3595 diglyceride (1-18:1, 2-18:1) transport, cytoplasm-lipid particle diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 r_3595_REV diglyceride (1-18:1, 2-18:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 -r_3596 H2O transport, cytoplasm-lipid particle H2O --> H2O 0.0005472067037335731 +r_3596 H2O transport, cytoplasm-lipid particle H2O --> H2O 0.0005472083134696547 r_3596_REV H2O transport, cytoplasm-lipid particle (reversible) H2O --> H2O 0.0 r_3597 glycerol transport, lipid particle-cytoplasm glycerol --> glycerol 0.0 r_3597_REV glycerol transport, lipid particle-cytoplasm (reversible) glycerol --> glycerol 0.0 @@ -4812,10 +4812,10 @@ r_3601 ATP transport, cytoplasm-cell envelope ATP --> ATP 0.0 r_3601_REV ATP transport, cytoplasm-cell envelope (reversible) ATP --> ATP 0.0 r_3602 ADP transport, cytoplasm-cell envelope ADP --> ADP 0.0 r_3602_REV ADP transport, cytoplasm-cell envelope (reversible) ADP --> ADP 0.0 -r_3603 H+ transport, cytoplasm-cell envelope H+ --> H+ 0.0035847840019923947 +r_3603 H+ transport, cytoplasm-cell envelope H+ --> H+ 0.0035847840996764036 r_3603_REV H+ transport, cytoplasm-cell envelope (reversible) H+ --> H+ 0.0 r_3604_EXP_1 H2O transport, cytoplasm-cell envelope 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 -r_3604_EXP_2 H2O transport, cytoplasm-cell envelope 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0036585388668896384 +r_3604_EXP_2 H2O transport, cytoplasm-cell envelope 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0036585389645736473 r_3604_EXP_3 H2O transport, cytoplasm-cell envelope 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_3604_REV_EXP_1 H2O transport, cytoplasm-cell envelope (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_3604_REV_EXP_2 H2O transport, cytoplasm-cell envelope (reversible) 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0 @@ -4938,12 +4938,12 @@ r_3660 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transpor r_3660_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) 0.0 r_3661 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 r_3661_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 -r_3662 H2O transport, cytoplasm-Golgi membrane H2O --> H2O 0.0034286775991294893 +r_3662 H2O transport, cytoplasm-Golgi membrane H2O --> H2O 0.0034286776968134964 r_3662_REV H2O transport, cytoplasm-Golgi membrane (reversible) H2O --> H2O 0.0 r_3663 phosphate transport, cytoplasm-Golgi membrane phosphate --> phosphate 0.0 -r_3663_REV phosphate transport, cytoplasm-Golgi membrane (reversible) phosphate --> phosphate 0.0034286775991294893 +r_3663_REV phosphate transport, cytoplasm-Golgi membrane (reversible) phosphate --> phosphate 0.0034286776968134964 r_3664 H+ transport, cytoplasm-Golgi membrane H+ --> H+ 0.0 -r_3664_REV H+ transport, cytoplasm-Golgi membrane (reversible) H+ --> H+ 0.0068573551982589786 +r_3664_REV H+ transport, cytoplasm-Golgi membrane (reversible) H+ --> H+ 0.006857355393626993 r_3665 carbon dioxide transport, cytoplasm-Golgi membrane carbon dioxide --> carbon dioxide 0.0 r_3665_REV carbon dioxide transport, cytoplasm-Golgi membrane (reversible) carbon dioxide --> carbon dioxide 0.0 r_3666 ATP transport, cytoplasm-Golgi membrane ATP --> ATP 0.0 @@ -4953,14 +4953,14 @@ r_3667_REV ADP transport, cytoplasm-Golgi membrane (reversible) ADP --> ADP 0.0 r_3668 H2O transport, cytoplasm-mitochondrial membrane H2O --> H2O 0.0020585366151649356 r_3668_REV H2O transport, cytoplasm-mitochondrial membrane (reversible) H2O --> H2O 0.0 r_3669 carbon dioxide transport, cytoplasm-mitochondrial membrane carbon dioxide --> carbon dioxide 0.0 -r_3669_REV carbon dioxide transport, cytoplasm-mitochondrial membrane (reversible) carbon dioxide --> carbon dioxide 0.004479956613195266 +r_3669_REV carbon dioxide transport, cytoplasm-mitochondrial membrane (reversible) carbon dioxide --> carbon dioxide 0.0044799566128996245 r_3670 palmitoleoyl-CoA transport, cytoplasm-mitochondrial membrane palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3670_REV palmitoleoyl-CoA transport, cytoplasm-mitochondrial membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3671 oleoyl-CoA transport, cytoplasm-mitochondrial membrane oleoyl-CoA --> oleoyl-CoA 0.0 r_3671_REV oleoyl-CoA transport, cytoplasm-mitochondrial membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.0 r_3672 diglyceride (1-16:0, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3672_REV diglyceride (1-16:0, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3673 diglyceride (1-16:1, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0008362844722709401 +r_3673 diglyceride (1-16:1, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0008362844722709413 r_3673_REV diglyceride (1-16:1, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3674 diglyceride (1-18:0, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3674_REV diglyceride (1-18:0, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 @@ -4968,7 +4968,7 @@ r_3675 diglyceride (1-18:1, 2-16:1) transport, mitochondrial membrane-cytoplasm r_3675_REV diglyceride (1-18:1, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3676 diglyceride (1-16:0, 2-18:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3676_REV diglyceride (1-16:0, 2-18:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 -r_3677 diglyceride (1-16:1, 2-18:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.00019298383531152772 +r_3677 diglyceride (1-16:1, 2-18:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.00019298383531152655 r_3677_REV diglyceride (1-16:1, 2-18:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3678 palmitate transport, mitochondrial membrane-cytoplasm palmitate --> palmitate 0.0 r_3678_REV palmitate transport, mitochondrial membrane-cytoplasm (reversible) palmitate --> palmitate 0.0 @@ -4976,9 +4976,9 @@ r_3679 stearate transport, mitochondrial membrane-cytoplasm stearate --> stearat r_3679_REV stearate transport, mitochondrial membrane-cytoplasm (reversible) stearate --> stearate 0.0 r_3680 coenzyme A transport, mitochondrial membrane-cytoplasm 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.0 r_3680_REV coenzyme A transport, mitochondrial membrane-cytoplasm (reversible) 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.0 -r_3681 laurate transport, ER membrane-lipid particle laurate --> laurate 0.0 +r_3681 laurate transport, ER membrane-lipid particle laurate --> laurate 0.00044172356996047285 r_3681_REV laurate transport, ER membrane-lipid particle (reversible) laurate --> laurate 0.0 -r_3682 myristate transport, ER membrane-lipid particle myristate --> myristate 0.00025539365650321597 +r_3682 myristate transport, ER membrane-lipid particle myristate --> myristate 0.00025539366341234895 r_3682_REV myristate transport, ER membrane-lipid particle (reversible) myristate --> myristate 0.0 r_3683 lignoceric acid transport, ER membrane-lipid particle lignoceric acid --> lignoceric acid 0.0 r_3683_REV lignoceric acid transport, ER membrane-lipid particle (reversible) lignoceric acid --> lignoceric acid 0.0 @@ -4994,10 +4994,10 @@ r_3688 TAG (1-16:0, 2-16:1, 3-18:1) transport, ER membrane-lipid particle trigly r_3688_REV TAG (1-16:0, 2-16:1, 3-18:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:0, 2-16:1, 3-18:1) --> triglyceride (1-16:0, 2-16:1, 3-18:1) 0.0 r_3689 TAG (1-16:1, 2-16:1, 3-16:0) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-16:0) --> triglyceride (1-16:1, 2-16:1, 3-16:0) 0.0 r_3689_REV TAG (1-16:1, 2-16:1, 3-16:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-16:0) --> triglyceride (1-16:1, 2-16:1, 3-16:0) 0.0 -r_3690 TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0005472067037335731 +r_3690 TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_3690_REV TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_3691 TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 -r_3691_REV TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 +r_3691_REV TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0005189749331324809 r_3692 TAG (1-16:1, 2-16:1, 3-18:1) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-18:1) --> triglyceride (1-16:1, 2-16:1, 3-18:1) 0.0 r_3692_REV TAG (1-16:1, 2-16:1, 3-18:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-18:1) --> triglyceride (1-16:1, 2-16:1, 3-18:1) 0.0 r_3693 TAG (1-18:0, 2-16:1, 3-16:0) transport, ER membrane-lipid particle triglyceride (1-18:0, 2-16:1, 3-16:0) --> triglyceride (1-18:0, 2-16:1, 3-16:0) 0.0 @@ -5018,7 +5018,7 @@ r_3700 TAG (1-18:1, 2-16:1, 3-18:1) transport, ER membrane-lipid particle trigly r_3700_REV TAG (1-18:1, 2-16:1, 3-18:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-18:1, 2-16:1, 3-18:1) --> triglyceride (1-18:1, 2-16:1, 3-18:1) 0.0 r_3701 TAG (1-16:0, 2-18:1, 3-16:0) transport, ER membrane-lipid particle triglyceride (1-16:0, 2-18:1, 3-16:0) --> triglyceride (1-16:0, 2-18:1, 3-16:0) 0.0 r_3701_REV TAG (1-16:0, 2-18:1, 3-16:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:0, 2-18:1, 3-16:0) --> triglyceride (1-16:0, 2-18:1, 3-16:0) 0.0 -r_3702 TAG (1-16:0, 2-18:1, 3-16:1) transport, ER membrane-lipid particle triglyceride (1-16:0, 2-18:1, 3-16:1) --> triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 +r_3702 TAG (1-16:0, 2-18:1, 3-16:1) transport, ER membrane-lipid particle triglyceride (1-16:0, 2-18:1, 3-16:1) --> triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0005472083134696547 r_3702_REV TAG (1-16:0, 2-18:1, 3-16:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:0, 2-18:1, 3-16:1) --> triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 r_3703 TAG (1-16:0, 2-18:1, 3-18:0) transport, ER membrane-lipid particle triglyceride (1-16:0, 2-18:1, 3-18:0) --> triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 r_3703_REV TAG (1-16:0, 2-18:1, 3-18:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:0, 2-18:1, 3-18:0) --> triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 @@ -5128,13 +5128,13 @@ r_3755 phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane phos r_3755_REV phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3756 phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3756_REV phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.00027766980278451256 +r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0002776698027845441 r_3757_REV phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 r_3758 phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3758_REV phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3759 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 r_3759_REV phosphatidate (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 -r_3760 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0008362844722709401 +r_3760 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0008362844722709413 r_3760_REV phosphatidate (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3761 phosphatidate (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3761_REV phosphatidate (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 @@ -5142,7 +5142,7 @@ r_3762 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membr r_3762_REV phosphatidate (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3763 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3763_REV phosphatidate (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 -r_3764 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.00019298383531152772 +r_3764 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.00019298383531152655 r_3764_REV phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3765 phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:0, 2-16:1) --> phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 r_3765_REV phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-16:1) --> phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 @@ -5150,7 +5150,7 @@ r_3766 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-mitochondri r_3766_REV phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:1, 2-16:1) --> phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0 r_3767 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 r_3767_REV phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_3768 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0034727008628694335 +r_3768 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0034727008625737923 r_3768_REV phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0 r_3769 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 r_3769_REV phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 @@ -5166,7 +5166,7 @@ r_3774 phosphatidylethanolamine (1-16:1, 2-16:1) transport, mitochondrial membra r_3774_REV phosphatidylethanolamine (1-16:1, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:1, 2-16:1) --> phosphatidylethanolamine (1-16:1, 2-16:1) 0.0 r_3775 phosphatidylethanolamine (1-18:0, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 r_3775_REV phosphatidylethanolamine (1-18:0, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_3776 phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0034727008628694335 +r_3776 phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0034727008625737945 r_3776_REV phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0 r_3777 phosphatidylethanolamine (1-16:0, 2-18:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_3777_REV phosphatidylethanolamine (1-16:0, 2-18:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 @@ -5176,24 +5176,24 @@ r_3779 phosphatidylethanolamine (1-18:0, 2-18:1) transport, mitochondrial membra r_3779_REV phosphatidylethanolamine (1-18:0, 2-18:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:0, 2-18:1) --> phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 r_3780 phosphatidylethanolamine (1-18:1, 2-18:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-18:1) --> phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 r_3780_REV phosphatidylethanolamine (1-18:1, 2-18:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:1, 2-18:1) --> phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 -r_3781 phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:0, 2-16:1) --> phosphatidylcholine (1-16:0, 2-16:1) 0.0001489605715715831 +r_3781 phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:0, 2-16:1) --> phosphatidylcholine (1-16:0, 2-16:1) 0.0001489606695512331 r_3781_REV phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:0, 2-16:1) --> phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_3782 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0 -r_3782_REV phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.00014896057157158318 +r_3782_REV phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0001489606695512331 r_3783 phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_3783_REV phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_3784 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_3784_REV phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_3785 phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 -r_3785_REV phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.00014896057157158318 -r_3786 phosphatidylcholine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:1, 2-18:1) --> phosphatidylcholine (1-16:1, 2-18:1) 0.00014896057157158318 +r_3785_REV phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0001489606695512331 +r_3786 phosphatidylcholine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:1, 2-18:1) --> phosphatidylcholine (1-16:1, 2-18:1) 0.0001489606695512331 r_3786_REV phosphatidylcholine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:1, 2-18:1) --> phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_3787 phosphatidylcholine (1-18:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:0, 2-18:1) --> phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_3787_REV phosphatidylcholine (1-18:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:0, 2-18:1) --> phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_3788 phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:1, 2-18:1) --> phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_3788_REV phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:1, 2-18:1) --> phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_3789 diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3789_REV diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.002394439425894307 +r_3789_REV diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.002394439523657025 r_3790 diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3790_REV diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3791 diglyceride (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 @@ -5203,12 +5203,12 @@ r_3792_REV diglyceride (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane (r r_3793 diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3793_REV diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3794 diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 -r_3794_REV diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0007565683704506696 +r_3794_REV diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0007565683703719278 r_3795 diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 -r_3795_REV diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.00027766980278451256 +r_3795_REV diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0002776698027845441 r_3796 diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 r_3796_REV diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 -r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.002394439425894307 +r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.002394439523657025 r_3797_REV phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 r_3798 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3798_REV phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 @@ -5218,9 +5218,9 @@ r_3800 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane phos r_3800_REV phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3801 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3801_REV phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 -r_3802 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0007565683704506696 +r_3802 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0007565683703719278 r_3802_REV phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.00027766980278451256 +r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0002776698027845441 r_3803_REV phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 r_3804 phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3804_REV phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 @@ -5386,11 +5386,11 @@ r_3876 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, ER membrane-ce r_3876_REV 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, ER membrane-cell envelope (reversible) 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) 0.0 r_3877 phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:0, 2-16:1) --> phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_3877_REV phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:0, 2-16:1) --> phosphatidylcholine (1-16:0, 2-16:1) 0.0 -r_3878 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.00014896057157158318 +r_3878 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0001489606695512331 r_3878_REV phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_3879 phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_3879_REV phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 -r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0034727008628694335 +r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0034727008625737923 r_3880_REV phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_3881 phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_3881_REV phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 @@ -5438,11 +5438,11 @@ r_3902 cerotic acid transport, cell envelope-ER membrane cerotic acid --> ceroti r_3902_REV cerotic acid transport, cell envelope-ER membrane (reversible) cerotic acid --> cerotic acid 0.0 r_3903 phosphatidate (1-16:0, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 r_3903_REV phosphatidate (1-16:0, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 -r_3904 phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.00014896057157158318 +r_3904 phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0001489606695512331 r_3904_REV phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3905 phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3905_REV phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 -r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0034727008628694335 +r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0034727008625737923 r_3906_REV phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3907 phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3907_REV phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 @@ -5544,7 +5544,7 @@ r_3955_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) tran r_3956 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cell envelope 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 r_3956_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cell envelope (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 r_3957 H+ transport, mitochondrion-mitochondrial membrane H+ --> H+ 0.0 -r_3957_REV H+ transport, mitochondrion-mitochondrial membrane (reversible) H+ --> H+ 0.0030878049227474036 +r_3957_REV H+ transport, mitochondrion-mitochondrial membrane (reversible) H+ --> H+ 0.003087804922747403 r_3958 glycerol 3-phosphate transport, mitochondrion-mitochondrial membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3958_REV glycerol 3-phosphate transport, mitochondrion-mitochondrial membrane (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3959 CMP transport, mitochondrion-mitochondrial membrane 0.2701553629071786 prot_P38127 + CMP --> CMP 0.0 @@ -5561,20 +5561,20 @@ r_3963 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) [cytoplasm] SLIME rxn 1-p r_3964 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) --> 0.807012462 1-phosphatidyl-1D-myo-inositol backbone + 0.508826 C16:1 chain 0.0 r_3965 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_3966 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_3967 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0007588092365482631 -r_3968 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 6.687417754955684e-05 +r_3967 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0007588092039423592 +r_3968 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 6.687421023417254e-05 r_3969 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> 0.865135862 1-phosphatidyl-1D-myo-inositol backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_3970 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> 0.863119982 1-phosphatidyl-1D-myo-inositol backbone + 0.56493352 C18:1 chain 0.0 r_3971 ergosteryl palmitoleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl palmitoleate --> 0.63305448 ergosterol ester backbone + 0.254413 C16:1 chain 0.0 r_3972 ergosteryl oleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl oleate --> 0.66110824 ergosterol ester backbone + 0.28246676 C18:1 chain 0.0010294532200153638 r_3973 ergosterol ester transport, ER membrane-cytoplasm ergosterol ester backbone --> ergosterol ester backbone 0.00068058000644669 r_3973_REV ergosterol ester transport, ER membrane-cytoplasm (reversible) ergosterol ester backbone --> ergosterol ester backbone 0.0 -r_3975 palmitate [cytoplasm] SLIME rxn H+ + palmitate --> 0.25542094 fatty acid backbone + 0.25642888 C16:0 chain 1.1847279353553024e-12 -r_3976 palmitoleate [cytoplasm] SLIME rxn H+ + palmitoleate --> 0.25340506 fatty acid backbone + 0.254413 C16:1 chain 0.0005840846218859666 +r_3975 palmitate [cytoplasm] SLIME rxn H+ + palmitate --> 0.25542094 fatty acid backbone + 0.25642888 C16:0 chain -5.50461821821254e-12 +r_3976 palmitoleate [cytoplasm] SLIME rxn H+ + palmitoleate --> 0.25340506 fatty acid backbone + 0.254413 C16:1 chain 0.0005840846286285276 r_3977 stearate [cytoplasm] SLIME rxn H+ + stearate --> 0.2834747 fatty acid backbone + 0.28448264 C18:0 chain 0.0 r_3978 oleate [cytoplasm] SLIME rxn H+ + oleate --> 0.28145882 fatty acid backbone + 0.28246676 C18:1 chain 0.0 -r_3979 phosphatidyl-L-serine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:0, 2-16:1) --> 0.733964182 phosphatidyl-L-serine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 5.846746774310264e-11 -r_3980 phosphatidyl-L-serine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:1, 2-16:1) --> 0.731948302 phosphatidyl-L-serine backbone + 0.508826 C16:1 chain 0.000813008206209888 +r_3979 phosphatidyl-L-serine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:0, 2-16:1) --> 0.733964182 phosphatidyl-L-serine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0 +r_3980 phosphatidyl-L-serine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:1, 2-16:1) --> 0.731948302 phosphatidyl-L-serine backbone + 0.508826 C16:1 chain 0.0008130082648676773 r_3981 phosphatidyl-L-serine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:0, 2-16:1) --> 0.762017942 phosphatidyl-L-serine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_3982 phosphatidyl-L-serine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:1, 2-16:1) --> 0.760002062 phosphatidyl-L-serine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_3983 phosphatidyl-L-serine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:0, 2-18:1) --> 0.762017942 phosphatidyl-L-serine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5583,13 +5583,13 @@ r_3985 phosphatidyl-L-serine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] S r_3986 phosphatidyl-L-serine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:1, 2-18:1) --> 0.788055822 phosphatidyl-L-serine backbone + 0.56493352 C18:1 chain 0.0 r_3987 phosphatidyl-L-serine transport, ER membrane-cytoplasm phosphatidyl-L-serine backbone --> phosphatidyl-L-serine backbone 0.000595080018974841 r_3987_REV phosphatidyl-L-serine transport, ER membrane-cytoplasm (reversible) phosphatidyl-L-serine backbone --> phosphatidyl-L-serine backbone 0.0 -r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-16:1) --> 0.732035022 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.002245478854322724 +r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-16:1) --> 0.732035022 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0022454788541057917 r_3989 phosphatidylcholine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-16:1) --> 0.730019142 phosphatidylcholine backbone + 0.508826 C16:1 chain 0.0 r_3990 phosphatidylcholine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-16:1) --> 0.744089382 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_3991 phosphatidylcholine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-16:1) --> 0.742073502 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-18:1) --> 0.760088782 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.00014896057157158318 -r_3993 phosphatidylcholine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-18:1) --> 0.758072902 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0008005916341906141 -r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-18:1) --> 0.772143142 phosphatidylcholine backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.00027766980276626056 +r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-18:1) --> 0.760088782 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0001489606695512331 +r_3993 phosphatidylcholine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-18:1) --> 0.758072902 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0008005915361322211 +r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-18:1) --> 0.772143142 phosphatidylcholine backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0002776698027934315 r_3995 phosphatidylcholine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-18:1) --> 0.770127262 phosphatidylcholine backbone + 0.56493352 C18:1 chain 0.0 r_3996 phosphatidylcholine transport, ER membrane-cytoplasm phosphatidylcholine backbone --> phosphatidylcholine backbone 0.0025783000793308 r_3996_REV phosphatidylcholine transport, ER membrane-cytoplasm (reversible) phosphatidylcholine backbone --> phosphatidylcholine backbone 0.0 @@ -5613,7 +5613,7 @@ r_4012 triglyceride (1-18:1, 2-16:1, 3-16:0) [endoplasmic reticulum membrane] SL r_4013 triglyceride (1-18:1, 2-18:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-16:0) --> 0.85941128 triglyceride backbone + 0.25642888 C16:0 chain + 0.56493352 C18:1 chain 0.0 r_4014 triglyceride (1-16:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-16:1) --> 0.80330376 triglyceride backbone + 0.25642888 C16:0 chain + 0.508826 C16:1 chain 0.0 r_4015 triglyceride (1-16:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-18:1, 3-16:1) --> 0.83135752 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-16:1) --> 0.80128788 triglyceride backbone + 0.763239 C16:1 chain 0.00031730953913842796 +r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-16:1) --> 0.80128788 triglyceride backbone + 0.763239 C16:1 chain 0.0003173095391384605 r_4017 triglyceride (1-16:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-18:1, 3-16:1) --> 0.82934164 triglyceride backbone + 0.508826 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_4018 triglyceride (1-18:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-16:1, 3-16:1) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_4019 triglyceride (1-18:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-18:1, 3-16:1) --> 0.85941128 triglyceride backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5621,7 +5621,7 @@ r_4020 triglyceride (1-18:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SL r_4021 triglyceride (1-18:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-16:1) --> 0.8573954 triglyceride backbone + 0.254413 C16:1 chain + 0.56493352 C18:1 chain 0.0 r_4022 triglyceride (1-16:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-18:0) --> 0.8333734 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_4023 triglyceride (1-16:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-18:1, 3-18:0) --> 0.86142716 triglyceride backbone + 0.25642888 C16:0 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 -r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-18:0) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0005189749331325122 +r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-18:0) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0005189749331324809 r_4025 triglyceride (1-16:1, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-18:1, 3-18:0) --> 0.85941128 triglyceride backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_4026 triglyceride (1-18:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-16:1, 3-18:0) --> 0.86142716 triglyceride backbone + 0.254413 C16:1 chain + 0.56896528 C18:0 chain 0.0 r_4027 triglyceride (1-18:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-18:1, 3-18:0) --> 0.88948092 triglyceride backbone + 0.56896528 C18:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5637,7 +5637,7 @@ r_4036 triglyceride (1-18:1, 2-16:1, 3-18:1) [endoplasmic reticulum membrane] SL r_4037 triglyceride (1-18:1, 2-18:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-18:1) --> 0.88544916 triglyceride backbone + 0.84740028 C18:1 chain 0.0 r_4038 triglyceride transport, ER membrane-cytoplasm triglyceride backbone --> triglyceride backbone 0.0006857100012712191 r_4038_REV triglyceride transport, ER membrane-cytoplasm (reversible) triglyceride backbone --> triglyceride backbone 0.0 -r_4039 succinyl-CoA:acetate CoA transferase 2.0420759036703515 prot_P32316 + acetate + succinyl-CoA --> acetyl-CoA + succinate 1.4169580512683144 +r_4039 succinyl-CoA:acetate CoA transferase 2.0420759036703515 prot_P32316 + acetate + succinyl-CoA --> acetyl-CoA + succinate 0.11825411901010943 r_4039_REV succinyl-CoA:acetate CoA transferase (reversible) 2.24640342822161 prot_P32316 + acetyl-CoA + succinate --> acetate + succinyl-CoA 0.0 r_4040 heme a transport heme a --> heme a 0.0 r_4040_REV heme a transport (reversible) heme a --> heme a 0.0 @@ -5646,7 +5646,7 @@ r_4042 raffinose invertase 0.3719983416252073 prot_standard + H2O + raffinose -- r_4043 raffinose exchange raffinose --> 0.0 r_4044 melibiose exchange melibiose --> 0.0 r_4045 uridine hydrolase 0.5272222222222223 prot_Q04179 + H2O + uridine --> D-ribose + uracil 0.0 -r_4046 non-growth associated maintenance reaction ATP + H2O --> ADP + H+ + phosphate 4.856691267112488 +r_4046 non-growth associated maintenance reaction ATP + H2O --> ADP + H+ + phosphate 6.52644110756874 r_4047 protein pseudoreaction 0.347736630768556 Ala-tRNA(Ala) + 0.194296205196944 Arg-tRNA(Arg) + 0.191468067207859 Asn-tRNA(Asn) + 0.240359946744132 Asp-tRNA(Asp) + 0.0375594996568427 Cys-tRNA(Cys) + 0.141160332291015 Gln-tRNA(Gln) + 0.296487312016288 Glu-tRNA(Glu) + 0.283748983111195 Gly-tRNA(Gly) + 0.08356708763266 His-tRNA(His) + 0.265490320174191 Ile-tRNA(Ile) + 0.362523293945085 Leu-tRNA(Leu) + 0.32939964005654 Lys-tRNA(Lys) + 0.0814974664727417 Met-tRNA(Met) + 0.166795958026717 Phe-tRNA(Phe) + 0.179821149401597 Pro-tRNA(Pro) + 0.277725658983052 Ser-tRNA(Ser) + 0.235173028298401 Thr-tRNA(Thr) + 0.0385698144584582 Trp-tRNA(Trp) + 0.123025660792855 Tyr-tRNA(Tyr) + 0.31460454977486 Val-tRNA(Val) --> 4.17785919150305 H+ + 0.347736630768556 tRNA(Ala) + 0.194296205196944 tRNA(Arg) + 0.191468067207859 tRNA(Asn) + 0.240359946744132 tRNA(Asp) + 0.0375594996568427 tRNA(Cys) + 0.141160332291015 tRNA(Gln) + 0.296487312016288 tRNA(Glu) + 0.283748983111195 tRNA(Gly) + 0.08356708763266 tRNA(His) + 0.265490320174191 tRNA(Ile) + 0.362523293945085 tRNA(Leu) + 0.32939964005654 tRNA(Lys) + 0.0814974664727417 tRNA(Met) + 0.166795958026717 tRNA(Phe) + 0.179821149401597 tRNA(Pro) + 0.277725658983052 tRNA(Ser) + 0.235173028298401 tRNA(Thr) + 0.0385698144584582 tRNA(Trp) + 0.123025660792855 tRNA(Tyr) + 0.31460454977486 tRNA(Val) + protein 0.1 r_4048 carbohydrate pseudoreaction 0.73914 (1->3)-beta-D-glucan + 0.24696 (1->6)-beta-D-glucan + 0.02361 chitin + 0.35689 glycogen + 0.70204 mannan + 0.13655 trehalose --> carbohydrate 0.1 r_4049 RNA pseudoreaction 0.0445348319234424 AMP + 0.043276239184487 CMP + 0.0445348319234424 GMP + 0.380675999881061 H+ + 0.0579920969091588 UMP --> RNA 0.1 @@ -6136,7 +6136,7 @@ r_4332 Protein PNS1 (pH nine-sensitive protein 1) 4.890140948879145 prot_Q12412 r_4332_REV Protein PNS1 (pH nine-sensitive protein 1) (reversible) 4.890140948879145 prot_Q12412 + choline --> choline 0.0 r_4333_EXP_1 Polyphosphate phosphohydrolase 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4333_EXP_2 Polyphosphate phosphohydrolase 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 -r_4333_REV_EXP_1 Polyphosphate phosphohydrolase (reversible) 0.008073655913978494 prot_P38698 + H+ + 2.0 phosphate --> H2O + polyphosphate 3.6237211703851107 +r_4333_REV_EXP_1 Polyphosphate phosphohydrolase (reversible) 0.008073655913978494 prot_P38698 + H+ + 2.0 phosphate --> H2O + polyphosphate 4.371390528947714 r_4333_REV_EXP_2 Polyphosphate phosphohydrolase (reversible) 0.014040143369175627 prot_Q04119 + H+ + 2.0 phosphate --> H2O + polyphosphate 1.5368292317990797 r_4334 Copper-transporting ATPase (EC 3.6.3.54) (Cu(2+)-ATPase) 117.33867521367522 prot_P38995 + ATP + H2O + Cu2(+) --> ADP + H+ + phosphate + Cu2(+) 0.0 r_4335 Endopolyphosphatase (EC 3.6.1.10) (Deoxyadenosine triphosphate phosphohydrolase) (dATP phosphohydrolase) (EC 3.6.1.-) (Exopolyphosphatase) (EC 3.6.1.11) (Phosphate metabolism protein 5) 0.014040143369175627 prot_Q04119 + dATP + H2O --> dADP + H+ + phosphate 0.0 @@ -6244,7 +6244,7 @@ r_4395_REV_EXP_6 D-tagatose uptake via diffusion (reversible) 13.684095333659302 r_4395_REV_EXP_7 D-tagatose uptake via diffusion (reversible) 73.03443030411316 prot_P32467 + D-tagatose --> D-tagatose 0.0 r_4395_REV_EXP_8 D-tagatose uptake via diffusion (reversible) 37.00560827252129 prot_P32465 + D-tagatose --> D-tagatose 0.0 r_4395_REV_EXP_9 D-tagatose uptake via diffusion (reversible) 18.403210661257148 prot_P38695 + D-tagatose --> D-tagatose 0.0 -r_4396 Acetoacetate:CoA ligase (AMP-forming) 0.09872642040857446 prot_standard + ATP + coenzyme A + acetoacetate --> acetoacetyl-CoA + AMP + diphosphate 0.010251976559931349 +r_4396 Acetoacetate:CoA ligase (AMP-forming) 0.09872642040857446 prot_standard + ATP + coenzyme A + acetoacetate --> acetoacetyl-CoA + AMP + diphosphate -4.977216555568376e-13 r_4397 N-Acyl-Aliphatic-L-Amino Acid Amidohydrolase 0.9586111111111111 prot_standard + H2O + N(alpha)-acetyl-L-methionine --> acetate + L-methionine 0.0 r_4397_REV N-Acyl-Aliphatic-L-Amino Acid Amidohydrolase (reversible) 0.9586111111111111 prot_standard + acetate + L-methionine --> H2O + N(alpha)-acetyl-L-methionine 0.0 r_4398_EXP_1 Ala-Gln transport via proton symport 1.7459701644404326 prot_P15365 + H+ + Ala-Gln --> H+ + Ala-Gln 0.0 @@ -6383,7 +6383,7 @@ r_4478_REV L-methionine S-oxide transport via diffusion (extracellular) (reversi r_4479 Gly-Asn transport via proton symport H+ + Gly-Asn --> H+ + Gly-Asn 0.0 r_4479_REV Gly-Asn transport via proton symport (reversible) H+ + Gly-Asn --> H+ + Gly-Asn 0.0 r_4480 Cysteamine transport via proton antiport H+ + cysteamine --> H+ + cysteamine 0.0 -r_4481 Hydrogen sulfide oxidation 0.6656659785008318 prot_standard + hydrogen sulfide + 2.0 oxygen --> H+ + sulphate 0.0001192491661360165 +r_4481 Hydrogen sulfide oxidation 0.6656659785008318 prot_standard + hydrogen sulfide + 2.0 oxygen --> H+ + sulphate 0.00011924916621594561 r_4482 L-alanine transport in via proton symport H+ + L-alanine --> H+ + L-alanine 0.0 r_4482_REV L-alanine transport in via proton symport (reversible) H+ + L-alanine --> H+ + L-alanine 0.0 r_4483 Glycine transport (vacuole) H+ + L-glycine --> H+ + L-glycine 0.0 @@ -6394,10 +6394,10 @@ r_4484_EXP_3 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropy r_4484_REV_EXP_1 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) (reversible) 0.16609504132231406 prot_P47164 + L-homocysteine + succinate --> hydrogen sulfide + O-succinyl-L-homoserine 0.0 r_4484_REV_EXP_2 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) (reversible) 11.75934135228728 prot_Q12198 + L-homocysteine + succinate --> hydrogen sulfide + O-succinyl-L-homoserine 0.0 r_4484_REV_EXP_3 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) (reversible) 0.170599173553719 prot_Q04533 + L-homocysteine + succinate --> hydrogen sulfide + O-succinyl-L-homoserine 0.0 -r_4485 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) 1.1329040404040405 prot_standard + 3-(4-hydroxyphenyl)pyruvate + oxygen --> carbon dioxide + homogentisate 0.010251976559931349 -r_4486 Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) 1.1329040404040405 prot_standard + oxygen + homogentisate --> H+ + 4-maleylacetoacetate 0.010251976559931349 -r_4487 4-Maleylacetoacetate cis-trans-isomerase 1.1329040404040405 prot_standard + 4-maleylacetoacetate --> 4-fumarylacetoacetate 0.010251976559931349 -r_4488 4-fumarylacetoacetate fumarylhydrolase 1.1329040404040405 prot_standard + H2O + 4-fumarylacetoacetate --> fumarate + H+ + acetoacetate 0.010251976559931349 +r_4485 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) 1.1329040404040405 prot_standard + 3-(4-hydroxyphenyl)pyruvate + oxygen --> carbon dioxide + homogentisate -4.977216555568376e-13 +r_4486 Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) 1.1329040404040405 prot_standard + oxygen + homogentisate --> H+ + 4-maleylacetoacetate -4.977216555568376e-13 +r_4487 4-Maleylacetoacetate cis-trans-isomerase 1.1329040404040405 prot_standard + 4-maleylacetoacetate --> 4-fumarylacetoacetate -4.977216555568376e-13 +r_4488 4-fumarylacetoacetate fumarylhydrolase 1.1329040404040405 prot_standard + H2O + 4-fumarylacetoacetate --> fumarate + H+ + acetoacetate -4.977216555568376e-13 r_4489 L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming) 1.1329040404040405 prot_standard + L-arabinitol + NAD --> H+ + NADH + L-xylulose 0.0 r_4490 Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) 1.1329040404040405 prot_standard + H+ + NADPH + L-xylulose --> NADP(+) + xylitol 0.0 r_4490_REV Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) (reversible) 1.1329040404040405 prot_standard + NADP(+) + xylitol --> H+ + NADPH + L-xylulose 0.0 @@ -6481,17 +6481,17 @@ r_4567 6-phosphogluconate phosphatase 0.17308256172839506 prot_standard + 6-phos r_4569 Carboxylic ester hydrolases 0.45405614353626883 prot_standard + acetate + H+ + Hydroquinone --> H2O + 4-hydroxyphenyl acetate 0.0 r_4570_EXP_1 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + NAD + 2-hydroxyglutarate --> 2-oxoglutarate + H+ + NADH 0.0 r_4570_EXP_2 phosphoglycerate dehydrogenase 0.0036935786435786434 prot_P40054 + NAD + 2-hydroxyglutarate --> 2-oxoglutarate + H+ + NADH 0.0 -r_4570_REV_EXP_1 phosphoglycerate dehydrogenase (reversible) 0.005777687480247415 prot_P40510 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.022419561056689307 +r_4570_REV_EXP_1 phosphoglycerate dehydrogenase (reversible) 0.005777687480247415 prot_P40510 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.022419561056689297 r_4570_REV_EXP_2 phosphoglycerate dehydrogenase (reversible) 0.0057782518398121815 prot_P40054 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.0 -r_4571 seed:rxn00681 1.1329040404040405 prot_standard + coenzyme A + H+ + 2-hydroxyglutarate --> glyoxylate + H2O + propionyl-CoA 0.022419561056689307 +r_4571 seed:rxn00681 1.1329040404040405 prot_standard + coenzyme A + H+ + 2-hydroxyglutarate --> glyoxylate + H2O + propionyl-CoA 0.022419561056689297 r_4571_REV seed:rxn00681 (reversible) 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + 2-hydroxyglutarate 0.0 -r_4572 beta-alanine:2-oxoglutarate aminotransferase 1.1329040404040405 prot_standard + 2-oxoglutarate + beta-alanine --> L-glutamate + 3-oxopropanoate 0.0013101366952277074 +r_4572 beta-alanine:2-oxoglutarate aminotransferase 1.1329040404040405 prot_standard + 2-oxoglutarate + beta-alanine --> L-glutamate + 3-oxopropanoate 0.0013101366952275786 r_4572_REV beta-alanine:2-oxoglutarate aminotransferase (reversible) 1.1329040404040405 prot_standard + L-glutamate + 3-oxopropanoate --> 2-oxoglutarate + beta-alanine 0.0 r_4573 3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NAD + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADH 0.0 -r_4574 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NADP(+) + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADPH 0.0013101366952277074 +r_4574 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NADP(+) + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADPH 0.0013101366952275786 r_4575 3-oxopropanoate carboxy-lyase 0.45405614353626883 prot_standard + H+ + 3-oxopropanoate --> acetaldehyde + carbon dioxide 0.0 -r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.048490056204063985 prot_standard + NAD + (2R,3S)-3-methylmalate --> 2-oxobutanoate + carbon dioxide + NADH 0.022419561056689307 -r_4582 malate/beta-methylmalate synthase 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + (2R,3S)-3-methylmalate 0.022419561056689307 +r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.048490056204063985 prot_standard + NAD + (2R,3S)-3-methylmalate --> 2-oxobutanoate + carbon dioxide + NADH 0.022419561056689297 +r_4582 malate/beta-methylmalate synthase 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + (2R,3S)-3-methylmalate 0.022419561056689297 r_4583 palmitoyl-CoA hydrolase 2.0068374645606704 prot_standard + H2O + trans-2,cis-9-octadecadienoyl-CoA --> coenzyme A + H+ + (9Z,12Z)-octadecadienoate 0.0 r_4584_EXP_1 long-chain-fatty-acid---CoA ligase 745.8429118773946 prot_P30624 + ATP + coenzyme A + (9Z,12Z)-octadecadienoate --> AMP + diphosphate + trans-2,cis-9-octadecadienoyl-CoA 0.0 r_4584_EXP_2 long-chain-fatty-acid---CoA ligase 799.2145593869732 prot_P39518 + ATP + coenzyme A + (9Z,12Z)-octadecadienoate --> AMP + diphosphate + trans-2,cis-9-octadecadienoyl-CoA 0.0 @@ -6760,7 +6760,7 @@ r_4721_REV ethyl-2-methylbutyrate esterase, c (reversible) 0.1481119020744172 pr r_4722 polyphosphate polymerase, c 0.6242867867867868 prot_P47075 + 2.0 ATP + H2O --> 2.0 ADP + H+ + polyphosphate 0.10856224543938203 r_4723_EXP_1 polyphosphate phosphohydrolase, v 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4723_EXP_2 polyphosphate phosphohydrolase, v 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 -r_4724_EXP_1 polyphosphate phosphohydrolase, m 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 5.2691126476235715 +r_4724_EXP_1 polyphosphate phosphohydrolase, m 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 6.016782006186176 r_4724_EXP_2 polyphosphate phosphohydrolase, m 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4725_EXP_1 polyphosphate phosphohydrolase, n 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4725_EXP_2 polyphosphate phosphohydrolase, n 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 @@ -6793,7 +6793,7 @@ r_4742_REV ethyl-2-methylbutyrate transport (reversible) ethyl 2-methylbutyrate r_4743 ethyl-2-methylbutyrate exchange ethyl 2-methylbutyrate --> 0.0 r_4744 polyphosphate transport, v-c H+ + polyphosphate --> H+ + polyphosphate 0.10856224543938205 r_4744_REV polyphosphate transport, v-c (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 -r_4745 polyphosphate transport, c-m H+ + polyphosphate --> H+ + polyphosphate 5.269112647623572 +r_4745 polyphosphate transport, c-m H+ + polyphosphate --> H+ + polyphosphate 6.016782006186176 r_4745_REV polyphosphate transport, c-m (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4746 polyphosphate transport, c-n H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4746_REV polyphosphate transport, c-n (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 @@ -6855,7 +6855,7 @@ r_4783 oxaloacetate/sulphate antiport, mitochondrial 0.8569958862601018 prot_P32 r_4783_REV oxaloacetate/sulphate antiport, mitochondrial (reversible) 0.8569958862601018 prot_P32332 + oxaloacetate + sulphate --> oxaloacetate + sulphate 0.0 r_4784 malate/sulphate antiport, mitochondrial 0.645505273974352 prot_P32332 + (S)-malate + sulphate --> (S)-malate + sulphate 0.0 r_4784_REV malate/sulphate antiport, mitochondrial (reversible) 0.645505273974352 prot_P32332 + (S)-malate + sulphate --> (S)-malate + sulphate 0.0 -r_4785 acetate transport acetate --> acetate 0.10227709039704025 +r_4785 acetate transport acetate --> acetate 0.07334377129427377 r_4786_EXP_1 ribonucleotide reductase 2.143863049095607 prot_P21524 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 r_4786_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0006000000052154061 r_4786_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 @@ -6865,56 +6865,56 @@ r_4787_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + H+ + UDP + r_4787_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 r_4787_EXP_4 ribonucleotide reductase 0.9936907838070629 prot_P09938 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 usage_prot_O13525 usage_prot_O13525 prot_pool --> prot_O13525 0.0 -usage_prot_P00044 usage_prot_P00044 prot_pool --> prot_P00044 0.06899111139564522 -usage_prot_P00045 usage_prot_P00045 prot_pool --> prot_P00045 0.0514348774661771 -usage_prot_P00127 usage_prot_P00127 prot_pool --> prot_P00127 0.15985627766025262 -usage_prot_P00128 usage_prot_P00128 prot_pool --> prot_P00128 0.13491955056623856 -usage_prot_P00163 usage_prot_P00163 prot_pool --> prot_P00163 0.40439738410708626 -usage_prot_P00175 usage_prot_P00175 prot_pool --> prot_P00175 0.001259714161262884 -usage_prot_P00330 usage_prot_P00330 prot_pool --> prot_P00330 0.008494608019371117 +usage_prot_P00044 usage_prot_P00044 prot_pool --> prot_P00044 0.07044811038901563 +usage_prot_P00045 usage_prot_P00045 prot_pool --> prot_P00045 0.0 +usage_prot_P00127 usage_prot_P00127 prot_pool --> prot_P00127 0.03196157710971142 +usage_prot_P00128 usage_prot_P00128 prot_pool --> prot_P00128 0.0269757414731962 +usage_prot_P00163 usage_prot_P00163 prot_pool --> prot_P00163 0.0808549927740373 +usage_prot_P00175 usage_prot_P00175 prot_pool --> prot_P00175 0.0012597141607482891 +usage_prot_P00330 usage_prot_P00330 prot_pool --> prot_P00330 0.008492656428157672 usage_prot_P00331 usage_prot_P00331 prot_pool --> prot_P00331 0.0 -usage_prot_P00358 usage_prot_P00358 prot_pool --> prot_P00358 0.159256816859232 +usage_prot_P00358 usage_prot_P00358 prot_pool --> prot_P00358 0.13966203476294622 usage_prot_P00359 usage_prot_P00359 prot_pool --> prot_P00359 0.0 usage_prot_P00360 usage_prot_P00360 prot_pool --> prot_P00360 0.48190382666954507 -usage_prot_P00401 usage_prot_P00401 prot_pool --> prot_P00401 0.23052565723082274 -usage_prot_P00410 usage_prot_P00410 prot_pool --> prot_P00410 0.11200085802430206 -usage_prot_P00420 usage_prot_P00420 prot_pool --> prot_P00420 0.11903056147365179 -usage_prot_P00424 usage_prot_P00424 prot_pool --> prot_P00424 0.008315569285267716 +usage_prot_P00401 usage_prot_P00401 prot_pool --> prot_P00401 0.0982814425689462 +usage_prot_P00410 usage_prot_P00410 prot_pool --> prot_P00410 0.04775002499858986 +usage_prot_P00420 usage_prot_P00420 prot_pool --> prot_P00420 0.05074704235506662 +usage_prot_P00424 usage_prot_P00424 prot_pool --> prot_P00424 0.028649680697162117 usage_prot_P00425 usage_prot_P00425 prot_pool --> prot_P00425 0.0 -usage_prot_P00427 usage_prot_P00427 prot_pool --> prot_P00427 0.00841357074358884 +usage_prot_P00427 usage_prot_P00427 prot_pool --> prot_P00427 0.028987325708878964 usage_prot_P00431 usage_prot_P00431 prot_pool --> prot_P00431 0.0 usage_prot_P00445 usage_prot_P00445 prot_pool --> prot_P00445 0.0 usage_prot_P00447 usage_prot_P00447 prot_pool --> prot_P00447 0.0 usage_prot_P00498 usage_prot_P00498 prot_pool --> prot_P00498 0.0069351225554408645 -usage_prot_P00549 usage_prot_P00549 prot_pool --> prot_P00549 0.20759493243771845 -usage_prot_P00560 usage_prot_P00560 prot_pool --> prot_P00560 0.08495462797055633 +usage_prot_P00549 usage_prot_P00549 prot_pool --> prot_P00549 0.20678779440607023 +usage_prot_P00560 usage_prot_P00560 prot_pool --> prot_P00560 0.08419369033699069 usage_prot_P00572 usage_prot_P00572 prot_pool --> prot_P00572 0.0 usage_prot_P00635 usage_prot_P00635 prot_pool --> prot_P00635 0.0 usage_prot_P00724 usage_prot_P00724 prot_pool --> prot_P00724 0.0 usage_prot_P00812 usage_prot_P00812 prot_pool --> prot_P00812 0.0 usage_prot_P00815 usage_prot_P00815 prot_pool --> prot_P00815 0.06105817814264418 -usage_prot_P00817 usage_prot_P00817 prot_pool --> prot_P00817 0.03701244418952779 -usage_prot_P00830 usage_prot_P00830 prot_pool --> prot_P00830 6.297315417403474 -usage_prot_P00854 usage_prot_P00854 prot_pool --> prot_P00854 1.1147545432652217 -usage_prot_P00856 usage_prot_P00856 prot_pool --> prot_P00856 0.22303518852503937 -usage_prot_P00890 usage_prot_P00890 prot_pool --> prot_P00890 0.16211773021895634 -usage_prot_P00899 usage_prot_P00899 prot_pool --> prot_P00899 0.0005100871549317087 -usage_prot_P00912 usage_prot_P00912 prot_pool --> prot_P00912 0.00043822927393458833 -usage_prot_P00924 usage_prot_P00924 prot_pool --> prot_P00924 0.1846704057332169 +usage_prot_P00817 usage_prot_P00817 prot_pool --> prot_P00817 0.03417990908988982 +usage_prot_P00830 usage_prot_P00830 prot_pool --> prot_P00830 0.33421139164380625 +usage_prot_P00854 usage_prot_P00854 prot_pool --> prot_P00854 0.05916230052830066 +usage_prot_P00856 usage_prot_P00856 prot_pool --> prot_P00856 0.011836933010610893 +usage_prot_P00890 usage_prot_P00890 prot_pool --> prot_P00890 0.16247620409192515 +usage_prot_P00899 usage_prot_P00899 prot_pool --> prot_P00899 0.000510087154931553 +usage_prot_P00912 usage_prot_P00912 prot_pool --> prot_P00912 0.000438229273934602 +usage_prot_P00924 usage_prot_P00924 prot_pool --> prot_P00924 0.18281229940685834 usage_prot_P00925 usage_prot_P00925 prot_pool --> prot_P00925 0.0 usage_prot_P00927 usage_prot_P00927 prot_pool --> prot_P00927 0.0 -usage_prot_P00931 usage_prot_P00931 prot_pool --> prot_P00931 0.0019463070778026315 -usage_prot_P00937 usage_prot_P00937 prot_pool --> prot_P00937 0.0074701813062283 -usage_prot_P00942 usage_prot_P00942 prot_pool --> prot_P00942 0.0015504189231771242 -usage_prot_P00950 usage_prot_P00950 prot_pool --> prot_P00950 0.043486957930097235 +usage_prot_P00931 usage_prot_P00931 prot_pool --> prot_P00931 0.0019463070778026922 +usage_prot_P00937 usage_prot_P00937 prot_pool --> prot_P00937 0.007470181306228371 +usage_prot_P00942 usage_prot_P00942 prot_pool --> prot_P00942 0.0015133734027319749 +usage_prot_P00950 usage_prot_P00950 prot_pool --> prot_P00950 0.04304940329689447 usage_prot_P00958 usage_prot_P00958 prot_pool --> prot_P00958 0.007758377702723959 -usage_prot_P03962 usage_prot_P03962 prot_pool --> prot_P03962 0.0001528521515060032 +usage_prot_P03962 usage_prot_P03962 prot_pool --> prot_P03962 0.00015285215150600325 usage_prot_P03965 usage_prot_P03965 prot_pool --> prot_P03965 0.0 -usage_prot_P04037 usage_prot_P04037 prot_pool --> prot_P04037 0.008317024752470505 -usage_prot_P04039 usage_prot_P04039 prot_pool --> prot_P04039 0.004321282125080487 -usage_prot_P04046 usage_prot_P04046 prot_pool --> prot_P04046 0.0029018122709108473 +usage_prot_P04037 usage_prot_P04037 prot_pool --> prot_P04037 0.0286546952270391 +usage_prot_P04039 usage_prot_P04039 prot_pool --> prot_P04039 0.014888139204762134 +usage_prot_P04046 usage_prot_P04046 prot_pool --> prot_P04046 0.0029018122709812202 usage_prot_P04076 usage_prot_P04076 prot_pool --> prot_P04076 9.576474603701102e-05 -usage_prot_P04161 usage_prot_P04161 prot_pool --> prot_P04161 0.0016740252577013958 +usage_prot_P04161 usage_prot_P04161 prot_pool --> prot_P04161 0.001674025257741993 usage_prot_P04173 usage_prot_P04173 prot_pool --> prot_P04173 0.002406504749325647 usage_prot_P04385 usage_prot_P04385 prot_pool --> prot_P04385 0.0 usage_prot_P04397 usage_prot_P04397 prot_pool --> prot_P04397 0.0 @@ -6929,18 +6929,18 @@ usage_prot_P05030 usage_prot_P05030 prot_pool --> prot_P05030 0.0 usage_prot_P05150 usage_prot_P05150 prot_pool --> prot_P05150 6.007467226861394e-05 usage_prot_P05316 usage_prot_P05316 prot_pool --> prot_P05316 0.0 usage_prot_P05373 usage_prot_P05373 prot_pool --> prot_P05373 0.0 -usage_prot_P05374 usage_prot_P05374 prot_pool --> prot_P05374 0.5882767901017606 -usage_prot_P05375 usage_prot_P05375 prot_pool --> prot_P05375 0.008530018951356397 -usage_prot_P05626 usage_prot_P05626 prot_pool --> prot_P05626 1.0314707061210382 -usage_prot_P05694 usage_prot_P05694 prot_pool --> prot_P05694 0.5391153829689124 -usage_prot_P06106 usage_prot_P06106 prot_pool --> prot_P06106 0.0016681143322862027 +usage_prot_P05374 usage_prot_P05374 prot_pool --> prot_P05374 0.588276790101759 +usage_prot_P05375 usage_prot_P05375 prot_pool --> prot_P05375 0.008530018950630212 +usage_prot_P05626 usage_prot_P05626 prot_pool --> prot_P05626 0.05474225718150092 +usage_prot_P05694 usage_prot_P05694 prot_pool --> prot_P05694 0.5391153829494139 +usage_prot_P06106 usage_prot_P06106 prot_pool --> prot_P06106 0.0016681143322862235 usage_prot_P06115 usage_prot_P06115 prot_pool --> prot_P06115 0.0 -usage_prot_P06168 usage_prot_P06168 prot_pool --> prot_P06168 0.06349501004238951 -usage_prot_P06169 usage_prot_P06169 prot_pool --> prot_P06169 0.21371203364968364 +usage_prot_P06168 usage_prot_P06168 prot_pool --> prot_P06168 0.0634950100423896 +usage_prot_P06169 usage_prot_P06169 prot_pool --> prot_P06169 0.10919122269176787 usage_prot_P06174 usage_prot_P06174 prot_pool --> prot_P06174 0.0 usage_prot_P06182 usage_prot_P06182 prot_pool --> prot_P06182 0.0 -usage_prot_P06197 usage_prot_P06197 prot_pool --> prot_P06197 0.0008693384417493603 -usage_prot_P06208 usage_prot_P06208 prot_pool --> prot_P06208 0.044243117449195346 +usage_prot_P06197 usage_prot_P06197 prot_pool --> prot_P06197 0.0008693384418322339 +usage_prot_P06208 usage_prot_P06208 prot_pool --> prot_P06208 0.04424311744830373 usage_prot_P06633 usage_prot_P06633 prot_pool --> prot_P06633 3.951695237200766e-05 usage_prot_P06700 usage_prot_P06700 prot_pool --> prot_P06700 0.0 usage_prot_P06738 usage_prot_P06738 prot_pool --> prot_P06738 0.0 @@ -6949,63 +6949,63 @@ usage_prot_P06775 usage_prot_P06775 prot_pool --> prot_P06775 0.0002071093245123 usage_prot_P06776 usage_prot_P06776 prot_pool --> prot_P06776 0.0 usage_prot_P06780 usage_prot_P06780 prot_pool --> prot_P06780 0.0914294990677141 usage_prot_P06785 usage_prot_P06785 prot_pool --> prot_P06785 7.30145820791087e-05 -usage_prot_P07143 usage_prot_P07143 prot_pool --> prot_P07143 0.3154607136651737 -usage_prot_P07149 usage_prot_P07149 prot_pool --> prot_P07149 0.689704670836055 -usage_prot_P07170 usage_prot_P07170 prot_pool --> prot_P07170 0.004279046949155988 +usage_prot_P07143 usage_prot_P07143 prot_pool --> prot_P07143 0.06307304331408833 +usage_prot_P07149 usage_prot_P07149 prot_pool --> prot_P07149 0.6911284291875177 +usage_prot_P07170 usage_prot_P07170 prot_pool --> prot_P07170 0.004357501899066727 usage_prot_P07172 usage_prot_P07172 prot_pool --> prot_P07172 3.193370984930483e-05 usage_prot_P07236 usage_prot_P07236 prot_pool --> prot_P07236 0.0 -usage_prot_P07244 usage_prot_P07244 prot_pool --> prot_P07244 0.06995023953384816 -usage_prot_P07245 usage_prot_P07245 prot_pool --> prot_P07245 1.4142881972243841 +usage_prot_P07244 usage_prot_P07244 prot_pool --> prot_P07244 0.06995023953554455 +usage_prot_P07245 usage_prot_P07245 prot_pool --> prot_P07245 1.414288197223803 usage_prot_P07246 usage_prot_P07246 prot_pool --> prot_P07246 0.0 usage_prot_P07250 usage_prot_P07250 prot_pool --> prot_P07250 0.0 -usage_prot_P07251 usage_prot_P07251 prot_pool --> prot_P07251 6.7356473698430985 -usage_prot_P07255 usage_prot_P07255 prot_pool --> prot_P07255 0.027299400511891874 -usage_prot_P07256 usage_prot_P07256 prot_pool --> prot_P07256 0.46527560493244297 -usage_prot_P07257 usage_prot_P07257 prot_pool --> prot_P07257 0.37495870702507417 +usage_prot_P07251 usage_prot_P07251 prot_pool --> prot_P07251 0.35747456366500346 +usage_prot_P07255 usage_prot_P07255 prot_pool --> prot_P07255 0.011638723844477237 +usage_prot_P07256 usage_prot_P07256 prot_pool --> prot_P07256 0.09302695109616879 +usage_prot_P07257 usage_prot_P07257 prot_pool --> prot_P07257 0.07496903970834436 usage_prot_P07258 usage_prot_P07258 prot_pool --> prot_P07258 0.0 -usage_prot_P07259 usage_prot_P07259 prot_pool --> prot_P07259 0.002079419723508338 -usage_prot_P07262 usage_prot_P07262 prot_pool --> prot_P07262 0.4602667574730036 +usage_prot_P07259 usage_prot_P07259 prot_pool --> prot_P07259 0.002079419723508339 +usage_prot_P07262 usage_prot_P07262 prot_pool --> prot_P07262 0.4602667574728977 usage_prot_P07263 usage_prot_P07263 prot_pool --> prot_P07263 0.0034792344478061566 usage_prot_P07264 usage_prot_P07264 prot_pool --> prot_P07264 0.055714728184709066 usage_prot_P07275 usage_prot_P07275 prot_pool --> prot_P07275 0.0 -usage_prot_P07277 usage_prot_P07277 prot_pool --> prot_P07277 0.01055527005943206 +usage_prot_P07277 usage_prot_P07277 prot_pool --> prot_P07277 0.01055527006023525 usage_prot_P07283 usage_prot_P07283 prot_pool --> prot_P07283 0.028082351315826468 usage_prot_P07284 usage_prot_P07284 prot_pool --> prot_P07284 0.10274415763450748 -usage_prot_P07285 usage_prot_P07285 prot_pool --> prot_P07285 0.01288132192250142 +usage_prot_P07285 usage_prot_P07285 prot_pool --> prot_P07285 0.012881321922501823 usage_prot_P07286 usage_prot_P07286 prot_pool --> prot_P07286 0.0 -usage_prot_P07342 usage_prot_P07342 prot_pool --> prot_P07342 0.006561142598005428 +usage_prot_P07342 usage_prot_P07342 prot_pool --> prot_P07342 0.006561142598005438 usage_prot_P07347 usage_prot_P07347 prot_pool --> prot_P07347 0.0 usage_prot_P07702 usage_prot_P07702 prot_pool --> prot_P07702 0.034086674982829246 usage_prot_P07806 usage_prot_P07806 prot_pool --> prot_P07806 0.02198211901399119 -usage_prot_P07807 usage_prot_P07807 prot_pool --> prot_P07807 1.1324891177556679e-05 +usage_prot_P07807 usage_prot_P07807 prot_pool --> prot_P07807 1.1324891177558395e-05 usage_prot_P07991 usage_prot_P07991 prot_pool --> prot_P07991 0.004175463725398881 usage_prot_P08004 usage_prot_P08004 prot_pool --> prot_P08004 0.0 usage_prot_P08019 usage_prot_P08019 prot_pool --> prot_P08019 0.0 -usage_prot_P08067 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prot_pool --> prot_P25372 0.0 usage_prot_P25373 usage_prot_P25373 prot_pool --> prot_P25373 3.432416924587133e-05 usage_prot_P25376 usage_prot_P25376 prot_pool --> prot_P25376 0.0 usage_prot_P25377 usage_prot_P25377 prot_pool --> prot_P25377 0.0 -usage_prot_P25379 usage_prot_P25379 prot_pool --> prot_P25379 2.736346751191086e-06 +usage_prot_P25379 usage_prot_P25379 prot_pool --> prot_P25379 2.736346751190202e-06 usage_prot_P25515 usage_prot_P25515 prot_pool --> prot_P25515 0.0 usage_prot_P25568 usage_prot_P25568 prot_pool --> prot_P25568 0.0 usage_prot_P25576 usage_prot_P25576 prot_pool --> prot_P25576 0.0 @@ -7185,64 +7185,64 @@ usage_prot_P25621 usage_prot_P25621 prot_pool --> prot_P25621 0.0 usage_prot_P25628 usage_prot_P25628 prot_pool --> prot_P25628 0.002122137174399538 usage_prot_P25641 usage_prot_P25641 prot_pool --> prot_P25641 0.0 usage_prot_P26263 usage_prot_P26263 prot_pool --> prot_P26263 0.0 -usage_prot_P26364 usage_prot_P26364 prot_pool --> prot_P26364 0.7398143217495885 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usage_prot_P28239 prot_pool --> prot_P28239 0.0 +usage_prot_P28239 usage_prot_P28239 prot_pool --> prot_P28239 0.0035087856737464904 usage_prot_P28240 usage_prot_P28240 prot_pool --> prot_P28240 0.0 -usage_prot_P28241 usage_prot_P28241 prot_pool --> prot_P28241 0.0 -usage_prot_P28272 usage_prot_P28272 prot_pool --> prot_P28272 0.012199494660816924 +usage_prot_P28241 usage_prot_P28241 prot_pool --> prot_P28241 0.032803241549709955 +usage_prot_P28272 usage_prot_P28272 prot_pool --> prot_P28272 0.012199494660816927 usage_prot_P28273 usage_prot_P28273 prot_pool --> prot_P28273 0.0 usage_prot_P28274 usage_prot_P28274 prot_pool --> prot_P28274 0.0 usage_prot_P28321 usage_prot_P28321 prot_pool --> prot_P28321 0.0 usage_prot_P28496 usage_prot_P28496 prot_pool --> prot_P28496 0.0 -usage_prot_P28777 usage_prot_P28777 prot_pool --> prot_P28777 0.014581721673198017 +usage_prot_P28777 usage_prot_P28777 prot_pool --> prot_P28777 0.011161213349874036 usage_prot_P28789 usage_prot_P28789 prot_pool --> 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usage_prot_P30606 prot_pool --> prot_P30606 0.0 usage_prot_P30624 usage_prot_P30624 prot_pool --> prot_P30624 0.3294563936641971 usage_prot_P30777 usage_prot_P30777 prot_pool --> prot_P30777 0.0 -usage_prot_P30902 usage_prot_P30902 prot_pool --> prot_P30902 0.758901938282554 +usage_prot_P30902 usage_prot_P30902 prot_pool --> prot_P30902 0.04027647594300959 usage_prot_P30952 usage_prot_P30952 prot_pool --> prot_P30952 0.0 usage_prot_P31115 usage_prot_P31115 prot_pool --> prot_P31115 0.0 -usage_prot_P31116 usage_prot_P31116 prot_pool --> prot_P31116 0.016954994954948725 -usage_prot_P31373 usage_prot_P31373 prot_pool --> prot_P31373 0.02464674273574922 +usage_prot_P31116 usage_prot_P31116 prot_pool --> prot_P31116 0.01695499495494874 +usage_prot_P31373 usage_prot_P31373 prot_pool --> prot_P31373 0.024646742735750085 usage_prot_P31381 usage_prot_P31381 prot_pool --> prot_P31381 0.0 usage_prot_P31382 usage_prot_P31382 prot_pool --> prot_P31382 0.0 usage_prot_P31412 usage_prot_P31412 prot_pool --> prot_P31412 0.0 usage_prot_P31688 usage_prot_P31688 prot_pool --> prot_P31688 0.02443564224800174 usage_prot_P31755 usage_prot_P31755 prot_pool --> prot_P31755 0.0 usage_prot_P32048 usage_prot_P32048 prot_pool --> prot_P32048 0.0 -usage_prot_P32178 usage_prot_P32178 prot_pool --> prot_P32178 0.0008980439490849943 -usage_prot_P32179 usage_prot_P32179 prot_pool --> prot_P32179 0.022909630176072355 +usage_prot_P32178 usage_prot_P32178 prot_pool --> prot_P32178 0.0006633828635640007 +usage_prot_P32179 usage_prot_P32179 prot_pool --> prot_P32179 0.02290963017615152 usage_prot_P32190 usage_prot_P32190 prot_pool --> prot_P32190 0.0 usage_prot_P32191 usage_prot_P32191 prot_pool --> prot_P32191 0.0 usage_prot_P32263 usage_prot_P32263 prot_pool --> prot_P32263 3.7627575512284175e-05 usage_prot_P32264 usage_prot_P32264 prot_pool --> prot_P32264 0.006486823808271518 -usage_prot_P32288 usage_prot_P32288 prot_pool --> prot_P32288 0.0030614079635082 -usage_prot_P32316 usage_prot_P32316 prot_pool --> prot_P32316 2.8935358930067236 +usage_prot_P32288 usage_prot_P32288 prot_pool --> prot_P32288 0.0030614079635226748 +usage_prot_P32316 usage_prot_P32316 prot_pool --> prot_P32316 0.2414838869403105 usage_prot_P32318 usage_prot_P32318 prot_pool --> prot_P32318 2.4501998977318376e-08 usage_prot_P32327 usage_prot_P32327 prot_pool --> prot_P32327 0.0 -usage_prot_P32331 usage_prot_P32331 prot_pool --> prot_P32331 0.0001575471234656581 -usage_prot_P32332 usage_prot_P32332 prot_pool --> prot_P32332 0.020233903373627925 -usage_prot_P32340 usage_prot_P32340 prot_pool --> prot_P32340 0.14878792868549098 +usage_prot_P32331 usage_prot_P32331 prot_pool --> prot_P32331 0.00015754712346672614 +usage_prot_P32332 usage_prot_P32332 prot_pool --> prot_P32332 0.02023390337322016 +usage_prot_P32340 usage_prot_P32340 prot_pool --> prot_P32340 0.15020801871688644 usage_prot_P32347 usage_prot_P32347 prot_pool --> prot_P32347 0.0 usage_prot_P32352 usage_prot_P32352 prot_pool --> prot_P32352 0.0037023948469711914 usage_prot_P32353 usage_prot_P32353 prot_pool --> prot_P32353 0.008262677314925889 @@ -7251,24 +7251,24 @@ usage_prot_P32363 usage_prot_P32363 prot_pool --> prot_P32363 0.0 usage_prot_P32366 usage_prot_P32366 prot_pool --> prot_P32366 0.0 usage_prot_P32368 usage_prot_P32368 prot_pool --> prot_P32368 0.0 usage_prot_P32375 usage_prot_P32375 prot_pool --> prot_P32375 0.0 -usage_prot_P32377 usage_prot_P32377 prot_pool --> prot_P32377 0.05588958020224669 +usage_prot_P32377 usage_prot_P32377 prot_pool --> prot_P32377 0.05588958020649954 usage_prot_P32378 usage_prot_P32378 prot_pool --> prot_P32378 0.0 usage_prot_P32383 usage_prot_P32383 prot_pool --> prot_P32383 0.0 usage_prot_P32386 usage_prot_P32386 prot_pool --> prot_P32386 0.0 -usage_prot_P32419 usage_prot_P32419 prot_pool --> prot_P32419 1.2704172638740596e-06 -usage_prot_P32449 usage_prot_P32449 prot_pool --> prot_P32449 0.003955392932568877 +usage_prot_P32419 usage_prot_P32419 prot_pool --> prot_P32419 1.258756110077474e-06 +usage_prot_P32449 usage_prot_P32449 prot_pool --> prot_P32449 0.003027556374507523 usage_prot_P32451 usage_prot_P32451 prot_pool --> prot_P32451 0.0 -usage_prot_P32452 usage_prot_P32452 prot_pool --> prot_P32452 0.00021574476169689287 +usage_prot_P32452 usage_prot_P32452 prot_pool --> prot_P32452 0.00021574476169689295 usage_prot_P32459 usage_prot_P32459 prot_pool --> prot_P32459 0.0 -usage_prot_P32462 usage_prot_P32462 prot_pool --> prot_P32462 0.015622718902361178 +usage_prot_P32462 usage_prot_P32462 prot_pool --> prot_P32462 0.015622718903549968 usage_prot_P32463 usage_prot_P32463 prot_pool --> prot_P32463 0.0 usage_prot_P32465 usage_prot_P32465 prot_pool --> prot_P32465 0.0 usage_prot_P32466 usage_prot_P32466 prot_pool --> prot_P32466 2.833092592956789 usage_prot_P32467 usage_prot_P32467 prot_pool --> prot_P32467 0.0 usage_prot_P32469 usage_prot_P32469 prot_pool --> prot_P32469 0.0 -usage_prot_P32473 usage_prot_P32473 prot_pool --> prot_P32473 0.06420111546361058 -usage_prot_P32476 usage_prot_P32476 prot_pool --> prot_P32476 0.6002879186215094 -usage_prot_P32477 usage_prot_P32477 prot_pool --> prot_P32477 2.1331915821484914e-10 +usage_prot_P32473 usage_prot_P32473 prot_pool --> prot_P32473 0.5213025079651714 +usage_prot_P32476 usage_prot_P32476 prot_pool --> prot_P32476 0.6002879186671876 +usage_prot_P32477 usage_prot_P32477 prot_pool --> prot_P32477 2.1331915822225013e-10 usage_prot_P32486 usage_prot_P32486 prot_pool --> prot_P32486 0.0 usage_prot_P32487 usage_prot_P32487 prot_pool --> prot_P32487 0.0 usage_prot_P32528 usage_prot_P32528 prot_pool --> prot_P32528 0.0 @@ -7276,7 +7276,7 @@ usage_prot_P32563 usage_prot_P32563 prot_pool --> prot_P32563 0.0 usage_prot_P32567 usage_prot_P32567 prot_pool --> prot_P32567 0.0 usage_prot_P32573 usage_prot_P32573 prot_pool --> prot_P32573 0.0 usage_prot_P32579 usage_prot_P32579 prot_pool --> prot_P32579 0.0 -usage_prot_P32582 usage_prot_P32582 prot_pool --> prot_P32582 0.002732375312814017 +usage_prot_P32582 usage_prot_P32582 prot_pool --> prot_P32582 0.0027323753128141123 usage_prot_P32603 usage_prot_P32603 prot_pool --> prot_P32603 0.0 usage_prot_P32604 usage_prot_P32604 prot_pool --> prot_P32604 0.0 usage_prot_P32610 usage_prot_P32610 prot_pool --> prot_P32610 0.0 @@ -7288,35 +7288,35 @@ usage_prot_P32642 usage_prot_P32642 prot_pool --> prot_P32642 0.0 usage_prot_P32643 usage_prot_P32643 prot_pool --> prot_P32643 0.0 usage_prot_P32656 usage_prot_P32656 prot_pool --> prot_P32656 0.0 usage_prot_P32771 usage_prot_P32771 prot_pool --> prot_P32771 0.0 -usage_prot_P32784 usage_prot_P32784 prot_pool --> prot_P32784 0.7543571716338956 +usage_prot_P32784 usage_prot_P32784 prot_pool --> prot_P32784 0.754357171466341 usage_prot_P32785 usage_prot_P32785 prot_pool --> prot_P32785 0.0 usage_prot_P32791 usage_prot_P32791 prot_pool --> prot_P32791 0.0 -usage_prot_P32796 usage_prot_P32796 prot_pool --> prot_P32796 0.001202569173807015 +usage_prot_P32796 usage_prot_P32796 prot_pool --> prot_P32796 0.0011721432912749543 usage_prot_P32798 usage_prot_P32798 prot_pool --> prot_P32798 0.0 -usage_prot_P32799 usage_prot_P32799 prot_pool --> prot_P32799 0.007287524284364431 +usage_prot_P32799 usage_prot_P32799 prot_pool --> prot_P32799 0.025107751094053218 usage_prot_P32804 usage_prot_P32804 prot_pool --> prot_P32804 7.854377686321225e-05 usage_prot_P32837 usage_prot_P32837 prot_pool --> prot_P32837 0.0 usage_prot_P32842 usage_prot_P32842 prot_pool --> prot_P32842 0.0 usage_prot_P32861 usage_prot_P32861 prot_pool --> prot_P32861 0.0 usage_prot_P32874 usage_prot_P32874 prot_pool --> prot_P32874 0.0 -usage_prot_P32891 usage_prot_P32891 prot_pool --> prot_P32891 0.0 -usage_prot_P32895 usage_prot_P32895 prot_pool --> prot_P32895 0.0053901697845160496 +usage_prot_P32891 usage_prot_P32891 prot_pool --> prot_P32891 0.05674846219444069 +usage_prot_P32895 usage_prot_P32895 prot_pool --> prot_P32895 0.005390169784554727 usage_prot_P32901 usage_prot_P32901 prot_pool --> prot_P32901 0.0 usage_prot_P32903 usage_prot_P32903 prot_pool --> prot_P32903 0.0 usage_prot_P32906 usage_prot_P32906 prot_pool --> prot_P32906 0.0 usage_prot_P33300 usage_prot_P33300 prot_pool --> prot_P33300 0.0 -usage_prot_P33303 usage_prot_P33303 prot_pool --> prot_P33303 0.006302647797518763 +usage_prot_P33303 usage_prot_P33303 prot_pool --> prot_P33303 0.006302647797518764 usage_prot_P33312 usage_prot_P33312 prot_pool --> prot_P33312 5.311659714204637e-05 usage_prot_P33315 usage_prot_P33315 prot_pool --> prot_P33315 0.0 usage_prot_P33317 usage_prot_P33317 prot_pool --> prot_P33317 0.0 usage_prot_P33327 usage_prot_P33327 prot_pool --> prot_P33327 0.0 -usage_prot_P33330 usage_prot_P33330 prot_pool --> prot_P33330 1.652937529079184 +usage_prot_P33330 usage_prot_P33330 prot_pool --> prot_P33330 1.652937529076325 usage_prot_P33333 usage_prot_P33333 prot_pool --> prot_P33333 0.0 usage_prot_P33336 usage_prot_P33336 prot_pool --> prot_P33336 0.009489104297353921 usage_prot_P33401 usage_prot_P33401 prot_pool --> prot_P33401 0.0 usage_prot_P33412 usage_prot_P33412 prot_pool --> prot_P33412 0.0 usage_prot_P33413 usage_prot_P33413 prot_pool --> prot_P33413 0.0 -usage_prot_P33421 usage_prot_P33421 prot_pool --> prot_P33421 0.033660416708969784 +usage_prot_P33421 usage_prot_P33421 prot_pool --> prot_P33421 0.03374098672987619 usage_prot_P33550 usage_prot_P33550 prot_pool --> prot_P33550 0.0 usage_prot_P33734 usage_prot_P33734 prot_pool --> prot_P33734 0.020544584974038976 usage_prot_P33751 usage_prot_P33751 prot_pool --> prot_P33751 0.0 @@ -7324,7 +7324,7 @@ usage_prot_P33775 usage_prot_P33775 prot_pool --> prot_P33775 0.0 usage_prot_P33893 usage_prot_P33893 prot_pool --> prot_P33893 0.0 usage_prot_P34163 usage_prot_P34163 prot_pool --> prot_P34163 0.0 usage_prot_P34227 usage_prot_P34227 prot_pool --> prot_P34227 0.0 -usage_prot_P34230 usage_prot_P34230 prot_pool --> prot_P34230 0.35787502292489654 +usage_prot_P34230 usage_prot_P34230 prot_pool --> prot_P34230 0.3564520597379031 usage_prot_P34756 usage_prot_P34756 prot_pool --> prot_P34756 0.0 usage_prot_P35172 usage_prot_P35172 prot_pool --> prot_P35172 0.0 usage_prot_P35196 usage_prot_P35196 prot_pool --> prot_P35196 0.0 @@ -7335,23 +7335,23 @@ usage_prot_P35731 usage_prot_P35731 prot_pool --> prot_P35731 0.0 usage_prot_P35842 usage_prot_P35842 prot_pool --> prot_P35842 0.0 usage_prot_P36001 usage_prot_P36001 prot_pool --> prot_P36001 0.0 usage_prot_P36007 usage_prot_P36007 prot_pool --> prot_P36007 0.0 -usage_prot_P36010 usage_prot_P36010 prot_pool --> prot_P36010 0.004698804946988041 -usage_prot_P36013 usage_prot_P36013 prot_pool --> prot_P36013 0.0054592677668047615 +usage_prot_P36010 usage_prot_P36010 prot_pool --> prot_P36010 0.004698804948442481 +usage_prot_P36013 usage_prot_P36013 prot_pool --> prot_P36013 0.005459267766904521 usage_prot_P36014 usage_prot_P36014 prot_pool --> prot_P36014 0.0 -usage_prot_P36024 usage_prot_P36024 prot_pool --> prot_P36024 0.00011370517607151693 +usage_prot_P36024 usage_prot_P36024 prot_pool --> prot_P36024 0.00011370517607228775 usage_prot_P36029 usage_prot_P36029 prot_pool --> prot_P36029 0.0 usage_prot_P36033 usage_prot_P36033 prot_pool --> prot_P36033 0.0 usage_prot_P36035 usage_prot_P36035 prot_pool --> prot_P36035 0.0 usage_prot_P36051 usage_prot_P36051 prot_pool --> prot_P36051 0.0 usage_prot_P36060 usage_prot_P36060 prot_pool --> prot_P36060 0.0 usage_prot_P36062 usage_prot_P36062 prot_pool --> prot_P36062 0.0 -usage_prot_P36076 usage_prot_P36076 prot_pool --> prot_P36076 0.00011872816473884601 +usage_prot_P36076 usage_prot_P36076 prot_pool --> prot_P36076 0.00011872816473965088 usage_prot_P36088 usage_prot_P36088 prot_pool --> prot_P36088 0.0 usage_prot_P36107 usage_prot_P36107 prot_pool --> prot_P36107 0.0 -usage_prot_P36126 usage_prot_P36126 prot_pool --> prot_P36126 4.9094638795043345e-05 +usage_prot_P36126 usage_prot_P36126 prot_pool --> prot_P36126 4.9094640119231494e-05 usage_prot_P36136 usage_prot_P36136 prot_pool --> prot_P36136 0.0 usage_prot_P36143 usage_prot_P36143 prot_pool --> prot_P36143 0.0 -usage_prot_P36148 usage_prot_P36148 prot_pool --> prot_P36148 0.027107482089064605 +usage_prot_P36148 usage_prot_P36148 prot_pool --> prot_P36148 0.027107482089067686 usage_prot_P36150 usage_prot_P36150 prot_pool --> prot_P36150 0.0 usage_prot_P36156 usage_prot_P36156 prot_pool --> prot_P36156 0.0 usage_prot_P36165 usage_prot_P36165 prot_pool --> prot_P36165 0.0 @@ -7359,37 +7359,37 @@ usage_prot_P36421 usage_prot_P36421 prot_pool --> prot_P36421 0.0327028356769412 usage_prot_P36973 usage_prot_P36973 prot_pool --> prot_P36973 0.0 usage_prot_P37012 usage_prot_P37012 prot_pool --> prot_P37012 0.012168118618867935 usage_prot_P37020 usage_prot_P37020 prot_pool --> prot_P37020 0.0 -usage_prot_P37254 usage_prot_P37254 prot_pool --> prot_P37254 0.009172695793144503 -usage_prot_P37291 usage_prot_P37291 prot_pool --> prot_P37291 0.008192520750884929 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usage_prot_P38063 usage_prot_P38063 prot_pool --> prot_P38063 0.0 usage_prot_P38066 usage_prot_P38066 prot_pool --> prot_P38066 2.464763303253681e-06 usage_prot_P38067 usage_prot_P38067 prot_pool --> prot_P38067 0.0 usage_prot_P38071 usage_prot_P38071 prot_pool --> prot_P38071 0.0 usage_prot_P38074 usage_prot_P38074 prot_pool --> prot_P38074 0.0 usage_prot_P38075 usage_prot_P38075 prot_pool --> prot_P38075 0.03947178624475082 -usage_prot_P38077 usage_prot_P38077 prot_pool --> prot_P38077 1.3159535831370024 +usage_prot_P38077 usage_prot_P38077 prot_pool --> prot_P38077 0.06984034452894106 usage_prot_P38084 usage_prot_P38084 prot_pool --> prot_P38084 0.0 usage_prot_P38085 usage_prot_P38085 prot_pool --> prot_P38085 0.0 usage_prot_P38088 usage_prot_P38088 prot_pool --> prot_P38088 0.0 usage_prot_P38090 usage_prot_P38090 prot_pool --> prot_P38090 0.0 usage_prot_P38113 usage_prot_P38113 prot_pool --> prot_P38113 0.0 usage_prot_P38115 usage_prot_P38115 prot_pool --> prot_P38115 0.0 -usage_prot_P38122 usage_prot_P38122 prot_pool --> prot_P38122 0.00023230985563539583 +usage_prot_P38122 usage_prot_P38122 prot_pool --> prot_P38122 0.0002323098556369707 usage_prot_P38125 usage_prot_P38125 prot_pool --> prot_P38125 0.0 usage_prot_P38127 usage_prot_P38127 prot_pool --> prot_P38127 0.0011068950948585309 usage_prot_P38130 usage_prot_P38130 prot_pool --> prot_P38130 0.0 usage_prot_P38131 usage_prot_P38131 prot_pool --> prot_P38131 0.0 usage_prot_P38137 usage_prot_P38137 prot_pool --> prot_P38137 0.0 usage_prot_P38138 usage_prot_P38138 prot_pool --> prot_P38138 0.0 -usage_prot_P38139 usage_prot_P38139 prot_pool --> prot_P38139 0.0005349353338869734 +usage_prot_P38139 usage_prot_P38139 prot_pool --> prot_P38139 0.0005349369075239599 usage_prot_P38142 usage_prot_P38142 prot_pool --> prot_P38142 0.0 usage_prot_P38143 usage_prot_P38143 prot_pool --> prot_P38143 0.0 usage_prot_P38145 usage_prot_P38145 prot_pool --> prot_P38145 0.005450686484172471 @@ -7397,19 +7397,19 @@ usage_prot_P38149 usage_prot_P38149 prot_pool --> prot_P38149 0.0 usage_prot_P38152 usage_prot_P38152 prot_pool --> prot_P38152 0.012772141853097618 usage_prot_P38156 usage_prot_P38156 prot_pool --> prot_P38156 0.0 usage_prot_P38158 usage_prot_P38158 prot_pool --> prot_P38158 0.0 -usage_prot_P38169 usage_prot_P38169 prot_pool --> prot_P38169 0.004354734929335909 +usage_prot_P38169 usage_prot_P38169 prot_pool --> prot_P38169 0.004354734929326136 usage_prot_P38174 usage_prot_P38174 prot_pool --> prot_P38174 0.0 usage_prot_P38196 usage_prot_P38196 prot_pool --> prot_P38196 0.0 usage_prot_P38211 usage_prot_P38211 prot_pool --> prot_P38211 0.0 usage_prot_P38218 usage_prot_P38218 prot_pool --> prot_P38218 0.0 -usage_prot_P38221 usage_prot_P38221 prot_pool --> prot_P38221 0.00987439930352467 -usage_prot_P38225 usage_prot_P38225 prot_pool --> prot_P38225 0.0015378749687003253 +usage_prot_P38221 usage_prot_P38221 prot_pool --> prot_P38221 0.00987439930348173 +usage_prot_P38225 usage_prot_P38225 prot_pool --> prot_P38225 0.0015597235540969184 usage_prot_P38226 usage_prot_P38226 prot_pool --> prot_P38226 0.0 usage_prot_P38230 usage_prot_P38230 prot_pool --> prot_P38230 0.0 usage_prot_P38242 usage_prot_P38242 prot_pool --> prot_P38242 0.0 usage_prot_P38270 usage_prot_P38270 prot_pool --> prot_P38270 0.0 usage_prot_P38279 usage_prot_P38279 prot_pool --> prot_P38279 0.0 -usage_prot_P38286 usage_prot_P38286 prot_pool --> prot_P38286 0.020186394633638728 +usage_prot_P38286 usage_prot_P38286 prot_pool --> prot_P38286 0.020186394683424695 usage_prot_P38287 usage_prot_P38287 prot_pool --> prot_P38287 0.0 usage_prot_P38295 usage_prot_P38295 prot_pool --> prot_P38295 0.0 usage_prot_P38298 usage_prot_P38298 prot_pool --> prot_P38298 0.0 @@ -7417,16 +7417,16 @@ usage_prot_P38329 usage_prot_P38329 prot_pool --> prot_P38329 0.0 usage_prot_P38331 usage_prot_P38331 prot_pool --> prot_P38331 0.0 usage_prot_P38342 usage_prot_P38342 prot_pool --> prot_P38342 0.0 usage_prot_P38358 usage_prot_P38358 prot_pool --> prot_P38358 0.0 -usage_prot_P38359 usage_prot_P38359 prot_pool --> prot_P38359 0.03374014317423445 +usage_prot_P38359 usage_prot_P38359 prot_pool --> prot_P38359 0.03374014317423481 usage_prot_P38360 usage_prot_P38360 prot_pool --> prot_P38360 0.0 -usage_prot_P38361 usage_prot_P38361 prot_pool --> prot_P38361 0.04422595284325481 +usage_prot_P38361 usage_prot_P38361 prot_pool --> prot_P38361 0.04422595284359852 usage_prot_P38426 usage_prot_P38426 prot_pool --> prot_P38426 0.028198896311191803 usage_prot_P38427 usage_prot_P38427 prot_pool --> prot_P38427 0.0 -usage_prot_P38604 usage_prot_P38604 prot_pool --> prot_P38604 0.09105203330099063 -usage_prot_P38620 usage_prot_P38620 prot_pool --> prot_P38620 0.003983022351238133 -usage_prot_P38625 usage_prot_P38625 prot_pool --> prot_P38625 4.7056806217261684e-05 +usage_prot_P38604 usage_prot_P38604 prot_pool --> prot_P38604 0.09105203330791911 +usage_prot_P38620 usage_prot_P38620 prot_pool --> prot_P38620 0.003983022351266714 +usage_prot_P38625 usage_prot_P38625 prot_pool --> prot_P38625 4.7056806217262226e-05 usage_prot_P38626 usage_prot_P38626 prot_pool --> prot_P38626 8.886606334183781e-05 -usage_prot_P38627 usage_prot_P38627 prot_pool --> prot_P38627 0.002431028793129955 +usage_prot_P38627 usage_prot_P38627 prot_pool --> prot_P38627 0.0024310287931299563 usage_prot_P38628 usage_prot_P38628 prot_pool --> prot_P38628 0.0010068169057630475 usage_prot_P38631 usage_prot_P38631 prot_pool --> prot_P38631 0.0 usage_prot_P38635 usage_prot_P38635 prot_pool --> prot_P38635 4.185079666463251e-05 @@ -7434,8 +7434,8 @@ usage_prot_P38689 usage_prot_P38689 prot_pool --> prot_P38689 0.0 usage_prot_P38693 usage_prot_P38693 prot_pool --> prot_P38693 0.0 usage_prot_P38695 usage_prot_P38695 prot_pool --> prot_P38695 0.0 usage_prot_P38697 usage_prot_P38697 prot_pool --> prot_P38697 0.0 -usage_prot_P38698 usage_prot_P38698 prot_pool --> prot_P38698 0.08659455077771722 -usage_prot_P38702 usage_prot_P38702 prot_pool --> prot_P38702 0.005769808521354578 +usage_prot_P38698 usage_prot_P38698 prot_pool --> prot_P38698 0.1007670271897525 +usage_prot_P38702 usage_prot_P38702 prot_pool --> prot_P38702 0.0057698085216476465 usage_prot_P38703 usage_prot_P38703 prot_pool --> prot_P38703 0.0 usage_prot_P38705 usage_prot_P38705 prot_pool --> prot_P38705 0.002560156491140939 usage_prot_P38707 usage_prot_P38707 prot_pool --> prot_P38707 0.0327575744136394 @@ -7443,24 +7443,24 @@ usage_prot_P38708 usage_prot_P38708 prot_pool --> prot_P38708 0.0690259894225793 usage_prot_P38709 usage_prot_P38709 prot_pool --> prot_P38709 0.024630850456621008 usage_prot_P38710 usage_prot_P38710 prot_pool --> prot_P38710 0.0 usage_prot_P38714 usage_prot_P38714 prot_pool --> prot_P38714 0.0 -usage_prot_P38715 usage_prot_P38715 prot_pool --> prot_P38715 0.12530338055354862 -usage_prot_P38720 usage_prot_P38720 prot_pool --> prot_P38720 2.594346359558371e-13 +usage_prot_P38715 usage_prot_P38715 prot_pool --> prot_P38715 0.12530337990831597 +usage_prot_P38720 usage_prot_P38720 prot_pool --> prot_P38720 0.0 usage_prot_P38734 usage_prot_P38734 prot_pool --> prot_P38734 0.0 usage_prot_P38744 usage_prot_P38744 prot_pool --> prot_P38744 0.0 usage_prot_P38773 usage_prot_P38773 prot_pool --> prot_P38773 0.0 usage_prot_P38774 usage_prot_P38774 prot_pool --> prot_P38774 0.0 -usage_prot_P38787 usage_prot_P38787 prot_pool --> prot_P38787 9.03998917969169e-06 +usage_prot_P38787 usage_prot_P38787 prot_pool --> prot_P38787 9.039989179752973e-06 usage_prot_P38790 usage_prot_P38790 prot_pool --> prot_P38790 0.0 usage_prot_P38791 usage_prot_P38791 prot_pool --> prot_P38791 0.0 -usage_prot_P38795 usage_prot_P38795 prot_pool --> prot_P38795 0.0021261321228475865 +usage_prot_P38795 usage_prot_P38795 prot_pool --> prot_P38795 0.0021261321228428155 usage_prot_P38812 usage_prot_P38812 prot_pool --> prot_P38812 0.00024951417479531006 usage_prot_P38816 usage_prot_P38816 prot_pool --> prot_P38816 0.0 usage_prot_P38818 usage_prot_P38818 prot_pool --> prot_P38818 0.0 -usage_prot_P38824 usage_prot_P38824 prot_pool --> prot_P38824 0.05949567719695513 -usage_prot_P38840 usage_prot_P38840 prot_pool --> prot_P38840 0.002796876960277075 +usage_prot_P38824 usage_prot_P38824 prot_pool --> prot_P38824 0.0 +usage_prot_P38840 usage_prot_P38840 prot_pool --> prot_P38840 0.0027968769602770673 usage_prot_P38857 usage_prot_P38857 prot_pool --> prot_P38857 0.0 -usage_prot_P38858 usage_prot_P38858 prot_pool --> prot_P38858 5.550873069910679e-13 -usage_prot_P38891 usage_prot_P38891 prot_pool --> prot_P38891 0.0004011037030181486 +usage_prot_P38858 usage_prot_P38858 prot_pool --> prot_P38858 0.0 +usage_prot_P38891 usage_prot_P38891 prot_pool --> prot_P38891 0.0004011037030254376 usage_prot_P38913 usage_prot_P38913 prot_pool --> prot_P38913 0.00011094256898262331 usage_prot_P38921 usage_prot_P38921 prot_pool --> prot_P38921 0.0 usage_prot_P38925 usage_prot_P38925 prot_pool --> prot_P38925 0.00013994763724534115 @@ -7468,9 +7468,9 @@ usage_prot_P38929 usage_prot_P38929 prot_pool --> prot_P38929 0.0 usage_prot_P38954 usage_prot_P38954 prot_pool --> prot_P38954 0.0 usage_prot_P38967 usage_prot_P38967 prot_pool --> prot_P38967 0.0 usage_prot_P38971 usage_prot_P38971 prot_pool --> prot_P38971 0.0 -usage_prot_P38972 usage_prot_P38972 prot_pool --> prot_P38972 1.1527012652809148 +usage_prot_P38972 usage_prot_P38972 prot_pool --> prot_P38972 1.1527012653088693 usage_prot_P38986 usage_prot_P38986 prot_pool --> prot_P38986 0.0 -usage_prot_P38988 usage_prot_P38988 prot_pool --> prot_P38988 0.035979849329662125 +usage_prot_P38988 usage_prot_P38988 prot_pool --> prot_P38988 0.03597984932966215 usage_prot_P38992 usage_prot_P38992 prot_pool --> prot_P38992 0.0 usage_prot_P38993 usage_prot_P38993 prot_pool --> prot_P38993 0.0 usage_prot_P38994 usage_prot_P38994 prot_pool --> prot_P38994 0.0 @@ -7480,37 +7480,37 @@ usage_prot_P38999 usage_prot_P38999 prot_pool --> prot_P38999 0.0072577135644597 usage_prot_P39002 usage_prot_P39002 prot_pool --> prot_P39002 0.0 usage_prot_P39003 usage_prot_P39003 prot_pool --> prot_P39003 0.0 usage_prot_P39004 usage_prot_P39004 prot_pool --> prot_P39004 0.0 -usage_prot_P39006 usage_prot_P39006 prot_pool --> prot_P39006 0.00019207813979074708 +usage_prot_P39006 usage_prot_P39006 prot_pool --> prot_P39006 0.00019207813977807145 usage_prot_P39104 usage_prot_P39104 prot_pool --> prot_P39104 0.0 usage_prot_P39105 usage_prot_P39105 prot_pool --> prot_P39105 0.0 usage_prot_P39109 usage_prot_P39109 prot_pool --> prot_P39109 0.0 usage_prot_P39111 usage_prot_P39111 prot_pool --> prot_P39111 0.0 usage_prot_P39518 usage_prot_P39518 prot_pool --> prot_P39518 0.0 -usage_prot_P39522 usage_prot_P39522 prot_pool --> prot_P39522 0.053292456573851094 +usage_prot_P39522 usage_prot_P39522 prot_pool --> prot_P39522 0.05329245657385112 usage_prot_P39524 usage_prot_P39524 prot_pool --> prot_P39524 0.0 usage_prot_P39525 usage_prot_P39525 prot_pool --> prot_P39525 0.0 usage_prot_P39533 usage_prot_P39533 prot_pool --> prot_P39533 0.22942923376736873 usage_prot_P39535 usage_prot_P39535 prot_pool --> prot_P39535 0.0 -usage_prot_P39540 usage_prot_P39540 prot_pool --> prot_P39540 0.0004158753869400413 +usage_prot_P39540 usage_prot_P39540 prot_pool --> prot_P39540 0.00041587538946307915 usage_prot_P39676 usage_prot_P39676 prot_pool --> prot_P39676 0.0 usage_prot_P39683 usage_prot_P39683 prot_pool --> prot_P39683 7.5112222489234e-06 -usage_prot_P39692 usage_prot_P39692 prot_pool --> prot_P39692 0.004925283163526737 +usage_prot_P39692 usage_prot_P39692 prot_pool --> prot_P39692 0.0049252831635594845 usage_prot_P39708 usage_prot_P39708 prot_pool --> prot_P39708 0.0 usage_prot_P39713 usage_prot_P39713 prot_pool --> prot_P39713 0.0 usage_prot_P39714 usage_prot_P39714 prot_pool --> prot_P39714 0.0 -usage_prot_P39726 usage_prot_P39726 prot_pool --> prot_P39726 0.02060374901688273 +usage_prot_P39726 usage_prot_P39726 prot_pool --> prot_P39726 0.008247779772579676 usage_prot_P39730 usage_prot_P39730 prot_pool --> prot_P39730 0.0 usage_prot_P39924 usage_prot_P39924 prot_pool --> prot_P39924 0.0 usage_prot_P39932 usage_prot_P39932 prot_pool --> prot_P39932 0.0 usage_prot_P39953 usage_prot_P39953 prot_pool --> prot_P39953 0.0 -usage_prot_P39954 usage_prot_P39954 prot_pool --> prot_P39954 0.0003347651122765121 +usage_prot_P39954 usage_prot_P39954 prot_pool --> prot_P39954 0.00033476511225739554 usage_prot_P39965 usage_prot_P39965 prot_pool --> prot_P39965 0.0 -usage_prot_P39976 usage_prot_P39976 prot_pool --> prot_P39976 0.0 +usage_prot_P39976 usage_prot_P39976 prot_pool --> prot_P39976 0.053477306721071156 usage_prot_P39979 usage_prot_P39979 prot_pool --> prot_P39979 0.0 usage_prot_P39986 usage_prot_P39986 prot_pool --> prot_P39986 0.0 usage_prot_P39988 usage_prot_P39988 prot_pool --> prot_P39988 0.0 usage_prot_P40004 usage_prot_P40004 prot_pool --> prot_P40004 0.0 -usage_prot_P40009 usage_prot_P40009 prot_pool --> prot_P40009 0.025884569976197546 +usage_prot_P40009 usage_prot_P40009 prot_pool --> prot_P40009 0.024518186381198584 usage_prot_P40011 usage_prot_P40011 prot_pool --> prot_P40011 0.0 usage_prot_P40012 usage_prot_P40012 prot_pool --> prot_P40012 0.0 usage_prot_P40015 usage_prot_P40015 prot_pool --> prot_P40015 0.0 @@ -7519,17 +7519,17 @@ usage_prot_P40025 usage_prot_P40025 prot_pool --> prot_P40025 0.0 usage_prot_P40029 usage_prot_P40029 prot_pool --> prot_P40029 0.0 usage_prot_P40035 usage_prot_P40035 prot_pool --> prot_P40035 0.0239447428474692 usage_prot_P40039 usage_prot_P40039 prot_pool --> prot_P40039 0.0 -usage_prot_P40047 usage_prot_P40047 prot_pool --> prot_P40047 0.10030125559999999 +usage_prot_P40047 usage_prot_P40047 prot_pool --> prot_P40047 0.0 usage_prot_P40054 usage_prot_P40054 prot_pool --> prot_P40054 0.0 usage_prot_P40074 usage_prot_P40074 prot_pool --> prot_P40074 0.0 usage_prot_P40086 usage_prot_P40086 prot_pool --> prot_P40086 0.0 -usage_prot_P40099 usage_prot_P40099 prot_pool --> prot_P40099 1.9034766551584759 +usage_prot_P40099 usage_prot_P40099 prot_pool --> prot_P40099 0.0 usage_prot_P40106 usage_prot_P40106 prot_pool --> prot_P40106 0.044326094076730396 usage_prot_P40107 usage_prot_P40107 prot_pool --> prot_P40107 0.0 -usage_prot_P40215 usage_prot_P40215 prot_pool --> prot_P40215 0.11781044013155256 +usage_prot_P40215 usage_prot_P40215 prot_pool --> prot_P40215 0.11595345962442274 usage_prot_P40260 usage_prot_P40260 prot_pool --> prot_P40260 0.0 usage_prot_P40308 usage_prot_P40308 prot_pool --> prot_P40308 0.0 -usage_prot_P40319 usage_prot_P40319 prot_pool --> prot_P40319 0.0007318074862821392 +usage_prot_P40319 usage_prot_P40319 prot_pool --> prot_P40319 0.0007318074860688363 usage_prot_P40345 usage_prot_P40345 prot_pool --> prot_P40345 0.0 usage_prot_P40350 usage_prot_P40350 prot_pool --> prot_P40350 0.0 usage_prot_P40351 usage_prot_P40351 prot_pool --> prot_P40351 0.0 @@ -7539,12 +7539,12 @@ usage_prot_P40363 usage_prot_P40363 prot_pool --> prot_P40363 0.0 usage_prot_P40416 usage_prot_P40416 prot_pool --> prot_P40416 0.0 usage_prot_P40433 usage_prot_P40433 prot_pool --> prot_P40433 0.0 usage_prot_P40445 usage_prot_P40445 prot_pool --> prot_P40445 0.0 -usage_prot_P40459 usage_prot_P40459 prot_pool --> prot_P40459 1.4489899456017177e-06 +usage_prot_P40459 usage_prot_P40459 prot_pool --> prot_P40459 1.4489899456115405e-06 usage_prot_P40464 usage_prot_P40464 prot_pool --> prot_P40464 0.0 usage_prot_P40471 usage_prot_P40471 prot_pool --> prot_P40471 0.0 usage_prot_P40495 usage_prot_P40495 prot_pool --> prot_P40495 0.0215665264337018 -usage_prot_P40506 usage_prot_P40506 prot_pool --> prot_P40506 7.619473425183583e-05 -usage_prot_P40510 usage_prot_P40510 prot_pool --> prot_P40510 0.0016173256253882203 +usage_prot_P40506 usage_prot_P40506 prot_pool --> prot_P40506 7.619473425235236e-05 +usage_prot_P40510 usage_prot_P40510 prot_pool --> prot_P40510 0.0016173256253856473 usage_prot_P40527 usage_prot_P40527 prot_pool --> prot_P40527 0.0 usage_prot_P40544 usage_prot_P40544 prot_pool --> prot_P40544 0.0 usage_prot_P40545 usage_prot_P40545 prot_pool --> prot_P40545 0.0021440906329501146 @@ -7555,7 +7555,7 @@ usage_prot_P40559 usage_prot_P40559 prot_pool --> prot_P40559 0.0 usage_prot_P40580 usage_prot_P40580 prot_pool --> prot_P40580 0.0 usage_prot_P40581 usage_prot_P40581 prot_pool --> prot_P40581 0.0 usage_prot_P40825 usage_prot_P40825 prot_pool --> prot_P40825 0.008859154130962155 -usage_prot_P40857 usage_prot_P40857 prot_pool --> prot_P40857 0.0023884151891465162 +usage_prot_P40857 usage_prot_P40857 prot_pool --> prot_P40857 0.0023884151950370994 usage_prot_P40884 usage_prot_P40884 prot_pool --> prot_P40884 0.0 usage_prot_P40885 usage_prot_P40885 prot_pool --> prot_P40885 0.0 usage_prot_P40886 usage_prot_P40886 prot_pool --> prot_P40886 0.0 @@ -7565,18 +7565,18 @@ usage_prot_P40975 usage_prot_P40975 prot_pool --> prot_P40975 0.0 usage_prot_P40988 usage_prot_P40988 prot_pool --> prot_P40988 2.4101980169772022e-05 usage_prot_P40989 usage_prot_P40989 prot_pool --> prot_P40989 0.0 usage_prot_P41277 usage_prot_P41277 prot_pool --> prot_P41277 0.0 -usage_prot_P41338 usage_prot_P41338 prot_pool --> prot_P41338 0.1136233091753932 +usage_prot_P41338 usage_prot_P41338 prot_pool --> prot_P41338 0.07401176011712275 usage_prot_P41734 usage_prot_P41734 prot_pool --> prot_P41734 0.0 usage_prot_P41735 usage_prot_P41735 prot_pool --> prot_P41735 0.0 usage_prot_P41807 usage_prot_P41807 prot_pool --> prot_P41807 0.0 usage_prot_P41815 usage_prot_P41815 prot_pool --> prot_P41815 0.0 usage_prot_P41835 usage_prot_P41835 prot_pool --> prot_P41835 1.214189334385453e-06 -usage_prot_P41903 usage_prot_P41903 prot_pool --> prot_P41903 0.0008233251804857901 -usage_prot_P41909 usage_prot_P41909 prot_pool --> prot_P41909 0.36855681453022654 +usage_prot_P41903 usage_prot_P41903 prot_pool --> prot_P41903 0.0008276360477364101 +usage_prot_P41909 usage_prot_P41909 prot_pool --> prot_P41909 0.3670913789848625 usage_prot_P41911 usage_prot_P41911 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usage_prot_P47180 prot_pool --> prot_P47180 0.0 usage_prot_P47182 usage_prot_P47182 prot_pool --> prot_P47182 0.0 @@ -7636,7 +7636,7 @@ usage_prot_P47185 usage_prot_P47185 prot_pool --> prot_P47185 0.0 usage_prot_P47190 usage_prot_P47190 prot_pool --> prot_P47190 0.0 usage_prot_P47771 usage_prot_P47771 prot_pool --> prot_P47771 0.0 usage_prot_P47912 usage_prot_P47912 prot_pool --> prot_P47912 0.189018216655067 -usage_prot_P48015 usage_prot_P48015 prot_pool --> prot_P48015 0.04875369100365871 +usage_prot_P48015 usage_prot_P48015 prot_pool --> prot_P48015 0.019516336865154343 usage_prot_P48016 usage_prot_P48016 prot_pool --> prot_P48016 0.0 usage_prot_P48239 usage_prot_P48239 prot_pool --> prot_P48239 0.0 usage_prot_P48360 usage_prot_P48360 prot_pool --> prot_P48360 0.0 @@ -7646,21 +7646,21 @@ usage_prot_P48526 usage_prot_P48526 prot_pool --> prot_P48526 0.0 usage_prot_P48527 usage_prot_P48527 prot_pool --> prot_P48527 0.0 usage_prot_P48567 usage_prot_P48567 prot_pool --> prot_P48567 0.0 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usage_prot_Q06144 usage_prot_Q06144 prot_pool --> prot_Q06144 0.0 usage_prot_Q06147 usage_prot_Q06147 prot_pool --> prot_Q06147 0.0 usage_prot_Q06178 usage_prot_Q06178 prot_pool --> prot_Q06178 0.0 usage_prot_Q06204 usage_prot_Q06204 prot_pool --> prot_Q06204 0.0 -usage_prot_Q06236 usage_prot_Q06236 prot_pool --> prot_Q06236 0.02841947091360907 +usage_prot_Q06236 usage_prot_Q06236 prot_pool --> prot_Q06236 0.028487496136988085 usage_prot_Q06321 usage_prot_Q06321 prot_pool --> prot_Q06321 0.0 usage_prot_Q06328 usage_prot_Q06328 prot_pool --> prot_Q06328 0.0 usage_prot_Q06346 usage_prot_Q06346 prot_pool --> prot_Q06346 0.0 usage_prot_Q06350 usage_prot_Q06350 prot_pool --> prot_Q06350 0.0 usage_prot_Q06389 usage_prot_Q06389 prot_pool --> prot_Q06389 0.0 -usage_prot_Q06405 usage_prot_Q06405 prot_pool --> prot_Q06405 0.4333517781853737 +usage_prot_Q06405 usage_prot_Q06405 prot_pool --> prot_Q06405 0.022998864001379328 usage_prot_Q06408 usage_prot_Q06408 prot_pool --> prot_Q06408 0.0 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prot_Q08485 0.0 -usage_prot_Q08548 usage_prot_Q08548 prot_pool --> prot_Q08548 0.6287172418842614 +usage_prot_Q08548 usage_prot_Q08548 prot_pool --> prot_Q08548 0.6287172407427238 usage_prot_Q08558 usage_prot_Q08558 prot_pool --> prot_Q08558 0.0 usage_prot_Q08579 usage_prot_Q08579 prot_pool --> prot_Q08579 0.0 usage_prot_Q08645 usage_prot_Q08645 prot_pool --> prot_Q08645 0.0 -usage_prot_Q08650 usage_prot_Q08650 prot_pool --> prot_Q08650 0.019929875452400766 +usage_prot_Q08650 usage_prot_Q08650 prot_pool --> prot_Q08650 0.01992989864144613 usage_prot_Q08686 usage_prot_Q08686 prot_pool --> prot_Q08686 0.0 usage_prot_Q08689 usage_prot_Q08689 prot_pool --> prot_Q08689 0.0 usage_prot_Q08742 usage_prot_Q08742 prot_pool --> prot_Q08742 0.0 @@ -7939,7 +7939,7 @@ usage_prot_Q12010 usage_prot_Q12010 prot_pool --> prot_Q12010 0.0 usage_prot_Q12031 usage_prot_Q12031 prot_pool --> prot_Q12031 0.0 usage_prot_Q12036 usage_prot_Q12036 prot_pool --> prot_Q12036 0.022052303026939706 usage_prot_Q12040 usage_prot_Q12040 prot_pool --> prot_Q12040 0.0 -usage_prot_Q12043 usage_prot_Q12043 prot_pool --> prot_Q12043 0.0007968256017488778 +usage_prot_Q12043 usage_prot_Q12043 prot_pool --> prot_Q12043 0.0007968256017489683 usage_prot_Q12051 usage_prot_Q12051 prot_pool --> prot_Q12051 0.0 usage_prot_Q12055 usage_prot_Q12055 prot_pool --> prot_Q12055 0.0013628593424865666 usage_prot_Q12068 usage_prot_Q12068 prot_pool --> prot_Q12068 0.06926843031545774 @@ -7950,35 +7950,35 @@ usage_prot_Q12116 usage_prot_Q12116 prot_pool --> prot_Q12116 0.0 usage_prot_Q12119 usage_prot_Q12119 prot_pool --> prot_Q12119 0.0 usage_prot_Q12122 usage_prot_Q12122 prot_pool --> prot_Q12122 0.0 usage_prot_Q12154 usage_prot_Q12154 prot_pool --> prot_Q12154 0.0 -usage_prot_Q12165 usage_prot_Q12165 prot_pool --> prot_Q12165 0.6520197369797612 -usage_prot_Q12166 usage_prot_Q12166 prot_pool --> prot_Q12166 0.005611323272389369 +usage_prot_Q12165 usage_prot_Q12165 prot_pool --> prot_Q12165 0.034604019209996124 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usage_prot_Q12359 prot_pool --> prot_Q12359 0.5506056135207392 usage_prot_Q12362 usage_prot_Q12362 prot_pool --> prot_Q12362 0.018809202598948565 usage_prot_Q12372 usage_prot_Q12372 prot_pool --> prot_Q12372 0.0 usage_prot_Q12375 usage_prot_Q12375 prot_pool --> prot_Q12375 0.04266733959148965 usage_prot_Q12382 usage_prot_Q12382 prot_pool --> prot_Q12382 0.0 -usage_prot_Q12412 usage_prot_Q12412 prot_pool --> prot_Q12412 0.017710434883536397 +usage_prot_Q12412 usage_prot_Q12412 prot_pool --> prot_Q12412 0.01771043536122497 usage_prot_Q12428 usage_prot_Q12428 prot_pool --> prot_Q12428 0.0 usage_prot_Q12436 usage_prot_Q12436 prot_pool --> prot_Q12436 0.0 usage_prot_Q12447 usage_prot_Q12447 prot_pool --> prot_Q12447 0.0 @@ -7987,25 +7987,25 @@ usage_prot_Q12455 usage_prot_Q12455 prot_pool --> prot_Q12455 0.0003933298532798 usage_prot_Q12458 usage_prot_Q12458 prot_pool --> prot_Q12458 0.0 usage_prot_Q12471 usage_prot_Q12471 prot_pool --> prot_Q12471 0.0 usage_prot_Q12473 usage_prot_Q12473 prot_pool --> prot_Q12473 0.0 -usage_prot_Q12482 usage_prot_Q12482 prot_pool --> prot_Q12482 0.18387847225312745 +usage_prot_Q12482 usage_prot_Q12482 prot_pool --> prot_Q12482 0.18387847225434456 usage_prot_Q12494 usage_prot_Q12494 prot_pool --> prot_Q12494 0.0 usage_prot_Q12520 usage_prot_Q12520 prot_pool --> prot_Q12520 0.0 usage_prot_Q12524 usage_prot_Q12524 prot_pool --> prot_Q12524 0.0 usage_prot_Q12525 usage_prot_Q12525 prot_pool --> prot_Q12525 0.0 usage_prot_Q12674 usage_prot_Q12674 prot_pool --> prot_Q12674 0.0 usage_prot_Q12675 usage_prot_Q12675 prot_pool --> prot_Q12675 0.0 -usage_prot_Q12676 usage_prot_Q12676 prot_pool --> prot_Q12676 9.199454193987252e-06 +usage_prot_Q12676 usage_prot_Q12676 prot_pool --> prot_Q12676 9.1994541940678e-06 usage_prot_Q12680 usage_prot_Q12680 prot_pool --> prot_Q12680 0.0 usage_prot_Q12691 usage_prot_Q12691 prot_pool --> prot_Q12691 0.0 usage_prot_Q12746 usage_prot_Q12746 prot_pool --> prot_Q12746 0.0 -usage_prot_Q3E731 usage_prot_Q3E731 prot_pool --> prot_Q3E731 0.03815102755931324 +usage_prot_Q3E731 usage_prot_Q3E731 prot_pool --> prot_Q3E731 0.0 usage_prot_Q3E790 usage_prot_Q3E790 prot_pool --> prot_Q3E790 0.0 usage_prot_Q3E7B6 usage_prot_Q3E7B6 prot_pool --> prot_Q3E7B6 0.0 usage_prot_Q99190 usage_prot_Q99190 prot_pool --> prot_Q99190 0.08223331067052125 usage_prot_Q99258 usage_prot_Q99258 prot_pool --> prot_Q99258 0.0005698989734288502 usage_prot_Q99271 usage_prot_Q99271 prot_pool --> prot_Q99271 0.0 -usage_prot_Q99297 usage_prot_Q99297 prot_pool --> prot_Q99297 0.07250998295997993 +usage_prot_Q99297 usage_prot_Q99297 prot_pool --> prot_Q99297 0.07250998296002337 usage_prot_Q99312 usage_prot_Q99312 prot_pool --> prot_Q99312 0.0 usage_prot_Q99321 usage_prot_Q99321 prot_pool --> prot_Q99321 0.0 -prot_pool_exchange prot_pool_exchange --> prot_pool 79.41085838369261 -usage_prot_standard usage_prot_standard prot_pool --> prot_standard 0.14803505467596126 +prot_pool_exchange prot_pool_exchange --> prot_pool 49.69271941927763 +usage_prot_standard usage_prot_standard prot_pool --> prot_standard 0.15328147158856742 diff --git a/results/modelSimulation/allFluxes_CN4.tsv b/results/modelSimulation/allFluxes_CN4.tsv index 79ac096..431433b 100644 --- a/results/modelSimulation/allFluxes_CN4.tsv +++ b/results/modelSimulation/allFluxes_CN4.tsv @@ -16,9 +16,9 @@ r_0006_EXP_1 1,6-beta-glucan synthase 0.38423648758316814 prot_P33336 + UDP-D-gl r_0006_EXP_2 1,6-beta-glucan synthase 1.4417126800627231 prot_P32486 + UDP-D-glucose --> (1->6)-beta-D-glucan + H+ + UDP 0.0 r_0007 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase 0.25657118055555556 prot_P40545 + 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide --> 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide 0.008356708763266002 r_0012 1-pyrroline-5-carboxylate dehydrogenase 11.932407407407407 prot_P07275 + 1-pyrroline-5-carboxylate + 2.0 H2O + NAD --> H+ + L-glutamate + NADH 0.06753022171843157 -r_0013 2,3-diketo-5-methylthio-1-phosphopentane degradation reaction 0.013992777777777778 prot_P32626 + 0.011599444444444445 prot_Q03677 + 5-(methylsulfanyl)-2,3-dioxopentyl phosphate + H2O + oxygen --> 4-methylthio-2-oxobutanoate + formate + 2.0 H+ + phosphate 1.9000000614987463e-05 -r_0014 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase 188.09203142536475 prot_Q12362 + 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + H+ + H2O --> 5-amino-6-(5-phosphoribitylamino)uracil + ammonium 9.999999710999519e-05 -r_0015 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH) 0.5311659867712155 prot_P33312 + 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + H+ + NADPH --> 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + NADP(+) 9.999999710999519e-05 +r_0013 2,3-diketo-5-methylthio-1-phosphopentane degradation reaction 0.013992777777777778 prot_P32626 + 0.011599444444444445 prot_Q03677 + 5-(methylsulfanyl)-2,3-dioxopentyl phosphate + H2O + oxygen --> 4-methylthio-2-oxobutanoate + formate + 2.0 H+ + phosphate 1.9000000611411882e-05 +r_0014 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase 188.09203142536475 prot_Q12362 + 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + H+ + H2O --> 5-amino-6-(5-phosphoribitylamino)uracil + ammonium 9.999999710998968e-05 +r_0015 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH) 0.5311659867712155 prot_P33312 + 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + H+ + NADPH --> 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + NADP(+) 9.999999710998968e-05 r_0016_EXP_1 2-aceto-2-hydroxybutanoate synthase 0.08099546044098574 prot_P07342 + 0.03673476005188067 prot_P25605 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.0 r_0016_EXP_2 2-aceto-2-hydroxybutanoate synthase 0.04049773022049287 prot_P07342 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.0265490320174191 r_0017 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 63.477512816721614 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + ATP --> (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + AMP + H+ 0.0 @@ -28,9 +28,9 @@ r_0018_EXP_3 2-aminoadipate transaminase 0.009033549783549784 prot_P47039 + 2-ox r_0018_REV_EXP_1 2-aminoadipate transaminase (reversible) 0.7210471896303212 prot_P10356 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 r_0018_REV_EXP_2 2-aminoadipate transaminase (reversible) 0.8480978260869565 prot_P53090 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 r_0018_REV_EXP_3 2-aminoadipate transaminase (reversible) 1.8137766188613647 prot_P47039 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 -r_0019 2-dehydropantoate 2-reductase 0.4757888888888889 prot_P38787 + 2-dehydropantoate + H+ + NADPH --> (R)-pantoate + NADP(+) 1.9000000614987463e-05 +r_0019 2-dehydropantoate 2-reductase 0.4757888888888889 prot_P38787 + 2-dehydropantoate + H+ + NADPH --> (R)-pantoate + NADP(+) 1.9000000611411882e-05 r_0020_EXP_1 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09351092896174863 prot_P14843 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 -r_0020_EXP_2 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.03345248332545636 +r_0020_EXP_2 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.03345248332545642 r_0021 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase 0.2834173315594083 prot_O13525 + 0.266570923780901 prot_P27680 + 0.191209663200305 prot_P41735 + 0.2544937516539746 prot_P49017 + 0.39274288726487816 prot_P53318 + 0.21981040253855474 prot_Q05779 + 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine --> 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + S-adenosyl-L-homocysteine 0.0 r_0022 2-hexaprenyl-6-methoxyphenol monooxygenase 0.5305538973582232 prot_O13525 + 0.49901762096258073 prot_P27680 + 0.3579422312153493 prot_P41735 + 0.47640929737929355 prot_P49017 + 0.7352100464414428 prot_P53318 + 0.4114824774654426 prot_Q05779 + 2-hexaprenyl-6-methoxyphenol + oxygen --> 2-hexaprenyl-6-methoxy-1,4-benzoquinone + H2O 0.0 r_0023 2-isopropylmalate hydratase 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> 2-isopropylmalate 0.0 @@ -39,7 +39,7 @@ r_0024_EXP_1 2-isopropylmalate synthase 1.3779912980420594 prot_P06208 + 3-methy r_0024_EXP_2 2-isopropylmalate synthase 1.353637901861252 prot_Q12166 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.0 r_0025 2-isopropylmalate synthase 1.3779912980420594 prot_P06208 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.0362523293945085 r_0026_EXP_1 2-keto-4-methylthiobutyrate transamination 0.011265116279069768 prot_P38891 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 -r_0026_EXP_2 2-keto-4-methylthiobutyrate transamination 0.010755813953488373 prot_P47176 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 1.9000000614987463e-05 +r_0026_EXP_2 2-keto-4-methylthiobutyrate transamination 0.010755813953488373 prot_P47176 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 1.9000000611411882e-05 r_0026_EXP_3 2-keto-4-methylthiobutyrate transamination 1.219140625 prot_P53090 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 r_0026_EXP_4 2-keto-4-methylthiobutyrate transamination 1.5784250269687163 prot_P38840 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 r_0027 2-methylcitrate dehydratase 8.195345706873871 prot_P49367 + homocitrate --> but-1-ene-1,2,4-tricarboxylic acid + H2O 0.032939964005654 @@ -47,25 +47,25 @@ r_0027_REV 2-methylcitrate dehydratase (reversible) 8.350111111111111 prot_P4936 r_0028 2-methylcitrate synthase 0.10578556263269638 prot_P43635 + H2O + oxaloacetate + propionyl-CoA --> 2-methylcitrate + coenzyme A + H+ 0.0 r_0029 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.0362523293945085 r_0030 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.0 -r_0032 3',5'-bisphosphate nucleotidase 0.9886111111111111 prot_P32179 + adenosine 3',5'-bismonophosphate + H2O --> AMP + phosphate 0.01192491661357767 +r_0032 3',5'-bisphosphate nucleotidase 0.9886111111111111 prot_P32179 + adenosine 3',5'-bismonophosphate + H2O --> AMP + phosphate 0.011924916613574097 r_0033_EXP_1 3',5'-cyclic-nucleotide phosphodiesterase 0.5557671957671958 prot_P22434 + 3',5'-cyclic AMP + H2O --> AMP + H+ 0.0 r_0033_EXP_2 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic AMP + H2O --> AMP + H+ 0.0 r_0034 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic dAMP + H2O --> dAMP + H+ 0.0 r_0035 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic IMP + H2O --> H+ + IMP 0.0 r_0036 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic GMP + H2O --> GMP + H+ 0.0 r_0037 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic CMP + H2O --> CMP + H+ 0.0 -r_0038 3,4-dihydroxy-2-butanone-4-phosphate synthase 2.8494949494949493 prot_Q99258 + D-ribulose 5-phosphate --> 2-hydroxy-3-oxobutyl phosphate + formate + H+ 0.00019999999421999037 -r_0039 3-dehydroquinate dehydratase 0.1565905017921147 prot_P08566 + 3-dehydroquinate --> 3-dehydroshikimate + H2O 0.03345248332545636 -r_0040 3-dehydroquinate synthase 0.1565905017921147 prot_P08566 + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 3-dehydroquinate + phosphate 0.03345248332545636 +r_0038 3,4-dihydroxy-2-butanone-4-phosphate synthase 2.8494949494949493 prot_Q99258 + D-ribulose 5-phosphate --> 2-hydroxy-3-oxobutyl phosphate + formate + H+ 0.00019999999421997937 +r_0039 3-dehydroquinate dehydratase 0.1565905017921147 prot_P08566 + 3-dehydroquinate --> 3-dehydroshikimate + H2O 0.03345248332545642 +r_0040 3-dehydroquinate synthase 0.1565905017921147 prot_P08566 + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 3-dehydroquinate + phosphate 0.03345248332545642 r_0041 3-dehydrosphinganine reductase 9.338785046728972 prot_P38342 + 3-ketosphinganine + H+ + NADPH --> NADP(+) + sphinganine 0.0 r_0042_EXP_1 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 r_0042_EXP_2 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09351092896174863 prot_P14843 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 r_0043_EXP_1 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase 0.2467406921478821 prot_Q12184 + 3-hexaprenyl-4-hydroxybenzoic acid + 0.5 oxygen --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 r_0043_EXP_2 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase 0.30872310057092667 prot_P48360 + 3-hexaprenyl-4-hydroxybenzoic acid + 0.5 oxygen --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 r_0044 3-hexaprenyl-4-hydroxy-5-methoxybenzoate decarboxylase 1.6143115942028985 prot_P33751 + 3.391545893719807 prot_Q03034 + 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid + H+ --> 2-hexaprenyl-6-methoxyphenol + carbon dioxide 0.0 -r_0045 3-hydroxy-L-kynurenine hydrolase 4.0501587301587305 prot_Q05979 + 3-hydroxy-L-kynurenine + H2O --> 3-hydroxyanthranilate + H+ + L-alanine 0.0006069999973987722 +r_0045 3-hydroxy-L-kynurenine hydrolase 4.0501587301587305 prot_Q05979 + 3-hydroxy-L-kynurenine + H2O --> 3-hydroxyanthranilate + H+ + L-alanine 0.0006069999973988254 r_0057 3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxytetradecanoyl-CoA + NAD --> 3-oxotetradecanoyl-CoA + H+ + NADH 0.0 -r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.22483333333333333 prot_P47096 + 3-hydroxyanthranilate + oxygen --> 2-amino-3-carboxymuconate-6-semialdehyde 0.0006069999973987722 +r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.22483333333333333 prot_P47096 + 3-hydroxyanthranilate + oxygen --> 2-amino-3-carboxymuconate-6-semialdehyde 0.0006069999973988254 r_0059 3-isopropylmalate 3-methyltransferase 195.1806339044363 prot_P32643 + (2R,3S)-3-isopropylmalate + S-adenosyl-L-methionine --> 3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoate + S-adenosyl-L-homocysteine 0.0 r_0060 3-isopropylmalate dehydratase 0.6097968324816225 prot_P07264 + (2R,3S)-3-isopropylmalate --> 2-isopropylmaleic acid + H2O 0.0 r_0060_REV 3-isopropylmalate dehydratase (reversible) 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> (2R,3S)-3-isopropylmalate 0.0362523293945085 @@ -73,12 +73,12 @@ r_0061 3-isopropylmalate dehydrogenase 0.06638207225630538 prot_P04173 + (2R,3S) r_0062_EXP_1 3-methyl-2-oxobutanoate decarboxylase 0.27589605734767025 prot_P26263 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 r_0062_EXP_2 3-methyl-2-oxobutanoate decarboxylase 0.11780651340996169 prot_P06169 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 r_0062_EXP_3 3-methyl-2-oxobutanoate decarboxylase 0.27738351254480287 prot_P16467 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 -r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.226834113807293 prot_P38122 + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O --> 2-dehydropantoate + THF 1.9000000614987463e-05 +r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.226834113807293 prot_P38122 + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O --> 2-dehydropantoate + THF 1.9000000611411882e-05 r_0064_EXP_1 3-methyl-2-oxopentanoate decarboxylase 0.13096934865900384 prot_Q07471 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_2 3-methyl-2-oxopentanoate decarboxylase 0.27589605734767025 prot_P26263 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_3 3-methyl-2-oxopentanoate decarboxylase 0.11780651340996169 prot_P06169 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_4 3-methyl-2-oxopentanoate decarboxylase 0.27738351254480287 prot_P16467 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 -r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 1.4447337962962963 prot_P08566 + 3-phosphoshikimic acid + phosphoenolpyruvate --> 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid + phosphate 0.03345248332545636 +r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 1.4447337962962963 prot_P08566 + 3-phosphoshikimic acid + phosphoenolpyruvate --> 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid + phosphate 0.03345248332545642 r_0066 4-amino-4-deoxychorismate synthase 1446.797385620915 prot_P37254 + chorismate + L-glutamine --> 4-amino-4-deoxychorismate + L-glutamate 6.3400002545677125e-06 r_0067 4-aminobenzoate synthase 6.233918128654971 prot_Q03266 + 4-amino-4-deoxychorismate --> 4-aminobenzoate + H+ + pyruvate 6.3400002545677125e-06 r_0068 4-aminobutyrate transaminase 43.25653594771242 prot_P17649 + 2-oxoglutarate + gamma-aminobutyrate --> L-glutamate + succinic semialdehyde 0.0 @@ -88,22 +88,22 @@ r_0072 4-methyl-2-oxopentanoate decarboxylase 2.2341830065359476 prot_Q07471 + 4 r_0073_EXP_1 4PP-IP5 depyrophosphorylation to IP6 0.9485014619883041 prot_Q06685 + 4-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0073_EXP_2 4PP-IP5 depyrophosphorylation to IP6 2396.8888888888887 prot_Q99321 + 4-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0074 4PP-IP5 pyrophosphorylation to 4,5-PP2-IP4 1106.9444444444443 prot_Q12494 + 4-diphospho-1D-myo-inositol pentakisphosphate + ATP + H+ --> 4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate + ADP 0.0 -r_0075 5'-methylthioadenosine phosphorylase 40.44551282051282 prot_Q07938 + 5'-S-methyl-5'-thioadenosine + phosphate --> adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate 1.9000000614987463e-05 +r_0075 5'-methylthioadenosine phosphorylase 40.44551282051282 prot_Q07938 + 5'-S-methyl-5'-thioadenosine + phosphate --> adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate 1.9000000611411882e-05 r_0076_EXP_1 5'-nucleotidase (CMP) 0.029597457627118642 prot_P40025 + CMP + H2O --> cytidine + phosphate 0.0 r_0076_EXP_2 5'-nucleotidase (CMP) 51.769157967243395 prot_P53078 + CMP + H2O --> cytidine + phosphate 0.0 r_0077 5'-nucleotidase (IMP) 1.056172839506173 prot_Q99312 + H2O + IMP --> inosine + phosphate 0.0 r_0078_EXP_1 5'-nucleotidase (UMP) 0.029597457627118642 prot_P40025 + H2O + UMP --> phosphate + uridine 0.0 r_0078_EXP_2 5'-nucleotidase (UMP) 201.12835425109543 prot_P53078 + H2O + UMP --> phosphate + uridine 0.0 -r_0079 5'-phosphoribosylformyl glycinamidine synthetase 112.56379587281619 prot_P38972 + 5'-phosphoribosyl-N-formylglycineamide + ATP + H2O + L-glutamine --> 5'-phosphoribosyl-N-formylglycineamidine + ADP + H+ + L-glutamate + phosphate 0.010240426385265499 -r_0080_EXP_1 5,10-methylenetetrahydrofolate reductase (NADPH) 0.12837152777777777 prot_P46151 + 0.11902777777777777 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.02221437325755714 +r_0079 5'-phosphoribosylformyl glycinamidine synthetase 112.56379587281619 prot_P38972 + 5'-phosphoribosyl-N-formylglycineamide + ATP + H2O + L-glutamine --> 5'-phosphoribosyl-N-formylglycineamidine + ADP + H+ + L-glutamate + phosphate 0.01024042638525807 +r_0080_EXP_1 5,10-methylenetetrahydrofolate reductase (NADPH) 0.12837152777777777 prot_P46151 + 0.11902777777777777 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.022189731824949946 r_0080_EXP_2 5,10-methylenetetrahydrofolate reductase (NADPH) 0.3705144833549503 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.0 r_0081 5-aminolevulinate synthase 0.08588252314814815 prot_P09950 + H+ + L-glycine + succinyl-CoA --> 5-aminolevulinate + carbon dioxide + coenzyme A 0.0 r_0082 5-diphosphoinositol-1,2,3,4,6-pentakisphosphate diphosphohydrolase 2396.8888888888887 prot_Q99321 + 5-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0083 5-diphosphoinositol-1,2,3,4,6-pentakisphosphate synthase 1106.9444444444443 prot_Q12494 + ATP + myo-inositol hexakisphosphate --> 5-diphospho-1D-myo-inositol pentakisphosphate + ADP 0.0 r_0084 5-formethyltetrahydrofolate cyclo-ligase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP --> 5,10-methenyl-THF + ADP + phosphate 0.0 r_0085 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase 72.27272727272727 prot_P05694 + 5-methyltetrahydropteroyltri-L-glutamic acid + L-homocysteine --> L-methionine + tetrahydropteroyltri-L-glutamic acid 0.0 -r_0086 5-methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase 0.4617340067340067 prot_P47095 + S-methyl-5-thio-D-ribulose 1-phosphate --> 5-(methylsulfanyl)-2,3-dioxopentyl phosphate + H2O 1.9000000614987463e-05 -r_0087 5-methylthioribose-1-phosphate isomerase 0.961965811965812 prot_Q06489 + S-methyl-5-thio-alpha-D-ribose 1-phosphate --> S-methyl-5-thio-D-ribulose 1-phosphate 1.9000000614987463e-05 +r_0086 5-methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase 0.4617340067340067 prot_P47095 + S-methyl-5-thio-D-ribulose 1-phosphate --> 5-(methylsulfanyl)-2,3-dioxopentyl phosphate + H2O 1.9000000611411882e-05 +r_0087 5-methylthioribose-1-phosphate isomerase 0.961965811965812 prot_Q06489 + S-methyl-5-thio-alpha-D-ribose 1-phosphate --> S-methyl-5-thio-D-ribulose 1-phosphate 1.9000000611411882e-05 r_0087_REV 5-methylthioribose-1-phosphate isomerase (reversible) 0.961965811965812 prot_Q06489 + S-methyl-5-thio-D-ribulose 1-phosphate --> S-methyl-5-thio-alpha-D-ribose 1-phosphate 0.0 r_0088 5PP-IP5 pyrophosphorylation to 4,5-PP2-IP4 0.9485014619883041 prot_Q06685 + 5-diphospho-1D-myo-inositol pentakisphosphate + 2.0 H+ + phosphate --> 4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate + H2O 0.0 r_0088_REV 5PP-IP5 pyrophosphorylation to 4,5-PP2-IP4 (reversible) 0.9485014619883041 prot_Q06685 + 4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate + H2O --> 5-diphospho-1D-myo-inositol pentakisphosphate + 2.0 H+ + phosphate 0.0 @@ -112,7 +112,7 @@ r_0089_REV 5PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 (reversible) 0.94850146198 r_0090_EXP_1 6-phosphofructo-2-kinase 0.4896069182389937 prot_P40433 + ATP + D-fructose 6-phosphate --> ADP + beta-D-fructose 2,6-bisphosphate + H+ 0.0 r_0090_EXP_2 6-phosphofructo-2-kinase 0.23751572327044027 prot_Q12471 + ATP + D-fructose 6-phosphate --> ADP + beta-D-fructose 2,6-bisphosphate + H+ 0.0 r_0091_EXP_1 6-phosphogluconolactonase 0.8951362104267674 prot_P53315 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.06621328472896192 -r_0091_EXP_2 6-phosphogluconolactonase 0.87424298616765 prot_P38858 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.24754566296065791 +r_0091_EXP_2 6-phosphogluconolactonase 0.87424298616765 prot_P38858 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.24745697949260764 r_0092_EXP_1 6PP-IP5 depyrophosphorylation to IP6 0.9485014619883041 prot_Q06685 + 6-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0092_EXP_2 6PP-IP5 depyrophosphorylation to IP6 2396.8888888888887 prot_Q99321 + 6-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0093 6PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 1106.9444444444443 prot_Q12494 + 6-diphospho-1D-myo-inositol pentakisphosphate + ATP + H+ --> 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + ADP 0.0 @@ -120,9 +120,9 @@ r_0094 8-amino-7-oxononanoate synthase 1.1329040404040405 prot_standard + H+ + L r_0095_EXP_1 acetaldehyde condensation 0.27589605734767025 prot_P26263 + 2.0 acetaldehyde --> (R)-acetoin 0.0 r_0095_EXP_2 acetaldehyde condensation 0.11780651340996169 prot_P06169 + 2.0 acetaldehyde --> (R)-acetoin 0.0 r_0095_EXP_3 acetaldehyde condensation 0.27738351254480287 prot_P16467 + 2.0 acetaldehyde --> (R)-acetoin 0.0 -r_0096 acetohydroxy acid isomeroreductase 0.6734669095324833 prot_P06168 + 2-acetyllactic acid + H+ + NADPH --> (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) 0.06773178437260949 +r_0096 acetohydroxy acid isomeroreductase 0.6734669095324833 prot_P06168 + 2-acetyllactic acid + H+ + NADPH --> (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) 0.06773178437260591 r_0097_EXP_1 acetolactate synthase 0.16199092088197148 prot_P07342 + 0.07346952010376134 prot_P25605 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.0 -r_0097_EXP_2 acetolactate synthase 0.08099546044098574 prot_P07342 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.06773178437260949 +r_0097_EXP_2 acetolactate synthase 0.08099546044098574 prot_P07342 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.06773178437260591 r_0099 acetyl-CoA ACP transacylase 0.2585296857817232 prot_P32463 + acetyl-CoA + ACP1 --> acetyl-ACP + coenzyme A 0.0 r_0099_REV acetyl-CoA ACP transacylase (reversible) 0.29722261474049355 prot_P32463 + acetyl-ACP + coenzyme A --> acetyl-CoA + ACP1 0.0 r_0100 acetyl-CoA C-acyltransferase (palmitoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxooctadecanoyl-CoA + coenzyme A --> acetyl-CoA + palmitoyl-CoA 0.0 @@ -130,16 +130,16 @@ r_0101 acetyl-CoA C-acyltransferase (tetracosanoyl-CoA) 0.839527027027027 prot_P r_0102 acetyl-CoA C-acyltransferase (myristoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxopalmitoyl-CoA + coenzyme A --> acetyl-CoA + myristoyl-CoA 0.0 r_0103 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.0 r_0103_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA 0.0 -r_0104 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.02212645946904527 +r_0104 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.022126459469172997 r_0104_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA 0.0 r_0105 acetyl-CoA C-acyltransferase (lauroyl-CoA) 0.839527027027027 prot_P27796 + 3-oxotetradecanoyl-CoA + coenzyme A --> acetyl-CoA + lauroyl-CoA 0.0 r_0106 acetyl-CoA C-acyltransferase (octanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxodecanoyl-CoA + coenzyme A --> acetyl-CoA + octanoyl-CoA 0.0 r_0107 acetyl-CoA C-acyltransferase (decanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxolauroyl-CoA + coenzyme A --> acetyl-CoA + decanoyl-CoA 0.0 r_0108 acetyl-Coa carboxylase 8.46937908496732 prot_P32874 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.0 -r_0109 acetyl-CoA carboxylase, reaction 2.608229839040149 prot_P48445 + 8.55097579839999 prot_Q00955 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.11839681828543867 +r_0109 acetyl-CoA carboxylase, reaction 2.608229839040149 prot_P48445 + 8.55097579839999 prot_Q00955 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.11839681828545526 r_0111 acetyl-CoA hydrolase 2.24640342822161 prot_P32316 + acetyl-CoA + H2O --> acetate + coenzyme A + H+ 0.0 r_0112_EXP_1 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 -r_0112_EXP_2 acetyl-CoA synthetase 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.14904230274284952 +r_0112_EXP_2 acetyl-CoA synthetase 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.14904230274286487 r_0113 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 r_0114 acetyl-CoA synthetase nuclear 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 r_0115 acetylglutamate kinase 3.4224025974025976 prot_Q01217 + ATP + N-acetyl-L-glutamate --> ADP + N-acetyl-L-gamma-glutamyl phosphate 0.0194296205196944 @@ -160,7 +160,7 @@ r_0125 acyl-CoA oxidase (tetradecanoyl-CoA) 2.7176949941792783 prot_P13711 + myr r_0126 acyl-CoA:sterol acyltransferase (oleoyl-CoA:episterol), ER membrane 65.94767724903261 prot_P25628 + oleoyl-CoA + episterol --> coenzyme A + episteryl oleate 0.0 r_0126_REV acyl-CoA:sterol acyltransferase (oleoyl-CoA:episterol), ER membrane (reversible) 3.9740642147807406 prot_P25628 + coenzyme A + episteryl oleate --> oleoyl-CoA + episterol 0.0 r_0127_EXP_1 acyl-CoA:sterol acyltransferase (oleoyl-CoA:ergosterol), ER membrane 64.38822905167784 prot_P25628 + oleoyl-CoA + ergosterol --> coenzyme A + ergosteryl oleate 0.0 -r_0127_EXP_2 acyl-CoA:sterol acyltransferase (oleoyl-CoA:ergosterol), ER membrane 20.961725602079696 prot_P53629 + oleoyl-CoA + ergosterol --> coenzyme A + ergosteryl oleate 0.0010294532204957055 +r_0127_EXP_2 acyl-CoA:sterol acyltransferase (oleoyl-CoA:ergosterol), ER membrane 20.961725602079696 prot_P53629 + oleoyl-CoA + ergosterol --> coenzyme A + ergosteryl oleate 0.0010294532200153638 r_0128 acyl-CoA:sterol acyltransferase (oleoyl-CoA:fecosterol), ER membrane 65.94767724903261 prot_P25628 + oleoyl-CoA + fecosterol --> coenzyme A + fecosteryl oleate 0.0 r_0128_REV acyl-CoA:sterol acyltransferase (oleoyl-CoA:fecosterol), ER membrane (reversible) 3.9740642147807406 prot_P25628 + coenzyme A + fecosteryl oleate --> oleoyl-CoA + fecosterol 0.0 r_0129 acyl-CoA:sterol acyltransferase (oleoyl-CoA:lanosterol), ER membrane 57.54568671113769 prot_P25628 + oleoyl-CoA + lanosterol --> coenzyme A + lanosteryl oleate 0.0 @@ -169,7 +169,7 @@ r_0130_REV acyl-CoA:sterol acyltransferase (oleoyl-CoA:zymosterol), ER membrane r_0131 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:episterol), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + episterol --> coenzyme A + episteryl palmitoleate 0.0 r_0131_REV acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:episterol), ER membrane (reversible) 3.9740642147807406 prot_P25628 + coenzyme A + episteryl palmitoleate --> palmitoleoyl-CoA(4-) + episterol 0.0 r_0132_EXP_1 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane 64.38822905167784 prot_P25628 + palmitoleoyl-CoA(4-) + ergosterol --> coenzyme A + ergosteryl palmitoleate 0.0 -r_0132_EXP_2 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + ergosterol --> coenzyme A + ergosteryl palmitoleate -5.016278191438683e-13 +r_0132_EXP_2 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + ergosterol --> coenzyme A + ergosteryl palmitoleate 0.0 r_0132_REV_EXP_1 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane (reversible) 2.799291523044568 prot_P25628 + coenzyme A + ergosteryl palmitoleate --> palmitoleoyl-CoA(4-) + ergosterol 0.0 r_0132_REV_EXP_2 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:ergosterol), ER membrane (reversible) 1.8538886920531146 prot_P53629 + coenzyme A + ergosteryl palmitoleate --> palmitoleoyl-CoA(4-) + ergosterol 0.0 r_0133 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:fecosterol), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + fecosterol --> coenzyme A + fecosteryl palmitoleate 0.0 @@ -184,23 +184,23 @@ r_0138 adenine deaminase 2.0017676767676766 prot_P53909 + adenine + H+ + H2O --> r_0139_EXP_1 adenine phosphoribosyltransferase 0.5950339406931047 prot_P36973 + adenine + PRPP --> AMP + diphosphate 0.0 r_0139_EXP_2 adenine phosphoribosyltransferase 0.6129272359175896 prot_P49435 + adenine + PRPP --> AMP + diphosphate 0.0 r_0140 adenosine deaminase 2.0017676767676766 prot_P53909 + adenosine + H+ + H2O --> ammonium + inosine 0.0 -r_0142 adenosine kinase 0.3962091503267974 prot_P47143 + adenosine + ATP --> ADP + AMP + H+ 0.01408362661089796 +r_0142 adenosine kinase 0.3962091503267974 prot_P47143 + adenosine + ATP --> ADP + AMP + H+ 0.014058985178287188 r_0143 adenosine monophosphate deaminase 21.282895302745313 prot_P15274 + AMP + H+ + H2O --> ammonium + IMP 0.0 -r_0144 adenosylhomocysteinase 0.023732367149758453 prot_P39954 + H2O + S-adenosyl-L-homocysteine --> adenosine + L-homocysteine 0.01406462661028238 -r_0145 adenosylmethionine decarboxylase 7.554248366013072 prot_P21182 + H+ + S-adenosyl-L-methionine --> carbon dioxide + S-adenosylmethioninamine 1.9000000614987463e-05 +r_0144 adenosylhomocysteinase 0.023732367149758453 prot_P39954 + H2O + S-adenosyl-L-homocysteine --> adenosine + L-homocysteine 0.014039985177675776 +r_0145 adenosylmethionine decarboxylase 7.554248366013072 prot_P21182 + H+ + S-adenosyl-L-methionine --> carbon dioxide + S-adenosylmethioninamine 1.9000000611411882e-05 r_0146 adenosylmethionine-8-amino-7-oxononanoate transaminase 14.919166666666667 prot_P50277 + 8-amino-7-oxononanoate + S-adenosyl-L-methionine --> 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate 0.0 r_0146_REV adenosylmethionine-8-amino-7-oxononanoate transaminase (reversible) 14.919166666666667 prot_P50277 + 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate --> 8-amino-7-oxononanoate + S-adenosyl-L-methionine 0.0 r_0147 adenylate cyclase 0.013758091787439614 prot_P08678 + ATP --> 3',5'-cyclic AMP + diphosphate 0.0 r_0148_EXP_1 adenylate kinase 0.007176741835638936 prot_Q12055 + AMP + ATP --> 2.0 ADP 0.39469217767454956 -r_0148_EXP_2 adenylate kinase 0.007660602615122228 prot_P07170 + AMP + ATP --> 2.0 ADP 0.31955687757478457 +r_0148_EXP_2 adenylate kinase 0.007660602615122228 prot_P07170 + AMP + ATP --> 2.0 ADP 0.3195322361421758 r_0149 adenylate kinase 10.450950897581233 prot_P26364 + AMP + ATP --> 2.0 ADP 0.0 r_0150 adenylate kinase (GTP) 10.495327582667667 prot_P26364 + AMP + GTP --> ADP + GDP 0.0 r_0150_REV adenylate kinase (GTP) (reversible) 2.5045140533551153 prot_P26364 + ADP + GDP --> AMP + GTP 0.0 -r_0151 adenylosuccinate lyase (AICAR) 0.04493076162215628 prot_Q05911 + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole --> AICAR + fumarate 0.010240306385261255 -r_0152 adenylosuccinate lyase 0.04493076162215628 prot_Q05911 + adenylo-succinate --> AMP + fumarate 0.013797191947419062 +r_0151 adenylosuccinate lyase (AICAR) 0.04493076162215628 prot_Q05911 + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole --> AICAR + fumarate 0.010240306385253828 +r_0152 adenylosuccinate lyase 0.04493076162215628 prot_Q05911 + adenylo-succinate --> AMP + fumarate 0.013797191947411636 r_0152_REV adenylosuccinate lyase (reversible) 5.221264367816092 prot_Q05911 + AMP + fumarate --> adenylo-succinate 0.0 -r_0153 adenylosuccinate synthase 2.4383333333333335 prot_P80210 + GTP + IMP + L-aspartate --> adenylo-succinate + GDP + 2.0 H+ + phosphate 0.013797191947419062 -r_0154 adenylyl-sulfate kinase 1.4558080808080807 prot_Q02196 + 5'-adenylyl sulfate + ATP --> 3'-phospho-5'-adenylyl sulfate + ADP + H+ 0.01192491661357767 +r_0153 adenylosuccinate synthase 2.4383333333333335 prot_P80210 + GTP + IMP + L-aspartate --> adenylo-succinate + GDP + 2.0 H+ + phosphate 0.013797191947411636 +r_0154 adenylyl-sulfate kinase 1.4558080808080807 prot_Q02196 + 5'-adenylyl sulfate + ATP --> 3'-phospho-5'-adenylyl sulfate + ADP + H+ 0.011924916613574097 r_0155 ADP-ribose 2,3-cyclic phosphodiesterase 0.00789952718676123 prot_P53314 + 2',3'-cyclic AMP + H2O --> adenosine 2'-phosphate + H+ 0.0 r_0156 alanine glyoxylate aminotransferase 0.08886132315521629 prot_P43567 + glyoxylate + L-alanine --> L-glycine + pyruvate 0.0 r_0157 alanyl-tRNA synthetase 0.25476620370370373 prot_P40825 + ATP + L-alanine + tRNA(Ala) --> Ala-tRNA(Ala) + AMP + diphosphate 0.0347736630768556 @@ -235,11 +235,11 @@ r_0170_EXP_2 aldehyde dehydrogenase (2-phenylethanol, NAD) 0.006814054134343373 r_0171_EXP_1 aldehyde dehydrogenase (2-phenylethanol, NADP) 1.6815384615384616 prot_P25377 + H+ + NADPH + phenylacetaldehyde --> 2-phenylethanol + NADP(+) 0.0 r_0171_EXP_2 aldehyde dehydrogenase (2-phenylethanol, NADP) 0.012227777777777778 prot_Q04894 + H+ + NADPH + phenylacetaldehyde --> 2-phenylethanol + NADP(+) 0.0 r_0172_EXP_1 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.483596214511041 prot_P47771 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 0.0 -r_0172_EXP_2 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.06410300925925926 prot_P54114 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 1.9000000614987463e-05 -r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.1371175061292761 +r_0172_EXP_2 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.06410300925925926 prot_P54114 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 1.9000000611411882e-05 +r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.13711750612929502 r_0174 aldehyde dehydrogenase (acetylaldehyde, NAD) 1.6231765567058962 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_0175_EXP_1 aldehyde dehydrogenase (acetylaldehyde, NADP) 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.0 -r_0175_EXP_2 aldehyde dehydrogenase (acetylaldehyde, NADP) 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH -3.767912003883756e-13 +r_0175_EXP_2 aldehyde dehydrogenase (acetylaldehyde, NADP) 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.0 r_0176 aldehyde dehydrogenase (indole-3-acetaldehyde, NAD) 2.9233283159832175 prot_P46367 + H2O + indol-3-ylacetaldehyde + NAD --> 2.0 H+ + indole-3-acetate + NADH 0.0 r_0177 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + H2O + indol-3-ylacetaldehyde + NADP(+) --> 2.0 H+ + indole-3-acetate + NADPH 0.0 r_0178_EXP_1 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 2.027300005914026 prot_P40047 + H2O + indol-3-ylacetaldehyde + NADP(+) --> 2.0 H+ + indole-3-acetate + NADPH 0.0 @@ -294,8 +294,8 @@ r_0199_EXP_1 amidase 0.002363959719142646 prot_P22580 + 4-guanidinobutanamide + r_0199_EXP_2 amidase 0.002263428815277111 prot_Q03557 + 4-guanidinobutanamide + H2O --> 4-guanidinobutanoic acid + ammonium 0.0 r_0200 Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing) 0.062476381011109826 prot_standard + aminoacetone + H2O + oxygen --> ammonium + hydrogen peroxide + methylglyoxal 0.0 r_0201 Aminobutyraldehyde dehydrogenase 6.571504396261395 prot_P46367 + 4-aminobutanal + H2O + NAD --> gamma-aminobutyrate + 2.0 H+ + NADH 0.0 -r_0202 anthranilate phosphoribosyltransferase 2.8570423609142406 prot_P07285 + anthranilate + PRPP --> diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate 0.004463981443244593 -r_0203 anthranilate synthase 0.11426731078904992 prot_P00899 + 0.1076670692431562 prot_P00937 + chorismate + L-glutamine --> anthranilate + H+ + L-glutamate + pyruvate 0.004463981443244593 +r_0202 anthranilate phosphoribosyltransferase 2.8570423609142406 prot_P07285 + anthranilate + PRPP --> diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate 0.004463981443244646 +r_0203 anthranilate synthase 0.11426731078904992 prot_P00899 + 0.1076670692431562 prot_P00937 + chorismate + L-glutamine --> anthranilate + H+ + L-glutamate + pyruvate 0.004463981443244646 r_0204 Ap4A hydrolase 0.16307795442894646 prot_P49775 + H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate --> 2.0 ADP + 2.0 H+ 0.0 r_0204_REV Ap4A hydrolase (reversible) 0.1607002693067822 prot_P49775 + 2.0 ADP + 2.0 H+ --> H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate 0.0 r_0205 arabinose reductase 0.01001051779935275 prot_P38715 + H+ + L-arabinose + NADPH --> L-arabinitol + NADP(+) 0.0 @@ -310,50 +310,50 @@ r_0211_EXP_1 asparagine synthase (glutamine-hydrolysing) 1.9523939064200218 prot r_0211_EXP_2 asparagine synthase (glutamine-hydrolysing) 1.948676097207109 prot_P49089 + ATP + H2O + L-aspartate + L-glutamine --> AMP + diphosphate + H+ + L-asparagine + L-glutamate 0.019146806720785902 r_0212 Asparaginyl-tRNA synthetase 1.710863586358636 prot_P38707 + ATP + L-asparagine + tRNA(Asn) --> AMP + Asn-tRNA(Asn) + diphosphate 0.019146806720785902 r_0213 asparaginyl-tRNA synthetase, miotchondrial 1.5617436743674367 prot_P25345 + ATP + L-asparagine + tRNA(Asn) --> AMP + Asn-tRNA(Asn) + diphosphate 0.0 -r_0214 aspartate carbamoyltransferase 0.1632300826005862 prot_P07259 + carbamoyl phosphate + L-aspartate --> H+ + N-carbamoyl-L-aspartate + phosphate 0.01072683361457144 -r_0215 aspartate kinase 0.0711086637298091 prot_P10869 + ATP + L-aspartate --> 4-phospho-L-aspartate + ADP 0.035442099443413526 +r_0214 aspartate carbamoyltransferase 0.1632300826005862 prot_P07259 + carbamoyl phosphate + L-aspartate --> H+ + N-carbamoyl-L-aspartate + phosphate 0.010726833614579986 +r_0215 aspartate kinase 0.0711086637298091 prot_P10869 + ATP + L-aspartate --> 4-phospho-L-aspartate + ADP 0.03544209944340995 r_0216 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.0 -r_0216_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.1328188533055588 +r_0216_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.1328188533055489 r_0217 aspartate transaminase 0.021473880597014924 prot_Q01802 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.0 r_0218 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.0 r_0218_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.0 -r_0219 aspartate-semialdehyde dehydrogenase 26.415673633916466 prot_P13663 + 4-phospho-L-aspartate + H+ + NADPH --> L-aspartate 4-semialdehyde + NADP(+) + phosphate 0.035442099443413526 +r_0219 aspartate-semialdehyde dehydrogenase 26.415673633916466 prot_P13663 + 4-phospho-L-aspartate + H+ + NADPH --> L-aspartate 4-semialdehyde + NADP(+) + phosphate 0.03544209944340995 r_0220 Aspartyl-tRNA synthetase 0.7351388888888889 prot_P04802 + ATP + L-aspartate + tRNA(Asp) --> AMP + Asp-tRNA(Asp) + diphosphate 0.0240359946744132 r_0221 Aspartyl-tRNA synthetase 0.8733912037037037 prot_P15179 + ATP + L-aspartate + tRNA(Asp) --> AMP + Asp-tRNA(Asp) + diphosphate 0.0 r_0222 ATP adenylyltransferase 0.10660011574074074 prot_P22108 + ADP + ATP + H+ --> P(1),P(4)-bis(5'-adenosyl) tetraphosphate + phosphate 0.0 r_0223 ATP adenylyltransferase 0.10559317129629629 prot_P16550 + ADP + GTP + H+ --> P1-(5'-adenosyl),P4-(5'-guanosyl) tetraphosphate + phosphate 0.0 r_0224 ATP adenylyltransferase 0.10559317129629629 prot_P16550 + GDP + GTP + H+ --> P(1),P(4)-bis(5'-guanosyl) tetraphosphate + phosphate 0.0 r_0225 ATP phosphoribosyltransferase 0.8298868312757202 prot_P00498 + ATP + PRPP --> 5-phosphoribosyl-ATP + diphosphate 0.008356708763266002 -r_0226 ATP synthase 0.5394232482136998 prot_P00830 + 0.09548902616935218 prot_P00854 + 0.019105024583592853 prot_P00856 + 0.08835499603456501 prot_P05626 + 0.5769704298154636 prot_P07251 + 0.07486465662145093 prot_P09457 + 0.022127306899204155 prot_P21306 + 0.06500696272775239 prot_P30902 + 0.11272358287031914 prot_P38077 + 0.25461333861919777 prot_P61829 + 0.0356898398095424 prot_P81449 + 0.021946823156143762 prot_P81450 + 0.024722991276672712 prot_P81451 + 0.03712058366362115 prot_Q06405 + 0.05585151467068882 prot_Q12165 + 0.04240055352878791 prot_Q12233 + 0.04636135130831326 prot_Q12349 + ADP + 3.0 H+ + phosphate --> ATP + 2.0 H+ + H2O 6.660316576553777 +r_0226 ATP synthase 0.028401930104729925 prot_P00830 + 0.005027726661784965 prot_P00854 + 0.0010059254484659976 prot_P00856 + 0.004652102834068531 prot_P05626 + 0.03037887943165331 prot_P07251 + 0.0039418040503784385 prot_P09457 + 0.0011650558740993167 prot_P21306 + 0.0034227727815375154 prot_P30902 + 0.005935167482008843 prot_P38077 + 0.013406004044396558 prot_P61829 + 0.0018791558188794555 prot_P81449 + 0.0011555529713742 prot_P81450 + 0.0013017248932914508 prot_P81451 + 0.0019544879204821996 prot_Q06405 + 0.0029407164432997735 prot_Q12165 + 0.002232491020204252 prot_Q12233 + 0.0024410365400081785 prot_Q12349 + ADP + 3.0 H+ + phosphate --> ATP + 2.0 H+ + H2O 6.66095045173968 r_0226_REV ATP synthase (reversible) 0.3805138888888889 prot_P00830 + 0.06735879629629629 prot_P00854 + 0.013476851851851853 prot_P00856 + 0.06232638888888889 prot_P05626 + 0.407 prot_P07251 + 0.05281018518518518 prot_P09457 + 0.015608796296296296 prot_P21306 + 0.045856481481481484 prot_P30902 + 0.0795162037037037 prot_P38077 + 0.17960648148148148 prot_P61829 + 0.025175925925925925 prot_P81449 + 0.015481481481481481 prot_P81450 + 0.017439814814814814 prot_P81451 + 0.026185185185185186 prot_Q06405 + 0.03939814814814815 prot_Q12165 + 0.029909722222222223 prot_Q12233 + 0.03270370370370371 prot_Q12349 + ATP + 2.0 H+ + H2O --> ADP + 3.0 H+ + phosphate 0.0 r_0227_EXP_1 ATPase, plasma membrane 4.61199074074074 prot_P05030 + 0.20837962962962964 prot_P32903 + 0.22444444444444445 prot_P40975 + ATP + H2O --> ADP + H+ + phosphate 0.0 r_0227_EXP_2 ATPase, plasma membrane 4.730185185185185 prot_P19657 + 0.20837962962962964 prot_P32903 + 0.22444444444444445 prot_P40975 + ATP + H2O --> ADP + H+ + phosphate 0.0 -r_0227_EXP_3 ATPase, plasma membrane 0.023208010335917312 prot_P40009 + ATP + H2O --> ADP + H+ + phosphate 0.5966537561338539 +r_0227_EXP_3 ATPase, plasma membrane 0.023208010335917312 prot_P40009 + ATP + H2O --> ADP + H+ + phosphate 0.5966548158028474 r_0228 beta-1,4 mannosyltransferase 63.94951949233543 prot_P16661 + GDP-alpha-D-mannose + N,N'-diacetylchitobiosyldiphosphodolichol --> beta-D-mannosyldiacetylchitobiosyldiphosphodolichol + GDP + H+ 0.0 r_0229 biotin synthase 0.8370103916866507 prot_P32451 + dethiobiotin + polysulphur --> biotin + 2.0 H+ 0.0 r_0229_REV biotin synthase (reversible) 0.8370103916866507 prot_P32451 + biotin + 2.0 H+ --> dethiobiotin + polysulphur 0.0 r_0230 biotin-[acetyl-CoA-carboxylase] ligase 4.713765432098766e-05 prot_P48445 + ATP + biotin + H+ --> biotinyl-5'-AMP + diphosphate 0.0 -r_0231 C-14 sterol reductase 4.194445624507709 prot_P32462 + 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H+ + NADPH --> 14-demethyllanosterol + NADP(+) 0.003687743244840878 +r_0231 C-14 sterol reductase 4.194445624507709 prot_P32462 + 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H+ + NADPH --> 14-demethyllanosterol + NADP(+) 0.003687743244862164 r_0233 C-22 sterol desaturase (NADP) 100.21895424836602 prot_P54781 + ergosta-5,7,24(28)-trien-3beta-ol + H+ + NADPH + oxygen --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2.0 H2O + NADP(+) 0.0 -r_0234 C-3 sterol dehydrogenase 3.093923129380329 prot_P53199 + NADP(+) + zymosterol intermediate 1c --> carbon dioxide + NADPH + zymosterol intermediate 2 0.003687743244840878 -r_0235 C-3 sterol dehydrogenase (4-methylzymosterol) 8.806624430682128 prot_P53199 + 4beta-methylzymosterol-4alpha-carboxylic acid + NAD --> 3-dehydro-4-methylzymosterol + carbon dioxide + NADH 0.003687743244840878 -r_0236 C-3 sterol keto reductase (4-methylzymosterol) 15.116057838660579 prot_Q12452 + 3-dehydro-4-methylzymosterol + H+ + NADPH --> 4alpha-methylzymosterol + NADP(+) 0.003687743244840878 -r_0237 C-3 sterol keto reductase (zymosterol) 15.116057838660579 prot_Q12452 + H+ + NADPH + zymosterol intermediate 2 --> NADP(+) + zymosterol 0.003687743244840878 -r_0238 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + 4alpha-methylzymosterol + H+ + NADPH + oxygen --> H2O + NADP(+) + zymosterol intermediate 1a 0.003687743244840878 -r_0239 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + H+ + NADPH + oxygen + zymosterol intermediate 1a --> 2.0 H2O + NADP(+) + zymosterol intermediate 1b 0.003687743244840878 -r_0240 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + NADPH + oxygen + zymosterol intermediate 1b --> H2O + NADP(+) + zymosterol intermediate 1c 0.003687743244840878 -r_0241 C-4 sterol methyl oxidase (4,4-dimethylzymosterol) 0.511770482603816 prot_P53045 + 14-demethyllanosterol + 5.0 H+ + 3.0 oxygen + 6.0 ferrocytochrome b5 --> 4beta-methylzymosterol-4alpha-carboxylic acid + 4.0 H2O + 6.0 ferricytochrome b5 0.003687743244840878 +r_0234 C-3 sterol dehydrogenase 3.093923129380329 prot_P53199 + NADP(+) + zymosterol intermediate 1c --> carbon dioxide + NADPH + zymosterol intermediate 2 0.003687743244862164 +r_0235 C-3 sterol dehydrogenase (4-methylzymosterol) 8.806624430682128 prot_P53199 + 4beta-methylzymosterol-4alpha-carboxylic acid + NAD --> 3-dehydro-4-methylzymosterol + carbon dioxide + NADH 0.003687743244862164 +r_0236 C-3 sterol keto reductase (4-methylzymosterol) 15.116057838660579 prot_Q12452 + 3-dehydro-4-methylzymosterol + H+ + NADPH --> 4alpha-methylzymosterol + NADP(+) 0.003687743244862164 +r_0237 C-3 sterol keto reductase (zymosterol) 15.116057838660579 prot_Q12452 + H+ + NADPH + zymosterol intermediate 2 --> NADP(+) + zymosterol 0.003687743244862164 +r_0238 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + 4alpha-methylzymosterol + H+ + NADPH + oxygen --> H2O + NADP(+) + zymosterol intermediate 1a 0.003687743244862164 +r_0239 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + H+ + NADPH + oxygen + zymosterol intermediate 1a --> 2.0 H2O + NADP(+) + zymosterol intermediate 1b 0.003687743244862164 +r_0240 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + NADPH + oxygen + zymosterol intermediate 1b --> H2O + NADP(+) + zymosterol intermediate 1c 0.003687743244862164 +r_0241 C-4 sterol methyl oxidase (4,4-dimethylzymosterol) 0.511770482603816 prot_P53045 + 14-demethyllanosterol + 5.0 H+ + 3.0 oxygen + 6.0 ferrocytochrome b5 --> 4beta-methylzymosterol-4alpha-carboxylic acid + 4.0 H2O + 6.0 ferricytochrome b5 0.003687743244862164 r_0242 C-5 sterol desaturase 24.953439493862604 prot_P32353 + episterol + H+ + NADPH + oxygen --> ergosta-5,7,24(28)-trien-3beta-ol + 2.0 H2O + NADP(+) 0.0 r_0243 C-8 sterol isomerase 11.181301444435384 prot_P32352 + fecosterol --> episterol 0.0 -r_0244 C-s24 sterol reductase 1.5624148864343401 prot_P25340 + ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + NADPH --> ergosterol + NADP(+) 0.003687743244840878 +r_0244 C-s24 sterol reductase 1.5624148864343401 prot_P25340 + ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + NADPH --> ergosterol + NADP(+) 0.003687743244862164 r_0249 CAAX farnesyltransferase 4.1518225763666585 prot_P22007 + 3.231511956720494 prot_P29703 + 4-hydroxybenzoate + nonaprenyl diphosphate --> diphosphate + nonaprenyl 4-hydroxybenzoate 0.0 -r_0250_EXP_1 carbamoyl-phosphate synthase (glutamine-hydrolysing) 0.01089245390373571 prot_P07259 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.030156454134265848 +r_0250_EXP_1 carbamoyl-phosphate synthase (glutamine-hydrolysing) 0.01089245390373571 prot_P07259 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.030156454134274386 r_0250_EXP_2 carbamoyl-phosphate synthase (glutamine-hydrolysing) 3.661790780141844 prot_P03965 + 1.34048463356974 prot_P07258 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.0 r_0252_EXP_1 carnitine O-acetyltransferase 0.016201655041376033 prot_P80235 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 r_0252_EXP_2 carnitine O-acetyltransferase 0.05053501564945227 prot_P40017 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 r_0253 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 r_0254 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + coenzyme A + O-acetylcarnitine --> (R)-carnitine + acetyl-CoA 0.0 -r_0255 catalase 6.339124460149195e-06 prot_P06115 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 9.500000307493731e-06 +r_0255 catalase 6.339124460149195e-06 prot_P06115 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 9.500000305705941e-06 r_0256 catalase 5.747447978013349e-06 prot_P15202 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0 r_0259 ceramide-1 hydroxylase (24C) 0.035359375 prot_P38992 + ceramide-1 (C24) + H+ + NADPH + oxygen --> ceramide-2 (C24) + H2O + NADP(+) 0.0 r_0260 ceramide-1 hydroxylase (24C) 0.03895920138888889 prot_Q03529 + ceramide-1 (C24) + H+ + NADPH + oxygen --> ceramide-2' (C24) + H2O + NADP(+) 0.0 @@ -372,11 +372,11 @@ r_0271_EXP_2 chitin deacetylase 0.01794357473933983 prot_Q06703 + chitin + H2O - r_0272_EXP_1 chitin synthase 80.72709323101475 prot_P29465 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0 r_0272_EXP_2 chitin synthase 13.190119547029806 prot_P14180 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0023610000000000003 r_0272_EXP_3 chitin synthase 188.53265572369114 prot_P08004 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0 -r_0273 choline kinase 7.224074074074074 prot_P20485 + ATP + choline --> ADP + choline phosphate + H+ 0.002827701568400936 -r_0274 choline phosphate cytididyltransferase 0.4121287954621288 prot_P13259 + choline phosphate + CTP + H+ --> CDP-choline + diphosphate 0.002827701568400936 -r_0278 chorismate mutase 0.02288935056940597 prot_P32178 + chorismate --> prephenate 0.0289821618819572 -r_0279 chorismate synthase 0.3336437908496732 prot_P28777 + 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid --> chorismate + phosphate 0.03345248332545636 -r_0280 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.09627284473818554 +r_0273 choline kinase 7.224074074074074 prot_P20485 + ATP + choline --> ADP + choline phosphate + H+ 0.003153248722256296 +r_0274 choline phosphate cytididyltransferase 0.4121287954621288 prot_P13259 + choline phosphate + CTP + H+ --> CDP-choline + diphosphate 0.003153248722256296 +r_0278 chorismate mutase 0.02288935056940597 prot_P32178 + chorismate --> prephenate 0.028982161881957208 +r_0279 chorismate synthase 0.3336437908496732 prot_P28777 + 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid --> chorismate + phosphate 0.03345248332545642 +r_0280 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.09627284473801356 r_0280_REV cis-aconitate(3-) to isocitrate (reversible) 0.16582750582750583 prot_P19414 + isocitrate --> cis-aconitate + H2O 0.0 r_0281_EXP_1 cis-prenyltransferase step 01 40.954572225982666 prot_P35196 + farnesyl diphosphate + isopentenyl diphosphate --> diphosphate + geranylgeranyl diphosphate 0.0 r_0281_EXP_2 cis-prenyltransferase step 01 30.078354060470264 prot_Q03175 + farnesyl diphosphate + isopentenyl diphosphate --> diphosphate + geranylgeranyl diphosphate 0.0 @@ -420,28 +420,28 @@ r_0298_EXP_1 cis-prenyltransferase step 18 40.954572225982666 prot_P35196 + icos r_0298_EXP_2 cis-prenyltransferase step 18 30.078354060470264 prot_Q03175 + icosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + henicosaprenyl diphosphate 0.0 r_0299_EXP_1 cis-prenyltransferase step 19 40.954572225982666 prot_P35196 + henicosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + docosaprenyl diphosphate 0.0 r_0299_EXP_2 cis-prenyltransferase step 19 30.078354060470264 prot_Q03175 + henicosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + docosaprenyl diphosphate 0.0 -r_0300_EXP_1 citrate synthase 0.10489895415585436 prot_P00890 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.8843969840815697 +r_0300_EXP_1 citrate synthase 0.10489895415585436 prot_P00890 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.8844944643290789 r_0300_EXP_2 citrate synthase 0.10578556263269638 prot_P43635 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.0 r_0301 citrate synthase, peroxisomal 1.275124007936508 prot_P08679 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.0 -r_0302 citrate to cis-aconitate(3-) 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.09627284473818554 +r_0302 citrate to cis-aconitate(3-) 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.09627284473801356 r_0302_REV citrate to cis-aconitate(3-) (reversible) 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> citrate 0.0 -r_0303 citrate to cis-aconitate(3-), cytoplasmic 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.7881241393433842 +r_0303 citrate to cis-aconitate(3-), cytoplasmic 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.788221619591065 r_0303_REV citrate to cis-aconitate(3-), cytoplasmic (reversible) 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> citrate 0.0 r_0304 coproporphyrinogen oxidase (O2 required) 616.2091503267974 prot_P11353 + coproporphyrinogen III + 2.0 H+ + oxygen --> 2.0 carbon dioxide + 2.0 H2O + protoporphyrinogen 0.0 r_0306_EXP_1 CTP synthase (glutamine) 0.5634796238244514 prot_P28274 + ATP + H2O + L-glutamine + UTP --> ADP + CTP + 2.0 H+ + L-glutamate + phosphate 0.0 r_0306_EXP_2 CTP synthase (glutamine) 0.5617467781260884 prot_P38627 + ATP + H2O + L-glutamine + UTP --> ADP + CTP + 2.0 H+ + L-glutamate + phosphate 0.0 r_0307_EXP_1 CTP synthase (NH3) 0.5634796238244514 prot_P28274 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.0 -r_0307_EXP_2 CTP synthase (NH3) 0.5617467781260884 prot_P38627 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.004927623923655561 +r_0307_EXP_2 CTP synthase (NH3) 0.5617467781260884 prot_P38627 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.004927623923664107 r_0308_EXP_1 cystathionine b-lyase 11.285409035409035 prot_P43623 + H2O + L-cystathionine --> ammonium + L-homocysteine + pyruvate 0.0 r_0308_EXP_2 cystathionine b-lyase 15.820512820512821 prot_P53101 + H2O + L-cystathionine --> ammonium + L-homocysteine + pyruvate 0.0 -r_0309 cystathionine beta-synthase 0.7237984496124031 prot_P32582 + L-homocysteine + L-serine --> H2O + L-cystathionine 0.0037750499662992584 -r_0310 cystathionine g-lyase 6.5288520564763655 prot_P31373 + H2O + L-cystathionine --> 2-oxobutanoate + ammonium + L-cysteine 0.0037750499662992584 +r_0309 cystathionine beta-synthase 0.7237984496124031 prot_P32582 + L-homocysteine + L-serine --> H2O + L-cystathionine 0.003775049966295682 +r_0310 cystathionine g-lyase 6.5288520564763655 prot_P31373 + H2O + L-cystathionine --> 2-oxobutanoate + ammonium + L-cysteine 0.003775049966295682 r_0311 cystathionine gamma-synthase 0.16609504132231406 prot_P47164 + L-cysteine + O-acetyl-L-homoserine --> acetate + H+ + L-cystathionine 0.0 r_0312 cysteine synthase 0.05827586206896552 prot_P06106 + hydrogen sulfide + O-acetyl-L-serine --> acetate + L-cysteine 0.0 r_0313 cysteinyl-tRNA synthetase 0.1712245696400626 prot_P53852 + ATP + L-cysteine + tRNA(Cys) --> AMP + Cys-tRNA(Cys) + diphosphate 0.00375594996568427 r_0314 cytidine deaminase 0.34727251593751957 prot_Q06549 + cytidine + H+ + H2O --> ammonium + uridine 0.0 r_0315 cytidine kinase (GTP) 3.6366925064599482 prot_P27515 + cytidine + GTP --> CMP + GDP + H+ 0.0 -r_0317 cytochrome P450 lanosterol 14-alpha-demethylase (NADP) 2.53 prot_P10614 + 3.1988333333333334 prot_P16603 + 2.0 H+ + lanosterol + 3.0 NADPH + 3.0 oxygen --> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 4.0 H2O + 3.0 NADP(+) 0.003687743244840878 +r_0317 cytochrome P450 lanosterol 14-alpha-demethylase (NADP) 2.53 prot_P10614 + 3.1988333333333334 prot_P16603 + 2.0 H+ + lanosterol + 3.0 NADPH + 3.0 oxygen --> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 4.0 H2O + 3.0 NADP(+) 0.003687743244862164 r_0318 cytosine deaminase 0.028606209150326797 prot_Q12178 + cytosine + H+ + H2O --> ammonium + uracil 0.0 r_0319 D-arabinono-1,4-lactone oxidase 0.790723019670388 prot_P54783 + D-arabinono-1,4-lactone + oxygen --> dehydro-D-arabinono-1,4-lactone + H+ + hydrogen peroxide 0.0 r_0320 D-arabinose 1-dehydrogenase (NAD) 4.371122252366052 prot_Q04212 + D-arabinose + NAD --> D-arabinono-1,4-lactone + H+ + NADH 0.0 @@ -474,14 +474,14 @@ r_0346 dihydrofolate synthase 1.4510179534077177 prot_Q12676 + 7,8-dihydropteroa r_0347 dihydroneopterin aldolase 25.866666666666667 prot_P53848 + 7,8-dihydroneopterin --> 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + glycolaldehyde 6.3400002545677125e-06 r_0348 dihydroneopterin monophosphate dephosphorylase 1.3136097495034373 prot_Q12154 + 7,8-dihydroneopterin 3'-phosphate + H2O --> 7,8-dihydroneopterin + phosphate 0.0 r_0349 dihydroorotase 5.893713450292398 prot_P20051 + (S)-dihydroorotate + H2O --> H+ + N-carbamoyl-L-aspartate 0.0 -r_0349_REV dihydroorotase (reversible) 0.17974406991260924 prot_P20051 + H+ + N-carbamoyl-L-aspartate --> (S)-dihydroorotate + H2O 0.01072683361457144 +r_0349_REV dihydroorotase (reversible) 0.17974406991260924 prot_P20051 + H+ + N-carbamoyl-L-aspartate --> (S)-dihydroorotate + H2O 0.010726833614579986 r_0350 dihydropteroate synthase 237.30886850152908 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + 4-aminobenzoate --> 7,8-dihydropteroate + H2O 6.3400002545677125e-06 r_0351 dihydropteroate synthase 237.30886850152908 prot_P53848 + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + 4-aminobenzoate --> 7,8-dihydropteroate + diphosphate 0.0 -r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.23036133098798006 prot_P39522 + (R)-2,3-dihydroxy-3-methylbutanoate --> 3-methyl-2-oxobutanoate + H2O 0.06773178437260949 +r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.23036133098798006 prot_P39522 + (R)-2,3-dihydroxy-3-methylbutanoate --> 3-methyl-2-oxobutanoate + H2O 0.06773178437260591 r_0353 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate) 1.419625112917796 prot_P39522 + (2R,3R)-2,3-dihydroxy-3-methylpentanoate --> (S)-3-methyl-2-oxopentanoate + H2O 0.0265490320174191 r_0354_EXP_1 dihydroxyacetone kinase 0.7185562956795263 prot_P43550 + ATP + glycerone --> ADP + dihydroxyacetone phosphate + H+ 0.0 r_0354_EXP_2 dihydroxyacetone kinase 0.719388935146637 prot_P54838 + ATP + glycerone --> ADP + dihydroxyacetone phosphate + H+ 0.0 -r_0355 dimethylallyltranstransferase 10.222979797979797 prot_P08524 + isopentenyl diphosphate + prenyl diphosphate(3-) --> diphosphate + geranyl diphosphate 0.007375486489681757 +r_0355 dimethylallyltranstransferase 10.222979797979797 prot_P08524 + isopentenyl diphosphate + prenyl diphosphate(3-) --> diphosphate + geranyl diphosphate 0.007375486489724328 r_0356 diphosphoglyceromutase 0.013314525462962964 prot_P00950 + 1,3-bisphospho-D-glycerate --> 2,3-bisphospho-D-glyceric acid + H+ 0.0 r_0356_REV diphosphoglyceromutase (reversible) 0.013314525462962964 prot_P00950 + 2,3-bisphospho-D-glyceric acid + H+ --> 1,3-bisphospho-D-glycerate 0.0 r_0357 diphosphoinositol-1,3,4,6-tetrakisphosphate diphosphohydrolase 2396.8888888888887 prot_Q99321 + 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + 3.0 H2O --> 3.0 H+ + myo-inositol 1,3,4,5,6-pentakisphosphate + 3.0 phosphate 0.0 @@ -498,7 +498,7 @@ r_0364_EXP_1 dUTP diphosphatase 0.006082204603017289 prot_P47119 + dUTP + H2O -- r_0364_EXP_2 dUTP diphosphatase 0.4429108796296296 prot_P33317 + dUTP + H2O --> diphosphate + dUMP + H+ 0.0 r_0365 endopolygalacturonase 1.7035361842105263 prot_P47180 + H2O + pectin --> D-galacturonate 0.0 r_0366_EXP_1 enolase 0.05715942028985507 prot_P0CX11 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 -r_0366_EXP_2 enolase 0.056541062801932364 prot_P00924 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 1.6419486914684494 +r_0366_EXP_2 enolase 0.056541062801932364 prot_P00924 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 1.6420461717163628 r_0366_EXP_3 enolase 0.18354460093896713 prot_P00925 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 r_0366_EXP_4 enolase 0.057141304347826084 prot_P42222 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 r_0366_EXP_5 enolase 0.05715942028985507 prot_P0CX10 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 @@ -529,33 +529,33 @@ r_0412_REV fatty-acid--CoA ligase (tetradecanoate) (reversible) 33.7398594538402 r_0436 ferrochelatase 8.096586782861293 prot_P16622 + iron(2+) + protoporphyrin --> ferroheme b + 2.0 H+ 0.0 r_0437_EXP_1 ferrocytochrome-c:hydrogen-peroxide oxidoreductase 0.003481111111111111 prot_P00045 + 0.011209166666666666 prot_P00431 + 2.0 ferrocytochrome c + hydrogen peroxide --> 2.0 ferricytochrome c + 2.0 H2O 0.0 r_0437_EXP_2 ferrocytochrome-c:hydrogen-peroxide oxidoreductase 0.003383888888888889 prot_P00044 + 0.011209166666666666 prot_P00431 + 2.0 ferrocytochrome c + hydrogen peroxide --> 2.0 ferricytochrome c + 2.0 H2O 0.0 -r_0438_EXP_1 ferrocytochrome-c:oxygen oxidoreductase 0.0025292407050374562 prot_P00045 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003470743090051798 prot_P00425 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_2 ferrocytochrome-c:oxygen oxidoreductase 0.0025292407050374562 prot_P00045 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003459239202389243 prot_P00424 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_3 ferrocytochrome-c:oxygen oxidoreductase 0.002458602798337559 prot_P00044 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003470743090051798 prot_P00425 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_4 ferrocytochrome-c:oxygen oxidoreductase 0.002458602798337559 prot_P00044 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003459239202389243 prot_P00424 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 10.700184086790783 -r_0438_EXP_5 ferrocytochrome-c:oxygen oxidoreductase 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.0014052906981468086 prot_P07255 + 0.006870848273403699 prot_P19516 + 0.003495163623510905 prot_P38824 + 0.0028410566074698585 prot_P47081 + 0.007194975353860941 prot_P53239 + 0.004794901106789011 prot_Q04935 + 0.0022412398682924474 prot_Q3E731 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0439_EXP_1 ubiquinol:ferricytochrome c reductase 0.011983406387337664 prot_P00045 + 0.01650156750927913 prot_P00127 + 0.013927410950492583 prot_P00128 + 0.041744940093010934 prot_P00163 + 0.03256422793814109 prot_P07143 + 0.04802924800695788 prot_P07256 + 0.03870605839025327 prot_P07257 + 0.022342187219928544 prot_P08067 + 0.010494564722393141 prot_P08525 + 0.007148734930716276 prot_P22289 + 0.008216837782188999 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 0.7791147508464885 -r_0439_EXP_2 ubiquinol:ferricytochrome c reductase 0.01164872778571237 prot_P00044 + 0.01650156750927913 prot_P00127 + 0.013927410950492583 prot_P00128 + 0.041744940093010934 prot_P00163 + 0.03256422793814109 prot_P07143 + 0.04802924800695788 prot_P07256 + 0.03870605839025327 prot_P07257 + 0.022342187219928544 prot_P08067 + 0.010494564722393141 prot_P08525 + 0.007148734930716276 prot_P22289 + 0.008216837782188999 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 4.570977292548904 -r_0440 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 9.999999748822042e-07 +r_0438_EXP_1 ferrocytochrome-c:oxygen oxidoreductase 0.0010737358074137757 prot_P00045 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0014734307915811285 prot_P00425 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_2 ferrocytochrome-c:oxygen oxidoreductase 0.0010737358074137757 prot_P00045 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.001468547058655611 prot_P00424 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_3 ferrocytochrome-c:oxygen oxidoreductase 0.0010437479736605981 prot_P00044 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0014734307915811285 prot_P00425 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_4 ferrocytochrome-c:oxygen oxidoreductase 0.0010437479736605981 prot_P00044 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.001468547058655611 prot_P00424 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 10.700959017236919 +r_0438_EXP_5 ferrocytochrome-c:oxygen oxidoreductase 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0005965865326382158 prot_P07255 + 0.0029168737494090794 prot_P19516 + 0.001483798014107227 prot_P38824 + 0.0012061106735528025 prot_P47081 + 0.00305447506657366 prot_P53239 + 0.0020355741551656946 prot_Q04935 + 0.0009514711252258203 prot_Q3E731 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0439_EXP_1 ubiquinol:ferricytochrome c reductase 0.0023972378816698543 prot_P00045 + 0.003301079965207204 prot_P00127 + 0.002786129089253226 prot_P00128 + 0.00835092698389556 prot_P00163 + 0.006514358128013637 prot_P07143 + 0.009608080459664334 prot_P07256 + 0.007743009493634883 prot_P07257 + 0.004469475191925961 prot_P08067 + 0.0020994003950946896 prot_P08525 + 0.0014300790299524282 prot_P22289 + 0.001643749211393956 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 0.0 +r_0439_EXP_2 ubiquinol:ferricytochrome c reductase 0.002330286616222643 prot_P00044 + 0.003301079965207204 prot_P00127 + 0.002786129089253226 prot_P00128 + 0.00835092698389556 prot_P00163 + 0.006514358128013637 prot_P07143 + 0.009608080459664334 prot_P07256 + 0.007743009493634883 prot_P07257 + 0.004469475191925961 prot_P08067 + 0.0020994003950946896 prot_P08525 + 0.0014300790299524282 prot_P22289 + 0.001643749211393956 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 5.350479508618459 +r_0440 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 9.99999974737875e-07 r_0441 FMN reductase 0.10556051587301588 prot_Q07923 + FMN + 2.0 H+ + NADH --> FMNH2 + NAD 0.0 r_0442 FMN reductase 0.10556051587301588 prot_Q07923 + FMN + 2.0 H+ + NADPH --> FMNH2 + NADP(+) 0.0 r_0443 formaldehyde dehydrogenase 8.906684027777779 prot_P32771 + formaldehyde + glutathione + NAD --> H+ + NADH + S-formylglutathione 0.0 r_0445 formate dehydrogenase 0.012874691358024692 prot_Q08911 + formate + NAD --> carbon dioxide + NADH 0.0 -r_0446 formate-tetrahydrofolate ligase 0.3982132433666004 prot_P07245 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.0046200832346292905 +r_0446 formate-tetrahydrofolate ligase 0.3982132433666004 prot_P07245 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.004620083234456938 r_0446_REV formate-tetrahydrofolate ligase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.0 -r_0447 formate-tetrahydrofolate ligase 0.42978473739580797 prot_P09440 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate -1.9009937395932097e-13 +r_0447 formate-tetrahydrofolate ligase 0.42978473739580797 prot_P09440 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.0 r_0447_REV formate-tetrahydrofolate ligase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.0 r_0448_EXP_1 fructose-2,6-bisphosphate 2-phosphatase 5.915698747876994 prot_Q06137 + beta-D-fructose 2,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 r_0448_EXP_2 fructose-2,6-bisphosphate 2-phosphatase 146.09722222222223 prot_P32604 + beta-D-fructose 2,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 r_0449 fructose-bisphosphatase 0.15249083373186673 prot_P09201 + D-fructose 1,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 -r_0450 fructose-bisphosphate aldolase 0.166213415970673 prot_P14540 + D-fructose 1,6-bisphosphate --> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate 0.830900089675868 +r_0450 fructose-bisphosphate aldolase 0.166213415970673 prot_P14540 + D-fructose 1,6-bisphosphate --> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate 0.8309307105009115 r_0450_REV fructose-bisphosphate aldolase (reversible) 0.33864102564102566 prot_P14540 + dihydroxyacetone phosphate + glyceraldehyde 3-phosphate --> D-fructose 1,6-bisphosphate 0.0 -r_0451 fumarase 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.7475000981339569 +r_0451 fumarase 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.7475975783812654 r_0451_REV fumarase (reversible) 0.014265163714439076 prot_P08417 + (S)-malate --> fumarate + H2O 0.0 -r_0452 fumarase, cytoplasmic 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.043467118852374725 +r_0452 fumarase, cytoplasmic 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.04346711885255633 r_0452_REV fumarase, cytoplasmic (reversible) 0.014265163714439076 prot_P08417 + (S)-malate --> fumarate + H2O 0.0 -r_0453 dihydoorotic acid dehydrogenase 1.1372875816993464 prot_P28272 + (S)-dihydroorotate + fumarate --> orotate + succinate 0.01072683361457144 -r_0454 fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.0675302217184317 +r_0453 dihydoorotic acid dehydrogenase 1.1372875816993464 prot_P28272 + (S)-dihydroorotate + fumarate --> orotate + succinate 0.010726833614579986 +r_0454 fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.06753022171843157 r_0454_REV fumarate reductase (reversible) 0.9170995670995671 prot_P32614 + FAD + H+ + succinate --> FADH2 + fumarate 0.0 r_0455 soluble fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.0 r_0455_REV soluble fumarate reductase (reversible) 0.9170995670995671 prot_P32614 + FAD + H+ + succinate --> FADH2 + fumarate 0.0 @@ -564,23 +564,23 @@ r_0458 galactokinase 0.7217737917289487 prot_P04385 + ATP + D-galactose --> ADP r_0459 galactose-1-phosphate uridylyltransferase 0.3270447530864197 prot_P08431 + alpha-D-galactose 1-phosphate + H+ + UTP --> diphosphate + UDP-D-galactose 0.0 r_0460 gamma-glutamylcysteine synthetase 0.00213319158216116 prot_P32477 + ATP + L-cysteine + L-glutamate --> ADP + H+ + L-gamma-glutamyl-L-cysteine + phosphate 1e-07 r_0461 geranylgeranyltranstransferase 0.6162073031087573 prot_standard + geranylgeranyl diphosphate + isopentenyl diphosphate --> diphosphate + pentaprenyl diphosphate 0.0 -r_0462 geranyltranstransferase 10.222979797979797 prot_P08524 + geranyl diphosphate + isopentenyl diphosphate --> farnesyl diphosphate + diphosphate 0.007375486489681757 +r_0462 geranyltranstransferase 10.222979797979797 prot_P08524 + geranyl diphosphate + isopentenyl diphosphate --> farnesyl diphosphate + diphosphate 0.007375486489724328 r_0463 glucan 1,4-alpha-glucosidase 44.78465926163774 prot_Q06625 + glycogen + H2O --> D-glucose 0.0 r_0464 glucan 1,4-alpha-glucosidase, vacuole 0.05205199864498645 prot_P08019 + glycogen + H2O --> D-glucose 0.0 r_0465 glucosamine-6-phosphate deaminase 0.1225001911377612 prot_standard + alpha-D-glucosamine 6-phosphate + H2O --> ammonium + D-fructose 6-phosphate 0.0 -r_0466 glucose 6-phosphate dehydrogenase 0.025250210703750525 prot_P11412 + D-glucose 6-phosphate + NADP(+) --> 6-O-phosphono-D-glucono-1,5-lactone + H+ + NADPH 0.31375894768961987 -r_0467 glucose-6-phosphate isomerase 0.024857664233576642 prot_P12709 + D-glucose 6-phosphate --> D-fructose 6-phosphate 0.7285193324569972 +r_0466 glucose 6-phosphate dehydrogenase 0.025250210703750525 prot_P11412 + D-glucose 6-phosphate + NADP(+) --> 6-O-phosphono-D-glucono-1,5-lactone + H+ + NADPH 0.31367026422156963 +r_0467 glucose-6-phosphate isomerase 0.024857664233576642 prot_P12709 + D-glucose 6-phosphate --> D-fructose 6-phosphate 0.7286090755941029 r_0467_REV glucose-6-phosphate isomerase (reversible) 0.024857664233576642 prot_P12709 + D-fructose 6-phosphate --> D-glucose 6-phosphate 0.0 r_0468 glutamate 5-kinase 1.0234809027777778 prot_P32264 + ATP + L-glutamate --> ADP + L-gamma-glutamyl phosphate 0.08551233665859126 r_0469 glutamate decarboxylase 34.13511276639768 prot_Q04792 + H+ + L-glutamate --> carbon dioxide + gamma-aminobutyrate 0.0 r_0470 glutamate dehydrogenase (NAD) 1.4390277777777778 prot_P33327 + H2O + L-glutamate + NAD --> 2-oxoglutarate + ammonium + H+ + NADH 0.0 r_0471_EXP_1 glutamate dehydrogenase (NADP) 0.5307169380898228 prot_P39708 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.0 -r_0471_EXP_2 glutamate dehydrogenase (NADP) 0.5301073734280234 prot_P07262 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.5531992458382973 +r_0471_EXP_2 glutamate dehydrogenase (NADP) 0.5301073734280234 prot_P07262 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.5531440005820027 r_0472 glutamate synthase (NADH2) 0.9448492063492063 prot_Q12680 + 2-oxoglutarate + H+ + L-glutamine + NADH --> 2.0 L-glutamate + NAD 0.0 r_0473 glutamate-5-semialdehyde dehydrogenase 0.2646166013940106 prot_P54885 + H+ + L-gamma-glutamyl phosphate + NADPH --> L-glutamic 5-semialdehyde + NADP(+) + phosphate 0.08551233665859126 r_0475_EXP_1 glutaminase 0.0011171565228214292 prot_P43544 + H2O + L-glutamine --> ammonium + L-glutamate 0.0 r_0475_EXP_2 glutaminase 0.0011205348411301363 prot_P53823 + H2O + L-glutamine --> ammonium + L-glutamate 0.0 -r_0476 glutamine synthetase 0.029297138047138047 prot_P32288 + ammonium + ATP + L-glutamate --> ADP + H+ + L-glutamine + phosphate 0.10449512025996062 +r_0476 glutamine synthetase 0.029297138047138047 prot_P32288 + ammonium + ATP + L-glutamate --> ADP + H+ + L-glutamine + phosphate 0.10449512025995442 r_0477 glutamine-fructose-6-phosphate transaminase 0.6263458528951487 prot_P14742 + D-fructose 6-phosphate + L-glutamine --> alpha-D-glucosamine 6-phosphate + L-glutamate 0.0023610000000000003 r_0478 glutaminyl-tRNA synthetase 15.369603878657363 prot_P13188 + ATP + L-glutamine + tRNA(Gln) --> AMP + diphosphate + Gln-tRNA(Gln) 0.0141160332291015 r_0479 glutamyl-tRNA synthetase 4.974688861932783 prot_P46655 + ATP + L-glutamate + tRNA(Glu) --> AMP + diphosphate + Glu-tRNA(Glu) 0.029648731201628798 @@ -599,7 +599,7 @@ r_0483_EXP_6 glutathione peridoxase 0.3697285294019552 prot_P36014 + 2.0 glutath r_0484 glutathione peroxidase, mitochondria 1.0350179133060056 prot_Q02784 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0485 glutathione synthetase 0.2818939393939394 prot_Q08220 + ATP + L-gamma-glutamyl-L-cysteine + L-glycine --> ADP + glutathione + H+ + phosphate 1e-07 r_0486_EXP_1 glyceraldehyde-3-phosphate dehydrogenase 1.091178266178266 prot_P00359 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 0.0 -r_0486_EXP_2 glyceraldehyde-3-phosphate dehydrogenase 0.1416581138487952 prot_P00360 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 1.7300502454646378 +r_0486_EXP_2 glyceraldehyde-3-phosphate dehydrogenase 0.1416581138487952 prot_P00360 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 1.7300924804562703 r_0486_EXP_3 glyceraldehyde-3-phosphate dehydrogenase 0.5962574850299401 prot_P00358 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 0.0 r_0486_REV_EXP_1 glyceraldehyde-3-phosphate dehydrogenase (reversible) 1.091178266178266 prot_P00359 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 r_0486_REV_EXP_2 glyceraldehyde-3-phosphate dehydrogenase (reversible) 0.3424329501915709 prot_P00360 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 @@ -609,19 +609,19 @@ r_0488 glycerol kinase 0.013277445109780439 prot_P32190 + ATP + glycerol --> ADP r_0489_EXP_1 glycerol-3-phosphatase 0.6923038630027878 prot_P40106 + glycerol 3-phosphate + H2O --> glycerol + phosphate 0.0 r_0489_EXP_2 glycerol-3-phosphatase 0.6956142970927918 prot_P41277 + glycerol 3-phosphate + H2O --> glycerol + phosphate 0.0 r_0490 glycerol-3-phosphate dehydrogenase (fad) 0.6038455121788456 prot_P32191 + FAD + glycerol 3-phosphate + H+ --> dihydroxyacetone phosphate + FADH2 0.0 -r_0491_EXP_1 glycerol-3-phosphate dehydrogenase (NAD) 0.10538102261553589 prot_Q00055 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.00696055227704984 +r_0491_EXP_1 glycerol-3-phosphate dehydrogenase (NAD) 0.10538102261553589 prot_Q00055 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.006949997779490293 r_0491_EXP_2 glycerol-3-phosphate dehydrogenase (NAD) 0.1214896755162242 prot_P41911 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.0 r_0492 glycerol-3-phosphate dehydrogenase (NAD) 0.1214896755162242 prot_P41911 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.0 r_0497 glycerophosphodiester phosphodiesterase (glycerophosphocholine) 0.174260101010101 prot_Q02979 + H2O + sn-glycero-3-phosphocholine --> choline + glycerol 3-phosphate + H+ 0.0 -r_0499 glycinamide ribotide transformylase 0.1634722222222222 prot_P04161 + 10-formyl-THF + 5-phospho-ribosyl-glycineamide --> 5'-phosphoribosyl-N-formylglycineamide + H+ + THF 0.010240426385265499 +r_0499 glycinamide ribotide transformylase 0.1634722222222222 prot_P04161 + 10-formyl-THF + 5-phospho-ribosyl-glycineamide --> 5'-phosphoribosyl-N-formylglycineamide + H+ + THF 0.01024042638525807 r_0500 glycine C-acetyltransferase 0.062476381011109826 prot_standard + coenzyme A + L-2-amino-3-oxobutanoate --> acetyl-CoA + L-glycine 0.0 r_0501 glycine cleavage system 0.17131712790948955 prot_P09624 + 0.05961049407152449 prot_P39726 + 0.14105353380868527 prot_P48015 + 0.3630330791773559 prot_P49095 + L-glycine + NAD + THF --> 5,10-methylenetetrahydrofolate + ammonium + carbon dioxide + NADH 0.0 -r_0502 glycine hydroxymethyltransferase 0.0226640625 prot_P37291 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 0.04679173155053662 +r_0502 glycine hydroxymethyltransferase 0.0226640625 prot_P37291 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 0.046767090118086926 r_0502_REV glycine hydroxymethyltransferase (reversible) 63.06521739130435 prot_P37291 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF 0.0 -r_0503 glycine hydroxymethyltransferase 0.023301215277777777 prot_P37292 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 1.8993175132773497e-05 -r_0503_REV glycine hydroxymethyltransferase (reversible) 64.83816425120773 prot_P37292 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF -6.8256723133404744e-09 +r_0503 glycine hydroxymethyltransferase 0.023301215277777777 prot_P37292 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 1.899317493916812e-05 +r_0503_REV glycine hydroxymethyltransferase (reversible) 64.83816425120773 prot_P37292 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF -6.825672243763543e-09 r_0504 glycine-cleavage complex (lipoamide) 0.023116760828625234 prot_P09624 + 0.00804357130628317 prot_P39726 + 0.019033127889060093 prot_P48015 + 0.048986046909775725 prot_P49095 + H+ + L-glycine + lipoamide --> carbon dioxide + S(8)-aminomethyldihydrolipoamide 0.0 -r_0505_EXP_1 glycine-cleavage complex (lipoamide) 0.016688295637127672 prot_P09624 + 0.005806760598195526 prot_P39726 + 0.013740266963292547 prot_P48015 + 0.0353636756890372 prot_P49095 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 0.7475000981339569 +r_0505_EXP_1 glycine-cleavage complex (lipoamide) 0.016688295637127672 prot_P09624 + 0.005806760598195526 prot_P39726 + 0.013740266963292547 prot_P48015 + 0.0353636756890372 prot_P49095 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 0.7475975783814619 r_0505_EXP_2 glycine-cleavage complex (lipoamide) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 0.0 r_0506 glycine-cleavage complex (lipoylprotein) 0.04357695209331861 prot_P09624 + 0.015162778387145652 prot_P39726 + 0.0358789757940712 prot_P48015 + 0.09234263551254228 prot_P49095 + L-glycine + lipoylprotein --> carbon dioxide + S(8)-aminomethyldihydrolipoylprotein 0.0 r_0507 glycine-cleavage complex (lipoylprotein) 0.2838103427329358 prot_P09624 + 0.0987529674315879 prot_P39726 + 0.23367454417683617 prot_P48015 + 0.6014141369399599 prot_P49095 + H+ + S(8)-aminomethyldihydrolipoylprotein + THF --> 5,10-methylenetetrahydrofolate + ammonium + dihydrolipoylprotein 0.0 @@ -650,7 +650,7 @@ r_0523_EXP_2 GPI-anchor assembly, step 9 0.03254362265000563 prot_Q07830 + 6-O-{ r_0523_REV_EXP_1 GPI-anchor assembly, step 9 (reversible) 0.007109647641562535 prot_Q06636 + 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone --> 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone 0.0 r_0523_REV_EXP_2 GPI-anchor assembly, step 9 (reversible) 0.03254362265000563 prot_Q07830 + 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone --> 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone 0.0 r_0524 GTP cyclohydrolase I 197.7849002849003 prot_P51601 + GTP + H2O --> 7,8-dihydroneopterin 3'-triphosphate + formate + H+ 6.3400002545677125e-06 -r_0525 GTP cyclohydrolase II 0.024647633744855967 prot_P38066 + GTP + 3.0 H2O --> 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + diphosphate + formate + 2.0 H+ 9.999999710999519e-05 +r_0525 GTP cyclohydrolase II 0.024647633744855967 prot_P38066 + GTP + 3.0 H2O --> 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + diphosphate + formate + 2.0 H+ 9.999999710998968e-05 r_0526 guanine deaminase 1.7229712858926343 prot_Q07729 + guanine + H+ + H2O --> 9H-xanthine + ammonium 0.0 r_0527 guanine phosphoribosyltransferase 0.09123207301173403 prot_Q04178 + guanine + PRPP --> diphosphate + GMP 0.0 r_0528 guanylate kinase 0.014549492385786802 prot_P15454 + ATP + GMP --> ADP + GDP 0.00034634000876395364 @@ -686,10 +686,10 @@ r_0543_EXP_2 homocitrate synthase 21.204303979830723 prot_P48570 + 2-oxoglutarat r_0544_EXP_1 homocysteine S-methyltransferase 26.83845029239766 prot_Q12525 + L-homocysteine + S-adenosyl-L-methionine --> H+ + L-methionine + S-adenosyl-L-homocysteine 0.0 r_0544_EXP_2 homocysteine S-methyltransferase 26.80482456140351 prot_Q08985 + L-homocysteine + S-adenosyl-L-methionine --> H+ + L-methionine + S-adenosyl-L-homocysteine 0.0 r_0545 homoisocitrate dehydrogenase 0.6547222222222222 prot_P40495 + homoisocitrate + NAD --> 2-oxoadipic acid + carbon dioxide + NADH 0.032939964005654 -r_0546 homoserine dehydrogenase (NADH) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADH --> L-homoserine + NAD 0.035442099443413526 +r_0546 homoserine dehydrogenase (NADH) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADH --> L-homoserine + NAD 0.03544209944340995 r_0547 homoserine dehydrogenase (NADP) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADPH --> L-homoserine + NADP(+) 0.0 r_0548 homoserine kinase 0.263562091503268 prot_P17423 + ATP + L-homoserine --> ADP + H+ + O-phospho-L-homoserine 0.023517302829840103 -r_0549 homoserine O-trans-acetylase 0.9806103801169591 prot_P08465 + acetyl-CoA + L-homoserine --> coenzyme A + O-acetyl-L-homoserine 0.011924796613573426 +r_0549 homoserine O-trans-acetylase 0.9806103801169591 prot_P08465 + acetyl-CoA + L-homoserine --> coenzyme A + O-acetyl-L-homoserine 0.011924796613569849 r_0550_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.3160087719298246 prot_Q04120 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0550_EXP_2 hydrogen peroxide reductase (thioredoxin) 0.1642543859649123 prot_P22217 + 0.3160087719298246 prot_Q04120 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0551 hydrogen peroxide reductase (thioredoxin) 0.07592592592592592 prot_P25372 + 0.15517676767676766 prot_P34227 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 @@ -701,8 +701,8 @@ r_0555 hydroxybenzoate octaprenyltransferase 0.8535401716463751 prot_P32378 + 4- r_0556 hydroxyethylthiazole kinase 12.64725296618268 prot_P41835 + 5-(2-hydroxyethyl)-4-methylthiazole + ATP --> 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ 0.0 r_0557 hydroxymethylbilane synthase 163.0 prot_P28789 + H2O + 4.0 porphobilinogen --> 4.0 ammonium + preuroporphyrinogen 0.0 r_0558_EXP_1 hydroxymethylglutaryl CoA reductase 1.5450320512820512 prot_P12684 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.0 -r_0558_EXP_2 hydroxymethylglutaryl CoA reductase 1.544150641025641 prot_P12683 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.02212645946904527 -r_0560 hydroxymethylglutaryl CoA synthase 3.322101449275362 prot_P54839 + acetoacetyl-CoA + acetyl-CoA + H2O --> 3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ 0.02212645946904527 +r_0558_EXP_2 hydroxymethylglutaryl CoA reductase 1.544150641025641 prot_P12683 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.022126459469172997 +r_0560 hydroxymethylglutaryl CoA synthase 3.322101449275362 prot_P54839 + acetoacetyl-CoA + acetyl-CoA + H2O --> 3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ 0.022126459469172997 r_0561_EXP_1 hydroxymethylpyrimidine kinase (ATP) 39.57945736434109 prot_Q08224 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 r_0561_EXP_2 hydroxymethylpyrimidine kinase (ATP) 39.62144702842377 prot_Q08975 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 r_0561_EXP_3 hydroxymethylpyrimidine kinase (ATP) 340.09581877502734 prot_Q06490 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 1.20000004244503e-07 @@ -712,14 +712,14 @@ r_0564 imidazoleglycerol-phosphate dehydratase 0.004728769841269841 prot_P06633 r_0565_EXP_1 IMP dehydrogenase 6.383242999096658 prot_P38697 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0022325586016579916 r_0565_EXP_2 IMP dehydrogenase 6.389453477868112 prot_P50095 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0 r_0565_EXP_3 IMP dehydrogenase 6.367886178861789 prot_P50094 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0025672645994502027 -r_0566 indole-3-glycerol-phosphate synthase 1.550264949662187 prot_P00937 + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ --> 1-C-(indol-3-yl)glycerol 3-phosphate + carbon dioxide + H2O 0.004463981443244593 +r_0566 indole-3-glycerol-phosphate synthase 1.550264949662187 prot_P00937 + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ --> 1-C-(indol-3-yl)glycerol 3-phosphate + carbon dioxide + H2O 0.004463981443244646 r_0567_EXP_1 indole-3-pyruvate decarboxylase 0.27589605734767025 prot_P26263 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 r_0567_EXP_2 indole-3-pyruvate decarboxylase 0.11780651340996169 prot_P06169 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 r_0567_EXP_3 indole-3-pyruvate decarboxylase 0.27738351254480287 prot_P16467 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 -r_0568 inorganic diphosphatase 0.03450854700854701 prot_P00817 + diphosphate + H2O --> H+ + 2.0 phosphate 0.3908794276461818 -r_0569 inorganic diphosphatase 0.03800534188034188 prot_P28239 + diphosphate + H2O --> H+ + 2.0 phosphate 0.5747374154748881 +r_0568 inorganic diphosphatase 0.03450854700854701 prot_P00817 + diphosphate + H2O --> H+ + 2.0 phosphate 0.3906211569867652 +r_0569 inorganic diphosphatase 0.03800534188034188 prot_P28239 + diphosphate + H2O --> H+ + 2.0 phosphate 0.5752649283630253 r_0570_EXP_1 inosine monophosphate cyclohydrolase 2.10859173126615 prot_P54113 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.0 -r_0570_EXP_2 inosine monophosphate cyclohydrolase 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.018597015148527254 +r_0570_EXP_2 inosine monophosphate cyclohydrolase 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.01859701514851983 r_0570_REV_EXP_1 inosine monophosphate cyclohydrolase (reversible) 2.10859173126615 prot_P54113 + H2O + IMP --> phosphoribosyl-formamido-carboxamide 0.0 r_0570_REV_EXP_2 inosine monophosphate cyclohydrolase (reversible) 2.1079780361757106 prot_P38009 + H2O + IMP --> phosphoribosyl-formamido-carboxamide 0.0 r_0571 inositol-1,3,4,5,6-pentakisphosphate 2-kinase 12.457614290039357 prot_Q06667 + ATP + myo-inositol 1,3,4,5,6-pentakisphosphate --> ADP + H+ + myo-inositol hexakisphosphate 0.0 @@ -790,7 +790,7 @@ r_0655 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol-P-ce r_0656 isoamyl acetate-hydrolyzing esterase 6.693496157764181 prot_P41734 + H2O + isoamyl acetate --> acetate + H+ + isoamylol 0.0 r_0657 isobutyl acetate-hydrolyzing esterase 9.93658635305908 prot_P41734 + H2O + isobutyl acetate --> acetate + H+ + isobutanol 0.0 r_0658 isocitrate dehydrogenase (NAD+) 0.5194640522875817 prot_P28241 + 0.5140392156862745 prot_P28834 + isocitrate + NAD --> 2-oxoglutarate + carbon dioxide + NADH 0.0 -r_0659 isocitrate dehydrogenase (NADP) 0.05072113289760349 prot_P41939 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.7881241393433842 +r_0659 isocitrate dehydrogenase (NADP) 0.05072113289760349 prot_P41939 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.788221619591065 r_0659_REV isocitrate dehydrogenase (NADP) (reversible) 2.6395691609977323 prot_P41939 + 2-oxoglutarate + carbon dioxide + NADPH --> isocitrate + NADP(+) 0.0 r_0661 isocitrate dehydrogenase (NADP+), peroxisomal 0.05213071895424837 prot_P53982 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.0 r_0662 isocitrate lyase 1.3133207070707071 prot_P28240 + isocitrate --> glyoxylate + succinate 0.0 @@ -800,13 +800,13 @@ r_0664 isoleucine transaminase 0.011265116279069768 prot_P38891 + 2-oxoglutarate r_0664_REV isoleucine transaminase (reversible) 0.011265116279069768 prot_P38891 + (S)-3-methyl-2-oxopentanoate + L-glutamate --> 2-oxoglutarate + L-isoleucine 0.0 r_0665 isoleucyl-tRNA synthetase 0.4249032614704257 prot_P09436 + ATP + L-isoleucine + tRNA(Ile) --> AMP + diphosphate + Ile-tRNA(Ile) 0.0265490320174191 r_0666 isoleucyl-tRNA synthetase 0.40006218905472635 prot_P48526 + ATP + L-isoleucine + tRNA(Ile) --> AMP + diphosphate + Ile-tRNA(Ile) 0.0 -r_0667 isopentenyl-diphosphate D-isomerase 1.1202472121456402 prot_P15496 + isopentenyl diphosphate --> prenyl diphosphate(3-) 0.007375486489681757 +r_0667 isopentenyl-diphosphate D-isomerase 1.1202472121456402 prot_P15496 + isopentenyl diphosphate --> prenyl diphosphate(3-) 0.007375486489724328 r_0667_REV isopentenyl-diphosphate D-isomerase (reversible) 1.1202472121456402 prot_P15496 + prenyl diphosphate(3-) --> isopentenyl diphosphate 0.0 r_0668 itaconate-CoA ligase (ADP-forming) 0.22156557067271354 prot_P53312 + 0.16549508692365836 prot_P53598 + ATP + coenzyme A + itaconate --> ADP + itaconyl-CoA + phosphate 0.0 r_0668_REV itaconate-CoA ligase (ADP-forming) (reversible) 0.5921843434343435 prot_P53312 + 0.44232323232323234 prot_P53598 + ADP + itaconyl-CoA + phosphate --> ATP + coenzyme A + itaconate 0.0 r_0669 ketol-acid reductoisomerase (2-aceto-2-hydroxybutanoate) 0.6734669095324833 prot_P06168 + (S)-2-acetyl-2-hydroxybutanoate + H+ + NADPH --> (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) 0.0265490320174191 r_0670 kynureninase 1.2721196709441296 prot_Q05979 + H2O + L-kynurenine --> anthranilate + H+ + L-alanine 0.0 -r_0671 kynurenine 3-monooxygenase 7.174192665571977 prot_P38169 + H+ + L-kynurenine + NADPH + oxygen --> 3-hydroxy-L-kynurenine + H2O + NADP(+) 0.0006069999973987722 +r_0671 kynurenine 3-monooxygenase 7.174192665571977 prot_P38169 + H+ + L-kynurenine + NADPH + oxygen --> 3-hydroxy-L-kynurenine + H2O + NADP(+) 0.0006069999973988254 r_0672 L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase 11.932407407407407 prot_P07275 + 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H2O + NAD --> erythro-4-hydroxy-L-glutamic acid + H+ + NADH 0.0 r_0672_REV L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase (reversible) 11.932407407407407 prot_P07275 + erythro-4-hydroxy-L-glutamic acid + H+ + NADH --> 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H2O + NAD 0.0 r_0673 L-4-hydroxyglutamate semialdehyde dehydrogenase 11.932407407407407 prot_P07275 + H2O + L-4-hydroxyglutamic semialdehyde + NAD --> erythro-4-hydroxy-L-glutamic acid + 2.0 H+ + NADH 0.0 @@ -833,11 +833,11 @@ r_0690 L-serine dehydrogenase 0.7363131313131314 prot_Q05016 + L-serine + NADP(+ r_0691 L-sorbitol dehydrogenase (L-sorbose-producing) 0.7983182730923695 prot_P35497 + L-glucitol + NAD --> H+ + L-sorbose + NADH 0.0 r_0692 L-threonine deaminase 0.007720611346848971 prot_P25379 + L-threonine --> 2-oxobutanoate + ammonium 0.0 r_0693 L-threonine deaminase 0.01253948609146629 prot_P00927 + L-threonine --> 2-oxobutanoate + ammonium 0.0 -r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.3527200202735511 prot_P47125 + L-tryptophan + oxygen --> N-formyl-L-kynurenine 0.0006069999973987721 +r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.3527200202735511 prot_P47125 + L-tryptophan + oxygen --> N-formyl-L-kynurenine 0.0006069999973988259 r_0695 L-tyrosine N-formyltransferase 52.20067092135934 prot_P21623 + 10-formyl-THF + L-tyrosine --> H+ + N-formyl-L-tyrosine + THF 0.0 r_0696 lactaldehyde dehydrogenase 0.033859544541667556 prot_Q12068 + (S)-lactaldehyde + H2O + NAD --> (S)-lactate + 2.0 H+ + NADH 0.0 r_0697 lactoylglutathione lyase 0.005679029304029304 prot_P50107 + glutathione + methylglyoxal --> (R)-S-lactoylglutathione 0.0 -r_0698 lanosterol synthase 24.44598824754819 prot_P38604 + (S)-2,3-epoxysqualene --> lanosterol 0.003687743244840878 +r_0698 lanosterol synthase 24.44598824754819 prot_P38604 + (S)-2,3-epoxysqualene --> lanosterol 0.003687743244862164 r_0699 leucine transaminase 0.012875835189309577 prot_P47176 + 2-oxoglutarate + L-leucine --> 4-methyl-2-oxopentanoate + L-glutamate 0.0 r_0699_REV leucine transaminase (reversible) 0.010755813953488373 prot_P47176 + 4-methyl-2-oxopentanoate + L-glutamate --> 2-oxoglutarate + L-leucine 0.0362523293945085 r_0700 leucine transaminase 0.013485523385300667 prot_P38891 + 2-oxoglutarate + L-leucine --> 4-methyl-2-oxopentanoate + L-glutamate 0.0 @@ -858,41 +858,41 @@ r_0708 leukotriene A4 hydrolase 1.0690022111663904 prot_Q10740 + H2O + leukotrie r_0708_REV leukotriene A4 hydrolase (reversible) 4.1321047008547005 prot_Q10740 + leukotriene B4 --> H2O + leukotriene A4 0.0 r_0711 lysyl-tRNA synthetase 0.41307439824945297 prot_P15180 + ATP + L-lysine + tRNA(Lys) --> AMP + diphosphate + Lys-tRNA(Lys) 0.032939964005654 r_0712 lysyl-tRNA synthetase 0.40194505227327987 prot_P32048 + ATP + L-lysine + tRNA(Lys) --> AMP + diphosphate + Lys-tRNA(Lys) 0.0 -r_0713 malate dehydrogenase 0.05201038748832867 prot_P17505 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.8843969840815697 +r_0713 malate dehydrogenase 0.05201038748832867 prot_P17505 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.8844944643289002 r_0713_REV malate dehydrogenase (reversible) 0.05201038748832867 prot_P17505 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.0 r_0714 malate dehydrogenase, cytoplasmic 0.009916009348524686 prot_P22133 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.0 -r_0714_REV malate dehydrogenase, cytoplasmic (reversible) 9.304413377192983e-05 prot_P22133 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.11086735926696215 +r_0714_REV malate dehydrogenase, cytoplasmic (reversible) 9.304413377192983e-05 prot_P22133 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.11086735926678448 r_0715 malate dehydrogenase, peroxisomal 0.009052974973220372 prot_P32419 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.0 r_0715_REV malate dehydrogenase, peroxisomal (reversible) 8.494608918128655e-05 prot_P32419 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.0 r_0716_EXP_1 malate synthase 0.9084780092592593 prot_P21826 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 r_0716_EXP_2 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 r_0717 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 r_0718 malic enzyme (NAD) 0.15417910447761193 prot_P36013 + (S)-malate + NAD --> carbon dioxide + NADH + pyruvate 0.0 -r_0719 malic enzyme (NADP) 0.15417910447761193 prot_P36013 + (S)-malate + NADP(+) --> carbon dioxide + NADPH + pyruvate 0.017437592171724026 +r_0719 malic enzyme (NADP) 0.15417910447761193 prot_P36013 + (S)-malate + NADP(+) --> carbon dioxide + NADPH + pyruvate 0.017437592171705818 r_0721 malonyl-CoA-ACP transacylase 0.0018443121693121694 prot_P32463 + 0.0053845238095238095 prot_Q12283 + H+ + malonyl-CoA + ACP1 --> carboxyacetyl-ACP + coenzyme A 0.0 r_0721_REV malonyl-CoA-ACP transacylase (reversible) 0.0018443121693121694 prot_P32463 + 0.0053845238095238095 prot_Q12283 + carboxyacetyl-ACP + coenzyme A --> H+ + malonyl-CoA + ACP1 0.0 r_0722 mannose-1-phosphate guanylyltransferase 0.056102886960467356 prot_P41940 + D-mannose 1-phosphate + GTP + H+ --> diphosphate + GDP-alpha-D-mannose 0.070204 r_0723 mannose-6-phosphate isomerase 0.6692916666666666 prot_P29952 + D-mannose 6-phosphate --> D-fructose 6-phosphate 0.0 r_0723_REV mannose-6-phosphate isomerase (reversible) 0.09493498817966903 prot_P29952 + D-fructose 6-phosphate --> D-mannose 6-phosphate 0.070204 r_0724 methenyltetrahydrifikate cyclohydrolase 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.0 -r_0724_REV methenyltetrahydrifikate cyclohydrolase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O -1.9009937395932097e-13 -r_0725 methenyltetrahydrofolate cyclohydrolase 1.3619742369207077 prot_P07245 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.024217358299163466 +r_0724_REV methenyltetrahydrifikate cyclohydrolase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O 0.0 +r_0725 methenyltetrahydrofolate cyclohydrolase 1.3619742369207077 prot_P07245 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.02421735829932096 r_0725_REV methenyltetrahydrofolate cyclohydrolase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O 0.0 -r_0726_EXP_1 methionine adenosyltransferase 1.565037037037037 prot_P19358 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.014083626610897959 +r_0726_EXP_1 methionine adenosyltransferase 1.565037037037037 prot_P19358 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.014058985178287188 r_0726_EXP_2 methionine adenosyltransferase 19.92471888698304 prot_P10659 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.0 -r_0727 methionine synthase 24.2238162581693 prot_P05694 + 5-methyltetrahydrofolate + L-homocysteine --> L-methionine + THF 0.02221437325755714 +r_0727 methionine synthase 24.2238162581693 prot_P05694 + 5-methyltetrahydrofolate + L-homocysteine --> L-methionine + THF 0.022189731824949946 r_0728 methionyl-tRNA formyltransferase 95.33547008547009 prot_P32785 + 10-formyl-THF + Met-tRNA(Met) --> fMet-tRNA(fMet) + H+ + THF 0.0 r_0729 methionyl-tRNA synthetase 0.9519777777777778 prot_P00958 + ATP + L-methionine + tRNA(Met) --> AMP + diphosphate + Met-tRNA(Met) 0.00814974664727417 r_0730 methionyl-tRNA synthetase 0.7414888888888889 prot_P22438 + ATP + L-methionine + tRNA(Met) --> AMP + diphosphate + Met-tRNA(Met) 0.0 -r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 3.4304661673761956 prot_Q02046 + 5,10-methylenetetrahydrofolate + NAD --> 5,10-methenyl-THF + NADH 0.024217358299163466 +r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 3.4304661673761956 prot_Q02046 + 5,10-methylenetetrahydrofolate + NAD --> 5,10-methenyl-THF + NADH 0.02421735829932096 r_0732 methylenetetrahydrofolate dehydrogenase (NADP) 3.1493641930417993 prot_P07245 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) 0.0 -r_0733 methylenetetrahydrofolate dehydrogenase (NADP) 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) -1.9009937395932097e-13 +r_0733 methylenetetrahydrofolate dehydrogenase (NADP) 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) 0.0 r_0734 methylisocitrate lyase 1.3673400673400673 prot_Q12031 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> pyruvate + succinate 0.0 -r_0735 mevalonate kinase (atp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + ATP --> (R)-5-phosphomevalonic acid + ADP + H+ 0.02212645946904527 +r_0735 mevalonate kinase (atp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + ATP --> (R)-5-phosphomevalonic acid + ADP + H+ 0.022126459469172997 r_0736 mevalonate kinase (ctp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + CTP --> (R)-5-phosphomevalonic acid + CDP + H+ 0.0 r_0737 mevalonate kinase (gtp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + GTP --> (R)-5-phosphomevalonic acid + GDP + H+ 0.0 r_0738 mevalonate kinase (UTP) 0.4723196881091618 prot_P07277 + (R)-mevalonate + UTP --> (R)-5-phosphomevalonic acid + H+ + UDP 0.0 -r_0739 mevalonate pyrophoshate decarboxylase 2.500907029478458 prot_P32377 + (R)-5-diphosphomevalonic acid + ATP --> ADP + carbon dioxide + isopentenyl diphosphate + phosphate 0.02212645946904527 +r_0739 mevalonate pyrophoshate decarboxylase 2.500907029478458 prot_P32377 + (R)-5-diphosphomevalonic acid + ATP --> ADP + carbon dioxide + isopentenyl diphosphate + phosphate 0.022126459469172997 r_0747_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide A (C24) --> GDP + H+ + mannosylinositol phosphorylceramide A (C24) 0.0 r_0747_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide A (C24) --> GDP + H+ + mannosylinositol phosphorylceramide A (C24) 0.0 r_0748_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide A (C26) --> GDP + H+ + mannosylinositol phosphorylceramide A (C26) 0.0 @@ -913,16 +913,16 @@ r_0755_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 pro r_0755_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide D (C24) --> GDP + H+ + mannosylinositol phosphorylceramide D (C24) 0.0 r_0756_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide D (C26) --> GDP + H+ + mannosylinositol phosphorylceramide D (C26) 0.0 r_0756_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide D (C26) --> GDP + H+ + mannosylinositol phosphorylceramide D (C26) 0.0 -r_0757_EXP_1 myo-inositol 1-phosphatase 0.03326388888888889 prot_Q05533 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0008562816933829467 +r_0757_EXP_1 myo-inositol 1-phosphatase 0.03326388888888889 prot_Q05533 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0008552220243274044 r_0757_EXP_2 myo-inositol 1-phosphatase 0.0340205223880597 prot_P38710 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0 -r_0758 myo-inositol-1-phosphate synthase 1.7257523148148148 prot_P11986 + D-glucose 6-phosphate --> 1D-myo-inositol 1-phosphate 0.0008562816933829209 +r_0758 myo-inositol-1-phosphate synthase 1.7257523148148148 prot_P11986 + D-glucose 6-phosphate --> 1D-myo-inositol 1-phosphate 0.0008552220243274178 r_0759 N-acetyl-g-glutamyl-phosphate reductase 3.4224025974025976 prot_Q01217 + H+ + N-acetyl-L-gamma-glutamyl phosphate + NADPH --> 2-acetamido-5-oxopentanoate + NADP(+) + phosphate 0.0194296205196944 r_0760 N-acetylglucosamine-6-phosphate synthase 0.4886032977691562 prot_P43577 + acetyl-CoA + alpha-D-glucosamine 6-phosphate --> coenzyme A + H+ + N-acetyl-D-glucosamine 6-phosphate 0.0023610000000000003 r_0761_EXP_1 N-acteylglutamate synthase 82.8409090909091 prot_P40360 + acetyl-CoA + L-glutamate --> coenzyme A + H+ + N-acetyl-L-glutamate 0.0 r_0761_EXP_2 N-acteylglutamate synthase 0.6359516214779373 prot_Q04728 + acetyl-CoA + L-glutamate --> coenzyme A + H+ + N-acetyl-L-glutamate 0.0 r_0761_REV_EXP_1 N-acteylglutamate synthase (reversible) 23.365384615384617 prot_P40360 + coenzyme A + H+ + N-acetyl-L-glutamate --> acetyl-CoA + L-glutamate 0.0 r_0761_REV_EXP_2 N-acteylglutamate synthase (reversible) 0.6359516214779373 prot_Q04728 + coenzyme A + H+ + N-acetyl-L-glutamate --> acetyl-CoA + L-glutamate 0.0 -r_0762 N-formyl-L-kynurenine amidohydrolase 0.05174430641821946 prot_Q04066 + H2O + N-formyl-L-kynurenine --> formate + H+ + L-kynurenine 0.0006069999973987721 +r_0762 N-formyl-L-kynurenine amidohydrolase 0.05174430641821946 prot_Q04066 + H2O + N-formyl-L-kynurenine --> formate + H+ + L-kynurenine 0.0006069999973988259 r_0763 N-formyltyrosine oxidase 70.69806925295306 prot_P21595 + 77.40588128458634 prot_P21623 + H+ + 2.0 N-formyl-L-tyrosine + NADPH --> N,N'-diformyldityrosine + NADP(+) 0.0 r_0764 NAD diphosphatase 4835.111111111111 prot_P53164 + H2O + NAD --> AMP + 2.0 H+ + NMN 0.0 r_0765_EXP_1 NAD kinase 18.47685185185185 prot_P32622 + ATP + NAD --> ADP + H+ + NADP(+) 0.0 @@ -935,17 +935,17 @@ r_0767_EXP_2 NAD nucleosidase nuclear 42.186868686868685 prot_P53688 + H2O + NAD r_0767_EXP_3 NAD nucleosidase nuclear 58.28484848484848 prot_P53685 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 r_0767_EXP_4 NAD nucleosidase nuclear 51.03434343434343 prot_P53687 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 r_0767_EXP_5 NAD nucleosidase nuclear 40.38282828282828 prot_P53686 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 -r_0768 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0006071199974030167 +r_0768 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0006071199974030699 r_0769 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0 r_0769_REV NAD synthase (reversible) 3.5019965277777776 prot_P38795 + AMP + diphosphate + H+ + L-glutamate + NAD --> ATP + deamido-NAD(+) + H2O + L-glutamine 0.0 -r_0770_EXP_1 NADH dehydrogenase, cytosolic/mitochondrial 0.034255 prot_Q07500 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 1.7719989660995754 +r_0770_EXP_1 NADH dehydrogenase, cytosolic/mitochondrial 0.034255 prot_Q07500 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 1.7719965103327784 r_0770_EXP_2 NADH dehydrogenase, cytosolic/mitochondrial 0.034874444444444444 prot_P40215 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 0.0 r_0771_EXP_1 NADH kinase 0.9640096618357487 prot_P32622 + ATP + NADH --> ADP + H+ + NADPH 0.0 -r_0771_EXP_2 NADH kinase 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0003270000044719492 +r_0771_EXP_2 NADH kinase 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0003270000044722221 r_0772_EXP_1 NADH kinase mitochondrial 0.9640096618357487 prot_P32622 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0772_EXP_2 NADH kinase mitochondrial 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0772_EXP_3 NADH kinase mitochondrial 0.7979123533471358 prot_Q06892 + ATP + NADH --> ADP + H+ + NADPH 0.0 -r_0773 NADH:ubiquinone oxidoreductase 0.03180555555555555 prot_P32340 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 2.7523359238288574 +r_0773 NADH:ubiquinone oxidoreductase 0.03180555555555555 prot_P32340 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 2.752628364571208 r_0774 NAPRtase 62.59351652704193 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 1.20000004244503e-07 r_0775 NAPRtase 54.465555555555554 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 0.0 r_0781 nicotinamidase 1.8269736842105264 prot_P53184 + H2O + nicotinamide --> ammonium + nicotinate 1.20000004244503e-07 @@ -954,9 +954,9 @@ r_0783_EXP_1 nicotinamide-nucleotide adenylyltransferase 0.15292207792207793 pro r_0783_EXP_2 nicotinamide-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + NMN --> diphosphate + NAD 0.0 r_0784_EXP_1 nicotinamide-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + NMN --> diphosphate + NAD 0.0 r_0784_EXP_2 nicotinamide-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + NMN --> diphosphate + NAD 0.0 -r_0785_EXP_1 nicotinate-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0006071199974030167 +r_0785_EXP_1 nicotinate-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0006071199974030699 r_0785_EXP_2 nicotinate-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0 -r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0006069999973987722 +r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0006069999973988254 r_0787 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0 r_0788 nucleoside diphosphatase 0.25820037372430643 prot_P40009 + ADP + H2O --> AMP + H+ + phosphate 0.0 r_0789 nucleoside diphosphatase 0.19246758812814743 prot_P40009 + GDP + H2O --> GMP + H+ + phosphate 0.0 @@ -964,12 +964,12 @@ r_0790 nucleoside diphosphatase 0.24671061667353386 prot_P40009 + H2O + UDP --> r_0791 nucleoside diphosphatase 0.004121119814331302 prot_P32621 + H2O + UDP --> H+ + phosphate + UMP 0.0 r_0792 nucleoside diphosphatase 0.00661109270913842 prot_P40009 + CDP + H2O --> CMP + H+ + phosphate 0.0 r_0793 nucleoside diphosphatase 0.24979835905993603 prot_P40009 + H2O + IDP --> H+ + IMP + phosphate 0.0 -r_0795 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + CDP --> ADP + CTP 0.004054584475741058 +r_0795 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + CDP --> ADP + CTP 0.004348468136930202 r_0796 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dADP --> ADP + dATP 0.0 r_0797 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dCDP --> ADP + dCTP 0.0 r_0798 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dGDP --> ADP + dGTP 0.0 r_0799 nucleoside diphosphate kinase 0.3585421888053467 prot_P36010 + ATP + dTDP --> ADP + dTTP 0.0 -r_0800 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + GDP --> ADP + GTP 0.08410753194478363 +r_0800 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + GDP --> ADP + GTP 0.0841075319447762 r_0801 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + IDP --> ADP + ITP 0.0 r_0802 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dIDP --> ADP + dITP 0.0 r_0802_REV nucleoside diphosphate kinase (reversible) 0.3585421888053467 prot_P36010 + ADP + dITP --> ATP + dIDP 0.0 @@ -982,9 +982,9 @@ r_0805 nucleoside triphosphatase 0.1930260047281324 prot_P40009 + H2O + UTP --> r_0806 nucleoside triphosphatase 0.00661109270913842 prot_P40009 + CTP + H2O --> CDP + H+ + phosphate 0.0 r_0807 nucleoside triphosphatase 0.00673132000048749 prot_P47119 + H2O + ITP --> H+ + IDP + phosphate 0.0 r_0810 nucleoside-diphosphatase (GDP), Golgi 0.004121119814331302 prot_P32621 + GDP + H2O --> GMP + H+ + phosphate 0.0 -r_0811 nucleoside-diphosphate kinase (ATP:UDP) 0.014855486327448944 prot_P36010 + ATP + UDP --> ADP + UTP 0.15524262392365556 +r_0811 nucleoside-diphosphate kinase (ATP:UDP) 0.014855486327448944 prot_P36010 + ATP + UDP --> ADP + UTP 0.1552426239236641 r_0812 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + methanethiol + O-acetyl-L-homoserine --> acetate + H+ + L-methionine 0.0 -r_0813 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + hydrogen sulfide + O-acetyl-L-homoserine --> acetate + L-homocysteine 0.011924796613573426 +r_0813 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + hydrogen sulfide + O-acetyl-L-homoserine --> acetate + L-homocysteine 0.011924796613569849 r_0815_EXP_1 O-succinylhomoserine lyase (L-cysteine) 84.53345338034984 prot_Q12198 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 r_0815_EXP_2 O-succinylhomoserine lyase (L-cysteine) 0.170599173553719 prot_Q04533 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 r_0815_EXP_3 O-succinylhomoserine lyase (L-cysteine) 78.78148148148148 prot_P31373 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 @@ -994,16 +994,16 @@ r_0818 ornithine transacetylase 0.6359516214779373 prot_Q04728 + L-glutamate + N r_0819 ornithine transaminase 0.3585901027077497 prot_P07991 + 2-oxoglutarate + ornithine --> L-glutamate + L-glutamic 5-semialdehyde 0.0 r_0820_EXP_1 orotate phosphoribosyltransferase 5.27008547008547 prot_P13298 + diphosphate + orotidine 5'-(dihydrogen phosphate) --> orotate + PRPP 0.0 r_0820_EXP_2 orotate phosphoribosyltransferase 5.301495726495727 prot_P30402 + diphosphate + orotidine 5'-(dihydrogen phosphate) --> orotate + PRPP 0.0 -r_0820_REV_EXP_1 orotate phosphoribosyltransferase (reversible) 0.0019386279318367604 prot_P13298 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.01072683361457144 +r_0820_REV_EXP_1 orotate phosphoribosyltransferase (reversible) 0.0019386279318367604 prot_P13298 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.010726833614579986 r_0820_REV_EXP_2 orotate phosphoribosyltransferase (reversible) 0.001950182355530403 prot_P30402 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.0 -r_0821 orotidine-5'-phosphate decarboxylase 0.014249512670565302 prot_P03962 + H+ + orotidine 5'-(dihydrogen phosphate) --> carbon dioxide + UMP 0.01072683361457144 -r_0831_EXP_1 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.04684031538764905 prot_P09624 + 0.043736418169126635 prot_P19262 + 0.011871821465312496 prot_P19955 + 0.09922757869641279 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 0.7475000981339569 +r_0821 orotidine-5'-phosphate decarboxylase 0.014249512670565302 prot_P03962 + H+ + orotidine 5'-(dihydrogen phosphate) --> carbon dioxide + UMP 0.010726833614579986 +r_0831_EXP_1 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.04684031538764905 prot_P09624 + 0.043736418169126635 prot_P19262 + 0.011871821465312496 prot_P19955 + 0.09922757869641279 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 0.7475975783814619 r_0831_EXP_2 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 0.0 -r_0832_EXP_1 oxoglutarate dehydrogenase (lipoamide) 0.023116760828625234 prot_P09624 + 0.021584916966272898 prot_P19262 + 0.005859013867488444 prot_P19955 + 0.048971066598185245 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 0.7475000981339569 +r_0832_EXP_1 oxoglutarate dehydrogenase (lipoamide) 0.023116760828625234 prot_P09624 + 0.021584916966272898 prot_P19262 + 0.005859013867488444 prot_P19955 + 0.048971066598185245 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 0.7475975783814619 r_0832_EXP_2 oxoglutarate dehydrogenase (lipoamide) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 0.0 -r_0841 pantetheine-phosphate adenylyltransferase 1.9636765345605238 prot_P53332 + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 1.9000000614987463e-05 -r_0842 pantothenate kinase 5.359407756813417 prot_Q04430 + (R)-pantothenate + ATP --> (R)-4'-phosphopantothenic acid + ADP + H+ 1.9000000614987463e-05 -r_0843 pantothenate synthase 0.07626262626262627 prot_P40459 + (R)-pantoate + ATP + beta-alanine --> (R)-pantothenate + AMP + diphosphate + H+ 1.9000000614987463e-05 +r_0841 pantetheine-phosphate adenylyltransferase 1.9636765345605238 prot_P53332 + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 1.9000000611411882e-05 +r_0842 pantothenate kinase 5.359407756813417 prot_Q04430 + (R)-pantothenate + ATP --> (R)-4'-phosphopantothenic acid + ADP + H+ 1.9000000611411882e-05 +r_0843 pantothenate synthase 0.07626262626262627 prot_P40459 + (R)-pantoate + ATP + beta-alanine --> (R)-pantothenate + AMP + diphosphate + H+ 1.9000000611411882e-05 r_0844 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + decanoyl-CoA + H2O --> coenzyme A + decanoate + H+ 0.0 r_0845 peroxisomal acyl-CoA thioesterase 1.1039815728858178 prot_P41903 + H2O + lauroyl-CoA --> coenzyme A + H+ + laurate 0.0 r_0847 peroxisomal acyl-CoA thioesterase 302.2522522522523 prot_P41903 + H2O + palmitoyl-CoA --> coenzyme A + H+ + palmitate 0.0 @@ -1011,32 +1011,32 @@ r_0848 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + r_0849 peroxisomal acyl-CoA thioesterase 588.5964912280702 prot_P41903 + H2O + stearoyl-CoA --> coenzyme A + H+ + stearate 0.0 r_0850 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + octanoyl-CoA --> coenzyme A + H+ + octanoate 0.0 r_0851 phenylalanine transaminase 1.8801204819277106 prot_P53090 + 2-oxoglutarate + L-phenylalanine --> keto-phenylpyruvate + L-glutamate 0.0 -r_0851_REV phenylalanine transaminase (reversible) 0.550322030209992 prot_P53090 + keto-phenylpyruvate + L-glutamate --> 2-oxoglutarate + L-phenylalanine 0.06314882496141402 +r_0851_REV phenylalanine transaminase (reversible) 0.550322030209992 prot_P53090 + keto-phenylpyruvate + L-glutamate --> 2-oxoglutarate + L-phenylalanine 0.06314882496141398 r_0852 phenylalanyl-tRNA synthetase 0.06206467661691542 prot_P15624 + 0.05298599594619495 prot_P15625 + ATP + L-phenylalanine + tRNA(Phe) --> AMP + diphosphate + Phe-tRNA(Phe) 0.016679595802671702 r_0853 phenylalanyl-tRNA synthetase 0.025257508752533627 prot_P08425 + ATP + L-phenylalanine + tRNA(Phe) --> AMP + diphosphate + Phe-tRNA(Phe) 0.0 r_0854 phenylpyruvate decarboxylase 0.9914444444444445 prot_Q06408 + H+ + keto-phenylpyruvate --> carbon dioxide + phenylacetaldehyde 0.0 -r_0855 phopshoribosylaminoimidazole synthetase 3.4153968253968254 prot_P07244 + 5'-phosphoribosyl-N-formylglycineamidine + ATP --> 5'-phosphoribosyl-5-aminoimidazole + ADP + H+ + phosphate 0.010240426385265499 +r_0855 phopshoribosylaminoimidazole synthetase 3.4153968253968254 prot_P07244 + 5'-phosphoribosyl-N-formylglycineamidine + ATP --> 5'-phosphoribosyl-5-aminoimidazole + ADP + H+ + phosphate 0.01024042638525807 r_0882 phosphoacetylglucosamine mutase 0.4264366394591475 prot_P38628 + N-acetyl-D-glucosamine 6-phosphate --> N-acetyl-alpha-D-glucosamine 1-phosphate 0.0023610000000000003 r_0882_REV phosphoacetylglucosamine mutase (reversible) 0.4264366394591475 prot_P38628 + N-acetyl-alpha-D-glucosamine 1-phosphate --> N-acetyl-D-glucosamine 6-phosphate 0.0 -r_0883_EXP_1 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8892063492063492 prot_P22803 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.01192491661357767 +r_0883_EXP_1 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8892063492063492 prot_P22803 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.011924916613574097 r_0883_EXP_2 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8916666666666667 prot_P22217 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.0 r_0884 phosphoenolpyruvate carboxykinase 0.27322132616487455 prot_P10963 + ATP + oxaloacetate --> ADP + carbon dioxide + phosphoenolpyruvate 0.0 r_0885 phosphoethanolamine cytidyltransferase 8.904106280193236 prot_P33412 + CTP + H+ + O-phosphoethanolamine --> CDP-ethanolamine + diphosphate 0.0 -r_0886 phosphofructokinase 0.06875388870533351 prot_P16861 + 0.06661937879572642 prot_P16862 + ATP + D-fructose 6-phosphate --> ADP + D-fructose 1,6-bisphosphate + H+ 0.830900089675868 +r_0886 phosphofructokinase 0.06875388870533351 prot_P16861 + 0.06661937879572642 prot_P16862 + ATP + D-fructose 6-phosphate --> ADP + D-fructose 1,6-bisphosphate + H+ 0.8309307105009115 r_0888_EXP_1 phosphoglucomutase 0.08151033591731266 prot_P37012 + D-glucose 6-phosphate --> D-glucose 1-phosphate 0.147954 r_0888_EXP_2 phosphoglucomutase 0.08154005167958657 prot_P33401 + D-glucose 6-phosphate --> D-glucose 1-phosphate 0.0 r_0888_REV_EXP_1 phosphoglucomutase (reversible) 0.08151033591731266 prot_P37012 + D-glucose 1-phosphate --> D-glucose 6-phosphate 0.0 r_0888_REV_EXP_2 phosphoglucomutase (reversible) 0.08154005167958657 prot_P33401 + D-glucose 1-phosphate --> D-glucose 6-phosphate 0.0 r_0889_EXP_1 phosphogluconate dehydrogenase 0.41150030525030523 prot_P53319 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.0 -r_0889_EXP_2 phosphogluconate dehydrogenase 0.40860042735042734 prot_P38720 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.31375894768961987 +r_0889_EXP_2 phosphogluconate dehydrogenase 0.40860042735042734 prot_P38720 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.31367026422156963 r_0890 phosphoglucosamine mutase 0.4264366394591475 prot_P38628 + alpha-D-glucosamine 1-phosphate --> alpha-D-glucosamine 6-phosphate 0.0 r_0890_REV phosphoglucosamine mutase (reversible) 0.4264366394591475 prot_P38628 + alpha-D-glucosamine 6-phosphate --> alpha-D-glucosamine 1-phosphate 0.0 r_0891_EXP_1 phosphoglycerate dehydrogenase 0.0036935786435786434 prot_P40054 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.0 -r_0891_EXP_2 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.0881015539961885 -r_0892 phosphoglycerate kinase 0.02315487650870546 prot_P00560 + 1,3-bisphospho-D-glycerate + ADP --> 3-phosphonato-D-glycerate(3-) + ATP 1.7300502454646378 +r_0891_EXP_2 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.08804630873990749 +r_0892 phosphoglycerate kinase 0.02315487650870546 prot_P00560 + 1,3-bisphospho-D-glycerate + ADP --> 3-phosphonato-D-glycerate(3-) + ATP 1.7300924804562703 r_0892_REV phosphoglycerate kinase (reversible) 0.02315487650870546 prot_P00560 + 3-phosphonato-D-glycerate(3-) + ATP --> 1,3-bisphospho-D-glycerate + ADP 0.0 r_0893_EXP_1 phosphoglycerate mutase 1.1738045797601886 prot_Q12040 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 0.0 -r_0893_EXP_2 phosphoglycerate mutase 0.013314525462962964 prot_P00950 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 1.6419486914684494 +r_0893_EXP_2 phosphoglycerate mutase 0.013314525462962964 prot_P00950 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 1.6420461717163628 r_0893_REV_EXP_1 phosphoglycerate mutase (reversible) 2.640272344101795 prot_Q12040 + 2-phospho-D-glyceric acid --> 3-phosphonato-D-glycerate(3-) 0.0 r_0893_REV_EXP_2 phosphoglycerate mutase (reversible) 0.013314525462962964 prot_P00950 + 2-phospho-D-glyceric acid --> 3-phosphonato-D-glycerate(3-) 0.0 r_0902 phosphomannomutase 1.8347853535353533 prot_P07283 + D-mannose 1-phosphate --> D-mannose 6-phosphate 0.0 @@ -1044,33 +1044,33 @@ r_0902_REV phosphomannomutase (reversible) 0.40001070189485594 prot_P07283 + D-m r_0903_EXP_1 phosphomethylpyrimidine kinase 39.57945736434109 prot_Q08224 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 1.7870618916851721e-07 r_0903_EXP_2 phosphomethylpyrimidine kinase 39.62144702842377 prot_Q08975 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 0.0 r_0903_EXP_3 phosphomethylpyrimidine kinase 695.1822835935426 prot_Q06490 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP -5.870618492401421e-08 -r_0904 phosphomevalonate kinase 4.122140522875817 prot_P24521 + (R)-5-phosphomevalonic acid + ATP --> (R)-5-diphosphomevalonic acid + ADP 0.02212645946904527 -r_0905 phosphopantothenate-cysteine ligase 4.010249042145594 prot_P40506 + (R)-4'-phosphopantothenic acid + CTP + L-cysteine --> CMP + diphosphate + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine 1.9000000614987463e-05 -r_0906 phosphopantothenoylcysteine decarboxylase 5.98448275862069 prot_P36024 + 6.248850574712644 prot_P36076 + 7.054501915708812 prot_Q08438 + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine --> carbon dioxide + pantetheine 4'-phosphate 1.9000000614987463e-05 +r_0904 phosphomevalonate kinase 4.122140522875817 prot_P24521 + (R)-5-phosphomevalonic acid + ATP --> (R)-5-diphosphomevalonic acid + ADP 0.022126459469172997 +r_0905 phosphopantothenate-cysteine ligase 4.010249042145594 prot_P40506 + (R)-4'-phosphopantothenic acid + CTP + L-cysteine --> CMP + diphosphate + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine 1.9000000611411882e-05 +r_0906 phosphopantothenoylcysteine decarboxylase 5.98448275862069 prot_P36024 + 6.248850574712644 prot_P36076 + 7.054501915708812 prot_Q08438 + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine --> carbon dioxide + pantetheine 4'-phosphate 1.9000000611411882e-05 r_0907_EXP_1 phosphopentomutase 0.08154005167958657 prot_P33401 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_EXP_2 phosphopentomutase 0.08151033591731266 prot_P37012 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_EXP_3 phosphopentomutase 0.10671021021021021 prot_Q03262 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_REV_EXP_1 phosphopentomutase (reversible) 0.08154005167958657 prot_P33401 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0 -r_0907_REV_EXP_2 phosphopentomutase (reversible) 0.08151033591731266 prot_P37012 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 1.9000000614987463e-05 +r_0907_REV_EXP_2 phosphopentomutase (reversible) 0.08151033591731266 prot_P37012 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 1.9000000611411882e-05 r_0907_REV_EXP_3 phosphopentomutase (reversible) 0.10671021021021021 prot_Q03262 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0 -r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.17755272474518155 prot_P27616 + ATP + L-aspartate + phosphoribosyl-carboxy-aminoimidazole --> 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + 2.0 H+ + phosphate 0.010240306385261255 +r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.17755272474518155 prot_P27616 + ATP + L-aspartate + phosphoribosyl-carboxy-aminoimidazole --> 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + 2.0 H+ + phosphate 0.010240306385253826 r_0909 phosphoribosyl-AMP cyclohydrolase 0.00852140040022537 prot_P00815 + 1-(5-phosphoribosyl)-5'-AMP + H2O --> 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide 0.008356708763266002 r_0910 phosphoribosyl-ATP pyrophosphatase 6.601766492974471 prot_P00815 + 5-phosphoribosyl-ATP + H2O --> 1-(5-phosphoribosyl)-5'-AMP + diphosphate + H+ 0.008356708763266002 -r_0911 phosphoribosylaminoimidazole-carboxylase 0.2248881673881674 prot_P21264 + 5'-phosphoribosyl-5-aminoimidazole + carbon dioxide --> H+ + phosphoribosyl-carboxy-aminoimidazole 0.010240306385261255 +r_0911 phosphoribosylaminoimidazole-carboxylase 0.2248881673881674 prot_P21264 + 5'-phosphoribosyl-5-aminoimidazole + carbon dioxide --> H+ + phosphoribosyl-carboxy-aminoimidazole 0.010240306385253826 r_0912_EXP_1 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.10859173126615 prot_P54113 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.0 -r_0912_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.1079780361757106 prot_P38009 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.018597015148527254 +r_0912_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.1079780361757106 prot_P38009 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.01859701514851983 r_0912_REV_EXP_1 phosphoribosylaminoimidazolecarboxamide formyltransferase (reversible) 2.10859173126615 prot_P54113 + phosphoribosyl-formamido-carboxamide + THF --> 10-formyl-THF + AICAR 0.0 r_0912_REV_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase (reversible) 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide + THF --> 10-formyl-THF + AICAR 0.0 -r_0913 phosphoribosylanthranilate isomerase 0.09719806763285024 prot_P00912 + N-(5-phospho-beta-D-ribosyl)anthranilate --> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 0.004463981443244593 -r_0914 phosphoribosylglycinamidine synthetase 3.4153968253968254 prot_P07244 + 5-phosphoribosylamine + ATP + L-glycine --> 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate 0.010240426385265499 -r_0915 phosphoribosylpyrophosphate amidotransferase 0.28336830535571544 prot_P04046 + H2O + L-glutamine + PRPP --> 5-phosphoribosylamine + diphosphate + L-glutamate 0.010240426385265499 -r_0916_EXP_1 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11565202927478377 prot_P38620 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.03439507020375056 +r_0913 phosphoribosylanthranilate isomerase 0.09719806763285024 prot_P00912 + N-(5-phospho-beta-D-ribosyl)anthranilate --> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 0.004463981443244646 +r_0914 phosphoribosylglycinamidine synthetase 3.4153968253968254 prot_P07244 + 5-phosphoribosylamine + ATP + L-glycine --> 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate 0.01024042638525807 +r_0915 phosphoribosylpyrophosphate amidotransferase 0.28336830535571544 prot_P04046 + H2O + L-glutamine + PRPP --> 5-phosphoribosylamine + diphosphate + L-glutamate 0.01024042638525807 +r_0916_EXP_1 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11565202927478377 prot_P38620 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.03439507020375178 r_0916_EXP_2 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11684630738522954 prot_P38689 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_3 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11882900864936793 prot_P38063 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_4 phosphoribosylpyrophosphate synthetase 0.11565202927478377 prot_P38620 + 0.17799401197604792 prot_Q12265 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_5 phosphoribosylpyrophosphate synthetase 0.11882900864936793 prot_P38063 + 0.17799401197604792 prot_Q12265 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 -r_0917 phosphoserine phosphatase (L-serine) 0.006309392061384094 prot_P42941 + 3-phospho-serine + H2O --> L-serine + phosphate 0.0881015539961885 -r_0918 phosphoserine transaminase 4.103165485515034 prot_P33330 + 3-phospho-hydroxypyruvate + L-glutamate --> 2-oxoglutarate + 3-phospho-serine 0.0881015539961885 +r_0917 phosphoserine phosphatase (L-serine) 0.006309392061384094 prot_P42941 + 3-phospho-serine + H2O --> L-serine + phosphate 0.08804630873990749 +r_0918 phosphoserine transaminase 4.103165485515034 prot_P33330 + 3-phospho-hydroxypyruvate + L-glutamate --> 2-oxoglutarate + 3-phospho-serine 0.08804630873990749 r_0919 phytoceramidase 13.387690165065315 prot_P38298 + lignoceric acid + phytosphingosine --> ceramide-2 (C24) + H2O 0.0 r_0920 phytoceramidase 107.0999354737445 prot_P21595 + cerotic acid + phytosphingosine --> ceramide-2 (C26) + H2O 0.0 r_0921 Phytosphingosine phosphate lyase 82.78535353535354 prot_Q05567 + phytosphingosine 1-phosphate --> 2-hydroxyhexadecanal + O-phosphoethanolamine 0.0 @@ -1078,8 +1078,8 @@ r_0922 phytosphingosine synthesis 30.50853889148629 prot_P38992 + H+ + NADPH + o r_0929 polyamine oxidase 0.4117236467236467 prot_P50264 + H2O + N(1)-acetylspermidine + oxygen --> 3-aminopropanal + hydrogen peroxide + N-acetylputrescine 0.0 r_0935 porphobilinogen synthase 1.9935529153386848 prot_P05373 + 2.0 5-aminolevulinate --> H+ + 2.0 H2O + porphobilinogen 0.0 r_0936 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + N(1)-acetylspermine + oxygen --> 3-aminopropanal + hydrogen peroxide + N(1)-acetylspermidine 0.0 -r_0937 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + oxygen + spermine --> 3-aminopropanal + hydrogen peroxide + spermidine 1.9000000614987463e-05 -r_0938 prephenate dehydratase 0.012934651669576752 prot_P32452 + H+ + prephenate --> carbon dioxide + H2O + keto-phenylpyruvate 0.016679595802671702 +r_0937 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + oxygen + spermine --> 3-aminopropanal + hydrogen peroxide + spermidine 1.9000000611411882e-05 +r_0938 prephenate dehydratase 0.012934651669576752 prot_P32452 + H+ + prephenate --> carbon dioxide + H2O + keto-phenylpyruvate 0.016679595802671705 r_0939 prephenate dehydrogenase (NADP) 0.537843261512463 prot_P20049 + NAD + prephenate --> 3-(4-hydroxyphenyl)pyruvate + carbon dioxide + NADH 0.012302566079285501 r_0940 proline oxidase (NAD) 0.44171641791044775 prot_P09368 + FAD + L-proline --> 1-pyrroline-5-carboxylate + FADH2 0.06753022171843157 r_0941 prolyl-tRNA synthetase 3.83859126984127 prot_P38708 + ATP + L-proline + tRNA(Pro) --> AMP + diphosphate + Pro-tRNA(Pro) 0.0179821149401597 @@ -1097,22 +1097,22 @@ r_0955 pyridoxine 5'-phosphate oxidase 10.677777777777777 prot_P38075 + oxygen + r_0956 pyridoxine oxidase 10.677777777777777 prot_P38075 + oxygen + pyridoxine --> hydrogen peroxide + pyridoxal 0.0 r_0957 pyrroline-5-carboxylate reductase 0.0020925 prot_P32263 + 1-pyrroline-5-carboxylate + 2.0 H+ + NADPH --> L-proline + NADP(+) 0.08551233665859126 r_0958_EXP_1 pyruvate carboxylase 0.602625 prot_P32327 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.0 -r_0958_EXP_2 pyruvate carboxylase 0.6023101851851852 prot_P11154 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.24368621257252093 +r_0958_EXP_2 pyruvate carboxylase 0.6023101851851852 prot_P11154 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.243686212572512 r_0959_EXP_1 pyruvate decarboxylase 0.27589605734767025 prot_P26263 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.0 -r_0959_EXP_2 pyruvate decarboxylase 0.08176022088979121 prot_P06169 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.1371175061288993 +r_0959_EXP_2 pyruvate decarboxylase 0.08176022088979121 prot_P06169 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.13711750612929502 r_0959_EXP_3 pyruvate decarboxylase 0.27738351254480287 prot_P16467 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.0 r_0960_EXP_1 pyruvate decarboxylase (acetoin-forming) 0.27589605734767025 prot_P26263 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 r_0960_EXP_2 pyruvate decarboxylase (acetoin-forming) 0.11780651340996169 prot_P06169 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 r_0960_EXP_3 pyruvate decarboxylase (acetoin-forming) 0.27738351254480287 prot_P16467 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 -r_0961 pyruvate dehydrogenase 0.23664570803230708 prot_P09624 + 1.1352071189426114 prot_P12695 + 0.4061052415234663 prot_P16387 + 0.19875435304131667 prot_P16451 + 0.35099452655160257 prot_P32473 + coenzyme A + NAD + pyruvate --> acetyl-CoA + carbon dioxide + NADH 1.019968655889245 -r_0962_EXP_1 pyruvate kinase 0.06530771072796934 prot_P00549 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 1.5750437248175366 +r_0961 pyruvate dehydrogenase 0.23664570803230708 prot_P09624 + 1.1352071189426114 prot_P12695 + 0.4061052415234663 prot_P16387 + 0.19875435304131667 prot_P16451 + 0.35099452655160257 prot_P32473 + coenzyme A + NAD + pyruvate --> acetyl-CoA + carbon dioxide + NADH 1.0200661361367604 +r_0962_EXP_1 pyruvate kinase 0.06530771072796934 prot_P00549 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 1.5751412050654499 r_0962_EXP_2 pyruvate kinase 0.06608596743295019 prot_P52489 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 0.0 r_0963 quinone oxidoreductase 0.2834173315594083 prot_O13525 + 0.266570923780901 prot_P27680 + 0.191209663200305 prot_P41735 + 0.2544937516539746 prot_P49017 + 0.39274288726487816 prot_P53318 + 0.21981040253855474 prot_Q05779 + 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + NADH + oxygen --> 2-hexaprenyl-5-hydroxy-6-methoxy-3-methyl-1,4-benzoquinone + H2O + NAD 0.0 r_0964 reduced glutathione via ABC system 161.4141633681904 prot_P39109 + ATP + glutathione + H2O --> ADP + glutathione + H+ + phosphate 0.0 r_0965 riboflavin kinase 68.15833333333333 prot_Q03778 + ATP + riboflavin --> ADP + FMN + H+ 0.0 r_0966 riboflavin kinase 68.15833333333333 prot_Q03778 + ATP + riboflavin --> ADP + FMN + H+ 0.0 -r_0967 riboflavin synthase 1.4057441999969114 prot_P50861 + 2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil --> 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ + 2.0 H2O + phosphate 0.00019999999421999037 -r_0968 riboflavin synthase 54.506866416978774 prot_P38145 + 2.0 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ --> 5-amino-6-(D-ribitylamino)uracil + riboflavin 9.999999710999519e-05 +r_0967 riboflavin synthase 1.4057441999969114 prot_P50861 + 2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil --> 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ + 2.0 H2O + phosphate 0.00019999999421997937 +r_0968 riboflavin synthase 54.506866416978774 prot_P38145 + 2.0 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ --> 5-amino-6-(D-ribitylamino)uracil + riboflavin 9.999999710998968e-05 r_0969 ribokinase 0.214529735759604 prot_P25332 + ATP + D-ribose --> ADP + H+ + ribose-5-phosphate 0.0 r_0970 ribonucleoside-triphosphate reductase (ATP) 1.6386358549460274 prot_P22803 + ATP + H+ + TRX1 --> dATP + H2O + TRX1 disulphide 0.0 r_0971 ribonucleoside-triphosphate reductase (CTP) 3.573997388312029 prot_P22803 + CTP + H+ + TRX1 --> dCTP + H2O + TRX1 disulphide 0.0 @@ -1142,10 +1142,10 @@ r_0979_EXP_1 ribonucleotide reductase 2.143863049095607 prot_P21524 + GDP + H+ + r_0979_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 r_0979_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 r_0979_EXP_4 ribonucleotide reductase 0.9936907838070629 prot_P09938 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 -r_0982 ribose-5-phosphate isomerase 0.5468480156600358 prot_Q12189 + D-ribulose 5-phosphate --> ribose-5-phosphate 0.13861319047652912 +r_0982 ribose-5-phosphate isomerase 0.5468480156600358 prot_Q12189 + D-ribulose 5-phosphate --> ribose-5-phosphate 0.13858362932051083 r_0982_REV ribose-5-phosphate isomerase (reversible) 0.817650462962963 prot_Q12189 + ribose-5-phosphate --> D-ribulose 5-phosphate 0.0 r_0983 ribosylnicotinamide kinase 4.5245098039215685 prot_P53915 + ATP + nicotinamide riboside --> ADP + H+ + NMN 0.0 -r_0984 ribulose 5-phosphate 3-epimerase 0.06355115026921195 prot_P46969 + D-ribulose 5-phosphate --> D-xylulose 5-phosphate 0.17494575721887076 +r_0984 ribulose 5-phosphate 3-epimerase 0.06355115026921195 prot_P46969 + D-ribulose 5-phosphate --> D-xylulose 5-phosphate 0.17488663490683884 r_0984_REV ribulose 5-phosphate 3-epimerase (reversible) 0.06355115026921195 prot_P46969 + D-xylulose 5-phosphate --> D-ribulose 5-phosphate 0.0 r_0985 S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase 0.55303275478674 prot_O13525 + 0.5201603286342985 prot_P27680 + 0.37310776373372107 prot_P41735 + 0.49659412068703435 prot_P49017 + 0.7663599105669565 prot_P53318 + 0.42891643844723004 prot_Q05779 + 3-hexaprenyl-4,5-dihydroxybenzoic acid + S-adenosyl-L-methionine --> 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid + H+ + S-adenosyl-L-homocysteine 0.0 r_0986 S-adenosyl-methionine delta-24-sterol-c-methyltransferase 1096.7424242424245 prot_P25087 + S-adenosyl-L-methionine + zymosterol --> fecosterol + H+ + S-adenosyl-L-homocysteine 0.0 @@ -1158,14 +1158,14 @@ r_0992 serine O-acetyltransferase 17.435821109618253 prot_P07347 + 62.4747269081 r_0993 serine palmitotransferase 11.220598845598845 prot_P25045 + 12.829184704184705 prot_P32368 + 11.383658008658008 prot_P40970 + 4.553571428571429 prot_P53224 + 4.483225108225108 prot_Q06144 + 1.727813852813853 prot_Q3E790 + H+ + L-serine + palmitoyl-CoA --> 3-ketosphinganine + carbon dioxide + coenzyme A 0.0 r_0995_EXP_1 seryl-tRNA synthetase 3.797008547008547 prot_P07284 + ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + Ser-tRNA(Ser) 0.02657315433982251 r_0995_EXP_2 seryl-tRNA synthetase 3.589031339031339 prot_P38705 + ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + Ser-tRNA(Ser) 0.0011994115584826935 -r_0996 shikimate dehydrogenase 0.12478934590117109 prot_P08566 + 3-dehydroshikimate + H+ + NADPH --> NADP(+) + shikimate 0.03345248332545636 -r_0997 shikimate kinase 0.1645527306967985 prot_P08566 + ATP + shikimate --> 3-phosphoshikimic acid + ADP + H+ 0.03345248332545636 +r_0996 shikimate dehydrogenase 0.12478934590117109 prot_P08566 + 3-dehydroshikimate + H+ + NADPH --> NADP(+) + shikimate 0.03345248332545642 +r_0997 shikimate kinase 0.1645527306967985 prot_P08566 + ATP + shikimate --> 3-phosphoshikimic acid + ADP + H+ 0.03345248332545642 r_0998 sirohydrochlorin dehydrogenase 147.7685185185185 prot_P15807 + NAD + precorrin-2 --> 2.0 H+ + NADH + sirohydrochlorin 0.0 r_0999 sirohydrochlorin ferrochetalase 147.7685185185185 prot_P15807 + iron(2+) + sirohydrochlorin --> 2.0 H+ + siroheme 0.0 r_1000 fumarate reductase (FMN) 0.9170995670995671 prot_P32614 + FMNH2 + fumarate --> FMN + H+ + succinate 0.0 r_1000_REV fumarate reductase (FMN) (reversible) 0.9170995670995671 prot_P32614 + FMN + H+ + succinate --> FMNH2 + fumarate 0.0 r_1001 spermidine synthase 0.4077826725403818 prot_Q12074 + putrescine + S-adenosylmethioninamine --> 5'-S-methyl-5'-thioadenosine + H+ + spermidine 0.0 -r_1002 spermine synthase 0.29592881944444444 prot_Q12455 + S-adenosylmethioninamine + spermidine --> 5'-S-methyl-5'-thioadenosine + H+ + spermine 1.9000000614987463e-05 +r_1002 spermine synthase 0.29592881944444444 prot_Q12455 + S-adenosylmethioninamine + spermidine --> 5'-S-methyl-5'-thioadenosine + H+ + spermine 1.9000000611411882e-05 r_1003 sphinganine phosphate lyase 1214.1851851851852 prot_Q05567 + sphinganine 1-phosphate --> hexadecanal + O-phosphoethanolamine 0.0 r_1004_EXP_1 sphingoid base-phosphate phosphatase (phytosphingosine 1-phosphate) 1940.4587619197007 prot_P47013 + H2O + phytosphingosine 1-phosphate --> phosphate + phytosphingosine 0.0 r_1004_EXP_2 sphingoid base-phosphate phosphatase (phytosphingosine 1-phosphate) 8490.20229957777 prot_P23501 + H2O + phytosphingosine 1-phosphate --> phosphate + phytosphingosine 0.0 @@ -1180,20 +1180,20 @@ r_1008_REV spontaneous cis-aconitate(3-) to trans-aconitate (reversible) 1.13290 r_1009 spontaneous cis-aconitate(3-) to trans-aconitate 1.1329040404040405 prot_standard + cis-aconitate --> trans-aconitate 0.0 r_1009_REV spontaneous cis-aconitate(3-) to trans-aconitate (reversible) 1.1329040404040405 prot_standard + trans-aconitate --> cis-aconitate 0.0 r_1010 squalene epoxidase (NAD) 201.483918128655 prot_P32476 + H+ + NADH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NAD 0.0 -r_1011 squalene epoxidase (NADP) 161.16753104520652 prot_P32476 + H+ + NADPH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NADP(+) 0.003687743244840878 -r_1012 squalene synthase 8.707070707070708 prot_P29704 + 2.0 farnesyl diphosphate + H+ + NADPH --> 2.0 diphosphate + NADP(+) + squalene 0.003687743244840878 +r_1011 squalene epoxidase (NADP) 161.16753104520652 prot_P32476 + H+ + NADPH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NADP(+) 0.003687743244862164 +r_1012 squalene synthase 8.707070707070708 prot_P29704 + 2.0 farnesyl diphosphate + H+ + NADPH --> 2.0 diphosphate + NADP(+) + squalene 0.003687743244862164 r_1021_EXP_1 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07412606837606837 prot_P47052 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.0 r_1021_EXP_2 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07503098290598291 prot_Q00711 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.0 -r_1021_EXP_3 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.07412606837606837 prot_P47052 + 0.019905982905982906 prot_Q06236 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.8257571534669599 +r_1021_EXP_3 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.07412606837606837 prot_P47052 + 0.019905982905982906 prot_Q06236 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.8258546337144734 r_1021_REV_EXP_1 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.022498888888888888 prot_P37298 + 0.07709111111111111 prot_P47052 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 r_1021_REV_EXP_2 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.022498888888888888 prot_P37298 + 0.07803222222222223 prot_Q00711 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 r_1021_REV_EXP_3 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.07709111111111111 prot_P47052 + 0.020702222222222223 prot_Q06236 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 -r_1022 succinate-CoA ligase (ADP-forming) 0.06481619679380873 prot_P53312 + 0.048413488114980655 prot_P53598 + ADP + phosphate + succinyl-CoA --> ATP + coenzyme A + succinate 0.7475000981343337 +r_1022 succinate-CoA ligase (ADP-forming) 0.06481619679380873 prot_P53312 + 0.048413488114980655 prot_P53598 + ADP + phosphate + succinyl-CoA --> ATP + coenzyme A + succinate 0.7475975783814619 r_1023 succinate-semialdehyde dehydrogenase (NADP) 0.6660398230088496 prot_P38067 + H2O + NADP(+) + succinic semialdehyde --> 2.0 H+ + NADPH + succinate 0.0 r_1024 sucrose hydrolyzing enzyme 0.004910835762876579 prot_P00724 + H2O + sucrose --> D-fructose + D-glucose 0.0 -r_1025 sulfate adenylyltransferase 0.6571607468123861 prot_P08536 + ATP + H+ + sulphate --> 5'-adenylyl sulfate + diphosphate 0.01192491661357767 +r_1025 sulfate adenylyltransferase 0.6571607468123861 prot_P08536 + ATP + H+ + sulphate --> 5'-adenylyl sulfate + diphosphate 0.011924916613574097 r_1026 sulfate adenylyltransferase (ADP) 0.10559317129629629 prot_P16550 + 5'-adenylyl sulfate + phosphate --> ADP + H+ + sulphate 0.0 -r_1027 sulfite reductase (NADPH2) 0.4089351851851852 prot_P39692 + 0.574141737891738 prot_P47169 + 4.0 H+ + 3.0 NADPH + sulphite --> 3.0 H2O + hydrogen sulfide + 3.0 NADP(+) 0.01192491661357767 +r_1027 sulfite reductase (NADPH2) 0.4089351851851852 prot_P39692 + 0.574141737891738 prot_P47169 + 4.0 H+ + 3.0 NADPH + sulphite --> 3.0 H2O + hydrogen sulfide + 3.0 NADP(+) 0.011924916613574097 r_1028 taurcholate via ABC system 571.7858889359086 prot_P32386 + ATP + H2O + taurocholate --> ADP + H+ + phosphate + taurocholate 0.0 r_1029 taurine dioxygenase 0.6971220085126848 prot_Q12358 + 2-oxoglutarate + oxygen + taurine --> aminoacetaldehyde + carbon dioxide + H+ + succinate + sulphite 0.0 r_1030 tetrahydrofolate aminomethyltransferase 0.12487609595740357 prot_P09624 + 0.0434511474046933 prot_P39726 + 0.10281642494222884 prot_P48015 + 0.2646212564047546 prot_P49095 + 5,10-methenyl-THF + H2O --> 5-formyltetrahydrofolic acid + H+ 0.0 @@ -1210,7 +1210,7 @@ r_1037_EXP_1 thioredoxin 0.16380116959064328 prot_P22803 + 0.3526315789473684 pr r_1037_EXP_2 thioredoxin 0.1642543859649123 prot_P22217 + 0.3526315789473684 prot_P40553 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_1038_EXP_1 thioredoxin reductase (NADPH) 0.09346012679346014 prot_P22803 + 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1038_EXP_2 thioredoxin reductase (NADPH) 0.09371871871871873 prot_P22217 + 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 -r_1038_EXP_3 thioredoxin reductase (NADPH) 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.013124916624008482 +r_1038_EXP_3 thioredoxin reductase (NADPH) 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.013124916624004909 r_1039_EXP_1 thioredoxin reductase (NADPH) 0.12038705372038706 prot_P25372 + 0.3093677010343677 prot_P38816 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1039_EXP_2 thioredoxin reductase (NADPH) 0.004454320987654321 prot_P25372 + 0.016494135802469136 prot_P41921 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1040 threonine aldolase 0.2765826873385013 prot_P37303 + L-threonine --> acetaldehyde + L-glycine 0.0 @@ -1221,22 +1221,22 @@ r_1045 thymidylate synthase 0.20281828703703703 prot_P06785 + 5,10-methylenetetr r_1046 trans-aconitate 3-methyltransferase 147.17240726195595 prot_P32643 + S-adenosyl-L-methionine + trans-aconitate --> (2E)-3-(methoxycarbonyl)pent-2-enedioic acid + S-adenosyl-L-homocysteine 0.0 r_1047 trans-pentaprenyltranstransferase 1.43565817535086 prot_P18900 + isopentenyl diphosphate + pentaprenyl diphosphate --> diphosphate + hexaprenyl diphosphate 0.0 r_1048_EXP_1 transaldolase 0.796025641025641 prot_P53228 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.0 -r_1048_EXP_2 transaldolase 0.13717037037037036 prot_P15019 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.10419912027216356 +r_1048_EXP_2 transaldolase 0.13717037037037036 prot_P15019 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.10416955911614763 r_1048_REV_EXP_1 transaldolase (reversible) 0.4518922852983988 prot_P53228 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 r_1048_REV_EXP_2 transaldolase (reversible) 0.13717037037037036 prot_P15019 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 r_1049_EXP_1 transketolase 1 0.30204911433172305 prot_P33315 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 -r_1049_EXP_2 transketolase 1 0.2971256038647343 prot_P23254 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.10419912027216356 +r_1049_EXP_2 transketolase 1 0.2971256038647343 prot_P23254 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.10416955911614763 r_1049_REV_EXP_1 transketolase 1 (reversible) 0.30204911433172305 prot_P33315 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0 r_1049_REV_EXP_2 transketolase 1 (reversible) 0.2971256038647343 prot_P23254 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0 r_1050_EXP_1 transketolase 2 0.30204911433172305 prot_P33315 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.0 -r_1050_EXP_2 transketolase 2 0.2971256038647343 prot_P23254 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.0707466369467072 +r_1050_EXP_2 transketolase 2 0.2971256038647343 prot_P23254 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.07071707579069121 r_1050_REV_EXP_1 transketolase 2 (reversible) 0.30204911433172305 prot_P33315 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.0 r_1050_REV_EXP_2 transketolase 2 (reversible) 0.2971256038647343 prot_P23254 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.0 r_1051_EXP_1 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5532575757575757 prot_P38427 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.0 r_1051_EXP_2 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5004419191919192 prot_P38426 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.013655 -r_1054 triose-phosphate isomerase 0.0008592271925605259 prot_P00942 + dihydroxyacetone phosphate --> glyceraldehyde 3-phosphate 0.8239395373988182 +r_1054 triose-phosphate isomerase 0.0008592271925605259 prot_P00942 + dihydroxyacetone phosphate --> glyceraldehyde 3-phosphate 0.8239807127214211 r_1054_REV triose-phosphate isomerase (reversible) 0.0008592271925605259 prot_P00942 + glyceraldehyde 3-phosphate --> dihydroxyacetone phosphate 0.0 -r_1055 tryptophan synthase (indoleglycerol phosphate) 0.43168564547057753 prot_P00931 + 1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> glyceraldehyde 3-phosphate + H2O + L-tryptophan 0.004463981443244593 +r_1055 tryptophan synthase (indoleglycerol phosphate) 0.43168564547057753 prot_P00931 + 1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> glyceraldehyde 3-phosphate + H2O + L-tryptophan 0.004463981443244646 r_1056 tryptophan transaminase 1.2484 prot_P53090 + 2-oxoglutarate + L-tryptophan --> indole-3-pyruvate + L-glutamate 0.0 r_1057 tryptophanyl-tRNA synthetase 0.5595238095238095 prot_Q12109 + ATP + L-tryptophan + tRNA(Trp) --> AMP + diphosphate + Trp-tRNA(Trp) 0.0038569814458458205 r_1058 tryptophanyl-tRNA synthetase 0.4876984126984127 prot_P04803 + ATP + L-tryptophan + tRNA(Trp) --> AMP + diphosphate + Trp-tRNA(Trp) 0.0 @@ -1252,8 +1252,8 @@ r_1070 UDPglucose 4-epimerase 0.532373366013072 prot_P04397 + UDP-D-glucose --> r_1070_REV UDPglucose 4-epimerase (reversible) 0.532373366013072 prot_P04397 + UDP-D-galactose --> UDP-D-glucose 0.0 r_1071 UDPglucose--hexose-1-phosphate uridylyltransferase 0.3270447530864197 prot_P08431 + alpha-D-galactose 1-phosphate + UDP-D-glucose --> D-glucose 1-phosphate + UDP-D-galactose 0.0 r_1071_REV UDPglucose--hexose-1-phosphate uridylyltransferase (reversible) 0.3270447530864197 prot_P08431 + D-glucose 1-phosphate + UDP-D-galactose --> alpha-D-galactose 1-phosphate + UDP-D-glucose 0.0 -r_1072 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.0 -r_1073 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.004927623923655561 +r_1072 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.004927623923664107 +r_1073 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.0 r_1074 uracil phosphoribosyltransferase 1.1199453551912568 prot_P18562 + PRPP + uracil --> diphosphate + UMP 0.0 r_1075 urea carboxylase 0.26596036263967954 prot_P32528 + ATP + bicarbonate + urea --> ADP + H+ + phosphate + urea-1-carboxylic acid 0.0 r_1076 ureidoglycolate hydrolase 335.29320987654324 prot_P32459 + 2.0 H+ + H2O + ureidoglycolic acid --> 2.0 ammonium + carbon dioxide + glyoxylate 0.0 @@ -1319,17 +1319,17 @@ r_1108_EXP_2 adenine transport 96.43325000488205 prot_P40039 + adenine + H+ --> r_1108_EXP_3 adenine transport 170.37838815188596 prot_Q12119 + adenine + H+ --> adenine + H+ 0.0 r_1109 adenosine transport 38.061322453849215 prot_P31381 + adenosine + H+ --> adenosine + H+ 0.0 r_1110_EXP_1 ADP/ATP transporter 0.06555300613384876 prot_P18239 + ADP + ATP --> ADP + ATP 0.0 -r_1110_EXP_2 ADP/ATP transporter 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 7.388387054168606 +r_1110_EXP_2 ADP/ATP transporter 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 7.389118409601448 r_1110_EXP_3 ADP/ATP transporter 0.045422922213833025 prot_P04710 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_1 ADP/ATP transporter (reversible) 0.06555300613384876 prot_P18239 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_2 ADP/ATP transporter (reversible) 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_3 ADP/ATP transporter (reversible) 0.045422922213833025 prot_P04710 + ADP + ATP --> ADP + ATP 0.0 r_1111 ADP/ATP transporter 1.0879458482506026 prot_Q06497 + ADP + ATP + H+ --> ADP + ATP + H+ 0.0 -r_1112 AKG transporter, mitochonrial 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 0.600337177898591 +r_1112 AKG transporter, mitochonrial 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 0.600434658146268 r_1112_REV AKG transporter, mitochonrial (reversible) 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 0.0 r_1113 allantoate uniport 1.2976708311906466 prot_P15365 + allantoate --> allantoate 0.0 r_1114 allantoin uniport 10.243314336688835 prot_Q04895 + allantoin --> allantoin 0.0 -r_1115_EXP_1 ammonia transport 0.565835007774522 prot_Q12359 + ammonium --> ammonium 0.6583868200646839 +r_1115_EXP_1 ammonia transport 0.565835007774522 prot_Q12359 + ammonium --> ammonium 0.6583315748083954 r_1115_EXP_2 ammonia transport 1.0213597006592061 prot_P40260 + ammonium --> ammonium 0.0 r_1115_EXP_3 ammonia transport 1.006265993411724 prot_P41948 + ammonium --> ammonium 0.0 r_1115_EXP_4 ammonia transport 1.0117117879117519 prot_P53390 + ammonium --> ammonium 0.0 @@ -1351,12 +1351,12 @@ r_1124 ceramide-3 (Phytosphingosine:n-C26:0OH) transport ceramide-3 (C26) --> ce r_1124_REV ceramide-3 (Phytosphingosine:n-C26:0OH) transport (reversible) ceramide-3 (C26) --> ceramide-3 (C26) 0.0 r_1125 choline transport 49.19344031664132 prot_P19807 + choline + H+ --> choline + H+ 0.0 r_1126 citrate transport 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.0 -r_1126_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.15433447811933687 +r_1126_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.1543344781193408 r_1127 citrate transport 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.0 -r_1127_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.03345248332545636 +r_1127_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.03345248332545642 r_1128 citrate transport 0.3417805406736961 prot_P38152 + citrate + isocitrate --> citrate + isocitrate 0.0 r_1128_REV citrate transport (reversible) 0.3417805406736961 prot_P38152 + citrate + isocitrate --> citrate + isocitrate 0.0 -r_1129 coenzyme A transport 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.022126459469045276 +r_1129 coenzyme A transport 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.022126459469173073 r_1130 CTP transport 0.2701553629071786 prot_P38127 + CMP + CTP + H+ --> CMP + CTP + H+ 0.0 r_1131 CTP/CMP antiport 0.2701553629071786 prot_P38127 + CMP + CTP + 2.0 H+ --> CMP + CTP + 2.0 H+ 0.0 r_1132 cytidine transport 19.950758151174124 prot_P31381 + cytidine + H+ --> cytidine + H+ 0.0 @@ -1385,9 +1385,9 @@ r_1135_EXP_3 D-galactose transport 7.895711187219881 prot_P13181 + D-galactose + r_1135_EXP_4 D-galactose transport 9.049001302171312 prot_P42833 + D-galactose + H+ --> D-galactose + H+ 0.0 r_1135_EXP_5 D-galactose transport 0.8760873219329858 prot_P54862 + D-galactose + H+ --> D-galactose + H+ 0.0 r_1136 D-lactate transport 1398.5378967792055 prot_P36035 + (R)-lactate + H+ --> (R)-lactate + H+ 0.0 -r_1137 D-lactate transport (R)-lactate + H+ --> (R)-lactate + H+ 1.1645436644801588 +r_1137 D-lactate transport (R)-lactate + H+ --> (R)-lactate + H+ 1.1646411447276854 r_1138 D-lactate/pyruvate antiport (R)-lactate + pyruvate --> (R)-lactate + pyruvate 0.0 -r_1138_REV D-lactate/pyruvate antiport (reversible) (R)-lactate + pyruvate --> (R)-lactate + pyruvate 1.1645436644801588 +r_1138_REV D-lactate/pyruvate antiport (reversible) (R)-lactate + pyruvate --> (R)-lactate + pyruvate 1.1646411447276854 r_1139_EXP_1 D-mannose transport 21.752276959457756 prot_P54854 + D-mannose + H+ --> D-mannose + H+ 0.0 r_1139_EXP_10 D-mannose transport 5.737789186505133 prot_P40885 + D-mannose + H+ --> D-mannose + H+ 0.0 r_1139_EXP_11 D-mannose transport 24.62776935429521 prot_P47185 + D-mannose + H+ --> D-mannose + H+ 0.0 @@ -1467,7 +1467,7 @@ r_1173_EXP_3 glycine transport 12.596301854889402 prot_P38967 + H+ + L-glycine - r_1173_EXP_4 glycine transport 14.445193920799005 prot_P15380 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_EXP_5 glycine transport 7.968919773312661 prot_P53388 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_1 glycine transport (reversible) 25.955237884466197 prot_P25376 + H+ + L-glycine --> H+ + L-glycine 0.0 -r_1173_REV_EXP_2 glycine transport (reversible) 4.0449974975144505 prot_P19145 + H+ + L-glycine --> H+ + L-glycine 0.008195186854952465 +r_1173_REV_EXP_2 glycine transport (reversible) 4.0449974975144505 prot_P19145 + H+ + L-glycine --> H+ + L-glycine 0.008170545422316523 r_1173_REV_EXP_3 glycine transport (reversible) 12.596301854889402 prot_P38967 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_4 glycine transport (reversible) 14.445193920799005 prot_P15380 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_5 glycine transport (reversible) 9.41498101418254 prot_P53388 + H+ + L-glycine --> H+ + L-glycine 0.0 @@ -1632,17 +1632,17 @@ r_1236 octadecanoate (n-C18:0) transport 28.588907052147633 prot_P34230 + 29.442 r_1236_REV octadecanoate (n-C18:0) transport (reversible) 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + stearate --> stearate 0.0 r_1237 ornithine transport 1.3730998683382918 prot_Q12375 + H+ + ornithine --> H+ + ornithine 0.0194296205196944 r_1238 orntithine transport 1.9804691654008884 prot_P19145 + H+ + ornithine --> H+ + ornithine 0.0 -r_1239 oxaloacetate transport 0.8569958862601018 prot_P32332 + H+ + oxaloacetate --> H+ + oxaloacetate 0.0 +r_1239 oxaloacetate transport 0.8569958862601018 prot_P32332 + H+ + oxaloacetate --> H+ + oxaloacetate 1.7863488466218769e-13 r_1241 pantothenate transport 34.938176452130854 prot_P25621 + (R)-pantothenate + H+ --> (R)-pantothenate + H+ 0.0 r_1242 pentaprenyl diphosphate transport pentaprenyl diphosphate --> pentaprenyl diphosphate 0.0 r_1242_REV pentaprenyl diphosphate transport (reversible) pentaprenyl diphosphate --> pentaprenyl diphosphate 0.0 r_1243 phenethyl acetate transport phenethyl acetate --> phenethyl acetate 0.0 -r_1244_EXP_1 phosphate transport 1.5821717171717171 prot_P38361 + H+ + phosphate --> H+ + phosphate 0.027969546835941717 +r_1244_EXP_1 phosphate transport 1.5821717171717171 prot_P38361 + H+ + phosphate --> H+ + phosphate 0.027937883343042924 r_1244_EXP_2 phosphate transport 2.5893939393939394 prot_P25360 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_3 phosphate transport 2.4668939393939393 prot_P39535 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_4 phosphate transport 1.6258080808080808 prot_P25297 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_5 phosphate transport 2.5123737373737374 prot_P27514 + H+ + phosphate --> H+ + phosphate 0.0 -r_1245_EXP_1 phosphate transport 0.8466666666666667 prot_P40035 + H+ + phosphate --> H+ + phosphate 0.027046249362787655 +r_1245_EXP_1 phosphate transport 0.8466666666666667 prot_P40035 + H+ + phosphate --> H+ + phosphate 0.027046249362174302 r_1245_EXP_2 phosphate transport 0.8285858585858585 prot_P23641 + H+ + phosphate --> H+ + phosphate 0.8149831190629262 r_1249_EXP_1 potassium transport 1.7714141414141413 prot_Q04121 + H+ + potassium --> H+ + potassium 0.000362999993376434 r_1249_EXP_2 potassium transport 3.562449494949495 prot_P12685 + H+ + potassium --> H+ + potassium 0.0 @@ -1686,9 +1686,9 @@ r_1263_REV_EXP_1 spermine transport (reversible) 4.408232799564757 prot_P53283 + r_1263_REV_EXP_2 spermine transport (reversible) 14.118248201928578 prot_Q07824 + H+ + spermine --> H+ + spermine 0.0 r_1263_REV_EXP_3 spermine transport (reversible) 4.735615277275769 prot_Q12256 + H+ + spermine --> H+ + spermine 0.0 r_1263_REV_EXP_4 spermine transport (reversible) 5.6450672243090425 prot_Q06451 + H+ + spermine --> H+ + spermine 0.0 -r_1264 succinate transport 0.32879485380079526 prot_Q06143 + phosphate + succinate --> phosphate + succinate 0.0 -r_1265 succinate-fumarate transport 0.5875590154537462 prot_P33303 + fumarate + succinate --> fumarate + succinate 0.010726833614571302 -r_1266_EXP_1 sulfate uniport 2.4230050505050507 prot_P38359 + sulphate --> sulphate 0.01392491656887419 +r_1264 succinate transport 0.32879485380079526 prot_Q06143 + phosphate + succinate --> phosphate + succinate -1.9645569893089743e-13 +r_1265 succinate-fumarate transport 0.5875590154537462 prot_P33303 + fumarate + succinate --> fumarate + succinate 0.010726833614776441 +r_1266_EXP_1 sulfate uniport 2.4230050505050507 prot_P38359 + sulphate --> sulphate 0.013924916568870616 r_1266_EXP_2 sulfate uniport 2.516439393939394 prot_Q12325 + sulphate --> sulphate 0.0 r_1267 sulfite transport 296.1052693373152 prot_P41930 + sulphite --> sulphite 0.0 r_1268 taurine transport taurine --> taurine 0.0 @@ -1705,7 +1705,7 @@ r_1275 UTP transport 0.3655624733979681 prot_P38127 + FMN + H+ + UMP + UTP --> F r_1276 UTP/UMP antiport 0.3655624733979681 prot_P38127 + 2.0 H+ + UMP + UTP --> 2.0 H+ + UMP + UTP 0.0 r_1277_EXP_1 water diffusion 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_1277_EXP_2 water diffusion 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_1277_REV_EXP_1 water diffusion (reversible) 0.4050171892049932 prot_P0CD90 + H2O --> H2O 4.5829910779044285 +r_1277_REV_EXP_1 water diffusion (reversible) 0.4050171892049932 prot_P0CD90 + H2O --> H2O 4.583086817435297 r_1277_REV_EXP_2 water diffusion (reversible) 0.77827345573678 prot_P0CD91 + H2O --> H2O 0.0 r_1278_EXP_1 zymosterol transport 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 0.0 r_1278_EXP_2 zymosterol transport 254.30179320863886 prot_Q08409 + zymosterol --> zymosterol 0.0 @@ -1763,9 +1763,9 @@ r_1564 2'-deoxyguanosine exchange 2'-deoxyguanosine --> 0.0 r_1565 2'-deoxyinosine exchange 2'-deoxyinosine --> 0.0 r_1566 2'-deoxyuridine exchange 2'-deoxyuridine --> 0.0 r_1567 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.0 -r_1567_REV 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport (reversible) 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.03345248332545636 +r_1567_REV 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport (reversible) 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.03345248332545642 r_1568 2-dehydropantoate transport 2-dehydropantoate --> 2-dehydropantoate 0.0 -r_1568_REV 2-dehydropantoate transport (reversible) 2-dehydropantoate --> 2-dehydropantoate 1.9000000614987463e-05 +r_1568_REV 2-dehydropantoate transport (reversible) 2-dehydropantoate --> 2-dehydropantoate 1.9000000611411882e-05 r_1572 2-isopropylmalate exchange 2-isopropylmalate --> 0.0 r_1573 2-isopropylmalate transport 2-isopropylmalate --> 2-isopropylmalate 0.0 r_1573_REV 2-isopropylmalate transport (reversible) 2-isopropylmalate --> 2-isopropylmalate 0.0 @@ -1782,8 +1782,8 @@ r_1579 2-methylbutanal transport 2-methylbutanal --> 2-methylbutanal 0.0 r_1579_REV 2-methylbutanal transport (reversible) 2-methylbutanal --> 2-methylbutanal 0.0 r_1580 2-methylbutanol exchange 2-methylbutanol --> 0.0 r_1581 2-methylbutyl acetate exchange 2-methylbutyl acetate --> 0.0 -r_1582 2-methylpropanal transport isobutyraldehyde --> isobutyraldehyde 0.0 -r_1582_REV 2-methylpropanal transport (reversible) isobutyraldehyde --> isobutyraldehyde 0.0 +r_1582 2-methylpropanal transport isobutyraldehyde --> isobutyraldehyde 1000.0 +r_1582_REV 2-methylpropanal transport (reversible) isobutyraldehyde --> isobutyraldehyde 1000.0 r_1583 2-methylpropanal transport isobutyraldehyde --> isobutyraldehyde 0.0 r_1583_REV 2-methylpropanal transport (reversible) isobutyraldehyde --> isobutyraldehyde 0.0 r_1585_EXP_1 2-oxobutanoate transporter 3.025147963735379 prot_P53943 + 2-oxobutanoate --> 2-oxobutanoate 0.0265490320174191 @@ -1854,7 +1854,7 @@ r_1629 8-amino-7-oxononanoate exchange 8-amino-7-oxononanoate --> 0.0 r_1630 9H-xanthine exchange 9H-xanthine --> 0.0 r_1631 acetaldehyde exchange acetaldehyde --> 0.0 r_1632 acetaldehyde transport acetaldehyde --> acetaldehyde 0.0 -r_1632_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde -3.767912003883756e-13 +r_1632_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.0 r_1633 acetaldehyde transport acetaldehyde --> acetaldehyde 0.0 r_1633_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.0 r_1634 acetate exchange acetate --> 0.0 @@ -1871,7 +1871,7 @@ r_1642 adenosine 3',5'-bisphosphate transport 0.12463347770546829 prot_Q12251 + r_1642_REV adenosine 3',5'-bisphosphate transport (reversible) 0.12463347770546829 prot_Q12251 + adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0 r_1643 adenosine exchange adenosine --> 0.0 r_1644 ADP transport ADP --> ADP 0.0 -r_1644_REV ADP transport (reversible) ADP --> ADP 0.004927623923655561 +r_1644_REV ADP transport (reversible) ADP --> ADP 0.0 r_1645 ADP transport ADP --> ADP 0.0 r_1645_REV ADP transport (reversible) ADP --> ADP 0.0 r_1647 AKG transporter, peroxisome 2-oxoglutarate --> 2-oxoglutarate 0.0 @@ -1882,14 +1882,14 @@ r_1650 trehalose exchange trehalose --> 0.0 r_1651 alpha-D-glucosamine 6-phosphate exchange alpha-D-glucosamine 6-phosphate --> 0.0 r_1652 alpha-ketoglutarate/malate transporter (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 r_1652_REV alpha-ketoglutarate/malate transporter (reversible) (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 -r_1654 ammonium exchange ammonium <=> -0.6583868200646839 +r_1654 ammonium exchange ammonium <=> -0.6583315748083954 r_1656 AMP transport AMP --> AMP 0.0 r_1656_REV AMP transport (reversible) AMP --> AMP 0.0 r_1657 arginine transport 25.141189431578304 prot_P38279 + H+ + L-arginine --> H+ + L-arginine 0.0 r_1658 asparagine transport 5.8602645666708675 prot_P48813 + L-asparagine --> L-asparagine 0.0 r_1659 aspartate-glutamate transporter L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 r_1659_REV aspartate-glutamate transporter (reversible) L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 -r_1660 ATP diffusion ATP --> ATP 0.004927623923655561 +r_1660 ATP diffusion ATP --> ATP 0.0 r_1660_REV ATP diffusion (reversible) ATP --> ATP 0.0 r_1661 ATP transport ATP --> ATP 0.0 r_1661_REV ATP transport (reversible) ATP --> ATP 0.0 @@ -1898,14 +1898,14 @@ r_1664 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + r_1664_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1665 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + H2O --> bicarbonate + H+ 0.0 r_1665_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 -r_1667 bicarbonate formation 7.346040189125295e-06 prot_P53615 + carbon dioxide + H2O --> bicarbonate + H+ 0.3922394849922255 +r_1667 bicarbonate formation 7.346040189125295e-06 prot_P53615 + carbon dioxide + H2O --> bicarbonate + H+ 0.3922394849922416 r_1667_REV bicarbonate formation (reversible) 7.346040189125295e-06 prot_P53615 + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1668 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + H2O --> bicarbonate + H+ 0.0 r_1668_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1669 bicarbonate transport bicarbonate --> bicarbonate 0.0 r_1669_REV bicarbonate transport (reversible) bicarbonate --> bicarbonate 0.0 r_1671 biotin exchange biotin --> 0.0 -r_1672 carbon dioxide exchange carbon dioxide --> 3.1011301626135506 +r_1672 carbon dioxide exchange carbon dioxide --> 3.1013033160649885 r_1673 carnitine transport (R)-carnitine --> (R)-carnitine 0.0 r_1674 carnitine-acetylcarnitine carrier (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.0 r_1675 CDP transport CDP --> CDP 0.0 @@ -1922,10 +1922,10 @@ r_1680 ceramide transport ceramide-2 (C26) --> ceramide-2 (C26) 0.0 r_1680_REV ceramide transport (reversible) ceramide-2 (C26) --> ceramide-2 (C26) 0.0 r_1681 ceramide transport ceramide-4 (C26) --> ceramide-4 (C26) 0.0 r_1681_REV ceramide transport (reversible) ceramide-4 (C26) --> ceramide-4 (C26) 0.0 -r_1682 cholestenol delta-isomerase, lumped reaction 2.489610027058053 prot_standard + oxygen + S-adenosyl-L-methionine + zymosterol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + 2.0 H2O + S-adenosyl-L-homocysteine 0.003687743244840878 +r_1682 cholestenol delta-isomerase, lumped reaction 2.489610027058053 prot_standard + oxygen + S-adenosyl-L-methionine + zymosterol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + 2.0 H2O + S-adenosyl-L-homocysteine 0.003687743244862164 r_1683 choline exchange choline --> 0.0 r_1684_EXP_1 choline transport 49.19344031664132 prot_P19807 + choline --> choline 0.0 -r_1684_EXP_2 choline transport 4.890140948879145 prot_Q12412 + choline --> choline 0.002827701568400936 +r_1684_EXP_2 choline transport 4.890140948879145 prot_Q12412 + choline --> choline 0.003153248722256296 r_1684_REV_EXP_1 choline transport (reversible) 49.19344031664132 prot_P19807 + choline --> choline 0.0 r_1684_REV_EXP_2 choline transport (reversible) 4.890140948879145 prot_Q12412 + choline --> choline 0.0 r_1685 chorismate pyruvate lyase 0.6162073031087573 prot_standard + chorismate --> 4-hydroxybenzoate + pyruvate 0.0 @@ -1944,8 +1944,8 @@ r_1694_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1695 CO2 transport carbon dioxide --> carbon dioxide 0.0 r_1695_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1696 CO2 transport carbon dioxide --> carbon dioxide 0.0 -r_1696_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 2.0083999713287937 -r_1697 CO2 transport carbon dioxide --> carbon dioxide 3.1011301626135506 +r_1696_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 2.008594931823621 +r_1697 CO2 transport carbon dioxide --> carbon dioxide 3.1013033160649885 r_1697_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1698 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1698_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 @@ -1954,7 +1954,7 @@ r_1699_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 r_1700 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1700_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 r_1702 cytidine exchange cytidine --> 0.0 -r_1703 cytidylate kinase (CMP) 0.015537262872628726 prot_P15700 + ATP + CMP --> ADP + CDP 0.004654584480956464 +r_1703 cytidylate kinase (CMP) 0.015537262872628726 prot_P15700 + ATP + CMP --> ADP + CDP 0.004948468142145608 r_1704 cytidylate kinase (dCMP) 0.0872640791476408 prot_P15700 + ATP + dCMP --> ADP + dCDP 0.0 r_1704_REV cytidylate kinase (dCMP) (reversible) 0.6446121633029441 prot_P15700 + ADP + dCDP --> ATP + dCMP 0.0006000000052154061 r_1705 cytosine exchange cytosine --> 0.0 @@ -1963,7 +1963,7 @@ r_1707_EXP_1 D-arabinose transport 12.279417568370668 prot_P39004 + D-arabinose r_1707_EXP_2 D-arabinose transport 21.95512360185767 prot_P32467 + D-arabinose --> D-arabinose 0.0 r_1707_REV_EXP_1 D-arabinose transport (reversible) 12.279417568370668 prot_P39004 + D-arabinose --> D-arabinose 0.0 r_1707_REV_EXP_2 D-arabinose transport (reversible) 21.95512360185767 prot_P32467 + D-arabinose --> D-arabinose 0.0 -r_1708 D-erythrose 4-phosphate transport D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.03345248332545636 +r_1708 D-erythrose 4-phosphate transport D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.03345248332545642 r_1708_REV D-erythrose 4-phosphate transport (reversible) D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.0 r_1709 D-fructose exchange D-fructose --> 0.0 r_1710 D-galactose exchange D-galactose --> 0.0 @@ -2005,7 +2005,7 @@ r_1732 deoxyguanosine transport 2'-deoxyguanosine --> 2'-deoxyguanosine 0.0 r_1733 deoxyinosine transport 2'-deoxyinosine --> 2'-deoxyinosine 0.0 r_1734 deoxyuridine kinase (ATP:deoxyuridine) 0.9660422049956934 prot_standard + 2'-deoxyuridine + ATP --> ADP + dUMP + H+ 0.0 r_1735 deoxyuridine transport 3.240537611534019 prot_P38196 + 2'-deoxyuridine --> 2'-deoxyuridine 0.0 -r_1736 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 1.9000000614987463e-05 +r_1736 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 1.9000000611411882e-05 r_1737 dGDP transport dGDP --> dGDP 0.0 r_1737_REV dGDP transport (reversible) dGDP --> dGDP 0.0 r_1738 dhnpt transport 7,8-dihydroneopterin --> 7,8-dihydroneopterin 6.3400002545677125e-06 @@ -2030,10 +2030,10 @@ r_1751_REV dUDP diffusion (reversible) dUDP --> dUDP 0.0 r_1752 dUMP transport dUMP --> dUMP 0.0 r_1752_REV dUMP transport (reversible) dUMP --> dUMP 0.0 r_1753 episterol exchange episterol --> 0.0 -r_1754 ergosta-5,6,22,24,(28)-tetraen-3beta-ol transport ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.003687743244840878 +r_1754 ergosta-5,6,22,24,(28)-tetraen-3beta-ol transport ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.003687743244862164 r_1754_REV ergosta-5,6,22,24,(28)-tetraen-3beta-ol transport (reversible) ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 r_1757 ergosterol exchange ergosterol --> 0.0 -r_1758 ergosterol transport ergosterol --> ergosterol 0.0026582900248468 +r_1758 ergosterol transport ergosterol --> ergosterol 0.0 r_1758_REV ergosterol transport (reversible) ergosterol --> ergosterol 0.0 r_1759 ergosterol transport ergosterol --> ergosterol 0.0 r_1759_REV ergosterol transport (reversible) ergosterol --> ergosterol 0.0 @@ -2065,7 +2065,7 @@ r_1790 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ - r_1791 FMN exchange FMN --> 0.0 r_1792 folic acid exchange folate --> 0.0 r_1793 formate exchange formate --> 0.0 -r_1794 formate transport formate --> formate 1.9009937395932097e-13 +r_1794 formate transport formate --> formate 0.0 r_1795 formate transport 21.253027438375998 prot_P53943 + formate --> formate 0.0 r_1795_REV formate transport (reversible) 21.253027438375998 prot_P53943 + formate --> formate 0.0 r_1796 formate transport fumarate --> fumarate 0.0 @@ -2086,9 +2086,9 @@ r_1807 glutathione exchange glutathione --> 0.0 r_1808 glycerol exchange glycerol --> 0.0 r_1809 glycerol-3-phosphate shuttle glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_1809_REV glycerol-3-phosphate shuttle (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 -r_1810 L-glycine exchange L-glycine --> 0.008195186854952465 +r_1810 L-glycine exchange L-glycine --> 0.008170545422316523 r_1811 glycine transport 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 0.0 -r_1811_REV glycine transport (reversible) 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 1.9000000805086837e-05 +r_1811_REV glycine transport (reversible) 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 1.9000000611411886e-05 r_1812 glycoaldehyde transport glycolaldehyde --> glycolaldehyde 0.0 r_1812_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 6.3400002545677125e-06 r_1813 glycoaldehyde transport glycolaldehyde --> glycolaldehyde 0.0 @@ -2107,7 +2107,7 @@ r_1821 guanosine kinase 0.5934259259259259 prot_standard + ATP + guanosine --> A r_1822 guanosine transport guanosine --> guanosine 0.0 r_1823 guanosine transport guanosine --> guanosine 0.0 r_1824 H+ diffusion H+ --> H+ 0.0 -r_1825 H+ diffusion H+ --> H+ 0.007375486489681756 +r_1825 H+ diffusion H+ --> H+ 0.007375486489724328 r_1825_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1826 H+ diffusion H+ --> H+ 0.0 r_1826_REV H+ diffusion (reversible) H+ --> H+ 0.0 @@ -2119,7 +2119,7 @@ r_1830 H+ diffusion H+ --> H+ 0.0 r_1830_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1831 H+ diffusion H+ --> H+ 0.0 r_1831_REV H+ diffusion (reversible) H+ --> H+ 0.0 -r_1832 H+ exchange H+ <=> 0.5763537418505368 +r_1832 H+ exchange H+ <=> 0.5763618235797932 r_1833 hexacosanoyl-CoA transport hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_1833_REV hexacosanoyl-CoA transport (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_1834 hexadecanal exchange hexadecanal --> 0.0 @@ -2133,7 +2133,7 @@ r_1838_EXP_2 homocitrate synthase 10.507993633138625 prot_P48570 + 2-oxoglutarat r_1839 hydrogen peroxide transport hydrogen peroxide --> hydrogen peroxide 0.0 r_1839_REV hydrogen peroxide transport (reversible) hydrogen peroxide --> hydrogen peroxide 0.0 r_1840 hydroxymethylglutaryl-CoA transport 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.0 -r_1840_REV hydroxymethylglutaryl-CoA transport (reversible) 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.02212645946904527 +r_1840_REV hydroxymethylglutaryl-CoA transport (reversible) 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.022126459469172997 r_1841 hypoxanthine exchange hypoxanthine --> 0.0 r_1842 hypoxanthine transport hypoxanthine --> hypoxanthine 0.0 r_1842_REV hypoxanthine transport (reversible) hypoxanthine --> hypoxanthine 0.0 @@ -2323,8 +2323,8 @@ r_1946_REV MIPC transport (reversible) mannosylinositol phosphorylceramide D (C2 r_1947 myo-inositol exchange myo-inositol --> 0.0 r_1952 N,N'-diformyldityrosine exchange N,N'-diformyldityrosine --> 0.0 r_1963 NADP(+) transport NADP(+) --> NADP(+) 0.0 -r_1963_REV NADP(+) transport (reversible) NADP(+) --> NADP(+) 0.007375486489681756 -r_1964 NADPH transport NADPH --> NADPH 0.007375486489681756 +r_1963_REV NADP(+) transport (reversible) NADP(+) --> NADP(+) 0.007375486489724328 +r_1964 NADPH transport NADPH --> NADPH 0.007375486489724328 r_1964_REV NADPH transport (reversible) NADPH --> NADPH 0.0 r_1965 NH3 transport ammonium --> ammonium 0.0 r_1965_REV NH3 transport (reversible) ammonium --> ammonium 0.0 @@ -2340,11 +2340,11 @@ r_1972 NMN transport NMN --> NMN 0.0 r_1974 nucleoside-diphosphatase (dGDP) 0.5934259259259259 prot_standard + dGDP + H2O --> dGMP + H+ + phosphate 0.0 r_1975 nucleoside-triphosphatase (dGTP) 0.5934259259259259 prot_standard + dGTP + H2O --> dGDP + H+ + phosphate 0.0 r_1976 O-acetylcarnintine transport into mitochondria 1.094665810308139 prot_Q12289 + O-acetylcarnitine --> O-acetylcarnitine 0.0 -r_1977 O2 transport oxygen --> oxygen 0.003687743244840878 +r_1977 O2 transport oxygen --> oxygen 0.003687743244862164 r_1977_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1978 O2 transport oxygen --> oxygen 2.6750460216976957 +r_1978 O2 transport oxygen --> oxygen 2.6752397543092297 r_1978_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1979 O2 transport oxygen --> oxygen 2.7298704917698897 +r_1979 O2 transport oxygen --> oxygen 2.730064224381655 r_1979_REV O2 transport (reversible) oxygen --> oxygen 0.0 r_1980 O2 transport oxygen --> oxygen 0.0 r_1980_REV O2 transport (reversible) oxygen --> oxygen 0.0 @@ -2358,7 +2358,7 @@ r_1989 oxaloacetate(2-) exchange oxaloacetate --> 0.0 r_1990 oxidized glutathione uniport 6.850627360229916 prot_P40897 + glutathione disulfide --> glutathione disulfide 0.0 r_1991 oxidized thioredoxin transport TRX1 disulphide --> TRX1 disulphide 0.0 r_1991_REV oxidized thioredoxin transport (reversible) TRX1 disulphide --> TRX1 disulphide 0.0 -r_1992 oxygen exchange oxygen <-- -2.7298704917698897 +r_1992 oxygen exchange oxygen <-- -2.730064224381655 r_1993 palmitate exchange palmitate --> 0.0 r_1994 palmitoleate exchange palmitoleate --> 0.0 r_1995 palmitoyl-CoA transport palmitoyl-CoA --> palmitoyl-CoA 0.0 @@ -2376,7 +2376,7 @@ r_2002_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phen r_2003 phenylacetaldehyde transport phenylacetaldehyde --> phenylacetaldehyde 0.0 r_2003_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phenylacetaldehyde 0.0 r_2004 phenylalanine transport L-phenylalanine --> L-phenylalanine 0.0 -r_2005 phosphate exchange phosphate <=> -0.027969546835941717 +r_2005 phosphate exchange phosphate <=> -0.027937883343042924 r_2008 phosphate transport 2.5123737373737374 prot_P27514 + phosphate --> phosphate 0.0 r_2008_REV phosphate transport (reversible) 2.5123737373737374 prot_P27514 + phosphate --> phosphate 0.0 r_2020 potassium exchange potassium <=> -0.000362999993376434 @@ -2390,10 +2390,10 @@ r_2026 pyridoxamine kinase 0.07735564304461942 prot_P53727 + ATP + pyridoxamine r_2027 pyridoxamine phosphatase 11.27565182849182 prot_standard + H2O + pyridoxamine 5'-phosphate --> phosphate + pyridoxamine 0.0 r_2028 pyridoxine exchange pyridoxine --> 0.0 r_2029 pyridoxine kinase 0.08096311475409836 prot_P39988 + ATP + pyridoxine --> ADP + H+ + pyridoxine 5'-phosphate 0.0 -r_2030 pyrimidine phosphatase 3.5775737902860114 prot_standard + 5-amino-6-(5-phosphoribitylamino)uracil + H2O --> 5-amino-6-(D-ribitylamino)uracil + phosphate 9.999999710999519e-05 +r_2030 pyrimidine phosphatase 3.5775737902860114 prot_standard + 5-amino-6-(5-phosphoribitylamino)uracil + H2O --> 5-amino-6-(D-ribitylamino)uracil + phosphate 9.999999710998968e-05 r_2031 pyrimidine-nucleoside phosphorylase (uracil) 0.9660422049956934 prot_standard + phosphate + uridine --> alpha-D-ribose 1-phosphate(2-) + uracil 0.0 r_2031_REV pyrimidine-nucleoside phosphorylase (uracil) (reversible) 0.9660422049956934 prot_standard + alpha-D-ribose 1-phosphate(2-) + uracil --> phosphate + uridine 0.0 -r_2032 pyrophosphate transport diphosphate --> diphosphate 0.5747374154748881 +r_2032 pyrophosphate transport diphosphate --> diphosphate 0.5752649283630253 r_2032_REV pyrophosphate transport (reversible) diphosphate --> diphosphate 0.0 r_2033 pyruvate exchange pyruvate --> 0.0 r_2034_EXP_1 pyruvate transport 0.010426331697901588 prot_P53157 + 0.011285052581323294 prot_P53311 + H+ + pyruvate --> H+ + pyruvate 0.0 @@ -2411,23 +2411,23 @@ r_2042 S-adenosyl-L-homocysteine transport S-adenosyl-L-homocysteine --> S-adeno r_2042_REV S-adenosyl-L-homocysteine transport (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.0 r_2043 S-adenosyl-L-methionine exchange S-adenosyl-L-methionine --> 0.0 r_2044 S-methyl-L-methionine exchange S-methyl-L-methionine --> 0.0 -r_2045 serine transport 7.412955094957308 prot_P48813 + L-serine --> L-serine 1.9000000805086837e-05 +r_2045 serine transport 7.412955094957308 prot_P48813 + L-serine --> L-serine 1.9000000611411886e-05 r_2045_REV serine transport (reversible) 7.412955094957308 prot_P48813 + L-serine --> L-serine 0.0 r_2046 sn-glycero-3-phosphocholine exchange sn-glycero-3-phosphocholine --> 0.0 r_2049 sodium exchange sodium <=> -0.0003969999961555 r_2050 spermidine acetyltransferase 0.31953703703703706 prot_standard + acetyl-CoA + spermidine --> coenzyme A + H+ + N(1)-acetylspermidine 0.0 r_2051 spermidine exchange spermidine --> 0.0 r_2052 spermine exchange spermine --> 0.0 -r_2053 squalene transport squalene --> squalene 0.003687743244840878 +r_2053 squalene transport squalene --> squalene 0.003687743244862164 r_2053_REV squalene transport (reversible) squalene --> squalene 0.0 -r_2054 squalene-2,3-epoxide transport (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.003687743244840878 +r_2054 squalene-2,3-epoxide transport (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.003687743244862164 r_2054_REV squalene-2,3-epoxide transport (reversible) (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.0 r_2055 stearate exchange stearate --> 0.0 r_2056 succinate exchange succinate --> 0.0 r_2057 succinate transport succinate --> succinate 0.0 r_2057_REV succinate transport (reversible) succinate --> succinate 0.0 r_2058 sucrose exchange sucrose --> 0.0 -r_2060 sulphate exchange sulphate <=> -0.01392491656887419 +r_2060 sulphate exchange sulphate <=> -0.013924916568870616 r_2061 sulphite exchange sulphite --> 0.0 r_2062 taurine exchange taurine --> 0.0 r_2063 tetracosanoyl-CoA transport tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 @@ -2455,7 +2455,7 @@ r_2085_REV tryptophol transport (reversible) tryptophol --> tryptophol 0.0 r_2086 tyrosine transport L-tyrosine --> L-tyrosine 0.0 r_2087 tyrosine transport L-tyrosine --> L-tyrosine 0.0 r_2087_REV tyrosine transport (reversible) L-tyrosine --> L-tyrosine 0.0 -r_2089 UMP transport UMP --> UMP 0.004927623923655561 +r_2089 UMP transport UMP --> UMP 0.0 r_2089_REV UMP transport (reversible) UMP --> UMP 0.0 r_2090 uracil exchange uracil --> 0.0 r_2091 urea exchange urea --> 0.0 @@ -2464,19 +2464,19 @@ r_2093 valine transport L-valine --> L-valine 0.0 r_2093_REV valine transport (reversible) L-valine --> L-valine 0.031460454977486 r_2094_EXP_1 water diffusion 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_2094_EXP_2 water diffusion 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_2094_REV_EXP_1 water diffusion (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.003687743244840878 +r_2094_REV_EXP_1 water diffusion (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.003687743244862164 r_2094_REV_EXP_2 water diffusion (reversible) 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_2095 water diffusion H2O --> H2O 0.0 r_2095_REV water diffusion (reversible) H2O --> H2O 0.0 r_2096 water diffusion H2O --> H2O 0.0 -r_2096_REV water diffusion (reversible) H2O --> H2O 6.956514413284058 +r_2096_REV water diffusion (reversible) H2O --> H2O 6.956975115481074 r_2097 water diffusion H2O --> H2O 0.0 r_2097_REV water diffusion (reversible) H2O --> H2O 0.0 r_2098 water diffusion H2O --> H2O 0.0 r_2098_REV water diffusion (reversible) H2O --> H2O 0.0 r_2099 water diffusion H2O --> H2O 0.0 r_2099_REV water diffusion (reversible) H2O --> H2O 0.0 -r_2100 water exchange H2O <=> 4.5829910779044285 +r_2100 water exchange H2O <=> 4.583086817435297 r_2101 xanthine transport 9H-xanthine --> 9H-xanthine 0.0 r_2101_REV xanthine transport (reversible) 9H-xanthine --> 9H-xanthine 0.0 r_2102 xanthosine exchange xanthosine --> 0.0 @@ -2496,23 +2496,23 @@ r_2111 growth biomass --> 0.1 r_2112 kynurenine aminotransferase 0.06921227197346601 prot_P47039 + L-kynurenine + pyruvate --> H2O + L-alanine + kynurenic acid 0.0 r_2112_REV kynurenine aminotransferase (reversible) 0.009033549783549784 prot_P47039 + H2O + L-alanine + kynurenic acid --> L-kynurenine + pyruvate 0.0 r_2113 spontaneous kynurenic acid to quinaldic acid 0.41264716703458426 prot_standard + 2.0 H+ + NADPH + kynurenic acid --> H2O + NADP(+) + quinaldic acid 0.0 -r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.41264716703458426 prot_standard + 2-amino-3-carboxymuconate-6-semialdehyde --> H+ + H2O + quinolinate 0.0006069999973987722 +r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.41264716703458426 prot_standard + 2-amino-3-carboxymuconate-6-semialdehyde --> H+ + H2O + quinolinate 0.0006069999973988254 r_2115_EXP_1 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.03339649287148808 prot_P38113 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.0 r_2115_EXP_2 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.011373148148148148 prot_P00330 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.0 r_2116_EXP_1 acetaldehyde dehydrogenase 0.06942013888888889 prot_Q04458 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_2 acetaldehyde dehydrogenase 0.483596214511041 prot_P47771 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_3 acetaldehyde dehydrogenase 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_4 acetaldehyde dehydrogenase 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 -r_2117 phenylalanine transaminase 0.05744797801334904 prot_P38840 + L-phenylalanine + pyruvate --> keto-phenylpyruvate + L-alanine 0.046469229158742326 +r_2117 phenylalanine transaminase 0.05744797801334904 prot_P38840 + L-phenylalanine + pyruvate --> keto-phenylpyruvate + L-alanine 0.04646922915874228 r_2117_REV phenylalanine transaminase (reversible) 0.010556998556998556 prot_P38840 + keto-phenylpyruvate + L-alanine --> L-phenylalanine + pyruvate 0.0 r_2118 tryptophan transaminase 0.05744797801334904 prot_P38840 + keto-phenylpyruvate + L-tryptophan --> indole-3-pyruvate + L-phenylalanine 0.0 r_2119 tyrosine transaminase 0.010556998556998556 prot_P38840 + 3-(4-hydroxyphenyl)pyruvate + L-alanine --> L-tyrosine + pyruvate 0.012302566079285501 r_2119_REV tyrosine transaminase (reversible) 0.11696243005595523 prot_P38840 + L-tyrosine + pyruvate --> 3-(4-hydroxyphenyl)pyruvate + L-alanine 0.0 r_2125 coenzyme A: cytoplasm to LP coenzyme A --> coenzyme A 0.0 -r_2125_REV coenzyme A: cytoplasm to LP (reversible) coenzyme A --> coenzyme A 0.0009366864718576414 +r_2125_REV coenzyme A: cytoplasm to LP (reversible) coenzyme A --> coenzyme A 0.0008461544412809927 r_2126 sedoheptulose bisphosphatase 2.051719576719577 prot_P36136 + H2O + sedoheptulose 1,7-bisphosphate --> phosphate + sedoheptulose 7-phosphate 0.0 r_2129 proton leak H+ --> H+ 0.0 -r_2131 isocitrate dehydrogenase 0.47807539682539685 prot_P21954 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.09627284473818554 +r_2131 isocitrate dehydrogenase 0.47807539682539685 prot_P21954 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.09627284473801356 r_2132_EXP_1 oxoglutarate/malate exchange 0.3902368014935992 prot_Q99297 + (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 r_2132_EXP_2 oxoglutarate/malate exchange 2.6118993789038507 prot_Q03028 + (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 r_2134 14-demethyllanosterol exchange 14-demethyllanosterol --> 0.0 @@ -2521,8 +2521,8 @@ r_2136_REV 14-demethyllanosterol transport (reversible) 14-demethyllanosterol -- r_2137 ergosta-5,7,22,24(28)-tetraen-3beta-ol exchange ergosta-5,7,22,24(28)-tetraen-3beta-ol --> 0.0 r_2139 ergosta-5,7,22,24(28)-tetraen-3beta-ol transport ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 r_2139_REV ergosta-5,7,22,24(28)-tetraen-3beta-ol transport (reversible) ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 -r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 27.714912457481013 prot_P07149 + 25.079771343596047 prot_P19097 + acetyl-CoA + 21.0 H+ + 7.0 malonyl-CoA + 14.0 NADPH --> 7.0 carbon dioxide + 7.0 coenzyme A + 7.0 H2O + 14.0 NADP(+) + palmitoyl-CoA 0.015491556978901207 -r_2141 fatty-acyl-CoA synthase (n-C18:0CoA) 50.82022222222222 prot_P07149 + 45.98822222222222 prot_P19097 + acetyl-CoA + 24.0 H+ + 8.0 malonyl-CoA + 16.0 NADPH --> 8.0 carbon dioxide + 8.0 coenzyme A + 8.0 H2O + 16.0 NADP(+) + stearoyl-CoA 0.0008681308649361869 +r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 27.714912457481013 prot_P07149 + 25.079771343596047 prot_P19097 + acetyl-CoA + 21.0 H+ + 7.0 malonyl-CoA + 14.0 NADPH --> 7.0 carbon dioxide + 7.0 coenzyme A + 7.0 H2O + 14.0 NADP(+) + palmitoyl-CoA 0.015491556978903575 +r_2141 fatty-acyl-CoA synthase (n-C18:0CoA) 50.82022222222222 prot_P07149 + 45.98822222222222 prot_P19097 + acetyl-CoA + 24.0 H+ + 8.0 malonyl-CoA + 16.0 NADPH --> 8.0 carbon dioxide + 8.0 coenzyme A + 8.0 H2O + 16.0 NADP(+) + stearoyl-CoA 0.0008681308649361879 r_2142 B-ketoacyl-ACP synthase (acetoacetyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + acetyl-ACP + carboxyacetyl-ACP --> carbon dioxide + ACP1 + acetoacetyl-ACP 0.0 r_2143 B-ketoacyl-ACP synthase (3-oxo-hexanoyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + carboxyacetyl-ACP + butanoyl-ACP --> carbon dioxide + ACP1 + 3-oxo-hexanoyl-ACP 0.0 r_2144 B-ketoacyl-ACP synthase (3-oxo-octanoyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + carboxyacetyl-ACP + hexanoyl-ACP --> carbon dioxide + ACP1 + 3-oxo-octanoyl-ACP 0.0 @@ -2540,7 +2540,7 @@ r_2152 enoyl-ACP reductase (hexanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NA r_2153 enoyl-ACP reductase (octanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NADPH + trans-oct-2-enoyl-ACP --> NADP(+) + octanoyl-ACP 0.0 r_2154 elongase I (3-oxotetradecanoyl-CoA) 0.36517429674617 prot_P39540 + lauroyl-CoA + malonyl-CoA + H+ --> carbon dioxide + coenzyme A + 3-oxotetradecanoyl-CoA 0.0 r_2155 elongase I (3-oxopalmitoyl-CoA) 0.36517429674617 prot_P39540 + malonyl-CoA + H+ + myristoyl-CoA --> carbon dioxide + coenzyme A + 3-oxopalmitoyl-CoA 0.0 -r_2156 elongase II (3-oxooctadecanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + palmitoyl-CoA --> carbon dioxide + coenzyme A + 3-oxooctadecanoyl-CoA 0.0030108725136407297 +r_2156 elongase II (3-oxooctadecanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + palmitoyl-CoA --> carbon dioxide + coenzyme A + 3-oxooctadecanoyl-CoA 0.00301087251364073 r_2157_EXP_1 elongase II or III (3-oxoicosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + stearoyl-CoA --> carbon dioxide + coenzyme A + 3-oxoicosanoyl-CoA 0.0 r_2157_EXP_2 elongase II or III (3-oxoicosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + stearoyl-CoA --> carbon dioxide + coenzyme A + 3-oxoicosanoyl-CoA 0.0 r_2158_EXP_1 elongase II or III (3-oxodocosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + icosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxodocosanoyl-CoA 0.0 @@ -2575,8 +2575,8 @@ r_2178 trans-2-enoyl-CoA reductase (n-C20:0CoA) 102.13333333333334 prot_Q99190 + r_2179 trans-2-enoyl-CoA reductase (n-C22:0CoA) 3.5110799393544463 prot_Q99190 + H+ + NADPH + trans-docos-2-enoyl-CoA --> docosanoyl-CoA + NADP(+) 0.0 r_2180 trans-2-enoyl-CoA reductase (n-C24:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-tetracos-2-enoyl-CoA --> tetracosanoyl-CoA + NADP(+) 0.0 r_2181 trans-2-enoyl-CoA reductase (n-C26:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexacos-2-enoyl-CoA --> NADP(+) + hexacosanoyl-CoA 0.0 -r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 13.846040131031963 prot_P21147 + H+ + palmitoyl-CoA + oxygen + NADH --> 2.0 H2O + palmitoleoyl-CoA(4-) + NAD 0.009327435743165712 -r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 46.3515873015873 prot_P21147 + H+ + stearoyl-CoA + oxygen + NADH --> 2.0 H2O + NAD + oleoyl-CoA 0.003082358642659892 +r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 13.846040131031963 prot_P21147 + H+ + palmitoyl-CoA + oxygen + NADH --> 2.0 H2O + palmitoleoyl-CoA(4-) + NAD 0.009327435743168078 +r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 46.3515873015873 prot_P21147 + H+ + stearoyl-CoA + oxygen + NADH --> 2.0 H2O + NAD + oleoyl-CoA 0.0030823586426598935 r_2184 octanoate (n-C8:0) transport octanoate --> octanoate 0.0 r_2184_REV octanoate (n-C8:0) transport (reversible) octanoate --> octanoate 0.0 r_2185 decanoate (n-C10:0) transport decanoate --> decanoate 0.0 @@ -2605,7 +2605,7 @@ r_2196_REV_EXP_1 fatty-acid--CoA ligase (hexadecanoate), ER membrane (reversible r_2196_REV_EXP_2 fatty-acid--CoA ligase (hexadecanoate), ER membrane (reversible) 4.27578504719294 prot_P30624 + palmitoyl-CoA + AMP + diphosphate --> coenzyme A + ATP + palmitate 0.0 r_2197_EXP_1 fatty-acid--CoA ligase (hexadecenoate), ER membrane 789.6458183044103 prot_P47912 + coenzyme A + ATP + palmitoleate --> palmitoleoyl-CoA(4-) + AMP + diphosphate 0.0 r_2197_EXP_2 fatty-acid--CoA ligase (hexadecenoate), ER membrane 795.767420607649 prot_P30624 + coenzyme A + ATP + palmitoleate --> palmitoleoyl-CoA(4-) + AMP + diphosphate 0.0 -r_2197_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), ER membrane (reversible) 3.189962202455639 prot_P47912 + palmitoleoyl-CoA(4-) + AMP + diphosphate --> coenzyme A + ATP + palmitoleate 0.0 +r_2197_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), ER membrane (reversible) 3.189962202455639 prot_P47912 + palmitoleoyl-CoA(4-) + AMP + diphosphate --> coenzyme A + ATP + palmitoleate 0.0005840846230801193 r_2197_REV_EXP_2 fatty-acid--CoA ligase (hexadecenoate), ER membrane (reversible) 4.583272040765874 prot_P30624 + palmitoleoyl-CoA(4-) + AMP + diphosphate --> coenzyme A + ATP + palmitoleate 0.0 r_2198_EXP_1 fatty-acid--CoA ligase (octadecanoate), ER membrane 740.1053639846743 prot_P47912 + coenzyme A + ATP + stearate --> stearoyl-CoA + AMP + diphosphate 0.0 r_2198_EXP_2 fatty-acid--CoA ligase (octadecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + stearate --> stearoyl-CoA + AMP + diphosphate 0.0 @@ -2627,7 +2627,7 @@ r_2202_REV_EXP_1 fatty-acid--CoA ligase (hexadecanoate), lipid particle (reversi r_2202_REV_EXP_2 fatty-acid--CoA ligase (hexadecanoate), lipid particle (reversible) 4.27578504719294 prot_P30624 + diphosphate + AMP + palmitoyl-CoA --> coenzyme A + ATP + palmitate 0.0 r_2203_EXP_1 fatty-acid--CoA ligase (hexadecenoate), lipid particle 376.2385922203972 prot_P47912 + coenzyme A + ATP + palmitoleate --> diphosphate + AMP + palmitoleoyl-CoA(4-) 0.0 r_2203_EXP_2 fatty-acid--CoA ligase (hexadecenoate), lipid particle 379.1553214416692 prot_P30624 + coenzyme A + ATP + palmitoleate --> diphosphate + AMP + palmitoleoyl-CoA(4-) 0.0 -r_2203_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), lipid particle (reversible) 3.189962202455639 prot_P47912 + diphosphate + AMP + palmitoleoyl-CoA(4-) --> coenzyme A + ATP + palmitoleate 0.0005840846230801192 +r_2203_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), lipid particle (reversible) 3.189962202455639 prot_P47912 + diphosphate + AMP + palmitoleoyl-CoA(4-) --> coenzyme A + ATP + palmitoleate 0.0 r_2203_REV_EXP_2 fatty-acid--CoA ligase (hexadecenoate), lipid particle (reversible) 4.583272040765874 prot_P30624 + diphosphate + AMP + palmitoleoyl-CoA(4-) --> coenzyme A + ATP + palmitoleate 0.0 r_2204_EXP_1 fatty-acid--CoA ligase (octadecanoate), lipid particle 740.1053639846743 prot_P47912 + coenzyme A + ATP + stearate --> diphosphate + AMP + stearoyl-CoA 0.0 r_2204_EXP_2 fatty-acid--CoA ligase (octadecanoate), lipid particle 745.8429118773946 prot_P30624 + coenzyme A + ATP + stearate --> diphosphate + AMP + stearoyl-CoA 0.0 @@ -2752,23 +2752,23 @@ r_2301 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-dodecadienoyl- r_2302 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-tetradecadienoyl-CoA) 0.0026092013888888888 prot_Q08558 + trans-3,cis-5-tetradecadienoyl-CoA --> trans-2,trans-4-tetradecadienoyl-CoA 0.0 r_2303 2,4-dienoyl-CoA reductase (trans-2,trans-4-dodecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-dodecadienoyl-CoA --> NADP(+) + trans-dodec-3-enoyl-CoA 0.0 r_2304 2,4-dienoyl-CoA reductase (trans-2,trans-4-tetradecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-tetradecadienoyl-CoA --> NADP(+) + trans-tetradec-3-enoyl-CoA 0.0 -r_2305 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.7881241393433842 +r_2305 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.788221619591065 r_2305_REV cis-aconitate(3-) to isocitrate (reversible) 0.16582750582750583 prot_P19414 + isocitrate --> cis-aconitate + H2O 0.0 -r_2308_EXP_1 glycerol-3-phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0029769477977060047 +r_2308_EXP_1 glycerol-3-phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.003153248722094766 r_2308_EXP_2 glycerol-3-phosphate acyltransferase (16:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0 -r_2309_EXP_1 glycerol-3-phosphate acyltransferase (16:1), ER membrane 124.56838874829987 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.003176044001541932 +r_2309_EXP_1 glycerol-3-phosphate acyltransferase (16:1), ER membrane 124.56838874829987 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.002958568307600169 r_2309_EXP_2 glycerol-3-phosphate acyltransferase (16:1), ER membrane 121.5898765007065 prot_P36148 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0 -r_2310 glycerol-3-phosphate acyltransferase (18:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + stearoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0 -r_2311 glycerol-3-phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 0.0006312595534128983 +r_2310 glycerol-3-phosphate acyltransferase (18:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + stearoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0005406821613551337 +r_2311 glycerol-3-phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 0.00029749858868157505 r_2312_EXP_1 dihydroxyacetone phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (16:0) 0.0 r_2312_EXP_2 dihydroxyacetone phosphate acyltransferase (16:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + palmitoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (16:0) 0.0 r_2313_EXP_1 dihydroxyacetone phosphate acyltransferase (16:1), ER membrane 165.43182491128994 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (16:1) 0.0 r_2313_EXP_2 dihydroxyacetone phosphate acyltransferase (16:1), ER membrane 161.47624098192227 prot_P36148 + 2.0 H+ + palmitoleoyl-CoA(4-) + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (16:1) 0.0 r_2314 dihydroxyacetone phosphate acyltransferase (18:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + stearoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (18:0) 0.0 r_2315 dihydroxyacetone phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (18:1) 0.0 -r_2316 glycerol-3-phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.00017630092438876115 +r_2316 glycerol-3-phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0 r_2317 glycerol-3-phosphate acyltransferase (16:1), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoleoyl-CoA(4-) --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0 -r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + stearoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0 +r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + stearoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) -2.413499402835443e-13 r_2319 glycerol-3-phosphate acyltransferase (18:1), lipid particle 106.58129459734965 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + oleoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 0.0 r_2320 dihydroxyacetone phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + dihydroxyacetone phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + acylglycerone phosphate (16:0) 0.0 r_2321 dihydroxyacetone phosphate acyltransferase (16:1), lipid particle 97.624883286648 prot_P36148 + dihydroxyacetone phosphate + 2.0 H+ + palmitoleoyl-CoA(4-) --> coenzyme A + acylglycerone phosphate (16:1) 0.0 @@ -2782,27 +2782,27 @@ r_2328 acyl dhap reductase (16:0), lipid particle 0.09115 prot_P40471 + H+ + acy r_2329 acyl dhap reductase (16:1), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (16:1) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (16:1) + NADP(+) 0.0 r_2330 acyl dhap reductase (18:0), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (18:0) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (18:0) + NADP(+) 0.0 r_2331 acyl dhap reductase (18:1), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (18:1) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (18:1) + NADP(+) 0.0 -r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-16:1) 0.0017316028533434762 -r_2333_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0010291220384586568 +r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-16:1) 0.0013978418878904614 +r_2333_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0015391839283004324 r_2333_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.00021622290590387185 -r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 113.27321041547852 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-16:1) 0.003176044001541932 +r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 113.27321041547852 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-16:1) 0.002958568307600169 r_2335_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 r_2335_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 -r_2336 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-16:1) 0.0 +r_2336 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-16:1) 0.0005406821613551337 r_2337_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 r_2337_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 -r_2338 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-16:1) 0.0006312595534128983 +r_2338 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-16:1) 0.00029749858868157505 r_2339_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), ER membrane 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2339_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2340_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0 r_2340_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0 -r_2340_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.00017630092438876115 +r_2340_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0 r_2341_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 r_2341_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 r_2341_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 r_2342_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 r_2342_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 -r_2342_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 +r_2342_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) -2.413499402835443e-13 r_2343_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2343_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2343_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 @@ -2822,12 +2822,12 @@ r_2356 PA phosphatase (1-18:0, 2-16:1), vacuolar membrane 0.0963012769674609 pro r_2357 PA phosphatase (1-18:0, 2-18:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0 r_2358 PA phosphatase (1-18:1, 2-16:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:1, 2-16:1) --> phosphate + diglyceride (1-18:1, 2-16:1) + 2.0 H+ 0.0 r_2359 PA phosphatase (1-18:1, 2-18:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:1, 2-18:1) --> phosphate + diglyceride (1-18:1, 2-18:1) + 2.0 H+ 0.0 -r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + phosphatidate (1-16:0, 2-16:1) + H2O --> phosphate + diglyceride (1-16:0, 2-16:1) + 2.0 H+ 0.0017316028533434762 -r_2361 PA phosphatase (1-16:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:0, 2-18:1) --> phosphate + diglyceride (1-16:0, 2-18:1) + 2.0 H+ 0.0014216458687512897 -r_2362 PA phosphatase (1-16:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-16:1) --> phosphate + diglyceride (1-16:1, 2-16:1) + 2.0 H+ 0.0004994982929750692 +r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + phosphatidate (1-16:0, 2-16:1) + H2O --> phosphate + diglyceride (1-16:0, 2-16:1) + 2.0 H+ 0.0013978418882933414 +r_2361 PA phosphatase (1-16:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:0, 2-18:1) --> phosphate + diglyceride (1-16:0, 2-18:1) + 2.0 H+ 0.0017554068342043043 +r_2362 PA phosphatase (1-16:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-16:1) --> phosphate + diglyceride (1-16:1, 2-16:1) + 2.0 H+ 0.0008461544417636925 r_2363 PA phosphatase (1-16:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-18:1) --> phosphate + diglyceride (1-16:1, 2-18:1) + 2.0 H+ 0.0 r_2364 PA phosphatase (1-18:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-16:1) --> phosphate + diglyceride (1-18:0, 2-16:1) + 2.0 H+ 0.0 -r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0 +r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ -2.413499402835443e-13 r_2366 PA phosphatase (1-18:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:1, 2-16:1) --> phosphate + diglyceride (1-18:1, 2-16:1) + 2.0 H+ 0.0 r_2367 PA phosphatase (1-18:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:1, 2-18:1) --> phosphate + diglyceride (1-18:1, 2-18:1) + 2.0 H+ 0.0 r_2368_EXP_1 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:0), ER membrane 67.08130559354814 prot_P25628 + palmitoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-16:0) 0.0 @@ -2862,7 +2862,7 @@ r_2377_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membran r_2377_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 r_2378_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_2378_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 -r_2378_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 2.8400710743329085e-05 +r_2378_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_2379_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2379_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2379_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 @@ -2880,13 +2880,13 @@ r_2383_EXP_2 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:1), ER membran r_2383_EXP_3 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-16:1) 0.0 r_2384_EXP_1 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), ER membrane 67.08130559354814 prot_P25628 + stearoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-18:0) 0.0 r_2384_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), ER membrane 20.519322196722364 prot_P53629 + stearoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-18:0) 0.0 -r_2384_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-18:0) 0.0003255471536852847 +r_2384_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-18:0) 0.0 r_2385_EXP_1 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membrane 67.08130559354814 prot_P25628 + stearoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 r_2385_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membrane 20.519322196722364 prot_P53629 + stearoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 r_2385_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 r_2386_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 67.08130559354814 prot_P25628 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 r_2386_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 20.519322196722364 prot_P53629 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 -r_2386_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.00047109758223174005 +r_2386_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 r_2387_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 67.08130559354814 prot_P25628 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2387_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 20.519322196722364 prot_P53629 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2387_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 @@ -2936,7 +2936,7 @@ r_2406 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:0), lipid particle 1 r_2407 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:0), lipid particle 14.405495169082126 prot_Q08650 + palmitoyl-CoA + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-16:0) 0.0 r_2408 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-16:1) 0.0 r_2409 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 -r_2410 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 +r_2410 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0005901918669604513 r_2411 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2412 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-18:0, 2-16:1) --> coenzyme A + triglyceride (1-18:0, 2-16:1, 3-16:1) 0.0 r_2413 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-18:0, 2-18:1) --> coenzyme A + triglyceride (1-18:0, 2-18:1, 3-16:1) 0.0 @@ -2944,7 +2944,7 @@ r_2414 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:1), lipid particle 1 r_2415 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-16:1) 0.0 r_2416 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-18:0) 0.0 r_2417 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 -r_2418 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 +r_2418 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0002559625748032411 r_2419 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2420 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-18:0, 2-16:1) --> coenzyme A + triglyceride (1-18:0, 2-16:1, 3-18:0) 0.0 r_2421 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-18:0, 2-18:1) --> coenzyme A + triglyceride (1-18:0, 2-18:1, 3-18:0) 0.0 @@ -2958,13 +2958,13 @@ r_2428 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:1), lipid particle 1 r_2429 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:0, 2-18:1) --> coenzyme A + triglyceride (1-18:0, 2-18:1, 3-18:1) 0.0 r_2430 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:1, 2-16:1) --> coenzyme A + triglyceride (1-18:1, 2-16:1, 3-18:1) 0.0 r_2431 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-18:1) 0.0 -r_2432 CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) 0.0 +r_2432 CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) -4.028799863164956e-13 r_2432_REV CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) --> H+ + phosphatidate (1-16:0, 2-16:1) + CTP 0.0 -r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.002676545708566863 +r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0021124138658364764 r_2433_REV CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) --> H+ + phosphatidate (1-16:1, 2-16:1) + CTP 0.0 -r_2434 CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) 0.0 +r_2434 CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) 0.0005406821613551337 r_2434_REV CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) --> H+ + phosphatidate (1-18:0, 2-16:1) + CTP 0.0 -r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.003458961121813834 +r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.003450747310937871 r_2435_REV CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) --> H+ + phosphatidate (1-18:1, 2-16:1) + CTP 0.0 r_2436 CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0 r_2436_REV CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) --> H+ + phosphatidate (1-16:0, 2-18:1) + CTP 0.0 @@ -2986,17 +2986,17 @@ r_2444 CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane 1.37 r_2444_REV CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) --> CTP + H+ + phosphatidate (1-16:0, 2-18:1) 0.0 r_2445 CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 0.0 r_2445_REV CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) --> CTP + H+ + phosphatidate (1-16:1, 2-18:1) 0.0 -r_2446 PS synthase (1-16:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 -r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0018202640151839164 -r_2448 PS synthase (1-18:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-16:1) 0.003458961121813834 +r_2446 PS synthase (1-16:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-16:1) -4.028799863164956e-13 +r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0012856313616835201 +r_2448 PS synthase (1-18:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0005122426411806854 +r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-16:1) 0.003450747310937871 r_2450 PS synthase (1-16:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 r_2451 PS synthase (1-16:1, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-18:1) 0.0 r_2452 PS synthase (1-18:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-18:1) 0.0 r_2453 PS synthase (1-18:1, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-18:1) 0.0 r_2454 PI synthase (1-16:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:0, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) 0.0 -r_2455 PI synthase (1-16:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) 0.0008562816933829467 -r_2456 PI synthase (1-18:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:0, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 0.0 +r_2455 PI synthase (1-16:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) 0.0008267825041529561 +r_2456 PI synthase (1-18:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:0, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 2.8439520174448325e-05 r_2457 PI synthase (1-18:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 r_2458 PI synthase (1-16:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0 r_2459 PI synthase (1-16:1, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 0.0 @@ -3006,10 +3006,10 @@ r_2462 lysoPI acyltransferase (1-18:0, 2-16:1), ER membrane 128.62503770539482 p r_2462_REV lysoPI acyltransferase (1-18:0, 2-16:1), ER membrane (reversible) 77.56522929804919 prot_P38226 + coenzyme A + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) --> stearoyl-CoA + sn-2-acyl-1-lysophosphatidylinositol (16:1) 0.0 r_2463 lysoPI acyltransferase (1-18:0, 2-18:1), ER membrane 128.62503770539482 prot_P38226 + stearoyl-CoA + sn-2-acyl-1-lysophosphatidylinositol (18:1) --> coenzyme A + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) 0.0 r_2463_REV lysoPI acyltransferase (1-18:0, 2-18:1), ER membrane (reversible) 77.56522929804919 prot_P38226 + coenzyme A + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> stearoyl-CoA + sn-2-acyl-1-lysophosphatidylinositol (18:1) 0.0 -r_2464 PS decarboxylase (1-16:0, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-16:1) 0.0 -r_2465 PS decarboxylase (1-16:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-16:1) 0.0010072557503258324 +r_2464 PS decarboxylase (1-16:0, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-16:1) -4.028799863164956e-13 +r_2465 PS decarboxylase (1-16:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-16:1) 0.00047262309682543594 r_2466 PS decarboxylase (1-18:0, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_2467 PS decarboxylase (1-18:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.0020910418989899585 +r_2467 PS decarboxylase (1-18:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.002625674552893235 r_2468 PS decarboxylase (1-16:0, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_2469 PS decarboxylase (1-16:1, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:1, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2470 PS decarboxylase (1-18:0, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3024,8 +3024,8 @@ r_2478 PS decarboxylase (1-18:0, 2-18:1), Golgi membrane 0.09853409090909093 pro r_2479 PS decarboxylase (1-18:1, 2-18:1), Golgi membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-18:1, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 r_2480 PS decarboxylase (1-16:0, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-16:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-16:1) 0.0 r_2481 PS decarboxylase (1-16:1, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-16:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-16:1) 0.0 -r_2482 PS decarboxylase (1-18:0, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-18:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_2483 PS decarboxylase (1-18:1, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.0013679192228238757 +r_2482 PS decarboxylase (1-18:0, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-18:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-16:1) 0.0005122426411806854 +r_2483 PS decarboxylase (1-18:1, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.0008250727580446362 r_2484 PS decarboxylase (1-16:0, 2-18:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-16:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_2485 PS decarboxylase (1-16:1, 2-18:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-16:1, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2486 PS decarboxylase (1-18:0, 2-18:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-18:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3033,7 +3033,7 @@ r_2487 PS decarboxylase (1-18:1, 2-18:1), vacuolar membrane 0.09853409090909093 r_2488 PE methyltransferase (1-16:0, 2-16:1), ER membrane 1627.5240996397504 prot_P05374 + phosphatidylethanolamine (1-16:0, 2-16:1) + S-adenosyl-L-methionine --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) 0.0 r_2489 PE methyltransferase (1-16:1, 2-16:1), ER membrane 1772.794398518638 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) 0.0 r_2490 PE methyltransferase (1-18:0, 2-16:1), ER membrane 2311.996703472735 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) 0.0 -r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 169.40036397185034 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) 0.0034589611218138346 +r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 169.40036397185034 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) 0.0034507473109378715 r_2492 PE methyltransferase (1-16:0, 2-18:1), ER membrane 1187.9768182494734 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) 0.0 r_2493 PE methyltransferase (1-16:1, 2-18:1), ER membrane 1927.895637345238 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) 0.0 r_2494 PE methyltransferase (1-18:0, 2-18:1), ER membrane 1845.2830881909267 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3041,7 +3041,7 @@ r_2495 PE methyltransferase (1-18:1, 2-18:1), ER membrane 1146.7320397250028 pro r_2496 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) 0.0 r_2497 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) 0.0 r_2498 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) 0.0 -r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) 0.003458961121813834 +r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) 0.003450747310937871 r_2500 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) 0.0 r_2501 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) 0.0 r_2502 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3049,7 +3049,7 @@ r_2503 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-18:1), ER r_2504 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2505 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2506 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:0, 2-16:1) 0.0 -r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-16:1) 0.003458961121813834 +r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-16:1) 0.003450747310937871 r_2508 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_2509 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2510 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:0, 2-18:1) 0.0 @@ -3070,7 +3070,7 @@ r_2524 ethanolaminephosphotransferase (1-16:0, 2-18:1), ER membrane 12.259319894 r_2525 ethanolaminephosphotransferase (1-16:1, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2526 ethanolaminephosphotransferase (1-18:0, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 r_2527 ethanolaminephosphotransferase (1-18:1, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-18:1, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 -r_2528_EXP_1 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.0014060556996581914 +r_2528_EXP_1 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.0013978418882933414 r_2528_EXP_2 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2529_EXP_1 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2529_EXP_2 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-16:1) 0.0 @@ -3078,11 +3078,11 @@ r_2530_EXP_1 cholinephosphotransferase (1-18:0, 2-16:1), ER membrane 12.68654168 r_2530_EXP_2 cholinephosphotransferase (1-18:0, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_2531_EXP_1 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2531_EXP_2 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-16:1) 0.0 -r_2532_EXP_1 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0014216458687512897 +r_2532_EXP_1 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0017554068342043043 r_2532_EXP_2 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_2533_EXP_1 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2533_EXP_2 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0 -r_2534_EXP_1 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0 +r_2534_EXP_1 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) -2.413499402835443e-13 r_2534_EXP_2 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2535_EXP_1 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_2535_EXP_2 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-18:1) 0.0 @@ -4015,7 +4015,7 @@ r_3103 PG phospholipase C (1-16:1, 2-18:1), mitochondrial membrane 0.49034391534 r_3104 PC phospholipase D (1-16:0, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + phosphatidylcholine (1-16:0, 2-16:1) + H2O --> choline + phosphatidate (1-16:0, 2-16:1) 0.0 r_3105 PC phospholipase D (1-16:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-16:1) --> choline + phosphatidate (1-16:1, 2-16:1) 0.0 r_3106 PC phospholipase D (1-18:0, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:0, 2-16:1) --> choline + phosphatidate (1-18:0, 2-16:1) 0.0 -r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:1, 2-16:1) --> choline + phosphatidate (1-18:1, 2-16:1) 0.002827701568400936 +r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:1, 2-16:1) --> choline + phosphatidate (1-18:1, 2-16:1) 0.003153248722256296 r_3108 PC phospholipase D (1-16:0, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:0, 2-18:1) --> choline + phosphatidate (1-16:0, 2-18:1) 0.0 r_3109 PC phospholipase D (1-16:1, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-18:1) --> choline + phosphatidate (1-16:1, 2-18:1) 0.0 r_3110 PC phospholipase D (1-18:0, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:0, 2-18:1) --> choline + phosphatidate (1-18:0, 2-18:1) 0.0 @@ -4627,7 +4627,7 @@ r_3509_REV myristate transport, cytoplasm-ER membrane (reversible) myristate --> r_3510 palmitate transport, cytoplasm-ER membrane palmitate --> palmitate 0.0 r_3510_REV palmitate transport, cytoplasm-ER membrane (reversible) palmitate --> palmitate 0.0 r_3511 palmitoleate transport, cytoplasm-ER membrane palmitoleate --> palmitoleate 0.0 -r_3511_REV palmitoleate transport, cytoplasm-ER membrane (reversible) palmitoleate --> palmitoleate 0.0 +r_3511_REV palmitoleate transport, cytoplasm-ER membrane (reversible) palmitoleate --> palmitoleate 0.0005840846230801193 r_3512 stearate transport, cytoplasm-ER membrane stearate --> stearate 0.0 r_3512_REV stearate transport, cytoplasm-ER membrane (reversible) stearate --> stearate 0.0 r_3513 oleate transport, cytoplasm-ER membrane oleate --> oleate 0.0 @@ -4638,14 +4638,14 @@ r_3515 lauroyl-CoA transport, cytoplasm-ER membrane lauroyl-CoA --> lauroyl-CoA r_3515_REV lauroyl-CoA transport, cytoplasm-ER membrane (reversible) lauroyl-CoA --> lauroyl-CoA 0.0 r_3516 myristoyl-CoA transport, cytoplasm-ER membrane myristoyl-CoA --> myristoyl-CoA 0.0 r_3516_REV myristoyl-CoA transport, cytoplasm-ER membrane (reversible) myristoyl-CoA --> myristoyl-CoA 0.0 -r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane palmitoyl-CoA --> palmitoyl-CoA 0.015315256054512446 +r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane palmitoyl-CoA --> palmitoyl-CoA 0.015491556978903575 r_3517_REV palmitoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3518 palmitoleoyl-CoA transport, cytoplasm-ER membrane palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 -r_3518_REV palmitoleoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0005840846230801192 -r_3519 stearoyl-CoA transport, cytoplasm-ER membrane stearoyl-CoA --> stearoyl-CoA 0.0008681308649361869 +r_3518_REV palmitoleoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0005901918669604513 +r_3519 stearoyl-CoA transport, cytoplasm-ER membrane stearoyl-CoA --> stearoyl-CoA 0.0006121682903742968 r_3519_REV stearoyl-CoA transport, cytoplasm-ER membrane (reversible) stearoyl-CoA --> stearoyl-CoA 0.0 r_3520 oleoyl-CoA transport, cytoplasm-ER membrane oleoyl-CoA --> oleoyl-CoA 0.0 -r_3520_REV oleoyl-CoA transport, cytoplasm-ER membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.00017630092438875988 +r_3520_REV oleoyl-CoA transport, cytoplasm-ER membrane (reversible) oleoyl-CoA --> oleoyl-CoA -2.413494751274392e-13 r_3521 icosanoyl-CoA transport, cytoplasm-ER membrane icosanoyl-CoA --> icosanoyl-CoA 0.0 r_3521_REV icosanoyl-CoA transport, cytoplasm-ER membrane (reversible) icosanoyl-CoA --> icosanoyl-CoA 0.0 r_3522 docosanoyl-CoA transport, cytoplasm-ER membrane docosanoyl-CoA --> docosanoyl-CoA 0.0 @@ -4654,56 +4654,56 @@ r_3523 tetracosanoyl-CoA transport, cytoplasm-ER membrane tetracosanoyl-CoA --> r_3523_REV tetracosanoyl-CoA transport, cytoplasm-ER membrane (reversible) tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 r_3524 hexacosanoyl-CoA transport, cytoplasm-ER membrane hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_3524_REV hexacosanoyl-CoA transport, cytoplasm-ER membrane (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 -r_3525 H+ transport, cytoplasm-ER membrane H+ --> H+ 0.004960194982092669 +r_3525 H+ transport, cytoplasm-ER membrane H+ --> H+ 0.004669843758347751 r_3525_REV H+ transport, cytoplasm-ER membrane (reversible) H+ --> H+ 0.0 r_3526_EXP_1 H2O transport, cytoplasm-ER membrane 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_3526_EXP_2 H2O transport, cytoplasm-ER membrane 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_3526_REV_EXP_1 H2O transport, cytoplasm-ER membrane (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.027830461285291937 +r_3526_REV_EXP_1 H2O transport, cytoplasm-ER membrane (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.027830461285296672 r_3526_REV_EXP_2 H2O transport, cytoplasm-ER membrane (reversible) 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_3527 CO2 transport, cytoplasm-ER membrane carbon dioxide --> carbon dioxide 0.0 -r_3527_REV CO2 transport, cytoplasm-ER membrane (reversible) carbon dioxide --> carbon dioxide 0.0030108725136407297 +r_3527_REV CO2 transport, cytoplasm-ER membrane (reversible) carbon dioxide --> carbon dioxide 0.00301087251364073 r_3528 coenzyme A transport, cytoplasm-ER membrane coenzyme A --> coenzyme A 0.0 -r_3528_REV coenzyme A transport, cytoplasm-ER membrane (reversible) coenzyme A --> coenzyme A 0.01843387388561694 +r_3528_REV coenzyme A transport, cytoplasm-ER membrane (reversible) coenzyme A --> coenzyme A 0.0185244059161995 r_3529 NADPH transport, cytoplasm-ER membrane NADPH --> NADPH 0.006021745027281459 r_3529_REV NADPH transport, cytoplasm-ER membrane (reversible) NADPH --> NADPH 0.0 r_3530 NADP(+) transport, cytoplasm-ER membrane NADP(+) --> NADP(+) 0.0 r_3530_REV NADP(+) transport, cytoplasm-ER membrane (reversible) NADP(+) --> NADP(+) 0.006021745027281459 -r_3531 O2 transport, cytoplasm-ER membrane oxygen --> oxygen 0.012409794385825604 +r_3531 O2 transport, cytoplasm-ER membrane oxygen --> oxygen 0.012409794385827972 r_3531_REV O2 transport, cytoplasm-ER membrane (reversible) oxygen --> oxygen 0.0 -r_3532 NADH transport, cytoplasm-ER membrane NADH --> NADH 0.02347302412034824 +r_3532 NADH transport, cytoplasm-ER membrane NADH --> NADH 0.02347302412041446 r_3532_REV NADH transport, cytoplasm-ER membrane (reversible) NADH --> NADH 0.0 r_3533 NAD transport, cytoplasm-ER membrane NAD --> NAD 0.0 -r_3533_REV NAD transport, cytoplasm-ER membrane (reversible) NAD --> NAD 0.02347302412034824 -r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.006784251352660835 +r_3533_REV NAD transport, cytoplasm-ER membrane (reversible) NAD --> NAD 0.02347302412041446 +r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.006949997779731643 r_3534_REV glycerol 3-phosphate transport, cytoplasm-ER membrane (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3535 dihydroxyacetone phosphate transport, cytoplasm-ER membrane dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3535_REV dihydroxyacetone phosphate transport, cytoplasm-ER membrane (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3536 diphosphate transport, cytoplasm-ER membrane diphosphate --> diphosphate 0.0 -r_3536_REV diphosphate transport, cytoplasm-ER membrane (reversible) diphosphate --> diphosphate 0.006135506830380697 +r_3536_REV diphosphate transport, cytoplasm-ER membrane (reversible) diphosphate --> diphosphate 0.005519758714646482 r_3537 phosphate transport, cytoplasm-ER membrane phosphate --> phosphate 0.0 r_3537_REV phosphate transport, cytoplasm-ER membrane (reversible) phosphate --> phosphate 0.0 -r_3538 CTP transport, cytoplasm-ER membrane CTP --> CTP 0.006135506830380697 +r_3538 CTP transport, cytoplasm-ER membrane CTP --> CTP 0.006103843337726601 r_3538_REV CTP transport, cytoplasm-ER membrane (reversible) CTP --> CTP 0.0 r_3539 CDP transport, cytoplasm-ER membrane CDP --> CDP 0.0 r_3539_REV CDP transport, cytoplasm-ER membrane (reversible) CDP --> CDP 0.0 r_3540 CMP transport, cytoplasm-ER membrane CMP --> CMP 0.0 -r_3540_REV CMP transport, cytoplasm-ER membrane (reversible) CMP --> CMP 0.008963208398790177 +r_3540_REV CMP transport, cytoplasm-ER membrane (reversible) CMP --> CMP 0.009257092059982897 r_3541 CDP-ethanolamine transport, cytoplasm-ER membrane CDP-ethanolamine --> CDP-ethanolamine 0.0 r_3541_REV CDP-ethanolamine transport, cytoplasm-ER membrane (reversible) CDP-ethanolamine --> CDP-ethanolamine 0.0 -r_3542 CDP-choline transport, cytoplasm-ER membrane CDP-choline --> CDP-choline 0.002827701568400936 +r_3542 CDP-choline transport, cytoplasm-ER membrane CDP-choline --> CDP-choline 0.003153248722256296 r_3542_REV CDP-choline transport, cytoplasm-ER membrane (reversible) CDP-choline --> CDP-choline 0.0 r_3543 ATP transport, cytoplasm-ER membrane ATP --> ATP 0.0 -r_3543_REV ATP transport, cytoplasm-ER membrane (reversible) ATP --> ATP 0.0 -r_3544 AMP transport, cytoplasm-ER membrane AMP --> AMP 0.0 +r_3543_REV ATP transport, cytoplasm-ER membrane (reversible) ATP --> ATP 0.0005840846230801193 +r_3544 AMP transport, cytoplasm-ER membrane AMP --> AMP 0.0005840846230801193 r_3544_REV AMP transport, cytoplasm-ER membrane (reversible) AMP --> AMP 0.0 -r_3545 L-serine transport, cytoplasm-ER membrane 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.00527922513699775 +r_3545 L-serine transport, cytoplasm-ER membrane 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.0052486213133991965 r_3545_REV L-serine transport, cytoplasm-ER membrane (reversible) 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.0 -r_3546 myo-inositol transport, cytoplasm-ER membrane myo-inositol --> myo-inositol 0.0008562816933829467 +r_3546 myo-inositol transport, cytoplasm-ER membrane myo-inositol --> myo-inositol 0.0008552220243274044 r_3546_REV myo-inositol transport, cytoplasm-ER membrane (reversible) myo-inositol --> myo-inositol 0.0 -r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.010376883365441503 +r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.010352241932813613 r_3547_REV S-adenosyl-L-methionine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.0 r_3548 S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.0 -r_3548_REV S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.010376883365441503 +r_3548_REV S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.010352241932813613 r_3549 episterol transport, cytoplasm-ER membrane episterol --> episterol 0.0 r_3549_REV episterol transport, cytoplasm-ER membrane (reversible) episterol --> episterol 0.0 r_3550 fecosterol transport, cytoplasm-ER membrane fecosterol --> fecosterol 0.0 @@ -4711,13 +4711,13 @@ r_3550_REV fecosterol transport, cytoplasm-ER membrane (reversible) fecosterol - r_3551 lanosterol transport, cytoplasm-ER membrane lanosterol --> lanosterol 0.0 r_3551_REV lanosterol transport, cytoplasm-ER membrane (reversible) lanosterol --> lanosterol 0.0 r_3552 ergosterol transport, cytoplasm-ER membrane ergosterol --> ergosterol 0.0 -r_3552_REV ergosterol transport, cytoplasm-ER membrane (reversible) ergosterol --> ergosterol 0.0 +r_3552_REV ergosterol transport, cytoplasm-ER membrane (reversible) ergosterol --> ergosterol 0.0026582900248468 r_3553 zymosterol transport, cytoplasm-ER membrane zymosterol --> zymosterol 0.0 r_3553_REV zymosterol transport, cytoplasm-ER membrane (reversible) zymosterol --> zymosterol 0.0 r_3554 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3554_REV diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3555 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 -r_3555_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 +r_3555_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0008461544417636925 r_3556 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3556_REV diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3557 diglyceride (1-18:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 @@ -4733,9 +4733,9 @@ r_3561_REV diglyceride (1-18:1, 2-18:1) transport, cytoplasm-ER membrane (revers r_3562 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) 0.0 r_3562_REV 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) 0.0 r_3563 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) 0.0 -r_3563_REV 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) 0.0008562816933829467 +r_3563_REV 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) 0.0008267825041529562 r_3564 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 0.0 -r_3564_REV 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 0.0 +r_3564_REV 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 2.8439520174448325e-05 r_3565 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 r_3565_REV 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 r_3566 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0 @@ -4751,7 +4751,7 @@ r_3570_REV sn-glycero-3-phosphocholine transport, ER membrane-cytoplasm (reversi r_3571 hexadecanoate (n-C16:0) transport, cytoplasm-lipid particle palmitate --> palmitate 0.0 r_3571_REV hexadecanoate (n-C16:0) transport, cytoplasm-lipid particle (reversible) palmitate --> palmitate 0.0 r_3572 hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle palmitoleate --> palmitoleate 0.0 -r_3572_REV hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle (reversible) palmitoleate --> palmitoleate 0.0005840846230801192 +r_3572_REV hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle (reversible) palmitoleate --> palmitoleate 0.0 r_3573 octadecanoate (n-C18:0) transport, cytoplasm-lipid particle stearate --> stearate 0.0 r_3573_REV octadecanoate (n-C18:0) transport, cytoplasm-lipid particle (reversible) stearate --> stearate 0.0 r_3574 octadecenoate (n-C18:1) transport, cytoplasm-lipid particle oleate --> oleate 0.0 @@ -4760,15 +4760,15 @@ r_3575 lauroyl-CoA transport, cytoplasm-lipid particle lauroyl-CoA --> lauroyl-C r_3575_REV lauroyl-CoA transport, cytoplasm-lipid particle (reversible) lauroyl-CoA --> lauroyl-CoA 0.0 r_3576 myristoyl-CoA transport, cytoplasm-lipid particle myristoyl-CoA --> myristoyl-CoA 0.0 r_3576_REV myristoyl-CoA transport, cytoplasm-lipid particle (reversible) myristoyl-CoA --> myristoyl-CoA 0.0 -r_3577 palmitoyl-CoA transport, cytoplasm-lipid particle palmitoyl-CoA --> palmitoyl-CoA 0.00017630092438876115 +r_3577 palmitoyl-CoA transport, cytoplasm-lipid particle palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3577_REV palmitoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 -r_3578 palmitoleoyl-CoA transport, cytoplasm-lipid particle palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0005840846230801192 +r_3578 palmitoleoyl-CoA transport, cytoplasm-lipid particle palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0005901918669604513 r_3578_REV palmitoleoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 -r_3579 stearoyl-CoA transport, cytoplasm-lipid particle stearoyl-CoA --> stearoyl-CoA 0.0 +r_3579 stearoyl-CoA transport, cytoplasm-lipid particle stearoyl-CoA --> stearoyl-CoA 0.00025596257456189116 r_3579_REV stearoyl-CoA transport, cytoplasm-lipid particle (reversible) stearoyl-CoA --> stearoyl-CoA 0.0 -r_3580 oleoyl-CoA transport, cytoplasm-lipid particle oleoyl-CoA --> oleoyl-CoA 0.00017630092438875988 +r_3580 oleoyl-CoA transport, cytoplasm-lipid particle oleoyl-CoA --> oleoyl-CoA -2.413494751274392e-13 r_3580_REV oleoyl-CoA transport, cytoplasm-lipid particle (reversible) oleoyl-CoA --> oleoyl-CoA 0.0 -r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle glycerol 3-phosphate --> glycerol 3-phosphate 0.00017630092438876115 +r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle glycerol 3-phosphate --> glycerol 3-phosphate -2.413499402835443e-13 r_3581_REV glycerol 3-phosphate transport, cytoplasm-lipid particle (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3582 dihydroxyacetone phosphate transport, cytoplasm-lipid particle dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3582_REV dihydroxyacetone phosphate transport, cytoplasm-lipid particle (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 @@ -4777,14 +4777,14 @@ r_3583_REV NADPH transport, cytoplasm-lipid particle (reversible) NADPH --> NADP r_3584 NADP(+) transport, cytoplasm-lipid particle NADP(+) --> NADP(+) 0.0 r_3584_REV NADP(+) transport, cytoplasm-lipid particle (reversible) NADP(+) --> NADP(+) 0.0 r_3585 ATP transport, cytoplasm-lipid particle ATP --> ATP 0.0 -r_3585_REV ATP transport, cytoplasm-lipid particle (reversible) ATP --> ATP 0.0005840846230801192 -r_3586 AMP transport, cytoplasm-lipid particle AMP --> AMP 0.0005840846230801192 +r_3585_REV ATP transport, cytoplasm-lipid particle (reversible) ATP --> ATP 0.0 +r_3586 AMP transport, cytoplasm-lipid particle AMP --> AMP 0.0 r_3586_REV AMP transport, cytoplasm-lipid particle (reversible) AMP --> AMP 0.0 -r_3587 diphosphate transport, cytoplasm-lipid particle diphosphate --> diphosphate 0.0005840846230801192 +r_3587 diphosphate transport, cytoplasm-lipid particle diphosphate --> diphosphate 0.0 r_3587_REV diphosphate transport, cytoplasm-lipid particle (reversible) diphosphate --> diphosphate 0.0 r_3588 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3588_REV diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3589 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 +r_3589 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0008461544417636925 r_3589_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3590 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3590_REV diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 @@ -4812,10 +4812,10 @@ r_3601 ATP transport, cytoplasm-cell envelope ATP --> ATP 0.0 r_3601_REV ATP transport, cytoplasm-cell envelope (reversible) ATP --> ATP 0.0 r_3602 ADP transport, cytoplasm-cell envelope ADP --> ADP 0.0 r_3602_REV ADP transport, cytoplasm-cell envelope (reversible) ADP --> ADP 0.0 -r_3603 H+ transport, cytoplasm-cell envelope H+ --> H+ 0.002827701568400936 +r_3603 H+ transport, cytoplasm-cell envelope H+ --> H+ 0.003153248722256296 r_3603_REV H+ transport, cytoplasm-cell envelope (reversible) H+ --> H+ 0.0 r_3604_EXP_1 H2O transport, cytoplasm-cell envelope 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 -r_3604_EXP_2 H2O transport, cytoplasm-cell envelope 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.002827701568400936 +r_3604_EXP_2 H2O transport, cytoplasm-cell envelope 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.003153248722256296 r_3604_EXP_3 H2O transport, cytoplasm-cell envelope 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_3604_REV_EXP_1 H2O transport, cytoplasm-cell envelope (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_3604_REV_EXP_2 H2O transport, cytoplasm-cell envelope (reversible) 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0 @@ -4921,7 +4921,7 @@ r_3651_REV ATP transport, cytoplasm-vacuolar membrane (reversible) ATP --> ATP 0 r_3652 ADP transport, cytoplasm-vacuolar membrane ADP --> ADP 0.0 r_3652_REV ADP transport, cytoplasm-vacuolar membrane (reversible) ADP --> ADP 0.0 r_3653 carbon dioxide transport, cytoplasm-vacuolar membrane carbon dioxide --> carbon dioxide 0.0 -r_3653_REV carbon dioxide transport, cytoplasm-vacuolar membrane (reversible) carbon dioxide --> carbon dioxide 0.0013679192228238757 +r_3653_REV carbon dioxide transport, cytoplasm-vacuolar membrane (reversible) carbon dioxide --> carbon dioxide 0.0013373153992253216 r_3654 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) transport, vacuolar membrane-cytoplasm 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) 0.0 r_3654_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) 0.0 r_3655 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) transport, vacuolar membrane-cytoplasm 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) 0.0 @@ -4938,12 +4938,12 @@ r_3660 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transpor r_3660_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) 0.0 r_3661 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 r_3661_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 -r_3662 H2O transport, cytoplasm-Golgi membrane H2O --> H2O 0.003652747015069835 +r_3662 H2O transport, cytoplasm-Golgi membrane H2O --> H2O 0.003999403164019988 r_3662_REV H2O transport, cytoplasm-Golgi membrane (reversible) H2O --> H2O 0.0 r_3663 phosphate transport, cytoplasm-Golgi membrane phosphate --> phosphate 0.0 -r_3663_REV phosphate transport, cytoplasm-Golgi membrane (reversible) phosphate --> phosphate 0.003652747015069835 +r_3663_REV phosphate transport, cytoplasm-Golgi membrane (reversible) phosphate --> phosphate 0.003999403164019988 r_3664 H+ transport, cytoplasm-Golgi membrane H+ --> H+ 0.0 -r_3664_REV H+ transport, cytoplasm-Golgi membrane (reversible) H+ --> H+ 0.00730549403013967 +r_3664_REV H+ transport, cytoplasm-Golgi membrane (reversible) H+ --> H+ 0.007998806328039976 r_3665 carbon dioxide transport, cytoplasm-Golgi membrane carbon dioxide --> carbon dioxide 0.0 r_3665_REV carbon dioxide transport, cytoplasm-Golgi membrane (reversible) carbon dioxide --> carbon dioxide 0.0 r_3666 ATP transport, cytoplasm-Golgi membrane ATP --> ATP 0.0 @@ -4953,7 +4953,7 @@ r_3667_REV ADP transport, cytoplasm-Golgi membrane (reversible) ADP --> ADP 0.0 r_3668 H2O transport, cytoplasm-mitochondrial membrane H2O --> H2O 0.0 r_3668_REV H2O transport, cytoplasm-mitochondrial membrane (reversible) H2O --> H2O 0.0 r_3669 carbon dioxide transport, cytoplasm-mitochondrial membrane carbon dioxide --> carbon dioxide 0.0 -r_3669_REV carbon dioxide transport, cytoplasm-mitochondrial membrane (reversible) carbon dioxide --> carbon dioxide 0.003098297649315791 +r_3669_REV carbon dioxide transport, cytoplasm-mitochondrial membrane (reversible) carbon dioxide --> carbon dioxide 0.0030982976493157907 r_3670 palmitoleoyl-CoA transport, cytoplasm-mitochondrial membrane palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3670_REV palmitoleoyl-CoA transport, cytoplasm-mitochondrial membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3671 oleoyl-CoA transport, cytoplasm-mitochondrial membrane oleoyl-CoA --> oleoyl-CoA 0.0 @@ -4995,9 +4995,9 @@ r_3688_REV TAG (1-16:0, 2-16:1, 3-18:1) transport, ER membrane-lipid particle (r r_3689 TAG (1-16:1, 2-16:1, 3-16:0) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-16:0) --> triglyceride (1-16:1, 2-16:1, 3-16:0) 0.0 r_3689_REV TAG (1-16:1, 2-16:1, 3-16:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-16:0) --> triglyceride (1-16:1, 2-16:1, 3-16:0) 0.0 r_3690 TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 -r_3690_REV TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 +r_3690_REV TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0005901918669604513 r_3691 TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 -r_3691_REV TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 +r_3691_REV TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0002559625748032411 r_3692 TAG (1-16:1, 2-16:1, 3-18:1) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-18:1) --> triglyceride (1-16:1, 2-16:1, 3-18:1) 0.0 r_3692_REV TAG (1-16:1, 2-16:1, 3-18:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-18:1) --> triglyceride (1-16:1, 2-16:1, 3-18:1) 0.0 r_3693 TAG (1-18:0, 2-16:1, 3-16:0) transport, ER membrane-lipid particle triglyceride (1-18:0, 2-16:1, 3-16:0) --> triglyceride (1-18:0, 2-16:1, 3-16:0) 0.0 @@ -5124,11 +5124,11 @@ r_3753 1-acylglycerophosphoethanolamine (18:0) transport, ER membrane-lipid part r_3753_REV 1-acylglycerophosphoethanolamine (18:0) transport, ER membrane-lipid particle (reversible) 1-acylglycerophosphoethanolamine (18:0) --> 1-acylglycerophosphoethanolamine (18:0) 0.0 r_3754 1-acylglycerophosphoethanolamine (18:1) transport, ER membrane-lipid particle 1-acylglycerophosphoethanolamine (18:1) --> 1-acylglycerophosphoethanolamine (18:1) 0.0 r_3754_REV 1-acylglycerophosphoethanolamine (18:1) transport, ER membrane-lipid particle (reversible) 1-acylglycerophosphoethanolamine (18:1) --> 1-acylglycerophosphoethanolamine (18:1) 0.0 -r_3755 phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.00017630092438876115 +r_3755 phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3755_REV phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3756 phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3756_REV phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 +r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) -2.413499402835443e-13 r_3757_REV phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 r_3758 phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3758_REV phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 @@ -5144,29 +5144,29 @@ r_3763 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membr r_3763_REV phosphatidate (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3764 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3764_REV phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3765 phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:0, 2-16:1) --> phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 +r_3765 phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:0, 2-16:1) --> phosphatidyl-L-serine (1-16:0, 2-16:1) -4.028799863164956e-13 r_3765_REV phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-16:1) --> phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 -r_3766 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:1, 2-16:1) --> phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0010072557503258324 +r_3766 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:1, 2-16:1) --> phosphatidyl-L-serine (1-16:1, 2-16:1) 0.00047262309682543594 r_3766_REV phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:1, 2-16:1) --> phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0 r_3767 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 r_3767_REV phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_3768 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0020910418989899585 +r_3768 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.002625674552893235 r_3768_REV phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0 -r_3769 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 -r_3769_REV phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 +r_3769 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 1000.0 +r_3769_REV phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 1000.0 r_3770 phosphatidyl-L-serine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:1, 2-18:1) --> phosphatidyl-L-serine (1-16:1, 2-18:1) 0.0 r_3770_REV phosphatidyl-L-serine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:1, 2-18:1) --> phosphatidyl-L-serine (1-16:1, 2-18:1) 0.0 r_3771 phosphatidyl-L-serine (1-18:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:0, 2-18:1) --> phosphatidyl-L-serine (1-18:0, 2-18:1) 0.0 r_3771_REV phosphatidyl-L-serine (1-18:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-18:0, 2-18:1) --> phosphatidyl-L-serine (1-18:0, 2-18:1) 0.0 r_3772 phosphatidyl-L-serine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:1, 2-18:1) --> phosphatidyl-L-serine (1-18:1, 2-18:1) 0.0 r_3772_REV phosphatidyl-L-serine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-18:1, 2-18:1) --> phosphatidyl-L-serine (1-18:1, 2-18:1) 0.0 -r_3773 phosphatidylethanolamine (1-16:0, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-16:0, 2-16:1) --> phosphatidylethanolamine (1-16:0, 2-16:1) 0.0 +r_3773 phosphatidylethanolamine (1-16:0, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-16:0, 2-16:1) --> phosphatidylethanolamine (1-16:0, 2-16:1) -4.028799863164956e-13 r_3773_REV phosphatidylethanolamine (1-16:0, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:0, 2-16:1) --> phosphatidylethanolamine (1-16:0, 2-16:1) 0.0 -r_3774 phosphatidylethanolamine (1-16:1, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-16:1, 2-16:1) --> phosphatidylethanolamine (1-16:1, 2-16:1) 0.0010072557503258324 +r_3774 phosphatidylethanolamine (1-16:1, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-16:1, 2-16:1) --> phosphatidylethanolamine (1-16:1, 2-16:1) 0.00047262309682543594 r_3774_REV phosphatidylethanolamine (1-16:1, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:1, 2-16:1) --> phosphatidylethanolamine (1-16:1, 2-16:1) 0.0 r_3775 phosphatidylethanolamine (1-18:0, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 r_3775_REV phosphatidylethanolamine (1-18:0, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_3776 phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0020910418989899585 +r_3776 phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.002625674552893235 r_3776_REV phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0 r_3777 phosphatidylethanolamine (1-16:0, 2-18:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_3777_REV phosphatidylethanolamine (1-16:0, 2-18:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 @@ -5193,34 +5193,34 @@ r_3787_REV phosphatidylcholine (1-18:0, 2-18:1) transport, ER membrane-mitochond r_3788 phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:1, 2-18:1) --> phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_3788_REV phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:1, 2-18:1) --> phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_3789 diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3789_REV diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0017316028533434762 +r_3789_REV diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0013978418882933414 r_3790 diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 -r_3790_REV diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0004994982929750692 +r_3790_REV diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0008461544417636925 r_3791 diglyceride (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3791_REV diglyceride (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3792 diglyceride (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3792_REV diglyceride (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3793 diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 -r_3793_REV diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0014216458687512897 +r_3793_REV diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0017554068342043043 r_3794 diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3794_REV diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3795 diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 -r_3795_REV diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 +r_3795_REV diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) -2.413499402835443e-13 r_3796 diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 r_3796_REV diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 -r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0017316028533434762 +r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0013978418882933414 r_3797_REV phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 -r_3798 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0004994982929750692 +r_3798 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0008461544417636925 r_3798_REV phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3799 phosphatidate (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3799_REV phosphatidate (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3800 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3800_REV phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 -r_3801 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0014216458687512897 +r_3801 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0017554068342043043 r_3801_REV phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3802 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3802_REV phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 +r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) -2.413499402835443e-13 r_3803_REV phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 r_3804 phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3804_REV phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 @@ -5324,9 +5324,9 @@ r_3845 phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-vacuolar me r_3845_REV phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-vacuolar membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-16:1) --> phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 r_3846 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-vacuolar membrane phosphatidyl-L-serine (1-16:1, 2-16:1) --> phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0 r_3846_REV phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-vacuolar membrane (reversible) phosphatidyl-L-serine (1-16:1, 2-16:1) --> phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0 -r_3847 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-vacuolar membrane phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 +r_3847 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-vacuolar membrane phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0005122426411806854 r_3847_REV phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-vacuolar membrane (reversible) phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_3848 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-vacuolar membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0013679192228238757 +r_3848 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-vacuolar membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0008250727580446362 r_3848_REV phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-vacuolar membrane (reversible) phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0 r_3849 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-vacuolar membrane phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 r_3849_REV phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-vacuolar membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 @@ -5340,9 +5340,9 @@ r_3853 phosphatidylethanolamine (1-16:0, 2-16:1) transport, vacuolar membrane-ER r_3853_REV phosphatidylethanolamine (1-16:0, 2-16:1) transport, vacuolar membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:0, 2-16:1) --> phosphatidylethanolamine (1-16:0, 2-16:1) 0.0 r_3854 phosphatidylethanolamine (1-16:1, 2-16:1) transport, vacuolar membrane-ER membrane phosphatidylethanolamine (1-16:1, 2-16:1) --> phosphatidylethanolamine (1-16:1, 2-16:1) 0.0 r_3854_REV phosphatidylethanolamine (1-16:1, 2-16:1) transport, vacuolar membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:1, 2-16:1) --> phosphatidylethanolamine (1-16:1, 2-16:1) 0.0 -r_3855 phosphatidylethanolamine (1-18:0, 2-16:1) transport, vacuolar membrane-ER membrane phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 +r_3855 phosphatidylethanolamine (1-18:0, 2-16:1) transport, vacuolar membrane-ER membrane phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0005122426411806854 r_3855_REV phosphatidylethanolamine (1-18:0, 2-16:1) transport, vacuolar membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_3856 phosphatidylethanolamine (1-18:1, 2-16:1) transport, vacuolar membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0013679192228238757 +r_3856 phosphatidylethanolamine (1-18:1, 2-16:1) transport, vacuolar membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0008250727580446362 r_3856_REV phosphatidylethanolamine (1-18:1, 2-16:1) transport, vacuolar membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0 r_3857 phosphatidylethanolamine (1-16:0, 2-18:1) transport, vacuolar membrane-ER membrane phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_3857_REV phosphatidylethanolamine (1-16:0, 2-18:1) transport, vacuolar membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 @@ -5390,7 +5390,7 @@ r_3878 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope r_3878_REV phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_3879 phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_3879_REV phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 -r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.002827701568400936 +r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.003153248722256296 r_3880_REV phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_3881 phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_3881_REV phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 @@ -5442,7 +5442,7 @@ r_3904 phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane phosp r_3904_REV phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3905 phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3905_REV phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 -r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.002827701568400936 +r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.003153248722256296 r_3906_REV phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3907 phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3907_REV phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 @@ -5508,7 +5508,7 @@ r_3937 lignoceric acid transport, ER membrane-ER lignoceric acid --> lignoceric r_3937_REV lignoceric acid transport, ER membrane-ER (reversible) lignoceric acid --> lignoceric acid 0.0 r_3938 cerotic acid transport, ER membrane-ER cerotic acid --> cerotic acid 0.0 r_3938_REV cerotic acid transport, ER membrane-ER (reversible) cerotic acid --> cerotic acid 0.0 -r_3939 ergosterol transport, ER-ER membrane ergosterol --> ergosterol 0.0010294532199940777 +r_3939 ergosterol transport, ER-ER membrane ergosterol --> ergosterol 0.003687743244862164 r_3939_REV ergosterol transport, ER-ER membrane (reversible) ergosterol --> ergosterol 0.0 r_3940 phosphate transport, ER-ER membrane phosphate --> phosphate 0.0 r_3941 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) transport, vacuolar membrane-Golgi membrane 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) 0.0 @@ -5558,19 +5558,19 @@ r_3961_REV_EXP_2 phosphate transport, mitochondrion-mitochondrial membrane (reve r_3962 diphosphate transport, mitochondrion-mitochondrial membrane diphosphate --> diphosphate 0.0 r_3962_REV diphosphate transport, mitochondrion-mitochondrial membrane (reversible) diphosphate --> diphosphate 0.0 r_3963 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) --> 0.809028342 1-phosphatidyl-1D-myo-inositol backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0 -r_3964 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) --> 0.807012462 1-phosphatidyl-1D-myo-inositol backbone + 0.508826 C16:1 chain 0.0008562816933829467 -r_3965 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 +r_3964 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) --> 0.807012462 1-phosphatidyl-1D-myo-inositol backbone + 0.508826 C16:1 chain 0.0008267825041529562 +r_3965 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 2.8439520174448325e-05 r_3966 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_3967 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0 r_3968 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_3969 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> 0.865135862 1-phosphatidyl-1D-myo-inositol backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_3970 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> 0.863119982 1-phosphatidyl-1D-myo-inositol backbone + 0.56493352 C18:1 chain 0.0 -r_3971 ergosteryl palmitoleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl palmitoleate --> 0.63305448 ergosterol ester backbone + 0.254413 C16:1 chain -5.016277912934027e-13 -r_3972 ergosteryl oleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl oleate --> 0.66110824 ergosterol ester backbone + 0.28246676 C18:1 chain 0.0010294532204957055 +r_3971 ergosteryl palmitoleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl palmitoleate --> 0.63305448 ergosterol ester backbone + 0.254413 C16:1 chain 0.0 +r_3972 ergosteryl oleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl oleate --> 0.66110824 ergosterol ester backbone + 0.28246676 C18:1 chain 0.0010294532200153638 r_3973 ergosterol ester transport, ER membrane-cytoplasm ergosterol ester backbone --> ergosterol ester backbone 0.00068058000644669 r_3973_REV ergosterol ester transport, ER membrane-cytoplasm (reversible) ergosterol ester backbone --> ergosterol ester backbone 0.0 r_3975 palmitate [cytoplasm] SLIME rxn H+ + palmitate --> 0.25542094 fatty acid backbone + 0.25642888 C16:0 chain 0.0 -r_3976 palmitoleate [cytoplasm] SLIME rxn H+ + palmitoleate --> 0.25340506 fatty acid backbone + 0.254413 C16:1 chain 0.0005840846230801192 +r_3976 palmitoleate [cytoplasm] SLIME rxn H+ + palmitoleate --> 0.25340506 fatty acid backbone + 0.254413 C16:1 chain 0.0005840846230801193 r_3977 stearate [cytoplasm] SLIME rxn H+ + stearate --> 0.2834747 fatty acid backbone + 0.28448264 C18:0 chain 0.0 r_3978 oleate [cytoplasm] SLIME rxn H+ + oleate --> 0.28145882 fatty acid backbone + 0.28246676 C18:1 chain 0.0 r_3979 phosphatidyl-L-serine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:0, 2-16:1) --> 0.733964182 phosphatidyl-L-serine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0 @@ -5583,19 +5583,19 @@ r_3985 phosphatidyl-L-serine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] S r_3986 phosphatidyl-L-serine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:1, 2-18:1) --> 0.788055822 phosphatidyl-L-serine backbone + 0.56493352 C18:1 chain 0.0 r_3987 phosphatidyl-L-serine transport, ER membrane-cytoplasm phosphatidyl-L-serine backbone --> phosphatidyl-L-serine backbone 0.000595080018974841 r_3987_REV phosphatidyl-L-serine transport, ER membrane-cytoplasm (reversible) phosphatidyl-L-serine backbone --> phosphatidyl-L-serine backbone 0.0 -r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-16:1) --> 0.732035022 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0014060556996581914 +r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-16:1) --> 0.732035022 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0013978418882933414 r_3989 phosphatidylcholine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-16:1) --> 0.730019142 phosphatidylcholine backbone + 0.508826 C16:1 chain 0.0 r_3990 phosphatidylcholine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-16:1) --> 0.744089382 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 -r_3991 phosphatidylcholine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-16:1) --> 0.742073502 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0006312595534128983 -r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-18:1) --> 0.760088782 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0014216458687512897 +r_3991 phosphatidylcholine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-16:1) --> 0.742073502 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.00029749858868157505 +r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-18:1) --> 0.760088782 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0017554068342043043 r_3993 phosphatidylcholine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-18:1) --> 0.758072902 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-18:1) --> 0.772143142 phosphatidylcholine backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 +r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-18:1) --> 0.772143142 phosphatidylcholine backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain -2.413499402835443e-13 r_3995 phosphatidylcholine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-18:1) --> 0.770127262 phosphatidylcholine backbone + 0.56493352 C18:1 chain 0.0 r_3996 phosphatidylcholine transport, ER membrane-cytoplasm phosphatidylcholine backbone --> phosphatidylcholine backbone 0.0025783000793308 r_3996_REV phosphatidylcholine transport, ER membrane-cytoplasm (reversible) phosphatidylcholine backbone --> phosphatidylcholine backbone 0.0 -r_3997 phosphatidylethanolamine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylethanolamine (1-16:0, 2-16:1) --> 0.689954382 phosphatidylethanolamine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0 -r_3998 phosphatidylethanolamine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylethanolamine (1-16:1, 2-16:1) --> 0.687938502 phosphatidylethanolamine backbone + 0.508826 C16:1 chain 0.0010072557503258324 -r_3999 phosphatidylethanolamine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylethanolamine (1-18:0, 2-16:1) --> 0.718008142 phosphatidylethanolamine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 +r_3997 phosphatidylethanolamine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylethanolamine (1-16:0, 2-16:1) --> 0.689954382 phosphatidylethanolamine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain -4.028799863164956e-13 +r_3998 phosphatidylethanolamine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylethanolamine (1-16:1, 2-16:1) --> 0.687938502 phosphatidylethanolamine backbone + 0.508826 C16:1 chain 0.00047262309682543594 +r_3999 phosphatidylethanolamine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylethanolamine (1-18:0, 2-16:1) --> 0.718008142 phosphatidylethanolamine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0005122426411806854 r_4000 phosphatidylethanolamine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylethanolamine (1-18:1, 2-16:1) --> 0.715992262 phosphatidylethanolamine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_4001 phosphatidylethanolamine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylethanolamine (1-16:0, 2-18:1) --> 0.718008142 phosphatidylethanolamine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0 r_4002 phosphatidylethanolamine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylethanolamine (1-16:1, 2-18:1) --> 0.715992262 phosphatidylethanolamine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 @@ -5613,15 +5613,15 @@ r_4012 triglyceride (1-18:1, 2-16:1, 3-16:0) [endoplasmic reticulum membrane] SL r_4013 triglyceride (1-18:1, 2-18:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-16:0) --> 0.85941128 triglyceride backbone + 0.25642888 C16:0 chain + 0.56493352 C18:1 chain 0.0 r_4014 triglyceride (1-16:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-16:1) --> 0.80330376 triglyceride backbone + 0.25642888 C16:0 chain + 0.508826 C16:1 chain 0.0 r_4015 triglyceride (1-16:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-18:1, 3-16:1) --> 0.83135752 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-16:1) --> 0.80128788 triglyceride backbone + 0.763239 C16:1 chain 2.8400710743329085e-05 +r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-16:1) --> 0.80128788 triglyceride backbone + 0.763239 C16:1 chain 0.0005901918669604513 r_4017 triglyceride (1-16:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-18:1, 3-16:1) --> 0.82934164 triglyceride backbone + 0.508826 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_4018 triglyceride (1-18:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-16:1, 3-16:1) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_4019 triglyceride (1-18:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-18:1, 3-16:1) --> 0.85941128 triglyceride backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_4020 triglyceride (1-18:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-16:1, 3-16:1) --> 0.82934164 triglyceride backbone + 0.508826 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_4021 triglyceride (1-18:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-16:1) --> 0.8573954 triglyceride backbone + 0.254413 C16:1 chain + 0.56493352 C18:1 chain 0.0 -r_4022 triglyceride (1-16:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-18:0) --> 0.8333734 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0003255471536852847 +r_4022 triglyceride (1-16:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-18:0) --> 0.8333734 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_4023 triglyceride (1-16:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-18:1, 3-18:0) --> 0.86142716 triglyceride backbone + 0.25642888 C16:0 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 -r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-18:0) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.00047109758223174005 +r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-18:0) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0002559625748032411 r_4025 triglyceride (1-16:1, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-18:1, 3-18:0) --> 0.85941128 triglyceride backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_4026 triglyceride (1-18:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-16:1, 3-18:0) --> 0.86142716 triglyceride backbone + 0.254413 C16:1 chain + 0.56896528 C18:0 chain 0.0 r_4027 triglyceride (1-18:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-18:1, 3-18:0) --> 0.88948092 triglyceride backbone + 0.56896528 C18:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5637,7 +5637,7 @@ r_4036 triglyceride (1-18:1, 2-16:1, 3-18:1) [endoplasmic reticulum membrane] SL r_4037 triglyceride (1-18:1, 2-18:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-18:1) --> 0.88544916 triglyceride backbone + 0.84740028 C18:1 chain 0.0 r_4038 triglyceride transport, ER membrane-cytoplasm triglyceride backbone --> triglyceride backbone 0.0006857100012712191 r_4038_REV triglyceride transport, ER membrane-cytoplasm (reversible) triglyceride backbone --> triglyceride backbone 0.0 -r_4039 succinyl-CoA:acetate CoA transferase 2.0420759036703515 prot_P32316 + acetate + succinyl-CoA --> acetyl-CoA + succinate -3.767912003883756e-13 +r_4039 succinyl-CoA:acetate CoA transferase 2.0420759036703515 prot_P32316 + acetate + succinyl-CoA --> acetyl-CoA + succinate 0.0 r_4039_REV succinyl-CoA:acetate CoA transferase (reversible) 2.24640342822161 prot_P32316 + acetyl-CoA + succinate --> acetate + succinyl-CoA 0.0 r_4040 heme a transport heme a --> heme a 0.0 r_4040_REV heme a transport (reversible) heme a --> heme a 0.0 @@ -5904,7 +5904,7 @@ r_4195_EXP_1 Zinc transporter YKE4 1.2208333333333334 prot_P20107 + Zn(2+) --> Z r_4195_EXP_2 Zinc transporter YKE4 1.2160353535353536 prot_P32798 + Zn(2+) --> Zn(2+) 0.0 r_4195_REV_EXP_1 Zinc transporter YKE4 (reversible) 1.2208333333333334 prot_P20107 + Zn(2+) --> Zn(2+) 0.0 r_4195_REV_EXP_2 Zinc transporter YKE4 (reversible) 1.2160353535353536 prot_P32798 + Zn(2+) --> Zn(2+) 0.0 -r_4196_EXP_1 NADH:ferricytochrome-b5 oxidoreductase 0.007953030303030304 prot_P38626 + NADH + 2.0 ferricytochrome b5 --> H+ + NAD + 2.0 ferrocytochrome b5 0.011063229734522635 +r_4196_EXP_1 NADH:ferricytochrome-b5 oxidoreductase 0.007953030303030304 prot_P38626 + NADH + 2.0 ferricytochrome b5 --> H+ + NAD + 2.0 ferrocytochrome b5 0.011063229734586491 r_4196_EXP_2 NADH:ferricytochrome-b5 oxidoreductase 0.008910858585858586 prot_Q12746 + NADH + 2.0 ferricytochrome b5 --> H+ + NAD + 2.0 ferrocytochrome b5 0.0 r_4196_REV_EXP_1 NADH:ferricytochrome-b5 oxidoreductase (reversible) 0.02916111111111111 prot_P38626 + H+ + NAD + 2.0 ferrocytochrome b5 --> NADH + 2.0 ferricytochrome b5 0.0 r_4196_REV_EXP_2 NADH:ferricytochrome-b5 oxidoreductase (reversible) 0.032673148148148146 prot_Q12746 + H+ + NAD + 2.0 ferrocytochrome b5 --> NADH + 2.0 ferricytochrome b5 0.0 @@ -5944,7 +5944,7 @@ r_4212_REV_EXP_2 D-ribulose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5 r_4214 L-cysteinylglycine dipeptidase 0.44291358035466905 prot_P43616 + H2O + L-cysteinylglycine --> L-cysteine + L-glycine 0.0 r_4214_REV L-cysteinylglycine dipeptidase (reversible) 1.1513279129330525 prot_P43616 + L-cysteine + L-glycine --> H2O + L-cysteinylglycine 0.0 r_4216 riboflavin-5-phosphate phosphohydrolase 2.307741115456161 prot_P52290 + FMN + H2O --> phosphate + riboflavin 0.0 -r_4216_REV riboflavin-5-phosphate phosphohydrolase (reversible) 1.7221699633075207 prot_P52290 + phosphate + riboflavin --> FMN + H2O 9.99999974743372e-07 +r_4216_REV riboflavin-5-phosphate phosphohydrolase (reversible) 1.7221699633075207 prot_P52290 + phosphate + riboflavin --> FMN + H2O 9.99999974737875e-07 r_4217 Fe(II):oxygen oxidoreductase; Fe2+:oxygen oxidoreductase 2.4608585858585856 prot_Q07540 + 4.0 H+ + 4.0 iron(2+) + oxygen --> 2.0 H2O + 4.0 iron(3+) 0.0 r_4217_REV Fe(II):oxygen oxidoreductase; Fe2+:oxygen oxidoreductase (reversible) 2.4608585858585856 prot_Q07540 + 2.0 H2O + 4.0 iron(3+) --> 4.0 H+ + 4.0 iron(2+) + oxygen 0.0 r_4218 D-aminoacyl-tRNA deacylase (DTD) (EC 3.1.1.96) (D-tyrosyl-tRNA(Tyr) deacylase) (Gly-tRNA(Ala) deacylase) (EC 3.1.1.-) 0.015505555555555555 prot_Q07648 + H2O + Glycyl-tRNA(Ala) --> H+ + L-glycine + tRNA(Ala) 0.0 @@ -6136,7 +6136,7 @@ r_4332 Protein PNS1 (pH nine-sensitive protein 1) 4.890140948879145 prot_Q12412 r_4332_REV Protein PNS1 (pH nine-sensitive protein 1) (reversible) 4.890140948879145 prot_Q12412 + choline --> choline 0.0 r_4333_EXP_1 Polyphosphate phosphohydrolase 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4333_EXP_2 Polyphosphate phosphohydrolase 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 -r_4333_REV_EXP_1 Polyphosphate phosphohydrolase (reversible) 0.008073655913978494 prot_P38698 + H+ + 2.0 phosphate --> H2O + polyphosphate 0.7519988664435606 +r_4333_REV_EXP_1 Polyphosphate phosphohydrolase (reversible) 0.008073655913978494 prot_P38698 + H+ + 2.0 phosphate --> H2O + polyphosphate 0.7518370312720519 r_4333_REV_EXP_2 Polyphosphate phosphohydrolase (reversible) 0.014040143369175627 prot_Q04119 + H+ + 2.0 phosphate --> H2O + polyphosphate 1.9297163192902698 r_4334 Copper-transporting ATPase (EC 3.6.3.54) (Cu(2+)-ATPase) 117.33867521367522 prot_P38995 + ATP + H2O + Cu2(+) --> ADP + H+ + phosphate + Cu2(+) 0.0 r_4335 Endopolyphosphatase (EC 3.6.1.10) (Deoxyadenosine triphosphate phosphohydrolase) (dATP phosphohydrolase) (EC 3.6.1.-) (Exopolyphosphatase) (EC 3.6.1.11) (Phosphate metabolism protein 5) 0.014040143369175627 prot_Q04119 + dATP + H2O --> dADP + H+ + phosphate 0.0 @@ -6481,17 +6481,17 @@ r_4567 6-phosphogluconate phosphatase 0.17308256172839506 prot_standard + 6-phos r_4569 Carboxylic ester hydrolases 0.45405614353626883 prot_standard + acetate + H+ + Hydroquinone --> H2O + 4-hydroxyphenyl acetate 0.0 r_4570_EXP_1 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + NAD + 2-hydroxyglutarate --> 2-oxoglutarate + H+ + NADH 0.0 r_4570_EXP_2 phosphoglycerate dehydrogenase 0.0036935786435786434 prot_P40054 + NAD + 2-hydroxyglutarate --> 2-oxoglutarate + H+ + NADH 0.0 -r_4570_REV_EXP_1 phosphoglycerate dehydrogenase (reversible) 0.005777687480247415 prot_P40510 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.022773982051119843 +r_4570_REV_EXP_1 phosphoglycerate dehydrogenase (reversible) 0.005777687480247415 prot_P40510 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.02277398205112342 r_4570_REV_EXP_2 phosphoglycerate dehydrogenase (reversible) 0.0057782518398121815 prot_P40054 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.0 -r_4571 seed:rxn00681 1.1329040404040405 prot_standard + coenzyme A + H+ + 2-hydroxyglutarate --> glyoxylate + H2O + propionyl-CoA 0.022773982051119843 +r_4571 seed:rxn00681 1.1329040404040405 prot_standard + coenzyme A + H+ + 2-hydroxyglutarate --> glyoxylate + H2O + propionyl-CoA 0.02277398205112342 r_4571_REV seed:rxn00681 (reversible) 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + 2-hydroxyglutarate 0.0 r_4572 beta-alanine:2-oxoglutarate aminotransferase 1.1329040404040405 prot_standard + 2-oxoglutarate + beta-alanine --> L-glutamate + 3-oxopropanoate 0.0 r_4572_REV beta-alanine:2-oxoglutarate aminotransferase (reversible) 1.1329040404040405 prot_standard + L-glutamate + 3-oxopropanoate --> 2-oxoglutarate + beta-alanine 0.0 r_4573 3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NAD + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADH 0.0 r_4574 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NADP(+) + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADPH 0.0 r_4575 3-oxopropanoate carboxy-lyase 0.45405614353626883 prot_standard + H+ + 3-oxopropanoate --> acetaldehyde + carbon dioxide 0.0 -r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.048490056204063985 prot_standard + NAD + (2R,3S)-3-methylmalate --> 2-oxobutanoate + carbon dioxide + NADH 0.022773982051119843 -r_4582 malate/beta-methylmalate synthase 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + (2R,3S)-3-methylmalate 0.022773982051119843 +r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.048490056204063985 prot_standard + NAD + (2R,3S)-3-methylmalate --> 2-oxobutanoate + carbon dioxide + NADH 0.02277398205112342 +r_4582 malate/beta-methylmalate synthase 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + (2R,3S)-3-methylmalate 0.02277398205112342 r_4583 palmitoyl-CoA hydrolase 2.0068374645606704 prot_standard + H2O + trans-2,cis-9-octadecadienoyl-CoA --> coenzyme A + H+ + (9Z,12Z)-octadecadienoate 0.0 r_4584_EXP_1 long-chain-fatty-acid---CoA ligase 745.8429118773946 prot_P30624 + ATP + coenzyme A + (9Z,12Z)-octadecadienoate --> AMP + diphosphate + trans-2,cis-9-octadecadienoyl-CoA 0.0 r_4584_EXP_2 long-chain-fatty-acid---CoA ligase 799.2145593869732 prot_P39518 + ATP + coenzyme A + (9Z,12Z)-octadecadienoate --> AMP + diphosphate + trans-2,cis-9-octadecadienoyl-CoA 0.0 @@ -6534,7 +6534,7 @@ r_4608 propionyl-CoA transport ATP + H2O + propionyl-CoA --> ADP + H+ + phosphat r_4609 UDP transport UDP --> UDP 0.0 r_4609_REV UDP transport (reversible) UDP --> UDP 0.0 r_4610 UDP transport UDP --> UDP 0.0 -r_4610_REV UDP transport (reversible) UDP --> UDP 0.004927623923655561 +r_4610_REV UDP transport (reversible) UDP --> UDP 0.0 r_4611 UMP transport UMP --> UMP 0.0 r_4611_REV UMP transport (reversible) UMP --> UMP 0.0 r_4612 TRX1 disulphide transport TRX1 disulphide --> TRX1 disulphide 0.0 @@ -6760,7 +6760,7 @@ r_4721_REV ethyl-2-methylbutyrate esterase, c (reversible) 0.1481119020744172 pr r_4722 polyphosphate polymerase, c 0.6242867867867868 prot_P47075 + 2.0 ATP + H2O --> 2.0 ADP + H+ + polyphosphate 0.0 r_4723_EXP_1 polyphosphate phosphohydrolase, v 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4723_EXP_2 polyphosphate phosphohydrolase, v 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 -r_4724_EXP_1 polyphosphate phosphohydrolase, m 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 2.68171518573383 +r_4724_EXP_1 polyphosphate phosphohydrolase, m 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 2.6815533505623215 r_4724_EXP_2 polyphosphate phosphohydrolase, m 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4725_EXP_1 polyphosphate phosphohydrolase, n 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4725_EXP_2 polyphosphate phosphohydrolase, n 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 @@ -6793,7 +6793,7 @@ r_4742_REV ethyl-2-methylbutyrate transport (reversible) ethyl 2-methylbutyrate r_4743 ethyl-2-methylbutyrate exchange ethyl 2-methylbutyrate --> 0.0 r_4744 polyphosphate transport, v-c H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4744_REV polyphosphate transport, v-c (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 -r_4745 polyphosphate transport, c-m H+ + polyphosphate --> H+ + polyphosphate 2.68171518573383 +r_4745 polyphosphate transport, c-m H+ + polyphosphate --> H+ + polyphosphate 2.6815533505623215 r_4745_REV polyphosphate transport, c-m (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4746 polyphosphate transport, c-n H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4746_REV polyphosphate transport, c-n (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 @@ -6802,7 +6802,7 @@ r_4747_EXP_2 cytidine kinase (ATP) 1.7180232558139534 prot_Q12084 + ATP + cytidi r_4748_EXP_1 D-glyceraldehyde kinase 0.719388935146637 prot_P54838 + ATP + D-glyceraldehyde --> ADP + glyceraldehyde 3-phosphate + H+ 0.0 r_4748_EXP_2 D-glyceraldehyde kinase 0.7185562956795263 prot_P43550 + ATP + D-glyceraldehyde --> ADP + glyceraldehyde 3-phosphate + H+ 0.0 r_4749 adenosine phosphorylase 0.0027177938808373592 prot_Q05788 + adenosine + phosphate --> adenine + alpha-D-ribose 1-phosphate(2-) 0.0 -r_4749_REV adenosine phosphorylase (reversible) 0.21358516831181978 prot_Q05788 + adenine + alpha-D-ribose 1-phosphate(2-) --> adenosine + phosphate 1.9000000614987463e-05 +r_4749_REV adenosine phosphorylase (reversible) 0.21358516831181978 prot_Q05788 + adenine + alpha-D-ribose 1-phosphate(2-) --> adenosine + phosphate 1.9000000611411882e-05 r_4750 D-glucose 1-epimerase 0.532373366013072 prot_P04397 + alpha-D-Glucose --> beta-D-Glucose 0.0 r_4750_REV D-glucose 1-epimerase (reversible) 0.532373366013072 prot_P04397 + beta-D-Glucose --> alpha-D-Glucose 0.0 r_4751_EXP_1 D-phenylalanine N-acetyltransferase 2.211905943882526 prot_P39979 + acetyl-CoA + D-phenylalanine --> coenzyme A + N-acetyl-D-phenylalanine 0.0 @@ -6846,8 +6846,8 @@ r_4777 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dI r_4777_REV nucleoside diphosphate kinase (reversible) 0.3585421888053467 prot_P36010 + ADP + dITP --> ATP + dIDP 0.0 r_4778 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dUDP --> ADP + dUTP 0.0 r_4778_REV nucleoside diphosphate kinase (reversible) 0.3585421888053467 prot_P36010 + ADP + dUTP --> ATP + dUDP 0.0 -r_4779 heme a transport, cytoplasm-extracellular heme a --> heme a 0.0 -r_4779_REV heme a transport, cytoplasm-extracellular (reversible) heme a --> heme a 9.99999997475243e-08 +r_4779 heme a transport, cytoplasm-extracellular heme a --> heme a -9.99999997475243e-08 +r_4779_REV heme a transport, cytoplasm-extracellular (reversible) heme a --> heme a 0.0 r_4780 heme a exchange heme a --> -9.99999997475243e-08 r_4781 HET-P synthase (thiazole synthase) 0.11030922652440288 prot_P32318 + H2O + ADP-5-ethyl-4-methylthiazole-2-carboxylate --> 4-methyl-5-(2-phosphonooxyethyl)thiazole + AMP + carbon dioxide + H+ 1.20000004244503e-07 r_4782 adenylated thiazole synthase 0.0938740910644444 prot_P32318 + hydrogen sulfide + L-glycine + NAD --> H+ + 3.0 H2O + nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate 1.20000004244503e-07 @@ -6865,56 +6865,56 @@ r_4787_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + H+ + UDP + r_4787_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 r_4787_EXP_4 ribonucleotide reductase 0.9936907838070629 prot_P09938 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 usage_prot_O13525 usage_prot_O13525 prot_pool --> prot_O13525 0.0 -usage_prot_P00044 usage_prot_P00044 prot_pool --> prot_P00044 0.07955357273408556 -usage_prot_P00045 usage_prot_P00045 prot_pool --> prot_P00045 0.009336448681762803 -usage_prot_P00127 usage_prot_P00127 prot_pool --> prot_P00127 0.08828490503494621 -usage_prot_P00128 usage_prot_P00128 prot_pool --> prot_P00128 0.07451293051132823 -usage_prot_P00163 usage_prot_P00163 prot_pool --> prot_P00163 0.2233392718436351 +usage_prot_P00044 usage_prot_P00044 prot_pool --> prot_P00044 0.02363725507977324 +usage_prot_P00045 usage_prot_P00045 prot_pool --> prot_P00045 0.0 +usage_prot_P00127 usage_prot_P00127 prot_pool --> prot_P00127 0.01766236071015208 +usage_prot_P00128 usage_prot_P00128 prot_pool --> prot_P00128 0.014907126600415196 +usage_prot_P00163 usage_prot_P00163 prot_pool --> prot_P00163 0.04468146370530215 usage_prot_P00175 usage_prot_P00175 prot_pool --> prot_P00175 0.0 usage_prot_P00330 usage_prot_P00330 prot_pool --> prot_P00330 0.0 usage_prot_P00331 usage_prot_P00331 prot_pool --> prot_P00331 0.0 usage_prot_P00358 usage_prot_P00358 prot_pool --> prot_P00358 0.0 usage_prot_P00359 usage_prot_P00359 prot_pool --> prot_P00359 0.0 -usage_prot_P00360 usage_prot_P00360 prot_pool --> prot_P00360 0.24507565463616576 -usage_prot_P00401 usage_prot_P00401 prot_pool --> prot_P00401 0.12697656659492368 -usage_prot_P00410 usage_prot_P00410 prot_pool --> prot_P00410 0.06169154695597103 -usage_prot_P00420 usage_prot_P00420 prot_pool --> prot_P00420 0.06556360015343861 -usage_prot_P00424 usage_prot_P00424 prot_pool --> prot_P00424 0.03701449626580822 +usage_prot_P00360 usage_prot_P00360 prot_pool --> prot_P00360 0.24508163756541881 +usage_prot_P00401 usage_prot_P00401 prot_pool --> prot_P00401 0.053909127735251035 +usage_prot_P00410 usage_prot_P00410 prot_pool --> prot_P00410 0.026191742100291106 +usage_prot_P00420 usage_prot_P00420 prot_pool --> prot_P00420 0.027835659683020195 +usage_prot_P00424 usage_prot_P00424 prot_pool --> prot_P00424 0.015714861889557515 usage_prot_P00425 usage_prot_P00425 prot_pool --> prot_P00425 0.0 -usage_prot_P00427 usage_prot_P00427 prot_pool --> prot_P00427 0.03745072311794902 +usage_prot_P00427 usage_prot_P00427 prot_pool --> prot_P00427 0.015900066212876686 usage_prot_P00431 usage_prot_P00431 prot_pool --> prot_P00431 0.0 usage_prot_P00445 usage_prot_P00445 prot_pool --> prot_P00445 0.0 usage_prot_P00447 usage_prot_P00447 prot_pool --> prot_P00447 0.0 usage_prot_P00498 usage_prot_P00498 prot_pool --> prot_P00498 0.0069351225554408645 -usage_prot_P00549 usage_prot_P00549 prot_pool --> prot_P00549 0.10286249996428704 -usage_prot_P00560 usage_prot_P00560 prot_pool --> prot_P00560 0.04005909978758926 +usage_prot_P00549 usage_prot_P00549 prot_pool --> prot_P00549 0.10286886617611944 +usage_prot_P00560 usage_prot_P00560 prot_pool --> prot_P00560 0.04006007773360486 usage_prot_P00572 usage_prot_P00572 prot_pool --> prot_P00572 0.0 usage_prot_P00635 usage_prot_P00635 prot_pool --> prot_P00635 0.0 usage_prot_P00724 usage_prot_P00724 prot_pool --> prot_P00724 0.0 usage_prot_P00812 usage_prot_P00812 prot_pool --> prot_P00812 0.0 usage_prot_P00815 usage_prot_P00815 prot_pool --> prot_P00815 0.06105817814264418 -usage_prot_P00817 usage_prot_P00817 prot_pool --> prot_P00817 0.013488681103602214 -usage_prot_P00830 usage_prot_P00830 prot_pool --> prot_P00830 3.5927296018561874 -usage_prot_P00854 usage_prot_P00854 prot_pool --> prot_P00854 0.6359871438747138 -usage_prot_P00856 usage_prot_P00856 prot_pool --> prot_P00856 0.1272455119295709 -usage_prot_P00890 usage_prot_P00890 prot_pool --> prot_P00890 0.09277231868874844 -usage_prot_P00899 usage_prot_P00899 prot_pool --> prot_P00899 0.0005100871549317815 -usage_prot_P00912 usage_prot_P00912 prot_pool --> prot_P00912 0.00043389037023227635 -usage_prot_P00924 usage_prot_P00924 prot_pool --> prot_P00924 0.09283752408186827 +usage_prot_P00817 usage_prot_P00817 prot_pool --> prot_P00817 0.013479768558410809 +usage_prot_P00830 usage_prot_P00830 prot_pool --> prot_P00830 0.18918384916137962 +usage_prot_P00854 usage_prot_P00854 prot_pool --> prot_P00854 0.033489438179040196 +usage_prot_P00856 usage_prot_P00856 prot_pool --> prot_P00856 0.006700419570376027 +usage_prot_P00890 usage_prot_P00890 prot_pool --> prot_P00890 0.092782544264763 +usage_prot_P00899 usage_prot_P00899 prot_pool --> prot_P00899 0.0005100871549317877 +usage_prot_P00912 usage_prot_P00912 prot_pool --> prot_P00912 0.0004338903702322816 +usage_prot_P00924 usage_prot_P00924 prot_pool --> prot_P00924 0.09284303571868749 usage_prot_P00925 usage_prot_P00925 prot_pool --> prot_P00925 0.0 usage_prot_P00927 usage_prot_P00927 prot_pool --> prot_P00927 0.0 -usage_prot_P00931 usage_prot_P00931 prot_pool --> prot_P00931 0.0019270367106957221 -usage_prot_P00937 usage_prot_P00937 prot_pool --> prot_P00937 0.007400977766554495 -usage_prot_P00942 usage_prot_P00942 prot_pool --> prot_P00942 0.000707951255558805 -usage_prot_P00950 usage_prot_P00950 prot_pool --> prot_P00950 0.02186176766143539 +usage_prot_P00931 usage_prot_P00931 prot_pool --> prot_P00931 0.0019270367106957453 +usage_prot_P00937 usage_prot_P00937 prot_pool --> prot_P00937 0.007400977766554585 +usage_prot_P00942 usage_prot_P00942 prot_pool --> prot_P00942 0.0007079866345156479 +usage_prot_P00950 usage_prot_P00950 prot_pool --> prot_P00950 0.021863065564678368 usage_prot_P00958 usage_prot_P00958 prot_pool --> prot_P00958 0.007758377702723959 -usage_prot_P03962 usage_prot_P03962 prot_pool --> prot_P03962 0.00015285215150588152 +usage_prot_P03962 usage_prot_P03962 prot_pool --> prot_P03962 0.0001528521515060033 usage_prot_P03965 usage_prot_P03965 prot_pool --> prot_P03965 0.0 -usage_prot_P04037 usage_prot_P04037 prot_pool --> prot_P04037 0.037020974882424174 -usage_prot_P04039 usage_prot_P04039 prot_pool --> prot_P04039 0.019235012732762766 -usage_prot_P04046 usage_prot_P04046 prot_pool --> prot_P04046 0.0029018122709126393 +usage_prot_P04037 usage_prot_P04037 prot_pool --> prot_P04037 0.01571761244881473 +usage_prot_P04039 usage_prot_P04039 prot_pool --> prot_P04039 0.008166410434672625 +usage_prot_P04046 usage_prot_P04046 prot_pool --> prot_P04046 0.002901812270910534 usage_prot_P04076 usage_prot_P04076 prot_pool --> prot_P04076 9.576474603701102e-05 -usage_prot_P04161 usage_prot_P04161 prot_pool --> prot_P04161 0.0016740252577024293 +usage_prot_P04161 usage_prot_P04161 prot_pool --> prot_P04161 0.001674025257701215 usage_prot_P04173 usage_prot_P04173 prot_pool --> prot_P04173 0.002406504749325647 usage_prot_P04385 usage_prot_P04385 prot_pool --> prot_P04385 0.0 usage_prot_P04397 usage_prot_P04397 prot_pool --> prot_P04397 0.0 @@ -6929,17 +6929,17 @@ usage_prot_P05030 usage_prot_P05030 prot_pool --> prot_P05030 0.0 usage_prot_P05150 usage_prot_P05150 prot_pool --> prot_P05150 6.007467226861394e-05 usage_prot_P05316 usage_prot_P05316 prot_pool --> prot_P05316 0.0 usage_prot_P05373 usage_prot_P05373 prot_pool --> prot_P05373 0.0 -usage_prot_P05374 usage_prot_P05374 prot_pool --> prot_P05374 0.5859492729997433 -usage_prot_P05375 usage_prot_P05375 prot_pool --> prot_P05375 0.008496269931150218 -usage_prot_P05626 usage_prot_P05626 prot_pool --> prot_P05626 0.5884722447103565 -usage_prot_P05694 usage_prot_P05694 prot_pool --> prot_P05694 0.538116896081454 -usage_prot_P06106 usage_prot_P06106 prot_pool --> prot_P06106 0.0016681143322867327 -usage_prot_P06115 usage_prot_P06115 prot_pool --> prot_P06115 6.022168432065839e-11 -usage_prot_P06168 usage_prot_P06168 prot_pool --> prot_P06168 0.06349501004239205 -usage_prot_P06169 usage_prot_P06169 prot_pool --> prot_P06169 0.011210757588956108 +usage_prot_P05374 usage_prot_P05374 prot_pool --> prot_P05374 0.5845578504477592 +usage_prot_P05375 usage_prot_P05375 prot_pool --> prot_P05375 0.008476094291150829 +usage_prot_P05626 usage_prot_P05626 prot_pool --> prot_P05626 0.030987426474128228 +usage_prot_P05694 usage_prot_P05694 prot_pool --> prot_P05694 0.5375199865456393 +usage_prot_P06106 usage_prot_P06106 prot_pool --> prot_P06106 0.0016681143322862322 +usage_prot_P06115 usage_prot_P06115 prot_pool --> prot_P06115 6.022168430932536e-11 +usage_prot_P06168 usage_prot_P06168 prot_pool --> prot_P06168 0.06349501004238964 +usage_prot_P06169 usage_prot_P06169 prot_pool --> prot_P06169 0.01121075758898846 usage_prot_P06174 usage_prot_P06174 prot_pool --> prot_P06174 0.0 usage_prot_P06182 usage_prot_P06182 prot_pool --> prot_P06182 0.0 -usage_prot_P06197 usage_prot_P06197 prot_pool --> prot_P06197 0.0009015544945121599 +usage_prot_P06197 usage_prot_P06197 prot_pool --> prot_P06197 0.0009004387992834727 usage_prot_P06208 usage_prot_P06208 prot_pool --> prot_P06208 0.049955394439387076 usage_prot_P06633 usage_prot_P06633 prot_pool --> prot_P06633 3.951695237200766e-05 usage_prot_P06700 usage_prot_P06700 prot_pool --> prot_P06700 0.0 @@ -6949,31 +6949,31 @@ usage_prot_P06775 usage_prot_P06775 prot_pool --> prot_P06775 0.0002071093245123 usage_prot_P06776 usage_prot_P06776 prot_pool --> prot_P06776 0.0 usage_prot_P06780 usage_prot_P06780 prot_pool --> prot_P06780 0.0914294990677141 usage_prot_P06785 usage_prot_P06785 prot_pool --> prot_P06785 7.30145820791087e-05 -usage_prot_P07143 usage_prot_P07143 prot_pool --> prot_P07143 0.17422161679116258 -usage_prot_P07149 usage_prot_P07149 prot_pool --> prot_P07149 0.473465748974353 -usage_prot_P07170 usage_prot_P07170 prot_pool --> prot_P07170 0.002447998252029688 +usage_prot_P07143 usage_prot_P07143 prot_pool --> prot_P07143 0.03485493967573907 +usage_prot_P07149 usage_prot_P07149 prot_pool --> prot_P07149 0.4734657489744187 +usage_prot_P07170 usage_prot_P07170 prot_pool --> prot_P07170 0.0024478094838066055 usage_prot_P07172 usage_prot_P07172 prot_pool --> prot_P07172 3.193370984930483e-05 usage_prot_P07236 usage_prot_P07236 prot_pool --> prot_P07236 0.0 -usage_prot_P07244 usage_prot_P07244 prot_pool --> prot_P07244 0.06995023953389135 -usage_prot_P07245 usage_prot_P07245 prot_pool --> prot_P07245 0.03482319641922391 +usage_prot_P07244 usage_prot_P07244 prot_pool --> prot_P07244 0.06995023953384061 +usage_prot_P07245 usage_prot_P07245 prot_pool --> prot_P07245 0.03482319641936979 usage_prot_P07246 usage_prot_P07246 prot_pool --> prot_P07246 0.0 usage_prot_P07250 usage_prot_P07250 prot_pool --> prot_P07250 0.0 -usage_prot_P07251 usage_prot_P07251 prot_pool --> prot_P07251 3.84280571788129 -usage_prot_P07255 usage_prot_P07255 prot_pool --> prot_P07255 0.015036869165625591 -usage_prot_P07256 usage_prot_P07256 prot_pool --> prot_P07256 0.2569608976122894 -usage_prot_P07257 usage_prot_P07257 prot_pool --> prot_P07257 0.2070809750248915 +usage_prot_P07251 usage_prot_P07251 prot_pool --> prot_P07251 0.2023522106736164 +usage_prot_P07255 usage_prot_P07255 prot_pool --> prot_P07255 0.006384048035997023 +usage_prot_P07256 usage_prot_P07256 prot_pool --> prot_P07256 0.05140783761659145 +usage_prot_P07257 usage_prot_P07257 prot_pool --> prot_P07257 0.041428813630731635 usage_prot_P07258 usage_prot_P07258 prot_pool --> prot_P07258 0.0 -usage_prot_P07259 usage_prot_P07259 prot_pool --> prot_P07259 0.0020794197235068515 -usage_prot_P07262 usage_prot_P07262 prot_pool --> prot_P07262 0.2932549991937032 +usage_prot_P07259 usage_prot_P07259 prot_pool --> prot_P07259 0.0020794197235083395 +usage_prot_P07262 usage_prot_P07262 prot_pool --> prot_P07262 0.2932257132759945 usage_prot_P07263 usage_prot_P07263 prot_pool --> prot_P07263 0.0034792344478061566 usage_prot_P07264 usage_prot_P07264 prot_pool --> prot_P07264 0.055714728184709066 usage_prot_P07275 usage_prot_P07275 prot_pool --> prot_P07275 0.8057981178568774 -usage_prot_P07277 usage_prot_P07277 prot_pool --> prot_P07277 0.010450762435379471 +usage_prot_P07277 usage_prot_P07277 prot_pool --> prot_P07277 0.0104507624354398 usage_prot_P07283 usage_prot_P07283 prot_pool --> prot_P07283 0.028082351315826468 usage_prot_P07284 usage_prot_P07284 prot_pool --> prot_P07284 0.10089849414928333 -usage_prot_P07285 usage_prot_P07285 prot_pool --> prot_P07285 0.01275378408168489 +usage_prot_P07285 usage_prot_P07285 prot_pool --> prot_P07285 0.012753784081685043 usage_prot_P07286 usage_prot_P07286 prot_pool --> prot_P07286 0.0 -usage_prot_P07342 usage_prot_P07342 prot_pool --> prot_P07342 0.006561142598005734 +usage_prot_P07342 usage_prot_P07342 prot_pool --> prot_P07342 0.006561142598005444 usage_prot_P07347 usage_prot_P07347 prot_pool --> prot_P07347 0.0 usage_prot_P07702 usage_prot_P07702 prot_pool --> prot_P07702 0.034086674982829246 usage_prot_P07806 usage_prot_P07806 prot_pool --> prot_P07806 0.02198211901399119 @@ -6981,31 +6981,31 @@ usage_prot_P07807 usage_prot_P07807 prot_pool --> prot_P07807 1.1324891177556679 usage_prot_P07991 usage_prot_P07991 prot_pool --> prot_P07991 0.0 usage_prot_P08004 usage_prot_P08004 prot_pool --> prot_P08004 0.0 usage_prot_P08019 usage_prot_P08019 prot_pool --> prot_P08019 0.0 -usage_prot_P08067 usage_prot_P08067 prot_pool --> prot_P08067 0.11953275807738993 -usage_prot_P08417 usage_prot_P08417 prot_pool --> prot_P08417 0.011283276843064278 +usage_prot_P08067 usage_prot_P08067 prot_pool --> prot_P08067 0.02391383542867841 +usage_prot_P08417 usage_prot_P08417 prot_pool --> prot_P08417 0.011284667414753646 usage_prot_P08425 usage_prot_P08425 prot_pool --> prot_P08425 0.0 usage_prot_P08431 usage_prot_P08431 prot_pool --> prot_P08431 0.0 usage_prot_P08432 usage_prot_P08432 prot_pool --> prot_P08432 0.0 -usage_prot_P08456 usage_prot_P08456 prot_pool --> prot_P08456 0.07255715073851152 -usage_prot_P08465 usage_prot_P08465 prot_pool --> prot_P08465 0.011693579340053665 -usage_prot_P08524 usage_prot_P08524 prot_pool --> prot_P08524 0.15079889876857905 -usage_prot_P08525 usage_prot_P08525 prot_pool --> prot_P08525 0.056146887220173525 -usage_prot_P08536 usage_prot_P08536 prot_pool --> prot_P08536 0.007836587107454131 -usage_prot_P08566 usage_prot_P08566 prot_pool --> prot_P08566 0.06848582652332273 +usage_prot_P08456 usage_prot_P08456 prot_pool --> prot_P08456 0.0721365347987871 +usage_prot_P08465 usage_prot_P08465 prot_pool --> prot_P08465 0.011693579340050157 +usage_prot_P08524 usage_prot_P08524 prot_pool --> prot_P08524 0.15079889876944946 +usage_prot_P08525 usage_prot_P08525 prot_pool --> prot_P08525 0.011232798794339634 +usage_prot_P08536 usage_prot_P08536 prot_pool --> prot_P08536 0.007836587107451784 +usage_prot_P08566 usage_prot_P08566 prot_pool --> prot_P08566 0.06848582652332286 usage_prot_P08678 usage_prot_P08678 prot_pool --> prot_P08678 0.0 usage_prot_P08679 usage_prot_P08679 prot_pool --> prot_P08679 0.0 usage_prot_P09201 usage_prot_P09201 prot_pool --> prot_P09201 0.0 usage_prot_P09368 usage_prot_P09368 prot_pool --> prot_P09368 0.02982920763816391 usage_prot_P09436 usage_prot_P09436 prot_pool --> prot_P09436 0.01128077029308413 -usage_prot_P09440 usage_prot_P09440 prot_pool --> prot_P09440 -1.517687617645931e-12 -usage_prot_P09457 usage_prot_P09457 prot_pool --> prot_P09457 0.4986223134938561 -usage_prot_P09624 usage_prot_P09624 prot_pool --> prot_P09624 0.30613862870694203 +usage_prot_P09440 usage_prot_P09440 prot_pool --> prot_P09440 0.0 +usage_prot_P09457 usage_prot_P09457 prot_pool --> prot_P09457 0.02625616147003756 +usage_prot_P09624 usage_prot_P09624 prot_pool --> prot_P09624 0.306170143201428 usage_prot_P09938 usage_prot_P09938 prot_pool --> prot_P09938 0.0 usage_prot_P09950 usage_prot_P09950 prot_pool --> prot_P09950 0.0 usage_prot_P0C5R9 usage_prot_P0C5R9 prot_pool --> prot_P0C5R9 0.0 -usage_prot_P0CD90 usage_prot_P0CD90 prot_pool --> prot_P0CD90 1.8697398088153476 +usage_prot_P0CD90 usage_prot_P0CD90 prot_pool --> prot_P0CD90 1.8697785849710469 usage_prot_P0CD91 usage_prot_P0CD91 prot_pool --> prot_P0CD91 0.0 -usage_prot_P0CD98 usage_prot_P0CD98 prot_pool --> prot_P0CD98 0.0011750670962021668 +usage_prot_P0CD98 usage_prot_P0CD98 prot_pool --> prot_P0CD98 0.0013103500245820608 usage_prot_P0CD99 usage_prot_P0CD99 prot_pool --> prot_P0CD99 0.0 usage_prot_P0CE00 usage_prot_P0CE00 prot_pool --> prot_P0CE00 0.0 usage_prot_P0CH63 usage_prot_P0CH63 prot_pool --> prot_P0CH63 0.0 @@ -7021,43 +7021,43 @@ usage_prot_P0CX78 usage_prot_P0CX78 prot_pool --> prot_P0CX78 0.0 usage_prot_P0CX79 usage_prot_P0CX79 prot_pool --> prot_P0CX79 0.0 usage_prot_P0CZ17 usage_prot_P0CZ17 prot_pool --> prot_P0CZ17 0.0 usage_prot_P10127 usage_prot_P10127 prot_pool --> prot_P10127 0.0 -usage_prot_P10174 usage_prot_P10174 prot_pool --> prot_P10174 0.014969923460594083 +usage_prot_P10174 usage_prot_P10174 prot_pool --> prot_P10174 0.00635562559033913 usage_prot_P10356 usage_prot_P10356 prot_pool --> prot_P10356 0.0 usage_prot_P10566 usage_prot_P10566 prot_pool --> prot_P10566 0.0 -usage_prot_P10614 usage_prot_P10614 prot_pool --> prot_P10614 0.00932999040944742 +usage_prot_P10614 usage_prot_P10614 prot_pool --> prot_P10614 0.009329990409501273 usage_prot_P10659 usage_prot_P10659 prot_pool --> prot_P10659 0.0 -usage_prot_P10869 usage_prot_P10869 prot_pool --> prot_P10869 0.0025202403312001467 +usage_prot_P10869 usage_prot_P10869 prot_pool --> prot_P10869 0.0025202403311998926 usage_prot_P10963 usage_prot_P10963 prot_pool --> prot_P10963 0.0 -usage_prot_P11154 usage_prot_P11154 prot_pool --> prot_P11154 0.1467746878216315 +usage_prot_P11154 usage_prot_P11154 prot_pool --> prot_P11154 0.14677468782162612 usage_prot_P11325 usage_prot_P11325 prot_pool --> prot_P11325 0.0 usage_prot_P11353 usage_prot_P11353 prot_pool --> prot_P11353 0.0 -usage_prot_P11412 usage_prot_P11412 prot_pool --> prot_P11412 0.007922479539349941 +usage_prot_P11412 usage_prot_P11412 prot_pool --> prot_P11412 0.007920240263095733 usage_prot_P11491 usage_prot_P11491 prot_pool --> prot_P11491 3.990668894998343e-06 -usage_prot_P11986 usage_prot_P11986 prot_pool --> prot_P11986 0.0014777301144891252 -usage_prot_P12683 usage_prot_P12683 prot_pool --> prot_P12683 0.034166586572754114 +usage_prot_P11986 usage_prot_P11986 prot_pool --> prot_P11986 0.001475901388163653 +usage_prot_P12683 usage_prot_P12683 prot_pool --> prot_P12683 0.034166586572951345 usage_prot_P12684 usage_prot_P12684 prot_pool --> prot_P12684 0.0 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usage_prot_P32288 prot_pool --> prot_P32288 0.0030614079635081764 +usage_prot_P32316 usage_prot_P32316 prot_pool --> prot_P32316 0.0 usage_prot_P32318 usage_prot_P32318 prot_pool --> prot_P32318 2.4501998977318376e-08 usage_prot_P32327 usage_prot_P32327 prot_pool --> prot_P32327 0.0 -usage_prot_P32331 usage_prot_P32331 prot_pool --> prot_P32331 0.00015754712507334772 -usage_prot_P32332 usage_prot_P32332 prot_pool --> prot_P32332 0.02284632463430561 -usage_prot_P32340 usage_prot_P32340 prot_pool --> prot_P32340 0.08753957313289004 +usage_prot_P32331 usage_prot_P32331 prot_pool --> prot_P32331 0.000157547123467404 +usage_prot_P32332 usage_prot_P32332 prot_pool --> prot_P32332 0.0228463246344587 +usage_prot_P32340 usage_prot_P32340 prot_pool --> prot_P32340 0.08754887437316758 usage_prot_P32347 usage_prot_P32347 prot_pool --> prot_P32347 0.0 usage_prot_P32352 usage_prot_P32352 prot_pool --> prot_P32352 0.0 usage_prot_P32353 usage_prot_P32353 prot_pool --> prot_P32353 0.0 @@ -7251,23 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prot_P32476 0.5943444739030734 usage_prot_P32477 usage_prot_P32477 prot_pool --> prot_P32477 2.13319158216116e-10 usage_prot_P32486 usage_prot_P32486 prot_pool --> prot_P32486 0.0 usage_prot_P32487 usage_prot_P32487 prot_pool --> prot_P32487 0.0 @@ -7276,47 +7276,47 @@ usage_prot_P32563 usage_prot_P32563 prot_pool --> prot_P32563 0.0 usage_prot_P32567 usage_prot_P32567 prot_pool --> prot_P32567 0.0 usage_prot_P32573 usage_prot_P32573 prot_pool --> prot_P32573 0.0 usage_prot_P32579 usage_prot_P32579 prot_pool --> prot_P32579 0.0 -usage_prot_P32582 usage_prot_P32582 prot_pool --> prot_P32582 0.002732375312816758 +usage_prot_P32582 usage_prot_P32582 prot_pool --> prot_P32582 0.002732375312814169 usage_prot_P32603 usage_prot_P32603 prot_pool --> prot_P32603 0.0 usage_prot_P32604 usage_prot_P32604 prot_pool --> prot_P32604 0.0 usage_prot_P32610 usage_prot_P32610 prot_pool --> prot_P32610 0.0 -usage_prot_P32614 usage_prot_P32614 prot_pool --> prot_P32614 0.0619319371041115 +usage_prot_P32614 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usage_prot_P33412 usage_prot_P33412 prot_pool --> prot_P33412 0.0 usage_prot_P33413 usage_prot_P33413 prot_pool --> prot_P33413 0.0 -usage_prot_P33421 usage_prot_P33421 prot_pool --> prot_P33421 0.019468812887509478 +usage_prot_P33421 usage_prot_P33421 prot_pool --> prot_P33421 0.019471111171806624 usage_prot_P33550 usage_prot_P33550 prot_pool --> prot_P33550 0.0 usage_prot_P33734 usage_prot_P33734 prot_pool --> prot_P33734 0.020544584974038976 usage_prot_P33751 usage_prot_P33751 prot_pool --> prot_P33751 0.0 @@ -7335,20 +7335,20 @@ usage_prot_P35731 usage_prot_P35731 prot_pool --> prot_P35731 0.0 usage_prot_P35842 usage_prot_P35842 prot_pool --> prot_P35842 0.0 usage_prot_P36001 usage_prot_P36001 prot_pool --> prot_P36001 0.0 usage_prot_P36007 usage_prot_P36007 prot_pool --> prot_P36007 0.0 -usage_prot_P36010 usage_prot_P36010 prot_pool --> prot_P36010 0.00361589579221923 -usage_prot_P36013 usage_prot_P36013 prot_pool --> prot_P36013 0.0026885123452822265 +usage_prot_P36010 usage_prot_P36010 prot_pool --> prot_P36010 0.0036202615769299028 +usage_prot_P36013 usage_prot_P36013 prot_pool --> prot_P36013 0.0026885123452794193 usage_prot_P36014 usage_prot_P36014 prot_pool --> prot_P36014 0.0 -usage_prot_P36024 usage_prot_P36024 prot_pool --> prot_P36024 0.00011370517609417496 +usage_prot_P36024 usage_prot_P36024 prot_pool --> prot_P36024 0.00011370517607277697 usage_prot_P36029 usage_prot_P36029 prot_pool --> prot_P36029 0.0 usage_prot_P36033 usage_prot_P36033 prot_pool --> prot_P36033 0.0 usage_prot_P36035 usage_prot_P36035 prot_pool --> prot_P36035 0.0 usage_prot_P36051 usage_prot_P36051 prot_pool --> prot_P36051 0.0 usage_prot_P36060 usage_prot_P36060 prot_pool --> prot_P36060 0.0 usage_prot_P36062 usage_prot_P36062 prot_pool --> prot_P36062 0.0 -usage_prot_P36076 usage_prot_P36076 prot_pool --> prot_P36076 0.000118728164762505 +usage_prot_P36076 usage_prot_P36076 prot_pool --> prot_P36076 0.00011872816474016172 usage_prot_P36088 usage_prot_P36088 prot_pool --> prot_P36088 0.0 usage_prot_P36107 usage_prot_P36107 prot_pool --> prot_P36107 0.0 -usage_prot_P36126 usage_prot_P36126 prot_pool --> prot_P36126 3.833185117764835e-05 +usage_prot_P36126 usage_prot_P36126 prot_pool --> prot_P36126 4.274491413745264e-05 usage_prot_P36136 usage_prot_P36136 prot_pool --> prot_P36136 0.0 usage_prot_P36143 usage_prot_P36143 prot_pool --> prot_P36143 0.0 usage_prot_P36148 usage_prot_P36148 prot_pool --> prot_P36148 0.08449181759647247 @@ -7357,32 +7357,32 @@ usage_prot_P36156 usage_prot_P36156 prot_pool --> prot_P36156 0.0 usage_prot_P36165 usage_prot_P36165 prot_pool --> prot_P36165 0.0 usage_prot_P36421 usage_prot_P36421 prot_pool --> prot_P36421 0.03270283567694129 usage_prot_P36973 usage_prot_P36973 prot_pool --> prot_P36973 0.0 -usage_prot_P37012 usage_prot_P37012 prot_pool --> prot_P37012 0.012061328936742634 +usage_prot_P37012 usage_prot_P37012 prot_pool --> prot_P37012 0.012061328936742343 usage_prot_P37020 usage_prot_P37020 prot_pool --> prot_P37020 0.0 usage_prot_P37254 usage_prot_P37254 prot_pool --> prot_P37254 0.009172695793144503 -usage_prot_P37291 usage_prot_P37291 prot_pool --> prot_P37291 0.0010604907283445837 +usage_prot_P37291 usage_prot_P37291 prot_pool --> prot_P37291 0.0010599322533794543 usage_prot_P37292 usage_prot_P37292 prot_pool --> prot_P37292 0.0 usage_prot_P37296 usage_prot_P37296 prot_pool --> prot_P37296 0.0 usage_prot_P37297 usage_prot_P37297 prot_pool --> prot_P37297 0.0 usage_prot_P37298 usage_prot_P37298 prot_pool --> prot_P37298 0.0 -usage_prot_P37299 usage_prot_P37299 prot_pool --> prot_P37299 0.04396083844036001 +usage_prot_P37299 usage_prot_P37299 prot_pool --> prot_P37299 0.008794846472871114 usage_prot_P37303 usage_prot_P37303 prot_pool --> prot_P37303 0.0 -usage_prot_P38009 usage_prot_P38009 prot_pool --> prot_P38009 0.07840419894304484 +usage_prot_P38009 usage_prot_P38009 prot_pool --> prot_P38009 0.07840419894301354 usage_prot_P38013 usage_prot_P38013 prot_pool --> prot_P38013 0.0 usage_prot_P38063 usage_prot_P38063 prot_pool --> prot_P38063 0.0 -usage_prot_P38066 usage_prot_P38066 prot_pool --> prot_P38066 2.4647633032538165e-06 +usage_prot_P38066 usage_prot_P38066 prot_pool --> prot_P38066 2.464763303253681e-06 usage_prot_P38067 usage_prot_P38067 prot_pool --> prot_P38067 0.0 usage_prot_P38071 usage_prot_P38071 prot_pool --> prot_P38071 0.0 usage_prot_P38074 usage_prot_P38074 prot_pool --> prot_P38074 0.0 usage_prot_P38075 usage_prot_P38075 prot_pool --> prot_P38075 0.0 -usage_prot_P38077 usage_prot_P38077 prot_pool --> prot_P38077 0.75077474755972 +usage_prot_P38077 usage_prot_P38077 prot_pool --> prot_P38077 0.03953385652043746 usage_prot_P38084 usage_prot_P38084 prot_pool --> prot_P38084 0.0 usage_prot_P38085 usage_prot_P38085 prot_pool --> prot_P38085 0.0 usage_prot_P38088 usage_prot_P38088 prot_pool --> prot_P38088 0.0 usage_prot_P38090 usage_prot_P38090 prot_pool --> prot_P38090 0.0 usage_prot_P38113 usage_prot_P38113 prot_pool --> prot_P38113 0.0 usage_prot_P38115 usage_prot_P38115 prot_pool --> prot_P38115 0.0 -usage_prot_P38122 usage_prot_P38122 prot_pool --> prot_P38122 0.00023230985568168825 +usage_prot_P38122 usage_prot_P38122 prot_pool --> prot_P38122 0.0002323098556379702 usage_prot_P38125 usage_prot_P38125 prot_pool --> prot_P38125 0.0 usage_prot_P38127 usage_prot_P38127 prot_pool --> prot_P38127 0.0 usage_prot_P38130 usage_prot_P38130 prot_pool --> prot_P38130 0.0 @@ -7392,17 +7392,17 @@ usage_prot_P38138 usage_prot_P38138 prot_pool --> prot_P38138 0.0 usage_prot_P38139 usage_prot_P38139 prot_pool --> prot_P38139 0.0 usage_prot_P38142 usage_prot_P38142 prot_pool --> prot_P38142 0.0 usage_prot_P38143 usage_prot_P38143 prot_pool --> prot_P38143 0.0 -usage_prot_P38145 usage_prot_P38145 prot_pool --> prot_P38145 0.005450686484172771 +usage_prot_P38145 usage_prot_P38145 prot_pool --> prot_P38145 0.005450686484172471 usage_prot_P38149 usage_prot_P38149 prot_pool --> prot_P38149 0.0 -usage_prot_P38152 usage_prot_P38152 prot_pool --> prot_P38152 0.07669873112333249 +usage_prot_P38152 usage_prot_P38152 prot_pool --> prot_P38152 0.07669873112333411 usage_prot_P38156 usage_prot_P38156 prot_pool --> prot_P38156 0.0 usage_prot_P38158 usage_prot_P38158 prot_pool --> prot_P38158 0.0 -usage_prot_P38169 usage_prot_P38169 prot_pool --> prot_P38169 0.00435473492934048 +usage_prot_P38169 usage_prot_P38169 prot_pool --> prot_P38169 0.004354734929340862 usage_prot_P38174 usage_prot_P38174 prot_pool --> prot_P38174 0.0 usage_prot_P38196 usage_prot_P38196 prot_pool --> prot_P38196 0.0 usage_prot_P38211 usage_prot_P38211 prot_pool --> prot_P38211 0.0 usage_prot_P38218 usage_prot_P38218 prot_pool --> prot_P38218 0.0 -usage_prot_P38221 usage_prot_P38221 prot_pool --> prot_P38221 0.00990160595636581 +usage_prot_P38221 usage_prot_P38221 prot_pool --> prot_P38221 0.009850506766660615 usage_prot_P38225 usage_prot_P38225 prot_pool --> prot_P38225 0.0 usage_prot_P38226 usage_prot_P38226 prot_pool --> prot_P38226 0.0 usage_prot_P38230 usage_prot_P38230 prot_pool --> prot_P38230 0.0 @@ -7417,16 +7417,16 @@ usage_prot_P38329 usage_prot_P38329 prot_pool --> prot_P38329 0.0 usage_prot_P38331 usage_prot_P38331 prot_pool --> prot_P38331 0.0 usage_prot_P38342 usage_prot_P38342 prot_pool --> prot_P38342 0.0 usage_prot_P38358 usage_prot_P38358 prot_pool --> prot_P38358 0.0 -usage_prot_P38359 usage_prot_P38359 prot_pool --> prot_P38359 0.03374014317424362 +usage_prot_P38359 usage_prot_P38359 prot_pool --> prot_P38359 0.03374014317423497 usage_prot_P38360 usage_prot_P38360 prot_pool --> prot_P38360 0.0 -usage_prot_P38361 usage_prot_P38361 prot_pool --> prot_P38361 0.04425262594593667 +usage_prot_P38361 usage_prot_P38361 prot_pool --> prot_P38361 0.04420252886300534 usage_prot_P38426 usage_prot_P38426 prot_pool --> prot_P38426 0.028198896311191803 usage_prot_P38427 usage_prot_P38427 prot_pool --> prot_P38427 0.0 -usage_prot_P38604 usage_prot_P38604 prot_pool --> prot_P38604 0.09015052802335533 -usage_prot_P38620 usage_prot_P38620 prot_pool --> prot_P38620 0.0039778596661124025 +usage_prot_P38604 usage_prot_P38604 prot_pool --> prot_P38604 0.09015052802387569 +usage_prot_P38620 usage_prot_P38620 prot_pool --> prot_P38620 0.003977859666112544 usage_prot_P38625 usage_prot_P38625 prot_pool --> prot_P38625 4.7056806217261684e-05 -usage_prot_P38626 usage_prot_P38626 prot_pool --> prot_P38626 8.798620132804441e-05 -usage_prot_P38627 usage_prot_P38627 prot_pool --> prot_P38627 0.0027680768629305456 +usage_prot_P38626 usage_prot_P38626 prot_pool --> prot_P38626 8.798620132855227e-05 +usage_prot_P38627 usage_prot_P38627 prot_pool --> prot_P38627 0.0027680768629353464 usage_prot_P38628 usage_prot_P38628 prot_pool --> prot_P38628 0.0010068169057630475 usage_prot_P38631 usage_prot_P38631 prot_pool --> prot_P38631 0.0 usage_prot_P38635 usage_prot_P38635 prot_pool --> prot_P38635 4.185079666463251e-05 @@ -7434,8 +7434,8 @@ usage_prot_P38689 usage_prot_P38689 prot_pool --> prot_P38689 0.0 usage_prot_P38693 usage_prot_P38693 prot_pool --> prot_P38693 0.0 usage_prot_P38695 usage_prot_P38695 prot_pool --> prot_P38695 0.0 usage_prot_P38697 usage_prot_P38697 prot_pool --> prot_P38697 0.014250964064106399 -usage_prot_P38698 usage_prot_P38698 prot_pool --> prot_P38698 0.035253493823022924 -usage_prot_P38702 usage_prot_P38702 prot_pool --> prot_P38702 0.0038135142625862046 +usage_prot_P38698 usage_prot_P38698 prot_pool --> prot_P38698 0.035250426149960525 +usage_prot_P38702 usage_prot_P38702 prot_pool --> prot_P38702 0.0038135142626082304 usage_prot_P38703 usage_prot_P38703 prot_pool --> prot_P38703 0.0 usage_prot_P38705 usage_prot_P38705 prot_pool --> prot_P38705 0.004304725671790807 usage_prot_P38707 usage_prot_P38707 prot_pool --> prot_P38707 0.0327575744136394 @@ -7444,31 +7444,31 @@ usage_prot_P38709 usage_prot_P38709 prot_pool --> prot_P38709 0.0246308504566210 usage_prot_P38710 usage_prot_P38710 prot_pool --> prot_P38710 0.0 usage_prot_P38714 usage_prot_P38714 prot_pool 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usage_prot_P40004 prot_pool --> prot_P40004 0.0 -usage_prot_P40009 usage_prot_P40009 prot_pool --> prot_P40009 0.013847146539318367 +usage_prot_P40009 usage_prot_P40009 prot_pool --> prot_P40009 0.013847171132127323 usage_prot_P40011 usage_prot_P40011 prot_pool --> prot_P40011 0.0 usage_prot_P40012 usage_prot_P40012 prot_pool --> prot_P40012 0.0 usage_prot_P40015 usage_prot_P40015 prot_pool --> prot_P40015 0.0 usage_prot_P40017 usage_prot_P40017 prot_pool --> prot_P40017 0.0 usage_prot_P40025 usage_prot_P40025 prot_pool --> prot_P40025 0.0 usage_prot_P40029 usage_prot_P40029 prot_pool --> prot_P40029 0.0 -usage_prot_P40035 usage_prot_P40035 prot_pool --> prot_P40035 0.022899157793826883 +usage_prot_P40035 usage_prot_P40035 prot_pool --> prot_P40035 0.022899157793307576 usage_prot_P40039 usage_prot_P40039 prot_pool --> prot_P40039 0.0 usage_prot_P40047 usage_prot_P40047 prot_pool --> prot_P40047 0.0 usage_prot_P40054 usage_prot_P40054 prot_pool --> prot_P40054 0.0 @@ -7539,12 +7539,12 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usage_prot_P40527 usage_prot_P40527 prot_pool --> prot_P40527 0.0 usage_prot_P40544 usage_prot_P40544 prot_pool --> prot_P40544 0.0 usage_prot_P40545 usage_prot_P40545 prot_pool --> prot_P40545 0.0021440906329501146 @@ -7565,7 +7565,7 @@ usage_prot_P40975 usage_prot_P40975 prot_pool --> prot_P40975 0.0 usage_prot_P40988 usage_prot_P40988 prot_pool --> prot_P40988 2.4101980169772022e-05 usage_prot_P40989 usage_prot_P40989 prot_pool --> prot_P40989 0.0 usage_prot_P41277 usage_prot_P41277 prot_pool --> prot_P41277 0.0 -usage_prot_P41338 usage_prot_P41338 prot_pool --> prot_P41338 0.0732789704114119 +usage_prot_P41338 usage_prot_P41338 prot_pool --> prot_P41338 0.07327897041183491 usage_prot_P41734 usage_prot_P41734 prot_pool --> prot_P41734 0.0 usage_prot_P41735 usage_prot_P41735 prot_pool --> prot_P41735 0.0 usage_prot_P41807 usage_prot_P41807 prot_pool --> prot_P41807 0.0 @@ -7576,7 +7576,7 @@ usage_prot_P41909 usage_prot_P41909 prot_pool --> prot_P41909 0.0 usage_prot_P41911 usage_prot_P41911 prot_pool --> prot_P41911 0.0 usage_prot_P41921 usage_prot_P41921 prot_pool --> prot_P41921 0.0 usage_prot_P41930 usage_prot_P41930 prot_pool --> prot_P41930 0.0 -usage_prot_P41939 usage_prot_P41939 prot_pool --> prot_P41939 0.03997454921144516 +usage_prot_P41939 usage_prot_P41939 prot_pool --> prot_P41939 0.03997949352004267 usage_prot_P41940 usage_prot_P41940 prot_pool --> prot_P41940 0.003938647076172651 usage_prot_P41948 usage_prot_P41948 prot_pool --> prot_P41948 0.0 usage_prot_P42222 usage_prot_P42222 prot_pool --> prot_P42222 0.0 @@ -7584,7 +7584,7 @@ usage_prot_P42826 usage_prot_P42826 prot_pool --> prot_P42826 0.0 usage_prot_P42833 usage_prot_P42833 prot_pool --> prot_P42833 0.0 usage_prot_P42837 usage_prot_P42837 prot_pool --> prot_P42837 0.0 usage_prot_P42884 usage_prot_P42884 prot_pool --> prot_P42884 0.0 -usage_prot_P42941 usage_prot_P42941 prot_pool --> prot_P42941 0.0005558672453791538 +usage_prot_P42941 usage_prot_P42941 prot_pool --> prot_P42941 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prot_pool --> prot_Q12233 0.28240110952284186 +usage_prot_Q12233 usage_prot_Q12233 prot_pool --> prot_Q12233 0.014870512069534292 usage_prot_Q12246 usage_prot_Q12246 prot_pool --> prot_Q12246 0.0 usage_prot_Q12251 usage_prot_Q12251 prot_pool --> prot_Q12251 0.0 usage_prot_Q12256 usage_prot_Q12256 prot_pool --> prot_Q12256 0.0 @@ -7971,19 +7971,19 @@ usage_prot_Q12305 usage_prot_Q12305 prot_pool --> prot_Q12305 0.0 usage_prot_Q12320 usage_prot_Q12320 prot_pool --> prot_Q12320 0.0 usage_prot_Q12325 usage_prot_Q12325 prot_pool --> prot_Q12325 0.0 usage_prot_Q12333 usage_prot_Q12333 prot_pool --> prot_Q12333 0.0 -usage_prot_Q12349 usage_prot_Q12349 prot_pool --> prot_Q12349 0.30878127663019195 +usage_prot_Q12349 usage_prot_Q12349 prot_pool --> prot_Q12349 0.01625962344388054 usage_prot_Q12358 usage_prot_Q12358 prot_pool --> prot_Q12358 0.0 -usage_prot_Q12359 usage_prot_Q12359 prot_pool --> prot_Q12359 0.3725383114499432 -usage_prot_Q12362 usage_prot_Q12362 prot_pool --> prot_Q12362 0.0188092025989496 +usage_prot_Q12359 usage_prot_Q12359 prot_pool --> prot_Q12359 0.37250705174992177 +usage_prot_Q12362 usage_prot_Q12362 prot_pool --> prot_Q12362 0.018809202598948565 usage_prot_Q12372 usage_prot_Q12372 prot_pool --> prot_Q12372 0.0 usage_prot_Q12375 usage_prot_Q12375 prot_pool --> prot_Q12375 0.026678809377455353 usage_prot_Q12382 usage_prot_Q12382 prot_pool --> prot_Q12382 0.0 -usage_prot_Q12412 usage_prot_Q12412 prot_pool --> prot_Q12412 0.013827859230847199 +usage_prot_Q12412 usage_prot_Q12412 prot_pool --> prot_Q12412 0.015419830698706354 usage_prot_Q12428 usage_prot_Q12428 prot_pool --> prot_Q12428 0.0 usage_prot_Q12436 usage_prot_Q12436 prot_pool --> prot_Q12436 0.0 usage_prot_Q12447 usage_prot_Q12447 prot_pool --> prot_Q12447 0.0 -usage_prot_Q12452 usage_prot_Q12452 prot_pool --> prot_Q12452 0.1114882803662891 -usage_prot_Q12455 usage_prot_Q12455 prot_pool --> prot_Q12455 5.622647751436958e-06 +usage_prot_Q12452 usage_prot_Q12452 prot_pool --> prot_Q12452 0.11148828036693262 +usage_prot_Q12455 usage_prot_Q12455 prot_pool --> prot_Q12455 5.6226477503788405e-06 usage_prot_Q12458 usage_prot_Q12458 prot_pool --> prot_Q12458 0.0 usage_prot_Q12471 usage_prot_Q12471 prot_pool --> prot_Q12471 0.0 usage_prot_Q12473 usage_prot_Q12473 prot_pool --> prot_Q12473 0.0 @@ -8002,10 +8002,10 @@ usage_prot_Q3E731 usage_prot_Q3E731 prot_pool --> prot_Q3E731 0.0 usage_prot_Q3E790 usage_prot_Q3E790 prot_pool --> prot_Q3E790 0.0 usage_prot_Q3E7B6 usage_prot_Q3E7B6 prot_pool --> prot_Q3E7B6 0.0 usage_prot_Q99190 usage_prot_Q99190 prot_pool --> prot_Q99190 0.009966365805277934 -usage_prot_Q99258 usage_prot_Q99258 prot_pool --> prot_Q99258 0.0005698989734288817 +usage_prot_Q99258 usage_prot_Q99258 prot_pool --> prot_Q99258 0.0005698989734288502 usage_prot_Q99271 usage_prot_Q99271 prot_pool --> prot_Q99271 0.0 usage_prot_Q99297 usage_prot_Q99297 prot_pool --> prot_Q99297 0.012854386194880702 usage_prot_Q99312 usage_prot_Q99312 prot_pool --> prot_Q99312 0.0 usage_prot_Q99321 usage_prot_Q99321 prot_pool --> prot_Q99321 0.0 -prot_pool_exchange prot_pool_exchange --> prot_pool 41.82509026933145 -usage_prot_standard usage_prot_standard prot_pool --> prot_standard 0.09157844356769211 +prot_pool_exchange prot_pool_exchange --> prot_pool 27.14128997661222 +usage_prot_standard usage_prot_standard prot_pool --> prot_standard 0.09157844356775338 diff --git a/results/modelSimulation/allFluxes_CN75.tsv b/results/modelSimulation/allFluxes_CN75.tsv index 0b4f3fc..c66013e 100644 --- a/results/modelSimulation/allFluxes_CN75.tsv +++ b/results/modelSimulation/allFluxes_CN75.tsv @@ -1,13 +1,13 @@ rxnID rxnName equation flux r_0001_EXP_1 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 3.143317927979973 prot_P32891 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 -r_0001_EXP_2 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 3.143317927979973 prot_P32891 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 +r_0001_EXP_2 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 3.143317927979973 prot_P32891 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.014524343371633077 r_0001_EXP_3 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 2.658626997881764 prot_P39976 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 -r_0001_EXP_4 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 2.658626997881764 prot_P39976 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 +r_0001_EXP_4 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 2.658626997881764 prot_P39976 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.021865665799795587 r_0002_EXP_1 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.6033121509724629 prot_P00045 + 2.853264009243212 prot_P46681 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 -r_0002_EXP_2 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 2.853264009243212 prot_P46681 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 +r_0002_EXP_2 (R)-lactate:ferricytochrome-c 2-oxidoreductase 0.5864625457346427 prot_P00044 + 2.853264009243212 prot_P46681 + (R)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.007112332800000001 r_0003 (R,R)-butanediol dehydrogenase 0.11954621771429885 prot_P39714 + (R,R)-2,3-butanediol + NAD --> (R)-acetoin + H+ + NADH 0.0 r_0003_REV (R,R)-butanediol dehydrogenase (reversible) 0.0770037037037037 prot_P39714 + (R)-acetoin + H+ + NADH --> (R,R)-2,3-butanediol + NAD 0.0 -r_0004_EXP_1 (S)-lactate:ferricytochrome-c 2-oxidoreductase 0.009357825567502987 prot_P00045 + 0.04893891875746714 prot_P00175 + (S)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.020355037763593847 +r_0004_EXP_1 (S)-lactate:ferricytochrome-c 2-oxidoreductase 0.009357825567502987 prot_P00045 + 0.04893891875746714 prot_P00175 + (S)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 r_0004_EXP_2 (S)-lactate:ferricytochrome-c 2-oxidoreductase 0.00909647550776583 prot_P00044 + 0.04893891875746714 prot_P00175 + (S)-lactate + 2.0 ferricytochrome c --> 2.0 ferrocytochrome c + pyruvate 0.0 r_0005_EXP_1 1,3-beta-glucan synthase 1.236971332463594 prot_P06780 + 11.479117473701436 prot_P38631 + UDP-D-glucose --> (1->3)-beta-D-glucan + H+ + UDP 0.0 r_0005_EXP_2 1,3-beta-glucan synthase 1.236971332463594 prot_P06780 + 11.593400545580307 prot_P40989 + UDP-D-glucose --> (1->3)-beta-D-glucan + H+ + UDP 0.0 @@ -21,22 +21,22 @@ r_0014 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase 188. r_0015 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH) 0.5311659867712155 prot_P33312 + 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + H+ + NADPH --> 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + NADP(+) 9.999999710998968e-05 r_0016_EXP_1 2-aceto-2-hydroxybutanoate synthase 0.08099546044098574 prot_P07342 + 0.03673476005188067 prot_P25605 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.0 r_0016_EXP_2 2-aceto-2-hydroxybutanoate synthase 0.04049773022049287 prot_P07342 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.0265490320174191 -r_0017 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 63.477512816721614 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + ATP --> (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + AMP + H+ 6.340000254510467e-06 +r_0017 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 63.477512816721614 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + ATP --> (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + AMP + H+ 6.340000254623224e-06 r_0018_EXP_1 2-aminoadipate transaminase 0.7210471896303212 prot_P10356 + 2-oxoadipic acid + L-glutamate --> 2-oxoglutarate + L-2-aminoadipate 0.0 r_0018_EXP_2 2-aminoadipate transaminase 1.219140625 prot_P53090 + 2-oxoadipic acid + L-glutamate --> 2-oxoglutarate + L-2-aminoadipate 0.0 r_0018_EXP_3 2-aminoadipate transaminase 0.009033549783549784 prot_P47039 + 2-oxoadipic acid + L-glutamate --> 2-oxoglutarate + L-2-aminoadipate 0.032939964005654 r_0018_REV_EXP_1 2-aminoadipate transaminase (reversible) 0.7210471896303212 prot_P10356 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 r_0018_REV_EXP_2 2-aminoadipate transaminase (reversible) 0.8480978260869565 prot_P53090 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 r_0018_REV_EXP_3 2-aminoadipate transaminase (reversible) 1.8137766188613647 prot_P47039 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 -r_0019 2-dehydropantoate 2-reductase 0.4757888888888889 prot_P38787 + 2-dehydropantoate + H+ + NADPH --> (R)-pantoate + NADP(+) 1.900000061125771e-05 +r_0019 2-dehydropantoate 2-reductase 0.4757888888888889 prot_P38787 + 2-dehydropantoate + H+ + NADPH --> (R)-pantoate + NADP(+) 1.9000000611286447e-05 r_0020_EXP_1 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09351092896174863 prot_P14843 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 -r_0020_EXP_2 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.07609464734991835 +r_0020_EXP_2 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.033452483325451324 r_0021 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase 0.2834173315594083 prot_O13525 + 0.266570923780901 prot_P27680 + 0.191209663200305 prot_P41735 + 0.2544937516539746 prot_P49017 + 0.39274288726487816 prot_P53318 + 0.21981040253855474 prot_Q05779 + 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine --> 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + S-adenosyl-L-homocysteine 0.0 r_0022 2-hexaprenyl-6-methoxyphenol monooxygenase 0.5305538973582232 prot_O13525 + 0.49901762096258073 prot_P27680 + 0.3579422312153493 prot_P41735 + 0.47640929737929355 prot_P49017 + 0.7352100464414428 prot_P53318 + 0.4114824774654426 prot_Q05779 + 2-hexaprenyl-6-methoxyphenol + oxygen --> 2-hexaprenyl-6-methoxy-1,4-benzoquinone + H2O 0.0 r_0023 2-isopropylmalate hydratase 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> 2-isopropylmalate 0.0 -r_0023_REV 2-isopropylmalate hydratase (reversible) 0.8071027799745517 prot_P07264 + 2-isopropylmalate --> 2-isopropylmaleic acid + H2O 0.23822983307396556 +r_0023_REV 2-isopropylmalate hydratase (reversible) 0.8071027799745517 prot_P07264 + 2-isopropylmalate --> 2-isopropylmaleic acid + H2O 0.22142449525717553 r_0024_EXP_1 2-isopropylmalate synthase 1.3779912980420594 prot_P06208 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.0 -r_0024_EXP_2 2-isopropylmalate synthase 1.353637901861252 prot_Q12166 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.2382298330739352 +r_0024_EXP_2 2-isopropylmalate synthase 1.353637901861252 prot_Q12166 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.22142449525717553 r_0025 2-isopropylmalate synthase 1.3779912980420594 prot_P06208 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.0 r_0026_EXP_1 2-keto-4-methylthiobutyrate transamination 0.011265116279069768 prot_P38891 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 r_0026_EXP_2 2-keto-4-methylthiobutyrate transamination 0.010755813953488373 prot_P47176 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0012297510243303755 @@ -44,10 +44,10 @@ r_0026_EXP_3 2-keto-4-methylthiobutyrate transamination 1.219140625 prot_P53090 r_0026_EXP_4 2-keto-4-methylthiobutyrate transamination 1.5784250269687163 prot_P38840 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 r_0027 2-methylcitrate dehydratase 8.195345706873871 prot_P49367 + homocitrate --> but-1-ene-1,2,4-tricarboxylic acid + H2O 0.032939964005654 r_0027_REV 2-methylcitrate dehydratase (reversible) 8.350111111111111 prot_P49367 + but-1-ene-1,2,4-tricarboxylic acid + H2O --> homocitrate 0.0 -r_0028 2-methylcitrate synthase 0.10578556263269638 prot_P43635 + H2O + oxaloacetate + propionyl-CoA --> 2-methylcitrate + coenzyme A + H+ 7.487836586737207e-05 -r_0029 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.23822983307396556 +r_0028 2-methylcitrate synthase 0.10578556263269638 prot_P43635 + H2O + oxaloacetate + propionyl-CoA --> 2-methylcitrate + coenzyme A + H+ 7.48783658978421e-05 +r_0029 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.22142449525717553 r_0030 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.0 -r_0032 3',5'-bisphosphate nucleotidase 0.9886111111111111 prot_P32179 + adenosine 3',5'-bismonophosphate + H2O --> AMP + phosphate 0.024751737955090527 +r_0032 3',5'-bisphosphate nucleotidase 0.9886111111111111 prot_P32179 + adenosine 3',5'-bismonophosphate + H2O --> AMP + phosphate 0.024632488788954614 r_0033_EXP_1 3',5'-cyclic-nucleotide phosphodiesterase 0.5557671957671958 prot_P22434 + 3',5'-cyclic AMP + H2O --> AMP + H+ 0.0 r_0033_EXP_2 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic AMP + H2O --> AMP + H+ 0.0 r_0034 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic dAMP + H2O --> dAMP + H+ 0.0 @@ -55,36 +55,36 @@ r_0035 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + r_0036 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic GMP + H2O --> GMP + H+ 0.0 r_0037 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic CMP + H2O --> CMP + H+ 0.0 r_0038 3,4-dihydroxy-2-butanone-4-phosphate synthase 2.8494949494949493 prot_Q99258 + D-ribulose 5-phosphate --> 2-hydroxy-3-oxobutyl phosphate + formate + H+ 0.00019999999421997937 -r_0039 3-dehydroquinate dehydratase 0.1565905017921147 prot_P08566 + 3-dehydroquinate --> 3-dehydroshikimate + H2O 0.07609464734991835 -r_0040 3-dehydroquinate synthase 0.1565905017921147 prot_P08566 + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 3-dehydroquinate + phosphate 0.07609464734991835 +r_0039 3-dehydroquinate dehydratase 0.1565905017921147 prot_P08566 + 3-dehydroquinate --> 3-dehydroshikimate + H2O 0.033452483325451324 +r_0040 3-dehydroquinate synthase 0.1565905017921147 prot_P08566 + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 3-dehydroquinate + phosphate 0.033452483325451324 r_0041 3-dehydrosphinganine reductase 9.338785046728972 prot_P38342 + 3-ketosphinganine + H+ + NADPH --> NADP(+) + sphinganine 0.0 r_0042_EXP_1 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 r_0042_EXP_2 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09351092896174863 prot_P14843 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 r_0043_EXP_1 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase 0.2467406921478821 prot_Q12184 + 3-hexaprenyl-4-hydroxybenzoic acid + 0.5 oxygen --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 r_0043_EXP_2 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase 0.30872310057092667 prot_P48360 + 3-hexaprenyl-4-hydroxybenzoic acid + 0.5 oxygen --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 r_0044 3-hexaprenyl-4-hydroxy-5-methoxybenzoate decarboxylase 1.6143115942028985 prot_P33751 + 3.391545893719807 prot_Q03034 + 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid + H+ --> 2-hexaprenyl-6-methoxyphenol + carbon dioxide 0.0 -r_0045 3-hydroxy-L-kynurenine hydrolase 4.0501587301587305 prot_Q05979 + 3-hydroxy-L-kynurenine + H2O --> 3-hydroxyanthranilate + H+ + L-alanine 0.0006071199974008957 -r_0057 3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxytetradecanoyl-CoA + NAD --> 3-oxotetradecanoyl-CoA + H+ + NADH 0.000536549525352524 -r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.22483333333333333 prot_P47096 + 3-hydroxyanthranilate + oxygen --> 2-amino-3-carboxymuconate-6-semialdehyde 0.0006071199974008957 +r_0045 3-hydroxy-L-kynurenine hydrolase 4.0501587301587305 prot_Q05979 + 3-hydroxy-L-kynurenine + H2O --> 3-hydroxyanthranilate + H+ + L-alanine 0.0006069999973934842 +r_0057 3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxytetradecanoyl-CoA + NAD --> 3-oxotetradecanoyl-CoA + H+ + NADH 0.0 +r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.22483333333333333 prot_P47096 + 3-hydroxyanthranilate + oxygen --> 2-amino-3-carboxymuconate-6-semialdehyde 0.0006069999973934842 r_0059 3-isopropylmalate 3-methyltransferase 195.1806339044363 prot_P32643 + (2R,3S)-3-isopropylmalate + S-adenosyl-L-methionine --> 3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoate + S-adenosyl-L-homocysteine 0.0 r_0060 3-isopropylmalate dehydratase 0.6097968324816225 prot_P07264 + (2R,3S)-3-isopropylmalate --> 2-isopropylmaleic acid + H2O 0.0 -r_0060_REV 3-isopropylmalate dehydratase (reversible) 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> (2R,3S)-3-isopropylmalate 0.23822983307396556 -r_0061 3-isopropylmalate dehydrogenase 0.06638207225630538 prot_P04173 + (2R,3S)-3-isopropylmalate + NAD --> (2S)-2-isopropyl-3-oxosuccinate + H+ + NADH 0.23822983307396556 +r_0060_REV 3-isopropylmalate dehydratase (reversible) 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> (2R,3S)-3-isopropylmalate 0.22142449525717553 +r_0061 3-isopropylmalate dehydrogenase 0.06638207225630538 prot_P04173 + (2R,3S)-3-isopropylmalate + NAD --> (2S)-2-isopropyl-3-oxosuccinate + H+ + NADH 0.22142449525717553 r_0062_EXP_1 3-methyl-2-oxobutanoate decarboxylase 0.27589605734767025 prot_P26263 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 r_0062_EXP_2 3-methyl-2-oxobutanoate decarboxylase 0.11780651340996169 prot_P06169 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 r_0062_EXP_3 3-methyl-2-oxobutanoate decarboxylase 0.27738351254480287 prot_P16467 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 -r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.226834113807293 prot_P38122 + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O --> 2-dehydropantoate + THF 1.900000061125771e-05 +r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.226834113807293 prot_P38122 + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O --> 2-dehydropantoate + THF 1.9000000611286447e-05 r_0064_EXP_1 3-methyl-2-oxopentanoate decarboxylase 0.13096934865900384 prot_Q07471 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_2 3-methyl-2-oxopentanoate decarboxylase 0.27589605734767025 prot_P26263 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_3 3-methyl-2-oxopentanoate decarboxylase 0.11780651340996169 prot_P06169 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_4 3-methyl-2-oxopentanoate decarboxylase 0.27738351254480287 prot_P16467 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 -r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 1.4447337962962963 prot_P08566 + 3-phosphoshikimic acid + phosphoenolpyruvate --> 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid + phosphate 0.07609464734991835 -r_0066 4-amino-4-deoxychorismate synthase 1446.797385620915 prot_P37254 + chorismate + L-glutamine --> 4-amino-4-deoxychorismate + L-glutamate 6.340000254510467e-06 -r_0067 4-aminobenzoate synthase 6.233918128654971 prot_Q03266 + 4-amino-4-deoxychorismate --> 4-aminobenzoate + H+ + pyruvate 6.340000254510467e-06 -r_0068 4-aminobutyrate transaminase 43.25653594771242 prot_P17649 + 2-oxoglutarate + gamma-aminobutyrate --> L-glutamate + succinic semialdehyde 0.0 +r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 1.4447337962962963 prot_P08566 + 3-phosphoshikimic acid + phosphoenolpyruvate --> 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid + phosphate 0.033452483325451324 +r_0066 4-amino-4-deoxychorismate synthase 1446.797385620915 prot_P37254 + chorismate + L-glutamine --> 4-amino-4-deoxychorismate + L-glutamate 6.340000254623224e-06 +r_0067 4-aminobenzoate synthase 6.233918128654971 prot_Q03266 + 4-amino-4-deoxychorismate --> 4-aminobenzoate + H+ + pyruvate 6.340000254623224e-06 +r_0068 4-aminobutyrate transaminase 43.25653594771242 prot_P17649 + 2-oxoglutarate + gamma-aminobutyrate --> L-glutamate + succinic semialdehyde 0.00022698358235192912 r_0069 4-hydroxy-L-threonine synthase 0.003912990196078431 prot_P16120 + 4-(phosphonooxy)-L-threonine + H2O --> 4-hydroxy-L-threonine + phosphate 0.0 r_0070 4-hydroxybenzoate formation 0.6162073031087573 prot_standard + 4-hydroxybenzoyl-CoA + H2O --> 4-hydroxybenzoate + coenzyme A + H+ 0.0 -r_0072 4-methyl-2-oxopentanoate decarboxylase 2.2341830065359476 prot_Q07471 + 4-methyl-2-oxopentanoate + H+ --> 3-methylbutanal + carbon dioxide 0.20197750367945705 +r_0072 4-methyl-2-oxopentanoate decarboxylase 2.2341830065359476 prot_Q07471 + 4-methyl-2-oxopentanoate + H+ --> 3-methylbutanal + carbon dioxide 0.18517216586266702 r_0073_EXP_1 4PP-IP5 depyrophosphorylation to IP6 0.9485014619883041 prot_Q06685 + 4-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0073_EXP_2 4PP-IP5 depyrophosphorylation to IP6 2396.8888888888887 prot_Q99321 + 4-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0074 4PP-IP5 pyrophosphorylation to 4,5-PP2-IP4 1106.9444444444443 prot_Q12494 + 4-diphospho-1D-myo-inositol pentakisphosphate + ATP + H+ --> 4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate + ADP 0.0 @@ -94,8 +94,8 @@ r_0076_EXP_2 5'-nucleotidase (CMP) 51.769157967243395 prot_P53078 + CMP + H2O -- r_0077 5'-nucleotidase (IMP) 1.056172839506173 prot_Q99312 + H2O + IMP --> inosine + phosphate 0.0 r_0078_EXP_1 5'-nucleotidase (UMP) 0.029597457627118642 prot_P40025 + H2O + UMP --> phosphate + uridine 0.0 r_0078_EXP_2 5'-nucleotidase (UMP) 201.12835425109543 prot_P53078 + H2O + UMP --> phosphate + uridine 0.0 -r_0079 5'-phosphoribosylformyl glycinamidine synthetase 112.56379587281619 prot_P38972 + 5'-phosphoribosyl-N-formylglycineamide + ATP + H2O + L-glutamine --> 5'-phosphoribosyl-N-formylglycineamidine + ADP + H+ + L-glutamate + phosphate 0.010240426385252575 -r_0080_EXP_1 5,10-methylenetetrahydrofolate reductase (NADPH) 0.12837152777777777 prot_P46151 + 0.11902777777777777 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.02225559248037856 +r_0079 5'-phosphoribosylformyl glycinamidine synthetase 112.56379587281619 prot_P38972 + 5'-phosphoribosyl-N-formylglycineamide + ATP + H2O + L-glutamine --> 5'-phosphoribosyl-N-formylglycineamidine + ADP + H+ + L-glutamate + phosphate 0.010240426385254225 +r_0080_EXP_1 5,10-methylenetetrahydrofolate reductase (NADPH) 0.12837152777777777 prot_P46151 + 0.11902777777777777 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.02225559248014866 r_0080_EXP_2 5,10-methylenetetrahydrofolate reductase (NADPH) 0.3705144833549503 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.0 r_0081 5-aminolevulinate synthase 0.08588252314814815 prot_P09950 + H+ + L-glycine + succinyl-CoA --> 5-aminolevulinate + carbon dioxide + coenzyme A 0.0 r_0082 5-diphosphoinositol-1,2,3,4,6-pentakisphosphate diphosphohydrolase 2396.8888888888887 prot_Q99321 + 5-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 @@ -112,7 +112,7 @@ r_0089_REV 5PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 (reversible) 0.94850146198 r_0090_EXP_1 6-phosphofructo-2-kinase 0.4896069182389937 prot_P40433 + ATP + D-fructose 6-phosphate --> ADP + beta-D-fructose 2,6-bisphosphate + H+ 0.0 r_0090_EXP_2 6-phosphofructo-2-kinase 0.23751572327044027 prot_Q12471 + ATP + D-fructose 6-phosphate --> ADP + beta-D-fructose 2,6-bisphosphate + H+ 0.0 r_0091_EXP_1 6-phosphogluconolactonase 0.8951362104267674 prot_P53315 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.0 -r_0091_EXP_2 6-phosphogluconolactonase 0.87424298616765 prot_P38858 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 2.2864587827242655e-13 +r_0091_EXP_2 6-phosphogluconolactonase 0.87424298616765 prot_P38858 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.0 r_0092_EXP_1 6PP-IP5 depyrophosphorylation to IP6 0.9485014619883041 prot_Q06685 + 6-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0092_EXP_2 6PP-IP5 depyrophosphorylation to IP6 2396.8888888888887 prot_Q99321 + 6-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0093 6PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 1106.9444444444443 prot_Q12494 + 6-diphospho-1D-myo-inositol pentakisphosphate + ATP + H+ --> 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + ADP 0.0 @@ -120,26 +120,26 @@ r_0094 8-amino-7-oxononanoate synthase 1.1329040404040405 prot_standard + H+ + L r_0095_EXP_1 acetaldehyde condensation 0.27589605734767025 prot_P26263 + 2.0 acetaldehyde --> (R)-acetoin 0.0 r_0095_EXP_2 acetaldehyde condensation 0.11780651340996169 prot_P06169 + 2.0 acetaldehyde --> (R)-acetoin 0.0 r_0095_EXP_3 acetaldehyde condensation 0.27738351254480287 prot_P16467 + 2.0 acetaldehyde --> (R)-acetoin 0.0 -r_0096 acetohydroxy acid isomeroreductase 0.6734669095324833 prot_P06168 + 2-acetyllactic acid + H+ + NADPH --> (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) 0.2697092880520629 +r_0096 acetohydroxy acid isomeroreductase 0.6734669095324833 prot_P06168 + 2-acetyllactic acid + H+ + NADPH --> (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) 0.2529039502352728 r_0097_EXP_1 acetolactate synthase 0.16199092088197148 prot_P07342 + 0.07346952010376134 prot_P25605 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.0 -r_0097_EXP_2 acetolactate synthase 0.08099546044098574 prot_P07342 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.2697092880520629 +r_0097_EXP_2 acetolactate synthase 0.08099546044098574 prot_P07342 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.2529039502352728 r_0099 acetyl-CoA ACP transacylase 0.2585296857817232 prot_P32463 + acetyl-CoA + ACP1 --> acetyl-ACP + coenzyme A 0.0 r_0099_REV acetyl-CoA ACP transacylase (reversible) 0.29722261474049355 prot_P32463 + acetyl-ACP + coenzyme A --> acetyl-CoA + ACP1 0.0 -r_0100 acetyl-CoA C-acyltransferase (palmitoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxooctadecanoyl-CoA + coenzyme A --> acetyl-CoA + palmitoyl-CoA 0.0007372482901629971 -r_0101 acetyl-CoA C-acyltransferase (tetracosanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxohexacosanoyl-CoA + coenzyme A --> acetyl-CoA + tetracosanoyl-CoA 0.00032289641279162194 -r_0102 acetyl-CoA C-acyltransferase (myristoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxopalmitoyl-CoA + coenzyme A --> acetyl-CoA + myristoyl-CoA 0.0007372482900567666 +r_0100 acetyl-CoA C-acyltransferase (palmitoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxooctadecanoyl-CoA + coenzyme A --> acetyl-CoA + palmitoyl-CoA 0.0 +r_0101 acetyl-CoA C-acyltransferase (tetracosanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxohexacosanoyl-CoA + coenzyme A --> acetyl-CoA + tetracosanoyl-CoA 0.0 +r_0102 acetyl-CoA C-acyltransferase (myristoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxopalmitoyl-CoA + coenzyme A --> acetyl-CoA + myristoyl-CoA 0.0 r_0103 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.0 r_0103_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA 0.0 -r_0104 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.02234772406386473 +r_0104 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.022126459469172983 r_0104_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA 0.0 -r_0105 acetyl-CoA C-acyltransferase (lauroyl-CoA) 0.839527027027027 prot_P27796 + 3-oxotetradecanoyl-CoA + coenzyme A --> acetyl-CoA + lauroyl-CoA 0.000536549525352524 -r_0106 acetyl-CoA C-acyltransferase (octanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxodecanoyl-CoA + coenzyme A --> acetyl-CoA + octanoyl-CoA 0.0005698445731318472 -r_0107 acetyl-CoA C-acyltransferase (decanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxolauroyl-CoA + coenzyme A --> acetyl-CoA + decanoyl-CoA 0.0 +r_0105 acetyl-CoA C-acyltransferase (lauroyl-CoA) 0.839527027027027 prot_P27796 + 3-oxotetradecanoyl-CoA + coenzyme A --> acetyl-CoA + lauroyl-CoA 0.0 +r_0106 acetyl-CoA C-acyltransferase (octanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxodecanoyl-CoA + coenzyme A --> acetyl-CoA + octanoyl-CoA 0.00016913831181727956 +r_0107 acetyl-CoA C-acyltransferase (decanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxolauroyl-CoA + coenzyme A --> acetyl-CoA + decanoyl-CoA 0.00016913831181727956 r_0108 acetyl-Coa carboxylase 8.46937908496732 prot_P32874 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.0 -r_0109 acetyl-CoA carboxylase, reaction 2.608229839040149 prot_P48445 + 8.55097579839999 prot_Q00955 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.12568836205411316 +r_0109 acetyl-CoA carboxylase, reaction 2.608229839040149 prot_P48445 + 8.55097579839999 prot_Q00955 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.11958078646830983 r_0111 acetyl-CoA hydrolase 2.24640342822161 prot_P32316 + acetyl-CoA + H2O --> acetate + coenzyme A + H+ 0.0 r_0112_EXP_1 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 -r_0112_EXP_2 acetyl-CoA synthetase 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.4875254727466943 +r_0112_EXP_2 acetyl-CoA synthetase 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.5800198031120798 r_0113 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.04174434957176782 r_0114 acetyl-CoA synthetase nuclear 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 r_0115 acetylglutamate kinase 3.4224025974025976 prot_Q01217 + ATP + N-acetyl-L-glutamate --> ADP + N-acetyl-L-gamma-glutamyl phosphate 0.031792910688328326 @@ -147,16 +147,16 @@ r_0116_EXP_1 acid phosphatase (secreted) 12.535888834043245 prot_P00635 + FMN + r_0116_EXP_2 acid phosphatase (secreted) 2.079636552290633 prot_P35842 + FMN + H2O --> phosphate + riboflavin 0.0 r_0116_EXP_3 acid phosphatase (secreted) 8.09317955304032 prot_P24031 + FMN + H2O --> phosphate + riboflavin 0.0 r_0116_EXP_4 acid phosphatase (secreted) 2.0162205390505443 prot_P38693 + FMN + H2O --> phosphate + riboflavin 0.0 -r_0117 aconitase 356.0740740740741 prot_Q12428 + 2-methylcitrate --> (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid 7.487836586737207e-05 +r_0117 aconitase 356.0740740740741 prot_Q12428 + 2-methylcitrate --> (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid 7.487836589784212e-05 r_0117_REV aconitase (reversible) 0.0015170737865303288 prot_Q12428 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> 2-methylcitrate 0.0 r_0118 acteylornithine transaminase 5.836456209941037 prot_P18544 + 2-acetamido-5-oxopentanoate + L-glutamate --> 2-oxoglutarate + N(2)-acetyl-L-ornithine 0.031792910688328326 -r_0119 acyl carrier protein synthase 1.9814484126984127 prot_Q12036 + coenzyme A + H2O --> adenosine 3',5'-bismonophosphate + 2.0 H+ + pantetheine 4'-phosphate 0.01270757217538068 -r_0120 acyl-CoA oxidase (decanoyl-CoA) 15.258169934640524 prot_P13711 + decanoyl-CoA + oxygen --> hydrogen peroxide + trans-dec-2-enoyl-CoA 0.0 +r_0119 acyl carrier protein synthase 1.9814484126984127 prot_Q12036 + coenzyme A + H2O --> adenosine 3',5'-bismonophosphate + 2.0 H+ + pantetheine 4'-phosphate 0.012707572175380651 +r_0120 acyl-CoA oxidase (decanoyl-CoA) 15.258169934640524 prot_P13711 + decanoyl-CoA + oxygen --> hydrogen peroxide + trans-dec-2-enoyl-CoA 0.00016913831181727956 r_0121 acyl-CoA oxidase (dodecanoyl-CoA) 2.7176949941792783 prot_P13711 + lauroyl-CoA + oxygen --> hydrogen peroxide + trans-dodec-2-enoyl-CoA 0.0 -r_0122 acyl-CoA oxidase (hexacosanoyl-CoA) 2.7176949941792783 prot_P13711 + hexacosanoyl-CoA + oxygen --> hydrogen peroxide + trans-hexacos-2-enoyl-CoA 0.00032289641279162194 -r_0123 acyl-CoA oxidase (hexadecanoyl-CoA) 0.2992948717948718 prot_P13711 + oxygen + palmitoyl-CoA --> hexadec-2-enoyl-CoA + hydrogen peroxide 0.0007372482900567666 -r_0124 acyl-CoA oxidase (octadecanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + stearoyl-CoA --> hydrogen peroxide + trans-octadec-2-enoyl-CoA 0.0007372482901629971 -r_0125 acyl-CoA oxidase (tetradecanoyl-CoA) 2.7176949941792783 prot_P13711 + myristoyl-CoA + oxygen --> hydrogen peroxide + trans-tetradec-2-enoyl-CoA 0.000536549525352524 +r_0122 acyl-CoA oxidase (hexacosanoyl-CoA) 2.7176949941792783 prot_P13711 + hexacosanoyl-CoA + oxygen --> hydrogen peroxide + trans-hexacos-2-enoyl-CoA 0.0 +r_0123 acyl-CoA oxidase (hexadecanoyl-CoA) 0.2992948717948718 prot_P13711 + oxygen + palmitoyl-CoA --> hexadec-2-enoyl-CoA + hydrogen peroxide 0.0 +r_0124 acyl-CoA oxidase (octadecanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + stearoyl-CoA --> hydrogen peroxide + trans-octadec-2-enoyl-CoA 0.0 +r_0125 acyl-CoA oxidase (tetradecanoyl-CoA) 2.7176949941792783 prot_P13711 + myristoyl-CoA + oxygen --> hydrogen peroxide + trans-tetradec-2-enoyl-CoA 0.0 r_0126 acyl-CoA:sterol acyltransferase (oleoyl-CoA:episterol), ER membrane 65.94767724903261 prot_P25628 + oleoyl-CoA + episterol --> coenzyme A + episteryl oleate 0.0 r_0126_REV acyl-CoA:sterol acyltransferase (oleoyl-CoA:episterol), ER membrane (reversible) 3.9740642147807406 prot_P25628 + coenzyme A + episteryl oleate --> oleoyl-CoA + episterol 0.0 r_0127_EXP_1 acyl-CoA:sterol acyltransferase (oleoyl-CoA:ergosterol), ER membrane 64.38822905167784 prot_P25628 + oleoyl-CoA + ergosterol --> coenzyme A + ergosteryl oleate 0.0 @@ -176,7 +176,7 @@ r_0133 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:fecosterol), ER membran r_0133_REV acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:fecosterol), ER membrane (reversible) 3.9740642147807406 prot_P25628 + coenzyme A + fecosteryl palmitoleate --> palmitoleoyl-CoA(4-) + fecosterol 0.0 r_0134 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:lanosterol), ER membrane 57.54568671113769 prot_P25628 + palmitoleoyl-CoA(4-) + lanosterol --> coenzyme A + lanosteryl palmitoleate 0.0 r_0134_REV acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:lanosterol), ER membrane (reversible) 2.799291523044568 prot_P25628 + coenzyme A + lanosteryl palmitoleate --> palmitoleoyl-CoA(4-) + lanosterol 0.0 -r_0135 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:zymosterol), ER membrane 57.54568671113769 prot_P25628 + palmitoleoyl-CoA(4-) + zymosterol --> coenzyme A + zymosteryl palmitoleate 3.687743221822545e-05 +r_0135 acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:zymosterol), ER membrane 57.54568671113769 prot_P25628 + palmitoleoyl-CoA(4-) + zymosterol --> coenzyme A + zymosteryl palmitoleate 0.0 r_0135_REV acyl-CoA:sterol acyltransferase (palmitoleoyl-CoA:zymosterol), ER membrane (reversible) 2.799291523044568 prot_P25628 + coenzyme A + zymosteryl palmitoleate --> palmitoleoyl-CoA(4-) + zymosterol 0.0 r_0137 acylation of GPI inositol at 2 position, GPI-anchor assembly, step 3 3.2386098042061775 prot_P47026 + 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + palmitoyl-CoA --> 6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol + coenzyme A 0.0 r_0137_REV acylation of GPI inositol at 2 position, GPI-anchor assembly, step 3 (reversible) 5.267157776137904 prot_P47026 + 6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol + coenzyme A --> 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + palmitoyl-CoA 0.0 @@ -184,23 +184,23 @@ r_0138 adenine deaminase 2.0017676767676766 prot_P53909 + adenine + H+ + H2O --> r_0139_EXP_1 adenine phosphoribosyltransferase 0.5950339406931047 prot_P36973 + adenine + PRPP --> AMP + diphosphate 0.0 r_0139_EXP_2 adenine phosphoribosyltransferase 0.6129272359175896 prot_P49435 + adenine + PRPP --> AMP + diphosphate 0.0 r_0140 adenosine deaminase 2.0017676767676766 prot_P53909 + adenosine + H+ + H2O --> ammonium + inosine 0.0 -r_0142 adenosine kinase 0.3962091503267974 prot_P47143 + adenosine + ATP --> ADP + AMP + H+ 0.015335596857434765 +r_0142 adenosine kinase 0.3962091503267974 prot_P47143 + adenosine + ATP --> ADP + AMP + H+ 0.01533559685720487 r_0143 adenosine monophosphate deaminase 21.282895302745313 prot_P15274 + AMP + H+ + H2O --> ammonium + IMP 0.0 -r_0144 adenosylhomocysteinase 0.023732367149758453 prot_P39954 + H2O + S-adenosyl-L-homocysteine --> adenosine + L-homocysteine 0.01410584583310439 +r_0144 adenosylhomocysteinase 0.023732367149758453 prot_P39954 + H2O + S-adenosyl-L-homocysteine --> adenosine + L-homocysteine 0.014105845832874494 r_0145 adenosylmethionine decarboxylase 7.554248366013072 prot_P21182 + H+ + S-adenosyl-L-methionine --> carbon dioxide + S-adenosylmethioninamine 0.0012297510243303755 r_0146 adenosylmethionine-8-amino-7-oxononanoate transaminase 14.919166666666667 prot_P50277 + 8-amino-7-oxononanoate + S-adenosyl-L-methionine --> 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate 0.0 r_0146_REV adenosylmethionine-8-amino-7-oxononanoate transaminase (reversible) 14.919166666666667 prot_P50277 + 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate --> 8-amino-7-oxononanoate + S-adenosyl-L-methionine 0.0 r_0147 adenylate cyclase 0.013758091787439614 prot_P08678 + ATP --> 3',5'-cyclic AMP + diphosphate 0.0 r_0148_EXP_1 adenylate kinase 0.007176741835638936 prot_Q12055 + AMP + ATP --> 2.0 ADP 0.21637275374138842 -r_0148_EXP_2 adenylate kinase 0.007660602615122228 prot_P07170 + AMP + ATP --> 2.0 ADP 0.8518042358274189 +r_0148_EXP_2 adenylate kinase 0.007660602615122228 prot_P07170 + AMP + ATP --> 2.0 ADP 0.9428487085665125 r_0149 adenylate kinase 10.450950897581233 prot_P26364 + AMP + ATP --> 2.0 ADP 0.0 -r_0150 adenylate kinase (GTP) 10.495327582667667 prot_P26364 + AMP + GTP --> ADP + GDP 0.04175068957202233 +r_0150 adenylate kinase (GTP) 10.495327582667667 prot_P26364 + AMP + GTP --> ADP + GDP 0.041750689572022444 r_0150_REV adenylate kinase (GTP) (reversible) 2.5045140533551153 prot_P26364 + ADP + GDP --> AMP + GTP 0.0 -r_0151 adenylosuccinate lyase (AICAR) 0.04493076162215628 prot_Q05911 + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole --> AICAR + fumarate 0.010240306385248333 -r_0152 adenylosuccinate lyase 0.04493076162215628 prot_Q05911 + adenylo-succinate --> AMP + fumarate 0.013797191947406182 +r_0151 adenylosuccinate lyase (AICAR) 0.04493076162215628 prot_Q05911 + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole --> AICAR + fumarate 0.01024030638524998 +r_0152 adenylosuccinate lyase 0.04493076162215628 prot_Q05911 + adenylo-succinate --> AMP + fumarate 0.013797191947407746 r_0152_REV adenylosuccinate lyase (reversible) 5.221264367816092 prot_Q05911 + AMP + fumarate --> adenylo-succinate 0.0 -r_0153 adenylosuccinate synthase 2.4383333333333335 prot_P80210 + GTP + IMP + L-aspartate --> adenylo-succinate + GDP + 2.0 H+ + phosphate 0.013797191947406182 -r_0154 adenylyl-sulfate kinase 1.4558080808080807 prot_Q02196 + 5'-adenylyl sulfate + ATP --> 3'-phospho-5'-adenylyl sulfate + ADP + H+ 0.012044165779709846 +r_0153 adenylosuccinate synthase 2.4383333333333335 prot_P80210 + GTP + IMP + L-aspartate --> adenylo-succinate + GDP + 2.0 H+ + phosphate 0.013797191947407746 +r_0154 adenylyl-sulfate kinase 1.4558080808080807 prot_Q02196 + 5'-adenylyl sulfate + ATP --> 3'-phospho-5'-adenylyl sulfate + ADP + H+ 0.011924916613573963 r_0155 ADP-ribose 2,3-cyclic phosphodiesterase 0.00789952718676123 prot_P53314 + 2',3'-cyclic AMP + H2O --> adenosine 2'-phosphate + H+ 0.0 r_0156 alanine glyoxylate aminotransferase 0.08886132315521629 prot_P43567 + glyoxylate + L-alanine --> L-glycine + pyruvate 0.0 r_0157 alanyl-tRNA synthetase 0.25476620370370373 prot_P40825 + ATP + L-alanine + tRNA(Ala) --> Ala-tRNA(Ala) + AMP + diphosphate 0.0347736630768556 @@ -209,7 +209,7 @@ r_0158_EXP_2 alcohol acetyltransferase (2-methylbutanol) 0.004358469008854613 pr r_0159_EXP_1 alcohol acetyltransferase (ethanol) 0.00442002285061411 prot_P53296 + acetyl-CoA + ethanol --> coenzyme A + ethyl acetate 0.0 r_0159_EXP_2 alcohol acetyltransferase (ethanol) 0.004358469008854613 prot_P40353 + acetyl-CoA + ethanol --> coenzyme A + ethyl acetate 0.0 r_0160_EXP_1 alcohol acetyltransferase (isoamyl alcohol) 0.00442002285061411 prot_P53296 + acetyl-CoA + isoamylol --> coenzyme A + isoamyl acetate 0.0 -r_0160_EXP_2 alcohol acetyltransferase (isoamyl alcohol) 0.004358469008854613 prot_P40353 + acetyl-CoA + isoamylol --> coenzyme A + isoamyl acetate 0.06938276692509104 +r_0160_EXP_2 alcohol acetyltransferase (isoamyl alcohol) 0.004358469008854613 prot_P40353 + acetyl-CoA + isoamylol --> coenzyme A + isoamyl acetate 0.18517216586266702 r_0161_EXP_1 alcohol acetyltransferase (isobutyl alcohol) 0.00442002285061411 prot_P53296 + acetyl-CoA + isobutanol --> coenzyme A + isobutyl acetate 0.0 r_0161_EXP_2 alcohol acetyltransferase (isobutyl alcohol) 0.004358469008854613 prot_P40353 + acetyl-CoA + isobutanol --> coenzyme A + isobutyl acetate 0.0 r_0162_EXP_1 alcohol acetyltransferase (phenylethanol alcohol) 0.00442002285061411 prot_P53296 + 2-phenylethanol + acetyl-CoA --> coenzyme A + phenethyl acetate 0.0 @@ -217,7 +217,7 @@ r_0162_EXP_2 alcohol acetyltransferase (phenylethanol alcohol) 0.004358469008854 r_0163 alcohol dehydrogenase (ethanol to acetaldehyde) 0.07135198135198136 prot_P00331 + ethanol + NAD --> acetaldehyde + H+ + NADH 0.0 r_0164_EXP_1 alcohol dehydrogenase (glycerol, NADP) 1.4852564102564103 prot_Q12458 + D-glyceraldehyde + H+ + NADPH --> glycerol + NADP(+) 0.0 r_0164_EXP_2 alcohol dehydrogenase (glycerol, NADP) 60.65196078431372 prot_P38715 + D-glyceraldehyde + H+ + NADPH --> glycerol + NADP(+) 0.0 -r_0165_EXP_1 mitochondrial alcohol dehydrogenase 0.012698148148148148 prot_P10127 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.09322272635413054 +r_0165_EXP_1 mitochondrial alcohol dehydrogenase 0.012698148148148148 prot_P10127 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.3487450805027756 r_0165_EXP_2 mitochondrial alcohol dehydrogenase 0.03581110330487606 prot_P07246 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.0 r_0166_EXP_1 aldehyde dehydrogenase (2-methylbutanol, NAD) 0.006354607630660375 prot_P38113 + 2-methylbutanal + H+ + NADH --> 2-methylbutanol + NAD 0.0 r_0166_EXP_2 aldehyde dehydrogenase (2-methylbutanol, NAD) 0.0069274810448778975 prot_P32771 + 2-methylbutanal + H+ + NADH --> 2-methylbutanol + NAD 0.0 @@ -236,10 +236,10 @@ r_0171_EXP_1 aldehyde dehydrogenase (2-phenylethanol, NADP) 1.6815384615384616 p r_0171_EXP_2 aldehyde dehydrogenase (2-phenylethanol, NADP) 0.012227777777777778 prot_Q04894 + H+ + NADPH + phenylacetaldehyde --> 2-phenylethanol + NADP(+) 0.0 r_0172_EXP_1 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.483596214511041 prot_P47771 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 0.0 r_0172_EXP_2 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.06410300925925926 prot_P54114 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 0.0012297510243303755 -r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.3170557221103246 -r_0174 aldehyde dehydrogenase (acetylaldehyde, NAD) 1.6231765567058962 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 1.8332231371810725 -r_0175_EXP_1 aldehyde dehydrogenase (acetylaldehyde, NADP) 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.004105805773497554 -r_0175_EXP_2 aldehyde dehydrogenase (acetylaldehyde, NADP) 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.3239454249843128 +r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 1.04513435341851 +r_0174 aldehyde dehydrogenase (acetylaldehyde, NAD) 1.6231765567058962 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 +r_0175_EXP_1 aldehyde dehydrogenase (acetylaldehyde, NADP) 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.0 +r_0175_EXP_2 aldehyde dehydrogenase (acetylaldehyde, NADP) 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.11325326002381908 r_0176 aldehyde dehydrogenase (indole-3-acetaldehyde, NAD) 2.9233283159832175 prot_P46367 + H2O + indol-3-ylacetaldehyde + NAD --> 2.0 H+ + indole-3-acetate + NADH 0.0 r_0177 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + H2O + indol-3-ylacetaldehyde + NADP(+) --> 2.0 H+ + indole-3-acetate + NADPH 0.0 r_0178_EXP_1 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 2.027300005914026 prot_P40047 + H2O + indol-3-ylacetaldehyde + NADP(+) --> 2.0 H+ + indole-3-acetate + NADPH 0.0 @@ -248,7 +248,7 @@ r_0179_EXP_1 aldehyde dehydrogenase (isoamyl alcohol, NAD) 0.006354607630660375 r_0179_EXP_2 aldehyde dehydrogenase (isoamyl alcohol, NAD) 0.0069274810448778975 prot_P32771 + 3-methylbutanal + H+ + NADH --> isoamylol + NAD 0.0 r_0179_EXP_3 aldehyde dehydrogenase (isoamyl alcohol, NAD) 0.011373148148148148 prot_P00330 + 3-methylbutanal + H+ + NADH --> isoamylol + NAD 0.0 r_0180_EXP_1 aldehyde dehydrogenase (isoamyl alcohol, NAD) 0.012698148148148148 prot_P10127 + 3-methylbutanal + H+ + NADH --> isoamylol + NAD 0.0 -r_0180_EXP_2 aldehyde dehydrogenase (isoamyl alcohol, NAD) 0.006814054134343373 prot_P07246 + 3-methylbutanal + H+ + NADH --> isoamylol + NAD 0.06938276692509104 +r_0180_EXP_2 aldehyde dehydrogenase (isoamyl alcohol, NAD) 0.006814054134343373 prot_P07246 + 3-methylbutanal + H+ + NADH --> isoamylol + NAD 0.18517216586266702 r_0181_EXP_1 aldehyde dehydrogenase (isoamyl alcohol, NADP) 0.0011407994990084542 prot_P25377 + 3-methylbutanal + H+ + NADPH --> isoamylol + NADP(+) 0.0 r_0181_EXP_2 aldehyde dehydrogenase (isoamyl alcohol, NADP) 0.012227777777777778 prot_Q04894 + 3-methylbutanal + H+ + NADPH --> isoamylol + NADP(+) 0.0 r_0182_EXP_1 aldehyde dehydrogenase (isobutyl alcohol, NAD) 0.006354607630660375 prot_P38113 + H+ + isobutyraldehyde + NADH --> isobutanol + NAD 0.0 @@ -265,7 +265,7 @@ r_0186_EXP_2 aldehyde dehydrogenase (tryptophol, NAD) 0.0069274810448778975 prot r_0186_EXP_3 aldehyde dehydrogenase (tryptophol, NAD) 0.011373148148148148 prot_P00330 + H+ + indol-3-ylacetaldehyde + NADH --> NAD + tryptophol 0.0 r_0187_EXP_1 aldehyde dehydrogenase (tryptophol, NAD) 0.012698148148148148 prot_P10127 + H+ + indol-3-ylacetaldehyde + NADH --> NAD + tryptophol 0.0 r_0187_EXP_2 aldehyde dehydrogenase (tryptophol, NAD) 0.006814054134343373 prot_P07246 + H+ + indol-3-ylacetaldehyde + NADH --> NAD + tryptophol 0.0 -r_0188 alkaline phosphatase (dihydroneopterin) 0.6294430181013366 prot_P11491 + 7,8-dihydroneopterin 3'-triphosphate + 3.0 H2O --> 7,8-dihydroneopterin + 2.0 H+ + 3.0 phosphate 6.340000254510467e-06 +r_0188 alkaline phosphatase (dihydroneopterin) 0.6294430181013366 prot_P11491 + 7,8-dihydroneopterin 3'-triphosphate + 3.0 H2O --> 7,8-dihydroneopterin + 2.0 H+ + 3.0 phosphate 6.340000254623224e-06 r_0189 allantoate amidinohydrolase 0.014338518518518518 prot_P25335 + allantoate + H2O --> urea + ureidoglycolic acid 0.0 r_0189_REV allantoate amidinohydrolase (reversible) 0.014338518518518518 prot_P25335 + urea + ureidoglycolic acid --> allantoate + H2O 0.0 r_0190 allantoinase, reaction 0.033152116402116405 prot_P32375 + allantoin + H2O --> allantoate + H+ 0.0 @@ -294,8 +294,8 @@ r_0199_EXP_1 amidase 0.002363959719142646 prot_P22580 + 4-guanidinobutanamide + r_0199_EXP_2 amidase 0.002263428815277111 prot_Q03557 + 4-guanidinobutanamide + H2O --> 4-guanidinobutanoic acid + ammonium 0.0 r_0200 Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing) 0.062476381011109826 prot_standard + aminoacetone + H2O + oxygen --> ammonium + hydrogen peroxide + methylglyoxal 0.0 r_0201 Aminobutyraldehyde dehydrogenase 6.571504396261395 prot_P46367 + 4-aminobutanal + H2O + NAD --> gamma-aminobutyrate + 2.0 H+ + NADH 0.0 -r_0202 anthranilate phosphoribosyltransferase 2.8570423609142406 prot_P07285 + anthranilate + PRPP --> diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate 0.004508621257677621 -r_0203 anthranilate synthase 0.11426731078904992 prot_P00899 + 0.1076670692431562 prot_P00937 + chorismate + L-glutamine --> anthranilate + H+ + L-glutamate + pyruvate 0.004464101443246716 +r_0202 anthranilate phosphoribosyltransferase 2.8570423609142406 prot_P07285 + anthranilate + PRPP --> diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate 0.004508621257685833 +r_0203 anthranilate synthase 0.11426731078904992 prot_P00899 + 0.1076670692431562 prot_P00937 + chorismate + L-glutamine --> anthranilate + H+ + L-glutamate + pyruvate 0.004463981443239305 r_0204 Ap4A hydrolase 0.16307795442894646 prot_P49775 + H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate --> 2.0 ADP + 2.0 H+ 0.0 r_0204_REV Ap4A hydrolase (reversible) 0.1607002693067822 prot_P49775 + 2.0 ADP + 2.0 H+ --> H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate 0.0 r_0205 arabinose reductase 0.01001051779935275 prot_P38715 + H+ + L-arabinose + NADPH --> L-arabinitol + NADP(+) 0.0 @@ -311,50 +311,50 @@ r_0211_EXP_2 asparagine synthase (glutamine-hydrolysing) 1.948676097207109 prot_ r_0212 Asparaginyl-tRNA synthetase 1.710863586358636 prot_P38707 + ATP + L-asparagine + tRNA(Asn) --> AMP + Asn-tRNA(Asn) + diphosphate 0.019146806720785902 r_0213 asparaginyl-tRNA synthetase, miotchondrial 1.5617436743674367 prot_P25345 + ATP + L-asparagine + tRNA(Asn) --> AMP + Asn-tRNA(Asn) + diphosphate 0.0 r_0214 aspartate carbamoyltransferase 0.1632300826005862 prot_P07259 + carbamoyl phosphate + L-aspartate --> H+ + N-carbamoyl-L-aspartate + phosphate 0.010726833614579982 -r_0215 aspartate kinase 0.0711086637298091 prot_P10869 + ATP + L-aspartate --> 4-phospho-L-aspartate + ADP 0.0354420994434098 +r_0215 aspartate kinase 0.0711086637298091 prot_P10869 + ATP + L-aspartate --> 4-phospho-L-aspartate + ADP 0.03544209944340982 r_0216 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.0 -r_0216_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.1328188533055378 +r_0216_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.13298799161735828 r_0217 aspartate transaminase 0.021473880597014924 prot_Q01802 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.0 -r_0218 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.0 +r_0218 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.00016913831181727956 r_0218_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.0 -r_0219 aspartate-semialdehyde dehydrogenase 26.415673633916466 prot_P13663 + 4-phospho-L-aspartate + H+ + NADPH --> L-aspartate 4-semialdehyde + NADP(+) + phosphate 0.0354420994434098 +r_0219 aspartate-semialdehyde dehydrogenase 26.415673633916466 prot_P13663 + 4-phospho-L-aspartate + H+ + NADPH --> L-aspartate 4-semialdehyde + NADP(+) + phosphate 0.03544209944340982 r_0220 Aspartyl-tRNA synthetase 0.7351388888888889 prot_P04802 + ATP + L-aspartate + tRNA(Asp) --> AMP + Asp-tRNA(Asp) + diphosphate 0.0240359946744132 r_0221 Aspartyl-tRNA synthetase 0.8733912037037037 prot_P15179 + ATP + L-aspartate + tRNA(Asp) --> AMP + Asp-tRNA(Asp) + diphosphate 0.0 r_0222 ATP adenylyltransferase 0.10660011574074074 prot_P22108 + ADP + ATP + H+ --> P(1),P(4)-bis(5'-adenosyl) tetraphosphate + phosphate 0.0 r_0223 ATP adenylyltransferase 0.10559317129629629 prot_P16550 + ADP + GTP + H+ --> P1-(5'-adenosyl),P4-(5'-guanosyl) tetraphosphate + phosphate 0.0 r_0224 ATP adenylyltransferase 0.10559317129629629 prot_P16550 + GDP + GTP + H+ --> P(1),P(4)-bis(5'-guanosyl) tetraphosphate + phosphate 0.0 r_0225 ATP phosphoribosyltransferase 0.8298868312757202 prot_P00498 + ATP + PRPP --> 5-phosphoribosyl-ATP + diphosphate 0.008356708763266002 -r_0226 ATP synthase 0.5394232482136998 prot_P00830 + 0.09548902616935218 prot_P00854 + 0.019105024583592853 prot_P00856 + 0.08835499603456501 prot_P05626 + 0.5769704298154636 prot_P07251 + 0.07486465662145093 prot_P09457 + 0.022127306899204155 prot_P21306 + 0.06500696272775239 prot_P30902 + 0.11272358287031914 prot_P38077 + 0.25461333861919777 prot_P61829 + 0.0356898398095424 prot_P81449 + 0.021946823156143762 prot_P81450 + 0.024722991276672712 prot_P81451 + 0.03712058366362115 prot_Q06405 + 0.05585151467068882 prot_Q12165 + 0.04240055352878791 prot_Q12233 + 0.04636135130831326 prot_Q12349 + ADP + 3.0 H+ + phosphate --> ATP + 2.0 H+ + H2O 14.400270693517497 +r_0226 ATP synthase 0.028401930104729925 prot_P00830 + 0.005027726661784965 prot_P00854 + 0.0010059254484659976 prot_P00856 + 0.004652102834068531 prot_P05626 + 0.03037887943165331 prot_P07251 + 0.0039418040503784385 prot_P09457 + 0.0011650558740993167 prot_P21306 + 0.0034227727815375154 prot_P30902 + 0.005935167482008843 prot_P38077 + 0.013406004044396558 prot_P61829 + 0.0018791558188794555 prot_P81449 + 0.0011555529713742 prot_P81450 + 0.0013017248932914508 prot_P81451 + 0.0019544879204821996 prot_Q06405 + 0.0029407164432997735 prot_Q12165 + 0.002232491020204252 prot_Q12233 + 0.0024410365400081785 prot_Q12349 + ADP + 3.0 H+ + phosphate --> ATP + 2.0 H+ + H2O 15.15212779596249 r_0226_REV ATP synthase (reversible) 0.3805138888888889 prot_P00830 + 0.06735879629629629 prot_P00854 + 0.013476851851851853 prot_P00856 + 0.06232638888888889 prot_P05626 + 0.407 prot_P07251 + 0.05281018518518518 prot_P09457 + 0.015608796296296296 prot_P21306 + 0.045856481481481484 prot_P30902 + 0.0795162037037037 prot_P38077 + 0.17960648148148148 prot_P61829 + 0.025175925925925925 prot_P81449 + 0.015481481481481481 prot_P81450 + 0.017439814814814814 prot_P81451 + 0.026185185185185186 prot_Q06405 + 0.03939814814814815 prot_Q12165 + 0.029909722222222223 prot_Q12233 + 0.03270370370370371 prot_Q12349 + ATP + 2.0 H+ + H2O --> ADP + 3.0 H+ + phosphate 0.0 r_0227_EXP_1 ATPase, plasma membrane 4.61199074074074 prot_P05030 + 0.20837962962962964 prot_P32903 + 0.22444444444444445 prot_P40975 + ATP + H2O --> ADP + H+ + phosphate 0.0 r_0227_EXP_2 ATPase, plasma membrane 4.730185185185185 prot_P19657 + 0.20837962962962964 prot_P32903 + 0.22444444444444445 prot_P40975 + ATP + H2O --> ADP + H+ + phosphate 0.0 -r_0227_EXP_3 ATPase, plasma membrane 0.023208010335917312 prot_P40009 + ATP + H2O --> ADP + H+ + phosphate 1.818361294058604 +r_0227_EXP_3 ATPase, plasma membrane 0.023208010335917312 prot_P40009 + ATP + H2O --> ADP + H+ + phosphate 1.7941992136988274 r_0228 beta-1,4 mannosyltransferase 63.94951949233543 prot_P16661 + GDP-alpha-D-mannose + N,N'-diacetylchitobiosyldiphosphodolichol --> beta-D-mannosyldiacetylchitobiosyldiphosphodolichol + GDP + H+ 0.0 r_0229 biotin synthase 0.8370103916866507 prot_P32451 + dethiobiotin + polysulphur --> biotin + 2.0 H+ 0.0 r_0229_REV biotin synthase (reversible) 0.8370103916866507 prot_P32451 + biotin + 2.0 H+ --> dethiobiotin + polysulphur 0.0 r_0230 biotin-[acetyl-CoA-carboxylase] ligase 4.713765432098766e-05 prot_P48445 + ATP + biotin + H+ --> biotinyl-5'-AMP + diphosphate 0.0 -r_0231 C-14 sterol reductase 4.194445624507709 prot_P32462 + 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H+ + NADPH --> 14-demethyllanosterol + NADP(+) 0.0037246206773107857 -r_0233 C-22 sterol desaturase (NADP) 100.21895424836602 prot_P54781 + ergosta-5,7,24(28)-trien-3beta-ol + H+ + NADPH + oxygen --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2.0 H2O + NADP(+) 0.0002436024943569164 -r_0234 C-3 sterol dehydrogenase 3.093923129380329 prot_P53199 + NADP(+) + zymosterol intermediate 1c --> carbon dioxide + NADPH + zymosterol intermediate 2 0.0037246206773107857 -r_0235 C-3 sterol dehydrogenase (4-methylzymosterol) 8.806624430682128 prot_P53199 + 4beta-methylzymosterol-4alpha-carboxylic acid + NAD --> 3-dehydro-4-methylzymosterol + carbon dioxide + NADH 0.0037246206773107857 -r_0236 C-3 sterol keto reductase (4-methylzymosterol) 15.116057838660579 prot_Q12452 + 3-dehydro-4-methylzymosterol + H+ + NADPH --> 4alpha-methylzymosterol + NADP(+) 0.003724620677310785 -r_0237 C-3 sterol keto reductase (zymosterol) 15.116057838660579 prot_Q12452 + H+ + NADPH + zymosterol intermediate 2 --> NADP(+) + zymosterol 0.0037246206773107857 -r_0238 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + 4alpha-methylzymosterol + H+ + NADPH + oxygen --> H2O + NADP(+) + zymosterol intermediate 1a 0.0037246206773107857 -r_0239 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + H+ + NADPH + oxygen + zymosterol intermediate 1a --> 2.0 H2O + NADP(+) + zymosterol intermediate 1b 0.0037246206773107857 -r_0240 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + NADPH + oxygen + zymosterol intermediate 1b --> H2O + NADP(+) + zymosterol intermediate 1c 0.0037246206773107857 -r_0241 C-4 sterol methyl oxidase (4,4-dimethylzymosterol) 0.511770482603816 prot_P53045 + 14-demethyllanosterol + 5.0 H+ + 3.0 oxygen + 6.0 ferrocytochrome b5 --> 4beta-methylzymosterol-4alpha-carboxylic acid + 4.0 H2O + 6.0 ferricytochrome b5 0.0037246206773107857 -r_0242 C-5 sterol desaturase 24.953439493862604 prot_P32353 + episterol + H+ + NADPH + oxygen --> ergosta-5,7,24(28)-trien-3beta-ol + 2.0 H2O + NADP(+) 0.00024360249435691642 -r_0243 C-8 sterol isomerase 11.181301444435384 prot_P32352 + fecosterol --> episterol 0.00024360249435691642 +r_0231 C-14 sterol reductase 4.194445624507709 prot_P32462 + 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H+ + NADPH --> 14-demethyllanosterol + NADP(+) 0.003687743244862164 +r_0233 C-22 sterol desaturase (NADP) 100.21895424836602 prot_P54781 + ergosta-5,7,24(28)-trien-3beta-ol + H+ + NADPH + oxygen --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2.0 H2O + NADP(+) 0.0 +r_0234 C-3 sterol dehydrogenase 3.093923129380329 prot_P53199 + NADP(+) + zymosterol intermediate 1c --> carbon dioxide + NADPH + zymosterol intermediate 2 0.003687743244862164 +r_0235 C-3 sterol dehydrogenase (4-methylzymosterol) 8.806624430682128 prot_P53199 + 4beta-methylzymosterol-4alpha-carboxylic acid + NAD --> 3-dehydro-4-methylzymosterol + carbon dioxide + NADH 0.003687743244862164 +r_0236 C-3 sterol keto reductase (4-methylzymosterol) 15.116057838660579 prot_Q12452 + 3-dehydro-4-methylzymosterol + H+ + NADPH --> 4alpha-methylzymosterol + NADP(+) 0.003687743244862164 +r_0237 C-3 sterol keto reductase (zymosterol) 15.116057838660579 prot_Q12452 + H+ + NADPH + zymosterol intermediate 2 --> NADP(+) + zymosterol 0.003687743244862164 +r_0238 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + 4alpha-methylzymosterol + H+ + NADPH + oxygen --> H2O + NADP(+) + zymosterol intermediate 1a 0.003687743244862164 +r_0239 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + H+ + NADPH + oxygen + zymosterol intermediate 1a --> 2.0 H2O + NADP(+) + zymosterol intermediate 1b 0.003687743244862164 +r_0240 C-4 methyl sterol oxidase 0.511770482603816 prot_P53045 + NADPH + oxygen + zymosterol intermediate 1b --> H2O + NADP(+) + zymosterol intermediate 1c 0.003687743244862164 +r_0241 C-4 sterol methyl oxidase (4,4-dimethylzymosterol) 0.511770482603816 prot_P53045 + 14-demethyllanosterol + 5.0 H+ + 3.0 oxygen + 6.0 ferrocytochrome b5 --> 4beta-methylzymosterol-4alpha-carboxylic acid + 4.0 H2O + 6.0 ferricytochrome b5 0.003687743244862164 +r_0242 C-5 sterol desaturase 24.953439493862604 prot_P32353 + episterol + H+ + NADPH + oxygen --> ergosta-5,7,24(28)-trien-3beta-ol + 2.0 H2O + NADP(+) 0.0 +r_0243 C-8 sterol isomerase 11.181301444435384 prot_P32352 + fecosterol --> episterol 0.0 r_0244 C-s24 sterol reductase 1.5624148864343401 prot_P25340 + ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + NADPH --> ergosterol + NADP(+) 0.003687743244862164 r_0249 CAAX farnesyltransferase 4.1518225763666585 prot_P22007 + 3.231511956720494 prot_P29703 + 4-hydroxybenzoate + nonaprenyl diphosphate --> diphosphate + nonaprenyl 4-hydroxybenzoate 0.0 -r_0250_EXP_1 carbamoyl-phosphate synthase (glutamine-hydrolysing) 0.01089245390373571 prot_P07259 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.17339351088864613 +r_0250_EXP_1 carbamoyl-phosphate synthase (glutamine-hydrolysing) 0.01089245390373571 prot_P07259 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.19728585628504738 r_0250_EXP_2 carbamoyl-phosphate synthase (glutamine-hydrolysing) 3.661790780141844 prot_P03965 + 1.34048463356974 prot_P07258 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.0 r_0252_EXP_1 carnitine O-acetyltransferase 0.016201655041376033 prot_P80235 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 r_0252_EXP_2 carnitine O-acetyltransferase 0.05053501564945227 prot_P40017 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 -r_0253 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.007861388341728892 -r_0254 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + coenzyme A + O-acetylcarnitine --> (R)-carnitine + acetyl-CoA 0.007861388341728892 -r_0255 catalase 6.339124460149195e-06 prot_P06115 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0 -r_0256 catalase 5.747447978013349e-06 prot_P15202 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0 +r_0253 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0013531064945376536 +r_0254 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + coenzyme A + O-acetylcarnitine --> (R)-carnitine + acetyl-CoA 0.0013531064945376536 +r_0255 catalase 6.339124460149195e-06 prot_P06115 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0006148755121651877 +r_0256 catalase 5.747447978013349e-06 prot_P15202 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0005919840913604785 r_0259 ceramide-1 hydroxylase (24C) 0.035359375 prot_P38992 + ceramide-1 (C24) + H+ + NADPH + oxygen --> ceramide-2 (C24) + H2O + NADP(+) 0.0 r_0260 ceramide-1 hydroxylase (24C) 0.03895920138888889 prot_Q03529 + ceramide-1 (C24) + H+ + NADPH + oxygen --> ceramide-2' (C24) + H2O + NADP(+) 0.0 r_0261 ceramide-1 hydroxylase (26C) 93.24819642235255 prot_P38992 + ceramide-1 (C26) + H+ + NADPH + oxygen --> ceramide-2 (C26) + H2O + NADP(+) 0.0 @@ -363,20 +363,20 @@ r_0263 ceramide-1 synthase (24C) 2.14331629947548 prot_P28496 + 2.11982346691468 r_0264 ceramide-1 synthase (26C) 2.14331629947548 prot_P28496 + 2.1198234669146876 prot_P38703 + 1.505553705301869 prot_Q03579 + hexacosanoyl-CoA + sphinganine --> ceramide-1 (C26) + coenzyme A + H+ 0.0 r_0265 ceramide-2 synthase (24C) 2.14331629947548 prot_P28496 + 2.1198234669146876 prot_P38703 + 1.505553705301869 prot_Q03579 + phytosphingosine + tetracosanoyl-CoA --> ceramide-2 (C24) + coenzyme A + H+ 0.0 r_0266 ceramide-2 synthase (26C) 2.14331629947548 prot_P28496 + 2.1198234669146876 prot_P38703 + 1.505553705301869 prot_Q03579 + hexacosanoyl-CoA + phytosphingosine --> ceramide-2 (C26) + coenzyme A + H+ 0.0 -r_0267 ceramide-3 synthase (24C) 33.46082510731026 prot_Q03529 + ceramide-2 (C24) + H+ + NADPH + oxygen --> ceramide-3 (C24) + H2O + NADP(+) 0.0 +r_0267 ceramide-3 synthase (24C) 33.46082510731026 prot_Q03529 + ceramide-2 (C24) + H+ + NADPH + oxygen --> ceramide-3 (C24) + H2O + NADP(+) 3.1223690629427635e-13 r_0268 ceramide-3 synthase (26C) 33.46082510731026 prot_Q03529 + ceramide-2 (C26) + H+ + NADPH + oxygen --> ceramide-3 (C26) + H2O + NADP(+) 0.0 -r_0269 ceramide-4 synthase (24C) 33.46082510731026 prot_Q03529 + ceramide-3 (C24) + H+ + NADPH + oxygen --> ceramide-4 (C24) + H2O + NADP(+) 0.0 +r_0269 ceramide-4 synthase (24C) 33.46082510731026 prot_Q03529 + ceramide-3 (C24) + H+ + NADPH + oxygen --> ceramide-4 (C24) + H2O + NADP(+) 3.1223690629427635e-13 r_0270 ceramide-4 synthase (26C) 33.46082510731026 prot_Q03529 + ceramide-3 (C26) + H+ + NADPH + oxygen --> ceramide-4 (C26) + H2O + NADP(+) 0.0 r_0271_EXP_1 chitin deacetylase 0.017415216320292786 prot_Q06702 + chitin + H2O --> acetate + chitosan + H+ 0.0 r_0271_EXP_2 chitin deacetylase 0.01794357473933983 prot_Q06703 + chitin + H2O --> acetate + chitosan + H+ 0.0 r_0272_EXP_1 chitin synthase 80.72709323101475 prot_P29465 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0 r_0272_EXP_2 chitin synthase 13.190119547029806 prot_P14180 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0023610000000000003 r_0272_EXP_3 chitin synthase 188.53265572369114 prot_P08004 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0 -r_0273 choline kinase 7.224074074074074 prot_P20485 + ATP + choline --> ADP + choline phosphate + H+ 0.0036216614989950545 -r_0274 choline phosphate cytididyltransferase 0.4121287954621288 prot_P13259 + choline phosphate + CTP + H+ --> CDP-choline + diphosphate 0.0036216614989950545 -r_0278 chorismate mutase 0.02288935056940597 prot_P32178 + chorismate --> prephenate 0.07162420590641712 -r_0279 chorismate synthase 0.3336437908496732 prot_P28777 + 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid --> chorismate + phosphate 0.07609464734991835 -r_0280 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.0 +r_0273 choline kinase 7.224074074074074 prot_P20485 + ATP + choline --> ADP + choline phosphate + H+ 0.0036216614996331946 +r_0274 choline phosphate cytididyltransferase 0.4121287954621288 prot_P13259 + choline phosphate + CTP + H+ --> CDP-choline + diphosphate 0.0036216614996331946 +r_0278 chorismate mutase 0.02288935056940597 prot_P32178 + chorismate --> prephenate 0.0289821618819572 +r_0279 chorismate synthase 0.3336437908496732 prot_P28777 + 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid --> chorismate + phosphate 0.033452483325451324 +r_0280 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.8542185899886353 r_0280_REV cis-aconitate(3-) to isocitrate (reversible) 0.16582750582750583 prot_P19414 + isocitrate --> cis-aconitate + H2O 0.0 r_0281_EXP_1 cis-prenyltransferase step 01 40.954572225982666 prot_P35196 + farnesyl diphosphate + isopentenyl diphosphate --> diphosphate + geranylgeranyl diphosphate 0.0 r_0281_EXP_2 cis-prenyltransferase step 01 30.078354060470264 prot_Q03175 + farnesyl diphosphate + isopentenyl diphosphate --> diphosphate + geranylgeranyl diphosphate 0.0 @@ -420,28 +420,28 @@ r_0298_EXP_1 cis-prenyltransferase step 18 40.954572225982666 prot_P35196 + icos r_0298_EXP_2 cis-prenyltransferase step 18 30.078354060470264 prot_Q03175 + icosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + henicosaprenyl diphosphate 0.0 r_0299_EXP_1 cis-prenyltransferase step 19 40.954572225982666 prot_P35196 + henicosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + docosaprenyl diphosphate 0.0 r_0299_EXP_2 cis-prenyltransferase step 19 30.078354060470264 prot_Q03175 + henicosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + docosaprenyl diphosphate 0.0 -r_0300_EXP_1 citrate synthase 0.10489895415585436 prot_P00890 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 1.6450625360586744 +r_0300_EXP_1 citrate synthase 0.10489895415585436 prot_P00890 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 1.6797958985578814 r_0300_EXP_2 citrate synthase 0.10578556263269638 prot_P43635 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.0 r_0301 citrate synthase, peroxisomal 1.275124007936508 prot_P08679 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.0 -r_0302 citrate to cis-aconitate(3-) 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.0 +r_0302 citrate to cis-aconitate(3-) 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.8542185899886353 r_0302_REV citrate to cis-aconitate(3-) (reversible) 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> citrate 0.0 -r_0303 citrate to cis-aconitate(3-), cytoplasmic 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 1.6450625360586744 +r_0303 citrate to cis-aconitate(3-), cytoplasmic 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.8255773085692462 r_0303_REV citrate to cis-aconitate(3-), cytoplasmic (reversible) 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> citrate 0.0 r_0304 coproporphyrinogen oxidase (O2 required) 616.2091503267974 prot_P11353 + coproporphyrinogen III + 2.0 H+ + oxygen --> 2.0 carbon dioxide + 2.0 H2O + protoporphyrinogen 0.0 r_0306_EXP_1 CTP synthase (glutamine) 0.5634796238244514 prot_P28274 + ATP + H2O + L-glutamine + UTP --> ADP + CTP + 2.0 H+ + L-glutamate + phosphate 0.0 r_0306_EXP_2 CTP synthase (glutamine) 0.5617467781260884 prot_P38627 + ATP + H2O + L-glutamine + UTP --> ADP + CTP + 2.0 H+ + L-glutamate + phosphate 0.0 r_0307_EXP_1 CTP synthase (NH3) 0.5634796238244514 prot_P28274 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.0 -r_0307_EXP_2 CTP synthase (NH3) 0.5617467781260884 prot_P38627 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.004327623918448701 +r_0307_EXP_2 CTP synthase (NH3) 0.5617467781260884 prot_P38627 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.004327623918448702 r_0308_EXP_1 cystathionine b-lyase 11.285409035409035 prot_P43623 + H2O + L-cystathionine --> ammonium + L-homocysteine + pyruvate 0.0 r_0308_EXP_2 cystathionine b-lyase 15.820512820512821 prot_P53101 + H2O + L-cystathionine --> ammonium + L-homocysteine + pyruvate 0.0 -r_0309 cystathionine beta-synthase 0.7237984496124031 prot_P32582 + L-homocysteine + L-serine --> H2O + L-cystathionine 0.0037750499662955288 -r_0310 cystathionine g-lyase 6.5288520564763655 prot_P31373 + H2O + L-cystathionine --> 2-oxobutanoate + ammonium + L-cysteine 0.0037750499662955288 +r_0309 cystathionine beta-synthase 0.7237984496124031 prot_P32582 + L-homocysteine + L-serine --> H2O + L-cystathionine 0.0037750499662955565 +r_0310 cystathionine g-lyase 6.5288520564763655 prot_P31373 + H2O + L-cystathionine --> 2-oxobutanoate + ammonium + L-cysteine 0.0037750499662955565 r_0311 cystathionine gamma-synthase 0.16609504132231406 prot_P47164 + L-cysteine + O-acetyl-L-homoserine --> acetate + H+ + L-cystathionine 0.0 r_0312 cysteine synthase 0.05827586206896552 prot_P06106 + hydrogen sulfide + O-acetyl-L-serine --> acetate + L-cysteine 0.0 r_0313 cysteinyl-tRNA synthetase 0.1712245696400626 prot_P53852 + ATP + L-cysteine + tRNA(Cys) --> AMP + Cys-tRNA(Cys) + diphosphate 0.00375594996568427 r_0314 cytidine deaminase 0.34727251593751957 prot_Q06549 + cytidine + H+ + H2O --> ammonium + uridine 0.0 r_0315 cytidine kinase (GTP) 3.6366925064599482 prot_P27515 + cytidine + GTP --> CMP + GDP + H+ 0.0 -r_0317 cytochrome P450 lanosterol 14-alpha-demethylase (NADP) 2.53 prot_P10614 + 3.1988333333333334 prot_P16603 + 2.0 H+ + lanosterol + 3.0 NADPH + 3.0 oxygen --> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 4.0 H2O + 3.0 NADP(+) 0.0037246206773107857 +r_0317 cytochrome P450 lanosterol 14-alpha-demethylase (NADP) 2.53 prot_P10614 + 3.1988333333333334 prot_P16603 + 2.0 H+ + lanosterol + 3.0 NADPH + 3.0 oxygen --> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 4.0 H2O + 3.0 NADP(+) 0.003687743244862164 r_0318 cytosine deaminase 0.028606209150326797 prot_Q12178 + cytosine + H+ + H2O --> ammonium + uracil 0.0 r_0319 D-arabinono-1,4-lactone oxidase 0.790723019670388 prot_P54783 + D-arabinono-1,4-lactone + oxygen --> dehydro-D-arabinono-1,4-lactone + H+ + hydrogen peroxide 0.0 r_0320 D-arabinose 1-dehydrogenase (NAD) 4.371122252366052 prot_Q04212 + D-arabinose + NAD --> D-arabinono-1,4-lactone + H+ + NADH 0.0 @@ -459,7 +459,7 @@ r_0330 deoxyguanylate kinase (dGMP:ATP) 0.06369444444444444 prot_P15454 + ATP + r_0330_REV deoxyguanylate kinase (dGMP:ATP) (reversible) 0.014549492385786802 prot_P15454 + ADP + dGDP --> ATP + dGMP 0.00024000001139938803 r_0331 deoxyhypusine synthase, cytosolic/mitochondrial 66.19135802469135 prot_P38791 + H2O + spermidine + ubiquinone-6 --> 4-aminobutanal + trimethylenediamine + ubiquinol-6 0.0 r_0332 deoxyribokinase 0.214529735759604 prot_P25332 + 2-deoxy-D-ribose + ATP --> 2-deoxy-D-ribose 5-phosphate + ADP + H+ 0.0 -r_0334 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 7.48783658670619e-05 +r_0334 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 8.415391074551606e-05 r_0335 dethiobiotin synthase 0.18895365572826714 prot_P53630 + 7,8-diaminononanoate + ATP + carbon dioxide --> ADP + dethiobiotin + 3.0 H+ + phosphate 0.0 r_0335_REV dethiobiotin synthase (reversible) 0.14884920634920634 prot_P53630 + ADP + dethiobiotin + 3.0 H+ + phosphate --> 7,8-diaminononanoate + ATP + carbon dioxide 0.0 r_0340 dihydroceramidase 2.6755547192301745 prot_Q02896 + lignoceric acid + sphinganine --> ceramide-1 (C24) + H2O 0.0 @@ -468,20 +468,20 @@ r_0341 dihydroceramidase 2.6755547192301745 prot_Q02896 + cerotic acid + sphinga r_0341_REV dihydroceramidase (reversible) 64.05862892989363 prot_Q02896 + ceramide-1 (C26) + H2O --> cerotic acid + sphinganine 0.0 r_0342 dihydroceramidase 31.281410816343165 prot_Q02896 + ceramide-2 (C24) + H2O --> lignoceric acid + phytosphingosine 0.0 r_0343 dihydroceramidase 31.281410816343165 prot_Q02896 + ceramide-2 (C26) + H2O --> cerotic acid + phytosphingosine 0.0 -r_0344 dihydrofolate reductase 0.030913608562691132 prot_P07807 + dihydrofolic acid + H+ + NADPH --> NADP(+) + THF 0.0003663399940705285 +r_0344 dihydrofolate reductase 0.030913608562691132 prot_P07807 + dihydrofolic acid + H+ + NADPH --> NADP(+) + THF 0.00036633999407064126 r_0345 dihydrofolate reductase 0.030913608562691132 prot_P07807 + dihydrofolic acid + H+ + NADPH --> NADP(+) + THF 0.0 -r_0346 dihydrofolate synthase 1.4510179534077177 prot_Q12676 + 7,8-dihydropteroate + ATP + L-glutamate --> ADP + dihydrofolic acid + H+ + phosphate 6.340000254510467e-06 -r_0347 dihydroneopterin aldolase 25.866666666666667 prot_P53848 + 7,8-dihydroneopterin --> 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + glycolaldehyde 6.340000254510467e-06 +r_0346 dihydrofolate synthase 1.4510179534077177 prot_Q12676 + 7,8-dihydropteroate + ATP + L-glutamate --> ADP + dihydrofolic acid + H+ + phosphate 6.340000254623224e-06 +r_0347 dihydroneopterin aldolase 25.866666666666667 prot_P53848 + 7,8-dihydroneopterin --> 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + glycolaldehyde 6.340000254623224e-06 r_0348 dihydroneopterin monophosphate dephosphorylase 1.3136097495034373 prot_Q12154 + 7,8-dihydroneopterin 3'-phosphate + H2O --> 7,8-dihydroneopterin + phosphate 0.0 r_0349 dihydroorotase 5.893713450292398 prot_P20051 + (S)-dihydroorotate + H2O --> H+ + N-carbamoyl-L-aspartate 0.0 r_0349_REV dihydroorotase (reversible) 0.17974406991260924 prot_P20051 + H+ + N-carbamoyl-L-aspartate --> (S)-dihydroorotate + H2O 0.010726833614579982 r_0350 dihydropteroate synthase 237.30886850152908 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + 4-aminobenzoate --> 7,8-dihydropteroate + H2O 0.0 -r_0351 dihydropteroate synthase 237.30886850152908 prot_P53848 + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + 4-aminobenzoate --> 7,8-dihydropteroate + diphosphate 6.340000254510467e-06 -r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.23036133098798006 prot_P39522 + (R)-2,3-dihydroxy-3-methylbutanoate --> 3-methyl-2-oxobutanoate + H2O 0.2697092880520629 +r_0351 dihydropteroate synthase 237.30886850152908 prot_P53848 + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + 4-aminobenzoate --> 7,8-dihydropteroate + diphosphate 6.340000254623224e-06 +r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.23036133098798006 prot_P39522 + (R)-2,3-dihydroxy-3-methylbutanoate --> 3-methyl-2-oxobutanoate + H2O 0.2529039502352728 r_0353 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate) 1.419625112917796 prot_P39522 + (2R,3R)-2,3-dihydroxy-3-methylpentanoate --> (S)-3-methyl-2-oxopentanoate + H2O 0.0265490320174191 r_0354_EXP_1 dihydroxyacetone kinase 0.7185562956795263 prot_P43550 + ATP + glycerone --> ADP + dihydroxyacetone phosphate + H+ 0.0 r_0354_EXP_2 dihydroxyacetone kinase 0.719388935146637 prot_P54838 + ATP + glycerone --> ADP + dihydroxyacetone phosphate + H+ 0.0 -r_0355 dimethylallyltranstransferase 10.222979797979797 prot_P08524 + isopentenyl diphosphate + prenyl diphosphate(3-) --> diphosphate + geranyl diphosphate 0.007449241354621576 +r_0355 dimethylallyltranstransferase 10.222979797979797 prot_P08524 + isopentenyl diphosphate + prenyl diphosphate(3-) --> diphosphate + geranyl diphosphate 0.007375486489724328 r_0356 diphosphoglyceromutase 0.013314525462962964 prot_P00950 + 1,3-bisphospho-D-glycerate --> 2,3-bisphospho-D-glyceric acid + H+ 0.0 r_0356_REV diphosphoglyceromutase (reversible) 0.013314525462962964 prot_P00950 + 2,3-bisphospho-D-glyceric acid + H+ --> 1,3-bisphospho-D-glycerate 0.0 r_0357 diphosphoinositol-1,3,4,6-tetrakisphosphate diphosphohydrolase 2396.8888888888887 prot_Q99321 + 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + 3.0 H2O --> 3.0 H+ + myo-inositol 1,3,4,5,6-pentakisphosphate + 3.0 phosphate 0.0 @@ -498,7 +498,7 @@ r_0364_EXP_1 dUTP diphosphatase 0.006082204603017289 prot_P47119 + dUTP + H2O -- r_0364_EXP_2 dUTP diphosphatase 0.4429108796296296 prot_P33317 + dUTP + H2O --> diphosphate + dUMP + H+ 0.0 r_0365 endopolygalacturonase 1.7035361842105263 prot_P47180 + H2O + pectin --> D-galacturonate 0.0 r_0366_EXP_1 enolase 0.05715942028985507 prot_P0CX11 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 -r_0366_EXP_2 enolase 0.056541062801932364 prot_P00924 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 5.676642926896894 +r_0366_EXP_2 enolase 0.056541062801932364 prot_P00924 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 5.710314963956096 r_0366_EXP_3 enolase 0.18354460093896713 prot_P00925 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 r_0366_EXP_4 enolase 0.057141304347826084 prot_P42222 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 r_0366_EXP_5 enolase 0.05715942028985507 prot_P0CX10 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 @@ -529,30 +529,30 @@ r_0412_REV fatty-acid--CoA ligase (tetradecanoate) (reversible) 33.7398594538402 r_0436 ferrochelatase 8.096586782861293 prot_P16622 + iron(2+) + protoporphyrin --> ferroheme b + 2.0 H+ 0.0 r_0437_EXP_1 ferrocytochrome-c:hydrogen-peroxide oxidoreductase 0.003481111111111111 prot_P00045 + 0.011209166666666666 prot_P00431 + 2.0 ferrocytochrome c + hydrogen peroxide --> 2.0 ferricytochrome c + 2.0 H2O 0.0 r_0437_EXP_2 ferrocytochrome-c:hydrogen-peroxide oxidoreductase 0.003383888888888889 prot_P00044 + 0.011209166666666666 prot_P00431 + 2.0 ferrocytochrome c + hydrogen peroxide --> 2.0 ferricytochrome c + 2.0 H2O 0.0 -r_0438_EXP_1 ferrocytochrome-c:oxygen oxidoreductase 0.0025292407050374562 prot_P00045 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003470743090051798 prot_P00425 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_2 ferrocytochrome-c:oxygen oxidoreductase 0.0025292407050374562 prot_P00045 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003459239202389243 prot_P00424 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_3 ferrocytochrome-c:oxygen oxidoreductase 0.002458602798337559 prot_P00044 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003470743090051798 prot_P00425 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_4 ferrocytochrome-c:oxygen oxidoreductase 0.002458602798337559 prot_P00044 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003459239202389243 prot_P00424 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 11.233635451922437 -r_0438_EXP_5 ferrocytochrome-c:oxygen oxidoreductase 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.0014052906981468086 prot_P07255 + 0.006870848273403699 prot_P19516 + 0.003495163623510905 prot_P38824 + 0.0028410566074698585 prot_P47081 + 0.007194975353860941 prot_P53239 + 0.004794901106789011 prot_Q04935 + 0.0022412398682924474 prot_Q3E731 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 12.663294032469631 -r_0439_EXP_1 ubiquinol:ferricytochrome c reductase 0.011983406387337664 prot_P00045 + 0.01650156750927913 prot_P00127 + 0.013927410950492583 prot_P00128 + 0.041744940093010934 prot_P00163 + 0.03256422793814109 prot_P07143 + 0.04802924800695788 prot_P07256 + 0.03870605839025327 prot_P07257 + 0.022342187219928544 prot_P08067 + 0.010494564722393141 prot_P08525 + 0.007148734930716276 prot_P22289 + 0.008216837782188999 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 3.221166511132227 -r_0439_EXP_2 ubiquinol:ferricytochrome c reductase 0.01164872778571237 prot_P00044 + 0.01650156750927913 prot_P00127 + 0.013927410950492583 prot_P00128 + 0.041744940093010934 prot_P00163 + 0.03256422793814109 prot_P07143 + 0.04802924800695788 prot_P07256 + 0.03870605839025327 prot_P07257 + 0.022342187219928544 prot_P08067 + 0.010494564722393141 prot_P08525 + 0.007148734930716276 prot_P22289 + 0.008216837782188999 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 8.706943193300212 +r_0438_EXP_1 ferrocytochrome-c:oxygen oxidoreductase 0.0010737358074137757 prot_P00045 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0014734307915811285 prot_P00425 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_2 ferrocytochrome-c:oxygen oxidoreductase 0.0010737358074137757 prot_P00045 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.001468547058655611 prot_P00424 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_3 ferrocytochrome-c:oxygen oxidoreductase 0.0010437479736605981 prot_P00044 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0014734307915811285 prot_P00425 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_4 ferrocytochrome-c:oxygen oxidoreductase 0.0010437479736605981 prot_P00044 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.001468547058655611 prot_P00424 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 24.282943884694998 +r_0438_EXP_5 ferrocytochrome-c:oxygen oxidoreductase 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0005965865326382158 prot_P07255 + 0.0029168737494090794 prot_P19516 + 0.001483798014107227 prot_P38824 + 0.0012061106735528025 prot_P47081 + 0.00305447506657366 prot_P53239 + 0.0020355741551656946 prot_Q04935 + 0.0009514711252258203 prot_Q3E731 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0439_EXP_1 ubiquinol:ferricytochrome c reductase 0.0023972378816698543 prot_P00045 + 0.003301079965207204 prot_P00127 + 0.002786129089253226 prot_P00128 + 0.00835092698389556 prot_P00163 + 0.006514358128013637 prot_P07143 + 0.009608080459664334 prot_P07256 + 0.007743009493634883 prot_P07257 + 0.004469475191925961 prot_P08067 + 0.0020994003950946896 prot_P08525 + 0.0014300790299524282 prot_P22289 + 0.001643749211393956 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 0.0 +r_0439_EXP_2 ubiquinol:ferricytochrome c reductase 0.002330286616222643 prot_P00044 + 0.003301079965207204 prot_P00127 + 0.002786129089253226 prot_P00128 + 0.00835092698389556 prot_P00163 + 0.006514358128013637 prot_P07143 + 0.009608080459664334 prot_P07256 + 0.007743009493634883 prot_P07257 + 0.004469475191925961 prot_P08067 + 0.0020994003950946896 prot_P08525 + 0.0014300790299524282 prot_P22289 + 0.001643749211393956 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 12.09796960037607 r_0440 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 9.99999974737875e-07 r_0441 FMN reductase 0.10556051587301588 prot_Q07923 + FMN + 2.0 H+ + NADH --> FMNH2 + NAD 0.0 r_0442 FMN reductase 0.10556051587301588 prot_Q07923 + FMN + 2.0 H+ + NADPH --> FMNH2 + NADP(+) 0.0 r_0443 formaldehyde dehydrogenase 8.906684027777779 prot_P32771 + formaldehyde + glutathione + NAD --> H+ + NADH + S-formylglutathione 0.0 r_0445 formate dehydrogenase 0.012874691358024692 prot_Q08911 + formate + NAD --> carbon dioxide + NADH 0.0 r_0446 formate-tetrahydrofolate ligase 0.3982132433666004 prot_P07245 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.0 -r_0446_REV formate-tetrahydrofolate ligase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.4353783214949426 +r_0446_REV formate-tetrahydrofolate ligase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.4354151989273829 r_0447 formate-tetrahydrofolate ligase 0.42978473739580797 prot_P09440 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.0 r_0447_REV formate-tetrahydrofolate ligase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.0 r_0448_EXP_1 fructose-2,6-bisphosphate 2-phosphatase 5.915698747876994 prot_Q06137 + beta-D-fructose 2,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 r_0448_EXP_2 fructose-2,6-bisphosphate 2-phosphatase 146.09722222222223 prot_P32604 + beta-D-fructose 2,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 r_0449 fructose-bisphosphatase 0.15249083373186673 prot_P09201 + D-fructose 1,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 -r_0450 fructose-bisphosphate aldolase 0.166213415970673 prot_P14540 + D-fructose 1,6-bisphosphate --> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate 3.2011841721513563 +r_0450 fructose-bisphosphate aldolase 0.166213415970673 prot_P14540 + D-fructose 1,6-bisphosphate --> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate 3.2153982268262493 r_0450_REV fructose-bisphosphate aldolase (reversible) 0.33864102564102566 prot_P14540 + dihydroxyacetone phosphate + glyceraldehyde 3-phosphate --> D-fructose 1,6-bisphosphate 0.0 -r_0451 fumarase 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 1.4886028704009004 +r_0451 fumarase 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 1.5233269573552595 r_0451_REV fumarase (reversible) 0.014265163714439076 prot_P08417 + (S)-malate --> fumarate + H2O 0.0 -r_0452 fumarase, cytoplasmic 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.10567194258696651 +r_0452 fumarase, cytoplasmic 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.06302989856250976 r_0452_REV fumarase, cytoplasmic (reversible) 0.014265163714439076 prot_P08417 + (S)-malate --> fumarate + H2O 0.0 r_0453 dihydoorotic acid dehydrogenase 1.1372875816993464 prot_P28272 + (S)-dihydroorotate + fumarate --> orotate + succinate 0.010726833614579982 r_0454 fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.0 @@ -562,45 +562,45 @@ r_0455_REV soluble fumarate reductase (reversible) 0.9170995670995671 prot_P3261 r_0457 g-glutamyltransferase 17.374169040835707 prot_Q05902 + glutathione + L-alanine --> L-cysteinylglycine + L-gamma-glutamyl-L-alanine 0.0 r_0458 galactokinase 0.7217737917289487 prot_P04385 + ATP + D-galactose --> ADP + alpha-D-galactose 1-phosphate + H+ 0.0 r_0459 galactose-1-phosphate uridylyltransferase 0.3270447530864197 prot_P08431 + alpha-D-galactose 1-phosphate + H+ + UTP --> diphosphate + UDP-D-galactose 0.0 -r_0460 gamma-glutamylcysteine synthetase 0.00213319158216116 prot_P32477 + ATP + L-cysteine + L-glutamate --> ADP + H+ + L-gamma-glutamyl-L-cysteine + phosphate 9.999999999940612e-08 +r_0460 gamma-glutamylcysteine synthetase 0.00213319158216116 prot_P32477 + ATP + L-cysteine + L-glutamate --> ADP + H+ + L-gamma-glutamyl-L-cysteine + phosphate 1e-07 r_0461 geranylgeranyltranstransferase 0.6162073031087573 prot_standard + geranylgeranyl diphosphate + isopentenyl diphosphate --> diphosphate + pentaprenyl diphosphate 0.0 -r_0462 geranyltranstransferase 10.222979797979797 prot_P08524 + geranyl diphosphate + isopentenyl diphosphate --> farnesyl diphosphate + diphosphate 0.007449241354621577 +r_0462 geranyltranstransferase 10.222979797979797 prot_P08524 + geranyl diphosphate + isopentenyl diphosphate --> farnesyl diphosphate + diphosphate 0.007375486489724328 r_0463 glucan 1,4-alpha-glucosidase 44.78465926163774 prot_Q06625 + glycogen + H2O --> D-glucose 0.0 r_0464 glucan 1,4-alpha-glucosidase, vacuole 0.05205199864498645 prot_P08019 + glycogen + H2O --> D-glucose 0.0 r_0465 glucosamine-6-phosphate deaminase 0.1225001911377612 prot_standard + alpha-D-glucosamine 6-phosphate + H2O --> ammonium + D-fructose 6-phosphate 0.0 -r_0466 glucose 6-phosphate dehydrogenase 0.025250210703750525 prot_P11412 + D-glucose 6-phosphate + NADP(+) --> 6-O-phosphono-D-glucono-1,5-lactone + H+ + NADPH 2.2864587827242655e-13 -r_0467 glucose-6-phosphate isomerase 0.024857664233576642 prot_P12709 + D-glucose 6-phosphate --> D-fructose 6-phosphate 3.3230270286256616 +r_0466 glucose 6-phosphate dehydrogenase 0.025250210703750525 prot_P11412 + D-glucose 6-phosphate + NADP(+) --> 6-O-phosphono-D-glucono-1,5-lactone + H+ + NADPH 0.0 +r_0467 glucose-6-phosphate isomerase 0.024857664233576642 prot_P12709 + D-glucose 6-phosphate --> D-fructose 6-phosphate 3.323027028625889 r_0467_REV glucose-6-phosphate isomerase (reversible) 0.024857664233576642 prot_P12709 + D-fructose 6-phosphate --> D-glucose 6-phosphate 0.0 -r_0468 glutamate 5-kinase 1.0234809027777778 prot_P32264 + ATP + L-glutamate --> ADP + L-gamma-glutamyl phosphate 0.005618824771525774 -r_0469 glutamate decarboxylase 34.13511276639768 prot_Q04792 + H+ + L-glutamate --> carbon dioxide + gamma-aminobutyrate 0.0 +r_0468 glutamate 5-kinase 1.0234809027777778 prot_P32264 + ATP + L-glutamate --> ADP + L-gamma-glutamyl phosphate 0.005618824771525775 +r_0469 glutamate decarboxylase 34.13511276639768 prot_Q04792 + H+ + L-glutamate --> carbon dioxide + gamma-aminobutyrate 0.00022698358235192915 r_0470 glutamate dehydrogenase (NAD) 1.4390277777777778 prot_P33327 + H2O + L-glutamate + NAD --> 2-oxoglutarate + ammonium + H+ + NADH 0.0 r_0471_EXP_1 glutamate dehydrogenase (NADP) 0.5307169380898228 prot_P39708 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.0 -r_0471_EXP_2 glutamate dehydrogenase (NADP) 0.5301073734280234 prot_P07262 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.9932526095313009 +r_0471_EXP_2 glutamate dehydrogenase (NADP) 0.5301073734280234 prot_P07262 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.9932894869635238 r_0472 glutamate synthase (NADH2) 0.9448492063492063 prot_Q12680 + 2-oxoglutarate + H+ + L-glutamine + NADH --> 2.0 L-glutamate + NAD 0.0 -r_0473 glutamate-5-semialdehyde dehydrogenase 0.2646166013940106 prot_P54885 + H+ + L-gamma-glutamyl phosphate + NADPH --> L-glutamic 5-semialdehyde + NADP(+) + phosphate 0.005618824771525774 +r_0473 glutamate-5-semialdehyde dehydrogenase 0.2646166013940106 prot_P54885 + H+ + L-gamma-glutamyl phosphate + NADPH --> L-glutamic 5-semialdehyde + NADP(+) + phosphate 0.005618824771525775 r_0475_EXP_1 glutaminase 0.0011171565228214292 prot_P43544 + H2O + L-glutamine --> ammonium + L-glutamate 0.0 r_0475_EXP_2 glutaminase 0.0011205348411301363 prot_P53823 + H2O + L-glutamine --> ammonium + L-glutamate 0.0 -r_0476 glutamine synthetase 0.029297138047138047 prot_P32288 + ammonium + ATP + L-glutamate --> ADP + H+ + L-glutamine + phosphate 0.24773229701431493 +r_0476 glutamine synthetase 0.029297138047138047 prot_P32288 + ammonium + ATP + L-glutamate --> ADP + H+ + L-glutamine + phosphate 0.2716245224107091 r_0477 glutamine-fructose-6-phosphate transaminase 0.6263458528951487 prot_P14742 + D-fructose 6-phosphate + L-glutamine --> alpha-D-glucosamine 6-phosphate + L-glutamate 0.0023610000000000003 r_0478 glutaminyl-tRNA synthetase 15.369603878657363 prot_P13188 + ATP + L-glutamine + tRNA(Gln) --> AMP + diphosphate + Gln-tRNA(Gln) 0.0141160332291015 r_0479 glutamyl-tRNA synthetase 4.974688861932783 prot_P46655 + ATP + L-glutamate + tRNA(Glu) --> AMP + diphosphate + Glu-tRNA(Glu) 0.029648731201628798 r_0480 glutamyl-tRNA synthetase 11.407962962962962 prot_P48525 + ATP + L-glutamate + tRNA(Glu) --> AMP + diphosphate + Glu-tRNA(Glu) 0.0 -r_0481_EXP_1 glutathione oxidoreductase 0.0038209876543209877 prot_P25373 + 0.016494135802469136 prot_P41921 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0044528510230289154 +r_0481_EXP_1 glutathione oxidoreductase 0.0038209876543209877 prot_P25373 + 0.016494135802469136 prot_P41921 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0 r_0481_EXP_2 glutathione oxidoreductase 0.016494135802469136 prot_P41921 + 0.00872253086419753 prot_Q03835 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0 r_0481_EXP_3 glutathione oxidoreductase 0.00489537037037037 prot_P17695 + 0.016494135802469136 prot_P41921 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0 r_0481_EXP_4 glutathione oxidoreductase 0.008485493827160493 prot_P32642 + 0.016494135802469136 prot_P41921 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0 r_0482 glutathione oxidoreductase 0.016494135802469136 prot_P41921 + 0.0052256172839506175 prot_Q02784 + glutathione disulfide + H+ + NADPH --> 2.0 glutathione + NADP(+) 0.0 r_0483_EXP_1 glutathione peridoxase 0.009786866919412851 prot_P23202 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0483_EXP_2 glutathione peridoxase 0.269093567251462 prot_P38143 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 -r_0483_EXP_3 glutathione peridoxase 0.0030086516963157383 prot_P25373 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0044528510230289154 +r_0483_EXP_3 glutathione peridoxase 0.0030086516963157383 prot_P25373 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0483_EXP_4 glutathione peridoxase 0.0038546223388743073 prot_P17695 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0483_EXP_5 glutathione peridoxase 0.2725292397660819 prot_P40581 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0483_EXP_6 glutathione peridoxase 0.3697285294019552 prot_P36014 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 r_0484 glutathione peroxidase, mitochondria 1.0350179133060056 prot_Q02784 + 2.0 glutathione + hydrogen peroxide --> glutathione disulfide + 2.0 H2O 0.0 -r_0485 glutathione synthetase 0.2818939393939394 prot_Q08220 + ATP + L-gamma-glutamyl-L-cysteine + L-glycine --> ADP + glutathione + H+ + phosphate 9.999999999940612e-08 +r_0485 glutathione synthetase 0.2818939393939394 prot_Q08220 + ATP + L-gamma-glutamyl-L-cysteine + L-glycine --> ADP + glutathione + H+ + phosphate 1e-07 r_0486_EXP_1 glyceraldehyde-3-phosphate dehydrogenase 1.091178266178266 prot_P00359 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 0.0 r_0486_EXP_2 glyceraldehyde-3-phosphate dehydrogenase 0.1416581138487952 prot_P00360 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 2.173281483261699 -r_0486_EXP_3 glyceraldehyde-3-phosphate dehydrogenase 0.5962574850299401 prot_P00358 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 4.0315610011388445 +r_0486_EXP_3 glyceraldehyde-3-phosphate dehydrogenase 0.5962574850299401 prot_P00358 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 4.0652699156302745 r_0486_REV_EXP_1 glyceraldehyde-3-phosphate dehydrogenase (reversible) 1.091178266178266 prot_P00359 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 r_0486_REV_EXP_2 glyceraldehyde-3-phosphate dehydrogenase (reversible) 0.3424329501915709 prot_P00360 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 r_0486_REV_EXP_3 glyceraldehyde-3-phosphate dehydrogenase (reversible) 0.5962574850299401 prot_P00358 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 @@ -609,19 +609,19 @@ r_0488 glycerol kinase 0.013277445109780439 prot_P32190 + ATP + glycerol --> ADP r_0489_EXP_1 glycerol-3-phosphatase 0.6923038630027878 prot_P40106 + glycerol 3-phosphate + H2O --> glycerol + phosphate 0.11203825872 r_0489_EXP_2 glycerol-3-phosphatase 0.6956142970927918 prot_P41277 + glycerol 3-phosphate + H2O --> glycerol + phosphate 0.0 r_0490 glycerol-3-phosphate dehydrogenase (fad) 0.6038455121788456 prot_P32191 + FAD + glycerol 3-phosphate + H+ --> dihydroxyacetone phosphate + FADH2 0.0 -r_0491_EXP_1 glycerol-3-phosphate dehydrogenase (NAD) 0.10538102261553589 prot_Q00055 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.11899319148426349 +r_0491_EXP_1 glycerol-3-phosphate dehydrogenase (NAD) 0.10538102261553589 prot_Q00055 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.11899319148423666 r_0491_EXP_2 glycerol-3-phosphate dehydrogenase (NAD) 0.1214896755162242 prot_P41911 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.0 r_0492 glycerol-3-phosphate dehydrogenase (NAD) 0.1214896755162242 prot_P41911 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.0 r_0497 glycerophosphodiester phosphodiesterase (glycerophosphocholine) 0.174260101010101 prot_Q02979 + H2O + sn-glycero-3-phosphocholine --> choline + glycerol 3-phosphate + H+ 0.0 -r_0499 glycinamide ribotide transformylase 0.1634722222222222 prot_P04161 + 10-formyl-THF + 5-phospho-ribosyl-glycineamide --> 5'-phosphoribosyl-N-formylglycineamide + H+ + THF 0.010240426385252575 +r_0499 glycinamide ribotide transformylase 0.1634722222222222 prot_P04161 + 10-formyl-THF + 5-phospho-ribosyl-glycineamide --> 5'-phosphoribosyl-N-formylglycineamide + H+ + THF 0.010240426385254225 r_0500 glycine C-acetyltransferase 0.062476381011109826 prot_standard + coenzyme A + L-2-amino-3-oxobutanoate --> acetyl-CoA + L-glycine 0.0 r_0501 glycine cleavage system 0.17131712790948955 prot_P09624 + 0.05961049407152449 prot_P39726 + 0.14105353380868527 prot_P48015 + 0.3630330791773559 prot_P49095 + L-glycine + NAD + THF --> 5,10-methylenetetrahydrofolate + ammonium + carbon dioxide + NADH 0.0 -r_0502 glycine hydroxymethyltransferase 0.0226640625 prot_P37291 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 0.48683135550290574 +r_0502 glycine hydroxymethyltransferase 0.0226640625 prot_P37291 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 0.4868682329351178 r_0502_REV glycine hydroxymethyltransferase (reversible) 63.06521739130435 prot_P37291 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF 0.0 -r_0503 glycine hydroxymethyltransferase 0.023301215277777777 prot_P37292 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 1.8993174939014002e-05 -r_0503_REV glycine hydroxymethyltransferase (reversible) 64.83816425120773 prot_P37292 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF -6.8256722437081565e-09 +r_0503 glycine hydroxymethyltransferase 0.023301215277777777 prot_P37292 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 1.899317493904273e-05 +r_0503_REV glycine hydroxymethyltransferase (reversible) 64.83816425120773 prot_P37292 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF -6.8256722437184805e-09 r_0504 glycine-cleavage complex (lipoamide) 0.023116760828625234 prot_P09624 + 0.00804357130628317 prot_P39726 + 0.019033127889060093 prot_P48015 + 0.048986046909775725 prot_P49095 + H+ + L-glycine + lipoamide --> carbon dioxide + S(8)-aminomethyldihydrolipoamide 0.0 -r_0505_EXP_1 glycine-cleavage complex (lipoamide) 0.016688295637127672 prot_P09624 + 0.005806760598195526 prot_P39726 + 0.013740266963292547 prot_P48015 + 0.0353636756890372 prot_P49095 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 1.483945717424315 +r_0505_EXP_1 glycine-cleavage complex (lipoamide) 0.016688295637127672 prot_P09624 + 0.005806760598195526 prot_P39726 + 0.013740266963292547 prot_P48015 + 0.0353636756890372 prot_P49095 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 1.518442820796261 r_0505_EXP_2 glycine-cleavage complex (lipoamide) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 0.0 r_0506 glycine-cleavage complex (lipoylprotein) 0.04357695209331861 prot_P09624 + 0.015162778387145652 prot_P39726 + 0.0358789757940712 prot_P48015 + 0.09234263551254228 prot_P49095 + L-glycine + lipoylprotein --> carbon dioxide + S(8)-aminomethyldihydrolipoylprotein 0.0 r_0507 glycine-cleavage complex (lipoylprotein) 0.2838103427329358 prot_P09624 + 0.0987529674315879 prot_P39726 + 0.23367454417683617 prot_P48015 + 0.6014141369399599 prot_P49095 + H+ + S(8)-aminomethyldihydrolipoylprotein + THF --> 5,10-methylenetetrahydrofolate + ammonium + dihydrolipoylprotein 0.0 @@ -634,7 +634,7 @@ r_0510_EXP_4 glycogen (starch) synthase 18.96007470955954 prot_P27472 + 16.50835 r_0511 glycogen phosphorylase 0.568069306930693 prot_P06738 + glycogen + phosphate --> D-glucose 1-phosphate 0.0 r_0512_EXP_1 glycyl-tRNA synthetase 29.750380517503807 prot_P38088 + ATP + L-glycine + tRNA(Gly) --> AMP + diphosphate + Gly-tRNA(Gly) 0.0 r_0512_EXP_2 glycyl-tRNA synthetase 1.2407058001397624 prot_Q06817 + ATP + L-glycine + tRNA(Gly) --> AMP + diphosphate + Gly-tRNA(Gly) 0.0283748983111195 -r_0514 GMP synthase 0.0098038624019312 prot_P38625 + ATP + H2O + L-glutamine + xanthosine-5-phosphate --> AMP + diphosphate + GMP + 2.0 H+ + L-glutamate 0.004799823201108153 +r_0514 GMP synthase 0.0098038624019312 prot_P38625 + ATP + H2O + L-glutamine + xanthosine-5-phosphate --> AMP + diphosphate + GMP + 2.0 H+ + L-glutamate 0.004799823201108236 r_0518 GPI-anchor assembly, step 2 149.73523909383033 prot_P23797 + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O --> 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate + H+ 0.0 r_0518_REV GPI-anchor assembly, step 2 (reversible) 60.09087553078704 prot_P23797 + 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate + H+ --> 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O 0.0 r_0519 GPI-anchor assembly, step 5 1.0741619906421145 prot_P25580 + 1.0571943419782979 prot_P47088 + 6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol + dolichyl D-mannosyl phosphate --> 6-O-[alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + dolichyl phosphate 0.0 @@ -649,11 +649,11 @@ r_0523_EXP_1 GPI-anchor assembly, step 9 0.007109647641562535 prot_Q06636 + 6-O- r_0523_EXP_2 GPI-anchor assembly, step 9 0.03254362265000563 prot_Q07830 + 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone --> 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone 0.0 r_0523_REV_EXP_1 GPI-anchor assembly, step 9 (reversible) 0.007109647641562535 prot_Q06636 + 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone --> 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone 0.0 r_0523_REV_EXP_2 GPI-anchor assembly, step 9 (reversible) 0.03254362265000563 prot_Q07830 + 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone --> 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone 0.0 -r_0524 GTP cyclohydrolase I 197.7849002849003 prot_P51601 + GTP + H2O --> 7,8-dihydroneopterin 3'-triphosphate + formate + H+ 6.340000254510467e-06 +r_0524 GTP cyclohydrolase I 197.7849002849003 prot_P51601 + GTP + H2O --> 7,8-dihydroneopterin 3'-triphosphate + formate + H+ 6.340000254623224e-06 r_0525 GTP cyclohydrolase II 0.024647633744855967 prot_P38066 + GTP + 3.0 H2O --> 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + diphosphate + formate + 2.0 H+ 9.999999710998968e-05 r_0526 guanine deaminase 1.7229712858926343 prot_Q07729 + guanine + H+ + H2O --> 9H-xanthine + ammonium 0.0 r_0527 guanine phosphoribosyltransferase 0.09123207301173403 prot_Q04178 + guanine + PRPP --> diphosphate + GMP 0.0 -r_0528 guanylate kinase 0.014549492385786802 prot_P15454 + ATP + GMP --> ADP + GDP 0.000346340008763912 +r_0528 guanylate kinase 0.014549492385786802 prot_P15454 + ATP + GMP --> ADP + GDP 0.0003463400087639953 r_0529 guanylate kinase (GMP:dATP) 0.014549492385786802 prot_P15454 + dATP + GMP --> dADP + GDP 0.0 r_0529_REV guanylate kinase (GMP:dATP) (reversible) 0.014549492385786802 prot_P15454 + dADP + GDP --> dATP + GMP 0.0 r_0530_EXP_1 heme O monooxygenase 0.5821949882086304 prot_P40086 + heme o + NADH + oxygen --> H2O + heme a + NAD 0.0 @@ -686,40 +686,40 @@ r_0543_EXP_2 homocitrate synthase 21.204303979830723 prot_P48570 + 2-oxoglutarat r_0544_EXP_1 homocysteine S-methyltransferase 26.83845029239766 prot_Q12525 + L-homocysteine + S-adenosyl-L-methionine --> H+ + L-methionine + S-adenosyl-L-homocysteine 0.0 r_0544_EXP_2 homocysteine S-methyltransferase 26.80482456140351 prot_Q08985 + L-homocysteine + S-adenosyl-L-methionine --> H+ + L-methionine + S-adenosyl-L-homocysteine 0.0 r_0545 homoisocitrate dehydrogenase 0.6547222222222222 prot_P40495 + homoisocitrate + NAD --> 2-oxoadipic acid + carbon dioxide + NADH 0.032939964005654 -r_0546 homoserine dehydrogenase (NADH) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADH --> L-homoserine + NAD 0.0354420994434098 +r_0546 homoserine dehydrogenase (NADH) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADH --> L-homoserine + NAD 0.03544209944340982 r_0547 homoserine dehydrogenase (NADP) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADPH --> L-homoserine + NADP(+) 0.0 r_0548 homoserine kinase 0.263562091503268 prot_P17423 + ATP + L-homoserine --> ADP + H+ + O-phospho-L-homoserine 0.023517302829840103 -r_0549 homoserine O-trans-acetylase 0.9806103801169591 prot_P08465 + acetyl-CoA + L-homoserine --> coenzyme A + O-acetyl-L-homoserine 0.011924796613569698 +r_0549 homoserine O-trans-acetylase 0.9806103801169591 prot_P08465 + acetyl-CoA + L-homoserine --> coenzyme A + O-acetyl-L-homoserine 0.011924796613569717 r_0550_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.3160087719298246 prot_Q04120 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0550_EXP_2 hydrogen peroxide reductase (thioredoxin) 0.1642543859649123 prot_P22217 + 0.3160087719298246 prot_Q04120 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0551 hydrogen peroxide reductase (thioredoxin) 0.07592592592592592 prot_P25372 + 0.15517676767676766 prot_P34227 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 -r_0552_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.2794590643274854 prot_P38013 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.006721699195495709 +r_0552_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.2794590643274854 prot_P38013 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0552_EXP_2 hydrogen peroxide reductase (thioredoxin) 0.1642543859649123 prot_P22217 + 0.2794590643274854 prot_P38013 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 -r_0553 hydroxyacylglutathione hydrolase 0.008888605152650096 prot_Q05584 + (R)-S-lactoylglutathione + H2O --> (R)-lactate + glutathione + H+ 0.0 +r_0553 hydroxyacylglutathione hydrolase 0.008888605152650096 prot_Q05584 + (R)-S-lactoylglutathione + H2O --> (R)-lactate + glutathione + H+ 0.04350234197142867 r_0554 hydroxyacylglutathione hydrolase 0.009175746226308025 prot_Q12320 + (R)-S-lactoylglutathione + H2O --> (R)-lactate + glutathione + H+ 0.0 r_0555 hydroxybenzoate octaprenyltransferase 0.8535401716463751 prot_P32378 + 4-hydroxybenzoate + hexaprenyl diphosphate --> 3-hexaprenyl-4-hydroxybenzoic acid + diphosphate 0.0 r_0556 hydroxyethylthiazole kinase 12.64725296618268 prot_P41835 + 5-(2-hydroxyethyl)-4-methylthiazole + ATP --> 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ 0.0 r_0557 hydroxymethylbilane synthase 163.0 prot_P28789 + H2O + 4.0 porphobilinogen --> 4.0 ammonium + preuroporphyrinogen 0.0 r_0558_EXP_1 hydroxymethylglutaryl CoA reductase 1.5450320512820512 prot_P12684 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.0 -r_0558_EXP_2 hydroxymethylglutaryl CoA reductase 1.544150641025641 prot_P12683 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.02234772406386473 -r_0560 hydroxymethylglutaryl CoA synthase 3.322101449275362 prot_P54839 + acetoacetyl-CoA + acetyl-CoA + H2O --> 3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ 0.02234772406386473 +r_0558_EXP_2 hydroxymethylglutaryl CoA reductase 1.544150641025641 prot_P12683 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.022126459469172983 +r_0560 hydroxymethylglutaryl CoA synthase 3.322101449275362 prot_P54839 + acetoacetyl-CoA + acetyl-CoA + H2O --> 3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ 0.022126459469172983 r_0561_EXP_1 hydroxymethylpyrimidine kinase (ATP) 39.57945736434109 prot_Q08224 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 1.20000004244503e-07 r_0561_EXP_2 hydroxymethylpyrimidine kinase (ATP) 39.62144702842377 prot_Q08975 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 r_0561_EXP_3 hydroxymethylpyrimidine kinase (ATP) 340.09581877502734 prot_Q06490 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 r_0562 hypoxanthine phosphoribosyltransferase (Hypoxanthine) 0.30556768558951963 prot_Q04178 + hypoxanthine + PRPP --> diphosphate + IMP 0.0 r_0563 Imidazole-glycerol-3-phosphate synthase 2.4584541062801932 prot_P33734 + 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + L-glutamine --> AICAR + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H+ + L-glutamate 0.008356708763266002 r_0564 imidazoleglycerol-phosphate dehydratase 0.004728769841269841 prot_P06633 + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate --> 3-(imidazol-4-yl)-2-oxopropyl dihydrogen phosphate + H2O 0.008356708763266002 -r_0565_EXP_1 IMP dehydrogenase 6.383242999096658 prot_P38697 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.004517258358922197 +r_0565_EXP_1 IMP dehydrogenase 6.383242999096658 prot_P38697 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0045172583589222805 r_0565_EXP_2 IMP dehydrogenase 6.389453477868112 prot_P50095 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0 r_0565_EXP_3 IMP dehydrogenase 6.367886178861789 prot_P50094 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0002825648421859555 -r_0566 indole-3-glycerol-phosphate synthase 1.550264949662187 prot_P00937 + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ --> 1-C-(indol-3-yl)glycerol 3-phosphate + carbon dioxide + H2O 0.004508621257677621 +r_0566 indole-3-glycerol-phosphate synthase 1.550264949662187 prot_P00937 + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ --> 1-C-(indol-3-yl)glycerol 3-phosphate + carbon dioxide + H2O 0.004508621257685833 r_0567_EXP_1 indole-3-pyruvate decarboxylase 0.27589605734767025 prot_P26263 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 r_0567_EXP_2 indole-3-pyruvate decarboxylase 0.11780651340996169 prot_P06169 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 r_0567_EXP_3 indole-3-pyruvate decarboxylase 0.27738351254480287 prot_P16467 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 -r_0568 inorganic diphosphatase 0.03450854700854701 prot_P00817 + diphosphate + H2O --> H+ + 2.0 phosphate 1.3637741291616305 -r_0569 inorganic diphosphatase 0.03800534188034188 prot_P28239 + diphosphate + H2O --> H+ + 2.0 phosphate 0.0 +r_0568 inorganic diphosphatase 0.03450854700854701 prot_P00817 + diphosphate + H2O --> H+ + 2.0 phosphate 1.3841174918369008 +r_0569 inorganic diphosphatase 0.03800534188034188 prot_P28239 + diphosphate + H2O --> H+ + 2.0 phosphate 0.07047984546976684 r_0570_EXP_1 inosine monophosphate cyclohydrolase 2.10859173126615 prot_P54113 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.0 -r_0570_EXP_2 inosine monophosphate cyclohydrolase 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.018597015148514334 +r_0570_EXP_2 inosine monophosphate cyclohydrolase 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.018597015148515982 r_0570_REV_EXP_1 inosine monophosphate cyclohydrolase (reversible) 2.10859173126615 prot_P54113 + H2O + IMP --> phosphoribosyl-formamido-carboxamide 0.0 r_0570_REV_EXP_2 inosine monophosphate cyclohydrolase (reversible) 2.1079780361757106 prot_P38009 + H2O + IMP --> phosphoribosyl-formamido-carboxamide 0.0 r_0571 inositol-1,3,4,5,6-pentakisphosphate 2-kinase 12.457614290039357 prot_Q06667 + ATP + myo-inositol 1,3,4,5,6-pentakisphosphate --> ADP + H+ + myo-inositol hexakisphosphate 0.0 @@ -741,11 +741,11 @@ r_0606 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phos r_0607 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide A (C26) --> ceramide-1 (C26) + mannose-(1D-myo-inositol 1-phosphate)2 0.0 r_0608 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide B' (C24) --> ceramide-2' (C24) + mannose-(1D-myo-inositol 1-phosphate)2 0.0 r_0609 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide B' (C26) --> ceramide-2' (C26) + mannose-(1D-myo-inositol 1-phosphate)2 0.0 -r_0610 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide B (C24) --> ceramide-2 (C24) + mannose-(1D-myo-inositol 1-phosphate)2 0.0 +r_0610 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide B (C24) --> ceramide-2 (C24) + mannose-(1D-myo-inositol 1-phosphate)2 3.0481692437735226e-13 r_0611 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide B (C26) --> ceramide-2 (C26) + mannose-(1D-myo-inositol 1-phosphate)2 0.0 r_0612 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide C (C24) --> ceramide-3 (C24) + mannose-(1D-myo-inositol 1-phosphate)2 0.0 r_0613 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide C (C26) --> ceramide-3 (C26) + mannose-(1D-myo-inositol 1-phosphate)2 0.0 -r_0614 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide D (C24) --> ceramide-4 (C24) + mannose-(1D-myo-inositol 1-phosphate)2 0.0 +r_0614 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide D (C24) --> ceramide-4 (C24) + mannose-(1D-myo-inositol 1-phosphate)2 -3.0481692437735226e-13 r_0615 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol phosphomannosylinositol phosphoceramide D (C26) --> ceramide-4 (C26) + mannose-(1D-myo-inositol 1-phosphate)2 0.0 r_0616 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol-P-ceramide A (C24) --> 1D-myo-inositol 3-phosphate + ceramide-1 (C24) + 2.0 H+ 0.0 r_0617 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol-P-ceramide A (C26) --> 1D-myo-inositol 3-phosphate + ceramide-1 (C26) + 2.0 H+ 0.0 @@ -789,24 +789,24 @@ r_0654 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol-P-ce r_0655 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol-P-ceramide D (C26) --> 1D-myo-inositol 1-phosphate + ceramide-4 (C26) + 2.0 H+ 0.0 r_0656 isoamyl acetate-hydrolyzing esterase 6.693496157764181 prot_P41734 + H2O + isoamyl acetate --> acetate + H+ + isoamylol 0.0 r_0657 isobutyl acetate-hydrolyzing esterase 9.93658635305908 prot_P41734 + H2O + isobutyl acetate --> acetate + H+ + isobutanol 0.0 -r_0658 isocitrate dehydrogenase (NAD+) 0.5194640522875817 prot_P28241 + 0.5140392156862745 prot_P28834 + isocitrate + NAD --> 2-oxoglutarate + carbon dioxide + NADH 0.0 -r_0659 isocitrate dehydrogenase (NADP) 0.05072113289760349 prot_P41939 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 1.6209174817377987 +r_0658 isocitrate dehydrogenase (NAD+) 0.5194640522875817 prot_P28241 + 0.5140392156862745 prot_P28834 + isocitrate + NAD --> 2-oxoglutarate + carbon dioxide + NADH 0.6562259570714342 +r_0659 isocitrate dehydrogenase (NADP) 0.05072113289760349 prot_P41939 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.8012631159365224 r_0659_REV isocitrate dehydrogenase (NADP) (reversible) 2.6395691609977323 prot_P41939 + 2-oxoglutarate + carbon dioxide + NADPH --> isocitrate + NADP(+) 0.0 -r_0661 isocitrate dehydrogenase (NADP+), peroxisomal 0.05213071895424837 prot_P53982 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.0 -r_0662 isocitrate lyase 1.3133207070707071 prot_P28240 + isocitrate --> glyoxylate + succinate 0.024145054320875627 +r_0661 isocitrate dehydrogenase (NADP+), peroxisomal 0.05213071895424837 prot_P53982 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.00016913831181727956 +r_0662 isocitrate lyase 1.3133207070707071 prot_P28240 + isocitrate --> glyoxylate + succinate 0.024145054320906408 r_0663 isoleucine transaminase 0.010755813953488373 prot_P47176 + 2-oxoglutarate + L-isoleucine --> (S)-3-methyl-2-oxopentanoate + L-glutamate 0.0 r_0663_REV isoleucine transaminase (reversible) 0.010755813953488373 prot_P47176 + (S)-3-methyl-2-oxopentanoate + L-glutamate --> 2-oxoglutarate + L-isoleucine 0.0265490320174191 r_0664 isoleucine transaminase 0.011265116279069768 prot_P38891 + 2-oxoglutarate + L-isoleucine --> (S)-3-methyl-2-oxopentanoate + L-glutamate 0.0 r_0664_REV isoleucine transaminase (reversible) 0.011265116279069768 prot_P38891 + (S)-3-methyl-2-oxopentanoate + L-glutamate --> 2-oxoglutarate + L-isoleucine 0.0 r_0665 isoleucyl-tRNA synthetase 0.4249032614704257 prot_P09436 + ATP + L-isoleucine + tRNA(Ile) --> AMP + diphosphate + Ile-tRNA(Ile) 0.0265490320174191 r_0666 isoleucyl-tRNA synthetase 0.40006218905472635 prot_P48526 + ATP + L-isoleucine + tRNA(Ile) --> AMP + diphosphate + Ile-tRNA(Ile) 0.0 -r_0667 isopentenyl-diphosphate D-isomerase 1.1202472121456402 prot_P15496 + isopentenyl diphosphate --> prenyl diphosphate(3-) 0.007449241354621576 +r_0667 isopentenyl-diphosphate D-isomerase 1.1202472121456402 prot_P15496 + isopentenyl diphosphate --> prenyl diphosphate(3-) 0.007375486489724328 r_0667_REV isopentenyl-diphosphate D-isomerase (reversible) 1.1202472121456402 prot_P15496 + prenyl diphosphate(3-) --> isopentenyl diphosphate 0.0 r_0668 itaconate-CoA ligase (ADP-forming) 0.22156557067271354 prot_P53312 + 0.16549508692365836 prot_P53598 + ATP + coenzyme A + itaconate --> ADP + itaconyl-CoA + phosphate 0.0 r_0668_REV itaconate-CoA ligase (ADP-forming) (reversible) 0.5921843434343435 prot_P53312 + 0.44232323232323234 prot_P53598 + ADP + itaconyl-CoA + phosphate --> ATP + coenzyme A + itaconate 0.0 r_0669 ketol-acid reductoisomerase (2-aceto-2-hydroxybutanoate) 0.6734669095324833 prot_P06168 + (S)-2-acetyl-2-hydroxybutanoate + H+ + NADPH --> (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) 0.0265490320174191 -r_0670 kynureninase 1.2721196709441296 prot_Q05979 + H2O + L-kynurenine --> anthranilate + H+ + L-alanine 4.451981443090512e-05 -r_0671 kynurenine 3-monooxygenase 7.174192665571977 prot_P38169 + H+ + L-kynurenine + NADPH + oxygen --> 3-hydroxy-L-kynurenine + H2O + NADP(+) 0.0006071199974008957 +r_0670 kynureninase 1.2721196709441296 prot_Q05979 + H2O + L-kynurenine --> anthranilate + H+ + L-alanine 4.4639814446527544e-05 +r_0671 kynurenine 3-monooxygenase 7.174192665571977 prot_P38169 + H+ + L-kynurenine + NADPH + oxygen --> 3-hydroxy-L-kynurenine + H2O + NADP(+) 0.0006069999973934842 r_0672 L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase 11.932407407407407 prot_P07275 + 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H2O + NAD --> erythro-4-hydroxy-L-glutamic acid + H+ + NADH 0.0 r_0672_REV L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase (reversible) 11.932407407407407 prot_P07275 + erythro-4-hydroxy-L-glutamic acid + H+ + NADH --> 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H2O + NAD 0.0 r_0673 L-4-hydroxyglutamate semialdehyde dehydrogenase 11.932407407407407 prot_P07275 + H2O + L-4-hydroxyglutamic semialdehyde + NAD --> erythro-4-hydroxy-L-glutamic acid + 2.0 H+ + NADH 0.0 @@ -826,18 +826,18 @@ r_0681 L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase 0.0397325741 r_0682 L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase 0.04468167701863354 prot_Q01802 + 2-oxoglutarate + erythro-4-hydroxy-L-glutamic acid --> 4-hydroxy-2-oxoglutarate + L-glutamate 0.0 r_0683 L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase 0.039732574189095926 prot_P23542 + 2-oxoglutarate + erythro-4-hydroxy-L-glutamic acid --> 4-hydroxy-2-oxoglutarate + L-glutamate 0.0 r_0687 L-hydroxyproline reductase (NADP) 0.0020925 prot_P32263 + 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H+ + NADPH --> NADP(+) + trans-4-hydroxy-L-proline 0.0 -r_0688_EXP_1 L-lactaldehyde:NADP+ 1-oxidoreductase 60.65196078431372 prot_P38715 + H+ + methylglyoxal + NADPH --> (S)-lactaldehyde + NADP(+) 0.0017244997514388179 -r_0688_EXP_2 L-lactaldehyde:NADP+ 1-oxidoreductase 2.8890402664244625 prot_Q12068 + H+ + methylglyoxal + NADPH --> (S)-lactaldehyde + NADP(+) 0.018630538012133237 +r_0688_EXP_1 L-lactaldehyde:NADP+ 1-oxidoreductase 60.65196078431372 prot_P38715 + H+ + methylglyoxal + NADPH --> (S)-lactaldehyde + NADP(+) 0.0 +r_0688_EXP_2 L-lactaldehyde:NADP+ 1-oxidoreductase 2.8890402664244625 prot_Q12068 + H+ + methylglyoxal + NADPH --> (S)-lactaldehyde + NADP(+) 0.0 r_0689 L-serine deaminase 0.018661443494776827 prot_P25379 + L-serine --> ammonium + pyruvate 0.0 r_0690 L-serine dehydrogenase 0.7363131313131314 prot_Q05016 + L-serine + NADP(+) --> H+ + L-alpha-formylglycine + NADPH 0.0 r_0691 L-sorbitol dehydrogenase (L-sorbose-producing) 0.7983182730923695 prot_P35497 + L-glucitol + NAD --> H+ + L-sorbose + NADH 0.0 r_0692 L-threonine deaminase 0.007720611346848971 prot_P25379 + L-threonine --> 2-oxobutanoate + ammonium 0.0 r_0693 L-threonine deaminase 0.01253948609146629 prot_P00927 + L-threonine --> 2-oxobutanoate + ammonium 0.0 -r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.3527200202735511 prot_P47125 + L-tryptophan + oxygen --> N-formyl-L-kynurenine 0.0006516398118318009 +r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.3527200202735511 prot_P47125 + L-tryptophan + oxygen --> N-formyl-L-kynurenine 0.0006516398118400122 r_0695 L-tyrosine N-formyltransferase 52.20067092135934 prot_P21623 + 10-formyl-THF + L-tyrosine --> H+ + N-formyl-L-tyrosine + THF 0.0 -r_0696 lactaldehyde dehydrogenase 0.033859544541667556 prot_Q12068 + (S)-lactaldehyde + H2O + NAD --> (S)-lactate + 2.0 H+ + NADH 0.020355037763572052 -r_0697 lactoylglutathione lyase 0.005679029304029304 prot_P50107 + glutathione + methylglyoxal --> (R)-S-lactoylglutathione 0.0 -r_0698 lanosterol synthase 24.44598824754819 prot_P38604 + (S)-2,3-epoxysqualene --> lanosterol 0.0037246206773107857 +r_0696 lactaldehyde dehydrogenase 0.033859544541667556 prot_Q12068 + (S)-lactaldehyde + H2O + NAD --> (S)-lactate + 2.0 H+ + NADH 0.0 +r_0697 lactoylglutathione lyase 0.005679029304029304 prot_P50107 + glutathione + methylglyoxal --> (R)-S-lactoylglutathione 0.04350234197142867 +r_0698 lanosterol synthase 24.44598824754819 prot_P38604 + (S)-2,3-epoxysqualene --> lanosterol 0.003687743244862164 r_0699 leucine transaminase 0.012875835189309577 prot_P47176 + 2-oxoglutarate + L-leucine --> 4-methyl-2-oxopentanoate + L-glutamate 0.0 r_0699_REV leucine transaminase (reversible) 0.010755813953488373 prot_P47176 + 4-methyl-2-oxopentanoate + L-glutamate --> 2-oxoglutarate + L-leucine 0.0362523293945085 r_0700 leucine transaminase 0.013485523385300667 prot_P38891 + 2-oxoglutarate + L-leucine --> 4-methyl-2-oxopentanoate + L-glutamate 0.0 @@ -858,16 +858,16 @@ r_0708 leukotriene A4 hydrolase 1.0690022111663904 prot_Q10740 + H2O + leukotrie r_0708_REV leukotriene A4 hydrolase (reversible) 4.1321047008547005 prot_Q10740 + leukotriene B4 --> H2O + leukotriene A4 0.0 r_0711 lysyl-tRNA synthetase 0.41307439824945297 prot_P15180 + ATP + L-lysine + tRNA(Lys) --> AMP + diphosphate + Lys-tRNA(Lys) 0.032939964005654 r_0712 lysyl-tRNA synthetase 0.40194505227327987 prot_P32048 + ATP + L-lysine + tRNA(Lys) --> AMP + diphosphate + Lys-tRNA(Lys) 0.0 -r_0713 malate dehydrogenase 0.05201038748832867 prot_P17505 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 1.6451374144245416 +r_0713 malate dehydrogenase 0.05201038748832867 prot_P17505 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 1.6798707769237793 r_0713_REV malate dehydrogenase (reversible) 0.05201038748832867 prot_P17505 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.0 r_0714 malate dehydrogenase, cytoplasmic 0.009916009348524686 prot_P22133 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.0 -r_0714_REV malate dehydrogenase, cytoplasmic (reversible) 9.304413377192983e-05 prot_P22133 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.24932195098185356 +r_0714_REV malate dehydrogenase, cytoplasmic (reversible) 9.304413377192983e-05 prot_P22133 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.32413538038227646 r_0715 malate dehydrogenase, peroxisomal 0.009052974973220372 prot_P32419 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.0 -r_0715_REV malate dehydrogenase, peroxisomal (reversible) 8.494608918128655e-05 prot_P32419 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.007291543768627552 +r_0715_REV malate dehydrogenase, peroxisomal (reversible) 8.494608918128655e-05 prot_P32419 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.001183968182720957 r_0716_EXP_1 malate synthase 0.9084780092592593 prot_P21826 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 -r_0716_EXP_2 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.024219932686743 +r_0716_EXP_2 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.024229208231651925 r_0717 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 -r_0718 malic enzyme (NAD) 0.15417910447761193 prot_P36013 + (S)-malate + NAD --> carbon dioxide + NADH + pyruvate 0.22997082600054933 +r_0718 malic enzyme (NAD) 0.15417910447761193 prot_P36013 + (S)-malate + NAD --> carbon dioxide + NADH + pyruvate 0.2560346357906393 r_0719 malic enzyme (NADP) 0.15417910447761193 prot_P36013 + (S)-malate + NADP(+) --> carbon dioxide + NADPH + pyruvate 0.0 r_0721 malonyl-CoA-ACP transacylase 0.0018443121693121694 prot_P32463 + 0.0053845238095238095 prot_Q12283 + H+ + malonyl-CoA + ACP1 --> carboxyacetyl-ACP + coenzyme A 0.0 r_0721_REV malonyl-CoA-ACP transacylase (reversible) 0.0018443121693121694 prot_P32463 + 0.0053845238095238095 prot_Q12283 + carboxyacetyl-ACP + coenzyme A --> H+ + malonyl-CoA + ACP1 0.0 @@ -876,23 +876,23 @@ r_0723 mannose-6-phosphate isomerase 0.6692916666666666 prot_P29952 + D-mannose r_0723_REV mannose-6-phosphate isomerase (reversible) 0.09493498817966903 prot_P29952 + D-fructose 6-phosphate --> D-mannose 6-phosphate 0.070204 r_0724 methenyltetrahydrifikate cyclohydrolase 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.0 r_0724_REV methenyltetrahydrifikate cyclohydrolase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O 0.0 -r_0725 methenyltetrahydrofolate cyclohydrolase 1.3619742369207077 prot_P07245 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.4642157630287095 +r_0725 methenyltetrahydrofolate cyclohydrolase 1.3619742369207077 prot_P07245 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.4642526404611531 r_0725_REV methenyltetrahydrofolate cyclohydrolase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O 0.0 -r_0726_EXP_1 methionine adenosyltransferase 1.565037037037037 prot_P19358 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.015335596857434765 +r_0726_EXP_1 methionine adenosyltransferase 1.565037037037037 prot_P19358 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.01533559685720487 r_0726_EXP_2 methionine adenosyltransferase 19.92471888698304 prot_P10659 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.0 -r_0727 methionine synthase 24.2238162581693 prot_P05694 + 5-methyltetrahydrofolate + L-homocysteine --> L-methionine + THF 0.02225559248037856 +r_0727 methionine synthase 24.2238162581693 prot_P05694 + 5-methyltetrahydrofolate + L-homocysteine --> L-methionine + THF 0.02225559248014866 r_0728 methionyl-tRNA formyltransferase 95.33547008547009 prot_P32785 + 10-formyl-THF + Met-tRNA(Met) --> fMet-tRNA(fMet) + H+ + THF 0.0 r_0729 methionyl-tRNA synthetase 0.9519777777777778 prot_P00958 + ATP + L-methionine + tRNA(Met) --> AMP + diphosphate + Met-tRNA(Met) 0.00814974664727417 r_0730 methionyl-tRNA synthetase 0.7414888888888889 prot_P22438 + ATP + L-methionine + tRNA(Met) --> AMP + diphosphate + Met-tRNA(Met) 0.0 -r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 3.4304661673761956 prot_Q02046 + 5,10-methylenetetrahydrofolate + NAD --> 5,10-methenyl-THF + NADH 0.4642157630287095 +r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 3.4304661673761956 prot_Q02046 + 5,10-methylenetetrahydrofolate + NAD --> 5,10-methenyl-THF + NADH 0.4642526404611531 r_0732 methylenetetrahydrofolate dehydrogenase (NADP) 3.1493641930417993 prot_P07245 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) 0.0 r_0733 methylenetetrahydrofolate dehydrogenase (NADP) 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) 0.0 -r_0734 methylisocitrate lyase 1.3673400673400673 prot_Q12031 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> pyruvate + succinate 7.487836586737207e-05 -r_0735 mevalonate kinase (atp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + ATP --> (R)-5-phosphomevalonic acid + ADP + H+ 0.02234772406386473 +r_0734 methylisocitrate lyase 1.3673400673400673 prot_Q12031 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> pyruvate + succinate 7.48783658978421e-05 +r_0735 mevalonate kinase (atp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + ATP --> (R)-5-phosphomevalonic acid + ADP + H+ 0.022126459469172983 r_0736 mevalonate kinase (ctp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + CTP --> (R)-5-phosphomevalonic acid + CDP + H+ 0.0 r_0737 mevalonate kinase (gtp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + GTP --> (R)-5-phosphomevalonic acid + GDP + H+ 0.0 r_0738 mevalonate kinase (UTP) 0.4723196881091618 prot_P07277 + (R)-mevalonate + UTP --> (R)-5-phosphomevalonic acid + H+ + UDP 0.0 -r_0739 mevalonate pyrophoshate decarboxylase 2.500907029478458 prot_P32377 + (R)-5-diphosphomevalonic acid + ATP --> ADP + carbon dioxide + isopentenyl diphosphate + phosphate 0.02234772406386473 +r_0739 mevalonate pyrophoshate decarboxylase 2.500907029478458 prot_P32377 + (R)-5-diphosphomevalonic acid + ATP --> ADP + carbon dioxide + isopentenyl diphosphate + phosphate 0.022126459469172983 r_0747_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide A (C24) --> GDP + H+ + mannosylinositol phosphorylceramide A (C24) 0.0 r_0747_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide A (C24) --> GDP + H+ + mannosylinositol phosphorylceramide A (C24) 0.0 r_0748_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide A (C26) --> GDP + H+ + mannosylinositol phosphorylceramide A (C26) 0.0 @@ -913,16 +913,16 @@ r_0755_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 pro r_0755_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide D (C24) --> GDP + H+ + mannosylinositol phosphorylceramide D (C24) 0.0 r_0756_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide D (C26) --> GDP + H+ + mannosylinositol phosphorylceramide D (C26) 0.0 r_0756_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide D (C26) --> GDP + H+ + mannosylinositol phosphorylceramide D (C26) 0.0 -r_0757_EXP_1 myo-inositol 1-phosphatase 0.03326388888888889 prot_Q05533 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0008256834141099491 +r_0757_EXP_1 myo-inositol 1-phosphatase 0.03326388888888889 prot_Q05533 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0008256834141111996 r_0757_EXP_2 myo-inositol 1-phosphatase 0.0340205223880597 prot_P38710 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0 -r_0758 myo-inositol-1-phosphate synthase 1.7257523148148148 prot_P11986 + D-glucose 6-phosphate --> 1D-myo-inositol 1-phosphate 0.0008256834141099491 +r_0758 myo-inositol-1-phosphate synthase 1.7257523148148148 prot_P11986 + D-glucose 6-phosphate --> 1D-myo-inositol 1-phosphate 0.0008256834141111996 r_0759 N-acetyl-g-glutamyl-phosphate reductase 3.4224025974025976 prot_Q01217 + H+ + N-acetyl-L-gamma-glutamyl phosphate + NADPH --> 2-acetamido-5-oxopentanoate + NADP(+) + phosphate 0.031792910688328326 r_0760 N-acetylglucosamine-6-phosphate synthase 0.4886032977691562 prot_P43577 + acetyl-CoA + alpha-D-glucosamine 6-phosphate --> coenzyme A + H+ + N-acetyl-D-glucosamine 6-phosphate 0.0023610000000000003 r_0761_EXP_1 N-acteylglutamate synthase 82.8409090909091 prot_P40360 + acetyl-CoA + L-glutamate --> coenzyme A + H+ + N-acetyl-L-glutamate 0.0 r_0761_EXP_2 N-acteylglutamate synthase 0.6359516214779373 prot_Q04728 + acetyl-CoA + L-glutamate --> coenzyme A + H+ + N-acetyl-L-glutamate 0.0 r_0761_REV_EXP_1 N-acteylglutamate synthase (reversible) 23.365384615384617 prot_P40360 + coenzyme A + H+ + N-acetyl-L-glutamate --> acetyl-CoA + L-glutamate 0.0 r_0761_REV_EXP_2 N-acteylglutamate synthase (reversible) 0.6359516214779373 prot_Q04728 + coenzyme A + H+ + N-acetyl-L-glutamate --> acetyl-CoA + L-glutamate 0.0 -r_0762 N-formyl-L-kynurenine amidohydrolase 0.05174430641821946 prot_Q04066 + H2O + N-formyl-L-kynurenine --> formate + H+ + L-kynurenine 0.0006516398118318009 +r_0762 N-formyl-L-kynurenine amidohydrolase 0.05174430641821946 prot_Q04066 + H2O + N-formyl-L-kynurenine --> formate + H+ + L-kynurenine 0.0006516398118400122 r_0763 N-formyltyrosine oxidase 70.69806925295306 prot_P21595 + 77.40588128458634 prot_P21623 + H+ + 2.0 N-formyl-L-tyrosine + NADPH --> N,N'-diformyldityrosine + NADP(+) 0.0 r_0764 NAD diphosphatase 4835.111111111111 prot_P53164 + H2O + NAD --> AMP + 2.0 H+ + NMN 0.0 r_0765_EXP_1 NAD kinase 18.47685185185185 prot_P32622 + ATP + NAD --> ADP + H+ + NADP(+) 0.0 @@ -935,18 +935,18 @@ r_0767_EXP_2 NAD nucleosidase nuclear 42.186868686868685 prot_P53688 + H2O + NAD r_0767_EXP_3 NAD nucleosidase nuclear 58.28484848484848 prot_P53685 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 r_0767_EXP_4 NAD nucleosidase nuclear 51.03434343434343 prot_P53687 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 r_0767_EXP_5 NAD nucleosidase nuclear 40.38282828282828 prot_P53686 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 -r_0768 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0006071199974008957 +r_0768 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0006071199973977287 r_0769 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0 r_0769_REV NAD synthase (reversible) 3.5019965277777776 prot_P38795 + AMP + diphosphate + H+ + L-glutamate + NAD --> ATP + deamido-NAD(+) + H2O + L-glutamine 0.0 -r_0770_EXP_1 NADH dehydrogenase, cytosolic/mitochondrial 0.034255 prot_Q07500 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 5.13511143803178 +r_0770_EXP_1 NADH dehydrogenase, cytosolic/mitochondrial 0.034255 prot_Q07500 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 5.27024724702105 r_0770_EXP_2 NADH dehydrogenase, cytosolic/mitochondrial 0.034874444444444444 prot_P40215 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 0.0 r_0771_EXP_1 NADH kinase 0.9640096618357487 prot_P32622 + ATP + NADH --> ADP + H+ + NADPH 0.0 -r_0771_EXP_2 NADH kinase 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.00032700000447238864 +r_0771_EXP_2 NADH kinase 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.00032700000442788604 r_0772_EXP_1 NADH kinase mitochondrial 0.9640096618357487 prot_P32622 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0772_EXP_2 NADH kinase mitochondrial 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0772_EXP_3 NADH kinase mitochondrial 0.7979123533471358 prot_Q06892 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0773 NADH:ubiquinone oxidoreductase 0.03180555555555555 prot_P32340 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 5.274105782675022 -r_0774 NAPRtase 62.59351652704193 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 0.0 +r_0774 NAPRtase 62.59351652704193 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 1.20000004244503e-07 r_0775 NAPRtase 54.465555555555554 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 0.0 r_0781 nicotinamidase 1.8269736842105264 prot_P53184 + H2O + nicotinamide --> ammonium + nicotinate 1.20000004244503e-07 r_0782 nicotinamide N-methyltransferase 130.92879390893637 prot_Q05874 + nicotinamide + S-adenosyl-L-methionine --> 1-methylnicotinamide + S-adenosyl-L-homocysteine 0.0 @@ -954,9 +954,9 @@ r_0783_EXP_1 nicotinamide-nucleotide adenylyltransferase 0.15292207792207793 pro r_0783_EXP_2 nicotinamide-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + NMN --> diphosphate + NAD 0.0 r_0784_EXP_1 nicotinamide-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + NMN --> diphosphate + NAD 0.0 r_0784_EXP_2 nicotinamide-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + NMN --> diphosphate + NAD 0.0 -r_0785_EXP_1 nicotinate-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0006071199974008957 +r_0785_EXP_1 nicotinate-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0006071199973977287 r_0785_EXP_2 nicotinate-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0 -r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0006071199974008957 +r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0006069999973934842 r_0787 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0 r_0788 nucleoside diphosphatase 0.25820037372430643 prot_P40009 + ADP + H2O --> AMP + H+ + phosphate 0.0 r_0789 nucleoside diphosphatase 0.19246758812814743 prot_P40009 + GDP + H2O --> GMP + H+ + phosphate 0.0 @@ -964,12 +964,12 @@ r_0790 nucleoside diphosphatase 0.24671061667353386 prot_P40009 + H2O + UDP --> r_0791 nucleoside diphosphatase 0.004121119814331302 prot_P32621 + H2O + UDP --> H+ + phosphate + UMP 0.0 r_0792 nucleoside diphosphatase 0.00661109270913842 prot_P40009 + CDP + H2O --> CMP + H+ + phosphate 0.0 r_0793 nucleoside diphosphatase 0.24979835905993603 prot_P40009 + H2O + IDP --> H+ + IMP + phosphate 0.0 -r_0795 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + CDP --> ADP + CTP 0.006311982029972546 +r_0795 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + CDP --> ADP + CTP 0.006311982030610281 r_0796 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dADP --> ADP + dATP 0.0 r_0797 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dCDP --> ADP + dCTP 0.0 r_0798 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dGDP --> ADP + dGTP 0.0 r_0799 nucleoside diphosphate kinase 0.3585421888053467 prot_P36010 + ATP + dTDP --> ADP + dTTP 0.0 -r_0800 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + GDP --> ADP + GTP 0.12585822151679302 +r_0800 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + GDP --> ADP + GTP 0.1258582215167948 r_0801 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + IDP --> ADP + ITP 0.0 r_0802 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dIDP --> ADP + dITP 0.0 r_0802_REV nucleoside diphosphate kinase (reversible) 0.3585421888053467 prot_P36010 + ADP + dITP --> ATP + dIDP 0.0 @@ -984,7 +984,7 @@ r_0807 nucleoside triphosphatase 0.00673132000048749 prot_P47119 + H2O + ITP --> r_0810 nucleoside-diphosphatase (GDP), Golgi 0.004121119814331302 prot_P32621 + GDP + H2O --> GMP + H+ + phosphate 0.0 r_0811 nucleoside-diphosphate kinase (ATP:UDP) 0.014855486327448944 prot_P36010 + ATP + UDP --> ADP + UTP 0.1546426239184487 r_0812 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + methanethiol + O-acetyl-L-homoserine --> acetate + H+ + L-methionine 0.0 -r_0813 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + hydrogen sulfide + O-acetyl-L-homoserine --> acetate + L-homocysteine 0.011924796613569698 +r_0813 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + hydrogen sulfide + O-acetyl-L-homoserine --> acetate + L-homocysteine 0.011924796613569717 r_0815_EXP_1 O-succinylhomoserine lyase (L-cysteine) 84.53345338034984 prot_Q12198 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 r_0815_EXP_2 O-succinylhomoserine lyase (L-cysteine) 0.170599173553719 prot_Q04533 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 r_0815_EXP_3 O-succinylhomoserine lyase (L-cysteine) 78.78148148148148 prot_P31373 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 @@ -997,46 +997,46 @@ r_0820_EXP_2 orotate phosphoribosyltransferase 5.301495726495727 prot_P30402 + d r_0820_REV_EXP_1 orotate phosphoribosyltransferase (reversible) 0.0019386279318367604 prot_P13298 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.010726833614579982 r_0820_REV_EXP_2 orotate phosphoribosyltransferase (reversible) 0.001950182355530403 prot_P30402 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.0 r_0821 orotidine-5'-phosphate decarboxylase 0.014249512670565302 prot_P03962 + H+ + orotidine 5'-(dihydrogen phosphate) --> carbon dioxide + UMP 0.010726833614579982 -r_0831_EXP_1 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.04684031538764905 prot_P09624 + 0.043736418169126635 prot_P19262 + 0.011871821465312496 prot_P19955 + 0.09922757869641279 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 1.483945717424315 +r_0831_EXP_1 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.04684031538764905 prot_P09624 + 0.043736418169126635 prot_P19262 + 0.011871821465312496 prot_P19955 + 0.09922757869641279 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 1.518442820796261 r_0831_EXP_2 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 0.0 -r_0832_EXP_1 oxoglutarate dehydrogenase (lipoamide) 0.023116760828625234 prot_P09624 + 0.021584916966272898 prot_P19262 + 0.005859013867488444 prot_P19955 + 0.048971066598185245 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 1.4839457174243147 +r_0832_EXP_1 oxoglutarate dehydrogenase (lipoamide) 0.023116760828625234 prot_P09624 + 0.021584916966272898 prot_P19262 + 0.005859013867488444 prot_P19955 + 0.048971066598185245 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 1.518442820796261 r_0832_EXP_2 oxoglutarate dehydrogenase (lipoamide) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 0.0 -r_0841 pantetheine-phosphate adenylyltransferase 1.9636765345605238 prot_P53332 + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 0.012651693810124875 -r_0842 pantothenate kinase 5.359407756813417 prot_Q04430 + (R)-pantothenate + ATP --> (R)-4'-phosphopantothenic acid + ADP + H+ 1.900000061125771e-05 -r_0843 pantothenate synthase 0.07626262626262627 prot_P40459 + (R)-pantoate + ATP + beta-alanine --> (R)-pantothenate + AMP + diphosphate + H+ 1.900000061125771e-05 +r_0841 pantetheine-phosphate adenylyltransferase 1.9636765345605238 prot_P53332 + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 0.012642418265246421 +r_0842 pantothenate kinase 5.359407756813417 prot_Q04430 + (R)-pantothenate + ATP --> (R)-4'-phosphopantothenic acid + ADP + H+ 1.9000000611286447e-05 +r_0843 pantothenate synthase 0.07626262626262627 prot_P40459 + (R)-pantoate + ATP + beta-alanine --> (R)-pantothenate + AMP + diphosphate + H+ 1.9000000611286447e-05 r_0844 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + decanoyl-CoA + H2O --> coenzyme A + decanoate + H+ 0.0 -r_0845 peroxisomal acyl-CoA thioesterase 1.1039815728858178 prot_P41903 + H2O + lauroyl-CoA --> coenzyme A + H+ + laurate 0.0005365495253866761 +r_0845 peroxisomal acyl-CoA thioesterase 1.1039815728858178 prot_P41903 + H2O + lauroyl-CoA --> coenzyme A + H+ + laurate 0.0 r_0847 peroxisomal acyl-CoA thioesterase 302.2522522522523 prot_P41903 + H2O + palmitoyl-CoA --> coenzyme A + H+ + palmitate 0.0 -r_0848 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + myristoyl-CoA --> coenzyme A + H+ + myristate 0.0002006987647042427 +r_0848 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + myristoyl-CoA --> coenzyme A + H+ + myristate 0.0 r_0849 peroxisomal acyl-CoA thioesterase 588.5964912280702 prot_P41903 + H2O + stearoyl-CoA --> coenzyme A + H+ + stearate 0.0 r_0850 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + octanoyl-CoA --> coenzyme A + H+ + octanoate 0.0 r_0851 phenylalanine transaminase 1.8801204819277106 prot_P53090 + 2-oxoglutarate + L-phenylalanine --> keto-phenylpyruvate + L-glutamate 0.0 -r_0851_REV phenylalanine transaminase (reversible) 0.550322030209992 prot_P53090 + keto-phenylpyruvate + L-glutamate --> 2-oxoglutarate + L-phenylalanine 0.063104185146981 +r_0851_REV phenylalanine transaminase (reversible) 0.550322030209992 prot_P53090 + keto-phenylpyruvate + L-glutamate --> 2-oxoglutarate + L-phenylalanine 0.06310418514697279 r_0852 phenylalanyl-tRNA synthetase 0.06206467661691542 prot_P15624 + 0.05298599594619495 prot_P15625 + ATP + L-phenylalanine + tRNA(Phe) --> AMP + diphosphate + Phe-tRNA(Phe) 0.016679595802671702 r_0853 phenylalanyl-tRNA synthetase 0.025257508752533627 prot_P08425 + ATP + L-phenylalanine + tRNA(Phe) --> AMP + diphosphate + Phe-tRNA(Phe) 0.0 r_0854 phenylpyruvate decarboxylase 0.9914444444444445 prot_Q06408 + H+ + keto-phenylpyruvate --> carbon dioxide + phenylacetaldehyde 0.0 -r_0855 phopshoribosylaminoimidazole synthetase 3.4153968253968254 prot_P07244 + 5'-phosphoribosyl-N-formylglycineamidine + ATP --> 5'-phosphoribosyl-5-aminoimidazole + ADP + H+ + phosphate 0.010240426385252575 +r_0855 phopshoribosylaminoimidazole synthetase 3.4153968253968254 prot_P07244 + 5'-phosphoribosyl-N-formylglycineamidine + ATP --> 5'-phosphoribosyl-5-aminoimidazole + ADP + H+ + phosphate 0.010240426385254225 r_0882 phosphoacetylglucosamine mutase 0.4264366394591475 prot_P38628 + N-acetyl-D-glucosamine 6-phosphate --> N-acetyl-alpha-D-glucosamine 1-phosphate 0.0023610000000000003 r_0882_REV phosphoacetylglucosamine mutase (reversible) 0.4264366394591475 prot_P38628 + N-acetyl-alpha-D-glucosamine 1-phosphate --> N-acetyl-D-glucosamine 6-phosphate 0.0 -r_0883_EXP_1 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8892063492063492 prot_P22803 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.012044165779709844 +r_0883_EXP_1 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8892063492063492 prot_P22803 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.011924916613573963 r_0883_EXP_2 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8916666666666667 prot_P22217 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.0 r_0884 phosphoenolpyruvate carboxykinase 0.27322132616487455 prot_P10963 + ATP + oxaloacetate --> ADP + carbon dioxide + phosphoenolpyruvate 0.0 r_0885 phosphoethanolamine cytidyltransferase 8.904106280193236 prot_P33412 + CTP + H+ + O-phosphoethanolamine --> CDP-ethanolamine + diphosphate 0.0 -r_0886 phosphofructokinase 0.06875388870533351 prot_P16861 + 0.06661937879572642 prot_P16862 + ATP + D-fructose 6-phosphate --> ADP + D-fructose 1,6-bisphosphate + H+ 3.2011841721513563 +r_0886 phosphofructokinase 0.06875388870533351 prot_P16861 + 0.06661937879572642 prot_P16862 + ATP + D-fructose 6-phosphate --> ADP + D-fructose 1,6-bisphosphate + H+ 3.2153982268262493 r_0888_EXP_1 phosphoglucomutase 0.08151033591731266 prot_P37012 + D-glucose 6-phosphate --> D-glucose 1-phosphate 0.147954 r_0888_EXP_2 phosphoglucomutase 0.08154005167958657 prot_P33401 + D-glucose 6-phosphate --> D-glucose 1-phosphate 0.0 r_0888_REV_EXP_1 phosphoglucomutase (reversible) 0.08151033591731266 prot_P37012 + D-glucose 1-phosphate --> D-glucose 6-phosphate 0.0 r_0888_REV_EXP_2 phosphoglucomutase (reversible) 0.08154005167958657 prot_P33401 + D-glucose 1-phosphate --> D-glucose 6-phosphate 0.0 r_0889_EXP_1 phosphogluconate dehydrogenase 0.41150030525030523 prot_P53319 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.0 -r_0889_EXP_2 phosphogluconate dehydrogenase 0.40860042735042734 prot_P38720 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 2.2864587827242655e-13 +r_0889_EXP_2 phosphogluconate dehydrogenase 0.40860042735042734 prot_P38720 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.0 r_0890 phosphoglucosamine mutase 0.4264366394591475 prot_P38628 + alpha-D-glucosamine 1-phosphate --> alpha-D-glucosamine 6-phosphate 0.0 r_0890_REV phosphoglucosamine mutase (reversible) 0.4264366394591475 prot_P38628 + alpha-D-glucosamine 6-phosphate --> alpha-D-glucosamine 1-phosphate 0.0 r_0891_EXP_1 phosphoglycerate dehydrogenase 0.0036935786435786434 prot_P40054 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.0 -r_0891_EXP_2 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.5281995575036499 -r_0892 phosphoglycerate kinase 0.02315487650870546 prot_P00560 + 1,3-bisphospho-D-glycerate + ADP --> 3-phosphonato-D-glycerate(3-) + ATP 6.204842484400544 +r_0891_EXP_2 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.5282364349358776 +r_0892 phosphoglycerate kinase 0.02315487650870546 prot_P00560 + 1,3-bisphospho-D-glycerate + ADP --> 3-phosphonato-D-glycerate(3-) + ATP 6.238551398891973 r_0892_REV phosphoglycerate kinase (reversible) 0.02315487650870546 prot_P00560 + 3-phosphonato-D-glycerate(3-) + ATP --> 1,3-bisphospho-D-glycerate + ADP 0.0 r_0893_EXP_1 phosphoglycerate mutase 1.1738045797601886 prot_Q12040 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 0.0 -r_0893_EXP_2 phosphoglycerate mutase 0.013314525462962964 prot_P00950 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 5.676642926896894 +r_0893_EXP_2 phosphoglycerate mutase 0.013314525462962964 prot_P00950 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 5.710314963956096 r_0893_REV_EXP_1 phosphoglycerate mutase (reversible) 2.640272344101795 prot_Q12040 + 2-phospho-D-glyceric acid --> 3-phosphonato-D-glycerate(3-) 0.0 r_0893_REV_EXP_2 phosphoglycerate mutase (reversible) 0.013314525462962964 prot_P00950 + 2-phospho-D-glyceric acid --> 3-phosphonato-D-glycerate(3-) 0.0 r_0902 phosphomannomutase 1.8347853535353533 prot_P07283 + D-mannose 1-phosphate --> D-mannose 6-phosphate 0.0 @@ -1044,33 +1044,33 @@ r_0902_REV phosphomannomutase (reversible) 0.40001070189485594 prot_P07283 + D-m r_0903_EXP_1 phosphomethylpyrimidine kinase 39.57945736434109 prot_Q08224 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 1.20000004244503e-07 r_0903_EXP_2 phosphomethylpyrimidine kinase 39.62144702842377 prot_Q08975 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 0.0 r_0903_EXP_3 phosphomethylpyrimidine kinase 695.1822835935426 prot_Q06490 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 0.0 -r_0904 phosphomevalonate kinase 4.122140522875817 prot_P24521 + (R)-5-phosphomevalonic acid + ATP --> (R)-5-diphosphomevalonic acid + ADP 0.02234772406386473 -r_0905 phosphopantothenate-cysteine ligase 4.010249042145594 prot_P40506 + (R)-4'-phosphopantothenic acid + CTP + L-cysteine --> CMP + diphosphate + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine 1.900000061125771e-05 -r_0906 phosphopantothenoylcysteine decarboxylase 5.98448275862069 prot_P36024 + 6.248850574712644 prot_P36076 + 7.054501915708812 prot_Q08438 + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine --> carbon dioxide + pantetheine 4'-phosphate 1.900000061125771e-05 +r_0904 phosphomevalonate kinase 4.122140522875817 prot_P24521 + (R)-5-phosphomevalonic acid + ATP --> (R)-5-diphosphomevalonic acid + ADP 0.022126459469172983 +r_0905 phosphopantothenate-cysteine ligase 4.010249042145594 prot_P40506 + (R)-4'-phosphopantothenic acid + CTP + L-cysteine --> CMP + diphosphate + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine 1.9000000611286447e-05 +r_0906 phosphopantothenoylcysteine decarboxylase 5.98448275862069 prot_P36024 + 6.248850574712644 prot_P36076 + 7.054501915708812 prot_Q08438 + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine --> carbon dioxide + pantetheine 4'-phosphate 1.9000000611286447e-05 r_0907_EXP_1 phosphopentomutase 0.08154005167958657 prot_P33401 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_EXP_2 phosphopentomutase 0.08151033591731266 prot_P37012 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_EXP_3 phosphopentomutase 0.10671021021021021 prot_Q03262 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_REV_EXP_1 phosphopentomutase (reversible) 0.08154005167958657 prot_P33401 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0 r_0907_REV_EXP_2 phosphopentomutase (reversible) 0.08151033591731266 prot_P37012 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0012297510243303755 r_0907_REV_EXP_3 phosphopentomutase (reversible) 0.10671021021021021 prot_Q03262 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0 -r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.17755272474518155 prot_P27616 + ATP + L-aspartate + phosphoribosyl-carboxy-aminoimidazole --> 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + 2.0 H+ + phosphate 0.01024030638524833 +r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.17755272474518155 prot_P27616 + ATP + L-aspartate + phosphoribosyl-carboxy-aminoimidazole --> 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + 2.0 H+ + phosphate 0.01024030638524998 r_0909 phosphoribosyl-AMP cyclohydrolase 0.00852140040022537 prot_P00815 + 1-(5-phosphoribosyl)-5'-AMP + H2O --> 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide 0.008356708763266002 r_0910 phosphoribosyl-ATP pyrophosphatase 6.601766492974471 prot_P00815 + 5-phosphoribosyl-ATP + H2O --> 1-(5-phosphoribosyl)-5'-AMP + diphosphate + H+ 0.008356708763266002 -r_0911 phosphoribosylaminoimidazole-carboxylase 0.2248881673881674 prot_P21264 + 5'-phosphoribosyl-5-aminoimidazole + carbon dioxide --> H+ + phosphoribosyl-carboxy-aminoimidazole 0.01024030638524833 +r_0911 phosphoribosylaminoimidazole-carboxylase 0.2248881673881674 prot_P21264 + 5'-phosphoribosyl-5-aminoimidazole + carbon dioxide --> H+ + phosphoribosyl-carboxy-aminoimidazole 0.01024030638524998 r_0912_EXP_1 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.10859173126615 prot_P54113 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.0 -r_0912_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.1079780361757106 prot_P38009 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.018597015148514334 +r_0912_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.1079780361757106 prot_P38009 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.018597015148515982 r_0912_REV_EXP_1 phosphoribosylaminoimidazolecarboxamide formyltransferase (reversible) 2.10859173126615 prot_P54113 + phosphoribosyl-formamido-carboxamide + THF --> 10-formyl-THF + AICAR 0.0 r_0912_REV_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase (reversible) 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide + THF --> 10-formyl-THF + AICAR 0.0 -r_0913 phosphoribosylanthranilate isomerase 0.09719806763285024 prot_P00912 + N-(5-phospho-beta-D-ribosyl)anthranilate --> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 0.004508621257677621 -r_0914 phosphoribosylglycinamidine synthetase 3.4153968253968254 prot_P07244 + 5-phosphoribosylamine + ATP + L-glycine --> 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate 0.010240426385252575 -r_0915 phosphoribosylpyrophosphate amidotransferase 0.28336830535571544 prot_P04046 + H2O + L-glutamine + PRPP --> 5-phosphoribosylamine + diphosphate + L-glutamate 0.010240426385252575 -r_0916_EXP_1 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11565202927478377 prot_P38620 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.03443971001817707 +r_0913 phosphoribosylanthranilate isomerase 0.09719806763285024 prot_P00912 + N-(5-phospho-beta-D-ribosyl)anthranilate --> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 0.004508621257685833 +r_0914 phosphoribosylglycinamidine synthetase 3.4153968253968254 prot_P07244 + 5-phosphoribosylamine + ATP + L-glycine --> 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate 0.010240426385254225 +r_0915 phosphoribosylpyrophosphate amidotransferase 0.28336830535571544 prot_P04046 + H2O + L-glutamine + PRPP --> 5-phosphoribosylamine + diphosphate + L-glutamate 0.010240426385254225 +r_0916_EXP_1 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11565202927478377 prot_P38620 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.03443971001818376 r_0916_EXP_2 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11684630738522954 prot_P38689 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_3 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11882900864936793 prot_P38063 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_4 phosphoribosylpyrophosphate synthetase 0.11565202927478377 prot_P38620 + 0.17799401197604792 prot_Q12265 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_5 phosphoribosylpyrophosphate synthetase 0.11882900864936793 prot_P38063 + 0.17799401197604792 prot_Q12265 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 -r_0917 phosphoserine phosphatase (L-serine) 0.006309392061384094 prot_P42941 + 3-phospho-serine + H2O --> L-serine + phosphate 0.5281995575036499 -r_0918 phosphoserine transaminase 4.103165485515034 prot_P33330 + 3-phospho-hydroxypyruvate + L-glutamate --> 2-oxoglutarate + 3-phospho-serine 0.5281995575036499 +r_0917 phosphoserine phosphatase (L-serine) 0.006309392061384094 prot_P42941 + 3-phospho-serine + H2O --> L-serine + phosphate 0.5282364349358776 +r_0918 phosphoserine transaminase 4.103165485515034 prot_P33330 + 3-phospho-hydroxypyruvate + L-glutamate --> 2-oxoglutarate + 3-phospho-serine 0.5282364349358776 r_0919 phytoceramidase 13.387690165065315 prot_P38298 + lignoceric acid + phytosphingosine --> ceramide-2 (C24) + H2O 0.0 r_0920 phytoceramidase 107.0999354737445 prot_P21595 + cerotic acid + phytosphingosine --> ceramide-2 (C26) + H2O 0.0 r_0921 Phytosphingosine phosphate lyase 82.78535353535354 prot_Q05567 + phytosphingosine 1-phosphate --> 2-hydroxyhexadecanal + O-phosphoethanolamine 0.0 @@ -1080,7 +1080,7 @@ r_0935 porphobilinogen synthase 1.9935529153386848 prot_P05373 + 2.0 5-aminolevu r_0936 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + N(1)-acetylspermine + oxygen --> 3-aminopropanal + hydrogen peroxide + N(1)-acetylspermidine 0.0 r_0937 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + oxygen + spermine --> 3-aminopropanal + hydrogen peroxide + spermidine 0.0012297510243303755 r_0938 prephenate dehydratase 0.012934651669576752 prot_P32452 + H+ + prephenate --> carbon dioxide + H2O + keto-phenylpyruvate 0.016679595802671702 -r_0939 prephenate dehydrogenase (NADP) 0.537843261512463 prot_P20049 + NAD + prephenate --> 3-(4-hydroxyphenyl)pyruvate + carbon dioxide + NADH 0.05494461010374542 +r_0939 prephenate dehydrogenase (NADP) 0.537843261512463 prot_P20049 + NAD + prephenate --> 3-(4-hydroxyphenyl)pyruvate + carbon dioxide + NADH 0.012302566079285501 r_0940 proline oxidase (NAD) 0.44171641791044775 prot_P09368 + FAD + L-proline --> 1-pyrroline-5-carboxylate + FADH2 0.0 r_0941 prolyl-tRNA synthetase 3.83859126984127 prot_P38708 + ATP + L-proline + tRNA(Pro) --> AMP + diphosphate + Pro-tRNA(Pro) 0.0179821149401597 r_0942 protoporphyrinogen oxidase 34.59572043825653 prot_P40012 + 3.0 oxygen + 2.0 protoporphyrinogen --> 6.0 H2O + 2.0 protoporphyrin 0.0 @@ -1094,18 +1094,18 @@ r_0951_REV inosine phosphorylase (reversible) 0.07382983377077865 prot_Q05788 + r_0953 pyridoxal oxidase 10.677777777777777 prot_P38075 + ammonium + 2.0 H2O + 0.5 oxygen + pyridoxal --> 2.0 hydrogen peroxide + pyridoxamine 0.0 r_0954 pyridoxamine 5'-phosphate oxidase 72.56742179072278 prot_P38075 + H2O + oxygen + pyridoxamine 5'-phosphate --> ammonium + hydrogen peroxide + pyridoxal 5'-phosphate 0.0 r_0955 pyridoxine 5'-phosphate oxidase 10.677777777777777 prot_P38075 + oxygen + pyridoxine 5'-phosphate --> hydrogen peroxide + pyridoxal 5'-phosphate 0.0 -r_0956 pyridoxine oxidase 10.677777777777777 prot_P38075 + oxygen + pyridoxine --> hydrogen peroxide + pyridoxal 0.00322309999869854 +r_0956 pyridoxine oxidase 10.677777777777777 prot_P38075 + oxygen + pyridoxine --> hydrogen peroxide + pyridoxal 0.0 r_0957 pyrroline-5-carboxylate reductase 0.0020925 prot_P32263 + 1-pyrroline-5-carboxylate + 2.0 H+ + NADPH --> L-proline + NADP(+) 0.0179821149401597 -r_0958_EXP_1 pyruvate carboxylase 0.602625 prot_P32327 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.05161953775775707 +r_0958_EXP_1 pyruvate carboxylase 0.602625 prot_P32327 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.12032539157161479 r_0958_EXP_2 pyruvate carboxylase 0.6023101851851852 prot_P11154 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.3378128102989236 r_0959_EXP_1 pyruvate decarboxylase 0.27589605734767025 prot_P26263 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.0 -r_0959_EXP_2 pyruvate decarboxylase 0.08176022088979121 prot_P06169 + H+ + pyruvate --> acetaldehyde + carbon dioxide 4.578308619409206 +r_0959_EXP_2 pyruvate decarboxylase 0.08176022088979121 prot_P06169 + H+ + pyruvate --> acetaldehyde + carbon dioxide 3.258366142800424 r_0959_EXP_3 pyruvate decarboxylase 0.27738351254480287 prot_P16467 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.0 r_0960_EXP_1 pyruvate decarboxylase (acetoin-forming) 0.27589605734767025 prot_P26263 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 r_0960_EXP_2 pyruvate decarboxylase (acetoin-forming) 0.11780651340996169 prot_P06169 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 r_0960_EXP_3 pyruvate decarboxylase (acetoin-forming) 0.27738351254480287 prot_P16467 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 -r_0961 pyruvate dehydrogenase 0.23664570803230708 prot_P09624 + 1.1352071189426114 prot_P12695 + 0.4061052415234663 prot_P16387 + 0.19875435304131667 prot_P16451 + 0.35099452655160257 prot_P32473 + coenzyme A + NAD + pyruvate --> acetyl-CoA + carbon dioxide + NADH 0.21149421691811088 -r_0962_EXP_1 pyruvate kinase 0.06530771072796934 prot_P00549 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 5.524453632197057 +r_0961 pyruvate dehydrogenase 0.23664570803230708 prot_P09624 + 1.1352071189426114 prot_P12695 + 0.4061052415234663 prot_P16387 + 0.19875435304131667 prot_P16451 + 0.35099452655160257 prot_P32473 + coenzyme A + NAD + pyruvate --> acetyl-CoA + carbon dioxide + NADH 1.6645088744526975 +r_0962_EXP_1 pyruvate kinase 0.06530771072796934 prot_P00549 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 5.643409997305193 r_0962_EXP_2 pyruvate kinase 0.06608596743295019 prot_P52489 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 0.0 r_0963 quinone oxidoreductase 0.2834173315594083 prot_O13525 + 0.266570923780901 prot_P27680 + 0.191209663200305 prot_P41735 + 0.2544937516539746 prot_P49017 + 0.39274288726487816 prot_P53318 + 0.21981040253855474 prot_Q05779 + 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + NADH + oxygen --> 2-hexaprenyl-5-hydroxy-6-methoxy-3-methyl-1,4-benzoquinone + H2O + NAD 0.0 r_0964 reduced glutathione via ABC system 161.4141633681904 prot_P39109 + ATP + glutathione + H2O --> ADP + glutathione + H+ + phosphate 0.0 @@ -1142,13 +1142,13 @@ r_0979_EXP_1 ribonucleotide reductase 2.143863049095607 prot_P21524 + GDP + H+ + r_0979_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 r_0979_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 r_0979_EXP_4 ribonucleotide reductase 0.9936907838070629 prot_P09938 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 -r_0982 ribose-5-phosphate isomerase 0.5468480156600358 prot_Q12189 + D-ribulose 5-phosphate --> ribose-5-phosphate 0.04907785648031397 +r_0982 ribose-5-phosphate isomerase 0.5468480156600358 prot_Q12189 + D-ribulose 5-phosphate --> ribose-5-phosphate 0.03486380180541987 r_0982_REV ribose-5-phosphate isomerase (reversible) 0.817650462962963 prot_Q12189 + ribose-5-phosphate --> D-ribulose 5-phosphate 0.0 r_0983 ribosylnicotinamide kinase 4.5245098039215685 prot_P53915 + ATP + nicotinamide riboside --> ADP + H+ + NMN 0.0 r_0984 ribulose 5-phosphate 3-epimerase 0.06355115026921195 prot_P46969 + D-ribulose 5-phosphate --> D-xylulose 5-phosphate 0.0 -r_0984_REV ribulose 5-phosphate 3-epimerase (reversible) 0.06355115026921195 prot_P46969 + D-xylulose 5-phosphate --> D-ribulose 5-phosphate 0.0492778564743053 +r_0984_REV ribulose 5-phosphate 3-epimerase (reversible) 0.06355115026921195 prot_P46969 + D-xylulose 5-phosphate --> D-ribulose 5-phosphate 0.035063801799639846 r_0985 S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase 0.55303275478674 prot_O13525 + 0.5201603286342985 prot_P27680 + 0.37310776373372107 prot_P41735 + 0.49659412068703435 prot_P49017 + 0.7663599105669565 prot_P53318 + 0.42891643844723004 prot_Q05779 + 3-hexaprenyl-4,5-dihydroxybenzoic acid + S-adenosyl-L-methionine --> 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid + H+ + S-adenosyl-L-homocysteine 0.0 -r_0986 S-adenosyl-methionine delta-24-sterol-c-methyltransferase 1096.7424242424245 prot_P25087 + S-adenosyl-L-methionine + zymosterol --> fecosterol + H+ + S-adenosyl-L-homocysteine 0.00024360249435691642 +r_0986 S-adenosyl-methionine delta-24-sterol-c-methyltransferase 1096.7424242424245 prot_P25087 + S-adenosyl-L-methionine + zymosterol --> fecosterol + H+ + S-adenosyl-L-homocysteine 0.0 r_0987 S-formylglutathione hydralase 0.3307407407407407 prot_P40363 + H2O + S-formylglutathione --> formate + glutathione + H+ 0.0 r_0988 saccharopine dehydrogenase (NAD, L-lysine forming) 0.6126625295508275 prot_P38998 + H2O + L-saccharopine + NAD --> 2-oxoglutarate + H+ + L-lysine + NADH 0.032939964005654 r_0989 saccharopine dehydrogenase (NADP, L-glutamate forming) 0.2203315572298126 prot_P38999 + H+ + L-allysine + L-glutamate + NADPH --> H2O + L-saccharopine + NADP(+) 0.032939964005654 @@ -1158,8 +1158,8 @@ r_0992 serine O-acetyltransferase 17.435821109618253 prot_P07347 + 62.4747269081 r_0993 serine palmitotransferase 11.220598845598845 prot_P25045 + 12.829184704184705 prot_P32368 + 11.383658008658008 prot_P40970 + 4.553571428571429 prot_P53224 + 4.483225108225108 prot_Q06144 + 1.727813852813853 prot_Q3E790 + H+ + L-serine + palmitoyl-CoA --> 3-ketosphinganine + carbon dioxide + coenzyme A 0.0 r_0995_EXP_1 seryl-tRNA synthetase 3.797008547008547 prot_P07284 + ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + Ser-tRNA(Ser) 0.027154748203566278 r_0995_EXP_2 seryl-tRNA synthetase 3.589031339031339 prot_P38705 + ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + Ser-tRNA(Ser) 0.0006178176947389265 -r_0996 shikimate dehydrogenase 0.12478934590117109 prot_P08566 + 3-dehydroshikimate + H+ + NADPH --> NADP(+) + shikimate 0.07609464734991835 -r_0997 shikimate kinase 0.1645527306967985 prot_P08566 + ATP + shikimate --> 3-phosphoshikimic acid + ADP + H+ 0.07609464734991835 +r_0996 shikimate dehydrogenase 0.12478934590117109 prot_P08566 + 3-dehydroshikimate + H+ + NADPH --> NADP(+) + shikimate 0.033452483325451324 +r_0997 shikimate kinase 0.1645527306967985 prot_P08566 + ATP + shikimate --> 3-phosphoshikimic acid + ADP + H+ 0.033452483325451324 r_0998 sirohydrochlorin dehydrogenase 147.7685185185185 prot_P15807 + NAD + precorrin-2 --> 2.0 H+ + NADH + sirohydrochlorin 0.0 r_0999 sirohydrochlorin ferrochetalase 147.7685185185185 prot_P15807 + iron(2+) + sirohydrochlorin --> 2.0 H+ + siroheme 0.0 r_1000 fumarate reductase (FMN) 0.9170995670995671 prot_P32614 + FMNH2 + fumarate --> FMN + H+ + succinate 0.0 @@ -1180,23 +1180,23 @@ r_1008_REV spontaneous cis-aconitate(3-) to trans-aconitate (reversible) 1.13290 r_1009 spontaneous cis-aconitate(3-) to trans-aconitate 1.1329040404040405 prot_standard + cis-aconitate --> trans-aconitate 0.0 r_1009_REV spontaneous cis-aconitate(3-) to trans-aconitate (reversible) 1.1329040404040405 prot_standard + trans-aconitate --> cis-aconitate 0.0 r_1010 squalene epoxidase (NAD) 201.483918128655 prot_P32476 + H+ + NADH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NAD 0.0 -r_1011 squalene epoxidase (NADP) 161.16753104520652 prot_P32476 + H+ + NADPH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NADP(+) 0.0037246206773107857 -r_1012 squalene synthase 8.707070707070708 prot_P29704 + 2.0 farnesyl diphosphate + H+ + NADPH --> 2.0 diphosphate + NADP(+) + squalene 0.0037246206773107857 +r_1011 squalene epoxidase (NADP) 161.16753104520652 prot_P32476 + H+ + NADPH + oxygen + squalene --> (S)-2,3-epoxysqualene + H2O + NADP(+) 0.003687743244862164 +r_1012 squalene synthase 8.707070707070708 prot_P29704 + 2.0 farnesyl diphosphate + H+ + NADPH --> 2.0 diphosphate + NADP(+) + squalene 0.003687743244862164 r_1021_EXP_1 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07412606837606837 prot_P47052 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.0 -r_1021_EXP_2 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07503098290598291 prot_Q00711 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.5260531226610423 -r_1021_EXP_3 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.07412606837606837 prot_P47052 + 0.019905982905982906 prot_Q06236 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.9928393610645959 +r_1021_EXP_2 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07503098290598291 prot_Q00711 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.0 +r_1021_EXP_3 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.07412606837606837 prot_P47052 + 0.019905982905982906 prot_Q06236 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 1.5536165706799971 r_1021_REV_EXP_1 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.022498888888888888 prot_P37298 + 0.07709111111111111 prot_P47052 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 r_1021_REV_EXP_2 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.022498888888888888 prot_P37298 + 0.07803222222222223 prot_Q00711 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 r_1021_REV_EXP_3 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.07709111111111111 prot_P47052 + 0.020702222222222223 prot_Q06236 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 -r_1022 succinate-CoA ligase (ADP-forming) 0.06481619679380873 prot_P53312 + 0.048413488114980655 prot_P53598 + ADP + phosphate + succinyl-CoA --> ATP + coenzyme A + succinate 0.0 -r_1023 succinate-semialdehyde dehydrogenase (NADP) 0.6660398230088496 prot_P38067 + H2O + NADP(+) + succinic semialdehyde --> 2.0 H+ + NADPH + succinate 0.0 +r_1022 succinate-CoA ligase (ADP-forming) 0.06481619679380873 prot_P53312 + 0.048413488114980655 prot_P53598 + ADP + phosphate + succinyl-CoA --> ATP + coenzyme A + succinate 1.4469339103442098 +r_1023 succinate-semialdehyde dehydrogenase (NADP) 0.6660398230088496 prot_P38067 + H2O + NADP(+) + succinic semialdehyde --> 2.0 H+ + NADPH + succinate 0.00022698358235192912 r_1024 sucrose hydrolyzing enzyme 0.004910835762876579 prot_P00724 + H2O + sucrose --> D-fructose + D-glucose 0.0 -r_1025 sulfate adenylyltransferase 0.6571607468123861 prot_P08536 + ATP + H+ + sulphate --> 5'-adenylyl sulfate + diphosphate 0.012044165779709846 +r_1025 sulfate adenylyltransferase 0.6571607468123861 prot_P08536 + ATP + H+ + sulphate --> 5'-adenylyl sulfate + diphosphate 0.011924916613573963 r_1026 sulfate adenylyltransferase (ADP) 0.10559317129629629 prot_P16550 + 5'-adenylyl sulfate + phosphate --> ADP + H+ + sulphate 0.0 -r_1027 sulfite reductase (NADPH2) 0.4089351851851852 prot_P39692 + 0.574141737891738 prot_P47169 + 4.0 H+ + 3.0 NADPH + sulphite --> 3.0 H2O + hydrogen sulfide + 3.0 NADP(+) 0.012044165779709846 +r_1027 sulfite reductase (NADPH2) 0.4089351851851852 prot_P39692 + 0.574141737891738 prot_P47169 + 4.0 H+ + 3.0 NADPH + sulphite --> 3.0 H2O + hydrogen sulfide + 3.0 NADP(+) 0.011924916613573963 r_1028 taurcholate via ABC system 571.7858889359086 prot_P32386 + ATP + H2O + taurocholate --> ADP + H+ + phosphate + taurocholate 0.0 r_1029 taurine dioxygenase 0.6971220085126848 prot_Q12358 + 2-oxoglutarate + oxygen + taurine --> aminoacetaldehyde + carbon dioxide + H+ + succinate + sulphite 0.0 -r_1030 tetrahydrofolate aminomethyltransferase 0.12487609595740357 prot_P09624 + 0.0434511474046933 prot_P39726 + 0.10281642494222884 prot_P48015 + 0.2646212564047546 prot_P49095 + 5,10-methenyl-THF + H2O --> 5-formyltetrahydrofolic acid + H+ 0.185902952616447 +r_1030 tetrahydrofolate aminomethyltransferase 0.12487609595740357 prot_P09624 + 0.0434511474046933 prot_P39726 + 0.10281642494222884 prot_P48015 + 0.2646212564047546 prot_P49095 + 5,10-methenyl-THF + H2O --> 5-formyltetrahydrofolic acid + H+ 1.071652654634107 r_1031_EXP_1 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) 6.686527777777778 prot_P36001 + ATP + L-glutamate + THF --> 5,6,7,8-tetrahydrofolyl-L-glutamic acid + ADP + H+ + phosphate 0.0 r_1031_EXP_2 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) 8.632083333333334 prot_Q08645 + ATP + L-glutamate + THF --> 5,6,7,8-tetrahydrofolyl-L-glutamic acid + ADP + H+ + phosphate 0.0 r_1031_REV_EXP_1 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) (reversible) 6.686527777777778 prot_P36001 + 5,6,7,8-tetrahydrofolyl-L-glutamic acid + ADP + H+ + phosphate --> ATP + L-glutamate + THF 0.0 @@ -1210,7 +1210,7 @@ r_1037_EXP_1 thioredoxin 0.16380116959064328 prot_P22803 + 0.3526315789473684 pr r_1037_EXP_2 thioredoxin 0.1642543859649123 prot_P22217 + 0.3526315789473684 prot_P40553 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_1038_EXP_1 thioredoxin reductase (NADPH) 0.09346012679346014 prot_P22803 + 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1038_EXP_2 thioredoxin reductase (NADPH) 0.09371871871871873 prot_P22217 + 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 -r_1038_EXP_3 thioredoxin reductase (NADPH) 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.019965864985636367 +r_1038_EXP_3 thioredoxin reductase (NADPH) 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.013124916624004775 r_1039_EXP_1 thioredoxin reductase (NADPH) 0.12038705372038706 prot_P25372 + 0.3093677010343677 prot_P38816 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1039_EXP_2 thioredoxin reductase (NADPH) 0.004454320987654321 prot_P25372 + 0.016494135802469136 prot_P41921 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1040 threonine aldolase 0.2765826873385013 prot_P37303 + L-threonine --> acetaldehyde + L-glycine 0.0 @@ -1221,22 +1221,22 @@ r_1045 thymidylate synthase 0.20281828703703703 prot_P06785 + 5,10-methylenetetr r_1046 trans-aconitate 3-methyltransferase 147.17240726195595 prot_P32643 + S-adenosyl-L-methionine + trans-aconitate --> (2E)-3-(methoxycarbonyl)pent-2-enedioic acid + S-adenosyl-L-homocysteine 0.0 r_1047 trans-pentaprenyltranstransferase 1.43565817535086 prot_P18900 + isopentenyl diphosphate + pentaprenyl diphosphate --> diphosphate + hexaprenyl diphosphate 0.0 r_1048_EXP_1 transaldolase 0.796025641025641 prot_P53228 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.0 -r_1048_EXP_2 transaldolase 0.13717037037037036 prot_P15019 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.013408395437806524 +r_1048_EXP_2 transaldolase 0.13717037037037036 prot_P15019 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.0 r_1048_REV_EXP_1 transaldolase (reversible) 0.4518922852983988 prot_P53228 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 -r_1048_REV_EXP_2 transaldolase (reversible) 0.13717037037037036 prot_P15019 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 +r_1048_REV_EXP_2 transaldolase (reversible) 0.13717037037037036 prot_P15019 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0008056592370942611 r_1049_EXP_1 transketolase 1 0.30204911433172305 prot_P33315 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 -r_1049_EXP_2 transketolase 1 0.2971256038647343 prot_P23254 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.013408395437806524 +r_1049_EXP_2 transketolase 1 0.2971256038647343 prot_P23254 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 r_1049_REV_EXP_1 transketolase 1 (reversible) 0.30204911433172305 prot_P33315 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0 -r_1049_REV_EXP_2 transketolase 1 (reversible) 0.2971256038647343 prot_P23254 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0 +r_1049_REV_EXP_2 transketolase 1 (reversible) 0.2971256038647343 prot_P23254 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0008056592370942611 r_1050_EXP_1 transketolase 2 0.30204911433172305 prot_P33315 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.0 r_1050_EXP_2 transketolase 2 0.2971256038647343 prot_P23254 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.0 r_1050_REV_EXP_1 transketolase 2 (reversible) 0.30204911433172305 prot_P33315 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.0 -r_1050_REV_EXP_2 transketolase 2 (reversible) 0.2971256038647343 prot_P23254 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.06268625191211182 +r_1050_REV_EXP_2 transketolase 2 (reversible) 0.2971256038647343 prot_P23254 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.034258142562545585 r_1051_EXP_1 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5532575757575757 prot_P38427 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.0 r_1051_EXP_2 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5004419191919192 prot_P38426 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.013655 -r_1054 triose-phosphate isomerase 0.0008592271925605259 prot_P00942 + dihydroxyacetone phosphate --> glyceraldehyde 3-phosphate 3.061835942903521 +r_1054 triose-phosphate isomerase 0.0008592271925605259 prot_P00942 + dihydroxyacetone phosphate --> glyceraldehyde 3-phosphate 3.052902693370584 r_1054_REV triose-phosphate isomerase (reversible) 0.0008592271925605259 prot_P00942 + glyceraldehyde 3-phosphate --> dihydroxyacetone phosphate 0.0 -r_1055 tryptophan synthase (indoleglycerol phosphate) 0.43168564547057753 prot_P00931 + 1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> glyceraldehyde 3-phosphate + H2O + L-tryptophan 0.004508621257677621 +r_1055 tryptophan synthase (indoleglycerol phosphate) 0.43168564547057753 prot_P00931 + 1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> glyceraldehyde 3-phosphate + H2O + L-tryptophan 0.004508621257685833 r_1056 tryptophan transaminase 1.2484 prot_P53090 + 2-oxoglutarate + L-tryptophan --> indole-3-pyruvate + L-glutamate 0.0 r_1057 tryptophanyl-tRNA synthetase 0.5595238095238095 prot_Q12109 + ATP + L-tryptophan + tRNA(Trp) --> AMP + diphosphate + Trp-tRNA(Trp) 0.0038569814458458205 r_1058 tryptophanyl-tRNA synthetase 0.4876984126984127 prot_P04803 + ATP + L-tryptophan + tRNA(Trp) --> AMP + diphosphate + Trp-tRNA(Trp) 0.0 @@ -1252,7 +1252,7 @@ r_1070 UDPglucose 4-epimerase 0.532373366013072 prot_P04397 + UDP-D-glucose --> r_1070_REV UDPglucose 4-epimerase (reversible) 0.532373366013072 prot_P04397 + UDP-D-galactose --> UDP-D-glucose 0.0 r_1071 UDPglucose--hexose-1-phosphate uridylyltransferase 0.3270447530864197 prot_P08431 + alpha-D-galactose 1-phosphate + UDP-D-glucose --> D-glucose 1-phosphate + UDP-D-galactose 0.0 r_1071_REV UDPglucose--hexose-1-phosphate uridylyltransferase (reversible) 0.3270447530864197 prot_P08431 + D-glucose 1-phosphate + UDP-D-galactose --> alpha-D-galactose 1-phosphate + UDP-D-glucose 0.0 -r_1072 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.004927623923664102 +r_1072 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.004927623923664103 r_1073 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.0 r_1074 uracil phosphoribosyltransferase 1.1199453551912568 prot_P18562 + PRPP + uracil --> diphosphate + UMP 0.0 r_1075 urea carboxylase 0.26596036263967954 prot_P32528 + ATP + bicarbonate + urea --> ADP + H+ + phosphate + urea-1-carboxylic acid 0.0 @@ -1274,10 +1274,10 @@ r_1085_EXP_1 V-ATPase, Golgi 0.0066673789173789175 prot_P0C5R9 + 0.1233952991452 r_1085_EXP_2 V-ATPase, Golgi 0.04113176638176638 prot_P16140 + 0.08449928774928775 prot_P17255 + 0.018853988603988604 prot_P22203 + 0.016094017094017095 prot_P23968 + 0.011646011396011397 prot_P25515 + 0.03147364672364673 prot_P31412 + 0.02834116809116809 prot_P32366 + 0.020793447293447294 prot_P32610 + 0.012134615384615384 prot_P32842 + 0.07240811965811966 prot_P37296 + 0.009587606837606838 prot_P39111 + 0.03875783475783476 prot_P41807 + 0.009054843304843305 prot_P48836 + 0.021138176638176638 prot_P53262 + 0.005969373219373219 prot_Q3E7B6 + ATP + H+ + H2O --> ADP + 2.0 H+ + phosphate 0.0 r_1086_EXP_1 V-ATPase, vacuole 0.0066673789173789175 prot_P0C5R9 + 0.12339529914529915 prot_P16140 + 0.2534978632478633 prot_P17255 + 0.05656196581196581 prot_P22203 + 0.016094017094017095 prot_P23968 + 0.09316809116809117 prot_P25515 + 0.03147364672364673 prot_P31412 + 0.02834116809116809 prot_P32366 + 0.06804059829059829 prot_P32563 + 0.020793447293447294 prot_P32610 + 0.012134615384615384 prot_P32842 + 0.009587606837606838 prot_P39111 + 0.03875783475783476 prot_P41807 + 0.027164529914529913 prot_P48836 + 0.021138176638176638 prot_P53262 + 0.005969373219373219 prot_Q3E7B6 + ATP + H+ + H2O --> ADP + 2.0 H+ + phosphate 0.0 r_1086_EXP_2 V-ATPase, vacuole 0.04113176638176638 prot_P16140 + 0.08449928774928775 prot_P17255 + 0.018853988603988604 prot_P22203 + 0.016094017094017095 prot_P23968 + 0.011646011396011397 prot_P25515 + 0.03147364672364673 prot_P31412 + 0.02834116809116809 prot_P32366 + 0.06804059829059829 prot_P32563 + 0.020793447293447294 prot_P32610 + 0.012134615384615384 prot_P32842 + 0.009587606837606838 prot_P39111 + 0.03875783475783476 prot_P41807 + 0.009054843304843305 prot_P48836 + 0.021138176638176638 prot_P53262 + 0.005969373219373219 prot_Q3E7B6 + ATP + H+ + H2O --> ADP + 2.0 H+ + phosphate 0.0 -r_1087 valine transaminase 0.009354773462783171 prot_P47176 + 2-oxoglutarate + L-valine --> 3-methyl-2-oxobutanoate + L-glutamate 0.2382298330739352 +r_1087 valine transaminase 0.009354773462783171 prot_P47176 + 2-oxoglutarate + L-valine --> 3-methyl-2-oxobutanoate + L-glutamate 0.22142449525717553 r_1087_REV valine transaminase (reversible) 0.010755813953488373 prot_P47176 + 3-methyl-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-valine 0.0 r_1088 valine transaminase, mitochondiral 0.009797734627831714 prot_P38891 + 2-oxoglutarate + L-valine --> 3-methyl-2-oxobutanoate + L-glutamate 0.0 -r_1088_REV valine transaminase, mitochondiral (reversible) 0.011265116279069768 prot_P38891 + 3-methyl-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-valine 0.2696902880514212 +r_1088_REV valine transaminase, mitochondiral (reversible) 0.011265116279069768 prot_P38891 + 3-methyl-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-valine 0.2528849502346615 r_1089 valyl-tRNA synthetase 0.6987222222222222 prot_P07806 + ATP + L-valine + tRNA(Val) --> AMP + diphosphate + Val-tRNA(Val) 0.031460454977486 r_1090 valyl-tRNA synthetase 0.6987222222222222 prot_P07806 + ATP + L-valine + tRNA(Val) --> AMP + diphosphate + Val-tRNA(Val) 0.0 r_1091 xanthine phosphoribosyltransferase 1.5042841315863547 prot_P47165 + 9H-xanthine + PRPP --> diphosphate + xanthosine-5-phosphate 0.0 @@ -1319,17 +1319,17 @@ r_1108_EXP_2 adenine transport 96.43325000488205 prot_P40039 + adenine + H+ --> r_1108_EXP_3 adenine transport 170.37838815188596 prot_Q12119 + adenine + H+ --> adenine + H+ 0.0 r_1109 adenosine transport 38.061322453849215 prot_P31381 + adenosine + H+ --> adenosine + H+ 0.0 r_1110_EXP_1 ADP/ATP transporter 0.06555300613384876 prot_P18239 + ADP + ATP --> ADP + ATP 0.0 -r_1110_EXP_2 ADP/ATP transporter 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 14.140674383908964 +r_1110_EXP_2 ADP/ATP transporter 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 15.453697143590752 r_1110_EXP_3 ADP/ATP transporter 0.045422922213833025 prot_P04710 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_1 ADP/ATP transporter (reversible) 0.06555300613384876 prot_P18239 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_2 ADP/ATP transporter (reversible) 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_3 ADP/ATP transporter (reversible) 0.045422922213833025 prot_P04710 + ADP + ATP --> ADP + ATP 0.0 r_1111 ADP/ATP transporter 1.0879458482506026 prot_Q06497 + ADP + ATP + H+ --> ADP + ATP + H+ 0.0 -r_1112 AKG transporter, mitochonrial 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 1.1824625186845652 +r_1112 AKG transporter, mitochonrial 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 0.37954636988463575 r_1112_REV AKG transporter, mitochonrial (reversible) 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 0.0 r_1113 allantoate uniport 1.2976708311906466 prot_P15365 + allantoate --> allantoate 0.0 r_1114 allantoin uniport 10.243314336688835 prot_Q04895 + allantoin --> allantoin 0.0 -r_1115_EXP_1 ammonia transport 0.565835007774522 prot_Q12359 + ammonium --> ammonium 1.2416773605120541 +r_1115_EXP_1 ammonia transport 0.565835007774522 prot_Q12359 + ammonium --> ammonium 1.2656064633406712 r_1115_EXP_2 ammonia transport 1.0213597006592061 prot_P40260 + ammonium --> ammonium 0.0 r_1115_EXP_3 ammonia transport 1.006265993411724 prot_P41948 + ammonium --> ammonium 0.0 r_1115_EXP_4 ammonia transport 1.0117117879117519 prot_P53390 + ammonium --> ammonium 0.0 @@ -1340,7 +1340,7 @@ r_1115_REV_EXP_4 ammonia transport (reversible) 1.3558080808080808 prot_P53390 + r_1116 AMP/ATP transporter 0.6269423034333512 prot_Q06497 + AMP + ATP + H+ --> AMP + ATP + H+ 0.0 r_1118 aspartate-glutamate transporter 3.465624071522008 prot_Q12482 + L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 r_1119 biotin uptake 12.492477484389962 prot_P53241 + biotin + H+ --> biotin + H+ 0.0 -r_1120 carnithine-acetylcarnithine carrier 1.094665810308139 prot_Q12289 + (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.007861388341728892 +r_1120 carnithine-acetylcarnithine carrier 1.094665810308139 prot_Q12289 + (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.0013531064945376536 r_1121 ceramide-2' (sphinganine:n-C24:0OH) transport ceramide-2' (C24) --> ceramide-2' (C24) 0.0 r_1121_REV ceramide-2' (sphinganine:n-C24:0OH) transport (reversible) ceramide-2' (C24) --> ceramide-2' (C24) 0.0 r_1122 ceramide-2' (sphinganine:n-C26:0OH) transport ceramide-2' (C26) --> ceramide-2' (C26) 0.0 @@ -1351,12 +1351,12 @@ r_1124 ceramide-3 (Phytosphingosine:n-C26:0OH) transport ceramide-3 (C26) --> ce r_1124_REV ceramide-3 (Phytosphingosine:n-C26:0OH) transport (reversible) ceramide-3 (C26) --> ceramide-3 (C26) 0.0 r_1125 choline transport 49.19344031664132 prot_P19807 + choline + H+ --> choline + H+ 0.0 r_1126 citrate transport 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.0 -r_1126_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.38650537002419083 +r_1126_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.4125784553591591 r_1127 citrate transport 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.0 -r_1127_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.07609464734991835 +r_1127_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.033452483325451324 r_1128 citrate transport 0.3417805406736961 prot_P38152 + citrate + isocitrate --> citrate + isocitrate 0.0 r_1128_REV citrate transport (reversible) 0.3417805406736961 prot_P38152 + citrate + isocitrate --> citrate + isocitrate 0.0 -r_1129 coenzyme A transport 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.034905539507511074 +r_1129 coenzyme A transport 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.034674999369815405 r_1130 CTP transport 0.2701553629071786 prot_P38127 + CMP + CTP + H+ --> CMP + CTP + H+ 0.0 r_1131 CTP/CMP antiport 0.2701553629071786 prot_P38127 + CMP + CTP + 2.0 H+ --> CMP + CTP + 2.0 H+ 0.0008802961568487734 r_1132 cytidine transport 19.950758151174124 prot_P31381 + cytidine + H+ --> cytidine + H+ 0.0 @@ -1385,9 +1385,9 @@ r_1135_EXP_3 D-galactose transport 7.895711187219881 prot_P13181 + D-galactose + r_1135_EXP_4 D-galactose transport 9.049001302171312 prot_P42833 + D-galactose + H+ --> D-galactose + H+ 0.0 r_1135_EXP_5 D-galactose transport 0.8760873219329858 prot_P54862 + D-galactose + H+ --> D-galactose + H+ 0.0 r_1136 D-lactate transport 1398.5378967792055 prot_P36035 + (R)-lactate + H+ --> (R)-lactate + H+ 0.0 -r_1137 D-lactate transport (R)-lactate + H+ --> (R)-lactate + H+ 0.5474161206732391 +r_1137 D-lactate transport (R)-lactate + H+ --> (R)-lactate + H+ 1.9407562927841249 r_1138 D-lactate/pyruvate antiport (R)-lactate + pyruvate --> (R)-lactate + pyruvate 0.0 -r_1138_REV D-lactate/pyruvate antiport (reversible) (R)-lactate + pyruvate --> (R)-lactate + pyruvate 0.5474161206732391 +r_1138_REV D-lactate/pyruvate antiport (reversible) (R)-lactate + pyruvate --> (R)-lactate + pyruvate 1.9336439599841249 r_1139_EXP_1 D-mannose transport 21.752276959457756 prot_P54854 + D-mannose + H+ --> D-mannose + H+ 0.0 r_1139_EXP_10 D-mannose transport 5.737789186505133 prot_P40885 + D-mannose + H+ --> D-mannose + H+ 0.0 r_1139_EXP_11 D-mannose transport 24.62776935429521 prot_P47185 + D-mannose + H+ --> D-mannose + H+ 0.0 @@ -1467,12 +1467,12 @@ r_1173_EXP_3 glycine transport 12.596301854889402 prot_P38967 + H+ + L-glycine - r_1173_EXP_4 glycine transport 14.445193920799005 prot_P15380 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_EXP_5 glycine transport 7.968919773312661 prot_P53388 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_1 glycine transport (reversible) 25.955237884466197 prot_P25376 + H+ + L-glycine --> H+ + L-glycine 0.0 -r_1173_REV_EXP_2 glycine transport (reversible) 4.0449974975144505 prot_P19145 + H+ + L-glycine --> H+ + L-glycine 0.44823481080714067 +r_1173_REV_EXP_2 glycine transport (reversible) 4.0449974975144505 prot_P19145 + H+ + L-glycine --> H+ + L-glycine 0.44827168823935104 r_1173_REV_EXP_3 glycine transport (reversible) 12.596301854889402 prot_P38967 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_4 glycine transport (reversible) 14.445193920799005 prot_P15380 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_5 glycine transport (reversible) 9.41498101418254 prot_P53388 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1174 glycogen vacuolar 'transport' via autophagy glycogen --> glycogen 0.0 -r_1175 GTP/GDP translocase 0.5104257838599212 prot_P38988 + GDP + GTP + H+ --> GDP + GTP + H+ 0.04175068957202233 +r_1175 GTP/GDP translocase 0.5104257838599212 prot_P38988 + GDP + GTP + H+ --> GDP + GTP + H+ 0.041750689572022444 r_1176_EXP_1 guanine transport 1.98390967747123 prot_P17064 + guanine + H+ --> guanine + H+ 0.0 r_1176_EXP_2 guanine transport 26.93240415537185 prot_P40039 + guanine + H+ --> guanine + H+ 0.0 r_1176_EXP_3 guanine transport 75.93503728388835 prot_Q12119 + guanine + H+ --> guanine + H+ 0.0 @@ -1482,7 +1482,7 @@ r_1178_EXP_1 iron (II) transport 7.9282828282828275 prot_P40988 + iron(2+) --> i r_1178_EXP_2 iron (II) transport 9.136363636363635 prot_P38993 + iron(2+) --> iron(2+) 0.0 r_1179_EXP_1 iron (II) transport 0.8712626262626263 prot_P10566 + iron(2+) --> iron(2+) 0.0 r_1179_EXP_2 iron (II) transport 0.8410858585858586 prot_P23500 + iron(2+) --> iron(2+) 0.0 -r_1180 isoamyl acetate transport isoamyl acetate --> isoamyl acetate 0.06938276692509104 +r_1180 isoamyl acetate transport isoamyl acetate --> isoamyl acetate 0.18517216586266702 r_1181 isobutyl acetate transport isobutyl acetate --> isobutyl acetate 0.0 r_1182 isopentenyl diphosphate transport isopentenyl diphosphate --> isopentenyl diphosphate 0.0 r_1182_REV isopentenyl diphosphate transport (reversible) isopentenyl diphosphate --> isopentenyl diphosphate 0.0 @@ -1516,7 +1516,7 @@ r_1192_EXP_5 L-cystine transport 3.8637388807060162 prot_P48813 + H+ + L-cystein r_1192_EXP_6 L-cystine transport 2.0808020354818835 prot_P19145 + H+ + L-cysteine --> H+ + L-cysteine 0.0 r_1192_EXP_7 L-cystine transport 4.954940745719529 prot_P38967 + H+ + L-cysteine --> H+ + L-cysteine 0.0 r_1193 L-cystine transport 7.973877475373074 prot_P17261 + H+ + L-cystine --> H+ + L-cystine 0.0 -r_1194 L-glutamate transport 1.8810464305164725 prot_Q12482 + L-glutamate --> L-glutamate 0.33327610942807784 +r_1194 L-glutamate transport 1.8810464305164725 prot_Q12482 + L-glutamate --> L-glutamate 0.31647077161131815 r_1195 L-glutamate transport 51.467278676926874 prot_P40074 + H+ + L-glutamate --> H+ + L-glutamate 0.0 r_1196_EXP_1 L-glutamate transport 7.883394470362304 prot_P25376 + H+ + L-glutamate --> H+ + L-glutamate 0.0 r_1196_EXP_2 L-glutamate transport 92.56119945738607 prot_P43548 + H+ + L-glutamate --> H+ + L-glutamate 0.0 @@ -1626,8 +1626,8 @@ r_1229_EXP_2 NAD transport 5.294338411052739 prot_P40556 + NAD --> NAD 0.0 r_1230 NAD transport 5.294338411052739 prot_P40556 + dAMP + NAD --> dAMP + NAD 0.0 r_1231 NAD transport 2.4505467150256965 prot_P40556 + AMP + NAD --> AMP + NAD 0.0 r_1232 NAD transport 5.294338411052739 prot_P40556 + dGMP + NAD --> dGMP + NAD 0.0 -r_1235 nicotinate transport 6.441159394695592 prot_P53322 + nicotinate --> nicotinate -6.00000021222515e-08 -r_1235_REV nicotinate transport (reversible) 6.441159394695592 prot_P53322 + nicotinate --> nicotinate 6.00000021222515e-08 +r_1235 nicotinate transport 6.441159394695592 prot_P53322 + nicotinate --> nicotinate 0.0 +r_1235_REV nicotinate transport (reversible) 6.441159394695592 prot_P53322 + nicotinate --> nicotinate 0.0 r_1236 octadecanoate (n-C18:0) transport 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + stearate --> stearate 0.0 r_1236_REV octadecanoate (n-C18:0) transport (reversible) 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + stearate --> stearate 0.0 r_1237 ornithine transport 1.3730998683382918 prot_Q12375 + H+ + ornithine --> H+ + ornithine 0.031792910688328326 @@ -1637,7 +1637,7 @@ r_1241 pantothenate transport 34.938176452130854 prot_P25621 + (R)-pantothenate r_1242 pentaprenyl diphosphate transport pentaprenyl diphosphate --> pentaprenyl diphosphate 0.0 r_1242_REV pentaprenyl diphosphate transport (reversible) pentaprenyl diphosphate --> pentaprenyl diphosphate 0.0 r_1243 phenethyl acetate transport phenethyl acetate --> phenethyl acetate 0.0 -r_1244_EXP_1 phosphate transport 1.5821717171717171 prot_P38361 + H+ + phosphate --> H+ + phosphate 0.1711897450518105 +r_1244_EXP_1 phosphate transport 1.5821717171717171 prot_P38361 + H+ + phosphate --> H+ + phosphate 0.1950820904482489 r_1244_EXP_2 phosphate transport 2.5893939393939394 prot_P25360 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_3 phosphate transport 2.4668939393939393 prot_P39535 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_4 phosphate transport 1.6258080808080808 prot_P25297 + H+ + phosphate --> H+ + phosphate 0.0 @@ -1686,9 +1686,9 @@ r_1263_REV_EXP_1 spermine transport (reversible) 4.408232799564757 prot_P53283 + r_1263_REV_EXP_2 spermine transport (reversible) 14.118248201928578 prot_Q07824 + H+ + spermine --> H+ + spermine 0.0 r_1263_REV_EXP_3 spermine transport (reversible) 4.735615277275769 prot_Q12256 + H+ + spermine --> H+ + spermine 0.0 r_1263_REV_EXP_4 spermine transport (reversible) 5.6450672243090425 prot_Q06451 + H+ + spermine --> H+ + spermine 0.0 -r_1264 succinate transport 0.32879485380079526 prot_Q06143 + phosphate + succinate --> phosphate + succinate 0.0045822746107179605 +r_1264 succinate transport 0.32879485380079526 prot_Q06143 + phosphate + succinate --> phosphate + succinate 0.004809258193100673 r_1265 succinate-fumarate transport 0.5875590154537462 prot_P33303 + fumarate + succinate --> fumarate + succinate 0.03028961332473765 -r_1266_EXP_1 sulfate uniport 2.4230050505050507 prot_P38359 + sulphate --> sulphate 0.013924916568870462 +r_1266_EXP_1 sulfate uniport 2.4230050505050507 prot_P38359 + sulphate --> sulphate 0.013924916568870483 r_1266_EXP_2 sulfate uniport 2.516439393939394 prot_Q12325 + sulphate --> sulphate 0.0 r_1267 sulfite transport 296.1052693373152 prot_P41930 + sulphite --> sulphite 0.0 r_1268 taurine transport taurine --> taurine 0.0 @@ -1705,11 +1705,11 @@ r_1275 UTP transport 0.3655624733979681 prot_P38127 + FMN + H+ + UMP + UTP --> F r_1276 UTP/UMP antiport 0.3655624733979681 prot_P38127 + 2.0 H+ + UMP + UTP --> 2.0 H+ + UMP + UTP 0.0 r_1277_EXP_1 water diffusion 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_1277_EXP_2 water diffusion 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_1277_REV_EXP_1 water diffusion (reversible) 0.4050171892049932 prot_P0CD90 + H2O --> H2O 8.549752466216319 +r_1277_REV_EXP_1 water diffusion (reversible) 0.4050171892049932 prot_P0CD90 + H2O --> H2O 8.554747003252709 r_1277_REV_EXP_2 water diffusion (reversible) 0.77827345573678 prot_P0CD91 + H2O --> H2O 0.0 r_1278_EXP_1 zymosterol transport 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 0.0 r_1278_EXP_2 zymosterol transport 254.30179320863886 prot_Q08409 + zymosterol --> zymosterol 0.0 -r_1278_REV_EXP_1 zymosterol transport (reversible) 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 3.687743221822545e-05 +r_1278_REV_EXP_1 zymosterol transport (reversible) 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 0.0 r_1278_REV_EXP_2 zymosterol transport (reversible) 254.30179320863886 prot_Q08409 + zymosterol --> zymosterol 0.0 r_1449 inositol-P-ceramide B' (C24) [Golgi] SLIME rxn inositol-P-ceramide B' (C24) --> 0.910263542 inositol-P-ceramide backbone + 0.28448264 C18:0 chain + 0.36864392 C24:0 chain 0.0 r_1450 inositol-P-ceramide B' (C26) [Golgi] SLIME rxn inositol-P-ceramide B' (C26) --> 0.938317302 inositol-P-ceramide backbone + 0.28448264 C18:0 chain + 0.39669768 C26:0 chain 0.0 @@ -1725,11 +1725,11 @@ r_1479 inositol phosphomannosylinositol phosphoceramide A (C24) [Golgi] SLIME rx r_1480 inositol phosphomannosylinositol phosphoceramide A (C26) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide A (C26) --> 1.326582604 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.39669768 C26:0 chain 0.0 r_1481 inositol phosphomannosylinositol phosphoceramide B' (C24) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide B' (C24) --> 1.314528244 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.36864392 C24:0 chain 0.0 r_1482 inositol phosphomannosylinositol phosphoceramide B' (C26) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide B' (C26) --> 1.342582004 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.39669768 C26:0 chain 0.0 -r_1483 inositol phosphomannosylinositol phosphoceramide B (C24) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide B (C24) --> 1.314528244 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.36864392 C24:0 chain 0.0 +r_1483 inositol phosphomannosylinositol phosphoceramide B (C24) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide B (C24) --> 1.314528244 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.36864392 C24:0 chain -3.122369062942764e-13 r_1484 inositol phosphomannosylinositol phosphoceramide B (C26) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide B (C26) --> 1.342582004 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.39669768 C26:0 chain 0.0 r_1485 inositol phosphomannosylinositol phosphoceramide C (C24) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide C (C24) --> 1.330527644 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.36864392 C24:0 chain 0.0 r_1486 inositol phosphomannosylinositol phosphoceramide C (C26) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide C (C26) --> 1.358581404 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.39669768 C26:0 chain 0.0 -r_1487 inositol phosphomannosylinositol phosphoceramide D (C24) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide D (C24) --> 1.346527044 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.36864392 C24:0 chain 0.0 +r_1487 inositol phosphomannosylinositol phosphoceramide D (C24) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide D (C24) --> 1.346527044 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.36864392 C24:0 chain 3.0481692437735226e-13 r_1488 inositol phosphomannosylinositol phosphoceramide D (C26) [Golgi] SLIME rxn inositol phosphomannosylinositol phosphoceramide D (C26) --> 1.374580804 inositol phosphomannosylinositol phosphoceramide backbone + 0.28448264 C18:0 chain + 0.39669768 C26:0 chain 0.0 r_1509 mannosylinositol phosphorylceramide B' (C24) [Golgi] SLIME rxn mannosylinositol phosphorylceramide B' (C24) --> 1.072405942 mannosylinositol phosphorylceramide backbone + 0.28448264 C18:0 chain + 0.36864392 C24:0 chain 0.0 r_1510 mannosylinositol phosphorylceramide B' (C26) [Golgi] SLIME rxn mannosylinositol phosphorylceramide B' (C26) --> 1.100459702 mannosylinositol phosphorylceramide backbone + 0.28448264 C18:0 chain + 0.39669768 C26:0 chain 0.0 @@ -1763,9 +1763,9 @@ r_1564 2'-deoxyguanosine exchange 2'-deoxyguanosine --> 0.0 r_1565 2'-deoxyinosine exchange 2'-deoxyinosine --> 0.0 r_1566 2'-deoxyuridine exchange 2'-deoxyuridine --> 0.0 r_1567 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.0 -r_1567_REV 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport (reversible) 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.07609464734991835 +r_1567_REV 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport (reversible) 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.033452483325451324 r_1568 2-dehydropantoate transport 2-dehydropantoate --> 2-dehydropantoate 0.0 -r_1568_REV 2-dehydropantoate transport (reversible) 2-dehydropantoate --> 2-dehydropantoate 1.900000061125771e-05 +r_1568_REV 2-dehydropantoate transport (reversible) 2-dehydropantoate --> 2-dehydropantoate 1.9000000611286447e-05 r_1572 2-isopropylmalate exchange 2-isopropylmalate --> 0.0 r_1573 2-isopropylmalate transport 2-isopropylmalate --> 2-isopropylmalate 0.0 r_1573_REV 2-isopropylmalate transport (reversible) 2-isopropylmalate --> 2-isopropylmalate 0.0 @@ -1806,10 +1806,10 @@ r_1596 3-methyl-2-oxopentanoate transport (S)-3-methyl-2-oxopentanoate --> (S)-3 r_1596_REV 3-methyl-2-oxopentanoate transport (reversible) (S)-3-methyl-2-oxopentanoate --> (S)-3-methyl-2-oxopentanoate 0.0265490320174191 r_1597 3-methyl-oxopentanoate trasport (S)-3-methyl-2-oxopentanoate --> (S)-3-methyl-2-oxopentanoate 0.0 r_1597_REV 3-methyl-oxopentanoate trasport (reversible) (S)-3-methyl-2-oxopentanoate --> (S)-3-methyl-2-oxopentanoate 0.0 -r_1598 3-methylbutanal exchange 3-methylbutanal --> 0.132594736754366 -r_1599 3-methylbutanal transport 3-methylbutanal --> 3-methylbutanal 0.132594736754366 +r_1598 3-methylbutanal exchange 3-methylbutanal --> 0.0 +r_1599 3-methylbutanal transport 3-methylbutanal --> 3-methylbutanal 0.0 r_1599_REV 3-methylbutanal transport (reversible) 3-methylbutanal --> 3-methylbutanal 0.0 -r_1600 3-methylbutanal transport 3-methylbutanal --> 3-methylbutanal 0.06938276692509104 +r_1600 3-methylbutanal transport 3-methylbutanal --> 3-methylbutanal 0.18517216586266702 r_1600_REV 3-methylbutanal transport (reversible) 3-methylbutanal --> 3-methylbutanal 0.0 r_1601 3-octaprenyl-4-hydroxybenzoate transport 3-hexaprenyl-4-hydroxybenzoic acid --> 3-hexaprenyl-4-hydroxybenzoic acid 0.0 r_1601_REV 3-octaprenyl-4-hydroxybenzoate transport (reversible) 3-hexaprenyl-4-hydroxybenzoic acid --> 3-hexaprenyl-4-hydroxybenzoic acid 0.0 @@ -1817,7 +1817,7 @@ r_1603 4-amino-5-hydroxymethyl-2-methylpyrimidine synthetase 2.0579120900093906 r_1604 4-aminobenzoate exchange 4-aminobenzoate --> 0.0 r_1605 4-aminobenzoate transport 4-aminobenzoate --> 4-aminobenzoate 0.0 r_1605_REV 4-aminobenzoate transport (reversible) 4-aminobenzoate --> 4-aminobenzoate 0.0 -r_1606 4-aminobenzoate transport 4-aminobenzoate --> 4-aminobenzoate 6.340000254510467e-06 +r_1606 4-aminobenzoate transport 4-aminobenzoate --> 4-aminobenzoate 6.340000254623224e-06 r_1606_REV 4-aminobenzoate transport (reversible) 4-aminobenzoate --> 4-aminobenzoate 0.0 r_1607 4-aminobutanal transport 4-aminobutanal --> 4-aminobutanal 0.0 r_1607_REV 4-aminobutanal transport (reversible) 4-aminobutanal --> 4-aminobutanal 0.0 @@ -1844,7 +1844,7 @@ r_1620 5'-nucleotidase (XMP) 0.5934259259259259 prot_standard + H2O + xanthosine r_1621 5-aminolevulinate exchange 5-aminolevulinate --> 0.0 r_1622 5-aminolevulinate transport 5-aminolevulinate --> 5-aminolevulinate 0.0 r_1622_REV 5-aminolevulinate transport (reversible) 5-aminolevulinate --> 5-aminolevulinate 0.0 -r_1623 5-formethyltetrahydrofolate cyclo-ligase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP --> 5,10-methenyl-THF + ADP + phosphate 0.18590295261644701 +r_1623 5-formethyltetrahydrofolate cyclo-ligase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP --> 5,10-methenyl-THF + ADP + phosphate 1.0716526546341072 r_1624 5-formyltetrahydrofolate:10-formyltetrahydrofolate isomerase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP + H2O --> 10-formyl-THF + ADP + H+ + phosphate 0.0 r_1625 5-formyltetrahydrofolic acid exchange 5-formyltetrahydrofolic acid --> 0.0 r_1627 7,8-diaminononanoate exchange 7,8-diaminononanoate --> 0.0 @@ -1854,7 +1854,7 @@ r_1629 8-amino-7-oxononanoate exchange 8-amino-7-oxononanoate --> 0.0 r_1630 9H-xanthine exchange 9H-xanthine --> 0.0 r_1631 acetaldehyde exchange acetaldehyde --> 0.0 r_1632 acetaldehyde transport acetaldehyde --> acetaldehyde 0.0 -r_1632_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 2.2544970942930136 +r_1632_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.46199834052659466 r_1633 acetaldehyde transport acetaldehyde --> acetaldehyde 0.0 r_1633_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.0 r_1634 acetate exchange acetate --> 0.47703934692 @@ -1862,13 +1862,13 @@ r_1635 acetate transport acetate --> acetate 0.0 r_1635_REV acetate transport (reversible) acetate --> acetate 0.0 r_1637 acetyl-CoA transport acetyl-CoA --> acetyl-CoA 0.0 r_1637_REV acetyl-CoA transport (reversible) acetyl-CoA --> acetyl-CoA 0.0 -r_1638 acetylcarnitine transport O-acetylcarnitine --> O-acetylcarnitine 0.007861388341728892 +r_1638 acetylcarnitine transport O-acetylcarnitine --> O-acetylcarnitine 0.0013531064945376536 r_1639 adenine exchange adenine --> 0.0 r_1640 adenine transport adenine --> adenine 0.0 r_1640_REV adenine transport (reversible) adenine --> adenine 0.0 r_1641 adenosine 3',5'-bismonophosphate exchange adenosine 3',5'-bismonophosphate --> 0.0 r_1642 adenosine 3',5'-bisphosphate transport 0.12463347770546829 prot_Q12251 + adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0 -r_1642_REV adenosine 3',5'-bisphosphate transport (reversible) 0.12463347770546829 prot_Q12251 + adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.01270757217538068 +r_1642_REV adenosine 3',5'-bisphosphate transport (reversible) 0.12463347770546829 prot_Q12251 + adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.012707572175380651 r_1643 adenosine exchange adenosine --> 0.0 r_1644 ADP transport ADP --> ADP 0.0 r_1644_REV ADP transport (reversible) ADP --> ADP 0.0 @@ -1882,12 +1882,12 @@ r_1650 trehalose exchange trehalose --> 0.0 r_1651 alpha-D-glucosamine 6-phosphate exchange alpha-D-glucosamine 6-phosphate --> 0.0 r_1652 alpha-ketoglutarate/malate transporter (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 r_1652_REV alpha-ketoglutarate/malate transporter (reversible) (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 -r_1654 ammonium exchange ammonium <=> -1.2416773605120541 +r_1654 ammonium exchange ammonium <=> -1.2656064633406712 r_1656 AMP transport AMP --> AMP 0.0 r_1656_REV AMP transport (reversible) AMP --> AMP 0.0 r_1657 arginine transport 25.141189431578304 prot_P38279 + H+ + L-arginine --> H+ + L-arginine 0.0 r_1658 asparagine transport 5.8602645666708675 prot_P48813 + L-asparagine --> L-asparagine 0.0 -r_1659 aspartate-glutamate transporter L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 +r_1659 aspartate-glutamate transporter L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.00016913831181727956 r_1659_REV aspartate-glutamate transporter (reversible) L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 r_1660 ATP diffusion ATP --> ATP 0.0 r_1660_REV ATP diffusion (reversible) ATP --> ATP 0.0 @@ -1898,7 +1898,7 @@ r_1664 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + r_1664_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1665 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + H2O --> bicarbonate + H+ 0.0 r_1665_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 -r_1667 bicarbonate formation 7.346040189125295e-06 prot_P53615 + carbon dioxide + H2O --> bicarbonate + H+ 0.6885142209994399 +r_1667 bicarbonate formation 7.346040189125295e-06 prot_P53615 + carbon dioxide + H2O --> bicarbonate + H+ 0.7750048446238956 r_1667_REV bicarbonate formation (reversible) 7.346040189125295e-06 prot_P53615 + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1668 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + H2O --> bicarbonate + H+ 0.0 r_1668_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 @@ -1906,7 +1906,7 @@ r_1669 bicarbonate transport bicarbonate --> bicarbonate 0.0 r_1669_REV bicarbonate transport (reversible) bicarbonate --> bicarbonate 0.0 r_1671 biotin exchange biotin --> 0.0 r_1672 carbon dioxide exchange carbon dioxide --> 8.51059566792 -r_1673 carnitine transport (R)-carnitine --> (R)-carnitine 0.007861388341728892 +r_1673 carnitine transport (R)-carnitine --> (R)-carnitine 0.0013531064945376536 r_1674 carnitine-acetylcarnitine carrier (R)-carnitine + O-acetylcarnitine --> (R)-carnitine + O-acetylcarnitine 0.0 r_1675 CDP transport CDP --> CDP 0.0 r_1675_REV CDP transport (reversible) CDP --> CDP 0.0 @@ -1922,10 +1922,10 @@ r_1680 ceramide transport ceramide-2 (C26) --> ceramide-2 (C26) 0.0 r_1680_REV ceramide transport (reversible) ceramide-2 (C26) --> ceramide-2 (C26) 0.0 r_1681 ceramide transport ceramide-4 (C26) --> ceramide-4 (C26) 0.0 r_1681_REV ceramide transport (reversible) ceramide-4 (C26) --> ceramide-4 (C26) 0.0 -r_1682 cholestenol delta-isomerase, lumped reaction 2.489610027058053 prot_standard + oxygen + S-adenosyl-L-methionine + zymosterol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + 2.0 H2O + S-adenosyl-L-homocysteine 0.003444140750735644 +r_1682 cholestenol delta-isomerase, lumped reaction 2.489610027058053 prot_standard + oxygen + S-adenosyl-L-methionine + zymosterol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + 2.0 H2O + S-adenosyl-L-homocysteine 0.003687743244862164 r_1683 choline exchange choline --> 0.0 r_1684_EXP_1 choline transport 49.19344031664132 prot_P19807 + choline --> choline 0.0 -r_1684_EXP_2 choline transport 4.890140948879145 prot_Q12412 + choline --> choline 0.0036216614989950545 +r_1684_EXP_2 choline transport 4.890140948879145 prot_Q12412 + choline --> choline 0.0036216614996331946 r_1684_REV_EXP_1 choline transport (reversible) 49.19344031664132 prot_P19807 + choline --> choline 0.0 r_1684_REV_EXP_2 choline transport (reversible) 4.890140948879145 prot_Q12412 + choline --> choline 0.0 r_1685 chorismate pyruvate lyase 0.6162073031087573 prot_standard + chorismate --> 4-hydroxybenzoate + pyruvate 0.0 @@ -1933,28 +1933,28 @@ r_1686 citrate transport citrate --> citrate 0.0 r_1686_REV citrate transport (reversible) citrate --> citrate 0.0 r_1687 citrate exchange citrate --> 0.0 r_1688 citrate/isocitrate antiport citrate + isocitrate --> citrate + isocitrate 0.0 -r_1688_REV citrate/isocitrate antiport (reversible) citrate + isocitrate --> citrate + isocitrate 0.0 +r_1688_REV citrate/isocitrate antiport (reversible) citrate + isocitrate --> citrate + isocitrate 0.00016913831181727956 r_1689 citrate/malate antiport (S)-malate + citrate --> (S)-malate + citrate 0.0 -r_1689_REV citrate/malate antiport (reversible) (S)-malate + citrate --> (S)-malate + citrate 0.0 +r_1689_REV citrate/malate antiport (reversible) (S)-malate + citrate --> (S)-malate + citrate 0.00016913831181727956 r_1690 CMP nucleosidase 0.9660422049956934 prot_standard + CMP + H2O --> cytosine + ribose-5-phosphate 0.0 r_1691 CO2 transport carbon dioxide --> carbon dioxide 0.0 r_1691_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1694 CO2 transport carbon dioxide --> carbon dioxide 0.0 r_1694_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1695 CO2 transport carbon dioxide --> carbon dioxide 0.0 -r_1695_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 +r_1695_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.00016913831181727956 r_1696 CO2 transport carbon dioxide --> carbon dioxide 0.0 -r_1696_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 2.254609044418111 +r_1696_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 4.605597867286579 r_1697 CO2 transport carbon dioxide --> carbon dioxide 8.51059566792 r_1697_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1698 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1698_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 r_1699 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1699_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 -r_1700 coenzyme A transport coenzyme A --> coenzyme A 0.0013070928631581055 +r_1700 coenzyme A transport coenzyme A --> coenzyme A 0.0001691383118166967 r_1700_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 r_1702 cytidine exchange cytidine --> 0.0 -r_1703 cytidylate kinase (CMP) 0.015537262872628726 prot_P15700 + ATP + CMP --> ADP + CDP 0.006311982029972546 +r_1703 cytidylate kinase (CMP) 0.015537262872628726 prot_P15700 + ATP + CMP --> ADP + CDP 0.006311982030610281 r_1704 cytidylate kinase (dCMP) 0.0872640791476408 prot_P15700 + ATP + dCMP --> ADP + dCDP 0.0 r_1704_REV cytidylate kinase (dCMP) (reversible) 0.6446121633029441 prot_P15700 + ADP + dCDP --> ATP + dCMP 0.0 r_1705 cytosine exchange cytosine --> 0.0 @@ -1963,7 +1963,7 @@ r_1707_EXP_1 D-arabinose transport 12.279417568370668 prot_P39004 + D-arabinose r_1707_EXP_2 D-arabinose transport 21.95512360185767 prot_P32467 + D-arabinose --> D-arabinose 0.0 r_1707_REV_EXP_1 D-arabinose transport (reversible) 12.279417568370668 prot_P39004 + D-arabinose --> D-arabinose 0.0 r_1707_REV_EXP_2 D-arabinose transport (reversible) 21.95512360185767 prot_P32467 + D-arabinose --> D-arabinose 0.0 -r_1708 D-erythrose 4-phosphate transport D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.07609464734991835 +r_1708 D-erythrose 4-phosphate transport D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.033452483325451324 r_1708_REV D-erythrose 4-phosphate transport (reversible) D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.0 r_1709 D-fructose exchange D-fructose --> 0.0 r_1710 D-galactose exchange D-galactose --> 0.0 @@ -2005,17 +2005,17 @@ r_1732 deoxyguanosine transport 2'-deoxyguanosine --> 2'-deoxyguanosine 0.0 r_1733 deoxyinosine transport 2'-deoxyinosine --> 2'-deoxyinosine 0.0 r_1734 deoxyuridine kinase (ATP:deoxyuridine) 0.9660422049956934 prot_standard + 2'-deoxyuridine + ATP --> ADP + dUMP + H+ 0.0 r_1735 deoxyuridine transport 3.240537611534019 prot_P38196 + 2'-deoxyuridine --> 2'-deoxyuridine 0.0 -r_1736 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 0.012651693810124875 +r_1736 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 0.012642418265246421 r_1737 dGDP transport dGDP --> dGDP 0.0 r_1737_REV dGDP transport (reversible) dGDP --> dGDP 0.0 -r_1738 dhnpt transport 7,8-dihydroneopterin --> 7,8-dihydroneopterin 6.340000254510467e-06 +r_1738 dhnpt transport 7,8-dihydroneopterin --> 7,8-dihydroneopterin 6.340000254623224e-06 r_1738_REV dhnpt transport (reversible) 7,8-dihydroneopterin --> 7,8-dihydroneopterin 0.0 r_1739 diamine transaminase 1.1676441038721457 prot_Q12447 + acetyl-CoA + spermine --> coenzyme A + H+ + N(1)-acetylspermine 0.0 r_1743 dihydrofolate transport dihydrofolic acid --> dihydrofolic acid 0.0 r_1743_REV dihydrofolate transport (reversible) dihydrofolic acid --> dihydrofolic acid 0.0 r_1744 dihydroneopterin triphosphate pyrophosphatase 6.230972222222222 prot_standard + 7,8-dihydroneopterin 3'-triphosphate + H2O --> 7,8-dihydroneopterin 3'-phosphate + diphosphate + H+ 0.0 r_1745 dihydropteroate transport 7,8-dihydropteroate --> 7,8-dihydropteroate 0.0 -r_1745_REV dihydropteroate transport (reversible) 7,8-dihydropteroate --> 7,8-dihydropteroate 6.340000254510467e-06 +r_1745_REV dihydropteroate transport (reversible) 7,8-dihydropteroate --> 7,8-dihydropteroate 6.340000254623224e-06 r_1746 dihydroxyacetone phosphate transport dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_1746_REV dihydroxyacetone phosphate transport (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_1747 diphosphate transport diphosphate --> diphosphate 0.0 @@ -2041,7 +2041,7 @@ r_1761 ethanol exchange ethanol --> 2.09997852936 r_1762 ethanol transport ethanol --> ethanol 2.09997852936 r_1762_REV ethanol transport (reversible) ethanol --> ethanol 0.0 r_1763 ethanol transport, mitochondrial ethanol --> ethanol 0.0 -r_1763_REV ethanol transport, mitochondrial (reversible) ethanol --> ethanol 0.09322272635413054 +r_1763_REV ethanol transport, mitochondrial (reversible) ethanol --> ethanol 0.3487450805046808 r_1764 ethanolamine exchange ethanolamine --> 0.0 r_1765 ethyl acetate exchange ethyl acetate --> 0.0 r_1766 farnesyl diphosphate transport farnesyl diphosphate --> farnesyl diphosphate 0.0 @@ -2049,12 +2049,12 @@ r_1766_REV farnesyl diphosphate transport (reversible) farnesyl diphosphate --> r_1770 fatty acid transport 0.6366271866276696 prot_P38225 + decanoate --> decanoate 0.0 r_1770_REV fatty acid transport (reversible) 0.6366271866276696 prot_P38225 + decanoate --> decanoate 0.0 r_1771 fatty acid transport 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + laurate --> laurate 0.0 -r_1771_REV fatty acid transport (reversible) 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + laurate --> laurate 0.0005365495253866761 +r_1771_REV fatty acid transport (reversible) 28.588907052147633 prot_P34230 + 29.44222379065407 prot_P41909 + laurate --> laurate 0.0 r_1772 fatty acid transport 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + myristate --> myristate 0.0 -r_1772_REV fatty acid transport (reversible) 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + myristate --> myristate 0.0002006987647042427 +r_1772_REV fatty acid transport (reversible) 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + myristate --> myristate 0.0 r_1774 fatty acid transport 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + palmitate --> palmitate 0.0 r_1774_REV fatty acid transport (reversible) 42.90340731497117 prot_P34230 + 44.18398077425191 prot_P41909 + palmitate --> palmitate 0.0 -r_1775 fatty acid transport 0.44480530037780946 prot_P38225 + palmitoleate --> palmitoleate 0.0 +r_1775 fatty acid transport 0.44480530037780946 prot_P38225 + palmitoleate --> palmitoleate 9.275546752895991e-06 r_1775_REV fatty acid transport (reversible) 0.44480530037780946 prot_P38225 + palmitoleate --> palmitoleate 0.0 r_1776 fatty acid transport octanoate --> octanoate 0.0 r_1776_REV fatty acid transport (reversible) octanoate --> octanoate 0.0 @@ -2086,14 +2086,14 @@ r_1807 glutathione exchange glutathione --> 0.0 r_1808 glycerol exchange glycerol --> 0.11203825872 r_1809 glycerol-3-phosphate shuttle glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_1809_REV glycerol-3-phosphate shuttle (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 -r_1810 L-glycine exchange L-glycine --> 0.44823481080714067 +r_1810 L-glycine exchange L-glycine --> 0.44827168823935104 r_1811 glycine transport 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 0.0 -r_1811_REV glycine transport (reversible) 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 1.900000061125771e-05 +r_1811_REV glycine transport (reversible) 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 1.9000000611286447e-05 r_1812 glycoaldehyde transport glycolaldehyde --> glycolaldehyde 0.0 -r_1812_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 6.340000254510467e-06 +r_1812_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 6.340000254623224e-06 r_1813 glycoaldehyde transport glycolaldehyde --> glycolaldehyde 0.0 -r_1813_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 6.46000025875497e-06 -r_1814 glycolaldehyde exchange glycolaldehyde --> 6.46000025875497e-06 +r_1813_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 6.460000258867727e-06 +r_1814 glycolaldehyde exchange glycolaldehyde --> 6.460000258867727e-06 r_1815 glyoxylate exchange glyoxylate --> 0.0 r_1816 glyoxylate transport 200.53975994321283 prot_P53943 + glyoxylate --> glyoxylate 0.0 r_1816_REV glyoxylate transport (reversible) 200.53975994321283 prot_P53943 + glyoxylate --> glyoxylate 0.0 @@ -2107,19 +2107,19 @@ r_1821 guanosine kinase 0.5934259259259259 prot_standard + ATP + guanosine --> A r_1822 guanosine transport guanosine --> guanosine 0.0 r_1823 guanosine transport guanosine --> guanosine 0.0 r_1824 H+ diffusion H+ --> H+ 0.0 -r_1825 H+ diffusion H+ --> H+ 0.007412363922172949 +r_1825 H+ diffusion H+ --> H+ 0.007375486490348802 r_1825_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1826 H+ diffusion H+ --> H+ 0.0 r_1826_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1827 H+ diffusion H+ --> H+ 0.0 -r_1827_REV H+ diffusion (reversible) H+ --> H+ 0.0005472071908618926 +r_1827_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1829 H+ diffusion H+ --> H+ 0.0 r_1829_REV H+ diffusion (reversible) H+ --> H+ 0.0 -r_1830 H+ diffusion H+ --> H+ 0.0059844509054389405 +r_1830 H+ diffusion H+ --> H+ 0.00017841385857017555 r_1830_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1831 H+ diffusion H+ --> H+ 0.10083170849875056 r_1831_REV H+ diffusion (reversible) H+ --> H+ 0.0 -r_1832 H+ exchange H+ <=> 2.0948807055116063 +r_1832 H+ exchange H+ <=> 2.0468631571876017 r_1833 hexacosanoyl-CoA transport hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_1833_REV hexacosanoyl-CoA transport (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_1834 hexadecanal exchange hexadecanal --> 0.0 @@ -2133,7 +2133,7 @@ r_1838_EXP_2 homocitrate synthase 10.507993633138625 prot_P48570 + 2-oxoglutarat r_1839 hydrogen peroxide transport hydrogen peroxide --> hydrogen peroxide 0.0 r_1839_REV hydrogen peroxide transport (reversible) hydrogen peroxide --> hydrogen peroxide 0.0 r_1840 hydroxymethylglutaryl-CoA transport 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.0 -r_1840_REV hydroxymethylglutaryl-CoA transport (reversible) 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.02234772406386473 +r_1840_REV hydroxymethylglutaryl-CoA transport (reversible) 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.022126459469172983 r_1841 hypoxanthine exchange hypoxanthine --> 0.0 r_1842 hypoxanthine transport hypoxanthine --> hypoxanthine 0.0 r_1842_REV hypoxanthine transport (reversible) hypoxanthine --> hypoxanthine 0.0 @@ -2170,11 +2170,11 @@ r_1859_REV IPC transport (reversible) inositol-P-ceramide C (C26) --> inositol-P r_1860 IPC transport inositol-P-ceramide D (C26) --> inositol-P-ceramide D (C26) 0.0 r_1860_REV IPC transport (reversible) inositol-P-ceramide D (C26) --> inositol-P-ceramide D (C26) 0.0 r_1861 iron(2+) exchange iron(2+) <=> -3.0400000468944203e-06 -r_1862 isoamyl acetate exchange isoamyl acetate --> 0.06938276692509104 +r_1862 isoamyl acetate exchange isoamyl acetate --> 0.18517216586266702 r_1863 isoamyl alcohol transport isoamylol --> isoamylol 0.0 r_1863_REV isoamyl alcohol transport (reversible) isoamylol --> isoamylol 0.0 r_1864 isoamyl alcohol transport isoamylol --> isoamylol 0.0 -r_1864_REV isoamyl alcohol transport (reversible) isoamylol --> isoamylol 0.06938276692509104 +r_1864_REV isoamyl alcohol transport (reversible) isoamylol --> isoamylol 0.18517216586266702 r_1865 isoamylol exchange isoamylol --> 0.0 r_1866 isobutanol exchange isobutanol --> 0.0 r_1867 isobutyl acetate exchange isobutyl acetate --> 0.0 @@ -2276,13 +2276,13 @@ r_1919 lysine transport 22.640943053084865 prot_P38279 + L-lysine --> L-lysine 0 r_1920 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide A (C24) --> inositol phosphomannosylinositol phosphoceramide A (C24) 0.0 r_1920_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide A (C24) --> inositol phosphomannosylinositol phosphoceramide A (C24) 0.0 r_1921 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide B (C24) --> inositol phosphomannosylinositol phosphoceramide B (C24) 0.0 -r_1921_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide B (C24) --> inositol phosphomannosylinositol phosphoceramide B (C24) 0.0 +r_1921_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide B (C24) --> inositol phosphomannosylinositol phosphoceramide B (C24) -3.0481692437735226e-13 r_1922 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide B' (C24) --> inositol phosphomannosylinositol phosphoceramide B' (C24) 0.0 r_1922_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide B' (C24) --> inositol phosphomannosylinositol phosphoceramide B' (C24) 0.0 r_1923 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide C (C24) --> inositol phosphomannosylinositol phosphoceramide C (C24) 0.0 r_1923_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide C (C24) --> inositol phosphomannosylinositol phosphoceramide C (C24) 0.0 r_1924 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide D (C24) --> inositol phosphomannosylinositol phosphoceramide D (C24) 0.0 -r_1924_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide D (C24) --> inositol phosphomannosylinositol phosphoceramide D (C24) 0.0 +r_1924_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide D (C24) --> inositol phosphomannosylinositol phosphoceramide D (C24) 3.0481692437735226e-13 r_1925 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide A (C26) --> inositol phosphomannosylinositol phosphoceramide A (C26) 0.0 r_1925_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide A (C26) --> inositol phosphomannosylinositol phosphoceramide A (C26) 0.0 r_1926 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide B (C26) --> inositol phosphomannosylinositol phosphoceramide B (C26) 0.0 @@ -2293,13 +2293,13 @@ r_1928 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide C (C26 r_1928_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide C (C26) --> inositol phosphomannosylinositol phosphoceramide C (C26) 0.0 r_1929 M(IP)2C transport inositol phosphomannosylinositol phosphoceramide D (C26) --> inositol phosphomannosylinositol phosphoceramide D (C26) 0.0 r_1929_REV M(IP)2C transport (reversible) inositol phosphomannosylinositol phosphoceramide D (C26) --> inositol phosphomannosylinositol phosphoceramide D (C26) 0.0 -r_1930 malate/oxaloacetate shuttle (S)-malate + oxaloacetate --> (S)-malate + oxaloacetate 0.007291543768627552 +r_1930 malate/oxaloacetate shuttle (S)-malate + oxaloacetate --> (S)-malate + oxaloacetate 0.0010148298709036774 r_1930_REV malate/oxaloacetate shuttle (reversible) (S)-malate + oxaloacetate --> (S)-malate + oxaloacetate 0.0 r_1931 maltose exchange maltose --> 0.0 r_1932 mannan transport mannan --> mannan 0.0 r_1932_REV mannan transport (reversible) mannan --> mannan 0.070204 r_1935 methionine transport 6.982964031081571 prot_P48813 + L-methionine --> L-methionine 0.0 -r_1936 methylglyoxal synthase 1.1329040404040405 prot_standard + dihydroxyacetone phosphate --> methylglyoxal + phosphate 0.020355037763572052 +r_1936 methylglyoxal synthase 1.1329040404040405 prot_standard + dihydroxyacetone phosphate --> methylglyoxal + phosphate 0.04350234197142867 r_1937 MIPC transport mannosylinositol phosphorylceramide A (C24) --> mannosylinositol phosphorylceramide A (C24) 0.0 r_1937_REV MIPC transport (reversible) mannosylinositol phosphorylceramide A (C24) --> mannosylinositol phosphorylceramide A (C24) 0.0 r_1938 MIPC transport mannosylinositol phosphorylceramide B (C24) --> mannosylinositol phosphorylceramide B (C24) 0.0 @@ -2323,14 +2323,14 @@ r_1946_REV MIPC transport (reversible) mannosylinositol phosphorylceramide D (C2 r_1947 myo-inositol exchange myo-inositol --> 0.0 r_1952 N,N'-diformyldityrosine exchange N,N'-diformyldityrosine --> 0.0 r_1963 NADP(+) transport NADP(+) --> NADP(+) 0.0 -r_1963_REV NADP(+) transport (reversible) NADP(+) --> NADP(+) 0.007412363922172949 -r_1964 NADPH transport NADPH --> NADPH 0.007412363922172949 +r_1963_REV NADP(+) transport (reversible) NADP(+) --> NADP(+) 0.007375486490348802 +r_1964 NADPH transport NADPH --> NADPH 0.007375486490348802 r_1964_REV NADPH transport (reversible) NADPH --> NADPH 0.0 r_1965 NH3 transport ammonium --> ammonium 0.0 r_1965_REV NH3 transport (reversible) ammonium --> ammonium 0.0 r_1966 nicotinamide diffusion nicotinamide --> nicotinamide 0.0 r_1966_REV nicotinamide diffusion (reversible) nicotinamide --> nicotinamide 0.0 -r_1967 nicotinate exchange nicotinate --> 1.20000004244503e-07 +r_1967 nicotinate exchange nicotinate --> 0.0 r_1968 NMN exchange NMN --> 0.0 r_1970 NMN transport NMN --> NMN 0.0 r_1970_REV NMN transport (reversible) NMN --> NMN 0.0 @@ -2340,32 +2340,32 @@ r_1972 NMN transport NMN --> NMN 0.0 r_1974 nucleoside-diphosphatase (dGDP) 0.5934259259259259 prot_standard + dGDP + H2O --> dGMP + H+ + phosphate 0.0 r_1975 nucleoside-triphosphatase (dGTP) 0.5934259259259259 prot_standard + dGTP + H2O --> dGDP + H+ + phosphate 0.0 r_1976 O-acetylcarnintine transport into mitochondria 1.094665810308139 prot_Q12289 + O-acetylcarnitine --> O-acetylcarnitine 0.0 -r_1977 O2 transport oxygen --> oxygen 0.0037246206773107857 +r_1977 O2 transport oxygen --> oxygen 0.0036877432454866374 r_1977_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1978 O2 transport oxygen --> oxygen 5.974232371098017 +r_1978 O2 transport oxygen --> oxygen 6.070735971173749 r_1978_REV O2 transport (reversible) oxygen --> oxygen 0.0 r_1979 O2 transport oxygen --> oxygen 6.1281823300000005 r_1979_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1980 O2 transport oxygen --> oxygen 0.0067216991952838735 +r_1980 O2 transport oxygen --> oxygen 0.0005919840913751022 r_1980_REV O2 transport (reversible) oxygen --> oxygen 0.0 r_1981 octadecanoate (n-C18:0) transport 0.6366271866276696 prot_P38225 + stearate --> stearate 0.0 r_1981_REV octadecanoate (n-C18:0) transport (reversible) 0.6366271866276696 prot_P38225 + stearate --> stearate 0.0 r_1984 octanoate exchange octanoate --> 0.0 r_1987 ornithine exchange ornithine --> 0.0 -r_1988 oxaloacetate transport oxaloacetate --> oxaloacetate 6.617857303825581e-13 +r_1988 oxaloacetate transport oxaloacetate --> oxaloacetate 0.0 r_1988_REV oxaloacetate transport (reversible) oxaloacetate --> oxaloacetate 0.0 -r_1989 oxaloacetate(2-) exchange oxaloacetate --> 6.617857303825581e-13 +r_1989 oxaloacetate(2-) exchange oxaloacetate --> 0.0 r_1990 oxidized glutathione uniport 6.850627360229916 prot_P40897 + glutathione disulfide --> glutathione disulfide 0.0 r_1991 oxidized thioredoxin transport TRX1 disulphide --> TRX1 disulphide 0.0 -r_1991_REV oxidized thioredoxin transport (reversible) TRX1 disulphide --> TRX1 disulphide 0.006721699195495709 +r_1991_REV oxidized thioredoxin transport (reversible) TRX1 disulphide --> TRX1 disulphide 0.0 r_1992 oxygen exchange oxygen <-- -6.1281823300000005 r_1993 palmitate exchange palmitate --> 0.0 r_1994 palmitoleate exchange palmitoleate --> 0.0 r_1995 palmitoyl-CoA transport palmitoyl-CoA --> palmitoyl-CoA 0.0 r_1995_REV palmitoyl-CoA transport (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 r_1996 panthetheine 4'-phosphate transport pantetheine 4'-phosphate --> pantetheine 4'-phosphate 0.0 -r_1996_REV panthetheine 4'-phosphate transport (reversible) pantetheine 4'-phosphate --> pantetheine 4'-phosphate 0.012632693809513618 -r_1997 panthetheine-phosphate adenylyltransferase 3.214741247115812 prot_standard + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 7.487836586706278e-05 +r_1996_REV panthetheine 4'-phosphate transport (reversible) pantetheine 4'-phosphate --> pantetheine 4'-phosphate 0.012623418264635134 +r_1997 panthetheine-phosphate adenylyltransferase 3.214741247115812 prot_standard + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 8.415391074551606e-05 r_1998 PAP uniport adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0 r_1998_REV PAP uniport (reversible) adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0 r_1999 pectin exchange pectin --> 0.0 @@ -2376,7 +2376,7 @@ r_2002_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phen r_2003 phenylacetaldehyde transport phenylacetaldehyde --> phenylacetaldehyde 0.0 r_2003_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phenylacetaldehyde 0.0 r_2004 phenylalanine transport L-phenylalanine --> L-phenylalanine 0.0 -r_2005 phosphate exchange phosphate <=> -0.1711897450518105 +r_2005 phosphate exchange phosphate <=> -0.1950820904482489 r_2008 phosphate transport 2.5123737373737374 prot_P27514 + phosphate --> phosphate 0.0 r_2008_REV phosphate transport (reversible) 2.5123737373737374 prot_P27514 + phosphate --> phosphate 0.0 r_2020 potassium exchange potassium <=> -0.000362999993376434 @@ -2393,14 +2393,14 @@ r_2029 pyridoxine kinase 0.08096311475409836 prot_P39988 + ATP + pyridoxine --> r_2030 pyrimidine phosphatase 3.5775737902860114 prot_standard + 5-amino-6-(5-phosphoribitylamino)uracil + H2O --> 5-amino-6-(D-ribitylamino)uracil + phosphate 9.999999710998968e-05 r_2031 pyrimidine-nucleoside phosphorylase (uracil) 0.9660422049956934 prot_standard + phosphate + uridine --> alpha-D-ribose 1-phosphate(2-) + uracil 0.0 r_2031_REV pyrimidine-nucleoside phosphorylase (uracil) (reversible) 0.9660422049956934 prot_standard + alpha-D-ribose 1-phosphate(2-) + uracil --> phosphate + uridine 0.0 -r_2032 pyrophosphate transport diphosphate --> diphosphate 0.0 -r_2032_REV pyrophosphate transport (reversible) diphosphate --> diphosphate 0.04270586409473817 +r_2032 pyrophosphate transport diphosphate --> diphosphate 0.027764705830150088 +r_2032_REV pyrophosphate transport (reversible) diphosphate --> diphosphate 0.0 r_2033 pyruvate exchange pyruvate --> 0.0 r_2034_EXP_1 pyruvate transport 0.010426331697901588 prot_P53157 + 0.011285052581323294 prot_P53311 + H+ + pyruvate --> H+ + pyruvate 0.0 r_2034_EXP_2 pyruvate transport 0.011066557295101342 prot_P38857 + 0.011401101108900353 prot_P53157 + H+ + pyruvate --> H+ + pyruvate 0.0 r_2036 quinolinate transport quinolinate --> quinolinate 0.0 r_2036_REV quinolinate transport (reversible) quinolinate --> quinolinate 0.0 -r_2037 reduced thioredoxin transport TRX1 --> TRX1 0.006721699195495709 +r_2037 reduced thioredoxin transport TRX1 --> TRX1 0.0 r_2037_REV reduced thioredoxin transport (reversible) TRX1 --> TRX1 0.0 r_2038 riboflavin exchange riboflavin --> 0.0 r_2039 riboflavin transport riboflavin --> riboflavin 0.0 @@ -2411,23 +2411,23 @@ r_2042 S-adenosyl-L-homocysteine transport S-adenosyl-L-homocysteine --> S-adeno r_2042_REV S-adenosyl-L-homocysteine transport (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.0 r_2043 S-adenosyl-L-methionine exchange S-adenosyl-L-methionine --> 0.0 r_2044 S-methyl-L-methionine exchange S-methyl-L-methionine --> 0.0 -r_2045 serine transport 7.412955094957308 prot_P48813 + L-serine --> L-serine 1.900000061125771e-05 +r_2045 serine transport 7.412955094957308 prot_P48813 + L-serine --> L-serine 1.9000000611286447e-05 r_2045_REV serine transport (reversible) 7.412955094957308 prot_P48813 + L-serine --> L-serine 0.0 r_2046 sn-glycero-3-phosphocholine exchange sn-glycero-3-phosphocholine --> 0.0 r_2049 sodium exchange sodium <=> -0.0003969999961555 r_2050 spermidine acetyltransferase 0.31953703703703706 prot_standard + acetyl-CoA + spermidine --> coenzyme A + H+ + N(1)-acetylspermidine 0.0 r_2051 spermidine exchange spermidine --> 0.0 r_2052 spermine exchange spermine --> 0.0 -r_2053 squalene transport squalene --> squalene 0.0037246206773107857 +r_2053 squalene transport squalene --> squalene 0.003687743244862164 r_2053_REV squalene transport (reversible) squalene --> squalene 0.0 -r_2054 squalene-2,3-epoxide transport (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.0037246206773107857 +r_2054 squalene-2,3-epoxide transport (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.003687743244862164 r_2054_REV squalene-2,3-epoxide transport (reversible) (S)-2,3-epoxysqualene --> (S)-2,3-epoxysqualene 0.0 r_2055 stearate exchange stearate --> 0.0 r_2056 succinate exchange succinate --> 0.0 r_2057 succinate transport succinate --> succinate 0.0 r_2057_REV succinate transport (reversible) succinate --> succinate 0.0 r_2058 sucrose exchange sucrose --> 0.0 -r_2060 sulphate exchange sulphate <=> -0.013924916568870462 +r_2060 sulphate exchange sulphate <=> -0.013924916568870483 r_2061 sulphite exchange sulphite --> 0.0 r_2062 taurine exchange taurine --> 0.0 r_2063 tetracosanoyl-CoA transport tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 @@ -2461,22 +2461,22 @@ r_2090 uracil exchange uracil --> 0.0 r_2091 urea exchange urea --> 0.0 r_2092 uridine exchange uridine --> 0.0 r_2093 valine transport L-valine --> L-valine 0.0 -r_2093_REV valine transport (reversible) L-valine --> L-valine 0.2696902880514212 +r_2093_REV valine transport (reversible) L-valine --> L-valine 0.2528849502346615 r_2094_EXP_1 water diffusion 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_2094_EXP_2 water diffusion 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_2094_REV_EXP_1 water diffusion (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0037246206773107857 +r_2094_REV_EXP_1 water diffusion (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0036877432454866374 r_2094_REV_EXP_2 water diffusion (reversible) 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_2095 water diffusion H2O --> H2O 0.0 r_2095_REV water diffusion (reversible) H2O --> H2O 0.0 r_2096 water diffusion H2O --> H2O 0.0 -r_2096_REV water diffusion (reversible) H2O --> H2O 14.279063088759207 +r_2096_REV water diffusion (reversible) H2O --> H2O 15.664848847185079 r_2097 water diffusion H2O --> H2O 0.0 r_2097_REV water diffusion (reversible) H2O --> H2O 0.0 r_2098 water diffusion H2O --> H2O 0.0 -r_2098_REV water diffusion (reversible) H2O --> H2O 0.005414606332238793 +r_2098_REV water diffusion (reversible) H2O --> H2O 0.0 r_2099 water diffusion H2O --> H2O 0.0 r_2099_REV water diffusion (reversible) H2O --> H2O 0.0 -r_2100 water exchange H2O <=> 8.549752466216319 +r_2100 water exchange H2O <=> 8.554747003252709 r_2101 xanthine transport 9H-xanthine --> 9H-xanthine 0.0 r_2101_REV xanthine transport (reversible) 9H-xanthine --> 9H-xanthine 0.0 r_2102 xanthosine exchange xanthosine --> 0.0 @@ -2486,7 +2486,7 @@ r_2105_EXP_1 xylitol transport 157.39707095807333 prot_P54854 + xylitol --> xyli r_2105_EXP_2 xylitol transport 0.8243345214851523 prot_P23900 + xylitol --> xylitol 0.0 r_2105_REV_EXP_1 xylitol transport (reversible) 157.39707095807333 prot_P54854 + xylitol --> xylitol 0.0 r_2105_REV_EXP_2 xylitol transport (reversible) 0.8243345214851523 prot_P23900 + xylitol --> xylitol 0.0 -r_2106 zymosterol exchange zymosterol --> 3.687743221822545e-05 +r_2106 zymosterol exchange zymosterol --> 0.0 r_2107_EXP_1 zymosterol transport 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 0.0 r_2107_EXP_2 zymosterol transport 254.30179320863886 prot_Q08409 + zymosterol --> zymosterol 0.0 r_2107_REV_EXP_1 zymosterol transport (reversible) 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 0.0 @@ -2496,33 +2496,33 @@ r_2111 growth biomass --> 0.1 r_2112 kynurenine aminotransferase 0.06921227197346601 prot_P47039 + L-kynurenine + pyruvate --> H2O + L-alanine + kynurenic acid 0.0 r_2112_REV kynurenine aminotransferase (reversible) 0.009033549783549784 prot_P47039 + H2O + L-alanine + kynurenic acid --> L-kynurenine + pyruvate 0.0 r_2113 spontaneous kynurenic acid to quinaldic acid 0.41264716703458426 prot_standard + 2.0 H+ + NADPH + kynurenic acid --> H2O + NADP(+) + quinaldic acid 0.0 -r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.41264716703458426 prot_standard + 2-amino-3-carboxymuconate-6-semialdehyde --> H+ + H2O + quinolinate 0.0006071199974008957 +r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.41264716703458426 prot_standard + 2-amino-3-carboxymuconate-6-semialdehyde --> H+ + H2O + quinolinate 0.0006069999973934842 r_2115_EXP_1 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.03339649287148808 prot_P38113 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.0 -r_2115_EXP_2 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.011373148148148148 prot_P00330 + acetaldehyde + H+ + NADH --> ethanol + NAD 2.0067558030058694 +r_2115_EXP_2 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.011373148148148148 prot_P00330 + acetaldehyde + H+ + NADH --> ethanol + NAD 1.7512334488553192 r_2116_EXP_1 acetaldehyde dehydrogenase 0.06942013888888889 prot_Q04458 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_2 acetaldehyde dehydrogenase 0.483596214511041 prot_P47771 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_3 acetaldehyde dehydrogenase 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_4 acetaldehyde dehydrogenase 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 -r_2117 phenylalanine transaminase 0.05744797801334904 prot_P38840 + L-phenylalanine + pyruvate --> keto-phenylpyruvate + L-alanine 0.046424589344309306 +r_2117 phenylalanine transaminase 0.05744797801334904 prot_P38840 + L-phenylalanine + pyruvate --> keto-phenylpyruvate + L-alanine 0.04642458934430109 r_2117_REV phenylalanine transaminase (reversible) 0.010556998556998556 prot_P38840 + keto-phenylpyruvate + L-alanine --> L-phenylalanine + pyruvate 0.0 r_2118 tryptophan transaminase 0.05744797801334904 prot_P38840 + keto-phenylpyruvate + L-tryptophan --> indole-3-pyruvate + L-phenylalanine 0.0 r_2119 tyrosine transaminase 0.010556998556998556 prot_P38840 + 3-(4-hydroxyphenyl)pyruvate + L-alanine --> L-tyrosine + pyruvate 0.012302566079285501 r_2119_REV tyrosine transaminase (reversible) 0.11696243005595523 prot_P38840 + L-tyrosine + pyruvate --> 3-(4-hydroxyphenyl)pyruvate + L-alanine 0.0 r_2125 coenzyme A: cytoplasm to LP coenzyme A --> coenzyme A 0.0 -r_2125_REV coenzyme A: cytoplasm to LP (reversible) coenzyme A --> coenzyme A 1.879008018239466e-05 +r_2125_REV coenzyme A: cytoplasm to LP (reversible) coenzyme A --> coenzyme A 0.0011486997754021106 r_2126 sedoheptulose bisphosphatase 2.051719576719577 prot_P36136 + H2O + sedoheptulose 1,7-bisphosphate --> phosphate + sedoheptulose 7-phosphate 0.0 r_2129 proton leak H+ --> H+ 0.0 -r_2131 isocitrate dehydrogenase 0.47807539682539685 prot_P21954 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.0 +r_2131 isocitrate dehydrogenase 0.47807539682539685 prot_P21954 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.19799263291720112 r_2132_EXP_1 oxoglutarate/malate exchange 0.3902368014935992 prot_Q99297 + (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 r_2132_EXP_2 oxoglutarate/malate exchange 2.6118993789038507 prot_Q03028 + (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 r_2134 14-demethyllanosterol exchange 14-demethyllanosterol --> 0.0 r_2136 14-demethyllanosterol transport 14-demethyllanosterol --> 14-demethyllanosterol 0.0 r_2136_REV 14-demethyllanosterol transport (reversible) 14-demethyllanosterol --> 14-demethyllanosterol 0.0 -r_2137 ergosta-5,7,22,24(28)-tetraen-3beta-ol exchange ergosta-5,7,22,24(28)-tetraen-3beta-ol --> 2.3039643110012165e-13 +r_2137 ergosta-5,7,22,24(28)-tetraen-3beta-ol exchange ergosta-5,7,22,24(28)-tetraen-3beta-ol --> 0.0 r_2139 ergosta-5,7,22,24(28)-tetraen-3beta-ol transport ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 -r_2139_REV ergosta-5,7,22,24(28)-tetraen-3beta-ol transport (reversible) ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 2.3039643110012165e-13 -r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 27.714912457481013 prot_P07149 + 25.079771343596047 prot_P19097 + acetyl-CoA + 21.0 H+ + 7.0 malonyl-CoA + 14.0 NADPH --> 7.0 carbon dioxide + 7.0 coenzyme A + 7.0 H2O + 14.0 NADP(+) + palmitoyl-CoA 0.012313280748221392 -r_2141 fatty-acyl-CoA synthase (n-C18:0CoA) 50.82022222222222 prot_P07149 + 45.98822222222222 prot_P19097 + acetyl-CoA + 24.0 H+ + 8.0 malonyl-CoA + 16.0 NADPH --> 8.0 carbon dioxide + 8.0 coenzyme A + 8.0 H2O + 16.0 NADP(+) + stearoyl-CoA 0.004616251668739916 +r_2139_REV ergosta-5,7,22,24(28)-tetraen-3beta-ol transport (reversible) ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 +r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 27.714912457481013 prot_P07149 + 25.079771343596047 prot_P19097 + acetyl-CoA + 21.0 H+ + 7.0 malonyl-CoA + 14.0 NADPH --> 7.0 carbon dioxide + 7.0 coenzyme A + 7.0 H2O + 14.0 NADP(+) + palmitoyl-CoA 0.01652882615567189 +r_2141 fatty-acyl-CoA synthase (n-C18:0CoA) 50.82022222222222 prot_P07149 + 45.98822222222222 prot_P19097 + acetyl-CoA + 24.0 H+ + 8.0 malonyl-CoA + 16.0 NADPH --> 8.0 carbon dioxide + 8.0 coenzyme A + 8.0 H2O + 16.0 NADP(+) + stearoyl-CoA 0.0 r_2142 B-ketoacyl-ACP synthase (acetoacetyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + acetyl-ACP + carboxyacetyl-ACP --> carbon dioxide + ACP1 + acetoacetyl-ACP 0.0 r_2143 B-ketoacyl-ACP synthase (3-oxo-hexanoyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + carboxyacetyl-ACP + butanoyl-ACP --> carbon dioxide + ACP1 + 3-oxo-hexanoyl-ACP 0.0 r_2144 B-ketoacyl-ACP synthase (3-oxo-octanoyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + carboxyacetyl-ACP + hexanoyl-ACP --> carbon dioxide + ACP1 + 3-oxo-octanoyl-ACP 0.0 @@ -2538,45 +2538,45 @@ r_2150_REV 3-hydroxyacyl-thioester dehydratase (trans-oct-2-enoyl-ACP) (reversib r_2151 enoyl-ACP reductase (butanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NADPH + trans-but-2-enoyl-ACP --> NADP(+) + butanoyl-ACP 0.0 r_2152 enoyl-ACP reductase (hexanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NADPH + trans-hex-2-enoyl-ACP --> NADP(+) + hexanoyl-ACP 0.0 r_2153 enoyl-ACP reductase (octanoyl-ACP) 422.766923942756 prot_P38071 + H+ + NADPH + trans-oct-2-enoyl-ACP --> NADP(+) + octanoyl-ACP 0.0 -r_2154 elongase I (3-oxotetradecanoyl-CoA) 0.36517429674617 prot_P39540 + lauroyl-CoA + malonyl-CoA + H+ --> carbon dioxide + coenzyme A + 3-oxotetradecanoyl-CoA 0.0005365495253866761 -r_2155 elongase I (3-oxopalmitoyl-CoA) 0.36517429674617 prot_P39540 + malonyl-CoA + H+ + myristoyl-CoA --> carbon dioxide + coenzyme A + 3-oxopalmitoyl-CoA 0.0007372482900909188 -r_2156 elongase II (3-oxooctadecanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + palmitoyl-CoA --> carbon dioxide + coenzyme A + 3-oxooctadecanoyl-CoA 0.0 +r_2154 elongase I (3-oxotetradecanoyl-CoA) 0.36517429674617 prot_P39540 + lauroyl-CoA + malonyl-CoA + H+ --> carbon dioxide + coenzyme A + 3-oxotetradecanoyl-CoA 0.0 +r_2155 elongase I (3-oxopalmitoyl-CoA) 0.36517429674617 prot_P39540 + malonyl-CoA + H+ + myristoyl-CoA --> carbon dioxide + coenzyme A + 3-oxopalmitoyl-CoA 0.0 +r_2156 elongase II (3-oxooctadecanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + palmitoyl-CoA --> carbon dioxide + coenzyme A + 3-oxooctadecanoyl-CoA 0.003879003378584339 r_2157_EXP_1 elongase II or III (3-oxoicosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + stearoyl-CoA --> carbon dioxide + coenzyme A + 3-oxoicosanoyl-CoA 0.0 -r_2157_EXP_2 elongase II or III (3-oxoicosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + stearoyl-CoA --> carbon dioxide + coenzyme A + 3-oxoicosanoyl-CoA 0.00032289641279162194 +r_2157_EXP_2 elongase II or III (3-oxoicosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + stearoyl-CoA --> carbon dioxide + coenzyme A + 3-oxoicosanoyl-CoA 0.0 r_2158_EXP_1 elongase II or III (3-oxodocosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + icosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxodocosanoyl-CoA 0.0 -r_2158_EXP_2 elongase II or III (3-oxodocosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + icosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxodocosanoyl-CoA 0.00032289641279162194 +r_2158_EXP_2 elongase II or III (3-oxodocosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + icosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxodocosanoyl-CoA 0.0 r_2159_EXP_1 elongase II or III (3-oxotetracosanoyl-CoA) 1.8455931395379834 prot_P25358 + malonyl-CoA + H+ + docosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxotetracosanoyl-CoA 0.0 -r_2159_EXP_2 elongase II or III (3-oxotetracosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + docosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxotetracosanoyl-CoA 0.00032289641279162194 -r_2160 elongase III (3-oxohexacosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + tetracosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxohexacosanoyl-CoA 0.00032289641279162194 -r_2161 B-ketoacyl-CoA reductase ((S)-3-hydroxytetradecanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxotetradecanoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxytetradecanoyl-CoA 0.0005365495253866761 -r_2162 B-ketoacyl-CoA reductase ((S)-3-hydroxypalmitoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxopalmitoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxypalmitoyl-CoA 0.0007372482900909188 -r_2163 B-ketoacyl-CoA reductase (3-hydroxyoctadecanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxooctadecanoyl-CoA + NADPH --> NADP(+) + 3-hydroxyoctadecanoyl-CoA 0.0 -r_2164 B-ketoacyl-CoA reductase (3-hydroxyicosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxoicosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxyicosanoyl-CoA 0.00032289641279162194 -r_2165 B-ketoacyl-CoA reductase (3-hydroxydocosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxodocosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxydocosanoyl-CoA 0.00032289641279162194 -r_2166 B-ketoacyl-CoA reductase (3-hydroxytetracosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxotetracosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxytetracosanoyl-CoA 0.00032289641279162194 -r_2167 B-ketoacyl-CoA reductase ((S)-3-hydroxyhexacosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxohexacosanoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxyhexacosanoyl-CoA 0.00032289641279162194 -r_2168 B-hydroxyacyl-CoA dehydratase (trans-tetradec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxytetradecanoyl-CoA --> H2O + trans-tetradec-2-enoyl-CoA 0.0005365495253866761 +r_2159_EXP_2 elongase II or III (3-oxotetracosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + docosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxotetracosanoyl-CoA 0.0 +r_2160 elongase III (3-oxohexacosanoyl-CoA) 0.49218897590613386 prot_P40319 + malonyl-CoA + H+ + tetracosanoyl-CoA --> carbon dioxide + coenzyme A + 3-oxohexacosanoyl-CoA 0.0 +r_2161 B-ketoacyl-CoA reductase ((S)-3-hydroxytetradecanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxotetradecanoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxytetradecanoyl-CoA 0.0 +r_2162 B-ketoacyl-CoA reductase ((S)-3-hydroxypalmitoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxopalmitoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxypalmitoyl-CoA 0.0 +r_2163 B-ketoacyl-CoA reductase (3-hydroxyoctadecanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxooctadecanoyl-CoA + NADPH --> NADP(+) + 3-hydroxyoctadecanoyl-CoA 0.003879003378584339 +r_2164 B-ketoacyl-CoA reductase (3-hydroxyicosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxoicosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxyicosanoyl-CoA 0.0 +r_2165 B-ketoacyl-CoA reductase (3-hydroxydocosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxodocosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxydocosanoyl-CoA 0.0 +r_2166 B-ketoacyl-CoA reductase (3-hydroxytetracosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxotetracosanoyl-CoA + NADPH --> NADP(+) + 3-hydroxytetracosanoyl-CoA 0.0 +r_2167 B-ketoacyl-CoA reductase ((S)-3-hydroxyhexacosanoyl-CoA) 7.688053878671216 prot_P38286 + H+ + 3-oxohexacosanoyl-CoA + NADPH --> NADP(+) + (S)-3-hydroxyhexacosanoyl-CoA 0.0 +r_2168 B-hydroxyacyl-CoA dehydratase (trans-tetradec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxytetradecanoyl-CoA --> H2O + trans-tetradec-2-enoyl-CoA 0.0 r_2168_REV B-hydroxyacyl-CoA dehydratase (trans-tetradec-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-tetradec-2-enoyl-CoA --> (S)-3-hydroxytetradecanoyl-CoA 0.0 -r_2169 B-hydroxyacyl-CoA dehydratase (trans-hexadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxypalmitoyl-CoA --> H2O + trans-hexadec-2-enoyl-CoA 0.0007372482900909188 +r_2169 B-hydroxyacyl-CoA dehydratase (trans-hexadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxypalmitoyl-CoA --> H2O + trans-hexadec-2-enoyl-CoA 0.0 r_2169_REV B-hydroxyacyl-CoA dehydratase (trans-hexadec-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-hexadec-2-enoyl-CoA --> (S)-3-hydroxypalmitoyl-CoA 0.0 -r_2170 B-hydroxyacyl-CoA dehydratase (trans-octadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxyoctadecanoyl-CoA --> H2O + trans-octadec-2-enoyl-CoA 0.0 +r_2170 B-hydroxyacyl-CoA dehydratase (trans-octadec-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxyoctadecanoyl-CoA --> H2O + trans-octadec-2-enoyl-CoA 0.003879003378584339 r_2170_REV B-hydroxyacyl-CoA dehydratase (trans-octadec-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-octadec-2-enoyl-CoA --> 3-hydroxyoctadecanoyl-CoA 0.0 -r_2171 B-hydroxyacyl-CoA dehydratase (trans-icos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxyicosanoyl-CoA --> H2O + trans-icos-2-enoyl-CoA 0.00032289641279162194 +r_2171 B-hydroxyacyl-CoA dehydratase (trans-icos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxyicosanoyl-CoA --> H2O + trans-icos-2-enoyl-CoA 0.0 r_2171_REV B-hydroxyacyl-CoA dehydratase (trans-icos-2-enoyl-CoA) (reversible) 7.243203309692672e-06 prot_P40857 + H2O + trans-icos-2-enoyl-CoA --> 3-hydroxyicosanoyl-CoA 0.0 -r_2172 B-hydroxyacyl-CoA dehydratase (trans-docos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxydocosanoyl-CoA --> H2O + trans-docos-2-enoyl-CoA 0.00032289641279162194 +r_2172 B-hydroxyacyl-CoA dehydratase (trans-docos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxydocosanoyl-CoA --> H2O + trans-docos-2-enoyl-CoA 0.0 r_2172_REV B-hydroxyacyl-CoA dehydratase (trans-docos-2-enoyl-CoA) (reversible) 1.0640387527540613 prot_P40857 + H2O + trans-docos-2-enoyl-CoA --> 3-hydroxydocosanoyl-CoA 0.0 -r_2173 B-hydroxyacyl-CoA dehydratase (trans-tetracos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxytetracosanoyl-CoA --> H2O + trans-tetracos-2-enoyl-CoA 0.00032289641279162194 -r_2174 B-hydroxyacyl-CoA dehydratase (trans-hexacos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxyhexacosanoyl-CoA --> H2O + trans-hexacos-2-enoyl-CoA 0.00032289641279162194 +r_2173 B-hydroxyacyl-CoA dehydratase (trans-tetracos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + 3-hydroxytetracosanoyl-CoA --> H2O + trans-tetracos-2-enoyl-CoA 0.0 +r_2174 B-hydroxyacyl-CoA dehydratase (trans-hexacos-2-enoyl-CoA) 0.909635672543336 prot_P40857 + (S)-3-hydroxyhexacosanoyl-CoA --> H2O + trans-hexacos-2-enoyl-CoA 0.0 r_2174_REV B-hydroxyacyl-CoA dehydratase (trans-hexacos-2-enoyl-CoA) (reversible) 1.0013787340051172 prot_P40857 + H2O + trans-hexacos-2-enoyl-CoA --> (S)-3-hydroxyhexacosanoyl-CoA 0.0 -r_2175 trans-2-enoyl-CoA reductase (n-C14:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-tetradec-2-enoyl-CoA --> myristoyl-CoA + NADP(+) 0.0005365495253866761 -r_2176 trans-2-enoyl-CoA reductase (n-C16:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexadec-2-enoyl-CoA --> palmitoyl-CoA + NADP(+) 0.0007372482900909188 -r_2177 trans-2-enoyl-CoA reductase (n-C18:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-octadec-2-enoyl-CoA --> stearoyl-CoA + NADP(+) 0.0 -r_2178 trans-2-enoyl-CoA reductase (n-C20:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-icos-2-enoyl-CoA --> icosanoyl-CoA + NADP(+) 0.00032289641279162194 -r_2179 trans-2-enoyl-CoA reductase (n-C22:0CoA) 3.5110799393544463 prot_Q99190 + H+ + NADPH + trans-docos-2-enoyl-CoA --> docosanoyl-CoA + NADP(+) 0.00032289641279162194 -r_2180 trans-2-enoyl-CoA reductase (n-C24:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-tetracos-2-enoyl-CoA --> tetracosanoyl-CoA + NADP(+) 0.00032289641279162194 -r_2181 trans-2-enoyl-CoA reductase (n-C26:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexacos-2-enoyl-CoA --> NADP(+) + hexacosanoyl-CoA 0.00032289641279162194 -r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 13.846040131031963 prot_P21147 + H+ + palmitoyl-CoA + oxygen + NADH --> 2.0 H2O + palmitoleoyl-CoA(4-) + NAD 0.009897280316299916 -r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 46.3515873015873 prot_P21147 + H+ + stearoyl-CoA + oxygen + NADH --> 2.0 H2O + NAD + oleoyl-CoA 0.0030823586426598952 +r_2175 trans-2-enoyl-CoA reductase (n-C14:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-tetradec-2-enoyl-CoA --> myristoyl-CoA + NADP(+) 0.0 +r_2176 trans-2-enoyl-CoA reductase (n-C16:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexadec-2-enoyl-CoA --> palmitoyl-CoA + NADP(+) 0.0 +r_2177 trans-2-enoyl-CoA reductase (n-C18:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-octadec-2-enoyl-CoA --> stearoyl-CoA + NADP(+) 0.003879003378584339 +r_2178 trans-2-enoyl-CoA reductase (n-C20:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-icos-2-enoyl-CoA --> icosanoyl-CoA + NADP(+) 0.0 +r_2179 trans-2-enoyl-CoA reductase (n-C22:0CoA) 3.5110799393544463 prot_Q99190 + H+ + NADPH + trans-docos-2-enoyl-CoA --> docosanoyl-CoA + NADP(+) 0.0 +r_2180 trans-2-enoyl-CoA reductase (n-C24:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-tetracos-2-enoyl-CoA --> tetracosanoyl-CoA + NADP(+) 0.0 +r_2181 trans-2-enoyl-CoA reductase (n-C26:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexacos-2-enoyl-CoA --> NADP(+) + hexacosanoyl-CoA 0.0 +r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 13.846040131031963 prot_P21147 + H+ + palmitoyl-CoA + oxygen + NADH --> 2.0 H2O + palmitoleoyl-CoA(4-) + NAD 0.009496574054985385 +r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 46.3515873015873 prot_P21147 + H+ + stearoyl-CoA + oxygen + NADH --> 2.0 H2O + NAD + oleoyl-CoA 0.0030823586426598944 r_2184 octanoate (n-C8:0) transport octanoate --> octanoate 0.0 r_2184_REV octanoate (n-C8:0) transport (reversible) octanoate --> octanoate 0.0 r_2185 decanoate (n-C10:0) transport decanoate --> decanoate 0.0 @@ -2595,7 +2595,7 @@ r_2192_REV octadecenoate (n-C18:1) transport (reversible) 1.1688088711408016 pro r_2193 myristate exchange myristate --> 0.0 r_2194 fatty-acid--CoA ligase (dodecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + laurate --> lauroyl-CoA + AMP + diphosphate 0.0 r_2194_REV fatty-acid--CoA ligase (dodecanoate), ER membrane (reversible) 4.27578504719294 prot_P30624 + lauroyl-CoA + AMP + diphosphate --> coenzyme A + ATP + laurate 0.0 -r_2195_EXP_1 fatty-acid--CoA ligase (tetradecanoate), ER membrane 740.1053639846743 prot_P47912 + coenzyme A + ATP + myristate --> myristoyl-CoA + AMP + diphosphate 0.0002006987647042427 +r_2195_EXP_1 fatty-acid--CoA ligase (tetradecanoate), ER membrane 740.1053639846743 prot_P47912 + coenzyme A + ATP + myristate --> myristoyl-CoA + AMP + diphosphate 0.0 r_2195_EXP_2 fatty-acid--CoA ligase (tetradecanoate), ER membrane 745.8429118773946 prot_P30624 + coenzyme A + ATP + myristate --> myristoyl-CoA + AMP + diphosphate 0.0 r_2195_REV_EXP_1 fatty-acid--CoA ligase (tetradecanoate), ER membrane (reversible) 3.0403097470779796 prot_P47912 + myristoyl-CoA + AMP + diphosphate --> coenzyme A + ATP + myristate 0.0 r_2195_REV_EXP_2 fatty-acid--CoA ligase (tetradecanoate), ER membrane (reversible) 4.27578504719294 prot_P30624 + myristoyl-CoA + AMP + diphosphate --> coenzyme A + ATP + myristate 0.0 @@ -2615,7 +2615,7 @@ r_2199_EXP_1 fatty-acid--CoA ligase (octadecenoate), ER membrane 646.43697171813 r_2199_EXP_2 fatty-acid--CoA ligase (octadecenoate), ER membrane 651.4483704531559 prot_P30624 + coenzyme A + ATP + oleate --> oleoyl-CoA + AMP + diphosphate 0.0 r_2199_REV_EXP_1 fatty-acid--CoA ligase (octadecenoate), ER membrane (reversible) 3.15048984865542 prot_P47912 + oleoyl-CoA + AMP + diphosphate --> coenzyme A + ATP + oleate 0.0 r_2199_REV_EXP_2 fatty-acid--CoA ligase (octadecenoate), ER membrane (reversible) 4.477103447320649 prot_P30624 + oleoyl-CoA + AMP + diphosphate --> coenzyme A + ATP + oleate 0.0 -r_2200 fatty-acid--CoA ligase (dodecanoate), lipid particle 745.8429118773946 prot_P30624 + coenzyme A + ATP + laurate --> diphosphate + AMP + lauroyl-CoA 0.000536549525386676 +r_2200 fatty-acid--CoA ligase (dodecanoate), lipid particle 745.8429118773946 prot_P30624 + coenzyme A + ATP + laurate --> diphosphate + AMP + lauroyl-CoA 0.0 r_2200_REV fatty-acid--CoA ligase (dodecanoate), lipid particle (reversible) 4.27578504719294 prot_P30624 + diphosphate + AMP + lauroyl-CoA --> coenzyme A + ATP + laurate 0.0 r_2201_EXP_1 fatty-acid--CoA ligase (tetradecanoate), lipid particle 740.1053639846743 prot_P47912 + coenzyme A + ATP + myristate --> diphosphate + AMP + myristoyl-CoA 0.0 r_2201_EXP_2 fatty-acid--CoA ligase (tetradecanoate), lipid particle 745.8429118773946 prot_P30624 + coenzyme A + ATP + myristate --> diphosphate + AMP + myristoyl-CoA 0.0 @@ -2627,7 +2627,7 @@ r_2202_REV_EXP_1 fatty-acid--CoA ligase (hexadecanoate), lipid particle (reversi r_2202_REV_EXP_2 fatty-acid--CoA ligase (hexadecanoate), lipid particle (reversible) 4.27578504719294 prot_P30624 + diphosphate + AMP + palmitoyl-CoA --> coenzyme A + ATP + palmitate 0.0 r_2203_EXP_1 fatty-acid--CoA ligase (hexadecenoate), lipid particle 376.2385922203972 prot_P47912 + coenzyme A + ATP + palmitoleate --> diphosphate + AMP + palmitoleoyl-CoA(4-) 0.0 r_2203_EXP_2 fatty-acid--CoA ligase (hexadecenoate), lipid particle 379.1553214416692 prot_P30624 + coenzyme A + ATP + palmitoleate --> diphosphate + AMP + palmitoleoyl-CoA(4-) 0.0 -r_2203_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), lipid particle (reversible) 3.189962202455639 prot_P47912 + diphosphate + AMP + palmitoleoyl-CoA(4-) --> coenzyme A + ATP + palmitoleate 0.0 +r_2203_REV_EXP_1 fatty-acid--CoA ligase (hexadecenoate), lipid particle (reversible) 3.189962202455639 prot_P47912 + diphosphate + AMP + palmitoleoyl-CoA(4-) --> coenzyme A + ATP + palmitoleate 0.0005933601698330152 r_2203_REV_EXP_2 fatty-acid--CoA ligase (hexadecenoate), lipid particle (reversible) 4.583272040765874 prot_P30624 + diphosphate + AMP + palmitoleoyl-CoA(4-) --> coenzyme A + ATP + palmitoleate 0.0 r_2204_EXP_1 fatty-acid--CoA ligase (octadecanoate), lipid particle 740.1053639846743 prot_P47912 + coenzyme A + ATP + stearate --> diphosphate + AMP + stearoyl-CoA 0.0 r_2204_EXP_2 fatty-acid--CoA ligase (octadecanoate), lipid particle 745.8429118773946 prot_P30624 + coenzyme A + ATP + stearate --> diphosphate + AMP + stearoyl-CoA 0.0 @@ -2637,7 +2637,7 @@ r_2205_EXP_1 fatty-acid--CoA ligase (octadecenoate), lipid particle 1069.9820995 r_2205_EXP_2 fatty-acid--CoA ligase (octadecenoate), lipid particle 1078.2769637722536 prot_P30624 + coenzyme A + ATP + oleate --> diphosphate + AMP + oleoyl-CoA 0.0 r_2205_REV_EXP_1 fatty-acid--CoA ligase (octadecenoate), lipid particle (reversible) 3.15048984865542 prot_P47912 + diphosphate + AMP + oleoyl-CoA --> coenzyme A + ATP + oleate 0.0 r_2205_REV_EXP_2 fatty-acid--CoA ligase (octadecenoate), lipid particle (reversible) 4.477103447320649 prot_P30624 + diphosphate + AMP + oleoyl-CoA --> coenzyme A + ATP + oleate 0.0 -r_2206 fatty-acid--CoA ligase (hexadecenoate), peroxisome 799.2145593869732 prot_P39518 + ATP + coenzyme A + palmitoleate --> AMP + diphosphate + palmitoleoyl-CoA(4-) 0.0 +r_2206 fatty-acid--CoA ligase (hexadecenoate), peroxisome 799.2145593869732 prot_P39518 + ATP + coenzyme A + palmitoleate --> AMP + diphosphate + palmitoleoyl-CoA(4-) 9.275546752895991e-06 r_2206_REV fatty-acid--CoA ligase (hexadecenoate), peroxisome (reversible) 35.32799384939581 prot_P39518 + AMP + diphosphate + palmitoleoyl-CoA(4-) --> ATP + coenzyme A + palmitoleate 0.0 r_2207 fatty-acid--CoA ligase (octadecanoate), peroxisome 799.2145593869732 prot_P39518 + ATP + coenzyme A + stearate --> AMP + diphosphate + stearoyl-CoA 0.0 r_2207_REV fatty-acid--CoA ligase (octadecanoate), peroxisome (reversible) 33.739859453840296 prot_P39518 + AMP + diphosphate + stearoyl-CoA --> ATP + coenzyme A + stearate 0.0 @@ -2666,13 +2666,13 @@ r_2218_REV fatty-acid--CoA ligase (cerotic acid), lipid particle (reversible) 1. r_2219 fatty acyl-CoA transport via ABC system (C12:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + lauroyl-CoA --> ADP + H+ + lauroyl-CoA + phosphate 0.0 r_2220 fatty acyl-CoA transport via ABC system (C14:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + myristoyl-CoA --> ADP + H+ + myristoyl-CoA + phosphate 0.0 r_2221 fatty acyl-CoA transport via ABC system (C16:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + palmitoyl-CoA --> ADP + H+ + palmitoyl-CoA + phosphate 0.0 -r_2222 fatty acyl-CoA transport via ABC system (C16:1) 102.59519988879609 prot_P34230 + 105.65744361835995 prot_P41909 + ATP + H2O + palmitoleoyl-CoA(4-) --> ADP + H+ + phosphate + palmitoleoyl-CoA(4-) 0.0005698445731318472 -r_2223 fatty acyl-CoA transport via ABC system (C18:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + stearoyl-CoA --> ADP + H+ + phosphate + stearoyl-CoA 0.00041435187737137513 +r_2222 fatty acyl-CoA transport via ABC system (C16:1) 102.59519988879609 prot_P34230 + 105.65744361835995 prot_P41909 + ATP + H2O + palmitoleoyl-CoA(4-) --> ADP + H+ + phosphate + palmitoleoyl-CoA(4-) 0.00015986276506438357 +r_2223 fatty acyl-CoA transport via ABC system (C18:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + stearoyl-CoA --> ADP + H+ + phosphate + stearoyl-CoA 0.0 r_2224 fatty acyl-CoA transport via ABC system (C18:1) 102.6162244595619 prot_P34230 + 105.67909572686696 prot_P41909 + ATP + H2O + oleoyl-CoA --> ADP + H+ + oleoyl-CoA + phosphate 0.0 r_2225 fatty acyl-CoA transport via ABC system (C20:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + icosanoyl-CoA --> ADP + H+ + phosphate + icosanoyl-CoA 0.0 r_2226 fatty acyl-CoA transport via ABC system (C22:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + docosanoyl-CoA --> ADP + H+ + phosphate + docosanoyl-CoA 0.0 r_2227 fatty acyl-CoA transport via ABC system (C24:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + tetracosanoyl-CoA --> ADP + H+ + phosphate + tetracosanoyl-CoA 0.0 -r_2228 fatty acyl-CoA transport via ABC system (C26:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + hexacosanoyl-CoA --> ADP + H+ + hexacosanoyl-CoA + phosphate 0.00032289641279162194 +r_2228 fatty acyl-CoA transport via ABC system (C26:0) 98.11631465013791 prot_P34230 + 101.04487339002989 prot_P41909 + ATP + H2O + hexacosanoyl-CoA --> ADP + H+ + hexacosanoyl-CoA + phosphate 0.0 r_2229 butyrate (n-C4:0) transport, cytoplasm-peroxisome butyrate --> butyrate 0.0 r_2229_REV butyrate (n-C4:0) transport, cytoplasm-peroxisome (reversible) butyrate --> butyrate 0.0 r_2230 hexanoate (n-C6:0) transport, cytoplasm-peroxisome hexanoate --> hexanoate 0.0 @@ -2683,80 +2683,80 @@ r_2232 peroxisomal acyl-CoA thioesterase (4:0) 0.12566955088586731 prot_P41903 + r_2233 peroxisomal acyl-CoA thioesterase (6:0) 931.9444444444443 prot_P41903 + H2O + hexanoyl-CoA --> coenzyme A + 5.0 H+ + hexanoate 0.0 r_2234 peroxisomal acyl-CoA thioesterase (16:1) 0.12566955088586731 prot_P41903 + H2O + palmitoleoyl-CoA(4-) --> coenzyme A + H+ + palmitoleate 0.0 r_2235 peroxisomal acyl-CoA thioesterase (18:1) 0.12566955088586731 prot_P41903 + H2O + oleoyl-CoA --> coenzyme A + H+ + oleate 0.0 -r_2236 acyl-CoA oxidase (butanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + butanoyl-CoA --> hydrogen peroxide + trans-but-2-enoyl-CoA 0.0005698445731318472 -r_2237 acyl-CoA oxidase (hexanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + hexanoyl-CoA --> hydrogen peroxide + trans-hex-2-enoyl-CoA 0.0005698445731318472 -r_2238 acyl-CoA oxidase (octanoyl-CoA) 6.727665706051873 prot_P13711 + octanoyl-CoA + oxygen --> hydrogen peroxide + trans-oct-2-enoyl-CoA 0.0005698445731318472 -r_2239 acyl-CoA oxidase (icosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + icosanoyl-CoA --> hydrogen peroxide + trans-icos-2-enoyl-CoA 0.00032289641279162194 -r_2240 acyl-CoA oxidase (docosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + docosanoyl-CoA --> hydrogen peroxide + trans-docos-2-enoyl-CoA 0.00032289641279162194 -r_2241 acyl-CoA oxidase (tetracosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + tetracosanoyl-CoA --> hydrogen peroxide + trans-tetracos-2-enoyl-CoA 0.00032289641279162194 -r_2242 acyl-CoA oxidase (palmitoleoyl-CoA) 2.7176949941792783 prot_P13711 + 4.0 H+ + oxygen + palmitoleoyl-CoA(4-) --> hydrogen peroxide + trans-2,cis-9-hexadecadienoyl-CoA 0.0005698445731318472 -r_2243 acyl-CoA oxidase (cis-tetradec-7-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-tetradec-7-enoyl-CoA --> hydrogen peroxide + trans-2,cis-7-tetradecadienoyl-CoA 0.0005698445731318472 -r_2244 acyl-CoA oxidase (cis-dodec-5-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-dodec-5-enoyl-CoA --> hydrogen peroxide + trans-2,cis-5-dodecadienoyl-CoA 0.0005698445731318472 +r_2236 acyl-CoA oxidase (butanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + butanoyl-CoA --> hydrogen peroxide + trans-but-2-enoyl-CoA 0.00016913831181727956 +r_2237 acyl-CoA oxidase (hexanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + hexanoyl-CoA --> hydrogen peroxide + trans-hex-2-enoyl-CoA 0.00016913831181727956 +r_2238 acyl-CoA oxidase (octanoyl-CoA) 6.727665706051873 prot_P13711 + octanoyl-CoA + oxygen --> hydrogen peroxide + trans-oct-2-enoyl-CoA 0.00016913831181727956 +r_2239 acyl-CoA oxidase (icosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + icosanoyl-CoA --> hydrogen peroxide + trans-icos-2-enoyl-CoA 0.0 +r_2240 acyl-CoA oxidase (docosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + docosanoyl-CoA --> hydrogen peroxide + trans-docos-2-enoyl-CoA 0.0 +r_2241 acyl-CoA oxidase (tetracosanoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + tetracosanoyl-CoA --> hydrogen peroxide + trans-tetracos-2-enoyl-CoA 0.0 +r_2242 acyl-CoA oxidase (palmitoleoyl-CoA) 2.7176949941792783 prot_P13711 + 4.0 H+ + oxygen + palmitoleoyl-CoA(4-) --> hydrogen peroxide + trans-2,cis-9-hexadecadienoyl-CoA 0.00016913831181727956 +r_2243 acyl-CoA oxidase (cis-tetradec-7-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-tetradec-7-enoyl-CoA --> hydrogen peroxide + trans-2,cis-7-tetradecadienoyl-CoA 0.00016913831181727956 +r_2244 acyl-CoA oxidase (cis-dodec-5-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-dodec-5-enoyl-CoA --> hydrogen peroxide + trans-2,cis-5-dodecadienoyl-CoA 0.00016913831181727956 r_2245 acyl-CoA oxidase (oleoyl-CoA) 2.7176949941792783 prot_P13711 + oleoyl-CoA + oxygen --> hydrogen peroxide + trans-2,cis-9-octadecadienoyl-CoA 0.0 r_2246 acyl-CoA oxidase (cis-hexadec-7-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-hexadec-7-enoyl-CoA --> hydrogen peroxide + trans-2,cis-7-hexadecadienoyl-CoA 0.0 r_2247 acyl-CoA oxidase (cis-tetradec-5-enoyl-CoA) 2.7176949941792783 prot_P13711 + oxygen + cis-tetradec-5-enoyl-CoA --> hydrogen peroxide + trans-2,cis-5-tetradecadienoyl-CoA 0.0 -r_2248 2-enoyl-CoA hydratase (3-hydroxydecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dec-2-enoyl-CoA --> (R)-3-hydroxydecanoyl-CoA 0.0005698445731318472 -r_2249 2-enoyl-CoA hydratase (3-hydroxydodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dodec-2-enoyl-CoA --> (R)-3-hydroxylauroyl-CoA 0.0 -r_2250 2-enoyl-CoA hydratase (3-hydroxytetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetradec-2-enoyl-CoA --> (S)-3-hydroxytetradecanoyl-CoA 0.000536549525352524 -r_2251 2-enoyl-CoA hydratase (3-hydroxyhexadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + hexadec-2-enoyl-CoA --> (S)-3-hydroxypalmitoyl-CoA 0.0007372482900567666 -r_2252 2-enoyl-CoA hydratase (3-hydroxyoctadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-octadec-2-enoyl-CoA --> 3-hydroxyoctadecanoyl-CoA 0.0007372482901629971 -r_2253 2-enoyl-CoA hydratase (3-hydroxyhexacosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hexacos-2-enoyl-CoA --> (S)-3-hydroxyhexacosanoyl-CoA 0.00032289641279162194 -r_2254 2-enoyl-CoA hydratase (3-hydroxybutanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-but-2-enoyl-CoA --> (R)-3-hydroxybutanoyl-CoA 0.0005698445731318472 -r_2255 2-enoyl-CoA hydratase (3-hydroxyhexanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hex-2-enoyl-CoA --> (R)-3-hydroxyhexanoyl-CoA 0.0005698445731318472 -r_2256 2-enoyl-CoA hydratase (3-hydroxyoctanoyl-CoA) 0.07066365979381443 prot_Q02207 + 4.0 H+ + H2O + trans-oct-2-enoyl-CoA --> (R)-3-hydroxyoctanoyl-CoA 0.0005698445731318472 -r_2257 2-enoyl-CoA hydratase (3-hydroxyicosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-icos-2-enoyl-CoA --> (R)-3-hydroxyicosanoyl-CoA 0.00032289641279162194 -r_2258 2-enoyl-CoA hydratase (3-hydroxydocosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-docos-2-enoyl-CoA --> (R)-3-hydroxydocosanoyl-CoA 0.00032289641279162194 -r_2259 2-enoyl-CoA hydratase (3-hydroxytetracosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetracos-2-enoyl-CoA --> (R)-3-hydroxytetracosanoyl-CoA 0.00032289641279162194 -r_2260 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-9-hexadecadienoyl-CoA --> (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA 0.0005698445731318472 -r_2261 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-7-tetradecadienoyl-CoA --> (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA 0.0005698445731318472 -r_2262 2-enoyl-CoA hydratase (3-hydroxy-cis-dodec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-5-dodecadienoyl-CoA --> (R)-3-hydroxy-cis-dodec-5-enoyl-CoA 0.0005698445731318472 +r_2248 2-enoyl-CoA hydratase (3-hydroxydecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dec-2-enoyl-CoA --> (R)-3-hydroxydecanoyl-CoA 0.00016913831181727956 +r_2249 2-enoyl-CoA hydratase (3-hydroxydodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-dodec-2-enoyl-CoA --> (R)-3-hydroxylauroyl-CoA 0.00016913831181727956 +r_2250 2-enoyl-CoA hydratase (3-hydroxytetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetradec-2-enoyl-CoA --> (S)-3-hydroxytetradecanoyl-CoA 0.0 +r_2251 2-enoyl-CoA hydratase (3-hydroxyhexadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + hexadec-2-enoyl-CoA --> (S)-3-hydroxypalmitoyl-CoA 0.0 +r_2252 2-enoyl-CoA hydratase (3-hydroxyoctadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-octadec-2-enoyl-CoA --> 3-hydroxyoctadecanoyl-CoA 0.0 +r_2253 2-enoyl-CoA hydratase (3-hydroxyhexacosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hexacos-2-enoyl-CoA --> (S)-3-hydroxyhexacosanoyl-CoA 0.0 +r_2254 2-enoyl-CoA hydratase (3-hydroxybutanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-but-2-enoyl-CoA --> (R)-3-hydroxybutanoyl-CoA 0.00016913831181727956 +r_2255 2-enoyl-CoA hydratase (3-hydroxyhexanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-hex-2-enoyl-CoA --> (R)-3-hydroxyhexanoyl-CoA 0.00016913831181727956 +r_2256 2-enoyl-CoA hydratase (3-hydroxyoctanoyl-CoA) 0.07066365979381443 prot_Q02207 + 4.0 H+ + H2O + trans-oct-2-enoyl-CoA --> (R)-3-hydroxyoctanoyl-CoA 0.00016913831181727956 +r_2257 2-enoyl-CoA hydratase (3-hydroxyicosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-icos-2-enoyl-CoA --> (R)-3-hydroxyicosanoyl-CoA 0.0 +r_2258 2-enoyl-CoA hydratase (3-hydroxydocosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-docos-2-enoyl-CoA --> (R)-3-hydroxydocosanoyl-CoA 0.0 +r_2259 2-enoyl-CoA hydratase (3-hydroxytetracosanoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-tetracos-2-enoyl-CoA --> (R)-3-hydroxytetracosanoyl-CoA 0.0 +r_2260 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-9-hexadecadienoyl-CoA --> (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA 0.00016913831181727956 +r_2261 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-7-tetradecadienoyl-CoA --> (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA 0.00016913831181727956 +r_2262 2-enoyl-CoA hydratase (3-hydroxy-cis-dodec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-5-dodecadienoyl-CoA --> (R)-3-hydroxy-cis-dodec-5-enoyl-CoA 0.0 r_2263 2-enoyl-CoA hydratase (3-hydroxy-cis-octadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + 4.0 H+ + H2O + trans-2,cis-9-octadecadienoyl-CoA --> (R)-3-hydroxy-cis-octadec-9-enoyl-CoA 0.0 r_2264 2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-7-hexadecadienoyl-CoA --> (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA 0.0 r_2265 2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + H2O + trans-2,cis-5-tetradecadienoyl-CoA --> (R)-3-hydroxy-cis-tetradec-5-enoyl-CoA 0.0 -r_2266 3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxydecanoyl-CoA + NAD --> 3-oxodecanoyl-CoA + H+ + NADH 0.0005698445731318472 -r_2267 3-hydroxyacyl-CoA dehydrogenase (3-oxododecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxylauroyl-CoA + NAD --> 3-oxolauroyl-CoA + H+ + NADH 0.0 -r_2268 3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxypalmitoyl-CoA + NAD --> 3-oxopalmitoyl-CoA + H+ + NADH 0.0007372482900567666 -r_2269 3-hydroxyacyl-CoA dehydrogenase (3-oxooctadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + 3-hydroxyoctadecanoyl-CoA + NAD --> 3-oxooctadecanoyl-CoA + H+ + NADH 0.0007372482901629971 -r_2270 3-hydroxyacyl-CoA dehydrogenase (3-oxohexacosanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxyhexacosanoyl-CoA + NAD --> 3-oxohexacosanoyl-CoA + H+ + NADH 0.00032289641279162194 -r_2271 3-hydroxyacyl-CoA dehydrogenase (3-oxobutanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxybutanoyl-CoA --> H+ + NADH + acetoacetyl-CoA 0.0005698445731318472 -r_2272 3-hydroxyacyl-CoA dehydrogenase (3-oxohexanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyhexanoyl-CoA --> H+ + NADH + 3-oxohexanoyl-CoA 0.0005698445731318472 -r_2273 3-hydroxyacyl-CoA dehydrogenase (3-oxooctanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyoctanoyl-CoA --> H+ + NADH + 3-oxooctanoyl-CoA 0.0005698445731318472 -r_2274 3-hydroxyacyl-CoA dehydrogenase (3-oxoicosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyicosanoyl-CoA --> H+ + NADH + 3-oxoicosanoyl-CoA 0.00032289641279162194 -r_2275 3-hydroxyacyl-CoA dehydrogenase (3-oxodocosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxydocosanoyl-CoA --> H+ + NADH + 3-oxodocosanoyl-CoA 0.00032289641279162194 -r_2276 3-hydroxyacyl-CoA dehydrogenase (3-oxotetracosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxytetracosanoyl-CoA --> H+ + NADH + 3-oxotetracosanoyl-CoA 0.00032289641279162194 -r_2277 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA --> H+ + NADH + 3-oxo-cis-hexadec-9-enoyl-CoA 0.0005698445731318472 -r_2278 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA --> H+ + NADH + 3-oxo-cis-tetradec-7-enoyl-CoA 0.0005698445731318472 -r_2279 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-dodec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-dodec-5-enoyl-CoA --> H+ + NADH + 3-oxo-cis-dodec-5-enoyl-CoA 0.0005698445731318472 +r_2266 3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxydecanoyl-CoA + NAD --> 3-oxodecanoyl-CoA + H+ + NADH 0.00016913831181727956 +r_2267 3-hydroxyacyl-CoA dehydrogenase (3-oxododecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (R)-3-hydroxylauroyl-CoA + NAD --> 3-oxolauroyl-CoA + H+ + NADH 0.00016913831181727956 +r_2268 3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxypalmitoyl-CoA + NAD --> 3-oxopalmitoyl-CoA + H+ + NADH 0.0 +r_2269 3-hydroxyacyl-CoA dehydrogenase (3-oxooctadecanoyl-CoA) 0.07066365979381443 prot_Q02207 + 3-hydroxyoctadecanoyl-CoA + NAD --> 3-oxooctadecanoyl-CoA + H+ + NADH 0.0 +r_2270 3-hydroxyacyl-CoA dehydrogenase (3-oxohexacosanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxyhexacosanoyl-CoA + NAD --> 3-oxohexacosanoyl-CoA + H+ + NADH 0.0 +r_2271 3-hydroxyacyl-CoA dehydrogenase (3-oxobutanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxybutanoyl-CoA --> H+ + NADH + acetoacetyl-CoA 0.00016913831181727956 +r_2272 3-hydroxyacyl-CoA dehydrogenase (3-oxohexanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyhexanoyl-CoA --> H+ + NADH + 3-oxohexanoyl-CoA 0.00016913831181727956 +r_2273 3-hydroxyacyl-CoA dehydrogenase (3-oxooctanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyoctanoyl-CoA --> H+ + NADH + 3-oxooctanoyl-CoA 0.00016913831181727956 +r_2274 3-hydroxyacyl-CoA dehydrogenase (3-oxoicosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxyicosanoyl-CoA --> H+ + NADH + 3-oxoicosanoyl-CoA 0.0 +r_2275 3-hydroxyacyl-CoA dehydrogenase (3-oxodocosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxydocosanoyl-CoA --> H+ + NADH + 3-oxodocosanoyl-CoA 0.0 +r_2276 3-hydroxyacyl-CoA dehydrogenase (3-oxotetracosanoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxytetracosanoyl-CoA --> H+ + NADH + 3-oxotetracosanoyl-CoA 0.0 +r_2277 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA --> H+ + NADH + 3-oxo-cis-hexadec-9-enoyl-CoA 0.00016913831181727956 +r_2278 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA --> H+ + NADH + 3-oxo-cis-tetradec-7-enoyl-CoA 0.00016913831181727956 +r_2279 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-dodec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-dodec-5-enoyl-CoA --> H+ + NADH + 3-oxo-cis-dodec-5-enoyl-CoA 0.0 r_2280 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-octadec-9-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-octadec-9-enoyl-CoA --> H+ + NADH + 3-oxo-cis-octadec-9-enoyl-CoA 0.0 r_2281 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-7-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA --> H+ + NADH + 3-oxo-cis-hexadec-7-enoyl-CoA 0.0 r_2282 3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-5-enoyl-CoA) 0.07066365979381443 prot_Q02207 + NAD + (R)-3-hydroxy-cis-tetradec-5-enoyl-CoA --> H+ + NADH + 3-oxo-cis-tetradec-5-enoyl-CoA 0.0 -r_2283 acetyl-CoA C-acyltransferase (acetyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + acetoacetyl-CoA --> 2.0 acetyl-CoA 0.0005698445731318472 -r_2284 acetyl-CoA C-acyltransferase (butanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxohexanoyl-CoA --> acetyl-CoA + 4.0 H+ + butanoyl-CoA 0.0005698445731318472 -r_2285 acetyl-CoA C-acyltransferase (hexanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxooctanoyl-CoA --> acetyl-CoA + hexanoyl-CoA 0.0005698445731318472 -r_2286 acetyl-CoA C-acyltransferase (stearoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxoicosanoyl-CoA --> acetyl-CoA + stearoyl-CoA 0.00032289641279162194 -r_2287 acetyl-CoA C-acyltransferase (icosanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxodocosanoyl-CoA --> acetyl-CoA + icosanoyl-CoA 0.00032289641279162194 -r_2288 acetyl-CoA C-acyltransferase (docosanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxotetracosanoyl-CoA --> acetyl-CoA + docosanoyl-CoA 0.00032289641279162194 -r_2289 acetyl-CoA C-acyltransferase (cis-tetradec-7-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-hexadec-9-enoyl-CoA --> acetyl-CoA + cis-tetradec-7-enoyl-CoA 0.0005698445731318472 -r_2290 acetyl-CoA C-acyltransferase (cis-dodec-5-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-tetradec-7-enoyl-CoA --> acetyl-CoA + cis-dodec-5-enoyl-CoA 0.0005698445731318472 -r_2291 acetyl-CoA C-acyltransferase (cis-dec-3-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-dodec-5-enoyl-CoA --> acetyl-CoA + cis-dec-3-enoyl-CoA 0.0005698445731318472 +r_2283 acetyl-CoA C-acyltransferase (acetyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + acetoacetyl-CoA --> 2.0 acetyl-CoA 0.00016913831181727956 +r_2284 acetyl-CoA C-acyltransferase (butanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxohexanoyl-CoA --> acetyl-CoA + 4.0 H+ + butanoyl-CoA 0.00016913831181727956 +r_2285 acetyl-CoA C-acyltransferase (hexanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxooctanoyl-CoA --> acetyl-CoA + hexanoyl-CoA 0.00016913831181727956 +r_2286 acetyl-CoA C-acyltransferase (stearoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxoicosanoyl-CoA --> acetyl-CoA + stearoyl-CoA 0.0 +r_2287 acetyl-CoA C-acyltransferase (icosanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxodocosanoyl-CoA --> acetyl-CoA + icosanoyl-CoA 0.0 +r_2288 acetyl-CoA C-acyltransferase (docosanoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxotetracosanoyl-CoA --> acetyl-CoA + docosanoyl-CoA 0.0 +r_2289 acetyl-CoA C-acyltransferase (cis-tetradec-7-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-hexadec-9-enoyl-CoA --> acetyl-CoA + cis-tetradec-7-enoyl-CoA 0.00016913831181727956 +r_2290 acetyl-CoA C-acyltransferase (cis-dodec-5-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-tetradec-7-enoyl-CoA --> acetyl-CoA + cis-dodec-5-enoyl-CoA 0.00016913831181727956 +r_2291 acetyl-CoA C-acyltransferase (cis-dec-3-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-dodec-5-enoyl-CoA --> acetyl-CoA + cis-dec-3-enoyl-CoA 0.0 r_2292 acetyl-CoA C-acyltransferase (cis-hexadec-7-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-octadec-9-enoyl-CoA --> acetyl-CoA + cis-hexadec-7-enoyl-CoA 0.0 r_2293 acetyl-CoA C-acyltransferase (cis-tetradec-5-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-hexadec-7-enoyl-CoA --> acetyl-CoA + cis-tetradec-5-enoyl-CoA 0.0 r_2294 acetyl-CoA C-acyltransferase (cis-dodec-3-enoyl-CoA) 0.839527027027027 prot_P27796 + coenzyme A + 3-oxo-cis-tetradec-5-enoyl-CoA --> acetyl-CoA + cis-dodec-3-enoyl-CoA 0.0 -r_2295 delta3,delta2-enoyl-CoA isomerase (cis-dec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + cis-dec-3-enoyl-CoA --> 4.0 H+ + trans-dec-2-enoyl-CoA 0.0005698445731318472 -r_2296 delta3,delta2-enoyl-CoA isomerase (trans-2,cis-5-dodecadienoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-2,cis-5-dodecadienoyl-CoA --> trans-3,cis-5-dodecadienoyl-CoA 0.0 -r_2297 delta3,delta2-enoyl-CoA isomerase (trans-dodec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-dodec-3-enoyl-CoA --> 4.0 H+ + trans-dodec-2-enoyl-CoA 0.0 +r_2295 delta3,delta2-enoyl-CoA isomerase (cis-dec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + cis-dec-3-enoyl-CoA --> 4.0 H+ + trans-dec-2-enoyl-CoA 0.0 +r_2296 delta3,delta2-enoyl-CoA isomerase (trans-2,cis-5-dodecadienoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-2,cis-5-dodecadienoyl-CoA --> trans-3,cis-5-dodecadienoyl-CoA 0.00016913831181727956 +r_2297 delta3,delta2-enoyl-CoA isomerase (trans-dodec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-dodec-3-enoyl-CoA --> 4.0 H+ + trans-dodec-2-enoyl-CoA 0.00016913831181727956 r_2298 delta3,delta2-enoyl-CoA isomerase (cis-dodec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + cis-dodec-3-enoyl-CoA --> 4.0 H+ + trans-dodec-2-enoyl-CoA 0.0 r_2299 delta3,delta2-enoyl-CoA isomerase (trans-2,cis-5-tetradecadienoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-2,cis-5-tetradecadienoyl-CoA --> trans-3,cis-5-tetradecadienoyl-CoA 0.0 r_2300 delta3,delta2-enoyl-CoA isomerase (trans-tetradec-3-enoyl-CoA) 1.3546153846153846 prot_Q05871 + trans-tetradec-3-enoyl-CoA --> 4.0 H+ + trans-tetradec-2-enoyl-CoA 0.0 -r_2301 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-dodecadienoyl-CoA) 0.0026092013888888888 prot_Q08558 + trans-3,cis-5-dodecadienoyl-CoA --> trans-2,trans-4-dodecadienoyl-CoA 0.0 +r_2301 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-dodecadienoyl-CoA) 0.0026092013888888888 prot_Q08558 + trans-3,cis-5-dodecadienoyl-CoA --> trans-2,trans-4-dodecadienoyl-CoA 0.00016913831181727956 r_2302 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-tetradecadienoyl-CoA) 0.0026092013888888888 prot_Q08558 + trans-3,cis-5-tetradecadienoyl-CoA --> trans-2,trans-4-tetradecadienoyl-CoA 0.0 -r_2303 2,4-dienoyl-CoA reductase (trans-2,trans-4-dodecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-dodecadienoyl-CoA --> NADP(+) + trans-dodec-3-enoyl-CoA 0.0 +r_2303 2,4-dienoyl-CoA reductase (trans-2,trans-4-dodecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-dodecadienoyl-CoA --> NADP(+) + trans-dodec-3-enoyl-CoA 0.00016913831181727956 r_2304 2,4-dienoyl-CoA reductase (trans-2,trans-4-tetradecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-tetradecadienoyl-CoA --> NADP(+) + trans-tetradec-3-enoyl-CoA 0.0 -r_2305 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 1.6450625360586744 +r_2305 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.8255773085692462 r_2305_REV cis-aconitate(3-) to isocitrate (reversible) 0.16582750582750583 prot_P19414 + isocitrate --> cis-aconitate + H2O 0.0 -r_2308_EXP_1 glycerol-3-phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0031532487220124056 +r_2308_EXP_1 glycerol-3-phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.003153248722094766 r_2308_EXP_2 glycerol-3-phosphate acyltransferase (16:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0 -r_2309_EXP_1 glycerol-3-phosphate acyltransferase (16:1), ER membrane 124.56838874829987 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.003524014239466536 +r_2309_EXP_1 glycerol-3-phosphate acyltransferase (16:1), ER membrane 124.56838874829987 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0035240142393573497 r_2309_EXP_2 glycerol-3-phosphate acyltransferase (16:1), ER membrane 121.5898765007065 prot_P36148 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0 r_2310 glycerol-3-phosphate acyltransferase (18:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + stearoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0 r_2311 glycerol-3-phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 0.0 @@ -2768,7 +2768,7 @@ r_2314 dihydroxyacetone phosphate acyltransferase (18:0), ER membrane 97.6248832 r_2315 dihydroxyacetone phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (18:1) 0.0 r_2316 glycerol-3-phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0 r_2317 glycerol-3-phosphate acyltransferase (16:1), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoleoyl-CoA(4-) --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0 -r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + stearoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0002776698027845354 +r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + stearoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.00027766980278454763 r_2319 glycerol-3-phosphate acyltransferase (18:1), lipid particle 106.58129459734965 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + oleoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 0.0 r_2320 dihydroxyacetone phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + dihydroxyacetone phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + acylglycerone phosphate (16:0) 0.0 r_2321 dihydroxyacetone phosphate acyltransferase (16:1), lipid particle 97.624883286648 prot_P36148 + dihydroxyacetone phosphate + 2.0 H+ + palmitoleoyl-CoA(4-) --> coenzyme A + acylglycerone phosphate (16:1) 0.0 @@ -2782,12 +2782,12 @@ r_2328 acyl dhap reductase (16:0), lipid particle 0.09115 prot_P40471 + H+ + acy r_2329 acyl dhap reductase (16:1), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (16:1) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (16:1) + NADP(+) 0.0 r_2330 acyl dhap reductase (18:0), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (18:0) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (18:0) + NADP(+) 0.0 r_2331 acyl dhap reductase (18:1), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (18:1) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (18:1) + NADP(+) 0.0 -r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-16:1) 0.0023944394904621595 +r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-16:1) 0.0023944394910889112 r_2333_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0 -r_2333_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0007588092315238737 -r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 113.27321041547852 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-16:1) 0.002507587851130412 +r_2333_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0007588092310058545 +r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 113.27321041547852 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-16:1) 0.0025075878505032285 r_2335_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 -r_2335_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0010164263883361208 +r_2335_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0010164263888541281 r_2336 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-16:1) 0.0 r_2337_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 r_2337_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 @@ -2802,7 +2802,7 @@ r_2341_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), li r_2341_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 r_2342_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 r_2342_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 -r_2342_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0002776698027845354 +r_2342_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0002776698027845477 r_2343_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2343_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2343_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 @@ -2822,12 +2822,12 @@ r_2356 PA phosphatase (1-18:0, 2-16:1), vacuolar membrane 0.0963012769674609 pro r_2357 PA phosphatase (1-18:0, 2-18:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0 r_2358 PA phosphatase (1-18:1, 2-16:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:1, 2-16:1) --> phosphate + diglyceride (1-18:1, 2-16:1) + 2.0 H+ 0.0 r_2359 PA phosphatase (1-18:1, 2-18:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:1, 2-18:1) --> phosphate + diglyceride (1-18:1, 2-18:1) + 2.0 H+ 0.0 -r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + phosphatidate (1-16:0, 2-16:1) + H2O --> phosphate + diglyceride (1-16:0, 2-16:1) + 2.0 H+ 0.0023944394904621595 +r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + phosphatidate (1-16:0, 2-16:1) + H2O --> phosphate + diglyceride (1-16:0, 2-16:1) + 2.0 H+ 0.002394439491099864 r_2361 PA phosphatase (1-16:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:0, 2-18:1) --> phosphate + diglyceride (1-16:0, 2-18:1) + 2.0 H+ 0.0 r_2362 PA phosphatase (1-16:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-16:1) --> phosphate + diglyceride (1-16:1, 2-16:1) + 2.0 H+ 0.0 -r_2363 PA phosphatase (1-16:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-18:1) --> phosphate + diglyceride (1-16:1, 2-18:1) + 2.0 H+ 0.0009055405211722131 +r_2363 PA phosphatase (1-16:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-18:1) --> phosphate + diglyceride (1-16:1, 2-18:1) + 2.0 H+ 0.000905540521170951 r_2364 PA phosphatase (1-18:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-16:1) --> phosphate + diglyceride (1-18:0, 2-16:1) + 2.0 H+ 0.0 -r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0002776698027845354 +r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0002776698027845477 r_2366 PA phosphatase (1-18:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:1, 2-16:1) --> phosphate + diglyceride (1-18:1, 2-16:1) + 2.0 H+ 0.0 r_2367 PA phosphatase (1-18:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:1, 2-18:1) --> phosphate + diglyceride (1-18:1, 2-18:1) + 2.0 H+ 0.0 r_2368_EXP_1 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:0), ER membrane 67.08130559354814 prot_P25628 + palmitoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-16:0) 0.0 @@ -2862,7 +2862,7 @@ r_2377_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membran r_2377_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 r_2378_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_2378_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 -r_2378_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0008645167300003441 +r_2378_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.00031730953913846434 r_2379_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2379_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2379_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 @@ -2886,7 +2886,7 @@ r_2385_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membran r_2385_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 r_2386_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 67.08130559354814 prot_P25628 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 r_2386_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 20.519322196722364 prot_P53629 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 -r_2386_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0005189749331324894 +r_2386_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0005189749331324771 r_2387_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 67.08130559354814 prot_P25628 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2387_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 20.519322196722364 prot_P53629 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2387_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 @@ -2960,15 +2960,15 @@ r_2430 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:1), lipid particle 1 r_2431 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-18:1) 0.0 r_2432 CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) 0.0 r_2432_REV CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) --> H+ + phosphatidate (1-16:0, 2-16:1) + CTP 0.0 -r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0018202640151839164 +r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0018202640151948994 r_2433_REV CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) --> H+ + phosphatidate (1-16:1, 2-16:1) + CTP 0.0 r_2434 CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) 0.0 r_2434_REV CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) --> H+ + phosphatidate (1-18:0, 2-16:1) + CTP 0.0 -r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.0034727008626706103 +r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.003472700862670582 r_2435_REV CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) --> H+ + phosphatidate (1-18:1, 2-16:1) + CTP 0.0 -r_2436 CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0007588092315238737 +r_2436 CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0007588092310058545 r_2436_REV CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) --> H+ + phosphatidate (1-16:0, 2-18:1) + CTP 0.0 -r_2437 CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 6.687418258607542e-05 +r_2437 CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 6.687418310534513e-05 r_2437_REV CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) --> H+ + phosphatidate (1-16:1, 2-18:1) + CTP 0.0 r_2438 CDP-diacylglycerol synthase (1-18:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:0, 2-18:1) 0.0 r_2438_REV CDP-diacylglycerol synthase (1-18:0, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:0, 2-18:1) --> H+ + phosphatidate (1-18:0, 2-18:1) + CTP 0.0 @@ -2976,7 +2976,7 @@ r_2439 CDP-diacylglycerol synthase (1-18:1, 2-18:1), ER membrane 1.6138203786746 r_2439_REV CDP-diacylglycerol synthase (1-18:1, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:1, 2-18:1) --> H+ + phosphatidate (1-18:1, 2-18:1) + CTP 0.0 r_2440 CDP-diacylglycerol synthase (1-16:0, 2-16:1), mitochondrial membrane 1.6138203786746388 prot_P38221 + phosphatidate (1-16:0, 2-16:1) + CTP + H+ --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) 0.0 r_2440_REV CDP-diacylglycerol synthase (1-16:0, 2-16:1), mitochondrial membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) + CTP + H+ 0.0 -r_2441 CDP-diacylglycerol synthase (1-16:1, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.000836284472270941 +r_2441 CDP-diacylglycerol synthase (1-16:1, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.0008362844722709414 r_2441_REV CDP-diacylglycerol synthase (1-16:1, 2-16:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) --> CTP + H+ + phosphatidate (1-16:1, 2-16:1) 0.0 r_2442 CDP-diacylglycerol synthase (1-18:0, 2-16:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-18:0, 2-16:1) --> diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) 0.0 r_2442_REV CDP-diacylglycerol synthase (1-18:0, 2-16:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) --> CTP + H+ + phosphatidate (1-18:0, 2-16:1) 0.0 @@ -2984,12 +2984,12 @@ r_2443 CDP-diacylglycerol synthase (1-18:1, 2-16:1), mitochondrial membrane 1.37 r_2443_REV CDP-diacylglycerol synthase (1-18:1, 2-16:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) --> CTP + H+ + phosphatidate (1-18:1, 2-16:1) 0.0 r_2444 CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:0, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0 r_2444_REV CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) --> CTP + H+ + phosphatidate (1-16:0, 2-18:1) 0.0 -r_2445 CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 4.4011684577832406e-05 +r_2445 CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 4.4011684577832006e-05 r_2445_REV CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) --> CTP + H+ + phosphatidate (1-16:1, 2-18:1) 0.0 r_2446 PS synthase (1-16:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 -r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0018202640151839164 +r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0018202640151948994 r_2448 PS synthase (1-18:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0034727008626706103 +r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-16:1) 0.003472700862670582 r_2450 PS synthase (1-16:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 r_2451 PS synthase (1-16:1, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-18:1) 0.0 r_2452 PS synthase (1-18:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-18:1) 0.0 @@ -2998,8 +2998,8 @@ r_2454 PI synthase (1-16:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 r_2455 PI synthase (1-16:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) 0.0 r_2456 PI synthase (1-18:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:0, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 0.0 r_2457 PI synthase (1-18:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 -r_2458 PI synthase (1-16:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0007588092315238737 -r_2459 PI synthase (1-16:1, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 6.687418258607542e-05 +r_2458 PI synthase (1-16:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0007588092310058545 +r_2459 PI synthase (1-16:1, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 6.687418310534513e-05 r_2460 PI synthase (1-18:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) 0.0 r_2461 PI synthase (1-18:1, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:1, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) 0.0 r_2462 lysoPI acyltransferase (1-18:0, 2-16:1), ER membrane 128.62503770539482 prot_P38226 + stearoyl-CoA + sn-2-acyl-1-lysophosphatidylinositol (16:1) --> coenzyme A + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 0.0 @@ -3009,7 +3009,7 @@ r_2463_REV lysoPI acyltransferase (1-18:0, 2-18:1), ER membrane (reversible) 77. r_2464 PS decarboxylase (1-16:0, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-16:1) 0.0 r_2465 PS decarboxylase (1-16:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-16:1) 0.0010072557503258324 r_2466 PS decarboxylase (1-18:0, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_2467 PS decarboxylase (1-18:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.0034727008626706103 +r_2467 PS decarboxylase (1-18:1, 2-16:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.003472700862670582 r_2468 PS decarboxylase (1-16:0, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_2469 PS decarboxylase (1-16:1, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-16:1, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2470 PS decarboxylase (1-18:0, 2-18:1), mitochondrial membrane 0.04287500000000001 prot_P39006 + phosphatidyl-L-serine (1-18:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3033,7 +3033,7 @@ r_2487 PS decarboxylase (1-18:1, 2-18:1), vacuolar membrane 0.09853409090909093 r_2488 PE methyltransferase (1-16:0, 2-16:1), ER membrane 1627.5240996397504 prot_P05374 + phosphatidylethanolamine (1-16:0, 2-16:1) + S-adenosyl-L-methionine --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) 0.0 r_2489 PE methyltransferase (1-16:1, 2-16:1), ER membrane 1772.794398518638 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) 0.0 r_2490 PE methyltransferase (1-18:0, 2-16:1), ER membrane 2311.996703472735 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) 0.0 -r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 169.40036397185034 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) 0.0034727008626706103 +r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 169.40036397185034 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) 0.003472700862670582 r_2492 PE methyltransferase (1-16:0, 2-18:1), ER membrane 1187.9768182494734 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) 0.0 r_2493 PE methyltransferase (1-16:1, 2-18:1), ER membrane 1927.895637345238 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) 0.0 r_2494 PE methyltransferase (1-18:0, 2-18:1), ER membrane 1845.2830881909267 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3041,7 +3041,7 @@ r_2495 PE methyltransferase (1-18:1, 2-18:1), ER membrane 1146.7320397250028 pro r_2496 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) 0.0 r_2497 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) 0.0 r_2498 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) 0.0 -r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) 0.0034727008626706103 +r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) 0.0034727008626705825 r_2500 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) 0.0 r_2501 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) 0.0 r_2502 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3049,7 +3049,7 @@ r_2503 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-18:1), ER r_2504 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2505 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2506 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:0, 2-16:1) 0.0 -r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-16:1) 0.0034727008626706103 +r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-16:1) 0.003472700862670582 r_2508 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_2509 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2510 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:0, 2-18:1) 0.0 @@ -3070,7 +3070,7 @@ r_2524 ethanolaminephosphotransferase (1-16:0, 2-18:1), ER membrane 12.259319894 r_2525 ethanolaminephosphotransferase (1-16:1, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2526 ethanolaminephosphotransferase (1-18:0, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 r_2527 ethanolaminephosphotransferase (1-18:1, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-18:1, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 -r_2528_EXP_1 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.0023944394904621595 +r_2528_EXP_1 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.002394439491099864 r_2528_EXP_2 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2529_EXP_1 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2529_EXP_2 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-16:1) 0.0 @@ -3080,24 +3080,24 @@ r_2531_EXP_1 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 12.68654168 r_2531_EXP_2 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2532_EXP_1 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_2532_EXP_2 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0 -r_2533_EXP_1 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0009495522057500455 +r_2533_EXP_1 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.000949552205748783 r_2533_EXP_2 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0 -r_2534_EXP_1 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0002776698027845354 +r_2534_EXP_1 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0002776698027845477 r_2534_EXP_2 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2535_EXP_1 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_2535_EXP_2 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_2536 phosphatidylglycerolphosphate synthase (1-16:0, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:0, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-16:1) 0.0 -r_2537 phosphatidylglycerolphosphate synthase (1-16:1, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) 0.000836284472270941 +r_2537 phosphatidylglycerolphosphate synthase (1-16:1, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) 0.0008362844722709414 r_2538 phosphatidylglycerolphosphate synthase (1-18:0, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-18:0, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:0, 2-16:1) 0.0 r_2539 phosphatidylglycerolphosphate synthase (1-18:1, 2-16:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-18:1, 2-16:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:1, 2-16:1) 0.0 r_2540 phosphatidylglycerolphosphate synthase (1-16:0, 2-18:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:0, 2-18:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-18:1) 0.0 -r_2541 phosphatidylglycerolphosphate synthase (1-16:1, 2-18:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-18:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) 4.4011684577832406e-05 +r_2541 phosphatidylglycerolphosphate synthase (1-16:1, 2-18:1), mitochondrial membrane 93.03319979360033 prot_P25578 + CDP-diacylglycerol (1-16:1, 2-18:1) + glycerol 3-phosphate --> CMP + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) 4.4011684577832006e-05 r_2542 PGP phosphatase (1-16:0, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-16:1) + H2O --> 2.0 H+ + phosphatidylglycerol (1-16:0, 2-16:1) + phosphate 0.0 -r_2543 PGP phosphatase (1-16:1, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-16:1) 0.000836284472270941 +r_2543 PGP phosphatase (1-16:1, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-16:1) 0.0008362844722709414 r_2544 PGP phosphatase (1-18:0, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:0, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-18:0, 2-16:1) 0.0 r_2545 PGP phosphatase (1-18:1, 2-16:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:1, 2-16:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-18:1, 2-16:1) 0.0 r_2546 PGP phosphatase (1-16:0, 2-18:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-18:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:0, 2-18:1) 0.0 -r_2547 PGP phosphatase (1-16:1, 2-18:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-18:1) 4.4011684577832406e-05 +r_2547 PGP phosphatase (1-16:1, 2-18:1), mitochondrial membrane 0.24241898148148147 prot_P38812 + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) + H2O --> 2.0 H+ + phosphate + phosphatidylglycerol (1-16:1, 2-18:1) 4.4011684577832006e-05 r_2548 CL synthase (1-16:0, 2-16:1, 3-16:0, 4-16:1), mitochondrial membrane 4334.5245830625945 prot_Q07560 + CDP-diacylglycerol (1-16:0, 2-16:1) + phosphatidylglycerol (1-16:0, 2-16:1) --> 2.0 H+ + CMP + cardiolipin (1-16:0, 2-16:1, 3-16:0, 4-16:1) 0.0 r_2549 CL synthase (1-16:0, 2-16:1, 3-16:1, 4-16:1), mitochondrial membrane 4334.5245830625945 prot_Q07560 + CDP-diacylglycerol (1-16:0, 2-16:1) + phosphatidylglycerol (1-16:1, 2-16:1) --> 2.0 H+ + CMP + cardiolipin (1-16:0, 2-16:1, 3-16:1, 4-16:1) 0.0 r_2550 CL synthase (1-16:0, 2-16:1, 3-18:0, 4-16:1), mitochondrial membrane 4334.5245830625945 prot_Q07560 + CDP-diacylglycerol (1-16:0, 2-16:1) + phosphatidylglycerol (1-18:0, 2-16:1) --> 2.0 H+ + CMP + cardiolipin (1-16:0, 2-16:1, 3-18:0, 4-16:1) 0.0 @@ -3186,17 +3186,17 @@ r_2626 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitoch r_2626_REV MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (18:0) --> monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2627 MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-18:1, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2627_REV MLCL (2-16:1, 3-16:0, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:0, 4-16:1) + 1-acylglycerophosphocholine (18:1) --> monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) + phosphatidylcholine (1-18:1, 2-18:1) 0.0 -r_2628 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 +r_2628 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.00014896063696261247 r_2628_REV MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2629 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.0 -r_2629_REV MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) 7.44803181622224e-05 +r_2629_REV MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) 0.00014896063696261247 r_2630 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) 0.0 r_2630_REV MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) --> monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_2631 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2631_REV MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) --> monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2632 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 -r_2632_REV MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 0.0 -r_2633 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 7.44803181622224e-05 +r_2632_REV MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 0.00014896063696261247 +r_2633 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.00014896063696261247 r_2633_REV MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2634 MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) 0.0 r_2634_REV MLCL (2-16:1, 3-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) --> monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) 0.0 @@ -3218,7 +3218,7 @@ r_2642 MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitoch r_2642_REV MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:0, 4-16:1) + 1-acylglycerophosphocholine (18:0) --> monolysocardiolipin (2-16:1, 3-18:0, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2643 MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:0, 4-16:1) + phosphatidylcholine (1-18:1, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:0, 4-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2643_REV MLCL (2-16:1, 3-18:0, 4-16:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:0, 4-16:1) + 1-acylglycerophosphocholine (18:1) --> monolysocardiolipin (2-16:1, 3-18:0, 4-16:1) + phosphatidylcholine (1-18:1, 2-18:1) 0.0 -r_2644 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 7.44803181622224e-05 +r_2644 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 r_2644_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2645 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.0 r_2645_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) 0.0 @@ -3227,7 +3227,7 @@ r_2646_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mi r_2647 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2647_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2648 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 -r_2648_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 7.44803181622224e-05 +r_2648_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_2649 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.0 r_2649_REV MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2650 MLCL (2-16:1, 3-18:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) 0.0 @@ -3394,7 +3394,7 @@ r_2730 MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitoch r_2730_REV MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + 1-acylglycerophosphocholine (18:0) + cardiolipin (1-16:0, 2-16:1, 3-18:1, 4-18:1) --> monolysocardiolipin (1-16:0, 2-16:1, 4-18:1) + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2731 MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:0, 2-16:1, 4-18:1) + phosphatidylcholine (1-18:1, 2-18:1) --> 1-acylglycerophosphocholine (18:1) + cardiolipin (1-16:0, 2-16:1, 3-18:1, 4-18:1) 0.0 r_2731_REV MLCL (1-16:0, 2-16:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + 1-acylglycerophosphocholine (18:1) + cardiolipin (1-16:0, 2-16:1, 3-18:1, 4-18:1) --> monolysocardiolipin (1-16:0, 2-16:1, 4-18:1) + phosphatidylcholine (1-18:1, 2-18:1) 0.0 -r_2732 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 7.44803181622224e-05 +r_2732 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 r_2732_REV MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2733 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.0 r_2733_REV MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) 0.0 @@ -3403,7 +3403,7 @@ r_2734_REV MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mi r_2735 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) --> cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2735_REV MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) --> monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2736 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) --> cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 -r_2736_REV MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 7.44803181622224e-05 +r_2736_REV MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_2737 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) --> cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.0 r_2737_REV MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2738 MLCL (1-16:1, 2-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) --> cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) 0.0 @@ -3461,14 +3461,14 @@ r_2763_REV MLCL (1-18:0, 2-16:1, 4-18:1):PC (1-18:1, 2-18:1) acyltransferase, mi r_2764 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) --> cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 r_2764_REV MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:0, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2765 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) --> cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.0 -r_2765_REV MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) 7.44803181622224e-05 +r_2765_REV MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2766 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-16:1) --> cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) 0.0 r_2766_REV MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-18:0, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) --> monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_2767 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) --> cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) 0.0 r_2767_REV MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-18:1, 2-16:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) + 1-acylglycerophosphocholine (18:1) --> monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2768 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) 0.0 r_2768_REV MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:0) --> monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:0, 2-18:1) 0.0 -r_2769 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 7.44803181622224e-05 +r_2769 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) 0.0 r_2769_REV MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-16:1, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (16:1) --> monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2770 MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane 0.04273831631073971 prot_Q06510 + monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) --> cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) 0.0 r_2770_REV MLCL (1-18:1, 2-16:1, 4-16:1):PC (1-18:0, 2-18:1) acyltransferase, mitochondrial membrane (reversible) 0.04273831631073971 prot_Q06510 + cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) + 1-acylglycerophosphocholine (18:0) --> monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) + phosphatidylcholine (1-18:0, 2-18:1) 0.0 @@ -4007,15 +4007,15 @@ r_3095 PI 4,5-P2 phospholipase C (1-16:1, 2-18:1), nucleus 0.0321987491713981 pr r_3096 PI 4,5-P2 phospholipase C (1-18:0, 2-18:1), nucleus 0.0321987491713981 prot_P32383 + H2O + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) --> 1D-myo-inositol 1,4,5-trisphosphate + 6.0 H+ + diglyceride (1-18:0, 2-18:1) 0.0 r_3097 PI 4,5-P2 phospholipase C (1-18:1, 2-18:1), nucleus 0.0321987491713981 prot_P32383 + H2O + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) --> 1D-myo-inositol 1,4,5-trisphosphate + 6.0 H+ + diglyceride (1-18:1, 2-18:1) 0.0 r_3098 PG phospholipase C (1-16:0, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:0, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:0, 2-16:1) 0.0 -r_3099 PG phospholipase C (1-16:1, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-16:1) 0.000836284472270941 +r_3099 PG phospholipase C (1-16:1, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-16:1) 0.0008362844722709414 r_3100 PG phospholipase C (1-18:0, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-18:0, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-18:0, 2-16:1) 0.0 r_3101 PG phospholipase C (1-18:1, 2-16:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-18:1, 2-16:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-18:1, 2-16:1) 0.0 r_3102 PG phospholipase C (1-16:0, 2-18:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:0, 2-18:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:0, 2-18:1) 0.0 -r_3103 PG phospholipase C (1-16:1, 2-18:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-18:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-18:1) 4.4011684577832406e-05 +r_3103 PG phospholipase C (1-16:1, 2-18:1), mitochondrial membrane 0.49034391534391536 prot_Q08959 + H2O + phosphatidylglycerol (1-16:1, 2-18:1) --> 2.0 H+ + glycerol 3-phosphate + diglyceride (1-16:1, 2-18:1) 4.4011684577832006e-05 r_3104 PC phospholipase D (1-16:0, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + phosphatidylcholine (1-16:0, 2-16:1) + H2O --> choline + phosphatidate (1-16:0, 2-16:1) 0.0 -r_3105 PC phospholipase D (1-16:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-16:1) --> choline + phosphatidate (1-16:1, 2-16:1) 0.0001489606363244448 +r_3105 PC phospholipase D (1-16:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-16:1) --> choline + phosphatidate (1-16:1, 2-16:1) 0.0001489606369626125 r_3106 PC phospholipase D (1-18:0, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:0, 2-16:1) --> choline + phosphatidate (1-18:0, 2-16:1) 0.0 -r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:1, 2-16:1) --> choline + phosphatidate (1-18:1, 2-16:1) 0.0034727008626706103 +r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:1, 2-16:1) --> choline + phosphatidate (1-18:1, 2-16:1) 0.003472700862670582 r_3108 PC phospholipase D (1-16:0, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:0, 2-18:1) --> choline + phosphatidate (1-16:0, 2-18:1) 0.0 r_3109 PC phospholipase D (1-16:1, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-18:1) --> choline + phosphatidate (1-16:1, 2-18:1) 0.0 r_3110 PC phospholipase D (1-18:0, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:0, 2-18:1) --> choline + phosphatidate (1-18:0, 2-18:1) 0.0 @@ -4260,7 +4260,7 @@ r_3258 lanosteryl ester hydrolase (16:1), lipid particle 1.2983099646771479 prot r_3259 lanosteryl ester hydrolase (18:1), lipid particle 1.2983099646771479 prot_Q07804 + H2O + lanosteryl oleate --> H+ + oleate + lanosterol 0.0 r_3260 zymosteryl ester hydrolase (16:1), lipid particle 1.2983099646771479 prot_Q07804 + H2O + zymosteryl palmitoleate --> H+ + zymosterol + palmitoleate 0.0 r_3261 zymosteryl ester hydrolase (18:1), lipid particle 1.2983099646771479 prot_Q07804 + H2O + zymosteryl oleate --> H+ + zymosterol + oleate 0.0 -r_3262 zymosteryl ester hydrolase (16:1), cell envelope 1.7860318196138645 prot_Q07950 + H2O + zymosteryl palmitoleate --> H+ + zymosterol + palmitoleate 3.687743221822545e-05 +r_3262 zymosteryl ester hydrolase (16:1), cell envelope 1.7860318196138645 prot_Q07950 + H2O + zymosteryl palmitoleate --> H+ + zymosterol + palmitoleate 0.0 r_3263 zymosteryl ester hydrolase (18:1), cell envelope 1.7860318196138645 prot_Q07950 + H2O + zymosteryl oleate --> H+ + zymosterol + oleate 0.0 r_3264_EXP_1 TAG lipase (1-16:0, 2-16:1, 3-16:0), lipid particle 0.9775745257452575 prot_P38139 + triglyceride (1-16:0, 2-16:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:0, 2-16:1) 0.0 r_3264_EXP_2 TAG lipase (1-16:0, 2-16:1, 3-16:0), lipid particle 2.3197154471544716 prot_P36165 + triglyceride (1-16:0, 2-16:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:0, 2-16:1) 0.0 @@ -4283,7 +4283,7 @@ r_3268_EXP_1 TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle 0.9775745257452 r_3268_EXP_2 TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle 2.3197154471544716 prot_P36165 + triglyceride (1-16:1, 2-16:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:1, 2-16:1) 0.0 r_3268_EXP_3 TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle 1.6624435411020777 prot_P40308 + triglyceride (1-16:1, 2-16:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:1, 2-16:1) 0.0 r_3268_EXP_4 TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle 1.9131887985546523 prot_Q12043 + triglyceride (1-16:1, 2-16:1, 3-16:0) + H2O --> H+ + palmitate + diglyceride (1-16:1, 2-16:1) 0.0 -r_3269_EXP_1 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 0.9775745257452575 prot_P38139 + triglyceride (1-16:1, 2-16:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:1, 2-16:1) 0.0005472071908618926 +r_3269_EXP_1 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 0.9775745257452575 prot_P38139 + triglyceride (1-16:1, 2-16:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:1, 2-16:1) 0.0 r_3269_EXP_2 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 2.3197154471544716 prot_P36165 + triglyceride (1-16:1, 2-16:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:1, 2-16:1) 0.0 r_3269_EXP_3 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 1.6624435411020777 prot_P40308 + triglyceride (1-16:1, 2-16:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:1, 2-16:1) 0.0 r_3269_EXP_4 TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle 1.9131887985546523 prot_Q12043 + triglyceride (1-16:1, 2-16:1, 3-16:1) + H2O --> H+ + palmitoleate + diglyceride (1-16:1, 2-16:1) 0.0 @@ -4620,9 +4620,9 @@ r_3504 IPC synthase (PI (1-16:0, 2-18:1) ceramide-4 (C26)) 142.7071089252805 pro r_3505 IPC synthase (PI (1-16:1, 2-18:1) ceramide-4 (C26)) 142.7071089252805 prot_P36107 + 80.47148814754162 prot_Q06346 + ceramide-4 (C26) + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> inositol-P-ceramide D (C26) + diglyceride (1-16:1, 2-18:1) 0.0 r_3506 IPC synthase (PI (1-18:0, 2-18:1) ceramide-4 (C26)) 142.7071089252805 prot_P36107 + 80.47148814754162 prot_Q06346 + ceramide-4 (C26) + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> inositol-P-ceramide D (C26) + diglyceride (1-18:0, 2-18:1) 0.0 r_3507 IPC synthase (PI (1-18:1, 2-18:1) ceramide-4 (C26)) 142.7071089252805 prot_P36107 + 80.47148814754162 prot_Q06346 + ceramide-4 (C26) + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> inositol-P-ceramide D (C26) + diglyceride (1-18:1, 2-18:1) 0.0 -r_3508 laurate transport, cytoplasm-ER membrane laurate --> laurate 0.0005365495253866761 +r_3508 laurate transport, cytoplasm-ER membrane laurate --> laurate 0.0 r_3508_REV laurate transport, cytoplasm-ER membrane (reversible) laurate --> laurate 0.0 -r_3509 myristate transport, cytoplasm-ER membrane myristate --> myristate 0.0002006987647042427 +r_3509 myristate transport, cytoplasm-ER membrane myristate --> myristate 0.0 r_3509_REV myristate transport, cytoplasm-ER membrane (reversible) myristate --> myristate 0.0 r_3510 palmitate transport, cytoplasm-ER membrane palmitate --> palmitate 0.0 r_3510_REV palmitate transport, cytoplasm-ER membrane (reversible) palmitate --> palmitate 0.0 @@ -4632,20 +4632,20 @@ r_3512 stearate transport, cytoplasm-ER membrane stearate --> stearate 0.0 r_3512_REV stearate transport, cytoplasm-ER membrane (reversible) stearate --> stearate 0.0 r_3513 oleate transport, cytoplasm-ER membrane oleate --> oleate 0.0 r_3513_REV oleate transport, cytoplasm-ER membrane (reversible) oleate --> oleate 0.0 -r_3514 malonyl-CoA transport, cytoplasm-ER membrane malonyl-CoA --> malonyl-CoA 0.002565383466644089 +r_3514 malonyl-CoA transport, cytoplasm-ER membrane malonyl-CoA --> malonyl-CoA 0.0038790033786066103 r_3514_REV malonyl-CoA transport, cytoplasm-ER membrane (reversible) malonyl-CoA --> malonyl-CoA 0.0 -r_3515 lauroyl-CoA transport, cytoplasm-ER membrane lauroyl-CoA --> lauroyl-CoA 0.0005365495253866761 +r_3515 lauroyl-CoA transport, cytoplasm-ER membrane lauroyl-CoA --> lauroyl-CoA 0.0 r_3515_REV lauroyl-CoA transport, cytoplasm-ER membrane (reversible) lauroyl-CoA --> lauroyl-CoA 0.0 r_3516 myristoyl-CoA transport, cytoplasm-ER membrane myristoyl-CoA --> myristoyl-CoA 0.0 r_3516_REV myristoyl-CoA transport, cytoplasm-ER membrane (reversible) myristoyl-CoA --> myristoyl-CoA 0.0 -r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane palmitoyl-CoA --> palmitoyl-CoA 0.012313280748221392 +r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane palmitoyl-CoA --> palmitoyl-CoA 0.01652882615566449 r_3517_REV palmitoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3518 palmitoleoyl-CoA transport, cytoplasm-ER membrane palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 -r_3518_REV palmitoleoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0005698445731318472 -r_3519 stearoyl-CoA transport, cytoplasm-ER membrane stearoyl-CoA --> stearoyl-CoA 0.003924229988584005 -r_3519_REV stearoyl-CoA transport, cytoplasm-ER membrane (reversible) stearoyl-CoA --> stearoyl-CoA 0.0 +r_3518_REV palmitoleoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0007532229348973988 +r_3519 stearoyl-CoA transport, cytoplasm-ER membrane stearoyl-CoA --> stearoyl-CoA 0.0 +r_3519_REV stearoyl-CoA transport, cytoplasm-ER membrane (reversible) stearoyl-CoA --> stearoyl-CoA 0.0002776698027845477 r_3520 oleoyl-CoA transport, cytoplasm-ER membrane oleoyl-CoA --> oleoyl-CoA 0.0 -r_3520_REV oleoyl-CoA transport, cytoplasm-ER membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.0002776698027845354 +r_3520_REV oleoyl-CoA transport, cytoplasm-ER membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.0002776698027845477 r_3521 icosanoyl-CoA transport, cytoplasm-ER membrane icosanoyl-CoA --> icosanoyl-CoA 0.0 r_3521_REV icosanoyl-CoA transport, cytoplasm-ER membrane (reversible) icosanoyl-CoA --> icosanoyl-CoA 0.0 r_3522 docosanoyl-CoA transport, cytoplasm-ER membrane docosanoyl-CoA --> docosanoyl-CoA 0.0 @@ -4653,57 +4653,57 @@ r_3522_REV docosanoyl-CoA transport, cytoplasm-ER membrane (reversible) docosano r_3523 tetracosanoyl-CoA transport, cytoplasm-ER membrane tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 r_3523_REV tetracosanoyl-CoA transport, cytoplasm-ER membrane (reversible) tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 r_3524 hexacosanoyl-CoA transport, cytoplasm-ER membrane hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 -r_3524_REV hexacosanoyl-CoA transport, cytoplasm-ER membrane (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.00032289641279162194 -r_3525 H+ transport, cytoplasm-ER membrane H+ --> H+ 0.003253380476513609 +r_3524_REV hexacosanoyl-CoA transport, cytoplasm-ER membrane (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 +r_3525 H+ transport, cytoplasm-ER membrane H+ --> H+ 0.00690416624767446 r_3525_REV H+ transport, cytoplasm-ER membrane (reversible) H+ --> H+ 0.0 r_3526_EXP_1 H2O transport, cytoplasm-ER membrane 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_3526_EXP_2 H2O transport, cytoplasm-ER membrane 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_3526_REV_EXP_1 H2O transport, cytoplasm-ER membrane (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.028524661384563714 +r_3526_REV_EXP_1 H2O transport, cytoplasm-ER membrane (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0290368687738749 r_3526_REV_EXP_2 H2O transport, cytoplasm-ER membrane (reversible) 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_3527 CO2 transport, cytoplasm-ER membrane carbon dioxide --> carbon dioxide 0.0 -r_3527_REV CO2 transport, cytoplasm-ER membrane (reversible) carbon dioxide --> carbon dioxide 0.002565383466644083 +r_3527_REV CO2 transport, cytoplasm-ER membrane (reversible) carbon dioxide --> carbon dioxide 0.003879003378584339 r_3528 coenzyme A transport, cytoplasm-ER membrane coenzyme A --> coenzyme A 0.0 -r_3528_REV coenzyme A transport, cytoplasm-ER membrane (reversible) coenzyme A --> coenzyme A 0.018169032940237775 -r_3529 NADPH transport, cytoplasm-ER membrane NADPH --> NADPH 0.005130766933288165 +r_3528_REV coenzyme A transport, cytoplasm-ER membrane (reversible) coenzyme A --> coenzyme A 0.019099266993774882 +r_3529 NADPH transport, cytoplasm-ER membrane NADPH --> NADPH 0.007758006757168678 r_3529_REV NADPH transport, cytoplasm-ER membrane (reversible) NADPH --> NADPH 0.0 r_3530 NADP(+) transport, cytoplasm-ER membrane NADP(+) --> NADP(+) 0.0 -r_3530_REV NADP(+) transport, cytoplasm-ER membrane (reversible) NADP(+) --> NADP(+) 0.005130766933288165 -r_3531 O2 transport, cytoplasm-ER membrane oxygen --> oxygen 0.012979638958959813 +r_3530_REV NADP(+) transport, cytoplasm-ER membrane (reversible) NADP(+) --> NADP(+) 0.007758006757168678 +r_3531 O2 transport, cytoplasm-ER membrane oxygen --> oxygen 0.01257893269764528 r_3531_REV O2 transport, cytoplasm-ER membrane (reversible) oxygen --> oxygen 0.0 -r_3532 NADH transport, cytoplasm-ER membrane NADH --> NADH 0.02415350099089217 +r_3532 NADH transport, cytoplasm-ER membrane NADH --> NADH 0.02364216243223177 r_3532_REV NADH transport, cytoplasm-ER membrane (reversible) NADH --> NADH 0.0 r_3533 NAD transport, cytoplasm-ER membrane NAD --> NAD 0.0 -r_3533_REV NAD transport, cytoplasm-ER membrane (reversible) NAD --> NAD 0.02415350099089217 -r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.006677262961478941 +r_3533_REV NAD transport, cytoplasm-ER membrane (reversible) NAD --> NAD 0.02364216243223177 +r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.006677262961452116 r_3534_REV glycerol 3-phosphate transport, cytoplasm-ER membrane (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3535 dihydroxyacetone phosphate transport, cytoplasm-ER membrane dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3535_REV dihydroxyacetone phosphate transport, cytoplasm-ER membrane (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3536 diphosphate transport, cytoplasm-ER membrane diphosphate --> diphosphate 0.0 -r_3536_REV diphosphate transport, cytoplasm-ER membrane (reversible) diphosphate --> diphosphate 0.0063193470566687195 +r_3536_REV diphosphate transport, cytoplasm-ER membrane (reversible) diphosphate --> diphosphate 0.0061186482919766815 r_3537 phosphate transport, cytoplasm-ER membrane phosphate --> phosphate 0.0 r_3537_REV phosphate transport, cytoplasm-ER membrane (reversible) phosphate --> phosphate 0.0 -r_3538 CTP transport, cytoplasm-ER membrane CTP --> CTP 0.006118648291964476 +r_3538 CTP transport, cytoplasm-ER membrane CTP --> CTP 0.0061186482919766815 r_3538_REV CTP transport, cytoplasm-ER membrane (reversible) CTP --> CTP 0.0 r_3539 CDP transport, cytoplasm-ER membrane CDP --> CDP 0.0 r_3539_REV CDP transport, cytoplasm-ER membrane (reversible) CDP --> CDP 0.0 r_3540 CMP transport, cytoplasm-ER membrane CMP --> CMP 0.0 -r_3540_REV CMP transport, cytoplasm-ER membrane (reversible) CMP --> CMP 0.009740309790961217 +r_3540_REV CMP transport, cytoplasm-ER membrane (reversible) CMP --> CMP 0.009740309791598921 r_3541 CDP-ethanolamine transport, cytoplasm-ER membrane CDP-ethanolamine --> CDP-ethanolamine 0.0 r_3541_REV CDP-ethanolamine transport, cytoplasm-ER membrane (reversible) CDP-ethanolamine --> CDP-ethanolamine 0.0 -r_3542 CDP-choline transport, cytoplasm-ER membrane CDP-choline --> CDP-choline 0.0036216614989950545 +r_3542 CDP-choline transport, cytoplasm-ER membrane CDP-choline --> CDP-choline 0.0036216614996331946 r_3542_REV CDP-choline transport, cytoplasm-ER membrane (reversible) CDP-choline --> CDP-choline 0.0 -r_3543 ATP transport, cytoplasm-ER membrane ATP --> ATP 0.0002006987647042427 +r_3543 ATP transport, cytoplasm-ER membrane ATP --> ATP 0.0 r_3543_REV ATP transport, cytoplasm-ER membrane (reversible) ATP --> ATP 0.0 r_3544 AMP transport, cytoplasm-ER membrane AMP --> AMP 0.0 -r_3544_REV AMP transport, cytoplasm-ER membrane (reversible) AMP --> AMP 0.0002006987647042427 -r_3545 L-serine transport, cytoplasm-ER membrane 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.005292964877854527 +r_3544_REV AMP transport, cytoplasm-ER membrane (reversible) AMP --> AMP 0.0 +r_3545 L-serine transport, cytoplasm-ER membrane 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.0052929648778654815 r_3545_REV L-serine transport, cytoplasm-ER membrane (reversible) 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.0 -r_3546 myo-inositol transport, cytoplasm-ER membrane myo-inositol --> myo-inositol 0.0008256834141099491 +r_3546 myo-inositol transport, cytoplasm-ER membrane myo-inositol --> myo-inositol 0.0008256834141111996 r_3546_REV myo-inositol transport, cytoplasm-ER membrane (reversible) myo-inositol --> myo-inositol 0.0 -r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.01041810258801183 +r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.010418102588011745 r_3547_REV S-adenosyl-L-methionine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.0 r_3548 S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.0 -r_3548_REV S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.010418102588011829 +r_3548_REV S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.010418102588011745 r_3549 episterol transport, cytoplasm-ER membrane episterol --> episterol 0.0 r_3549_REV episterol transport, cytoplasm-ER membrane (reversible) episterol --> episterol 0.0 r_3550 fecosterol transport, cytoplasm-ER membrane fecosterol --> fecosterol 0.0 @@ -4712,11 +4712,11 @@ r_3551 lanosterol transport, cytoplasm-ER membrane lanosterol --> lanosterol 0.0 r_3551_REV lanosterol transport, cytoplasm-ER membrane (reversible) lanosterol --> lanosterol 0.0 r_3552 ergosterol transport, cytoplasm-ER membrane ergosterol --> ergosterol 0.0 r_3552_REV ergosterol transport, cytoplasm-ER membrane (reversible) ergosterol --> ergosterol 0.0026582900248468 -r_3553 zymosterol transport, cytoplasm-ER membrane zymosterol --> zymosterol 3.687743221822545e-05 +r_3553 zymosterol transport, cytoplasm-ER membrane zymosterol --> zymosterol 0.0 r_3553_REV zymosterol transport, cytoplasm-ER membrane (reversible) zymosterol --> zymosterol 0.0 r_3554 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3554_REV diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3555 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0013834916631328335 +r_3555 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0008362844722709414 r_3555_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3556 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3556_REV diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 @@ -4724,7 +4724,7 @@ r_3557 diglyceride (1-18:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride r_3557_REV diglyceride (1-18:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3558 diglyceride (1-16:0, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3558_REV diglyceride (1-16:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 -r_3559 diglyceride (1-16:1, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 4.4011684577832406e-05 +r_3559 diglyceride (1-16:1, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 4.4011684577832006e-05 r_3559_REV diglyceride (1-16:1, 2-18:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3560 diglyceride (1-18:0, 2-18:1) transport, cytoplasm-ER membrane diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 r_3560_REV diglyceride (1-18:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 @@ -4739,9 +4739,9 @@ r_3564_REV 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, cytoplasm- r_3565 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 r_3565_REV 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 r_3566 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0 -r_3566_REV 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0007588092315238736 +r_3566_REV 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0007588092310058544 r_3567 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 0.0 -r_3567_REV 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 6.687418258607542e-05 +r_3567_REV 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 6.687418310534513e-05 r_3568 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) 0.0 r_3568_REV 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) 0.0 r_3569 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) 0.0 @@ -4751,24 +4751,24 @@ r_3570_REV sn-glycero-3-phosphocholine transport, ER membrane-cytoplasm (reversi r_3571 hexadecanoate (n-C16:0) transport, cytoplasm-lipid particle palmitate --> palmitate 0.0 r_3571_REV hexadecanoate (n-C16:0) transport, cytoplasm-lipid particle (reversible) palmitate --> palmitate 0.0 r_3572 hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle palmitoleate --> palmitoleate 0.0 -r_3572_REV hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle (reversible) palmitoleate --> palmitoleate 0.0005472071908618926 +r_3572_REV hexadecenoate (n-C16:1) transport, cytoplasm-lipid particle (reversible) palmitoleate --> palmitoleate 0.0005933601698330152 r_3573 octadecanoate (n-C18:0) transport, cytoplasm-lipid particle stearate --> stearate 0.0 r_3573_REV octadecanoate (n-C18:0) transport, cytoplasm-lipid particle (reversible) stearate --> stearate 0.0 r_3574 octadecenoate (n-C18:1) transport, cytoplasm-lipid particle oleate --> oleate 0.0 r_3574_REV octadecenoate (n-C18:1) transport, cytoplasm-lipid particle (reversible) oleate --> oleate 0.0 r_3575 lauroyl-CoA transport, cytoplasm-lipid particle lauroyl-CoA --> lauroyl-CoA 0.0 -r_3575_REV lauroyl-CoA transport, cytoplasm-lipid particle (reversible) lauroyl-CoA --> lauroyl-CoA 0.0005365495253866761 +r_3575_REV lauroyl-CoA transport, cytoplasm-lipid particle (reversible) lauroyl-CoA --> lauroyl-CoA 0.0 r_3576 myristoyl-CoA transport, cytoplasm-lipid particle myristoyl-CoA --> myristoyl-CoA 0.0 r_3576_REV myristoyl-CoA transport, cytoplasm-lipid particle (reversible) myristoyl-CoA --> myristoyl-CoA 0.0 r_3577 palmitoyl-CoA transport, cytoplasm-lipid particle palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3577_REV palmitoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 -r_3578 palmitoleoyl-CoA transport, cytoplasm-lipid particle palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 +r_3578 palmitoleoyl-CoA transport, cytoplasm-lipid particle palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0005933601698330152 r_3578_REV palmitoleoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 -r_3579 stearoyl-CoA transport, cytoplasm-lipid particle stearoyl-CoA --> stearoyl-CoA 0.0002776698027845354 +r_3579 stearoyl-CoA transport, cytoplasm-lipid particle stearoyl-CoA --> stearoyl-CoA 0.0002776698027845477 r_3579_REV stearoyl-CoA transport, cytoplasm-lipid particle (reversible) stearoyl-CoA --> stearoyl-CoA 0.0 -r_3580 oleoyl-CoA transport, cytoplasm-lipid particle oleoyl-CoA --> oleoyl-CoA 0.0002776698027845354 +r_3580 oleoyl-CoA transport, cytoplasm-lipid particle oleoyl-CoA --> oleoyl-CoA 0.0002776698027845477 r_3580_REV oleoyl-CoA transport, cytoplasm-lipid particle (reversible) oleoyl-CoA --> oleoyl-CoA 0.0 -r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle glycerol 3-phosphate --> glycerol 3-phosphate 0.0002776698027845354 +r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle glycerol 3-phosphate --> glycerol 3-phosphate 0.0002776698027845477 r_3581_REV glycerol 3-phosphate transport, cytoplasm-lipid particle (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3582 dihydroxyacetone phosphate transport, cytoplasm-lipid particle dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3582_REV dihydroxyacetone phosphate transport, cytoplasm-lipid particle (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 @@ -4776,16 +4776,16 @@ r_3583 NADPH transport, cytoplasm-lipid particle NADPH --> NADPH 0.0 r_3583_REV NADPH transport, cytoplasm-lipid particle (reversible) NADPH --> NADPH 0.0 r_3584 NADP(+) transport, cytoplasm-lipid particle NADP(+) --> NADP(+) 0.0 r_3584_REV NADP(+) transport, cytoplasm-lipid particle (reversible) NADP(+) --> NADP(+) 0.0 -r_3585 ATP transport, cytoplasm-lipid particle ATP --> ATP 0.0005365495253866761 -r_3585_REV ATP transport, cytoplasm-lipid particle (reversible) ATP --> ATP 0.0 -r_3586 AMP transport, cytoplasm-lipid particle AMP --> AMP 0.0 -r_3586_REV AMP transport, cytoplasm-lipid particle (reversible) AMP --> AMP 0.0005365495253866761 -r_3587 diphosphate transport, cytoplasm-lipid particle diphosphate --> diphosphate 0.0 -r_3587_REV diphosphate transport, cytoplasm-lipid particle (reversible) diphosphate --> diphosphate 0.0005365495253866761 +r_3585 ATP transport, cytoplasm-lipid particle ATP --> ATP 0.0 +r_3585_REV ATP transport, cytoplasm-lipid particle (reversible) ATP --> ATP 0.0005933601698330152 +r_3586 AMP transport, cytoplasm-lipid particle AMP --> AMP 0.0005933601698330152 +r_3586_REV AMP transport, cytoplasm-lipid particle (reversible) AMP --> AMP 0.0 +r_3587 diphosphate transport, cytoplasm-lipid particle diphosphate --> diphosphate 0.0005933601698330152 +r_3587_REV diphosphate transport, cytoplasm-lipid particle (reversible) diphosphate --> diphosphate 0.0 r_3588 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3588_REV diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3589 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 -r_3589_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0005472071908618926 +r_3589_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3590 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3590_REV diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3591 diglyceride (1-18:1, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 @@ -4798,7 +4798,7 @@ r_3594 diglyceride (1-18:0, 2-18:1) transport, cytoplasm-lipid particle diglycer r_3594_REV diglyceride (1-18:0, 2-18:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 r_3595 diglyceride (1-18:1, 2-18:1) transport, cytoplasm-lipid particle diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 r_3595_REV diglyceride (1-18:1, 2-18:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 -r_3596 H2O transport, cytoplasm-lipid particle H2O --> H2O 0.0005472071908618926 +r_3596 H2O transport, cytoplasm-lipid particle H2O --> H2O 0.0 r_3596_REV H2O transport, cytoplasm-lipid particle (reversible) H2O --> H2O 0.0 r_3597 glycerol transport, lipid particle-cytoplasm glycerol --> glycerol 0.0 r_3597_REV glycerol transport, lipid particle-cytoplasm (reversible) glycerol --> glycerol 0.0 @@ -4812,10 +4812,10 @@ r_3601 ATP transport, cytoplasm-cell envelope ATP --> ATP 0.0 r_3601_REV ATP transport, cytoplasm-cell envelope (reversible) ATP --> ATP 0.0 r_3602 ADP transport, cytoplasm-cell envelope ADP --> ADP 0.0 r_3602_REV ADP transport, cytoplasm-cell envelope (reversible) ADP --> ADP 0.0 -r_3603 H+ transport, cytoplasm-cell envelope H+ --> H+ 0.00358478406677683 +r_3603 H+ transport, cytoplasm-cell envelope H+ --> H+ 0.0036216614996331946 r_3603_REV H+ transport, cytoplasm-cell envelope (reversible) H+ --> H+ 0.0 r_3604_EXP_1 H2O transport, cytoplasm-cell envelope 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 -r_3604_EXP_2 H2O transport, cytoplasm-cell envelope 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0036585389312132808 +r_3604_EXP_2 H2O transport, cytoplasm-cell envelope 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0036216614996331946 r_3604_EXP_3 H2O transport, cytoplasm-cell envelope 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_3604_REV_EXP_1 H2O transport, cytoplasm-cell envelope (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_3604_REV_EXP_2 H2O transport, cytoplasm-cell envelope (reversible) 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0 @@ -4832,7 +4832,7 @@ r_3607 1-(sn-glycero-3-phospho)-1D-myo-inositol transport, cell envelope-cytopla r_3607_REV 1-(sn-glycero-3-phospho)-1D-myo-inositol transport, cell envelope-cytoplasm (reversible) 1.6398111607082781 prot_P25346 + 1-(sn-glycero-3-phospho)-1D-myo-inositol --> 1-(sn-glycero-3-phospho)-1D-myo-inositol 0.0 r_3608 palmitate transport, cell envelope-cytoplasm palmitate --> palmitate 0.0 r_3608_REV palmitate transport, cell envelope-cytoplasm (reversible) palmitate --> palmitate 0.0 -r_3609 palmitoleate transport, cell envelope-cytoplasm palmitoleate --> palmitoleate 3.687743221822664e-05 +r_3609 palmitoleate transport, cell envelope-cytoplasm palmitoleate --> palmitoleate 0.0 r_3609_REV palmitoleate transport, cell envelope-cytoplasm (reversible) palmitoleate --> palmitoleate 0.0 r_3610 stearate transport, cell envelope-cytoplasm stearate --> stearate 0.0 r_3610_REV stearate transport, cell envelope-cytoplasm (reversible) stearate --> stearate 0.0 @@ -4938,12 +4938,12 @@ r_3660 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transpor r_3660_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) 0.0 r_3661 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 r_3661_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 -r_3662 H2O transport, cytoplasm-Golgi membrane H2O --> H2O 0.0035776498144189078 +r_3662 H2O transport, cytoplasm-Golgi membrane H2O --> H2O 0.0035776498150553626 r_3662_REV H2O transport, cytoplasm-Golgi membrane (reversible) H2O --> H2O 0.0 r_3663 phosphate transport, cytoplasm-Golgi membrane phosphate --> phosphate 0.0 -r_3663_REV phosphate transport, cytoplasm-Golgi membrane (reversible) phosphate --> phosphate 0.0035776498144189078 +r_3663_REV phosphate transport, cytoplasm-Golgi membrane (reversible) phosphate --> phosphate 0.0035776498150553626 r_3664 H+ transport, cytoplasm-Golgi membrane H+ --> H+ 0.0 -r_3664_REV H+ transport, cytoplasm-Golgi membrane (reversible) H+ --> H+ 0.0071552996288378155 +r_3664_REV H+ transport, cytoplasm-Golgi membrane (reversible) H+ --> H+ 0.007155299630110725 r_3665 carbon dioxide transport, cytoplasm-Golgi membrane carbon dioxide --> carbon dioxide 0.0 r_3665_REV carbon dioxide transport, cytoplasm-Golgi membrane (reversible) carbon dioxide --> carbon dioxide 0.0 r_3666 ATP transport, cytoplasm-Golgi membrane ATP --> ATP 0.0 @@ -4953,14 +4953,14 @@ r_3667_REV ADP transport, cytoplasm-Golgi membrane (reversible) ADP --> ADP 0.0 r_3668 H2O transport, cytoplasm-mitochondrial membrane H2O --> H2O 0.0017605923136975467 r_3668_REV H2O transport, cytoplasm-mitochondrial membrane (reversible) H2O --> H2O 0.0 r_3669 carbon dioxide transport, cytoplasm-mitochondrial membrane carbon dioxide --> carbon dioxide 0.0 -r_3669_REV carbon dioxide transport, cytoplasm-mitochondrial membrane (reversible) carbon dioxide --> carbon dioxide 0.004479956612996443 +r_3669_REV carbon dioxide transport, cytoplasm-mitochondrial membrane (reversible) carbon dioxide --> carbon dioxide 0.004479956612996414 r_3670 palmitoleoyl-CoA transport, cytoplasm-mitochondrial membrane palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3670_REV palmitoleoyl-CoA transport, cytoplasm-mitochondrial membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3671 oleoyl-CoA transport, cytoplasm-mitochondrial membrane oleoyl-CoA --> oleoyl-CoA 0.0 r_3671_REV oleoyl-CoA transport, cytoplasm-mitochondrial membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.0 r_3672 diglyceride (1-16:0, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3672_REV diglyceride (1-16:0, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3673 diglyceride (1-16:1, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.000836284472270941 +r_3673 diglyceride (1-16:1, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0008362844722709414 r_3673_REV diglyceride (1-16:1, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3674 diglyceride (1-18:0, 2-16:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3674_REV diglyceride (1-18:0, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 @@ -4968,7 +4968,7 @@ r_3675 diglyceride (1-18:1, 2-16:1) transport, mitochondrial membrane-cytoplasm r_3675_REV diglyceride (1-18:1, 2-16:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3676 diglyceride (1-16:0, 2-18:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3676_REV diglyceride (1-16:0, 2-18:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 -r_3677 diglyceride (1-16:1, 2-18:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 4.4011684577832406e-05 +r_3677 diglyceride (1-16:1, 2-18:1) transport, mitochondrial membrane-cytoplasm diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 4.4011684577832006e-05 r_3677_REV diglyceride (1-16:1, 2-18:1) transport, mitochondrial membrane-cytoplasm (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 r_3678 palmitate transport, mitochondrial membrane-cytoplasm palmitate --> palmitate 0.0 r_3678_REV palmitate transport, mitochondrial membrane-cytoplasm (reversible) palmitate --> palmitate 0.0 @@ -4976,7 +4976,7 @@ r_3679 stearate transport, mitochondrial membrane-cytoplasm stearate --> stearat r_3679_REV stearate transport, mitochondrial membrane-cytoplasm (reversible) stearate --> stearate 0.0 r_3680 coenzyme A transport, mitochondrial membrane-cytoplasm 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.0 r_3680_REV coenzyme A transport, mitochondrial membrane-cytoplasm (reversible) 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.0 -r_3681 laurate transport, ER membrane-lipid particle laurate --> laurate 0.0005365495253866761 +r_3681 laurate transport, ER membrane-lipid particle laurate --> laurate 0.0 r_3681_REV laurate transport, ER membrane-lipid particle (reversible) laurate --> laurate 0.0 r_3682 myristate transport, ER membrane-lipid particle myristate --> myristate 0.0 r_3682_REV myristate transport, ER membrane-lipid particle (reversible) myristate --> myristate 0.0 @@ -4994,7 +4994,7 @@ r_3688 TAG (1-16:0, 2-16:1, 3-18:1) transport, ER membrane-lipid particle trigly r_3688_REV TAG (1-16:0, 2-16:1, 3-18:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:0, 2-16:1, 3-18:1) --> triglyceride (1-16:0, 2-16:1, 3-18:1) 0.0 r_3689 TAG (1-16:1, 2-16:1, 3-16:0) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-16:0) --> triglyceride (1-16:1, 2-16:1, 3-16:0) 0.0 r_3689_REV TAG (1-16:1, 2-16:1, 3-16:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-16:0) --> triglyceride (1-16:1, 2-16:1, 3-16:0) 0.0 -r_3690 TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0005472071908618926 +r_3690 TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_3690_REV TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_3691 TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 r_3691_REV TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 @@ -5128,13 +5128,13 @@ r_3755 phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane phos r_3755_REV phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3756 phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3756_REV phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0002776698027845354 +r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0002776698027845477 r_3757_REV phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 r_3758 phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3758_REV phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3759 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 r_3759_REV phosphatidate (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 -r_3760 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.000836284472270941 +r_3760 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0008362844722709414 r_3760_REV phosphatidate (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3761 phosphatidate (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3761_REV phosphatidate (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 @@ -5142,7 +5142,7 @@ r_3762 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membr r_3762_REV phosphatidate (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3763 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3763_REV phosphatidate (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 -r_3764 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 4.4011684577832406e-05 +r_3764 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 4.4011684577832006e-05 r_3764_REV phosphatidate (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3765 phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:0, 2-16:1) --> phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 r_3765_REV phosphatidyl-L-serine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-16:1) --> phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 @@ -5150,7 +5150,7 @@ r_3766 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-mitochondri r_3766_REV phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:1, 2-16:1) --> phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0 r_3767 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 r_3767_REV phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_3768 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0034727008626706103 +r_3768 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.003472700862670582 r_3768_REV phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0 r_3769 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 r_3769_REV phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 @@ -5166,7 +5166,7 @@ r_3774 phosphatidylethanolamine (1-16:1, 2-16:1) transport, mitochondrial membra r_3774_REV phosphatidylethanolamine (1-16:1, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:1, 2-16:1) --> phosphatidylethanolamine (1-16:1, 2-16:1) 0.0 r_3775 phosphatidylethanolamine (1-18:0, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 r_3775_REV phosphatidylethanolamine (1-18:0, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_3776 phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0034727008626706103 +r_3776 phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.003472700862670582 r_3776_REV phosphatidylethanolamine (1-18:1, 2-16:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0 r_3777 phosphatidylethanolamine (1-16:0, 2-18:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_3777_REV phosphatidylethanolamine (1-16:0, 2-18:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 @@ -5176,24 +5176,24 @@ r_3779 phosphatidylethanolamine (1-18:0, 2-18:1) transport, mitochondrial membra r_3779_REV phosphatidylethanolamine (1-18:0, 2-18:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:0, 2-18:1) --> phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 r_3780 phosphatidylethanolamine (1-18:1, 2-18:1) transport, mitochondrial membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-18:1) --> phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 r_3780_REV phosphatidylethanolamine (1-18:1, 2-18:1) transport, mitochondrial membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:1, 2-18:1) --> phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 -r_3781 phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:0, 2-16:1) --> phosphatidylcholine (1-16:0, 2-16:1) 0.0001489606363244446 +r_3781 phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:0, 2-16:1) --> phosphatidylcholine (1-16:0, 2-16:1) 0.00014896063696261247 r_3781_REV phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:0, 2-16:1) --> phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_3782 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0 -r_3782_REV phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0001489606363244448 +r_3782_REV phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.00014896063696261247 r_3783 phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_3783_REV phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_3784 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_3784_REV phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_3785 phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 -r_3785_REV phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0001489606363244448 -r_3786 phosphatidylcholine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:1, 2-18:1) --> phosphatidylcholine (1-16:1, 2-18:1) 0.0001489606363244448 +r_3785_REV phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.00014896063696261247 +r_3786 phosphatidylcholine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-16:1, 2-18:1) --> phosphatidylcholine (1-16:1, 2-18:1) 0.00014896063696261247 r_3786_REV phosphatidylcholine (1-16:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-16:1, 2-18:1) --> phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_3787 phosphatidylcholine (1-18:0, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:0, 2-18:1) --> phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_3787_REV phosphatidylcholine (1-18:0, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:0, 2-18:1) --> phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_3788 phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:1, 2-18:1) --> phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_3788_REV phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:1, 2-18:1) --> phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_3789 diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3789_REV diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0023944394904621595 +r_3789_REV diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.002394439491099864 r_3790 diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3790_REV diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3791 diglyceride (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 @@ -5203,12 +5203,12 @@ r_3792_REV diglyceride (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane (r r_3793 diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3793_REV diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 r_3794 diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 -r_3794_REV diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0009055405211722131 +r_3794_REV diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.000905540521170951 r_3795 diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 -r_3795_REV diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0002776698027845354 +r_3795_REV diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0002776698027845477 r_3796 diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 r_3796_REV diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 -r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0023944394904621595 +r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.002394439491099864 r_3797_REV phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 r_3798 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3798_REV phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 @@ -5218,9 +5218,9 @@ r_3800 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane phos r_3800_REV phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3801 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3801_REV phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 -r_3802 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0009055405211722131 +r_3802 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.000905540521170951 r_3802_REV phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0002776698027845354 +r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0002776698027845477 r_3803_REV phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 r_3804 phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3804_REV phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 @@ -5386,11 +5386,11 @@ r_3876 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, ER membrane-ce r_3876_REV 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) transport, ER membrane-cell envelope (reversible) 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) 0.0 r_3877 phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:0, 2-16:1) --> phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_3877_REV phosphatidylcholine (1-16:0, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:0, 2-16:1) --> phosphatidylcholine (1-16:0, 2-16:1) 0.0 -r_3878 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0001489606363244448 +r_3878 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0001489606369626125 r_3878_REV phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_3879 phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_3879_REV phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 -r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0034727008626706103 +r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.003472700862670582 r_3880_REV phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_3881 phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_3881_REV phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 @@ -5438,11 +5438,11 @@ r_3902 cerotic acid transport, cell envelope-ER membrane cerotic acid --> ceroti r_3902_REV cerotic acid transport, cell envelope-ER membrane (reversible) cerotic acid --> cerotic acid 0.0 r_3903 phosphatidate (1-16:0, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 r_3903_REV phosphatidate (1-16:0, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 -r_3904 phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0001489606363244448 +r_3904 phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0001489606369626125 r_3904_REV phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3905 phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3905_REV phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 -r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0034727008626706103 +r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.003472700862670582 r_3906_REV phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3907 phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3907_REV phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 @@ -5484,7 +5484,7 @@ r_3925 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) transpor r_3925_REV 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) transport, cell envelope-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) 0.0 r_3926 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) transport, cell envelope-ER membrane 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) 0.0 r_3926_REV 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) transport, cell envelope-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) 0.0 -r_3927 zymosteryl palmitoleate transport, ER membrane-cell envelope zymosteryl palmitoleate --> zymosteryl palmitoleate 3.687743221822545e-05 +r_3927 zymosteryl palmitoleate transport, ER membrane-cell envelope zymosteryl palmitoleate --> zymosteryl palmitoleate 0.0 r_3927_REV zymosteryl palmitoleate transport, ER membrane-cell envelope (reversible) zymosteryl palmitoleate --> zymosteryl palmitoleate 0.0 r_3928 zymosteryl oleate transport, ER membrane-cell envelope zymosteryl oleate --> zymosteryl oleate 0.0 r_3928_REV zymosteryl oleate transport, ER membrane-cell envelope (reversible) zymosteryl oleate --> zymosteryl oleate 0.0 @@ -5561,8 +5561,8 @@ r_3963 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) [cytoplasm] SLIME rxn 1-p r_3964 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) --> 0.807012462 1-phosphatidyl-1D-myo-inositol backbone + 0.508826 C16:1 chain 0.0 r_3965 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_3966 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_3967 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0007588092315238736 -r_3968 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 6.687418258607542e-05 +r_3967 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0007588092310058544 +r_3968 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 6.687418310534513e-05 r_3969 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> 0.865135862 1-phosphatidyl-1D-myo-inositol backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_3970 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> 0.863119982 1-phosphatidyl-1D-myo-inositol backbone + 0.56493352 C18:1 chain 0.0 r_3971 ergosteryl palmitoleate [endoplasmic reticulum membrane] SLIME rxn ergosteryl palmitoleate --> 0.63305448 ergosterol ester backbone + 0.254413 C16:1 chain 0.0 @@ -5583,13 +5583,13 @@ r_3985 phosphatidyl-L-serine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] S r_3986 phosphatidyl-L-serine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:1, 2-18:1) --> 0.788055822 phosphatidyl-L-serine backbone + 0.56493352 C18:1 chain 0.0 r_3987 phosphatidyl-L-serine transport, ER membrane-cytoplasm phosphatidyl-L-serine backbone --> phosphatidyl-L-serine backbone 0.000595080018974841 r_3987_REV phosphatidyl-L-serine transport, ER membrane-cytoplasm (reversible) phosphatidyl-L-serine backbone --> phosphatidyl-L-serine backbone 0.0 -r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-16:1) --> 0.732035022 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.002245478854137715 +r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-16:1) --> 0.732035022 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0022454788541372518 r_3989 phosphatidylcholine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-16:1) --> 0.730019142 phosphatidylcholine backbone + 0.508826 C16:1 chain 0.0 r_3990 phosphatidylcholine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-16:1) --> 0.744089382 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_3991 phosphatidylcholine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-16:1) --> 0.742073502 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-18:1) --> 0.760088782 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0001489606363244448 -r_3993 phosphatidylcholine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-18:1) --> 0.758072902 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0008005915694256007 -r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-18:1) --> 0.772143142 phosphatidylcholine backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0002776698027845354 +r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-18:1) --> 0.760088782 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.00014896063696261247 +r_3993 phosphatidylcholine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-18:1) --> 0.758072902 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0008005915687861705 +r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-18:1) --> 0.772143142 phosphatidylcholine backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0002776698027845477 r_3995 phosphatidylcholine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-18:1) --> 0.770127262 phosphatidylcholine backbone + 0.56493352 C18:1 chain 0.0 r_3996 phosphatidylcholine transport, ER membrane-cytoplasm phosphatidylcholine backbone --> phosphatidylcholine backbone 0.0025783000793308 r_3996_REV phosphatidylcholine transport, ER membrane-cytoplasm (reversible) phosphatidylcholine backbone --> phosphatidylcholine backbone 0.0 @@ -5613,7 +5613,7 @@ r_4012 triglyceride (1-18:1, 2-16:1, 3-16:0) [endoplasmic reticulum membrane] SL r_4013 triglyceride (1-18:1, 2-18:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-16:0) --> 0.85941128 triglyceride backbone + 0.25642888 C16:0 chain + 0.56493352 C18:1 chain 0.0 r_4014 triglyceride (1-16:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-16:1) --> 0.80330376 triglyceride backbone + 0.25642888 C16:0 chain + 0.508826 C16:1 chain 0.0 r_4015 triglyceride (1-16:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-18:1, 3-16:1) --> 0.83135752 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-16:1) --> 0.80128788 triglyceride backbone + 0.763239 C16:1 chain 0.00031730953913845154 +r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-16:1) --> 0.80128788 triglyceride backbone + 0.763239 C16:1 chain 0.00031730953913846434 r_4017 triglyceride (1-16:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-18:1, 3-16:1) --> 0.82934164 triglyceride backbone + 0.508826 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_4018 triglyceride (1-18:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-16:1, 3-16:1) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_4019 triglyceride (1-18:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-18:1, 3-16:1) --> 0.85941128 triglyceride backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5621,7 +5621,7 @@ r_4020 triglyceride (1-18:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SL r_4021 triglyceride (1-18:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-16:1) --> 0.8573954 triglyceride backbone + 0.254413 C16:1 chain + 0.56493352 C18:1 chain 0.0 r_4022 triglyceride (1-16:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-18:0) --> 0.8333734 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_4023 triglyceride (1-16:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-18:1, 3-18:0) --> 0.86142716 triglyceride backbone + 0.25642888 C16:0 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 -r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-18:0) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0005189749331324894 +r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-18:0) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0005189749331324772 r_4025 triglyceride (1-16:1, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-18:1, 3-18:0) --> 0.85941128 triglyceride backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_4026 triglyceride (1-18:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-16:1, 3-18:0) --> 0.86142716 triglyceride backbone + 0.254413 C16:1 chain + 0.56896528 C18:0 chain 0.0 r_4027 triglyceride (1-18:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-18:1, 3-18:0) --> 0.88948092 triglyceride backbone + 0.56896528 C18:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5637,7 +5637,7 @@ r_4036 triglyceride (1-18:1, 2-16:1, 3-18:1) [endoplasmic reticulum membrane] SL r_4037 triglyceride (1-18:1, 2-18:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-18:1) --> 0.88544916 triglyceride backbone + 0.84740028 C18:1 chain 0.0 r_4038 triglyceride transport, ER membrane-cytoplasm triglyceride backbone --> triglyceride backbone 0.0006857100012712191 r_4038_REV triglyceride transport, ER membrane-cytoplasm (reversible) triglyceride backbone --> triglyceride backbone 0.0 -r_4039 succinyl-CoA:acetate CoA transferase 2.0420759036703515 prot_P32316 + acetate + succinyl-CoA --> acetyl-CoA + succinate 1.483945717424315 +r_4039 succinyl-CoA:acetate CoA transferase 2.0420759036703515 prot_P32316 + acetate + succinyl-CoA --> acetyl-CoA + succinate 0.07150891045205127 r_4039_REV succinyl-CoA:acetate CoA transferase (reversible) 2.24640342822161 prot_P32316 + acetyl-CoA + succinate --> acetate + succinyl-CoA 0.0 r_4040 heme a transport heme a --> heme a 0.0 r_4040_REV heme a transport (reversible) heme a --> heme a 0.0 @@ -5646,7 +5646,7 @@ r_4042 raffinose invertase 0.3719983416252073 prot_standard + H2O + raffinose -- r_4043 raffinose exchange raffinose --> 0.0 r_4044 melibiose exchange melibiose --> 0.0 r_4045 uridine hydrolase 0.5272222222222223 prot_Q04179 + H2O + uridine --> D-ribose + uracil 0.0 -r_4046 non-growth associated maintenance reaction ATP + H2O --> ADP + H+ + phosphate 8.226327078419569 +r_4046 non-growth associated maintenance reaction ATP + H2O --> ADP + H+ + phosphate 9.430217473538946 r_4047 protein pseudoreaction 0.347736630768556 Ala-tRNA(Ala) + 0.194296205196944 Arg-tRNA(Arg) + 0.191468067207859 Asn-tRNA(Asn) + 0.240359946744132 Asp-tRNA(Asp) + 0.0375594996568427 Cys-tRNA(Cys) + 0.141160332291015 Gln-tRNA(Gln) + 0.296487312016288 Glu-tRNA(Glu) + 0.283748983111195 Gly-tRNA(Gly) + 0.08356708763266 His-tRNA(His) + 0.265490320174191 Ile-tRNA(Ile) + 0.362523293945085 Leu-tRNA(Leu) + 0.32939964005654 Lys-tRNA(Lys) + 0.0814974664727417 Met-tRNA(Met) + 0.166795958026717 Phe-tRNA(Phe) + 0.179821149401597 Pro-tRNA(Pro) + 0.277725658983052 Ser-tRNA(Ser) + 0.235173028298401 Thr-tRNA(Thr) + 0.0385698144584582 Trp-tRNA(Trp) + 0.123025660792855 Tyr-tRNA(Tyr) + 0.31460454977486 Val-tRNA(Val) --> 4.17785919150305 H+ + 0.347736630768556 tRNA(Ala) + 0.194296205196944 tRNA(Arg) + 0.191468067207859 tRNA(Asn) + 0.240359946744132 tRNA(Asp) + 0.0375594996568427 tRNA(Cys) + 0.141160332291015 tRNA(Gln) + 0.296487312016288 tRNA(Glu) + 0.283748983111195 tRNA(Gly) + 0.08356708763266 tRNA(His) + 0.265490320174191 tRNA(Ile) + 0.362523293945085 tRNA(Leu) + 0.32939964005654 tRNA(Lys) + 0.0814974664727417 tRNA(Met) + 0.166795958026717 tRNA(Phe) + 0.179821149401597 tRNA(Pro) + 0.277725658983052 tRNA(Ser) + 0.235173028298401 tRNA(Thr) + 0.0385698144584582 tRNA(Trp) + 0.123025660792855 tRNA(Tyr) + 0.31460454977486 tRNA(Val) + protein 0.1 r_4048 carbohydrate pseudoreaction 0.73914 (1->3)-beta-D-glucan + 0.24696 (1->6)-beta-D-glucan + 0.02361 chitin + 0.35689 glycogen + 0.70204 mannan + 0.13655 trehalose --> carbohydrate 0.1 r_4049 RNA pseudoreaction 0.0445348319234424 AMP + 0.043276239184487 CMP + 0.0445348319234424 GMP + 0.380675999881061 H+ + 0.0579920969091588 UMP --> RNA 0.1 @@ -5904,7 +5904,7 @@ r_4195_EXP_1 Zinc transporter YKE4 1.2208333333333334 prot_P20107 + Zn(2+) --> Z r_4195_EXP_2 Zinc transporter YKE4 1.2160353535353536 prot_P32798 + Zn(2+) --> Zn(2+) 0.0 r_4195_REV_EXP_1 Zinc transporter YKE4 (reversible) 1.2208333333333334 prot_P20107 + Zn(2+) --> Zn(2+) 0.0 r_4195_REV_EXP_2 Zinc transporter YKE4 (reversible) 1.2160353535353536 prot_P32798 + Zn(2+) --> Zn(2+) 0.0 -r_4196_EXP_1 NADH:ferricytochrome-b5 oxidoreductase 0.007953030303030304 prot_P38626 + NADH + 2.0 ferricytochrome b5 --> H+ + NAD + 2.0 ferrocytochrome b5 0.011173862031932357 +r_4196_EXP_1 NADH:ferricytochrome-b5 oxidoreductase 0.007953030303030304 prot_P38626 + NADH + 2.0 ferricytochrome b5 --> H+ + NAD + 2.0 ferrocytochrome b5 0.011063229734586491 r_4196_EXP_2 NADH:ferricytochrome-b5 oxidoreductase 0.008910858585858586 prot_Q12746 + NADH + 2.0 ferricytochrome b5 --> H+ + NAD + 2.0 ferrocytochrome b5 0.0 r_4196_REV_EXP_1 NADH:ferricytochrome-b5 oxidoreductase (reversible) 0.02916111111111111 prot_P38626 + H+ + NAD + 2.0 ferrocytochrome b5 --> NADH + 2.0 ferricytochrome b5 0.0 r_4196_REV_EXP_2 NADH:ferricytochrome-b5 oxidoreductase (reversible) 0.032673148148148146 prot_Q12746 + H+ + NAD + 2.0 ferrocytochrome b5 --> NADH + 2.0 ferricytochrome b5 0.0 @@ -5944,7 +5944,7 @@ r_4212_REV_EXP_2 D-ribulose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5 r_4214 L-cysteinylglycine dipeptidase 0.44291358035466905 prot_P43616 + H2O + L-cysteinylglycine --> L-cysteine + L-glycine 0.0 r_4214_REV L-cysteinylglycine dipeptidase (reversible) 1.1513279129330525 prot_P43616 + L-cysteine + L-glycine --> H2O + L-cysteinylglycine 0.0 r_4216 riboflavin-5-phosphate phosphohydrolase 2.307741115456161 prot_P52290 + FMN + H2O --> phosphate + riboflavin 0.0 -r_4216_REV riboflavin-5-phosphate phosphohydrolase (reversible) 1.7221699633075207 prot_P52290 + phosphate + riboflavin --> FMN + H2O 9.99999974737875e-07 +r_4216_REV riboflavin-5-phosphate phosphohydrolase (reversible) 1.7221699633075207 prot_P52290 + phosphate + riboflavin --> FMN + H2O 9.999999747378697e-07 r_4217 Fe(II):oxygen oxidoreductase; Fe2+:oxygen oxidoreductase 2.4608585858585856 prot_Q07540 + 4.0 H+ + 4.0 iron(2+) + oxygen --> 2.0 H2O + 4.0 iron(3+) 0.0 r_4217_REV Fe(II):oxygen oxidoreductase; Fe2+:oxygen oxidoreductase (reversible) 2.4608585858585856 prot_Q07540 + 2.0 H2O + 4.0 iron(3+) --> 4.0 H+ + 4.0 iron(2+) + oxygen 0.0 r_4218 D-aminoacyl-tRNA deacylase (DTD) (EC 3.1.1.96) (D-tyrosyl-tRNA(Tyr) deacylase) (Gly-tRNA(Ala) deacylase) (EC 3.1.1.-) 0.015505555555555555 prot_Q07648 + H2O + Glycyl-tRNA(Ala) --> H+ + L-glycine + tRNA(Ala) 0.0 @@ -6127,7 +6127,7 @@ r_4328_REV UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase (reversible) r_4329 Putative sulfate transporter YPR003C 2.105656565656566 prot_P53394 + sulphate --> sulphate 0.0 r_4329_REV Putative sulfate transporter YPR003C (reversible) 2.105656565656566 prot_P53394 + sulphate --> sulphate 0.0 r_4330 Pyridoxine:NADP+ 4-oxidoreductase 28.426997929479914 prot_Q06494 + NADP(+) + pyridoxine --> H+ + NADPH + pyridoxal 0.0 -r_4330_REV Pyridoxine:NADP+ 4-oxidoreductase (reversible) 7.099034416207216 prot_Q06494 + H+ + NADPH + pyridoxal --> NADP(+) + pyridoxine 0.0032230999986985398 +r_4330_REV Pyridoxine:NADP+ 4-oxidoreductase (reversible) 7.099034416207216 prot_Q06494 + H+ + NADPH + pyridoxal --> NADP(+) + pyridoxine 0.0 r_4331_EXP_1 [1,4-(N-Acetyl-beta-D-glucosaminyl)]n glycanohydrolase 0.19676092339643741 prot_Q06350 + chitin + H2O --> N-Acetyl-D-glucosamine 0.0 r_4331_EXP_2 [1,4-(N-Acetyl-beta-D-glucosaminyl)]n glycanohydrolase 0.1964181111377373 prot_P29029 + chitin + H2O --> N-Acetyl-D-glucosamine 0.0 r_4331_REV_EXP_1 [1,4-(N-Acetyl-beta-D-glucosaminyl)]n glycanohydrolase (reversible) 12.632051282051282 prot_Q06350 + N-Acetyl-D-glucosamine --> chitin + H2O 0.0 @@ -6136,8 +6136,8 @@ r_4332 Protein PNS1 (pH nine-sensitive protein 1) 4.890140948879145 prot_Q12412 r_4332_REV Protein PNS1 (pH nine-sensitive protein 1) (reversible) 4.890140948879145 prot_Q12412 + choline --> choline 0.0 r_4333_EXP_1 Polyphosphate phosphohydrolase 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4333_EXP_2 Polyphosphate phosphohydrolase 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 -r_4333_REV_EXP_1 Polyphosphate phosphohydrolase (reversible) 0.008073655913978494 prot_P38698 + H+ + 2.0 phosphate --> H2O + polyphosphate 5.419824394762779 -r_4333_REV_EXP_2 Polyphosphate phosphohydrolase (reversible) 0.014040143369175627 prot_Q04119 + H+ + 2.0 phosphate --> H2O + polyphosphate 1.2202670507866937 +r_4333_REV_EXP_1 Polyphosphate phosphohydrolase (reversible) 0.008073655913978494 prot_P38698 + H+ + 2.0 phosphate --> H2O + polyphosphate 7.247562191496465 +r_4333_REV_EXP_2 Polyphosphate phosphohydrolase (reversible) 0.014040143369175627 prot_Q04119 + H+ + 2.0 phosphate --> H2O + polyphosphate 0.0 r_4334 Copper-transporting ATPase (EC 3.6.3.54) (Cu(2+)-ATPase) 117.33867521367522 prot_P38995 + ATP + H2O + Cu2(+) --> ADP + H+ + phosphate + Cu2(+) 0.0 r_4335 Endopolyphosphatase (EC 3.6.1.10) (Deoxyadenosine triphosphate phosphohydrolase) (dATP phosphohydrolase) (EC 3.6.1.-) (Exopolyphosphatase) (EC 3.6.1.11) (Phosphate metabolism protein 5) 0.014040143369175627 prot_Q04119 + dATP + H2O --> dADP + H+ + phosphate 0.0 r_4336 Monoamide of a dicarboxylic acid amidohydrolase 0.12436573437261195 prot_P49954 + H2O + 2-Oxoglutaramate --> 2-oxoglutarate + ammonium 0.0 @@ -6327,7 +6327,7 @@ r_4445 3-Phospho-D-glycerate transport in/out via proton symport H+ + 3-phosphon r_4446 D-glucose 1-phosphate transport via diffusion D-glucose 1-phosphate --> D-glucose 1-phosphate 0.0 r_4446_REV D-glucose 1-phosphate transport via diffusion (reversible) D-glucose 1-phosphate --> D-glucose 1-phosphate 0.0 r_4447 carbamoyl phosphate nuclear transport via diffusion carbamoyl phosphate --> carbamoyl phosphate 0.0 -r_4447_REV carbamoyl phosphate nuclear transport via diffusion (reversible) carbamoyl phosphate --> carbamoyl phosphate 0.14323705675437173 +r_4447_REV carbamoyl phosphate nuclear transport via diffusion (reversible) carbamoyl phosphate --> carbamoyl phosphate 0.167129402150773 r_4448_EXP_1 Met-Ala transport via proton symport (extracellular to cytosol) 5.223723784843915 prot_P15365 + H+ + Met-Ala --> H+ + Met-Ala 0.0 r_4448_EXP_2 Met-Ala transport via proton symport (extracellular to cytosol) 2.451694371295385 prot_P32901 + H+ + Met-Ala --> H+ + Met-Ala 0.0 r_4449 Met-Ala transport via proton symport (cytosol to vacuole) H+ + Met-Ala --> H+ + Met-Ala 0.0 @@ -6383,7 +6383,7 @@ r_4478_REV L-methionine S-oxide transport via diffusion (extracellular) (reversi r_4479 Gly-Asn transport via proton symport H+ + Gly-Asn --> H+ + Gly-Asn 0.0 r_4479_REV Gly-Asn transport via proton symport (reversible) H+ + Gly-Asn --> H+ + Gly-Asn 0.0 r_4480 Cysteamine transport via proton antiport H+ + cysteamine --> H+ + cysteamine 0.0 -r_4481 Hydrogen sulfide oxidation 0.6656659785008318 prot_standard + hydrogen sulfide + 2.0 oxygen --> H+ + sulphate 0.00011924916613590374 +r_4481 Hydrogen sulfide oxidation 0.6656659785008318 prot_standard + hydrogen sulfide + 2.0 oxygen --> H+ + sulphate 0.0 r_4482 L-alanine transport in via proton symport H+ + L-alanine --> H+ + L-alanine 0.0 r_4482_REV L-alanine transport in via proton symport (reversible) H+ + L-alanine --> H+ + L-alanine 0.0 r_4483 Glycine transport (vacuole) H+ + L-glycine --> H+ + L-glycine 0.0 @@ -6394,17 +6394,17 @@ r_4484_EXP_3 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropy r_4484_REV_EXP_1 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) (reversible) 0.16609504132231406 prot_P47164 + L-homocysteine + succinate --> hydrogen sulfide + O-succinyl-L-homoserine 0.0 r_4484_REV_EXP_2 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) (reversible) 11.75934135228728 prot_Q12198 + L-homocysteine + succinate --> hydrogen sulfide + O-succinyl-L-homoserine 0.0 r_4484_REV_EXP_3 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) (reversible) 0.170599173553719 prot_Q04533 + L-homocysteine + succinate --> hydrogen sulfide + O-succinyl-L-homoserine 0.0 -r_4485 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) 1.1329040404040405 prot_standard + 3-(4-hydroxyphenyl)pyruvate + oxygen --> carbon dioxide + homogentisate 0.04264204402445992 -r_4486 Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) 1.1329040404040405 prot_standard + oxygen + homogentisate --> H+ + 4-maleylacetoacetate 0.04264204402445992 -r_4487 4-Maleylacetoacetate cis-trans-isomerase 1.1329040404040405 prot_standard + 4-maleylacetoacetate --> 4-fumarylacetoacetate 0.04264204402445992 -r_4488 4-fumarylacetoacetate fumarylhydrolase 1.1329040404040405 prot_standard + H2O + 4-fumarylacetoacetate --> fumarate + H+ + acetoacetate 0.04264204402445992 +r_4485 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) 1.1329040404040405 prot_standard + 3-(4-hydroxyphenyl)pyruvate + oxygen --> carbon dioxide + homogentisate 0.0 +r_4486 Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) 1.1329040404040405 prot_standard + oxygen + homogentisate --> H+ + 4-maleylacetoacetate 0.0 +r_4487 4-Maleylacetoacetate cis-trans-isomerase 1.1329040404040405 prot_standard + 4-maleylacetoacetate --> 4-fumarylacetoacetate 0.0 +r_4488 4-fumarylacetoacetate fumarylhydrolase 1.1329040404040405 prot_standard + H2O + 4-fumarylacetoacetate --> fumarate + H+ + acetoacetate 0.0 r_4489 L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming) 1.1329040404040405 prot_standard + L-arabinitol + NAD --> H+ + NADH + L-xylulose 0.0 r_4490 Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) 1.1329040404040405 prot_standard + H+ + NADPH + L-xylulose --> NADP(+) + xylitol 0.0 r_4490_REV Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) (reversible) 1.1329040404040405 prot_standard + NADP(+) + xylitol --> H+ + NADPH + L-xylulose 0.0 r_4491 arabinose reductase (D-arabinose) 0.45405614353626883 prot_standard + D-arabinose + H+ + NADPH --> NADP(+) + D-arabinitol 0.0 r_4492 D-arabinitol:NAT 4-oxidoreductase 1.1329040404040405 prot_standard + NAD + D-arabinitol --> D-xylulose + H+ + NADH 0.0 r_4493 Acetoacetate transport via diffusion 83.31663433619322 prot_P53943 + acetoacetate --> acetoacetate 0.0 -r_4493_REV Acetoacetate transport via diffusion (reversible) 83.31663433619322 prot_P53943 + acetoacetate --> acetoacetate 0.04264204402445992 +r_4493_REV Acetoacetate transport via diffusion (reversible) 83.31663433619322 prot_P53943 + acetoacetate --> acetoacetate 0.0 r_4494 methanol exchange methanol --> 0.0 r_4495 alkaline phosphatase 0.5934259259259259 prot_standard + adenosine 2'-phosphate + H2O --> adenosine + phosphate 0.0 r_4496 Ala-Gly exchange Ala-Gly --> 0.0 @@ -6442,7 +6442,7 @@ r_4527 diphosphate exchange diphosphate --> 0.0 r_4528 triphosphate exchange triphosphate --> 0.0 r_4529 phosphoenolpyruvate exchange phosphoenolpyruvate --> 0.0 r_4530 N(omega)-phospho-L-arginine exchange N(omega)-phospho-L-arginine --> 0.0 -r_4531 carbamoyl phosphate exchange carbamoyl phosphate --> 0.14323705675437173 +r_4531 carbamoyl phosphate exchange carbamoyl phosphate --> 0.167129402150773 r_4532 O-phosphoethanolamine exchange O-phosphoethanolamine --> 0.0 r_4533 cysteamine S-phosphate exchange cysteamine S-phosphate --> 0.0 r_4534 guanosine 2'-monophosphate exchange guanosine 2'-monophosphate --> 0.0 @@ -6466,7 +6466,7 @@ r_4551 3-sulfino-L-alanine exchange 3-sulfino-L-alanine --> 0.0 r_4552 N-acetyl-L-cysteine exchange N-acetyl-L-cysteine --> 0.0 r_4553 L-cysteate exchange L-cysteate --> 0.0 r_4554 2-hydroxyethane-1-sulfonate exchange 2-hydroxyethane-1-sulfonate --> 0.0 -r_4555 acetoacetate exchange acetoacetate --> 0.04264204402445992 +r_4555 acetoacetate exchange acetoacetate --> 0.0 r_4556 N-acetyl-L-glutamate exchange N-acetyl-L-glutamate --> 0.0 r_4557 UMP exchange UMP --> 0.0 r_4558 CMP exchange CMP --> 0.0 @@ -6481,17 +6481,17 @@ r_4567 6-phosphogluconate phosphatase 0.17308256172839506 prot_standard + 6-phos r_4569 Carboxylic ester hydrolases 0.45405614353626883 prot_standard + acetate + H+ + Hydroquinone --> H2O + 4-hydroxyphenyl acetate 0.0 r_4570_EXP_1 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + NAD + 2-hydroxyglutarate --> 2-oxoglutarate + H+ + NADH 0.0 r_4570_EXP_2 phosphoglycerate dehydrogenase 0.0036935786435786434 prot_P40054 + NAD + 2-hydroxyglutarate --> 2-oxoglutarate + H+ + NADH 0.0 -r_4570_REV_EXP_1 phosphoglycerate dehydrogenase (reversible) 0.005777687480247415 prot_P40510 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.022848860416990944 +r_4570_REV_EXP_1 phosphoglycerate dehydrogenase (reversible) 0.005777687480247415 prot_P40510 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.02285813596186906 r_4570_REV_EXP_2 phosphoglycerate dehydrogenase (reversible) 0.0057782518398121815 prot_P40054 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.0 -r_4571 seed:rxn00681 1.1329040404040405 prot_standard + coenzyme A + H+ + 2-hydroxyglutarate --> glyoxylate + H2O + propionyl-CoA 0.022848860416990944 +r_4571 seed:rxn00681 1.1329040404040405 prot_standard + coenzyme A + H+ + 2-hydroxyglutarate --> glyoxylate + H2O + propionyl-CoA 0.02285813596186906 r_4571_REV seed:rxn00681 (reversible) 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + 2-hydroxyglutarate 0.0 -r_4572 beta-alanine:2-oxoglutarate aminotransferase 1.1329040404040405 prot_standard + 2-oxoglutarate + beta-alanine --> L-glutamate + 3-oxopropanoate 0.0012107510237191177 +r_4572 beta-alanine:2-oxoglutarate aminotransferase 1.1329040404040405 prot_standard + 2-oxoglutarate + beta-alanine --> L-glutamate + 3-oxopropanoate 0.001210751023719089 r_4572_REV beta-alanine:2-oxoglutarate aminotransferase (reversible) 1.1329040404040405 prot_standard + L-glutamate + 3-oxopropanoate --> 2-oxoglutarate + beta-alanine 0.0 r_4573 3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NAD + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADH 0.0 -r_4574 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NADP(+) + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADPH 0.0012107510237191177 +r_4574 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NADP(+) + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADPH 0.001210751023719089 r_4575 3-oxopropanoate carboxy-lyase 0.45405614353626883 prot_standard + H+ + 3-oxopropanoate --> acetaldehyde + carbon dioxide 0.0 -r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.048490056204063985 prot_standard + NAD + (2R,3S)-3-methylmalate --> 2-oxobutanoate + carbon dioxide + NADH 0.022773982051123572 -r_4582 malate/beta-methylmalate synthase 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + (2R,3S)-3-methylmalate 0.022773982051123572 +r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.048490056204063985 prot_standard + NAD + (2R,3S)-3-methylmalate --> 2-oxobutanoate + carbon dioxide + NADH 0.022773982051123545 +r_4582 malate/beta-methylmalate synthase 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + (2R,3S)-3-methylmalate 0.022773982051123545 r_4583 palmitoyl-CoA hydrolase 2.0068374645606704 prot_standard + H2O + trans-2,cis-9-octadecadienoyl-CoA --> coenzyme A + H+ + (9Z,12Z)-octadecadienoate 0.0 r_4584_EXP_1 long-chain-fatty-acid---CoA ligase 745.8429118773946 prot_P30624 + ATP + coenzyme A + (9Z,12Z)-octadecadienoate --> AMP + diphosphate + trans-2,cis-9-octadecadienoyl-CoA 0.0 r_4584_EXP_2 long-chain-fatty-acid---CoA ligase 799.2145593869732 prot_P39518 + ATP + coenzyme A + (9Z,12Z)-octadecadienoate --> AMP + diphosphate + trans-2,cis-9-octadecadienoyl-CoA 0.0 @@ -6530,7 +6530,7 @@ r_4606 O-phosphoethanolamine transport H+ + O-phosphoethanolamine --> H+ + O-pho r_4606_REV O-phosphoethanolamine transport (reversible) H+ + O-phosphoethanolamine --> H+ + O-phosphoethanolamine 0.0 r_4607 phosphate transport phosphate --> phosphate 0.0 r_4607_REV phosphate transport (reversible) phosphate --> phosphate 0.0 -r_4608 propionyl-CoA transport ATP + H2O + propionyl-CoA --> ADP + H+ + phosphate + propionyl-CoA 7.487836586737207e-05 +r_4608 propionyl-CoA transport ATP + H2O + propionyl-CoA --> ADP + H+ + phosphate + propionyl-CoA 8.415391074551319e-05 r_4609 UDP transport UDP --> UDP 0.0 r_4609_REV UDP transport (reversible) UDP --> UDP 0.0 r_4610 UDP transport UDP --> UDP 0.0 @@ -6621,7 +6621,7 @@ r_4651_EXP_2 pyruvate decarboxylase (aldedyde-forming) 0.11780651340996169 prot_ r_4651_EXP_3 pyruvate decarboxylase (aldedyde-forming) 0.27738351254480287 prot_P16467 + 2-oxobutanoate + H+ --> carbon dioxide + propanal 0.0 r_4652_EXP_1 aldehyde dehydrogenase (1-propanol, NAD) 14.32572298325723 prot_P38113 + H+ + NADH + propanal --> NAD + propanol 0.0 r_4652_EXP_2 aldehyde dehydrogenase (1-propanol, NAD) 15.617199391171994 prot_P32771 + H+ + NADH + propanal --> NAD + propanol 0.0 -r_4652_EXP_3 aldehyde dehydrogenase (1-propanol, NAD) 0.011373148148148148 prot_P00330 + H+ + NADH + propanal --> NAD + propanol 0.0 +r_4652_EXP_3 aldehyde dehydrogenase (1-propanol, NAD) 0.011373148148148148 prot_P00330 + H+ + NADH + propanal --> NAD + propanol 9.275546752895991e-06 r_4653_EXP_1 aldehyde dehydrogenase (1-propanol, NAD) 0.012698148148148148 prot_P10127 + H+ + NADH + propanal --> NAD + propanol 0.0 r_4653_EXP_2 aldehyde dehydrogenase (1-propanol, NAD) 15.361491628614916 prot_P07246 + H+ + NADH + propanal --> NAD + propanol 0.0 r_4654_EXP_1 aldehyde dehydrogenase (1-propanol, NADP) 1.6815384615384616 prot_P25377 + H+ + NADPH + propanal --> NADP(+) + propanol 0.0 @@ -6676,7 +6676,7 @@ r_4678_EXP_1 aldehyde dehydrogenase 0.483596214511041 prot_P47771 + H2O + NAD + r_4678_EXP_2 aldehyde dehydrogenase 0.7809503666102651 prot_P54114 + H2O + NAD + propanal --> H+ + NADH + propionate 0.0 r_4678_EXP_3 aldehyde dehydrogenase 5.830373503190885 prot_P46367 + H2O + NAD + propanal --> H+ + NADH + propionate 0.0 r_4678_REV_EXP_1 aldehyde dehydrogenase (reversible) 0.483596214511041 prot_P47771 + H+ + NADH + propionate --> H2O + NAD + propanal 0.0 -r_4678_REV_EXP_2 aldehyde dehydrogenase (reversible) 0.06410300925925926 prot_P54114 + H+ + NADH + propionate --> H2O + NAD + propanal 0.0 +r_4678_REV_EXP_2 aldehyde dehydrogenase (reversible) 0.06410300925925926 prot_P54114 + H+ + NADH + propionate --> H2O + NAD + propanal 9.275546752895991e-06 r_4678_REV_EXP_3 aldehyde dehydrogenase (reversible) 4.681477254164319 prot_P46367 + H+ + NADH + propionate --> H2O + NAD + propanal 0.0 r_4679_EXP_1 short-chain-fatty-acid-CoA ligase (propionate) 745.8429118773946 prot_P30624 + ATP + coenzyme A + propionate --> AMP + diphosphate + H+ + propionyl-CoA 0.0 r_4679_EXP_2 short-chain-fatty-acid-CoA ligase (propionate) 799.2145593869732 prot_P39518 + ATP + coenzyme A + propionate --> AMP + diphosphate + H+ + propionyl-CoA 0.0 @@ -6685,13 +6685,13 @@ r_4679_EXP_4 short-chain-fatty-acid-CoA ligase (propionate) 740.1053639846743 pr r_4679_REV_EXP_1 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 4.2393447911960855 prot_P30624 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 r_4679_REV_EXP_2 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 85.88964551313514 prot_P39518 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 r_4679_REV_EXP_3 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 57.978811271186636 prot_P39002 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 -r_4679_REV_EXP_4 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 2.7763568922936326 prot_P47912 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 +r_4679_REV_EXP_4 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 2.7763568922936326 prot_P47912 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 9.275546752895991e-06 r_4680_EXP_1 alcohol acyltransferase (propionyl-CoA) 23.194229036950972 prot_P38295 + ethanol + propionyl-CoA --> coenzyme A + ethyl propionate 0.0 -r_4680_EXP_2 alcohol acyltransferase (propionyl-CoA) 14.276408471502988 prot_Q02891 + ethanol + propionyl-CoA --> coenzyme A + ethyl propionate 0.0 +r_4680_EXP_2 alcohol acyltransferase (propionyl-CoA) 14.276408471502988 prot_Q02891 + ethanol + propionyl-CoA --> coenzyme A + ethyl propionate -1.9051427102567686e-12 r_4680_REV_EXP_1 alcohol acyltransferase (propionyl-CoA) (reversible) 2.0370798777168075 prot_P38295 + coenzyme A + ethyl propionate --> ethanol + propionyl-CoA 0.0 r_4680_REV_EXP_2 alcohol acyltransferase (propionyl-CoA) (reversible) 1.7854367520755017 prot_Q02891 + coenzyme A + ethyl propionate --> ethanol + propionyl-CoA 0.0 r_4681 propionyl-CoA transport, mitochondrial propionyl-CoA --> propionyl-CoA 0.0 -r_4681_REV propionyl-CoA transport, mitochondrial (reversible) propionyl-CoA --> propionyl-CoA 0.0 +r_4681_REV propionyl-CoA transport, mitochondrial (reversible) propionyl-CoA --> propionyl-CoA 9.275546752895991e-06 r_4682 butyryl-CoA transport, mitochondrial butanoyl-CoA --> butanoyl-CoA 0.0 r_4682_REV butyryl-CoA transport, mitochondrial (reversible) butanoyl-CoA --> butanoyl-CoA 0.0 r_4683 hexanoyl-CoA transport, mitochondrial hexanoyl-CoA --> hexanoyl-CoA 0.0 @@ -6700,7 +6700,7 @@ r_4684 octanoyl-CoA transport, mitochondrial octanoyl-CoA --> octanoyl-CoA 0.0 r_4684_REV octanoyl-CoA transport, mitochondrial (reversible) octanoyl-CoA --> octanoyl-CoA 0.0 r_4685 decanoyl-CoA transport, mitochondrial decanoyl-CoA --> decanoyl-CoA 0.0 r_4685_REV decanoyl-CoA transport, mitochondrial (reversible) decanoyl-CoA --> decanoyl-CoA 0.0 -r_4686 propionate transport, cytosol propionate --> propionate 0.0 +r_4686 propionate transport, cytosol propionate --> propionate 9.275546752895991e-06 r_4686_REV propionate transport, cytosol (reversible) propionate --> propionate 0.0 r_4687_EXP_1 alcohol acetyltransferase (tyrosol) 0.00442002285061411 prot_P53296 + acetyl-CoA + tyrosol --> coenzyme A + tyrosyl acetate 0.0 r_4687_EXP_2 alcohol acetyltransferase (tyrosol) 0.004358469008854613 prot_P40353 + acetyl-CoA + tyrosol --> coenzyme A + tyrosyl acetate 0.0 @@ -6713,15 +6713,15 @@ r_4690_EXP_3 alcohol acetyltransferase (methionol) 1.451522803795531 prot_P53208 r_4691 methionyl acetate transport methionyl acetate --> methionyl acetate 0.0 r_4692 methionyl acetate exchange methionyl acetate --> 0.0 r_4693_EXP_1 alcohol acetyltransferase (propanol) 0.00442002285061411 prot_P53296 + acetyl-CoA + propanol --> coenzyme A + propyl acetate 0.0 -r_4693_EXP_2 alcohol acetyltransferase (propanol) 0.004358469008854613 prot_P40353 + acetyl-CoA + propanol --> coenzyme A + propyl acetate 0.0 +r_4693_EXP_2 alcohol acetyltransferase (propanol) 0.004358469008854613 prot_P40353 + acetyl-CoA + propanol --> coenzyme A + propyl acetate 9.275546752895991e-06 r_4693_EXP_3 alcohol acetyltransferase (propanol) 1.451522803795531 prot_P53208 + acetyl-CoA + propanol --> coenzyme A + propyl acetate 0.0 -r_4694 propyl acetate transport propyl acetate --> propyl acetate 0.0 -r_4695 propyl acetate exchange propyl acetate --> 0.0 -r_4697 ethyl propionate transport, mitochondrial ethyl propionate --> ethyl propionate 0.0 +r_4694 propyl acetate transport propyl acetate --> propyl acetate 9.275546752895991e-06 +r_4695 propyl acetate exchange propyl acetate --> 9.275546752895991e-06 +r_4697 ethyl propionate transport, mitochondrial ethyl propionate --> ethyl propionate -1.9051427102567686e-12 r_4697_REV ethyl propionate transport, mitochondrial (reversible) ethyl propionate --> ethyl propionate 0.0 -r_4698_EXP_1 ethyl propionate transport 1.5359391245241716 prot_P53943 + ethyl propionate --> ethyl propionate 0.0 +r_4698_EXP_1 ethyl propionate transport 1.5359391245241716 prot_P53943 + ethyl propionate --> ethyl propionate -1.9051427102567686e-12 r_4698_EXP_2 ethyl propionate transport 52.43332434737383 prot_P36035 + ethyl propionate --> ethyl propionate 0.0 -r_4699 ethyl propionate exchange ethyl propionate --> 0.0 +r_4699 ethyl propionate exchange ethyl propionate --> -1.9051427102567686e-12 r_4700 hydrogen sulfide transport 1.563080808080808 prot_P40445 + hydrogen sulfide --> hydrogen sulfide 0.0 r_4701 L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming) 0.011042712066905616 prot_P43623 + H2O + L-cysteine --> ammonium + H+ + pyruvate + hydrogen sulfide 0.0 r_4701_REV L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming) (reversible) 8.086395450568679 prot_P43623 + ammonium + H+ + pyruvate + hydrogen sulfide --> H2O + L-cysteine 0.0 @@ -6760,8 +6760,8 @@ r_4721_REV ethyl-2-methylbutyrate esterase, c (reversible) 0.1481119020744172 pr r_4722 polyphosphate polymerase, c 0.6242867867867868 prot_P47075 + 2.0 ATP + H2O --> 2.0 ADP + H+ + polyphosphate 0.10083170849875056 r_4723_EXP_1 polyphosphate phosphohydrolase, v 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4723_EXP_2 polyphosphate phosphohydrolase, v 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 -r_4724_EXP_1 polyphosphate phosphohydrolase, m 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 6.740923154048223 -r_4724_EXP_2 polyphosphate phosphohydrolase, m 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 +r_4724_EXP_1 polyphosphate phosphohydrolase, m 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 6.443034475217992 +r_4724_EXP_2 polyphosphate phosphohydrolase, m 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.9053594247772242 r_4725_EXP_1 polyphosphate phosphohydrolase, n 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4725_EXP_2 polyphosphate phosphohydrolase, n 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4726 ethyl-(2S)-lactate transport ethyl (2S)-lactate --> ethyl (2S)-lactate 0.0 @@ -6793,7 +6793,7 @@ r_4742_REV ethyl-2-methylbutyrate transport (reversible) ethyl 2-methylbutyrate r_4743 ethyl-2-methylbutyrate exchange ethyl 2-methylbutyrate --> 0.0 r_4744 polyphosphate transport, v-c H+ + polyphosphate --> H+ + polyphosphate 0.10083170849875056 r_4744_REV polyphosphate transport, v-c (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 -r_4745 polyphosphate transport, c-m H+ + polyphosphate --> H+ + polyphosphate 6.740923154048223 +r_4745 polyphosphate transport, c-m H+ + polyphosphate --> H+ + polyphosphate 7.348393899995215 r_4745_REV polyphosphate transport, c-m (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4746 polyphosphate transport, c-n H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4746_REV polyphosphate transport, c-n (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 @@ -6855,7 +6855,7 @@ r_4783 oxaloacetate/sulphate antiport, mitochondrial 0.8569958862601018 prot_P32 r_4783_REV oxaloacetate/sulphate antiport, mitochondrial (reversible) 0.8569958862601018 prot_P32332 + oxaloacetate + sulphate --> oxaloacetate + sulphate 0.0 r_4784 malate/sulphate antiport, mitochondrial 0.645505273974352 prot_P32332 + (S)-malate + sulphate --> (S)-malate + sulphate 0.0 r_4784_REV malate/sulphate antiport, mitochondrial (reversible) 0.645505273974352 prot_P32332 + (S)-malate + sulphate --> (S)-malate + sulphate 0.0 -r_4785 acetate transport acetate --> acetate 0.6355843009427999 +r_4785 acetate transport acetate --> acetate 0.0 r_4786_EXP_1 ribonucleotide reductase 2.143863049095607 prot_P21524 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 r_4786_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0006000000052154061 r_4786_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 @@ -6865,57 +6865,57 @@ r_4787_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + H+ + UDP + r_4787_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 r_4787_EXP_4 ribonucleotide reductase 0.9936907838070629 prot_P09938 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 usage_prot_O13525 usage_prot_O13525 prot_pool --> prot_O13525 0.0 -usage_prot_P00044 usage_prot_P00044 prot_pool --> prot_P00044 0.1290438586620156 -usage_prot_P00045 usage_prot_P00045 prot_pool --> prot_P00045 0.03879102623699175 -usage_prot_P00127 usage_prot_P00127 prot_pool --> prot_P00127 0.19683250754577944 -usage_prot_P00128 usage_prot_P00128 prot_pool --> prot_P00128 0.16612768571618922 -usage_prot_P00163 usage_prot_P00163 prot_pool --> prot_P00163 0.49793822503439455 -usage_prot_P00175 usage_prot_P00175 prot_pool --> prot_P00175 0.000996153539417695 -usage_prot_P00330 usage_prot_P00330 prot_pool --> prot_P00330 0.022823131044741752 +usage_prot_P00044 usage_prot_P00044 prot_pool --> prot_P00044 0.07904950433537222 +usage_prot_P00045 usage_prot_P00045 prot_pool --> prot_P00045 0.0 +usage_prot_P00127 usage_prot_P00127 prot_pool --> prot_P00127 0.039936365067487246 +usage_prot_P00128 usage_prot_P00128 prot_pool --> prot_P00128 0.03370650502450899 +usage_prot_P00163 usage_prot_P00163 prot_pool --> prot_P00163 0.10102926078612871 +usage_prot_P00175 usage_prot_P00175 prot_pool --> prot_P00175 0.0 +usage_prot_P00330 usage_prot_P00330 prot_pool --> prot_P00330 0.019917142947991344 usage_prot_P00331 usage_prot_P00331 prot_pool --> prot_P00331 0.0 -usage_prot_P00358 usage_prot_P00358 prot_pool --> prot_P00358 2.403848423283835 +usage_prot_P00358 usage_prot_P00358 prot_pool --> prot_P00358 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usage_prot_P32375 prot_pool --> prot_P32375 0.0 -usage_prot_P32377 usage_prot_P32377 prot_pool --> prot_P32377 0.055889580204164194 +usage_prot_P32377 usage_prot_P32377 prot_pool --> prot_P32377 0.0553362180239249 usage_prot_P32378 usage_prot_P32378 prot_pool --> prot_P32378 0.0 usage_prot_P32383 usage_prot_P32383 prot_pool --> prot_P32383 0.0 usage_prot_P32386 usage_prot_P32386 prot_pool --> prot_P32386 0.0 -usage_prot_P32419 usage_prot_P32419 prot_pool --> prot_P32419 6.193881272390903e-07 -usage_prot_P32449 usage_prot_P32449 prot_pool --> prot_P32449 0.006886808145518908 +usage_prot_P32419 usage_prot_P32419 prot_pool --> prot_P32419 1.0057346683722018e-07 +usage_prot_P32449 usage_prot_P32449 prot_pool --> prot_P32449 0.0030275563745522874 usage_prot_P32451 usage_prot_P32451 prot_pool --> prot_P32451 0.0 usage_prot_P32452 usage_prot_P32452 prot_pool --> prot_P32452 0.00021574476169689292 usage_prot_P32459 usage_prot_P32459 prot_pool --> prot_P32459 0.0 -usage_prot_P32462 usage_prot_P32462 prot_pool --> prot_P32462 0.015622718902897164 +usage_prot_P32462 usage_prot_P32462 prot_pool --> prot_P32462 0.015468038517719962 usage_prot_P32463 usage_prot_P32463 prot_pool --> prot_P32463 0.0 usage_prot_P32465 usage_prot_P32465 prot_pool --> prot_P32465 0.0 usage_prot_P32466 usage_prot_P32466 prot_pool --> prot_P32466 4.540681069070014 usage_prot_P32467 usage_prot_P32467 prot_pool --> prot_P32467 0.0 usage_prot_P32469 usage_prot_P32469 prot_pool --> prot_P32469 0.0 -usage_prot_P32473 usage_prot_P32473 prot_pool --> prot_P32473 0.07423331253557426 -usage_prot_P32476 usage_prot_P32476 prot_pool --> prot_P32476 0.6002879186421042 -usage_prot_P32477 usage_prot_P32477 prot_pool --> prot_P32477 2.1331915821484914e-10 +usage_prot_P32473 usage_prot_P32473 prot_pool --> prot_P32473 0.5842335043294654 +usage_prot_P32476 usage_prot_P32476 prot_pool --> prot_P32476 0.5943444739030734 +usage_prot_P32477 usage_prot_P32477 prot_pool --> prot_P32477 2.13319158216116e-10 usage_prot_P32486 usage_prot_P32486 prot_pool --> prot_P32486 0.0 usage_prot_P32487 usage_prot_P32487 prot_pool --> prot_P32487 0.0 usage_prot_P32528 usage_prot_P32528 prot_pool --> prot_P32528 0.0 usage_prot_P32563 usage_prot_P32563 prot_pool --> prot_P32563 0.0 usage_prot_P32567 usage_prot_P32567 prot_pool --> prot_P32567 0.0 -usage_prot_P32573 usage_prot_P32573 prot_pool --> prot_P32573 0.0 +usage_prot_P32573 usage_prot_P32573 prot_pool --> prot_P32573 0.0007100266837130259 usage_prot_P32579 usage_prot_P32579 prot_pool --> prot_P32579 0.0 -usage_prot_P32582 usage_prot_P32582 prot_pool --> prot_P32582 0.0027323753128140585 +usage_prot_P32582 usage_prot_P32582 prot_pool --> prot_P32582 0.0027323753128140785 usage_prot_P32603 usage_prot_P32603 prot_pool --> prot_P32603 0.0 usage_prot_P32604 usage_prot_P32604 prot_pool --> prot_P32604 0.0 usage_prot_P32610 usage_prot_P32610 prot_pool --> prot_P32610 0.0 @@ -7288,19 +7288,19 @@ usage_prot_P32642 usage_prot_P32642 prot_pool --> prot_P32642 0.0 usage_prot_P32643 usage_prot_P32643 prot_pool --> prot_P32643 0.0 usage_prot_P32656 usage_prot_P32656 prot_pool --> prot_P32656 0.0 usage_prot_P32771 usage_prot_P32771 prot_pool --> prot_P32771 0.0 -usage_prot_P32784 usage_prot_P32784 prot_pool --> prot_P32784 0.7543571716095807 +usage_prot_P32784 usage_prot_P32784 prot_pool --> prot_P32784 0.7543571716042168 usage_prot_P32785 usage_prot_P32785 prot_pool --> prot_P32785 0.0 usage_prot_P32791 usage_prot_P32791 prot_pool --> prot_P32791 0.0 -usage_prot_P32796 usage_prot_P32796 prot_pool --> prot_P32796 0.001312644527219678 +usage_prot_P32796 usage_prot_P32796 prot_pool --> prot_P32796 0.0002259330995483732 usage_prot_P32798 usage_prot_P32798 prot_pool --> prot_P32798 0.0 -usage_prot_P32799 usage_prot_P32799 prot_pool --> prot_P32799 0.03405563235615804 +usage_prot_P32799 usage_prot_P32799 prot_pool --> prot_P32799 0.03125195804099686 usage_prot_P32804 usage_prot_P32804 prot_pool --> prot_P32804 7.854377686321225e-05 usage_prot_P32837 usage_prot_P32837 prot_pool --> prot_P32837 0.0 usage_prot_P32842 usage_prot_P32842 prot_pool --> prot_P32842 0.0 usage_prot_P32861 usage_prot_P32861 prot_pool --> prot_P32861 0.0 usage_prot_P32874 usage_prot_P32874 prot_pool --> prot_P32874 0.0 -usage_prot_P32891 usage_prot_P32891 prot_pool --> prot_P32891 0.0 -usage_prot_P32895 usage_prot_P32895 prot_pool --> prot_P32895 0.005390169784514892 +usage_prot_P32891 usage_prot_P32891 prot_pool --> prot_P32891 0.04565462891219134 +usage_prot_P32895 usage_prot_P32895 prot_pool --> prot_P32895 0.0053901697845159385 usage_prot_P32901 usage_prot_P32901 prot_pool --> prot_P32901 0.0 usage_prot_P32903 usage_prot_P32903 prot_pool --> prot_P32903 0.0 usage_prot_P32906 usage_prot_P32906 prot_pool --> prot_P32906 0.0 @@ -7310,13 +7310,13 @@ usage_prot_P33312 usage_prot_P33312 prot_pool --> prot_P33312 5.311659714204637e usage_prot_P33315 usage_prot_P33315 prot_pool --> prot_P33315 0.0 usage_prot_P33317 usage_prot_P33317 prot_pool 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usage_prot_P33775 usage_prot_P33775 prot_pool --> prot_P33775 0.0 usage_prot_P33893 usage_prot_P33893 prot_pool --> prot_P33893 0.0 usage_prot_P34163 usage_prot_P34163 prot_pool --> prot_P34163 0.0 usage_prot_P34227 usage_prot_P34227 prot_pool --> prot_P34227 0.0 -usage_prot_P34230 usage_prot_P34230 prot_pool --> prot_P34230 0.1547494284587876 +usage_prot_P34230 usage_prot_P34230 prot_pool --> prot_P34230 0.01640115233655608 usage_prot_P34756 usage_prot_P34756 prot_pool --> prot_P34756 0.0 usage_prot_P35172 usage_prot_P35172 prot_pool --> prot_P35172 0.0 usage_prot_P35196 usage_prot_P35196 prot_pool --> prot_P35196 0.0 @@ -7335,23 +7335,23 @@ usage_prot_P35731 usage_prot_P35731 prot_pool --> prot_P35731 0.0 usage_prot_P35842 usage_prot_P35842 prot_pool --> prot_P35842 0.0 usage_prot_P36001 usage_prot_P36001 prot_pool --> prot_P36001 0.0 usage_prot_P36007 usage_prot_P36007 prot_pool --> prot_P36007 0.0 -usage_prot_P36010 usage_prot_P36010 prot_pool --> prot_P36010 0.004269657328820411 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usage_prot_P36076 prot_pool --> prot_P36076 0.00011872816473937789 usage_prot_P36088 usage_prot_P36088 prot_pool --> prot_P36088 0.0 usage_prot_P36107 usage_prot_P36107 prot_pool --> prot_P36107 0.0 -usage_prot_P36126 usage_prot_P36126 prot_pool --> prot_P36126 4.909463967012713e-05 +usage_prot_P36126 usage_prot_P36126 prot_pool --> prot_P36126 4.909463967877765e-05 usage_prot_P36136 usage_prot_P36136 prot_pool --> prot_P36136 0.0 usage_prot_P36143 usage_prot_P36143 prot_pool --> prot_P36143 0.0 -usage_prot_P36148 usage_prot_P36148 prot_pool --> prot_P36148 0.027107482089066832 +usage_prot_P36148 usage_prot_P36148 prot_pool --> prot_P36148 0.027107482089068033 usage_prot_P36150 usage_prot_P36150 prot_pool --> prot_P36150 0.0 usage_prot_P36156 usage_prot_P36156 prot_pool --> prot_P36156 0.0 usage_prot_P36165 usage_prot_P36165 prot_pool --> prot_P36165 0.0 @@ -7359,57 +7359,57 @@ usage_prot_P36421 usage_prot_P36421 prot_pool --> prot_P36421 0.0327028356769412 usage_prot_P36973 usage_prot_P36973 prot_pool --> prot_P36973 0.0 usage_prot_P37012 usage_prot_P37012 prot_pool --> prot_P37012 0.012160017659397906 usage_prot_P37020 usage_prot_P37020 prot_pool --> prot_P37020 0.0 -usage_prot_P37254 usage_prot_P37254 prot_pool --> prot_P37254 0.009172695793061679 -usage_prot_P37291 usage_prot_P37291 prot_pool --> prot_P37291 0.011033576268077574 +usage_prot_P37254 usage_prot_P37254 prot_pool --> prot_P37254 0.009172695793224815 +usage_prot_P37291 usage_prot_P37291 prot_pool --> prot_P37291 0.011034412060506068 usage_prot_P37292 usage_prot_P37292 prot_pool --> prot_P37292 0.0 usage_prot_P37296 usage_prot_P37296 prot_pool --> prot_P37296 0.0 usage_prot_P37297 usage_prot_P37297 prot_pool --> prot_P37297 0.0 -usage_prot_P37298 usage_prot_P37298 prot_pool --> prot_P37298 0.011380394958080605 -usage_prot_P37299 usage_prot_P37299 prot_pool --> prot_P37299 0.09801134248947573 +usage_prot_P37298 usage_prot_P37298 prot_pool --> prot_P37298 0.0 +usage_prot_P37299 usage_prot_P37299 prot_pool --> prot_P37299 0.01988602799008622 usage_prot_P37303 usage_prot_P37303 prot_pool --> prot_P37303 0.0 -usage_prot_P38009 usage_prot_P38009 prot_pool --> prot_P38009 0.07840419894299037 -usage_prot_P38013 usage_prot_P38013 prot_pool --> prot_P38013 0.0018784397678640423 +usage_prot_P38009 usage_prot_P38009 prot_pool --> prot_P38009 0.07840419894299733 +usage_prot_P38013 usage_prot_P38013 prot_pool --> prot_P38013 0.0 usage_prot_P38063 usage_prot_P38063 prot_pool --> prot_P38063 0.0 usage_prot_P38066 usage_prot_P38066 prot_pool --> prot_P38066 2.464763303253681e-06 -usage_prot_P38067 usage_prot_P38067 prot_pool --> prot_P38067 0.0 +usage_prot_P38067 usage_prot_P38067 prot_pool --> prot_P38067 0.0001511801050155935 usage_prot_P38071 usage_prot_P38071 prot_pool --> prot_P38071 0.0 usage_prot_P38074 usage_prot_P38074 prot_pool --> prot_P38074 0.0 -usage_prot_P38075 usage_prot_P38075 prot_pool --> prot_P38075 0.034415545541658855 -usage_prot_P38077 usage_prot_P38077 prot_pool --> prot_P38077 1.6232501068757477 +usage_prot_P38075 usage_prot_P38075 prot_pool --> prot_P38075 0.0 +usage_prot_P38077 usage_prot_P38077 prot_pool --> prot_P38077 0.0899304161778389 usage_prot_P38084 usage_prot_P38084 prot_pool --> prot_P38084 0.0 usage_prot_P38085 usage_prot_P38085 prot_pool --> prot_P38085 0.0 usage_prot_P38088 usage_prot_P38088 prot_pool --> prot_P38088 0.0 usage_prot_P38090 usage_prot_P38090 prot_pool --> prot_P38090 0.0 usage_prot_P38113 usage_prot_P38113 prot_pool --> prot_P38113 0.0 usage_prot_P38115 usage_prot_P38115 prot_pool --> prot_P38115 0.0 -usage_prot_P38122 usage_prot_P38122 prot_pool --> prot_P38122 0.00023230985563608517 +usage_prot_P38122 usage_prot_P38122 prot_pool --> prot_P38122 0.00023230985563643656 usage_prot_P38125 usage_prot_P38125 prot_pool --> prot_P38125 0.0 usage_prot_P38127 usage_prot_P38127 prot_pool --> prot_P38127 0.0009466875554804274 usage_prot_P38130 usage_prot_P38130 prot_pool --> prot_P38130 0.0 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0.0043555958324755836 +usage_prot_P38169 usage_prot_P38169 prot_pool --> prot_P38169 0.004354734929302544 usage_prot_P38174 usage_prot_P38174 prot_pool --> prot_P38174 0.0 usage_prot_P38196 usage_prot_P38196 prot_pool --> prot_P38196 0.0 usage_prot_P38211 usage_prot_P38211 prot_pool --> prot_P38211 0.0 usage_prot_P38218 usage_prot_P38218 prot_pool --> prot_P38218 0.0 -usage_prot_P38221 usage_prot_P38221 prot_pool --> prot_P38221 0.009874399303515042 -usage_prot_P38225 usage_prot_P38225 prot_pool --> prot_P38225 0.0 +usage_prot_P38221 usage_prot_P38221 prot_pool --> prot_P38221 0.009874399303534738 +usage_prot_P38225 usage_prot_P38225 prot_pool --> prot_P38225 4.125812359590317e-06 usage_prot_P38226 usage_prot_P38226 prot_pool --> prot_P38226 0.0 usage_prot_P38230 usage_prot_P38230 prot_pool --> prot_P38230 0.0 usage_prot_P38242 usage_prot_P38242 prot_pool --> prot_P38242 0.0 usage_prot_P38270 usage_prot_P38270 prot_pool --> prot_P38270 0.0 usage_prot_P38279 usage_prot_P38279 prot_pool --> prot_P38279 0.0 -usage_prot_P38286 usage_prot_P38286 prot_pool --> prot_P38286 0.01972280631101205 +usage_prot_P38286 usage_prot_P38286 prot_pool --> prot_P38286 0.02982198697010408 usage_prot_P38287 usage_prot_P38287 prot_pool --> prot_P38287 0.0 usage_prot_P38295 usage_prot_P38295 prot_pool --> prot_P38295 0.0 usage_prot_P38298 usage_prot_P38298 prot_pool --> prot_P38298 0.0 @@ -7417,25 +7417,25 @@ usage_prot_P38329 usage_prot_P38329 prot_pool --> prot_P38329 0.0 usage_prot_P38331 usage_prot_P38331 prot_pool --> prot_P38331 0.0 usage_prot_P38342 usage_prot_P38342 prot_pool --> prot_P38342 0.0 usage_prot_P38358 usage_prot_P38358 prot_pool --> prot_P38358 0.0 -usage_prot_P38359 usage_prot_P38359 prot_pool --> prot_P38359 0.03374014317423459 +usage_prot_P38359 usage_prot_P38359 prot_pool --> prot_P38359 0.03374014317423464 usage_prot_P38360 usage_prot_P38360 prot_pool --> prot_P38360 0.0 -usage_prot_P38361 usage_prot_P38361 prot_pool --> prot_P38361 0.27085157289081147 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usage_prot_P38774 usage_prot_P38774 prot_pool --> prot_P38774 0.0 -usage_prot_P38787 usage_prot_P38787 prot_pool --> prot_P38787 9.039989179718514e-06 +usage_prot_P38787 usage_prot_P38787 prot_pool --> prot_P38787 9.039989179732188e-06 usage_prot_P38790 usage_prot_P38790 prot_pool --> prot_P38790 0.0 usage_prot_P38791 usage_prot_P38791 prot_pool --> prot_P38791 0.0 -usage_prot_P38795 usage_prot_P38795 prot_pool --> prot_P38795 0.00212613212284239 +usage_prot_P38795 usage_prot_P38795 prot_pool --> prot_P38795 0.002126132122831299 usage_prot_P38812 usage_prot_P38812 prot_pool --> prot_P38812 0.0002134004977453421 usage_prot_P38816 usage_prot_P38816 prot_pool --> prot_P38816 0.0 usage_prot_P38818 usage_prot_P38818 prot_pool --> prot_P38818 0.0 -usage_prot_P38824 usage_prot_P38824 prot_pool --> prot_P38824 0.04426028465611058 -usage_prot_P38840 usage_prot_P38840 prot_pool --> prot_P38840 0.002796876960277035 +usage_prot_P38824 usage_prot_P38824 prot_pool --> prot_P38824 0.0 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0.0 usage_prot_P40545 usage_prot_P40545 prot_pool --> prot_P40545 0.0021440906329501146 -usage_prot_P40550 usage_prot_P40550 prot_pool --> prot_P40550 0.006903358459907748 +usage_prot_P40550 usage_prot_P40550 prot_pool --> prot_P40550 0.0 usage_prot_P40553 usage_prot_P40553 prot_pool --> prot_P40553 0.0 usage_prot_P40556 usage_prot_P40556 prot_pool --> prot_P40556 0.0 usage_prot_P40559 usage_prot_P40559 prot_pool --> prot_P40559 0.0 usage_prot_P40580 usage_prot_P40580 prot_pool --> prot_P40580 0.0 usage_prot_P40581 usage_prot_P40581 prot_pool --> prot_P40581 0.0 usage_prot_P40825 usage_prot_P40825 prot_pool --> prot_P40825 0.008859154130962155 -usage_prot_P40857 usage_prot_P40857 prot_pool --> prot_P40857 0.002333564315012345 +usage_prot_P40857 usage_prot_P40857 prot_pool --> prot_P40857 0.003528479847076438 usage_prot_P40884 usage_prot_P40884 prot_pool --> prot_P40884 0.0 usage_prot_P40885 usage_prot_P40885 prot_pool --> prot_P40885 0.0 usage_prot_P40886 usage_prot_P40886 prot_pool --> prot_P40886 0.0 @@ -7565,18 +7565,18 @@ usage_prot_P40975 usage_prot_P40975 prot_pool --> prot_P40975 0.0 usage_prot_P40988 usage_prot_P40988 prot_pool --> prot_P40988 2.4101980169772022e-05 usage_prot_P40989 usage_prot_P40989 prot_pool --> prot_P40989 0.0 usage_prot_P41277 usage_prot_P41277 prot_pool --> prot_P41277 0.0 -usage_prot_P41338 usage_prot_P41338 prot_pool --> prot_P41338 0.07401176011595327 +usage_prot_P41338 usage_prot_P41338 prot_pool --> prot_P41338 0.07327897041183487 usage_prot_P41734 usage_prot_P41734 prot_pool --> prot_P41734 0.0 usage_prot_P41735 usage_prot_P41735 prot_pool --> prot_P41735 0.0 usage_prot_P41807 usage_prot_P41807 prot_pool --> prot_P41807 0.0 usage_prot_P41815 usage_prot_P41815 prot_pool --> prot_P41815 0.0 usage_prot_P41835 usage_prot_P41835 prot_pool --> prot_P41835 1.214189334385453e-06 -usage_prot_P41903 usage_prot_P41903 prot_pool --> prot_P41903 0.0006175625125912523 -usage_prot_P41909 usage_prot_P41909 prot_pool --> prot_P41909 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usage_prot_P42837 usage_prot_P42837 prot_pool --> prot_P42837 0.0 usage_prot_P42884 usage_prot_P42884 prot_pool --> prot_P42884 0.0 -usage_prot_P42941 usage_prot_P42941 prot_pool --> prot_P42941 0.0033326180949401194 +usage_prot_P42941 usage_prot_P42941 prot_pool --> prot_P42941 0.0033328507691182613 usage_prot_P42951 usage_prot_P42951 prot_pool --> prot_P42951 0.0 usage_prot_P43123 usage_prot_P43123 prot_pool --> prot_P43123 0.00029226119444444447 usage_prot_P43534 usage_prot_P43534 prot_pool --> prot_P43534 2.469494595359409e-07 @@ -7598,60 +7598,60 @@ usage_prot_P43577 usage_prot_P43577 prot_pool --> prot_P43577 0.0011535923860329 usage_prot_P43581 usage_prot_P43581 prot_pool --> prot_P43581 0.0 usage_prot_P43601 usage_prot_P43601 prot_pool --> prot_P43601 0.0 usage_prot_P43616 usage_prot_P43616 prot_pool --> prot_P43616 0.0 -usage_prot_P43619 usage_prot_P43619 prot_pool --> prot_P43619 0.0009096962368462959 +usage_prot_P43619 usage_prot_P43619 prot_pool --> prot_P43619 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prot_Q07648 0.0 @@ -7902,23 +7902,23 @@ usage_prot_Q07824 usage_prot_Q07824 prot_pool --> prot_Q07824 0.0 usage_prot_Q07830 usage_prot_Q07830 prot_pool --> prot_Q07830 0.0 usage_prot_Q07923 usage_prot_Q07923 prot_pool --> prot_Q07923 0.0 usage_prot_Q07938 usage_prot_Q07938 prot_pool --> prot_Q07938 0.04973791082059297 -usage_prot_Q07950 usage_prot_Q07950 prot_pool --> prot_Q07950 6.586426736740415e-05 +usage_prot_Q07950 usage_prot_Q07950 prot_pool --> prot_Q07950 0.0 usage_prot_Q07993 usage_prot_Q07993 prot_pool --> prot_Q07993 0.0 usage_prot_Q08108 usage_prot_Q08108 prot_pool --> prot_Q08108 0.0 -usage_prot_Q08220 usage_prot_Q08220 prot_pool --> prot_Q08220 2.818939393922653e-08 +usage_prot_Q08220 usage_prot_Q08220 prot_pool --> prot_Q08220 2.818939393939394e-08 usage_prot_Q08224 usage_prot_Q08224 prot_pool --> prot_Q08224 9.499070103432113e-06 usage_prot_Q08227 usage_prot_Q08227 prot_pool --> prot_Q08227 0.0 usage_prot_Q08269 usage_prot_Q08269 prot_pool --> prot_Q08269 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prot_Q12455 0.0003639187688406843 usage_prot_Q12458 usage_prot_Q12458 prot_pool --> prot_Q12458 0.0 usage_prot_Q12471 usage_prot_Q12471 prot_pool --> prot_Q12471 0.0 usage_prot_Q12473 usage_prot_Q12473 prot_pool --> prot_Q12473 0.0 -usage_prot_Q12482 usage_prot_Q12482 prot_pool --> prot_Q12482 0.6269078360161031 +usage_prot_Q12482 usage_prot_Q12482 prot_pool --> prot_Q12482 0.5952962153022638 usage_prot_Q12494 usage_prot_Q12494 prot_pool --> prot_Q12494 0.0 usage_prot_Q12520 usage_prot_Q12520 prot_pool --> prot_Q12520 0.0 usage_prot_Q12524 usage_prot_Q12524 prot_pool --> prot_Q12524 0.0 usage_prot_Q12525 usage_prot_Q12525 prot_pool --> prot_Q12525 0.0 usage_prot_Q12674 usage_prot_Q12674 prot_pool --> prot_Q12674 0.0 usage_prot_Q12675 usage_prot_Q12675 prot_pool --> prot_Q12675 0.0 -usage_prot_Q12676 usage_prot_Q12676 prot_pool --> prot_Q12676 9.199454193904186e-06 +usage_prot_Q12676 usage_prot_Q12676 prot_pool --> prot_Q12676 9.1994541940678e-06 usage_prot_Q12680 usage_prot_Q12680 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prot_pool_exchange --> prot_pool 101.48362882763044 -usage_prot_standard usage_prot_standard prot_pool --> prot_standard 0.29863344595170077 +prot_pool_exchange prot_pool_exchange --> prot_pool 69.29093460408671 +usage_prot_standard usage_prot_standard prot_pool --> prot_standard 0.13137222513283695 diff --git a/results/modelSimulation/allFluxes_hGR.tsv b/results/modelSimulation/allFluxes_hGR.tsv index 54f0f52..dcf5510 100644 --- a/results/modelSimulation/allFluxes_hGR.tsv +++ b/results/modelSimulation/allFluxes_hGR.tsv @@ -16,9 +16,9 @@ r_0006_EXP_1 1,6-beta-glucan synthase 0.38423648758316814 prot_P33336 + UDP-D-gl r_0006_EXP_2 1,6-beta-glucan synthase 1.4417126800627231 prot_P32486 + UDP-D-glucose --> (1->6)-beta-D-glucan + H+ + UDP 0.0 r_0007 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase 0.25657118055555556 prot_P40545 + 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide --> 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide 0.0242344554134714 r_0012 1-pyrroline-5-carboxylate dehydrogenase 11.932407407407407 prot_P07275 + 1-pyrroline-5-carboxylate + 2.0 H2O + NAD --> H+ + L-glutamate + NADH 0.0 -r_0013 2,3-diketo-5-methylthio-1-phosphopentane degradation reaction 0.013992777777777778 prot_P32626 + 0.011599444444444445 prot_Q03677 + 5-(methylsulfanyl)-2,3-dioxopentyl phosphate + H2O + oxygen --> 4-methylthio-2-oxobutanoate + formate + 2.0 H+ + phosphate 0.0018332246222373496 -r_0014 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase 188.09203142536475 prot_Q12362 + 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + H+ + H2O --> 5-amino-6-(5-phosphoribitylamino)uracil + ammonium 0.00028999999161897003 -r_0015 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH) 0.5311659867712155 prot_P33312 + 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + H+ + NADPH --> 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + NADP(+) 0.00028999999161897003 +r_0013 2,3-diketo-5-methylthio-1-phosphopentane degradation reaction 0.013992777777777778 prot_P32626 + 0.011599444444444445 prot_Q03677 + 5-(methylsulfanyl)-2,3-dioxopentyl phosphate + H2O + oxygen --> 4-methylthio-2-oxobutanoate + formate + 2.0 H+ + phosphate 0.001833224622164148 +r_0014 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase 188.09203142536475 prot_Q12362 + 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + H+ + H2O --> 5-amino-6-(5-phosphoribitylamino)uracil + ammonium 0.00028999999162475826 +r_0015 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH) 0.5311659867712155 prot_P33312 + 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + H+ + NADPH --> 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone + NADP(+) 0.00028999999162475826 r_0016_EXP_1 2-aceto-2-hydroxybutanoate synthase 0.08099546044098574 prot_P07342 + 0.03673476005188067 prot_P25605 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.0 r_0016_EXP_2 2-aceto-2-hydroxybutanoate synthase 0.04049773022049287 prot_P07342 + 2-oxobutanoate + H+ + pyruvate --> (S)-2-acetyl-2-hydroxybutanoate + carbon dioxide 0.07699219285051538 r_0017 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 63.477512816721614 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + ATP --> (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + AMP + H+ 0.0 @@ -28,9 +28,9 @@ r_0018_EXP_3 2-aminoadipate transaminase 0.009033549783549784 prot_P47039 + 2-ox r_0018_REV_EXP_1 2-aminoadipate transaminase (reversible) 0.7210471896303212 prot_P10356 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 r_0018_REV_EXP_2 2-aminoadipate transaminase (reversible) 0.8480978260869565 prot_P53090 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 r_0018_REV_EXP_3 2-aminoadipate transaminase (reversible) 1.8137766188613647 prot_P47039 + 2-oxoglutarate + L-2-aminoadipate --> 2-oxoadipic acid + L-glutamate 0.0 -r_0019 2-dehydropantoate 2-reductase 0.4757888888888889 prot_P38787 + 2-dehydropantoate + H+ + NADPH --> (R)-pantoate + NADP(+) 5.510000177322283e-05 +r_0019 2-dehydropantoate 2-reductase 0.4757888888888889 prot_P38787 + 2-dehydropantoate + H+ + NADPH --> (R)-pantoate + NADP(+) 5.5100001772612206e-05 r_0020_EXP_1 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09351092896174863 prot_P14843 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 -r_0020_EXP_2 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.09701220164382707 +r_0020_EXP_2 2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.09701220164382451 r_0021 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase 0.2834173315594083 prot_O13525 + 0.266570923780901 prot_P27680 + 0.191209663200305 prot_P41735 + 0.2544937516539746 prot_P49017 + 0.39274288726487816 prot_P53318 + 0.21981040253855474 prot_Q05779 + 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine --> 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + S-adenosyl-L-homocysteine 0.0 r_0022 2-hexaprenyl-6-methoxyphenol monooxygenase 0.5305538973582232 prot_O13525 + 0.49901762096258073 prot_P27680 + 0.3579422312153493 prot_P41735 + 0.47640929737929355 prot_P49017 + 0.7352100464414428 prot_P53318 + 0.4114824774654426 prot_Q05779 + 2-hexaprenyl-6-methoxyphenol + oxygen --> 2-hexaprenyl-6-methoxy-1,4-benzoquinone + H2O 0.0 r_0023 2-isopropylmalate hydratase 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> 2-isopropylmalate 0.0 @@ -39,71 +39,71 @@ r_0024_EXP_1 2-isopropylmalate synthase 1.3779912980420594 prot_P06208 + 3-methy r_0024_EXP_2 2-isopropylmalate synthase 1.353637901861252 prot_Q12166 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.026427745067573668 r_0025 2-isopropylmalate synthase 1.3779912980420594 prot_P06208 + 3-methyl-2-oxobutanoate + acetyl-CoA + H2O --> 2-isopropylmalate + coenzyme A + H+ 0.0 r_0026_EXP_1 2-keto-4-methylthiobutyrate transamination 0.011265116279069768 prot_P38891 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 -r_0026_EXP_2 2-keto-4-methylthiobutyrate transamination 0.010755813953488373 prot_P47176 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0018332246222373496 +r_0026_EXP_2 2-keto-4-methylthiobutyrate transamination 0.010755813953488373 prot_P47176 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.001833224622164148 r_0026_EXP_3 2-keto-4-methylthiobutyrate transamination 1.219140625 prot_P53090 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 r_0026_EXP_4 2-keto-4-methylthiobutyrate transamination 1.5784250269687163 prot_P38840 + 4-methylthio-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-methionine 0.0 r_0027 2-methylcitrate dehydratase 8.195345706873871 prot_P49367 + homocitrate --> but-1-ene-1,2,4-tricarboxylic acid + H2O 0.09552589561639659 r_0027_REV 2-methylcitrate dehydratase (reversible) 8.350111111111111 prot_P49367 + but-1-ene-1,2,4-tricarboxylic acid + H2O --> homocitrate 0.0 -r_0028 2-methylcitrate synthase 0.10578556263269638 prot_P43635 + H2O + oxaloacetate + propionyl-CoA --> 2-methylcitrate + coenzyme A + H+ 0.0 +r_0028 2-methylcitrate synthase 0.10578556263269638 prot_P43635 + H2O + oxaloacetate + propionyl-CoA --> 2-methylcitrate + coenzyme A + H+ 0.00046145441014266997 r_0029 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.10513175524407464 r_0030 2-oxo-4-methyl-3-carboxypentanoate decarboxylation 0.048490056204063985 prot_standard + (2S)-2-isopropyl-3-oxosuccinate + H+ --> 4-methyl-2-oxopentanoate + carbon dioxide 0.0 -r_0032 3',5'-bisphosphate nucleotidase 0.9886111111111111 prot_P32179 + adenosine 3',5'-bismonophosphate + H2O --> AMP + phosphate 0.034582258179365 +r_0032 3',5'-bisphosphate nucleotidase 0.9886111111111111 prot_P32179 + adenosine 3',5'-bismonophosphate + H2O --> AMP + phosphate 0.03502494150086366 r_0033_EXP_1 3',5'-cyclic-nucleotide phosphodiesterase 0.5557671957671958 prot_P22434 + 3',5'-cyclic AMP + H2O --> AMP + H+ 0.0 r_0033_EXP_2 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic AMP + H2O --> AMP + H+ 0.0 r_0034 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic dAMP + H2O --> dAMP + H+ 0.0 r_0035 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic IMP + H2O --> H+ + IMP 0.0 r_0036 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic GMP + H2O --> GMP + H+ 0.0 r_0037 3',5'-cyclic-nucleotide phosphodiesterase 2.529021558872305 prot_P06776 + 3',5'-cyclic CMP + H2O --> CMP + H+ 0.0 -r_0038 3,4-dihydroxy-2-butanone-4-phosphate synthase 2.8494949494949493 prot_Q99258 + D-ribulose 5-phosphate --> 2-hydroxy-3-oxobutyl phosphate + formate + H+ 0.0005799999832379401 -r_0039 3-dehydroquinate dehydratase 0.1565905017921147 prot_P08566 + 3-dehydroquinate --> 3-dehydroshikimate + H2O 0.09701220164382707 -r_0040 3-dehydroquinate synthase 0.1565905017921147 prot_P08566 + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 3-dehydroquinate + phosphate 0.09701220164382707 +r_0038 3,4-dihydroxy-2-butanone-4-phosphate synthase 2.8494949494949493 prot_Q99258 + D-ribulose 5-phosphate --> 2-hydroxy-3-oxobutyl phosphate + formate + H+ 0.0005799999832495165 +r_0039 3-dehydroquinate dehydratase 0.1565905017921147 prot_P08566 + 3-dehydroquinate --> 3-dehydroshikimate + H2O 0.09701220164382451 +r_0040 3-dehydroquinate synthase 0.1565905017921147 prot_P08566 + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 3-dehydroquinate + phosphate 0.09701220164382451 r_0041 3-dehydrosphinganine reductase 9.338785046728972 prot_P38342 + 3-ketosphinganine + H+ + NADPH --> NADP(+) + sphinganine 0.0 r_0042_EXP_1 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09050318761384335 prot_P32449 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 r_0042_EXP_2 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase 0.09351092896174863 prot_P14843 + D-erythrose 4-phosphate + H2O + phosphoenolpyruvate --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid + phosphate 0.0 r_0043_EXP_1 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase 0.2467406921478821 prot_Q12184 + 3-hexaprenyl-4-hydroxybenzoic acid + 0.5 oxygen --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 r_0043_EXP_2 3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase 0.30872310057092667 prot_P48360 + 3-hexaprenyl-4-hydroxybenzoic acid + 0.5 oxygen --> 3-hexaprenyl-4,5-dihydroxybenzoic acid 0.0 r_0044 3-hexaprenyl-4-hydroxy-5-methoxybenzoate decarboxylase 1.6143115942028985 prot_P33751 + 3.391545893719807 prot_Q03034 + 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid + H+ --> 2-hexaprenyl-6-methoxyphenol + carbon dioxide 0.0 -r_0045 3-hydroxy-L-kynurenine hydrolase 4.0501587301587305 prot_Q05979 + 3-hydroxy-L-kynurenine + H2O --> 3-hydroxyanthranilate + H+ + L-alanine 0.0017602999924600823 +r_0045 3-hydroxy-L-kynurenine hydrolase 4.0501587301587305 prot_Q05979 + 3-hydroxy-L-kynurenine + H2O --> 3-hydroxyanthranilate + H+ + L-alanine 0.0017602999924575258 r_0057 3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA) 0.07066365979381443 prot_Q02207 + (S)-3-hydroxytetradecanoyl-CoA + NAD --> 3-oxotetradecanoyl-CoA + H+ + NADH 0.0 -r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.22483333333333333 prot_P47096 + 3-hydroxyanthranilate + oxygen --> 2-amino-3-carboxymuconate-6-semialdehyde 0.0017602999924600823 +r_0058 3-hydroxyanthranilate 3,4-dioxygenase 0.22483333333333333 prot_P47096 + 3-hydroxyanthranilate + oxygen --> 2-amino-3-carboxymuconate-6-semialdehyde 0.0017602999924575258 r_0059 3-isopropylmalate 3-methyltransferase 195.1806339044363 prot_P32643 + (2R,3S)-3-isopropylmalate + S-adenosyl-L-methionine --> 3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoate + S-adenosyl-L-homocysteine 0.0 r_0060 3-isopropylmalate dehydratase 0.6097968324816225 prot_P07264 + (2R,3S)-3-isopropylmalate --> 2-isopropylmaleic acid + H2O 0.0 r_0060_REV 3-isopropylmalate dehydratase (reversible) 0.7297564816305446 prot_P07264 + 2-isopropylmaleic acid + H2O --> (2R,3S)-3-isopropylmalate 0.10513175524407464 r_0061 3-isopropylmalate dehydrogenase 0.06638207225630538 prot_P04173 + (2R,3S)-3-isopropylmalate + NAD --> (2S)-2-isopropyl-3-oxosuccinate + H+ + NADH 0.10513175524407464 r_0062_EXP_1 3-methyl-2-oxobutanoate decarboxylase 0.27589605734767025 prot_P26263 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 -r_0062_EXP_2 3-methyl-2-oxobutanoate decarboxylase 0.11780651340996169 prot_P06169 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde -1.2006506899808755e-12 +r_0062_EXP_2 3-methyl-2-oxobutanoate decarboxylase 0.11780651340996169 prot_P06169 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 r_0062_EXP_3 3-methyl-2-oxobutanoate decarboxylase 0.27738351254480287 prot_P16467 + 3-methyl-2-oxobutanoate + H+ --> carbon dioxide + isobutyraldehyde 0.0 -r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.226834113807293 prot_P38122 + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O --> 2-dehydropantoate + THF 5.510000177322283e-05 +r_0063 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.226834113807293 prot_P38122 + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O --> 2-dehydropantoate + THF 5.5100001772612206e-05 r_0064_EXP_1 3-methyl-2-oxopentanoate decarboxylase 0.13096934865900384 prot_Q07471 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_2 3-methyl-2-oxopentanoate decarboxylase 0.27589605734767025 prot_P26263 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_3 3-methyl-2-oxopentanoate decarboxylase 0.11780651340996169 prot_P06169 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 r_0064_EXP_4 3-methyl-2-oxopentanoate decarboxylase 0.27738351254480287 prot_P16467 + (S)-3-methyl-2-oxopentanoate + H+ --> 2-methylbutanal + carbon dioxide 0.0 -r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 1.4447337962962963 prot_P08566 + 3-phosphoshikimic acid + phosphoenolpyruvate --> 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid + phosphate 0.09701220164382707 +r_0065 3-phosphoshikimate 1-carboxyvinyltransferase 1.4447337962962963 prot_P08566 + 3-phosphoshikimic acid + phosphoenolpyruvate --> 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid + phosphate 0.09701220164382451 r_0066 4-amino-4-deoxychorismate synthase 1446.797385620915 prot_P37254 + chorismate + L-glutamine --> 4-amino-4-deoxychorismate + L-glutamate 1.83860007382311e-05 r_0067 4-aminobenzoate synthase 6.233918128654971 prot_Q03266 + 4-amino-4-deoxychorismate --> 4-aminobenzoate + H+ + pyruvate 1.83860007382311e-05 -r_0068 4-aminobutyrate transaminase 43.25653594771242 prot_P17649 + 2-oxoglutarate + gamma-aminobutyrate --> L-glutamate + succinic semialdehyde 0.0 +r_0068 4-aminobutyrate transaminase 43.25653594771242 prot_P17649 + 2-oxoglutarate + gamma-aminobutyrate --> L-glutamate + succinic semialdehyde 0.0005396697347794296 r_0069 4-hydroxy-L-threonine synthase 0.003912990196078431 prot_P16120 + 4-(phosphonooxy)-L-threonine + H2O --> 4-hydroxy-L-threonine + phosphate 0.0 r_0070 4-hydroxybenzoate formation 0.6162073031087573 prot_standard + 4-hydroxybenzoyl-CoA + H2O --> 4-hydroxybenzoate + coenzyme A + H+ 0.0 r_0072 4-methyl-2-oxopentanoate decarboxylase 2.2341830065359476 prot_Q07471 + 4-methyl-2-oxopentanoate + H+ --> 3-methylbutanal + carbon dioxide 0.0 r_0073_EXP_1 4PP-IP5 depyrophosphorylation to IP6 0.9485014619883041 prot_Q06685 + 4-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0073_EXP_2 4PP-IP5 depyrophosphorylation to IP6 2396.8888888888887 prot_Q99321 + 4-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0074 4PP-IP5 pyrophosphorylation to 4,5-PP2-IP4 1106.9444444444443 prot_Q12494 + 4-diphospho-1D-myo-inositol pentakisphosphate + ATP + H+ --> 4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate + ADP 0.0 -r_0075 5'-methylthioadenosine phosphorylase 40.44551282051282 prot_Q07938 + 5'-S-methyl-5'-thioadenosine + phosphate --> adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate 0.0018332246222373496 +r_0075 5'-methylthioadenosine phosphorylase 40.44551282051282 prot_Q07938 + 5'-S-methyl-5'-thioadenosine + phosphate --> adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate 0.001833224622164148 r_0076_EXP_1 5'-nucleotidase (CMP) 0.029597457627118642 prot_P40025 + CMP + H2O --> cytidine + phosphate 0.0 r_0076_EXP_2 5'-nucleotidase (CMP) 51.769157967243395 prot_P53078 + CMP + H2O --> cytidine + phosphate 0.0 r_0077 5'-nucleotidase (IMP) 1.056172839506173 prot_Q99312 + H2O + IMP --> inosine + phosphate 0.0 r_0078_EXP_1 5'-nucleotidase (UMP) 0.029597457627118642 prot_P40025 + H2O + UMP --> phosphate + uridine 0.0 r_0078_EXP_2 5'-nucleotidase (UMP) 201.12835425109543 prot_P53078 + H2O + UMP --> phosphate + uridine 0.0 -r_0079 5'-phosphoribosylformyl glycinamidine synthetase 112.56379587281619 prot_P38972 + 5'-phosphoribosyl-N-formylglycineamide + ATP + H2O + L-glutamine --> 5'-phosphoribosyl-N-formylglycineamidine + ADP + H+ + L-glutamate + phosphate 0.02969723651725126 -r_0080_EXP_1 5,10-methylenetetrahydrofolate reductase (NADPH) 0.12837152777777777 prot_P46151 + 0.11902777777777777 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.06454311029984798 +r_0079 5'-phosphoribosylformyl glycinamidine synthetase 112.56379587281619 prot_P38972 + 5'-phosphoribosyl-N-formylglycineamide + ATP + H2O + L-glutamine --> 5'-phosphoribosyl-N-formylglycineamidine + ADP + H+ + L-glutamate + phosphate 0.029697236517247882 +r_0080_EXP_1 5,10-methylenetetrahydrofolate reductase (NADPH) 0.12837152777777777 prot_P46151 + 0.11902777777777777 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.06454311029984797 r_0080_EXP_2 5,10-methylenetetrahydrofolate reductase (NADPH) 0.3705144833549503 prot_P53128 + 5,10-methylenetetrahydrofolate + H+ + NADPH --> 5-methyltetrahydrofolate + NADP(+) 0.0 r_0081 5-aminolevulinate synthase 0.08588252314814815 prot_P09950 + H+ + L-glycine + succinyl-CoA --> 5-aminolevulinate + carbon dioxide + coenzyme A 2.3199999941425633e-06 r_0082 5-diphosphoinositol-1,2,3,4,6-pentakisphosphate diphosphohydrolase 2396.8888888888887 prot_Q99321 + 5-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0083 5-diphosphoinositol-1,2,3,4,6-pentakisphosphate synthase 1106.9444444444443 prot_Q12494 + ATP + myo-inositol hexakisphosphate --> 5-diphospho-1D-myo-inositol pentakisphosphate + ADP 0.0 r_0084 5-formethyltetrahydrofolate cyclo-ligase 6.683055555555556 prot_P40099 + 5-formyltetrahydrofolic acid + ATP --> 5,10-methenyl-THF + ADP + phosphate 0.0 r_0085 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase 72.27272727272727 prot_P05694 + 5-methyltetrahydropteroyltri-L-glutamic acid + L-homocysteine --> L-methionine + tetrahydropteroyltri-L-glutamic acid 0.0 -r_0086 5-methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase 0.4617340067340067 prot_P47095 + S-methyl-5-thio-D-ribulose 1-phosphate --> 5-(methylsulfanyl)-2,3-dioxopentyl phosphate + H2O 0.0018332246222373496 -r_0087 5-methylthioribose-1-phosphate isomerase 0.961965811965812 prot_Q06489 + S-methyl-5-thio-alpha-D-ribose 1-phosphate --> S-methyl-5-thio-D-ribulose 1-phosphate 0.0018332246222373496 +r_0086 5-methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase 0.4617340067340067 prot_P47095 + S-methyl-5-thio-D-ribulose 1-phosphate --> 5-(methylsulfanyl)-2,3-dioxopentyl phosphate + H2O 0.001833224622164148 +r_0087 5-methylthioribose-1-phosphate isomerase 0.961965811965812 prot_Q06489 + S-methyl-5-thio-alpha-D-ribose 1-phosphate --> S-methyl-5-thio-D-ribulose 1-phosphate 0.001833224622164148 r_0087_REV 5-methylthioribose-1-phosphate isomerase (reversible) 0.961965811965812 prot_Q06489 + S-methyl-5-thio-D-ribulose 1-phosphate --> S-methyl-5-thio-alpha-D-ribose 1-phosphate 0.0 r_0088 5PP-IP5 pyrophosphorylation to 4,5-PP2-IP4 0.9485014619883041 prot_Q06685 + 5-diphospho-1D-myo-inositol pentakisphosphate + 2.0 H+ + phosphate --> 4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate + H2O 0.0 r_0088_REV 5PP-IP5 pyrophosphorylation to 4,5-PP2-IP4 (reversible) 0.9485014619883041 prot_Q06685 + 4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate + H2O --> 5-diphospho-1D-myo-inositol pentakisphosphate + 2.0 H+ + phosphate 0.0 @@ -111,7 +111,7 @@ r_0089 5PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 0.9485014619883041 prot_Q06685 r_0089_REV 5PP-IP5 pyrophosphorylation to 5,6-PP2-IP4 (reversible) 0.9485014619883041 prot_Q06685 + 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + H2O --> 5-diphospho-1D-myo-inositol pentakisphosphate + 2.0 H+ + phosphate 0.0 r_0090_EXP_1 6-phosphofructo-2-kinase 0.4896069182389937 prot_P40433 + ATP + D-fructose 6-phosphate --> ADP + beta-D-fructose 2,6-bisphosphate + H+ 0.0 r_0090_EXP_2 6-phosphofructo-2-kinase 0.23751572327044027 prot_Q12471 + ATP + D-fructose 6-phosphate --> ADP + beta-D-fructose 2,6-bisphosphate + H+ 0.0 -r_0091_EXP_1 6-phosphogluconolactonase 0.8951362104267674 prot_P53315 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.12580530351904917 +r_0091_EXP_1 6-phosphogluconolactonase 0.8951362104267674 prot_P53315 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.02937891401924715 r_0091_EXP_2 6-phosphogluconolactonase 0.87424298616765 prot_P38858 + 6-O-phosphono-D-glucono-1,5-lactone + H2O --> 6-phospho-D-gluconate + H+ 0.04541770998250334 r_0092_EXP_1 6PP-IP5 depyrophosphorylation to IP6 0.9485014619883041 prot_Q06685 + 6-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 r_0092_EXP_2 6PP-IP5 depyrophosphorylation to IP6 2396.8888888888887 prot_Q99321 + 6-diphospho-1D-myo-inositol pentakisphosphate + H2O --> H+ + myo-inositol hexakisphosphate + phosphate 0.0 @@ -120,9 +120,9 @@ r_0094 8-amino-7-oxononanoate synthase 1.1329040404040405 prot_standard + H+ + L r_0095_EXP_1 acetaldehyde condensation 0.27589605734767025 prot_P26263 + 2.0 acetaldehyde --> (R)-acetoin 0.0 r_0095_EXP_2 acetaldehyde condensation 0.11780651340996169 prot_P06169 + 2.0 acetaldehyde --> (R)-acetoin 0.0 r_0095_EXP_3 acetaldehyde condensation 0.27738351254480287 prot_P16467 + 2.0 acetaldehyde --> (R)-acetoin 0.0 -r_0096 acetohydroxy acid isomeroreductase 0.6734669095324833 prot_P06168 + 2-acetyllactic acid + H+ + NADPH --> (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) 0.19642217467935663 +r_0096 acetohydroxy acid isomeroreductase 0.6734669095324833 prot_P06168 + 2-acetyllactic acid + H+ + NADPH --> (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) 0.19642217468055667 r_0097_EXP_1 acetolactate synthase 0.16199092088197148 prot_P07342 + 0.07346952010376134 prot_P25605 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.0 -r_0097_EXP_2 acetolactate synthase 0.08099546044098574 prot_P07342 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.19642217467935663 +r_0097_EXP_2 acetolactate synthase 0.08099546044098574 prot_P07342 + H+ + 2.0 pyruvate --> 2-acetyllactic acid + carbon dioxide 0.19642217468055667 r_0099 acetyl-CoA ACP transacylase 0.2585296857817232 prot_P32463 + acetyl-CoA + ACP1 --> acetyl-ACP + coenzyme A 0.0 r_0099_REV acetyl-CoA ACP transacylase (reversible) 0.29722261474049355 prot_P32463 + acetyl-ACP + coenzyme A --> acetyl-CoA + ACP1 0.0 r_0100 acetyl-CoA C-acyltransferase (palmitoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxooctadecanoyl-CoA + coenzyme A --> acetyl-CoA + palmitoyl-CoA 0.0 @@ -130,27 +130,27 @@ r_0101 acetyl-CoA C-acyltransferase (tetracosanoyl-CoA) 0.839527027027027 prot_P r_0102 acetyl-CoA C-acyltransferase (myristoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxopalmitoyl-CoA + coenzyme A --> acetyl-CoA + myristoyl-CoA 0.0 r_0103 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.0 r_0103_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA 0.0 -r_0104 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.06416760246059944 +r_0104 acetyl-CoA C-acetyltransferase 3.311825396825397 prot_P41338 + 2.0 acetyl-CoA --> acetoacetyl-CoA + coenzyme A 0.06416760246059945 r_0104_REV acetyl-CoA C-acetyltransferase (reversible) 3.863796296296296 prot_P41338 + acetoacetyl-CoA + coenzyme A --> 2.0 acetyl-CoA 0.0 r_0105 acetyl-CoA C-acyltransferase (lauroyl-CoA) 0.839527027027027 prot_P27796 + 3-oxotetradecanoyl-CoA + coenzyme A --> acetyl-CoA + lauroyl-CoA 0.0 r_0106 acetyl-CoA C-acyltransferase (octanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxodecanoyl-CoA + coenzyme A --> acetyl-CoA + octanoyl-CoA 0.0 r_0107 acetyl-CoA C-acyltransferase (decanoyl-CoA) 0.839527027027027 prot_P27796 + 3-oxolauroyl-CoA + coenzyme A --> acetyl-CoA + decanoyl-CoA 0.0 r_0108 acetyl-Coa carboxylase 8.46937908496732 prot_P32874 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.0 -r_0109 acetyl-CoA carboxylase, reaction 2.608229839040149 prot_P48445 + 8.55097579839999 prot_Q00955 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.3433507730278202 +r_0109 acetyl-CoA carboxylase, reaction 2.608229839040149 prot_P48445 + 8.55097579839999 prot_Q00955 + acetyl-CoA + ATP + bicarbonate --> ADP + H+ + malonyl-CoA + phosphate 0.34335077302782024 r_0111 acetyl-CoA hydrolase 2.24640342822161 prot_P32316 + acetyl-CoA + H2O --> acetate + coenzyme A + H+ 0.0 r_0112_EXP_1 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 -r_0112_EXP_2 acetyl-CoA synthetase 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.5355763085779187 -r_0113 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.18432962398926245 +r_0112_EXP_2 acetyl-CoA synthetase 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.9349968449180359 +r_0113 acetyl-CoA synthetase 0.35230146011396013 prot_Q01574 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.18432962398927852 r_0114 acetyl-CoA synthetase nuclear 0.33605769230769234 prot_P52910 + acetate + ATP + coenzyme A --> acetyl-CoA + AMP + diphosphate 0.0 r_0115 acetylglutamate kinase 3.4224025974025976 prot_Q01217 + ATP + N-acetyl-L-glutamate --> ADP + N-acetyl-L-gamma-glutamyl phosphate 0.09038718640525792 r_0116_EXP_1 acid phosphatase (secreted) 12.535888834043245 prot_P00635 + FMN + H2O --> phosphate + riboflavin 0.0 r_0116_EXP_2 acid phosphatase (secreted) 2.079636552290633 prot_P35842 + FMN + H2O --> phosphate + riboflavin 0.0 r_0116_EXP_3 acid phosphatase (secreted) 8.09317955304032 prot_P24031 + FMN + H2O --> phosphate + riboflavin 0.0 r_0116_EXP_4 acid phosphatase (secreted) 2.0162205390505443 prot_P38693 + FMN + H2O --> phosphate + riboflavin 0.0 -r_0117 aconitase 356.0740740740741 prot_Q12428 + 2-methylcitrate --> (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid 0.0 +r_0117 aconitase 356.0740740740741 prot_Q12428 + 2-methylcitrate --> (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid 0.00046145441014266997 r_0117_REV aconitase (reversible) 0.0015170737865303288 prot_Q12428 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> 2-methylcitrate 0.0 r_0118 acteylornithine transaminase 5.836456209941037 prot_P18544 + 2-acetamido-5-oxopentanoate + L-glutamate --> 2-oxoglutarate + N(2)-acetyl-L-ornithine 0.0903871864052579 -r_0119 acyl carrier protein synthase 1.9814484126984127 prot_Q12036 + coenzyme A + H2O --> adenosine 3',5'-bismonophosphate + 2.0 H+ + pantetheine 4'-phosphate 0.0 +r_0119 acyl carrier protein synthase 1.9814484126984127 prot_Q12036 + coenzyme A + H2O --> adenosine 3',5'-bismonophosphate + 2.0 H+ + pantetheine 4'-phosphate 0.0004426833214992709 r_0120 acyl-CoA oxidase (decanoyl-CoA) 15.258169934640524 prot_P13711 + decanoyl-CoA + oxygen --> hydrogen peroxide + trans-dec-2-enoyl-CoA 0.0 r_0121 acyl-CoA oxidase (dodecanoyl-CoA) 2.7176949941792783 prot_P13711 + lauroyl-CoA + oxygen --> hydrogen peroxide + trans-dodec-2-enoyl-CoA 0.0 r_0122 acyl-CoA oxidase (hexacosanoyl-CoA) 2.7176949941792783 prot_P13711 + hexacosanoyl-CoA + oxygen --> hydrogen peroxide + trans-hexacos-2-enoyl-CoA 0.0 @@ -184,30 +184,30 @@ r_0138 adenine deaminase 2.0017676767676766 prot_P53909 + adenine + H+ + H2O --> r_0139_EXP_1 adenine phosphoribosyltransferase 0.5950339406931047 prot_P36973 + adenine + PRPP --> AMP + diphosphate 0.0 r_0139_EXP_2 adenine phosphoribosyltransferase 0.6129272359175896 prot_P49435 + adenine + PRPP --> AMP + diphosphate 0.0 r_0140 adenosine deaminase 2.0017676767676766 prot_P53909 + adenosine + H+ + H2O --> ammonium + inosine 0.0 -r_0142 adenosine kinase 0.3962091503267974 prot_P47143 + adenosine + ATP --> ADP + AMP + H+ 0.042742069644990235 +r_0142 adenosine kinase 0.3962091503267974 prot_P47143 + adenosine + ATP --> ADP + AMP + H+ 0.04274206964491703 r_0143 adenosine monophosphate deaminase 21.282895302745313 prot_P15274 + AMP + H+ + H2O --> ammonium + IMP 0.0 -r_0144 adenosylhomocysteinase 0.023732367149758453 prot_P39954 + H2O + S-adenosyl-L-homocysteine --> adenosine + L-homocysteine 0.04090884502275289 -r_0145 adenosylmethionine decarboxylase 7.554248366013072 prot_P21182 + H+ + S-adenosyl-L-methionine --> carbon dioxide + S-adenosylmethioninamine 0.0018332246222373496 +r_0144 adenosylhomocysteinase 0.023732367149758453 prot_P39954 + H2O + S-adenosyl-L-homocysteine --> adenosine + L-homocysteine 0.04090884502275288 +r_0145 adenosylmethionine decarboxylase 7.554248366013072 prot_P21182 + H+ + S-adenosyl-L-methionine --> carbon dioxide + S-adenosylmethioninamine 0.001833224622164148 r_0146 adenosylmethionine-8-amino-7-oxononanoate transaminase 14.919166666666667 prot_P50277 + 8-amino-7-oxononanoate + S-adenosyl-L-methionine --> 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate 0.0 r_0146_REV adenosylmethionine-8-amino-7-oxononanoate transaminase (reversible) 14.919166666666667 prot_P50277 + 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate --> 8-amino-7-oxononanoate + S-adenosyl-L-methionine 0.0 r_0147 adenylate cyclase 0.013758091787439614 prot_P08678 + ATP --> 3',5'-cyclic AMP + diphosphate 0.0 r_0148_EXP_1 adenylate kinase 0.007176741835638936 prot_Q12055 + AMP + ATP --> 2.0 ADP 0.208438367908207 -r_0148_EXP_2 adenylate kinase 0.007660602615122228 prot_P07170 + AMP + ATP --> 2.0 ADP 1.968266530873731 -r_0149 adenylate kinase 10.450950897581233 prot_P26364 + AMP + ATP --> 2.0 ADP 0.184329623989262 +r_0148_EXP_2 adenylate kinase 0.007660602615122228 prot_P07170 + AMP + ATP --> 2.0 ADP 2.368129750535262 +r_0149 adenylate kinase 10.450950897581233 prot_P26364 + AMP + ATP --> 2.0 ADP 0.18432962398927852 r_0150 adenylate kinase (GTP) 10.495327582667667 prot_P26364 + AMP + GTP --> ADP + GDP 0.0 r_0150_REV adenylate kinase (GTP) (reversible) 2.5045140533551153 prot_P26364 + ADP + GDP --> AMP + GTP 0.0 -r_0151 adenylosuccinate lyase (AICAR) 0.04493076162215628 prot_Q05911 + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole --> AICAR + fumarate 0.029696888517238947 -r_0152 adenylosuccinate lyase 0.04493076162215628 prot_Q05911 + adenylo-succinate --> AMP + fumarate 0.04001185664749664 +r_0151 adenylosuccinate lyase (AICAR) 0.04493076162215628 prot_Q05911 + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole --> AICAR + fumarate 0.029696888517235575 +r_0152 adenylosuccinate lyase 0.04493076162215628 prot_Q05911 + adenylo-succinate --> AMP + fumarate 0.040011856647487465 r_0152_REV adenylosuccinate lyase (reversible) 5.221264367816092 prot_Q05911 + AMP + fumarate --> adenylo-succinate 0.0 -r_0153 adenylosuccinate synthase 2.4383333333333335 prot_P80210 + GTP + IMP + L-aspartate --> adenylo-succinate + GDP + 2.0 H+ + phosphate 0.04001185664749664 -r_0154 adenylyl-sulfate kinase 1.4558080808080807 prot_Q02196 + 5'-adenylyl sulfate + ATP --> 3'-phospho-5'-adenylyl sulfate + ADP + H+ 0.034582258179365 +r_0153 adenylosuccinate synthase 2.4383333333333335 prot_P80210 + GTP + IMP + L-aspartate --> adenylo-succinate + GDP + 2.0 H+ + phosphate 0.040011856647487465 +r_0154 adenylyl-sulfate kinase 1.4558080808080807 prot_Q02196 + 5'-adenylyl sulfate + ATP --> 3'-phospho-5'-adenylyl sulfate + ADP + H+ 0.03458225817936439 r_0155 ADP-ribose 2,3-cyclic phosphodiesterase 0.00789952718676123 prot_P53314 + 2',3'-cyclic AMP + H2O --> adenosine 2'-phosphate + H+ 0.0 r_0156 alanine glyoxylate aminotransferase 0.08886132315521629 prot_P43567 + glyoxylate + L-alanine --> L-glycine + pyruvate 0.0 r_0157 alanyl-tRNA synthetase 0.25476620370370373 prot_P40825 + ATP + L-alanine + tRNA(Ala) --> Ala-tRNA(Ala) + AMP + diphosphate 0.10084362292288122 r_0158_EXP_1 alcohol acetyltransferase (2-methylbutanol) 0.00442002285061411 prot_P53296 + 2-methylbutanol + acetyl-CoA --> 2-methylbutyl acetate + coenzyme A 0.0 r_0158_EXP_2 alcohol acetyltransferase (2-methylbutanol) 0.004358469008854613 prot_P40353 + 2-methylbutanol + acetyl-CoA --> 2-methylbutyl acetate + coenzyme A 0.0 r_0159_EXP_1 alcohol acetyltransferase (ethanol) 0.00442002285061411 prot_P53296 + acetyl-CoA + ethanol --> coenzyme A + ethyl acetate 0.0 -r_0159_EXP_2 alcohol acetyltransferase (ethanol) 0.004358469008854613 prot_P40353 + acetyl-CoA + ethanol --> coenzyme A + ethyl acetate 0.0 +r_0159_EXP_2 alcohol acetyltransferase (ethanol) 0.004358469008854613 prot_P40353 + acetyl-CoA + ethanol --> coenzyme A + ethyl acetate 0.39888062410379055 r_0160_EXP_1 alcohol acetyltransferase (isoamyl alcohol) 0.00442002285061411 prot_P53296 + acetyl-CoA + isoamylol --> coenzyme A + isoamyl acetate 0.0 r_0160_EXP_2 alcohol acetyltransferase (isoamyl alcohol) 0.004358469008854613 prot_P40353 + acetyl-CoA + isoamylol --> coenzyme A + isoamyl acetate 0.0 r_0161_EXP_1 alcohol acetyltransferase (isobutyl alcohol) 0.00442002285061411 prot_P53296 + acetyl-CoA + isobutanol --> coenzyme A + isobutyl acetate 0.0 @@ -235,11 +235,11 @@ r_0170_EXP_2 aldehyde dehydrogenase (2-phenylethanol, NAD) 0.006814054134343373 r_0171_EXP_1 aldehyde dehydrogenase (2-phenylethanol, NADP) 1.6815384615384616 prot_P25377 + H+ + NADPH + phenylacetaldehyde --> 2-phenylethanol + NADP(+) 0.0 r_0171_EXP_2 aldehyde dehydrogenase (2-phenylethanol, NADP) 0.012227777777777778 prot_Q04894 + H+ + NADPH + phenylacetaldehyde --> 2-phenylethanol + NADP(+) 0.0 r_0172_EXP_1 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.483596214511041 prot_P47771 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 0.0 -r_0172_EXP_2 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.06410300925925926 prot_P54114 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 0.0018332246222373496 -r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 1.229492014798566 -r_0174 aldehyde dehydrogenase (acetylaldehyde, NAD) 1.6231765567058962 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 1.925472201565201 -r_0175_EXP_1 aldehyde dehydrogenase (acetylaldehyde, NADP) 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.006938868180636604 -r_0175_EXP_2 aldehyde dehydrogenase (acetylaldehyde, NADP) 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.356862685754493 +r_0172_EXP_2 aldehyde dehydrogenase (3-aminopropanal, NAD) 0.06410300925925926 prot_P54114 + 3-aminopropanal + H2O + NAD --> beta-alanine + 2.0 H+ + NADH 0.001833224622164148 +r_0173 aldehyde dehydrogenase (acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 1.628912551138684 +r_0174 aldehyde dehydrogenase (acetylaldehyde, NAD) 1.6231765567058962 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.21841665526103315 +r_0175_EXP_1 aldehyde dehydrogenase (acetylaldehyde, NADP) 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.0 +r_0175_EXP_2 aldehyde dehydrogenase (acetylaldehyde, NADP) 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NADP(+) --> acetate + 2.0 H+ + NADPH 0.36380155393632996 r_0176 aldehyde dehydrogenase (indole-3-acetaldehyde, NAD) 2.9233283159832175 prot_P46367 + H2O + indol-3-ylacetaldehyde + NAD --> 2.0 H+ + indole-3-acetate + NADH 0.0 r_0177 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 0.6870454545454545 prot_P54115 + H2O + indol-3-ylacetaldehyde + NADP(+) --> 2.0 H+ + indole-3-acetate + NADPH 0.0 r_0178_EXP_1 aldehyde dehydrogenase (indole-3-acetaldehyde, NADP) 2.027300005914026 prot_P40047 + H2O + indol-3-ylacetaldehyde + NADP(+) --> 2.0 H+ + indole-3-acetate + NADPH 0.0 @@ -294,8 +294,8 @@ r_0199_EXP_1 amidase 0.002363959719142646 prot_P22580 + 4-guanidinobutanamide + r_0199_EXP_2 amidase 0.002263428815277111 prot_Q03557 + 4-guanidinobutanamide + H2O --> 4-guanidinobutanoic acid + ammonium 0.0 r_0200 Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing) 0.062476381011109826 prot_standard + aminoacetone + H2O + oxygen --> ammonium + hydrogen peroxide + methylglyoxal 0.0 r_0201 Aminobutyraldehyde dehydrogenase 6.571504396261395 prot_P46367 + 4-aminobutanal + H2O + NAD --> gamma-aminobutyrate + 2.0 H+ + NADH 0.0 -r_0202 anthranilate phosphoribosyltransferase 2.8570423609142406 prot_P07285 + anthranilate + PRPP --> diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate 0.013075001647262715 -r_0203 anthranilate synthase 0.11426731078904992 prot_P00899 + 0.1076670692431562 prot_P00937 + chorismate + L-glutamine --> anthranilate + H+ + L-glutamate + pyruvate 0.012945546185412962 +r_0202 anthranilate phosphoribosyltransferase 2.8570423609142406 prot_P07285 + anthranilate + PRPP --> diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate 0.013075001647263247 +r_0203 anthranilate synthase 0.11426731078904992 prot_P00899 + 0.1076670692431562 prot_P00937 + chorismate + L-glutamine --> anthranilate + H+ + L-glutamate + pyruvate 0.012945546185410405 r_0204 Ap4A hydrolase 0.16307795442894646 prot_P49775 + H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate --> 2.0 ADP + 2.0 H+ 0.0 r_0204_REV Ap4A hydrolase (reversible) 0.1607002693067822 prot_P49775 + 2.0 ADP + 2.0 H+ --> H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate 0.0 r_0205 arabinose reductase 0.01001051779935275 prot_P38715 + H+ + L-arabinose + NADPH --> L-arabinitol + NADP(+) 0.0 @@ -310,25 +310,25 @@ r_0211_EXP_1 asparagine synthase (glutamine-hydrolysing) 1.9523939064200218 prot r_0211_EXP_2 asparagine synthase (glutamine-hydrolysing) 1.948676097207109 prot_P49089 + ATP + H2O + L-aspartate + L-glutamine --> AMP + diphosphate + H+ + L-asparagine + L-glutamate 0.05552573949027911 r_0212 Asparaginyl-tRNA synthetase 1.710863586358636 prot_P38707 + ATP + L-asparagine + tRNA(Asn) --> AMP + Asn-tRNA(Asn) + diphosphate 0.05552573949027911 r_0213 asparaginyl-tRNA synthetase, miotchondrial 1.5617436743674367 prot_P25345 + ATP + L-asparagine + tRNA(Asn) --> AMP + Asn-tRNA(Asn) + diphosphate 0.0 -r_0214 aspartate carbamoyltransferase 0.1632300826005862 prot_P07259 + carbamoyl phosphate + L-aspartate --> H+ + N-carbamoyl-L-aspartate + phosphate 0.031107817482281964 -r_0215 aspartate kinase 0.0711086637298091 prot_P10869 + ATP + L-aspartate --> 4-phospho-L-aspartate + ADP 0.10278208838588898 +r_0214 aspartate carbamoyltransferase 0.1632300826005862 prot_P07259 + carbamoyl phosphate + L-aspartate --> H+ + N-carbamoyl-L-aspartate + phosphate 0.031107817482281988 +r_0215 aspartate kinase 0.0711086637298091 prot_P10869 + ATP + L-aspartate --> 4-phospho-L-aspartate + ADP 0.10278208838588837 r_0216 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.0 -r_0216_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.38517467458609767 +r_0216_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.3851746745860845 r_0217 aspartate transaminase 0.021473880597014924 prot_Q01802 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.0 r_0218 aspartate transaminase 0.0030680788702371438 prot_P23542 + 2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate 0.0 r_0218_REV aspartate transaminase (reversible) 0.019095356550580433 prot_P23542 + L-glutamate + oxaloacetate --> 2-oxoglutarate + L-aspartate 0.0 -r_0219 aspartate-semialdehyde dehydrogenase 26.415673633916466 prot_P13663 + 4-phospho-L-aspartate + H+ + NADPH --> L-aspartate 4-semialdehyde + NADP(+) + phosphate 0.10278208838588898 +r_0219 aspartate-semialdehyde dehydrogenase 26.415673633916466 prot_P13663 + 4-phospho-L-aspartate + H+ + NADPH --> L-aspartate 4-semialdehyde + NADP(+) + phosphate 0.10278208838588837 r_0220 Aspartyl-tRNA synthetase 0.7351388888888889 prot_P04802 + ATP + L-aspartate + tRNA(Asp) --> AMP + Asp-tRNA(Asp) + diphosphate 0.06970438455579828 r_0221 Aspartyl-tRNA synthetase 0.8733912037037037 prot_P15179 + ATP + L-aspartate + tRNA(Asp) --> AMP + Asp-tRNA(Asp) + diphosphate 0.0 r_0222 ATP adenylyltransferase 0.10660011574074074 prot_P22108 + ADP + ATP + H+ --> P(1),P(4)-bis(5'-adenosyl) tetraphosphate + phosphate 0.0 r_0223 ATP adenylyltransferase 0.10559317129629629 prot_P16550 + ADP + GTP + H+ --> P1-(5'-adenosyl),P4-(5'-guanosyl) tetraphosphate + phosphate 0.0 r_0224 ATP adenylyltransferase 0.10559317129629629 prot_P16550 + GDP + GTP + H+ --> P(1),P(4)-bis(5'-guanosyl) tetraphosphate + phosphate 0.0 r_0225 ATP phosphoribosyltransferase 0.8298868312757202 prot_P00498 + ATP + PRPP --> 5-phosphoribosyl-ATP + diphosphate 0.0242344554134714 -r_0226 ATP synthase 0.5394232482136998 prot_P00830 + 0.09548902616935218 prot_P00854 + 0.019105024583592853 prot_P00856 + 0.08835499603456501 prot_P05626 + 0.5769704298154636 prot_P07251 + 0.07486465662145093 prot_P09457 + 0.022127306899204155 prot_P21306 + 0.06500696272775239 prot_P30902 + 0.11272358287031914 prot_P38077 + 0.25461333861919777 prot_P61829 + 0.0356898398095424 prot_P81449 + 0.021946823156143762 prot_P81450 + 0.024722991276672712 prot_P81451 + 0.03712058366362115 prot_Q06405 + 0.05585151467068882 prot_Q12165 + 0.04240055352878791 prot_Q12233 + 0.04636135130831326 prot_Q12349 + ADP + 3.0 H+ + phosphate --> ATP + 2.0 H+ + H2O 19.533080971870007 +r_0226 ATP synthase 0.028401930104729925 prot_P00830 + 0.005027726661784965 prot_P00854 + 0.0010059254484659976 prot_P00856 + 0.004652102834068531 prot_P05626 + 0.03037887943165331 prot_P07251 + 0.0039418040503784385 prot_P09457 + 0.0011650558740993167 prot_P21306 + 0.0034227727815375154 prot_P30902 + 0.005935167482008843 prot_P38077 + 0.013406004044396558 prot_P61829 + 0.0018791558188794555 prot_P81449 + 0.0011555529713742 prot_P81450 + 0.0013017248932914508 prot_P81451 + 0.0019544879204821996 prot_Q06405 + 0.0029407164432997735 prot_Q12165 + 0.002232491020204252 prot_Q12233 + 0.0024410365400081785 prot_Q12349 + ADP + 3.0 H+ + phosphate --> ATP + 2.0 H+ + H2O 18.09981723546289 r_0226_REV ATP synthase (reversible) 0.3805138888888889 prot_P00830 + 0.06735879629629629 prot_P00854 + 0.013476851851851853 prot_P00856 + 0.06232638888888889 prot_P05626 + 0.407 prot_P07251 + 0.05281018518518518 prot_P09457 + 0.015608796296296296 prot_P21306 + 0.045856481481481484 prot_P30902 + 0.0795162037037037 prot_P38077 + 0.17960648148148148 prot_P61829 + 0.025175925925925925 prot_P81449 + 0.015481481481481481 prot_P81450 + 0.017439814814814814 prot_P81451 + 0.026185185185185186 prot_Q06405 + 0.03939814814814815 prot_Q12165 + 0.029909722222222223 prot_Q12233 + 0.03270370370370371 prot_Q12349 + ATP + 2.0 H+ + H2O --> ADP + 3.0 H+ + phosphate 0.0 r_0227_EXP_1 ATPase, plasma membrane 4.61199074074074 prot_P05030 + 0.20837962962962964 prot_P32903 + 0.22444444444444445 prot_P40975 + ATP + H2O --> ADP + H+ + phosphate 0.0 r_0227_EXP_2 ATPase, plasma membrane 4.730185185185185 prot_P19657 + 0.20837962962962964 prot_P32903 + 0.22444444444444445 prot_P40975 + ATP + H2O --> ADP + H+ + phosphate 0.0 -r_0227_EXP_3 ATPase, plasma membrane 0.023208010335917312 prot_P40009 + ATP + H2O --> ADP + H+ + phosphate 3.621025409870066 +r_0227_EXP_3 ATPase, plasma membrane 0.023208010335917312 prot_P40009 + ATP + H2O --> ADP + H+ + phosphate 3.152434378955146 r_0228 beta-1,4 mannosyltransferase 63.94951949233543 prot_P16661 + GDP-alpha-D-mannose + N,N'-diacetylchitobiosyldiphosphodolichol --> beta-D-mannosyldiacetylchitobiosyldiphosphodolichol + GDP + H+ 0.0 r_0229 biotin synthase 0.8370103916866507 prot_P32451 + dethiobiotin + polysulphur --> biotin + 2.0 H+ 0.0 r_0229_REV biotin synthase (reversible) 0.8370103916866507 prot_P32451 + biotin + 2.0 H+ --> dethiobiotin + polysulphur 0.0 @@ -347,13 +347,13 @@ r_0242 C-5 sterol desaturase 24.953439493862604 prot_P32353 + episterol + H+ + N r_0243 C-8 sterol isomerase 11.181301444435384 prot_P32352 + fecosterol --> episterol 0.0 r_0244 C-s24 sterol reductase 1.5624148864343401 prot_P25340 + ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + NADPH --> ergosterol + NADP(+) 0.010694455410100273 r_0249 CAAX farnesyltransferase 4.1518225763666585 prot_P22007 + 3.231511956720494 prot_P29703 + 4-hydroxybenzoate + nonaprenyl diphosphate --> diphosphate + nonaprenyl 4-hydroxybenzoate 0.0 -r_0250_EXP_1 carbamoyl-phosphate synthase (glutamine-hydrolysing) 0.01089245390373571 prot_P07259 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.08745371698939572 +r_0250_EXP_1 carbamoyl-phosphate synthase (glutamine-hydrolysing) 0.01089245390373571 prot_P07259 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.08745371698939575 r_0250_EXP_2 carbamoyl-phosphate synthase (glutamine-hydrolysing) 3.661790780141844 prot_P03965 + 1.34048463356974 prot_P07258 + 2.0 ATP + bicarbonate + H2O + L-glutamine --> 2.0 ADP + carbamoyl phosphate + 2.0 H+ + L-glutamate + phosphate 0.0 r_0252_EXP_1 carnitine O-acetyltransferase 0.016201655041376033 prot_P80235 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 r_0252_EXP_2 carnitine O-acetyltransferase 0.05053501564945227 prot_P40017 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 r_0253 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + (R)-carnitine + acetyl-CoA --> coenzyme A + O-acetylcarnitine 0.0 r_0254 carnitine O-acetyltransferase 0.08348681366191094 prot_P32796 + coenzyme A + O-acetylcarnitine --> (R)-carnitine + acetyl-CoA 0.0 -r_0255 catalase 6.339124460149195e-06 prot_P06115 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0009166123111186748 +r_0255 catalase 6.339124460149195e-06 prot_P06115 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.000916612311082074 r_0256 catalase 5.747447978013349e-06 prot_P15202 + 2.0 hydrogen peroxide --> 2.0 H2O + oxygen 0.0 r_0259 ceramide-1 hydroxylase (24C) 0.035359375 prot_P38992 + ceramide-1 (C24) + H+ + NADPH + oxygen --> ceramide-2 (C24) + H2O + NADP(+) 0.0 r_0260 ceramide-1 hydroxylase (24C) 0.03895920138888889 prot_Q03529 + ceramide-1 (C24) + H+ + NADPH + oxygen --> ceramide-2' (C24) + H2O + NADP(+) 0.0 @@ -372,10 +372,10 @@ r_0271_EXP_2 chitin deacetylase 0.01794357473933983 prot_Q06703 + chitin + H2O - r_0272_EXP_1 chitin synthase 80.72709323101475 prot_P29465 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0 r_0272_EXP_2 chitin synthase 13.190119547029806 prot_P14180 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0068468999999999995 r_0272_EXP_3 chitin synthase 188.53265572369114 prot_P08004 + UDP-N-acetyl-alpha-D-glucosamine --> chitin + H+ + UDP 0.0 -r_0273 choline kinase 7.224074074074074 prot_P20485 + ATP + choline --> ADP + choline phosphate + H+ 0.010068800024351886 -r_0274 choline phosphate cytididyltransferase 0.4121287954621288 prot_P13259 + choline phosphate + CTP + H+ --> CDP-choline + diphosphate 0.010068800024351886 +r_0273 choline kinase 7.224074074074074 prot_P20485 + ATP + choline --> ADP + choline phosphate + H+ 0.010068800024351898 +r_0274 choline phosphate cytididyltransferase 0.4121287954621288 prot_P13259 + choline phosphate + CTP + H+ --> CDP-choline + diphosphate 0.0100688000243519 r_0278 chorismate mutase 0.02288935056940597 prot_P32178 + chorismate --> prephenate 0.08404826945767588 -r_0279 chorismate synthase 0.3336437908496732 prot_P28777 + 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid --> chorismate + phosphate 0.09701220164382707 +r_0279 chorismate synthase 0.3336437908496732 prot_P28777 + 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid --> chorismate + phosphate 0.09701220164382451 r_0280 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 0.0 r_0280_REV cis-aconitate(3-) to isocitrate (reversible) 0.16582750582750583 prot_P19414 + isocitrate --> cis-aconitate + H2O 0.0 r_0281_EXP_1 cis-prenyltransferase step 01 40.954572225982666 prot_P35196 + farnesyl diphosphate + isopentenyl diphosphate --> diphosphate + geranylgeranyl diphosphate 0.0 @@ -420,22 +420,22 @@ r_0298_EXP_1 cis-prenyltransferase step 18 40.954572225982666 prot_P35196 + icos r_0298_EXP_2 cis-prenyltransferase step 18 30.078354060470264 prot_Q03175 + icosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + henicosaprenyl diphosphate 0.0 r_0299_EXP_1 cis-prenyltransferase step 19 40.954572225982666 prot_P35196 + henicosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + docosaprenyl diphosphate 0.0 r_0299_EXP_2 cis-prenyltransferase step 19 30.078354060470264 prot_Q03175 + henicosaprenyl diphosphate + isopentenyl diphosphate --> diphosphate + docosaprenyl diphosphate 0.0 -r_0300_EXP_1 citrate synthase 0.10489895415585436 prot_P00890 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 2.50194742075915 +r_0300_EXP_1 citrate synthase 0.10489895415585436 prot_P00890 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 2.2948399936839543 r_0300_EXP_2 citrate synthase 0.10578556263269638 prot_P43635 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.0 r_0301 citrate synthase, peroxisomal 1.275124007936508 prot_P08679 + acetyl-CoA + H2O + oxaloacetate --> citrate + coenzyme A + H+ 0.0 r_0302 citrate to cis-aconitate(3-) 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 0.0 r_0302_REV citrate to cis-aconitate(3-) (reversible) 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> citrate 0.0 -r_0303 citrate to cis-aconitate(3-), cytoplasmic 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 2.50194742075915 +r_0303 citrate to cis-aconitate(3-), cytoplasmic 0.16582750582750583 prot_P19414 + citrate --> cis-aconitate + H2O 2.2948399936839543 r_0303_REV citrate to cis-aconitate(3-), cytoplasmic (reversible) 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> citrate 0.0 r_0304 coproporphyrinogen oxidase (O2 required) 616.2091503267974 prot_P11353 + coproporphyrinogen III + 2.0 H+ + oxygen --> 2.0 carbon dioxide + 2.0 H2O + protoporphyrinogen 2.899999992678204e-07 r_0306_EXP_1 CTP synthase (glutamine) 0.5634796238244514 prot_P28274 + ATP + H2O + L-glutamine + UTP --> ADP + CTP + 2.0 H+ + L-glutamate + phosphate 0.0 r_0306_EXP_2 CTP synthase (glutamine) 0.5617467781260884 prot_P38627 + ATP + H2O + L-glutamine + UTP --> ADP + CTP + 2.0 H+ + L-glutamate + phosphate 0.0 r_0307_EXP_1 CTP synthase (NH3) 0.5634796238244514 prot_P28274 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.0 -r_0307_EXP_2 CTP synthase (NH3) 0.5617467781260884 prot_P38627 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.014290109378625914 +r_0307_EXP_2 CTP synthase (NH3) 0.5617467781260884 prot_P38627 + ammonium + ATP + UTP --> ADP + CTP + 2.0 H+ + phosphate 0.014290109378625918 r_0308_EXP_1 cystathionine b-lyase 11.285409035409035 prot_P43623 + H2O + L-cystathionine --> ammonium + L-homocysteine + pyruvate 0.0 r_0308_EXP_2 cystathionine b-lyase 15.820512820512821 prot_P53101 + H2O + L-cystathionine --> ammonium + L-homocysteine + pyruvate 0.0 -r_0309 cystathionine beta-synthase 0.7237984496124031 prot_P32582 + L-homocysteine + L-serine --> H2O + L-cystathionine 0.010947644902257605 -r_0310 cystathionine g-lyase 6.5288520564763655 prot_P31373 + H2O + L-cystathionine --> 2-oxobutanoate + ammonium + L-cysteine 0.010947644902257605 +r_0309 cystathionine beta-synthase 0.7237984496124031 prot_P32582 + L-homocysteine + L-serine --> H2O + L-cystathionine 0.010947644902256994 +r_0310 cystathionine g-lyase 6.5288520564763655 prot_P31373 + H2O + L-cystathionine --> 2-oxobutanoate + ammonium + L-cysteine 0.010947644902256994 r_0311 cystathionine gamma-synthase 0.16609504132231406 prot_P47164 + L-cysteine + O-acetyl-L-homoserine --> acetate + H+ + L-cystathionine 0.0 r_0312 cysteine synthase 0.05827586206896552 prot_P06106 + hydrogen sulfide + O-acetyl-L-serine --> acetate + L-cysteine 0.0 r_0313 cysteinyl-tRNA synthetase 0.1712245696400626 prot_P53852 + ATP + L-cysteine + tRNA(Cys) --> AMP + Cys-tRNA(Cys) + diphosphate 0.010892254900484382 @@ -459,7 +459,7 @@ r_0330 deoxyguanylate kinase (dGMP:ATP) 0.06369444444444444 prot_P15454 + ATP + r_0330_REV deoxyguanylate kinase (dGMP:ATP) (reversible) 0.014549492385786802 prot_P15454 + ADP + dGDP --> ATP + dGMP 0.0006960000330582252 r_0331 deoxyhypusine synthase, cytosolic/mitochondrial 66.19135802469135 prot_P38791 + H2O + spermidine + ubiquinone-6 --> 4-aminobutanal + trimethylenediamine + ubiquinol-6 0.0 r_0332 deoxyribokinase 0.214529735759604 prot_P25332 + 2-deoxy-D-ribose + ATP --> 2-deoxy-D-ribose 5-phosphate + ADP + H+ 0.0 -r_0334 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 0.0 +r_0334 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 0.0004977833232718831 r_0335 dethiobiotin synthase 0.18895365572826714 prot_P53630 + 7,8-diaminononanoate + ATP + carbon dioxide --> ADP + dethiobiotin + 3.0 H+ + phosphate 0.0 r_0335_REV dethiobiotin synthase (reversible) 0.14884920634920634 prot_P53630 + ADP + dethiobiotin + 3.0 H+ + phosphate --> 7,8-diaminononanoate + ATP + carbon dioxide 0.0 r_0340 dihydroceramidase 2.6755547192301745 prot_Q02896 + lignoceric acid + sphinganine --> ceramide-1 (C24) + H2O 0.0 @@ -474,10 +474,10 @@ r_0346 dihydrofolate synthase 1.4510179534077177 prot_Q12676 + 7,8-dihydropteroa r_0347 dihydroneopterin aldolase 25.866666666666667 prot_P53848 + 7,8-dihydroneopterin --> 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + glycolaldehyde 1.83860007382311e-05 r_0348 dihydroneopterin monophosphate dephosphorylase 1.3136097495034373 prot_Q12154 + 7,8-dihydroneopterin 3'-phosphate + H2O --> 7,8-dihydroneopterin + phosphate 0.0 r_0349 dihydroorotase 5.893713450292398 prot_P20051 + (S)-dihydroorotate + H2O --> H+ + N-carbamoyl-L-aspartate 0.0 -r_0349_REV dihydroorotase (reversible) 0.17974406991260924 prot_P20051 + H+ + N-carbamoyl-L-aspartate --> (S)-dihydroorotate + H2O 0.031107817482281964 +r_0349_REV dihydroorotase (reversible) 0.17974406991260924 prot_P20051 + H+ + N-carbamoyl-L-aspartate --> (S)-dihydroorotate + H2O 0.031107817482281988 r_0350 dihydropteroate synthase 237.30886850152908 prot_P53848 + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol + 4-aminobenzoate --> 7,8-dihydropteroate + H2O 1.83860007382311e-05 r_0351 dihydropteroate synthase 237.30886850152908 prot_P53848 + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate + 4-aminobenzoate --> 7,8-dihydropteroate + diphosphate 0.0 -r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.23036133098798006 prot_P39522 + (R)-2,3-dihydroxy-3-methylbutanoate --> 3-methyl-2-oxobutanoate + H2O 0.19642217467935663 +r_0352 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate) 0.23036133098798006 prot_P39522 + (R)-2,3-dihydroxy-3-methylbutanoate --> 3-methyl-2-oxobutanoate + H2O 0.19642217468055667 r_0353 dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate) 1.419625112917796 prot_P39522 + (2R,3R)-2,3-dihydroxy-3-methylpentanoate --> (S)-3-methyl-2-oxopentanoate + H2O 0.07699219285051538 r_0354_EXP_1 dihydroxyacetone kinase 0.7185562956795263 prot_P43550 + ATP + glycerone --> ADP + dihydroxyacetone phosphate + H+ 0.0 r_0354_EXP_2 dihydroxyacetone kinase 0.719388935146637 prot_P54838 + ATP + glycerone --> ADP + dihydroxyacetone phosphate + H+ 0.0 @@ -498,7 +498,7 @@ r_0364_EXP_1 dUTP diphosphatase 0.006082204603017289 prot_P47119 + dUTP + H2O -- r_0364_EXP_2 dUTP diphosphatase 0.4429108796296296 prot_P33317 + dUTP + H2O --> diphosphate + dUMP + H+ 0.0 r_0365 endopolygalacturonase 1.7035361842105263 prot_P47180 + H2O + pectin --> D-galacturonate 0.0 r_0366_EXP_1 enolase 0.05715942028985507 prot_P0CX11 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 -r_0366_EXP_2 enolase 0.056541062801932364 prot_P00924 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 9.716788442964297 +r_0366_EXP_2 enolase 0.056541062801932364 prot_P00924 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 9.748930572797638 r_0366_EXP_3 enolase 0.18354460093896713 prot_P00925 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 r_0366_EXP_4 enolase 0.057141304347826084 prot_P42222 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 r_0366_EXP_5 enolase 0.05715942028985507 prot_P0CX10 + 2-phospho-D-glyceric acid --> H2O + phosphoenolpyruvate 0.0 @@ -524,40 +524,40 @@ r_0402 fatty-acid--CoA ligase (hexadecanoate) 799.2145593869732 prot_P39518 + AT r_0402_REV fatty-acid--CoA ligase (hexadecanoate) (reversible) 33.739859453840296 prot_P39518 + AMP + diphosphate + palmitoyl-CoA --> ATP + coenzyme A + palmitate 0.0 r_0410 fatty-acid--CoA ligase (octanoate) 799.2145593869732 prot_P39518 + ATP + coenzyme A + octanoate --> AMP + diphosphate + octanoyl-CoA 0.0 r_0410_REV fatty-acid--CoA ligase (octanoate) (reversible) 33.739859453840296 prot_P39518 + AMP + diphosphate + octanoyl-CoA --> ATP + coenzyme A + octanoate 0.0 -r_0412 fatty-acid--CoA ligase (tetradecanoate) 799.2145593869732 prot_P39518 + ATP + coenzyme A + myristate --> AMP + diphosphate + myristoyl-CoA 0.0 +r_0412 fatty-acid--CoA ligase (tetradecanoate) 799.2145593869732 prot_P39518 + ATP + coenzyme A + myristate --> AMP + diphosphate + myristoyl-CoA 3.922891305596643e-05 r_0412_REV fatty-acid--CoA ligase (tetradecanoate) (reversible) 33.739859453840296 prot_P39518 + AMP + diphosphate + myristoyl-CoA --> ATP + coenzyme A + myristate 0.0 r_0436 ferrochelatase 8.096586782861293 prot_P16622 + iron(2+) + protoporphyrin --> ferroheme b + 2.0 H+ 2.899999992678204e-07 r_0437_EXP_1 ferrocytochrome-c:hydrogen-peroxide oxidoreductase 0.003481111111111111 prot_P00045 + 0.011209166666666666 prot_P00431 + 2.0 ferrocytochrome c + hydrogen peroxide --> 2.0 ferricytochrome c + 2.0 H2O 0.0 r_0437_EXP_2 ferrocytochrome-c:hydrogen-peroxide oxidoreductase 0.003383888888888889 prot_P00044 + 0.011209166666666666 prot_P00431 + 2.0 ferrocytochrome c + hydrogen peroxide --> 2.0 ferricytochrome c + 2.0 H2O 0.0 -r_0438_EXP_1 ferrocytochrome-c:oxygen oxidoreductase 0.0025292407050374562 prot_P00045 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003470743090051798 prot_P00425 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_2 ferrocytochrome-c:oxygen oxidoreductase 0.0025292407050374562 prot_P00045 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003459239202389243 prot_P00424 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_3 ferrocytochrome-c:oxygen oxidoreductase 0.002458602798337559 prot_P00044 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003470743090051798 prot_P00425 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 -r_0438_EXP_4 ferrocytochrome-c:oxygen oxidoreductase 0.002458602798337559 prot_P00044 + 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.003459239202389243 prot_P00424 + 0.0035000073656846122 prot_P00427 + 0.003459844670160957 prot_P04037 + 0.001797633814217094 prot_P04039 + 0.0014052906981468086 prot_P07255 + 0.0013990341978391036 prot_P10174 + 0.0030315771329690096 prot_P32799 + 0.0019754395165102632 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 15.514666010858877 -r_0438_EXP_5 ferrocytochrome-c:oxygen oxidoreductase 0.01186676468040156 prot_P00401 + 0.005765465944845596 prot_P00410 + 0.00612733384973964 prot_P00420 + 0.0014052906981468086 prot_P07255 + 0.006870848273403699 prot_P19516 + 0.003495163623510905 prot_P38824 + 0.0028410566074698585 prot_P47081 + 0.007194975353860941 prot_P53239 + 0.004794901106789011 prot_Q04935 + 0.0022412398682924474 prot_Q3E731 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 16.505079069216265 -r_0439_EXP_1 ubiquinol:ferricytochrome c reductase 0.011983406387337664 prot_P00045 + 0.01650156750927913 prot_P00127 + 0.013927410950492583 prot_P00128 + 0.041744940093010934 prot_P00163 + 0.03256422793814109 prot_P07143 + 0.04802924800695788 prot_P07256 + 0.03870605839025327 prot_P07257 + 0.022342187219928544 prot_P08067 + 0.010494564722393141 prot_P08525 + 0.007148734930716276 prot_P22289 + 0.008216837782188999 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 4.821359486150767 -r_0439_EXP_2 ubiquinol:ferricytochrome c reductase 0.01164872778571237 prot_P00044 + 0.01650156750927913 prot_P00127 + 0.013927410950492583 prot_P00128 + 0.041744940093010934 prot_P00163 + 0.03256422793814109 prot_P07143 + 0.04802924800695788 prot_P07256 + 0.03870605839025327 prot_P07257 + 0.022342187219928544 prot_P08067 + 0.010494564722393141 prot_P08525 + 0.007148734930716276 prot_P22289 + 0.008216837782188999 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 11.188513053886807 -r_0440 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 2.8999999267398372e-06 +r_0438_EXP_1 ferrocytochrome-c:oxygen oxidoreductase 0.0010737358074137757 prot_P00045 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0014734307915811285 prot_P00425 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_2 ferrocytochrome-c:oxygen oxidoreductase 0.0010737358074137757 prot_P00045 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.001468547058655611 prot_P00424 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_3 ferrocytochrome-c:oxygen oxidoreductase 0.0010437479736605981 prot_P00044 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0014734307915811285 prot_P00425 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0438_EXP_4 ferrocytochrome-c:oxygen oxidoreductase 0.0010437479736605981 prot_P00044 + 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.001468547058655611 prot_P00424 + 0.001485854322707445 prot_P00427 + 0.0014688040972306382 prot_P04037 + 0.0007631475292558651 prot_P04039 + 0.0005965865326382158 prot_P07255 + 0.0005939304673629344 prot_P10174 + 0.001286992145161373 prot_P32799 + 0.0008386311907888635 prot_Q01519 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 29.646908761141674 +r_0438_EXP_5 ferrocytochrome-c:oxygen oxidoreductase 0.005037784711483816 prot_P00401 + 0.0024476069909343547 prot_P00410 + 0.002601230379275633 prot_P00420 + 0.0005965865326382158 prot_P07255 + 0.0029168737494090794 prot_P19516 + 0.001483798014107227 prot_P38824 + 0.0012061106735528025 prot_P47081 + 0.00305447506657366 prot_P53239 + 0.0020355741551656946 prot_Q04935 + 0.0009514711252258203 prot_Q3E731 + ferrocytochrome c + 1.266 H+ + 0.25 oxygen --> ferricytochrome c + 0.633 H+ + 0.5 H2O 0.0 +r_0439_EXP_1 ubiquinol:ferricytochrome c reductase 0.0023972378816698543 prot_P00045 + 0.003301079965207204 prot_P00127 + 0.002786129089253226 prot_P00128 + 0.00835092698389556 prot_P00163 + 0.006514358128013637 prot_P07143 + 0.009608080459664334 prot_P07256 + 0.007743009493634883 prot_P07257 + 0.004469475191925961 prot_P08067 + 0.0020994003950946896 prot_P08525 + 0.0014300790299524282 prot_P22289 + 0.001643749211393956 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 0.0 +r_0439_EXP_2 ubiquinol:ferricytochrome c reductase 0.002330286616222643 prot_P00044 + 0.003301079965207204 prot_P00127 + 0.002786129089253226 prot_P00128 + 0.00835092698389556 prot_P00163 + 0.006514358128013637 prot_P07143 + 0.009608080459664334 prot_P07256 + 0.007743009493634883 prot_P07257 + 0.004469475191925961 prot_P08067 + 0.0020994003950946896 prot_P08525 + 0.0014300790299524282 prot_P22289 + 0.001643749211393956 prot_P37299 + 2.0 ferricytochrome c + 1.266 H+ + ubiquinol-6 --> 2.0 ferrocytochrome c + 2.532 H+ + ubiquinone-6 14.823454380570837 +r_0440 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 0.0 r_0441 FMN reductase 0.10556051587301588 prot_Q07923 + FMN + 2.0 H+ + NADH --> FMNH2 + NAD 0.0 r_0442 FMN reductase 0.10556051587301588 prot_Q07923 + FMN + 2.0 H+ + NADPH --> FMNH2 + NADP(+) 0.0 r_0443 formaldehyde dehydrogenase 8.906684027777779 prot_P32771 + formaldehyde + glutathione + NAD --> H+ + NADH + S-formylglutathione 0.0 r_0445 formate dehydrogenase 0.012874691358024692 prot_Q08911 + formate + NAD --> carbon dioxide + NADH 0.0 -r_0446 formate-tetrahydrofolate ligase 0.3982132433666004 prot_P07245 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.015305821462242596 +r_0446 formate-tetrahydrofolate ligase 0.3982132433666004 prot_P07245 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.015305821462187293 r_0446_REV formate-tetrahydrofolate ligase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.0 r_0447 formate-tetrahydrofolate ligase 0.42978473739580797 prot_P09440 + ATP + formate + THF --> 10-formyl-THF + ADP + phosphate 0.0 r_0447_REV formate-tetrahydrofolate ligase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + ADP + phosphate --> ATP + formate + THF 0.0 r_0448_EXP_1 fructose-2,6-bisphosphate 2-phosphatase 5.915698747876994 prot_Q06137 + beta-D-fructose 2,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 r_0448_EXP_2 fructose-2,6-bisphosphate 2-phosphatase 146.09722222222223 prot_P32604 + beta-D-fructose 2,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 r_0449 fructose-bisphosphatase 0.15249083373186673 prot_P09201 + D-fructose 1,6-bisphosphate + H2O --> D-fructose 6-phosphate + phosphate 0.0 -r_0450 fructose-bisphosphate aldolase 0.166213415970673 prot_P14540 + D-fructose 1,6-bisphosphate --> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate 5.009728838904098 +r_0450 fructose-bisphosphate aldolase 0.166213415970673 prot_P14540 + D-fructose 1,6-bisphosphate --> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate 5.041870968737412 r_0450_REV fructose-bisphosphate aldolase (reversible) 0.33864102564102566 prot_P14540 + dihydroxyacetone phosphate + glyceraldehyde 3-phosphate --> D-fructose 1,6-bisphosphate 0.0 -r_0451 fumarase 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 2.104944131511068 +r_0451 fumarase 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 1.8972578057883522 r_0451_REV fumarase (reversible) 0.014265163714439076 prot_P08417 + (S)-malate --> fumarate + H2O 0.0 -r_0452 fumarase, cytoplasmic 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.12605464467184935 +r_0452 fumarase, cytoplasmic 0.014265163714439076 prot_P08417 + fumarate + H2O --> (S)-malate 0.12659431440661623 r_0452_REV fumarase, cytoplasmic (reversible) 0.014265163714439076 prot_P08417 + (S)-malate --> fumarate + H2O 0.0 -r_0453 dihydoorotic acid dehydrogenase 1.1372875816993464 prot_P28272 + (S)-dihydroorotate + fumarate --> orotate + succinate 0.031107817482281964 +r_0453 dihydoorotic acid dehydrogenase 1.1372875816993464 prot_P28272 + (S)-dihydroorotate + fumarate --> orotate + succinate 0.031107817482281988 r_0454 fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.0 r_0454_REV fumarate reductase (reversible) 0.9170995670995671 prot_P32614 + FAD + H+ + succinate --> FADH2 + fumarate 0.0 -r_0455 soluble fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 0.0 +r_0455 soluble fumarate reductase 0.9170995670995671 prot_P32614 + FADH2 + fumarate --> FAD + H+ + succinate 2.8999999267398372e-06 r_0455_REV soluble fumarate reductase (reversible) 0.9170995670995671 prot_P32614 + FAD + H+ + succinate --> FADH2 + fumarate 0.0 r_0457 g-glutamyltransferase 17.374169040835707 prot_Q05902 + glutathione + L-alanine --> L-cysteinylglycine + L-gamma-glutamyl-L-alanine 0.0 r_0458 galactokinase 0.7217737917289487 prot_P04385 + ATP + D-galactose --> ADP + alpha-D-galactose 1-phosphate + H+ 0.0 @@ -568,19 +568,19 @@ r_0462 geranyltranstransferase 10.222979797979797 prot_P08524 + geranyl diphosph r_0463 glucan 1,4-alpha-glucosidase 44.78465926163774 prot_Q06625 + glycogen + H2O --> D-glucose 0.0 r_0464 glucan 1,4-alpha-glucosidase, vacuole 0.05205199864498645 prot_P08019 + glycogen + H2O --> D-glucose 0.0 r_0465 glucosamine-6-phosphate deaminase 0.1225001911377612 prot_standard + alpha-D-glucosamine 6-phosphate + H2O --> ammonium + D-fructose 6-phosphate 0.0 -r_0466 glucose 6-phosphate dehydrogenase 0.025250210703750525 prot_P11412 + D-glucose 6-phosphate + NADP(+) --> 6-O-phosphono-D-glucono-1,5-lactone + H+ + NADPH 0.1712230135015525 -r_0467 glucose-6-phosphate isomerase 0.024857664233576642 prot_P12709 + D-glucose 6-phosphate --> D-fructose 6-phosphate 5.206548319556482 +r_0466 glucose 6-phosphate dehydrogenase 0.025250210703750525 prot_P11412 + D-glucose 6-phosphate + NADP(+) --> 6-O-phosphono-D-glucono-1,5-lactone + H+ + NADPH 0.0747966240017505 +r_0467 glucose-6-phosphate isomerase 0.024857664233576642 prot_P12709 + D-glucose 6-phosphate --> D-fructose 6-phosphate 5.302974709056285 r_0467_REV glucose-6-phosphate isomerase (reversible) 0.024857664233576642 prot_P12709 + D-fructose 6-phosphate --> D-glucose 6-phosphate 0.0 r_0468 glutamate 5-kinase 1.0234809027777778 prot_P32264 + ATP + L-glutamate --> ADP + L-gamma-glutamyl phosphate 0.018106846428318973 -r_0469 glutamate decarboxylase 34.13511276639768 prot_Q04792 + H+ + L-glutamate --> carbon dioxide + gamma-aminobutyrate 0.0 +r_0469 glutamate decarboxylase 34.13511276639768 prot_Q04792 + H+ + L-glutamate --> carbon dioxide + gamma-aminobutyrate 0.0005396697347794297 r_0470 glutamate dehydrogenase (NAD) 1.4390277777777778 prot_P33327 + H2O + L-glutamate + NAD --> 2-oxoglutarate + ammonium + H+ + NADH 0.0 r_0471_EXP_1 glutamate dehydrogenase (NADP) 0.5307169380898228 prot_P39708 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 0.0 -r_0471_EXP_2 glutamate dehydrogenase (NADP) 0.5301073734280234 prot_P07262 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 1.6025321366524923 +r_0471_EXP_2 glutamate dehydrogenase (NADP) 0.5301073734280234 prot_P07262 + 2-oxoglutarate + ammonium + H+ + NADPH --> H2O + L-glutamate + NADP(+) 1.602532136652525 r_0472 glutamate synthase (NADH2) 0.9448492063492063 prot_Q12680 + 2-oxoglutarate + H+ + L-glutamine + NADH --> 2.0 L-glutamate + NAD 0.0 r_0473 glutamate-5-semialdehyde dehydrogenase 0.2646166013940106 prot_P54885 + H+ + L-gamma-glutamyl phosphate + NADPH --> L-glutamic 5-semialdehyde + NADP(+) + phosphate 0.018106846428318973 r_0475_EXP_1 glutaminase 0.0011171565228214292 prot_P43544 + H2O + L-glutamine --> ammonium + L-glutamate 0.0 r_0475_EXP_2 glutaminase 0.0011205348411301363 prot_P53823 + H2O + L-glutamine --> ammonium + L-glutamate 0.0 -r_0476 glutamine synthetase 0.029297138047138047 prot_P32288 + ammonium + ATP + L-glutamate --> ADP + H+ + L-glutamine + phosphate 0.30303584875388034 +r_0476 glutamine synthetase 0.029297138047138047 prot_P32288 + ammonium + ATP + L-glutamate --> ADP + H+ + L-glutamine + phosphate 0.3030358487538743 r_0477 glutamine-fructose-6-phosphate transaminase 0.6263458528951487 prot_P14742 + D-fructose 6-phosphate + L-glutamine --> alpha-D-glucosamine 6-phosphate + L-glutamate 0.0068468999999999995 r_0478 glutaminyl-tRNA synthetase 15.369603878657363 prot_P13188 + ATP + L-glutamine + tRNA(Gln) --> AMP + diphosphate + Gln-tRNA(Gln) 0.040936496364394344 r_0479 glutamyl-tRNA synthetase 4.974688861932783 prot_P46655 + ATP + L-glutamate + tRNA(Glu) --> AMP + diphosphate + Glu-tRNA(Glu) 0.08598132048472351 @@ -600,7 +600,7 @@ r_0484 glutathione peroxidase, mitochondria 1.0350179133060056 prot_Q02784 + 2.0 r_0485 glutathione synthetase 0.2818939393939394 prot_Q08220 + ATP + L-gamma-glutamyl-L-cysteine + L-glycine --> ADP + glutathione + H+ + phosphate 2.9e-07 r_0486_EXP_1 glyceraldehyde-3-phosphate dehydrogenase 1.091178266178266 prot_P00359 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 0.0 r_0486_EXP_2 glyceraldehyde-3-phosphate dehydrogenase 0.1416581138487952 prot_P00360 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 1.5901872085896402 -r_0486_EXP_3 glyceraldehyde-3-phosphate dehydrogenase 0.5962574850299401 prot_P00358 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 8.38047952014692 +r_0486_EXP_3 glyceraldehyde-3-phosphate dehydrogenase 0.5962574850299401 prot_P00358 + glyceraldehyde 3-phosphate + NAD + phosphate --> 1,3-bisphospho-D-glycerate + H+ + NADH 8.41262164998031 r_0486_REV_EXP_1 glyceraldehyde-3-phosphate dehydrogenase (reversible) 1.091178266178266 prot_P00359 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 r_0486_REV_EXP_2 glyceraldehyde-3-phosphate dehydrogenase (reversible) 0.3424329501915709 prot_P00360 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 r_0486_REV_EXP_3 glyceraldehyde-3-phosphate dehydrogenase (reversible) 0.5962574850299401 prot_P00358 + 1,3-bisphospho-D-glycerate + H+ + NADH --> glyceraldehyde 3-phosphate + NAD + phosphate 0.0 @@ -608,20 +608,20 @@ r_0487 glycerol dehydrogenase (NADP-dependent) 18.04475308641975 prot_P14065 + g r_0488 glycerol kinase 0.013277445109780439 prot_P32190 + ATP + glycerol --> ADP + glycerol 3-phosphate + H+ 0.0 r_0489_EXP_1 glycerol-3-phosphatase 0.6923038630027878 prot_P40106 + glycerol 3-phosphate + H2O --> glycerol + phosphate 0.0 r_0489_EXP_2 glycerol-3-phosphatase 0.6956142970927918 prot_P41277 + glycerol 3-phosphate + H2O --> glycerol + phosphate 0.0 -r_0490 glycerol-3-phosphate dehydrogenase (fad) 0.6038455121788456 prot_P32191 + FAD + glycerol 3-phosphate + H+ --> dihydroxyacetone phosphate + FADH2 0.0 -r_0491_EXP_1 glycerol-3-phosphate dehydrogenase (NAD) 0.10538102261553589 prot_Q00055 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.02016935957079157 +r_0490 glycerol-3-phosphate dehydrogenase (fad) 0.6038455121788456 prot_P32191 + FAD + glycerol 3-phosphate + H+ --> dihydroxyacetone phosphate + FADH2 2.8999999267398372e-06 +r_0491_EXP_1 glycerol-3-phosphate dehydrogenase (NAD) 0.10538102261553589 prot_Q00055 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.02017225957071831 r_0491_EXP_2 glycerol-3-phosphate dehydrogenase (NAD) 0.1214896755162242 prot_P41911 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.0 r_0492 glycerol-3-phosphate dehydrogenase (NAD) 0.1214896755162242 prot_P41911 + dihydroxyacetone phosphate + H+ + NADH --> glycerol 3-phosphate + NAD 0.0 r_0497 glycerophosphodiester phosphodiesterase (glycerophosphocholine) 0.174260101010101 prot_Q02979 + H2O + sn-glycero-3-phosphocholine --> choline + glycerol 3-phosphate + H+ 0.0 -r_0499 glycinamide ribotide transformylase 0.1634722222222222 prot_P04161 + 10-formyl-THF + 5-phospho-ribosyl-glycineamide --> 5'-phosphoribosyl-N-formylglycineamide + H+ + THF 0.02969723651725126 +r_0499 glycinamide ribotide transformylase 0.1634722222222222 prot_P04161 + 10-formyl-THF + 5-phospho-ribosyl-glycineamide --> 5'-phosphoribosyl-N-formylglycineamide + H+ + THF 0.029697236517247882 r_0500 glycine C-acetyltransferase 0.062476381011109826 prot_standard + coenzyme A + L-2-amino-3-oxobutanoate --> acetyl-CoA + L-glycine 0.0 r_0501 glycine cleavage system 0.17131712790948955 prot_P09624 + 0.05961049407152449 prot_P39726 + 0.14105353380868527 prot_P48015 + 0.3630330791773559 prot_P49095 + L-glycine + NAD + THF --> 5,10-methylenetetrahydrofolate + ammonium + carbon dioxide + NADH 0.0 -r_0502 glycine hydroxymethyltransferase 0.0226640625 prot_P37291 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 0.13390986926763343 +r_0502 glycine hydroxymethyltransferase 0.0226640625 prot_P37291 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 0.13390986926768197 r_0502_REV glycine hydroxymethyltransferase (reversible) 63.06521739130435 prot_P37291 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF 0.0 -r_0503 glycine hydroxymethyltransferase 0.023301215277777777 prot_P37292 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 5.5080207323715874e-05 -r_0503_REV glycine hydroxymethyltransferase (reversible) 64.83816425120773 prot_P37292 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF -1.9794449506960392e-08 +r_0503 glycine hydroxymethyltransferase 0.023301215277777777 prot_P37292 + L-serine + THF --> 5,10-methylenetetrahydrofolate + H2O + L-glycine 5.508020732310547e-05 +r_0503_REV glycine hydroxymethyltransferase (reversible) 64.83816425120773 prot_P37292 + 5,10-methylenetetrahydrofolate + H2O + L-glycine --> L-serine + THF -1.9794449506741027e-08 r_0504 glycine-cleavage complex (lipoamide) 0.023116760828625234 prot_P09624 + 0.00804357130628317 prot_P39726 + 0.019033127889060093 prot_P48015 + 0.048986046909775725 prot_P49095 + H+ + L-glycine + lipoamide --> carbon dioxide + S(8)-aminomethyldihydrolipoamide 0.0 -r_0505_EXP_1 glycine-cleavage complex (lipoamide) 0.016688295637127672 prot_P09624 + 0.005806760598195526 prot_P39726 + 0.013740266963292547 prot_P48015 + 0.0353636756890372 prot_P49095 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 2.1049464515110623 +r_0505_EXP_1 glycine-cleavage complex (lipoamide) 0.016688295637127672 prot_P09624 + 0.005806760598195526 prot_P39726 + 0.013740266963292547 prot_P48015 + 0.0353636756890372 prot_P49095 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 1.8967986713782037 r_0505_EXP_2 glycine-cleavage complex (lipoamide) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + dihydrolipoamide + NAD --> H+ + lipoamide + NADH 0.0 r_0506 glycine-cleavage complex (lipoylprotein) 0.04357695209331861 prot_P09624 + 0.015162778387145652 prot_P39726 + 0.0358789757940712 prot_P48015 + 0.09234263551254228 prot_P49095 + L-glycine + lipoylprotein --> carbon dioxide + S(8)-aminomethyldihydrolipoylprotein 0.0 r_0507 glycine-cleavage complex (lipoylprotein) 0.2838103427329358 prot_P09624 + 0.0987529674315879 prot_P39726 + 0.23367454417683617 prot_P48015 + 0.6014141369399599 prot_P49095 + H+ + S(8)-aminomethyldihydrolipoylprotein + THF --> 5,10-methylenetetrahydrofolate + ammonium + dihydrolipoylprotein 0.0 @@ -634,7 +634,7 @@ r_0510_EXP_4 glycogen (starch) synthase 18.96007470955954 prot_P27472 + 16.50835 r_0511 glycogen phosphorylase 0.568069306930693 prot_P06738 + glycogen + phosphate --> D-glucose 1-phosphate 0.0 r_0512_EXP_1 glycyl-tRNA synthetase 29.750380517503807 prot_P38088 + ATP + L-glycine + tRNA(Gly) --> AMP + diphosphate + Gly-tRNA(Gly) 0.0 r_0512_EXP_2 glycyl-tRNA synthetase 1.2407058001397624 prot_Q06817 + ATP + L-glycine + tRNA(Gly) --> AMP + diphosphate + Gly-tRNA(Gly) 0.08228720510224655 -r_0514 GMP synthase 0.0098038624019312 prot_P38625 + ATP + H2O + L-glutamine + xanthosine-5-phosphate --> AMP + diphosphate + GMP + 2.0 H+ + L-glutamate 0.01391948728321371 +r_0514 GMP synthase 0.0098038624019312 prot_P38625 + ATP + H2O + L-glutamine + xanthosine-5-phosphate --> AMP + diphosphate + GMP + 2.0 H+ + L-glutamate 0.013919487283219508 r_0518 GPI-anchor assembly, step 2 149.73523909383033 prot_P23797 + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O --> 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate + H+ 0.0 r_0518_REV GPI-anchor assembly, step 2 (reversible) 60.09087553078704 prot_P23797 + 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate + H+ --> 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O 0.0 r_0519 GPI-anchor assembly, step 5 1.0741619906421145 prot_P25580 + 1.0571943419782979 prot_P47088 + 6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol + dolichyl D-mannosyl phosphate --> 6-O-[alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + dolichyl phosphate 0.0 @@ -650,10 +650,10 @@ r_0523_EXP_2 GPI-anchor assembly, step 9 0.03254362265000563 prot_Q07830 + 6-O-{ r_0523_REV_EXP_1 GPI-anchor assembly, step 9 (reversible) 0.007109647641562535 prot_Q06636 + 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone --> 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone 0.0 r_0523_REV_EXP_2 GPI-anchor assembly, step 9 (reversible) 0.03254362265000563 prot_Q07830 + 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol + diglyceride backbone --> 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol + phosphatidylethanolamine backbone 0.0 r_0524 GTP cyclohydrolase I 197.7849002849003 prot_P51601 + GTP + H2O --> 7,8-dihydroneopterin 3'-triphosphate + formate + H+ 1.83860007382311e-05 -r_0525 GTP cyclohydrolase II 0.024647633744855967 prot_P38066 + GTP + 3.0 H2O --> 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + diphosphate + formate + 2.0 H+ 0.00028999999161897003 +r_0525 GTP cyclohydrolase II 0.024647633744855967 prot_P38066 + GTP + 3.0 H2O --> 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + diphosphate + formate + 2.0 H+ 0.00028999999162475826 r_0526 guanine deaminase 1.7229712858926343 prot_Q07729 + guanine + H+ + H2O --> 9H-xanthine + ammonium 0.0 r_0527 guanine phosphoribosyltransferase 0.09123207301173403 prot_Q04178 + guanine + PRPP --> diphosphate + GMP 0.0 -r_0528 guanylate kinase 0.014549492385786802 prot_P15454 + ATP + GMP --> ADP + GDP 0.001004386025415414 +r_0528 guanylate kinase 0.014549492385786802 prot_P15454 + ATP + GMP --> ADP + GDP 0.0010043860254212115 r_0529 guanylate kinase (GMP:dATP) 0.014549492385786802 prot_P15454 + dATP + GMP --> dADP + GDP 0.0 r_0529_REV guanylate kinase (GMP:dATP) (reversible) 0.014549492385786802 prot_P15454 + dADP + GDP --> dATP + GMP 0.0 r_0530_EXP_1 heme O monooxygenase 0.5821949882086304 prot_P40086 + heme o + NADH + oxygen --> H2O + heme a + NAD 2.899999992678204e-07 @@ -686,10 +686,10 @@ r_0543_EXP_2 homocitrate synthase 21.204303979830723 prot_P48570 + 2-oxoglutarat r_0544_EXP_1 homocysteine S-methyltransferase 26.83845029239766 prot_Q12525 + L-homocysteine + S-adenosyl-L-methionine --> H+ + L-methionine + S-adenosyl-L-homocysteine 0.0 r_0544_EXP_2 homocysteine S-methyltransferase 26.80482456140351 prot_Q08985 + L-homocysteine + S-adenosyl-L-methionine --> H+ + L-methionine + S-adenosyl-L-homocysteine 0.0 r_0545 homoisocitrate dehydrogenase 0.6547222222222222 prot_P40495 + homoisocitrate + NAD --> 2-oxoadipic acid + carbon dioxide + NADH 0.09552589561639659 -r_0546 homoserine dehydrogenase (NADH) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADH --> L-homoserine + NAD 0.10278208838588898 +r_0546 homoserine dehydrogenase (NADH) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADH --> L-homoserine + NAD 0.10278208838588837 r_0547 homoserine dehydrogenase (NADP) 0.4736492471213463 prot_P31116 + H+ + L-aspartate 4-semialdehyde + NADPH --> L-homoserine + NADP(+) 0.0 r_0548 homoserine kinase 0.263562091503268 prot_P17423 + ATP + L-homoserine --> ADP + H+ + O-phospho-L-homoserine 0.06820017820653629 -r_0549 homoserine O-trans-acetylase 0.9806103801169591 prot_P08465 + acetyl-CoA + L-homoserine --> coenzyme A + O-acetyl-L-homoserine 0.03458191017935269 +r_0549 homoserine O-trans-acetylase 0.9806103801169591 prot_P08465 + acetyl-CoA + L-homoserine --> coenzyme A + O-acetyl-L-homoserine 0.03458191017935208 r_0550_EXP_1 hydrogen peroxide reductase (thioredoxin) 0.16380116959064328 prot_P22803 + 0.3160087719298246 prot_Q04120 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0550_EXP_2 hydrogen peroxide reductase (thioredoxin) 0.1642543859649123 prot_P22217 + 0.3160087719298246 prot_Q04120 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_0551 hydrogen peroxide reductase (thioredoxin) 0.07592592592592592 prot_P25372 + 0.15517676767676766 prot_P34227 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 @@ -700,26 +700,26 @@ r_0554 hydroxyacylglutathione hydrolase 0.009175746226308025 prot_Q12320 + (R)-S r_0555 hydroxybenzoate octaprenyltransferase 0.8535401716463751 prot_P32378 + 4-hydroxybenzoate + hexaprenyl diphosphate --> 3-hexaprenyl-4-hydroxybenzoic acid + diphosphate 0.0 r_0556 hydroxyethylthiazole kinase 12.64725296618268 prot_P41835 + 5-(2-hydroxyethyl)-4-methylthiazole + ATP --> 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ 0.0 r_0557 hydroxymethylbilane synthase 163.0 prot_P28789 + H2O + 4.0 porphobilinogen --> 4.0 ammonium + preuroporphyrinogen 2.899999992678204e-07 -r_0558_EXP_1 hydroxymethylglutaryl CoA reductase 1.5450320512820512 prot_P12684 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.025548045131232523 +r_0558_EXP_1 hydroxymethylglutaryl CoA reductase 1.5450320512820512 prot_P12684 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.025548045131232537 r_0558_EXP_2 hydroxymethylglutaryl CoA reductase 1.544150641025641 prot_P12683 + 3-hydroxy-3-methylglutaryl-CoA + 2.0 H+ + 2.0 NADPH --> (R)-mevalonate + coenzyme A + 2.0 NADP(+) 0.03861955732936691 -r_0560 hydroxymethylglutaryl CoA synthase 3.322101449275362 prot_P54839 + acetoacetyl-CoA + acetyl-CoA + H2O --> 3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ 0.06416760246059944 +r_0560 hydroxymethylglutaryl CoA synthase 3.322101449275362 prot_P54839 + acetoacetyl-CoA + acetyl-CoA + H2O --> 3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ 0.06416760246059945 r_0561_EXP_1 hydroxymethylpyrimidine kinase (ATP) 39.57945736434109 prot_Q08224 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 3.4800001230905864e-07 r_0561_EXP_2 hydroxymethylpyrimidine kinase (ATP) 39.62144702842377 prot_Q08975 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 r_0561_EXP_3 hydroxymethylpyrimidine kinase (ATP) 340.09581877502734 prot_Q06490 + 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP --> 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ 0.0 r_0562 hypoxanthine phosphoribosyltransferase (Hypoxanthine) 0.30556768558951963 prot_Q04178 + hypoxanthine + PRPP --> diphosphate + IMP 0.0 r_0563 Imidazole-glycerol-3-phosphate synthase 2.4584541062801932 prot_P33734 + 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + L-glutamine --> AICAR + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H+ + L-glutamate 0.0242344554134714 r_0564 imidazoleglycerol-phosphate dehydratase 0.004728769841269841 prot_P06633 + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate --> 3-(imidazol-4-yl)-2-oxopropyl dihydrogen phosphate + H2O 0.0242344554134714 -r_0565_EXP_1 IMP dehydrogenase 6.383242999096658 prot_P38697 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.010666141693506624 +r_0565_EXP_1 IMP dehydrogenase 6.383242999096658 prot_P38697 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.010666141693512422 r_0565_EXP_2 IMP dehydrogenase 6.389453477868112 prot_P50095 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0 r_0565_EXP_3 IMP dehydrogenase 6.367886178861789 prot_P50094 + H2O + IMP + NAD --> H+ + NADH + xanthosine-5-phosphate 0.0032533455897070873 -r_0566 indole-3-glycerol-phosphate synthase 1.550264949662187 prot_P00937 + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ --> 1-C-(indol-3-yl)glycerol 3-phosphate + carbon dioxide + H2O 0.013075001647262715 +r_0566 indole-3-glycerol-phosphate synthase 1.550264949662187 prot_P00937 + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ --> 1-C-(indol-3-yl)glycerol 3-phosphate + carbon dioxide + H2O 0.013075001647263247 r_0567_EXP_1 indole-3-pyruvate decarboxylase 0.27589605734767025 prot_P26263 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 r_0567_EXP_2 indole-3-pyruvate decarboxylase 0.11780651340996169 prot_P06169 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 r_0567_EXP_3 indole-3-pyruvate decarboxylase 0.27738351254480287 prot_P16467 + H+ + indole-3-pyruvate --> carbon dioxide + indol-3-ylacetaldehyde 0.0 -r_0568 inorganic diphosphatase 0.03450854700854701 prot_P00817 + diphosphate + H2O --> H+ + 2.0 phosphate 2.8277033370638764 +r_0568 inorganic diphosphatase 0.03450854700854701 prot_P00817 + diphosphate + H2O --> H+ + 2.0 phosphate 3.2275665567254364 r_0569 inorganic diphosphatase 0.03800534188034188 prot_P28239 + diphosphate + H2O --> H+ + 2.0 phosphate 0.264118379913827 r_0570_EXP_1 inosine monophosphate cyclohydrolase 2.10859173126615 prot_P54113 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.0 -r_0570_EXP_2 inosine monophosphate cyclohydrolase 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.05393134393071035 +r_0570_EXP_2 inosine monophosphate cyclohydrolase 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide --> H2O + IMP 0.053931343930706976 r_0570_REV_EXP_1 inosine monophosphate cyclohydrolase (reversible) 2.10859173126615 prot_P54113 + H2O + IMP --> phosphoribosyl-formamido-carboxamide 0.0 r_0570_REV_EXP_2 inosine monophosphate cyclohydrolase (reversible) 2.1079780361757106 prot_P38009 + H2O + IMP --> phosphoribosyl-formamido-carboxamide 0.0 r_0571 inositol-1,3,4,5,6-pentakisphosphate 2-kinase 12.457614290039357 prot_Q06667 + ATP + myo-inositol 1,3,4,5,6-pentakisphosphate --> ADP + H+ + myo-inositol hexakisphosphate 0.0 @@ -790,7 +790,7 @@ r_0655 IPS phospholipase C 0.03745833333333334 prot_P40015 + H2O + inositol-P-ce r_0656 isoamyl acetate-hydrolyzing esterase 6.693496157764181 prot_P41734 + H2O + isoamyl acetate --> acetate + H+ + isoamylol 0.0 r_0657 isobutyl acetate-hydrolyzing esterase 9.93658635305908 prot_P41734 + H2O + isobutyl acetate --> acetate + H+ + isobutanol 0.0 r_0658 isocitrate dehydrogenase (NAD+) 0.5194640522875817 prot_P28241 + 0.5140392156862745 prot_P28834 + isocitrate + NAD --> 2-oxoglutarate + carbon dioxide + NADH 0.0 -r_0659 isocitrate dehydrogenase (NADP) 0.05072113289760349 prot_P41939 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 2.50194742075915 +r_0659 isocitrate dehydrogenase (NADP) 0.05072113289760349 prot_P41939 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 2.2948399936839543 r_0659_REV isocitrate dehydrogenase (NADP) (reversible) 2.6395691609977323 prot_P41939 + 2-oxoglutarate + carbon dioxide + NADPH --> isocitrate + NADP(+) 0.0 r_0661 isocitrate dehydrogenase (NADP+), peroxisomal 0.05213071895424837 prot_P53982 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.0 r_0662 isocitrate lyase 1.3133207070707071 prot_P28240 + isocitrate --> glyoxylate + succinate 0.0 @@ -805,8 +805,8 @@ r_0667_REV isopentenyl-diphosphate D-isomerase (reversible) 1.1202472121456402 p r_0668 itaconate-CoA ligase (ADP-forming) 0.22156557067271354 prot_P53312 + 0.16549508692365836 prot_P53598 + ATP + coenzyme A + itaconate --> ADP + itaconyl-CoA + phosphate 0.0 r_0668_REV itaconate-CoA ligase (ADP-forming) (reversible) 0.5921843434343435 prot_P53312 + 0.44232323232323234 prot_P53598 + ADP + itaconyl-CoA + phosphate --> ATP + coenzyme A + itaconate 0.0 r_0669 ketol-acid reductoisomerase (2-aceto-2-hydroxybutanoate) 0.6734669095324833 prot_P06168 + (S)-2-acetyl-2-hydroxybutanoate + H+ + NADPH --> (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) 0.07699219285051538 -r_0670 kynureninase 1.2721196709441296 prot_Q05979 + H2O + L-kynurenine --> anthranilate + H+ + L-alanine 0.00012945546184975386 -r_0671 kynurenine 3-monooxygenase 7.174192665571977 prot_P38169 + H+ + L-kynurenine + NADPH + oxygen --> 3-hydroxy-L-kynurenine + H2O + NADP(+) 0.0017602999924600823 +r_0670 kynureninase 1.2721196709441296 prot_Q05979 + H2O + L-kynurenine --> anthranilate + H+ + L-alanine 0.00012945546185284297 +r_0671 kynurenine 3-monooxygenase 7.174192665571977 prot_P38169 + H+ + L-kynurenine + NADPH + oxygen --> 3-hydroxy-L-kynurenine + H2O + NADP(+) 0.0017602999924575258 r_0672 L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase 11.932407407407407 prot_P07275 + 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H2O + NAD --> erythro-4-hydroxy-L-glutamic acid + H+ + NADH 0.0 r_0672_REV L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase (reversible) 11.932407407407407 prot_P07275 + erythro-4-hydroxy-L-glutamic acid + H+ + NADH --> 1-pyrroline-3-hydroxy-5-carboxylic acid + 2.0 H2O + NAD 0.0 r_0673 L-4-hydroxyglutamate semialdehyde dehydrogenase 11.932407407407407 prot_P07275 + H2O + L-4-hydroxyglutamic semialdehyde + NAD --> erythro-4-hydroxy-L-glutamic acid + 2.0 H+ + NADH 0.0 @@ -833,7 +833,7 @@ r_0690 L-serine dehydrogenase 0.7363131313131314 prot_Q05016 + L-serine + NADP(+ r_0691 L-sorbitol dehydrogenase (L-sorbose-producing) 0.7983182730923695 prot_P35497 + L-glucitol + NAD --> H+ + L-sorbose + NADH 0.0 r_0692 L-threonine deaminase 0.007720611346848971 prot_P25379 + L-threonine --> 2-oxobutanoate + ammonium 0.0 r_0693 L-threonine deaminase 0.01253948609146629 prot_P00927 + L-threonine --> 2-oxobutanoate + ammonium 0.0 -r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.3527200202735511 prot_P47125 + L-tryptophan + oxygen --> N-formyl-L-kynurenine 0.0018897554543098362 +r_0694 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 0.3527200202735511 prot_P47125 + L-tryptophan + oxygen --> N-formyl-L-kynurenine 0.0018897554543103687 r_0695 L-tyrosine N-formyltransferase 52.20067092135934 prot_P21623 + 10-formyl-THF + L-tyrosine --> H+ + N-formyl-L-tyrosine + THF 0.0 r_0696 lactaldehyde dehydrogenase 0.033859544541667556 prot_Q12068 + (S)-lactaldehyde + H2O + NAD --> (S)-lactate + 2.0 H+ + NADH 0.0 r_0697 lactoylglutathione lyase 0.005679029304029304 prot_P50107 + glutathione + methylglyoxal --> (R)-S-lactoylglutathione 0.0 @@ -858,16 +858,16 @@ r_0708 leukotriene A4 hydrolase 1.0690022111663904 prot_Q10740 + H2O + leukotrie r_0708_REV leukotriene A4 hydrolase (reversible) 4.1321047008547005 prot_Q10740 + leukotriene B4 --> H2O + leukotriene A4 0.0 r_0711 lysyl-tRNA synthetase 0.41307439824945297 prot_P15180 + ATP + L-lysine + tRNA(Lys) --> AMP + diphosphate + Lys-tRNA(Lys) 0.09552589561639659 r_0712 lysyl-tRNA synthetase 0.40194505227327987 prot_P32048 + ATP + L-lysine + tRNA(Lys) --> AMP + diphosphate + Lys-tRNA(Lys) 0.0 -r_0713 malate dehydrogenase 0.05201038748832867 prot_P17505 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 2.50194742075915 +r_0713 malate dehydrogenase 0.05201038748832867 prot_P17505 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 2.295301448094097 r_0713_REV malate dehydrogenase (reversible) 0.05201038748832867 prot_P17505 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.0 r_0714 malate dehydrogenase, cytoplasmic 0.009916009348524686 prot_P22133 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.0 -r_0714_REV malate dehydrogenase, cytoplasmic (reversible) 9.304413377192983e-05 prot_P22133 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.4606883840152527 +r_0714_REV malate dehydrogenase, cytoplasmic (reversible) 9.304413377192983e-05 prot_P22133 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.46068838401615353 r_0715 malate dehydrogenase, peroxisomal 0.009052974973220372 prot_P32419 + (S)-malate + NAD --> H+ + NADH + oxaloacetate 0.0 r_0715_REV malate dehydrogenase, peroxisomal (reversible) 8.494608918128655e-05 prot_P32419 + H+ + NADH + oxaloacetate --> (S)-malate + NAD 0.0 r_0716_EXP_1 malate synthase 0.9084780092592593 prot_P21826 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 -r_0716_EXP_2 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 +r_0716_EXP_2 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0005006833231986363 r_0717 malate synthase 0.9084346064814814 prot_P30952 + acetyl-CoA + glyoxylate + H2O --> (S)-malate + coenzyme A + H+ 0.0 -r_0718 malic enzyme (NAD) 0.15417910447761193 prot_P36013 + (S)-malate + NAD --> carbon dioxide + NADH + pyruvate 0.18973973943902012 +r_0718 malic enzyme (NAD) 0.15417910447761193 prot_P36013 + (S)-malate + NAD --> carbon dioxide + NADH + pyruvate 0.18973973944022343 r_0719 malic enzyme (NADP) 0.15417910447761193 prot_P36013 + (S)-malate + NADP(+) --> carbon dioxide + NADPH + pyruvate 0.0 r_0721 malonyl-CoA-ACP transacylase 0.0018443121693121694 prot_P32463 + 0.0053845238095238095 prot_Q12283 + H+ + malonyl-CoA + ACP1 --> carboxyacetyl-ACP + coenzyme A 0.0 r_0721_REV malonyl-CoA-ACP transacylase (reversible) 0.0018443121693121694 prot_P32463 + 0.0053845238095238095 prot_Q12283 + carboxyacetyl-ACP + coenzyme A --> H+ + malonyl-CoA + ACP1 0.0 @@ -876,19 +876,19 @@ r_0723 mannose-6-phosphate isomerase 0.6692916666666666 prot_P29952 + D-mannose r_0723_REV mannose-6-phosphate isomerase (reversible) 0.09493498817966903 prot_P29952 + D-fructose 6-phosphate --> D-mannose 6-phosphate 0.20359159999999998 r_0724 methenyltetrahydrifikate cyclohydrolase 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.0 r_0724_REV methenyltetrahydrifikate cyclohydrolase (reversible) 3.8407529390069772 prot_P09440 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O 0.0 -r_0725 methenyltetrahydrofolate cyclohydrolase 1.3619742369207077 prot_P07245 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.06832275898571902 +r_0725 methenyltetrahydrofolate cyclohydrolase 1.3619742369207077 prot_P07245 + 5,10-methenyl-THF + H2O --> 10-formyl-THF + H+ 0.06832275898576756 r_0725_REV methenyltetrahydrofolate cyclohydrolase (reversible) 3.0732170326123236 prot_P07245 + 10-formyl-THF + H+ --> 5,10-methenyl-THF + H2O 0.0 -r_0726_EXP_1 methionine adenosyltransferase 1.565037037037037 prot_P19358 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.042742069644990235 +r_0726_EXP_1 methionine adenosyltransferase 1.565037037037037 prot_P19358 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.04274206964491703 r_0726_EXP_2 methionine adenosyltransferase 19.92471888698304 prot_P10659 + ATP + H2O + L-methionine --> diphosphate + phosphate + S-adenosyl-L-methionine 0.0 -r_0727 methionine synthase 24.2238162581693 prot_P05694 + 5-methyltetrahydrofolate + L-homocysteine --> L-methionine + THF 0.06454311029984798 +r_0727 methionine synthase 24.2238162581693 prot_P05694 + 5-methyltetrahydrofolate + L-homocysteine --> L-methionine + THF 0.06454311029984797 r_0728 methionyl-tRNA formyltransferase 95.33547008547009 prot_P32785 + 10-formyl-THF + Met-tRNA(Met) --> fMet-tRNA(fMet) + H+ + THF 0.0 r_0729 methionyl-tRNA synthetase 0.9519777777777778 prot_P00958 + ATP + L-methionine + tRNA(Met) --> AMP + diphosphate + Met-tRNA(Met) 0.02363426527709509 r_0730 methionyl-tRNA synthetase 0.7414888888888889 prot_P22438 + ATP + L-methionine + tRNA(Met) --> AMP + diphosphate + Met-tRNA(Met) 0.0 -r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 3.4304661673761956 prot_Q02046 + 5,10-methylenetetrahydrofolate + NAD --> 5,10-methenyl-THF + NADH 0.06832275898571902 +r_0731 methylenetetrahydrofolate dehydrogenase (NAD) 3.4304661673761956 prot_Q02046 + 5,10-methylenetetrahydrofolate + NAD --> 5,10-methenyl-THF + NADH 0.06832275898576758 r_0732 methylenetetrahydrofolate dehydrogenase (NADP) 3.1493641930417993 prot_P07245 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) 0.0 r_0733 methylenetetrahydrofolate dehydrogenase (NADP) 3.7131162727717038 prot_P09440 + 5,10-methenyl-THF + NADPH --> 5,10-methylenetetrahydrofolate + NADP(+) 0.0 -r_0734 methylisocitrate lyase 1.3673400673400673 prot_Q12031 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> pyruvate + succinate 0.0 -r_0735 mevalonate kinase (atp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + ATP --> (R)-5-phosphomevalonic acid + ADP + H+ 0.06416760246059944 +r_0734 methylisocitrate lyase 1.3673400673400673 prot_Q12031 + (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid --> pyruvate + succinate 0.00046145441014266997 +r_0735 mevalonate kinase (atp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + ATP --> (R)-5-phosphomevalonic acid + ADP + H+ 0.06416760246059945 r_0736 mevalonate kinase (ctp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + CTP --> (R)-5-phosphomevalonic acid + CDP + H+ 0.0 r_0737 mevalonate kinase (gtp) 0.4723196881091618 prot_P07277 + (R)-mevalonate + GTP --> (R)-5-phosphomevalonic acid + GDP + H+ 0.0 r_0738 mevalonate kinase (UTP) 0.4723196881091618 prot_P07277 + (R)-mevalonate + UTP --> (R)-5-phosphomevalonic acid + H+ + UDP 0.0 @@ -913,16 +913,16 @@ r_0755_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 pro r_0755_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide D (C24) --> GDP + H+ + mannosylinositol phosphorylceramide D (C24) 0.0 r_0756_EXP_1 MIPC synthase 4.373712173815378 prot_P35206 + 4.271689047539152 prot_P38287 + GDP-alpha-D-mannose + inositol-P-ceramide D (C26) --> GDP + H+ + mannosylinositol phosphorylceramide D (C26) 0.0 r_0756_EXP_2 MIPC synthase 16.3020077526028 prot_P33300 + 16.532669083506885 prot_P35206 + GDP-alpha-D-mannose + inositol-P-ceramide D (C26) --> GDP + H+ + mannosylinositol phosphorylceramide D (C26) 0.0 -r_0757_EXP_1 myo-inositol 1-phosphatase 0.03326388888888889 prot_Q05533 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0023940148619654186 +r_0757_EXP_1 myo-inositol 1-phosphatase 0.03326388888888889 prot_Q05533 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0023940148619654065 r_0757_EXP_2 myo-inositol 1-phosphatase 0.0340205223880597 prot_P38710 + 1D-myo-inositol 1-phosphate + H2O --> myo-inositol + phosphate 0.0 -r_0758 myo-inositol-1-phosphate synthase 1.7257523148148148 prot_P11986 + D-glucose 6-phosphate --> 1D-myo-inositol 1-phosphate 0.0023940148619654186 +r_0758 myo-inositol-1-phosphate synthase 1.7257523148148148 prot_P11986 + D-glucose 6-phosphate --> 1D-myo-inositol 1-phosphate 0.0023940148619654065 r_0759 N-acetyl-g-glutamyl-phosphate reductase 3.4224025974025976 prot_Q01217 + H+ + N-acetyl-L-gamma-glutamyl phosphate + NADPH --> 2-acetamido-5-oxopentanoate + NADP(+) + phosphate 0.0903871864052579 r_0760 N-acetylglucosamine-6-phosphate synthase 0.4886032977691562 prot_P43577 + acetyl-CoA + alpha-D-glucosamine 6-phosphate --> coenzyme A + H+ + N-acetyl-D-glucosamine 6-phosphate 0.0068468999999999995 r_0761_EXP_1 N-acteylglutamate synthase 82.8409090909091 prot_P40360 + acetyl-CoA + L-glutamate --> coenzyme A + H+ + N-acetyl-L-glutamate 0.0 r_0761_EXP_2 N-acteylglutamate synthase 0.6359516214779373 prot_Q04728 + acetyl-CoA + L-glutamate --> coenzyme A + H+ + N-acetyl-L-glutamate 0.0 r_0761_REV_EXP_1 N-acteylglutamate synthase (reversible) 23.365384615384617 prot_P40360 + coenzyme A + H+ + N-acetyl-L-glutamate --> acetyl-CoA + L-glutamate 0.0 r_0761_REV_EXP_2 N-acteylglutamate synthase (reversible) 0.6359516214779373 prot_Q04728 + coenzyme A + H+ + N-acetyl-L-glutamate --> acetyl-CoA + L-glutamate 0.0 -r_0762 N-formyl-L-kynurenine amidohydrolase 0.05174430641821946 prot_Q04066 + H2O + N-formyl-L-kynurenine --> formate + H+ + L-kynurenine 0.0018897554543098362 +r_0762 N-formyl-L-kynurenine amidohydrolase 0.05174430641821946 prot_Q04066 + H2O + N-formyl-L-kynurenine --> formate + H+ + L-kynurenine 0.0018897554543103687 r_0763 N-formyltyrosine oxidase 70.69806925295306 prot_P21595 + 77.40588128458634 prot_P21623 + H+ + 2.0 N-formyl-L-tyrosine + NADPH --> N,N'-diformyldityrosine + NADP(+) 0.0 r_0764 NAD diphosphatase 4835.111111111111 prot_P53164 + H2O + NAD --> AMP + 2.0 H+ + NMN 0.0 r_0765_EXP_1 NAD kinase 18.47685185185185 prot_P32622 + ATP + NAD --> ADP + H+ + NADP(+) 0.0 @@ -935,17 +935,17 @@ r_0767_EXP_2 NAD nucleosidase nuclear 42.186868686868685 prot_P53688 + H2O + NAD r_0767_EXP_3 NAD nucleosidase nuclear 58.28484848484848 prot_P53685 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 r_0767_EXP_4 NAD nucleosidase nuclear 51.03434343434343 prot_P53687 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 r_0767_EXP_5 NAD nucleosidase nuclear 40.38282828282828 prot_P53686 + H2O + NAD --> ADP-ribose + H+ + nicotinamide 0.0 -r_0768 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0017606479924723913 +r_0768 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0017606479924698348 r_0769 NAD synthase 3.5019965277777776 prot_P38795 + ATP + deamido-NAD(+) + H2O + L-glutamine --> AMP + diphosphate + H+ + L-glutamate + NAD 0.0 r_0769_REV NAD synthase (reversible) 3.5019965277777776 prot_P38795 + AMP + diphosphate + H+ + L-glutamate + NAD --> ATP + deamido-NAD(+) + H2O + L-glutamine 0.0 -r_0770_EXP_1 NADH dehydrogenase, cytosolic/mitochondrial 0.034255 prot_Q07500 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 6.55548680389638 +r_0770_EXP_1 NADH dehydrogenase, cytosolic/mitochondrial 0.034255 prot_Q07500 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 6.198113580290755 r_0770_EXP_2 NADH dehydrogenase, cytosolic/mitochondrial 0.034874444444444444 prot_P40215 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 0.0 r_0771_EXP_1 NADH kinase 0.9640096618357487 prot_P32622 + ATP + NADH --> ADP + H+ + NADPH 0.0 -r_0771_EXP_2 NADH kinase 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0009483000129719699 +r_0771_EXP_2 NADH kinase 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0009483000129697494 r_0772_EXP_1 NADH kinase mitochondrial 0.9640096618357487 prot_P32622 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0772_EXP_2 NADH kinase mitochondrial 0.04140142021720969 prot_P21373 + ATP + NADH --> ADP + H+ + NADPH 0.0 r_0772_EXP_3 NADH kinase mitochondrial 0.7979123533471358 prot_Q06892 + ATP + NADH --> ADP + H+ + NADPH 0.0 -r_0773 NADH:ubiquinone oxidoreductase 0.03180555555555555 prot_P32340 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 7.318333787147845 +r_0773 NADH:ubiquinone oxidoreductase 0.03180555555555555 prot_P32340 + H+ + NADH + ubiquinone-6 --> NAD + ubiquinol-6 6.69643260727474 r_0774 NAPRtase 62.59351652704193 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 3.4800001230905864e-07 r_0775 NAPRtase 54.465555555555554 prot_P39683 + ATP + H2O + nicotinate + PRPP --> ADP + diphosphate + nicotinic acid D-ribonucleotide + phosphate 0.0 r_0781 nicotinamidase 1.8269736842105264 prot_P53184 + H2O + nicotinamide --> ammonium + nicotinate 3.4800001230905864e-07 @@ -954,9 +954,9 @@ r_0783_EXP_1 nicotinamide-nucleotide adenylyltransferase 0.15292207792207793 pro r_0783_EXP_2 nicotinamide-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + NMN --> diphosphate + NAD 0.0 r_0784_EXP_1 nicotinamide-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + NMN --> diphosphate + NAD 0.0 r_0784_EXP_2 nicotinamide-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + NMN --> diphosphate + NAD 0.0 -r_0785_EXP_1 nicotinate-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0017606479924723913 +r_0785_EXP_1 nicotinate-nucleotide adenylyltransferase 0.23144197072768502 prot_P53204 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0017606479924698348 r_0785_EXP_2 nicotinate-nucleotide adenylyltransferase 0.23633786848072563 prot_Q06178 + ATP + H+ + nicotinic acid D-ribonucleotide --> deamido-NAD(+) + diphosphate 0.0 -r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0017602999924600823 +r_0786 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0017602999924575258 r_0787 nicotinate-nucleotide diphosphorylase (carboxylating) 1.4983796296296297 prot_P43619 + 2.0 H+ + PRPP + quinolinate --> carbon dioxide + diphosphate + nicotinic acid D-ribonucleotide 0.0 r_0788 nucleoside diphosphatase 0.25820037372430643 prot_P40009 + ADP + H2O --> AMP + H+ + phosphate 0.0 r_0789 nucleoside diphosphatase 0.19246758812814743 prot_P40009 + GDP + H2O --> GMP + H+ + phosphate 0.0 @@ -964,12 +964,12 @@ r_0790 nucleoside diphosphatase 0.24671061667353386 prot_P40009 + H2O + UDP --> r_0791 nucleoside diphosphatase 0.004121119814331302 prot_P32621 + H2O + UDP --> H+ + phosphate + UMP 0.0 r_0792 nucleoside diphosphatase 0.00661109270913842 prot_P40009 + CDP + H2O --> CMP + H+ + phosphate 0.0 r_0793 nucleoside diphosphatase 0.24979835905993603 prot_P40009 + H2O + IDP --> H+ + IMP + phosphate 0.0 -r_0795 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + CDP --> ADP + CTP 0.013578034357715516 +r_0795 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + CDP --> ADP + CTP 0.013578034357714895 r_0796 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dADP --> ADP + dATP 0.0 r_0797 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dCDP --> ADP + dCTP 0.0 r_0798 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dGDP --> ADP + dGTP 0.0 r_0799 nucleoside diphosphate kinase 0.3585421888053467 prot_P36010 + ATP + dTDP --> ADP + dTTP 0.0 -r_0800 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + GDP --> ADP + GTP 0.24391184263985383 +r_0800 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + GDP --> ADP + GTP 0.24391184263985044 r_0801 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + IDP --> ADP + ITP 0.0 r_0802 nucleoside diphosphate kinase 0.014855486327448944 prot_P36010 + ATP + dIDP --> ADP + dITP 0.0 r_0802_REV nucleoside diphosphate kinase (reversible) 0.3585421888053467 prot_P36010 + ADP + dITP --> ATP + dIDP 0.0 @@ -984,7 +984,7 @@ r_0807 nucleoside triphosphatase 0.00673132000048749 prot_P47119 + H2O + ITP --> r_0810 nucleoside-diphosphatase (GDP), Golgi 0.004121119814331302 prot_P32621 + GDP + H2O --> GMP + H+ + phosphate 0.0 r_0811 nucleoside-diphosphate kinase (ATP:UDP) 0.014855486327448944 prot_P36010 + ATP + UDP --> ADP + UTP 0.45020360937862586 r_0812 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + methanethiol + O-acetyl-L-homoserine --> acetate + H+ + L-methionine 0.0 -r_0813 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + hydrogen sulfide + O-acetyl-L-homoserine --> acetate + L-homocysteine 0.03458191017935269 +r_0813 O-acetylhomoserine (thiol)-lyase 0.13988618727366786 prot_P06106 + hydrogen sulfide + O-acetyl-L-homoserine --> acetate + L-homocysteine 0.03458191017935208 r_0815_EXP_1 O-succinylhomoserine lyase (L-cysteine) 84.53345338034984 prot_Q12198 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 r_0815_EXP_2 O-succinylhomoserine lyase (L-cysteine) 0.170599173553719 prot_Q04533 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 r_0815_EXP_3 O-succinylhomoserine lyase (L-cysteine) 78.78148148148148 prot_P31373 + L-cysteine + O-succinyl-L-homoserine --> H+ + L-cystathionine + succinate 0.0 @@ -994,49 +994,49 @@ r_0818 ornithine transacetylase 0.6359516214779373 prot_Q04728 + L-glutamate + N r_0819 ornithine transaminase 0.3585901027077497 prot_P07991 + 2-oxoglutarate + ornithine --> L-glutamate + L-glutamic 5-semialdehyde 0.03404128689814415 r_0820_EXP_1 orotate phosphoribosyltransferase 5.27008547008547 prot_P13298 + diphosphate + orotidine 5'-(dihydrogen phosphate) --> orotate + PRPP 0.0 r_0820_EXP_2 orotate phosphoribosyltransferase 5.301495726495727 prot_P30402 + diphosphate + orotidine 5'-(dihydrogen phosphate) --> orotate + PRPP 0.0 -r_0820_REV_EXP_1 orotate phosphoribosyltransferase (reversible) 0.0019386279318367604 prot_P13298 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.031107817482281964 +r_0820_REV_EXP_1 orotate phosphoribosyltransferase (reversible) 0.0019386279318367604 prot_P13298 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.031107817482281988 r_0820_REV_EXP_2 orotate phosphoribosyltransferase (reversible) 0.001950182355530403 prot_P30402 + orotate + PRPP --> diphosphate + orotidine 5'-(dihydrogen phosphate) 0.0 -r_0821 orotidine-5'-phosphate decarboxylase 0.014249512670565302 prot_P03962 + H+ + orotidine 5'-(dihydrogen phosphate) --> carbon dioxide + UMP 0.031107817482281964 -r_0831_EXP_1 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.04684031538764905 prot_P09624 + 0.043736418169126635 prot_P19262 + 0.011871821465312496 prot_P19955 + 0.09922757869641279 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 2.1049464515110623 +r_0821 orotidine-5'-phosphate decarboxylase 0.014249512670565302 prot_P03962 + H+ + orotidine 5'-(dihydrogen phosphate) --> carbon dioxide + UMP 0.031107817482281988 +r_0831_EXP_1 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.04684031538764905 prot_P09624 + 0.043736418169126635 prot_P19262 + 0.011871821465312496 prot_P19955 + 0.09922757869641279 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 1.8967986713782037 r_0831_EXP_2 oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + coenzyme A + S(8)-succinyldihydrolipoamide --> dihydrolipoamide + succinyl-CoA 0.0 -r_0832_EXP_1 oxoglutarate dehydrogenase (lipoamide) 0.023116760828625234 prot_P09624 + 0.021584916966272898 prot_P19262 + 0.005859013867488444 prot_P19955 + 0.048971066598185245 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 2.1049464515110623 +r_0832_EXP_1 oxoglutarate dehydrogenase (lipoamide) 0.023116760828625234 prot_P09624 + 0.021584916966272898 prot_P19262 + 0.005859013867488444 prot_P19955 + 0.048971066598185245 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 1.8967986713782037 r_0832_EXP_2 oxoglutarate dehydrogenase (lipoamide) 0.5396682653876899 prot_P09624 + 0.5039068745003997 prot_P19262 + 1.1432454036770583 prot_P20967 + 2-oxoglutarate + H+ + lipoamide --> carbon dioxide + S(8)-succinyldihydrolipoamide 0.0 -r_0841 pantetheine-phosphate adenylyltransferase 1.9636765345605238 prot_P53332 + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 5.510000177322283e-05 -r_0842 pantothenate kinase 5.359407756813417 prot_Q04430 + (R)-pantothenate + ATP --> (R)-4'-phosphopantothenic acid + ADP + H+ 5.510000177322283e-05 -r_0843 pantothenate synthase 0.07626262626262627 prot_P40459 + (R)-pantoate + ATP + beta-alanine --> (R)-pantothenate + AMP + diphosphate + H+ 5.510000177322283e-05 +r_0841 pantetheine-phosphate adenylyltransferase 1.9636765345605238 prot_P53332 + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 0.0 +r_0842 pantothenate kinase 5.359407756813417 prot_Q04430 + (R)-pantothenate + ATP --> (R)-4'-phosphopantothenic acid + ADP + H+ 5.5100001772612206e-05 +r_0843 pantothenate synthase 0.07626262626262627 prot_P40459 + (R)-pantoate + ATP + beta-alanine --> (R)-pantothenate + AMP + diphosphate + H+ 5.5100001772612206e-05 r_0844 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + decanoyl-CoA + H2O --> coenzyme A + decanoate + H+ 0.0 r_0845 peroxisomal acyl-CoA thioesterase 1.1039815728858178 prot_P41903 + H2O + lauroyl-CoA --> coenzyme A + H+ + laurate 0.0 r_0847 peroxisomal acyl-CoA thioesterase 302.2522522522523 prot_P41903 + H2O + palmitoyl-CoA --> coenzyme A + H+ + palmitate 0.0 -r_0848 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + myristoyl-CoA --> coenzyme A + H+ + myristate 0.0 +r_0848 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + myristoyl-CoA --> coenzyme A + H+ + myristate 3.922891305596643e-05 r_0849 peroxisomal acyl-CoA thioesterase 588.5964912280702 prot_P41903 + H2O + stearoyl-CoA --> coenzyme A + H+ + stearate 0.0 r_0850 peroxisomal acyl-CoA thioesterase 0.12566955088586731 prot_P41903 + H2O + octanoyl-CoA --> coenzyme A + H+ + octanoate 0.0 r_0851 phenylalanine transaminase 1.8801204819277106 prot_P53090 + 2-oxoglutarate + L-phenylalanine --> keto-phenylpyruvate + L-glutamate 0.0 -r_0851_REV phenylalanine transaminase (reversible) 0.550322030209992 prot_P53090 + keto-phenylpyruvate + L-glutamate --> 2-oxoglutarate + L-phenylalanine 0.18300213692624728 +r_0851_REV phenylalanine transaminase (reversible) 0.550322030209992 prot_P53090 + keto-phenylpyruvate + L-glutamate --> 2-oxoglutarate + L-phenylalanine 0.18300213692624673 r_0852 phenylalanyl-tRNA synthetase 0.06206467661691542 prot_P15624 + 0.05298599594619495 prot_P15625 + ATP + L-phenylalanine + tRNA(Phe) --> AMP + diphosphate + Phe-tRNA(Phe) 0.04837082782774793 r_0853 phenylalanyl-tRNA synthetase 0.025257508752533627 prot_P08425 + ATP + L-phenylalanine + tRNA(Phe) --> AMP + diphosphate + Phe-tRNA(Phe) 0.0 r_0854 phenylpyruvate decarboxylase 0.9914444444444445 prot_Q06408 + H+ + keto-phenylpyruvate --> carbon dioxide + phenylacetaldehyde 0.0 -r_0855 phopshoribosylaminoimidazole synthetase 3.4153968253968254 prot_P07244 + 5'-phosphoribosyl-N-formylglycineamidine + ATP --> 5'-phosphoribosyl-5-aminoimidazole + ADP + H+ + phosphate 0.02969723651725126 +r_0855 phopshoribosylaminoimidazole synthetase 3.4153968253968254 prot_P07244 + 5'-phosphoribosyl-N-formylglycineamidine + ATP --> 5'-phosphoribosyl-5-aminoimidazole + ADP + H+ + phosphate 0.029697236517247882 r_0882 phosphoacetylglucosamine mutase 0.4264366394591475 prot_P38628 + N-acetyl-D-glucosamine 6-phosphate --> N-acetyl-alpha-D-glucosamine 1-phosphate 0.0068468999999999995 r_0882_REV phosphoacetylglucosamine mutase (reversible) 0.4264366394591475 prot_P38628 + N-acetyl-alpha-D-glucosamine 1-phosphate --> N-acetyl-D-glucosamine 6-phosphate 0.0 -r_0883_EXP_1 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8892063492063492 prot_P22803 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.034582258179365 +r_0883_EXP_1 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8892063492063492 prot_P22803 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.03458225817936439 r_0883_EXP_2 phosphoadenylyl-sulfate reductase (thioredoxin) 2.411111111111111 prot_P18408 + 0.8916666666666667 prot_P22217 + 3'-phospho-5'-adenylyl sulfate + TRX1 --> adenosine 3',5'-bismonophosphate + H+ + sulphite + TRX1 disulphide 0.0 r_0884 phosphoenolpyruvate carboxykinase 0.27322132616487455 prot_P10963 + ATP + oxaloacetate --> ADP + carbon dioxide + phosphoenolpyruvate 0.0 r_0885 phosphoethanolamine cytidyltransferase 8.904106280193236 prot_P33412 + CTP + H+ + O-phosphoethanolamine --> CDP-ethanolamine + diphosphate 0.0 -r_0886 phosphofructokinase 0.06875388870533351 prot_P16861 + 0.06661937879572642 prot_P16862 + ATP + D-fructose 6-phosphate --> ADP + D-fructose 1,6-bisphosphate + H+ 5.009728838904098 +r_0886 phosphofructokinase 0.06875388870533351 prot_P16861 + 0.06661937879572642 prot_P16862 + ATP + D-fructose 6-phosphate --> ADP + D-fructose 1,6-bisphosphate + H+ 5.041870968737412 r_0888_EXP_1 phosphoglucomutase 0.08151033591731266 prot_P37012 + D-glucose 6-phosphate --> D-glucose 1-phosphate 0.42906659999999996 r_0888_EXP_2 phosphoglucomutase 0.08154005167958657 prot_P33401 + D-glucose 6-phosphate --> D-glucose 1-phosphate 0.0 r_0888_REV_EXP_1 phosphoglucomutase (reversible) 0.08151033591731266 prot_P37012 + D-glucose 1-phosphate --> D-glucose 6-phosphate 0.0 r_0888_REV_EXP_2 phosphoglucomutase (reversible) 0.08154005167958657 prot_P33401 + D-glucose 1-phosphate --> D-glucose 6-phosphate 0.0 r_0889_EXP_1 phosphogluconate dehydrogenase 0.41150030525030523 prot_P53319 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.0 -r_0889_EXP_2 phosphogluconate dehydrogenase 0.40860042735042734 prot_P38720 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.1712230135015525 +r_0889_EXP_2 phosphogluconate dehydrogenase 0.40860042735042734 prot_P38720 + 6-phospho-D-gluconate + NADP(+) --> carbon dioxide + D-ribulose 5-phosphate + NADPH 0.0747966240017505 r_0890 phosphoglucosamine mutase 0.4264366394591475 prot_P38628 + alpha-D-glucosamine 1-phosphate --> alpha-D-glucosamine 6-phosphate 0.0 r_0890_REV phosphoglucosamine mutase (reversible) 0.4264366394591475 prot_P38628 + alpha-D-glucosamine 6-phosphate --> alpha-D-glucosamine 1-phosphate 0.0 r_0891_EXP_1 phosphoglycerate dehydrogenase 0.0036935786435786434 prot_P40054 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.0 -r_0891_EXP_2 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.25387828577226296 -r_0892 phosphoglycerate kinase 0.02315487650870546 prot_P00560 + 1,3-bisphospho-D-glycerate + ADP --> 3-phosphonato-D-glycerate(3-) + ATP 9.97066672873656 +r_0891_EXP_2 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + 3-phosphonato-D-glycerate(3-) + NAD --> 3-phospho-hydroxypyruvate + H+ + NADH 0.2538782857723108 +r_0892 phosphoglycerate kinase 0.02315487650870546 prot_P00560 + 1,3-bisphospho-D-glycerate + ADP --> 3-phosphonato-D-glycerate(3-) + ATP 10.00280885856995 r_0892_REV phosphoglycerate kinase (reversible) 0.02315487650870546 prot_P00560 + 3-phosphonato-D-glycerate(3-) + ATP --> 1,3-bisphospho-D-glycerate + ADP 0.0 r_0893_EXP_1 phosphoglycerate mutase 1.1738045797601886 prot_Q12040 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 0.0 -r_0893_EXP_2 phosphoglycerate mutase 0.013314525462962964 prot_P00950 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 9.716788442964297 +r_0893_EXP_2 phosphoglycerate mutase 0.013314525462962964 prot_P00950 + 3-phosphonato-D-glycerate(3-) --> 2-phospho-D-glyceric acid 9.748930572797638 r_0893_REV_EXP_1 phosphoglycerate mutase (reversible) 2.640272344101795 prot_Q12040 + 2-phospho-D-glyceric acid --> 3-phosphonato-D-glycerate(3-) 0.0 r_0893_REV_EXP_2 phosphoglycerate mutase (reversible) 0.013314525462962964 prot_P00950 + 2-phospho-D-glyceric acid --> 3-phosphonato-D-glycerate(3-) 0.0 r_0902 phosphomannomutase 1.8347853535353533 prot_P07283 + D-mannose 1-phosphate --> D-mannose 6-phosphate 0.0 @@ -1044,33 +1044,33 @@ r_0902_REV phosphomannomutase (reversible) 0.40001070189485594 prot_P07283 + D-m r_0903_EXP_1 phosphomethylpyrimidine kinase 39.57945736434109 prot_Q08224 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 3.4800001230905864e-07 r_0903_EXP_2 phosphomethylpyrimidine kinase 39.62144702842377 prot_Q08975 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 0.0 r_0903_EXP_3 phosphomethylpyrimidine kinase 695.1822835935426 prot_Q06490 + 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP --> 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP 0.0 -r_0904 phosphomevalonate kinase 4.122140522875817 prot_P24521 + (R)-5-phosphomevalonic acid + ATP --> (R)-5-diphosphomevalonic acid + ADP 0.06416760246059944 -r_0905 phosphopantothenate-cysteine ligase 4.010249042145594 prot_P40506 + (R)-4'-phosphopantothenic acid + CTP + L-cysteine --> CMP + diphosphate + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine 5.510000177322283e-05 -r_0906 phosphopantothenoylcysteine decarboxylase 5.98448275862069 prot_P36024 + 6.248850574712644 prot_P36076 + 7.054501915708812 prot_Q08438 + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine --> carbon dioxide + pantetheine 4'-phosphate 5.510000177322283e-05 +r_0904 phosphomevalonate kinase 4.122140522875817 prot_P24521 + (R)-5-phosphomevalonic acid + ATP --> (R)-5-diphosphomevalonic acid + ADP 0.06416760246059945 +r_0905 phosphopantothenate-cysteine ligase 4.010249042145594 prot_P40506 + (R)-4'-phosphopantothenic acid + CTP + L-cysteine --> CMP + diphosphate + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine 5.5100001772612206e-05 +r_0906 phosphopantothenoylcysteine decarboxylase 5.98448275862069 prot_P36024 + 6.248850574712644 prot_P36076 + 7.054501915708812 prot_Q08438 + H+ + N-[(R)-4-phosphonopantothenoyl]-L-cysteine --> carbon dioxide + pantetheine 4'-phosphate 5.5100001772612206e-05 r_0907_EXP_1 phosphopentomutase 0.08154005167958657 prot_P33401 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_EXP_2 phosphopentomutase 0.08151033591731266 prot_P37012 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_EXP_3 phosphopentomutase 0.10671021021021021 prot_Q03262 + alpha-D-ribose 1-phosphate(2-) --> ribose-5-phosphate 0.0 r_0907_REV_EXP_1 phosphopentomutase (reversible) 0.08154005167958657 prot_P33401 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0 -r_0907_REV_EXP_2 phosphopentomutase (reversible) 0.08151033591731266 prot_P37012 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.001833224622237145 +r_0907_REV_EXP_2 phosphopentomutase (reversible) 0.08151033591731266 prot_P37012 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.001833224622164148 r_0907_REV_EXP_3 phosphopentomutase (reversible) 0.10671021021021021 prot_Q03262 + ribose-5-phosphate --> alpha-D-ribose 1-phosphate(2-) 0.0 -r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.17755272474518155 prot_P27616 + ATP + L-aspartate + phosphoribosyl-carboxy-aminoimidazole --> 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + 2.0 H+ + phosphate 0.02969688851723895 +r_0908 phosphoribosyl amino imidazolesuccinocarbozamide synthetase 0.17755272474518155 prot_P27616 + ATP + L-aspartate + phosphoribosyl-carboxy-aminoimidazole --> 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + 2.0 H+ + phosphate 0.02969688851723557 r_0909 phosphoribosyl-AMP cyclohydrolase 0.00852140040022537 prot_P00815 + 1-(5-phosphoribosyl)-5'-AMP + H2O --> 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide 0.0242344554134714 r_0910 phosphoribosyl-ATP pyrophosphatase 6.601766492974471 prot_P00815 + 5-phosphoribosyl-ATP + H2O --> 1-(5-phosphoribosyl)-5'-AMP + diphosphate + H+ 0.0242344554134714 -r_0911 phosphoribosylaminoimidazole-carboxylase 0.2248881673881674 prot_P21264 + 5'-phosphoribosyl-5-aminoimidazole + carbon dioxide --> H+ + phosphoribosyl-carboxy-aminoimidazole 0.02969688851723895 +r_0911 phosphoribosylaminoimidazole-carboxylase 0.2248881673881674 prot_P21264 + 5'-phosphoribosyl-5-aminoimidazole + carbon dioxide --> H+ + phosphoribosyl-carboxy-aminoimidazole 0.02969688851723557 r_0912_EXP_1 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.10859173126615 prot_P54113 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.0 -r_0912_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.1079780361757106 prot_P38009 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.05393134393071035 +r_0912_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase 2.1079780361757106 prot_P38009 + 10-formyl-THF + AICAR --> phosphoribosyl-formamido-carboxamide + THF 0.053931343930706976 r_0912_REV_EXP_1 phosphoribosylaminoimidazolecarboxamide formyltransferase (reversible) 2.10859173126615 prot_P54113 + phosphoribosyl-formamido-carboxamide + THF --> 10-formyl-THF + AICAR 0.0 r_0912_REV_EXP_2 phosphoribosylaminoimidazolecarboxamide formyltransferase (reversible) 2.1079780361757106 prot_P38009 + phosphoribosyl-formamido-carboxamide + THF --> 10-formyl-THF + AICAR 0.0 -r_0913 phosphoribosylanthranilate isomerase 0.09719806763285024 prot_P00912 + N-(5-phospho-beta-D-ribosyl)anthranilate --> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 0.013075001647262715 -r_0914 phosphoribosylglycinamidine synthetase 3.4153968253968254 prot_P07244 + 5-phosphoribosylamine + ATP + L-glycine --> 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate 0.02969723651725126 -r_0915 phosphoribosylpyrophosphate amidotransferase 0.28336830535571544 prot_P04046 + H2O + L-glutamine + PRPP --> 5-phosphoribosylamine + diphosphate + L-glutamate 0.02969723651725126 -r_0916_EXP_1 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11565202927478377 prot_P38620 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.09987515905273972 +r_0913 phosphoribosylanthranilate isomerase 0.09719806763285024 prot_P00912 + N-(5-phospho-beta-D-ribosyl)anthranilate --> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate 0.013075001647263247 +r_0914 phosphoribosylglycinamidine synthetase 3.4153968253968254 prot_P07244 + 5-phosphoribosylamine + ATP + L-glycine --> 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate 0.029697236517247882 +r_0915 phosphoribosylpyrophosphate amidotransferase 0.28336830535571544 prot_P04046 + H2O + L-glutamine + PRPP --> 5-phosphoribosylamine + diphosphate + L-glutamate 0.029697236517247882 +r_0916_EXP_1 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11565202927478377 prot_P38620 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.09987515905273435 r_0916_EXP_2 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11684630738522954 prot_P38689 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_3 phosphoribosylpyrophosphate synthetase 0.1565103127079175 prot_P32895 + 0.11882900864936793 prot_P38063 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_4 phosphoribosylpyrophosphate synthetase 0.11565202927478377 prot_P38620 + 0.17799401197604792 prot_Q12265 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 r_0916_EXP_5 phosphoribosylpyrophosphate synthetase 0.11882900864936793 prot_P38063 + 0.17799401197604792 prot_Q12265 + ATP + ribose-5-phosphate --> AMP + H+ + PRPP 0.0 -r_0917 phosphoserine phosphatase (L-serine) 0.006309392061384094 prot_P42941 + 3-phospho-serine + H2O --> L-serine + phosphate 0.25387828577226296 -r_0918 phosphoserine transaminase 4.103165485515034 prot_P33330 + 3-phospho-hydroxypyruvate + L-glutamate --> 2-oxoglutarate + 3-phospho-serine 0.25387828577226296 +r_0917 phosphoserine phosphatase (L-serine) 0.006309392061384094 prot_P42941 + 3-phospho-serine + H2O --> L-serine + phosphate 0.2538782857723108 +r_0918 phosphoserine transaminase 4.103165485515034 prot_P33330 + 3-phospho-hydroxypyruvate + L-glutamate --> 2-oxoglutarate + 3-phospho-serine 0.2538782857723108 r_0919 phytoceramidase 13.387690165065315 prot_P38298 + lignoceric acid + phytosphingosine --> ceramide-2 (C24) + H2O 0.0 r_0920 phytoceramidase 107.0999354737445 prot_P21595 + cerotic acid + phytosphingosine --> ceramide-2 (C26) + H2O 0.0 r_0921 Phytosphingosine phosphate lyase 82.78535353535354 prot_Q05567 + phytosphingosine 1-phosphate --> 2-hydroxyhexadecanal + O-phosphoethanolamine 0.0 @@ -1078,7 +1078,7 @@ r_0922 phytosphingosine synthesis 30.50853889148629 prot_P38992 + H+ + NADPH + o r_0929 polyamine oxidase 0.4117236467236467 prot_P50264 + H2O + N(1)-acetylspermidine + oxygen --> 3-aminopropanal + hydrogen peroxide + N-acetylputrescine 0.0 r_0935 porphobilinogen synthase 1.9935529153386848 prot_P05373 + 2.0 5-aminolevulinate --> H+ + 2.0 H2O + porphobilinogen 1.1599999970712816e-06 r_0936 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + N(1)-acetylspermine + oxygen --> 3-aminopropanal + hydrogen peroxide + N(1)-acetylspermidine 0.0 -r_0937 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + oxygen + spermine --> 3-aminopropanal + hydrogen peroxide + spermidine 0.0018332246222373496 +r_0937 poylamine oxidase 0.4117236467236467 prot_P50264 + H2O + oxygen + spermine --> 3-aminopropanal + hydrogen peroxide + spermidine 0.001833224622164148 r_0938 prephenate dehydratase 0.012934651669576752 prot_P32452 + H+ + prephenate --> carbon dioxide + H2O + keto-phenylpyruvate 0.04837082782774793 r_0939 prephenate dehydrogenase (NADP) 0.537843261512463 prot_P20049 + NAD + prephenate --> 3-(4-hydroxyphenyl)pyruvate + carbon dioxide + NADH 0.03567744162992795 r_0940 proline oxidase (NAD) 0.44171641791044775 prot_P09368 + FAD + L-proline --> 1-pyrroline-5-carboxylate + FADH2 0.0 @@ -1096,23 +1096,23 @@ r_0954 pyridoxamine 5'-phosphate oxidase 72.56742179072278 prot_P38075 + H2O + o r_0955 pyridoxine 5'-phosphate oxidase 10.677777777777777 prot_P38075 + oxygen + pyridoxine 5'-phosphate --> hydrogen peroxide + pyridoxal 5'-phosphate 0.0 r_0956 pyridoxine oxidase 10.677777777777777 prot_P38075 + oxygen + pyridoxine --> hydrogen peroxide + pyridoxal 0.0 r_0957 pyrroline-5-carboxylate reductase 0.0020925 prot_P32263 + 1-pyrroline-5-carboxylate + 2.0 H+ + NADPH --> L-proline + NADP(+) 0.05214813332646313 -r_0958_EXP_1 pyruvate carboxylase 0.602625 prot_P32327 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.46588217577209584 +r_0958_EXP_1 pyruvate carboxylase 0.602625 prot_P32327 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.2315866603158767 r_0958_EXP_2 pyruvate carboxylase 0.6023101851851852 prot_P11154 + ATP + bicarbonate + pyruvate --> ADP + H+ + oxaloacetate + phosphate 0.9610509271458045 r_0959_EXP_1 pyruvate decarboxylase 0.27589605734767025 prot_P26263 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.0 -r_0959_EXP_2 pyruvate decarboxylase 0.08176022088979121 prot_P06169 + H+ + pyruvate --> acetaldehyde + carbon dioxide 7.219094518634218 +r_0959_EXP_2 pyruvate decarboxylase 0.08176022088979121 prot_P06169 + H+ + pyruvate --> acetaldehyde + carbon dioxide 5.995992810919838 r_0959_EXP_3 pyruvate decarboxylase 0.27738351254480287 prot_P16467 + H+ + pyruvate --> acetaldehyde + carbon dioxide 0.0 r_0960_EXP_1 pyruvate decarboxylase (acetoin-forming) 0.27589605734767025 prot_P26263 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 r_0960_EXP_2 pyruvate decarboxylase (acetoin-forming) 0.11780651340996169 prot_P06169 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 r_0960_EXP_3 pyruvate decarboxylase (acetoin-forming) 0.27738351254480287 prot_P16467 + acetaldehyde + H+ + pyruvate --> (R)-acetoin + carbon dioxide 0.0 -r_0961 pyruvate dehydrogenase 0.23664570803230708 prot_P09624 + 1.1352071189426114 prot_P12695 + 0.4061052415234663 prot_P16387 + 0.19875435304131667 prot_P16451 + 0.35099452655160257 prot_P32473 + coenzyme A + NAD + pyruvate --> acetyl-CoA + carbon dioxide + NADH 0.5007023682570142 -r_0962_EXP_1 pyruvate kinase 0.06530771072796934 prot_P00549 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 9.522764039676645 +r_0961 pyruvate dehydrogenase 0.23664570803230708 prot_P09624 + 1.1352071189426114 prot_P12695 + 0.4061052415234663 prot_P16387 + 0.19875435304131667 prot_P16451 + 0.35099452655160257 prot_P32473 + coenzyme A + NAD + pyruvate --> acetyl-CoA + carbon dioxide + NADH 2.000650487484786 +r_0962_EXP_1 pyruvate kinase 0.06530771072796934 prot_P00549 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 9.554906169509989 r_0962_EXP_2 pyruvate kinase 0.06608596743295019 prot_P52489 + ADP + H+ + phosphoenolpyruvate --> ATP + pyruvate 0.0 r_0963 quinone oxidoreductase 0.2834173315594083 prot_O13525 + 0.266570923780901 prot_P27680 + 0.191209663200305 prot_P41735 + 0.2544937516539746 prot_P49017 + 0.39274288726487816 prot_P53318 + 0.21981040253855474 prot_Q05779 + 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + NADH + oxygen --> 2-hexaprenyl-5-hydroxy-6-methoxy-3-methyl-1,4-benzoquinone + H2O + NAD 0.0 r_0964 reduced glutathione via ABC system 161.4141633681904 prot_P39109 + ATP + glutathione + H2O --> ADP + glutathione + H+ + phosphate 0.0 r_0965 riboflavin kinase 68.15833333333333 prot_Q03778 + ATP + riboflavin --> ADP + FMN + H+ 0.0 -r_0966 riboflavin kinase 68.15833333333333 prot_Q03778 + ATP + riboflavin --> ADP + FMN + H+ 0.0 -r_0967 riboflavin synthase 1.4057441999969114 prot_P50861 + 2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil --> 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ + 2.0 H2O + phosphate 0.0005799999832379401 -r_0968 riboflavin synthase 54.506866416978774 prot_P38145 + 2.0 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ --> 5-amino-6-(D-ribitylamino)uracil + riboflavin 0.00028999999161897003 +r_0966 riboflavin kinase 68.15833333333333 prot_Q03778 + ATP + riboflavin --> ADP + FMN + H+ 2.8999999267398372e-06 +r_0967 riboflavin synthase 1.4057441999969114 prot_P50861 + 2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil --> 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ + 2.0 H2O + phosphate 0.0005799999832495165 +r_0968 riboflavin synthase 54.506866416978774 prot_P38145 + 2.0 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ --> 5-amino-6-(D-ribitylamino)uracil + riboflavin 0.00028999999162475826 r_0969 ribokinase 0.214529735759604 prot_P25332 + ATP + D-ribose --> ADP + H+ + ribose-5-phosphate 0.0 r_0970 ribonucleoside-triphosphate reductase (ATP) 1.6386358549460274 prot_P22803 + ATP + H+ + TRX1 --> dATP + H2O + TRX1 disulphide 0.0 r_0971 ribonucleoside-triphosphate reductase (CTP) 3.573997388312029 prot_P22803 + CTP + H+ + TRX1 --> dCTP + H2O + TRX1 disulphide 0.0 @@ -1142,11 +1142,11 @@ r_0979_EXP_1 ribonucleotide reductase 2.143863049095607 prot_P21524 + GDP + H+ + r_0979_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 r_0979_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 r_0979_EXP_4 ribonucleotide reductase 0.9936907838070629 prot_P09938 + GDP + H+ + TRX1 --> dGDP + H2O + TRX1 disulphide 0.0 -r_0982 ribose-5-phosphate isomerase 0.5468480156600358 prot_Q12189 + D-ribulose 5-phosphate --> ribose-5-phosphate 0.15702399417069846 +r_0982 ribose-5-phosphate isomerase 0.5468480156600358 prot_Q12189 + D-ribulose 5-phosphate --> ribose-5-phosphate 0.12488186433737417 r_0982_REV ribose-5-phosphate isomerase (reversible) 0.817650462962963 prot_Q12189 + ribose-5-phosphate --> D-ribulose 5-phosphate 0.0 r_0983 ribosylnicotinamide kinase 4.5245098039215685 prot_P53915 + ATP + nicotinamide riboside --> ADP + H+ + NMN 0.0 -r_0984 ribulose 5-phosphate 3-epimerase 0.06355115026921195 prot_P46969 + D-ribulose 5-phosphate --> D-xylulose 5-phosphate 0.013619019347616113 -r_0984_REV ribulose 5-phosphate 3-epimerase (reversible) 0.06355115026921195 prot_P46969 + D-xylulose 5-phosphate --> D-ribulose 5-phosphate 0.0 +r_0984 ribulose 5-phosphate 3-epimerase 0.06355115026921195 prot_P46969 + D-ribulose 5-phosphate --> D-xylulose 5-phosphate 0.0 +r_0984_REV ribulose 5-phosphate 3-epimerase (reversible) 0.06355115026921195 prot_P46969 + D-xylulose 5-phosphate --> D-ribulose 5-phosphate 0.05066524031887318 r_0985 S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase 0.55303275478674 prot_O13525 + 0.5201603286342985 prot_P27680 + 0.37310776373372107 prot_P41735 + 0.49659412068703435 prot_P49017 + 0.7663599105669565 prot_P53318 + 0.42891643844723004 prot_Q05779 + 3-hexaprenyl-4,5-dihydroxybenzoic acid + S-adenosyl-L-methionine --> 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid + H+ + S-adenosyl-L-homocysteine 0.0 r_0986 S-adenosyl-methionine delta-24-sterol-c-methyltransferase 1096.7424242424245 prot_P25087 + S-adenosyl-L-methionine + zymosterol --> fecosterol + H+ + S-adenosyl-L-homocysteine 0.0 r_0987 S-formylglutathione hydralase 0.3307407407407407 prot_P40363 + H2O + S-formylglutathione --> formate + glutathione + H+ 0.0 @@ -1158,14 +1158,14 @@ r_0992 serine O-acetyltransferase 17.435821109618253 prot_P07347 + 62.4747269081 r_0993 serine palmitotransferase 11.220598845598845 prot_P25045 + 12.829184704184705 prot_P32368 + 11.383658008658008 prot_P40970 + 4.553571428571429 prot_P53224 + 4.483225108225108 prot_Q06144 + 1.727813852813853 prot_Q3E790 + H+ + L-serine + palmitoyl-CoA --> 3-ketosphinganine + carbon dioxide + coenzyme A 0.0 r_0995_EXP_1 seryl-tRNA synthetase 3.797008547008547 prot_P07284 + ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + Ser-tRNA(Ser) 0.07944666996534745 r_0995_EXP_2 seryl-tRNA synthetase 3.589031339031339 prot_P38705 + ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + Ser-tRNA(Ser) 0.0010937711397376346 -r_0996 shikimate dehydrogenase 0.12478934590117109 prot_P08566 + 3-dehydroshikimate + H+ + NADPH --> NADP(+) + shikimate 0.09701220164382707 -r_0997 shikimate kinase 0.1645527306967985 prot_P08566 + ATP + shikimate --> 3-phosphoshikimic acid + ADP + H+ 0.09701220164382707 +r_0996 shikimate dehydrogenase 0.12478934590117109 prot_P08566 + 3-dehydroshikimate + H+ + NADPH --> NADP(+) + shikimate 0.09701220164382451 +r_0997 shikimate kinase 0.1645527306967985 prot_P08566 + ATP + shikimate --> 3-phosphoshikimic acid + ADP + H+ 0.09701220164382451 r_0998 sirohydrochlorin dehydrogenase 147.7685185185185 prot_P15807 + NAD + precorrin-2 --> 2.0 H+ + NADH + sirohydrochlorin 0.0 r_0999 sirohydrochlorin ferrochetalase 147.7685185185185 prot_P15807 + iron(2+) + sirohydrochlorin --> 2.0 H+ + siroheme 0.0 r_1000 fumarate reductase (FMN) 0.9170995670995671 prot_P32614 + FMNH2 + fumarate --> FMN + H+ + succinate 0.0 r_1000_REV fumarate reductase (FMN) (reversible) 0.9170995670995671 prot_P32614 + FMN + H+ + succinate --> FMNH2 + fumarate 0.0 r_1001 spermidine synthase 0.4077826725403818 prot_Q12074 + putrescine + S-adenosylmethioninamine --> 5'-S-methyl-5'-thioadenosine + H+ + spermidine 0.0 -r_1002 spermine synthase 0.29592881944444444 prot_Q12455 + S-adenosylmethioninamine + spermidine --> 5'-S-methyl-5'-thioadenosine + H+ + spermine 0.0018332246222373496 +r_1002 spermine synthase 0.29592881944444444 prot_Q12455 + S-adenosylmethioninamine + spermidine --> 5'-S-methyl-5'-thioadenosine + H+ + spermine 0.001833224622164148 r_1003 sphinganine phosphate lyase 1214.1851851851852 prot_Q05567 + sphinganine 1-phosphate --> hexadecanal + O-phosphoethanolamine 0.0 r_1004_EXP_1 sphingoid base-phosphate phosphatase (phytosphingosine 1-phosphate) 1940.4587619197007 prot_P47013 + H2O + phytosphingosine 1-phosphate --> phosphate + phytosphingosine 0.0 r_1004_EXP_2 sphingoid base-phosphate phosphatase (phytosphingosine 1-phosphate) 8490.20229957777 prot_P23501 + H2O + phytosphingosine 1-phosphate --> phosphate + phytosphingosine 0.0 @@ -1184,16 +1184,16 @@ r_1011 squalene epoxidase (NADP) 161.16753104520652 prot_P32476 + H+ + NADPH + o r_1012 squalene synthase 8.707070707070708 prot_P29704 + 2.0 farnesyl diphosphate + H+ + NADPH --> 2.0 diphosphate + NADP(+) + squalene 0.010694455410100273 r_1021_EXP_1 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07412606837606837 prot_P47052 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.0 r_1021_EXP_2 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.02163354700854701 prot_P37298 + 0.07503098290598291 prot_Q00711 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 0.0 -r_1021_EXP_3 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.07412606837606837 prot_P47052 + 0.019905982905982906 prot_Q06236 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 2.13605194899335 +r_1021_EXP_3 succinate dehydrogenase (ubiquinone-6) 0.03229807692307692 prot_P21801 + 0.02357692307692308 prot_P33421 + 0.07412606837606837 prot_P47052 + 0.019905982905982906 prot_Q06236 + succinate + ubiquinone-6 --> fumarate + ubiquinol-6 1.9289081930053404 r_1021_REV_EXP_1 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.022498888888888888 prot_P37298 + 0.07709111111111111 prot_P47052 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 r_1021_REV_EXP_2 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.022498888888888888 prot_P37298 + 0.07803222222222223 prot_Q00711 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 r_1021_REV_EXP_3 succinate dehydrogenase (ubiquinone-6) (reversible) 0.03359 prot_P21801 + 0.02452 prot_P33421 + 0.07709111111111111 prot_P47052 + 0.020702222222222223 prot_Q06236 + fumarate + ubiquinol-6 --> succinate + ubiquinone-6 0.0 -r_1022 succinate-CoA ligase (ADP-forming) 0.06481619679380873 prot_P53312 + 0.048413488114980655 prot_P53598 + ADP + phosphate + succinyl-CoA --> ATP + coenzyme A + succinate 0.0 -r_1023 succinate-semialdehyde dehydrogenase (NADP) 0.6660398230088496 prot_P38067 + H2O + NADP(+) + succinic semialdehyde --> 2.0 H+ + NADPH + succinate 0.0 +r_1022 succinate-CoA ligase (ADP-forming) 0.06481619679380873 prot_P53312 + 0.048413488114980655 prot_P53598 + ADP + phosphate + succinyl-CoA --> ATP + coenzyme A + succinate 1.498907766170125 +r_1023 succinate-semialdehyde dehydrogenase (NADP) 0.6660398230088496 prot_P38067 + H2O + NADP(+) + succinic semialdehyde --> 2.0 H+ + NADPH + succinate 0.0005396697347794297 r_1024 sucrose hydrolyzing enzyme 0.004910835762876579 prot_P00724 + H2O + sucrose --> D-fructose + D-glucose 0.0 -r_1025 sulfate adenylyltransferase 0.6571607468123861 prot_P08536 + ATP + H+ + sulphate --> 5'-adenylyl sulfate + diphosphate 0.034582258179365 +r_1025 sulfate adenylyltransferase 0.6571607468123861 prot_P08536 + ATP + H+ + sulphate --> 5'-adenylyl sulfate + diphosphate 0.03458225817936439 r_1026 sulfate adenylyltransferase (ADP) 0.10559317129629629 prot_P16550 + 5'-adenylyl sulfate + phosphate --> ADP + H+ + sulphate 0.0 -r_1027 sulfite reductase (NADPH2) 0.4089351851851852 prot_P39692 + 0.574141737891738 prot_P47169 + 4.0 H+ + 3.0 NADPH + sulphite --> 3.0 H2O + hydrogen sulfide + 3.0 NADP(+) 0.034582258179365 +r_1027 sulfite reductase (NADPH2) 0.4089351851851852 prot_P39692 + 0.574141737891738 prot_P47169 + 4.0 H+ + 3.0 NADPH + sulphite --> 3.0 H2O + hydrogen sulfide + 3.0 NADP(+) 0.03458225817936439 r_1028 taurcholate via ABC system 571.7858889359086 prot_P32386 + ATP + H2O + taurocholate --> ADP + H+ + phosphate + taurocholate 0.0 r_1029 taurine dioxygenase 0.6971220085126848 prot_Q12358 + 2-oxoglutarate + oxygen + taurine --> aminoacetaldehyde + carbon dioxide + H+ + succinate + sulphite 0.0 r_1030 tetrahydrofolate aminomethyltransferase 0.12487609595740357 prot_P09624 + 0.0434511474046933 prot_P39726 + 0.10281642494222884 prot_P48015 + 0.2646212564047546 prot_P49095 + 5,10-methenyl-THF + H2O --> 5-formyltetrahydrofolic acid + H+ 0.0 @@ -1210,7 +1210,7 @@ r_1037_EXP_1 thioredoxin 0.16380116959064328 prot_P22803 + 0.3526315789473684 pr r_1037_EXP_2 thioredoxin 0.1642543859649123 prot_P22217 + 0.3526315789473684 prot_P40553 + H+ + hydrogen peroxide + TRX1 --> 2.0 H2O + TRX1 disulphide 0.0 r_1038_EXP_1 thioredoxin reductase (NADPH) 0.09346012679346014 prot_P22803 + 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1038_EXP_2 thioredoxin reductase (NADPH) 0.09371871871871873 prot_P22217 + 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 -r_1038_EXP_3 thioredoxin reductase (NADPH) 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.038062258209614355 +r_1038_EXP_3 thioredoxin reductase (NADPH) 0.2856022689356023 prot_P29509 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.038062258209613745 r_1039_EXP_1 thioredoxin reductase (NADPH) 0.12038705372038706 prot_P25372 + 0.3093677010343677 prot_P38816 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1039_EXP_2 thioredoxin reductase (NADPH) 0.004454320987654321 prot_P25372 + 0.016494135802469136 prot_P41921 + NADPH + TRX1 disulphide --> NADP(+) + TRX1 0.0 r_1040 threonine aldolase 0.2765826873385013 prot_P37303 + L-threonine --> acetaldehyde + L-glycine 0.0 @@ -1221,22 +1221,22 @@ r_1045 thymidylate synthase 0.20281828703703703 prot_P06785 + 5,10-methylenetetr r_1046 trans-aconitate 3-methyltransferase 147.17240726195595 prot_P32643 + S-adenosyl-L-methionine + trans-aconitate --> (2E)-3-(methoxycarbonyl)pent-2-enedioic acid + S-adenosyl-L-homocysteine 0.0 r_1047 trans-pentaprenyltranstransferase 1.43565817535086 prot_P18900 + isopentenyl diphosphate + pentaprenyl diphosphate --> diphosphate + hexaprenyl diphosphate 0.0 r_1048_EXP_1 transaldolase 0.796025641025641 prot_P53228 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.0 -r_1048_EXP_2 transaldolase 0.13717037037037036 prot_P15019 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.05531561049572159 +r_1048_EXP_2 transaldolase 0.13717037037037036 prot_P15019 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-erythrose 4-phosphate + D-fructose 6-phosphate 0.023173480662475668 r_1048_REV_EXP_1 transaldolase (reversible) 0.4518922852983988 prot_P53228 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 r_1048_REV_EXP_2 transaldolase (reversible) 0.13717037037037036 prot_P15019 + D-erythrose 4-phosphate + D-fructose 6-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 r_1049_EXP_1 transketolase 1 0.30204911433172305 prot_P33315 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.0 -r_1049_EXP_2 transketolase 1 0.2971256038647343 prot_P23254 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.05531561049572159 +r_1049_EXP_2 transketolase 1 0.2971256038647343 prot_P23254 + D-xylulose 5-phosphate + ribose-5-phosphate --> glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate 0.023173480662475668 r_1049_REV_EXP_1 transketolase 1 (reversible) 0.30204911433172305 prot_P33315 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0 r_1049_REV_EXP_2 transketolase 1 (reversible) 0.2971256038647343 prot_P23254 + glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate --> D-xylulose 5-phosphate + ribose-5-phosphate 0.0 r_1050_EXP_1 transketolase 2 0.30204911433172305 prot_P33315 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.0 r_1050_EXP_2 transketolase 2 0.2971256038647343 prot_P23254 + D-erythrose 4-phosphate + D-xylulose 5-phosphate --> D-fructose 6-phosphate + glyceraldehyde 3-phosphate 0.0 r_1050_REV_EXP_1 transketolase 2 (reversible) 0.30204911433172305 prot_P33315 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.0 -r_1050_REV_EXP_2 transketolase 2 (reversible) 0.2971256038647343 prot_P23254 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.04169659114810548 -r_1051_EXP_1 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5532575757575757 prot_P38427 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.022499309520921294 -r_1051_EXP_2 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5004419191919192 prot_P38426 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.0171001904790787 -r_1054 triose-phosphate isomerase 0.0008592271925605259 prot_P00942 + dihydroxyacetone phosphate --> glyceraldehyde 3-phosphate 4.989559479333306 +r_1050_REV_EXP_2 transketolase 2 (reversible) 0.2971256038647343 prot_P23254 + D-fructose 6-phosphate + glyceraldehyde 3-phosphate --> D-erythrose 4-phosphate + D-xylulose 5-phosphate 0.07383872098134885 +r_1051_EXP_1 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5532575757575757 prot_P38427 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.0 +r_1051_EXP_2 trehalose-phosphatase 1.3002020202020201 prot_P31688 + 1.5004419191919192 prot_P38426 + 0.708939393939394 prot_Q00764 + alpha,alpha-trehalose 6-phosphate + H2O --> phosphate + trehalose 0.039599499999999996 +r_1054 triose-phosphate isomerase 0.0008592271925605259 prot_P00942 + dihydroxyacetone phosphate --> glyceraldehyde 3-phosphate 5.0217016091666205 r_1054_REV triose-phosphate isomerase (reversible) 0.0008592271925605259 prot_P00942 + glyceraldehyde 3-phosphate --> dihydroxyacetone phosphate 0.0 -r_1055 tryptophan synthase (indoleglycerol phosphate) 0.43168564547057753 prot_P00931 + 1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> glyceraldehyde 3-phosphate + H2O + L-tryptophan 0.013075001647262715 +r_1055 tryptophan synthase (indoleglycerol phosphate) 0.43168564547057753 prot_P00931 + 1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> glyceraldehyde 3-phosphate + H2O + L-tryptophan 0.013075001647263247 r_1056 tryptophan transaminase 1.2484 prot_P53090 + 2-oxoglutarate + L-tryptophan --> indole-3-pyruvate + L-glutamate 0.0 r_1057 tryptophanyl-tRNA synthetase 0.5595238095238095 prot_Q12109 + ATP + L-tryptophan + tRNA(Trp) --> AMP + diphosphate + Trp-tRNA(Trp) 0.011185246192952879 r_1058 tryptophanyl-tRNA synthetase 0.4876984126984127 prot_P04803 + ATP + L-tryptophan + tRNA(Trp) --> AMP + diphosphate + Trp-tRNA(Trp) 0.0 @@ -1252,8 +1252,8 @@ r_1070 UDPglucose 4-epimerase 0.532373366013072 prot_P04397 + UDP-D-glucose --> r_1070_REV UDPglucose 4-epimerase (reversible) 0.532373366013072 prot_P04397 + UDP-D-galactose --> UDP-D-glucose 0.0 r_1071 UDPglucose--hexose-1-phosphate uridylyltransferase 0.3270447530864197 prot_P08431 + alpha-D-galactose 1-phosphate + UDP-D-glucose --> D-glucose 1-phosphate + UDP-D-galactose 0.0 r_1071_REV UDPglucose--hexose-1-phosphate uridylyltransferase (reversible) 0.3270447530864197 prot_P08431 + D-glucose 1-phosphate + UDP-D-galactose --> alpha-D-galactose 1-phosphate + UDP-D-glucose 0.0 -r_1072 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.0 -r_1073 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.014290109378625914 +r_1072 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.014290109378625904 +r_1073 UMP kinase 0.029356118791602662 prot_P15700 + ATP + UMP --> ADP + UDP 0.0 r_1074 uracil phosphoribosyltransferase 1.1199453551912568 prot_P18562 + PRPP + uracil --> diphosphate + UMP 0.0 r_1075 urea carboxylase 0.26596036263967954 prot_P32528 + ATP + bicarbonate + urea --> ADP + H+ + phosphate + urea-1-carboxylic acid 0.0 r_1076 ureidoglycolate hydrolase 335.29320987654324 prot_P32459 + 2.0 H+ + H2O + ureidoglycolic acid --> 2.0 ammonium + carbon dioxide + glyoxylate 0.0 @@ -1274,10 +1274,10 @@ r_1085_EXP_1 V-ATPase, Golgi 0.0066673789173789175 prot_P0C5R9 + 0.1233952991452 r_1085_EXP_2 V-ATPase, Golgi 0.04113176638176638 prot_P16140 + 0.08449928774928775 prot_P17255 + 0.018853988603988604 prot_P22203 + 0.016094017094017095 prot_P23968 + 0.011646011396011397 prot_P25515 + 0.03147364672364673 prot_P31412 + 0.02834116809116809 prot_P32366 + 0.020793447293447294 prot_P32610 + 0.012134615384615384 prot_P32842 + 0.07240811965811966 prot_P37296 + 0.009587606837606838 prot_P39111 + 0.03875783475783476 prot_P41807 + 0.009054843304843305 prot_P48836 + 0.021138176638176638 prot_P53262 + 0.005969373219373219 prot_Q3E7B6 + ATP + H+ + H2O --> ADP + 2.0 H+ + phosphate 0.0 r_1086_EXP_1 V-ATPase, vacuole 0.0066673789173789175 prot_P0C5R9 + 0.12339529914529915 prot_P16140 + 0.2534978632478633 prot_P17255 + 0.05656196581196581 prot_P22203 + 0.016094017094017095 prot_P23968 + 0.09316809116809117 prot_P25515 + 0.03147364672364673 prot_P31412 + 0.02834116809116809 prot_P32366 + 0.06804059829059829 prot_P32563 + 0.020793447293447294 prot_P32610 + 0.012134615384615384 prot_P32842 + 0.009587606837606838 prot_P39111 + 0.03875783475783476 prot_P41807 + 0.027164529914529913 prot_P48836 + 0.021138176638176638 prot_P53262 + 0.005969373219373219 prot_Q3E7B6 + ATP + H+ + H2O --> ADP + 2.0 H+ + phosphate 0.0 r_1086_EXP_2 V-ATPase, vacuole 0.04113176638176638 prot_P16140 + 0.08449928774928775 prot_P17255 + 0.018853988603988604 prot_P22203 + 0.016094017094017095 prot_P23968 + 0.011646011396011397 prot_P25515 + 0.03147364672364673 prot_P31412 + 0.02834116809116809 prot_P32366 + 0.06804059829059829 prot_P32563 + 0.020793447293447294 prot_P32610 + 0.012134615384615384 prot_P32842 + 0.009587606837606838 prot_P39111 + 0.03875783475783476 prot_P41807 + 0.009054843304843305 prot_P48836 + 0.021138176638176638 prot_P53262 + 0.005969373219373219 prot_Q3E7B6 + ATP + H+ + H2O --> ADP + 2.0 H+ + phosphate 0.0 -r_1087 valine transaminase 0.009354773462783171 prot_P47176 + 2-oxoglutarate + L-valine --> 3-methyl-2-oxobutanoate + L-glutamate 0.10513175524287399 +r_1087 valine transaminase 0.009354773462783171 prot_P47176 + 2-oxoglutarate + L-valine --> 3-methyl-2-oxobutanoate + L-glutamate 0.10513175524407464 r_1087_REV valine transaminase (reversible) 0.010755813953488373 prot_P47176 + 3-methyl-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-valine 0.0 r_1088 valine transaminase, mitochondiral 0.009797734627831714 prot_P38891 + 2-oxoglutarate + L-valine --> 3-methyl-2-oxobutanoate + L-glutamate 0.0 -r_1088_REV valine transaminase, mitochondiral (reversible) 0.011265116279069768 prot_P38891 + 3-methyl-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-valine 0.1963670746775834 +r_1088_REV valine transaminase, mitochondiral (reversible) 0.011265116279069768 prot_P38891 + 3-methyl-2-oxobutanoate + L-glutamate --> 2-oxoglutarate + L-valine 0.19636707467878406 r_1089 valyl-tRNA synthetase 0.6987222222222222 prot_P07806 + ATP + L-valine + tRNA(Val) --> AMP + diphosphate + Val-tRNA(Val) 0.0912353194347094 r_1090 valyl-tRNA synthetase 0.6987222222222222 prot_P07806 + ATP + L-valine + tRNA(Val) --> AMP + diphosphate + Val-tRNA(Val) 0.0 r_1091 xanthine phosphoribosyltransferase 1.5042841315863547 prot_P47165 + 9H-xanthine + PRPP --> diphosphate + xanthosine-5-phosphate 0.0 @@ -1313,23 +1313,23 @@ r_1103_REV 5-formyltetrahydrofolic acid transport (reversible) 5-formyltetrahydr r_1104 8-Amino-7-oxononanoate transport 1.86456462002342 prot_P53744 + 8-amino-7-oxononanoate + H+ --> 8-amino-7-oxononanoate + H+ 0.0 r_1106 acetate transport 0.7536246695645853 prot_P25613 + acetate --> acetate 0.7284976164000001 r_1106_REV acetate transport (reversible) 0.7536246695645853 prot_P25613 + acetate --> acetate 0.0 -r_1107 acetic ester transport ethyl acetate --> ethyl acetate 0.0 +r_1107 acetic ester transport ethyl acetate --> ethyl acetate 0.39888062410379055 r_1108_EXP_1 adenine transport 13.568751070237582 prot_P17064 + adenine + H+ --> adenine + H+ 0.0 r_1108_EXP_2 adenine transport 96.43325000488205 prot_P40039 + adenine + H+ --> adenine + H+ 0.0 r_1108_EXP_3 adenine transport 170.37838815188596 prot_Q12119 + adenine + H+ --> adenine + H+ 0.0 r_1109 adenosine transport 38.061322453849215 prot_P31381 + adenosine + H+ --> adenosine + H+ 0.0 r_1110_EXP_1 ADP/ATP transporter 0.06555300613384876 prot_P18239 + ADP + ATP --> ADP + ATP 0.0 -r_1110_EXP_2 ADP/ATP transporter 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 19.074034537486224 +r_1110_EXP_2 ADP/ATP transporter 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 19.138677200602803 r_1110_EXP_3 ADP/ATP transporter 0.045422922213833025 prot_P04710 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_1 ADP/ATP transporter (reversible) 0.06555300613384876 prot_P18239 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_2 ADP/ATP transporter (reversible) 0.029890785485312033 prot_P18238 + ADP + ATP --> ADP + ATP 0.0 r_1110_REV_EXP_3 ADP/ATP transporter (reversible) 0.045422922213833025 prot_P04710 + ADP + ATP --> ADP + ATP 0.0 r_1111 ADP/ATP transporter 1.0879458482506026 prot_Q06497 + ADP + ATP + H+ --> ADP + ATP + H+ 0.0 -r_1112 AKG transporter, mitochonrial 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 1.818192190428221 +r_1112 AKG transporter, mitochonrial 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 1.6100444102941618 r_1112_REV AKG transporter, mitochonrial (reversible) 0.06308457229795243 prot_Q04013 + 2-oxoglutarate + citrate --> 2-oxoglutarate + citrate 0.0 r_1113 allantoate uniport 1.2976708311906466 prot_P15365 + allantoate --> allantoate 0.0 r_1114 allantoin uniport 10.243314336688835 prot_Q04895 + allantoin --> allantoin 0.0 -r_1115_EXP_1 ammonia transport 0.565835007774522 prot_Q12359 + ammonium --> ammonium 1.907574941909046 +r_1115_EXP_1 ammonia transport 0.565835007774522 prot_Q12359 + ammonium --> ammonium 1.9075749419090673 r_1115_EXP_2 ammonia transport 1.0213597006592061 prot_P40260 + ammonium --> ammonium 0.0 r_1115_EXP_3 ammonia transport 1.006265993411724 prot_P41948 + ammonium --> ammonium 0.0 r_1115_EXP_4 ammonia transport 1.0117117879117519 prot_P53390 + ammonium --> ammonium 0.0 @@ -1351,12 +1351,12 @@ r_1124 ceramide-3 (Phytosphingosine:n-C26:0OH) transport ceramide-3 (C26) --> ce r_1124_REV ceramide-3 (Phytosphingosine:n-C26:0OH) transport (reversible) ceramide-3 (C26) --> ceramide-3 (C26) 0.0 r_1125 choline transport 49.19344031664132 prot_P19807 + choline + H+ --> choline + H+ 0.0 r_1126 citrate transport 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.0 -r_1126_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.586743028687102 +r_1126_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + (S)-malate + citrate --> (S)-malate + citrate 0.5877833817459681 r_1127 citrate transport 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.0 -r_1127_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.09701220164382707 +r_1127_REV citrate transport (reversible) 0.4084348057672835 prot_P38152 + citrate + phosphoenolpyruvate --> citrate + phosphoenolpyruvate 0.09701220164382451 r_1128 citrate transport 0.3417805406736961 prot_P38152 + citrate + isocitrate --> citrate + isocitrate 0.0 r_1128_REV citrate transport (reversible) 0.3417805406736961 prot_P38152 + citrate + isocitrate --> citrate + isocitrate 0.0 -r_1129 coenzyme A transport 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.06416760246059915 +r_1129 coenzyme A transport 0.1723508574845098 prot_P38702 + coenzyme A --> coenzyme A 0.06365104804868436 r_1130 CTP transport 0.2701553629071786 prot_P38127 + CMP + CTP + H+ --> CMP + CTP + H+ 0.0 r_1131 CTP/CMP antiport 0.2701553629071786 prot_P38127 + CMP + CTP + 2.0 H+ --> CMP + CTP + 2.0 H+ 0.0 r_1132 cytidine transport 19.950758151174124 prot_P31381 + cytidine + H+ --> cytidine + H+ 0.0 @@ -1385,9 +1385,9 @@ r_1135_EXP_3 D-galactose transport 7.895711187219881 prot_P13181 + D-galactose + r_1135_EXP_4 D-galactose transport 9.049001302171312 prot_P42833 + D-galactose + H+ --> D-galactose + H+ 0.0 r_1135_EXP_5 D-galactose transport 0.8760873219329858 prot_P54862 + D-galactose + H+ --> D-galactose + H+ 0.0 r_1136 D-lactate transport 1398.5378967792055 prot_P36035 + (R)-lactate + H+ --> (R)-lactate + H+ 0.0 -r_1137 D-lactate transport (R)-lactate + H+ --> (R)-lactate + H+ 0.7807991710272227 +r_1137 D-lactate transport (R)-lactate + H+ --> (R)-lactate + H+ 2.280285835846048 r_1138 D-lactate/pyruvate antiport (R)-lactate + pyruvate --> (R)-lactate + pyruvate 0.0 -r_1138_REV D-lactate/pyruvate antiport (reversible) (R)-lactate + pyruvate --> (R)-lactate + pyruvate 0.7807991710272227 +r_1138_REV D-lactate/pyruvate antiport (reversible) (R)-lactate + pyruvate --> (R)-lactate + pyruvate 2.280285835846048 r_1139_EXP_1 D-mannose transport 21.752276959457756 prot_P54854 + D-mannose + H+ --> D-mannose + H+ 0.0 r_1139_EXP_10 D-mannose transport 5.737789186505133 prot_P40885 + D-mannose + H+ --> D-mannose + H+ 0.0 r_1139_EXP_11 D-mannose transport 24.62776935429521 prot_P47185 + D-mannose + H+ --> D-mannose + H+ 0.0 @@ -1415,7 +1415,7 @@ r_1148_REV_EXP_1 ergosterol transport (reversible) 220.04126278706457 prot_P4055 r_1148_REV_EXP_2 ergosterol transport (reversible) 300.989150017774 prot_Q08409 + ergosterol --> ergosterol 0.0 r_1149 ethanolamine transport 19.35463221575592 prot_P19807 + ethanolamine --> ethanolamine 0.0 r_1149_REV ethanolamine transport (reversible) 19.35463221575592 prot_P19807 + ethanolamine --> ethanolamine 0.0 -r_1151 fadH2 transport 2.2694626476781234 prot_P40464 + FADH2 --> FADH2 0.0 +r_1151 fadH2 transport 2.2694626476781234 prot_P40464 + FADH2 --> FADH2 2.8999999267398372e-06 r_1161_EXP_1 fecosterol transport 202.39396969322675 prot_P40550 + fecosterol --> fecosterol 0.0 r_1161_EXP_2 fecosterol transport 242.95341636695454 prot_Q08409 + fecosterol --> fecosterol 0.0 r_1161_REV_EXP_1 fecosterol transport (reversible) 202.39396969322675 prot_P40550 + fecosterol --> fecosterol 0.0 @@ -1467,7 +1467,7 @@ r_1173_EXP_3 glycine transport 12.596301854889402 prot_P38967 + H+ + L-glycine - r_1173_EXP_4 glycine transport 14.445193920799005 prot_P15380 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_EXP_5 glycine transport 7.968919773312661 prot_P53388 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_1 glycine transport (reversible) 25.955237884466197 prot_P25376 + H+ + L-glycine --> H+ + L-glycine 0.0 -r_1173_REV_EXP_2 glycine transport (reversible) 4.0449974975144505 prot_P19145 + H+ + L-glycine --> H+ + L-glycine 0.021977569649902398 +r_1173_REV_EXP_2 glycine transport (reversible) 4.0449974975144505 prot_P19145 + H+ + L-glycine --> H+ + L-glycine 0.021977569649953704 r_1173_REV_EXP_3 glycine transport (reversible) 12.596301854889402 prot_P38967 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_4 glycine transport (reversible) 14.445193920799005 prot_P15380 + H+ + L-glycine --> H+ + L-glycine 0.0 r_1173_REV_EXP_5 glycine transport (reversible) 9.41498101418254 prot_P53388 + H+ + L-glycine --> H+ + L-glycine 0.0 @@ -1516,7 +1516,7 @@ r_1192_EXP_5 L-cystine transport 3.8637388807060162 prot_P48813 + H+ + L-cystein r_1192_EXP_6 L-cystine transport 2.0808020354818835 prot_P19145 + H+ + L-cysteine --> H+ + L-cysteine 0.0 r_1192_EXP_7 L-cystine transport 4.954940745719529 prot_P38967 + H+ + L-cysteine --> H+ + L-cysteine 0.0 r_1193 L-cystine transport 7.973877475373074 prot_P17261 + H+ + L-cystine --> H+ + L-cystine 0.0 -r_1194 L-glutamate transport 1.8810464305164725 prot_Q12482 + L-glutamate --> L-glutamate 0.3771414474880992 +r_1194 L-glutamate transport 1.8810464305164725 prot_Q12482 + L-glutamate --> L-glutamate 0.37714144748929984 r_1195 L-glutamate transport 51.467278676926874 prot_P40074 + H+ + L-glutamate --> H+ + L-glutamate 0.0 r_1196_EXP_1 L-glutamate transport 7.883394470362304 prot_P25376 + H+ + L-glutamate --> H+ + L-glutamate 0.0 r_1196_EXP_2 L-glutamate transport 92.56119945738607 prot_P43548 + H+ + L-glutamate --> H+ + L-glutamate 0.0 @@ -1637,13 +1637,13 @@ r_1241 pantothenate transport 34.938176452130854 prot_P25621 + (R)-pantothenate r_1242 pentaprenyl diphosphate transport pentaprenyl diphosphate --> pentaprenyl diphosphate 0.0 r_1242_REV pentaprenyl diphosphate transport (reversible) pentaprenyl diphosphate --> pentaprenyl diphosphate 0.0 r_1243 phenethyl acetate transport phenethyl acetate --> phenethyl acetate 0.0 -r_1244_EXP_1 phosphate transport 1.5821717171717171 prot_P38361 + H+ + phosphate --> H+ + phosphate 0.08106295972630928 +r_1244_EXP_1 phosphate transport 1.5821717171717171 prot_P38361 + H+ + phosphate --> H+ + phosphate 0.08106295972626476 r_1244_EXP_2 phosphate transport 2.5893939393939394 prot_P25360 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_3 phosphate transport 2.4668939393939393 prot_P39535 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_4 phosphate transport 1.6258080808080808 prot_P25297 + H+ + phosphate --> H+ + phosphate 0.0 r_1244_EXP_5 phosphate transport 2.5123737373737374 prot_P27514 + H+ + phosphate --> H+ + phosphate 0.0 -r_1245_EXP_1 phosphate transport 0.8466666666666667 prot_P40035 + H+ + phosphate --> H+ + phosphate 0.03147364420221521 -r_1245_EXP_2 phosphate transport 0.8285858585858585 prot_P23641 + H+ + phosphate --> H+ + phosphate 0.6774665112162245 +r_1245_EXP_1 phosphate transport 0.8466666666666667 prot_P40035 + H+ + phosphate --> H+ + phosphate 0.0 +r_1245_EXP_2 phosphate transport 0.8285858585858585 prot_P23641 + H+ + phosphate --> H+ + phosphate 0.3900122826157002 r_1249_EXP_1 potassium transport 1.7714141414141413 prot_Q04121 + H+ + potassium --> H+ + potassium 0.0010526999807916584 r_1249_EXP_2 potassium transport 3.562449494949495 prot_P12685 + H+ + potassium --> H+ + potassium 0.0 r_1250 putrescine excretion 14.581286007528888 prot_P36029 + putrescine --> putrescine 0.0 @@ -1687,8 +1687,8 @@ r_1263_REV_EXP_2 spermine transport (reversible) 14.118248201928578 prot_Q07824 r_1263_REV_EXP_3 spermine transport (reversible) 4.735615277275769 prot_Q12256 + H+ + spermine --> H+ + spermine 0.0 r_1263_REV_EXP_4 spermine transport (reversible) 5.6450672243090425 prot_Q06451 + H+ + spermine --> H+ + spermine 0.0 r_1264 succinate transport 0.32879485380079526 prot_Q06143 + phosphate + succinate --> phosphate + succinate 0.0 -r_1265 succinate-fumarate transport 0.5875590154537462 prot_P33303 + fumarate + succinate --> fumarate + succinate 0.031107817482281964 -r_1266_EXP_1 sulfate uniport 2.4230050505050507 prot_P38359 + sulphate --> sulphate 0.04038225804972491 +r_1265 succinate-fumarate transport 0.5875590154537462 prot_P33303 + fumarate + succinate --> fumarate + succinate 0.03165038721698816 +r_1266_EXP_1 sulfate uniport 2.4230050505050507 prot_P38359 + sulphate --> sulphate 0.0403822580497243 r_1266_EXP_2 sulfate uniport 2.516439393939394 prot_Q12325 + sulphate --> sulphate 0.0 r_1267 sulfite transport 296.1052693373152 prot_P41930 + sulphite --> sulphite 0.0 r_1268 taurine transport taurine --> taurine 0.0 @@ -1705,7 +1705,7 @@ r_1275 UTP transport 0.3655624733979681 prot_P38127 + FMN + H+ + UMP + UTP --> F r_1276 UTP/UMP antiport 0.3655624733979681 prot_P38127 + 2.0 H+ + UMP + UTP --> 2.0 H+ + UMP + UTP 0.0 r_1277_EXP_1 water diffusion 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_1277_EXP_2 water diffusion 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_1277_REV_EXP_1 water diffusion (reversible) 0.4050171892049932 prot_P0CD90 + H2O --> H2O 13.997537829919185 +r_1277_REV_EXP_1 water diffusion (reversible) 0.4050171892049932 prot_P0CD90 + H2O --> H2O 13.518999487189447 r_1277_REV_EXP_2 water diffusion (reversible) 0.77827345573678 prot_P0CD91 + H2O --> H2O 0.0 r_1278_EXP_1 zymosterol transport 187.19737369610002 prot_P40550 + zymosterol --> zymosterol 0.0 r_1278_EXP_2 zymosterol transport 254.30179320863886 prot_Q08409 + zymosterol --> zymosterol 0.0 @@ -1763,9 +1763,9 @@ r_1564 2'-deoxyguanosine exchange 2'-deoxyguanosine --> 0.0 r_1565 2'-deoxyinosine exchange 2'-deoxyinosine --> 0.0 r_1566 2'-deoxyuridine exchange 2'-deoxyuridine --> 0.0 r_1567 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.0 -r_1567_REV 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport (reversible) 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.09701220164382707 +r_1567_REV 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport (reversible) 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid --> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid 0.09701220164382451 r_1568 2-dehydropantoate transport 2-dehydropantoate --> 2-dehydropantoate 0.0 -r_1568_REV 2-dehydropantoate transport (reversible) 2-dehydropantoate --> 2-dehydropantoate 5.510000177322283e-05 +r_1568_REV 2-dehydropantoate transport (reversible) 2-dehydropantoate --> 2-dehydropantoate 5.5100001772612206e-05 r_1572 2-isopropylmalate exchange 2-isopropylmalate --> 0.0 r_1573 2-isopropylmalate transport 2-isopropylmalate --> 2-isopropylmalate 0.0 r_1573_REV 2-isopropylmalate transport (reversible) 2-isopropylmalate --> 2-isopropylmalate 0.0 @@ -1782,7 +1782,7 @@ r_1579 2-methylbutanal transport 2-methylbutanal --> 2-methylbutanal 0.0 r_1579_REV 2-methylbutanal transport (reversible) 2-methylbutanal --> 2-methylbutanal 0.0 r_1580 2-methylbutanol exchange 2-methylbutanol --> 0.0 r_1581 2-methylbutyl acetate exchange 2-methylbutyl acetate --> 0.0 -r_1582 2-methylpropanal transport isobutyraldehyde --> isobutyraldehyde -1.2006506899808755e-12 +r_1582 2-methylpropanal transport isobutyraldehyde --> isobutyraldehyde 0.0 r_1582_REV 2-methylpropanal transport (reversible) isobutyraldehyde --> isobutyraldehyde 0.0 r_1583 2-methylpropanal transport isobutyraldehyde --> isobutyraldehyde 0.0 r_1583_REV 2-methylpropanal transport (reversible) isobutyraldehyde --> isobutyraldehyde 0.0 @@ -1790,11 +1790,11 @@ r_1585_EXP_1 2-oxobutanoate transporter 3.025147963735379 prot_P53943 + 2-oxobut r_1585_EXP_2 2-oxobutanoate transporter 39.053720824554496 prot_P36035 + 2-oxobutanoate --> 2-oxobutanoate 0.0 r_1585_REV_EXP_1 2-oxobutanoate transporter (reversible) 3.025147963735379 prot_P53943 + 2-oxobutanoate --> 2-oxobutanoate 0.0 r_1585_REV_EXP_2 2-oxobutanoate transporter (reversible) 39.053720824554496 prot_P36035 + 2-oxobutanoate --> 2-oxobutanoate 0.0 -r_1586 2-oxoglutarate exchange 2-oxoglutarate --> 0.0 +r_1586 2-oxoglutarate exchange 2-oxoglutarate --> -3.151645611154663e-13 r_1587 2-oxoglutarate transport 2-oxoglutarate --> 2-oxoglutarate 0.0 r_1587_REV 2-oxoglutarate transport (reversible) 2-oxoglutarate --> 2-oxoglutarate 0.0 r_1588 2-oxoglutarate transport 2-oxoglutarate --> 2-oxoglutarate 0.0 -r_1588_REV 2-oxoglutarate transport (reversible) 2-oxoglutarate --> 2-oxoglutarate 0.0 +r_1588_REV 2-oxoglutarate transport (reversible) 2-oxoglutarate --> 2-oxoglutarate -3.151645611154663e-13 r_1589 2-phenylethanol exchange 2-phenylethanol --> 0.0 r_1590 2-phenylethanol transport 2-phenylethanol --> 2-phenylethanol 0.0 r_1590_REV 2-phenylethanol transport (reversible) 2-phenylethanol --> 2-phenylethanol 0.0 @@ -1852,11 +1852,11 @@ r_1628 7,8-diaminononanoate transport 7,8-diaminononanoate --> 7,8-diaminononano r_1628_REV 7,8-diaminononanoate transport (reversible) 7,8-diaminononanoate --> 7,8-diaminononanoate 0.0 r_1629 8-amino-7-oxononanoate exchange 8-amino-7-oxononanoate --> 0.0 r_1630 9H-xanthine exchange 9H-xanthine --> 0.0 -r_1631 acetaldehyde exchange acetaldehyde --> 0.30440001004043893 +r_1631 acetaldehyde exchange acetaldehyde --> 0.0 r_1632 acetaldehyde transport acetaldehyde --> acetaldehyde 0.0 -r_1632_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 2.2892737555003304 +r_1632_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.5822182091973631 r_1633 acetaldehyde transport acetaldehyde --> acetaldehyde 0.0 -r_1633_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.30440001004043893 +r_1633_REV acetaldehyde transport (reversible) acetaldehyde --> acetaldehyde 0.0 r_1634 acetate exchange acetate --> 0.7284976164000001 r_1635 acetate transport acetate --> acetate 0.0 r_1635_REV acetate transport (reversible) acetate --> acetate 0.0 @@ -1868,10 +1868,10 @@ r_1640 adenine transport adenine --> adenine 0.0 r_1640_REV adenine transport (reversible) adenine --> adenine 0.0 r_1641 adenosine 3',5'-bismonophosphate exchange adenosine 3',5'-bismonophosphate --> 0.0 r_1642 adenosine 3',5'-bisphosphate transport 0.12463347770546829 prot_Q12251 + adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0 -r_1642_REV adenosine 3',5'-bisphosphate transport (reversible) 0.12463347770546829 prot_Q12251 + adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0 +r_1642_REV adenosine 3',5'-bisphosphate transport (reversible) 0.12463347770546829 prot_Q12251 + adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0004426833214992709 r_1643 adenosine exchange adenosine --> 0.0 r_1644 ADP transport ADP --> ADP 0.0 -r_1644_REV ADP transport (reversible) ADP --> ADP 0.014290109378625914 +r_1644_REV ADP transport (reversible) ADP --> ADP 0.0 r_1645 ADP transport ADP --> ADP 0.0 r_1645_REV ADP transport (reversible) ADP --> ADP 0.0 r_1647 AKG transporter, peroxisome 2-oxoglutarate --> 2-oxoglutarate 0.0 @@ -1882,14 +1882,14 @@ r_1650 trehalose exchange trehalose --> 0.0 r_1651 alpha-D-glucosamine 6-phosphate exchange alpha-D-glucosamine 6-phosphate --> 0.0 r_1652 alpha-ketoglutarate/malate transporter (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 r_1652_REV alpha-ketoglutarate/malate transporter (reversible) (S)-malate + 2-oxoglutarate --> (S)-malate + 2-oxoglutarate 0.0 -r_1654 ammonium exchange ammonium <=> -1.907574941909046 +r_1654 ammonium exchange ammonium <=> -1.9075749419090673 r_1656 AMP transport AMP --> AMP 0.0 r_1656_REV AMP transport (reversible) AMP --> AMP 0.0 r_1657 arginine transport 25.141189431578304 prot_P38279 + H+ + L-arginine --> H+ + L-arginine 0.0 r_1658 asparagine transport 5.8602645666708675 prot_P48813 + L-asparagine --> L-asparagine 0.0 r_1659 aspartate-glutamate transporter L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 r_1659_REV aspartate-glutamate transporter (reversible) L-aspartate + L-glutamate --> L-aspartate + L-glutamate 0.0 -r_1660 ATP diffusion ATP --> ATP 0.014290109378625914 +r_1660 ATP diffusion ATP --> ATP 0.0 r_1660_REV ATP diffusion (reversible) ATP --> ATP 0.0 r_1661 ATP transport ATP --> ATP 0.0 r_1661_REV ATP transport (reversible) ATP --> ATP 0.0 @@ -1898,7 +1898,7 @@ r_1664 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + r_1664_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1665 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + H2O --> bicarbonate + H+ 0.0 r_1665_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 -r_1667 bicarbonate formation 7.346040189125295e-06 prot_P53615 + carbon dioxide + H2O --> bicarbonate + H+ 1.8577375929351163 +r_1667 bicarbonate formation 7.346040189125295e-06 prot_P53615 + carbon dioxide + H2O --> bicarbonate + H+ 1.6234420774788973 r_1667_REV bicarbonate formation (reversible) 7.346040189125295e-06 prot_P53615 + bicarbonate + H+ --> carbon dioxide + H2O 0.0 r_1668 bicarbonate formation 1.1329040404040405 prot_standard + carbon dioxide + H2O --> bicarbonate + H+ 0.0 r_1668_REV bicarbonate formation (reversible) 1.1329040404040405 prot_standard + bicarbonate + H+ --> carbon dioxide + H2O 0.0 @@ -1925,7 +1925,7 @@ r_1681_REV ceramide transport (reversible) ceramide-4 (C26) --> ceramide-4 (C26) r_1682 cholestenol delta-isomerase, lumped reaction 2.489610027058053 prot_standard + oxygen + S-adenosyl-L-methionine + zymosterol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H+ + 2.0 H2O + S-adenosyl-L-homocysteine 0.010694455410100273 r_1683 choline exchange choline --> 0.0 r_1684_EXP_1 choline transport 49.19344031664132 prot_P19807 + choline --> choline 0.0 -r_1684_EXP_2 choline transport 4.890140948879145 prot_Q12412 + choline --> choline 0.010068800024351886 +r_1684_EXP_2 choline transport 4.890140948879145 prot_Q12412 + choline --> choline 0.0100688000243519 r_1684_REV_EXP_1 choline transport (reversible) 49.19344031664132 prot_P19807 + choline --> choline 0.0 r_1684_REV_EXP_2 choline transport (reversible) 4.890140948879145 prot_Q12412 + choline --> choline 0.0 r_1685 chorismate pyruvate lyase 0.6162073031087573 prot_standard + chorismate --> 4-hydroxybenzoate + pyruvate 0.0 @@ -1944,17 +1944,17 @@ r_1694_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1695 CO2 transport carbon dioxide --> carbon dioxide 0.0 r_1695_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1696 CO2 transport carbon dioxide --> carbon dioxide 0.0 -r_1696_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 3.164331142353359 +r_1696_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 4.456131481450676 r_1697 CO2 transport carbon dioxide --> carbon dioxide 11.915897634 r_1697_REV CO2 transport (reversible) carbon dioxide --> carbon dioxide 0.0 r_1698 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1698_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 r_1699 coenzyme A transport coenzyme A --> coenzyme A 0.0 r_1699_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 -r_1700 coenzyme A transport coenzyme A --> coenzyme A 0.0 +r_1700 coenzyme A transport coenzyme A --> coenzyme A 3.922891305596643e-05 r_1700_REV coenzyme A transport (reversible) coenzyme A --> coenzyme A 0.0 r_1702 cytidine exchange cytidine --> 0.0 -r_1703 cytidylate kinase (CMP) 0.015537262872628726 prot_P15700 + ATP + CMP --> ADP + CDP 0.015318034372840194 +r_1703 cytidylate kinase (CMP) 0.015537262872628726 prot_P15700 + ATP + CMP --> ADP + CDP 0.015318034372839573 r_1704 cytidylate kinase (dCMP) 0.0872640791476408 prot_P15700 + ATP + dCMP --> ADP + dCDP 0.0 r_1704_REV cytidylate kinase (dCMP) (reversible) 0.6446121633029441 prot_P15700 + ADP + dCDP --> ATP + dCMP 0.0017400000151246773 r_1705 cytosine exchange cytosine --> 0.0 @@ -1963,7 +1963,7 @@ r_1707_EXP_1 D-arabinose transport 12.279417568370668 prot_P39004 + D-arabinose r_1707_EXP_2 D-arabinose transport 21.95512360185767 prot_P32467 + D-arabinose --> D-arabinose 0.0 r_1707_REV_EXP_1 D-arabinose transport (reversible) 12.279417568370668 prot_P39004 + D-arabinose --> D-arabinose 0.0 r_1707_REV_EXP_2 D-arabinose transport (reversible) 21.95512360185767 prot_P32467 + D-arabinose --> D-arabinose 0.0 -r_1708 D-erythrose 4-phosphate transport D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.09701220164382707 +r_1708 D-erythrose 4-phosphate transport D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.09701220164382451 r_1708_REV D-erythrose 4-phosphate transport (reversible) D-erythrose 4-phosphate --> D-erythrose 4-phosphate 0.0 r_1709 D-fructose exchange D-fructose --> 0.0 r_1710 D-galactose exchange D-galactose --> 0.0 @@ -2005,7 +2005,7 @@ r_1732 deoxyguanosine transport 2'-deoxyguanosine --> 2'-deoxyguanosine 0.0 r_1733 deoxyinosine transport 2'-deoxyinosine --> 2'-deoxyinosine 0.0 r_1734 deoxyuridine kinase (ATP:deoxyuridine) 0.9660422049956934 prot_standard + 2'-deoxyuridine + ATP --> ADP + dUMP + H+ 0.0 r_1735 deoxyuridine transport 3.240537611534019 prot_P38196 + 2'-deoxyuridine --> 2'-deoxyuridine 0.0 -r_1736 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 5.510000177322283e-05 +r_1736 dephospho-CoA kinase 1.3634550169559145 prot_Q03941 + 3'-dephospho-CoA + ATP --> ADP + coenzyme A + H+ 0.0 r_1737 dGDP transport dGDP --> dGDP 0.0 r_1737_REV dGDP transport (reversible) dGDP --> dGDP 0.0 r_1738 dhnpt transport 7,8-dihydroneopterin --> 7,8-dihydroneopterin 1.83860007382311e-05 @@ -2016,7 +2016,7 @@ r_1743_REV dihydrofolate transport (reversible) dihydrofolic acid --> dihydrofol r_1744 dihydroneopterin triphosphate pyrophosphatase 6.230972222222222 prot_standard + 7,8-dihydroneopterin 3'-triphosphate + H2O --> 7,8-dihydroneopterin 3'-phosphate + diphosphate + H+ 0.0 r_1745 dihydropteroate transport 7,8-dihydropteroate --> 7,8-dihydropteroate 0.0 r_1745_REV dihydropteroate transport (reversible) 7,8-dihydropteroate --> 7,8-dihydropteroate 1.83860007382311e-05 -r_1746 dihydroxyacetone phosphate transport dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 +r_1746 dihydroxyacetone phosphate transport dihydroxyacetone phosphate --> dihydroxyacetone phosphate 2.8999999267398372e-06 r_1746_REV dihydroxyacetone phosphate transport (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_1747 diphosphate transport diphosphate --> diphosphate 0.0 r_1747_REV diphosphate transport (reversible) diphosphate --> diphosphate 0.0 @@ -2033,7 +2033,7 @@ r_1753 episterol exchange episterol --> 0.0 r_1754 ergosta-5,6,22,24,(28)-tetraen-3beta-ol transport ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.010694455410100273 r_1754_REV ergosta-5,6,22,24,(28)-tetraen-3beta-ol transport (reversible) ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 r_1757 ergosterol exchange ergosterol --> 0.0 -r_1758 ergosterol transport ergosterol --> ergosterol 0.0 +r_1758 ergosterol transport ergosterol --> ergosterol 0.007709041072055719 r_1758_REV ergosterol transport (reversible) ergosterol --> ergosterol 0.0 r_1759 ergosterol transport ergosterol --> ergosterol 0.0 r_1759_REV ergosterol transport (reversible) ergosterol --> ergosterol 0.0 @@ -2043,7 +2043,7 @@ r_1762_REV ethanol transport (reversible) ethanol --> ethanol 0.0 r_1763 ethanol transport, mitochondrial ethanol --> ethanol 0.0 r_1763_REV ethanol transport, mitochondrial (reversible) ethanol --> ethanol 0.0 r_1764 ethanolamine exchange ethanolamine --> 0.0 -r_1765 ethyl acetate exchange ethyl acetate --> 0.0 +r_1765 ethyl acetate exchange ethyl acetate --> 0.39888062410379055 r_1766 farnesyl diphosphate transport farnesyl diphosphate --> farnesyl diphosphate 2.899999992678204e-07 r_1766_REV farnesyl diphosphate transport (reversible) farnesyl diphosphate --> farnesyl diphosphate 0.0 r_1770 fatty acid transport 0.6366271866276696 prot_P38225 + decanoate --> decanoate 0.0 @@ -2061,7 +2061,7 @@ r_1776_REV fatty acid transport (reversible) octanoate --> octanoate 0.0 r_1777 myristate (n-C14:0) transport myristate --> myristate 0.0 r_1777_REV myristate (n-C14:0) transport (reversible) myristate --> myristate 0.0 r_1788 fecosterol exchange fecosterol --> 0.0 -r_1790 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 0.0 +r_1790 FMN adenylyltransferase 110.94257178526843 prot_P38913 + ATP + FMN + H+ --> diphosphate + FAD 2.8999999267398372e-06 r_1791 FMN exchange FMN --> 0.0 r_1792 folic acid exchange folate --> 0.0 r_1793 formate exchange formate --> 0.0 @@ -2084,11 +2084,11 @@ r_1805_REV glucose transport, vacuolar (reversible) 8.708548007139461 prot_P3814 r_1806 glutathione disulfide exchange glutathione disulfide --> 0.0 r_1807 glutathione exchange glutathione --> 0.0 r_1808 glycerol exchange glycerol --> 0.0 -r_1809 glycerol-3-phosphate shuttle glycerol 3-phosphate --> glycerol 3-phosphate 0.0 +r_1809 glycerol-3-phosphate shuttle glycerol 3-phosphate --> glycerol 3-phosphate 2.8999999267398372e-06 r_1809_REV glycerol-3-phosphate shuttle (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 -r_1810 L-glycine exchange L-glycine --> 0.021977569649902398 +r_1810 L-glycine exchange L-glycine --> 0.021977569649953704 r_1811 glycine transport 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 0.0 -r_1811_REV glycine transport (reversible) 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 5.2780001779080273e-05 +r_1811_REV glycine transport (reversible) 8.291953599873949 prot_P32331 + L-glycine --> L-glycine 5.278000177846965e-05 r_1812 glycoaldehyde transport glycolaldehyde --> glycolaldehyde 0.0 r_1812_REV glycoaldehyde transport (reversible) glycolaldehyde --> glycolaldehyde 1.83860007382311e-05 r_1813 glycoaldehyde transport glycolaldehyde --> glycolaldehyde 0.0 @@ -2119,7 +2119,7 @@ r_1830 H+ diffusion H+ --> H+ 0.0 r_1830_REV H+ diffusion (reversible) H+ --> H+ 0.0 r_1831 H+ diffusion H+ --> H+ 0.0 r_1831_REV H+ diffusion (reversible) H+ --> H+ 0.0 -r_1832 H+ exchange H+ <=> 3.560415622316908 +r_1832 H+ exchange H+ <=> 3.0918245914020837 r_1833 hexacosanoyl-CoA transport hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_1833_REV hexacosanoyl-CoA transport (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_1834 hexadecanal exchange hexadecanal --> 0.0 @@ -2133,7 +2133,7 @@ r_1838_EXP_2 homocitrate synthase 10.507993633138625 prot_P48570 + 2-oxoglutarat r_1839 hydrogen peroxide transport hydrogen peroxide --> hydrogen peroxide 0.0 r_1839_REV hydrogen peroxide transport (reversible) hydrogen peroxide --> hydrogen peroxide 0.0 r_1840 hydroxymethylglutaryl-CoA transport 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.0 -r_1840_REV hydroxymethylglutaryl-CoA transport (reversible) 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.06416760246059944 +r_1840_REV hydroxymethylglutaryl-CoA transport (reversible) 3-hydroxy-3-methylglutaryl-CoA --> 3-hydroxy-3-methylglutaryl-CoA 0.06416760246059945 r_1841 hypoxanthine exchange hypoxanthine --> 0.0 r_1842 hypoxanthine transport hypoxanthine --> hypoxanthine 0.0 r_1842_REV hypoxanthine transport (reversible) hypoxanthine --> hypoxanthine 0.0 @@ -2182,7 +2182,7 @@ r_1868 isobutyl alcohol transport isobutanol --> isobutanol 0.0 r_1868_REV isobutyl alcohol transport (reversible) isobutanol --> isobutanol 0.0 r_1869 isobutyl alcohol transport isobutanol --> isobutanol 0.0 r_1869_REV isobutyl alcohol transport (reversible) isobutanol --> isobutanol 0.0 -r_1870 isobutyraldehyde exchange isobutyraldehyde --> -1.2006506899808755e-12 +r_1870 isobutyraldehyde exchange isobutyraldehyde --> 0.0 r_1871 L-1-pyrroline-3-hydroxy-5-carboxylate spontaneous conversion to L-4-hydroxyglutamate semialdehyde 0.31953703703703706 prot_standard + 1-pyrroline-3-hydroxy-5-carboxylic acid + H+ + H2O --> L-4-hydroxyglutamic semialdehyde 0.0 r_1872 L-2-amino-3-oxobutanoate decarboxylation (spontaneous) 0.062476381011109826 prot_standard + H+ + L-2-amino-3-oxobutanoate --> aminoacetone + carbon dioxide 0.0 r_1873 L-alanine exchange L-alanine --> 0.0 @@ -2342,9 +2342,9 @@ r_1975 nucleoside-triphosphatase (dGTP) 0.5934259259259259 prot_standard + dGTP r_1976 O-acetylcarnintine transport into mitochondria 1.094665810308139 prot_Q12289 + O-acetylcarnitine --> O-acetylcarnitine 0.0 r_1977 O2 transport oxygen --> oxygen 0.010694455410100273 r_1977_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1978 O2 transport oxygen --> oxygen 8.004936995018783 +r_1978 O2 transport oxygen --> oxygen 7.411727915285416 r_1978_REV O2 transport (reversible) oxygen --> oxygen 0.0 -r_1979 O2 transport oxygen --> oxygen 8.166724890621373 +r_1979 O2 transport oxygen --> oxygen 7.573515810887891 r_1979_REV O2 transport (reversible) oxygen --> oxygen 0.0 r_1980 O2 transport oxygen --> oxygen 0.0 r_1980_REV O2 transport (reversible) oxygen --> oxygen 0.0 @@ -2352,31 +2352,31 @@ r_1981 octadecanoate (n-C18:0) transport 0.6366271866276696 prot_P38225 + steara r_1981_REV octadecanoate (n-C18:0) transport (reversible) 0.6366271866276696 prot_P38225 + stearate --> stearate 0.0 r_1984 octanoate exchange octanoate --> 0.0 r_1987 ornithine exchange ornithine --> 0.0 -r_1988 oxaloacetate transport oxaloacetate --> oxaloacetate 0.5810700443165501 +r_1988 oxaloacetate transport oxaloacetate --> oxaloacetate 0.3467745288594432 r_1988_REV oxaloacetate transport (reversible) oxaloacetate --> oxaloacetate 0.0 -r_1989 oxaloacetate(2-) exchange oxaloacetate --> 0.5810700443165501 +r_1989 oxaloacetate(2-) exchange oxaloacetate --> 0.3467745288594432 r_1990 oxidized glutathione uniport 6.850627360229916 prot_P40897 + glutathione disulfide --> glutathione disulfide 0.0 r_1991 oxidized thioredoxin transport TRX1 disulphide --> TRX1 disulphide 0.0 r_1991_REV oxidized thioredoxin transport (reversible) TRX1 disulphide --> TRX1 disulphide 0.0 -r_1992 oxygen exchange oxygen <-- -8.166724890621373 +r_1992 oxygen exchange oxygen <-- -7.573515810887891 r_1993 palmitate exchange palmitate --> 0.0 r_1994 palmitoleate exchange palmitoleate --> 0.0 r_1995 palmitoyl-CoA transport palmitoyl-CoA --> palmitoyl-CoA 0.0 r_1995_REV palmitoyl-CoA transport (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 -r_1996 panthetheine 4'-phosphate transport pantetheine 4'-phosphate --> pantetheine 4'-phosphate 0.0 +r_1996 panthetheine 4'-phosphate transport pantetheine 4'-phosphate --> pantetheine 4'-phosphate 5.5100001772612206e-05 r_1996_REV panthetheine 4'-phosphate transport (reversible) pantetheine 4'-phosphate --> pantetheine 4'-phosphate 0.0 -r_1997 panthetheine-phosphate adenylyltransferase 3.214741247115812 prot_standard + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 0.0 +r_1997 panthetheine-phosphate adenylyltransferase 3.214741247115812 prot_standard + ATP + H+ + pantetheine 4'-phosphate --> 3'-dephospho-CoA + diphosphate 0.0004977833232718831 r_1998 PAP uniport adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0 r_1998_REV PAP uniport (reversible) adenosine 3',5'-bismonophosphate --> adenosine 3',5'-bismonophosphate 0.0 r_1999 pectin exchange pectin --> 0.0 r_2000 phenethyl acetate exchange phenethyl acetate --> 0.0 r_2001 phenylacetaldehyde exchange phenylacetaldehyde --> 0.0 -r_2002 phenylacetaldehyde transport phenylacetaldehyde --> phenylacetaldehyde 0.0 -r_2002_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phenylacetaldehyde 0.0 +r_2002 phenylacetaldehyde transport phenylacetaldehyde --> phenylacetaldehyde 1000.0 +r_2002_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phenylacetaldehyde 1000.0 r_2003 phenylacetaldehyde transport phenylacetaldehyde --> phenylacetaldehyde 0.0 r_2003_REV phenylacetaldehyde transport (reversible) phenylacetaldehyde --> phenylacetaldehyde 0.0 r_2004 phenylalanine transport L-phenylalanine --> L-phenylalanine 0.0 -r_2005 phosphate exchange phosphate <=> -0.08106295972630928 +r_2005 phosphate exchange phosphate <=> -0.08106295972626476 r_2008 phosphate transport 2.5123737373737374 prot_P27514 + phosphate --> phosphate 0.0 r_2008_REV phosphate transport (reversible) 2.5123737373737374 prot_P27514 + phosphate --> phosphate 0.0 r_2020 potassium exchange potassium <=> -0.0010526999807916584 @@ -2390,10 +2390,10 @@ r_2026 pyridoxamine kinase 0.07735564304461942 prot_P53727 + ATP + pyridoxamine r_2027 pyridoxamine phosphatase 11.27565182849182 prot_standard + H2O + pyridoxamine 5'-phosphate --> phosphate + pyridoxamine 0.0 r_2028 pyridoxine exchange pyridoxine --> 0.0 r_2029 pyridoxine kinase 0.08096311475409836 prot_P39988 + ATP + pyridoxine --> ADP + H+ + pyridoxine 5'-phosphate 0.0 -r_2030 pyrimidine phosphatase 3.5775737902860114 prot_standard + 5-amino-6-(5-phosphoribitylamino)uracil + H2O --> 5-amino-6-(D-ribitylamino)uracil + phosphate 0.00028999999161897003 +r_2030 pyrimidine phosphatase 3.5775737902860114 prot_standard + 5-amino-6-(5-phosphoribitylamino)uracil + H2O --> 5-amino-6-(D-ribitylamino)uracil + phosphate 0.00028999999162475826 r_2031 pyrimidine-nucleoside phosphorylase (uracil) 0.9660422049956934 prot_standard + phosphate + uridine --> alpha-D-ribose 1-phosphate(2-) + uracil 0.0 r_2031_REV pyrimidine-nucleoside phosphorylase (uracil) (reversible) 0.9660422049956934 prot_standard + alpha-D-ribose 1-phosphate(2-) + uracil --> phosphate + uridine 0.0 -r_2032 pyrophosphate transport diphosphate --> diphosphate 0.07978846592456523 +r_2032 pyrophosphate transport diphosphate --> diphosphate 0.07928778260135057 r_2032_REV pyrophosphate transport (reversible) diphosphate --> diphosphate 0.0 r_2033 pyruvate exchange pyruvate --> 0.0 r_2034_EXP_1 pyruvate transport 0.010426331697901588 prot_P53157 + 0.011285052581323294 prot_P53311 + H+ + pyruvate --> H+ + pyruvate 0.0 @@ -2403,7 +2403,7 @@ r_2036_REV quinolinate transport (reversible) quinolinate --> quinolinate 0.0 r_2037 reduced thioredoxin transport TRX1 --> TRX1 0.0 r_2037_REV reduced thioredoxin transport (reversible) TRX1 --> TRX1 0.0 r_2038 riboflavin exchange riboflavin --> 0.0 -r_2039 riboflavin transport riboflavin --> riboflavin 0.0 +r_2039 riboflavin transport riboflavin --> riboflavin 2.8999999267398372e-06 r_2040 riboflavin transport 71.18089610319483 prot_Q08777 + riboflavin --> riboflavin 0.0 r_2041_EXP_1 ribose transporter 11.163122614359402 prot_P39004 + D-ribose --> D-ribose 0.0 r_2041_EXP_2 ribose transporter 10.784451386239029 prot_P32467 + D-ribose --> D-ribose 0.0 @@ -2411,7 +2411,7 @@ r_2042 S-adenosyl-L-homocysteine transport S-adenosyl-L-homocysteine --> S-adeno r_2042_REV S-adenosyl-L-homocysteine transport (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.0 r_2043 S-adenosyl-L-methionine exchange S-adenosyl-L-methionine --> 0.0 r_2044 S-methyl-L-methionine exchange S-methyl-L-methionine --> 0.0 -r_2045 serine transport 7.412955094957308 prot_P48813 + L-serine --> L-serine 5.5100001773222835e-05 +r_2045 serine transport 7.412955094957308 prot_P48813 + L-serine --> L-serine 5.510000177261221e-05 r_2045_REV serine transport (reversible) 7.412955094957308 prot_P48813 + L-serine --> L-serine 0.0 r_2046 sn-glycero-3-phosphocholine exchange sn-glycero-3-phosphocholine --> 0.0 r_2049 sodium exchange sodium <=> -0.0011512999888509499 @@ -2427,7 +2427,7 @@ r_2056 succinate exchange succinate --> 0.0 r_2057 succinate transport succinate --> succinate 0.0 r_2057_REV succinate transport (reversible) succinate --> succinate 0.0 r_2058 sucrose exchange sucrose --> 0.0 -r_2060 sulphate exchange sulphate <=> -0.04038225804972491 +r_2060 sulphate exchange sulphate <=> -0.0403822580497243 r_2061 sulphite exchange sulphite --> 0.0 r_2062 taurine exchange taurine --> 0.0 r_2063 tetracosanoyl-CoA transport tetracosanoyl-CoA --> tetracosanoyl-CoA 0.0 @@ -2455,13 +2455,13 @@ r_2085_REV tryptophol transport (reversible) tryptophol --> tryptophol 0.0 r_2086 tyrosine transport L-tyrosine --> L-tyrosine 0.0 r_2087 tyrosine transport L-tyrosine --> L-tyrosine 0.0 r_2087_REV tyrosine transport (reversible) L-tyrosine --> L-tyrosine 0.0 -r_2089 UMP transport UMP --> UMP 0.014290109378625914 +r_2089 UMP transport UMP --> UMP 0.0 r_2089_REV UMP transport (reversible) UMP --> UMP 0.0 r_2090 uracil exchange uracil --> 0.0 r_2091 urea exchange urea --> 0.0 r_2092 uridine exchange uridine --> 0.0 r_2093 valine transport L-valine --> L-valine 0.0 -r_2093_REV valine transport (reversible) L-valine --> L-valine 0.1963670746775834 +r_2093_REV valine transport (reversible) L-valine --> L-valine 0.19636707467878406 r_2094_EXP_1 water diffusion 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_2094_EXP_2 water diffusion 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_2094_REV_EXP_1 water diffusion (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.010694455410100273 @@ -2469,14 +2469,14 @@ r_2094_REV_EXP_2 water diffusion (reversible) 0.8260858585858586 prot_P0CD91 + H r_2095 water diffusion H2O --> H2O 0.0 r_2095_REV water diffusion (reversible) H2O --> H2O 0.0 r_2096 water diffusion H2O --> H2O 0.0 -r_2096_REV water diffusion (reversible) H2O --> H2O 19.345145413745563 +r_2096_REV water diffusion (reversible) H2O --> H2O 18.654373069620885 r_2097 water diffusion H2O --> H2O 0.0 r_2097_REV water diffusion (reversible) H2O --> H2O 0.0 -r_2098 water diffusion H2O --> H2O 0.0 +r_2098 water diffusion H2O --> H2O 3.922891305596643e-05 r_2098_REV water diffusion (reversible) H2O --> H2O 0.0 r_2099 water diffusion H2O --> H2O 0.0 r_2099_REV water diffusion (reversible) H2O --> H2O 0.0 -r_2100 water exchange H2O <=> 13.997537829919185 +r_2100 water exchange H2O <=> 13.518999487189447 r_2101 xanthine transport 9H-xanthine --> 9H-xanthine 0.0 r_2101_REV xanthine transport (reversible) 9H-xanthine --> 9H-xanthine 0.0 r_2102 xanthosine exchange xanthosine --> 0.0 @@ -2496,20 +2496,20 @@ r_2111 growth biomass --> 0.29 r_2112 kynurenine aminotransferase 0.06921227197346601 prot_P47039 + L-kynurenine + pyruvate --> H2O + L-alanine + kynurenic acid 0.0 r_2112_REV kynurenine aminotransferase (reversible) 0.009033549783549784 prot_P47039 + H2O + L-alanine + kynurenic acid --> L-kynurenine + pyruvate 0.0 r_2113 spontaneous kynurenic acid to quinaldic acid 0.41264716703458426 prot_standard + 2.0 H+ + NADPH + kynurenic acid --> H2O + NADP(+) + quinaldic acid 0.0 -r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.41264716703458426 prot_standard + 2-amino-3-carboxymuconate-6-semialdehyde --> H+ + H2O + quinolinate 0.0017602999924600823 +r_2114 spontaneous 2-amino-3-carboxymuconate-6-semialdehyde to quinolinate 0.41264716703458426 prot_standard + 2-amino-3-carboxymuconate-6-semialdehyde --> H+ + H2O + quinolinate 0.0017602999924575258 r_2115_EXP_1 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.03339649287148808 prot_P38113 + acetaldehyde + H+ + NADH --> ethanol + NAD 0.0 -r_2115_EXP_2 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.011373148148148148 prot_P00330 + acetaldehyde + H+ + NADH --> ethanol + NAD 3.395928738294883 +r_2115_EXP_2 alcohol dehydrogenase, (acetaldehyde to ethanol) 0.011373148148148148 prot_P00330 + acetaldehyde + H+ + NADH --> ethanol + NAD 3.784862050583791 r_2116_EXP_1 acetaldehyde dehydrogenase 0.06942013888888889 prot_Q04458 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_2 acetaldehyde dehydrogenase 0.483596214511041 prot_P47771 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_3 acetaldehyde dehydrogenase 20.997407407407408 prot_P40047 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 r_2116_EXP_4 acetaldehyde dehydrogenase 0.43890436397400184 prot_P46367 + acetaldehyde + H2O + NAD --> acetate + 2.0 H+ + NADH 0.0 -r_2117 phenylalanine transaminase 0.05744797801334904 prot_P38840 + L-phenylalanine + pyruvate --> keto-phenylpyruvate + L-alanine 0.13463130909849935 +r_2117 phenylalanine transaminase 0.05744797801334904 prot_P38840 + L-phenylalanine + pyruvate --> keto-phenylpyruvate + L-alanine 0.1346313090984988 r_2117_REV phenylalanine transaminase (reversible) 0.010556998556998556 prot_P38840 + keto-phenylpyruvate + L-alanine --> L-phenylalanine + pyruvate 0.0 r_2118 tryptophan transaminase 0.05744797801334904 prot_P38840 + keto-phenylpyruvate + L-tryptophan --> indole-3-pyruvate + L-phenylalanine 0.0 r_2119 tyrosine transaminase 0.010556998556998556 prot_P38840 + 3-(4-hydroxyphenyl)pyruvate + L-alanine --> L-tyrosine + pyruvate 0.03567744162992795 r_2119_REV tyrosine transaminase (reversible) 0.11696243005595523 prot_P38840 + L-tyrosine + pyruvate --> 3-(4-hydroxyphenyl)pyruvate + L-alanine 0.0 r_2125 coenzyme A: cytoplasm to LP coenzyme A --> coenzyme A 0.0 -r_2125_REV coenzyme A: cytoplasm to LP (reversible) coenzyme A --> coenzyme A 0.003112604653940862 +r_2125_REV coenzyme A: cytoplasm to LP (reversible) coenzyme A --> coenzyme A 0.004029785700138254 r_2126 sedoheptulose bisphosphatase 2.051719576719577 prot_P36136 + H2O + sedoheptulose 1,7-bisphosphate --> phosphate + sedoheptulose 7-phosphate 0.0 r_2129 proton leak H+ --> H+ 0.0 r_2131 isocitrate dehydrogenase 0.47807539682539685 prot_P21954 + isocitrate + NADP(+) --> 2-oxoglutarate + carbon dioxide + NADPH 0.0 @@ -2521,8 +2521,8 @@ r_2136_REV 14-demethyllanosterol transport (reversible) 14-demethyllanosterol -- r_2137 ergosta-5,7,22,24(28)-tetraen-3beta-ol exchange ergosta-5,7,22,24(28)-tetraen-3beta-ol --> 0.0 r_2139 ergosta-5,7,22,24(28)-tetraen-3beta-ol transport ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 r_2139_REV ergosta-5,7,22,24(28)-tetraen-3beta-ol transport (reversible) ergosta-5,7,22,24(28)-tetraen-3beta-ol --> ergosta-5,7,22,24(28)-tetraen-3beta-ol 0.0 -r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 27.714912457481013 prot_P07149 + 25.079771343596047 prot_P19097 + acetyl-CoA + 21.0 H+ + 7.0 malonyl-CoA + 14.0 NADPH --> 7.0 carbon dioxide + 7.0 coenzyme A + 7.0 H2O + 14.0 NADP(+) + palmitoyl-CoA 0.03996705668514179 -r_2141 fatty-acyl-CoA synthase (n-C18:0CoA) 50.82022222222222 prot_P07149 + 45.98822222222222 prot_P19097 + acetyl-CoA + 24.0 H+ + 8.0 malonyl-CoA + 16.0 NADPH --> 8.0 carbon dioxide + 8.0 coenzyme A + 8.0 H2O + 16.0 NADP(+) + stearoyl-CoA 0.007476038061993512 +r_2140 fatty-acyl-CoA synthase (n-C16:0CoA) 27.714912457481013 prot_P07149 + 25.079771343596047 prot_P19097 + acetyl-CoA + 21.0 H+ + 7.0 malonyl-CoA + 14.0 NADPH --> 7.0 carbon dioxide + 7.0 coenzyme A + 7.0 H2O + 14.0 NADP(+) + palmitoyl-CoA 0.0399670566851418 +r_2141 fatty-acyl-CoA synthase (n-C18:0CoA) 50.82022222222222 prot_P07149 + 45.98822222222222 prot_P19097 + acetyl-CoA + 24.0 H+ + 8.0 malonyl-CoA + 16.0 NADPH --> 8.0 carbon dioxide + 8.0 coenzyme A + 8.0 H2O + 16.0 NADP(+) + stearoyl-CoA 0.007476038061993509 r_2142 B-ketoacyl-ACP synthase (acetoacetyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + acetyl-ACP + carboxyacetyl-ACP --> carbon dioxide + ACP1 + acetoacetyl-ACP 0.0 r_2143 B-ketoacyl-ACP synthase (3-oxo-hexanoyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + carboxyacetyl-ACP + butanoyl-ACP --> carbon dioxide + ACP1 + 3-oxo-hexanoyl-ACP 0.0 r_2144 B-ketoacyl-ACP synthase (3-oxo-octanoyl-ACP) 0.007029138939302279 prot_P32463 + 0.023974087517644686 prot_P39525 + carboxyacetyl-ACP + hexanoyl-ACP --> carbon dioxide + ACP1 + 3-oxo-octanoyl-ACP 0.0 @@ -2575,8 +2575,8 @@ r_2178 trans-2-enoyl-CoA reductase (n-C20:0CoA) 102.13333333333334 prot_Q99190 + r_2179 trans-2-enoyl-CoA reductase (n-C22:0CoA) 3.5110799393544463 prot_Q99190 + H+ + NADPH + trans-docos-2-enoyl-CoA --> docosanoyl-CoA + NADP(+) 0.0 r_2180 trans-2-enoyl-CoA reductase (n-C24:0CoA) 102.13333333333334 prot_Q99190 + H+ + NADPH + trans-tetracos-2-enoyl-CoA --> tetracosanoyl-CoA + NADP(+) 0.0 r_2181 trans-2-enoyl-CoA reductase (n-C26:0CoA) 3.3101254736377603 prot_Q99190 + H+ + NADPH + trans-hexacos-2-enoyl-CoA --> NADP(+) + hexacosanoyl-CoA 0.0 -r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 13.846040131031963 prot_P21147 + H+ + palmitoyl-CoA + oxygen + NADH --> 2.0 H2O + palmitoleoyl-CoA(4-) + NAD 0.027049563655187424 -r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 46.3515873015873 prot_P21147 + H+ + stearoyl-CoA + oxygen + NADH --> 2.0 H2O + NAD + oleoyl-CoA 0.00893884006371369 +r_2182 palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA), ER membrane 13.846040131031963 prot_P21147 + H+ + palmitoyl-CoA + oxygen + NADH --> 2.0 H2O + palmitoleoyl-CoA(4-) + NAD 0.02704956365518743 +r_2183 stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA), ER membrane 46.3515873015873 prot_P21147 + H+ + stearoyl-CoA + oxygen + NADH --> 2.0 H2O + NAD + oleoyl-CoA 0.008938840063713687 r_2184 octanoate (n-C8:0) transport octanoate --> octanoate 0.0 r_2184_REV octanoate (n-C8:0) transport (reversible) octanoate --> octanoate 0.0 r_2185 decanoate (n-C10:0) transport decanoate --> decanoate 0.0 @@ -2752,14 +2752,14 @@ r_2301 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-dodecadienoyl- r_2302 delta(3,5)-delta(2,4)-dienoyl-CoA isomerase (trans-3,cis-5-tetradecadienoyl-CoA) 0.0026092013888888888 prot_Q08558 + trans-3,cis-5-tetradecadienoyl-CoA --> trans-2,trans-4-tetradecadienoyl-CoA 0.0 r_2303 2,4-dienoyl-CoA reductase (trans-2,trans-4-dodecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-dodecadienoyl-CoA --> NADP(+) + trans-dodec-3-enoyl-CoA 0.0 r_2304 2,4-dienoyl-CoA reductase (trans-2,trans-4-tetradecadienoyl-CoA) 4.197905702642161 prot_P32573 + H+ + NADPH + trans-2,trans-4-tetradecadienoyl-CoA --> NADP(+) + trans-tetradec-3-enoyl-CoA 0.0 -r_2305 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 2.50194742075915 +r_2305 cis-aconitate(3-) to isocitrate 0.16582750582750583 prot_P19414 + cis-aconitate + H2O --> isocitrate 2.2948399936839543 r_2305_REV cis-aconitate(3-) to isocitrate (reversible) 0.16582750582750583 prot_P19414 + isocitrate --> cis-aconitate + H2O 0.0 r_2308_EXP_1 glycerol-3-phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.00914442129407482 r_2308_EXP_2 glycerol-3-phosphate acyltransferase (16:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + palmitoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0 -r_2309_EXP_1 glycerol-3-phosphate acyltransferase (16:1), ER membrane 124.56838874829987 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.010219940177067878 +r_2309_EXP_1 glycerol-3-phosphate acyltransferase (16:1), ER membrane 124.56838874829987 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.01021994017706962 r_2309_EXP_2 glycerol-3-phosphate acyltransferase (16:1), ER membrane 121.5898765007065 prot_P36148 + 2.0 H+ + palmitoleoyl-CoA(4-) + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0 r_2310 glycerol-3-phosphate acyltransferase (18:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + stearoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0 -r_2311 glycerol-3-phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 2.663179865653592e-06 +r_2311 glycerol-3-phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + glycerol 3-phosphate --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 2.6631798656358383e-06 r_2312_EXP_1 dihydroxyacetone phosphate acyltransferase (16:0), ER membrane 100.01633986928105 prot_P32784 + 2.0 H+ + palmitoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (16:0) 0.0 r_2312_EXP_2 dihydroxyacetone phosphate acyltransferase (16:0), ER membrane 97.624883286648 prot_P36148 + 2.0 H+ + palmitoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (16:0) 0.0 r_2313_EXP_1 dihydroxyacetone phosphate acyltransferase (16:1), ER membrane 165.43182491128994 prot_P32784 + 2.0 H+ + palmitoleoyl-CoA(4-) + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (16:1) 0.0 @@ -2768,7 +2768,7 @@ r_2314 dihydroxyacetone phosphate acyltransferase (18:0), ER membrane 97.6248832 r_2315 dihydroxyacetone phosphate acyltransferase (18:1), ER membrane 106.58129459734965 prot_P36148 + 2.0 H+ + oleoyl-CoA + dihydroxyacetone phosphate --> coenzyme A + acylglycerone phosphate (18:1) 0.0 r_2316 glycerol-3-phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:0) 0.0 r_2317 glycerol-3-phosphate acyltransferase (16:1), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + palmitoleoyl-CoA(4-) --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (16:1) 0.0 -r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + stearoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0008023349197814906 +r_2318 glycerol-3-phosphate acyltransferase (18:0), lipid particle 97.624883286648 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + stearoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:0) 0.0008023349197814968 r_2319 glycerol-3-phosphate acyltransferase (18:1), lipid particle 106.58129459734965 prot_P36148 + glycerol 3-phosphate + 2.0 H+ + oleoyl-CoA --> coenzyme A + 1-acyl-sn-glycerol 3-phosphate (18:1) 0.0 r_2320 dihydroxyacetone phosphate acyltransferase (16:0), lipid particle 97.624883286648 prot_P36148 + dihydroxyacetone phosphate + 2.0 H+ + palmitoyl-CoA --> coenzyme A + acylglycerone phosphate (16:0) 0.0 r_2321 dihydroxyacetone phosphate acyltransferase (16:1), lipid particle 97.624883286648 prot_P36148 + dihydroxyacetone phosphate + 2.0 H+ + palmitoleoyl-CoA(4-) --> coenzyme A + acylglycerone phosphate (16:1) 0.0 @@ -2782,16 +2782,16 @@ r_2328 acyl dhap reductase (16:0), lipid particle 0.09115 prot_P40471 + H+ + acy r_2329 acyl dhap reductase (16:1), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (16:1) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (16:1) + NADP(+) 0.0 r_2330 acyl dhap reductase (18:0), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (18:0) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (18:0) + NADP(+) 0.0 r_2331 acyl dhap reductase (18:1), lipid particle 0.09115 prot_P40471 + H+ + acylglycerone phosphate (18:1) + NADPH --> 1-acyl-sn-glycerol 3-phosphate (18:1) + NADP(+) 0.0 -r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-16:1) 0.006512052340516224 +r_2332 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-16:1) 0.006512052340513822 r_2333_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0 -r_2333_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.002632368953560327 -r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 113.27321041547852 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-16:1) 0.007703881504606214 +r_2333_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0026323689535609975 +r_2334 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-16:1), ER membrane 113.27321041547852 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-16:1) 0.007703881504608617 r_2335_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 -r_2335_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0025160586724616647 +r_2335_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0025160586724610016 r_2336 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-16:1) 0.0 r_2337_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 r_2337_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), ER membrane 43.08868501529052 prot_Q06508 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 -r_2338 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-16:1) 2.663179865653592e-06 +r_2338 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-16:1), ER membrane 84.29971988795519 prot_Q08548 + palmitoleoyl-CoA(4-) + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-16:1) 2.663179865636245e-06 r_2339_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), ER membrane 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2339_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), ER membrane 92.0336391437309 prot_Q08548 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2340_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:0) --> coenzyme A + phosphatidate (1-16:0, 2-18:1) 0.0 @@ -2802,7 +2802,7 @@ r_2341_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), li r_2341_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (16:1) --> coenzyme A + phosphatidate (1-16:1, 2-18:1) 0.0 r_2342_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 r_2342_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0 -r_2342_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0008023349197814907 +r_2342_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:0) --> coenzyme A + phosphatidate (1-18:0, 2-18:1) 0.0008023349197814968 r_2343_EXP_1 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 43.17915392456677 prot_P33333 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2343_EXP_2 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 4.0567025820913845 prot_P36165 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 r_2343_EXP_3 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle 2.869687642509904 prot_Q12043 + oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate (18:1) --> coenzyme A + phosphatidate (1-18:1, 2-18:1) 0.0 @@ -2822,12 +2822,12 @@ r_2356 PA phosphatase (1-18:0, 2-16:1), vacuolar membrane 0.0963012769674609 pro r_2357 PA phosphatase (1-18:0, 2-18:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0 r_2358 PA phosphatase (1-18:1, 2-16:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:1, 2-16:1) --> phosphate + diglyceride (1-18:1, 2-16:1) + 2.0 H+ 0.0 r_2359 PA phosphatase (1-18:1, 2-18:1), vacuolar membrane 0.0963012769674609 prot_Q05521 + H2O + phosphatidate (1-18:1, 2-18:1) --> phosphate + diglyceride (1-18:1, 2-18:1) + 2.0 H+ 0.0 -r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + phosphatidate (1-16:0, 2-16:1) + H2O --> phosphate + diglyceride (1-16:0, 2-16:1) + 2.0 H+ 0.006512052340513823 -r_2361 PA phosphatase (1-16:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:0, 2-18:1) --> phosphate + diglyceride (1-16:0, 2-18:1) + 2.0 H+ 0.0002383540915949086 +r_2360 PA phosphatase (1-16:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + phosphatidate (1-16:0, 2-16:1) + H2O --> phosphate + diglyceride (1-16:0, 2-16:1) + 2.0 H+ 0.006512052340514181 +r_2361 PA phosphatase (1-16:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:0, 2-18:1) --> phosphate + diglyceride (1-16:0, 2-18:1) + 2.0 H+ 0.00023835409159523194 r_2362 PA phosphatase (1-16:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-16:1) --> phosphate + diglyceride (1-16:1, 2-16:1) + 2.0 H+ 0.0024251158605752597 -r_2363 PA phosphatase (1-16:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-18:1) --> phosphate + diglyceride (1-16:1, 2-18:1) + 2.0 H+ 0.0025160586724616647 +r_2363 PA phosphatase (1-16:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-16:1, 2-18:1) --> phosphate + diglyceride (1-16:1, 2-18:1) + 2.0 H+ 0.0025160586724610016 r_2364 PA phosphatase (1-18:0, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-16:1) --> phosphate + diglyceride (1-18:0, 2-16:1) + 2.0 H+ 0.0 -r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0008023349197814907 +r_2365 PA phosphatase (1-18:0, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:0, 2-18:1) --> phosphate + diglyceride (1-18:0, 2-18:1) + 2.0 H+ 0.0008023349197814968 r_2366 PA phosphatase (1-18:1, 2-16:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:1, 2-16:1) --> phosphate + diglyceride (1-18:1, 2-16:1) + 2.0 H+ 0.0 r_2367 PA phosphatase (1-18:1, 2-18:1), Golgi membrane 0.09076123811822581 prot_Q04396 + H2O + phosphatidate (1-18:1, 2-18:1) --> phosphate + diglyceride (1-18:1, 2-18:1) + 2.0 H+ 0.0 r_2368_EXP_1 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:0), ER membrane 67.08130559354814 prot_P25628 + palmitoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-16:0) 0.0 @@ -2862,7 +2862,7 @@ r_2377_EXP_2 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membran r_2377_EXP_3 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 r_2378_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_2378_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 -r_2378_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0009171810461973792 +r_2378_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 r_2379_EXP_1 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 65.49132949141813 prot_P25628 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2379_EXP_2 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 21.58307405873162 prot_P53629 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2379_EXP_3 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 @@ -2936,7 +2936,7 @@ r_2406 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:0), lipid particle 1 r_2407 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:0), lipid particle 14.405495169082126 prot_Q08650 + palmitoyl-CoA + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-16:0) 0.0 r_2408 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-16:1) 0.0 r_2409 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-16:1) 0.0 -r_2410 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 +r_2410 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-16:1) 0.000917181046197385 r_2411 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-16:1) 0.0 r_2412 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-18:0, 2-16:1) --> coenzyme A + triglyceride (1-18:0, 2-16:1, 3-16:1) 0.0 r_2413 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-18:0, 2-18:1) --> coenzyme A + triglyceride (1-18:0, 2-18:1, 3-16:1) 0.0 @@ -2944,7 +2944,7 @@ r_2414 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:1), lipid particle 1 r_2415 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:1), lipid particle 14.405495169082126 prot_Q08650 + palmitoleoyl-CoA(4-) + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-16:1) 0.0 r_2416 diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-16:1) --> coenzyme A + triglyceride (1-16:0, 2-16:1, 3-18:0) 0.0 r_2417 diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:0, 2-18:1) --> coenzyme A + triglyceride (1-16:0, 2-18:1, 3-18:0) 0.0 -r_2418 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0015079348143778807 +r_2418 diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-16:1) --> coenzyme A + triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0015079348143778749 r_2419 diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-16:1, 2-18:1) --> coenzyme A + triglyceride (1-16:1, 2-18:1, 3-18:0) 0.0 r_2420 diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-18:0, 2-16:1) --> coenzyme A + triglyceride (1-18:0, 2-16:1, 3-18:0) 0.0 r_2421 diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:0), lipid particle 14.405495169082126 prot_Q08650 + stearoyl-CoA + diglyceride (1-18:0, 2-18:1) --> coenzyme A + triglyceride (1-18:0, 2-18:1, 3-18:0) 0.0 @@ -2960,13 +2960,13 @@ r_2430 diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:1), lipid particle 1 r_2431 diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:1), lipid particle 14.405495169082126 prot_Q08650 + oleoyl-CoA + diglyceride (1-18:1, 2-18:1) --> coenzyme A + triglyceride (1-18:1, 2-18:1, 3-18:1) 0.0 r_2432 CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) 0.0 r_2432_REV CDP-diacylglycerol synthase (1-16:0, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-16:1) --> H+ + phosphatidate (1-16:0, 2-16:1) + CTP 0.0 -r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.005278765644030954 +r_2433 CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) 0.005278765644033357 r_2433_REV CDP-diacylglycerol synthase (1-16:1, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:1, 2-16:1) --> H+ + phosphatidate (1-16:1, 2-16:1) + CTP 0.0 r_2434 CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:0, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) 0.0 r_2434_REV CDP-diacylglycerol synthase (1-18:0, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:0, 2-16:1) --> H+ + phosphatidate (1-18:0, 2-16:1) + CTP 0.0 -r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.01007146320421754 +r_2435 CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-18:1, 2-16:1) + CTP --> diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) 0.010071463204217536 r_2435_REV CDP-diacylglycerol synthase (1-18:1, 2-16:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-18:1, 2-16:1) --> H+ + phosphatidate (1-18:1, 2-16:1) + CTP 0.0 -r_2436 CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0023940148619654186 +r_2436 CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:0, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) 0.0023940148619657656 r_2436_REV CDP-diacylglycerol synthase (1-16:0, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:0, 2-18:1) --> H+ + phosphatidate (1-16:0, 2-18:1) + CTP 0.0 r_2437 CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane 1.6138203786746388 prot_P38221 + H+ + phosphatidate (1-16:1, 2-18:1) + CTP --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 0.0 r_2437_REV CDP-diacylglycerol synthase (1-16:1, 2-18:1), ER membrane (reversible) 1.6138203786746388 prot_P38221 + diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) --> H+ + phosphatidate (1-16:1, 2-18:1) + CTP 0.0 @@ -2987,9 +2987,9 @@ r_2444_REV CDP-diacylglycerol synthase (1-16:0, 2-18:1), mitochondrial membrane r_2445 CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane 1.3764324862979571 prot_P53230 + CTP + H+ + phosphatidate (1-16:1, 2-18:1) --> diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) 0.0 r_2445_REV CDP-diacylglycerol synthase (1-16:1, 2-18:1), mitochondrial membrane (reversible) 1.3764324862979571 prot_P53230 + diphosphate + CDP-diacylglycerol (1-16:1, 2-18:1) --> CTP + H+ + phosphatidate (1-16:1, 2-18:1) 0.0 r_2446 PS synthase (1-16:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-16:1) 0.0 -r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-16:1) 0.005278765644030954 +r_2447 PS synthase (1-16:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-16:1) 0.005278765644033357 r_2448 PS synthase (1-18:0, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-16:1) 0.01007146320421754 +r_2449 PS synthase (1-18:1, 2-16:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:1, 2-16:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:1, 2-16:1) 0.010071463204217536 r_2450 PS synthase (1-16:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 r_2451 PS synthase (1-16:1, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-16:1, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-16:1, 2-18:1) 0.0 r_2452 PS synthase (1-18:0, 2-18:1), ER membrane 13.743901586999591 prot_P08456 + CDP-diacylglycerol (1-18:0, 2-18:1) + L-serine --> 2.0 H+ + CMP + phosphatidyl-L-serine (1-18:0, 2-18:1) 0.0 @@ -2998,7 +2998,7 @@ r_2454 PI synthase (1-16:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 r_2455 PI synthase (1-16:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) 0.0 r_2456 PI synthase (1-18:0, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:0, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) 0.0 r_2457 PI synthase (1-18:1, 2-16:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:1, 2-16:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 -r_2458 PI synthase (1-16:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0023940148619654186 +r_2458 PI synthase (1-16:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0023940148619657656 r_2459 PI synthase (1-16:1, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-16:1, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 0.0 r_2460 PI synthase (1-18:0, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:0, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) 0.0 r_2461 PI synthase (1-18:1, 2-18:1), ER membrane 1.0528713873939686 prot_P06197 + CDP-diacylglycerol (1-18:1, 2-18:1) + myo-inositol --> 2.0 H+ + CMP + 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) 0.0 @@ -3025,7 +3025,7 @@ r_2479 PS decarboxylase (1-18:1, 2-18:1), Golgi membrane 0.09853409090909093 pro r_2480 PS decarboxylase (1-16:0, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-16:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-16:1) 0.0 r_2481 PS decarboxylase (1-16:1, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-16:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-16:1) 0.0 r_2482 PS decarboxylase (1-18:0, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-18:0, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_2483 PS decarboxylase (1-18:1, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.0029287186135979392 +r_2483 PS decarboxylase (1-18:1, 2-16:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-18:1, 2-16:1) --> carbon dioxide + phosphatidylethanolamine (1-18:1, 2-16:1) 0.0029287186135979358 r_2484 PS decarboxylase (1-16:0, 2-18:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-16:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_2485 PS decarboxylase (1-16:1, 2-18:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-16:1, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2486 PS decarboxylase (1-18:0, 2-18:1), vacuolar membrane 0.09853409090909093 prot_P53037 + phosphatidyl-L-serine (1-18:0, 2-18:1) --> carbon dioxide + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3033,7 +3033,7 @@ r_2487 PS decarboxylase (1-18:1, 2-18:1), vacuolar membrane 0.09853409090909093 r_2488 PE methyltransferase (1-16:0, 2-16:1), ER membrane 1627.5240996397504 prot_P05374 + phosphatidylethanolamine (1-16:0, 2-16:1) + S-adenosyl-L-methionine --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) 0.0 r_2489 PE methyltransferase (1-16:1, 2-16:1), ER membrane 1772.794398518638 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) 0.0 r_2490 PE methyltransferase (1-18:0, 2-16:1), ER membrane 2311.996703472735 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) 0.0 -r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 169.40036397185034 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) 0.01007146320421754 +r_2491 PE methyltransferase (1-18:1, 2-16:1), ER membrane 169.40036397185034 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) 0.010071463204217538 r_2492 PE methyltransferase (1-16:0, 2-18:1), ER membrane 1187.9768182494734 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) 0.0 r_2493 PE methyltransferase (1-16:1, 2-18:1), ER membrane 1927.895637345238 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) 0.0 r_2494 PE methyltransferase (1-18:0, 2-18:1), ER membrane 1845.2830881909267 prot_P05374 + S-adenosyl-L-methionine + phosphatidylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3041,7 +3041,7 @@ r_2495 PE methyltransferase (1-18:1, 2-18:1), ER membrane 1146.7320397250028 pro r_2496 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) 0.0 r_2497 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) 0.0 r_2498 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) 0.0 -r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) 0.01007146320421754 +r_2499 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) 0.010071463204217538 r_2500 phosphatidyl-N-methylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) 0.0 r_2501 phosphatidyl-N-methylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) 0.0 r_2502 phosphatidyl-N-methylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) 0.0 @@ -3049,7 +3049,7 @@ r_2503 phosphatidyl-N-methylethanolamine methyltransferase (1-18:1, 2-18:1), ER r_2504 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2505 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2506 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:0, 2-16:1) 0.0 -r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-16:1) 0.01007146320421754 +r_2507 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:1, 2-16:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:1, 2-16:1) 0.010071463204217538 r_2508 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_2509 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-16:1, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-16:1, 2-18:1) 0.0 r_2510 phosphatidyl-N,N-dimethylethanolamine methyltransferase (1-18:0, 2-18:1), ER membrane 1.2281534298793861 prot_P05375 + S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) --> H+ + S-adenosyl-L-homocysteine + phosphatidylcholine (1-18:0, 2-18:1) 0.0 @@ -3070,7 +3070,7 @@ r_2524 ethanolaminephosphotransferase (1-16:0, 2-18:1), ER membrane 12.259319894 r_2525 ethanolaminephosphotransferase (1-16:1, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-16:1, 2-18:1) 0.0 r_2526 ethanolaminephosphotransferase (1-18:0, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-18:0, 2-18:1) 0.0 r_2527 ethanolaminephosphotransferase (1-18:1, 2-18:1), ER membrane 12.259319894180589 prot_P22140 + diglyceride (1-18:1, 2-18:1) + CDP-ethanolamine --> H+ + CMP + phosphatidylethanolamine (1-18:1, 2-18:1) 0.0 -r_2528_EXP_1 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.006512052340513823 +r_2528_EXP_1 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.006512052340514181 r_2528_EXP_2 cholinephosphotransferase (1-16:0, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-16:1) 0.0 r_2529_EXP_1 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_2529_EXP_2 cholinephosphotransferase (1-16:1, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-16:1) 0.0 @@ -3078,11 +3078,11 @@ r_2530_EXP_1 cholinephosphotransferase (1-18:0, 2-16:1), ER membrane 12.68654168 r_2530_EXP_2 cholinephosphotransferase (1-18:0, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:0, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_2531_EXP_1 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_2531_EXP_2 cholinephosphotransferase (1-18:1, 2-16:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:1, 2-16:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-16:1) 0.0 -r_2532_EXP_1 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0002383540915949086 +r_2532_EXP_1 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.00023835409159523194 r_2532_EXP_2 cholinephosphotransferase (1-16:0, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:0, 2-18:1) 0.0 -r_2533_EXP_1 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0025160586724616647 +r_2533_EXP_1 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0025160586724610016 r_2533_EXP_2 cholinephosphotransferase (1-16:1, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-16:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-16:1, 2-18:1) 0.0 -r_2534_EXP_1 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0008023349197814907 +r_2534_EXP_1 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0008023349197814967 r_2534_EXP_2 cholinephosphotransferase (1-18:0, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:0, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:0, 2-18:1) 0.0 r_2535_EXP_1 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 12.686541687718387 prot_P22140 + diglyceride (1-18:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_2535_EXP_2 cholinephosphotransferase (1-18:1, 2-18:1), ER membrane 14.621154591190642 prot_P17898 + diglyceride (1-18:1, 2-18:1) + CDP-choline --> H+ + CMP + phosphatidylcholine (1-18:1, 2-18:1) 0.0 @@ -4015,7 +4015,7 @@ r_3103 PG phospholipase C (1-16:1, 2-18:1), mitochondrial membrane 0.49034391534 r_3104 PC phospholipase D (1-16:0, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + phosphatidylcholine (1-16:0, 2-16:1) + H2O --> choline + phosphatidate (1-16:0, 2-16:1) 0.0 r_3105 PC phospholipase D (1-16:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-16:1) --> choline + phosphatidate (1-16:1, 2-16:1) 0.0 r_3106 PC phospholipase D (1-18:0, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:0, 2-16:1) --> choline + phosphatidate (1-18:0, 2-16:1) 0.0 -r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:1, 2-16:1) --> choline + phosphatidate (1-18:1, 2-16:1) 0.010068800024351886 +r_3107 PC phospholipase D (1-18:1, 2-16:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:1, 2-16:1) --> choline + phosphatidate (1-18:1, 2-16:1) 0.0100688000243519 r_3108 PC phospholipase D (1-16:0, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:0, 2-18:1) --> choline + phosphatidate (1-16:0, 2-18:1) 0.0 r_3109 PC phospholipase D (1-16:1, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-16:1, 2-18:1) --> choline + phosphatidate (1-16:1, 2-18:1) 0.0 r_3110 PC phospholipase D (1-18:0, 2-18:1), cell envelope 0.013555833333333333 prot_P36126 + H+ + H2O + phosphatidylcholine (1-18:0, 2-18:1) --> choline + phosphatidate (1-18:0, 2-18:1) 0.0 @@ -4632,20 +4632,20 @@ r_3512 stearate transport, cytoplasm-ER membrane stearate --> stearate 0.0 r_3512_REV stearate transport, cytoplasm-ER membrane (reversible) stearate --> stearate 0.0 r_3513 oleate transport, cytoplasm-ER membrane oleate --> oleate 0.0 r_3513_REV oleate transport, cytoplasm-ER membrane (reversible) oleate --> oleate 0.0 -r_3514 malonyl-CoA transport, cytoplasm-ER membrane malonyl-CoA --> malonyl-CoA 0.00377307173587955 +r_3514 malonyl-CoA transport, cytoplasm-ER membrane malonyl-CoA --> malonyl-CoA 0.0037730717358795407 r_3514_REV malonyl-CoA transport, cytoplasm-ER membrane (reversible) malonyl-CoA --> malonyl-CoA 0.0 r_3515 lauroyl-CoA transport, cytoplasm-ER membrane lauroyl-CoA --> lauroyl-CoA 0.0 r_3515_REV lauroyl-CoA transport, cytoplasm-ER membrane (reversible) lauroyl-CoA --> lauroyl-CoA 0.0 r_3516 myristoyl-CoA transport, cytoplasm-ER membrane myristoyl-CoA --> myristoyl-CoA 0.0 r_3516_REV myristoyl-CoA transport, cytoplasm-ER membrane (reversible) myristoyl-CoA --> myristoyl-CoA 0.0 -r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane palmitoyl-CoA --> palmitoyl-CoA 0.03996705668514179 +r_3517 palmitoyl-CoA transport, cytoplasm-ER membrane palmitoyl-CoA --> palmitoyl-CoA 0.0399670566851418 r_3517_REV palmitoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3518 palmitoleoyl-CoA transport, cytoplasm-ER membrane palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 -r_3518_REV palmitoleoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 -r_3519 stearoyl-CoA transport, cytoplasm-ER membrane stearoyl-CoA --> stearoyl-CoA 0.005165768327834141 +r_3518_REV palmitoleoyl-CoA transport, cytoplasm-ER membrane (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.000917181046197385 +r_3519 stearoyl-CoA transport, cytoplasm-ER membrane stearoyl-CoA --> stearoyl-CoA 0.005165768327834138 r_3519_REV stearoyl-CoA transport, cytoplasm-ER membrane (reversible) stearoyl-CoA --> stearoyl-CoA 0.0 r_3520 oleoyl-CoA transport, cytoplasm-ER membrane oleoyl-CoA --> oleoyl-CoA 0.0 -r_3520_REV oleoyl-CoA transport, cytoplasm-ER membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.0008023349197814902 +r_3520_REV oleoyl-CoA transport, cytoplasm-ER membrane (reversible) oleoyl-CoA --> oleoyl-CoA 0.0008023349197814968 r_3521 icosanoyl-CoA transport, cytoplasm-ER membrane icosanoyl-CoA --> icosanoyl-CoA 0.0 r_3521_REV icosanoyl-CoA transport, cytoplasm-ER membrane (reversible) icosanoyl-CoA --> icosanoyl-CoA 0.0 r_3522 docosanoyl-CoA transport, cytoplasm-ER membrane docosanoyl-CoA --> docosanoyl-CoA 0.0 @@ -4655,55 +4655,55 @@ r_3523_REV tetracosanoyl-CoA transport, cytoplasm-ER membrane (reversible) tetra r_3524 hexacosanoyl-CoA transport, cytoplasm-ER membrane hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_3524_REV hexacosanoyl-CoA transport, cytoplasm-ER membrane (reversible) hexacosanoyl-CoA --> hexacosanoyl-CoA 0.0 r_3525 H+ transport, cytoplasm-ER membrane H+ --> H+ 0.0 -r_3525_REV H+ transport, cytoplasm-ER membrane (reversible) H+ --> H+ 0.002464461509404589 +r_3525_REV H+ transport, cytoplasm-ER membrane (reversible) H+ --> H+ 0.0024644615093987396 r_3526_EXP_1 H2O transport, cytoplasm-ER membrane 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_3526_EXP_2 H2O transport, cytoplasm-ER membrane 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 -r_3526_REV_EXP_1 H2O transport, cytoplasm-ER membrane (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.07574987917368178 +r_3526_REV_EXP_1 H2O transport, cytoplasm-ER membrane (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0757498791736818 r_3526_REV_EXP_2 H2O transport, cytoplasm-ER membrane (reversible) 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_3527 CO2 transport, cytoplasm-ER membrane carbon dioxide --> carbon dioxide 0.0 r_3527_REV CO2 transport, cytoplasm-ER membrane (reversible) carbon dioxide --> carbon dioxide 0.00377307173587955 r_3528 coenzyme A transport, cytoplasm-ER membrane coenzyme A --> coenzyme A 0.0 -r_3528_REV coenzyme A transport, cytoplasm-ER membrane (reversible) coenzyme A --> coenzyme A 0.04810356182907226 +r_3528_REV coenzyme A transport, cytoplasm-ER membrane (reversible) coenzyme A --> coenzyme A 0.04718638078287726 r_3529 NADPH transport, cytoplasm-ER membrane NADPH --> NADPH 0.0075461434717591 r_3529_REV NADPH transport, cytoplasm-ER membrane (reversible) NADPH --> NADPH 0.0 r_3530 NADP(+) transport, cytoplasm-ER membrane NADP(+) --> NADP(+) 0.0 r_3530_REV NADP(+) transport, cytoplasm-ER membrane (reversible) NADP(+) --> NADP(+) 0.0075461434717591 -r_3531 O2 transport, cytoplasm-ER membrane oxygen --> oxygen 0.035988403718901114 +r_3531 O2 transport, cytoplasm-ER membrane oxygen --> oxygen 0.03598840371890112 r_3531_REV O2 transport, cytoplasm-ER membrane (reversible) oxygen --> oxygen 0.0 r_3532 NADH transport, cytoplasm-ER membrane NADH --> NADH 0.06807176994920194 r_3532_REV NADH transport, cytoplasm-ER membrane (reversible) NADH --> NADH 0.0 r_3533 NAD transport, cytoplasm-ER membrane NAD --> NAD 0.0 r_3533_REV NAD transport, cytoplasm-ER membrane (reversible) NAD --> NAD 0.06807176994920194 -r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.01936702465100835 +r_3534 glycerol 3-phosphate transport, cytoplasm-ER membrane glycerol 3-phosphate --> glycerol 3-phosphate 0.019367024651010076 r_3534_REV glycerol 3-phosphate transport, cytoplasm-ER membrane (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3535 dihydroxyacetone phosphate transport, cytoplasm-ER membrane dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3535_REV dihydroxyacetone phosphate transport, cytoplasm-ER membrane (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3536 diphosphate transport, cytoplasm-ER membrane diphosphate --> diphosphate 0.0 -r_3536_REV diphosphate transport, cytoplasm-ER membrane (reversible) diphosphate --> diphosphate 0.016050398303281567 +r_3536_REV diphosphate transport, cytoplasm-ER membrane (reversible) diphosphate --> diphosphate 0.016050398303284315 r_3537 phosphate transport, cytoplasm-ER membrane phosphate --> phosphate 0.0 r_3537_REV phosphate transport, cytoplasm-ER membrane (reversible) phosphate --> phosphate 0.0 -r_3538 CTP transport, cytoplasm-ER membrane CTP --> CTP 0.017744243710216323 +r_3538 CTP transport, cytoplasm-ER membrane CTP --> CTP 0.017744243710216302 r_3538_REV CTP transport, cytoplasm-ER membrane (reversible) CTP --> CTP 0.0 r_3539 CDP transport, cytoplasm-ER membrane CDP --> CDP 0.0 r_3539_REV CDP transport, cytoplasm-ER membrane (reversible) CDP --> CDP 0.0 r_3540 CMP transport, cytoplasm-ER membrane CMP --> CMP 0.0 -r_3540_REV CMP transport, cytoplasm-ER membrane (reversible) CMP --> CMP 0.0278130437345682 +r_3540_REV CMP transport, cytoplasm-ER membrane (reversible) CMP --> CMP 0.02781304373456819 r_3541 CDP-ethanolamine transport, cytoplasm-ER membrane CDP-ethanolamine --> CDP-ethanolamine 0.0 r_3541_REV CDP-ethanolamine transport, cytoplasm-ER membrane (reversible) CDP-ethanolamine --> CDP-ethanolamine 0.0 -r_3542 CDP-choline transport, cytoplasm-ER membrane CDP-choline --> CDP-choline 0.010068800024351886 +r_3542 CDP-choline transport, cytoplasm-ER membrane CDP-choline --> CDP-choline 0.0100688000243519 r_3542_REV CDP-choline transport, cytoplasm-ER membrane (reversible) CDP-choline --> CDP-choline 0.0 r_3543 ATP transport, cytoplasm-ER membrane ATP --> ATP 0.0 r_3543_REV ATP transport, cytoplasm-ER membrane (reversible) ATP --> ATP 0.0016938454069323457 r_3544 AMP transport, cytoplasm-ER membrane AMP --> AMP 0.0016938454069323457 r_3544_REV AMP transport, cytoplasm-ER membrane (reversible) AMP --> AMP 0.0 -r_3545 L-serine transport, cytoplasm-ER membrane 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.015350228848248493 +r_3545 L-serine transport, cytoplasm-ER membrane 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.015350228848250894 r_3545_REV L-serine transport, cytoplasm-ER membrane (reversible) 3.1230091119005747 prot_P19145 + L-serine --> L-serine 0.0 -r_3546 myo-inositol transport, cytoplasm-ER membrane myo-inositol --> myo-inositol 0.0023940148619654186 +r_3546 myo-inositol transport, cytoplasm-ER membrane myo-inositol --> myo-inositol 0.0023940148619654065 r_3546_REV myo-inositol transport, cytoplasm-ER membrane (reversible) myo-inositol --> myo-inositol 0.0 -r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.030214389612652617 +r_3547 S-adenosyl-L-methionine transport, cytoplasm-ER membrane S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.03021438961265261 r_3547_REV S-adenosyl-L-methionine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-methionine --> S-adenosyl-L-methionine 0.0 r_3548 S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.0 -r_3548_REV S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.030214389612652617 +r_3548_REV S-adenosyl-L-homocysteine transport, cytoplasm-ER membrane (reversible) S-adenosyl-L-homocysteine --> S-adenosyl-L-homocysteine 0.03021438961265261 r_3549 episterol transport, cytoplasm-ER membrane episterol --> episterol 0.0 r_3549_REV episterol transport, cytoplasm-ER membrane (reversible) episterol --> episterol 0.0 r_3550 fecosterol transport, cytoplasm-ER membrane fecosterol --> fecosterol 0.0 @@ -4711,13 +4711,13 @@ r_3550_REV fecosterol transport, cytoplasm-ER membrane (reversible) fecosterol - r_3551 lanosterol transport, cytoplasm-ER membrane lanosterol --> lanosterol 0.0 r_3551_REV lanosterol transport, cytoplasm-ER membrane (reversible) lanosterol --> lanosterol 0.0 r_3552 ergosterol transport, cytoplasm-ER membrane ergosterol --> ergosterol 0.0 -r_3552_REV ergosterol transport, cytoplasm-ER membrane (reversible) ergosterol --> ergosterol 0.007709041072055719 +r_3552_REV ergosterol transport, cytoplasm-ER membrane (reversible) ergosterol --> ergosterol 0.0 r_3553 zymosterol transport, cytoplasm-ER membrane zymosterol --> zymosterol 0.0 r_3553_REV zymosterol transport, cytoplasm-ER membrane (reversible) zymosterol --> zymosterol 0.0 r_3554 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3554_REV diglyceride (1-16:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3555 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 -r_3555_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0015079348143778807 +r_3555_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0024251158605752597 r_3556 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3556_REV diglyceride (1-18:0, 2-16:1) transport, cytoplasm-ER membrane (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3557 diglyceride (1-18:1, 2-16:1) transport, cytoplasm-ER membrane diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 @@ -4739,7 +4739,7 @@ r_3564_REV 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) transport, cytoplasm- r_3565 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 r_3565_REV 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) 0.0 r_3566 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0 -r_3566_REV 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0023940148619654186 +r_3566_REV 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) 0.0023940148619657656 r_3567 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 0.0 r_3567_REV 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) transport, cytoplasm-ER membrane (reversible) 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) 0.0 r_3568 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) transport, cytoplasm-ER membrane 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) 0.0 @@ -4762,13 +4762,13 @@ r_3576 myristoyl-CoA transport, cytoplasm-lipid particle myristoyl-CoA --> myris r_3576_REV myristoyl-CoA transport, cytoplasm-lipid particle (reversible) myristoyl-CoA --> myristoyl-CoA 0.0 r_3577 palmitoyl-CoA transport, cytoplasm-lipid particle palmitoyl-CoA --> palmitoyl-CoA 0.0 r_3577_REV palmitoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoyl-CoA --> palmitoyl-CoA 0.0 -r_3578 palmitoleoyl-CoA transport, cytoplasm-lipid particle palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 +r_3578 palmitoleoyl-CoA transport, cytoplasm-lipid particle palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.000917181046197385 r_3578_REV palmitoleoyl-CoA transport, cytoplasm-lipid particle (reversible) palmitoleoyl-CoA(4-) --> palmitoleoyl-CoA(4-) 0.0 r_3579 stearoyl-CoA transport, cytoplasm-lipid particle stearoyl-CoA --> stearoyl-CoA 0.0023102697341593715 r_3579_REV stearoyl-CoA transport, cytoplasm-lipid particle (reversible) stearoyl-CoA --> stearoyl-CoA 0.0 -r_3580 oleoyl-CoA transport, cytoplasm-lipid particle oleoyl-CoA --> oleoyl-CoA 0.0008023349197814902 +r_3580 oleoyl-CoA transport, cytoplasm-lipid particle oleoyl-CoA --> oleoyl-CoA 0.0008023349197814968 r_3580_REV oleoyl-CoA transport, cytoplasm-lipid particle (reversible) oleoyl-CoA --> oleoyl-CoA 0.0 -r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle glycerol 3-phosphate --> glycerol 3-phosphate 0.0008023349197814906 +r_3581 glycerol 3-phosphate transport, cytoplasm-lipid particle glycerol 3-phosphate --> glycerol 3-phosphate 0.0008023349197814968 r_3581_REV glycerol 3-phosphate transport, cytoplasm-lipid particle (reversible) glycerol 3-phosphate --> glycerol 3-phosphate 0.0 r_3582 dihydroxyacetone phosphate transport, cytoplasm-lipid particle dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 r_3582_REV dihydroxyacetone phosphate transport, cytoplasm-lipid particle (reversible) dihydroxyacetone phosphate --> dihydroxyacetone phosphate 0.0 @@ -4784,7 +4784,7 @@ r_3587 diphosphate transport, cytoplasm-lipid particle diphosphate --> diphospha r_3587_REV diphosphate transport, cytoplasm-lipid particle (reversible) diphosphate --> diphosphate 0.0 r_3588 diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 r_3588_REV diglyceride (1-16:0, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3589 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0015079348143778807 +r_3589 diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0024251158605752597 r_3589_REV diglyceride (1-16:1, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3590 diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 r_3590_REV diglyceride (1-18:0, 2-16:1) transport, cytoplasm-lipid particle (reversible) diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 @@ -4812,10 +4812,10 @@ r_3601 ATP transport, cytoplasm-cell envelope ATP --> ATP 0.0 r_3601_REV ATP transport, cytoplasm-cell envelope (reversible) ATP --> ATP 0.0 r_3602 ADP transport, cytoplasm-cell envelope ADP --> ADP 0.0 r_3602_REV ADP transport, cytoplasm-cell envelope (reversible) ADP --> ADP 0.0 -r_3603 H+ transport, cytoplasm-cell envelope H+ --> H+ 0.010068800024351886 +r_3603 H+ transport, cytoplasm-cell envelope H+ --> H+ 0.0100688000243519 r_3603_REV H+ transport, cytoplasm-cell envelope (reversible) H+ --> H+ 0.0 r_3604_EXP_1 H2O transport, cytoplasm-cell envelope 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 -r_3604_EXP_2 H2O transport, cytoplasm-cell envelope 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.010068800024351886 +r_3604_EXP_2 H2O transport, cytoplasm-cell envelope 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0100688000243519 r_3604_EXP_3 H2O transport, cytoplasm-cell envelope 0.8260858585858586 prot_P0CD91 + H2O --> H2O 0.0 r_3604_REV_EXP_1 H2O transport, cytoplasm-cell envelope (reversible) 0.4298989898989899 prot_P0CD90 + H2O --> H2O 0.0 r_3604_REV_EXP_2 H2O transport, cytoplasm-cell envelope (reversible) 0.41555555555555557 prot_P0CD98 + H2O --> H2O 0.0 @@ -4921,7 +4921,7 @@ r_3651_REV ATP transport, cytoplasm-vacuolar membrane (reversible) ATP --> ATP 0 r_3652 ADP transport, cytoplasm-vacuolar membrane ADP --> ADP 0.0 r_3652_REV ADP transport, cytoplasm-vacuolar membrane (reversible) ADP --> ADP 0.0 r_3653 carbon dioxide transport, cytoplasm-vacuolar membrane carbon dioxide --> carbon dioxide 0.0 -r_3653_REV carbon dioxide transport, cytoplasm-vacuolar membrane (reversible) carbon dioxide --> carbon dioxide 0.0029287186135979392 +r_3653_REV carbon dioxide transport, cytoplasm-vacuolar membrane (reversible) carbon dioxide --> carbon dioxide 0.0029287186135979358 r_3654 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) transport, vacuolar membrane-cytoplasm 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) 0.0 r_3654_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) 0.0 r_3655 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) transport, vacuolar membrane-cytoplasm 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) 0.0 @@ -4938,12 +4938,12 @@ r_3660 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transpor r_3660_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) 0.0 r_3661 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 r_3661_REV 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) transport, vacuolar membrane-cytoplasm (reversible) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) --> 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) 0.0 -r_3662 H2O transport, cytoplasm-Golgi membrane H2O --> H2O 0.012493915884927145 +r_3662 H2O transport, cytoplasm-Golgi membrane H2O --> H2O 0.012493915884927173 r_3662_REV H2O transport, cytoplasm-Golgi membrane (reversible) H2O --> H2O 0.0 r_3663 phosphate transport, cytoplasm-Golgi membrane phosphate --> phosphate 0.0 -r_3663_REV phosphate transport, cytoplasm-Golgi membrane (reversible) phosphate --> phosphate 0.012493915884927145 +r_3663_REV phosphate transport, cytoplasm-Golgi membrane (reversible) phosphate --> phosphate 0.012493915884927173 r_3664 H+ transport, cytoplasm-Golgi membrane H+ --> H+ 0.0 -r_3664_REV H+ transport, cytoplasm-Golgi membrane (reversible) H+ --> H+ 0.02498783176985429 +r_3664_REV H+ transport, cytoplasm-Golgi membrane (reversible) H+ --> H+ 0.024987831769854345 r_3665 carbon dioxide transport, cytoplasm-Golgi membrane carbon dioxide --> carbon dioxide 0.0 r_3665_REV carbon dioxide transport, cytoplasm-Golgi membrane (reversible) carbon dioxide --> carbon dioxide 0.0 r_3666 ATP transport, cytoplasm-Golgi membrane ATP --> ATP 0.0 @@ -4995,9 +4995,9 @@ r_3688_REV TAG (1-16:0, 2-16:1, 3-18:1) transport, ER membrane-lipid particle (r r_3689 TAG (1-16:1, 2-16:1, 3-16:0) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-16:0) --> triglyceride (1-16:1, 2-16:1, 3-16:0) 0.0 r_3689_REV TAG (1-16:1, 2-16:1, 3-16:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-16:0) --> triglyceride (1-16:1, 2-16:1, 3-16:0) 0.0 r_3690 TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 -r_3690_REV TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.0 +r_3690_REV TAG (1-16:1, 2-16:1, 3-16:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-16:1) --> triglyceride (1-16:1, 2-16:1, 3-16:1) 0.000917181046197385 r_3691 TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0 -r_3691_REV TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0015079348143778807 +r_3691_REV TAG (1-16:1, 2-16:1, 3-18:0) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-18:0) --> triglyceride (1-16:1, 2-16:1, 3-18:0) 0.0015079348143778749 r_3692 TAG (1-16:1, 2-16:1, 3-18:1) transport, ER membrane-lipid particle triglyceride (1-16:1, 2-16:1, 3-18:1) --> triglyceride (1-16:1, 2-16:1, 3-18:1) 0.0 r_3692_REV TAG (1-16:1, 2-16:1, 3-18:1) transport, ER membrane-lipid particle (reversible) triglyceride (1-16:1, 2-16:1, 3-18:1) --> triglyceride (1-16:1, 2-16:1, 3-18:1) 0.0 r_3693 TAG (1-18:0, 2-16:1, 3-16:0) transport, ER membrane-lipid particle triglyceride (1-18:0, 2-16:1, 3-16:0) --> triglyceride (1-18:0, 2-16:1, 3-16:0) 0.0 @@ -5128,7 +5128,7 @@ r_3755 phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane phos r_3755_REV phosphatidate (1-16:0, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3756 phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 r_3756_REV phosphatidate (1-16:1, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0008023349197814907 +r_3757 phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0008023349197814968 r_3757_REV phosphatidate (1-18:0, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 r_3758 phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3758_REV phosphatidate (1-18:1, 2-18:1) transport, lipid particle-ER membrane (reversible) phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 @@ -5193,7 +5193,7 @@ r_3787_REV phosphatidylcholine (1-18:0, 2-18:1) transport, ER membrane-mitochond r_3788 phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane phosphatidylcholine (1-18:1, 2-18:1) --> phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_3788_REV phosphatidylcholine (1-18:1, 2-18:1) transport, ER membrane-mitochondrial membrane (reversible) phosphatidylcholine (1-18:1, 2-18:1) --> phosphatidylcholine (1-18:1, 2-18:1) 0.0 r_3789 diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.0 -r_3789_REV diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.006512052340513823 +r_3789_REV diglyceride (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-16:1) --> diglyceride (1-16:0, 2-16:1) 0.006512052340514181 r_3790 diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0 r_3790_REV diglyceride (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-16:1) --> diglyceride (1-16:1, 2-16:1) 0.0024251158605752597 r_3791 diglyceride (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-18:0, 2-16:1) --> diglyceride (1-18:0, 2-16:1) 0.0 @@ -5201,14 +5201,14 @@ r_3791_REV diglyceride (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane (r r_3792 diglyceride (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3792_REV diglyceride (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:1, 2-16:1) --> diglyceride (1-18:1, 2-16:1) 0.0 r_3793 diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0 -r_3793_REV diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.0002383540915949086 +r_3793_REV diglyceride (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:0, 2-18:1) --> diglyceride (1-16:0, 2-18:1) 0.00023835409159523194 r_3794 diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0 -r_3794_REV diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0025160586724616647 +r_3794_REV diglyceride (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-16:1, 2-18:1) --> diglyceride (1-16:1, 2-18:1) 0.0025160586724610016 r_3795 diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0 -r_3795_REV diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0008023349197814907 +r_3795_REV diglyceride (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:0, 2-18:1) --> diglyceride (1-18:0, 2-18:1) 0.0008023349197814967 r_3796 diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 r_3796_REV diglyceride (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) diglyceride (1-18:1, 2-18:1) --> diglyceride (1-18:1, 2-18:1) 0.0 -r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.006512052340513823 +r_3797 phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.006512052340514181 r_3797_REV phosphatidate (1-16:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:0, 2-16:1) --> phosphatidate (1-16:0, 2-16:1) 0.0 r_3798 phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0024251158605752597 r_3798_REV phosphatidate (1-16:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 @@ -5216,11 +5216,11 @@ r_3799 phosphatidate (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane phos r_3799_REV phosphatidate (1-18:0, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3800 phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3800_REV phosphatidate (1-18:1, 2-16:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 -r_3801 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0002383540915949086 +r_3801 phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.00023835409159523194 r_3801_REV phosphatidate (1-16:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 -r_3802 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0025160586724616647 +r_3802 phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0025160586724610016 r_3802_REV phosphatidate (1-16:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-16:1, 2-18:1) --> phosphatidate (1-16:1, 2-18:1) 0.0 -r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0008023349197814907 +r_3803 phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0008023349197814968 r_3803_REV phosphatidate (1-18:0, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:0, 2-18:1) --> phosphatidate (1-18:0, 2-18:1) 0.0 r_3804 phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 r_3804_REV phosphatidate (1-18:1, 2-18:1) transport, ER membrane-Golgi membrane (reversible) phosphatidate (1-18:1, 2-18:1) --> phosphatidate (1-18:1, 2-18:1) 0.0 @@ -5326,7 +5326,7 @@ r_3846 phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-vacuolar me r_3846_REV phosphatidyl-L-serine (1-16:1, 2-16:1) transport, ER membrane-vacuolar membrane (reversible) phosphatidyl-L-serine (1-16:1, 2-16:1) --> phosphatidyl-L-serine (1-16:1, 2-16:1) 0.0 r_3847 phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-vacuolar membrane phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 r_3847_REV phosphatidyl-L-serine (1-18:0, 2-16:1) transport, ER membrane-vacuolar membrane (reversible) phosphatidyl-L-serine (1-18:0, 2-16:1) --> phosphatidyl-L-serine (1-18:0, 2-16:1) 0.0 -r_3848 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-vacuolar membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0029287186135979392 +r_3848 phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-vacuolar membrane phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0029287186135979358 r_3848_REV phosphatidyl-L-serine (1-18:1, 2-16:1) transport, ER membrane-vacuolar membrane (reversible) phosphatidyl-L-serine (1-18:1, 2-16:1) --> phosphatidyl-L-serine (1-18:1, 2-16:1) 0.0 r_3849 phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-vacuolar membrane phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 r_3849_REV phosphatidyl-L-serine (1-16:0, 2-18:1) transport, ER membrane-vacuolar membrane (reversible) phosphatidyl-L-serine (1-16:0, 2-18:1) --> phosphatidyl-L-serine (1-16:0, 2-18:1) 0.0 @@ -5342,7 +5342,7 @@ r_3854 phosphatidylethanolamine (1-16:1, 2-16:1) transport, vacuolar membrane-ER r_3854_REV phosphatidylethanolamine (1-16:1, 2-16:1) transport, vacuolar membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:1, 2-16:1) --> phosphatidylethanolamine (1-16:1, 2-16:1) 0.0 r_3855 phosphatidylethanolamine (1-18:0, 2-16:1) transport, vacuolar membrane-ER membrane phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 r_3855_REV phosphatidylethanolamine (1-18:0, 2-16:1) transport, vacuolar membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:0, 2-16:1) --> phosphatidylethanolamine (1-18:0, 2-16:1) 0.0 -r_3856 phosphatidylethanolamine (1-18:1, 2-16:1) transport, vacuolar membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0029287186135979392 +r_3856 phosphatidylethanolamine (1-18:1, 2-16:1) transport, vacuolar membrane-ER membrane phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0029287186135979358 r_3856_REV phosphatidylethanolamine (1-18:1, 2-16:1) transport, vacuolar membrane-ER membrane (reversible) phosphatidylethanolamine (1-18:1, 2-16:1) --> phosphatidylethanolamine (1-18:1, 2-16:1) 0.0 r_3857 phosphatidylethanolamine (1-16:0, 2-18:1) transport, vacuolar membrane-ER membrane phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 r_3857_REV phosphatidylethanolamine (1-16:0, 2-18:1) transport, vacuolar membrane-ER membrane (reversible) phosphatidylethanolamine (1-16:0, 2-18:1) --> phosphatidylethanolamine (1-16:0, 2-18:1) 0.0 @@ -5390,7 +5390,7 @@ r_3878 phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope r_3878_REV phosphatidylcholine (1-16:1, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:1, 2-16:1) --> phosphatidylcholine (1-16:1, 2-16:1) 0.0 r_3879 phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 r_3879_REV phosphatidylcholine (1-18:0, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-18:0, 2-16:1) --> phosphatidylcholine (1-18:0, 2-16:1) 0.0 -r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.010068800024351886 +r_3880 phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0100688000243519 r_3880_REV phosphatidylcholine (1-18:1, 2-16:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-18:1, 2-16:1) --> phosphatidylcholine (1-18:1, 2-16:1) 0.0 r_3881 phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 r_3881_REV phosphatidylcholine (1-16:0, 2-18:1) transport, ER membrane-cell envelope (reversible) phosphatidylcholine (1-16:0, 2-18:1) --> phosphatidylcholine (1-16:0, 2-18:1) 0.0 @@ -5442,7 +5442,7 @@ r_3904 phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane phosp r_3904_REV phosphatidate (1-16:1, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:1, 2-16:1) --> phosphatidate (1-16:1, 2-16:1) 0.0 r_3905 phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 r_3905_REV phosphatidate (1-18:0, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-18:0, 2-16:1) --> phosphatidate (1-18:0, 2-16:1) 0.0 -r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.010068800024351886 +r_3906 phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0100688000243519 r_3906_REV phosphatidate (1-18:1, 2-16:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-18:1, 2-16:1) --> phosphatidate (1-18:1, 2-16:1) 0.0 r_3907 phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 r_3907_REV phosphatidate (1-16:0, 2-18:1) transport, cell envelope-ER membrane (reversible) phosphatidate (1-16:0, 2-18:1) --> phosphatidate (1-16:0, 2-18:1) 0.0 @@ -5508,7 +5508,7 @@ r_3937 lignoceric acid transport, ER membrane-ER lignoceric acid --> lignoceric r_3937_REV lignoceric acid transport, ER membrane-ER (reversible) lignoceric acid --> lignoceric acid 0.0 r_3938 cerotic acid transport, ER membrane-ER cerotic acid --> cerotic acid 0.0 r_3938_REV cerotic acid transport, ER membrane-ER (reversible) cerotic acid --> cerotic acid 0.0 -r_3939 ergosterol transport, ER-ER membrane ergosterol --> ergosterol 0.010694455410100273 +r_3939 ergosterol transport, ER-ER membrane ergosterol --> ergosterol 0.0029854143380445546 r_3939_REV ergosterol transport, ER-ER membrane (reversible) ergosterol --> ergosterol 0.0 r_3940 phosphate transport, ER-ER membrane phosphate --> phosphate 0.0 r_3941 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) transport, vacuolar membrane-Golgi membrane 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) --> 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) 0.0 @@ -5561,7 +5561,7 @@ r_3963 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) [cytoplasm] SLIME rxn 1-p r_3964 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) --> 0.807012462 1-phosphatidyl-1D-myo-inositol backbone + 0.508826 C16:1 chain 0.0 r_3965 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_3966 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_3967 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0023940148619654186 +r_3967 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) --> 0.837082102 1-phosphatidyl-1D-myo-inositol backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0023940148619657656 r_3968 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) --> 0.835066222 1-phosphatidyl-1D-myo-inositol backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_3969 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) --> 0.865135862 1-phosphatidyl-1D-myo-inositol backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_3970 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) [cytoplasm] SLIME rxn 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) --> 0.863119982 1-phosphatidyl-1D-myo-inositol backbone + 0.56493352 C18:1 chain 0.0 @@ -5574,7 +5574,7 @@ r_3976 palmitoleate [cytoplasm] SLIME rxn H+ + palmitoleate --> 0.25340506 fatty r_3977 stearate [cytoplasm] SLIME rxn H+ + stearate --> 0.2834747 fatty acid backbone + 0.28448264 C18:0 chain 0.0 r_3978 oleate [cytoplasm] SLIME rxn H+ + oleate --> 0.28145882 fatty acid backbone + 0.28246676 C18:1 chain 0.0 r_3979 phosphatidyl-L-serine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:0, 2-16:1) --> 0.733964182 phosphatidyl-L-serine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.0 -r_3980 phosphatidyl-L-serine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:1, 2-16:1) --> 0.731948302 phosphatidyl-L-serine backbone + 0.508826 C16:1 chain 0.0023577239680860405 +r_3980 phosphatidyl-L-serine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:1, 2-16:1) --> 0.731948302 phosphatidyl-L-serine backbone + 0.508826 C16:1 chain 0.0023577239680884435 r_3981 phosphatidyl-L-serine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:0, 2-16:1) --> 0.762017942 phosphatidyl-L-serine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_3982 phosphatidyl-L-serine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:1, 2-16:1) --> 0.760002062 phosphatidyl-L-serine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_3983 phosphatidyl-L-serine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-16:0, 2-18:1) --> 0.762017942 phosphatidyl-L-serine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5583,13 +5583,13 @@ r_3985 phosphatidyl-L-serine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] S r_3986 phosphatidyl-L-serine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidyl-L-serine (1-18:1, 2-18:1) --> 0.788055822 phosphatidyl-L-serine backbone + 0.56493352 C18:1 chain 0.0 r_3987 phosphatidyl-L-serine transport, ER membrane-cytoplasm phosphatidyl-L-serine backbone --> phosphatidyl-L-serine backbone 0.0017257320550270387 r_3987_REV phosphatidyl-L-serine transport, ER membrane-cytoplasm (reversible) phosphatidyl-L-serine backbone --> phosphatidyl-L-serine backbone 0.0 -r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-16:1) --> 0.732035022 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.006512052340513823 +r_3988 phosphatidylcholine (1-16:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-16:1) --> 0.732035022 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain 0.006512052340514181 r_3989 phosphatidylcholine (1-16:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-16:1) --> 0.730019142 phosphatidylcholine backbone + 0.508826 C16:1 chain 0.0 r_3990 phosphatidylcholine (1-18:0, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-16:1) --> 0.744089382 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 -r_3991 phosphatidylcholine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-16:1) --> 0.742073502 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 2.663179865653592e-06 -r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-18:1) --> 0.760088782 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.0002383540915949086 -r_3993 phosphatidylcholine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-18:1) --> 0.758072902 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0025160586724616647 -r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-18:1) --> 0.772143142 phosphatidylcholine backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0008023349197814907 +r_3991 phosphatidylcholine (1-18:1, 2-16:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-16:1) --> 0.742073502 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 2.6631798656379796e-06 +r_3992 phosphatidylcholine (1-16:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:0, 2-18:1) --> 0.760088782 phosphatidylcholine backbone + 0.25642888 C16:0 chain + 0.28246676 C18:1 chain 0.00023835409159523194 +r_3993 phosphatidylcholine (1-16:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-16:1, 2-18:1) --> 0.758072902 phosphatidylcholine backbone + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0025160586724610016 +r_3994 phosphatidylcholine (1-18:0, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:0, 2-18:1) --> 0.772143142 phosphatidylcholine backbone + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0008023349197814967 r_3995 phosphatidylcholine (1-18:1, 2-18:1) [endoplasmic reticulum membrane] SLIME rxn phosphatidylcholine (1-18:1, 2-18:1) --> 0.770127262 phosphatidylcholine backbone + 0.56493352 C18:1 chain 0.0 r_3996 phosphatidylcholine transport, ER membrane-cytoplasm phosphatidylcholine backbone --> phosphatidylcholine backbone 0.007477070230059319 r_3996_REV phosphatidylcholine transport, ER membrane-cytoplasm (reversible) phosphatidylcholine backbone --> phosphatidylcholine backbone 0.0 @@ -5613,7 +5613,7 @@ r_4012 triglyceride (1-18:1, 2-16:1, 3-16:0) [endoplasmic reticulum membrane] SL r_4013 triglyceride (1-18:1, 2-18:1, 3-16:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-16:0) --> 0.85941128 triglyceride backbone + 0.25642888 C16:0 chain + 0.56493352 C18:1 chain 0.0 r_4014 triglyceride (1-16:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-16:1) --> 0.80330376 triglyceride backbone + 0.25642888 C16:0 chain + 0.508826 C16:1 chain 0.0 r_4015 triglyceride (1-16:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-18:1, 3-16:1) --> 0.83135752 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28246676 C18:1 chain 0.0 -r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-16:1) --> 0.80128788 triglyceride backbone + 0.763239 C16:1 chain 0.0009171810461973788 +r_4016 triglyceride (1-16:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-16:1) --> 0.80128788 triglyceride backbone + 0.763239 C16:1 chain 0.000917181046197385 r_4017 triglyceride (1-16:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-18:1, 3-16:1) --> 0.82934164 triglyceride backbone + 0.508826 C16:1 chain + 0.28246676 C18:1 chain 0.0 r_4018 triglyceride (1-18:0, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-16:1, 3-16:1) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_4019 triglyceride (1-18:0, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-18:1, 3-16:1) --> 0.85941128 triglyceride backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5621,7 +5621,7 @@ r_4020 triglyceride (1-18:1, 2-16:1, 3-16:1) [endoplasmic reticulum membrane] SL r_4021 triglyceride (1-18:1, 2-18:1, 3-16:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-16:1) --> 0.8573954 triglyceride backbone + 0.254413 C16:1 chain + 0.56493352 C18:1 chain 0.0 r_4022 triglyceride (1-16:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-16:1, 3-18:0) --> 0.8333734 triglyceride backbone + 0.25642888 C16:0 chain + 0.254413 C16:1 chain + 0.28448264 C18:0 chain 0.0 r_4023 triglyceride (1-16:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:0, 2-18:1, 3-18:0) --> 0.86142716 triglyceride backbone + 0.25642888 C16:0 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 -r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-18:0) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0015079348143778807 +r_4024 triglyceride (1-16:1, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-16:1, 3-18:0) --> 0.83135752 triglyceride backbone + 0.508826 C16:1 chain + 0.28448264 C18:0 chain 0.0015079348143778749 r_4025 triglyceride (1-16:1, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-16:1, 2-18:1, 3-18:0) --> 0.85941128 triglyceride backbone + 0.254413 C16:1 chain + 0.28448264 C18:0 chain + 0.28246676 C18:1 chain 0.0 r_4026 triglyceride (1-18:0, 2-16:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-16:1, 3-18:0) --> 0.86142716 triglyceride backbone + 0.254413 C16:1 chain + 0.56896528 C18:0 chain 0.0 r_4027 triglyceride (1-18:0, 2-18:1, 3-18:0) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:0, 2-18:1, 3-18:0) --> 0.88948092 triglyceride backbone + 0.56896528 C18:0 chain + 0.28246676 C18:1 chain 0.0 @@ -5637,7 +5637,7 @@ r_4036 triglyceride (1-18:1, 2-16:1, 3-18:1) [endoplasmic reticulum membrane] SL r_4037 triglyceride (1-18:1, 2-18:1, 3-18:1) [endoplasmic reticulum membrane] SLIME rxn triglyceride (1-18:1, 2-18:1, 3-18:1) --> 0.88544916 triglyceride backbone + 0.84740028 C18:1 chain 0.0 r_4038 triglyceride transport, ER membrane-cytoplasm triglyceride backbone --> triglyceride backbone 0.001988559003686535 r_4038_REV triglyceride transport, ER membrane-cytoplasm (reversible) triglyceride backbone --> triglyceride backbone 0.0 -r_4039 succinyl-CoA:acetate CoA transferase 2.0420759036703515 prot_P32316 + acetate + succinyl-CoA --> acetyl-CoA + succinate 2.104944131511068 +r_4039 succinyl-CoA:acetate CoA transferase 2.0420759036703515 prot_P32316 + acetate + succinyl-CoA --> acetyl-CoA + succinate 0.39788858520808457 r_4039_REV succinyl-CoA:acetate CoA transferase (reversible) 2.24640342822161 prot_P32316 + acetyl-CoA + succinate --> acetate + succinyl-CoA 0.0 r_4040 heme a transport heme a --> heme a 2.899999992678204e-07 r_4040_REV heme a transport (reversible) heme a --> heme a 0.0 @@ -5944,7 +5944,7 @@ r_4212_REV_EXP_2 D-ribulose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5 r_4214 L-cysteinylglycine dipeptidase 0.44291358035466905 prot_P43616 + H2O + L-cysteinylglycine --> L-cysteine + L-glycine 0.0 r_4214_REV L-cysteinylglycine dipeptidase (reversible) 1.1513279129330525 prot_P43616 + L-cysteine + L-glycine --> H2O + L-cysteinylglycine 0.0 r_4216 riboflavin-5-phosphate phosphohydrolase 2.307741115456161 prot_P52290 + FMN + H2O --> phosphate + riboflavin 0.0 -r_4216_REV riboflavin-5-phosphate phosphohydrolase (reversible) 1.7221699633075207 prot_P52290 + phosphate + riboflavin --> FMN + H2O 2.899999926739825e-06 +r_4216_REV riboflavin-5-phosphate phosphohydrolase (reversible) 1.7221699633075207 prot_P52290 + phosphate + riboflavin --> FMN + H2O 0.0 r_4217 Fe(II):oxygen oxidoreductase; Fe2+:oxygen oxidoreductase 2.4608585858585856 prot_Q07540 + 4.0 H+ + 4.0 iron(2+) + oxygen --> 2.0 H2O + 4.0 iron(3+) 0.0 r_4217_REV Fe(II):oxygen oxidoreductase; Fe2+:oxygen oxidoreductase (reversible) 2.4608585858585856 prot_Q07540 + 2.0 H2O + 4.0 iron(3+) --> 4.0 H+ + 4.0 iron(2+) + oxygen 0.0 r_4218 D-aminoacyl-tRNA deacylase (DTD) (EC 3.1.1.96) (D-tyrosyl-tRNA(Tyr) deacylase) (Gly-tRNA(Ala) deacylase) (EC 3.1.1.-) 0.015505555555555555 prot_Q07648 + H2O + Glycyl-tRNA(Ala) --> H+ + L-glycine + tRNA(Ala) 0.0 @@ -6136,8 +6136,8 @@ r_4332 Protein PNS1 (pH nine-sensitive protein 1) 4.890140948879145 prot_Q12412 r_4332_REV Protein PNS1 (pH nine-sensitive protein 1) (reversible) 4.890140948879145 prot_Q12412 + choline --> choline 0.0 r_4333_EXP_1 Polyphosphate phosphohydrolase 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4333_EXP_2 Polyphosphate phosphohydrolase 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 -r_4333_REV_EXP_1 Polyphosphate phosphohydrolase (reversible) 0.008073655913978494 prot_P38698 + H+ + 2.0 phosphate --> H2O + polyphosphate 8.062066960679834 -r_4333_REV_EXP_2 Polyphosphate phosphohydrolase (reversible) 0.014040143369175627 prot_Q04119 + H+ + 2.0 phosphate --> H2O + polyphosphate 0.9921853736075817 +r_4333_REV_EXP_1 Polyphosphate phosphohydrolase (reversible) 0.008073655913978494 prot_P38698 + H+ + 2.0 phosphate --> H2O + polyphosphate 9.246287943908685 +r_4333_REV_EXP_2 Polyphosphate phosphohydrolase (reversible) 0.014040143369175627 prot_Q04119 + H+ + 2.0 phosphate --> H2O + polyphosphate 0.0 r_4334 Copper-transporting ATPase (EC 3.6.3.54) (Cu(2+)-ATPase) 117.33867521367522 prot_P38995 + ATP + H2O + Cu2(+) --> ADP + H+ + phosphate + Cu2(+) 0.0 r_4335 Endopolyphosphatase (EC 3.6.1.10) (Deoxyadenosine triphosphate phosphohydrolase) (dATP phosphohydrolase) (EC 3.6.1.-) (Exopolyphosphatase) (EC 3.6.1.11) (Phosphate metabolism protein 5) 0.014040143369175627 prot_Q04119 + dATP + H2O --> dADP + H+ + phosphate 0.0 r_4336 Monoamide of a dicarboxylic acid amidohydrolase 0.12436573437261195 prot_P49954 + H2O + 2-Oxoglutaramate --> 2-oxoglutarate + ammonium 0.0 @@ -6481,17 +6481,17 @@ r_4567 6-phosphogluconate phosphatase 0.17308256172839506 prot_standard + 6-phos r_4569 Carboxylic ester hydrolases 0.45405614353626883 prot_standard + acetate + H+ + Hydroquinone --> H2O + 4-hydroxyphenyl acetate 0.0 r_4570_EXP_1 phosphoglycerate dehydrogenase 0.0036932178932178933 prot_P40510 + NAD + 2-hydroxyglutarate --> 2-oxoglutarate + H+ + NADH 0.0 r_4570_EXP_2 phosphoglycerate dehydrogenase 0.0036935786435786434 prot_P40054 + NAD + 2-hydroxyglutarate --> 2-oxoglutarate + H+ + NADH 0.0 -r_4570_REV_EXP_1 phosphoglycerate dehydrogenase (reversible) 0.005777687480247415 prot_P40510 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.06604454794825777 +r_4570_REV_EXP_1 phosphoglycerate dehydrogenase (reversible) 0.005777687480247415 prot_P40510 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.06654523127145702 r_4570_REV_EXP_2 phosphoglycerate dehydrogenase (reversible) 0.0057782518398121815 prot_P40054 + 2-oxoglutarate + H+ + NADH --> NAD + 2-hydroxyglutarate 0.0 -r_4571 seed:rxn00681 1.1329040404040405 prot_standard + coenzyme A + H+ + 2-hydroxyglutarate --> glyoxylate + H2O + propionyl-CoA 0.06604454794825777 +r_4571 seed:rxn00681 1.1329040404040405 prot_standard + coenzyme A + H+ + 2-hydroxyglutarate --> glyoxylate + H2O + propionyl-CoA 0.06654523127145702 r_4571_REV seed:rxn00681 (reversible) 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + 2-hydroxyglutarate 0.0 -r_4572 beta-alanine:2-oxoglutarate aminotransferase 1.1329040404040405 prot_standard + 2-oxoglutarate + beta-alanine --> L-glutamate + 3-oxopropanoate 0.0017781246204641268 +r_4572 beta-alanine:2-oxoglutarate aminotransferase 1.1329040404040405 prot_standard + 2-oxoglutarate + beta-alanine --> L-glutamate + 3-oxopropanoate 0.0017781246203915357 r_4572_REV beta-alanine:2-oxoglutarate aminotransferase (reversible) 1.1329040404040405 prot_standard + L-glutamate + 3-oxopropanoate --> 2-oxoglutarate + beta-alanine 0.0 r_4573 3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NAD + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADH 0.0 -r_4574 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NADP(+) + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADPH 0.0017781246204641268 +r_4574 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 1.1329040404040405 prot_standard + coenzyme A + NADP(+) + 3-oxopropanoate --> acetyl-CoA + carbon dioxide + NADPH 0.0017781246203915357 r_4575 3-oxopropanoate carboxy-lyase 0.45405614353626883 prot_standard + H+ + 3-oxopropanoate --> acetaldehyde + carbon dioxide 0.0 -r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.048490056204063985 prot_standard + NAD + (2R,3S)-3-methylmalate --> 2-oxobutanoate + carbon dioxide + NADH 0.06604454794825777 -r_4582 malate/beta-methylmalate synthase 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + (2R,3S)-3-methylmalate 0.06604454794825777 +r_4581 (2R,3S)-3-methylmalate:NAD+ oxidoreductase 0.048490056204063985 prot_standard + NAD + (2R,3S)-3-methylmalate --> 2-oxobutanoate + carbon dioxide + NADH 0.06604454794825838 +r_4582 malate/beta-methylmalate synthase 1.1329040404040405 prot_standard + glyoxylate + H2O + propionyl-CoA --> coenzyme A + H+ + (2R,3S)-3-methylmalate 0.06604454794825838 r_4583 palmitoyl-CoA hydrolase 2.0068374645606704 prot_standard + H2O + trans-2,cis-9-octadecadienoyl-CoA --> coenzyme A + H+ + (9Z,12Z)-octadecadienoate 0.0 r_4584_EXP_1 long-chain-fatty-acid---CoA ligase 745.8429118773946 prot_P30624 + ATP + coenzyme A + (9Z,12Z)-octadecadienoate --> AMP + diphosphate + trans-2,cis-9-octadecadienoyl-CoA 0.0 r_4584_EXP_2 long-chain-fatty-acid---CoA ligase 799.2145593869732 prot_P39518 + ATP + coenzyme A + (9Z,12Z)-octadecadienoate --> AMP + diphosphate + trans-2,cis-9-octadecadienoyl-CoA 0.0 @@ -6530,11 +6530,11 @@ r_4606 O-phosphoethanolamine transport H+ + O-phosphoethanolamine --> H+ + O-pho r_4606_REV O-phosphoethanolamine transport (reversible) H+ + O-phosphoethanolamine --> H+ + O-phosphoethanolamine 0.0 r_4607 phosphate transport phosphate --> phosphate 0.0 r_4607_REV phosphate transport (reversible) phosphate --> phosphate 0.0 -r_4608 propionyl-CoA transport ATP + H2O + propionyl-CoA --> ADP + H+ + phosphate + propionyl-CoA 0.0 +r_4608 propionyl-CoA transport ATP + H2O + propionyl-CoA --> ADP + H+ + phosphate + propionyl-CoA 0.0005006833231986364 r_4609 UDP transport UDP --> UDP 0.0 r_4609_REV UDP transport (reversible) UDP --> UDP 0.0 r_4610 UDP transport UDP --> UDP 0.0 -r_4610_REV UDP transport (reversible) UDP --> UDP 0.014290109378625914 +r_4610_REV UDP transport (reversible) UDP --> UDP 0.0 r_4611 UMP transport UMP --> UMP 0.0 r_4611_REV UMP transport (reversible) UMP --> UMP 0.0 r_4612 TRX1 disulphide transport TRX1 disulphide --> TRX1 disulphide 0.0 @@ -6621,7 +6621,7 @@ r_4651_EXP_2 pyruvate decarboxylase (aldedyde-forming) 0.11780651340996169 prot_ r_4651_EXP_3 pyruvate decarboxylase (aldedyde-forming) 0.27738351254480287 prot_P16467 + 2-oxobutanoate + H+ --> carbon dioxide + propanal 0.0 r_4652_EXP_1 aldehyde dehydrogenase (1-propanol, NAD) 14.32572298325723 prot_P38113 + H+ + NADH + propanal --> NAD + propanol 0.0 r_4652_EXP_2 aldehyde dehydrogenase (1-propanol, NAD) 15.617199391171994 prot_P32771 + H+ + NADH + propanal --> NAD + propanol 0.0 -r_4652_EXP_3 aldehyde dehydrogenase (1-propanol, NAD) 0.011373148148148148 prot_P00330 + H+ + NADH + propanal --> NAD + propanol 0.0 +r_4652_EXP_3 aldehyde dehydrogenase (1-propanol, NAD) 0.011373148148148148 prot_P00330 + H+ + NADH + propanal --> NAD + propanol 3.922891305596643e-05 r_4653_EXP_1 aldehyde dehydrogenase (1-propanol, NAD) 0.012698148148148148 prot_P10127 + H+ + NADH + propanal --> NAD + propanol 0.0 r_4653_EXP_2 aldehyde dehydrogenase (1-propanol, NAD) 15.361491628614916 prot_P07246 + H+ + NADH + propanal --> NAD + propanol 0.0 r_4654_EXP_1 aldehyde dehydrogenase (1-propanol, NADP) 1.6815384615384616 prot_P25377 + H+ + NADPH + propanal --> NADP(+) + propanol 0.0 @@ -6676,7 +6676,7 @@ r_4678_EXP_1 aldehyde dehydrogenase 0.483596214511041 prot_P47771 + H2O + NAD + r_4678_EXP_2 aldehyde dehydrogenase 0.7809503666102651 prot_P54114 + H2O + NAD + propanal --> H+ + NADH + propionate 0.0 r_4678_EXP_3 aldehyde dehydrogenase 5.830373503190885 prot_P46367 + H2O + NAD + propanal --> H+ + NADH + propionate 0.0 r_4678_REV_EXP_1 aldehyde dehydrogenase (reversible) 0.483596214511041 prot_P47771 + H+ + NADH + propionate --> H2O + NAD + propanal 0.0 -r_4678_REV_EXP_2 aldehyde dehydrogenase (reversible) 0.06410300925925926 prot_P54114 + H+ + NADH + propionate --> H2O + NAD + propanal 0.0 +r_4678_REV_EXP_2 aldehyde dehydrogenase (reversible) 0.06410300925925926 prot_P54114 + H+ + NADH + propionate --> H2O + NAD + propanal 3.922891305596643e-05 r_4678_REV_EXP_3 aldehyde dehydrogenase (reversible) 4.681477254164319 prot_P46367 + H+ + NADH + propionate --> H2O + NAD + propanal 0.0 r_4679_EXP_1 short-chain-fatty-acid-CoA ligase (propionate) 745.8429118773946 prot_P30624 + ATP + coenzyme A + propionate --> AMP + diphosphate + H+ + propionyl-CoA 0.0 r_4679_EXP_2 short-chain-fatty-acid-CoA ligase (propionate) 799.2145593869732 prot_P39518 + ATP + coenzyme A + propionate --> AMP + diphosphate + H+ + propionyl-CoA 0.0 @@ -6685,13 +6685,13 @@ r_4679_EXP_4 short-chain-fatty-acid-CoA ligase (propionate) 740.1053639846743 pr r_4679_REV_EXP_1 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 4.2393447911960855 prot_P30624 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 r_4679_REV_EXP_2 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 85.88964551313514 prot_P39518 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 r_4679_REV_EXP_3 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 57.978811271186636 prot_P39002 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 -r_4679_REV_EXP_4 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 2.7763568922936326 prot_P47912 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 0.0 +r_4679_REV_EXP_4 short-chain-fatty-acid-CoA ligase (propionate) (reversible) 2.7763568922936326 prot_P47912 + AMP + diphosphate + H+ + propionyl-CoA --> ATP + coenzyme A + propionate 3.922891305596643e-05 r_4680_EXP_1 alcohol acyltransferase (propionyl-CoA) 23.194229036950972 prot_P38295 + ethanol + propionyl-CoA --> coenzyme A + ethyl propionate 0.0 r_4680_EXP_2 alcohol acyltransferase (propionyl-CoA) 14.276408471502988 prot_Q02891 + ethanol + propionyl-CoA --> coenzyme A + ethyl propionate 0.0 r_4680_REV_EXP_1 alcohol acyltransferase (propionyl-CoA) (reversible) 2.0370798777168075 prot_P38295 + coenzyme A + ethyl propionate --> ethanol + propionyl-CoA 0.0 r_4680_REV_EXP_2 alcohol acyltransferase (propionyl-CoA) (reversible) 1.7854367520755017 prot_Q02891 + coenzyme A + ethyl propionate --> ethanol + propionyl-CoA 0.0 r_4681 propionyl-CoA transport, mitochondrial propionyl-CoA --> propionyl-CoA 0.0 -r_4681_REV propionyl-CoA transport, mitochondrial (reversible) propionyl-CoA --> propionyl-CoA 0.0 +r_4681_REV propionyl-CoA transport, mitochondrial (reversible) propionyl-CoA --> propionyl-CoA 3.922891305596643e-05 r_4682 butyryl-CoA transport, mitochondrial butanoyl-CoA --> butanoyl-CoA 0.0 r_4682_REV butyryl-CoA transport, mitochondrial (reversible) butanoyl-CoA --> butanoyl-CoA 0.0 r_4683 hexanoyl-CoA transport, mitochondrial hexanoyl-CoA --> hexanoyl-CoA 0.0 @@ -6700,7 +6700,7 @@ r_4684 octanoyl-CoA transport, mitochondrial octanoyl-CoA --> octanoyl-CoA 0.0 r_4684_REV octanoyl-CoA transport, mitochondrial (reversible) octanoyl-CoA --> octanoyl-CoA 0.0 r_4685 decanoyl-CoA transport, mitochondrial decanoyl-CoA --> decanoyl-CoA 0.0 r_4685_REV decanoyl-CoA transport, mitochondrial (reversible) decanoyl-CoA --> decanoyl-CoA 0.0 -r_4686 propionate transport, cytosol propionate --> propionate 0.0 +r_4686 propionate transport, cytosol propionate --> propionate 3.922891305596643e-05 r_4686_REV propionate transport, cytosol (reversible) propionate --> propionate 0.0 r_4687_EXP_1 alcohol acetyltransferase (tyrosol) 0.00442002285061411 prot_P53296 + acetyl-CoA + tyrosol --> coenzyme A + tyrosyl acetate 0.0 r_4687_EXP_2 alcohol acetyltransferase (tyrosol) 0.004358469008854613 prot_P40353 + acetyl-CoA + tyrosol --> coenzyme A + tyrosyl acetate 0.0 @@ -6713,10 +6713,10 @@ r_4690_EXP_3 alcohol acetyltransferase (methionol) 1.451522803795531 prot_P53208 r_4691 methionyl acetate transport methionyl acetate --> methionyl acetate 0.0 r_4692 methionyl acetate exchange methionyl acetate --> 0.0 r_4693_EXP_1 alcohol acetyltransferase (propanol) 0.00442002285061411 prot_P53296 + acetyl-CoA + propanol --> coenzyme A + propyl acetate 0.0 -r_4693_EXP_2 alcohol acetyltransferase (propanol) 0.004358469008854613 prot_P40353 + acetyl-CoA + propanol --> coenzyme A + propyl acetate 0.0 +r_4693_EXP_2 alcohol acetyltransferase (propanol) 0.004358469008854613 prot_P40353 + acetyl-CoA + propanol --> coenzyme A + propyl acetate 3.922891305596643e-05 r_4693_EXP_3 alcohol acetyltransferase (propanol) 1.451522803795531 prot_P53208 + acetyl-CoA + propanol --> coenzyme A + propyl acetate 0.0 -r_4694 propyl acetate transport propyl acetate --> propyl acetate 0.0 -r_4695 propyl acetate exchange propyl acetate --> 0.0 +r_4694 propyl acetate transport propyl acetate --> propyl acetate 3.922891305596643e-05 +r_4695 propyl acetate exchange propyl acetate --> 3.922891305596643e-05 r_4697 ethyl propionate transport, mitochondrial ethyl propionate --> ethyl propionate 0.0 r_4697_REV ethyl propionate transport, mitochondrial (reversible) ethyl propionate --> ethyl propionate 0.0 r_4698_EXP_1 ethyl propionate transport 1.5359391245241716 prot_P53943 + ethyl propionate --> ethyl propionate 0.0 @@ -6741,7 +6741,7 @@ r_4713 diethyl-succinate esterase, c 0.6999026130385602 prot_P41734 + 2.0 H2O + r_4714 monoethyl-succinate esterase, c 1.904471172313294 prot_P41734 + H2O + monoethyl succinate --> ethanol + H+ + succinate 0.0 r_4715 ethyl-benzoate esterase, c 0.6373394427505839 prot_P41734 + ethanol + H+ + Benzoate --> H2O + ethyl benzoate 0.0 r_4715_REV ethyl-benzoate esterase, c (reversible) 0.18097415408676656 prot_P41734 + H2O + ethyl benzoate --> ethanol + H+ + Benzoate 0.0 -r_4716 ethyl-pyruvate esterase, c 0.4678722720909454 prot_P41734 + ethanol + H+ + pyruvate --> H2O + ethyl pyruvate 0.009947311814882828 +r_4716 ethyl-pyruvate esterase, c 0.4678722720909454 prot_P41734 + ethanol + H+ + pyruvate --> H2O + ethyl pyruvate 0.0 r_4716_REV ethyl-pyruvate esterase, c (reversible) 0.9013497163220969 prot_P41734 + H2O + ethyl pyruvate --> ethanol + H+ + pyruvate 0.0 r_4717 benzyl-acetate esterase, c 0.49634581652286863 prot_P41734 + acetate + H+ + benzyl alcohol --> H2O + benzyl acetate 0.0 r_4717_REV benzyl-acetate esterase, c (reversible) 0.2685694933176656 prot_P41734 + H2O + benzyl acetate --> acetate + H+ + benzyl alcohol 0.0 @@ -6760,8 +6760,8 @@ r_4721_REV ethyl-2-methylbutyrate esterase, c (reversible) 0.1481119020744172 pr r_4722 polyphosphate polymerase, c 0.6242867867867868 prot_P47075 + 2.0 ATP + H2O --> 2.0 ADP + H+ + polyphosphate 0.0 r_4723_EXP_1 polyphosphate phosphohydrolase, v 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4723_EXP_2 polyphosphate phosphohydrolase, v 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 -r_4724_EXP_1 polyphosphate phosphohydrolase, m 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 9.054252334287415 -r_4724_EXP_2 polyphosphate phosphohydrolase, m 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 +r_4724_EXP_1 polyphosphate phosphohydrolase, m 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 8.51015040865145 +r_4724_EXP_2 polyphosphate phosphohydrolase, m 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.736137535257238 r_4725_EXP_1 polyphosphate phosphohydrolase, n 0.010881884057971015 prot_P38698 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4725_EXP_2 polyphosphate phosphohydrolase, n 0.018923671497584543 prot_Q04119 + H2O + polyphosphate --> H+ + 2.0 phosphate 0.0 r_4726 ethyl-(2S)-lactate transport ethyl (2S)-lactate --> ethyl (2S)-lactate 0.0 @@ -6779,9 +6779,9 @@ r_4733 monoethyl-succinate exchange monoethyl succinate --> 0.0 r_4734 ethyl-benzoate transport ethyl benzoate --> ethyl benzoate 0.0 r_4734_REV ethyl-benzoate transport (reversible) ethyl benzoate --> ethyl benzoate 0.0 r_4735 ethyl-benzoate exchange ethyl benzoate --> 0.0 -r_4736 ethyl-pyruvate transport ethyl pyruvate --> ethyl pyruvate 0.009947311814882828 +r_4736 ethyl-pyruvate transport ethyl pyruvate --> ethyl pyruvate 0.0 r_4736_REV ethyl-pyruvate transport (reversible) ethyl pyruvate --> ethyl pyruvate 0.0 -r_4737 ethyl-pyruvate exchange ethyl pyruvate --> 0.009947311814882828 +r_4737 ethyl-pyruvate exchange ethyl pyruvate --> 0.0 r_4738 benzyl-acetate transport benzyl acetate --> benzyl acetate 0.0 r_4738_REV benzyl-acetate transport (reversible) benzyl acetate --> benzyl acetate 0.0 r_4739 benzyl-acetate exchange benzyl acetate --> 0.0 @@ -6793,7 +6793,7 @@ r_4742_REV ethyl-2-methylbutyrate transport (reversible) ethyl 2-methylbutyrate r_4743 ethyl-2-methylbutyrate exchange ethyl 2-methylbutyrate --> 0.0 r_4744 polyphosphate transport, v-c H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4744_REV polyphosphate transport, v-c (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 -r_4745 polyphosphate transport, c-m H+ + polyphosphate --> H+ + polyphosphate 9.054252334287414 +r_4745 polyphosphate transport, c-m H+ + polyphosphate --> H+ + polyphosphate 9.246287943908689 r_4745_REV polyphosphate transport, c-m (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4746 polyphosphate transport, c-n H+ + polyphosphate --> H+ + polyphosphate 0.0 r_4746_REV polyphosphate transport, c-n (reversible) H+ + polyphosphate --> H+ + polyphosphate 0.0 @@ -6802,7 +6802,7 @@ r_4747_EXP_2 cytidine kinase (ATP) 1.7180232558139534 prot_Q12084 + ATP + cytidi r_4748_EXP_1 D-glyceraldehyde kinase 0.719388935146637 prot_P54838 + ATP + D-glyceraldehyde --> ADP + glyceraldehyde 3-phosphate + H+ 0.0 r_4748_EXP_2 D-glyceraldehyde kinase 0.7185562956795263 prot_P43550 + ATP + D-glyceraldehyde --> ADP + glyceraldehyde 3-phosphate + H+ 0.0 r_4749 adenosine phosphorylase 0.0027177938808373592 prot_Q05788 + adenosine + phosphate --> adenine + alpha-D-ribose 1-phosphate(2-) 0.0 -r_4749_REV adenosine phosphorylase (reversible) 0.21358516831181978 prot_Q05788 + adenine + alpha-D-ribose 1-phosphate(2-) --> adenosine + phosphate 0.0018332246222373496 +r_4749_REV adenosine phosphorylase (reversible) 0.21358516831181978 prot_Q05788 + adenine + alpha-D-ribose 1-phosphate(2-) --> adenosine + phosphate 0.001833224622164148 r_4750 D-glucose 1-epimerase 0.532373366013072 prot_P04397 + alpha-D-Glucose --> beta-D-Glucose 0.0 r_4750_REV D-glucose 1-epimerase (reversible) 0.532373366013072 prot_P04397 + beta-D-Glucose --> alpha-D-Glucose 0.0 r_4751_EXP_1 D-phenylalanine N-acetyltransferase 2.211905943882526 prot_P39979 + acetyl-CoA + D-phenylalanine --> coenzyme A + N-acetyl-D-phenylalanine 0.0 @@ -6865,56 +6865,56 @@ r_4787_EXP_2 ribonucleotide reductase 0.862510766580534 prot_P49723 + H+ + UDP + r_4787_EXP_3 ribonucleotide reductase 2.0998062015503876 prot_P21672 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 r_4787_EXP_4 ribonucleotide reductase 0.9936907838070629 prot_P09938 + H+ + UDP + TRX1 --> dUDP + H2O + TRX1 disulphide 0.0 usage_prot_O13525 usage_prot_O13525 prot_pool --> prot_O13525 0.0 -usage_prot_P00044 usage_prot_P00044 prot_pool --> prot_P00044 0.16847634416118706 -usage_prot_P00045 usage_prot_P00045 prot_pool --> prot_P00045 0.05777631006199014 -usage_prot_P00127 usage_prot_P00127 prot_pool --> prot_P00127 0.2641879925343842 -usage_prot_P00128 usage_prot_P00128 prot_pool --> prot_P00128 0.2229760741301098 -usage_prot_P00163 usage_prot_P00163 prot_pool --> prot_P00163 0.6683311700806093 +usage_prot_P00044 usage_prot_P00044 prot_pool --> prot_P00044 0.06548679829397339 +usage_prot_P00045 usage_prot_P00045 prot_pool --> prot_P00045 0.0 +usage_prot_P00127 usage_prot_P00127 prot_pool --> prot_P00127 0.04893340827086535 +usage_prot_P00128 usage_prot_P00128 prot_pool --> prot_P00128 0.041300057452926565 +usage_prot_P00163 usage_prot_P00163 prot_pool --> prot_P00163 0.12378958518125385 usage_prot_P00175 usage_prot_P00175 prot_pool --> prot_P00175 0.0 -usage_prot_P00330 usage_prot_P00330 prot_pool --> prot_P00330 0.038622400641181526 +usage_prot_P00330 usage_prot_P00330 prot_pool --> prot_P00330 0.04304624297783312 usage_prot_P00331 usage_prot_P00331 prot_pool --> prot_P00331 0.0 -usage_prot_P00358 usage_prot_P00358 prot_pool --> prot_P00358 4.996923642027722 +usage_prot_P00358 usage_prot_P00358 prot_pool --> prot_P00358 5.016088627525685 usage_prot_P00359 usage_prot_P00359 prot_pool --> prot_P00359 0.0 usage_prot_P00360 usage_prot_P00360 prot_pool --> prot_P00360 0.2252629206352891 -usage_prot_P00401 usage_prot_P00401 prot_pool --> prot_P00401 0.37997077999169726 -usage_prot_P00410 usage_prot_P00410 prot_pool --> prot_P00410 0.18460874982181052 -usage_prot_P00420 usage_prot_P00420 prot_pool --> prot_P00420 0.19619566788917872 -usage_prot_P00424 usage_prot_P00424 prot_pool --> prot_P00424 0.053668940876738964 +usage_prot_P00401 usage_prot_P00401 prot_pool --> prot_P00401 0.14935474369963514 +usage_prot_P00410 usage_prot_P00410 prot_pool --> prot_P00410 0.07256398114336333 +usage_prot_P00420 usage_prot_P00420 prot_pool --> prot_P00420 0.07711843972109464 +usage_prot_P00424 usage_prot_P00424 prot_pool --> prot_P00424 0.043537880659405864 usage_prot_P00425 usage_prot_P00425 prot_pool --> prot_P00425 0.0 -usage_prot_P00427 usage_prot_P00427 prot_pool --> prot_P00427 0.05430144531414277 +usage_prot_P00427 usage_prot_P00427 prot_pool --> prot_P00427 0.04405098753765558 usage_prot_P00431 usage_prot_P00431 prot_pool --> prot_P00431 0.0 usage_prot_P00445 usage_prot_P00445 prot_pool --> prot_P00445 0.0 usage_prot_P00447 usage_prot_P00447 prot_pool --> prot_P00447 0.0 usage_prot_P00498 usage_prot_P00498 prot_pool --> prot_P00498 0.020111855410778503 -usage_prot_P00549 usage_prot_P00549 prot_pool --> prot_P00549 0.621909919233911 -usage_prot_P00560 usage_prot_P00560 prot_pool --> prot_P00560 0.2308695568133533 +usage_prot_P00549 usage_prot_P00549 prot_pool --> prot_P00549 0.624009048151248 +usage_prot_P00560 usage_prot_P00560 prot_pool --> prot_P00560 0.2316138038603722 usage_prot_P00572 usage_prot_P00572 prot_pool --> prot_P00572 0.0 usage_prot_P00635 usage_prot_P00635 prot_pool --> prot_P00635 0.0 usage_prot_P00724 usage_prot_P00724 prot_pool --> prot_P00724 0.0 usage_prot_P00812 usage_prot_P00812 prot_pool --> prot_P00812 0.0 usage_prot_P00815 usage_prot_P00815 prot_pool --> prot_P00815 0.1770687166136681 -usage_prot_P00817 usage_prot_P00817 prot_pool --> prot_P00817 0.09757993353329403 -usage_prot_P00830 usage_prot_P00830 prot_pool --> prot_P00830 10.536597985467331 -usage_prot_P00854 usage_prot_P00854 prot_pool --> prot_P00854 1.8651948800909701 -usage_prot_P00856 usage_prot_P00856 prot_pool --> prot_P00856 0.37317999216088626 -usage_prot_P00890 usage_prot_P00890 prot_pool --> prot_P00890 0.26245166779057216 -usage_prot_P00899 usage_prot_P00899 prot_pool --> prot_P00899 0.0014792527493025826 -usage_prot_P00912 usage_prot_P00912 prot_pool --> prot_P00912 0.0012708648944102696 -usage_prot_P00924 usage_prot_P00924 prot_pool --> prot_P00924 0.5493975455867349 +usage_prot_P00817 usage_prot_P00817 prot_pool --> prot_P00817 0.11137863224597393 +usage_prot_P00830 usage_prot_P00830 prot_pool --> prot_P00830 0.514069744030003 +usage_prot_P00854 usage_prot_P00854 prot_pool --> prot_P00854 0.09100093368817182 +usage_prot_P00856 usage_prot_P00856 prot_pool --> prot_P00856 0.0182070667697356 +usage_prot_P00890 usage_prot_P00890 prot_pool --> prot_P00890 0.24072631529247424 +usage_prot_P00899 usage_prot_P00899 prot_pool --> prot_P00899 0.0014792527493022903 +usage_prot_P00912 usage_prot_P00912 prot_pool --> prot_P00912 0.0012708648944103214 +usage_prot_P00924 usage_prot_P00924 prot_pool --> prot_P00924 0.5512148957682297 usage_prot_P00925 usage_prot_P00925 prot_pool --> prot_P00925 0.0 usage_prot_P00927 usage_prot_P00927 prot_pool --> prot_P00927 0.0 -usage_prot_P00931 usage_prot_P00931 prot_pool --> prot_P00931 0.005644290525627469 -usage_prot_P00937 usage_prot_P00937 prot_pool --> prot_P00937 0.021663525788062077 -usage_prot_P00942 usage_prot_P00942 prot_pool --> prot_P00942 0.004287165183541316 -usage_prot_P00950 usage_prot_P00950 prot_pool --> prot_P00950 0.1293744271420724 +usage_prot_P00931 usage_prot_P00931 prot_pool --> prot_P00931 0.005644290525627699 +usage_prot_P00937 usage_prot_P00937 prot_pool --> prot_P00937 0.02166352578806263 +usage_prot_P00942 usage_prot_P00942 prot_pool --> prot_P00942 0.00431478257552091 +usage_prot_P00950 usage_prot_P00950 prot_pool --> prot_P00950 0.12980238434817226 usage_prot_P00958 usage_prot_P00958 prot_pool --> prot_P00958 0.02249929533789948 -usage_prot_P03962 usage_prot_P03962 prot_pool --> prot_P03962 0.00044327123936740965 +usage_prot_P03962 usage_prot_P03962 prot_pool --> prot_P03962 0.00044327123936740997 usage_prot_P03965 usage_prot_P03965 prot_pool --> prot_P03965 0.0 -usage_prot_P04037 usage_prot_P04037 prot_pool --> prot_P04037 0.05367833450699744 -usage_prot_P04039 usage_prot_P04039 prot_pool --> prot_P04039 0.02788968823740455 -usage_prot_P04046 usage_prot_P04046 prot_pool --> prot_P04046 0.008415255585641358 +usage_prot_P04037 usage_prot_P04037 prot_pool --> prot_P04037 0.043545501058587795 +usage_prot_P04039 usage_prot_P04039 prot_pool --> prot_P04039 0.02262496517113933 +usage_prot_P04046 usage_prot_P04046 prot_pool --> prot_P04046 0.0084152555856404 usage_prot_P04076 usage_prot_P04076 prot_pool --> prot_P04076 0.00027771776350733187 -usage_prot_P04161 usage_prot_P04161 prot_pool --> prot_P04161 0.00485467324733399 +usage_prot_P04161 usage_prot_P04161 prot_pool --> prot_P04161 0.004854673247333438 usage_prot_P04173 usage_prot_P04173 prot_pool --> prot_P04173 0.006978863773044375 usage_prot_P04385 usage_prot_P04385 prot_pool --> prot_P04385 0.0 usage_prot_P04397 usage_prot_P04397 prot_pool --> prot_P04397 0.0 @@ -6929,17 +6929,17 @@ usage_prot_P05030 usage_prot_P05030 prot_pool --> prot_P05030 0.0 usage_prot_P05150 usage_prot_P05150 prot_pool --> prot_P05150 0.0001742165495789804 usage_prot_P05316 usage_prot_P05316 prot_pool --> prot_P05316 0.0 usage_prot_P05373 usage_prot_P05373 prot_pool --> prot_P05373 2.3125213759543194e-06 -usage_prot_P05374 usage_prot_P05374 prot_pool --> prot_P05374 1.7061095325235494 -usage_prot_P05375 usage_prot_P05375 prot_pool --> prot_P05375 0.024738604156327608 -usage_prot_P05626 usage_prot_P05626 prot_pool --> prot_P05626 1.7258452918124116 -usage_prot_P05694 usage_prot_P05694 prot_pool --> prot_P05694 1.563480444634272 -usage_prot_P06106 usage_prot_P06106 prot_pool --> prot_P06106 0.004837531563630091 -usage_prot_P06115 usage_prot_P06115 prot_pool --> prot_P06115 5.810519521886276e-09 -usage_prot_P06168 usage_prot_P06168 prot_pool --> prot_P06168 0.18413552912212144 -usage_prot_P06169 usage_prot_P06169 prot_pool --> prot_P06169 0.5902347624676731 +usage_prot_P05374 usage_prot_P05374 prot_pool --> prot_P05374 1.706109532523549 +usage_prot_P05375 usage_prot_P05375 prot_pool --> prot_P05375 0.024738604156327604 +usage_prot_P05626 usage_prot_P05626 prot_pool --> prot_P05626 0.08420221105721935 +usage_prot_P05694 usage_prot_P05694 prot_pool --> prot_P05694 1.5634804446342716 +usage_prot_P06106 usage_prot_P06106 prot_pool --> prot_P06106 0.004837531563630006 +usage_prot_P06115 usage_prot_P06115 prot_pool --> prot_P06115 5.810519521654258e-09 +usage_prot_P06168 usage_prot_P06168 prot_pool --> prot_P06168 0.18413552912292963 +usage_prot_P06169 usage_prot_P06169 prot_pool --> prot_P06169 0.490233696674406 usage_prot_P06174 usage_prot_P06174 prot_pool --> prot_P06174 2.7979026146588213e-09 usage_prot_P06182 usage_prot_P06182 prot_pool --> prot_P06182 0.0 -usage_prot_P06197 usage_prot_P06197 prot_pool --> prot_P06197 0.0025205897491593103 +usage_prot_P06197 usage_prot_P06197 prot_pool --> prot_P06197 0.002520589749159676 usage_prot_P06208 usage_prot_P06208 prot_pool --> prot_P06208 0.10845344114423203 usage_prot_P06633 usage_prot_P06633 prot_pool --> prot_P06633 0.0001145991618788222 usage_prot_P06700 usage_prot_P06700 prot_pool --> prot_P06700 0.0 @@ -6949,31 +6949,31 @@ usage_prot_P06775 usage_prot_P06775 prot_pool --> prot_P06775 0.0006006170410858 usage_prot_P06776 usage_prot_P06776 prot_pool --> prot_P06776 0.0 usage_prot_P06780 usage_prot_P06780 prot_pool --> prot_P06780 0.26514554729637085 usage_prot_P06785 usage_prot_P06785 prot_pool --> prot_P06785 0.00021174228802941519 -usage_prot_P07143 usage_prot_P07143 prot_pool --> prot_P07143 0.5213491386543694 +usage_prot_P07143 usage_prot_P07143 prot_pool --> prot_P07143 0.09656529052931098 usage_prot_P07149 usage_prot_P07149 prot_pool --> prot_P07149 1.4876173928641878 -usage_prot_P07170 usage_prot_P07170 prot_pool --> prot_P07170 0.01507810773366886 +usage_prot_P07170 usage_prot_P07170 prot_pool --> prot_P07170 0.01814130095989918 usage_prot_P07172 usage_prot_P07172 prot_pool --> prot_P07172 9.2607758562984e-05 usage_prot_P07236 usage_prot_P07236 prot_pool --> prot_P07236 0.0 -usage_prot_P07244 usage_prot_P07244 prot_pool --> prot_P07244 0.20285569464815725 -usage_prot_P07245 usage_prot_P07245 prot_pool --> prot_P07245 0.09914881834076184 +usage_prot_P07244 usage_prot_P07244 prot_pool --> prot_P07244 0.2028556946481342 +usage_prot_P07245 usage_prot_P07245 prot_pool --> prot_P07245 0.09914881834080592 usage_prot_P07246 usage_prot_P07246 prot_pool --> prot_P07246 0.0 usage_prot_P07250 usage_prot_P07250 prot_pool --> prot_P07250 0.0 -usage_prot_P07251 usage_prot_P07251 prot_pool --> prot_P07251 11.270010123960093 -usage_prot_P07255 usage_prot_P07255 prot_pool --> prot_P07255 0.04499704991806164 -usage_prot_P07256 usage_prot_P07256 prot_pool --> prot_P07256 0.7689421387852493 -usage_prot_P07257 usage_prot_P07257 prot_pool --> prot_P07257 0.6196790613552068 +usage_prot_P07251 usage_prot_P07251 prot_pool --> prot_P07251 0.5498521655310877 +usage_prot_P07255 usage_prot_P07255 prot_pool --> prot_P07255 0.017686946501251053 +usage_prot_P07256 usage_prot_P07256 prot_pool --> prot_P07256 0.14242494237868833 +usage_prot_P07257 usage_prot_P07257 prot_pool --> prot_P07257 0.11477814799722359 usage_prot_P07258 usage_prot_P07258 prot_pool --> prot_P07258 0.0 -usage_prot_P07259 usage_prot_P07259 prot_pool --> prot_P07259 0.006030317198174186 -usage_prot_P07262 usage_prot_P07262 prot_pool --> prot_P07262 0.849514101794851 +usage_prot_P07259 usage_prot_P07259 prot_pool --> prot_P07259 0.00603031719817419 +usage_prot_P07262 usage_prot_P07262 prot_pool --> prot_P07262 0.8495141017948682 usage_prot_P07263 usage_prot_P07263 prot_pool --> prot_P07263 0.010089779898637853 usage_prot_P07264 usage_prot_P07264 prot_pool --> prot_P07264 0.16157271173565627 usage_prot_P07275 usage_prot_P07275 prot_pool --> prot_P07275 0.0 -usage_prot_P07277 usage_prot_P07277 prot_pool --> prot_P07277 0.03030762198090301 +usage_prot_P07277 usage_prot_P07277 prot_pool --> prot_P07277 0.030307621980903015 usage_prot_P07283 usage_prot_P07283 prot_pool --> prot_P07283 0.08143881881589675 usage_prot_P07284 usage_prot_P07284 prot_pool --> prot_P07284 0.3016596848897915 -usage_prot_P07285 usage_prot_P07285 prot_pool --> prot_P07285 0.03735583357525305 +usage_prot_P07285 usage_prot_P07285 prot_pool --> prot_P07285 0.03735583357525457 usage_prot_P07286 usage_prot_P07286 prot_pool --> prot_P07286 0.0 -usage_prot_P07342 usage_prot_P07342 prot_pool --> prot_P07342 0.019027313534118552 +usage_prot_P07342 usage_prot_P07342 prot_pool --> prot_P07342 0.01902731353421575 usage_prot_P07347 usage_prot_P07347 prot_pool --> prot_P07347 0.0 usage_prot_P07702 usage_prot_P07702 prot_pool --> prot_P07702 0.0988513574502048 usage_prot_P07806 usage_prot_P07806 prot_pool --> prot_P07806 0.06374814514057446 @@ -6981,31 +6981,31 @@ usage_prot_P07807 usage_prot_P07807 prot_pool --> prot_P07807 3.284218441491389e usage_prot_P07991 usage_prot_P07991 prot_pool --> prot_P07991 0.012206868565109486 usage_prot_P08004 usage_prot_P08004 prot_pool --> prot_P08004 0.0 usage_prot_P08019 usage_prot_P08019 prot_pool --> prot_P08019 0.0 -usage_prot_P08067 usage_prot_P08067 prot_pool --> prot_P08067 0.3576955696567124 -usage_prot_P08417 usage_prot_P08417 prot_pool --> prot_P08417 0.031825562788962536 +usage_prot_P08067 usage_prot_P08067 prot_pool --> prot_P08067 0.06625306161260756 +usage_prot_P08417 usage_prot_P08417 prot_pool --> prot_P08417 0.028870581828395858 usage_prot_P08425 usage_prot_P08425 prot_pool --> prot_P08425 0.0 usage_prot_P08431 usage_prot_P08431 prot_pool --> prot_P08431 0.0 usage_prot_P08432 usage_prot_P08432 prot_pool --> prot_P08432 0.0 -usage_prot_P08456 usage_prot_P08456 prot_pool --> prot_P08456 0.21097203462824937 -usage_prot_P08465 usage_prot_P08465 prot_pool --> prot_P08465 0.03391138008614558 +usage_prot_P08456 usage_prot_P08456 prot_pool --> prot_P08456 0.21097203462828235 +usage_prot_P08465 usage_prot_P08465 prot_pool --> prot_P08465 0.033911380086144985 usage_prot_P08524 usage_prot_P08524 prot_pool --> prot_P08524 0.4373227357596712 -usage_prot_P08525 usage_prot_P08525 prot_pool --> prot_P08525 0.168016643568689 -usage_prot_P08536 usage_prot_P08536 prot_pool --> prot_P08536 0.02272610261161025 -usage_prot_P08566 usage_prot_P08566 prot_pool --> prot_P08566 0.19860889691764338 +usage_prot_P08525 usage_prot_P08525 prot_pool --> prot_P08525 0.031120365983238522 +usage_prot_P08536 usage_prot_P08536 prot_pool --> prot_P08536 0.02272610261160985 +usage_prot_P08566 usage_prot_P08566 prot_pool --> prot_P08566 0.1986088969176381 usage_prot_P08678 usage_prot_P08678 prot_pool --> prot_P08678 0.0 usage_prot_P08679 usage_prot_P08679 prot_pool --> prot_P08679 0.0 usage_prot_P09201 usage_prot_P09201 prot_pool --> prot_P09201 0.0 usage_prot_P09368 usage_prot_P09368 prot_pool --> prot_P09368 0.0 usage_prot_P09436 usage_prot_P09436 prot_pool --> prot_P09436 0.03271423384994398 usage_prot_P09440 usage_prot_P09440 prot_pool --> prot_P09440 0.0 -usage_prot_P09457 usage_prot_P09457 prot_pool --> prot_P09457 1.462337399718045 -usage_prot_P09624 usage_prot_P09624 prot_pool --> prot_P09624 0.300872934472309 +usage_prot_P09457 usage_prot_P09457 prot_pool --> prot_P09457 0.07134593288985709 +usage_prot_P09624 usage_prot_P09624 prot_pool --> prot_P09624 0.6377941773486209 usage_prot_P09938 usage_prot_P09938 prot_pool --> prot_P09938 0.0 usage_prot_P09950 usage_prot_P09950 prot_pool --> prot_P09950 1.9924745320065227e-07 usage_prot_P0C5R9 usage_prot_P0C5R9 prot_pool --> prot_P0C5R9 0.0 -usage_prot_P0CD90 usage_prot_P0CD90 prot_pool --> prot_P0CD90 5.706405759784486 +usage_prot_P0CD90 usage_prot_P0CD90 prot_pool --> prot_P0CD90 5.5125895052852725 usage_prot_P0CD91 usage_prot_P0CD91 prot_pool --> prot_P0CD91 0.0 -usage_prot_P0CD98 usage_prot_P0CD98 prot_pool --> prot_P0CD98 0.00418414578789734 +usage_prot_P0CD98 usage_prot_P0CD98 prot_pool --> prot_P0CD98 0.004184145787897345 usage_prot_P0CD99 usage_prot_P0CD99 prot_pool --> prot_P0CD99 0.0 usage_prot_P0CE00 usage_prot_P0CE00 prot_pool --> prot_P0CE00 0.0 usage_prot_P0CH63 usage_prot_P0CH63 prot_pool --> prot_P0CH63 0.0 @@ -7021,141 +7021,141 @@ usage_prot_P0CX78 usage_prot_P0CX78 prot_pool --> prot_P0CX78 0.0 usage_prot_P0CX79 usage_prot_P0CX79 prot_pool --> prot_P0CX79 0.0 usage_prot_P0CZ17 usage_prot_P0CZ17 prot_pool --> prot_P0CZ17 0.0 usage_prot_P10127 usage_prot_P10127 prot_pool --> prot_P10127 0.0 -usage_prot_P10174 usage_prot_P10174 prot_pool --> prot_P10174 0.021705548317243552 +usage_prot_P10174 usage_prot_P10174 prot_pool --> prot_P10174 0.01760820237637115 usage_prot_P10356 usage_prot_P10356 prot_pool --> prot_P10356 0.0 usage_prot_P10566 usage_prot_P10566 prot_pool --> prot_P10566 0.0 usage_prot_P10614 usage_prot_P10614 prot_pool --> prot_P10614 0.02705697218755369 usage_prot_P10659 usage_prot_P10659 prot_pool --> prot_P10659 0.0 -usage_prot_P10869 usage_prot_P10869 prot_pool --> prot_P10869 0.0073086969604796975 +usage_prot_P10869 usage_prot_P10869 prot_pool --> prot_P10869 0.007308696960479654 usage_prot_P10963 usage_prot_P10963 prot_pool --> prot_P10963 0.0 usage_prot_P11154 usage_prot_P11154 prot_pool --> prot_P11154 0.5788507619015835 usage_prot_P11325 usage_prot_P11325 prot_pool --> prot_P11325 0.0 usage_prot_P11353 usage_prot_P11353 prot_pool --> prot_P11353 0.00017870065314359548 -usage_prot_P11412 usage_prot_P11412 prot_pool --> prot_P11412 0.004323417168245322 +usage_prot_P11412 usage_prot_P11412 prot_pool --> prot_P11412 0.0018886305159734038 usage_prot_P11491 usage_prot_P11491 prot_pool --> prot_P11491 1.1572939795485587e-05 -usage_prot_P11986 usage_prot_P11986 prot_pool --> prot_P11986 0.00413147668973789 +usage_prot_P11986 usage_prot_P11986 prot_pool --> prot_P11986 0.0041314766897378695 usage_prot_P12683 usage_prot_P12683 prot_pool --> prot_P12683 0.0596344142062684 -usage_prot_P12684 usage_prot_P12684 prot_pool 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usage_prot_P31115 prot_pool --> prot_P31115 0.0 -usage_prot_P31116 usage_prot_P31116 prot_pool --> prot_P31116 0.04868265878153599 -usage_prot_P31373 usage_prot_P31373 prot_pool --> prot_P31373 0.07147555393367756 +usage_prot_P31116 usage_prot_P31116 prot_pool --> prot_P31116 0.0486826587815357 +usage_prot_P31373 usage_prot_P31373 prot_pool --> prot_P31373 0.07147555393367358 usage_prot_P31381 usage_prot_P31381 prot_pool --> prot_P31381 0.0 usage_prot_P31382 usage_prot_P31382 prot_pool --> prot_P31382 0.0 usage_prot_P31412 usage_prot_P31412 prot_pool --> prot_P31412 0.0 @@ -7231,18 +7231,18 @@ usage_prot_P31688 usage_prot_P31688 prot_pool --> prot_P31688 0.0708633625192050 usage_prot_P31755 usage_prot_P31755 prot_pool --> prot_P31755 0.0 usage_prot_P32048 usage_prot_P32048 prot_pool --> prot_P32048 0.0 usage_prot_P32178 usage_prot_P32178 prot_pool --> prot_P32178 0.0019238103043686396 -usage_prot_P32179 usage_prot_P32179 prot_pool --> prot_P32179 0.03418840468343334 +usage_prot_P32179 usage_prot_P32179 prot_pool --> prot_P32179 0.03462604633377049 usage_prot_P32190 usage_prot_P32190 prot_pool --> prot_P32190 0.0 -usage_prot_P32191 usage_prot_P32191 prot_pool --> prot_P32191 0.0 +usage_prot_P32191 usage_prot_P32191 prot_pool --> prot_P32191 1.7511519410808318e-06 usage_prot_P32263 usage_prot_P32263 prot_pool --> prot_P32263 0.0001091199689856241 usage_prot_P32264 usage_prot_P32264 prot_pool --> prot_P32264 0.018532011528914486 -usage_prot_P32288 usage_prot_P32288 prot_pool --> prot_P32288 0.008878083094174078 -usage_prot_P32316 usage_prot_P32316 prot_pool --> prot_P32316 4.2984556895310675 +usage_prot_P32288 usage_prot_P32288 prot_pool --> prot_P32288 0.008878083094173901 +usage_prot_P32316 usage_prot_P32316 prot_pool --> prot_P32316 0.8125186921989169 usage_prot_P32318 usage_prot_P32318 prot_pool --> prot_P32318 7.105579703422328e-08 -usage_prot_P32327 usage_prot_P32327 prot_pool --> prot_P32327 0.2807522461746592 -usage_prot_P32331 usage_prot_P32331 prot_pool --> prot_P32331 0.00043764932575339813 +usage_prot_P32327 usage_prot_P32327 prot_pool --> prot_P32327 0.13955991117285518 +usage_prot_P32331 usage_prot_P32331 prot_pool --> prot_P32331 0.00043764932574833485 usage_prot_P32332 usage_prot_P32332 prot_pool --> prot_P32332 0.0 -usage_prot_P32340 usage_prot_P32340 prot_pool --> prot_P32340 0.23276367184123004 +usage_prot_P32340 usage_prot_P32340 prot_pool --> prot_P32340 0.21298375931471047 usage_prot_P32347 usage_prot_P32347 prot_pool --> prot_P32347 7.94823011291778e-07 usage_prot_P32352 usage_prot_P32352 prot_pool --> prot_P32352 0.0 usage_prot_P32353 usage_prot_P32353 prot_pool --> prot_P32353 0.0 @@ -7256,7 +7256,7 @@ usage_prot_P32378 usage_prot_P32378 prot_pool --> prot_P32378 0.0 usage_prot_P32383 usage_prot_P32383 prot_pool --> prot_P32383 0.0 usage_prot_P32386 usage_prot_P32386 prot_pool --> prot_P32386 0.0 usage_prot_P32419 usage_prot_P32419 prot_pool --> prot_P32419 0.0 -usage_prot_P32449 usage_prot_P32449 prot_pool --> prot_P32449 0.008779913486203283 +usage_prot_P32449 usage_prot_P32449 prot_pool --> prot_P32449 0.008779913486203052 usage_prot_P32451 usage_prot_P32451 prot_pool --> prot_P32451 0.0 usage_prot_P32452 usage_prot_P32452 prot_pool --> prot_P32452 0.0006256598089209894 usage_prot_P32459 usage_prot_P32459 prot_pool --> prot_P32459 0.0 @@ -7266,7 +7266,7 @@ usage_prot_P32465 usage_prot_P32465 prot_pool --> prot_P32465 0.0 usage_prot_P32466 usage_prot_P32466 prot_pool --> prot_P32466 7.619558160691372 usage_prot_P32467 usage_prot_P32467 prot_pool --> prot_P32467 0.0 usage_prot_P32469 usage_prot_P32469 prot_pool --> prot_P32469 0.0 -usage_prot_P32473 usage_prot_P32473 prot_pool --> prot_P32473 0.17574379068963686 +usage_prot_P32473 usage_prot_P32473 prot_pool --> prot_P32473 0.7022173706499554 usage_prot_P32476 usage_prot_P32476 prot_pool --> prot_P32476 1.7235989743189126 usage_prot_P32477 usage_prot_P32477 prot_pool --> prot_P32477 6.186255588267364e-10 usage_prot_P32486 usage_prot_P32486 prot_pool --> prot_P32486 0.0 @@ -7276,47 +7276,47 @@ usage_prot_P32563 usage_prot_P32563 prot_pool --> prot_P32563 0.0 usage_prot_P32567 usage_prot_P32567 prot_pool --> prot_P32567 0.0 usage_prot_P32573 usage_prot_P32573 prot_pool --> prot_P32573 0.0 usage_prot_P32579 usage_prot_P32579 prot_pool --> prot_P32579 0.0 -usage_prot_P32582 usage_prot_P32582 prot_pool --> prot_P32582 0.007923888407161184 +usage_prot_P32582 usage_prot_P32582 prot_pool --> prot_P32582 0.007923888407160741 usage_prot_P32603 usage_prot_P32603 prot_pool --> prot_P32603 0.0 usage_prot_P32604 usage_prot_P32604 prot_pool --> prot_P32604 0.0 usage_prot_P32610 usage_prot_P32610 prot_pool --> prot_P32610 0.0 -usage_prot_P32614 usage_prot_P32614 prot_pool --> prot_P32614 0.0 +usage_prot_P32614 usage_prot_P32614 prot_pool --> prot_P32614 2.659588677401881e-06 usage_prot_P32621 usage_prot_P32621 prot_pool --> prot_P32621 0.0 usage_prot_P32622 usage_prot_P32622 prot_pool --> prot_P32622 0.0 -usage_prot_P32626 usage_prot_P32626 prot_pool --> prot_P32626 2.5651904755717847e-05 +usage_prot_P32626 usage_prot_P32626 prot_pool --> prot_P32626 2.565190475469355e-05 usage_prot_P32642 usage_prot_P32642 prot_pool --> prot_P32642 0.0 usage_prot_P32643 usage_prot_P32643 prot_pool --> prot_P32643 0.0 usage_prot_P32656 usage_prot_P32656 prot_pool --> prot_P32656 0.0 usage_prot_P32771 usage_prot_P32771 prot_pool --> prot_P32771 0.0 -usage_prot_P32784 usage_prot_P32784 prot_pool --> prot_P32784 2.187673029017438 +usage_prot_P32784 usage_prot_P32784 prot_pool --> prot_P32784 2.187673029017655 usage_prot_P32785 usage_prot_P32785 prot_pool --> prot_P32785 0.0 usage_prot_P32791 usage_prot_P32791 prot_pool --> prot_P32791 0.0 usage_prot_P32796 usage_prot_P32796 prot_pool --> prot_P32796 0.0 usage_prot_P32798 usage_prot_P32798 prot_pool --> prot_P32798 0.0 -usage_prot_P32799 usage_prot_P32799 prot_pool --> prot_P32799 0.0470339067041713 +usage_prot_P32799 usage_prot_P32799 prot_pool --> prot_P32799 0.03815533870390522 usage_prot_P32804 usage_prot_P32804 prot_pool --> prot_P32804 0.0002277769529033155 usage_prot_P32837 usage_prot_P32837 prot_pool --> prot_P32837 0.0 usage_prot_P32842 usage_prot_P32842 prot_pool --> prot_P32842 0.0 usage_prot_P32861 usage_prot_P32861 prot_pool --> prot_P32861 0.0 usage_prot_P32874 usage_prot_P32874 prot_pool --> prot_P32874 0.0 usage_prot_P32891 usage_prot_P32891 prot_pool --> prot_P32891 0.0 -usage_prot_P32895 usage_prot_P32895 prot_pool --> prot_P32895 0.01563149237509729 +usage_prot_P32895 usage_prot_P32895 prot_pool --> prot_P32895 0.01563149237509645 usage_prot_P32901 usage_prot_P32901 prot_pool --> prot_P32901 0.0 usage_prot_P32903 usage_prot_P32903 prot_pool --> prot_P32903 0.0 usage_prot_P32906 usage_prot_P32906 prot_pool --> prot_P32906 0.0 usage_prot_P33300 usage_prot_P33300 prot_pool --> prot_P33300 0.0 -usage_prot_P33303 usage_prot_P33303 prot_pool --> prot_P33303 0.018277678612804424 -usage_prot_P33312 usage_prot_P33312 prot_pool --> prot_P33312 0.00015403813171193444 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prot_pool --> prot_P33421 0.04547772008893361 usage_prot_P33550 usage_prot_P33550 prot_pool --> prot_P33550 0.0 usage_prot_P33734 usage_prot_P33734 prot_pool --> prot_P33734 0.059579296424713026 usage_prot_P33751 usage_prot_P33751 prot_pool --> prot_P33751 0.0 @@ -7335,54 +7335,54 @@ usage_prot_P35731 usage_prot_P35731 prot_pool --> prot_P35731 0.0 usage_prot_P35842 usage_prot_P35842 prot_pool --> prot_P35842 0.0 usage_prot_P36001 usage_prot_P36001 prot_pool --> prot_P36001 0.0 usage_prot_P36007 usage_prot_P36007 prot_pool --> prot_P36007 0.0 -usage_prot_P36010 usage_prot_P36010 prot_pool --> prot_P36010 0.010513130910886242 -usage_prot_P36013 usage_prot_P36013 prot_pool --> prot_P36013 0.029253903110523546 +usage_prot_P36010 usage_prot_P36010 prot_pool --> prot_P36010 0.010513130910886183 +usage_prot_P36013 usage_prot_P36013 prot_pool --> prot_P36013 0.029253903110709075 usage_prot_P36014 usage_prot_P36014 prot_pool --> prot_P36014 0.0 -usage_prot_P36024 usage_prot_P36024 prot_pool --> prot_P36024 0.0003297450106118214 +usage_prot_P36024 usage_prot_P36024 prot_pool --> prot_P36024 0.00032974501060816717 usage_prot_P36029 usage_prot_P36029 prot_pool --> prot_P36029 0.0 usage_prot_P36033 usage_prot_P36033 prot_pool --> prot_P36033 0.0 usage_prot_P36035 usage_prot_P36035 prot_pool --> prot_P36035 0.0 usage_prot_P36051 usage_prot_P36051 prot_pool --> prot_P36051 0.0 usage_prot_P36060 usage_prot_P36060 prot_pool --> prot_P36060 0.0 usage_prot_P36062 usage_prot_P36062 prot_pool --> prot_P36062 0.0 -usage_prot_P36076 usage_prot_P36076 prot_pool --> prot_P36076 0.00034431167774727115 +usage_prot_P36076 usage_prot_P36076 prot_pool --> prot_P36076 0.00034431167774345546 usage_prot_P36088 usage_prot_P36088 prot_pool --> prot_P36088 0.0 usage_prot_P36107 usage_prot_P36107 prot_pool --> prot_P36107 0.0 -usage_prot_P36126 usage_prot_P36126 prot_pool --> prot_P36126 0.00013649097499677677 +usage_prot_P36126 usage_prot_P36126 prot_pool --> prot_P36126 0.00013649097499677696 usage_prot_P36136 usage_prot_P36136 prot_pool --> prot_P36136 0.0 usage_prot_P36143 usage_prot_P36143 prot_pool --> prot_P36143 0.0 -usage_prot_P36148 usage_prot_P36148 prot_pool --> prot_P36148 0.07861169805829706 +usage_prot_P36148 usage_prot_P36148 prot_pool --> prot_P36148 0.07861169805829576 usage_prot_P36150 usage_prot_P36150 prot_pool --> prot_P36150 0.0 usage_prot_P36156 usage_prot_P36156 prot_pool --> prot_P36156 0.0 usage_prot_P36165 usage_prot_P36165 prot_pool --> prot_P36165 0.0 usage_prot_P36421 usage_prot_P36421 prot_pool --> prot_P36421 0.09483822346312973 usage_prot_P36973 usage_prot_P36973 prot_pool --> prot_P36973 0.0 -usage_prot_P37012 usage_prot_P37012 prot_pool --> prot_P37012 0.03512278945166966 +usage_prot_P37012 usage_prot_P37012 prot_pool --> prot_P37012 0.03512278945166371 usage_prot_P37020 usage_prot_P37020 prot_pool --> prot_P37020 0.0 usage_prot_P37254 usage_prot_P37254 prot_pool --> prot_P37254 0.02660081780009697 -usage_prot_P37291 usage_prot_P37291 prot_pool --> prot_P37291 0.003034941646448473 +usage_prot_P37291 usage_prot_P37291 prot_pool --> prot_P37291 0.0030349416464495733 usage_prot_P37292 usage_prot_P37292 prot_pool --> prot_P37292 0.0 usage_prot_P37296 usage_prot_P37296 prot_pool --> prot_P37296 0.0 usage_prot_P37297 usage_prot_P37297 prot_pool --> prot_P37297 0.0 usage_prot_P37298 usage_prot_P37298 prot_pool --> prot_P37298 0.0 -usage_prot_P37299 usage_prot_P37299 prot_pool --> prot_P37299 0.1315505255750109 +usage_prot_P37299 usage_prot_P37299 prot_pool --> prot_P37299 0.024366041448197595 usage_prot_P37303 usage_prot_P37303 prot_pool --> prot_P37303 0.0 -usage_prot_P38009 usage_prot_P38009 prot_pool --> prot_P38009 0.22737217693475126 +usage_prot_P38009 usage_prot_P38009 prot_pool --> prot_P38009 0.22737217693473705 usage_prot_P38013 usage_prot_P38013 prot_pool --> prot_P38013 0.0 usage_prot_P38063 usage_prot_P38063 prot_pool --> prot_P38063 0.0 -usage_prot_P38066 usage_prot_P38066 prot_pool --> prot_P38066 7.147813579435674e-06 -usage_prot_P38067 usage_prot_P38067 prot_pool --> prot_P38067 0.0 +usage_prot_P38066 usage_prot_P38066 prot_pool --> prot_P38066 7.1478135795783395e-06 +usage_prot_P38067 usage_prot_P38067 prot_pool --> prot_P38067 0.00035944153463572415 usage_prot_P38071 usage_prot_P38071 prot_pool --> prot_P38071 0.0 usage_prot_P38074 usage_prot_P38074 prot_pool --> prot_P38074 0.0 usage_prot_P38075 usage_prot_P38075 prot_pool --> prot_P38075 0.0 -usage_prot_P38077 usage_prot_P38077 prot_pool --> prot_P38077 2.2018388716452426 +usage_prot_P38077 usage_prot_P38077 prot_pool --> prot_P38077 0.10742544668622254 usage_prot_P38084 usage_prot_P38084 prot_pool --> prot_P38084 0.0 usage_prot_P38085 usage_prot_P38085 prot_pool --> prot_P38085 0.0 usage_prot_P38088 usage_prot_P38088 prot_pool --> prot_P38088 0.0 usage_prot_P38090 usage_prot_P38090 prot_pool --> prot_P38090 0.0 usage_prot_P38113 usage_prot_P38113 prot_pool --> prot_P38113 0.0 usage_prot_P38115 usage_prot_P38115 prot_pool --> prot_P38115 0.0 -usage_prot_P38122 usage_prot_P38122 prot_pool --> prot_P38122 0.0006736985813516832 +usage_prot_P38122 usage_prot_P38122 prot_pool --> prot_P38122 0.0006736985813442173 usage_prot_P38125 usage_prot_P38125 prot_pool --> prot_P38125 0.0 usage_prot_P38127 usage_prot_P38127 prot_pool --> prot_P38127 0.0 usage_prot_P38130 usage_prot_P38130 prot_pool --> prot_P38130 0.0 @@ -7392,17 +7392,17 @@ usage_prot_P38138 usage_prot_P38138 prot_pool --> prot_P38138 0.0 usage_prot_P38139 usage_prot_P38139 prot_pool --> prot_P38139 0.0 usage_prot_P38142 usage_prot_P38142 prot_pool --> prot_P38142 0.0 usage_prot_P38143 usage_prot_P38143 prot_pool --> prot_P38143 0.0 -usage_prot_P38145 usage_prot_P38145 prot_pool --> prot_P38145 0.015806990804100165 +usage_prot_P38145 usage_prot_P38145 prot_pool --> prot_P38145 0.015806990804415662 usage_prot_P38149 usage_prot_P38149 prot_pool --> prot_P38149 0.0 -usage_prot_P38152 usage_prot_P38152 prot_pool --> prot_P38152 0.27926943469257726 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prot_P38230 0.0 @@ -7417,25 +7417,25 @@ usage_prot_P38329 usage_prot_P38329 prot_pool --> prot_P38329 0.0 usage_prot_P38331 usage_prot_P38331 prot_pool --> prot_P38331 0.0 usage_prot_P38342 usage_prot_P38342 prot_pool --> prot_P38342 0.0 usage_prot_P38358 usage_prot_P38358 prot_pool --> prot_P38358 0.0 -usage_prot_P38359 usage_prot_P38359 prot_pool --> prot_P38359 0.09784641520528169 +usage_prot_P38359 usage_prot_P38359 prot_pool --> prot_P38359 0.09784641520528022 usage_prot_P38360 usage_prot_P38360 prot_pool --> prot_P38360 0.0 -usage_prot_P38361 usage_prot_P38361 prot_pool --> prot_P38361 0.1282555221891965 -usage_prot_P38426 usage_prot_P38426 prot_pool --> prot_P38426 0.048017892144392046 -usage_prot_P38427 usage_prot_P38427 prot_pool --> prot_P38427 0.03494722296268555 +usage_prot_P38361 usage_prot_P38361 prot_pool --> prot_P38361 0.12825552218912606 +usage_prot_P38426 usage_prot_P38426 prot_pool --> prot_P38426 0.08177679930245621 +usage_prot_P38427 usage_prot_P38427 prot_pool --> prot_P38427 0.0 usage_prot_P38604 usage_prot_P38604 prot_pool --> prot_P38604 0.26143653126923944 -usage_prot_P38620 usage_prot_P38620 prot_pool --> prot_P38620 0.01155076481859114 -usage_prot_P38625 usage_prot_P38625 prot_pool --> prot_P38625 0.00013646473803005836 +usage_prot_P38620 usage_prot_P38620 prot_pool --> prot_P38620 0.011550764818590518 +usage_prot_P38625 usage_prot_P38625 prot_pool --> prot_P38625 0.0001364647380301152 usage_prot_P38626 usage_prot_P38626 prot_pool --> prot_P38626 0.00025515998385280156 -usage_prot_P38627 usage_prot_P38627 prot_pool --> prot_P38627 0.008027422902512507 +usage_prot_P38627 usage_prot_P38627 prot_pool --> prot_P38627 0.008027422902512509 usage_prot_P38628 usage_prot_P38628 prot_pool --> prot_P38628 0.002919769026712837 usage_prot_P38631 usage_prot_P38631 prot_pool --> prot_P38631 0.0 usage_prot_P38635 usage_prot_P38635 prot_pool --> prot_P38635 0.00012136731032743427 usage_prot_P38689 usage_prot_P38689 prot_pool --> prot_P38689 0.0 usage_prot_P38693 usage_prot_P38693 prot_pool --> prot_P38693 0.0 usage_prot_P38695 usage_prot_P38695 prot_pool --> prot_P38695 0.0 -usage_prot_P38697 usage_prot_P38697 prot_pool --> prot_P38697 0.06808457429244913 -usage_prot_P38698 usage_prot_P38698 prot_pool --> prot_P38698 0.16361767872931243 -usage_prot_P38702 usage_prot_P38702 prot_pool --> prot_P38702 0.011059341306809403 +usage_prot_P38697 usage_prot_P38697 prot_pool --> prot_P38697 0.06808457429248614 +usage_prot_P38698 usage_prot_P38698 prot_pool --> prot_P38698 0.16725781740352613 +usage_prot_P38702 usage_prot_P38702 prot_pool --> prot_P38702 0.010970312710978484 usage_prot_P38703 usage_prot_P38703 prot_pool --> prot_P38703 0.0 usage_prot_P38705 usage_prot_P38705 prot_pool --> prot_P38705 0.003925578898246396 usage_prot_P38707 usage_prot_P38707 prot_pool --> prot_P38707 0.09499696579955424 @@ -7444,23 +7444,23 @@ usage_prot_P38709 usage_prot_P38709 prot_pool --> prot_P38709 0.0714294663242009 usage_prot_P38710 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prot_pool_exchange --> prot_pool 133.11112647681796 -usage_prot_standard usage_prot_standard prot_pool --> prot_standard 0.20702899530096816 +prot_pool_exchange prot_pool_exchange --> prot_pool 86.41847952906397 +usage_prot_standard usage_prot_standard prot_pool --> prot_standard 0.2091964660420879 diff --git a/src/overflow/build.py b/src/overflow/build.py index 76d5cee..9e3e35a 100644 --- a/src/overflow/build.py +++ b/src/overflow/build.py @@ -24,6 +24,7 @@ from overflow.biomass import apply_protein_content from overflow.config import ( BIO_RXN, + BYPRODUCT_RXNS, C_SOURCE, CO2_RXN, CONDITION_ORDER, @@ -49,12 +50,13 @@ MinimumUsageResult, RateFitResult, apply_concentrations, - flexibilize_proteins, minimum_usage_pass, + relax_to_growth, relax_to_measured_rates, write_back_concentrations, ) from overflow.ngam import NgamFit, fit_ngam, parsimonious_solution +from overflow.respiratory_kcats import apply_respiratory_kcats from overflow.proteomics import ( condition_prot_data, molecular_masses, @@ -104,6 +106,7 @@ def build_condition( uptake_flex: float = 1.05, objective: str = "protein", block: Sequence[str] = (), + respiratory_kcats: Optional[pd.DataFrame] = None, verbose: bool = True, ) -> BuildResult: """Build one proteome-constrained ecModel. @@ -127,6 +130,9 @@ def build_condition( reactions only (``"metabolic-flux"``); both need ``fit_rates``. ``block`` lists reactions to close before anything else is applied. + + ``respiratory_kcats`` replaces the kcats of the respiratory complexes + with those derived by :mod:`overflow.respiratory_kcats`. """ if objective not in OBJECTIVES: raise ValueError(f"objective must be one of {OBJECTIVES}, not {objective!r}") @@ -145,6 +151,8 @@ def build_condition( ) model = load_model(build_adapter(condition)) + if respiratory_kcats is not None: + apply_respiratory_kcats(model, respiratory_kcats) free_ngam(model) block_reactions(model, block) @@ -176,7 +184,7 @@ def build_condition( result.minimum_usage = minimum_usage_pass(model, condition.d_rate) apply_concentrations(model, result.minimum_usage.concentrations) - result.flexibilization = flexibilize_proteins(model, condition.d_rate) + result.flexibilization = relax_to_growth(model, condition.d_rate) if fit_rates and result.flexibilization.reached_target: constrain_measured_rates(model, condition, tolerance=rate_tolerance) result.rate_fit = relax_to_measured_rates(model, condition.d_rate) @@ -189,12 +197,11 @@ def build_condition( if not result.flexibilization.reached_target: raise InfeasibleCondition( f"{condition.name}: the model reaches " - f"{result.flexibilization.growth:.5f} /h after releasing " - f"{len(result.flexibilization.released)} enzyme caps and growing the " - f"protein pool {result.flexibilization.pool_increases} times, short of " + f"{result.flexibilization.growth:.5f} /h with every measured cap and the " + f"protein pool free to grow, short of " f"the dilution rate {condition.d_rate}. Protein is not what limits it: " "check the carbon budget, the biomass composition and the maintenance " - "cost before flexibilizing further." + "cost." ) if fit_rates: @@ -269,8 +276,8 @@ def report(result: BuildResult) -> None: f"pool={result.pool_size:.1f} mg/gDW\n" f" {result.n_kept} proteins kept, {result.n_measured} are model enzymes, " f"{len(result.minimum_usage.raised)} raised to their minimum usage\n" - f" flexibilized {len(flex.released)} enzymes, pool grown " - f"{flex.pool_increases}x ({flex.pool_before:.1f}->{flex.pool_after:.1f})\n" + f" relaxed {len(flex.released)} abundances to reach the dilution rate, pool " + f"{flex.pool_before:.1f}->{flex.pool_after:.1f}\n" + (f" relaxed {len(result.rate_fit.proteins)} abundances to fit the " f"measured rates, adding {result.rate_fit.added_mg:.2f} mg/gDW\n" if result.rate_fit else "") @@ -339,12 +346,33 @@ def summary_table(results: list[BuildResult]) -> pd.DataFrame: "glucose": round(result.glucose, 4), "CO2": round(float(result.fluxes[CO2_RXN]), 4), "O2": round(-float(result.fluxes[O2_RXN]), 4), + "ethanol": round(float(result.fluxes[BYPRODUCT_RXNS["Ethanol"]]), 4), "pool_used_mg_gDW": round(float(result.fluxes[POOL_RXN]), 1), } ) return pd.DataFrame(rows) +def update_summary(path: Path, summary: pd.DataFrame) -> pd.DataFrame: + """Write the rows of the conditions just built into the summary at ``path``. + + Rows of conditions built by another call are kept, so building the + conditions one at a time gives the same table as building them together. + """ + if path.exists(): + previous = pd.read_csv(path, sep="\t") + kept = previous[~previous["condition"].isin(summary["condition"])] + summary = pd.concat([kept, summary], ignore_index=True) + rank = {name: i for i, name in enumerate(CONDITION_ORDER)} + summary = summary.sort_values( + "condition", key=lambda names: names.map(lambda name: rank.get(name, len(rank))), + kind="stable", + ).reset_index(drop=True) + path.parent.mkdir(parents=True, exist_ok=True) + summary.to_csv(path, sep="\t", index=False) + return summary + + def main(argv: Optional[list[str]] = None) -> int: parser = argparse.ArgumentParser(description=__doc__) parser.add_argument("conditions", nargs="*", default=list(CONDITION_ORDER)) @@ -368,6 +396,11 @@ def main(argv: Optional[list[str]] = None) -> int: help="reaction IDs to close before the model is built, e.g. r_2129 (the " "proton leak)", ) + parser.add_argument( + "--respiratory-kcats", type=Path, metavar="TSV", + help="kcats of the respiratory complexes written by overflow.respiratory_kcats " + "(modelGeneration/respiratoryKcats.tsv), applied before the model is built", + ) parser.add_argument( "--objective", choices=OBJECTIVES, @@ -399,6 +432,9 @@ def main(argv: Optional[list[str]] = None) -> int: conditions = load_conditions() table = read_proteomics() masses = molecular_masses() + respiratory_kcats = ( + pd.read_csv(args.respiratory_kcats, sep="\t") if args.respiratory_kcats else None + ) results = [] for name in args.conditions or CONDITION_ORDER: @@ -414,14 +450,14 @@ def main(argv: Optional[list[str]] = None) -> int: rate_tolerance=args.rate_tolerance, uptake_flex=args.uptake_flex, objective=args.objective, block=args.block, + respiratory_kcats=respiratory_kcats, ) write_outputs(result, args.models_dir, args.results_dir) results.append(result) - summary = summary_table(results) - args.results_dir.mkdir(parents=True, exist_ok=True) - summary.to_csv(args.results_dir / "modelGeneration" / "summary.tsv", - sep="\t", index=False) + summary = update_summary( + args.results_dir / "modelGeneration" / "summary.tsv", summary_table(results) + ) print() print(summary.to_string(index=False)) return 0 diff --git a/src/overflow/complexes.py b/src/overflow/complexes.py index 344fd94..4aa575b 100644 --- a/src/overflow/complexes.py +++ b/src/overflow/complexes.py @@ -1,24 +1,40 @@ -"""Making measured subunit abundances consistent with complex stoichiometry. - -Proteomics recovers the subunits of a membrane-bound complex unevenly, -which leaves a complex whose subunits disagree about how much of it -there is. For the respiratory chain the original analysis replaces the -measurements of a complex's subunits with one abundance per complex, -scaled by each subunit's stoichiometry. - -Abundances here are molar (mmol/gDW), because the stoichiometry they are -divided by is molar. +"""Enzyme complexes: grouping the subunits, and one abundance per complex. + +Proteomics recovers the subunits of a complex unevenly: subunits present +1:1 can be measured several-fold apart while their replicates agree. Capped +one by one, a complex could then carry no more flux than its least abundant +measurement allows. Every complex is therefore given one abundance, the +median over its measured subunits of abundance / copies, scaled back to each +subunit by its copies, and the build raises a complex's subunits together. + +A complex is a set of enzymes that catalyses a reaction together +(``ec.rxn_enz_mat``). Two enzyme sets are one complex when they share at +least two subunits and at least half of the larger set (isozyme variants +that swap a subunit, the same complex on different reactions). A single +shared protein never merges two sets, so electron carriers and shared +subunits (cytochrome c, thioredoxin, the E3 subunit of the 2-oxo-acid +dehydrogenases) do not chain unrelated complexes together. A subunit in +exactly two complexes belongs to the one whose enzyme sets catalyse more +reactions (COX1-3 of complex IV also appear in an assembly reaction). A +subunit in three or more complexes, in two with equal weight, or that also +catalyses a reaction on its own is *shared*: it keeps its own measurement. + +Abundances here are molar (mmol/gDW), because the copies they are divided +by are molar. """ from __future__ import annotations +import logging from dataclasses import dataclass, field -from typing import TYPE_CHECKING, Iterable, Sequence +from typing import TYPE_CHECKING, Optional, Sequence import numpy as np if TYPE_CHECKING: # pragma: no cover - typing only from geckopy import EcModel +logger = logging.getLogger(__name__) + @dataclass class ComplexFixResult: @@ -26,6 +42,31 @@ class ComplexFixResult: abundances: np.ndarray added: list[str] = field(default_factory=list) adjusted: list[str] = field(default_factory=list) + shared: list[str] = field(default_factory=list) + + +@dataclass +class ComplexFamilies: + """The complexes of an ecModel. + + ``complexes`` holds one ``{enzyme: copies}`` per complex over every + subunit in any of its enzyme sets; ``owner`` maps each subunit that + belongs to a complex to its index; ``shared`` are the subunits that + belong to none. + """ + + complexes: list[dict[str, float]] = field(default_factory=list) + owner: dict[str, int] = field(default_factory=dict) + shared: set[str] = field(default_factory=set) + + def owned(self, index: int) -> dict[str, float]: + """``{enzyme: copies}`` of the subunits complex ``index`` owns.""" + return {e: c for e, c in self.complexes[index].items() if self.owner.get(e) == index} + + def members(self, enzyme: str) -> list[str]: + """The subunits of the complex ``enzyme`` belongs to, or ``[enzyme]``.""" + index = self.owner.get(enzyme) + return [enzyme] if index is None else list(self.owned(index)) def complex_subunits(model: "EcModel", base_reaction: str) -> list[tuple[str, np.ndarray]]: @@ -50,46 +91,106 @@ def complex_subunits(model: "EcModel", base_reaction: str) -> list[tuple[str, np return variants -def fix_complexes( +def complex_families(model: "EcModel", min_overlap: float = 0.5, min_shared: int = 2) -> ComplexFamilies: + """Group the enzymes of multi-subunit reactions into complexes (see the module text).""" + matrix = model.ec.rxn_enz_mat.tocsr() + enzymes = list(model.ec.enzymes) + sets: dict[frozenset, dict[str, float]] = {} + reactions: dict[frozenset, int] = {} + alone: set[str] = set() + for row in range(matrix.shape[0]): + start, end = matrix.indptr[row], matrix.indptr[row + 1] + present = {enzymes[j]: float(v) for j, v in zip(matrix.indices[start:end], matrix.data[start:end]) if v} + if len(present) == 1: + alone.update(present) + elif present: + key = frozenset(present) + sets.setdefault(key, present) + reactions[key] = reactions.get(key, 0) + 1 + + keys = list(sets) + parent = list(range(len(keys))) + + def find(i: int) -> int: + while parent[i] != i: + parent[i] = parent[parent[i]] + i = parent[i] + return i + + by_enzyme: dict[str, list[int]] = {} + for i, key in enumerate(keys): + for enzyme in key: + by_enzyme.setdefault(enzyme, []).append(i) + for indices in by_enzyme.values(): + for x in range(len(indices)): + for y in range(x + 1, len(indices)): + i, j = indices[x], indices[y] + common = len(keys[i] & keys[j]) + if common >= min_shared and common >= min_overlap * max(len(keys[i]), len(keys[j])): + parent[find(i)] = find(j) + + grouped: dict[int, dict[str, float]] = {} + weight: dict[int, dict[str, int]] = {} + for i, key in enumerate(keys): + w = weight.setdefault(find(i), {}) + complex_ = grouped.setdefault(find(i), {}) + for enzyme, copies in sets[key].items(): + w[enzyme] = w.get(enzyme, 0) + reactions[key] + if enzyme in complex_ and complex_[enzyme] != copies: + logger.warning("%s has %g copies in one variant and %g in another; the first is used", + enzyme, complex_[enzyme], copies) + complex_.setdefault(enzyme, copies) + roots = list(grouped) + complexes = [grouped[r] for r in roots] + + found: dict[str, list[tuple[int, int]]] = {} + for index, root in enumerate(roots): + for enzyme, w in weight[root].items(): + found.setdefault(enzyme, []).append((w, index)) + owner: dict[str, int] = {} + for enzyme, hits in found.items(): + if enzyme in alone or len(hits) > 2: + continue + hits.sort(reverse=True) + if len(hits) == 1 or hits[0][0] > hits[1][0]: + owner[enzyme] = hits[0][1] + return ComplexFamilies(complexes=complexes, owner=owner, shared=set(found) - set(owner)) + + +def level_complexes( model: "EcModel", - base_reactions: Iterable[str], uniprot_ids: Sequence[str], abundances: np.ndarray, + families: Optional[ComplexFamilies] = None, ) -> ComplexFixResult: - """Rewrite subunit abundances to one abundance per complex. - - Each subunit is set to ``stoichiometry * mean(measured / stoichiometry)`` - over the subunits that were measured. A subunit of the complex that - was not measured is added to the data at its stoichiometric share, so - a complex is never limited by a subunit that simply was not seen. + """Give every complex one abundance: the median per copy over its measured subunits. - A complex with no measured subunit at all is left alone. + Unmeasured subunits a complex owns are added at their share, so a + complex is never limited by a subunit that simply was not seen. A + subunit measured at zero counts as unseen. Shared subunits keep their + measurement. """ - values = {protein: float(value) for protein, value in zip(uniprot_ids, abundances)} + families = families or complex_families(model) + values = {p: float(a) for p, a in zip(uniprot_ids, abundances)} order = list(uniprot_ids) - result = ComplexFixResult(uniprot_ids=order, abundances=np.asarray(abundances, float)) - - for base in base_reactions: - for _, subunits in complex_subunits(model, base): - measured = [ - (protein, values[protein] / stoichiometry) - for protein, stoichiometry in subunits - if protein in values and values[protein] > 0 - ] - if not measured: - continue - per_complex = float(np.mean([v for _, v in measured])) - for protein, stoichiometry in subunits: - new_value = stoichiometry * per_complex - if protein in values: - if values[protein] != new_value: - result.adjusted.append(protein) - values[protein] = new_value - else: - order.append(protein) - values[protein] = new_value - result.added.append(protein) - + result = ComplexFixResult(uniprot_ids=order, abundances=np.asarray(abundances, float), + shared=sorted(families.shared & set(values))) + for index in range(len(families.complexes)): + members = families.owned(index) + measured = [values[e] / c for e, c in members.items() if values.get(e, 0) > 0] + if not measured: + continue + per_copy = float(np.median(measured)) + for enzyme, copies in members.items(): + level = per_copy * copies + if values.get(enzyme, 0) > 0: + if not np.isclose(values[enzyme], level): + result.adjusted.append(enzyme) + else: + if enzyme not in values: + order.append(enzyme) + result.added.append(enzyme) + values[enzyme] = level result.uniprot_ids = order result.abundances = np.array([values[p] for p in order], dtype=float) return result diff --git a/src/overflow/config.py b/src/overflow/config.py index abea371..5ef3720 100644 --- a/src/overflow/config.py +++ b/src/overflow/config.py @@ -47,10 +47,6 @@ "Formate": "r_1793", } -#: Oxidative phosphorylation reactions whose complexes the original -#: analysis treated as a unit. -OXPHOS_RXNS = ("r_1021", "r_0439", "r_0438", "r_0226") - #: Prefix of the replicate columns in ``abs_proteomics.txt`` per condition. #: hGR is the odd one out -- its columns are named ``CN_hGR_*``. REPLICATE_PREFIX = { diff --git a/src/overflow/flexibilize.py b/src/overflow/flexibilize.py index ac7ba87..9e9e219 100644 --- a/src/overflow/flexibilize.py +++ b/src/overflow/flexibilize.py @@ -1,18 +1,23 @@ """Reconciling measured enzyme abundances with what the model needs. -Two passes, in the order the original analysis applies them: +Three steps, each treating an enzyme complex as one unit +(:func:`overflow.complexes.complex_families`): when a complex needs more +capacity all its measured subunits are raised by the same factor, so a +complex levelled to one abundance stays levelled. 1. A minimum-usage pass on a model constrained only by the protein pool. - An enzyme the model cannot run at the measured dilution rate for less - than its measured abundance has that abundance raised to what the - model needs. This catches enzymes whose kcat is too low for the - measurement, before any of them are allowed to limit growth. -2. Iterative flexibilization of whatever still limits growth. The most - limiting enzyme is released outright, one at a time, until the model - reaches the dilution rate; if nothing single is limiting, the protein - pool itself is grown. The released enzymes are then re-tightened to - the usage they take in a minimum-protein solution, so releasing an - enzyme costs only what the model actually spends on it. + A complex the model cannot run at the dilution rate for less than its + measured abundance is raised to what the model needs. This catches + enzymes whose kcat is too low for the measurement, before any of them + are allowed to limit growth. +2. The least relaxation that reaches the dilution rate + (:func:`relax_to_growth`): one LP minimises the sum of the fold + increases of the measured caps, and of the protein pool at a far + higher price, so the answer does not depend on the order in which + limiting caps are found. +3. With measured rates, the least further relaxation that reproduces them + (:func:`relax_to_measured_rates`), the same LP under the rate + constraints. """ from __future__ import annotations @@ -21,8 +26,9 @@ import numpy as np import pandas as pd -from geckopy import constrain_enz_concs, get_conc_control_coeffs +from geckopy import constrain_enz_concs +from overflow.complexes import complex_families from overflow.config import BIO_RXN, POOL_RXN if TYPE_CHECKING: # pragma: no cover - typing only @@ -57,7 +63,7 @@ def table(self) -> pd.DataFrame: @dataclass class FlexibilizationResult: - """Outcome of the iterative flexibilization.""" + """Outcome of the relaxation to the dilution rate.""" released: list[str] = field(default_factory=list) previous: list[float] = field(default_factory=list) @@ -109,191 +115,42 @@ def minimum_usage_pass( biomass = model.reactions.get_by_id(bio_rxn) original_bounds = biomass.bounds biomass.lower_bound = target_growth + usages: dict[int, float] = {} try: for index in measured_enzymes(model): - enzyme = model.ec.enzymes[index] - reaction_id = f"{USAGE_PREFIX}{enzyme}" + reaction_id = f"{USAGE_PREFIX}{model.ec.enzymes[index]}" with model: model.objective = reaction_id model.objective.direction = "min" solution = model.optimize() - usage = ( - float(solution.fluxes[reaction_id]) - if solution.status == "optimal" - else None - ) - if usage is not None and usage > concentrations[index]: - result.raised.append(enzyme) - result.previous.append(float(concentrations[index])) - result.minimum.append(tolerance * usage) - concentrations[index] = tolerance * usage + if solution.status == "optimal": + usages[index] = float(solution.fluxes[reaction_id]) finally: biomass.bounds = original_bounds - result.concentrations = concentrations - return result - - -def flexibilize_proteins( - model: "EcModel", - target_growth: float, - max_iterations: int = 500, - pool_step: float = 1.01, - growth_tolerance: float = 1e-4, - bound_tolerance: float = 1e-6, - fold_change: float = 100.0, - patience: int = 25, - bio_rxn: str = BIO_RXN, - pool_rxn: str = POOL_RXN, -) -> FlexibilizationResult: - """Release limiting enzymes until the model reaches ``target_growth``. - - The model is expected to carry its condition constraints and its - enzyme caps. Growth is maximised throughout; the caller decides what - the objective should be afterwards. - """ - pool = model.reactions.get_by_id(pool_rxn) - result = FlexibilizationResult(pool_before=pool.upper_bound) - - biomass = model.reactions.get_by_id(bio_rxn) - biomass.lower_bound = 0.0 - model.objective = bio_rxn - model.objective.direction = "max" - - original: dict[str, float] = {} - threshold = target_growth * (1 - growth_tolerance) - - best_growth = -np.inf - stalled = 0 - for _ in range(max_iterations): - solution = model.optimize() - growth = solution.objective_value if solution.status == "optimal" else 0.0 - growth = float(growth or 0.0) - if growth >= threshold: - break - - if growth > best_growth + growth_tolerance * target_growth: - best_growth, stalled = growth, 0 - else: - stalled += 1 - if stalled > patience: - break - - enzyme = _most_limiting(model, solution, bound_tolerance, fold_change) - if enzyme is not None: - reaction = model.reactions.get_by_id(f"{USAGE_PREFIX}{enzyme}") - original.setdefault(enzyme, reaction.upper_bound) - reaction.upper_bound = FREE - result.released.append(enzyme) - else: - pool.upper_bound *= pool_step - result.pool_increases += 1 - - solution = model.optimize() - result.growth = float(solution.objective_value or 0.0) - result.reached_target = result.growth >= threshold - result.pool_after = pool.upper_bound - - _retighten(model, target_growth, original, result, bio_rxn, pool_rxn) - return result - - -def binding_caps(model: "EcModel", solution, bound_tolerance: float) -> list[str]: - """Enzymes sitting at a cap that is not already released. - - Only an enzyme at its own cap can be limiting through that cap. An - enzyme that merely carries flux also has a positive shadow price - whenever the protein pool binds -- the price of the pool, not of the - cap -- so considering those would keep re-releasing enzymes that are - already free while the real constraint went untouched. - """ - candidates = [] - for enzyme in model.ec.enzymes: - reaction = model.reactions.get_by_id(f"{USAGE_PREFIX}{enzyme}") - if reaction.upper_bound >= FREE: + families = complex_families(model) + position = {e: i for i, e in enumerate(model.ec.enzymes)} + done: set[int] = set() + for index in measured_enzymes(model): + if index in done: continue - usage = float(solution.fluxes[reaction.id]) - if usage >= (1 - bound_tolerance) * reaction.upper_bound: - candidates.append(enzyme) - return candidates - - -def _most_limiting( - model: "EcModel", - solution, - bound_tolerance: float, - fold_change: float = 100.0, -) -> Optional[str]: - """The capped enzyme worth the most growth, if any. - - Shadow prices answer this in one solve, but they go silent on a - degenerate optimum: when several caps bind at once only one of them - carries a non-zero dual, and sometimes none does. Falling back to - probing each candidate cap directly costs one solve per candidate - but cannot be fooled that way, which is what keeps a degenerate - model from looking as though nothing at all were limiting it. - """ - candidates = binding_caps(model, solution, bound_tolerance) - if not candidates: - return None - - _, coefficients = get_conc_control_coeffs(model, proteins=candidates) - if coefficients.size and coefficients.max() > 0: - return candidates[int(np.argmax(coefficients))] - - baseline = float(solution.objective_value or 0.0) - best, best_gain = None, 0.0 - for enzyme in candidates: - reaction = model.reactions.get_by_id(f"{USAGE_PREFIX}{enzyme}") - previous = reaction.upper_bound - reaction.upper_bound = min(previous * fold_change, FREE) if previous else FREE - try: - probe = model.optimize() - finally: - reaction.upper_bound = previous - if probe.status != "optimal": + group = [position[m] for m in families.members(model.ec.enzymes[index]) + if m in position and not np.isnan(concentrations[position[m]])] + done.update(group) + if not any(usages.get(i, 0.0) > concentrations[i] for i in group): continue - gain = float(probe.objective_value or 0.0) - baseline - if gain > best_gain: - best, best_gain = enzyme, gain - return best + fold = max((tolerance * usages[i] / concentrations[i] + for i in group if i in usages and concentrations[i] > 0), default=1.0) + for i in group: + raised = concentrations[i] * fold if concentrations[i] > 0 else tolerance * usages.get(i, 0.0) + if raised > concentrations[i]: + result.raised.append(model.ec.enzymes[i]) + result.previous.append(float(concentrations[i])) + result.minimum.append(float(raised)) + concentrations[i] = raised - -def _retighten( - model: "EcModel", - target_growth: float, - original: dict[str, float], - result: FlexibilizationResult, - bio_rxn: str = BIO_RXN, - pool_rxn: str = POOL_RXN, -) -> None: - """Pull the released enzymes back to a minimum-protein solution. - - Released enzymes keep their previous cap where the minimum-protein - solution does not use them at all, so a release that turned out to be - unnecessary leaves no trace. - """ - biomass = model.reactions.get_by_id(bio_rxn) - biomass.lower_bound = 0.9999 * target_growth - model.objective = pool_rxn - model.objective.direction = "min" - solution = model.optimize() - - result.previous = [original[e] for e in result.released] - if solution.status != "optimal": - result.modified = list(result.previous) - for enzyme, previous in zip(result.released, result.previous): - model.reactions.get_by_id(f"{USAGE_PREFIX}{enzyme}").upper_bound = previous - return - - modified: list[float] = [] - for enzyme, previous in zip(result.released, result.previous): - reaction = model.reactions.get_by_id(f"{USAGE_PREFIX}{enzyme}") - usage = float(solution.fluxes[reaction.id]) - new_bound = usage if usage > 0 else previous - reaction.upper_bound = new_bound - modified.append(new_bound) - result.modified = modified + result.concentrations = concentrations + return result def write_back_concentrations(model: "EcModel") -> None: @@ -350,11 +207,63 @@ def relax_to_measured_rates( ) -> RateFitResult: """Raise measured abundances by the least that fits the measured rates. - The model is expected to carry its rate constraints already. Each - measured enzyme's cap becomes ``usage <= measured + slack``, and the - slacks are minimised, so the answer is the smallest departure from - the proteomics that accounts for the rates rather than one enzyme's - cap released outright. + See :func:`_minimal_relaxation`; the model carries its rate constraints. + """ + return _minimal_relaxation(model, target_growth, weight, bio_rxn, floor)[0] + + +def relax_to_growth( + model: "EcModel", + target_growth: float, + weight: str = "relative", + pool_weight: float = 1000.0, + bio_rxn: str = BIO_RXN, + pool_rxn: str = POOL_RXN, + floor: float = 1e-9, +) -> FlexibilizationResult: + """Raise measured abundances, and if need be the pool, by the least that reaches ``target_growth``. + + One LP chooses every relaxation at once (see :func:`_minimal_relaxation`), + so the result does not depend on the order in which limiting caps + would be found. The protein pool can grow by a fold too, at + ``pool_weight`` times the price of an enzyme's fold, so that it grows + only where no relaxation of enzymes suffices. + """ + pool = model.reactions.get_by_id(pool_rxn) + result = FlexibilizationResult(pool_before=pool.upper_bound) + fit, pool_fold = _minimal_relaxation( + model, target_growth, weight, bio_rxn, floor, pool_weight=pool_weight, pool_rxn=pool_rxn, + ) + result.released, result.previous, result.modified = fit.proteins, fit.measured, fit.relaxed + result.pool_increases = int(pool_fold > 1e-9) + result.pool_after = pool.upper_bound + model.objective = bio_rxn + model.objective.direction = "max" + solution = model.optimize() + result.growth = float(solution.objective_value or 0.0) if solution.status == "optimal" else 0.0 + result.reached_target = fit.feasible and result.growth >= target_growth * (1 - 1e-4) + return result + + +def _minimal_relaxation( + model: "EcModel", + target_growth: float, + weight: str = "relative", + bio_rxn: str = BIO_RXN, + floor: float = 1e-9, + pool_weight: Optional[float] = None, + pool_rxn: str = POOL_RXN, +) -> tuple[RateFitResult, float]: + """The least relaxation of measured abundances that reaches ``target_growth``. + + Whatever else constrains the model (the measured rates, for the rate + fit) stays in place. Each measured enzyme's cap becomes + ``usage <= measured * (1 + x)``, with one ``x`` per complex (shared by + its measured subunits; a subunit measured at zero is its own unit) or + per enzyme, and the ``x`` are minimised, so the answer is the smallest + departure from the proteomics rather than one enzyme's cap released + outright. With ``pool_weight`` the protein pool may grow by a fold too, + at that price per fold. Returns the result and the pool's fold. ``weight`` decides what "smallest" means: ``"relative"`` minimises the sum of fold-increases, so an enzyme measured at almost nothing @@ -367,7 +276,7 @@ def relax_to_measured_rates( raise ValueError(f"unknown weight {weight!r}") biomass = model.reactions.get_by_id(bio_rxn) - biomass.bounds = (target_growth, biomass.upper_bound or 1000.0) + biomass.bounds = (target_growth, max(biomass.upper_bound or 1000.0, target_growth)) # The slack objective is this function's own business; the caller's # objective has to survive it, or the model comes back optimising @@ -376,49 +285,84 @@ def relax_to_measured_rates( previous_direction = model.objective.direction indices = measured_enzymes(model) - slacks, added = {}, [] + families = complex_families(model) + position = {e: i for i, e in enumerate(model.ec.enzymes)} + measured = set(indices) + groups, done = [], set() for index in indices: - enzyme = model.ec.enzymes[index] - reaction = model.reactions.get_by_id(f"{USAGE_PREFIX}{enzyme}") - concentration = float(model.ec.concs[index]) - reaction.upper_bound = FREE - slack = model.problem.Variable(f"relax_{enzyme}", lb=0.0, ub=FREE) - constraint = model.problem.Constraint( - reaction.flux_expression - slack, ub=concentration, name=f"cap_{enzyme}" - ) - slacks[enzyme] = (slack, concentration) - added.extend([slack, constraint]) + if index in done: + continue + # a subunit measured at zero cannot share a fold with the others + if not model.ec.concs[index] > 0: + group = [index] + else: + group = [position[m] for m in families.members(model.ec.enzymes[index]) + if m in position and position[m] in measured and position[m] not in done + and model.ec.concs[position[m]] > 0] + done.update(group) + groups.append(group) + + folds, added = [], [] + pool_x = 0.0 + for k, group in enumerate(groups): + fold = model.problem.Variable(f"relax_{k}", lb=0.0, ub=None) + added.append(fold) + for index in group: + enzyme = model.ec.enzymes[index] + reaction = model.reactions.get_by_id(f"{USAGE_PREFIX}{enzyme}") + concentration = float(model.ec.concs[index]) + reaction.upper_bound = FREE + added.append(model.problem.Constraint( + reaction.flux_expression - max(concentration, floor) * fold, + ub=concentration, name=f"cap_{enzyme}", + )) + folds.append((fold, group)) + pool_fold = None + if pool_weight is not None: + pool = model.reactions.get_by_id(pool_rxn) + pool_cap = pool.upper_bound + pool_fold = model.problem.Variable("relax_pool", lb=0.0, ub=None) + pool.upper_bound = FREE + added += [pool_fold, model.problem.Constraint( + pool.flux_expression - pool_cap * pool_fold, ub=pool_cap, name="cap_pool")] model.add_cons_vars(added) try: - model.objective = model.problem.Objective( - add([ - (1.0 / max(concentration, floor) if weight == "relative" else 1.0) * slack - for slack, concentration in slacks.values() - ]), - direction="min", - ) + terms = [ + (1.0 if weight == "relative" else sum(max(float(model.ec.concs[i]), floor) for i in group)) * fold + for fold, group in folds + ] + if pool_fold is not None: + terms.append(pool_weight * (1.0 if weight == "relative" else pool_cap) * pool_fold) + model.objective = model.problem.Objective(add(terms), direction="min") solution = model.optimize() result = RateFitResult(status=solution.status) result.feasible = solution.status == "optimal" if result.feasible: values = model.solver.primal_values concentrations = np.asarray(model.ec.concs, dtype=float).copy() - for enzyme, (slack, concentration) in slacks.items(): - raised = concentration + float(values.get(slack.name, 0.0)) - if raised > concentration * (1 + 1e-9) + 1e-12: - result.proteins.append(enzyme) - result.measured.append(concentration) - result.relaxed.append(raised) - result.added_mg += raised - concentration - concentrations[model.ec.enzymes.index(enzyme)] = raised + for fold, group in folds: + x = float(values.get(fold.name, 0.0)) + for index in group: + concentration = float(model.ec.concs[index]) + raised = concentration + max(concentration, floor) * x + if raised > concentration * (1 + 1e-9) + 1e-12: + result.proteins.append(model.ec.enzymes[index]) + result.measured.append(concentration) + result.relaxed.append(raised) + result.added_mg += raised - concentration + concentrations[index] = raised model.ec.concs = concentrations + if pool_fold is not None: + pool_x = float(values.get(pool_fold.name, 0.0)) finally: model.remove_cons_vars(added) + if pool_fold is not None: + model.reactions.get_by_id(pool_rxn).upper_bound = pool_cap * (1 + pool_x) if result.feasible else pool_cap model.objective = model.problem.Objective( previous_objective, direction=previous_direction ) if result.feasible: constrain_enz_concs(model) - return result + return result, (pool_x if pool_fold is not None and result.feasible else 0.0) diff --git a/src/overflow/proteomics.py b/src/overflow/proteomics.py index 94ff8d6..64e8b5f 100644 --- a/src/overflow/proteomics.py +++ b/src/overflow/proteomics.py @@ -253,12 +253,12 @@ def condition_prot_data( The f-factor and the protein-content rescaling come from the unfiltered replicate means, as they describe the proteome as a whole. The abundances that constrain enzymes come from the filtered - set, optionally after levelling the respiratory complexes. + set, optionally after levelling every enzyme complex to one abundance + (:func:`overflow.complexes.level_complexes`). """ from geckopy.databases import ProtData - from overflow.complexes import fix_complexes - from overflow.config import OXPHOS_RXNS + from overflow.complexes import level_complexes if table is None: table = read_proteomics() @@ -275,7 +275,7 @@ def condition_prot_data( kept_ids, kept_values = list(filtered.uniprot_ids), filtered.abundances complex_fix = None if fix_complex_subunits: - complex_fix = fix_complexes(model, OXPHOS_RXNS, kept_ids, kept_values) + complex_fix = level_complexes(model, kept_ids, kept_values) kept_ids, kept_values = complex_fix.uniprot_ids, complex_fix.abundances return ConditionProteomics( diff --git a/src/overflow/respiratory_kcats.py b/src/overflow/respiratory_kcats.py new file mode 100644 index 0000000..d5e4da4 --- /dev/null +++ b/src/overflow/respiratory_kcats.py @@ -0,0 +1,131 @@ +"""Respiratory-chain kcats derived from the data. + +With the ecModel's kcats the measured respiratory chain cannot carry the +measured respiration in several conditions, so the build raises its +abundances to whatever the fluxes need and its capacity usage reads 100% +by construction. Instead, the kcats of complex III, complex IV and ATP +synthase are derived from the conditions themselves. + +In each condition the apparent turnover of a complex is its sampled flux +(``randomSampling/allFluxes.tsv``, the conventional model constrained by +the measured rates, which uses no kcats) over the complex abundance the +build uses: the filtered mean + 1.96 SD of its measured subunits, +levelled to one abundance per complex (the median per copy). The highest apparent turnover +across the conditions becomes the complex's kcat, for every isozyme +variant of the forward reaction. The condition that sets it runs the +complex at full capacity, and the derived kcat is a lower bound. + +Writes ``modelGeneration/respiratoryTurnover.tsv`` (every condition) and +``modelGeneration/respiratoryKcats.tsv`` (what ``overflow.build +--respiratory-kcats`` applies). +""" +from __future__ import annotations + +import argparse +from pathlib import Path +from typing import Mapping, Optional + +import numpy as np +import pandas as pd + +from overflow.solver import HELP, use_solver +from overflow.adapter import load_model +from overflow.complexes import complex_families, complex_subunits +from overflow.config import CONDITION_ORDER, RESULTS_DIR, load_conditions +from overflow.proteomics import condition_prot_data, molecular_masses, read_proteomics + +#: The complexes whose kcats are derived, by base reaction. +COMPLEXES = {"complex III": "r_0439", "complex IV": "r_0438", "ATP synthase": "r_0226"} + + +def variants(model, base: str) -> list[str]: + """The forward isozyme variants of a reaction in ``model.ec.rxns``.""" + return [r for r in model.ec.rxns if r == base or r.startswith(base + "_EXP_")] + + +def complex_abundance(model, base: str, molar: Mapping[str, float], families) -> float: + """Abundance of a complex [mmol/gDW] over the subunits it owns, per copy. + + The levelled subunits all carry the same abundance per copy; subunits + shared with other complexes (cytochrome c in complexes III and IV) + keep their own and are left out. + """ + _, subunits = complex_subunits(model, base)[0] + owners = {families.owner[p] for p, _ in subunits if p in families.owner} + if len(owners) != 1: + raise ValueError(f"{base}: its subunits belong to {len(owners)} complexes") + owned = families.owned(owners.pop()) + values = [molar[p] / copies for p, copies in owned.items() if molar.get(p, 0) > 0] + return float(np.mean(values)) if values else float("nan") + + +def apparent_turnovers(model, conditions, sampled: pd.DataFrame, table=None, masses=None) -> pd.DataFrame: + """Apparent turnover [1/s] of each complex in each condition.""" + if table is None: + table = read_proteomics() + if masses is None: + masses = molecular_masses() + kcat = dict(zip(model.ec.rxns, np.asarray(model.ec.kcat, dtype=float))) + families = complex_families(model) + rows = [] + for name, condition in conditions.items(): + levelled = condition_prot_data(condition, model, table=table, masses=masses).complex_fix + molar = dict(zip(levelled.uniprot_ids, levelled.abundances)) + for complex_name, base in COMPLEXES.items(): + flux = abs(float(sampled.loc[base, f"{name}_AVERAGE"])) + abundance = complex_abundance(model, base, molar, families) + rows.append(dict( + condition=name, complex=complex_name, reaction=base, + flux_mmol_gDW_h=flux, abundance_nmol_gDW=abundance * 1e6, + apparent_turnover_per_s=flux / (abundance * 3600), + ecmodel_kcat_per_s=kcat[variants(model, base)[0]], + )) + out = pd.DataFrame(rows) + out["relative_to_highest"] = out["apparent_turnover_per_s"] / out.groupby("complex")["apparent_turnover_per_s"].transform("max") + return out + + +def derived_kcats(turnovers: pd.DataFrame) -> pd.DataFrame: + """The highest apparent turnover of each complex, and the condition it comes from.""" + best = turnovers.loc[turnovers.groupby("complex")["apparent_turnover_per_s"].idxmax()] + return best[["complex", "reaction", "condition", "apparent_turnover_per_s", "ecmodel_kcat_per_s"]].rename( + columns={"apparent_turnover_per_s": "kcat_per_s"}).reset_index(drop=True) + + +def apply_respiratory_kcats(model, kcats: pd.DataFrame) -> list[str]: + """Set each complex's kcat on all its forward variants and rewrite their enzyme coefficients.""" + from geckopy.ec_model.pipeline.apply_kcat import apply_kcat_constraints + + index = {r: i for i, r in enumerate(model.ec.rxns)} + updated = [] + for base, value in zip(kcats["reaction"], kcats["kcat_per_s"]): + for reaction in variants(model, base): + model.ec.kcat[index[reaction]] = float(value) + updated.append(reaction) + apply_kcat_constraints(model, update_rxns=updated) + return updated + + +def main(argv: Optional[list[str]] = None) -> int: + parser = argparse.ArgumentParser(description=__doc__) + parser.add_argument("--results-dir", type=Path, default=RESULTS_DIR) + parser.add_argument("--solver", help=HELP) + args = parser.parse_args(argv) + use_solver(args.solver) + + sampled = pd.read_csv(args.results_dir / "randomSampling" / "allFluxes.tsv", sep="\t").set_index("rxnID") + conditions = load_conditions() + turnovers = apparent_turnovers(load_model(), {c: conditions[c] for c in CONDITION_ORDER}, sampled) + kcats = derived_kcats(turnovers) + generation = args.results_dir / "modelGeneration" + generation.mkdir(parents=True, exist_ok=True) + turnovers.round(6).to_csv(generation / "respiratoryTurnover.tsv", sep="\t", index=False) + kcats.round(6).to_csv(generation / "respiratoryKcats.tsv", sep="\t", index=False) + print(turnovers.round(3).to_string(index=False)) + print() + print(kcats.round(3).to_string(index=False)) + return 0 + + +if __name__ == "__main__": # pragma: no cover + raise SystemExit(main()) diff --git a/src/overflow/run_sampling.py b/src/overflow/run_sampling.py index b6c139a..7f591ed 100644 --- a/src/overflow/run_sampling.py +++ b/src/overflow/run_sampling.py @@ -66,6 +66,7 @@ def run( replace_max_bound: bool = False, min_flux: bool = True, loopless: bool = True, + rate_tolerance: float = 0.05, verbose: bool = True, ) -> dict[str, dict]: """Sample each condition twice and summarise. @@ -100,13 +101,13 @@ def run( model.copy(), condition, n_samples=n_samples, include_formate=False, seed=seed, good_reactions=good_free, n_proc=n_proc, replace_max_bound=replace_max_bound, min_flux=min_flux, - loopless=loopless, + loopless=loopless, tolerance=rate_tolerance, ) full, good_full = sample_condition( model, condition, n_samples=n_samples, include_formate=True, seed=seed, good_reactions=good_full, n_proc=n_proc, replace_max_bound=replace_max_bound, min_flux=min_flux, - loopless=loopless, + loopless=loopless, tolerance=rate_tolerance, ) summary = selected_fluxes( @@ -210,6 +211,10 @@ def main(argv: Optional[list[str]] = None) -> int: "--keep-loops", action="store_true", help="do not tighten reactions to their loop-free range first", ) + parser.add_argument( + "--rate-tolerance", type=float, default=0.05, + help="relative band around each measured rate and the growth rate", + ) parser.add_argument("--solver", help=HELP) parser.add_argument( "--merge", nargs="+", type=Path, metavar="RESULTS_DIR", @@ -239,7 +244,7 @@ def main(argv: Optional[list[str]] = None) -> int: args.conditions, n_samples=args.samples, seed=args.seed, n_proc=args.procs, cache=args.cache, replace_max_bound=args.replace_max_bound, min_flux=args.min_flux, - loopless=not args.keep_loops, + loopless=not args.keep_loops, rate_tolerance=args.rate_tolerance, ) out = args.results_dir / "randomSampling" diff --git a/tests/test_build.py b/tests/test_build.py index fc4d482..e3beb8c 100644 --- a/tests/test_build.py +++ b/tests/test_build.py @@ -54,6 +54,7 @@ def test_the_summary_reports_the_condition(built): table = summary_table([built]) assert list(table["condition"]) == ["CN4"] assert table.loc[0, "growth"] >= 0.099 + assert table.loc[0, "ethanol"] >= 0 @pytest.fixture(scope="module") diff --git a/tests/test_complex_relaxation.py b/tests/test_complex_relaxation.py new file mode 100644 index 0000000..4f7e583 --- /dev/null +++ b/tests/test_complex_relaxation.py @@ -0,0 +1,126 @@ +"""Abundance reconciliation treats an enzyme complex as one unit. + + supply -> S -+- R_E1 (complex E1a + E1b) -+-> P -> biomass + \\- R_E2 (enzyme E2, closed) -/ + +A unit of flux on R_E1 costs 10 mg of each subunit, so the numbers below +can be worked out by hand. +""" +import cobra +import numpy as np +import pytest +from geckopy import EcModel +from raven_toolbox.io.ec_data import EcData +from scipy import sparse + +from overflow.complexes import complex_families +from overflow.flexibilize import ( + apply_concentrations, + minimum_usage_pass, + relax_to_growth, + relax_to_measured_rates, +) +from tiny import protein_coefficient, tiny_adapter + +ENZYMES = ["E1a", "E1b", "E2"] +COST = protein_coefficient(kcat=1.0, mw=36_000.0) # 10 mg per unit flux + + +def complex_model(pool: float = 1000.0) -> EcModel: + model = cobra.Model("tiny_complex") + model.compartments = {"c": "cytoplasm"} + mets = {n: cobra.Metabolite(n, compartment="c") for n in ("S", "P", "biomass", "prot_pool", *(f"prot_{e}" for e in ENZYMES))} + model.add_metabolites(list(mets.values())) + + def reaction(rid, stoichiometry, lb=0.0, ub=1000.0): + r = cobra.Reaction(rid, lower_bound=lb, upper_bound=ub) + r.add_metabolites({mets[m]: c for m, c in stoichiometry.items()}) + return r + + model.add_reactions([ + reaction("EX_S", {"S": 1}, ub=10.0), + reaction("R_E1", {"S": -1, "P": 1, "prot_E1a": -COST, "prot_E1b": -COST}), + reaction("R_E2", {"S": -1, "P": 1, "prot_E2": -COST}, ub=0.0), + reaction("BIO", {"P": -1, "biomass": 1}), + reaction("EX_BIO", {"biomass": -1}), + reaction("prot_pool_exchange", {"prot_pool": 1}, ub=pool), + *(reaction(f"usage_prot_{e}", {"prot_pool": -1, f"prot_{e}": 1}) for e in ENZYMES), + ]) + model.objective = "BIO" + ec_model = EcModel.from_cobra(model, adapter=tiny_adapter()) + ec_model.ec = EcData( + gecko_light=False, rxns=["R_E1", "R_E2"], kcat=np.array([1.0, 1.0]), + source=["test"] * 2, notes=[""] * 2, eccodes=[""] * 2, + genes=[f"gene_{e}" for e in ENZYMES], enzymes=list(ENZYMES), mw=np.full(3, 36_000.0), + sequence=["M"] * 3, concs=np.full(3, np.nan), + rxn_enz_mat=sparse.csr_matrix([[1.0, 1.0, 0.0], [0.0, 0.0, 1.0]]), + ) + ec_model.ec.validate() + return ec_model + + +def concentrations(**values): + return np.array([values.get(e, np.nan) for e in ENZYMES], dtype=float) + + +def test_the_two_subunits_are_one_complex(): + families = complex_families(complex_model()) + assert sorted(families.members("E1a")) == ["E1a", "E1b"] + + +def test_the_minimum_usage_pass_raises_the_whole_complex_by_one_factor(): + model = complex_model() + model.ec.concs = concentrations(E1a=10.0, E1b=40.0) + result = minimum_usage_pass(model, target_growth=5.0, bio_rxn="BIO") + # 5 units need 50 mg of each; E1a needs 1.01 * 50 / 10 = 5.05-fold + raised = dict(zip(ENZYMES, result.concentrations)) + assert raised["E1a"] == pytest.approx(10.0 * 5.05) + assert raised["E1b"] == pytest.approx(40.0 * 5.05) + assert sorted(result.raised) == ["E1a", "E1b"] + + +def test_the_rate_fit_relaxes_the_whole_complex_by_one_factor(): + model = complex_model() + apply_concentrations(model, concentrations(E1a=10.0, E1b=40.0)) + result = relax_to_measured_rates(model, target_growth=5.0, bio_rxn="BIO") + assert result.feasible + folds = {p: r / m for p, m, r in zip(result.proteins, result.measured, result.relaxed)} + assert folds["E1a"] == pytest.approx(5.0) + assert folds["E1b"] == pytest.approx(5.0) + + +def test_a_subunit_measured_at_zero_does_not_inflate_its_complex_in_the_rate_fit(): + model = complex_model() + apply_concentrations(model, concentrations(E1a=0.0, E1b=40.0)) + result = relax_to_measured_rates(model, target_growth=5.0, bio_rxn="BIO") + assert result.feasible + relaxed = dict(zip(result.proteins, result.relaxed)) + assert relaxed.get("E1b", 40.0) == pytest.approx(50.0, rel=1e-6) + + +def test_absolute_weighting_does_not_make_a_zero_measurement_free(): + model = complex_model() + apply_concentrations(model, concentrations(E1a=0.0, E1b=40.0)) + result = relax_to_measured_rates(model, target_growth=5.0, bio_rxn="BIO", weight="absolute") + assert result.feasible + assert result.added_mg == pytest.approx(50.0 + 10.0, rel=1e-6) + + +def test_the_global_relaxation_raises_the_complex_together_and_leaves_the_pool(): + model = complex_model() + apply_concentrations(model, concentrations(E1a=10.0, E1b=10.0)) + result = relax_to_growth(model, target_growth=5.0, bio_rxn="BIO", pool_rxn="prot_pool_exchange") + assert result.reached_target + assert result.pool_increases == 0 + caps = [model.reactions.get_by_id(f"usage_prot_{e}").upper_bound for e in ("E1a", "E1b")] + assert caps == pytest.approx([50.0, 50.0]) + + +def test_the_global_relaxation_grows_the_pool_only_when_it_has_to(): + model = complex_model(pool=60.0) # 5 units need 100 mg in all + apply_concentrations(model, concentrations(E1a=50.0, E1b=50.0)) + result = relax_to_growth(model, target_growth=5.0, bio_rxn="BIO", pool_rxn="prot_pool_exchange") + assert result.reached_target + assert result.pool_increases == 1 + assert model.reactions.prot_pool_exchange.upper_bound == pytest.approx(100.0) + assert result.released == [] diff --git a/tests/test_complexes.py b/tests/test_complexes.py index ee649b4..f191664 100644 --- a/tests/test_complexes.py +++ b/tests/test_complexes.py @@ -5,8 +5,7 @@ import pytest from scipy.sparse import csr_matrix -from overflow.complexes import complex_subunits, fix_complexes -from overflow.config import OXPHOS_RXNS +from overflow.complexes import complex_families, complex_subunits, level_complexes @dataclass @@ -34,50 +33,86 @@ def test_a_base_reaction_matches_all_its_isozyme_variants(): assert [v[0] for v in complex_subunits(model, "r_1")] == ["r_1_EXP_1", "r_1_EXP_2"] -def test_subunits_are_levelled_to_one_abundance_per_complex(): - """Two subunits at 1:1 measured 2 and 4 both become 3.""" - model = _Model(["r_1"], ["P1", "P2"], [[1, 1]]) - result = fix_complexes(model, ["r_1"], ["P1", "P2"], np.array([2.0, 4.0])) - assert dict(zip(result.uniprot_ids, result.abundances)) == {"P1": 3.0, "P2": 3.0} +def _families(rows): + """``rows``: {reaction: {enzyme: copies}} -> (model, families).""" + enzymes = sorted({e for r in rows.values() for e in r}) + matrix = [[r.get(e, 0) for e in enzymes] for r in rows.values()] + model = _Model(list(rows), enzymes, matrix) + return model, complex_families(model) -def test_stoichiometry_scales_the_shared_abundance(): - """A subunit present twice per complex gets twice the abundance.""" - model = _Model(["r_1"], ["P1", "P2"], [[1, 2]]) - result = fix_complexes(model, ["r_1"], ["P1", "P2"], np.array([3.0, 6.0])) - values = dict(zip(result.uniprot_ids, result.abundances)) - assert values["P1"] == pytest.approx(3.0) - assert values["P2"] == pytest.approx(6.0) +def _levelled(model, ids, values): + result = level_complexes(model, ids, np.array(values, dtype=float)) + return dict(zip(result.uniprot_ids, result.abundances)), result + + +def test_subunits_are_levelled_to_the_median_per_copy(): + # per copy: P1 = 1, P2 = 4 / 2 = 2, P3 = 6; median 2 + model, _ = _families({"r_1": {"P1": 1, "P2": 2, "P3": 1}}) + values, result = _levelled(model, ["P1", "P2", "P3"], [1.0, 4.0, 6.0]) + assert values == pytest.approx({"P1": 2.0, "P2": 4.0, "P3": 2.0}) + assert sorted(result.adjusted) == ["P1", "P3"] def test_an_unmeasured_subunit_is_added_at_its_share(): - model = _Model(["r_1"], ["P1", "P2"], [[1, 1]]) - result = fix_complexes(model, ["r_1"], ["P1"], np.array([5.0])) - values = dict(zip(result.uniprot_ids, result.abundances)) + model, _ = _families({"r_1": {"P1": 1, "P2": 1}}) + values, result = _levelled(model, ["P1"], [5.0]) assert result.added == ["P2"] assert values["P2"] == pytest.approx(5.0) def test_a_complex_with_no_measurement_is_left_alone(): - model = _Model(["r_1"], ["P1", "P2"], [[1, 1]]) - result = fix_complexes(model, ["r_1"], ["P3"], np.array([1.0])) - assert result.uniprot_ids == ["P3"] + model, _ = _families({"r_1": {"P1": 1, "P2": 1}, "r_2": {"P3": 1}}) + values, result = _levelled(model, ["P3"], [1.0]) + assert values == {"P3": 1.0} assert result.added == [] -def test_zero_measurements_do_not_drag_the_complex_down(): - """A subunit measured at zero is treated as unseen, not as absent.""" - model = _Model(["r_1"], ["P1", "P2"], [[1, 1]]) - result = fix_complexes(model, ["r_1"], ["P1", "P2"], np.array([4.0, 0.0])) - values = dict(zip(result.uniprot_ids, result.abundances)) - assert values["P1"] == pytest.approx(4.0) - assert values["P2"] == pytest.approx(4.0) +def test_zero_measurements_count_as_unseen(): + model, _ = _families({"r_1": {"P1": 1, "P2": 1}}) + values, _ = _levelled(model, ["P1", "P2"], [4.0, 0.0]) + assert values == pytest.approx({"P1": 4.0, "P2": 4.0}) + + +def test_isozyme_variants_are_one_complex(): + _, families = _families({"r_1_EXP_1": {"A": 1, "B": 1, "C": 1}, "r_1_EXP_2": {"A": 1, "B": 1, "D": 1}}) + assert sorted(families.members("A")) == ["A", "B", "C", "D"] + + +def test_one_shared_protein_does_not_chain_complexes_together(): + _, families = _families({"r_1": {"A": 1, "B": 1}, "r_2": {"A": 1, "C": 1}, "r_3": {"A": 1, "D": 1, "E": 1, "F": 1}}) + assert families.shared == {"A"} + assert families.members("B") == ["B"] + + +def test_a_carrier_in_several_complexes_keeps_its_measurement(): + rows = {"r_1_EXP_1": {"B": 1, "C": 1, "D": 1, "S": 1}, "r_1_EXP_2": {"B": 1, "C": 1, "D": 1, "H": 1}, + "r_2": {"E": 1, "S": 1}, "r_3": {"F": 1, "S": 1}} + model, families = _families(rows) + assert "S" in families.shared + values, _ = _levelled(model, ["B", "C", "D", "S"], [1.0, 1.0, 1.0, 50.0]) + assert values["S"] == 50.0 + assert values["B"] == 1.0 + + +def test_a_subunit_in_two_complexes_belongs_to_the_one_with_more_reactions(): + rows = {"r_1": {"A": 1, "B": 1, "C": 1, "D": 1}, "r_2": {"A": 1, "B": 1, "C": 1, "D": 1}, + "r_3": {"A": 1, "B": 1, "E": 1, "F": 1, "G": 1, "H": 1}} + _, families = _families(rows) + assert sorted(families.members("A")) == ["A", "B", "C", "D"] + assert sorted(families.members("E")) == ["E", "F", "G", "H"] + + +def test_an_enzyme_that_also_works_alone_is_shared(): + _, families = _families({"r_1": {"A": 1, "B": 1}, "r_2": {"A": 1}}) + assert "A" in families.shared @pytest.mark.slow -def test_respiratory_complexes_are_found_in_the_real_model(ec_model): - total = sum(len(complex_subunits(ec_model, base)) for base in OXPHOS_RXNS) - assert total > 0 - for base in OXPHOS_RXNS: - for _, subunits in complex_subunits(ec_model, base): - assert all(s > 0 for _, s in subunits) +def test_the_respiratory_complexes_are_found_in_the_real_model(ec_model): + families = complex_families(ec_model) + complex_iv = families.members("P00401") # COX1 + complex_iii = families.members("P07256") # COR1 + assert "P00410" in complex_iv and "P04037" in complex_iv # COX2, COX4 + assert "P07257" in complex_iii and "P00401" not in complex_iii # QCR2 + assert {"P00044", "P00045", "P09624"} <= families.shared # cytochrome c (CYC1, CYC7), LPD1 diff --git a/tests/test_flexibilize.py b/tests/test_flexibilize.py index ec6cb83..a699a62 100644 --- a/tests/test_flexibilize.py +++ b/tests/test_flexibilize.py @@ -9,9 +9,9 @@ from overflow.flexibilize import ( apply_concentrations, - flexibilize_proteins, measured_enzymes, minimum_usage_pass, + relax_to_growth, write_back_concentrations, ) from tiny import tiny_ec_model @@ -75,55 +75,45 @@ def test_the_pass_does_not_constrain_the_model_it_measures(model): assert model.reactions.get_by_id(f"usage_prot_{enzyme}").upper_bound == 1000.0 -# --- iterative flexibilization --------------------------------------- +# --- relaxing abundances until the dilution rate is reached ---------- -def test_a_limiting_cap_is_released_and_growth_reaches_the_target(model): +def test_the_least_relaxation_reaches_the_target(model): + """10 units need x on E1 (10 mg each) and 10 - x on E2 (5 mg each). + The summed fold increases (2x - 1)+ and (9 - x)+ are smallest at + x = 0.5: E1 stays at 5 mg and E2 is raised to 47.5 mg.""" _set_concentrations(model, E1=5.0, E2=5.0) apply_concentrations(model, model.ec.concs) assert model.optimize().objective_value < 10.0 - result = flexibilize_proteins(model, target_growth=10.0, bio_rxn="BIO") + result = relax_to_growth(model, target_growth=10.0, bio_rxn="BIO") assert result.reached_target assert result.growth == pytest.approx(10.0) - assert set(result.released) <= {"E1", "E2"} - - -def test_a_released_enzyme_is_pulled_back_to_what_it_uses(model): - """Releasing a cap should cost only what the model spends, not the - 1000 mg the release temporarily allows.""" - _set_concentrations(model, E1=5.0, E2=5.0) - apply_concentrations(model, model.ec.concs) - result = flexibilize_proteins(model, target_growth=10.0, bio_rxn="BIO") - - for enzyme in result.released: - bound = model.reactions.get_by_id(f"usage_prot_{enzyme}").upper_bound - assert bound < 1000.0 - table = result.table() - assert (table["modified_mg_gDW"] >= table["previous_mg_gDW"]).all() + assert result.released == ["E2"] + assert model.reactions.get_by_id("usage_prot_E2").upper_bound == pytest.approx(47.5) + assert model.reactions.get_by_id("usage_prot_E1").upper_bound == pytest.approx(5.0) + assert result.pool_increases == 0 -def test_the_pool_is_grown_when_no_single_enzyme_is_limiting(): - """With generous caps but too small a pool, there is nothing to - release, so the budget itself has to give.""" +def test_the_pool_grows_only_when_no_enzyme_relaxation_suffices(): model = tiny_ec_model(pool=10.0, supply=10.0) _set_concentrations(model, E1=1000.0, E2=1000.0) apply_concentrations(model, model.ec.concs) - result = flexibilize_proteins(model, target_growth=10.0, bio_rxn="BIO") - assert result.pool_increases > 0 - assert result.pool_after > result.pool_before + result = relax_to_growth(model, target_growth=10.0, bio_rxn="BIO") assert result.reached_target + assert result.pool_increases == 1 + assert result.pool_after == pytest.approx(50.0) # all on E2, 5 mg per unit + assert result.released == [] -def test_an_unreachable_target_is_reported_rather_than_looped_forever(): +def test_an_unreachable_target_is_reported(): """Supply, not protein, caps this one: no amount of enzyme helps.""" model = tiny_ec_model(pool=1000.0, supply=1.0) _set_concentrations(model, E1=1.0, E2=1.0) apply_concentrations(model, model.ec.concs) - result = flexibilize_proteins(model, target_growth=10.0, max_iterations=20, bio_rxn="BIO") + result = relax_to_growth(model, target_growth=10.0, bio_rxn="BIO") assert not result.reached_target - assert result.growth == pytest.approx(1.0) # --- keeping the record straight ------------------------------------- @@ -145,61 +135,6 @@ def test_applying_concentrations_caps_the_usage_reactions(model): assert model.reactions.get_by_id("usage_prot_E1").upper_bound == 1000.0 -# --- robustness of finding the limiting cap --------------------------- - -def test_the_limiting_cap_is_found_even_when_shadow_prices_are_silent(model, monkeypatch): - """On a degenerate optimum the duals can all come back zero. The - probe has to find the limiting cap anyway, or the search concludes - that nothing is limiting and grows the pool forever.""" - import numpy as np - - import overflow.flexibilize as flexibilize - - def silent(model, proteins=None, **kwargs): - n = len(proteins if proteins is not None else model.ec.enzymes) - return np.ones(n, dtype=bool), np.zeros(n, dtype=float) - - monkeypatch.setattr(flexibilize, "get_conc_control_coeffs", silent) - - _set_concentrations(model, E1=5.0, E2=5.0) - apply_concentrations(model, model.ec.concs) - result = flexibilize_proteins(model, target_growth=10.0, bio_rxn="BIO") - - assert result.reached_target - assert result.released, "no cap was released despite one being limiting" - assert result.pool_increases == 0 - - -def test_binding_caps_ignores_enzymes_that_are_already_free(model): - from overflow.flexibilize import binding_caps - - _set_concentrations(model, E1=5.0, E2=5.0) - apply_concentrations(model, model.ec.concs) - solution = model.optimize() - assert set(binding_caps(model, solution, 1e-6)) <= {"E1", "E2"} - - model.reactions.get_by_id("usage_prot_E2").upper_bound = 1000.0 - solution = model.optimize() - assert "E2" not in binding_caps(model, solution, 1e-6) - - -def test_a_stalled_search_gives_up_instead_of_inflating_the_pool(model, monkeypatch): - """Growing the protein budget without ever gaining growth means the - budget is not the constraint; the run should stop and say so rather - than leave behind a model with an invented pool.""" - import overflow.flexibilize as flexibilize - - monkeypatch.setattr(flexibilize, "_most_limiting", lambda *a, **k: None) - - _set_concentrations(model, E1=5.0, E2=5.0) - apply_concentrations(model, model.ec.concs) - result = flexibilize_proteins( - model, target_growth=10.0, bio_rxn="BIO", patience=5, max_iterations=500 - ) - assert not result.reached_target - assert result.pool_increases <= 7 - - # --- relaxing abundances until the measured rates fit ---------------- def test_the_least_relaxation_that_meets_the_target_is_found(model): diff --git a/tests/test_model_integrity.py b/tests/test_model_integrity.py index 660e2bd..e1eac81 100644 --- a/tests/test_model_integrity.py +++ b/tests/test_model_integrity.py @@ -11,13 +11,15 @@ CO2_RXN, NGAM_RXN, O2_RXN, - OXPHOS_RXNS, POOL_RXN, PROTEIN_RXN, ) pytestmark = pytest.mark.slow +#: Succinate dehydrogenase, complexes III and IV, ATP synthase. +OXPHOS_RXNS = ("r_1021", "r_0439", "r_0438", "r_0226") + def test_model_is_a_full_ecmodel(ec_model): assert ec_model.ec.gecko_light is False diff --git a/tests/test_respiratory_kcats.py b/tests/test_respiratory_kcats.py new file mode 100644 index 0000000..13215ff --- /dev/null +++ b/tests/test_respiratory_kcats.py @@ -0,0 +1,53 @@ +"""Respiratory-chain kcats derived from the sampled fluxes and the measured complexes.""" +import numpy as np +import pandas as pd +import pytest + +from overflow import load_model +from overflow.config import RESULTS_DIR +from overflow.respiratory_kcats import ( + COMPLEXES, + apparent_turnovers, + apply_respiratory_kcats, + derived_kcats, + variants, +) + +pytestmark = pytest.mark.slow + + +def test_the_derived_kcat_is_the_highest_turnover_and_names_its_condition(): + turnovers = pd.DataFrame({ + "condition": ["a", "b", "a", "b"], + "complex": ["complex III", "complex III", "complex IV", "complex IV"], + "reaction": ["r_0439", "r_0439", "r_0438", "r_0438"], + "apparent_turnover_per_s": [100.0, 300.0, 50.0, 20.0], + "ecmodel_kcat_per_s": [290.0, 290.0, 1376.0, 1376.0], + }) + kcats = derived_kcats(turnovers).set_index("complex") + assert kcats.loc["complex III", "kcat_per_s"] == 300.0 + assert kcats.loc["complex III", "condition"] == "b" + assert kcats.loc["complex IV", "condition"] == "a" + + +def test_every_complex_has_a_finite_turnover_in_every_condition(ec_model, conditions): + sampled = pd.read_csv(RESULTS_DIR / "randomSampling" / "allFluxes.tsv", sep="\t").set_index("rxnID") + turnovers = apparent_turnovers(ec_model, conditions, sampled) + assert len(turnovers) == len(conditions) * len(COMPLEXES) + assert np.isfinite(turnovers["apparent_turnover_per_s"]).all() + assert (turnovers["apparent_turnover_per_s"] > 0).all() + assert np.allclose(turnovers.groupby("complex")["relative_to_highest"].max(), 1.0) + + +def test_applying_changes_only_the_respiratory_complexes(): + model, reference = load_model(), load_model() + kcats = pd.DataFrame({"reaction": ["r_0438"], "kcat_per_s": [2 * float(model.ec.kcat[list(model.ec.rxns).index("r_0438_EXP_1")])]}) + updated = apply_respiratory_kcats(model, kcats) + assert set(updated) == set(variants(model, "r_0438")) + for rid in updated: + new = {m.id: c for m, c in model.reactions.get_by_id(rid).metabolites.items() if m.id.startswith("prot_")} + old = {m.id: c for m, c in reference.reactions.get_by_id(rid).metabolites.items() if m.id.startswith("prot_")} + assert new.keys() == old.keys() + assert all(np.isclose(new[k], old[k] / 2) for k in new) + untouched = reference.reactions.get_by_id("r_0439_EXP_1").metabolites + assert {m.id: c for m, c in model.reactions.get_by_id("r_0439_EXP_1").metabolites.items()} == {m.id: c for m, c in untouched.items()} diff --git a/tests/test_summary.py b/tests/test_summary.py new file mode 100644 index 0000000..fc965ba --- /dev/null +++ b/tests/test_summary.py @@ -0,0 +1,31 @@ +"""The build summary keeps the rows of conditions built separately.""" +import pandas as pd + +from overflow.build import update_summary + + +def rows(*conditions, growth=0.1): + return pd.DataFrame({"condition": list(conditions), "growth": growth}) + + +def test_conditions_built_one_at_a_time_all_end_up_in_the_summary(tmp_path): + path = tmp_path / "modelGeneration" / "summary.tsv" + for name in ("hGR", "CN22", "CN4"): + update_summary(path, rows(name)) + table = pd.read_csv(path, sep="\t") + assert list(table["condition"]) == ["CN4", "CN22", "hGR"] + + +def test_a_rebuilt_condition_replaces_its_row(tmp_path): + path = tmp_path / "summary.tsv" + update_summary(path, rows("CN4", "CN22", growth=0.1)) + table = update_summary(path, rows("CN22", growth=0.2)) + assert list(table["condition"]) == ["CN4", "CN22"] + assert list(table["growth"]) == [0.1, 0.2] + + +def test_conditions_outside_the_order_follow_it(tmp_path): + path = tmp_path / "summary.tsv" + update_summary(path, rows("mu010")) + table = update_summary(path, rows("CN75")) + assert list(table["condition"]) == ["CN75", "mu010"]